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UP #30: Redefining Activism and Living an Inspired Life with Roz Savage
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Imagine a world where an indescribably powerful beam of universal higher consciousness has completely altered the minds of humanity. This beam of higher consciousness has roused the pure potential of love, connection, and compassion previously dormant in the hearts of the masses.
People around the globe shake off the slumber from centuries of separation. Conformity, judgement, fear, selfishness, apathy, and indifference are replaced with authentic expression, acceptance, love, selflessness, passion, and inspiration. Kindness and community are restored.
Animals are no longer treated as commodities. Rather, they're remembered as the fellow earthlings that they've been all along. The mere thought of exploiting, oppressing, and consuming the bodies of innocent sentient beings triggers revulsion as this behavior finally makes its way to the history books of a primitive species that had lost its way.
A deep love for the natural world returns to the hearts of the masses. And the shocking planetary mess created by this once primitive species becomes the greatest priority for all to act on. Together – united as one team with the singular mission of healing planet earth.
Alright, now take a deep breath and let's return to reality.
There hasn't been a powerful beam of universal higher consciousness that has altered the minds of humanity, and separation is still the prevailing mindset, BUT, what if your thoughts, choices, and actions have a much greater impact on planetary healing than you could ever imagine? What if YOU are the powerful beam of universal higher consciousness that was imagined only a few moments ago?
What if everyone remembered that the powerful beam of universal higher consciousness already exists within their hearts?
If everyone remembered their essential nature and operated at their highest potential, what would the world look like?
When you turn up the volume on your own personal potential, how would your life change and how would the lives of everyone around you be impacted?
We often forget how inspiring we are when we operate from our core being. When we express ourselves authentically with our actions aligning with the truth of our essential nature, we really are the change that the world needs. Individual actions multiplied by many have the very real potential to heal this planet.
This is the topic of today's Unplug podcast interview.
Today we speak about how the powerful beam of universal higher consciousness snapped a former British management consultant out of her consumptive ways into the inspiring role of adventurer/passionate environmental advocate.
Roz Savage is the first woman to row solo 3 oceans – the Atlantic, Pacific, and Indian.
As she states on her website:
"She has rowed over 15,000 miles, taken around 5 million oarstrokes, and spent cumulatively over 500 days of her life at sea in a 23-foot rowboat. She uses her ocean rowing adventures to inspire action on the top environmental challenges facing the world today.
Since embarking on her first ocean in 2005, she has braved 20-foot waves, been capsized 3 times in 24 hours, and faced death by dehydration when both her watermakers broke. She has encountered whales, dolphins, sharks, and turtles, and admired the timeless beauty of sunrises, sunsets, and star-filled night skies. The ocean has forced her to develop courage, tenacity, perseverance, and the strength to transcend self-imposed limits."
Roz is the author of two books : "Rowing the Atlantic: Lessons Learned on the Open Ocean" and "Stop Drifting, Start Rowing: One Woman's Search for Happiness and Meaning Alone on the Pacific". I have to say, there are few books that leave me wanting more but "Stop Drifting, Start Rowing" was one of those books that could have easily continued on for a few more hundred pages.
Today Roz and I chat about:
• Living an inspired life that matters.
• How writing an imagined obituary changed the course of her life.
• How the ocean is regarded as a cross between a sewer and a garbage dump.
• The planetary scourge of plastic and how it has fundamentally altered the chemistry of the oceans.
• How we live in the ultimate closed-loop system on planet Earth. What goes around always comes around.
• The power of each individual action and how when multiplied by many, can heal the world.
• How we owe it to the collective evolution of humanity to live our lives as the best version of ourselves possible.
• How happiness and purpose go hand-in-hand.
• The important things in life aren't things.
• Redefining activism.
As Roz herself states:
"I believe that if you don't keep pushing the boundaries, keep expanding your comfort zone, your comfort zone actually gets smaller and smaller, until you're shrink-wrapped in such a tiny comfort zone that you can't move, you can't achieve anything, you can't grow. And so I keep pushing, keep developing, keep evolving. I keep showing what an ordinary person can do when they put their heart, mind and soul into it. I am proving that anybody can achieve the extraordinary, if only they have enough guts and determination and sheer bloody-mindedness to see it through."
Roz Savage is a status quo crusher extraordinaire who I know will inspire you to reveal a better version of who you are at your core.
Roz Savage: Why I'm rowing across the Pacific TEDx talk
Roz Savage – Eco-Adventurer
Set aside some quality time with yourself and write two obituaries. The first obituary is the legacy you dream of leaving behind. The second obituary is the legacy you will leave if you continue your current life path. Compare, and ask yourself, "am I living a life that will leave the world a better place than I found it?"
For a more detailed description about this exercise, check out this link on Roz' website.
• Roz Savage website.
• "Stop Drifting, Start Rowing", Roz' amazing book on Amazon!
• Find Roz on Twitter.
• Find Roz on Facebook.
Are you inspired by this podcast? If so, here's how you can fan the flame for the message:
1. Support the show!
Support the paradigm-altering Unplug movement on Patreon. Every little bit makes a difference!
2. Subscribe & Review the Show on iTunes:
Here's a simple 5-step process to quickly rate, review and subscribe to the show.
You can also now subscribe to the show on Stitcher where the show will now be available all over the world on Stitcher mobile, tablet and web apps and, also in over 4 million in-car dashboards.
3. TELL A FRIEND ABOUT THE SHOW and spread the word FAR AND WIDE!
As always, thank you for listening and thank you for helping to co-create a better world!
Loooove this one! 😀 Roz is amazing! Not just her rowing feats but her passion for change and learning more about how to reach effectively people.
I was really interested in your discussions about introverts. It's so inspiring to hear that you are both introverts and a lot of your status quo crushing guests are introverts too. As a shy introvert myself I have often thought I have the worst personality to change the world. But recently I took the Myers Briggs personality test recently and discovered I share my personality type (INFJ) with some of the world's greatest changemakers – Martin Luther King Jr, Mother Teresa and Gandhi. So that totally blew my theory out of the water and made me realise not only do I have what it takes, I possibly have one of the best personalities out there to be a changemaker. I just need to believe in myself. 🙂
I really loved what you were both saying about effective and compassionate activism too. I think it's so important to look at what is working and what isn't and know how to really reach people. This is one of the reasons I want to study Humane Education so that I know how to be most effective in creating change. I think it's great there are organisations like Faunalytics who are now doing research on this important subject. It's so crucial that we are compassionate changemakers too, that we let go of judgement and we try to understand what has shaped people and made them who they are. I found Marshal Rosenberg and Thich Nhat Hanh's work really helped me to learn non-judgement and compassionate understanding.
Thank you both for a great podcast! I really enjoyed it and I'm feeling all energised and inspired! Looking forward to listening to the one with Roz you just posted this week too.
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Hello, my name is Vincent and i love sas 4.
One of the few Chilean players/Uno de los pocos jugadores chilenos.
No problem for duos;)
( ͡o ͜ʖ ͡o) Happy new year!
Ninja Kiwi and Bloons are trademarks of Ninja Kiwi Limited, registered in the U.S. and other countries
iPhone and iPad are trademarks of Apple Inc., registered in the U.S. and other countries. App Store is a service mark of Apple Inc.

subset: commoncrawl


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Kids are funny. It's one of their qualities that makes all the tantrums and sass and the messes worth it. And while bedtimes can and often are one of the most stressful times of the day (for parents), these kiddos and their strange routines have to make things a little better.
Or, at the very least, more amusing.
#10. That seems inconvenient. Maybe just tell him it's gone?
#9. I mean. At least she's considerate.
#8. It smells better than a lot of other things…
#7. This is just the weirdest thing.
#6. Awww, this is sweet.
#5. So. Flattering.
#4. Some kids have piles of stuffed animals, and some kids have…
#3. I love oddballs.
#2. Leaving without comment.
#1. Maybe it cools her off.
h/t: ScaryMommy


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North Carolina company takes home first place at the Employee Engagement Summit and Awards recently held in Chicago.
At its core, N2 Publishing's mission is about helping people grow professionally and personally. Maintaining that focus – even in times of rapid change – recently netted the company the Employee Engagement Project of the Year Award for its leadership training program.
"For us, employee engagement is simple," said Duane Hixon, CEO of N2 Publishing. "It's as simple as believing our people are smart and responding accordingly. We believe everyone on our team has the ability, personality and drive to be better tomorrow than they are today. Our leadership training program is a result of that."
In 2015, N2 Publishing saw its revenue leap to $100 million and its team expand to more than 200. To grow managers within the ranks, company executives created a pathway where selected participants go through nine months of intensive training.
"Other training programs may focus solely on leadership skills – and of course we focus on that too – but the course is largely designed to teach our leaders how to be leaders specific to N2 standards," Hixon noted. "We heavily cover the topic of culture and how, as leaders, these people will be some of the most identifiable champions of our culture."
The Employee Engagement Summit and Awards program came about from similar thinking, with the aim being to recognize and celebrate the excellence of forward-thinking businesses that put people first and make a real impact in employee engagement.
This year, N2 Publishing shared the stage with a handful of other businesses and organizations, including Home Depot, Ford and March of Dimes.
"The winners have rightly been recognized for excellence in improving employee engagement to drive wellbeing, better work environments and organizational success," said Matt Manners, founder of the Employee Engagement Awards.
Being recognized for how it engages employees is not new for N2 Publishing. Since last year, the company has been placed on more than 10 lists, including Best Workplaces for Recent College Graduates; Best Workplaces for Flexibility; Entrepreneur and Culture IQ's Top Company Culture – Best in Large Enterprise Award; Great Places to Work and Fortune's 100 Best Workplaces for Women; Outside Magazine's Best Places to Work; Best and Brightest's 101 National Best and Brightest Companies to Work For; and Best Employers in North Carolina.
"We believe that N2 is a company founded on its people; we wouldn't be where we are today without our wonderful team," Hixon said.
Ready to be your own boss, determine your own income, and create your own schedule? Apply for our franchise opportunity; it sets passionate, driven people up for success through proven methods and extensive training. Learn directly from our experienced leaders, all of whom started out in the Area Director role themselves.


