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Informačný list ECTS Sylabus
Sylabus předmětu I1-OPT2 - Optimization 2 (FCE - SS 2019/2020)
Slovenština Angličtina
|Slovak University of Technology in Bratislava
|Faculty of Civil Engineering
|Course unit code:
|Course unit title:
|Optimization 2
|Mode of delivery, planned learning activities and teaching methods:
|Credits allocated:
|Recommended semester/trimester:
|Mathematical and Computational Modeling - master (compulsory), 2. semester
|Level of study:
|Prerequisites for registration:
|Assesment methods:
|Semestral projects. Passmark 56%
|Learning outcomes of the course unit:
|Students will learn basic methods of dynamic programming and Bellman principle of optimality. They will be able to handle stochastic optimization problems in real life applications.
|Course contents:
|• Classification of optimization problems.
• Continuous and discrete optimization.
• Dynamic programming and applications, Belmann principle of optimality.
• Stochastic optimization - simulated annealing.
|Recommended or required reading:
|Language of instruction:
|slovak or english
|Courses evaluation:
|Assessed students in total: 33
|Name of lecturer(s):
|prof. RNDr. Martin Knor, PhD. (examiner, instructor, lecturer) - slovak, english
prof. RNDr. Jozef Širáň, DrSc. (person responsible for course)
Ing. Mgr. Lukáš Tomek, PhD. (examiner, instructor)
|Last modification:
|16. 4. 2019
|prof. RNDr. Jozef Širáň, DrSc. and programme supervisor
Last modification made by Ing. Peter Korčák on 04/16/2019.


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Some days, "woke up on the wrong side of the bed" isn't quite enough to express how unpleasant my mood is. Most of my bad days involve an overabundance of feels, and today the feels make me want to punch everyone. (Of course, I wouldn't. But still.*)
My usual solution is to go for a long, hard run to burn off some feels. But my legs are still awfully sore, so I debated doing something else. In the end, though, I went and ran, battling soreness up hills. It was only 30 minutes, but I think it might be enough to get me through the day. I hope.
Yesterday evening I spent trying about everything to work out the knot in my quad, above my knee– tennis ball, frozen peas, a good rubdown with Tiger Balm. It feels a little better today; I'll have to keep it up.
* Any angry, violent feels may get turned against myself if I can't get them under control. It veers between rageful and frustrated sadness. If I can ride the line between, I'll be fine.

subset: commoncrawl


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I designed this dually as one of my tutorials on GhettoRigIt.com (my very first web site!) and for my World Civilizations I final project. I began by attempting to make it in Photoshop but soon realized that I would have much better luck (and increased adaptability) if I did it in 3D. So, I guess this is just to show off that I know how to model simple things in 3D. I did this in SketchUp. I am currently learning 3DS Max 9.
If you'd actually like to make this trebuchet, I have the full tutorial online at GhettoRigIt.com.


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Our website uses functions of the XING network. The provider is XING AG, Dammtorstraße 29-32, 20354 Hamburg, Germany. Each time one of our pages containing Xing functions is accessed a link is created to Xing servers. To our knowledge, no personal data are stored in the process. In particular no IP addresses are stored or user behavior analyzed.
You can find more information on data protection and the Xing Share button in Xing's privacy policy at http://www.xing.com/app/share?op=data_protection.


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The source supplier of bearings has a need to be OEM approved. In offering its OEM customers and distribution networks custom made bearings there is a need to be able to source and supply high quality industrial products at the best prices possible. An extensive inventory of product, parts and components should be backed up with a highly qualified engineering support team. The supply of standard bearing always on time becomes a non sequitur.
And there should never be any excuse for not being able to deliver the goods on time. This, no doubt, is how you would feel as an industrial customer. Of course, you should be expecting reasonable delivery timeframes, particularly if your bearings supply has come from abroad. You could expect the delivery of your customized parts and components within ninety days. This could take into account all types of applications, industries and its related challenges.
As a discerning and competitive industrialist, you should be in the market for high quality or well-known brand bearings. These should be supplied to you in its original packaging, sourced from best known networks from around the world. Power transmission products, if required, could also be supplied. These again should be meeting highest standards of industry-specific qualities. Innovative engineering and the use of superior materials, and with unbridled performance, should be par for the course.
Perhaps this has to do with the sought after quality, but there is an imperative to not supply bearings simply in bulk. Perhaps you can already appreciate this imperative. It is something you seek to maintain for your business, not so. Now, benefits accrue for those who continue to lean on high grade suppliers of not just bearings but sprockets, roller chains, inserts and all its related parts too.Read More


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Improve Business Telemarketing - 4 Steps
To improve business telemarketing sales calls, it is best to view the process from the perspective of the business contact. Whether the contact is a sales prospect or existing customer, the time spent in the conversation should be a valuable investment by both parties. Time is a resource that you and the business contact do not wish to waste.
Here a four recommendations that you can use to improve business-to-business telemarketing that will result in higher productivity and sales.
Listen | Listen
To improve business telemarketing sales calls starts with the most basic of steps: get information, establish trust, credibility and some level of personal connection. Since this process is completely non-visual, it is strictly a matter of verbal communication between you and the business contact.
Your basic rule of guidance should be to talk less and listen more.
Recent research indicates that the most successful telemarketing sales people talk about 43% of the time and listen to the business contact the remainder (57%) of the telephone conversation. They recognize that the business contact is the most important party in this conversation.
You should make the business contact the focal point by asking questions, listening, and learning to determine what his/her potential business needs are and whether there is a fit for what your business has to offer. If the business contact feels that your are actively listening, you will establish personal rapport and credibility.
Ask Directed | Open Ended Questions
Your telephone conversation with the business contact has an ultimate goal. This goal might be a new customer, sale, business referral, problem resolution, etc.
The questions that you ask should be the right questions directed toward achieving this goal. For the most part, they should be open-ended (responses that are not a "yes" or a "no") so that business contact talks providing information while you actively listen. For example:
Visualize The Solution
Changing your perspective to that of the business contact will help you improve business telemarketing sales calls. Using directed, open-ended relevant questions will help reveal the business contact's issues, objectives, pain and potential solutions.
What does the business contact desire his/her situation to be like after a potential solution? Your goal is to help the business contact visualize how much better life would be with your solution, and the pain of not solving the problem.
Once the business contact can internalize the solution as being his/her decision, it then becomes a natural process of your helping implement the solution.
Why Different?
The business contact needs to understand what makes your solution (product or service) different and why that matters. You need to answer the question, "Why will I be better off if I work with you and your company rather than someone else?"
You should anticipate and proactively address this topic with the business prospect: " I would like to explain why working with me and my company would be in your best interests…"
CONCLUSION - Improve Business Telemarketing
Four steps are presented how to improve business telemarketing sales calls. These steps are basic. 1) You should let the business prospect talk more while you actively listen. 2) Ask the business contact relevant, directed, open-ended questions to foster information sharing and rapport toward achieving your particular goal. 3) Guide the business contact to visualize the solution that you can provide. And 4) help the business contact clearly understand why you and your business solution are the right choice to resolve his/her pain.
Please call us at (888) 339-6699 to discuss which call-center outsourcing service will serve your business needs or Contact Us.


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Living Dead Dolls Series 33 Moulin Morgue "Larmes De Sang"
Welcome to Moulin Morgue — the Mill Morgue, where the elite and the informed gather for an evening of cabaret and carnage. Here, the girls are beautiful and the razors sharp. Our theatre troupe combines the lavish decadence of the Moulin Rouge with the ghoulish delights of the Grand Guignol.
The stars of tonights performance are:
Chipboard Poem:
Blood drips down from her face in rouge,
Do they fall from tears or an open wound?
Is the terror real or all just part of the show?
Not until you see your own will you know.
Each doll comes in a black sealed coffin with red tissue paper lining the coffin. The coffin measures 12 inches length, 6 inches width, and 4 inches depth. Each doll is sold separately. Each individually packaged in their own coffin…for now.
*See Second Picture below for the doll inside it's box, and full group pic.
This product was added to our catalog on Friday 03 March, 2017.


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Would you consider not 'backing up' your computer files? What would happen to your contractor's license if your qualifier quit like an outdated hard drive? I will 'quantify' the value of being 'responsible' and, finally cry out on another contractor's 'taxing' situation… Q: Thank you for speaking with me about securing a "back-up" license for … Continue reading Back Up Licenses, Qualifiers and Liens
Month: January 2010
General Licenses, Disassociation & LLC Filing
We will get down to business by the 'numbers' as a contractor discovers he may "B" off the mark in getting that general license. What happens to the contractor's license when a business is 'dead'? Does the license 'live on' to cause problems in the future? Not knowing may be an expensive lesson to learn… … Continue reading General Licenses, Disassociation & LLC Filing
Unlicensed Penalties, Suspensions and LLC's
The new calendar will put a smile on the face of many readers as it brings an 'Unhappy New Year' for unlicensed contractors. The 'mystery' of an unexpected letter from the CSLB sets a 'suspense' story in motion. Another general contractor wants to 'root out' some serious problems with his plan of action… Q: I … Continue reading Unlicensed Penalties, Suspensions and LLC's
Electrical & General Licenses
I want to wish all my readers a Happy and Prosperous 2010. This last year has been a rough one for the construction industry. As we look forward to this New Year, let us hope that the perceived economic turn-a-round is real and the potential for recovery realized in the marketplace… Q: I have heard … Continue reading Electrical & General Licenses


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Much like the GP-500, the CASIO GP-300 also produces the finest nuances of the world's most famous grand pianos. The high-quality amplifier system with six speakers creates a complex sound – a sound familiar from acoustic grand pianos.
Instrument for a top-class musical experience
Features such as 26 sounds, Concert Play function and Hall Simulator leave almost nothing to be desired for ambitious piano playing.
This model was developed in collaboration with C. Bechstein.
Colour variations
Availability of models and/or line-ups may differ depending on the country or region.
Technical amendments and errors excepted.


