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Iwakuma shine as M's down Twins
Seattle, WA – Hisashi Iwakuma tossed seven outstanding innings on Friday as the Seattle Mariners topped the Minnesota Twins, 5-3, in the opener of a three-game series at Safeco Field.
One game after Felix Hernandez tossed a perfect game in a 1-0 win over the Tampa Bay Rays, Iwakuma (4-3) retired the first 12 batters he faced before giving up a double to Justin Morneau. He allowed unearned one run on four hits with six strikeouts to notch the win.
Morneau's double snapped a streak of 42 consecutive batters set down by Mariners pitching, going back to the ninth inning of Tuesday's game against Tampa Bay.
"I think it shows how crazy this game is, that's pretty phenomenal for our pitching staff," Jaso said of the streak. "There's a lot of those little things that defy the odds in this game. This game is all about stats and all about averages and you got to go with those, but there's a time when it's going to shock you."
John Jaso ripped a two-run home run and Miguel Olivo clubbed a solo shot, while Eric Thames and Dustin Ackley added an RBI apiece for the M's, who have won three straight.
Joe Mauer and Josh Willingham smacked solo home runs for the Twins, who lost for the third straight time. Nick Blackburn (4-9) took the loss after giving up five runs on 11 hits over 5 1/3 innings.
Seattle got off to a fast start with a pair of runs in the first at-bat as Michael Saunders lined a one-out single to center and scored when Jaso smoked a two-run shot over the wall in right.
Olivo led off the Seattle second with a towering home run deep into the seats in left to extend the margin to 3-0.
Morneau picked up Minnesota's first hit of the contest with a sharp double down the right field line and Ryan Doumit reached on Brendan Ryan's throwing error to put runners on second and third. Matt Carson got the Twins on the board with an RBI single into left-center field, cutting the deficit to 3-1.
Iwakuma got out of the inning by striking out Pedro Florimon Jr. and Darin Mastroianni.
Trayvon Robinson started the Mariners' sixth with a double and scored on a two-bagger by Thames, who advanced to third on a bunt by Ryan and scored when Ackley ripped a base hit up the middle to extend the lead to 5-1.
Mauer and Willingham stroked back-to-back solo shots with two outs in the eighth to pull the Twins within two, but Tom Wilhelmsen turned Minnesota away in the ninth to pick up his 17th save of the season.
"Offensively, we didn't do much," Twins manager Ron Gardenhire said. "We had a couple of home runs back-to-back which got us back into the ballgame which made it interesting, but like you saw they've got a pretty good closer there."
Game Notes
Prior to Friday's game, the Mariners activated pitcher Charlie Furbush from the 15-day disabled list and optioned pitcher Shawn Kelly to Triple-A Tacoma ... Wilhelmsen has allowed just four runs over his last 31 appearances ... The Mariners improved to 20-13 since the All-Star break.


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Monday, December 12, 2011
New Wave Covers For Oldies Lovers - Part 3
Put your hands in your pockets and commence pogo dancing...NOW!
New Wave Covers For Oldies Lovers - Part 3
Elvis section:
1. Dead Kennedys "Viva Las Vegas"
2. Walter Steding "Hound Dog" [Robert Fripp on guitar]
3. John Cale "Heartbreak Hotel" [live, with possibly Brian Eno, Kevin Ayers, Mike Oldfield)
4. Judy Nylon "Jailhouse Rock"
5. Frank Sumatra And The Mob "Telstar"
6. The Plasmatics w/Lemmy "Stand By Your Man"
7. Nurse With Wound "Antacid Cocamotive 93 ["The Locomotion"]"
8. Brian Sands "Baby You're A Rich Man"
9. Dictators "I Got You Babe"
10. Hüsker Dü "Love Is All Around ["Mary Tyler Moore Show" theme]"
11. Talking Heads "Love Is All Around" (live) [The Troggs]
12. Pure Hell "These Boots Are Made For Walking"
13. Ronny "If You Want Me To Stay"
14. The Plugz "La Bamba"
15. Brian Eno "The Lion Sleeps Tonight"
16. Nash the Slash "Dopes on the Water" ["Smoke On The Water"]
17. Implog "On B'way"
18. Hüsker Dü "Eight Miles High"
19. Plasmatics "Dream Lover"
20. The Stranglers "Walk On By"
Thanks to those of you who suggested some of these.
9 comments:
- dj trish said...
- 2:41 PM, December 12, 2011
Why the American Idol karaoke doll with the Devo headpiece? Windbag
- 4:52 PM, December 13, 2011
- Mr Fab said...
The doll was given out by McDonalds to represent the New Wave genre (does American Idle even feature any New Wave?).
Devo was not amused, and sued 'em.
