text:
One drug that is included in the World Health Organization's list of medicines necessary in the basic health system and which, in 2006, became one of the top selling drugs in the US, is Zofran. Generically known as Ondansetron, Zofran was formulated to prevent and treat nausea and vomiting in patients who have just had surgery, radiation therapy or cancer chemotherapy – the same purpose for which this drug was approved by the US Food and Drug Administration in 1991.
Due to Zofran's efficacy in blocking serotonin, a natural substance inside the body that causes vomiting, its manufacturer, London-based GlaxoSmithKline (GSK), confidently endorsed it for off-label use, specifically for relief from morning sickness, which pregnant women feel during the first trimester of their pregnancy. Aside from this, GSK, as affirmed by the US Department of Justice, also rewarded doctors who prescribed Zofran for morning sickness.
One major issue that involved GSK, Zofran and pregnant women (even prior to Zofran being recommended to treat morning sickness) was the fact that GSK had never tested Zofran on pregnant women, thus the absence of records which will show if the drug is actually safe or harmful to the mother or her unborn child or to both. It seems, however, that the truth behind this issue of being safe or harmful has been known by GSK as early as 1992 due to lawsuit based on birth defect that was filed against it. Despite this knowledge, said manufacturer continued to promote Zofran to treat morning sickness.
There are many different side effects linked to Zofran, including swelling of the body, fainting, difficulty in breathing and/or swallowing, drowsiness, tiredness, dizziness or lightheadedness, constipation, headache, and irregularity in heartbeat. However, none of these side-effects can outweigh the severity of harm which is birth defect (such as cleft palate, cleft lip, or congenital heart defects) which also happens to be the basis of so many lawsuits against GSK.
There are many other things that Zofran users need to understand about this drug, including details about the birth defects linked to it, its history with the FDA, what this product really is, and the legal rights of individuals harmed by it. Information about other defective pharmaceutical products can be found at www.williamskherkher.com/practice-areas/defective-pharmaceuticals/.
While it is the duty of drug and medical supply manufacturers to ensure the effectivity and safety of all their products, they are not given the right to market these products for off-label use. Even if a product is intended as treatment for only one type of health condition, manufacturers still have the legal and moral obligation to test it to clearly determine who can use it safely and who can be harmed by it.
It is alarming, therefore, to know that tens of thousands of patients remain to be harmed either by prescription drugs or medical devices every year. Zofran is just one of the hundreds of drugs found and proven to cause adverse effects; with regard to medical devices, one recently identified harmful product is the power morcellator, a medical device designed to cut large tissues into tiny pieces.
Morcellators were introduced in the 1990s and were intended to aid physicians perform a laparoscopic surgery (such as hysterectomy and myomectomy) that is as painless and bloodless as possible, besides being a fast procedure. Furthermore, unlike in open surgery, the traditional way of performing surgeries, an abdominal incision that was about six to nine inches long is required, while in a laparoscopic surgery, which is a minimally invasive procedure and which makes use of a morcellator, four very tiny incisions, each measuring about 0.5 – 1cm. are all that is required.
Myomectomy is the surgical removal of fibroids from the uterus, while hysterectomy is a procedure wherein the entire uterus, or womb, is removed due to any of the following conditions:
Despite the benefits and advantages provided by morcellators, the US Food and Drug Administration issued a safety communication notice to doctors on April 17, 2014, to discourage them from the further use of the device in surgical procedures, especially in fibroids removal through myomectomy. Morcellators, as studies show, caused the development of leiomyosarcoma, a deadly type of cancer, during the morcellation/cutting of these fibroids. The actual reason behind the development of leiomyosarcoma is the spread of the almost undetectable cancerous tissues called uterine sarcoma, which usually grows with fibroids and which also gets cut into very small pieces (along with the fibroids).
The first company to respond to the FDA's safety communication notice was Ethicon, a unit of Johnson & Johnson and which happens to be the largest manufacturer of power morcellators around the globe. While Ethicon's move to cease the manufacture, promotion and sales of its morcellators may be considered as a really positive move, it may have come late as thousands of women have already been treated with the device.
Definitely, not all of those who have been treated with a morcellator will develop leiomyosarcoma since not all those with fibroids also have uterine sarcoma. For those who have been diagnosed with the deadly cancer, however, consulting with a morcellator lawsuit attorney may be in their best interest. A website with address, www.williamskherkher.com/practice-areas/defective-pharmaceuticals/morcellators/ offers substantial information which someone diagnosed with leiomyosarcoma may just want to know.


text:
Most of us have experienced the loss of very important data, due to a hard drive failure or to a memory card error. When such things occur, we feel sorry for not paying attention to this issue. Generally speaking, data storage solutions are quite reliable, yet accidents happen, so we need to be prepared to minimize their effects by buying a good data recovery software solution.
As most photo cameras of today are digital, it comes without saying that our photos are at risk, should anything occur to the SD card, making it unreadable. If you don't want to lose all your photos and videos from your vacations, you have to make sure you have one of the best data recovery software that works with such cards. Just think about the number of times you were about to format one of your cards before having the chance to download the photos in your computer. This can happen to anyone, so don't imagine you are exempted. Even if you are very careful, it's enough to leave your camera on a table with a curious child around, and your photos could disappear with the simple push of a button. For such situations, as well as for various malfunctions that may occur, you need to powerful and reliable software solution to retrieve lost data.
Card Recovery Pro is an extremely effective and powerful software that can recover your lost photos with only a few clicks. It works on all types of memory cards and it can retrieve the most common types of image and video files. It can even recover raw format files most DSLR and mirrorless cameras use. This makes it one of the essential tools in any photographer's kit.
Card Recovery Pro can recover lost SD card files under a wide array of conditions such as accidental deletes or formatting, improper operation, physical damage and various other errors. If, for instance, you have mistakenly used your card in the wrong camera or if you have powered off the device during the data writing process, you may need Card Recovery Pro to get your files back. This software has the great advantage of working with virtually any type of memory card known today. It works on SD cards, micro SD, SDHC, mini SD, MMC, CF cards, Memory Stick Pro, Smart Media, Flash Cards and xD picture cards. The program supports devices from the biggest manufacturers in the world. Whatever your digital camera brand, you can be sure your photos are going to be safe with this recovery software.
Last but not least, this program is compatible with micro SD cards used in Android phones. Thanks to its SmartScan technology, Card Recovery can complete extremely difficult recovery tasks other software can't handle. This is one of the reasons why this solution is probably the best one you can find. Besides, its step-by-step wizard interface type makes it extremely easy to use, this being one more reason to choose it over other similar programs.

subset: commoncrawl


text:
Wednesday, May 30, 2012
[Light Reading] Rumors: Tekelec Seeking a Buyer
Ray Le Maistre (pictured) reports to Light Reading that "the new private equity owners of Tekelec Inc. are believed to be seeking a buyer for its Broadband Network Solutions business, which includes the company's policy control, diameter signaling router and subscriber data management (SDM) assets".
".. Tekelec was acquired for $780 million in January by a consortium of investors .. Now, according to a number of industry sources, the owners are looking to cash in on the growth part of the business and manage the older side of the company that should generate cash-flow for a few years yet .. industry sources, though, say the Broadband Network Solutions unit has been offered to a number of companies, including the IP router vendors and IMS (IP Multimedia Subsystem) players .. One industry executive ventured a potential sale tag of $500 million".
The Broadband Network Solutions unit includes the Policy Management product line [ex Camiant], Diameter Singling Router (see "Tekelec: 10 New Diameter Router Customers; Total of 19" - here) and SDM products.
"Tekelec is saying nothing about the speculation".
See "Tekelec Back in M&A Mode" - here.
Posted by Azi Ronen at 6:04 AM
Labels: Lightreading, Tekelec
Subscribe to: Post Comments (Atom)


text:
Chewing Gum
X_Butyl® RB 101-3 is a specialty product manufactured for the chewing gum industry. Our company applies the most stringent quality controls, consistent with food regulations and standards implemented worldwide. Because of its low permeability, flavor is retained longer than with natural rubber-based products and the transmission of air and water are minimized. Its low-temperature flexibility prevents it from becoming brittle and shattering, even in heavily-filled compounds.
X_Butyl® outstanding stability and resistance to ageing prevents hardening during shelf storage and thus helps to retain the soft texture required for stick gums. It also serves as a hydrophobic plasticizer, providing softness and smoothness to enhance chewing.


text:
Is SCO guilty of entrapment and harassment?
a) Entrapment is a concept only in criminal law and does not apply here. The question is whether they are misrepresenting that the use of the download is free. I don't have any of the details so I can't really comment.
b) I am sorry that you have been so personally affected by all of this; you are not alone, to be sure. I am unaware of any legally recognized claim for harrassment under these circumstances. If SCO knew that you were a developer/designer, that its actions were interfering with your business relationships and that SCO intended to adversely affect those relationships, you might have a claim for intentional interference with economic relations. Such a claim seems like a stretch given what appears in your e-mail.
Dig Deeper on Linux servers
Have a question for an expert?
Please add a title for your question
Get answers from a TechTarget expert on whatever's puzzling you.
Meet all of our Data Center experts
View all Data Center questions and answers


