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Volodymyr H. Hryn, Yuriy P. Kostylenko, Valentyna P. Bilash, Olena B. Ryabushko
Ukrainian Medical Stomatological Academy, Poltava, Ukraine
Introduction: The small intestine of albino rats is a transitive canal between the stomach and the cecum that is closely located from each other, reaches a length of one meter, which in comparison ratio to body weight significantly exceeds the corresponding segment in humans.
The aim: The paper is aimed at thorough histological study of the wall and structure of albino rats' small intestine mucosa.
Materials and methods: 30 mature albino male rats were involved into the study. The specimens of albino rats' small intestine, fixed in 10% neutral buffered formalin solution, have been studied. The study was carried out using conventional histological methods for obtaining serial paraffin sections stained with hematoxylin-eosin. Epoxy plastination of individual tissue samples of the small intestine was performed. Subsequently, polished thin sections were made, stained with 1% methylene blue and 1% borax solution. The obtained specimens were studied on the "Konus" light microscope equipped with Sigeta DCM-900 9.0MP digital microphoto attachment with the Biorex 3 software adapted for studies of such type.
Results and conclusions: For the first time in the practice of histological study of the epithelial covering of the mucous membrane of the small intestine, attention is drawn to the specific pattern of its organization on the intestinal villi. It has been found that epithelial covering consists of alternating cluster epithelial aggregations separated by fissured depressions. Since no mentioning about them has been found in the publication, these cluster aggregations of enterocytes can be called epithelial buds of the intestinal villi.
Consequently, it can be concluded that with the exception of some specific morphological features, the small intestine of albino rats is homologous to human one by its histological structure, which means that it can be used as a model for various experimental studies.
KEY WORDS: small intestine, epithelial buds, enterocytes, albino rats
Wiad Lek 2019, 72, 5 cz. I, 733-738
The small intestine of albino rats is a transitive canal between the stomach and the cecum that are closely located from each other, reaches a length of one meter, which in comparison ratio to body weight significantly exceeds the corresponding part in human [1, 2, 3, 4, 5, 6, 7]. However, publications report that they are considered to be completely homologous by the histological structure of their wall, which proves the validity of the experimental modeling of the pathological processes of the small intestine on albino rats [8, 9, 10]. And yet, with a more demanding approach to the data available in the literature, a number of questions arise that cannot be neglected when trying to increase the reliability of the findings of experimental studies and, thus, verify the extrapolation of their validity to human one.
The paper is aimed at thorough histological study of the wall and structure of albino rats' small intestine mucosa.
30 mature albino male rats weighted 200,0±20,0 g were involved into the study. The specimens of albino rats' small intestine, fixed in 10% neutral buffered formalin solution, have been studied. Euthanasia of rats was made under thiopentone anesthesia overdose (75 mg / kg animal body weight intramuscularly in the upper third of the hip of the hind paw) [8, 11].
Before the experiment, all animals were kept in standard conditions of the experimental biological clinic (vivarium) at the Ukrainian Medical Stomatological Academy in compliance to the regulations on keeping experimental animals adopted by the European Parliament and Council Directive (2010/63 / EU), the Order of the Ministry of Education and Science, Youth and Sports of Ukraine as of 01.03.2012, No. 249 "On approval of the procedure for conducting tests, experiments on animals by research institutions" and "General ethical principles of experiments on animals", adopted by the V National Congress on Bioethics (Kiev, 2013), (Minutes No. 155 as of 26.04.2017 of meeting the Commission on Biomedical Ethics at Ukrainian Medical Stomatological Academy) [12, 13, 14].
The study was carried out using conventional histological methods for obtaining serial paraffin sections of 4 µm thick (Microm HM 325), stained with hematoxylin-eosin. Additionally, methods of epoxy plastination of individual tissue samples of the small intestine were used. Subsequently, polished thin sections were made, stained with 1% methylene blue and 1% borax solution [15, 16, 17]. The obtained specimens were studied on the "Konus" light microscope equipped with Sigeta DCM-900 9.0MP digital microphoto attachment with the Biorex 3 (serial number 5604) software adapted for these studies. Morphometric studies were performed using the system for visual analysis of histological specimens.
Considering the great length of above region of the gastrointestinal tract of albino rats, it is possible to restrict studying of the autopsy material to only three of its selected portions, namely, 1) the duodenum; 2) small intestine between the Peyer's patches and 3) in the zone of Peyer's patches localization.
The findings of the study has established that the wall of the albino rats' duodenum consists (if not considering the finest outer covering in the form of adventitia or serous membrane) of only two membranes, namely, mucous and muscular. In this regard, the first one is about three times thicker than the second one (Fig. 1). If the muscular layer is a simple uniform layer (about 10 layers) of the fusiform smooth myocytes, then the mucous membrane is rich in content of various structures, but among them entirely muscle plate is located. Consequently, its lamina propria is directly associated with the muscular layer, i.e., in the wall of the duodenum of albino rats the submucosa does not exist at all, in contrast to human one. Therefore, all the glandular structures of the mucous membrane, such as the crypts of Lieberkühn and the Brunner's glands, are entirely localized in its lamina propria. It has long been known that the first of them are tubular invaginations of the epithelium, originating between the intestinal villi and extend down into the lamina propria (in albino rats this corresponds to the border with the muscular layer). These formations are notable for the Paneth cells contained in their walls, which produce the anti-microbial enzyme lysozyme (muramidase), which is commonly assigned to the humoral factors of the innate (nonspecific) immunity. Interestingly, scarce intraepithelial lymphocytes reside among the Paneth cells at the basal portion (Fig. 2). Notably, in the duodenum of albino rats, crypts of Lieberkühn also serve as the excretory ducts for the mucous Brunner's glands, entering them, the acini of which are in the form of compact glomeruli between the basal portions of the crypts and the muscular layer.
In contrast to the proliferated (invaginated) crypts, the mucous membrane of the duodenum forms numerous villous projections, which, among other similar formations of the small intestine, are characterized by a variety of shapes and large sizes. Figure 3 shows that such formations are bushy-branched, so that a common base and a number of short branches can be identified in each villus. They are based on connective tissue papillae, which are derivatives of the lamina propria of the mucous membrane, covered with simple columnar epithelium. Compacted bundle of collagen fibers is located in their axial position, surrounded by a fine-fiber network of reticular fibers, containing predominantly lengthwise amorphous substance, within which blood microvessels of the capillary type are found. Publications report that no lymph vessels of the appropriate caliber are found in the duodenal villi. Noteworthy, this interstitial space, occupying the place between the axial connective tissue induration, and the covering epithelium is abundantly infiltrated by the lymphocytic elements.
It is known that the epithelial covering of the mucous membrane of the small intestine is monostratal. However, its description, available from the publications, does not entirely coincide with the observed pattern during the study of histological specimens, on which the covering epithelium of the intestinal villi is not uniformly organized. Magnified microimages clearly show that it has an uneven, tuberous relief on its external surface, due to the fact that the components of its epitheliocytes are distributed in separate cluster aggregations, which are separated by fissured depressions (Fig. 4). Since no mentioning about them has been found in the publication, these cluster aggregations of enterocytes can be called epithelial buds. Each epithelial cluster consists of a certain number of high (columnar) cells, located very close to each other, the borders between which, even in higher magnifications of the light microscope, can hardly be identified. They are better identified by their nuclei, which, being in a row, form a kind of twisted chain that repeats the form of convex surfaces of epithelial buds and depressions between them. Due to the fact that the intestinal epitheliocytes are closely interconnected, their brush borders form a continuous common coating on the convex surfaces of the epithelial buds, interrupting only in the zones of fissured depressions between them. It is well known that the brush borders of enterocytes are formed by numerous microvilli in the form of finest projections of the apical plasmolemma. Such type of increasing the area of the plasma membrane is characteristic of cells carrying out transmembrane transport of substances. This suggests that in the duodenum, the process of absorbing the products of hydrolysis of high molecular nutrients is performed in the zone of free surfaces of epithelial buds, whereas in the zones of fissured depressions such process cannot occur because of the absence, according to the findings of the research, of brush borders. Therefore, the question arises about the role of these depressions in the digestive process of the duodenum. However, it is not known whether such a structural organization of the intestinal villi epithelium is peculiar in other laboratory animals, and, moreover, that it is particularly significant in humans. To date, no solution to such issues has been found.
Essential formations of the mucous membrane of the mesenteric part of the small intestine of albino rats are represented by innumerable intestinal crypts, residing in the lamina propria and bordering its basal portions with the muscular layer. Their shape and cytological composition are similar to the aboveglands of Lieberkühn, which, as in the duodenum, open with narrow orifices between the villi. In contrast to latter, the mucous (Brunner's) glands are not found in the rest of mesenteric portion of the small intestine. Apparently, their absence is compensated by the diffuse distribution of mucous cells among the epithelial cells of the intestinal villi, which are variable in shape, but of the same type in their internal structure. It should be noted that they differ from similar formations of the duodenum by the presence of centric lymphatic microvessel in their connective tissue, around which connective tissue is diffusely infiltrated by the cells of the lymphocyte series, from the mass of which migration of individual lymphocytes to the covering epithelium is noted (Fig. 5). Moreover, among these cells, sporadic transverse and oblique profiles of blood microvessels are found. Furthermore, the intestinal villus of the covering epithelium is organized in the form of cluster aggregations that can be called epithelial buds, similar to duodenum ones, though sporadic mucous cells are found among their prismatic columnar epithelium (in contrast to the duodenum).
In addition, solitary lymphoid nodules are found in the intermediate zone of the small intestine between the Peyer's patches in an irregular order. Noteworthy, these lymphoepithelial formations, occupying the entire thickness of the mucous membrane, are surrounded by typical intestinal villi, being circumferentially connected with the basal portions of crypts. At the same time, the bases of these nodules are directly adjacent to the muscular layer, whereas their apical surface is covered with similar columnar epithelium, forming the small villi, which are not mentioned in the publications. Since the objective of our prospective investigations is the experimental study of the nature of structural changes in the lymphoid aggregations of the mucous membrane of the albino rats' gastrointestinal tract in the effect of antibiotics to its microflora, a more detailed description of their single and grouped nodules in its small intestine will be presented in the subsequent publications.
The small intestine is the longest part of the digestive tract, intended to perform the major functions in the process of the consumption of nutrients by the body, which are mainly products of enzymatic hydrolysis of proteins, fats and polysaccharides. The final phase of this process is the absorption of these nutrients into the internal environment of the body. The conveyor nature of digestion in the small intestine is generally expressed in the well-known anatomical distinguishing of such parts as the duodenum, jejunum and ileum, the length of which in a human is approximately (separately) is 30 cm – 2 m – 3 m, respectively. Evidently, the length of the rat small intestine is much smaller. However, the data reported in the literature are questionable. Thus, according to them, the length of the rat duodenum is comparable to that of a human one, and the rest of its small intestine is approximately equal to 1 meter. Consequently, the entire rat small intestine is only by 4-5 times shorter than that of a human one. Obviously, in a limited volume of the rat abdomen of such a length, the digestive tube can fit if it is sufficiently thin [18, 19]. Unfortunately, no data on its thickness have been found in the literature to date. It is known, the transverse size of the human small intestine varies in length from 2 to 3 cm [2, 4].
The mucous membrane of the human small intestine, preserving its general principle of the structure, has not only its own distinctive features, but also differs in certain morphological features in its various parts. A common anatomical feature for it is the presence of numerous transverse-ring folds throughout it, due to the loose submucosa and smooth muscle tone. But their number and degree of manifestation gradually decreases towards the distal part of the ileum. In the duodenum, the folding of the mucous membrane is somewhat different in that from the side of the medial wall of its descending part where a permanent longitudinal fold is located, which inferiorly becomes higher and ends with a large papilla. It opens with one common hole of the bile duct and pancreatic duct. A little superiorly, the second papilla of a smaller size is located, on which the accessory pancreatic duct opens.
The mucous membrane of the small intestine, in the straightened state, is distinguished by a dull, velvety appearance, due to the numerous tiny (about 1 mm long) finger- or foliate processes called the intestinal villi [20, 21, 22]. The mucous membrane of the small intestine has a greatly developed local representation of the immune system in the form of intestinal lymphoepithelial clusters called lymphoid nodules. Mostly they are in the form of single nodules and their group clusters [9, 10, 23].
1. The wall of the small intestine of albino rats, in its entire length (about one meter) from the pyloric part of the stomach to the place of the entering to the cecum, consists of two, most pronounced, coaxial membranes, namely, mucous and muscular, which are not separated by a well-marked submucosa.
2. The essential basic structures of the entire intestinal tract of albino rats are simple tubular (Lieberkühn) glands, i.e. intestinal crypts, which in the duodenum, along with their particular secretory properties, serve as excretory ducts for the acini of the mucous (Lieberkühn) glands located between the muscular layer and the lamina propria of the mucosa.
3. The orifices of intestinal crypts are distributed regularly along the mucous membrane surface, being hidden in depth between the intestinal villi, the size of which steadily decreases in the caudal direction while maintaining, as is known from the publications, the typical principle of structural organization.
4. For the first time in the practice of histological study of the epithelial covering of the mucous membrane of the small intestine, attention is drawn to the specific pattern of its organization on the intestinal villi. It has been found that epithelial covering consists of alternating cluster epithelial aggregations separated by fissured depressions. Since no mentioning about them has been found in the publication, these cluster aggregations of enterocytes can be called epithelial buds of the intestinal villi.
Consequently, it can be concluded that with the exception of some specific morphological features, the small intestine of albino rats is homologous to human one by its histological structure, which means that it can be used as a model for various experimental studies.
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16. Kostilenko Yu, Boyko I, Starchenko I і dr. Metod izgotovleniya gistologicheskih preparatov, ravnotsennyih polutonkim srezam bolshoy obzornoy poverhnosti, dlya mnogotselevyih morfologicheskih issledovaniy [Method for making histological preparations equivalent to semi-thin slices of a large viewing surface for multi-purpose morphological studies]. Morfologiya. 2007;132(6):77-82. (Ru).
17. Mal'kov P, Frank G, Moskvina L i dr. Osnovy obespecheniya kachestva v gistologicheskoy laboratornoy tekhnike: Rukovodstvo [Fundamentals of quality assurance in the histological laboratory equipment: Guide]. Moskva: GEOTAR-Media. 2011. – 108 р. (Ru).
18. Hryn V, Kostylenko Yu, Yushchenko Yu et al. General comparative anatomy of human and white rat digestive systems: a bibliographic analysis. Wiadomości Lekarskie. 2018; tom LXXI, nr 8:1599-1602.
19. Nagwa E. Effect of High Fat Diet on the Structure of the Ileum of Adult Female Albino Rat and The Role of Concomitant L-arginine Treatment. Light and Scanning Electron Microscopic Study. Egyptian Journal of Anatomy. 2016;39(2):1-17.
20. Gusejnova S, Gusejnov T. Anatomija struktur slizistoj obolochki tonkoj kishki belyh krys [Anatomy of the structures of the mucous membrane of the small intestine of white rats]. Sovremennye naukoemkie tehnologii. 2010;8:140. (Ru).
21. Yuldashev А, Kakhkharov Z, Nishanova A. Оsobennosti strukturno-funktsional'nogo stanovleniya dvenadtsatiperstnoy kishki i brunnerovykh zhelez krys v ranniy postnatal'nyy period zhizni [Features of the structural and functional formation of the duodenum and brunner glands of rats in the early postnatal period of life]. Sovremennyye problemy nauki i obrazovaniya. 2009;3:77-80. (Ru).
22. Ermund A, Schütte A, Johansson M et al. Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches. American journal of physiology. Gastrointestinal and liver physiology. 2013;305(5):341-347. doi: 10.1152/ajpgi.00046.2013.
23. Umoren E, Osim E. Morphology of the Small Intestine of Albino Wistar Rats Following Long Term Administration of Nevirapine. Biochem Pharmacol. 2014;3:132-137. doi:10.4172/2167-0501.1000132.
The paper has been written within the research scientific work, carried out at the Department of Human Anatomy of the Ukrainian Medical Stomatological Academy, entitled "Age-related aspects of the structural organization of the organs of the human immune system, glands of gastrointestinal and urogenital system in normal condition and pathology"; State registration number 0116U004192.
Authors' contributions:
According to the order of the Authorship.
Conflict of interest:
The Authors declare no conflict of interest.
Volodymyr H. Hryn
Department of Human Anatomy
Ukrainian Medical Stomatological Academy
Shevchenko 23 str., 36011 Poltava, Ukraine
tel: +380668126497
e-mail: email@example.com
Received: 11.03.2019
Accepted: 26.04.2019
Figure 1. The wall of duodenum of albino rat. Paraffin section; H&E stain;
4× magnification.
1 – muscular layer; 2 – mucous membrane; 3 – intestinal villi.
Figure 2. Microscopic structure of the wall of albino rat's duodenum. Paraffin section; H&E stain; 40 × magnification.
1 – muscular layer; 2 – acini of the mucous (Brunner's) glands; 3 – blood microvessels; 4 – basal portions of the crypts of Lieberkühn; 5 – lymphocytic infiltration of the connective tissue.
Figure 3. Villous projections of the albino rat's duodenal mucosa. Epoxy slice in tangential section; methylene blue stain; 2× magnification.
1 – villi of the mucosa; 2 – inner lumen.
Figure 4. The structure of the villus of the duodenal mucosa. Paraffin section; H&E stain; 40× magnification.
1 – epithelial buds; 2 – nuclei of prismatic, columnar epithelial cells; 3 – fissured depressions between epithelial buds.
Figure 5. The villus of albino rat's small intestine. Paraffin section; H&E stain; 40× magnification.
1 – muscular layer; 2 – the basal portions of the intestinal crypts; 3 – epithelial buds; 4 – mucous cells; 5 – lymphocytic infiltration of the connective tissue base of intestinal villus; 6 – lymphatic vessel.