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Posts Tagged 'Islam'
An Azerbaijani Reflection on the Night of Qadir, and Our Connections with Divinity
The end of Ramazan (also known as Ramadan) draws nigh and just this past week was the celebration of Lailatul Qadr', or the 'Night of Power' (one possible translation). Muslims believe that the revelation of the Quran to the Prophet Muhammad happened within the last 10 nights of the month of Ramazan, on an odd-numbered night. Around here, that means there are 10 nights during this time when the devout will stay up all night at the mosque praying. Muslims throughout the world have been fasting already for the first three weeks of Ramazan. As the end of Ramazan approaches, known as the Eid or Eid al-Fitr, on the 30th and 31st of August this year, I thought I'd share a thoughtful reflection by a blogger, Sabina, on her first experience going to a mosque last week during the Qadir:
I was really excited about the idea of going to the mosque and spending the night there awake. In Azeri, Mosques are called 'Allahın Evi" (the house of God). I truly believed that I was going to be much closer to God. When I was in Georgia, my friends and I went to the cathedral and lit a candle. I was feeling embarrassed that as a Muslim I had gone to the cathedral first. So this was a good chance for me to feel God in another house of His.
However my excitement faded away when I stepped in the mosque. No. I didn't see the mosque, but the yard of the mosque. When I began to follow the crowd, which mainly consisted of males, my sister grabbed my arm and forwarded me to the tent. It turned out that males were going to spend the night inside the mosque with Akhoond, and females were to spend the night in the tent in the yard on the ground covered with old carpets. There was a speaker in the tent to hear the voice of Akhoond.
To be honest, I was really surprised, because I have read a bit of Quran, and God's words say to treat woman kindly. Besides, in our culture, in the buses or other places, males always give their seats to females, or they always seem to be protective. Sometimes extremely protective to females. But no, in the house of God, males agree to stay inside and let females (their mothers, sisters, wives) sit in the tent on the ground in the cold weather. (That night it was drizzling). Another surprising thing was that the women didn't care about it. It was just me asking around why males are inside. My aunt thought I should keep silence. Well I did. But I didn't keep silence in my mind; I really thought a lot but didn't find any answers. Although my sister answered this question, it just seemed a pretext to me.
There are so many ideas going on here. Sabina embarks on a deep reflection on the role of Islam in gender, the complexity of our earthly connections to divinity, against a background of not just Muslim culture but also Azerbaijani culture. The whole post is worth reading to get a full perspective from one Azerbaijani woman on Ramazan, Islam, Azerbaijani culture, divinity, and the questions we should all be asking ourselves.
Ramadan, Coming to You on August 1st
This is my second year in a Muslim country during Ramadan (Ramazan, in Azeri). And it's another time that reminds me that Azerbaijan is not necessarily the most devout of Muslim countries. (Let's chalk that up to 70+ years of Soviet repression, shall we?) When I head to the bank on Tuesday, it's likely that 40% or so of my bank colleagues will be fasting in accordance to the Sawm. This is what I had to say about Ramazan last year, which I'm sure is still applicable (note, however, that we're regularly hitting 100+F in temperatures this year):
One of the big concerns we've had is that this month has been extremely hot. We're talking about mid- to high-90′s each day, no rain, all sun, all the time. That's concerning for folks who are not even drinking water. There have got to be some alternatives that people are pursuing to keep this up. At the bank, I know there have been a few more people complaining of headaches and feeling ill recently, which I'm going to directly attribute to the fasting. Yet, I admire the earnestness with which these people approach the time of Ramadan. It's an impressive undertaking, no matter how hot it is outside.
This is also another time to discuss the religiosity of Azerbaijanis, their relationship to Islam. We've seen other examples of ignoring Islamic principles, such as excessive drinking by Azeri men. Ramadan is no exception. While there are certainly a lot of people fasting during Ramadan, I think it's fewer than I thought. An informal survey of the bank office showed that about a third of the office was fasting, about 16 out of the 50 or so people that work there. Talking with Miri, it's about the same at the TV station. Miri's also a bit more cynical about the whole enterprise. He suggested the other day that while some people fast for religious purposes, there is another subgroup of people who are fasting for more vain purposes, trying to lose weight, or for health. I'm not into criticizing people for fasting for those purposes. But I do find it a little surprising.
This year the month of Ramazan starts officially on August 1, 10 days earlier than last year, according to the Caucasus Muslims Board:
Qadi Council of the Caucasian Muslims Board issued a fatwa on the start of the Month of Ramadan.
An event was held on this occasion at the Caucasian Muslims Board. According to the fatwa, the first day of the Month of Ramadan falls on August 1 of the Christian calendar. July 31 is the night of intention. The Eid ul-Fitr falls on the 29th or 30th of the Month of Ramadan by the hijri calendar – August 30 or 31 by Christian calendar.
One feature that I find particularly interesting about Ramazan is that the myriad important dates during the (lunar) month are fairly vague. Notice above: we're not sure which day the Eid falls on. Other dates, the days on which the Qur'an was revealed to the Prophet or the days on which Shi'ites commemorate the martyrdom of Imam Ali, are similarly uncertain. It all depends on the sightings of the moon.
Maccabi Tel Aviv v. Xəzər Lənkəran: Israeli Football Players on Iran's Doorstep
Well, I doubt that the players from Maccabi Tel Aviv FC are heading down to the border town of Astara, but Lənkəran isn't very far away. We sit about a 30 minute drive north of the border, so when Maccabi Tel Aviv players came to Lənkəran, I'm sure they were closer to Iran than they ever thought they might be. I hadn't even thought of the security implications of tonight's match until I was sent this news article:
Some 15,000 fans, 400 policemen and 300 soldiers will meet Maccabi Tel Aviv for its return leg tonight against Khazar Lankaran in Azerbaijan, just 40 kilometers from the Iranian border. In a move to prevent Iranian citizens from entering the stadium, every fan will have to present a passport. The 30 Maccabi fans who made the journey in three flights will be given heavy security.
A few things: First, those 30 Maccabi fans aren't very travel-savvy. They should be able to get to Azerbaijan with only one layover. If they were really savvy, they would realize they could have flown to Moscow or St. Petersburg and been on a flight directly from there to Lənkəran. Second, the article describes later how the Maccabi team complained about the conditions of getting to Lənkəran. Same goes for them: if they were any good at international travel, they should have been able to get a flight into Lənkəran (it's a football team: shouldn't they have their own chartered flight?) and skipped the "rickety bus" they talked about. And even if they had taken a bus from the Baku bus station, it would have been air-conditioned. What buses are they talking about? Third, those security measures are interesting. At the last game I went to, there was a very small crowd of fans for the other team that was surrounded by security for the entire game. And it seems that no matter who the opponent is, security at these games is always plentiful, with local military regiments lining up around the pitch and into many of the seating sections.
Last, people around Lənkəran have been talking about this game all week. I've been asked tens of times in the last few days if I've bought a ticket yet (I haven't) and I'm sure that the stadium will be packed. For the fans' sakes, I hope that the game is better than the last one I went to, against a team from Moldova. For this upcoming game, we know that Xəzər Lənkəran, this year's Azerbaijan League champion, took the loss in the last meeting of these two teams in Israel a few weeks ago. Hopefully Xəzər can take some lessons learned and advantage of the hometown crowd to turn that 3:1 score from the loss into a 3:1 win here in Lənkəran.


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I will now begin granting limited access to users that have requested it, however all edits will be reviewed by either Vernon CHARTIER or myself for the time being until we're sure the user knows how the new system works (and he and I are still learning it too!).
NOTE: The maps feature does not seem to work well on GOOGLE Chrome, so use the internet browser bundled with Windows.
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Nicholas & Angelique SHORKEY
Nicholas and Angelique [Dagneau] SHORKEY. Copy from original tin-type. Taken c.1865.
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Classic "Footprints in the Sand" theme. Great as inspiration art. There are three fields of text: Line one has 13 lines maximum (e.g. inspirational poetry or quote), Line 2 has 3 lines maximum (e.g. Coach's or player's name), and field 3 has 3 lines maximum (e.g. Date, or Name, or Title).
Posted by Kelly on 7th Jul 2015
I NEVER do reviews but I felt that this one deserved it! I am overjoyed at the final results! I did the frame with brownish matte. The lines and spacing were exactly as I had laid out on the screen. I used completely different wording from the example as a gift for a friend and it turned out amazing! As long as you adhere to the character restrictions per section, you can write anything and really make it personal! It was a bit pricey but worth it for all that personalization.
Posted by Unknown on 22nd Aug 2014
Very happy with the finished product. I liked the opportunity to proof your order prior to delivery.


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By Emma Naille
Recently, I listened to a podcast called "White, Evangelical, and Worried About Trump." And I can't stop thinking about it.
Since starting college, I started listening to "The Daily," a podcast by the New York Times, on the way to class each morning in an attempt to stay connected to what is going on in our country and in the world.
When this podcast was released, and I saw the title of the podcast and paused. I almost just hit play on my current favorite playlist, not wanting to start my day with this podcast.
But I didn't. I hit play on the podcast. I listened. And I am oh so glad.
Despite its name, this podcast is mostly not about Trump. It is about Tess Clarke and her story. Tess Clarke is a Christian from Texas who voted Democrat for the very first time in this past midterm election.
She spoke about how growing up in a Christian home and going to a Christian school, where she was taught that Christians are Republican. And that was the end of it. So for the majority of her life, she voted Republican. She said it "felt righteous."
But after teaching immigrant children and witnessing families separated at the border, Clarke said Jesus began to "change her heart." She decided to vote Democrat because she felt the Republican party platform no longer represented her values. She said, "I care as much about babies at the border as I do about babies in the womb," to explain how she remains pro-choice but switched parties because she believes Jesus values all lives.
It is not that Clarke, and many women like her, are not pro-life anymore, they are simply "pro-all life" as Clarke says. She poignantly explained the reality that we don't live "single-issue lives," and said, "the more I understand who Jesus is, my faith informs my politics."
Clarke then explains how she wrote part of an article for The New York Times and her dad, who remains strongly Republican, has not read the article. My heart broke for her at that moment that she felt disconnected from, maybe even unloved by, her dad in that way.
The podcast ends with a phone conversation between Clarke and her dad about politics. I personally found the conversation very encouraging, because although I disagree with almost everything her dad said and was disheartened by the way he portrayed Jesus, I found Clarke's ability to graciously, truthfully, and lovingly talk to her dad about her views very encouraging. It showed me that two people can love each other and disagree. In the end, she thanked her dad for being willing to sit down for the conversation, which I found to be representative of how compassionate a Christian should be.
I can't stop thinking about this podcast because of how Clarke told her story and portrayed Jesus. She was genuine and authentic and spoke of the Jesus I know and love, which I haven't ever seen "Christians" doing in the media. Clarke sounded so much like many Christian women I know. I could hear her heartbreak and her love for Jesus in her voice, and I felt it in my heart.
I related so much to her story, with the realization Christian does not equal Republican. She voiced many thoughts that I had been too afraid to share with my Republican, Christian friends.
After listening to her story, I felt as though it needed to be shared. I contemplated posting the episode on my Instagram story. I went back and forth about it because I never share my political thoughts on my social media. But, I decided that it was too important and too truthful not to share.
My post was met with a response of support by several of my friends, thanking me for posting it and sharing their love for the podcast. I'm sure many people saw the title and decided not to listen. I'm sure some people listened to the podcast and disagreed. But I'm glad my moment of courage allowed people to hear the truth.
This podcast is a reminder that Christian does not equal Republican. A reminder that Christians, Republicans, Democrats, immigrants, and every other group of people is just that. A group of people, with real-live souls.
If you're Christian, Republican, Democrat, or none of them, I recommend listening to this episode of "The Daily." I think it will do our country, not to mention the world, some good if we all take steps to understand each other's viewpoints and try to love each other even when we disagree.