text:
Many people have a lot of myths about what being an entrepreneur is and how it will shape/affect their life that are simply not true. Great Entrepreneurs In South Africa in Tip and these are the seven biggest myths that I continuously hear.
1. Being an Entrepreneur is too risky for me.
Starting your own business in these days is not too much more risky than trying for any other corporate job. At a corporate job you can be laid off at any time, Young Successful Entrepreneurs In Africa have benefits cut with no reason, and work long overtime without being compensated for that. If you are student as well, the risk can't be that bad. It's not like you have a mortgage or family to support if it fails.
2. I am too young to start my own company
Being young is not a negative, in fact in most cases it's a positive! When your young you have the passion energy and enthusiasm that is needed to work 14 hour days day in and day out for a company you believe in. Most older people with more experience just don't want to do that any more.
3. I have no experience
Again, Great Entrepreneurs In South Africa this can work towards your advantage. Your lack of experience means that you are looking at everything with a fresh set of eyes. You wont get stuck in the "we have always done it that way" kind of thinking that can stop other entrepreneurs. Running your own company will also build much more valuable experiences than a job flipping burgers will at your age.
4. It is not the right time for me to launch a business.
As a student you have a schedule that is completely flexible and large blocks of time between classes and on breaks to start a business. Campuses have tons of resources you can harness as well, Two Successful Enterpreneurs In South Africa so there really has never been a better time than now.
5. If I am running a business my grades will fall.
Running a business takes organization and discipline. If you are organized and disciplined in one area of your life it will probably pass over to the other areas of your life as well. Many student entrepreneurs I know actually report their grades increasing once they started a business.
6. Student businesses are just small rinky-dink operations
Some student business that started as just rinky-dink operations were Dell, Google, and Microsoft. You have probably heard of those companies right? That is because they were great ideas and hard work created products that had potential to expand from their small beginnings. Your business can too!
7. I don't have any money! I can't start a company
Everyone seems to think only millionaires start companies. This is simply not true. Most companies are started with the founders savings and no investment capital. Start with what you can and work hard. Things will come together if you want them to come together. You will be amazed at what you can do!
Great Entrepreneurs In South Africa in Tip?
Successful Entrepreneurs Are...
1. Visionaries
They see beyond obstacles. They focus on possibilities rather than
dwelling on limitations.
We hear many stories of men and women who have created great
enterprises from ideas others had rejected or said will never work. We are
inspired the most by stories of those who succeeded against all odds. As
an entrepreneur, you have the need to create, to start something that never
was or to improve upon an exciting product or concept. To bring forth
something new does not come without challenges.
Choose not to dwell on what you don't have (lack of money, time, support
or other resources). Make a choice to focus on what needs to be done to
manifest your idea and then make it happen! No more excuses! Stop
blaming others, your circumstances or yourself for why things don't turn
out as you thought they would. When we choose to focus on abundance
rather than lack, we harness the power to create and attract what we need
to achieve success. Those with sight see what is, but those with vision see
what can be. What are the possibilities in your life, what are the
possibilities for your business?
2. Strategists
They plan well, and execute effectively.
Sun Tzu, in his book, "The Art of War" he wrote, "the art of war is a
matter of life and death, a road to either safety or to ruin. The art of war is
governed by five critical factors. These are the way, the weather, the
terrain, the leadership and the discipline." Without a solid business
strategy, you become, by default, reactive rather than proactive. Reactive
businesses cannot grow into sustainable and competitive enterprises
because there is no roadmap to do so. Sun Tzu's five critical factors apply to contemporary business strategy as much as they do to historical military operations. To drive your business
using the art of strategy, it is essential to establish or clarify the overall
vision and goals of the organization (the way); understand the operating
environment facing the business (the terrain); develop objectives and
specific strategies for the organization to address (the weather); ensure
strong management to guide and motivate staff and to implement the
strategies in a timely manner (the leadership); and develop a robust
organizational structure, effective supply chain management and ensure
that performance is monitored against the stated objectives (the
Entrepreneurs often have great ideas, but in a zest to make it a reality, fail
to plan properly. This failure to plan can sink even the best of ideas.
Address the 5 critical factors as soon as possible by creating your strategic
plan if you haven't already done so. If you have already created your
strategic plan, it doesn't hurt to give it the once over to ensure all the
critical factors have been addressed.
3. Problem - Solvers
They see a problem as an opportunity for growth and strategically seek
Are you solutions-oriented? How do you react when faced with a business
problem? Problems are just opportunities for growth and development in
disguise. Problems test you; they challenge you to change the way that
you think. There are thousands, if not millions of great inventions born
from perceived problems or accidents.
George de Mestral, a Swiss engineer, returned from a walk one day in
1948 and found some cockleburs clinging to his cloth jacket. When de
Mestral loosened them, he examined one under his microscope. The
cocklebur is a maze of thin strands with burrs (or hooks) on the ends that
cling to fabrics or animal fur. By the accident of the cockleburs sticking to
his jacket, George de Mestral recognized the potential for a practical new
fastener. It took eight years to experiment, develop, and perfect the
invention, which consists of two strips of nylon fabric. VELCRO, the
name de Mestral gave his product, is the brand most people in the United
States know. It is strong, easily separated, lightweight, durable, and
washable, comes in a variety of colors, and won't jam.2
Learn from George. Begin to look forward to your next problem; if you
look carefully enough, it may be a great blessing in disguise. What
creative and/or strategic solutions can you come up with and implement?
4. Risk -Takers
They are not afraid to challenge the status quo nor, are they afraid to take
the road less traveled.
The great people of this world are not the ones who did what had always
been done, they are the ones who stood up and said, "how I can do this
differently"? Great people are bold, they dare to dream, and they are
courageous in their endeavors. Little people are timid; they are scared to
dream and to avoid disappointment they refrain from great endeavors. It is
better to try and risk not reaching the desired end, than never to try and
never know what could have been. The level of success you may desire to
achieve may not have been paved by any before you. You may not be only
taking the road less traveled, but a road never traveled.
In order to succeed, sometimes you have to break the cycle of what
everyone says is fact and believe in what you know to be true. Christopher
Columbus knew the truth that the world was round even when the facts of
his age said it was flat. What would have happened if Columbus accepted
the norm and didn't challenge the status quo? This is not to say do not
heed good advice, as a matter of fact it is wise to seek good counsel. But
there are times when we have to make choices, small ones and big ones
alike that are contrary to popular opinion. These are the times when you
must separate the facts from the truth. The fact may be that you have a
great business idea, but no money to get it off the ground; however, the
truth is that you live surrounded by an abundance of all you need to get
your business off the ground but you have to learn how to tap into it. This
is where you must be creative, do something that you have never done
before; boldly seek partnerships, mentors and coaches to help you. Are
you afraid to take bold risks? Will you be content with playing it safe and
spending the rest of your life wondering what could have been?
5. Servant-Leaders
They realize serving precedes leading.
A servant leader does not just focus on the bottom line but focuses on how
she can be of service to others. A servant leadership model is an inverted
pyramid in which the president of an organization is at the lowest point of
the triangle and the customer is at the broadest edge as opposed to your
traditional leader on top of the organization model.
Robert Greenleaf is credited with the term servant leader. In his book,
Servant Leadership, Greenleaf noticed that the most successful
managers led in a very different way - they led through service rather than
through positional authority.
Resolve today that your leadership, as an entrepreneur, is not purely self-
satisifying and profit motivating. Leadership is not about control and
manipulation, as it is only in service that one becomes great. Resolve to
be of service to your employees, shareholders, clients, suppliers and all
those you come in contact with.
If you are interested in learning more about servant leadership many
universities even community programs offer courses on the subject.
It is a worthwhile investment.
6. Survivors
They don't quit. Instead, they fail forward to success.
Your first business venture may not work out as planned. Maybe neither
will your second venture or third. It is important to know that because
things don't always turn out as planned, it does not mean you are a failure.
Your business may have failed, but you have not! Smart entrepreneurs
learn from what didn't work instead of throwing in the towel all together.
Robert Kiyosaki actually said in one of his books that, unlike employees
entrepreneurs get paid to fail. What a strange statement, but it is true!
Entrepreneurs learn something valuable every time things go awry. As
humans we are programmed to learn by our mistakes more than our
successes. Did you know how to ride a bike the first time you got on one?
Could you use chopsticks as effortlessly as you can now? No! You learned
from your mistakes and eventually, you got it right.
By giving up, you throw away the opportunity to ever succeed. Every
time you stumble or fall in your entrepreneurial undertakings, rejoice, as
you are one step closer to success! You may have to change what you are
doing slightly or dramatically but whatever you do, don't quit!
1 [http://www.grantthornton.ca/mgt_papers/MIP_template.asp?MIPID=29]
2 http://www.ideafinder.com/history/inventions/story015.htm
Entrepreneurs - Clear a Path For Your Spouse If You Want to Be on the Same Page
Some Hot Business Opportunities for Entrepreneurs
These days, a lot of trends in the business arena have surfaced. In a year, several business opportunities for entrepreneurs rank as the hottest. So as a budding entrepreneur, what field would you like to get into? It is believed by many that in opening a business, it must be something within the scope of your own expertise.
You need to have an initial knowledge about what opportunity you are getting into. In managing any type of business, it is a must that you exert a personal effort on it. But then as the times are concerned, it goes to point out that the business of your choice must be something which is within the trends and that which is appreciated by the consumers. Or else, you are opening yourself into some great possibilities of losing in business.
For a guide, here are among the hottest trends of business opportunities for entrepreneurs in the year 2006:
Communications Coach or Writing Instructor. Most American businesses involve the flow of communications. After all, how can a business transaction transpire if there is no communication that exists within the concerned parties? Most office personnel in America lack one skill—and that is the power to communicate effectively.
In all levels of business, the staff members are asked to communicate orally, verbally, or technologically. But then most of them fail to do well in the task. They cannot even generate sensible sentences for that matter. Unfortunately though, a lot of English classes held in high school and college levels tend to overlook this matter so the graduates are not molded for these kinds of situations. One of the hottest business opportunities for entrepreneurs this year is to put up groups that would coach people in the entrepreneurial level in terms of communication. Many American companies seek the services of communications coaches and writing instructors.
Blogging. In a technologically advanced world, most information, ideas, and transactions are already done via the net. Blogging is one of the hottest and rising business opportunities this year. Whether the phase is internal or external, the blog must be well written so that it will be highly effective. Most companies involve blogging as part of their marketing strategies and if the blog is more or less poorly conceived, you know exactly what it will reflect for the company. The corporations that employ blogging as part of their businesses should provide ample training background in writing skills to their staff members.
Security and IT Privacy Consultant. For companies that mainly run technological-based industries, what they need are people who are IT competent and who knows how to troubleshoot technological problems. Since they deal much with information, they also need sufficient security. That is why masters in these matters are very much in-demand. As an entrepreneur, you can put up a business that relates to this need.
Some Construction-Related Operations. The country cannot rid of constructions of all types since it is moving towards global competitiveness. In the midst of all these constructions are great opportunities for entrepreneurs that are concerned with the plumbing, electric, carpentry, drywalling, and general contracting services.
Home Caregiving. In America per se, the aged individuals are always put in Home for the Aged institutions as their children are busy to care for them. It has been a custom to hire home caregivers for them. In the rate of employment, there are several individuals who go for caregiving since it is a highly paid job. If you may be interested, you can put up a home caregiving agency and earn much because of the high demand for such services.
Medical Technician or Home Healthcare Nurse. This business opportunity is likely related to the discussion above.
Virtual Assistants. The demand for virtual assistance is all the more increasing. People who would like to have online secretaries who can take charge of anything which they need pay much just so they can avail of the service. As an entrepreneur it will be beneficial on your part to come up with a set of staff members to work as virtual assistants.
Ebay Trading Assistants. People certainly love to shop on ebay especially with all those auctions. Being a seller in the website can invite lots of money for you.
Mobile Phone Applications. People cannot be detached from their mobile phones these days. So the demand for more advanced and upgraded phones increase each day. Outlets for mobile phones sales and repairs all the more prove to be successful this year.
There are more and more business opportunities that may knock on the doors of budding entrepreneurs. If you know how to handle a business, you will likely succeed.