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See K. Hakuta, Mirror of Language: The Debate on Bilingualism (1986); J. Cummins and D. Corson, Bilingual Education (1997); and H. Kloss, The American Bilingual Tradition (1998). On English studying measures, they reported that forty five percent of the findings had been inconclusive, while 22 p.c of the transitional bilingual education schemes outperformed structured immersion, and 33 p.c of the structured immersion applications (primarily the Canadian French Immersion programs) outperformed transitional bilingual teaching programs.
The Bilingual Education Act was terminated in 2001 by new federal education policy, with the passage of No Child Left Behind by the U.S. Congress This regulation offers no help for native language learning, however quite emphasized accountability in English solely, and mandates that all students, together with ELLs, are tested yearly in English.
Those who support a bilingual strategy, says Arizona Superintendent of Instruction Thomas Horne, aren't concerned about educating the youngsters English," however need to maintain a separatist nationalism that they'll benefit from." Horne, a Republican, intervened with the state's GOP legislative leaders to try to undo the federal court injunction.
Although bilingual training within the context of charter colleges is mostly seen as a instrument that aids in reaching rigorous academic outcomes for English language learners as well as native English speakers, additionally it is considered as ensuring equal access to opportunity and fostering optimistic cultural identity and shallowness, which might be linked to academic success.
Last year, 17 years after California (followed by Arizona and Massachusetts) started its assault on bilingual schooling, California state Senator Ricardo Lara launched a bill in the California legislature, lately accredited, to put a proposition on the 2016 California ballot that would give college students more entry to bilingual and even multilingual instruction.