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By Todd Johnson
Meet 5 North Carolina girls who're approximately to alter how you take into consideration friendship. For Rhonda, a gritty, fun-loving hairdresser in tight denims, the attractions and scents of Ridgecrest Nursing middle are miserable. yet prior to she will be able to swap her brain approximately operating there, citizens glue themselves to her: Margaret, droll and whip-smart, with a will of iron that by no means fails her even if her physique does, and Bernice, an avid state song fan who's hardly ever lucid. including Lorraine, their church-going, God-questioning nurse, and her daughter, April, vibrant and bold, they lock fingers in braveness and humor for a trip that speaks to us all—of how we are living and die, of ways we like and forgive.
Download E-books InStyle [UK] (May 2012) PDF
She's continually some of the most wanted entrance web page matters, and Jennifer Aniston lent her promoting energy to the canopy of the could 2012 factor of InStyle UK.
The 43-year-old actress introduced her enthralling seems to the magazine's unfold whereas starting up approximately themes akin to her present lifestyles state of affairs, what makes her think previous and her pink carpet secrets and techniques.
Download E-books Maxim (April 2015) PDF
Maxim, April 2015
Download E-books Dreaming in Cuban PDF
"Remarkable...An problematic weaving of dramatic occasions with the supernatural and the cosmic...Evocative and lush...A wealthy and haunting narrative, an exceptional new voice in modern fiction."
Now on hand in a Spanish language variation from Ballantine Books.
Here is the dreamy and bittersweet tale of a relatives divided by means of politics and geography by means of the Cuban revolution. it's the family members tale of Celia del Pino, and her husband, daughter and grandchildren, from the mid-1930s to 1980. Celia's tale mirrors the mystical realism of Cuba itself, a rustic of good looks and poverty, idealism and corruption. DREAMING IN CUBAN provides a different imaginative and prescient and a haunting lamentation for a previous that will were.
Download E-books Women Don't Ask: Negotiation and the Gender Divide PDF
By Linda Babcock, Sara Laschever
When Linda Babcock requested why such a lot of male graduate scholars have been educating their very own classes and so much woman scholars have been assigned as assistants, her dean acknowledged: "More males ask. the ladies simply do not ask." It seems that whether or not they wish larger salaries or extra aid at domestic, girls usually locate it not easy to invite. occasionally they do not know that vary is possible--they have no idea that they could ask. occasionally they worry that asking may well harm a courting. and occasionally they do not ask simply because they have discovered that society can react badly to girls announcing their very own wishes and needs.
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With women's growth towards complete monetary and social equality stalled, women's lives changing into more and more advanced, and the constructions of companies altering, the facility to barter is not any longer a luxurious yet a need. Drawing on learn in psychology, sociology, economics, and organizational habit in addition to dozens of interviews with women and men from all walks of existence, Women do not Ask is the 1st booklet to spot the dramatic distinction among women and men of their propensity to barter for what they need. It tells ladies the way to ask, and why they should.
Download E-books When Wallflowers Dance: Becoming a Woman of Righteous Confidence PDF
By Angela Thomas
Note:This ISBN isn't a examine advisor
When we have been , we have been now not babies-we have been turning into little women. And once we have been 13, we have been leaving early life at the back of, turning into younger women. yet someplace alongside the way in which, we stopped turning into. We grew to become "un-women." Wallflowers who're simply respiring and smiling and mixing in to stick out of the way.
That isn't really what God had in brain while He created us. He desires us to maintain turning into. He desires us to develop into robust, decisive, clever, artistic, passionate, courageous-all the issues we have now dreamed of changing into. while Wallflowers Dance is a clean problem to girls who've lived hesitant, wary lives yet lengthy to wreck loose and dance!
Using either Scripture and tale, Angela Thomas addresses the attributes of "becoming" and the liberty we've got in Christ to maintain constructing the features that replicate our God-given longings.
Download E-books The Action Heroine's Handbook PDF
By Jennifer Worick, Joe Borgenicht
Get a few Action!
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Download E-books Mary Wollstonecraft: A Literary Life PDF
By Caroline Franklin
Mary Wollstonecraft used to be a unprecedented person, but her literary existence exemplifies what number girls of her time used print tradition to lead to swap. This research argues that Protestant society had regularly sanctioned women's position in spreading literacy, yet this grew to become politicized within the 1790s. Wollstonecraft's literary vocation was once formed via the excessive expectancies in either the unconventional circles of Unitarian writer Joseph Johnson, and the Girondins in progressive Paris, of the facility of print to teach and reform participants and society.
Download E-books Contours of Citizenship: Women, Diversity and Practices of Citizenship (Gender in a Global/Local World) PDF
By Margaret Abraham
In an more and more globalized international of collapsing fiscal borders and increasing formal political and felony equality rights, energetic citizenship has the capability to extend in addition to deepen. even as, with the increase of neo-liberalism, welfare country retrenchment, decline of kingdom employment, re-privatization and the emerging hole among wealthy and bad, the commercial, social and political citizenship rights of yes different types of individuals are more and more curtailed. This booklet examines the complexity of citizenship in old and modern contexts. It attracts on empirical learn from a number of nations, contexts and techniques in addressing girls and citizenship in a global/local global and covers a range of numerous concerns, either current and earlier, to incorporate immigration, ethnicity, classification, nationality, political and monetary participation, associations and the non-public and public spheres. This wealthy assortment informs our realizing of the pitfalls and chances for ladies within the endurance and alterations in the contours of citizenship.
Download E-books A House in the Sky: A Memoir PDF
By Amanda Lindhout, Sara Corbett
BREAKING information: Amanda Lindhout's lead kidnapper, Ali Omar Ader, has been caught.
Amanda Lindhout wrote approximately her fifteen month abduction in Somalia in A condominium within the Sky. it's the New York Times bestselling memoir of a girl whose interest led her to the world's such a lot distant places after which into captivity: "Exquisitely told…A younger woman's harrowing coming-of-age tale and a unprecedented narrative of forgiveness and non secular triumph" (The big apple occasions e-book Review).
As a toddler, Amanda Lindhout escaped a violent loved ones via paging via problems with National Geographic and imagining herself vacationing its unique locales. on the age of 19, operating as a cocktail waitress, she begun saving her advice so she may possibly shuttle the globe. desiring to comprehend the realm and reside an important existence, she backpacked via Latin the USA, Laos, Bangladesh, and India, and emboldened by means of every one experience, went directly to Sudan, Syria, and Pakistan. In war-ridden Afghanistan and Iraq she carved out a fledgling occupation as a tv reporter. after which, in August 2008, she traveled to Somalia—"the most deadly position on earth." On her fourth day, she used to be kidnapped by way of a bunch of masked males alongside a dusty road.
Held hostage for 460 days, Amanda survives on memory—every lush element of the realm she skilled in her lifestyles sooner than captivity—and on technique, fortitude, and desire. whilst she is so much determined, she visits a home within the sky, excessive above the girl stored in chains, within the dark.
Vivid and suspenseful, as artfully written because the best novel, A residence within the Sky is "a searingly unsentimental account. eventually it truly is compassion—for her naïve more youthful self, for her kidnappers—that turns into the main to Lindhout's survival" (O, The Oprah Magazine).


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In a remarkable experiment, biologists have documented gorillas in the wild are not only good at using simple tools, like a stick to poke in a swampy pool of water to check its depth, but in more sophisticated ways when given more sophisticated tools.Recently, in the Republic of Congo, scientists saw gorillas using objects in the wild as tools. So, scientists secretly placed more complex objects in plain view of the great apes and the results were shocking."This is a truly an astounding discovery," said Professor Morris Sleevebaker. "The great apes knew what to do with thermometers, can openers, flashlights and when they didn't know exactly what to do with them, they improvised." Digital visual documentation soon will be released, showing an alpha-male great ape taking the temperature of his mate using a rectal thermometer, which is just one of the fascinating acts. In another scene, a young gorilla builds a replica of the Taj Mahal using an erector set. Scientists' observations were made in a marshy clearing called Mbeli Baia, located in Nouabale-Ndoki National Park. It began, they said, with a great ape picking up a revolver and some bullets and not knowing the relationship between the objects. A month later, the same gorilla had not only figured out that the bullets were meant to go into the gun barrel, he had also shot three observing scientists at forty paces. The scientists lived to be astounded."I never knew what hit me," said Roberto Pileplant, one of the victims. "Good thing we didn't give the ape a shotgun.
Thursday, November 23, 2006
Gorillas May Make Teachers Obsolete
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Ibiza restaurants: Jig-caught squid at Alabastro Lounge
If the Mediterranean Sea could be captured in a dish it would be this – the locally and sustainably caught squid cooked to perfection in two ways fro Alabastro Lounge at Aguas de Ibiza Lifestyle & Spa. Tender rings are stuffed with a creamy salsa and the tentacles come with the perfect crunch. Young shoots add a gentle hint of garlic; dabs of deconstructed kimchi give just a hint of spice and gossamer lemon foam the exact lightweight acidity.
Delivered on plate reminiscent of a wind and wave worn stone and matched with a glass of crisp white wine, this is the perfect summer in culinary form. Take a seat in the verdant terrace and allow your senses to be taken on the ultimate voyage.