text:
GF Piping Systems presents at ISH 2019 in Frankfurt / Main everything for safe, standard-compliant and economical drinking water installation and efficient cooling in residential and commercial buildings. Visit us from March 11 to 15, 2019, in Hall 4.0, booth F57 and in Hall 8, both A50.
Learn more: All information about the ISH
GF Piping Systems is the preferred partner of owners and operators of residential and commercial buildings. Our solutions support reliable, effective and sustainable construction and management. They also help lower construction and maintenance costs and accomplish standards for energy-efficient and ecological construction and building management. The services of GF Piping Systems support customers in every phase of the project.


text:
全球发货 !
SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). 再加上,我们可以发 和 和数多这个蛋白质的别的产品。
Showing 10 out of 68 products:
Human Polyclonal SLC5A8 Primary Antibody for WB - ABIN2781721
Zhang, Bao, Yang, Wu, Yu, Huang, Sun, Zheng, Li: Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells. in The international journal of biochemistry & cell biology 2010
Show all 3 Pubmed References
Human Polyclonal SLC5A8 Primary Antibody for WB - ABIN4892821
Nedjadi, Moran, Al-Rammahi, Shirazi-Beechey: Characterization of butyrate transport across the luminal membranes of equine large intestine. in Experimental physiology 2014
Show all 2 Pubmed References
Slc5a8 is an obligatory link between dietary fibre and mucosal immune system via the bacterial metabolite butyrate and that this transporter is a conditional tumour suppressor in colon linked to dietary fibre content.
Data indicate oncogenic HRAS (HRAS(G12V)) as a potent mediator of SLC5A8 silencing in human nontransformed normal mammary epithelial cell lines and in mouse mammary tumors through DNMT1.
Efficacy of LP or their secreted soluble factors to stimulate SMCT1 expression and function and to counteract the inhibitory effects of TNF-alpha on butyrate absorption could have potential therapeutic value.
butyrate and propionate block the generation of dendritic cells from bone marrow stem cells, since Slc5a8 transports butyrate and propionate into cells, and these two bacterial metabolites inhibit histone deacetylases
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
In conventional mice with normal bacterial colonization of the intestinal tract, GPR109A and SLC5A8 are expressed on the apical membrane of epithelial cells lining the ileum and colon.
CDX1 and CDX2 bind the promoter region of SLC5A8 and up-regulate its expression in cultured cells and in colonic epithelium.
slc5a8 is expressed abundantly in the kidney and plays a role in the active reabsorption of lactate
SMCT functions not only as a Na+-coupled transporter for short-chain fatty acids and lactate but also as a Na+-coupled transporter for the water-soluble vitamin nicotinic acid.
The shared epigenetic inactivation of mSLC5A8 in mouse gliomas indicates an additional degree of commonality in the origin and/or pathway to tumorigenesis between primary human tumors and these mouse models of gliomas.
Data describe the cellular localization of Slc5a8 in the murine gastrointestinal tract and kidney by in situ hybridization and immunohistochemistry.
slc5a8 and slc5a12 in kidney in c/ebpdelta-/- mice have a role in the renal handling of lactate and urate
SMCT1(SLC5A8) expression in intestinal tract was examined by immunofluorescence microscopy.
These data provide the first evidence for the expression of SMCT1 and SMCT2 in the retina and for the cell-type specific distribution of these transporters within the retina.
low-affinity transporter SMCT2 initiates lactate absorption in the early parts of the proximal tubule followed by the participation of the high-affinity transporter SMCT1 in the latter parts of the proximal tubule.
Cellular expression of a sodium-dependent monocarboxylate transporter (Slc5a8) and the MCT1/2 in the mouse kidney.
SLC5A8 expression is repressed in human cervical cancer (CC) tumors and cell lines through epigenetic silencing.
Results indicate that the SMCT1-PDZK1 interaction thus plays an important role in both lactate handling as well as urate reabsorption in the human kidney.
Pendrin residues which are mutated in Pendred's syndrome are identical to those in the aligned position of sodium/iodide symporter (NIS) and apical iodide transporter (AIT).
The present work reveals much lower iodide affinity in the pocket of human SMCT1 analogous to the putative iodide-binding pocket of human NIS.
Human SMCT1 is regulated by insulin and SGK1.
Data suggest positive correlation between BMI (body mass index)/waist circumference in morbidly obese or obese subjects and jejunal mucosa mRNA abundance of SMCT1; BMI was not significantly correlated with mRNA abundance for glucose transporters SGLT1 and GLUT2 or the low-affinity short-chain fatty acid/monocarboxylate transporter SMCT2.
Underexpression of SLC5A8 is associated with hepatocellular carcinoma.
Data suggest that SLC5A8, SLC5A5 (sodium-iodide symporter), and SLC26A4 (pendrin), the 3 known iodide transporters, are important in breast tissue metabolism in lactation and in breast neoplasms. [REVIEW]
Gene silencing of SLC5A8 by hypermethylation was associated with poor prognosis in cases of node-negative stage I and II lung adenocarcinoma.
These results suggest that DNA methylation in the SLC5A8 promoter region may suppress the expression of SLC5A8 in lung tumor.
SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function
SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.
SLC5A8 has a role in prostate cancer risk and aggressiveness
SLC5A8 is highly methylated in African American colon adenomas
Results verify IRX1, EBF3, SLC5A8, SEPT9, and FUSSEL18 as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1, EBF3, SLC5A8, and SEPT9.
results elucidate the mechanism underlying the regulation of SLC5A8 gene transcription and also define a novel regulatory sequence that may be used to increase expression of the SLC5A8 gene in cancer gene therapy
SMCT1 possesses a anionic leak current that becomes significant whenever external Na(+) concentration is reduced
SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002
apical iodide transporter , putative
, electrogenic sodium monocarboxylate cotransporter
, sodium-coupled monocarboxylate transporter 1
, solute carrier family 5 member 8
, sodium-dependent monocarboxylate cotransporter
, apical iodide transporter
, sodium iodide-related cotransporter
, solute carrier family 5 (iodide transporter), member 8


text:
Click here for Latest Ankara Styles >> Read More
Banky W, Miss Kedike Feature Nollywood Stars In "All I Want Is You''
— Feb 17, 2016 3:37 pm |
Nigerian music artists Banky W and Miss Kedike have released a new video titled "All I want is you".
Olubankole Wellington referred as Banky W and Chidinma Ekile also known as Miss kekide said that the music is a modern day Nigerian Love story.
The artist played the characters of falling for each other, despite the disapproval of her parents.
In a statement, Banky W underscored the need to fall for the right person adding that all a man need is a good wife material that can look after a home.
"It shows how far one can go to fight for the chance to love and believing that love is supreme.
In the video, Nollywood icon, Zack Orji and Onyeka Onwenu played the role of a respectable parent who didn't want their daughter to marry due to tribalism.
Banky W said the video was shot in Lagos and was written, produced and directed by him for EME / TILT Productions.
Miss Kedike became known after she won the season three of the MTN Project Fame West Africa.
Aside from being an MTN Ambassador, she has also featured in more than 10 songs and she won the 2013 Nigeria Music Video Awards (NMVA).
She has also won the best Female West African Act in the song "Kekide" in 2012.
Aside being a musician, Banky W, established the Empire Mates Entertainment (EME) record label as a medium to get his music to his fan.
He has featured in so many nominations and awards where the bagged the best R&B singer in the male category, Best Music Video in the 2010 people Entertainment Awards. (NAN)
Click here for Latest Ankars Styles READ MORE
Click here for Latest Aso Ebi Styles
. .
<. class="clearfix" .="0.0920245398773">
« . Article
Popular Nigerian Comedian, 'I Go Dye' Goes On World Tour
Click here for Latest Ankara Styles >> Read More
Skiibo - Free Dating & Chat App DOWNLOAD SKIIBO APP