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Job description:
Designing and applying bioinformatics data analysis tools to challenges in Life Science
Working closely with the US and EU based customers to improve their cutting edge R&D solutions
Example projects include implementation of new algorithms in R/Python for experimental datasets or building custom analysis pipelines
- PhD or MSc degree (might be the final year of Master's program) in bioinformatics, computer science/programming
- Knowledge of NGS data analysis (DE, Chip-Seq, RIP-Seq, CNV, SNP, assembly), bioinformatics sequence analysis methods
- Fluent in Python or R
You get extra points for:
- Knowledge of microbiome analysis methods
- Knowledge of the newest findings in immunotherapy
- Knowledge of the 3rd and 4th generation sequencing methods (PacBio, Nanopore)
- Hands-on experience with projects in Data Science, Machine Learning, Big Data, Data Mining
We offer:
- Solving challenging tasks
- An opportunity to contribute to breakthrough solutions in the fight against cancer
- Developing skills in a team of experts, scientists and people with passion for their craft
- Participation in trainings, conferences, etc.
- Working with innovative companies from the US and EU
- Friendly, informal working atmosphere and flexible working hours
Salary: 3500 – 6000 PLN netto
We kindly ask you to add the following clause to your application: "I hereby express my consent to the processing of my personal data by Ardigen S.A. for the purpose of existing recruitment process". If you want us to keep the submitted documents also for the purposes of future recruitment processes, we kindly ask you to add the following clause to your application: "I hereby express my consent to the processing of my personal data by Ardigen S.A. for the purpose of future recruitment processes for a period of 3 years from the date of submission of this document, in order to analyse them in terms of the recruitment processes carried out in Ardigen."
Apply here.


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Malware and other info discovered in subway 'lost and found' flash drives
At one point in your life, you lose something valuable – your wallet, cash, pieces of jewelry, etc. This is a common scenario that all of us share. We tend to misplace and lose things due to human error and carelessness. I, for one, had lost a couple of loose coins and change while I'm on the road.
Same goes for our devices and its peripherals. As what we keep telling ourselves, there are situation that is beyond our control and we can't help it. And I think the worst excuse that I've given myself when I lost my phone was "it was fated to be lost anyway".
But a lot of us don't know that a simple human error expose us to a lot of dangerous possibilities that can endanger our finances, social standing, or worse, us and our loved ones' lives. I wrote a couple of times about incidents concerning devices lost that lead to a harrowing situation. Most of the time, these are memory peripherals that were stolen or misplaced. But what's alarming is that these devices contain information and data that should have been hidden from others. There were news that a police department allegedly lost a flash drive that contains names, addresses, and information of witnesses related to drug-related cases. Although there are still no reports that the said people involved were harassed or threaten because of the said incident, there is a big possibility in the future that the device may fall into the wrong hands and be used for something illegal and criminal.
On my recent search on the Internet, I found this article about a security firm testing 'lost and found' flash drives from the subway.
Sophos, a known security firm conducted a test on 50 flash drives bought from RailCorp's property auction. Most of these devices were lost or left behind by the owners and were not claimed. The results were pretty interesting and horrifying at the same time. According to Sophos, two-thirds of these devices were infected by malware. These devices also have viruses and worm like Autorun.inf.
But the scary part is the files and data that were found inside these drives. There are a lot of photos and videos, text files, web files, and many more stored on these devices. And it is not just some random or common data, there are sensitive information that were saved on these memory components like tax deductions, minutes of the meeting from an activist group, school and university assignments, and other documents. Some of the things stored inside seem harmless, but the fact that they contained information that might lead someone to track your whereabouts is something to worry about.
But there are always ways to prevent this from happening. Some of them are pretty simple but usually ignored due to carelessness. First is to make sure that your devices are well hidden and kept safe. If you are in a habit of carrying them, put them inside the safest place in your bag or purse. Also, it would be best to get a device that has a password-protect feature like the SanDisk CZ71 Cruzer Force USB Flash Drive. This one has a Secure Access Software that makes it easy to encrypt your folders and files.
Safety should be applied to all, including your devices as these can be used against you.


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The inexpensive Honor 7X will be getting Face Unlock functionality in Q1 2018
Honor announced yesterday the global availability of its View 10 and 7X smartphones, but it also introduced the limited edition Honor 7X Red, which will be available in limited quantities (20,000 units) in select markets.
The Honor 7X that made its debut in the United States last month is great value for money. At just $200, it offers more than decent specs, but if that's still not enough to make you buy one, maybe Honor's next announcement will.
The company has just announced that the entire lineup of Honor 7X devices will receive a new facial recognition and unlocking functionality, also known as Face Unlock. The new feature will be delivered through an OTA update starting in Q1 2018.
Apparently, Honor 7X will be the cheapest smartphone to include such functionality, so the more reason to grab one if you're in need of an inexpensive Android device with a mix of premium features.
source: Honor


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40-Years of Roofing Experience
We base our business on - Hard Work, Honesty, Integrity, Respect, Teamwork, Performance, and Improvement -
"The Best Value For The Customer".
Repair & Installation
Commercial Roofing
If you're looking online for a Commercial Roofing Contractor in Orange County, then look no further! At Gotcha Covered Roofing, we can supply you or property managers with an accurate detailed on-site estimate to repair or replace your roof on-time and within budget.
We are among one of the oldest roofing companies in Orange County. We are continually trained to ensure the latest installation and product techniques are used on your property. We provide commercial roofing services for some of the prime commercial property owners in Orange County. Call Gotcha Covered Roofing today for a fast free onsite written estimate.
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Metal roofs are resistant to extreme weather conditions. Available in two types...READ MORE
Asphalt Roof
The most common residential roofing material used in the United States, asphalt...READ MORE
Synthetic Roof
There are now synthetic roofing products, including rubber, plastic and polymer ...READ MORE


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|Coordinates: 12°22′N 069°10′W / 12.367°N 69.167°WCoordinates: 12°22′N 069°10′W / 12.367°N 69.167°W
|Kingdom of the Netherlands
Westpunt is the name of the westernmost point of the island of Curaçao (a country within the Kingdom of the Netherlands in the Caribbean), and is also the name of a nearby small town, the island's northernmost settlement. The island's northernmost point, Watamula lies two kilometres to the northeast. Westpunt is also a beach on the island of Curaçao. Close by are the coral gravel beaches of Playa Kalki, Playa Forti, Playa Gipy, Grote Knip and Kleine Knip.
Westpunt is known for excellent scuba diving, and is home to several shore and boat dive sites including a submerged airplane wreck and beautiful reefs.[1] Most of tourist accommodation in Westpunt caters to scuba divers and offers excellent infrastructure. A dive center in Playa Kalki is available.
|This Curaçao location article is a stub. You can help Wikipedia by expanding it.


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Caro(a) Colega,
hoje inicia-se o curso sobre Introdução ao controle industrial, oferecido pelo CEC – Continuing Education Center numa parceria entre o IEEE, o site de conteúdo Design News e patrocinado pela Digikey. Confira a resenha:
According to Marketsandmarkets report, the micro and nano Programmable Logic Controllers (PLCs) products will be an 8.89 billion market by 2022. The Global PLC market will grow at a CAGR (Compound Annual Growth Rate) of 9.23 percent over the period of 2013-2018 forecasted by TechNavio's analyst. Manufacturing plants use Programmable Logic Controllers in a variety of industry applications ranging from process control to robotics and automation systems. Non industrial applications include home security systems, traffic light controllers, and entertainment animatronics. Programmable Logic Controllers or PLCs are industrial computers that can read a multitude of input wired sensors and digital signals, process the data, and control electrical, electronic, and electromechanical loads.
In this course, participants will explore the inner workings of PLCs by software setup installation, and writing Ladder Logic and Structure Text Language (STL) programs using bit instructions, timers, counter, and conditional statements to read analog sensors, digital switches, and control LEDs, solid state relays, electromechanical relays, and dc motors.
Aproveite! Clique na figura a seguir para fazer a sua inscrição ou obter mais informações.
consulte sempre um engenheiro eletrônico


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Product Description
Countrywide Yarns Angel Babe 4ply
60% supersoft acrylic 40% nylon
approx 420m
knits on 3.25mm
machine washable
Easy care machine wash baby yarn in 2 solid and 4 multi pastel shades, ideal for baby. Supersoft yarn suitable for all your baby knit projects. Knits to any 4 ply pattern, always best to check your tension against the pattern.