subset: commoncrawl


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June 27, 2017
New measures to stop microbusinesses being locked into expensive rollover contracts were put in place today.
The Competition and Markets Authority (CMA) concluded a two-year long investigation in June 2016. They found that around 45% of micro-businesses across Britain were on their energy supplier's costly default tariffs.
One of the CMA's recommendations was that suppliers have to stop locking small companies into automatic rollover contracts and that they have to make it easier for them to compare the cheapest energy prices. They have to do this by ensuring information is clearly available on the supplier's website, or via a link to a price comparison website.
Energy firms are now required to comply with the CMA's recommendation and had until yesterday to make to get the information live on their websites.
Dermot Nolan, Ofgem Chief Executive said:
"This is a big change in the way the market works.
We'll be working closely with suppliers to make sure they give micro-businesses clear information on the prices they offer in line with the regulation. We are considering what further steps could be taken to protect and help these business customers engage in the market as part of our wider programme to make sure all consumers - business and domestic - get a better deal."
The CMA expects the remedies to help micro-businesses save up to £180 million a year.
Smaller firms will also be able to leave more expensive auto-rollover default tariffs without having to pay exit fees.
As advocates for transparency and fair pricing, Energylinx for Business welcome these changes. You can find the best supplier for your business online or by calling one of our advisors on 01259 225400.
Posted on June 27, 2017 at 03:15 PM


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Editor's note: We have confirmed that Jeffrey Epstein owned a modeling agency where he brought girls in from Slovenia to be used to seduce and blackmail wealthy and powerful men, according to a new MSM story, on behalf of Israeli intelligence. We also know that it was Jeffrey Epstein that introduced Melania to Donald, something confirmed in the MSM story below. Are those things connected?
Connecting "dots" or more than dots, much more, involving Trump, Epstein and Israeli control of Trump can and we believe has been fatal.
Our people like Melania, say she hates Donald. Imagine that!
We aren't saying that Melania, who is from Slovenia and came to the US as a model, with a history of questionable films, a history erased by plastic surgery and extremely aggressive action in her home country….
We aren't saying that at all but we are saying that the Maxwell/Epstein organization was a Mossad operation, which is confirmed here, based on statements during Acosta's confirmation hearings. From the Daily Beast:
"Is the Epstein case going to cause a problem [for confirmation hearings]?" Acosta had been asked. Acosta had explained, breezily, apparently, that back in the day he'd had just one meeting on the Epstein case. He'd cut the non-prosecution deal with one of Epstein's attorneys because he had "been told" to back off, that Epstein was above his pay grade. "I was told Epstein 'belonged to intelligence' and to leave it alone," he told his interviewers in the Trump transition, who evidently thought that was a sufficient answer and went ahead and hired Acosta. (The Labor Department had no comment when asked about this.)
By "intelligence," they meant "Israeli intelligence," of course. What they forgot to mention is that his target was the United States.
Maxwell came from a Mossad family, they murdered her father in 1991 for trying to blackmail them. We could never find what Epstein actually did for a living and we looked really hard. We start with him leaving college without a degree and getting a teaching job from current Attorney General William Barr's father at an exclusive school…though he had no degree, teaching experience, certification…and was even then an extreme risk at the Dalton School, one awash with sex abuse intrigues.
Then comes Les Wexner…and we begin seeing the moves toward 9/11, war with Iraq and an economic collapse in 2008….but this story is from today's Daily Beast:
"Donald Trump once hosted a party with a guest list made up of just himself, Jeffrey Epstein, and "28 girls," according to The New York Times, and ignored an organizer's warning about Epstein's conduct. The "calendar girl" event is reported to have taken place at Trump's Mar-a-Lago in 1992.
George Houraney, who ran American Dream Enterprise, claimed in an interview that he organized the event after a request from Trump. "I arranged to have some contestants fly in," said Houraney. "At the very first party, I said, 'Who's coming tonight? I have 28 girls coming.' It was him and Epstein." Houraney added that he warned Trump about his friend's conduct, recalling: "I said, 'Look, Donald, I know Jeff really well, I can't have him going after younger girls.'… He said, 'Look I'm putting my name on this. I wouldn't put my name on it and have a scandal.'" The Times report also claims Epstein has told people since the election that he was the one who introduced the president to his third wife, first lady Melania Trump. The White House didn't respond to the newspaper's request for comment."
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Hi there!
If you are interest in working with me so you can learn how to heal your metabolism and lose weight naturally, click here and let's talk about my 1-1 coaching program.
If you are interested in making an appointment for therapeutic body work or infrared sauna therapy, please use the form below.
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Opened 14 years ago
Closed 14 years ago
#493 closed Enhancement (Fixed)
Sounds when in the foreground
|Reported by:
|Dan <theyranos A@…>
|Owned by:
|Colloquy (Mac)
|2.2 (Mac)
|sound notification audio foreground background window focus
Could you add an option to turn on audio notifications for channels that are the foreground window? I have multiple computers, and all my communication programs (Colloquy, Adium, Thunderbird) are on one that I don't generally look at unless it makes a noise.
Several times, I've said something in a channel that I never leave, then left that channel in the foreground, gone and did something else on a different machine, then glance at this machine 1/2 hour later and see that someone has since responded, wondered why I was ignoring them, gotten indignant, and signed off. :)
Change History (3)
comment:1 Changed 14 years ago by Me again
- Severity changed from minor to trivial
- Version changed from 2.0 (2D16) to Latest Nightly
Just checked... This isn't in the nightly build, either.
Fortunately, with two copies of this program running, one of them is always in the background, so I can hear stuff no matter what's in the foreground :)
It would still be nice if this could be accomplished with only one running copy, though.
comment:2 Changed 14 years ago by anonymous
- Owner changed from timothy to anonymous
- Status changed from new to assigned
comment:3 Changed 14 years ago by timothy
- Resolution set to fixed
- Status changed from assigned to closed
Fixed in [3269].


