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SEFTON charities will get a share of £25,000 from the Mayor of Sefton's Charity Fund.
It is largest amount ever raised by the fund - a whopping £9,000 up on the previous year.
The amount, which was raised during Councillor David Pearson's mayoral year, was swelled by the local authority's new staff lottery scheme.
Charities to benefit from the 2003/2004 Mayor's Charity Fund included: 11th Sefton East Scouts; Rampworx Youth Village 2000; 2nd Sefton East Cubs; Old Roan Pensioners Club; Maghull & District Monday Club; Maghull Pensioners Association; Maghull Young Adults Social Club; Alison Hallahan; 7th Sefton East (Melling) Scout Group; Daniel Williams Fund Appeal; Father Bierne Memorial Fund and Melling Pensioners.
Kind-hearted employees have been contributing £600 each month to the Mayor's Charity Fund through the lottery which was introduced early 2004.
Donations are received allyear-round and five charity committees also stage fundraising activities.
The biggest event of the year, the Mayor's Charity Dinner, brought in a staggering £7,000.
Sue Powell, fund co-ordinator, said: "We are delighted that Sefton charities will share £25,000. This is a superb total and we are delighted that so many Sefton organisations will benefit.
"We want to say a big thanks to everyone who contributed to making the Mayor's Charity Fund such a terrific success.
"We aim to raise an even larger amount during Cllr Clifford Mainey's year in office and we are already off to a good start."

subset: commoncrawl


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Creating swap file on an USB drive already being used as an extra storage option.
Amyanshu Jenamani
I configured my onion omega2 to boot from an external USB device [8GB]. Now I want to increase its RAM. Will I just follow the documentation or I have to do something extra?
Gabriel Ongpauco
Hi @Amyanshu-Jenamani ,
You can increase the available memory by creating a swap file on the USB drive. We have a guide on this here: https://docs.onion.io/omega2-docs/extending-omega-memory.html
Since you are already booting from the USB drive, I advise you back up your data before attempting this.


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I'd like to share a project I've been working on. DroneDyno is an automated brushless motor test stand.
I want to be able to test my motor/prop/ESC combinations and learn more about all of them – on my workbench, not in the air!
It uses an ESP8266 controller which is like an Arduino but with WiFi. It has an interchangeable motor mount, a current sensor and a load cell (scae) to measure thrust and current (amps) consumption for different throttle settings.
The controller handles everything – it throttles the motor up through a range of values recording thrust (in grams) and current (in amps) then uploading the results to a spreadsheet on Google Drive.
The project is still a work in progress the code is a mess but it works well. Once it's cleaned up I'll post it on GitHub along with the 3D design files.


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'Powerful Recovery' as Sales Jump 11.8% in February
Spring hath bloomed… it's that time of year again!
Provided by Dave Skow
Loan Officer
Your email address will not be published.
Get a Free Guide
My experience working with Sarah Jullion in the sale of my rental condo was superb! Her knowledge and expertise in the Seattle/Bellevue real estate market, combined with personal attributes such as tenacity, reliability, resourcefulness and charm make her a top-notch real estate agent. Ms. Jullion has a terrific work ethic – she was consistently available to me and gave me as much time and effort in selling my small condo as she would have given the owners of more expensive properties. She readily assisted me in solving problems that arose throughout the entire process, including the pre-listing phase, which involved dealing with a difficult contractor and an unprofessional property manager. And, I obtained a "top-dollar" sales price due to Ms. Jullion's excellent market analysis and knowledge. I would highly recommend her as an agent! —Marilyn Devaney
© 2019 Sarah Jullion Real Estate.
Made with by Graphene Themes.