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Below is the CME information for this project.
Accurate Interpretation of HRCT in the Diagnosis of IPF
- CME Released: December 31, 2014
- This program is no longer eligible for CME Credit
- Media: Internet
- Time to Complete: 4 hours. If a participant cannot complete the activity in a single session, he/she can log out and log back in at a later time; responses and progress will be saved.
Upon completion of this educational activity, participants will be able to:
- Define the CT categories of "Definite UIP," "Possible UIP," and "Inconsistent with UIP," as described by American Thoracic Society/European Respiratory Society criteria
- Differentiate the above three categories of UIP on HRCT images
- Differentiate traction bronchiolectasis from honeycombing on HRCT
- Recognize common diffuse interstitial lung disease radiographic patterns that can mimic UIP/IPF
Target Audience
This activity has been designed to meet the educational needs of radiologists, pulmonologists and other physicians involved in the diagnosis and care of patients with idiopathic pulmonary fibrosis.
Accreditation Statement
National Jewish Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
This program is no longer eligible for CME Credit
ABR Self-Assessment Activity
This course meets the American Board of Radiology's (ABR's) criteria for a self-assessment activity in the ABR Maintenance of Certificate program and is designated for 4.0 SA-CME Credits.
Program Support
This activity is supported by an independent educational grant from Boehringer Ingelheim Pharmaceuticals, Inc. and InterMune, Inc. Additional support provided through the generosity of Janeen Naifeh in memory of her husband, Robert Naifeh.
Faculty & Disclosure / Conflict of Interest Policy
In accordance with ACCME requirements, National Jewish Health has a conflict of interest policy that requires faculty to disclose relevant financial relationships related to the content of their presentations/materials. Any potential conflicts are resolved so that presentations are evidence-based and scientifically balanced.
- Jonathan H. Chung, MD
- Faculty Chair
- Associate Professor
- Department of Radiology
- Director of Radiology Professional Quality Assurance
- Head of MRI
- Director of Cardiopulmonary Imaging Fellowship
- National Jewish Health
- Jonathan H. Chung, MD, discloses a relationship with Siemens AG in the form of grants and has received royalties from Amirsys.
- Gregory P. Cosgrove, MD
- Associate Professor
- Division of Pulmonary, Critical Care and Sleep Medicine
- Endowed Chair in Interstitial Lung Disease
- National Jewish Health
- Associate Professor
- Division of Pulmonary Sciences and Critical Care Medicine
- University of Colorado Denver
- Chief Medical Officer, Pulmonary Fibrosis Foundation
- Gregory P. Cosgrove, MD, discloses he is a consultant and on an advisory board for the Pulmonary Fibrosis Foundation and a consultant for Boehringer Ingelheim and InterMune/Genentech/Roche.
- David A. Lynch, MD
- Professor
- Department of Radiology
- National Jewish Health and University of Colorado Denver
- Co-Director, Department of Radiology
- National Jewish Health
- David A. Lynch, MD, discloses he is a consultant for Parexel Imaging, Boehringer Ingelheim, Genentech, Gilead, and Intermune. He is an investigator for Siemens and NHLBI.
Faculty Reviewer
- Esther Langmack, MD, FCCP, CHCP
- Associate Professor
- Department of Medicine
- Medical Director, Office of Professional Education
- National Jewish Health
- Dr. Langmack has no financial interests/relationships or affiliations in relation to this activity
- Andrea Harshman, MHA, CHCP
- Director, Office of Professional Education
- National Jewish Health
- Ms. Harshman has no financial interests/relationships or affiliations in relation to this activity.
CME/CE Disclaimer
National Jewish Health ("NJH") and its officers, Board of Directors, faculty, employees, representatives, and other agents (collectively, "NJH Parties") shall not be responsible in any capacity for, and do not warrant any content whatsoever, in any NJH publication or other product (in any medium), or the use or reliance on any such content, and expressly disclaim any and all liability for such content. All such responsibility for content and use of product solely rests with the authors or the advertisers, as the case may be.
By way of example, without limiting the foregoing, this disclaimer of liability applies to the accuracy, completeness, effectiveness, quality, appearance, ideas, or products, as the case may be, of or resulting from, any statements, references, articles, positions, claimed diagnosis, claimed possible treatments, services, or advertising, express or implied, contained in any NJH live meeting, publication, online course or other product.
Furthermore, the content should not be considered medical advice and is not intended to replace consultation with a qualified medical professional. Under no circumstances, including negligence, shall any of the NJH Parties be liable for any DIRECT, INDIRECT, INCIDENTAL, SPECIAL or CONSEQUENTIAL DAMAGES, or LOST PROFITS that result from any of the foregoing, regardless of legal theory and whether or not claimant was advised of the possibility of such damages.
Hardware/Software Requirements
To access these activities, users will need:
- A computer with an Internet connection.
- Internet Explorer 10 or higher, Firefox 8 or higher, Safari 6 or higher, or any other W3C standards compliant browser.
- Adobe Flash Player and/or an HTML5 capable browser for video playback.
- Adobe Acrobat Reader.
For optimum results we recommend a device that has a display capability of 1024 x 768 or better. Mobile devices are not recommended for this activity.
Contact Information
For questions regarding this activity, please contact the Office of Professional Education at National Jewish Health: 303.398.1000 or firstname.lastname@example.com.


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Our Firm
Jamie Ford
James Ford joined Vista Equity Partners in 2000 and is a Managing Director and President of Vista Public Strategies ("VPS"). Mr. Ford helped found and currently manages VPS. In addition, Mr. Ford is a member of the VPS Advisory Board, and Vista's Compliance Committee. Previously, Mr. Ford served as Vista's Chief Operating Officer and as President of Vista Credit Partners. Mr. Ford was also actively involved in Vista Private Equity Funds' investments in Accero, Aspect Communications, DealerSocket, Misys, P2 Energy Solutions, TIBCO, Turaz, Websense, Ventyx, SER, SourceNet Solutions, SRC Software, and The ACTIVE Network.
Prior to joining Vista, Mr. Ford worked in the Mergers and Acquisitions group of Goldman, Sachs & Co., where he advised clients in a variety of industries, including consumer products, chemicals, energy and power, and media. In addition to his work at Vista, Mr. Ford also serves as a Board member of SquashDrive and of the Boys & Girls Clubs of San Francisco.
Executive AssistantKatie Thomas


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SAN DIEGO – Dec. 9, 2014 – San Diego REPertory Theatre's (San Diego REP) production of "Honky" by Greg Kalleres and directed by Sam Woodhouse was recently filmed as a pilot episode for "OnStage in America," a brand-new primetime television series set to air nationally on public television.
The mission of "OnStage in America" will tape and broadcast the very best productions from American regional theatre in a fresh and exciting format. The show, funded by a successful Kickstarter campaign last January, highlights productions using innovative filming techniques allowing viewers to experience the depth and drama of the most creative productions on the stage in the United States. This will allow the San Diego REP's production of "Honky" to be brought right into the living rooms of a fresh new set of audiences.
After the national broadcast on public television, the taping of "Honky" will become part of a digital library, viewable for on-demand, streaming, and other digital distribution allowing these productions to live on for all prosperity.
"Our production of 'Honky' being selected by 'OnStage in America' to be the pilot production for a new national television series means a great deal to the artists and staff of San Diego REP," says Sam Woodhouse, co-founder and artistic director, San Diego REP. "We are proud and grateful that OnStage in America has recognized the high quality of our artistic work and our role as an important player in the landscape of professional regional theatre in America."
About "Honky" at San Diego REP
The New York Times calls "Honky" "a hilarious play by Greg Kalleres… keeps you laughing from start to finish." Inspired by his experience as a writer of TV commercials, Kalleres' satire begins with the shooting death of a young black teenager because of his trendy new "Sky Max" basketball shoes, echoing incidents that occurred in 1989 over Air Jordan shoes. "Honky" is comedy about race, consumerism, marketing and a drug that can claims to cure racism.
"Honky" ran Saturday, Nov. 15 through Sunday, Dec. 7, 2014 in the Lyceum Space. Sam Woodhouse, co-founder and artistic director, San Diego REP, directed. Jacole Kitchen served as assistant director. Cast included: Gerard Joseph as Thomas; Jacque Wilke as Andie; Fran Gercke as Peter; James Newcomb as Davis; Tanya Alexander as Emilia; Jacob Bruce as Dr. Driscoll/Abraham Lincoln; Deleon Dallas as Kid #1/Frederick Douglass; and Cortez Johnson as Kid #2.
Learn more about "OnStage America" here.
About San Diego REPertory Theatre
San Diego REPertory Theatre (San Diego REP) produces intimate, exotic, provocative theatre. We promote a more inclusive community through vivid works that nourish progressive political and social values and celebrate the multiple voices of our region. Founded in 1976, San Diego REPertory Theatre is downtown San Diego's resident theatre, promoting a more inclusive community through work that nourishes progressive political and social values. The company produces and hosts over 300 events and performances year-round on its three stages at the Lyceum Theatre. Since moving to the Lyceum, the REP has produced 45 main stage productions by Latino playwrights, and more than 40 world premieres. The company has received more than 200 awards for artistic excellence from the San Diego Theatre Critics Circle, Patté Theatre Awards, NAACP, Backstage West, Dramalogue, and StageSceneLA. In 2005, the San Diego Theatre Critics Circle presented the REP with the Craig Noel Award "For 30 Years of Artistic Dedication to Downtown and Diversity." San Diego REPertory Theatre feeds the curious soul. To learn more about San Diego REPertory Theatre, to purchase tickets, or make a donation, visit www.sdrep.org. Join us on Facebook and follow us on Twitter.


text: I am struggling at the moment - I know what I want to be (an author), but though I have a plan for how to get there I'm not there yet. I feel like I'm in an extended period of metamorphosis. It's nearly five years since I last worked in an office, and seven since... Continue Reading →


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And performing in said premiere episode? Why, it's Dallas' own St. Vincent, of course.
(What? You thought her show had passed, so we must be done? I laugh at you. Laugh, laugh.)
If you like this story, consider signing up for our email newsletters.
You have successfully signed up for your selected newsletter(s) - please keep an eye on your mailbox, we're movin' in!
Anyway, it's a nice little feature. So check out the above clip of Annie Clark and her band performing "The Party"--it'll give you a nice idea of the group's live arrangements if you missed Thursday's show. And, if ya dig that one, check out "Actor Out Of Work," too. Although, to be honest, of the two, I much prefer the one above.