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50% OFF! - Miss Peach FWP Bundle
By Kathryn Estry
Related Products
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Product Categories
Product Information
- Type: Bundle Pack
- Designer: Kathryn Estry
- Software Category: Everyday
- Download Size: 517.7 MB (approximate)
Design Elements
- Digital Papers: 56
- Page Elements: 131
- Monograms Characters: 235
Terms of UseKathryn Estry's Terms of Use for this kit.
How do you know what Terms of Use a kit has?
Look in the lower right corner of the kit preview for one or more of the following icons.
|Personal Use
|Scrap 4 Hire
|Commercial Use
Designer Notes
Every little missy loves pretty colors. Miss Peach is ready to bring her favorite colors, her flower garden, and her pets to your scrapbook pages. This collection will work for all the little missies in your life, and it's huge, so make sure to see all of the coordinating packs. Buy my Miss Peach Bundle at 50% off and get the Scalloped Pack FREE!


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It is a 00 gauge layout based upon an imaginary joint GWR/SR market town junction with a racecourse nearby, somewhere in the West Country and set in the quieter days of the 1930's era...! It currently measures about 17'0" long by 8'0" wide with a depth of 1'9" in most sections. It is now located in my converted garage, which has been fully insulated, etc., as this was too small to take my car...! Not too difficult a decision to make..... I just needed to ensure that I had enough funds to finance the project....!
This layout came about in 1997, when Jill, my late wife (an equestrian), spent two mornings each week riding out and exercising several horses, after I had retired from riding...! To be fair, I used to have horses and ride out with her on a regular basis for over 15 years, but there came a time when my back suffered too much, and I stopped riding horses. It did not take long before I decided to build Brewston...!
For those interested, the baseboards are constructed of 2" x 1" prepared softwood in an open framework style, with a 12mm plywood top covered with 6mm 'Foam Cor' board. All is set on one level with supporting legs about 4'0" high, and permanently fixed at the back to the walls. In those earlier years, it measured about 14'0" by 6'0".
Brewston started out as a simple 'terminus to traverser' layout, but soon changed, when Jill suggested that she would like to see trains 'running around'....! That lead to some modifications, and also adjusting the traverser to then deal with an inner branch line. even though supportive at a distance) still made some very good suggestions to improve the layouts appearance....!
Sadly, Jill passed away in 2008, following a brief illness, and I then decided to move to a smaller home. Until this move, Brewston had been located in a spare room at my workshop in Surrey. With help from a friend, the layout was dismantled and moved to its new home in the 'converted' detached garage. This move presented me with another challenge, as the layout needed extending both ways to make the best use of the space available. Three of the four corners were retained with the fourth being reconstructed. The traverser was replaced with a 'lift out' section located within a new fiddle yard along one long side of the layout, which also allowed easy access to the room. Both ends had their lengths extended and the station complex was lengthened with additional track and points, giving better operational running of both passenger and goods trains. I was left with one corner requiring new landscaping, and decided to create a new halt terminus with cuttings behind it that lead to the fiddle yard area. In this way, continuous running could be maintained, and separate branch line trains could still run at the same time.
Many of the model railway layouts, that can be seen at club shows, are sparsely populated and Jill suggested that I could create a busy 'market day' scene, with locomotives having crews and coaches having passengers. If you have attempted this detailing work, you will know how difficult and time consuming that it is, but the finished result is well worthwhile....!
A real model railway is never finished, and I'm sure that some further minor 'modifications' will happen in due course....!
Brewston is dedicated to my late Jill, who not only gave me the confidence to create it, but also helped me, over the years, to 'pay attention' to the many details that a model railway requires....! Not bad for an equestrian lady...! Real 'Soul mates' are rare to find, but I was very privileged to have spent those years with Jill.
My sincere thanks go to a great 'bunch of experienced '4 mm / 00 gauge modellers' who are the members of the Twickenham & District Model Railway Club (formed in 1961) for all of their support and encouragement in progressing this layout.
Finally...... pictures ...... thanks to Carol, my Sister-


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Plan Description
Comfortable family living. This spacious rambler allows for 3 bedrooms, 2 bathrooms, and a large open concept living area with a fireplace, an island and walk-in pantry, along with a laundry and mudroom all on one level. A covered deck off the dining room provides flexible entertaining options. A large lower level can be finished to add 2 additional bedrooms, a bath, a large family room and plentiful storage. A large 3 car garage completes the list of needed features for today's family home.
Plan Features
- 1,662 sq ft finished living space on main (3,324 total sq ft w/optional basement finish)
- Contemporary open concept living area w/cathedral ceiling
- Recessed lighting in living room
- 3 bedrooms, 2 baths on main floor
- Custom cabinets throughout house
- Kitchen island w/pendant lighting
- Granite or quartz kitchen countertops
- Walk-in pantry
- Large mudroom/laundry area filled with lockers and cabinets
- Tray ceiling in master suite
- 5 pc master bath
- Window seat in front bedroom
- Linen closet in hall bath
- Covered rear deck
- 3-stall garage w/floor drain and 8' overhead doors
- Room for 2 additional bedrooms, bath, spacious family room, and large storage room in optional finished basement
Floor Plans (2)
First Floor


text:
Country Manager in Germany
Proračun $15-25 USD /uro
Greetings from Your Word,
We are a 24/7 Professional Translation Company with presence in several countries looking to expand all across Europe. We provide Professional Translation, Localization and Interpretation services in more than 70 Languages. Legal, Financial, Medical and Technical Translations are only some of our best services. Candidates who know how a company like this perform activities are highly desirable.
Job Description.
We are currently seeking to recruit qualified candidates for our Country Manager position, this a full time remote job to be done in several Countries. Candidates from Germany, Netherlands, Italy, Spain and France are highly desirable (not limited). The ideal candidate is the one who will be able to work remotely, handle sales/cold calls, overcome difficult secretaries/receptionists, reach the actual key player of a certain company even at "busy times", offer our services professionally and close a sale even for exigent clients.
All candidates must be willing to have a long-term collaboration with us and also have Translation Services Background (not limited but highly desirable).
Desired Profile.
• 4 or more years of experience as a Sales Manager (or related)
• Excellent English Communication Skills
• Bachelor's degree in Business, Marketing, Communications, or related field.
• Proven ability to meet and exceed sales quotas
• Proven track record of successfully managing customer relationships
• Excellent interpersonal skills
• Highly self-motivated
• To be proactive, self-confident and able to close sales.
• Proficient in Microsoft Office
• Prospect and qualify new sales leads over the phone.
• Track all sales activities in company CRM system and keep current by updating account information regularly.
• Maintain a well-developed pipeline of prospects.
• Develop strong, ongoing relationships with prospects and customers
• Meet and/or exceed quotas.
• Coordinate with other team members and departments to optimize the sales effort.
Please include "Your Word" at the top of your proposal so we are completely sure you carefully read the job description.
Best Regards
3 freelancerjev ponuja povprečno za $27/uro na tem delu
I am specialize in marketing & design and excited for the opportunity to work with you in accomplishing your goals. I am Good at English (UK), German, Human Resources, Management, Sales. YWRecruitment could you please Več
Your word Hello I would love to explain my position in points : 1) I have 7 years of experience in sales and marketing 2) I am from india and I think India is the best market for your business because india comes s Več