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Automotive Detroit
Automotive Simulation is a lot more crucial than ever in vehicle engineering with the innovation surge currently taking place in the industry. Take a look below.. and enjoy some genuinely creative masterpieces of remarkable automotive paintings & fine art. The number a single location on the web for information on transmission repair , transmission issues , and reputable Transmission Repair Shops.
Nevertheless, there is a limit to how simple it is to a button making use of the touch screen keyboard will be compared to getting a genuine physical keyboard. Monster takes the job board to the next level by integrating potent technology and more than two decades worth of experience into their platform. Following the process described in your repair manual can assist you fix the method. It lubricates all the inner workings and moving components of a automobile engine's crank case to reduce heat-causing friction. It that does not perform you could require to purge the tank, remove the leaky component and put some automotive sealant on the threads to form an airtight seal. Low-cost digital multimeter in your nearby electronic components shop, hardware shop, division shop or on the internet. The year is about 2200, so technologies has changed, and we can see that in these automobiles.
We organised once more the AUTOMOTIVE HUNGARY JOB FAIR in cooperation with Our exhibitors could participate in this event for free of charge and could give gives for jobs, and visitors could get an overview on human demand of the automotive business.
Usually of classic style with a low seat, pull-back manage bars, fancy paint and lots of chrome. You can use dimensional fabric paint or any other type of 3D paint that comes in a squeeze bottle or tube with a pointed applicator-type tip so you can squeeze out lines of paint. NOS: 1) New Old Stock: old parts that are still in stock 2) Nitrous Oxide System. Then I utilized that new shade to paint the insole, including the edges that showed all the way around. He carried along his tablet and headed toward the office of the owner and operator of Goulding Automotive America, Todd Goulding. I have done bachelors in Engineering(Mechanical) and have two years of experience in automobile market in the fields of design, study, high quality, purchase and marketing and advertising. This job doesn't require special tools (except for an oil filter wrench) or technical knowledge, and you can locate the correct procedure for your model in your automobile repair manual.
HondaCare is an great warranty extension business to function with, as lengthy as the repair is legitimate, they will cover it. Thanks for you feedback Dave, I actually appreciate it. I've had to go via the dealership before and even although I knew I was getting ripped off, there was absolutely nothing I could do about it simply because they were the only ones who could get the parts to repair my vehicle. If all eight tests are passed an ASE Master Technician Certification is awarded.


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MARINETTE – Lori Saunier is one of nearly a dozen parents who have expressed their displeasure over a game played at Marinette Middle School. News in
"This kind of stuff, I mean, this can't happen again. These are our little kids. We're parents. We should've been protecting them. You should've gave us the benefit of the doubt of contacting us," said Saunier, mother of 7th grade student.
On Wednesday, fifth through eighth grade students played the game called "Cross the Line".
Parents say their children were asked personal questions like, do your parents drink and has anyone in your family been in jail?
Students were also asked to step forward if they answered yes to any of the questions.
Neither the school principal nor the district superintendent would answer questions on camera, but in a written statement, the principal said participation was not required and students could have said no.
However, parents claim their students told them that if they didn't participate, they'd receive an in-school suspension.
Sarah Maitland was one of the students who played the game.
"She asked if you ever wanted to commit suicide to step forward and then after that she asked if you ever experienced or wanted to cut, to step forward," said Maitland.
The school says the activity is a part of a bullying prevention program.
A few parents met with the superintendent, the principal and the assistant principal Friday morning to express their concerns with the game.
"They basically told us that all the students were lying…all the students got together and planned it out and if they weren't lying, it was all misperceptions. They didn't specifically say do your parents do drugs," said Amanda Fifarek, mother of 7th grade student.
School administrators said, "The intent of the activity was to build stronger, more respectful relationships among students."
However, parents said they believe it actually makes it easier for students to bully each other.
"It was too personal. It's just things your kids don't need to be disclosing to other kids," Fifarek said.
On Friday the school sent home a letter explaining more about the game and why it was used, but the parents who oppose it say it's not enough. They still want answers.
Parents say they were not told that the game was going to be played.
The school says if there's another such activity, it will let parents know ahead of time.


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Are there any workarounds to enabling the Buddypress registration form to work within upfront scribe theme?
Or is there a way to use a different plugin like, membership pro to allow users to create the BP profile?
I am using a multisite. But not wanting to necessarily have users create their own blogs.


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There's a good article at ClickZ on the sticky situation of corporate politics and SEO for bigger companies. "When Corporate Politics and SEO Collide". It emphasizes the importance of the unique communication needs of a bigger company with interdepartmental participants affected by a SEO project. Project management skills are as important as SEO implementation skills.
This sentiment is reinforced by Stuntdubl's post yesterday: "The best "SEO's" are really a culmination of a variety of very diverse skills brought together to improve a business or organization's marketing performance in the online arena. Top SEO's are "project managers" and meta-webmasters".
How true. Just yesterday I was meeting with a client that's a fairly large organization who's webmaster left a bit of unintended "disinformation" behind. We're speaking with/educating various department heads now to bring everyone together and refocus on strategy and objectives rather than the implementation of tactics "because the competition is doing it" or "because our webmaster said that's what we should do". Rankings are one small step to the real goals of improved brand visibility and increased sales.
MarketingProfs has a good article about that today. The Myth of Rankings: Beyond Search Engine Optimization. "A consistent problem with the "ranking-centric" mindset is that it doesn't reflect a powerful rationale for getting involved in SEO. Where is the true business case? What tangible results are desired? "
Business, marketing, communication, project management, technical skills (coding and often server side), copy writing, web design, research, analytics and even public relations on occasion. All these skills are what make up a good SEO. These are important skills for any size optimization project, but particularly with larger companies and corporate SEO projects.