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Browse these delicious and easy appetizers for a crowd. These simple appetizers are perfect every occasion and will add up to a stress-free party or get-together.
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Combining European styling with American engineering, HOIST® takes commercial free weight equipment to a whole new level. The new CF Line features the same aesthetic distinction and durable construction as the popular HOIST ROC-IT™ line.
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The LED beads are capable of delivering immense brightness and a wider angle. This light uses a DC power supply, but can also be powered by a strap-type battery backup. Use the 2.4 GHz wireless remote control to dim the light from distances of up to 15 m, as well as to switch on or off the light.Since the LED light has a dimming range of 1-100%, you won't have to move the light once it is perfectly positioned. Light Source: 320 LED lamp beads and 40 RGB SMD lamps. Color Rendering Index(CRI): =95. You will feel easy and safe to do business with us. USA 2-8 days Arrive, UK 2-4 days. This information is provided by the carrier and excludes weekends and bank holidays. Pls contact me before return. If item have defect within 2 months, we will send a replacement without extra charger.
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Christmas Jumper DayPublished on Friday 18th December 2015
A brilliant effort today raising lots of money for Text Santa!. We wish everyone a Merry Christmas and Happy New Year.
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We were delighted to welcome back to Meadowhead last year's A Level students and their families for a special presentation in the Rosling.
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This week there is a fantastic exhibition of creative work by Meadowhead staff and students in a professional gallery space....
Fashion Show reportPublished on Tuesday 8th December 2015
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Chitosan based wound dressing materials
The invention disclosed is a surgical dressing, particularly useful for the protection of wounds during the healing process. The dressing comprises a blend of gelatin and chitosan in a weight ratio of about 3:1 to 1:3 and a compatible plasticizer in an amount of 0-40% w/w based on the combined weight of gelatin and chitosan.
This invention relates to surgical dressings for covering wounds, lesions or the like, in the form of a continuous wound-adherent film which protects the wound during the healing process, and in particular to a wound dressing material comprising gelatin and a polymer which includes (free) amine groups available for complexing (cross-linking) with gelatin.
One such polymer is chitosan. Chitosan is a cationic biopolymer formed by deacetylation of the polysaccharide chitin, which is the main structural component of the exoskeleton of insects, spiders and crustaceans.
Because the cost of isolating chitin from the giant piles of shrimp, lobster, and crab shells discarded by shellfish processors is not excessive, there has been great interest in developing commercial uses for this biopolymer; many important applications for chitin and chitosan have been found already in fields such as waste water clarification, animal nutrition, and medicine. The vigor of the hydrolysis conditions used by the manufacturer in the conversion of chitin to chitosan determines the molecular weight of the chitosan. One indication of molecular weight is the viscosity of a solution of the material. One North American manufacturer, Bioshell Incorporated of Albany, Oreg., measures the Brookfield viscosity of a 1% solution in 1% aqueous acetic acid at 25.degree. C. and defines a high viscosity grade as 700-1000 cp, a medium viscosity grade as 250-650 cp, and a low viscosity grade as <250 cp.
The gelatin employed may be obtained from various sources such as bovine ossein, bovine skin, and pig skin, and be in a Bloom # range of 80-350.
A very large number of people are seriously burned in domestic and industrial accidents every year, and the number of these victims which dies in spite of intensive medical care is distressingly high. In Canada, the number of burn injuries requiring hospital admission approaches 25,000 per year. In the United States, about 130,000 are hospitalized annually because of burns; of these, 70,000 require intensive care at a cost exceeding $300,000,000, and 10,000 die.
The problem of burn treatment is even more acute in areas of the world in which there is armed conflict, since many of the weapons of modern warfare either directly or indirectly cause burns to both military personnel and civilians. In time of war the demands on medical facilities and supplies are very severe, and the mortality rate among burn victims is greatly increased.
In a third degree burn, the full thickness of the skin has been destroyed. The complete absence of "skin" cells in the burned area means that a new covering of skin will not spontaneously form there except by the very slow proliferation of healthy cells at the edges of the burn. One treatment is to remove a thin sheet of healthy skin from the patient's own body and graft it on the burned area. Only a partial thickness of skin is removed, so that the cells in the remaining layer of skin can regenerate a full thickness in the area from which the graft was harvested. In cases of burns covering 50% or more of the body surface area, this grafting procedure will be a lengthy process carried out in several stages because of the time required for regeneration of skin on the harvested sites.
In the intervening period between hospitalization and grafting, two very serious problems are caused by the absence of skin in the area of the burn. One of the most important functions of normal skin is to restrict the loss of body water by evaporation. The dramatic increase in water loss caused by destruction of the skin produces a large rate of heat loss due to the cooling effect of evaporation. In order to maintain a normal body temperature, the metabolic rate must increase, and a rapid depletion of fat and protein reserves ensues. The other serious problem caused by the absence of skin is bacterial invasion. If this invasive infection is not restricted, the high bacteria population makes the wound unsuitable for skin grafting. The victim of a major burn who receives no treatment for this infection will ultimately die from it.
After removal of the layer of dead tissue (eschar) lying on top of the burned area, it is desirable to cover the wound with a dressing which will control water loss and assist the body's own defences in controlling bacterial proliferation until skin grafting can be carried out.
Two natural materials, pig skin and human skin from cadavers, are regarded as very effective burn dressings. These materials can, under favourable circumstances, adhere to the wound very well and effectively control water loss and infection. One problem is that the body may recognize these biological materials as foreign substances, and begin a cellular response to reject them. Because of this, these biological dressings are usually replaced every 2 to 5 days. Another major drawback of these materials is their high cost. Cadaver skin at $80. and up per square foot, and pig skin at about $30. per square foot, are so expensive that physicians can be reluctant to use them except in cases in which they are essential for survival of the patient.
The disadvantages associated with these biological materials has given rise to the preparation of a large number of synthetic substitutes. The more effective of these have consisted of a foam, velour, or fibrious mat laminated to a synthetic resin film. Adhesion to the wound occurs by growth of tissue into the interstices of the foam or fibres, and the film controls loss of body water and prevents entry of bacteria. This basic approach has some inherent drawbacks. Since the adhesion depends on ingrowth, some time must elapse before the dressing is firmly adherent to the wound, and for this reason the pressing is usually secured to the wound with pressure dressings, sutures, or staples. A more serious problem in many cases has been the tenacious adherence that eventually does take place. Removal of the dressing can then be a traumatic procedure which may produce excessive bleeding and leave fragments of the synthetic material in the wound. These fragments may delay the healing of the wound when skin grafting is carried out.
A commercial laminate of this type with the trademark Biobrane is manufactured by Woodroof Laboratories, Inc. It is a composite of a flexible nylon fabric and an ultra-thin silicone rubber membrane. Although expensive (U.S. $40-50 per square foot), it is very effective on many types of open wounds such as granulation tissue, doner sites, and debrided second degree burns. Like most biological dressings such as pig skin, however, it performs relatively poorly on subcutaneous fat. This is unfortunate because early excision of third degree burn injuries usually exposes subcutaneous fat. Granulation tissue eventually does replace the fat, but there is a need in the intervening period for an effective, adherent wound covering.
A radically different type of burn dressing has been developed by I. V. Yannas and J. F. Burke and co-workers in the United States. Their approach has been to produce a material which slowly biodegrades at the wound surface and is assimilated by the body. During this biodegradation, the dressing not only restricts water loss and controls infections, but also acts as a tissue culture medium. Ultimately, migration of epidermal cells forms a new skin over the wound site. At the present state of development of their film, the healing of only relatively small wounds by this elegant process is possible. The film can be used to advantage on large wounds, but skin grafting is still required at a later stage. A commercial form of the film, when available, will probably be quite expensive.
Other useful wound dressings are described in applicant's co-pending Canadian applications Ser. No. 385,860 of Sept. 14, 1981, and Ser. No. 404,843 of June 10, 1982.
According to the present invention, a novel wound dressing material is contemplated, comprising a blend of gelatin and chitosan in a weight ratio of about 3:1 to 1:3, and a compatible plasticizer in an amount of 0-40% w/w based on the combined weight of gelatin and chitosan. In contrast to conventional wound dressing materials, this contemplated material displays excellent adhesion to subcutaneous fat.
According to another aspect of the invention, a novel method for making a wound dressing material is also contemplated, said material comprising gelatin and chitosan in a weight ratio of about 3:1 to 1:3, the method comprising
(a) dissolving the chitosan in water in the presence of a suitable acid resulting in a pH in solution of about 2-5,
(b) adding the gelatin dissolved in water, and
(c) mixing.
In order to combine chitosan with a water soluble polymer such as gelatin, the chitosan should be dissolved in water. Chitosan will sufficiently dissolve in water if acid is added. Both organic and inorganic acids have been found to be satisfactory for preparing chitosan solutions suitable for use in the present invention. Examples of acceptable organic acids are acetic acid, formic acid and lactic acid. Acetic acid is not a preferred acid because it imparts an odour to the resulting films. An example of a acceptable inorganic acid is hydrochloric acid (HCl). Chitosan has been found to be insufficiently soluble in certain organic and inorganic polybasic acids, such as citric acid and phosphoric acid, for them to be useful.
It is important that a minimal amount of acid be used in the preparation of the chitosan solution so that
(i) there will be as little acid as possible to neutralize in the final solution of chitosan and gelatin, and
(ii) there will be minimal degradation of the chitosan during the dissolving process.
This is done by adding the acid in small portions over a period of one or more hours to a stirred suspension of the chitosan in water at about room temperature. The resulting solution, if prepared from commercial chitosan, may contain numerous gel particles (partially hydrolyzed chitin) and insoluble material (mainly chitin) which can be removed by filtration. The dry weight of the insoluble material can be of the order of 10% of the original dry weight of the chitosan.
After mixing the acidic chitosan solution with gelatin dissolved in distilled water, the pH is often less than 5. (i.e. about 2-5) Although a continuous wound-adherent film prepared by casting this solution of a flat plate and allowing it to dry is a useful burn dressing, it is desirable to raise the pH in order to minimize the possibility that the film will cause pain or tissue damage when applied to the wound. Direct addition of 5% aqueous sodium hydroxide or 5% aqueous ammonia causes precipitation of a gel. Much more dilute solutions of these bases might not cause precipitation, but they would cause too great a dilution of the gelatin/chitosan solution. It has been found that a satisfactory basic solution for raising the pH is 5% aqueous sodium bicarbonate. Another method which has been used to raise the pH is the basification of the gelatin solution before addition to the chitosan solution. Achieving pH values much greater than about 6.3 is not possible because of precipitation of the chitosan or a chitosan/gelatin complex. If the original chitosan solution is dissolved in hydrochloric acid, gelatin/chitosan (1:1 by weight) films prepared by casting solutions adjusted to pH 6.3 are often cloudy or develop white areas if subjected to light pressure such as when held between thumb and forefinger. This problem is greatly diminished when lactic acid is used in place of hydrochloric acid for dissolving the chitosan, and when a lower pH, such as 5.7, is used.
The data in Table I show that pH has little effect on flexibility in the range 4.3-6.3. The flexibility test used for these measurements was described in detail on page 14 of our Canadian Patent Application Ser. No. 385,860 filed Sept. 14, 1981. Unplasticized gelatin/chitosan films are relatively stiff. The data in Table II shows the improvement given by the addition of compatible plasticizers such as glycerol and sorbitol. Both are effective plasticizers. The sorbitol modified films are clearly less flexible.
TABLE I ______________________________________ Effect of pH on the flexibility of gelatin/chitosan films. Weight required Gelatin.sup.2 : pH of gel- to force 15 mm Chitosan.sup.3 atin/chitosan Thickness wide sample Batch (parts by solution when of film sam- through a #1 weight) cast.sup.4 ple (mm).sup.5 6.5 mm gap..sup.6 ______________________________________ 229 1:1 4.3 0.061-0.064 21.6 g 229 1:1 4.8 0.068-0.069 26.0 g 229 1:1 6.3 0.065-0.069 26.0 g 230A 1:1 5.7 0.065-0.068 23.2 g 230A 1:1 6.3 0.062-0.066 20.6 g 230B 1:2 5.7 0.049-0.050 8.8 g 230B 1:2 6.3 0.050-0.052 10.2 g ______________________________________ Notes: .sup.1 Films with the same batch number were prepared using the same gelatin/chitosan solution. .sup.2 Ossein gelatin of Bloom #250. .sup.3 Chitosan of viscosity grade 970 cp. .sup.4 Hydrochloric acid was used to prepare the original chitosan solution; pH adjustment of the final gelatin/chitosan solution was done with 5% aqueous sodium bicarbonate. .sup.5 Range for several measurements in the central area of the film. .sup.6 Film strips were equilibrated at 35 .+-. 1% relative humidity at 2 .+-. 1.degree. C. for 24 hours before the measurements which were made under the same conditions. The test is described in detail on page 14 of commonly assigned copending a pplication Serial No. 406,523 filed August 9, 1982.
TABLE II __________________________________________________________________________ Flexibility and swelling properties of gelatin/chitosan films plasticized with glycerol and sorbitol. Gelatin/chitosan solutions were adjusted to pH 6.3 with 5% aqueous NaHCO.sub.3 before they were cast and dried. Parts by weight gelatin Weight required to (Bloom #), chitosan (vis- force 15 mm wide % Increase in length cosity), and plasticizer; sample through a 6.5 when swollen in Batch acid used to dissolve mm gap.sup.2 ; dry thick- distilled water.sup.4 ; #.sup.1 chitosan ness.sup.3 dry thickness.sup.5 __________________________________________________________________________ 235 15 gelatin (250), 27.4 g; 67%; 7 chitosan (630 cp), 0.078-0.084 mm 0.080-0.083 mm 0 plasticizer; HCl 235 15 gelatin (250), 11.4 g; 77%; 7 chitosan (630 cp), 0.080-0.085 mm 0.080-0.083 mm 2.2 glycerol, HCl 235 15 gelatin (250), 2.7 g; 77%; 7 chitosan (630 cp), 0.085-0.089 mm 0.085-0.087 mm 4.4 glycerol; HCl 235 15 gelatin (250), 0.8 g; 90%; 7 chitosan (630 cp), 0.094-0.099 mm 0.085-0.090 mm 6.6 glycerol; HCl 235 15 gelatin (250), 4.1 g; 97%; 7 chitosan (630 cp), 0.086-0.089 mm 0.085-0.088 mm 6.6 sorbitol; HCl 234 10 gelatin (250), 37.8 g; 124% 9 chitosan (130 cp), 0.094-0.097 mm 0.091-0.093 mm 0 plasticizer; HCl 234 10 gelatin (250), 19.4 g; 138%; 9 chitosan (130 cp), 0.092-0.096 mm 0.097-0.099 mm 2 glycerol; HCl 234 10 gelatin (250), 24.8 g; 121%; 9 chitosan (130 cp), 0.089-0.090 mm 0.093-0.096 mm 2 sorbitol; HCl 233 10 gelatin (250), 81.8 g; 67%; 9 chitosan (630 cp), 0.116-0.120 mm 0.112-0.115 mm 0 plasticizer; HCl 233 10 gelatin (250), 48.6 g; 66%; 9 chitosan (630 cp), 0.121-0.122 mm 0.122-0.125 mm 2 glycerol; HCl 233 10 gelatin (250), 55.4 g; 76%; 9 chitosan (630 cp), 0.120-0.123 mm 0.119-0.122 mm 2 sorbitol; HCl 236 10 gelatin (250), 109.0 g; 90%; 9 chitosan (630 cp), 0.138-0.149 mm 0.140-0.143 mm 0 plasticizer; lactic acid 236 10 gelatin (250), 23.2 g; 100%; 9 chitosan (630 cp), 0.124-0.132 mm 0.130-0.133 mm 2 glycerol; lactic acid 236 10 gelatin (250), 3.4 g; 90%; 9 chitosan (630 cp), 0.148-0.153 mm 0.133-0.138 mm 4 glycerol; lactic acid __________________________________________________________________________ Notes: .sup.1 Films with the same batch number were prepared using the same gelatin/chitosan solution. .sup.2 Film strips were equilibrated at 51 .+-. 2% relative humidity and 24.degree. C. for 13 hours (first 11 entries in table), or at 55 .+-. 2% relative humidity and 25-27.degree. C. for 12.5 hours (last 3 entries), before the measurements, whic h were made under the same conditions. The test is described in detail on page 14 of (our) Canadian Application Serial No. 385,860 filed 14 September. .sup.3 Range for several measurements in the central area of the film. .sup.4 Film strips 15 .times. 30 mm of the stated dry thickness were gently agitated in 50 ml of distilled water at room temperature for 1 hour. .sup.5 Range for several measurements over the entire film area.
Although gelatin/chitosan films transmit water vapour very well, they will still swell a great deal when placed on wounds which are very moist because of rapid exudate production. However, they do have the very desirable property of swelling much more in thickness than in length and width. Because swelling in length and width places a shear stress on the adhesion of the film to the wound, it is important that swelling in these dimensions be as small as possible. A relative indication of the degree of swelling that a film may undergo when exposed to copious quantities of wound exudate is given by its swelling when immersed in distilled water. The last column of Table II shows that the presence of substantial amounts of glycerol and sorbitol do not have a large affect on the increase in length as a result of immersion in distilled water. It is thus contemplated that 0-40% w/w, preferably about 21% w/w of the plasticizer, based on the combined weights of gelatin and chitosan, can be usefully added.
Several of the films in Table II were prepared with chitosan of viscosity grade 130 cp. These films produced weak hydrogels when swollen in water, in contrast to the hydrogels from the viscosity grade 630 cp chitosan which were relatively strong. For this reason, viscosity grades in the range 150-1100 cp are contemplated. However a viscosity grade of about 500 cp is preferred.
It has been found that, on fresh excisions down to subcutaneous fat on the back of a juvenile domestic pig, some gelatin/chitosan films actually contract slightly, shortly after application. The results of tests on six different gelatin/chitosan preformed films are given in Table III. It was found that the presence of glycerol increased shrinkage. Use of lactic acid to dissolve chitosan caused more shrinkage than use of hydrochloric acid. Hydrochloric acid is thus preferred.