text:
Money Observer has lined up 22 major investment platforms to help you find the best online broker, taking into account charges and the range of investments on offer.
Money Observer has lined up 22 major investment platforms to help you find the best online broker, taking into account charges and the range of investments on offer, with the help of platform consultancy The Lang Cat. With so much confusion about the true cost of investing we hope this will help you make an informed choice when deciding which investment platform to invest with.
We have ranked the platforms in order of total cost of running a £100,000 portfolio assuming 10 trades per year. For fees charged on individual savings accounts and Sipp portfolios, see our separate articles here.
Please bear in mind information was correct at the time of writing. When we become aware of changes we will update the article but we can't guarantee that all information will be correct. If you spot an error please contact us with a description and a link to the correct information.
If you wish to view the whole of this special report in one place, you can do so in the July edition of Money Observer. Click here to subscribe and receive three copies worth £14.95 for just £1.
£100,000 Portfolio charge - £63
Dealing: shares and funds £12.50 per online trade. Telephone trades are £25 per trade. There are no monthly or annual administration charges on the online share dealing account. Regular investments are charged at £2 per trade.
Accounts: a Stocks and Shares Isa is £12.50 per year. Quarterly Sipp charge £22.50 up to £50,000, doubling to £45 if you go over that amount.
Platform fees: no administration fee.
Range of assets: UK and international shares, funds, ETFs, investment trusts, bonds and gilts.
Tools and features: range of research tools, company analysis tool, news and education sections, information and stat channel for investment companies, detailed analysis of funds by fund manager and sector, fund screener charges and performance tool.
Ready-made portfolios: no.
£100,000 Portfolio charge - £80
Dealing: Interactive Investor charge £20 per quarter, including two free trades.
Accounts: for a Sipp account there is a flat fee of £96 plus VAT per year.
Platform fees: real-time trades (all assets) are £10 each; frequent traders get a rate of £5 and UK shares can be bought for a regular investment rate of £1.50.
Range of assets: whole of market coverage, including UK and international shares, ETFs, investment trusts, VCTs, funds, bonds, gilts, warrants, futures, options, forex, CFDs, spread-betting and retail bonds.
Tools and features: fund and share research; selection filters; virtual portfolio for tracking and monitoring potential investments
Ready-made portfolios: a range of 12 model portfolios catering for different risk profiles and time horizons. These are available at £10 per portfolio.
£100,000 Portfolio charge - £140
Dealing: reduce over time - £12.50 a trade (online) for first five years, reducing over time to £9.38 for 20 years and longer.
Accounts: Isa at £7.50 a month, Sipp 'savings' at £15 plus VAT a month, Sipp 'income' at £21.25 plus VAT a month, Junior Isa at £3.33 a month, Child Sipp at £6.65 plus VAT a month
Platform fees: an individual dealing account is £7.50 a month.
Range of assets: unit trusts, Oeics, ETFs, ETCs, UK equities, Aim shares, share certificates, UK gilts and corporate bonds, investment trusts.
Tools and features: online trading dividend re-investment, investment research, online valuations, transaction history, statement and valuations and online customer magazine.
Ready-made portfolios: no.
£100,000 Portfolio charge - £180
Dealing: Investment Centre transactions (buy, sell or switch) – £Nil (online) or £20 (paper instruction). External investments (buy, sell or switch) - £20 (online) or £50 (paper instruction).
Accounts: annual Sipp fee £195, waived if more than £195,000 in core investments.
Platform fees: 0.18 per cent on up to £500,000; 0.15 per cent on £500,000-£1 million; 0.05 per cent on £1 million plus.
Range of assets: UK shares including Aim, overseas shares, investment trusts, UK Reits, ETFs, government securities, loan stocks, derivatives, unit-linked funds, commercial property, collective investments, fixed-term deposits, second-hand or traded endowment policies, structured products, income bonds, National Savings and Investment products, unquoted private shares, investment-grade gold bullion.
Tools and features: illustrations, trade tracking, reports, including daily valuations and transaction history among others; literature library; access to the Selftrade trader terminal for equity trades; market research and company data; performance reporting; asset allocations; fund Research for iSipp; cash alerting; investment managers money transfers and cross-client analysis.
Ready-made portfolios: yes, investment portfolios for various risk profiles and investment objectives.
£100,000 Portfolio charge - £184
Dealing: trades (all assets) 1 per cent. Frequent trader option (£20 plus VAT per quarter) costs £7.50 per trade flat fee.
Accounts: Sipp £12 plus VAT a month (£178.20 per year).
Platform fees: a monthly admin fee of £1.50 + VAT per month; regular investing is charged at 0.5 per cent.
Range of assets: shares, funds, investment trusts, bonds, gilts, ETPs, complex investments such as securitised derivatives.
Tools and features: share and fund pickers, 120 selected 'platinum' funds, fund comparison tool, investment guides, how-to videos, a view on every FTSE 100 share, buy list of recommended stocks, range of articles and guidance for new and experienced investors.
Ready-made portfolios: yes, for cautious, positive or adventurous investors, all funds of funds, no dealing commission.
£100,000 Portfolio charge - £220
Dealing: equity and fund trades £5 each. For international trades there's a 1.5 per cent foreign currency charge.
Accounts: one-off £200 charge for first account.
Platform fees: no annual or monthly charges. No inactivity charges.
Range of assets: UK stocks, ETFs, unit trusts, bonds, also shares available on some international exchanges.
Tools and features: research centre, including stock exchange data and analysis of funds and stocks; company information.
Ready-made portfolios: no.
£100,000 Portfolio charge - £100 if all in shares, £250 if all in funds
Dealing: fund transaction fee is £1.50; regular investment trading fee is £1.50; equity trading fee £9.95.
Accounts: No account charge.
Platform fees: share charges (including investment trusts, ETFs, gilts and bonds) are 0.25 per cent (maximum £25 per quarter for a SIPP, £7.50 per quarter for an ISA or dealing account, £5 per quarter for a Junior Isa). Fund charges (including unit trusts, OEICs and structured products): first £0-£250,000 charged at 0.25 per cent, between £250,000 and £1 million is 0.1 per cent, £1 million-£2 million is 0.05 per cent and over £2 million has no charge.
Range of assets: funds including clean funds, UK and Irish shares, international shares from 21 markets, ETFs, ETCs, investment trusts, government bonds, corporate bonds, PIBs and covered warrants.
Tools and features: research centre powered by Morningstar and covering shares, funds, ETFs and investment trusts, sector tools and quick-rank tools, an 'x-ray' portfolio tool, news, index information, and Sipp illustration tool.
Ready-made portfolios: yes, three global tracker fund portfolios for a cautious, balanced and adventorous investor.
£100,000 Portfolio charge - £240
Dealing: fund transactions free, equities £2.50 per trade with a loyalty bonus for larger sums - £1.50 rebate for £250,000-plus, £2 rebate for £500,000 plus. Loyalty bonus capped at £4,000 per year.
Accounts: no additional fee for Isa or Sipp.
Platform fees: annual platform charge 0.24 per cent, collected quarterly, with minimum £30 per quarter.
Range of assets: shares, investment trusts and funds.
Tools and features: access to Sharecast market and shares news and tips, charting tools, portfolio x-ray, fund comparison and research.
Ready-made portfolios: no.
£100,000 Portfolio charge - £240
Dealing: fund/share transactions £10 per trade, £6 for frequent traders.
Accounts: annual Sipp administration charge of £96.
Platform fees: annual service charge 0.25 per cent (capped at £200 a year).
Range of assets: clean share class funds, unit trusts, Oeics, all London investment trusts, ETFs, VCTs, bond funds and IPOs.
Tools and features: access to all FE research, data, editorial features, extensive selection of tools, demonstration portfolios.
Ready-made portfolios: yes, three portfolios - accumulator, consolidator and income generator - for the three broad stages of investment, as well as four portfolios for more specific situations, including regular Isa saving, 'retirement booster', school fee planner and 'mortgage buster'.
£100,000 Portfolio charge - £250
Dealing: investment trusts and ETPs dealing fee of 0.1 per cent.
Accounts: no account fees for Isa or Sipp but one-off £35 initial fee for personal pensions.
Platform fees: ongoing platform charge of 0.25 per cent for Isa and investment accounts (0.2 per cent on the entire balance for accounts worth over £500,000) or 0.3 per cent for Sipp accounts (0.25 per cent on the entire balance for accounts worth over £500,000); plus fund manager charges of 0.06 to 1.96 per cent.
Range of assets: full range available on FundsNetwork platform: around 3,000 funds, plus 80 exchange traded products and 90 investment trusts.
Tools and features: 'almost identical' to those available to those on the Fidelity website, including portfolio x-ray analysis and Chart & Compare.
Ready-made portfolios: yes, 12 in total, maintained by an external company and reviewed and updated monthly.
£100,000 Portfolio charge - £250
Dealing: fund transactions free, equities £10 per trade.
Accounts: Sipp charge £100 plus VAT per year.
Platform fees: shares 0.25 per cent, capped between £20 and £150, waived if minimum six chargeable trades made in a six-month period; funds 0.25 per cent up to £500,000 across platform, then dropping to 0.15 per cent on funds in excess of £500,000 across all accounts, reducing to 0.05 per cent on fund holdings in excess of £2 million.
Range of assets: clean price funds, UK shares, ETFs, investment trusts, gilts, corporate bonds.
Tools and features: list of preferred investments, including funds and investment trusts and passive investments.
Ready-made portfolios: yes, five example portfolios for different types of investor.
£100,000 Portfolio charge - £250
Dealing: transaction charge for equities, investment trusts, ETFs gilts, £8.95 per trade.
Accounts: no Isa or Sipp fees
Platform fees: annual charge for equities, investment trusts and ETFs 0.25 per cent.
Range of assets: UK equities, investment trusts, UK gilts, fixed-term deposits, unit trusts and Oeics.
Tools and features: fund research notes, watchlist, portfolio x-ray and monitoring of off-platform assets, Close 50 funds list.
Ready-made portfolios: yes, the Close Discretionary Managed funds.
£100,000 Portfolio charge - £300
Dealing: fund transactions free. Equities, ETFs, bonds, trusts £12.50 per trade; frequent traders £5.95 or £8.95.
Accounts: Isas £0 if balance £5,100 plus at end May; otherwise £30 + VAT per year. Sipps 0.25 per cent per half year, max £100 + VAT.
Platform fees: funds platform charge tiered 0.3 to 0.2 per cent with £1,500 annual cap.
Range of assets: UK equities, investment trusts, unit trusts and ETFs, Reits, 17 international markets, spread betting, CFDs, forex trading, futures, covered warrants.
Tools and features: portfolio x-ray, virtual portfolio, fund and ETF selectors, 60 recommended funds list, daily trading ideas and technical insights.
Ready-made portfolios: no.
£100,000 Portfolio charge - £310
Dealing: fund transactions free. Equities, investment trusts and ETFs £9.50 per trade.
Accounts: Sipp fee £100 plus VAT per year.
Platform charge: 0.35 per cent on up to £50,000; 0.25 per cent £50,000-£1 million; 0.1 per cent above.
Range of assets: UK Oeics and unit trusts, Ucits IV-compliant overseas Oeics and Sicavs, UK investment trusts, ETFs, LSE main market and Aim equities.
Tools and features: research centre for tracking and comparing performance, investor guides, multi-asset investment ideas for first-time investors, top 20 investment list, and a 'Make it Easy' service to help investors hit their goals potentially through target date funds.
Ready-made portfolios: yes, target date funds available through the 'Make it Easy' service.
£100,000 Portfolio charge - £350
Dealing: no trading fees.
Accounts: no account admin fee for funds. No Sipp account available.
Platform charge: 0.35 per cent for first £250,000 for Isa or trading account, falling to 0.20 per cent for anything further.
Range of assets: more than 1,250 funds.
Tools and features: risk profiler, Isa value forecaster, top 100 'favourite funds'.
Ready-made portfolios: yes, three quick start portfolios (bond-led, mixed asset, equity-led). Also five all-in-one multi-asset funds managed by Architas.
£100,000 Portfolio charge - £350
Dealing: equities £11.95 a trade, falling to £8.95 for 10 or more and £5.95 for 20 or more.
Accounts: Sipp charge £155 plus VAT per year; Isa account charge £30 plus VAT per year, if invested in anything other than funds.
Platform fee: 0.35 per cent (minimum £35, maximum £1,750).
Range of assets: funds, equities, ETPs, investment trusts, covered warrants, gilts, structured products, IPOs and corporate bonds.
Tools and features: research centre, monthly publication, virtual portfolio tool, educational content via Smart Investor web portal, price improver system to compare trading prices available to clients.
Ready-made portfolios: no.
£100,000 Portfolio charge - £350
Dealing: no longer providing a share dealing service.
Accounts: no account fees for Isa or Sipp.
Platform fees: 0.35 per cent, up to £250,000. The fee drops to 0.2 per cent on the whole portfolio for investors with more than £250,000. No charges on assets held above £1 million.
Range of assets: funds, trusts and ETFs.
Tools and features: guidance service, Investment Explorer iPad app, Nisa and junior Isa calculator, price comparisons, a 'select 50 list' of favourite funds, investment guides, 'people like me' tool with information about choices made by investors in similar circumstances, analysis of funds by fund manager and sector. Investment video hub.
Ready-made portfolios: no, but there is a Fidelity PathFinder tool, which suggests in-house Fidelity funds for various risk levels.
£100,000 Portfolio charge - £350
Dealing: can only buy funds.
Accounts: no account fees for Isa.
Platform fees: flat percentage fee of 0.35 per cent.
Range of assets: around 1,500 funds.
Tools and features: savings plan tool, fund selector and filter, rated funds, range of guides and videos.
Ready-made portfolios: yes, four pre-selected portfolios for different risk profiles.
£100,000 Portfolio charge - £350
Dealing: £7.50 per trade. Accounts Isa and Sipps – the latter carries an annual administration fee of £132.
Platform fee: tiered fees of 0.4 per cent for the first £50,000, dropping down to 0.3 per cent for the next £50,001 to £100,000, 0.2 per cent for the next £100,001 to £250,000 and 0.15 per cent for the next £250,001 plus. Fund transactions free. Sliding annual fee ranging from 0.40 down to 0.15 per cent. Previously levied platform fee paid to Cofunds, but this has been removed since the launch of Willis Owen's own platform.
Range of assets: funds, ETFs, investment trusts and shares.
Tools and features: Your Space online investment portfolio, including research and valuations, Play Space virtual portfolio, free online tool to access all investments, including pensions, bonds, shares, Sipps, or Isas.
Ready-made portfolios: no.
20 tILNEY BESTINVEST
£100,000 Portfolio charge - £400
Dealing: £7.50 per share trade.
Accounts: Sipp platform charge 0.3 per cent for first £250,000 and 0.2 per cent for next £750,000, with charges capped at that point.
Platform fees: Isa platform charge 0.4 per cent for first £250,000 but otherwise similar.
Range of assets: Oeics, unit trusts, offshore funds, UK shares including investment trusts and ETFs.
Tools and features: extensive analytical tools for asset allocation, benchmarking against a model, volatility and performance, as well as research notes covering managers' careers and performance history, and a selection of rated funds; tools to calculate mortgage payments, school fees, build a nest egg or plan for retirement; portfolio subdivision into customised 'baskets' which can be renamed at investor discretion.
Ready-made portfolios: yes, ready-made portfolio options, which are selected according to investor goals and risk appetite.
£100,000 Portfolio charge - £450
Dealing: equity trading £11.95 for up to nine trades a month, £8.95 for 10 to 19 and £5.95 for 20 or more. No set-up cost or annual fee for equities.
Accounts: Isas and Sipps have a platform charge of 0.45 per cent (explained in more detail below).
Platform fees: funds have an annual charge of 0.45 per cent for the first £250,000, falling to 0.25 per cent up to £1 million and 0.10 per cent for between £1 million and £2 million. No charge for anything over £2 million. Equities, ETFs and investment trusts charged 0.45 per cent a year, capped at £200 for Sipps and £45 for Isas, no charge for fund and share account.
Range of assets: cash, corporate bonds, gilts, ETFs, ETCs, passive and active funds, UK shares including Aim and overseas shares, investment trusts.
Tools and features: financial planning calculators, portfolio x-ray, live prices, charting tools, investment research and ideas, master portfolio, knowledge centre with 28 free guides.
Ready-made portfolios: yes, master portfolios, Hargreaves Lansdown multi manager funds and investment ideas.
£100,000 Portfolio charge - £600
Dealing: does not provide a share dealing service.
Accounts: account fees for Isa and Sipp same as the platform charge.
Platform fees: 0.6 per cent to £250,000, 0.55 per cent over £250,000, 0.5 per cent over £500,000, 0.4 per cent over £1 million and 0.15 per cent for more than £2 million.
Range of assets: 2,500 funds.
Tools and features: portfolio comparisons, portfolio x-ray, top 10 stocks, research centre; features to be made available on new website.
Ready-made portfolios: yes, five EasyIsa portfolios with six funds each.
Subscribe to Money Observer Magazine
Be the first to receive expert investment news and analysis of shares, funds, regions and strategies we expect to deliver top returns, plus free access to the digital issues on your desktop or via the Money Observer App.