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Table of Contents
Definition and Pathogenesis of Diverticula
True and false diverticula
Diverticula are wall protrusions of hollow organs, whereby a distinction has to be made between "true" and "false" diverticula. It pays to learn the definitions, as they usually come up in exams.
True diverticula
In case of a true diverticulum, all wall layers are affected, even the muscularis. The protrusion often arises through tension from outside, in the course of scarred or inflammatory changes that can be found e.g. with tuberculosis or lymphadenitis.
False diverticula (or "pseudodiverticula")
In this case, only mucosa and submucosa evert to the outside through a weak spot in the muscle layer. The reason for this is increased intraluminal pressure.
With respect to the esophagus, the different diverticula can be classified on the basis of their location, as well as their "true" or "false" nature as:
Traction diverticula
They correspond to the above-mentioned "true diverticula" and are usually found on the level of the tracheal bifurcation. They are therefore also referred to as bifurcation diverticula or para-bronchial diverticula.
Pulsion diverticula
They correspond to the above-described "false diverticula." Predilection sites are the following, muscle weak points of the esophagus:
- Laimer triangle (= longitudinal muscle-free zone on the upper esophagus).
- Killian triangle (= muscle weak area between Pars obliqua and Pars fundiformis of the cricopharyngeal muscle of the dorsal hypopharynx): Strictly speaking, this is really a diverticulum of the hypopharynx, although it is usually dealt with in context with the esophagus. Diverticula in the area of the Killian triangle are also known as Zenker's diverticula.
- Above the diaphragm: This is called an epiphrenic diverticulum.
Epidemiology of Zenker's Diverticulum
Zenker's diverticulum is the most common representative with 70% and mainly affects older men, followed by traction diverticula with 20% and epiphrenic diverticula with 10%.
Symptoms of Esophageal Diverticula
Dysphagia and regurgitation
Especially large diverticula bring on complaints. Patients complain of dysphagia, retrosternal pain, feeling of pressure and nightly regurgitation of undigested food residues. The latter is connected to risks of aspiration and pneumonia. Deposition of food residues in the bulges leads to fetid halitosis. Some patients describe a "gurgling" sound while drinking.
Diverticula rarely become inflamed, bleed, perforate or form fistulas.
Diagnosis of Esophageal Diverticula
Esophageal bolus swallow test is the method of choice
The diagnostic method of choice is an esophageal bolus swallow test. Due to the possible presence of a perforation, it is recommended to use a water-soluble contrast medium, as there's a risk of mediastinitis or peritonitis upon exit from the esophagus when using barium. X-ray images most often clearly show the accumulation of a contrast agent in the protuberances, and allow a precise differentiation of the diverticula according to their location. Traction diverticula usually feature "ear-like" outgrowths, while pulsion diverticula are mainly sack-shaped.
In order to be able to exclude other causes for the symptoms (carcinoma?), an endoscopy should always be carried out as well. However, care must be taken as the mucous membrane in the area of diverticula wall is particularly prone to perforation.
Differential Diagnoses
In terms of differential diagnosis, one should particularly consider esophageal carcinoma!
Therapy of Zenker's Diverticulum
Surgical measures for Zenker's diverticula
Diverticula can be treated surgically. However, this is only indicated for Zenker's diverticula and rarely for larger and symptomatic epiphrenic diverticula.
Review Questions
The correct answers are located below the references.
1. Which statement is correct?
- The Zenker's diverticulum is an epiphrenic diverticulum.
- Para bronchial diverticula are among the pulsion diverticula.
- Traction diverticula are always false diverticula.
- An epiphrenic diverticulum is always a real diverticulum.
- A bifurcation diverticulum is a traction diverticulum.
2. The Zenker's diverticulum…
- …is not as well represented as other diverticula with 20%.
- …is located in the area of the Laimer triangle in the upper esophagus.
- …shows a contrast agent-filled bulge in the area of the hypopharynx during the esophageal bolus swallow test.
- …is treated surgically only in rare cases.
- …rarely causes symptoms.
3. Which statement about the pathogenesis of esophageal diverticula is true?
- In the case of a false diverticulum, all wall layers are affected by the protrusion.
- True diverticula are mostly a result of increased intraluminal pressure.
- In true diverticula, mucosa and submucosa evert through the muscle layer.
- Traction diverticula can result from a tuberculosis infection.