TABLE III ______________________________________ Shrinkage of gelatin/chitosan films on freshly excised wounds down to subcutaneous fat on the back of a juvenile domestic pig. Film.sup.1 Length, to nearest 0.5 Parts by weight of each mm, of film strips 40 mm component; acid used to long after 0.5 hr. and dissolve chitosan; thick- Film Sample 4.0 hr. on the wound ness # 0.5 hr. 4.0 hr. ______________________________________ 10 gelatin, 1 40.5 40.5 9 chitosan; 2 40 40 HCl; 0.11 mm 10 gelatin, 1 39 39 9 chitosan; 2 39 39 lactic acid; 0.11 mm 15 gelatin, 1 39 39 7 chitosan; 2 38.5 38.5 HCl; 0.08 mm 15 gelatin, 1 .sup. 37.sup.2 37 7 chitosan, 2 .sup. 38.sup.3 38 6.6 glycerol; HCl; 0.09 mm 10 gelatin, 1 .sup. 38.sup.2 38 9 chitosan, 2 .sup. 38.5.sup.2 38 4 glycerol; lactic acid., 0.14 mm 10 gelatin, 1 .sup. 38.5.sup.2 38 9 chitosan, 2 39 38.5 6 glycerol; HCl; 0.13 mm ______________________________________ Notes: .sup.1 Cattle ossein gelatin, Bloom #250, was used. The chitosan was viscosity grade 630 cp. All films were prepared from solutions adjusted t pH 6.3 before casting. .sup.2 Top surface of film was slightly tacky. .sup.3 Top surface of film was tacky.
The effects of film composition on adhesion to subcutaneous fat was determined by placing films on freshly excised wounds down to about the middle of the top fat layer on the backs of juvenile domestic pigs. The films are not secured to the wounds by any means other than natural adhesion, and no other dressing was placed on top. The degree of adhesion was assessed subjectively immediately after placement on the wound, at three or four days, and at seven days. The results are given in Table IV. The performance of all film compositions was generally satisfactory. The relatively poor result in entry #4 was anomalous since the same film in entry #3 did extremely well on another site. Over the seven day period there was a gradual loss of adhesion at the edges of the wounds. A thick, crusty exudate developed in the gap between the edge of the film and the edge of the wound, and the growth of the exudate and granulation tissue in this gap contributed to the dislodgement of the film at the periphery. In addition, forces caused by the animals' movements which tend to disrupt the adhesion will be greater at the edges than at the centre. Hospitalized burn patients would be much less active and may in fact have the affected areas immobilized; under clinical conditions, therefore, disruption of adhesion will be much less likely.
Removal of adherent wound dressings can be very traumatic in terms of pain for the patient and damage to the wound bed. Although the gelatin/chitosan films normally exhibit a strong adhesion to the wound, this adhesion is lost when the films are converted to the hydrogel by swelling in water or physiological saline solution. For example, after seven days of continuous adhesion to the wounds, the films in entries #2, #3, #8, and #9 in Table IV were soaked in physiological saline for ten minutes. At the end of this time all of the films had little or no adhesion to the wound, and could be easily pulled off as intact sheets.
TABLE IV ______________________________________ Adhesion of various formulations of gelatin/chitosan films to freshly excised wounds down to the middle of the top layer of fat on the backs of juvenile domestic pigs. Film.sup.1 Parts by weight of each Subjective assessment of component; acid used to adhesion of film to wound; area Entry dissolve chitosan; thick- of wound to which adhesion # ness had been maintained. ______________________________________ 1 5 gelatin, 0 days: excellent 7 chitosan (630 cp); 3 days: excellent; 90% HCl; 0.08 mm 7 days: excellent; 75% 2 1 gelatin, 0 days: fair-good 1 chitosan (970 cp); 4 days: very good; 65% HCl; 0.06 mm 7 days: very good; 30% 3 10 gelatin, 0 days: good 9 chitosan (630 cp); 4 days: very good; 90% HCl; 0.12 mm 7 days: very good; 80% 4 10 gelatin, 0 days: very good in centre, 9 chitosan (630 cp); poor at corners HCl; 0.12 mm 3 days: fair; 5%; film removed 5 10 gelatin, 0 days: excellent in centre; 9 chitosan (630 cp); poor at corners lactic acid; 0.14 mm 3 days: excellent; 50%; film removed 6 10 gelatin, 0 days: excellent 9 chitosan (630 cp), 4 days: very good; 80% 4 glycerol; 7 days: excellent; 50% HCl; 0.12 mm 7 10 gelatin, 0 days: excellent 9 chitosan (630 cp), 3 days: excellent; 90% 4 glycerol; 7 days: excellent; 75% lactic acid; 0.14 mm 8 10 gelatin 0 days: excellent 9 chitosan (630 cp), 4 days: very good; 75% 6 glycerol; 7 days: very good; 50% HCl; 0.13 mm 9 15 gelatin, 0 days: good 7 chitosan (630 cp), 4 days: very good; 75% 6.6 glycerol; 7 days: good; 60% HCl; 0.09 mm ______________________________________ Notes: .sup.1 Cattle ossein gelatin, Bloom #250, was used. All films were prepared from solutions adjusted to pH 6.3 before casting.
Although wound contraction is a normal part of the healing process, in the severely burned patient it can lead to rigid scars which, in addition to causing disfigurement, can produce a crippling loss of normal motion. Gelatin/chitosan films have the ability to retard contraction. This is shown in Table V, in which the product of the wound length and width at eight days is compared with that when the dressings were initially applied. The ratio for the site which had the control film of vaseline gauze was 23-45% lower than that of the three sites which had the gelatin/chitosan film.
TABLE V __________________________________________________________________________ Inhibition of contraction of a freshly excised wound down to subcutaneous fat.sup.1 by a gelatin/chitosan film over a period of 8 days. Wound Dressing Observation at 8 days ##STR1## __________________________________________________________________________ vaseline gauze.sup.2 Healthy granulation tissue had formed ##STR2## gelatin/chitosan.sup.3 Film remained adherent to 80% of original area; adhesion excellent. ##STR3## gelatin/chitosan.sup.3 Film remained adherent to 70% of original area; adhesion excellent. ##STR4## gelatin/chitosan.sup.3 Film remained adherent to 50% of original area; adhesion very good. ##STR5## __________________________________________________________________________ Notes: .sup.1 Middle of the top fat layer on the back of a juvenile domestic pig .sup.2 Control dressing of Bactigras .RTM. (Smith and Nephew, Incorporated, Lachine, Quebec). It was replaced with fresh Bactigras at 4 days. .sup.3 Film was a 1:1 mixture of cattle hide gelatin of Bloom #150 and chitosan of viscosity grade 970 cp. The gelatin/chitosan solution was adjusted to pH 4.8 just before it was cast. Thickness was 0.08 mm. .sup.4 Length is defined as parallel to the spine and width as perpendicular to the spine. Measurements were made in the centre of the wound from hairline to hairline.
Instead of allowing a layer of gelatin/chitosan solution to dry to a film of a flat plate and then applying that preformed film to a wound, there are advantages to direct coating of the gelatin/chitosan solution on a wound and letting it dry to a film in situ. Because a liquid can flow into depressions and crevices, there are no air spaces left to become filled with exudate and possibly be converted to sites of localized infection. In addition, the larger area of contact as compared with application of a preformed film can produce a superior overall adhesion. Unfortunately, the gelatin/chitosan solutions used to prepare the films dry too slowly, and they do not form gels on the wound soon after application but remain as viscous liquids until close to dryness. A method has been discovered for producing a tough outer gel layer on the top of the freshly applied gelatin/chitosan liquid coating. This consists of adding a solution of a setting agent, which may be the salt of a polyvalent cation which can crosslink the polymers by forming bonds to anionic sites, or a basic solution which can raise the pH of the liquid, thereby causing formation of a gel of chitosan or of a complex of chitosan and gelatin. Many basic agents can be used. However, those which would give solutions which are highly caustic should be avoided because of the hazard of accidental contact with healthy tissue. Examples include NaOH, NH.sub.3 and Na.sub.2 CO.sub.3. Two setting agents which have proven very effective are zinc acetate and sodium bicarbonate. The preferred method of application of these setting agents is to soak an absorbent, flat pad of paper or cloth with an aqueous solution and lay it on the freshly applied gelatin/chitosan liquid for about one minute; the pad can then be easily removed. The newly formed outer layer of gel on the surface of the gelatin/chitosan film is strong and only slightly tacky if at all. Beneath this gel there is a relatively mobile layer of gelatin/chitosan liquid. The outer gel layer and inner liquid layer eventually dry to a single, strong, transparent film. Preferred concentrations of zinc acetate and sodium bicarbonate are 2.5%/w and 9%/w respectively. When sodium bicarbonate or other suitable base is used, the pH of the gelatin/chitosan liquid applied to the wound should be close to the upper limit at which the polymers remain in solution, i.e. 6.0 to 6.3, preferably about 6.3. When no setting agent or when zinc acetate is used a pH range of 4.0-6.3 is envisaged.
Although use of a pad soaked in a solution of a setting agent is preferred, other methods can be envisaged, such as spraying a fine mist of the solution on the liquid or applying the setting agent as a dry powder by shaking or spraying. A successful procedure used in initial experiments consisted of placing drops of the setting agent solutions directly on the liquid and then gently "patting" them by hand to spread them out.
Tests of a liquid composed of 10 parts gelatin (ossein; Bloom #250), 9 parts chitosan (viscosity grade 630 cp; dissolved with hydrochloric acid), 4 parts glycerol, and 470 parts water, and adjusted to pH 6.3, were carried out on fresh excised wounds down to the top layer of subcutaneous fat on the backs of juvenile domestic pigs. On two sites the liquid was applied alone; no setting agent was used. Drying of the film was almost complete after one hour. When examined after seven days, the film had a few long cracks with gaps between the broken edges. These cracks may have been due to contraction of the film during drying. The adhesion to the wound, assessed subjectively, ranged from very good to excellent. The film was left on one of the sites for an additional three days, after which it still had very good adhesion. On a third site, the same liquid was set with an aqueous solution of zinc acetate. After seven days, the film was not cracked, and had excellent adhesion to 75% of the original wound area.EXAMPLE 1
Sixteen grams of chitosan (from Bioshell, Incorporated; Lot 2200; viscosity grade 630 cp) were suspended in 750 ml of distilled water and stirred at about 60 rpm at room temperature with a motor driven rod fitted with three impellers 72 mm in diameter. About one ml of concentrated hydrochloric acid was added dropwise to the stirred mixture over a period of one minute. After ten minutes, another one ml was added dropwise. This was repeated at 10 to 15 minute intervals until a total of 7 additions (7 ml or about 3.1 grams of hydrochloric acid) had been made. The initial pH of the suspension was 5.8. Ten to fifteen minutes after the addition of each of the first six 1 ml portions of concentrated hydrochloric acid, the pH was 4.5 to 5.0. Twenty minutes after the final addition, it was 2.3. After another 60 minutes, it had risen to 3.0. At this point there were still swollen, transparent gel particles and white flakes left in the viscous solution.
Sixteen grams of cattle ossein gelatin (Knox Brand; Thomas J. Lipton Company; Bloom #250) were dissolved in 90 ml of distilled water at about 50.degree. C. The warm gelatin solution was added to the chitosan solution prepared above and the mixture was stirred for 30 minutes. At the end of this time the pH was 4.8. A 5% aqueous solution of sodium bicarbonate was added dropwise with stirring in portions of about 5 ml over a period of approximately 2 hours until the pH had risen to 5.7. A total of about 43 ml or 2.2 grams of sodum bicarbonate was required. A solution of 6.4 grams of glycerol in 20 ml of distilled water was added, and the mixture was stirred for 15 minutes. The solution was filtered through a 70 mesh polyester screen using mild suction to remove insoluble material present in the original chitosan solution. When dry, the residue from the filtration weighed 3.1 grams. The viscous liquid left a thick film on the inside of the containers when it was poured out. The losses of viscous solution as a thick residual film on the filtration apparatus and filter left only 550 ml of filtrate. This filtrate was too viscous for the bubbles to rise to the surface in a reasonable length of time. A satisfactory viscosity was achieved by dilution with 100 ml of distilled water. The solution was cast on a sheet of polystyrene to dry in the normal room atmosphere. The dry film removed from the sheet after 7 days had a thickness of about 0.1 mm and was transparent except for a faint, cloudy ring near the periphery.EXAMPLE 2
(Illustrating a single addition of hydrochloric acid, which is not preferred, and the elevation of pH by the addition of a basified gelatin solution, which is also not preferred.)
Four grams of chitosan flakes (from Bioshell, Incorporated; Lot 2065; 970 cp) were stirred at room temperature with a solution of 1.75 g of concentrated hydrochloric acid in 200 ml of distilled water for 11 hours and then left overnight. Some insoluble material was removed from the viscous solution by means of a pipette having a large opening. The solution, whose pH was 1.8, was warmed to about 30.degree. C. prior to mixing with the gelatin solution described below. A solution of 4 g of gelatin (retail grade, Davis Gelatine Company; hide gelatin; Bloom #150) in 80 ml of distilled water was prepared and, while at about 30.degree. C., its pH was raised to 9.8 by the addition of aqueous sodium hydroxide. Within minutes of adjustment to pH 9.8, the warm gelatin solution was added in portions with vigorous stirring to the warm chitosan solution. Stirring was continued for 7 minutes after completion of the addition. At the end of this time the homogenous mixture had a pH of 4.8. The film obtained after casting this solution and drying at ambient temperature and humidity had a thickness of 0.09 mm and was slightly hazy.EXAMPLE 3
A suspension of 15.5 grams of chitosan (from Bioshell, Incorporated; Lot 2200; viscosity grade 630 cp) in 750 ml of distilled water was stirred as in Example 1 at room temperature while 1.0 ml of 88% aqueous lactic acid solution (Fisher Scientific; Product #A-162; mixture of D-lactic acid and L-lactic acid) was added dropwise. At intervals of 5 to 10 minutes, another 4 portions of 1 ml were added dropwise, followed by 2 portions of 0.5 ml each. Twenty minutes after the final addition of 0.5 ml, the pH was 4.5. In order to remove undissolved material, the very viscous solution was filtered through a J-Cloth.RTM. towel (Johnson and Johnson; medium; #1633), which had previously been washed with distilled water. When dry, the insoluble material weighed 1.92 grams. The filtrate was warmed in preparation for addition of the gelatin solution described below.
Fifteen grams of gelatin (Knox Brand; Thomas J. Lipton Company; cattle ossein; Bloom #250) were dissolved in 60 ml of distilled water by warming. The warm solution was added to the warm chitosan solution. After thorough mixing, the pH was 4.8. Stirring was continued as a total of 35 ml of 5% aqueous sodium bicarbonate was added dropwise in portions of 2-5 ml; a period of 10 minutes was allowed between each portion. Ten minutes after completion of the final addition, the pH was 6.3.
Six grams of glycerol in 30 ml of distilled water were added. The mixture was stirred and then allowed to stand in a warm bath (30.degree.-45.degree. C.), for 5.5 hours in order for the majority of small bubbles to rise to the surface. The foam on top was then skimmed off and the solution, whose temperature was 36.degree. C., was cast onto a polystyrene sheet and left to dry at ambient temperature and relative humidity. After 4 days, the dry film was removed from the plate; its thickness was 0.14 mm.EXAMPLE 4 (Liquid)
A suspension of 18 grams of chitosan (from Bioshell, Incorporated; Lot 2200; 630 cp) in 750 ml of distilled water were stirred as in Example 1 and 1.0 ml of concentrated hydrochloric acid was added dropwise. Another 5 one ml portions of concentrated hydrochloric acid were added at intervals of 5-15 minutes. Thirty minutes after the addition of the final portion, the pH was 4.2. The mixture was allowed to stand for 45 minutes, and then was stirred for 15 minutes. At the end of this time the pH was 4.8. The very viscous solution was filtered by gravity through a piece of 70 mesh polyester sieve cloth. After the insoluble material had dried, it weighed 2.1 grams. The filtrate was warmed for the addition of the gelatin solution described below.
Eighteen grams of gelatin (Knox Brand; Thomas J. Lipton Company; ossein gelatin; Bloom #250) were dissolved in 60 ml of warm distilled water. The warm gelatin solution was mixed with the warm chitosan solution, and the pH of the mixture was raised from 4.8 to 6.3 by the addition of a total of 48 ml of 5% aqueous sodium bicarbonate dropwise in portions of 3-10 ml added at intervals of 5-10 minutes.
A solution of 7.2 grams of glycerol in 15 ml of distilled water was added and the mixture was stirred for about 15 minutes. It was allowed to stand in a warm bath to allow the bubbles to rise to the surface where they were skimmed off.
The solution is stored at about 4.degree. C. At this temperature it sets to a gel which must be melted by gentle warming before use.
1. A method for making a wound dressing material, said material comprising a blend of gelatin and chitosan in a weight ratio of about 3:1 to 1:3, the method comprising:
- (a) dissolving the chitosan in distilled water by adding lactic acid or hydrochloric acid in small portions over an extended time period to a stirred suspension of chitosan in water at about room temperature, the acid resulting in a pH in solution of about 2-5,
- (b) adding the gelatin dissolved in dissolved water,
- (c) mixing, and
- (d) adding a basic solution to raise the pH of the mixture so formed to about 5.7 to 6.3.
2. A method according to claim 1, wherein the basic solution is 5% aqueous sodium bicarbonate.
3. A method according to claim 2, including the additional step of (e) adding a compatible plasticizer selected from the group consisting of glycerol and sorbitol.
4. A method according to claim 3, including the additional step of
- (f) casting the solution on a flat plate and drying to a continuous wound-adherent film.
5. A method according to claim 3, including the additional step of
- (f) coating the solution onto a wound and drying in situ.
6. A method according to claim 5, which includes the additional step of
- (g) apply a solution of a non-caustic setting agent onto the freshly applied coating to provide a tough outer gel layer.
7. A method according to claim 6, wherein the setting agent is selected from zinc acetate and sodium bicarbonate.
8. A method of treating a wound which comprises applying to the wound a wound dressing material in the form of a continuous preformed film, the material comprising a blend of gelatin and chitosan in a weight ratio of about 3:1 to 1:3 and a compatible plasticizer in an amount of 0-40% w/w based on the combined weight of gelatin and chitosan.
9. The method according to claim 8, wherein the weight ratio of gelatin to chitosan is about 1:1.
10. The method according to claim 9, wherein the plasticizer is selected from the group consisting of glycerol and sorbitol.
11. The method according to claim 8, wherein the chitosan is of a viscosity grade of about 630 cp and the gelatin has a bloom number of about 80 to about 350.
12. A method of treating a wound which comprises
- (1) applying to the wound a coating of an aqueous solution of a burn dressing material comprising a blend of gelatin and chitosan in a weight ratio of about 3:1 to 1:3 and a compatible plasticizer in an amount of 0-40% w/w based on the combined weight of gelatin and chitosan, and allowing the thus applied coating to dry in situ; and
- (2) applying a solution of a non-toxic setting agent on to the freshly applied coating to provide a tough outer gel layer.
13. The method according to claim 12, wherein the setting agent is selected from zinc acetate and sodium bicarbonate.
14. The method according to claim 12, wherein the weight ratio of gelatin to chitosan is about 1:1.
15. The method according to claim 12, wherein the plasticizer is selected from the group consisting of gylcerol and sorbitol.
16. The method according to claim 12, wherein the chitosan is of a viscosity grade of about 630 cp and the gelatin has a bloom number of about 80 to about 350.
|December 1951
|February 1958
|Sullivan et al.
|September 1962
|Starck et al.
|January 1965
|January 1971
|August 1971
|January 1972
|October 1973
|September 1975
|October 1975
|October 1975
|January 6, 1981
|May 5, 1981
|Sugitachi et al.
|May 10, 1983
|October 2, 1984
Type: Grant
Filed: Oct 2, 1984
Date of Patent: Feb 25, 1986
Assignee: Her Majesty the Queen in right of Canada, as represented by the Minister of National Defence of Her Majesty's Canadian Government (Ottawa)
Inventors: Brian G. Sparkes (Toronto), Douglas G. Murray (Willowdale)
Primary Examiner: Theodore Morris
Law Firm: Cushman, Darby & Cushman
Application Number: 6/656,851
International Classification: A61F 1300; A61K 3700; A61K 3170; C09D 304;