text: FAQ's FAQ Home Find Answers ATCC® CRL-1730 vs. ATCC® CRL-2873 What is the difference between ATCC® CRL-1730 ™ and ATCC® CRL-2873 ™? Both ATCC® CRL-1730 ™, HUV-EC-C, and ATCC® CRL-2873 ™, HUVEC-CS, are normal cells from a human umbilical vein. Neither CRL-1730 ™ nor CRL-2873 ™ has been immortalized, therefore both cultures have limited doubling potential. Endothelial Cell Growth Supplement (ECGS) and unidentified factors from bovine pituitary, hypothalamus or whole brain extracts are mitogenic for CRL-1730. On the other hand, CRL-2873 was derived from CRL-1730 by initially passaging in tissue culture plastic flasks without additional growth factors like ECGS. Date Created07/17/2012 07:11 PM Date Updated02/04/2013 03:22 PM Most Popular Answers Huh7 cell line ATCC HUVEC lines Passage number vs. population doubling level (PDL) U-373 MG (ATCC® HTB-17) Converting TCID[50] to plaque forming units (PFU)


text:
If the stock closes down at least 4.46% today (as I write this it is off nearly 7%) Eli Lilly will suffer its worst one-day loss in more than four years, according to our resident statistical expert Robert Hum. If it were to close off more than 7.79%, Hum says it would be the stock's biggest one-day fall since Oct. 23, 2002--almost five years to the day.
After the closing bell yesterday the company put out a press release that said it was stopping patient enrollment in two small clinical trials for its experimental bloodthinner prasugrel.This drug was considered to be Lilly's most promising late-stage developmental drug and a potential billion-dollar-plus blockbuster. But beyond saying that it needed to amend the protocol of the studies it didn't offer any details about what exactly might be the problem--if, indeed, there is one.
But analysts and investors aren't waiting for an explanation. Many suspect that the drug might be so potent that it could be causing excessive bleeding in some patients. The results of Lilly's large prasugrel clinical trial are expected to be presented at the upcoming American Heart Association meeting on Nov. 4th. In the company's defense, one reason it might not be free to provide any more information is because it's under embargo by the AHA.