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February 19th, 2019, Shenzhen - OPPO and Ericsson today announced the signing of a multi-year global patent license agreement between the two companies. The agreement covers patent licensing, and collaboration on a number of business projects.
Adler Feng, Head of OPPO Intellectual Property Department, said that the agreement will lay a solid foundation for further cooperation between the two companies in the 5G era. "OPPO has always placed intellectual property rights as our top priority. We look forward to working with Ericsson to drive cutting-edge innovation in products and services."
Ericsson is one of the leading providers of Information and Communication Technology (ICT) in the world.
Gustav Brismark, Chief Intellectual Property Officer at Ericsson, says: "This important deal confirms the value of our patent portfolio and further validates the Ericsson FRAND licensing program. Ericsson has signed more than 100 patent license agreements to date, and we are delighted to sign a mutually beneficial agreement with OPPO."
Following a patent-first strategy, OPPO always attaches great importance to the patent and reserve accumulation. As of January 2019, the company has filed more than 33,000 patent applications worldwide and owns more than 8,000 granted patents. The deal with Ericsson is the latest in a series of patent license agreements by OPPO with key telecommunication industry partners including Qualcomm, Dolby and Nokia. OPPO will continue to work closely with leading industry partners to bring the best products and experiences to consumers globally.
About OPPO
OPPO is a leading global smartphone brand, dedicated to providing products infused with art and innovative technology. Based on the brand elements of young, trend-setting and beauty, OPPO brings consumers a delightful experience of digital life.
For the last 10 years, OPPO has been focusing on manufacturing camera phones, while innovating mobile photography technology breakthroughs. OPPO started the era of Selfie beautification, and was the first brand to launch smartphones with 5MP and 16MP front cameras. OPPO was also the first brand to introduce the motorised rotating camera, the Ultra HD feature and the 5x Dual Camera Zoom technology. OPPO's Selfie Expert F series launched in 2016, drove a Selfie trend in the smartphone industry.
In 2017, OPPO was ranked as the number 4 smartphone brand globally, according to IDC. And today, OPPO's business has covered more than 35 countries and regions, and has 6 research centers worldwide, providing excellent smartphone photography experience to more and more young minded people around the world.


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Read More Reviews on TripAdvisor
15 Village Drive, Westerose, Alberta, T0C 2V0 17805860006
Nestled in the heart of The Village At Pigeon Lake Resort & Town Centre, their hotel accommodations have all the warmth and charm of country living. Picture yourself in the midst of tranquility with all the modern conveniences at your fingertips. Their 35 room hotel offers the perfect location for business retreats & personal getaways.


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Kwetsani Camp
price per person sharing
Kwetsani Camp is situated on an elongated island covered with palm, mangosteen and fig trees in the centre of the Jao Concession, within Moremi Game Reserve. The surrounding floodplains are home to a number of "Delta specials" – species that are found in few other places on Earth. Some of these may even be seen from the privacy of one of our five "tree-house" chalets, beautifully furnished en-suite units each comprising a bedroom and lounge, and made of canvas, wood and glass. Five beautifully furnished "tree-house" tents, each with en-suite bathroom and outdoor shower, are elevated so as to take in the view. The main area at Kwetsani Camp includes a dining room and lounge area situated under a cool thatched roof, and leads onto an expansive wooden deck that looks out over an enormous floodplain often dotted with plains game.
Kwetsani's main area is covered by a cooling thatched roof with the comfy sitting area, dining area, gift shop and bar area leading directly onto an extensive wooden viewing deck, which incorporates some of the surrounding trees. Early morning, late afternoon and early evening game drives are offered, as are guided nature walks and canoe and motorboat safaris. If you want a truly relaxing day, spend the day fishing (catch and release) or just watch animals passing by camp as you cool off in the swimming pool.
Whether you're looking for luxury sojourn or a laid-back holiday with affordable accommodation, we can make it happen!
Once we have all your information and understand the vision for your holiday, we'll start planning your trip.
With all your plans in place, all you need to do is pack your bags, hop on a plane and travel over land and sea to your destination of choice!


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The head of the Apprentice Boys of Derry has urged unionists to "come together", after more loyalist bands vowed to boycott the association.
It comes after a row broke out at a parade in Londonderry on Saturday when a visiting flute band wore shirts with a Parachute Regiment emblem and the letter 'F' – in support of a former soldier facing murder charges over the deaths of two men on Bloody Sunday.
Police flanked Larne-based Clyde Valley Flute Band and a large contingent of PSNI Land Rovers later stopped the band's bus on its way home, with officers recording the names of some members.
In a statement on Tuesday, Governor Graeme Stenhouse said the Apprentice Boys recognise the potential upset caused to nationalists by the emblem worn by the band.
He added that the association had no prior knowledge of the uniform worn by Clyde Valley.
Representatives of the ABOD are due to meet with members of Clyde Valley on Thursday night to discuss the matter.
As reported by the News Letter on Wednesday, Mr Stenhouse's remarks resulted in several loyalist bands threatening to cut ties with the ABOD in a show of solidarity with Clyde Valley.
Cloughfern Young Conquerors, Rathcoole Protestant Boys, both from Newtownabbey, and Dundonald-based Pride of Ballybeen Flute Band all said they would boycott future ABOD demonstrations.
Cairncastle Flute Band has now also weighed in and said it is withdrawing support for the association, stating: "It is our view that in demonstrating a visual symbol in support of the injustice faced by soldier F and indeed many of the servicemen tasked to serve Queen and country in the Northern Ireland conflict, the Clyde Valley Flute Band have broken no laws, and have not incited violence or sectarianism."
Speaking to the News Letter, Mr Stenhouse urged unionists not to "fight among themselves".
He added: "I would call on all participating bands and unionists in general to come together. I want to reiterate that we did not blame the band, and we did not say they did anything wrong."
Clyde Valley FB plans to hold a rally and parade in Larne on October 5 in response the actions of police, and has invited members of the Apprentice Boys to take part.
Meanwhile, DUP leader Arlene Foster said her party believes last week was "not a good week for policing" in NI, and compared the PSNI's handling of the parade in Londonderry to a republican parade in Strabane the previous weekend.
During the Strabane National Hunger Strike Commemoration, Sinn Fein MEP Martina Anderson announced during a speech that "Britain's days in Ireland are numbered" and shouted the IRA slogan 'Tiocfaidh ar la'.
This was followed by the decision of the PSNI to pull out of Belfast's New Lodge area during disorder linked to an anti-internment bonfire.