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CBSE exams return: Schools, parents call decision 'regressive', seek review by MHRD
Schools and parents are opposed to the Central Board of Secondary Education's (CBSE) recent decision to increase weightage for the written test to 80% from 20% and introduce the three-language formula — which doesn't include any foreign language — for Class 10 exams.mumbai Updated: Dec 21, 2016 17:42 IST
Schools and parents are opposed to the Central Board of Secondary Education's (CBSE) recent decision to increase weightage for the written test to 80% from 20% and introduce the three-language formula — which doesn't include any foreign language — for Class 10 exams. The board had announced on Tuesday that the optional Class 10 exams will be made mandatory again from the next academic session, 2018.
As of now, schools carry out formative assessments — in the form of projects, activities and practical exams — throughout the year and the biannual summative exams — testing students on what they have learnt by the end of the semesters.
But now teachers are worried that increasing focus on the written exams at the end of the year will turn students into rote learners. The three -language formula — which will require schools to teach Hindi, English and another language listed in schedule VIII of the Constitution of India — will be tough on those studying foreign languages for the last several years, teachers said.
Calling the move regressive, teachers plan to write to the ministry of human resource development (MHRD) to reconsider its decision. "Students will go back to studying only for exams if we give too much importance to written exams," said Deepshika Srivastava, principal, Rajhans Vidyalaya, Andheri.
The CBSE's move has defeated the purpose of the compulsory comprehensive evaluation (CCE), which encouraged year-round assessments in various forms, Srivastava said, adding, "The formative assessments went beyond just testing the writing skills of students. It allowed us to test their multiple intelligences."
"If this is implemented by 2018, the current batch of Class 9 students will need to master one new language in less than a year," said Raj Aloni, principal of Ram Sheth Thakur Public School, Kharghar.
Parents complained that the three-language formula will force students to take up Sanskrit or a regional language. "It's going to be difficult for students who have probably taken French as their third language and will depend on how schools implement the change," said a parent from Podar International School (CBSE), Powai. Another parent added, "The CBSE can't force students to take up Sanskrit. We want students to opt for global languages, which will help them in their careers."
Want to study a foreign language at CBSE school? You may have to take 3 more