text:
- Large Detached 4 Bedroom Bungalow Set On 1 Acre
- Refurbished And Extended In Recent Years
- High Quality Triple Glazed Windows And Doors
- Fully Fitted Bathrooms With Walk In Showers, Vanity Units And Rain Head Showers
- High Quality Interior Doors And Ironmongery
- Spacious And Light Filled Accommodation
- Detached Garage With Insulated Walls And Floors
- Ample Parking Space To Side, Front And Rear Of The House
- Architecturally Designed To Take Advantage Of The Views Over The Garden And Surrounding Countryside
Exceptional 4 bedroom detached architecturally designed bungalow extending to approx. 155 Sq M (1668 sq Ft) and set on a large plot of approx. 1 acre. The property also benefits from having a large detached garage.
This superb home has been totally refurbished and extended in recent years and is in new condition.
The property has not been lived in and affords discerning purchasers the opportunity to put their own ideas and finishing touches to the property.
The house has been finished to the highest standards and achieves a B2 Energy Rating (with an opportunity to easily upgrade to an A rated home).
Features include high quality triple glazed windows and doors; high quality tiling provided; fully fitted bathrooms with walk in showers, vanity units and rain head showers; high quality interior doors and ironmongery.
The spacious and light filled accommodation has been architecturally designed to take advantage of the views over the garden and surrounding countryside.
Accommodation comprises entrance hallway with hotpress, guest WC, large kitchen, dining and living room, utility room, 4 double bedrooms with 2 ensuite bathrooms and a main family bathroom.
The gardens are laid out predominantly in grass and are bordered by mature trees and hedging. There is ample parking space to the side, front and rear of the house.
Timber gates greet you upon arrival at the property and have the capability for electric gates to be installed as the necessary cabling has been provided for.
The detached garage includes insulation in the walls and floors and could be converted to living space subject to the necessary planning permission.
BER Details
BER: B2 Energy Performance Indicator:116.89 kWh/m²/yr
Entrance Hallway
Fully tiled flooring, alarm control system, hotpress with storage and water cylinder, attic access.
Kitchen/Dining/Living Room
Large open plan room with glazing on three sides, sliding door to patio, vaulted ceiling with roof windows, tiled floor, open fireplace suitable for stove
Utility Room
Ample space for fitted units, plumbed for washing machine and dryer, tiled floor, door to the rear garden
Guest WC
Tiled floor, WC and vanity unit
Main Bathroom
Vanity unit, walk in shower with rain head shower fitting, WC and attractive tiling.
Master Bedroom
Large and spacious room with tiled floor, patio door to rear garden, stainless steel wall lights.
Ensuite - Master Bedroom
Fully tiled, heated towel rail, vanity unit, WC, walk in shower with rain head shower fitting.
Bedroom 2
Double bedroom with new carpet flooring.
Ensuite - Bedroom 2
Fully tiled, heated towel rail, vanity unit, WC, walk in shower with rain head shower fitting.
Bedroom 3
Double bedroom with new carpet flooring
Bedroom 4
Double bedroom with tiled floor and patio door to the garden.
Viewing Details
By Appointment Only
Property Agent
- REA Halnon
- The Avenue, Gorey, Co. Wexford
- 05394 11720
- PSRA Licence No: 005289 /


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Calgary Fire Department fights large blaze downtown
Shortly before noon today, the Calgary Fire Department was called to a fire in a downtown four story building under construction. 911 received multiple calls due to the amount of fire and smoke visible. First arriving fire crews were told there was nobody in the building therefore determined that the most appropriate firefighting tactic was to protect the exposures and fight the fire defensively. A second alarm was quickly called and additional firefighting resources were brought to the scene as needed. Fire crews used aerials, elevated platforms and master streams to fight and contain the fire. A residential building near the fire was evacuated as a precaution. No injuries have been reported as a result of this fire and Calgary Fire Department Fire Investigators are on scene to determine the origin and cause. Traffic in the area has been affected in a several block radius and commuters are urged to avoid the area.


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Motorola's Moto G is one of the best selling smartphones this year from Motorola India . The device is powered with 4.5-inch HD Display , 1 GB RAM , Android KitKat OS , 5 MP Primary Camera etc.
Today , you can buy Moto G with a discount of Rs 2000 from Flipkart . The device has got a Rs 2000 price cut on both of the Moto G models (8GB and 16GB) for a limited time.
The Moto G with 8GB storage can be bought for Rs 10,499 and the Moto G with 16GB can be bought for Rd Rs 11,999.


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The World This Week: October 29th, 2018
Sub Saharan Africa
Zimbabwe has announced its intention to continue its multi-currency regime despite the economic crisis it is currently facing. The country began this practice in 2009 and shortly after began experiencing hyperinflation, which made the local currency worthless. Zimbabwe currently has the United States dollar, the South African rand and local bond notes in its basket of currencies. The Botswana pula and British pound have in times past been accepted as legal tender.
Ethiopia's new president Sahle-Work Zewde has joined the ranks of African women that are leading history as pioneers and leaders in male-dominated spheres. Her appointment on Thursday followed Prime Minister Abiy Ahmed appointing a gender-parity cabinet that included 10 female ministers out of 20. The African Union chairperson, Moussa Faki Mahamat, commended Ethiopia and Rwanda for taking strides to demonstrate that men and women are equal in politics.
At least nine people were injured when a 30-year-old woman detonated a bomb she was holding in Tunisia's capital, Tunis. Describing the blast as a "terrorist explosion," the interior ministry said the woman had had no previous known militant background. Eight of those hurt in the explosion on Avenue Habib Bourguiba, which runs through the middle of the city, were police officers.
Latin America and The Caribbean
Congressman Jair Bolsonaro was announced as the 38th president of Brazil in a contentious runoff election Sunday. Bolsonaro secured 47% percent of the vote in the first round and had 56% of the vote as of Sunday night. He will be sworn in on New Year's Day, but is expected to get right to work with acting President Michel Temer. Bolsonaro is only the second presidential candidate ever nominated from his Social Liberal Party (Partido Social Liberal).
Mexico had a 4-day public referendum over construction at Benito Juarez International Airport in Mexico City. Incoming president, Andres Manuel López Obrador, vehemently decried the project during his campaign due to concerns of corruption and waste. The project, however, is already a one-third completed and is expected to be the third largest airport in the world. Nevertheless, Lopez Obrador vowed to cancel development if it is rejected by voters.
This week is the 36th International Havana Trade Fair (FIHAV). Over 50 countries and numerous business representatives will be attending the annual event to promote free trade and foreign investments within Cuba and the Caribbean. The event will coincide with the 2nd meeting of the Cuba-Russia Intergovernmental Commission on Trade, Economic, Scientific and Technical Cooperation. Several Russian news outlets have stated that Cuba will sign agreements at the events to purchase over $50 million in Russian military equipment.
East Asia and the Pacific
On Friday, Sri Lankan President Maithripala Sirisena removed his party from the ruling coalition and ousted his prime minister, appointing in his place former president Mahinda Rajapaksa. The move has sparked a constitutional crisis as the former prime minister has insisted that only the parliament can make such a decision. During his time as president, Rajapaksa was credited with ending the 27-year civil war with the separatist Tamil Tigers, but also accused of using heavy-handed tactics to do so. These include-human rights violations, and the United Nations estimates 40,000 civilians died in the last days of the conflict. Rajapaksa also moved the country closer to China during his tenure and borrowed heavily from Beijing to fund massive infrastructure projects in line with the Belt and Road initiative. This included a $1.2 billion port which Sri Lanka had to hand back to China last year because it couldn't service its debts. Rajapaksa was voted out of office in 2015 over abuse of power charges.
On Wednesday the U.N. Security Council was briefed for the first time ever by a human-rights envoy on a specific country. The report involved the ongoing crisis of Rohingya Muslims in Myanmar who have faced repression and genocide in a campaign which began in 2015. Over 400,000 Rohingya remain in the country. The envoy called on the council to refer Myanmar to the International Criminal Court (ICC) or create an ad hoc international tribunal. He also recommended an arms embargo and targeted sanctions against the six senior army officials who commanded the violations. Russia and China attempted to block the discussion on the grounds that human rights are outside of the council's mandate. The briefing comes amid the annual meeting at the U.N. when country-specific human-rights reports are presented to the 15-person General Assembly committee that oversees human-rights affairs. A procedural vote to allow discussion in the committee passed with nine nations in favor. U.S. ambassador to the U.N. Nicki Haley has condemned the atrocities but not commented on specific courses of action.
Middle East and North Africa
While initially denying any involvement in the case, this week the Saudi Arabian government claimed the Saudi journalist Jamal Khashoggi died in a "rogue operation." The Saudi public prosecutor contradicted this claim saying the murder was "premeditated." While Turkey is attempting to extradite 18 individuals back to Turkey who were involved in the case, Saudi Arabia says the case will be investigated and tried in Saudi Arabia.
Some of Iran's top oil buyers are reticent to comply with President Trump's sanctions against Iran that are set to begin on November 5. India, China, and Turkey are all worried that there are not enough oil supplies to replace those that will be lost with the Iran sanctions. The price of oil hit a four year high this month, hovering just below $87 a barrel. Some are worried renewed sanctions with Iran could create an even larger global oil price spike.
After being closed for six years, Syria has reopened part of its national museum in Damascus this week. The museum evacuated most of its collection after the museum was closed in 2012 due to the ongoing civil war. Syria has also seen increased tourism from Jordanians since the Syrian-Jordanian border reopened on October 15. For some, it is the first time making the trip from Jordan to Damascus since the conflict erupted in 2011.
South Asia
A political crisis is underway in Sri Lanka following the collapse of the ruling coalition. President Sirisena has dismissed Prime Minister Wickremasinghe, replacing him with Rajapaksa, a Buddhist nationalist who was ousted from the Presidency in 2014. Wickremasinghe maintains that he remains Prime Minister and has disputed the constitutionality of the President's actions. Despite the dispute, President Sirisena has begun to transfer the privileges of the Prime Minister's office to Rajapaksa. The United States has urged all sides to follow the constitution while China has shown early support for Rajapaska's nascent premiership. Rajapaksa has a difficult relationship with the United States. As President, he brutally ended Sri Lanka's 27-year civil war in a military action that may have cost 40,000 Tamil civilians their lives. In the aftermath of the civil war, Rajapaksa relied heavily on China to finance reconstruction, creating a heavy debt burden for Sri Lanka in the process.
Pakistan Prime Minister Imran Khan successfully secured a $6 billion emergency aid package from Saudi Arabia, as Pakistan struggles with falling foreign currency reserves and a widening trade deficit. Saudi Arabia's support will allow Pakistan to pursue a smaller loan from the IMF with less stringent requirements. Prime Minister Khan will travel to China this week, where he will try to secure a loan from China as well. Imran Khan will also likely try to renegotiate the $60 billion China-Pakistan Economic Corridor, hoping to place more emphasis on the need for social development.