- 4:59 PM, December 13, 2011
I broke up when you explained the doll. American Karaoke is Clive Davis trying to recreate his success with Manilow and Air Supply now some 25 years later, at least on the recording end. I think the closest AM-I has gotten to new wave is Adam Lambert doing a mashup of Boy George & Culture Club as played by an Elvis impersonator (hmmm...inspiration...echoes of Dread Zeppelin?)
McDonald's got zinged back in the '70s for stealing H.R. Puffinstuff's closet for all the live action cartoon characters like Grimace and the Hamburgler, as I recall. Windy
- 2:30 PM, December 15, 2011
- efkos said...
Wendy O Williams cover of "Stand By Your Man" has long been my favorite cover song. She knew how to make any song bad-ass.
- 2:24 PM, December 17, 2011
- Andrew McLean said...
Looks like I've discovered your "New Wave Covers" series too late. Hope you're able to repost them at some point!
- 4:17 PM, March 19, 2013
Hi, can you renew the link to New Wave Covers For Oldies Lovers - Part 3? I just discovered it after your new Covers post, thank you so much!
- 8:30 AM, June 02, 2016
- Bernhard said...
New Wave? Some songs are Punk Rock (Punk), isn't it?
- 1:36 AM, July 27, 2016
- Mr Fab said...
Yes Berhard, but as I recall in ye olden times, the phrase "New Wave" was used to cover all the new music, at least so far as the media and music biz was concerned. I don't recall hearing it specifically mean the less angry/more pop stuff until later in the '80s.
- 9:59 PM, July 27, 2016

subset: commoncrawl


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Product Description
Curved Goggles. Racing Green Leather, Mark 410 Goggles is an inspired design by Brooklands motorcar racing. Crafted with care by Halcyon, for classic car enthusiasts. Join the British Racing Drivers Club (BRDC) and wear these goggles proudly. A fashion which captures the history of 1907.
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Not Just for Classic Car Enthusiasts. Motorcyclists also wear our curved goggles with pride, in celebration for Brookland racing. You don't need a classic car to get involved!
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Nose-Bridge Adjuster. Stainless Steel Knurled adjustment screw allows for a comfortable and secure fit. The fine threaded bolt brings the goggle frames closer together or further apart. Adjust the goggles to fit the contour of the face. One size fits all.
Polycarbonate Lenses. Goggles come with polycarbonate lenses as default. Comes with 99.9% UV protection, scratch resistant coating (Anti-fog, mist prevention lenses). To note: Currently 'Tinted Lenses' are not available for the Mark 410 at this time.
One Size Fits All. Adjustable headband can be worn with open-faced or closed face helmets. Goggles can also be worn without a helmet. Headband elastic is lined with silicone. This feature gives the headband extra grip, when worn over helmets.
Dimensions. 19cm Width x 9cm Height
Meets Road Safety Standards. The brand 'Halcyon' is carefully pressed into the goggle frames, along with the 'BS4110' mark. The BS4110 is the standard safety regulation for protective goggles (For road use). This mark is may also be required for various sporting activities, such as quad bikes.
Tinted lenses? Currently, Tinted Lenses are not available for the Mark 410 Curved goggle range.
International Shipping? We ship world-wide. Dispatching goods outside of the United Kingdom will be no problem. Delivery time approx 7 to 10 days, via Royal Mail, USPS.
Will Goggles Fit My Helmet? Our goggles have been designed for open-faced helmets. On the off chance the goggles do not fit or suit your motorcycle helmet, you may return them for a full refund.
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Can The Mark 410 Goggles Be Worn Over the Top of Glasses? Unfortunately, the goggles are very hit or miss when worn over the top of spectacles. Many of our customers wear our goggles over the top of there glasses. However, we cannot guarantee a comfortable fit. Please feel free to place your order and try, if they do not fit comfortably, you may return them for a full refund. Please don't hesitate to contact our support team for any further information.
Additional Information
Additional Information
|Frame Finish
|Polished Chrome
|Face Mask
|Product Code
|Goggle Mark


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Portsmouth Public Schools special education programs and services are mandated by the Individuals with Disabilities Education Act (IDEA), which requires states to provide free, appropriate education to children with special needs. Because of the challenges associated with implementing effective special education, many federally-funded programs exist to assist schools, teachers and parents in providing children with the highest quality education available.
801 Crawford Street, Portsmouth, VA 23704
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Pharmacokinetics Study of Gamma-aminobutyric Acid (GABA-PK)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01917760
Recruitment Status : Completed
First Posted : August 7, 2013
Last Update Posted : November 2, 2015
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Diabetes Mellitus Diabetes Mellitus, Type 1 Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases Autoimmune Diseases Immune System Diseases
Type 1 diabetes is an autoimmune disease resulting from the progressive loss of pancreatic insulin-secreting beta-cells. This consequently leads to a lack of insulin and elevation of blood sugar, namely hyperglycemia, which is a major cause for the development of diabetes and its acute or chronic complications. The current treatment for type 1 diabetes requires a life-long dependency on daily insulin injections, causing inconvenience and burden to patients. Drug-induced hypoglycemia is also common as it presents a major challenge in insulin therapy. Furthermore, although insulin therapy is lifesaving, it is not a cure as it neither reverses the progression of the disease nor prevents the development of serious complications associated with this disease. New treatments are urgently needed.