text:
In the clip above, Joe Biden tells a supporter that China can build Coal Plants over there, but there will be no Coal Plants built in America. Did he just hand the states of Ohio, Pennsylvania, and Michigan over to John McCain?
Tuesday, September 23, 2008
Too Late Biden! We Are Already Building A Clean Coal Plant Here in the US!!
In the clip above, Joe Biden tells a supporter that China can build Coal Plants over there, but there will be no Coal Plants built in America. Did he just hand the states of Ohio, Pennsylvania, and Michigan over to John McCain?
6 comments:
- Anonymous said...
This needs to be sent to newspapers all over PA and OH. They keep 86ing energy and prices keep going up. Good job.
- September 23, 2008 at 2:52 PM
- Anonymous said...
The Nancy Pelosi ("I'm going to save the planet") Democrats are passing up an oppotunity to create jobs with clean coal,nuclear energy and technolgy for oil recovery from oil shale.
The Al Gore wing of the party wants significant reductions in fossil fuel use in 10 years.The economic cost will be high with high prices and a deepening recession .
Please go to Americansolutions.com (a site associated with Newt Gingrich) and sign a petition about oil drilling to create American energy.The Nancy Pelosi energy bill will hinder the American economy !
I'm a chemist tasked with reducing formulation costs but petrochemical prices, as a result of high oil prices, are high priced . Inks,coatings,lubricants,fuel additives,resins,adhesives, and solvents all have petrochemical derived components and this should give one some idea of the inflationary aspects of rising oil prices other than high fuel prices.
The democrats aversion to nuclear power is astonishing as France obtains 60% of it's electricity from nuclear power plants safely.
WE cannot afford those rolling brown outs / black outs which occured in California some years ago due to increased energy demand and not having enough popwer plants. The Dems should realize that their plan does not create jobs !
- September 23, 2008 at 8:25 PM
- Anonymous said...
Great article !
The mainstream media probably won't talk about the Dems weak,and not comprehesive energy plan.
- September 23, 2008 at 8:30 PM
- Anonymous said...
OBama told people at a campaign stop in Pennsylvania that he is for clean coal.Will Obama take on Pelosi,Reid and Biden on the matter of clean coal ?
McCain will!
Also I checked out the site "Amercansolutions.com & signed the petition.
Global warming is an issue but our energy resource development can be done in a "clean" manner.
- September 23, 2008 at 8:41 PM
- DaveF said...
This is my take on the Global Warming issue. I apologize now for its length.
I am fairly open minded about issues. I generally try to gather information before forming an opinion on subjects I'm unfamiliar with. That doesn't mean I don't pay attention to things going on around me, and I do rely on common sense to make a lot of judgements. I do not look at everything as a conspiracy either. However, when it comes to relationships between the Government and researchers, environmentalists, scientists and corporations; I feel you need to take a devils advocate position. Why? Because typically the government likes to throw large amounts of money, our money, at perceived crisis' without enough data to warrant a sound decision. As proof, Fannie Mae and Freddie Mac debacle. Yes something needs to be done, but I do not believe we should jump off the cliff without first looking over it. It needs to be thought out so it fixes the problem; while protecting the people and country.
Back on topic. How many of the scientists touting Global Warming are experts, or at a minimum, have experience in Climatology? Who is behind the issue? I believe there are several groups who equally share the responsibility. Environmentalists, automakers and alternative energy manufacturers. I'll state my reasoning in a moment.
In order to get the ball rolling the group needed a spokesperson. In steps Al Gore. He is a known environmental change advocate. I believe in protecting the environment, so I do not see that as a negative quality. However, he appears to me to be possessed with a big ego and a severe need to be center stage. He was Vice President, but couldn't be President. He confesses to inventing the internet. He has a B of A in government. So, we know he is not an expert in Climatology or any other sciences. His best assets are his political experience and ties.
Now back to my reasonings. The environmentalists have made it their mission to save the earth from humans anyway possible. They learned from the past that violent protests and tactics often have a negative impact. But what if they push their cause through a likeable spokesman who already agrees with most of their agenda?
Automakers. What do we know? A large percentage of Americans are tired of high gas prices and want lower emissions to reduce pollution; especially in large metropolitan areas. The automakers are aware of this, so there is a focus on R&D to develop hybrid and electric vehicles. How much money is invested in this venture? What if there was someone who could get the Government to provide money, incentives through tax breaks, and the prospect of a large cash award to whoever develops the technology first? This same principle applies to Alternative Energy Developers and Manufacturers.
Are these good things? By all means, but, shouldn't this be their goal whether or not the government provides funding? After all, It is our tax money. The government budget is way over it's limit and growing. The economy is not real stable, etc, etc. I feel it is a form "Political Blackmail" for personal and monetary gain. And folks you and I are paying it!
I have included some info and links to allow for further consideration regarding this topic.
Fact Links on Global Warming:
I did not investigate the contributors of this link, but the ones with Climate background seem to agree and be consistent. The others may be outside that field of study, and I would not consider them reliable experts on climate. As for Al Gore, he has issues.
Original link to two above. Call me naïve, but doesn't hot water melt ice cubes?
- September 24, 2008 at 9:09 PM
- Anonymous said...
- September 27, 2008 at 1:33 AM


text:
The bear, unadulterated truth!
It appears to be a symptom of this multi-connected, always on-world we now inhabit that people are craving more and more 'experiences'. One upon a time, people traveled to various destinations in order to see what those destinations had to offer and in the main, those offerings were usually centred around the old stalwarts of … Continued


text:
Quick Links
The Lynx Center is an excellent place to learn about CU Denver. We are a resource center that provides all prospective and current CU Denver undergraduate and graduate students with quick and easy access to resources, referrals and solutions. Located on the first floor of the Student Commons Building on the corner of Larimer and Speer, the Lynx Center has qualified and caring staff on hand to answer your questions.
Our Vision:
Lynx Center
Student Commons Building1201 Larimer St, Suite 1107
Denver, CO 80204
Phone: 303-315-LYNX (5969)
Email: email@example.com
Useful Links:
Campus Maps
© The Regents of the University of Colorado, a body corporate. All rights reserved.
Accredited by the Higher Learning Commission. All trademarks are registered property of the University. Used by permission only.


text:
Wearing: head to toe Ashely Stewart
NYC has been in this weird transition weather from summer to fall the last few weeks where you can still wear shorts but can layer with a jacket. When browsing Ashley Stewart online I found a bunch of statement looks I knew I needed to get my hands on. One of which was this awesome mustard yellow faux leather moto jacket. The shorts came from a pair of bold printed leggings from the brand that I DIY'd into shorts and used the extra fabric to make a matching choker. I am OBSESSING over thigh high boots and Ashley is supplying me with the awesome options to fit a curvy calf.
Fun news! The brand is celebrating their 25th anniversary this month with an awesome contest..
Beginning Monday, September 19 through October 8, Ashley Stewart will host a contest to give away a once in a lifetime opportunity for one lucky winner and her bestie to win an all-expense paid trip to Los Angeles! The winner and bestie will attend the legendary We Can Survive concert at the Hollywood Bowl on October 22 featuring performances by Bruno Mars, Ariana Grande, Charlie Puth, G-Eazy, Meghan Trainor, One Republic and Pitbull with the opportunity to introduce one of the artists that will be performing and a V.I.P. meet and greet! Did we also mention 3 nights at the Loews Hollywood, celebrity makeovers, airfare and car service? Now how cool is that?!
All the divas have to do is take a photo or video and share how they survived and thrived in any aspect of their lives. All of the photos and videos will be hosted on the website at www.AshleyStewart.com/
IAmAshleyContest beginning September 19. The top 20 entries determined by votes will win a $50 gift card with the chance to win the grand prize of a V.I.P. trip of a lifetime!
xox Margie
Click through to check out some of my fave looks from the brand !


text:
Newton Free Library's Financial Literacy Resources
Newton Free Library's comprehensive list of Financial Literacy Resources includes links to helpful tools and websites. Categories range from debt calculations and college saving to housing and social security. The list also includes educational resources for ESL students and teachers.
Categories: Adult Education, English Language Learners, For Educators, For Program Administrators, Support Services
Contact Number: (617) 796-1360