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Before the kids head back to school, why not celebrate the end of summer?
Hub City Kids and The Farmer's Table are hosting The Big Scoop: Ice Cream Churn-Off and Back to School Bash 4-7p.m. Friday, Aug. 9.
The free event will take place at 149 S. Daniel Morgan Ave.
Local vendors and businesses will be on-site to showcase kids programs, workshops, hands-on activities, hobbies and sports. Vendors will be coming from Croft State Park, East Main ARTs, Spartanburg County Public Libraries, MAD Music, Generation Kid Strong, Hearts of Clay, YMCA, Spartanburg County 4-H, Spartanburg Science Museum, and Spartanburg Martial Arts.
An ice cream churning contest will take place that you can compete in or you can vote for your favorite.
You can also decorate a high chair with graffiti. There will be face painting, balloons, and musical entertainment.
To enter the ice cream or graffiti contest, call 864-582-6554 or email firstname.lastname@example.com.
Razor Sharp Barbershop will be offering free back to school haircuts from 11 a.m. until 5 p.m. Sunday, Aug. 18 at their shop at 405 John B. White Blvd.
This is the fifth year the barbershop has offered a shape up or all even cut for students.
Call 864-308-1951 for more information.
The FR8yard, 125 E. Main St., is hosting a free family movie night 7-9 p.m. Wednesday.
"The Neverending Story" will be shown as part of the FR8yard's GR8 Flicks series. The movie, which is rated PG, is free.
Have some information, or a group you'd like to highlight in The Huddle? Have a question you'd like us to answer or a joke you'd like to share? Email us at email@example.com.


text: Step-by-step. my boat build resembling the amazing curves of the riva range. all plans were self thought of from my imagination, self draw and self cut. Very high quality stick and tissue flying model for rubber, co2 or electric power. a true scale model with nice detail. features quality die-cut balsa parts, plastic. Model airplane and boat kits engineered to perfection and laser cut by stevens aeromodel. we cater to novice and intermediate builders! your modeling success begins.


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Basketball Play - "Demon"From the Coach's Clipboard Basketball Playbook... lots of great basketball stuff. Come on - join today.
Coach Sartini
Here's another play submitted by Coach Sar. As in any play, adjust the player positions on the floor to fit your personnel. If you have a talented big man who can jump and get above the rim, this play could result in an "alley-OOP", back-side dunk or lay-in.
See Diagram A.
O1 dribbles into the forecourt with O5 trailing. Meanwhile, O2 drives his/her man to the low block and O3 runs baseline off a screen from O4.
O1 passes back to O5. O2 comes up the lane and makes a hard cut out to the wing. It is important that O2's cut takes him/her above the free-throw line extended for a better passing angle for the eventual lob pass.
See Diagram B.
O4 moves up to the ball-side elbow - free throw line area and will set a back-screen. O5 passes to O2, makes a V-cut and goes around O4's back-screen to the hoop (weak-side). After O5 clears the screen, O4 rolls off the screen down to the ball-side block (see Diagram C). O1 replaces O5.
Here are the options:
1. The high lob, back-door pass to O5. The pass goes above the rim to the backside of the hoop where O5 can jump and either dunk it, or lay it in. (This will take some practice between O2 and O5 to perfect the timing and trajectory of the pass).
2. O2 can pass to O4 posting on the block.
3. O2 passes to O3 in the corner.
Helpful DVDs:
Basketball Set Plays
There are many DVDs of set plays in the Coach's Clipboard Basketball DVD Store... too numerous to list here. Areas covered include man and zone plays, out-of-bounds plays, endline and sideline sets, and end-of-game plays. There are DVDs with special plays for motion offenses, 4-out 1-in offense, 1-4 high offense, flex offense, pick and roll offense, and others.
Special Situations & Inbounds Plays
Many more basketball DVDs at the Coach's Clipboard Basketball DVD Store In additon to many baseline and sideline out-of-bounds plays, some of the greatest basketball coaches today stress the importance of special situations that can often determine the outcomes of close games. Situations discussed include: Opening tip, free-throw situations, end of shot clock, end of half, down with under two-minutes and inbounds plays.