Recent studies have demonstrated that a natural chemical found in the brain, gamma-aminobutyric acid (GABA), which is also produced in large quantities by pancreatic beta-cells, has beta-cell regenerative and immunoregulatory effects. Importantly, GABA prevented and partially reversed diabetes in type 1 diabetes mouse models. It is important to address essential questions regarding the potential effects of GABA in diabetic patients in humans. Given the largely unknown mechanism of action of GABA in the pancreas, and the limited information on how GABA is absorbed, distributed and eliminated from the human body, we plan to examine these issues (referred to as pharmacokinetics/pharmacodynamics) in normal subjects.
The outcome of this study will provide useful information on the mechanism of action of GABA in human subjects.
|Study Type :
|Actual Enrollment :
|12 participants
|Time Perspective:
|Official Title:
|The Pharmacokinetics of Gamma-aminobutyric Acid in Healthy Volunteers.
|Study Start Date :
|July 2013
|Actual Primary Completion Date :
|July 2014
|Actual Study Completion Date :
|December 2014
- pharmacokinetic characteristics of γ-aminobutyric acid (GABA) [ Time Frame: baseline and up to 30 days ]
The primary endpoint of this study is to obtain the pharmacokinetic characteristics of γ-aminobutyric acid (GABA), including:
- Area under the plasma concentration-time curve from time 0 to the last quantifiable concentration (AUC0-t),
- Area under the plasma concentration-time curve from time 0 extrapolated to infinity (AUC0-∞),
- Maximum observed plasma concentration (Cmax),
- Time to maximum plasma concentration (Tmax), and
- Terminal elimination half-life in plasma (t½)
- serological characteristics [ Time Frame: baseline and up to 30 days ]plasma glucose levels, insulin, C-peptide and glucagon levels will be measured
- Exploratory measures [ Time Frame: baseline and up to 30 days ]plasma glucagon-like peptide-1 (GLP-1) and glycated serum protein (GSP)will be measured.
Biospecimen Retention: Samples Without DNA
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|19 Years to 40 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Inclusion Criteria:
- Volunteers in good health condition between 19 and 40 years of age (inclusive) at the time of signing the informed consent.
- Body mass index (BMI) between 18.5 and 24 kg/m2 (inclusive), with weight greater than 50 kg.
- Not on any medication 2 weeks before screening.
- No blood donation within 3 months before screening.
- Must sign the informed consent. Note: Blood and biochemical tests must be normal during the screening. However, if the participant's test-results were beyond the normal range, the individual can still be recruited as long as the results do not affect the experiment.
Exclusion Criteria:
- Abnormalities of physical examination, laboratory tests, or ECG in screening, which may influence the results of the study.
- Previous or existing history of severe heart, liver, kidney, gastrointestinal, nervous system, mental, or metabolic abnormalities as well as other diseases which can affect drug absorption, circulation, metabolism, or excretion.
- History of alcoholism, smoking, or drug abuse within the past 1 year.
- Participation in any clinical drug study within the past 30 days.
- Any definite or suspected allergy or family history of allergy to GABA or any other similar drugs.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01917760
|China, Shanghai
|Department of Endocrinology and Metabolism,Huashan hospital
|Shanghai, Shanghai, China, 200040
|Principal Investigator:
|Yiming Li
|Huashan Hospital
|Principal Investigator:
|Qinghua Wang
|Huashan Hospital/St Michael's Hospital
|Principal Investigator:
|Zheng Jiao
|Huashan Hospital
|Responsible Party:
|Zhaoyun Zhang, professor of endocrinology and metabolism, Huashan Hospital
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
JDRF_17-2013-499 ( Registry Identifier: Juvenile Diabetes Research Foundation International (JDRF)] )
|First Posted:
|August 7, 2013 Key Record Dates
|Last Update Posted:
|November 2, 2015
|Last Verified:
|October 2015
Gamma-aminobutyric acid
Diabetes Mellitus
Diabetes Mellitus, Type 1
Metabolic Diseases
Glucose Metabolism Disorders
Autoimmune Diseases
Immune System Diseases
Endocrine System Diseases


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Uwe Neumeier, Vice President Global Server Business, Fujitsu
"Over the last 20 years, Fujitsu PRIMERGY servers have helped to shape ICT, while setting new standards in quality, efficiency and agility. The new PRIMERGY generation is no exception and introduces innovations that contribute to solving data center management challenges. Customers choosing PRIMERGY can be confident that they are buying a system which provides modular building blocks for future requirements of a business-centric data center."