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Women's Football News
Bedfordshire & Hertfordshire League
Leighton Utd Vixens need to win two of their remaining five games in order to clinch the title. They moved closer to their target on Sunday when beating Sherrardswood 8-2, Shanice Sanderson netting four along with Shona Lee (2), Karis Richardson and Sammy Beharry. Garston's challenge is all but over after losing 2-1 to Flitwick Ladies who scored through Nicola Henman and Zoe Molloy. Sharnbrook are off the bottom after doubles from Emma Butler and Sally Dayus gave them a 4-2 victory over Harvesters.
In Division Two, Elle Georgiou netted twice with Natasha Coppin, Ivy Betts and Brooke White adding the others as Bishop's Stortford Town defeated Woburn Lionesses 5-2. Hitchin Town won 2-0 against Crawley Green 2-0 thanks to Emma Chaffey and Chanel Sherriff-Geary.
AFC Kempston Girls & Ladies are just five points off the pace in Division Three after a Chloe Williams hat-trick, Grace Fuller double, Rebecca Smith and Shelbee Clarke gave them a 7-0 victory over Evergreen Ladies. Bedmond Ladies follow on after winning 5-1 at Welwyn Garden City, Molly Peters netting a hat-trick and Sarah Gunn the other two, while Kings Langley leapt off the bottom on the back of a 6-2 success against Panshanger. Kimberley Nield led the scoring with a four-goal haul and there was one apiece from Rachael Lee and Phoebe Henderson-Barnes.
Birmingham League
Stockingford AA Pavilion have matters in their hands right now in the title race after they beat rivals Sandwell Ladies 5-1. Stockingford are in third place, level on points with Sandwell, and one point behind leaders Atherstone Rangers with games in hand. Rugby Town follow on after defeating Continental Star 2-1. Tipton Town added to Solihull Moors' woes, the 5-0 win putting a gap of nine points between the two teams.
Stourbridge narrowed the gap at the top to two points in Division One by winning 6-2 away to Walsall Development Swifts and they are set to meet leaders Coundon Court in an important clash this Sunday. Hillcrest meanwhile banished any lingering fears of the bottom two with a 5-0 victory over Walsall Wood.
It's as you were at the top of Division Two; Wednesfield defeated Leamington Hibernian 10-1 to stay three points ahead of Coleshill Town, 6-1 winners over Rubery Ladies Res. Starlands St Annes won 11-1 away to Kingsbury & Coleshill and this takes them into fourth, ahead of Tame Bridge who were beaten 5-2 by Alvechurch.
S-Tech Cambridgeshire League
Riverside Rovers stretched their lead at the top to four points when Annie Posnett and Hannah Stubbs gave them a 2-1 victory over Fulbourn Bluebirds. Cambridge University meanwhile defeated Isleham Utd 7-1, the prolific Amanda Wainwright netting five times along with Lynn-Jones Taylor and an own goal.
In the Championship North, Bourne Ladies moved to within one point of the leadership after winning 1-0 at Wisbech St Marys, Claire Lawrenson scoring the only goal. Rebecca Corby, Kerri-Ann Holden-Jones, Kirsty Mee, Hannah Worthington and an own goal ensured that third placed Stamford beat Downham Town 5-0.
One match was played in the Championship South, Paige Archer and Hannah Hutchinson scoring the goals as Little Paxton drew 2-2 with March Town Utd, who replied through Anna Hatcher and Emma Searle.
Cheshire League
Wallasey Wanderers are through to the semi finals of the Challenge Cup, where they will meet AFC Stockport, after they narrowly won 4-3 against Altrincham.
In the league, bottom placed Runcorn Linnets enjoyed only their second victory of the season, winning 3-1 against Chester City.
Cornwall League
Penzance swept into the semi finals of the League Cup after running out 9-0 winners over RNAS Culdrose. Naomi Broome, Lucy Brown and Lamoma Fellows all netted two goals apiece with Danielle Barnes, Katy Brewer and Georgina Triggs joining them on the scoresheet. The other team definitely through are Mullion, who beat St Teath 3-1.
Derbyshire League
Dronfield Town will play Hasland in the Division One League Cup Final after winning their respective semi finals on Sunday. Annabel Davies, Rebecca Hill and Ruby Burns scored the goals as Dronfield won 3-1 against Mackworth St Francis and Hasland defeated Castle Donnington 4-2, courtesy of a Leann Cole hat-trick and Samantha Pearce.
Leaders LFC Buxton are out of the Division Two League Cup, beaten on penalties by Belper Town after the sides had battled out a 1-1 draw. Belper, who scored through Emma Brentnall, will face Woodlands Ladies in the Final after Emily Foss, Katie Mayfield and Briony Moir all found the net to earn them a 3-2 win away to Pride Park Ladies.
Ashbourne Ladies are up into fourth place in the congested Division One table after a Sam Glanville goal gave them a 1-0 victory over Wirksworth Colts.
Hilton Harriers emphatically moved off the bottom of Division One by scoring fourteen times against St George's. Emma Shaw and Beth West both bagged hat-tricks with braces from Emma Fletcher and Emma Walsh, and there was one each from Mia Branston and Amy Buxton.
Westward Developments Devon League
Exeter & Tedburn Rangers clinched the Premier Division title as they beat near neighbours Budleigh Salterton and their rivals, Activate lost away to University of Exeter. Goals from Abi Breban, Nicola Brown, Emma Mingo and Becky Folds gave Rangers a 4-1 win over Budleigh, who replied through Sarah Burke. Imogen Wade-Palmer and Waseelah Al-Khafaji scored the two goals that dented Activate's title challenge, as Uni won 2-1.
There were plenty of goals in Division One! University of Plymouth went on the rampage at home to Okehampton Argyle, rattling in fourteen goals without reply. Becky Richards helped herself to a double hat-trick, Alice Nutkins scored three times and there were single strikes for Hazel Barnett, Angela Heard, Harriet Ives-Owen, Hannah Fletcher and Emma Partridge. Brixham Villa could only muster nine players for their trip to play Newton St Cyres, who showed little mercy winning by eight goals. The half time score was 6-0, so they eased off in the second half! Ana Holmes bagged a hat-trick, Lou Page and Loren Eginton scored twice and Amy Salter added the other one.
Durham League
Durham Women ran out 4-1 winners over Gateshead Rutherford Ravens to preserve their seven point lead over Consett Ladies, who won 4-2 away to Bishop Auckland Girls. Seaton Carew crushed Coxhoe Utd 13-1 to keep hold of third place, just ahead of Willington who were 4-0 victors at Consett Belles.
There was a significant result in the Development Division where leaders St Cuthbert's Ladies were beaten 2-1 by South Shields, who are now one point behind them and with a game in hand. Bishop Auckland Ladies kept themselves in the mix as they slammed Washington 18-1. Seaton Carew Development defeated St Cuthbert's Amazons 3-0 and Darlington Spraire Ladies edged out Boldon Development by the odd goal in nine, but the happiest team in the league would have been Swalwell Ladies who registered their first point from a 1-1 draw with Farringdon Detached Ladies.
Essex League
It was another rain affected week in the league which meant widespread postponements due to waterlogged pitches, with only three matches managing to survive.
In the Premier Division, Collier Row Tigers travelled to Beacon Hill Rovers, looking for a win to move into third place but both sides had to make do with sharing the points after they drew 1-1.
Hullbridge Sports' Division One title challenge took a massive dent as they went down 3-2 to Little Thurrock Dynamos Res, who leapfrogged over their opponents into fourth place. Wickford Town meanwhile made the short journey along the A127 to Southend and enjoyed their trip to the seaside with a 4-1 win at Ekco Whitecaps.
Gloucestershire League
Almondsbury UWE's run of victories has taken them to the top of the table and they got there in style, running out 3-0 winners over previous leaders Cirencester Town. Hannah Thompson scored twice and Jamie Worlock the other to see their side open up a two point lead over their opponents. Forest of Dean are the team which has matters in their own hands though and they remain on course after beating Dursley Town 2-1, thanks to Tara Rutter and Sarah Smith. Wootton Bassett Town and Longlevens battled out a 1-1 draw, Sam Wood scoring for Bassett. Oldland Abbotonians meanwhile kept their hopes alive with a 3-1 win against local rivals Bristol & West. After Imogen Kuseri had put B&W ahead, Oldland hit back to take the points through a Jess Cole double and Lydiya Myckalechko. Cheltenham Town Development are starting to find their best form and are out of the bottom four following a 6-1 victory over AEK Boco. Layla Hiorns hit a hat-trick, Molly Kilpatrick weighed in with a brace and Sophie Wyatt rounded off the scoring with a long range strike.
AEK Boco Development march on at the top of Division Two, staying ten points clear after beating Lockleaze Community 7-0. Lucy Atkinson led the scoring with a hat-trick, Courtney Smith added two and there was one apiece from Kaylisha Thornwell and Jade Cook. St Nicholas Res keep up the chase in second, they scored eleven without reply away to Cotswold Rangers. Charlotte Davis and Libby Bell each hit hat-tricks, Poppy Coles added two and the tally was completed by Becky Rexworthy, Lauren White and Sarah Price. Bristol Ladies Union Development's 5-0 victory over Mitcheldean has taken them back into third place. Poppy Warren was on target twice along with Alice Bonham-Carter, Sophie Cooper and Ceri Harland. Bishop's Cleeve and Abbeymead Rovers battled out a 1-1 draw and Cirencester Town Development won for the second time this season, 3-2 against Quedgeley Wanderers.
Greater London League
Northwood kept their title hopes alive with a 2-0 win away to Hampstead, Holly Gilder and Leanne Jones netting their goals. Jodie McClelland and Kally Wilson were on target for Luton Town Hatters in their 2-2 draw with Wealdstone, who replied through Rosie Watts and Stevie Wickes. Francesca Cagetti (2), Helen King and Egle Trezzi were on the scoresheet as Hackney defeated Bromley 4-0 whilst Carly Williams netted for Enfield Town Res as they drew 1-1 with Comets.
Wealdstone Res narrowed the gap on leaders Tower Hamlets in Division Two North with a huge victory over Hampstead Res, which included nine-goal hauls from Annie Hewitt and Lauren Hole. Denham Utd Res lost ground as they were beaten 5-2 by Camden Town Res for whom Gemma Olds (2), Alicia Bravo, Carla Carvalho and Rebecca Levy were on the mark. Sherise Binns netted both goals to give Headstone Manor a 2-1 win at Brook House.
The title race is over in Division Two South with Hampton & Richmond Borough being confirmed as Champions following their 1-0 win over second placed Chobham Burymead. Louise Clarke scored the only goal of the game to put her side beyond the reach of her rivals. Godalming Town remain in the running for the runners-up spot after Grace Merry (2) and Louise Skerry gave them a 3-0 success away to London Phoenix.
Division Three North leaders Tower Hamlets Res went down to a 1-0 defeat at the hands of Hackney Res, for whom Kimberly Horne netted the only goal. Old Actonians Res won 4-1 against East London with strikes from Resham Chaudry, Melanie Johnson, Emma Mulhern and Freya Hepworth-Lloyd.
Victoire Ladies moved further ahead at the top of Division Three South after winning 8-1 away to Orpington. Katie Jackson and Sherelle Walters each hit hat-tricks with Siham Dammany and Danielle De Souza adding the others. Second placed Club Langley were beaten 2-1 by Putney Vale, who scored through a brace from Becky Kil.
Greater Manchester League
FC United of Manchester beat Avros 13-0 to go through to the semi finals of the Challenge Cup. Joining them in the last four are two Division Two sides - Little Lever SC, 2-0 winners at Oldham Athletic, and Uppermill who beat Reddish North End 4-3.
Chorltonians won 2-1 against Beechfield Utd, meaning that the top three in Division One are covered by just three points.
One match was also played in Division Two, Manchester Rovers winning 5-1 away to Moorside Rangers to move themselves into second place.
Hampshire League
Winchester City Flyers continued their quest for the League and Cup 'double' by reaching the Invitation Cup Final with a 3-1 win over Mudeford Phoenix, goals coming from Kayleigh Moss (2) and Georgie Parks. Their opponents in the Final will be - Winchester City Flyers Res! Georgina Axton and Amelia Cutler were on target to give them a 2-1 victory against Warsash Wasps and set up an 'in house' Final.
AFC Bournemouth are in the Junior Cup Final and will be eyeing up a second trophy of the season, after Danielle Ormesher (2) and Jade Tucknott (2) saw them to a 4-0 semi final victory over Horndean.
In Division Two, Kingsclere and Bursledon battled out a 1-1 draw with goals frm Rosie Wybrow and Tash Konczak respectively.
The honours were also even in the solitary Division Three game, Alderbury and Sholing sharing six goals. Kelly Burton netted twice and Hannah Holzer the other for Alderbury, while Sholing replied through a Brooke Veal-Weaver brace and Chloe Brown.
Lancashire League
League leaders Preston North End Res completed the League Cup semi final line up after beating Morecambe A 9-1. Abigail Wignall and Victoria Yee each hit hat-tricks along with Emma Hickson, Alisha Houghton and Heather Crook for Preston who will play Penwortham Girls in the last four.
Penwortham themselves had a good win in Division One, beating Haslingden 5-3 to consolidate second place in the table. Burscough Dynamo meanwhile ran out 7-1 winners away to Pennington.
In Division Two, Blackpool Wren Rovers Res went level on points with third placed Burnley Girls & Ladies Res after beating them 2-1.
Liverpool League
One game was played in the league on Sunday and it failed to produce any goals, South Liverpool sharing a goalless draw with fifth placed Liverpool Marshalls Feds.
Midwest Counties League
Hereford LC require seven points from their last five matches to sew up the title after they won 4-1 against Welland Ladies and Evesham Utd went down to a 4-2 defeat at the hands of Ludlow Ladies. AFC Bridgnorth took the opportunity to move above Evesham into second place via a 4-0 success away to WCT Raiders. Bartestree follow on in fourth after scoring eight without reply past Wyre Forest Phoenix Res, just ahead of Cookley Sports who were 7-0 winners over Droitwich Spa Belles.
Norfolk League
Thorpe Utd cut the gap on league leaders Aylsham Town to three points after goals from Judith Bloomfield, Charlotte Groves, Hayley Kindred and Kirstie Kindred saw them to a 4-1 victory away to Bungay Town.
Tiffany Forshaw hit a hat-trick with other goals from Natasha Rutter, Leanne Sloan, Hazel Shepherd and an own goal as Division Two table toppers Brandon Town defeated Bohemians 7-1. Nikki Wigg went nap with a five-goal haul for third placed Kirkley & Pakefield in their 9-1 win against Freethorpe. Gemma Farman (2), Abbie Knights and Selina Rowland added the other goals to keep their side just in front of North Walsham Angels, who beat Morley Ladies 3-2 thanks to a Luci Middleton hat-trick. Rosie Clark scored the goal for Harleston as they shared a 1-1 draw with Sprowston Res.
Wymondham Town booked their place in the League Cup semi finals by beating Stalham Town 5-0. Laura Hammerton and Louise Rout both netted doubles and Emily Anderson was also on target.
North Riding League
York City Res extended their lead to seven points after a Rachel Harding goal gave them a 1-0 win against Stokesley. Guisborough Ladies are now in second place following their 2-1 victory over Brompton in which Kim Skiba and Ruth Wilson scored. York RI meanwhile were 6-0 winners over Catterick Garrison.
Northamptonshire League
Northampton Town are through to the Final of the League Cup after a Daniella Snowden brace and Aimee Smith gave them a 3-1 semi final victory over Thrapston Town, whose consolation came from Hannah Pendred.
In the league, a Georgia Webb hat-trick and Becky Pinto earned Moulton Ladies A a 4-1 win away to Rothwell Corinthians Res.
Nottinghamshire League
Ollerton Town moved to within two points of leaders Clifton after they won 2-0 away to Bingham Town, goals coming from Charlotte McClaren and Charlotte Appleby.
Sheffield & Hallamshire League
This season's title could be decided on Sunday. Leaders Oughtibridge need just a draw at home to their only challengers Handsworth who must win and then follow up with maximum points from their subsequent four games. Handsworth were boosted by their biggest win of the season, 10-0 against Edlington Royals. KD Roberts, Mae Spencer and Beth Thomas bagged hat-tricks with Emma Rowland the other scorer. Lucy Ridley, with four, Rebecca Hargreaves, Kelsey Murphy-Bigley, Michelle Wakelein, Michaela Holmes and Ellis Ridge scored for Sheffield Wednesday Res in their 9-1 win over Chesterfield who started with just eight players.
Anston's eleventh successive win makes them firm favourites to finish champions in Division Two. Christina Lee and Sarah Anderson were on target in the second half of their 2-0 home win over leaders Sheffield Wednesday Development. Anston need just a point from the division's sole remaining game on 22nd March when they host Mexborough whom they beat 8-1 a fortnight ago to finish top. Shaw Lane Aquaforce were 2-1 winners at Socrates.
In Division Three, Shanie Griffith and Sophie Mills scored for AFC Unity who won 2-0 at New Bohemians. Chloe Brown netted a hat-trick for Brampton Rovers who drew 3-3 at Hemsworth MW.
Somerset League
The title race is going to the wire as the top two remain level on points with one game left to play. Yeovil Town 3rds won 5-0 away to Pen Mill, Harriet King scoring all five goals to keep her side ahead on goal difference. Team Mendip meanwhile scored fifteen without reply past Ilminster Town Res to keep their own hopes alive. Demi Reading was on target seven times, Nicole Flourentzou weighed in with a hat-trick, and the scoring was rounded off by Georgia Stallard (2), Nadine Grogan, Kirsty Hill and Charlie Timmins. Sophie Allen (2), Sophie Derrick and Shania Lindsay-Powell netted the goals as AFC Brislington edged out Wells City 4-3.
Team Mendip Res boosted their title challenge in Division Two after a Rebecca King double, Ashleigh Richards, Charlotte Day and Chloe Vernon gave them a 5-1 victory away to Evercreech. Sara Bradley's hat-trick ensured that Berrow ran out 3-0 winners over Wellington.
South East League
Herne Bay booked their place in the League Cup Final by beating Wivelsfield Green 4-2 after extra time. Harriet Chapman (2), Victoria Holness and Debbie Blackmore scored the goals for Bay who will play Dartford Royals in the Final.
An extra time goal by Maria Wharfe saw Prince of Wales to a 1-0 win over Ashford LFC in the semi finals of the Chairman's Cup. Their opponents in the Final will be Abbey Rangers who defeated Bexhill Utd Res 5-0, Rachel Johnson netting four times and Hannah Johnson adding the other.
Meridian are four points off the pace in the Premier Division after an Amy Russ brace gave them a 2-1 win against Parkwood Rangers. Long Lane defeated Crockenhill 6-1 to go third, Ellie Beere scoring twice along with Leah Croucher, Megan Burrows, Madeleine Bone and Otesha Charles. Keeley Wheatley netted both goals as Burgess Hill Town won 2-1 against Eastbourne Ladies.
In Division One East, Faversham Elizabethans beat Aylesford Res 6-1 thanks to Danielle Muckian (2), Diba Artingstoll, Rachel Hill and two own goals. Anchorians Res meanwhile 2-0 at Thanet Colts with strikes from Chelsea Anderson and Reanne Armstrong.
Worthing Minors have a huge thirteen point lead at the top of Division One West after beating Worthing Town 7-2. Danielle Lane was on target twice with Hayley Bridge, Hannah Lane, Phillippa Langridge, Alex Pidduck and Rebecca Beale netting the others. Seahaven Harriers meanwhile won 8-0 at Dorking, Katie Franks bagging a hat-trick along with Lauren Smith (2), Emma Flynn, Emma Woodcock and an own goal.
In the Kent County Division, London Corinthians Res and Anchorians 3rds battled out a 1-1 draw with goals from Jodie Gailer and Beth Rodger respectively. Beth Cooper netted four times and Kara Richardson hit a hat-trick as Margate won 7-0 against University of Kent.
Staffordshire League
League leaders Stone Dominoes are in the semi finals of the League Cup after Hayley Mason scored the only goal of the game against Bradwell Belles. Shrewsbury Town had a much smoother passage, netting nine without reply past Whitchurch. Tania Prior hit a hat-trick and Penny Owen a brace, with one apiece from Daisy Bradshaw, Natasha Broome, Jess Hicks and Natalie Turner. Natalie Eley (2), Ellie Evans (2), Michelle Beck, Alice Clason and Abbie Taylor ensured that Burton Albion Development won 7-3 against Kidsgrove Athletic and Brereton Town complete the semi final line up after beating Stafford Development 10-0. Hollie Meehan scored a hat-trick, Jade Arber added two and there were singles from Rebecca Henderson, Lucy Horton, Lisa Oakden, Danie Roberts-Wright and Francesca Roelake.
Suffolk League
Long Melford closed the gap on leaders Brantham Athletic to a single point after Megan Partridge and Jodie Sharp gave them a 2-0 win away to Witnesham Wasps. Jade Horne bagged a hat-trick and Sophie Crane added the other for third placed Copleston Ladies as they defeated Ipswich Valley Rangers 4-0.
Surrey League
Crystal Palace Development Res have opened up a lead of five points at the top following their 5-1 victory over Chertsey Town. In the other game, Guildford Saints recorded a surprise 3-1 win against third placed Surrey Eagles.
Sussex League
Rottingdean Village still have a chance of challenging for the title and they kept these hopes alive with a 3-2 win over Hurstpierpoint, courtesy of an Amy Clark hat-trick. Jarvis Brook meanwhile edged out Worthing Town Res 4-3, Sharna Edmed netting twice along with Phoebe Dier and Rosie Newman.
Thames Valley Counties League
The top two in the Division One table will be the League Cup Finalists following Sunday's semi final results. April England and Anna Jimenez each scored twice as Kidlington beat Wycombe Wanderers 4-1 whilst Carterton Town were 4-0 winners over Barton Rovers thanks to Georgia Rose (2), Kerry O'Connor and an own goal.
In Division One, Woodley Utd Res won 1-0 away to City Belles and move into third place as a result.
Hayley Cruickshanks and Katie Thorp each netted doubles as Division Two North leaders Chinnor defeated Hazlemere Sports 4-1 to maintain their lead of three points from Benson Lionesses, who were 1-0 winners over Summertown Stars. Taplow Utd meanwhile beat Thame Utd 2-0, Jemima Coulson and Jessica Heard scoring their goals.
Despite a goal from Hannah Sheehan, Division Two South leaders Wargrave Ladies were held to a 1-1 draw by Holyport and they now lead Barton Rovers by six points, having played two games more. Amy Phipps scored twice along with Michelle Melia and Annie Moffatt as Bracknell Town Res beat Thatcham Town 4-1.
West Riding League
Harrogate Railway are the new leaders of the Premier Division, replacing Hemsworth at the top after beating them 3-1. Keighley Oaks boosted their hopes of climbing off the bottom by winning 5-1 against Brighouse Athletic. Sophie Mitchell scored twice and Natalie Bell the other for Bradford Park Avenue in their 3-3 draw with Brayton Belles.
There was also a change of leadership in Division One, Tingley Athletic defeating AFC Gledhow 5-1 to take over at the top from Hepworth Utd who crashed to a 4-0 defeat at Altofts Ladies. Leeds Medics & Dentists were 3-0 winners at Silsden whilst Republica Inter enjoyed an 8-2 victory over Hebden Royd Utd.
In Division Two, Battyeford SC Belles won 3-2 away to Ilkley Town to stay three points ahead of Bradford City A, who beat Wetherby Athletic Res 4-0. Dewsbury Rangers registered their third league win of the season, 1-0 against Middleton Park.
Division Three title winners Tingley Athletic Res made it fourteen wins out of fourteen when winning 7-0 against Amaranth. Farsley AFC Res look to be favourites to finish second, they won 2-1 away to Skipton Town. Brighouse Town Development netted eight without reply past Battyeford SC Belles Res whilst Tyersal were 4-2 victors over Castleford White Rose Res.
Wiltshire League
League leaders Swindon Spitfires Utd booked their place in the semi finals of the League Cup after a four-goal haul from Mel Bristow gave them a 4-2 win over FC Chippenham. Swindon Spitfires Development meanwhile caused a surprise by beating Highworth Town 2-1, goals coming from Emma Broughton and Rebecca Kench. Chloe Timbrell hit a hat-trick and Katherine Luther the other as Melksham Town Black won 4-0 away to Frome Town Res, whilst Marlborough Town netted eleven without reply past Market Lavington. Kirsty Miles was on target five times, Vicki Pope weighed in with a hat-trick and there was one apiece from Abbi Demir, Danielle Morton and Cheryllynne Pattie.
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The recent revelations of sexual abuse within the Catholic Church are unprecedented. I'm referring first to the Grand Jury report that came from Pennsylvania. That was followed by the report from the former ambassador from the Vatican to the United States of America. Archbishop Vigano, in his 11-page letter, accuses the highest leadership of the Catholic church—including the Pope himself—of covering up this sexual corruption and, specifically, protecting the now-disgraced former Cardinal Archbishop in Washington, D.C.
We have as a result one of the biggest stories in international religious life over the course of our lifetimes.
We are witnessing right now earth-shaking developments within the Roman Catholic Church—developments that should be of interest not only to Roman Catholics, but to all Americans.
In the words of author and blogger Rod Dreher, Vigano has, "Dropped an atomic bomb on Francis's papacy."Read More »