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This position is part of the Joint Chiefs of Staff. The incumbent will serve as an INFORMATION MANAGEMENT SPECIALISTLearn more about this agency
As a INFORMATION MANAGEMENT SPECIALIST at the GS-0301-13 some of your typical work assignments may include:
- Provides program management for one or more of the Records and Research Branch's areas of responsibility that include, but are not limited to, Records and Information Management, Discovery and Litigation support, Preservation Orders, Directives and Forms, archiving and research, Library Science, and/or other assigned program responsibilities.
- Provides technical advice, guidance, and assistance for the development and maintenance of electronic information management systems, coordination of projects, and development of technology to enhance the operations for the assigned area of responsibility.
- Recognize and recommend business/process/systems solutions to problems and potential problem areas that have significant impact on information management plans, programs, schedules, etc.
- Serves as a leader in the field of systems/technology/ infrastructure/innovations supporting the information management program and as a resource to the DOD staff, federal sector, and vendor community when appropriate.
- Analyze and evaluate new approaches and methodologies proposed by the academic, industrial, defense, and other government agencies for possible inclusion in Joint Staff information management program development plans and programs.
- Represents the Joint Staff on information management policy and related issues in meetings with the military departments, other governmental agencies, private industry, and academia.
- Serves as a member on specific policy and records management policy related work groups for coordination and compliance with policy and doctrine, providing leadership for these work groups and chairmanship as required.
- Provides excellent customer service to support Joint Staff missions that meets or exceeds customer expectations and contributes to their success. Achieve excellence in customer service by providing timely, accurate and professional service at each and every customer contact, maintaining customer service metrics.
- Support the mission of the RRB by consistently serving customers in a manner resulting in extreme satisfaction or delight.
- Performs other duties as assigned.
Travel Required
Occasional travel - You may be expected to travel for this position.
Supervisory status
Promotion Potential
Job family (Series)
Conditions Of Employment
- Must be a U.S. citizen
- Males born after 12-31-59 must be registered for Selective Service
- Resume and supporting documents (See How To Apply)
- Suitable for Federal employment, determined by a background investigation
- May be required to successfully complete a probationary period
- Work Schedule: Fulltime
- Overtime: Occasionally
- Tour of Duty: Flexible
- Recruitment Incentives: Not Authorized
- Fair Labor Standards Act (FLSA): Exempt
- Financial Disclosure: Not Required
- Telework Eligibility: This position is telework eligible
QualificationsYou may qualify at the GS-13, if you fulfill the following qualifications:
A. One year of specialized experience equivalent to the GS-12 grade level in the Federal service:
- Providing program management in the areas of Records and Information Management, Discovery and Litigation support, Directives and Forms, Archiving and Research Library Science in accordance with Federal recordkeeping and guidance from the National Archives and Records Administration.
- Using analytical methods regarding information management process changes, technological and business improvements, and industry trends to implement change and experience.
- Analysis of statutory and regulatory processes and controls associated with federal information management programs and administration to provide program management, policy development to improve operations and gain efficiencies.
Substitution of education may not be used in lieu of specialized experience for this grade level.
Additional information
Selective Service Requirement: Please visit http://www.sss.gov for more information.
For more information, please visit General Application Information and Definitions.
Other Notes:
Re-employed Annuitant: This position Does not meet criteria for re-employed annuitant. The DoD criteria for hiring Re-employed Annuitants can be found at:
Status candidates must meet time-in-grade requirements (52 weeks at the next lower grade level).
All applicants must meet qualifications and eligibility criteria by the closing date of the announcement.
Interagency Career Transition Assistance Programs: This program applies to employees who have been involuntarily separated from a Federal service position within the competitive service or Federal service employees whose positions have been deemed surplus or no longer needed. To receive selection priority for this position, you must: 1) meet ICTAP eligibility criteria; 2) be rated well-qualified for the position with a score of 85 or above; and 3) submit the appropriate documentation to support your ICTAP eligibility. For more information:
Males born after 12-31-59 must be registered or exempt from Selective Service (see https://www.sss.gov/RegVer/wfRegistration.aspx
How You Will Be Evaluated
We will review your resume and supporting documents, to ensure you meet the basic qualification requirements. We will evaluate each applicant who meets the basic qualifications on the information provided and evaluate your relevant work experiences as it relates to fundamental competencies, identified below, required for this position.
- Administration and Management
- Communications and Media
- Information Management
Based on the results of this evaluation, you will be placed in one of the following quality categories:
Best Qualified: This highest category will be used for those candidates who possess the type and quality of experience that substantially exceeds the minimum qualifications of the position, including any selective placement factors and/or appropriate quality ranking factor(s), as determined by the job analysis.
Highly Qualified: This higher category will be used for those candidates who possess the type and quality of experience that exceed the minimum qualifications of the position, including any selective placement factors and/or appropriate quality ranking factor(s) as determined by the job analysis.
Qualified: This lowest category will be used for those candidates that meet the minimum qualifications of the position, including all selective placement factors and appropriate quality ranking factor(s) and are proficient in some, but not all, of the requirements of the position. Candidates may require extensive training and/or orientation in order to satisfactorily perform the duties of the position.
Names of the candidates in the Best Qualified category will be sent first to the hiring manager for employment consideration. Applicants in other categories will be referred in accordance with category rating procedures.
Veterans Preference: If you are entitled to veterans preference, you should indicate the type of veterans' preference you are claiming on your resume. Your veterans' preference entitlement will be verified by the employing agency. If you are entitled to veterans' preference and qualified for the position, your name will be placed above non-preference candidates on a list sent to the hiring manager for employment consideration. Qualified veterans' preference eligible with a service-connected disability of 10% or more will be listed at the top of the highest quality category depending on the position and grade level of the job.
For information on entitlement see http://www.fedshirevets.gov/job/vetpref/index.aspx .
Background checks and security clearance
Security clearance
Required Documents
To apply for this position, you must provide a complete Application Package which includes:
1. Your Resume listing work schedule, hours worked per week, dates of employment and duties performed. If multiple resumes are submitted by an applicant, only the last resume submitted will be reviewed for the qualifications and referred for selection consideration if eligible.
2. Other supporting documents:
- Cover Letter, optional- College transcript(s), if qualifying based on education. We accept unofficial transcripts, as long as they contain the applicant's name, the name of the school, the date and degree that was awarded, and the list of classes and credits earned. Transcripts must be received in this office by 11:59 P.M. EST on 06/19/2018 in order to be considered.
- Most recent SF-50 or equivalent notification of Personnel Action showing you are in a position eligible under an interchange Agreement.
- Most recent Performance Appraisal, if applicable
- DD-214, SF-15 Form and VA letter, or certification of expected discharge or release from active duty from Veterans for consideration under Veteran hiring authorities
- Non-competitive appointment authority documentation, if applicable
- Interagency Career Transition Assistance Program Documentation, if applicable (e.g. Certification of Expected Separation, Reduction-In-Force Separation Notice, or Notice of Proposed Removal; SF-50 that documents the RIF separation action; and most recent performance appraisal.)
PLEASE REVIEW the following LINK for additional documents you need to provide: Supporting Documents
If you are relying on your education to meet qualification requirements:
Education must be accredited by an accrediting institution recognized by the U.S. Department of Education in order for it to be credited towards qualifications. Therefore, provide only the attendance and/or degrees from schools accredited by accrediting institutions recognized by the U.S. Department of Education.
Failure to provide all of the required information as stated in this vacancy announcement may result in an ineligible rating or may affect the overall rating.
A career with the U.S. Government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding.
Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time, or intermittent. Contact the hiring agency for more information on the specific benefits offered.
How to Apply
To apply for this position, you must complete the online application and submit the documentation specified in the Required Documents section below.
The complete application package must be submitted by 11:59 PM (EST) on the closing date to receive consideration.
- To begin, click Apply Online to access an online application. Follow the prompts to select your USAJOBS resume and/or other supporting documents. You will need to be logged into your USAJOBS account or you may need to create a new account.
- You will be taken to an online application. Complete the online application, verify the required documentation, and submit the application.
- You will receive an email notification when your application has been received for the announcement.
- To verify the status of your application, log into your USAJOBS account, https://my.usajobs.gov/Account/Login, select the Application Status link and then select the More Information link for this position. The Application Status page will display the status of your application, the documentation received and processed, and your responses submitted to the online application. Your uploaded documents may take several hours to clear the virus scan process.
Agency contact information
DE Applicant Inquires
AddressJoint Chiefs of Staff
Joint Staff
Washington, DC 20318
Mission Statement: The Joint Staff assists the Chairman of the Joint Chiefs of Staff in accomplishing his responsibilities for the unified strategic direction of the combatant forces; their operation under unified command; and for their integration into an efficient team of land, naval, and air forces. The Joint Staff is composed of approximately equal numbers of officers from the Army, Navy and Marine Corps, and Air Force. In practice, the Marines make up about 20 percent of the number allocated to the Navy.
Visit our careers page
Learn more about what it's like to work at Organization of the Joint Chiefs of Staff, what the agency does, and about the types of careers this agency offers.
Next steps
Once you successfully complete the application process, you will receive a notification of receipt. Your application package will be reviewed to ensure you meet the basic eligibility and qualifications requirements, and you will receive a notification. A review will be made of your online questionnaire and the documentation you submitted to support your responses. A list of qualified applicants will be created and sent to the selecting official. All applicants reviewed and/or referred will receive a notification letter.
A list of qualified applicants will be created and sent to the selecting official. All applicants reviewed and/or referred will receive a notification letter.
The selecting official may choose to conduct interviews, and once the selection is made, you will receive a notification of the decision.
Fair & Transparent
The Federal hiring process is setup to be fair and transparent. Please read the following guidance.
Equal Employment Opportunity Policy
The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy And gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor.
Reasonable Accommodation Policy
Federal agencies must provide reasonable accommodation to applicants with disabilities where appropriate. Applicants requiring reasonable accommodation for any part of the application process should follow the instructions in the job opportunity announcement. For any part of the remaining hiring process, applicants should contact the hiring agency directly. Determinations on requests for reasonable accommodation will be made on a case-by-case basis.
A reasonable accommodation is any change in the workplace or the way things are customarily done that provides an equal employment opportunity to an individual with a disability. Under the Rehabilitation Act of 1973 the Equal Employment Opportunity Commission (EEOC) must provide reasonable accommodations:
- An applicant with a disability needs an accommodation to have an equal opportunity to apply for a job.
- An employee with a disability needs an accommodation to perform the essential job duties or to gain access to the workplace.
- An employee with a disability needs an accommodation to receive equal access to benefits, such as details, training, and office-sponsored events.
Legal and regulatory guidance
This job originated on www.usajobs.gov. For the full announcement and to apply, visit www.usajobs.gov/GetJob/ViewDetails/502128500. Only resumes submitted according to the instructions on the job announcement listed at www.usajobs.gov will be considered.