text:
Filed under: Character Design, Design, T-Shirts, Uncategorized | Tags: arcade, b-movies, cats, Face to Face, factor viii, free-lance graphic designer, frochaux, frojax, graphic design, illustrations, john frochaux, pinups, punk rock, ramones, the ramones, zombies
The "Space Dykes…" piece got such a swell reception on my facebook account that I decided to go ahead and make it into a T-Shirt. They'll be going for $15 a pop at some local skateshops here in Panama; hope it does as well on the physical market as it did in loserville-I mean facebook.
Here are a coupla' pics of it. Oh, and just in case… to anyone interested, I accept paypal and I'm willing to ship internationally (contact me here firstname.lastname@example.com).
Remember folks: If you are interested in using any of the illustrations that appear on this blog, and/or have any questions regarding John Frochaux's (me) work and services please contact me at firstname.lastname@example.com.
All content and images displayed on this blog are the sole property of John Frochaux. Unauthorized use may result in legal action against the respective parties. All rights reserved 2010. So be kind, rewind.
Filed under: Character Design, Design | Tags: arcade, b-movies, cats, dominatrix, dykes, ed wood, factor viii, free-lance graphic designer, frochaux, frojax, illustrations, john frochaux, marky ramone, panama punk, punk rock, ramones, teens, the ramones, zombies
I can already smell the burning torches and the rallied mobs. That's the title of the post and I suppose I'll be sticking with it. I know its pretty offensive, so I'm gonna ask you to cut me a little slack. Female friends of mine and feminists I'm looking in your direction. C'mon, its not like I'm drawing Nazis or nothing-oh, wait… scratch that.
These two lovely ladies are part of a character design project I've decided to take on for an upcoming comic strip. Un PC and misogynistic as it undoubtedly is, I'm pretty sure that's also going to be the title of said strip, "Smokin' Hot Space Dykes from Planet Twat". Entertainingly presented in all its amateurishly drawn flare, I can promise you that it'll be funny in an offbeat and tasteless sort of way.
The story line is as campy and Ed Wood-a-fied as humanly possible; two smokin' straight girls (at least I think they're smokin') are lost in space, forced to depend exclusively on each other. Because of the circumstantial co-depencecy they've developed a slightly homosexual relationship over time. I'd say that this premise is absolute Pulp gold, Fredric Brown eat your heart out. I plan on making this strip more dialogue oriented than anything, but I won't skimp on the occasional zapping of aliens and other ne'er do wells. Oh, and don't think they're dressed to the nines in dominatrix gear for nothing, no sir, that stuff all has its purpose. You'll find out soon enough.
Remember folks: If you are interested in using any of the illustrations that appear on this blog, and/or have any questions regarding John Frochaux's (me) work and services please contact me at firstname.lastname@example.com.
All content and images displayed on this blog are the sole property of John Frochaux. Unauthorized use may result in legal action against the respective parties. All rights reserved 2010. So be kind, rewind.
Filed under: Design | Tags: b-movies, bibles, christians, concert, Face to Face, factor viii, free-lance graphic designer, frochaux, frojax, fun, Garry Larson, graphic design, horror, illustrations, joe strummer, john frochaux, punk rock, ramones, teens, The Far Side, the ramones, zombies
This one's a little different, I rarely venture into the realms of "mixed media" but what the heck.
An obvious wink and nod (is that possible, an "obvious wink and nod") to the infallible as well as impeccable Garry Larson format, here I leave you with "Every Sherif Gets Eated(sic) by a Hungry Zombie."
A colleague of mine asked why I forgot to give the Zombie a shadow; well, I didn't forget, it was very much intentional. Why? You ask. Seeing as how the Zombie looks somewhat vampire-esque, I'd say this is probably the re-animated carcass of some kind of vampire, hence the absence of a shadow. But what's a vampire/zombie doing out in the old west? Well, maybe you should ask yourself why you're trying so hard to find sense in an illustration of a Cowboy that is about to meet his maker through the aid of Zombie brain munching.
Remember folks: If you are interested in using any of the illustrations that appear on this blog, and/or have any questions regarding John Frochaux's (me) work and services please contact me at firstname.lastname@example.com.
All content and images displayed on this blog are the sole property of John Frochaux. Unauthorized use may result in legal action against the respective parties. All rights reserved 2009. So be kind, rewind.
Filed under: Design | Tags: factor viii, free-lance graphic designer, frochaux, frojax, graphic design, illustrations, john frochaux, marky ramone, panama, punk rock, ramones, teens, the ramones, viii
Here's a recent flyer series I did for Factor VIII; look closely and you might see Dee Dee Ramone somewhere.
I think I may be silk screening these at some point, I just gotta find the time to do it in. Free time has been somewhat of a rare luxury as of late, aw crud! Funny how this can really crap on your personal life… but that's a whole other blog entry I most likely won't get around to writing.
Remember folks: If you are interested in using any of the illustrations that appear on this blog, and/or have any questions regarding John Frochaux's (me) work and services please contact me at firstname.lastname@example.com.
All content and images displayed on this blog are the sole property of John Frochaux. Unauthorized use may result in legal action against the respective parties. All rights reserved 2009. So be kind, rewind.
Filed under: Uncategorized | Tags: cats, commie, crafty, craftyman, cynic, dawn, diy, dogs, factor viii, food, frochaux, frochaux blog, frojax, handyman, have a nice day, john frochaux, liza, much of it, new, overflowing toilet, ozzy, pale, plumber, pressure, ramones, rock, tips on tools, toilet, tool tips, toolboxes, tools, viii, wood working tips
Just last week my toilet attempted to take a midnight wiz all over my apartment and I was brought down to my knees (literally) to tightly hold a metal tube that had been punctured by fluctuating water pressure for the greater part of an hour. Fifty minutes and a nightmarish leg cramp after, the plumber showed up and fixed my disobedient plumbing with the daintiest twist of a wrench. Our minuit affair ended in a $100 plumbing bill. After an otherwise restful night, I decided that some changes had to be made.
There comes a time in every man's life when some things need to be decided upon; things such as a insurance providers, appropriate coverage, weight loss, dieting, 70's Ramones vs 80's Ramones, arcade cabinet building, and marriage. But before any of the aforementioned queries can be tackled, a man must have the correct tools to successfully run life's four-minute mile; in other words what is a man without tools? I'm hardly speaking metaphorically here folks, I don't mean tools as in knowledge and/or intellectual well roundedness when standing on one of life's proverbial cross roads. I'm talking about the galvanized and iron foundered tools you buy at the hardware store. Tools that, when used skillfully, posses the power to turn you into the handiest of men.
Today I crossed one of life's portals, thus leading me into another facet of pseudo-adulthood. Today I maximized an aspect of my life… today I purchased my first complete toolbox, and I'll point out that this wasn't a pre-assembled set, no sir! My toolbox was strategically hand picked tool by tool by yours truly. Carefully tailored and designed to cater to any household situations and/or malfunction that may need the attention of variant degrees of brawn, craftiness, and of course tools.
While shopping for said toolbox, I took some things into consideration like; durability, usability, and stainless steel vs. other metals (i.e. When threatening someone with a hand-tool, a stainless steel wrench has more of an effective visual effect than a metal one because of the former's polished finish. If faced with having to actually carrying out said threat you run the risk losing your tool; a metal wrench has a lower opportunity cost than one made of stainless steel. Conclusion: stainless steel is best for threats and impressing other kin folk, and in comparison metal is more expendable as far as cost go).
Once I had chosen all of my pliers, socket wrenches, and general tool-ery I made my way to the front checkout a paid. As I walked to the car toolbox in-hand, my innards rewarded with the feeling you get when you know you've acted efficiently. My gut echoed "John, this was a wise purchase".
Upon my arrival at the apartment I praised myself for having done well, and proceeded to call family members and friends alike to indirectly inform them of my current status of Toolbox Owner/Craftyman.
Filed under: Uncategorized | Tags: arcade, arcades, cat food, catlevania, craft, dragon's lair, emulators, fun, fun games, game images, game roms, gamers, gaming, geek, geek games, geeks, groovygamegear.com, hugo chavez, m.a.m.e. cabinet from scratch, mame, neo geo, nerd games, nintendo, old video games, pet food, punk rock, punk rock games, ramones, reanimation festival, rebuild, roms, samurai showdown rom, stuff to do, the re-animation festival, video gamer, video games, vintage games
The last couple of months, I've been browsing around the net looking for information about the history of video games, which now I've found out that according to some dates back to the 1880's. Over the last months I've run into my share of interesting articles as well as manga-enthusiast (read: nerd) ridden message boards. But then again, who's the one researching video games, I guess that alone would completely take away my right to finger-pointing and name-calling.
I wouldn't catalogue myself as an avid gamer or a video game enthusiast, but over the last couple of weeks I've learned that I still have a soft spot for some of the games I played as a kid. Back then, a trip to the arcade was an incredible experience, as well as something that could only be done on weekends because an entire day had to be dedicated to said excursion. No weekend mall visit would be complete without a gingerly stroll around the arcade. It was always an adventure; everything from avoiding the "drug dealers" your parents warned you about, to checking out the newer games and getting in line to play two rounds of Street Fighter with the spectacled kid with the lightning fast hands that would beat everyone all the time. Even when you blew all your money it was still fun to walk around an otherwise seedy place just to watch others play. It was noisy, the carpet smelled, sometimes you'd get into minor scuffles with other kids, but it was always fun and always the best place blow your allowance at.
I still remember the first time I saw a NEO GEO cabinet with Samurai Showdown; I was mesmerized by the graphics, the colors, the gigantic (at the time) characters, and most importantly the violence. I recall how awe struck I was by the zoom-in zoom-out feature that had been incorporated to the game, something that was considered groundbreaking at the time. From the late 80's to the early to mid-90's, there was an explosion of pretty cool coin-op machines in every mall. Back then arcade games didn't translate very well to home consoles because of their technical specs, so the only way to get truly impressive graphics and velocity was through a stand up coin-op cabinet. As a child I constantly fantasized about having one of these machines at home. Just a couple of days ago an opportunity to make my dream a reality presented itself.
During one of my recent strolls through Nerd-Ville, 14 years after the release of Samurai Showdown, I learned about this thing called M.A.M.E. (Multiple Arcade Machine Emulator) at first glance this seemed like some jack-assed japanese animation geek fest. You can't blame me for using harsh language, based on recent personal experience, 90% of the time I would come across any kind of interesting information in regards to old video games it was always hosted on a web page or forum that contained some of the pettiest, most hair brained discussions I've read in years. Well, back to M.A.M.E. (pronounced maim). In a nutshell, M.A.M.E. is an arcade emulator that runs rom images of arcade games on a computer; with a decent PC you can play old arcade games at home, that simple. Some folks have taken this a step further by building arcades from the ground up, adding special customized features to cabinets in order to show them off via internet to their fellow nerds at a later date. Some folks buy used cabinets from arcades and just stick a PC in them after slightly revamping the outer shell, other burlier and craftier folks build cabinets from scratch and wire them in the same manner. There's an entire community of people all over the world that have embraced M.A.M.E., hell I think you may just call it a movement of sorts.
After really looking into M.A.M.E., I asked myself why I hadn't found out about this and why hadn't I gotten into it? After reading up on the materials that I needed and just how difficult it would be to carry out this project, I decided that I had to get into it. I did. I've decided that I'm going to build an arcade for me and my friends; I'm pretty sure I can pull this off. Remember me blogging about giving myself little tasks an entry ago? Well, this is the new task, "John Takes On Building An Arcade From The Ground Up". As of today I've already purchased the arcade parts I'll be needing (push buttons, joysticks, wiring, cables, etc.) from the fine folks at groovygamegear.com, a sound card; I spoke to a friend that sells computers and he's going to help me put a good clone together for me to run M.A.M.E. on, a Happs (expensive arcade supply store) brand coin-door from ebay, and several other components to make my monster come to life before the end of January. This weekend I'll be buying the MDF for the cabinet, hopefully I can get it cut and drilled before Sunday, we'll see.
I will be doing everything myself and it will be documented right here on the blog. I'm sure this'll be a real cool time, time to bring out the power tools… well, I'm sure someone'll lend me some.
Filed under: Uncategorized | Tags: 1977, 77, cats, drums, everything else, factor viii, frochaux, frojax, joe strummer, joey ramone, john frochaux, johnny ramone, Linda Stein, marky ramone, murder, oldschool punk, panama punk, paradiddles, pizza, punk, punk rock, punks, ramones, rock, rock and roll, sex pistols, Sire Records, the damned, the ramones, tommy ramone, viii, youtube
During my daily news-read, I came across this very disturbing article about Linda Stein's (Ramones' manager at one point) murder, something I hadn't the slightest knowledge of.
Linda Stein worked with the Ramones for many years before going into real estate, and was responsible for booking the band's infamous appearance in London's Roundhouse in 1976, which turned out to be one of the most pivotal moments in the band's career, if not the most; an event that defined the future of punk rock. I
won't go into a long-winded diatribe about the origins of punk rock, but I will say this: The Ramones created and defined punk rock, Malcolm Mclaren just found a way to massively cash in on it.