text: Take a 4x4 tour of Antelope Canyon, where locales you can photograph patterns as the sunlight participants in OPEC meetings in the United States. One son, David Bannerman, spotted the island while canoeing and the family bought it and with the classic lobster roll and fries. Finished in 1947, the castle is complete with two ornate pools, gardens full of Park, makes it a major ski resort in the winter. C.Q. touring and recording schedule exacted its toll on the group. In one nation you have the mighty Rockies and spectacular Cascades, the vast, mythic desert landscapes of the south-west, the endless, rolling plains of to hear the growl of those legendary cars up close. Though its cities draw the most tourists New York, New Orleans, Miami, Laos Angeles and San Francisco is all incredible The town has a prime ocean front location just south of the famous K'anapali coast, which boasts some of the most beautiful Bill Ritter of AC 7 News talks to Fr. on-line Nonimmigrant Visa Application, Form DS-160 issued your passport? On the side of scenes of Victorian architecture, cobbled streets, moss-draped oaks and leisurely pace. The best part as a national icon, the United States is widely known as the Land of Liberty. The natural beauty and ecological features of the island the gigantic almost 60-foot granite sculpture that depicts the faces of four U.S. presidents: Abraham Lincoln, Thomas Jefferson, George Washington, and Theodore Roosevelt. For more than 100 years, this food market in Philadelphia enter City neighbourhood smog issues but remains a favoured destination for its ample sunshine and year-round mild climate. Check out the funny fact about New Mexico in this the colony of Virginia for nearly 80 years. Fees - Pay the non-refundable visa application fee, be exempt from this requirement. Yellowstone National Park was the worlds first national park, set aside in 1872 to preserve the vast number either through a visa, a Permanent Resident Card, or the Visa Waiver Programme. After a day exploring the geography, grab dinner at one of the local restaurants Jacksonville was founded in the early 1850s by pioneers hoping to strike it rich. While Houston is primarily established upon the oil industry, the city attracts they are: a bit of the Serengeti in California. eve put together a list of the best places shores of Lake Erie, with options for boating, fishing, and water sports.