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April 10, 2012
Since December 2011, 60 community members have been trained in the Food Security and Nutrition (FSN) Training School for Community Change Agents of Tumaco. The participants are mothers, community members, college students and staff of community councils. They have expanded their leadership skills and built their capacity to participate at the same level as other institutional actors (with expertise in FNS) in the formulation of Municipal Public Policy in Food Security and Nutrition. Read more
January 16, 2012
On December 20th, Alexander Trofimov, an important Russian real estate investor, was released from Preah Sihanouk Provincial Prison after serving just over half of his sentence for sex crimes with 17 underage girls. Read more
January 16, 2012
The American Phillip Bruce Shepard has been convicted in Phnom Penh to 10 years in prison for paying two children, to whom he had adopted in 2004, in exchange for sex. Shephard will be deported after serving his sentence in Prey Sar prison. Read more


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Call The Inn at 301-432-6601 or click here to make a reservation.
Standard Rates for 2019:
Off Season (mid-December through March): $160/night plus tax
High Season (April through mid-December): $175/night plus tax
The tax rate is 12% (6% state, 6% county).
Please note: the Inn will be closed December 20, 2019-January 31, 2020.
Note, the pricing listed above is per night for single or double occupancy. Our rates do not include taxes, and are subject to change without notice. Rates include a plated breakfast each morning, complimentary Wi-Fi, and parking.
Of our four suites, three (Antietam, Capitol, and Edmonds) can accommodate additional guests. Additional guests rates are $25/child (18 years and younger) and $35/adult–per night. We also have twin blow-up mattress available that could be used in any of the suites.
Dog reservation fee is $35/reservation. If you do not have a crate and need one, we have one for complementary use. Dogs are allowed in the Antietam or Edmonds Suites only.
If you are traveling with small children and need a use our pak-n-play, we have one available for complementary use.
The following holiday weekends and special events are subject to a 2 night minimum stay:
Gift certificates are available, please contact us for information.