text:
Can the Japanese make espresso? In a country so committed to tea with a choreographed ceremony that considers every movement and gesture – can there be a place for the art and science of Italian caffe? Surprisingly Japan is considered to be one of the largest consumers of coffee in the world with a passion and love for coffee that is spreading more and more.
エスプレッソ , the Japanese word for espresso, is becoming so popular it's not uncommon to see coffee shops and espresso bars amid the neon and buzz of Tokyo and the shrines and temples of Kyoto. Although the Japanese coffee culture may be in its embryonic stages, like a chrysalis waiting to become a butterfly the Japanese are embracing a new way of thinking about coffee and steamed milk.
With creative methods of brewing as ceremonial as any tea ritual, the Japanese style of making and drinking coffee is reflected in the Hario syphon coffee system. Not quite the la bella vita crema of espresso but made well enough to transport you to a zen-like state of coffee satisfaction.
Known for making high quality heat-resistant glass, this Japanese company has been manufacturing glassware since 1921. With systems and vessels that look like beakers in a chemistry lab yet combined form visual works of art, Hario's coffee (and tea) brewing systems produce a rich bodied flavorful drink with precision and beauty.
*watch this video on syphon coffee from Intelligentsia


text:
Eli's flat head for the whole first year of his life, I worked hard to keep Carson's head round.
Saturday, August 11, 2012
Brotherly Bonding
Eli's flat head for the whole first year of his life, I worked hard to keep Carson's head round.
6 comments:
- Eric and Justine said...
It is fun to see eli already playing with his little brother. That is one cute pic of Carson on his tummy!
- August 12, 2012 at 5:24 AM
Again. Too cute. Come visit anytime :) well have another car soon so ill have to come up too
- August 12, 2012 at 8:59 AM
- Rebecca said...
I also love the picture of Carson on his tummy. Adorable!
It was fun to see the brotherly love in action last week. I'm still waiting on the post that shows Eli's "cousinly love" toward Spencer...
- August 12, 2012 at 9:07 AM
- Kim said...
And here's another vote for the Carson tummy time photo being so cute. Loved all the poses of Eli holding Carson. Sweet, cute and funny!
- August 12, 2012 at 2:53 PM
- jlthomas said...
If you ask me, I think Eli looks like he has things under control enough that you could probably leave him in charge for a short date. Probably not dinner and a movie yet...but dinner alone is probably fine.
- August 12, 2012 at 6:45 PM
- jlthomas said...
Love the tummy picture too!
- August 13, 2012 at 3:36 PM


text:
HH Fitness is in its 3rd phase of training at the Movement & Performance Institute for the Metabolic Accelerator Program (M.A.P.), these is our large group personal training sessions. When we use finishers within our training program we make sure the protocol being used is less than 12 minutes, with the average finisher being no more than 5 minutes . When this component of training is placed at the end of a training session it becomes the final exclamation point to your workout. This sets the tone for the rest of the day.
One of our finishers this phase is the Leg Crank Finisher. The Leg Crank only requires you to use your body weight. Body weight training may be the oldest and one of the best ways for resistance training. I first learned about the Leg Crank series about 8 years ago and have incorporated variations into the training programs for clients at HH Fitness. I first learned about the leg crank series from educational materials put out by JC Santana with the Institute of Human Performance (IHP). The Leg Crank Series is great if you need at great training session, but are pressed for time, space, and equipment. It also works great if you have a training run scheduled, but are unable to get your run in due to bad weather or any other variable.
What is the Leg Crank Series?
The leg crank series is a vicious serious of exercise that you may create a true love-hate relationship with. You will be challenged not only physically, but mentally as well. To make it through the leg crank series you will create mental toughness. The Leg Crank is a series of four exercises:
- Speed Squats
- Alternating Lunges
- Alternating Jumping Lunges
- Squat Jumps
To perform Leg Crank series you will perform the 24 repetitions of the speed squats, then 12 repetitions per leg of the Alternating Lunges, followed by 12 repetitions per leg of the Jumping Lunges, and finish it off with 12 repetitions of the squat jumps.
To get the biggest bang for your buck you may want to perform the Leg Crank series up to twice per week. You will want to progress slowly as you begin this series. You may find you need longer rest during the first few weeks of adding this to the end of your training sessions. Our phases of training are 6 weeks long, giving our clients time to build up to taken on the Leg Crank Series at greater intensities as we move through the phase. However, based on your fitness level you may find your rest may need to be longer or shorter to get the physiological demands needed to survive the leg crank. Here is a sample we would recommend to our clients for the Leg Crank finisher:
Level Sets Rest between exercises Recovery between sets
I 2-3 circuits 30 – 60 seconds 2 – 3 minutes
II 4-5 circuits 15 – 45 seconds 60 – 90 seconds
III 5-6 circuits No Recovery No Recovery
Please note that the above samples are just that, a sample plan. Your own fitness level may be between a level 2 & 3. You may be able to perform the circuit non-stop for the desired repetitions, but may need to rest up to 60 seconds prior to starting the next cycle. D what you can, and not what you can't!
Committed to your health,
Heath Herrera, M.Ed., CSCS, YFS1
Head Coach
HH Fitness, Inc.


text:
Musical brothers Adrian and Justin Anantawan want kids to know special education needs don't define them
Violinist Adrian Anantawan and his family talk about using music to help children with special education needs
By Young Wang
Violinist Adrian Anantawan was in Hong Kong earlier this month to perform in the concert, To World, With Hope, with the Metropolitan Youth Orchestra (MYO) and four local autistic students.
The acclaimed musician, who was born without a right hand, has been taking his story all over the world and working with students with special educational needs (SEN).
"[When] you're playing a concert, you're going to affect someone for a moment, but to spend a longer amount of time with some students can provide a longer, lasting, deeper impact. Education provides that vantage point," said the 33-year-old, who also performed in Hong Kong with MYO and three of the same children in March.
Canada's bionic violinist, Adrian Anantawan, tells Hong Kong students about overcoming challenges to live your dreams
His younger brother Justin Anantawan, 29, joined him on the more recent trip and staged his own concert with MYO, The Sound of Love. The show featured members of the Hong Kong Association of the Deaf's Children Hand in Hand.
Justin has spent time working with deaf students in Africa over the past eight years and, for the past two years, was a dedicated teacher at a school for the deaf in Gambia.
Three days before his concert, Justin told Young Post that he wanted to share his experiences in Africa with Hongkongers to change the way they view disability. Rather than seeing it as something to pity, it should be regarded as a difference that should be celebrated and embraced. Justin has been teaching deaf children baking, photography, English and music. "I teach them songs in sign languages ... ironically, I taught a little bit of taiko drumming [in Kenya] but the kids were better at drumming [than me] because it's part of their music," he laughed.
Justin had wanted to go to Africa since his teens. He first visited the continent when he was 21 and stayed there. The musician's mother wasn't initially too keen on Justin's plan.
"I didn't expect him to go for two years straight. All parents [would] find it a little bit long because they miss their kids, period," said Maria Yim-Chu Anantawan.
"But ... he's safe and sound and he still has two arms and two legs."
Violinist Iskandar Widjaja p(l)ays it forward by coaching disadvantaged young musicians
One second later, she turned to Adrian, and could barely contain her laughter. "I'm sorry, you're fine, too."
Adrian hopes to deliver one message through his music — "never give up".
"Any time you make it personal, you have an opportunity to reach a student in a way that makes that relationship less about one person telling [another] what to do," Adrian said. "Whatever [the message] is that you're trying to give, personal stories are often the best way for people to learn, because they're very much about the person rather than the textbook."
Behind the (pitch-black) scenes of the popstar-filled Concert in the Dark, organisers don't let disability slow them down
Surprisingly, Adrian didn't find working with the autistic children too different from working with other musicians – they try to listen to each other as much as possible, work out what needs to be blended together and are "always receptive to feedback".
Although it helped to have music as a communication tool, Adrian believes every child has a preferred method of communication, which requires a lot of thought and care.
"You have to read the communication; some actually might [be open and] give a lot," he said.
HKDSE high scorer Cherry Ho didn't let brittle bone disease or numerous hospital visits keep her dream of studying law
As someone who believes in giving back to society and who has raised her children to do the same, Maria wants to assure special education needs families that there is support for them. "SEN families are just another family, a lot of things are more similar than what people think," she said.
A mother of children who required special support growing up, she understands how concerned parents of SEN children can be. But she wishes she hadn't spent so much time worrying about the worst-case scenarios she imagined for her own children. "Nintey-five per cent of those things never happen," she explained. "Spend 95 per cent of your energy living in the moment. Don't forget that the family has a warmth in there that's worth everything."
Proceeds from the Anantawans' concerts will go to MYO's Music Angel Programme, which offers training and performance opportunities to local autistic students. A final fundraising concert will be held on November 19 with Nick Vujicic, the Australian motivational speaker born without arms or legs.
Edited by Ben Young
log in register or Login with facebook