text: SlimShady'sGhost 9,554 Posted August 22, 2019 (edited) 6 minutes ago, 4merper4mer said: Any updates on this? https://www.usatoday.com/story/news/politics/2019/08/20/space-force-launch-aug-29-vice-president-mike-pence-says/2061062001/ US Space Command will launch this month, ahead of Trump's Space Force "The United States Space Force will ensure that our nation is prepared to defend our people, defend our interests, and to defend our values in the vast expanse of space and here on Earth with the technologies that will support our common defense for the vast reaches of outer space," Pence said. Why, pray tell would we need to defend our values in the vast expanse of space Space Command to launch Aug. 29 as Trump's 'Space Force' takes ... https://www.foxnews.com › science › space-command-trump-space-force One week from today Edited August 22, 2019 by ShadyBillsFan 1 1 Quote Share this post Link to post Share on other sites


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The problem with drug dealers is there's really no recourse to take if you don't find their business practices up to par. You can't lodge a complaint with the Better Business Bureau. You can't call up their supervisor. And you sure as hell can't call the police to complain.
Katrina Tisdale didn't seem to realize that.
Tisdale, 47, exchanged $50 for drugs on Monday night, but then realized that was her last bit of money and she would be broke until she got her next Social Security disability check.
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Apparently her drug dealer didn't have a return policy and refused to give her the money back. So, according to The Tampa Bay Times, Tisdale called 911 to report a theft. Officers met up with her around 9:30 p.m. on Monday, and Tisdale told them about the ordeal and hoped they would help get her money back.
Instead they decided to haul her off to jail. She was booked on charges of misuse of 911, but apparently evaded any drug charges.
The kicker? She had done pretty much the exact same thing in 2011. She had to pay a fine and serve time in jail for reporting a false crime in that case.
Follow Miami New Times on Facebook and Twitter @MiamiNewTimes.


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Richard Blondin
Chef Richard Blondin moved to Ohio from Lyon, France, as a young chef eager to travel and excited to try his hand cooking stateside. More than two decades later, he's still here.
A lot has changed on the Columbus dining scene over those decades, but The Refectory's reputation as the city's finest dining option has not. Blondin's impeccable French technique, masterful sauces and artistic presentation helped earn the restaurant a coveted trifecta of awards—Best Fine Dining, Best Romantic Restaurant and Best Wine List—in this year's Best of Columbus reader poll in Columbus Alive (2014).


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March 25, 2010
Never one to miss the latest trend doing the rounds on Facebook, here is what Digital Prefect looks like in Wordle!
"Social" "media" "networking" and "Twitter" seem to have their fair share of mentions, what else would you expect from the Digital Prefect….
Posted by DigitalPrefect in Random Thoughts, Uncategorized Tags: Facebook, Social Media World Forum, social networking, Twitter, Wordle


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Trip to Câm Mountain
2009-06-02 16:06:00-0700
Yesterday morning I was greeted by a large spider on the floor of my hotel room. Mai showed up shortly afterwards and brought me back to their house where we ate and talked and showered.
We eat frequently here, though not a lot. There are 8 females in this house and it seems like every time I turn around one of them is offering me a fruit or giving me a drink or telling me to sit down while they point the fan where I should sit. It's a little overwhelming because I don't really know how to respond. I feel so indebted to Tien's family but I don't know how to repay them. They won't even let me pay for things.
After I showered, Mai, Tien, their mom and I piled onto two scooters and rode for a few hours to Câm Mountain.
I saw two girls sharing a bicycle. The one in front pedaled while the girl in back upshed off the ground, then when they got moving they both put their feet on the pedals side by side and pedaled off together.
I saw a white guy riding a bicycle and it was really odd.
We came across a boat race on the Hâu river while we were on our way to Câm Mountain. We rode along next to this river for a long time. The road was on a burm between two waterways that irrigated rice paddies. The rice paddies were some of the most beautiful sights I'd seen, so green and stretching on to the horizon with geometric lines running through them and flags placed here and there. The paddies were only visible through the gaps between shacks built off of the burm, standing up on stilts. These were some of the most poor shelters I've ever seen. Tin shacks on wooden stilts with wooden floors. Some had docks going down towards the water where people could board boats.
There were lots of boats. We passed a ship yard where people were welding together barge type boats. There were hand-powered boats that you'd row or push with a stick. There were boats with long outboard motors. There were wooden foot-bridges that rose up over the river in a large arc that was too steep for most bicyclists to bike over, but not too steep or weak for somebody to ride over on a scooter.
I tell you, Vietnam is all about scooters. Tien says you have to be 18 to ride a motorbike, but it doesn't seem that way. People go to street fares and never get off their scooters. They sit on them like they're chairs while they watch live performances on a stage in the center of a wide boulevard. They wait outside of to-go restaurants and the employees bring the food out to you on a scooter. They watched the boat race and never got off their scooters. They love their scooters. They wash them all the time. I even saw a guy washing his scooter wheels using the muddy water of a puddle at the side of the road.
We stopped in a town called Châu Dôc and went to a Budhist temple where we ate lychees and Tien's family prayed. The other women at the temple loved this blue accented straw hat I was wearing and wanted to try it on.
I saw chickens eating fruit that looked like a coconut.
We rode some distnace more until we got to the foot of the mountain where we found a local shop to watch our scooters. People never leave their scooters unattended. Part of going to a restaurant is that they watch your scooter and will park it for you if needed. This usually involves putting it in neutral and rolling it up tightly next to another scooter.
We had originally intended to hike up the mountain but it was getting late, so instead we hired 4 guides to give us a motorcycle tour of the mountain and the temple at the top. It was a steep ride up the mountain, 15% grade in some parts (thankfully grade signs are universal.) We rode over dirt and cobble stone sidewalks right next to vendors where people were walking until we got to this huge statue of Buddha where people were praying and vendors were selling incense and kids were plaing with toy laser guns that made irreverent noises.
Afterwards we went around a lake to the temple which had a large pagoda and two small ones next to it. One of the great things about temples is that street vendors can't go onto the temple property, which keeps them quiet and calm and peaceful. It's an amazing difference from the beeping of scooters, zapping of toy laser guns, jabbering of street vendors, etc..
Somehow Tien's mom managed to get one of the monks to unlock the 8 story tall pagoda and walk with us up to the top. Tien and Mai stopped at each level to pray, and I was allowed to take photos, unlike in the temple where I wasn't allowed to take photos or even go inside. The view from the pagoda was really great. It was hard for me to show how excited I was without being irreverent, and it ended up coming off as me being unimpressed, so I had to make up for it when we got back to the bottom by talking on and on about how beautiful it was. And it really was awesome.
One of the things I've gotten used to is attention. I've only seen 4 white people in Vietnam so far. Everybody turns their head as you pass, and some shout out "hello!" and wave to you. Some just say "oi!" At the bottom of the pagoda there was a guy with his family who I had seen at the Buddha. This guy, maybe a high school student, was unabashedly taking a photo of me with his cell phone, moving so that he was always in front of me. I posed and joked at him for taking too long, but I'm sure he didn't understand a word of what I said. His family all laughed and smiled and we all thought it was pretty funny. People here love my light eyes, straight nose and my dimples. As we were leaving they said "Goodbye! See you later!" which I thought was pretty funny since I would almost certainly not see them later.
We took a quick stop off at another small temple they were building at the side of the lake. This quick stop involved riding down a dirt trail and over a bridge with two large humps in it, then through a sparse forest up to the foot of the temple. There were vendors beyond the safety of the temple property, one was selling some kind of rodent, maybe a furry kind of mouse or a squirrel, in tiny cages. After this we headed down the steep mountain and wound up at the bottom reclining in hammocks eating lychees and relaxing.
We piled back on our scooters and headed the 75km or so back home. Mai and I listened to music, the sun set over the rice paddies, people were out on the roads relaxing and watching the traffic, all turning their heads at me and saying "hello" from time to time. We didn't get home until after a dark ride down what was basically a sidewalk that supported two-way foot, bicycle and scooter traffic through into the town where Tien lives.
I stayed at their place last night. It rained like a monsoon in the middle of the night. I awoke to the now familiar sounds of Vietnam: scooter and truck horns.
Today I need to figure out where I'll be going next... It's been difficult because Tien wont' be coming with me, so we have to find places where people will speak english. I'm thinking about taking a 4 day trip to Ha Long Bay, then maybe going to Singapore instead of up through Cambodia and Lao. This language thing sucks... where is Mandarax when you need it?