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Want Froyo? Well if you have the Samsung Epic 4G on Sprint, the Samsung Captivate on AT&T, or the HTC Desire, Samsung Acclaim or Samsung Mesmerize on U.S. Cellular, you might just be in luck. Various reports across the web have the Android OS 2.2 update ready for your device, or at least just a little bit closer.
A source of AndroidCentral has said to expect the Froyo update for the Epic 4G on the Sprint network to surface on February 21st. I don't know what the current build of that device is, but the source claims that Samsung insiders already have an Epic running build EA17. Of course this is only a rumor for now, with the "update" just over a week away, so keep your eyes peeled.
Info gathered from a screenshot of AT&T's support page shows a Samsung Captivate running Froyo. Whether this is just a cruel joke or a hint of what's to come, Froyo can be seen in the support information showing how to find your operating system and firmware version. As for if and when, that's still up in the air.
If you're a customer of carrier U.S. Cellular, the HTC Desire, Samsung Acclaim, and Samsung Mesmerize are ready for Froyo. If you own a Desire you can head right over to the official US Cellular page to get the download going now. As for the Mesmerize, build EA11 has shown up, with download instructions available over at XDA Developers.
Source: AndroidCentral, SlashGear


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Michelle Wilhoit Griffin
As an agent who's an expert in this local area, I bring a wealth of knowledge and expertise about buying and selling real estate here. It's not the same everywhere, so you need someone you can trust for up-to-date information. I am eager to serve you. Here are some of the things I can do for you:
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When it's time to move, you need someone who will advertise your home, show to prospective buyers, negotiate the purchase contract, arrange financing, oversee the inspections, handle all necessary paperwork and supervise the closing. I can take care of everything you need, from start to close.
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Oftentimes buyers don't visualize living in your home the way you do. I can make your home attractive to its ideal audience - which can help you get top dollar. Things like staging the home, making repairs or minor improvements, or even simply painting the walls can be the difference between a home resting on the market and one that's sold fast.
"Michelle spent countless hours helping us to find the perfect home for our family. She beyond professional as well as personable the entire time. She worked tirelessly to make sure our offer was accepted but also, and more importantly, that we were taken care of. She literally worked from sun up to late into the night for us. Since this was only our second home purchase ever she walked us through all of the process, answered all our questions and fought for all our needs. She is the best in her field as we have had other dealings with other realtor in the area as well. You will not only walk away with your dream home but with a new friend as well. "
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To approach this sketchbook, I needed a little release outside of my work and school life. I am a returning student to the Arts. I have always loved to create things. I took a different road of corporate sales and marketing for several years and am now "realigned" with my purpose and passion. This book chronicles the struggles of making difficult changes in my life to put me on the right path.
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T-cell receptor (TCR) plays a key role in immune regulation and polymorphisms of its genes have been found in association with several autoimmune diseases. No data are available for primary biliary cirrhosis, an autoimmune liver disease the natural history of which is highly variable. We studied a TCR constant beta-2 chain polymorphism in 70 patients affected by primary biliary cirrhosis and in 70 healthy controls. The DNA chains of patients and controls were amplified by means of polymerase chain reaction using primers designed around a Bgl II polymorphic restriction site and digested for restriction fragment length polymorphism analysis. We found a slight increase of the heterozygous genotype in patients compared with controls (49 vs 40%), which became higher if only patients with early disease were considered (60 vs 40%). Heterozygous patients had less severe disease as indicated by a lower Mayo score (5.1 +/- 1.2 vs 5.7 +/- 1.2 in non-heterozygous). Our data suggest that TCR constant beta-2 polymorphism does not play a key role in modulating the multifactorial etiopathogenesis of primary biliary cirrhosis.
|T-cell receptor polymorphism in primary biliary cirrhosis
|Settore Scientifico Disciplinare:
|Settore MED/09 - Medicina Interna
Settore BIO/16 - Anatomia Umana
|Data di pubblicazione:
|Article (author)
|Appare nelle tipologie:
|01 - Articolo su periodico
File in questo prodotto:
|annali italiani med.int..pdf
|Publisher's version/PDF
|Open Access Visualizza/Apri


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By Adejumo Kabir
The Association of Campus Journalists, Obafemi Awolowo University, Ile Ife has spread the tentacle of journalism beyond campus as its leadership now creates practicing and employment platform for members.
ACJOAU has designed a platform for all interested members who have passion to be reporting for National Dailies
According to the release made available to our reporter, the opportunity is restricted to those that have registered or renewed their membership with the leadership of ACJOAU.
As at the press time three members have already been shortlisted for Nigerian Cable News based whi opportunities are still available for other national dailies and online such as The Nation, Premium Times, Sahara Reporters, among others.


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That may also be why the FIFA 20 Coins huge sides regularly slip down the table, and we have seen Chelsea and Man City in the relegation zone more than once. The sides should feel a class which would make cracking the top of the table sense a achievement.
We enjoy seeing flit between clubs in career mode to big players since it gives the impression that there is life outside your squad.
Managers, however, are a part of the furniture at their club. They're not hired or fired, and they don't have designs on greener pastures when they're dominating the lower leagues. For those hooked on this year's game, be sure to check out our cheap Fut 20 Coins career style manual.
EA Sports' FIFA 20's big new addition will be Volta Football, a career style blending NBA 2K MyCareer-levels of customization and modification with FIFA Street-style games and tricks.Volta Soccer is part single-player career.
Part multiplayer, with a story mode path, a branch for team play, along with league play between promotion and relegation. For those who wish to play with their sides and celebrities, there's Volta Kick-Off.


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Authors: Huw M. L. Davies Advances in Nitrogen Heterocycles, 1995, 1, 257, JAI Press, ED: Christopher Moody
42. Rhodium(II) catalyzed intramolecular reactions between vinyldiazomethanes and pyrroles. Novel synthesis of fused 7-azabicyclo[4.2.0]octadienes
Authors: Huw M.L. Davies, Julius J. Matasi Tetrahedron Lett., 1994, 35, 5209-5212
33. Enantioselective synthesis of tropanes by reaction of rhodium-stabilized vinylcarbenoids with pyrroles
Authors: Huw M.L. Davies, Nicholas J.S. Huby Tetrahedron Lett., 1992, 33, 6935-6938
19. Novel entry to the tropane system by reaction of rhodium(II) acetate stabilized vinylcarbenoids with pyrroles
Authors: Huw M.L. Davies, Wendy B. Young, H.David Smith Tetrahedron Lett., 1989, 30, 4653-4656


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By Daily Mail Reporter. She may be a new mother, but Kim Kardashian is still finding time for her favourite things - fashion and shopping. The reality TV star, 33, left baby five-month-old North behind - presumably with her nanny - to hit the sales in Miami with her fiance Kanye West on Friday.
Twitter got really bored this weekend. So you know what happens when Twitter gets bored. Out of nowhere someone started talking about sex dolls and Twitter went crazy.
Jade Stanley - who runs Sex Doll Official in the West Midlands - said clients can submit pictures showing what they want their lifesize doll to look like. A sex doll company is flogging plastic partners based on pictures of real women - who often have no idea they are being used. Defiant company owner Jade Stanley told the Daily Star that men also send in pictures of celebrities they want to have sex with. Some send pictures of their partners and Jade said she is not worried if the woman has no idea a sex doll is being crafted in their image.
Okay, first of all, eeeww. But since this story involves a Kardashian, I feel that it is still buzzworthy. The Gist: The curvy reality star, who rose to stardom because of her sex tape with Ray-J, is threatening to sue a company for making a sex doll in her likeness.
Kardashian's photographer accused of misconduct. Taylor Swift announces new son 'The Archer'. Tyra Banks explains feud with Naomi Campbell.
The reality star, who would be a complete nobody if not for her sex tape with Ray J, is trying to erase all memories of her birthday-suit related history. First, she made a stink about Playboy releasing never-before-seen photos from her pictorial. Can't a lingerie-clad model messily eat a mayonnaise-soaked sandwich without Kim Kardashian making it all about herself?!?
Most little kids have a few baby dolls, Barbie dolls, and maybe the odd Disney princess doll. Personally, I always had a thing for my mini Aladdin. Something about that shiny purple vest
By creating an account, you verify that you are at least 13 years of age, and have read and agree to the Comicbook. Mattel makes a lot of Barbie dolls. While most are part of the line of dolls you'd expect to find on the shelves of your local store, according to Kim Kardashian, she has a prototype Barbie made in her own image.
At first glance, Elena Dorfman's photographs could simply be snapshots of everyday, domestic life. There's one key difference, though, that sets her and Jamie Diamond's work in the exhibition " Surrogate. A Love Ideal ," showcased at the Fondazione Prada in Milan through July 22,apart from that of other portrait photographers. Beyond exploring romantic, sexual, and familial love, Diamond and Dorfman also focus on the emotions that can develop between humans and the hyperrealistic, synthetic representations of humans they keep as companions.