Shannon Poulin, Vice President, Data Center Group, Intel
"The new Intel® Xeon® processor E5-2600 v3 product family provides PRIMERGY servers with an incredible combination of performance, built-in capabilities and cost-effectiveness. Together with Fujitsu's many server innovations, they provide customers with highly efficient, record-performing server solutions to address the diverse workloads and rapidly evolving needs of today's data centers."
Shaun Walsh, Senior Vice President Marketing, Emulex
"Emulex and Fujitsu have developed a new model for network I/O with the modular design of the Fujitsu PRIMERGY DynamicLoM architecture based on the Emulex EngineTM (XE)100 series Ethernet controller. This solution delivers application acceleration with RDMA over Converged Ethernet (RoCE), scales new workloads with up to a 4x boost in small packet performance, lowers operational cost with hardware offloads and provides the right I/O roadmap for next generation servers using the Intel Xeon processor E5-2600 v3 family."
Highlights of the new generation of PRIMERGY include:
20 years of FUJITSU Server PRIMERGY Systems:
The Fujitsu x86-server portfolio has been helping to shape the ICT industry for 20 years. During that time, Fujitsu has concentrated on using its technology to solve customer' technology issues. Thanks to continuous adaptation to industry trends and a continually evolving ICT landscape, Fujitsu has developed new approaches to cloud computing, data analytics and high performance computing. Some milestones:
2 For terms and conditions, please see: http://www.fujitsu.com/20years-primergy
3 Based on Fujitsu shipments from the 2013 calendar year, calculated on the basis of 250 working days each made up of 8 hours.
4 PRIMERGY RX2540 M1 achieved 16,000 SD benchmark users on the two-tier SAP SD standard application benchmark. The server was configured with Intel Xeon processor E5-2699 v3, 2 processors / 36 cores / 72 threads, Windows Server 2012, SQL Server 2012, and the SAP enhancement package 5 for the SAP ERP 6.0 application. The SAP certification number was not available at press time. Benchmark comparisons stated above reflect results published on http://www.sap.com/solutions/benchmark/sd2tier.epx as of September 08, 2014. SAP and all SAP logos are trademarks or registered trademarks of SAP AG in Germany and in several other countries.
5 The VMmark result of 26.48@22 tiles was achieved by two Fujitsu PRIMERGY Server RX2540 M1, each with 512 GB of memory, using Intel® Xeon® E5-2699 v3 processors. Full test results including system specification, further details and current results can be found at: http://www.vmware.com/a/vmmark/.The comparison reflects the status on September 8, 2014. For information about VMmark and the rules regarding its usage visit: http://www.vmware.com/products/vmmark. VMware and VMmark are trademarks or registered trademarks of VMware, Inc. VMware® VMmark™ is a product of VMware, Inc.
6 Comparison based on two-tier SAP Sales and Distribution (SD) standard application benchmark: PRIMERGY RX300 S8 featuring Intel® Xeon® processor E5-2697 v2, 2 processors/24 cores/48 threads, achieved 10,240 benchmark users (Windows Server 2012, SQL Server 2012, SAP enhancement package 5 for SAP ERP 6.0, certification 2013024) while the PRIMERGY RX2540 M1 featuring Intel Xeon processor E5-2699 v3, 2 processors/36 cores/72 threads, achieved 16,000 benchmark users4.
Fujitsu is the leading Japanese information and communication technology (ICT) company offering a full range of technology products, solutions and services. Approximately 162,000 Fujitsu people support customers in more than 100 countries. We use our experience and the power of ICT to shape the future of society with our customers. Fujitsu Limited (TSE: 6702) reported consolidated revenues of 4.8 trillion yen (US$46 billion) for the fiscal year ended March 31, 2014. For more information, please see http://www.fujitsu.com.
In Continental Europe, the Middle East, Africa and India, Fujitsu is the leading IT infrastructure provider with a presence in all key markets serving large, medium-sized and small businesses. The company offers a full portfolio of IT products, business solutions and services, ranging from workplace systems to datacenter solutions, managed services, and cloud-based software and solutions. In CEMEA&I Fujitsu employs approximately 13,000 people and is part of the global Fujitsu Group. For more information, please see: ts.fujitsu.com/aboutus.
All other company or product names mentioned herein are trademarks or registered trademarks of their respective owners. Information provided in this press release is accurate at time of publication and is subject to change without advance notice.
Godeke HarrackFujitsu Technology Solutions GmbH
Phone: +49 89 62060 3479
E-mail: firstname.lastname@example.com
PR Manager International Business
OnPR GmbH
Phone: +49 89 30 90 51629
E-mail: email@example.com
Date: 09 сентября, 2014
City: Munich


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