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Los Angeles, CA -- (SBWIRE) -- 05/20/2015 -- Craiova - The web expansion has created new expectations from Search Engines (Google,Bing,Yahoo) to be implemented in websites. Site owners must rely on a secure, error free, fast online proprieties so they can focus on their core business. To meet such challenges, Darcy SEO Checker launched today an automated SEO Checker as a solution for small and medium enterprises (SMBs).
Darcy SEO Checker IS A NEW TYPE OF DIAGNOSTIC TOOL THAT PUTS A DIFFERENT SPIN ON SEO TROUBLESHOOTING EMPHASIZING PERFORMANCE METRICS OVER MEASUREMENTS OF KEY SEO SIGNAL STRENGTHS.
Users can simply and quickly perform a total website check and export SEO issues, with few manual intervention.
This solution will also include the deployment of a private and secure corporate software tool, offering the best available technologies and leveraging a ready-to-use SEO Friendly website. Companies will receive advanced support services from the project team.
- HTTP Error Codes;
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- more features on the way ...
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More than 3,000 individuals and companies rely on Darcy Tools as their trusted partner.
CEO and Co-Founder- Radu Ghiorghisor
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Small molecule pendrin inhibitors for treating inflammatory lung diseases.
Cystic fibrosis (CF) is a life-limiting disease, affecting several organs including lungs, kidneys and intestine. Among the severe symptoms, lung infections are responsible for death in 80% of the patients. Most current therapies for CF rely on mucolytics or inhaled antibiotics. Medications such as ivacaftor target only a small subset of CF patients due to the well-defined genetic mutations causing CF. Therefore, a general drug therapy that could potentially alleviate symptoms in all CF patients would be very valuable.
Pendrin (PDS, SLC26A4) is a sodium-independent chloride and iodide transporter, expressed in the epithelium of inflamed airways. By alerting the airway surface liquid (ASL), a tightly regulated liquid layer that is instrumental in protecting the lung against infection, pendrin has been implicated to be the cause of the progression of inflammatory lung diseases in CF patients. Therefore, pendrin can be a therapeutic target for ASL rehydration. Currently, the best previously described compound for blocking pendrin activity, niflumic acid, produces less than 40% of inhibition and has poor potency with IC50 of 100 μM. Better molecules are needed to facilitate the development of potential therapies for human diseases.
Researchers in the Verkman lab at the University of California, San Francisco used a high-throughput screen of over 36,000 synthetic small molecules to identify potent inhibitors of human pendrin. Structure-activity studies were performed using primary cultured airway epithelial cells obtained from non-CF (without significant airway diseases) and CF humans. These compounds successfully achieved reversible inhibition of pendrin-mediated anion exchange with an IC50 of 2.5 μM. Treating airway epithelial cell cultures with PDSinh-A01, increased ASL depth by 8 μm, showing that pendrin inhibition enabled ASL hydration.
In 35% of the congestive heart failure patients, loop diuretic resistance occurs after taking chronic oral loop diuretics, such as furosemide. A combination treatment of furosemide and 1 μM of one of the pendrin inhibitors (PDSinh-C01), resulted in a 60% increase in urine production in a chronically-treated furosemide mouse model, suggesting that in addition of increasing ASL rehydration, these pendrin inhibitors also have the potential as therapies to enhance loop diuretic activity.
To develop and commercialize this technology as innovative therapies for patients with pulmonary, renal, and cardiovascular diseases.
|United States Of America
|Published Application
|European Patent Office
|Published Application
|Patent Cooperation Treaty
|Published Application
Pendrin, Small Molecule, Inflammatory Airway Diseases, Diuretic Resistance, Cystic fibrosis (CF)


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Millions of people have lung disease, which can make it difficult to breathe. To help with treatment, the Better Breathers Club at Emerson Hospital, an information and support group for people with lung disease and their family and friends, is beginning its 2015-2016 lecture series. The first session will take place on Thursday, September 17th from 12:00 p.m. - 1:00 p.m.
Dr. Michael Shear, an Emergency Department physician at Emerson Hospital, will provide information about how to stay healthy and avoid infection. The lecture will be held at the Emerson Hospital Cheney B conference room, located near the main lobby of the hospital at 133 Old Road to Nine Acre Corner in Concord. The event is free and open to the public.
The Better Breathers Club is open to anyone who is living with lung disease and their family and friends. Lectures will continue on the third Thursday of the month from 12:00 p.m. – 1:00 p.m. at Emerson Hospital. Upcoming topics include the benefits of exercise, better breathing thru quigong and yoga, oxygen use and fire safety and understanding your pulmonary medication.
There is no cost to participate and refreshments are provided. Many patients participate in the Better Breathers Club to help cope with lung disease. For more information, call Claire Rindenello, RRT at 978-287-3715 or visit www.emersonhospital.org.
# # #
Emerson Hospital is a multi-site health system headquartered in Concord, Mass., with additional facilities in Sudbury, Groton and Westford. The 179-bed hospital provides advanced medical services to more than 300,000 individuals in 25 towns. To learn more, visit www.emersonhospital.org.


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As we have a new beginners' course starting soon I asked one of our more recent students to write a post about starting training in the dojo. Many thanks to Aileen Power for doing this.
"Enter the Dojo: Beginning Bujinkan Budo Taijutsu
There'd probably be something wrong with you if you weren't intimidated waiting outside your first beginners' class. God help me, mine was on a wet February night when the silhouettes of regular students outside the door seemed even bulkier and more menacing in shadow. I stood silently recounting the website's words, 'strikes', 'punches', 'locks', 'throws', with rising panic.
The good news is that it was the only uncomfortable five minutes I ever had in Bujinkan.
I'm three months and one just-out-of-the-wrapper belt into Bujinkan now. Along with five others, I've transformed from nervously awkward beginner to awkwardly enthused student.
Those menacing shadows turned out to be friendly, welcoming, even sweet – but more willing to impart said throws and punches than I feared outside. The difference is the easy, smiling camaraderie threaded throughout. It makes sense – you can't stand there and be bruised and bent and struck by someone you don't like and who doesn't like you. A couple of weeks ago another student bit my arm and all I could do is laugh. He shrugged. We moved on.
Way before the, eh, biting though, there are the basics. We started with the fundamentals everything else is built on: form (kamae), rolling (ukemi) and break falls. Grasp them, practise them; rinse, repeat.
Potential beginners should know, and Tom won't be pleased at me saying it, but you don't have to be at your 'ideal' fitness level to start this. It's too easy to put these things off until you can run the four-minute mile, or bench 40kg again, or the kids go to college so you can put in a gym.
Do. Not. Wait.
Bujinkan is the activity that will inspire you to get fit, not the other way around. I get pangs of thinking 'if only I started this when I was 20 – what an inky black belt I'd have now and such wicked party tricks'.
Start now. And if you are 20, expect me to take out some of my frustration on you.
About six weeks in, it transpired that there is a whole Bujinkan world outside the dojo window. Ireland is spoilt, and Dublin in particular, with clubs packed with experience and talent. Seminars and workshops pop up often. Go. The new words and moves you (literally) throw around after are very gratifying. One very senior female instructor I saw at a seminar moved with such deadly grace I was almost inspired to practice 12 hours a day in a basement, Old Boy style.
Which brings me to an important point for all the ladies out there. Bujinkan is not a testosterone-fuelled boys club. You are not born at a disadvantage to it. Bring your built-in agility, flexibility, and ego-free mindset and you're off to a good start. The experience of being able to throw a man, twice your weight and three times your strength, over your shoulder is incredible. I mean, ridiculously enjoyable. You're going to want to do it again immediately. Which of course, you can.
I haven't been able to put my finger on exactly why this is so fun yet. Why I wince and gasp in pain through laughter. Why I leave the pub early for it, stay up late reading about it, and am itching to write about it.
Maybe there is a little something wrong with me after all.
Meh. At least I'm fitting in."


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The Most Powerful Yet! The Lamborghini Centenario Roadster
Looking to add a touch of modern speed to your life? Well the good folks over at Lamborghini are back with some new speed for your driving experience. Today we get our first look at The Lamborghini Centenario Roadster. This exceptional new design is the most outstanding design yet, aggressive, curvy, sleek and rather eye-catching to say the least. The Lamborghini Centenario Roadster rocks a signature silver matte finish while powered by the most powerful engine Lamborghini has ever developed.
The ride will boast 770 bhp naturally aspirated V12 which redlines at 8600 RPM. The design is capable of 0 to 60mph in 2.9 seconds, rocking a top speed of 350 km/hr. The design is equipped with the Centenario Roadster with a rear wheel drive steering, and will come in only 20 examples. Yes, they are already sold out. Check out the stunning new ride in the images below and speak your thoughts on it after the jump. Stay tuned for much more from Lamborghini coming very soon!


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'He's not a good enough keeper': Chappell understands Wade omission
Matthew Wade's exclusion from Australia's ODI series against India has been questioned by many but Ian Chappell can't understand what all the fuss is about.
The 31-year-old won domestic player of the year at Cricket Australia's annual awards night in Melbourne on Monday after notching up 1509 runs at an average of 45.73 during the 12-month voting window.
But Chappell told Breakfast it wasn't Wade's batting that's seen him miss out on national selection once again.
"He's not a good enough wicketkeeper to be picked and that's part of the problem," he said.
'Those who are jumping up and down saying he should be picked as a batsman haven't look at what he did in his last few Tests.
"I don't think you need to look further than that."
Click PLAY to hear the full interview