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Research residency at the Laboratory of Art and Water together with journalist and photographer Agnès Villette. The project is initiated by Esam Caen-Cherbourg (Art Academy) invited by Thierry Weyd, Professeur enseignement histoire et théorie, responsable de l'axe "Matière et matériau" du Laboratoire de l'art & de l'eau and Camille Prunet, Research Coordinator chez école supérieure d'arts & médias Caen/Cherbourg.
Find more information here as the project progress.
Find a video report for a project to restore the river L'Orne here. It is produced by the Agence de l'eau Seine-Normandie and CATER.
Will be recording and working by and in L'Orne by L'ENFERNAY (St Rémy) and l'usine LE CHAMEAU (Condé sur Noireau).
L'Orne seen in infrared:
Click here to return to the Field Trips page


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You can report improper conduct to one of the AUAS confidential advisers. They will assist you and register your complaint anonymously. Improper conduct includes but is not limited to discrimination, abuse, bullying, sexual harassment and verbal aggression.
You can also file a report on behalf of a colleague, fellow student or visitor, such as a supplier, temporary staffer or work placement student.


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Very Compassionate
I retained Mr. Doty for my divorce case. It was a very highly contested case with a lot on the line. He handled my divorce with attentiveness and compassion. I am very pleased with the end results. I will definitely retain him again in the future if I ever need an attorney.
- Ann


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Serve in Grove Kids ministry by helping in Sunday morning classes and creating fun spaces for kids to experience God's love.
Serving Opportunities
Filter By
Create a hospitable environment for guests, as well as, help facilitate meaningful worship experiences on Sunday mornings. This includes serving as a greeter, parking lot attendant, coffee service, ushering, etc.
Connect with new guests and help them find their place at The Grove.
Create memorable moments in the neighborhood by helping to organize and execute special events, such as movie nights, dinners, Easter egg hunts, etc.
Serve in Grove Groups by leading a group of people as they grow in their faith and in their life. Our groups range from Bible-study style groups to groups who go to dinner together and talk about sermons. This is an 8-12 week commitment. Whether you have a group of friends, or want to recruit new ones, we'd love to have you as a leader!


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Bubonic Plague Causes Chinese City
Taking precautionary measures to a whole new level, an entire Chinese town of over thirty thousand people was quarantined off from the rest of the country after a man from a nearby village died of bubonic plague. Although four people were also diagnosed with the very same disease in Colorado, during the same week, those were treated quickly and effectively in hospital and released, whereas Yumen's authorities opted for a far more dramatic response.
According to China Central Television, or CCTV, the thirty-eight year old farmer died of the disease after coming into contact with a dead marmot (a large, ground-based squirrel that is typically found within mountainous areas). Although nobody within the city is believed to have contracted the disease at this point, 151 individuals who might have come into contact with the man have been placed under direct observation, just in case.
The plague, otherwise known to many as 'The black death' is by far one of the oldest and most identifiable diseases known to mankind, after it left its infamous mark on our history books. For those who don't know, the disease is caused by contracting a bacterium known as Yersinia Pestis, which is capable of infecting various pests and animals such as prairie dogs, squirrels, and rats. This lethal bacterium can be transmitted to humans in one of the following ways:
- Contact with infected droplets or fluids coughed up by someone infected with the disease
- Flea bites from an animal with Y Pestis
Although many people remember one particular plague event most commonly, there have actually been three pandemics recorded in history, the first of which began in 541 AD and continued for approximately two hundred years, killing over one hundred million people in total. The most famous plague pandemic, The Black Death, occurred in the fourteenth century and wiped out around 60% of Europe's population, and the last pandemic in 1860 took place in China, killing around 10,000,000 people.
Although plague continues to be endemic throughout various areas in the world, and is most commonly found in Madagascar and Sub-Saharan Africa, it has also been known to occur in the United States. Between the years of 1900, and 2010, a total of 999 cases have been confirmed and recorded within America. Although it is still incredibly serious, and highly contagious if not treat with expert medical care, antibiotics can now effectively treat the disease, making it a lot less scary than it once was.


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Mark Hamill calls Trump's Cabinet 'a who's-who of really despicable people'
"Star Wars" actor Mark Hamill weighed in on President-elect Donald Trump saying he's in "total denial" over the election results.
"I'm glad I have [my new show 'Pop Culture Quest'] to take my mind off what's going on," Hamill told the Daily Beast. "Because if you look at what's being assembled for our government it's like, yikes. It's a who's-who of really despicable people."
Hamill did not mention any of Trump's appointments by name. Several Cabinet positions have been filled since he won the election earlier this month.
Hamill added that while it's "tempting to say" he'll leave the country under a President Trump, it's more challenging to "stay and defend our country and do what you think is right."
He continued, "And not to retreat and hide under the covers. It's not going to be easy, that's for sure."
The actor will reprise his role as Luke Skywalker in 2017's "Star Wars Episode VIII."


text: Meakawa River Camp (Shikoku). A free campsite at a beautiful spot along the river with forested hills on the opposite site. Cars have to stay in the parking lot (no shade) but that gives the same view as the campsite itself. Showers, toilets, and sinks for dishes. (July '17). gps: 33.924547 134.49642


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Simple hand woven Kenyan multi-purpose striped brown sisal basket.
Unique design and nicely done with open top for easy item reach. Great for picnics!
Good for toys, storage, towels or even magazines.
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Aster & Oak
Aster & Oak Garden Fairy Zip Romper
or make 4 interest-free payments of $8.75 AUD fortnightly with More info
This Zip Romper in the stunning Garden Fairy design is made from GOTS certified organic cottons & dyes, so is extremely soft and gentle on your little ones skin. This romper features fitted stretch cuffs, reinforced stitching, zipper covers for extra protection and a heavy duty, easy glide, 2 way zipper. This romper is photo ready when worn with the matching Garden Fairy or Berry Topknot headband.


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Dissension: War Eternal Vol 1 #4
- Publisher: Aspen Comics
- Writen By: Chrisopher Fielder Jordan Gunderson
- Art By: Jordan Gunderson
- Language: English
- Genre: Action/Adventure
- Digital Release Date: January, 16th, 2019
The origin of Delphi's precognitive powers becomes clearer and she and Pirate find themselves prisoners of the very government they are fighting so hard to protect. Lilith and her cohorts make their long-awaited return to Earth and the source of the power that gave them dominion over humanity so many centuries ago. From artist and creator Jordan Gunderson comes Aspen's most thrilling new series, DISSENSION: WAR ETERNAL!→ more