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Romulo Yanes
One of our test-kitchen assistants, Herta Guhl, sold us on these Polish fried dough cookies. A little powdered sugar makes them irresistible.
- Yield
- Makes about 4 dozen cookies
- Active Time
- 1 1/4 hr
- Total Time
- 1 1/4 hr
- 3 1/3 cups all-purpose flour plus additional for dusting
- 2 teaspoons baking powder
- 1/2 teaspoon salt
- 1 stick (1/2 cup) unsalted butter, softened
- 1/3 cup granulated sugar
- 1/4 cup sour cream
- 3 large eggs
- 1/2 teaspoon grated fresh lemon zest
- 6 cups vegetable oil for frying
- 1 1/2 cups confectioners sugar
- Special Equipment
- a pasta machine; a deep-fat thermometer
- Whisk together flour, baking powder, and salt in a small bowl.
- Beat together butter and granulated sugar in a large bowl with an electric mixer at medium-high until pale and fluffy, about 2 minutes in a stand mixer or 4 minutes with a handheld, then beat in sour cream, eggs, and zest. Reduce speed to low and add flour mixture. Mix until just combined. Form into a 2-inch-diameter log.
- Set smooth rollers of pasta machine at widest setting. Cut log crosswise into quarters and keep 3 pieces covered with a kitchen towel (not terry cloth). Flatten remaining piece of dough into a rectangle about 1/3 inch thick. Dust with flour. Feed through rollers. Fold in half crosswise and feed through rollers 8 more times, folding in half each time. Dust with flour if sticking.
- Turn dial to next (narrower) setting and feed dough through without folding. Continue to feed dough through without folding, making space between rollers narrower each time, until the second to last setting is used.
- Cut rolled-out dough into 5- by 2-inch rectangles. Make a 1-inch lengthwise slit in center of each rectangle. Pull one end of strip through slit, forming a loose knot. Transfer to a lightly floured baking sheet.
- Heat oil in a 5- to 6-quart heavy pot over moderately high heat until it registers 370°F on thermometer. Fry knots, 4 at a time, turning over once or twice, until golden, about 1 minute per batch. Transfer with a slotted spoon to paper towels to drain.
- Turn off heat under oil and roll out and form knots with remaining dough. Return oil to 370°F before frying rest of knots.
- Dust cooled cookies with confectioners sugar.
Cooks' notes:
· If you don't have a pasta machine, roll out dough on a well-floured surface with a well-floured rolling pin to less than 1/8 inch thick. · These cookies are best the day they're made, but they can be kept in an airtight container at room temperature 1 day.
Related Video
Nutritional Info
- Calories41
- Carbohydrates5 g(2%)
- Fat2 g(3%)
- Protein0 g(1%)
- Saturated Fat0 g(2%)
- Sodium27 mg(1%)
- Polyunsaturated Fat0 g
- Fiber0 g(0%)
- Monounsaturated Fat1 g
- Cholesterol13 mg(4%)


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Elegant MicroWeb provided WordPress development service to a real estate solution provider in USA. The client is into real estate industry and works on substantial property acquisitions which involves large scale developments. WordPress Development specialist from Elegant MicroWeb developed the responsive portal integrating the theme provided by the client.
- Responsive Thumbnail Slider – Manages any number of images into the responsive slider
Tools and Platforms
- Platform : WordPress Development Framework
Technical Competencies
- WordPress Development
- WordPress Responsive Design


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GroHealthy Shea & Coconut | Product Review
If you have read my post from last week, you will see that i received my first box from treasure tress. My box contained 5 products from GroHealthy Shea & Coconut Range.
This is a brand that i haven't used yet, but have been seeing alot of on instagram the past few months and so i was quite excited to see that my box was full of the range.
The products all contain 3 main ingredients which together, are a triple threat!
Coconut: Moisturises, adds shine & helps promote growth
Shea: Nourishes roots, soothes scalp
Omega 3: Helps rebuild, strengthen & protect hair from within
I have been really impressed with the range so far, but i will break it down product by product below.
Curling Custard:
"Create long-lasting, shiny spirals and goregous curls. "
"Apply to damp hair and work through from the roots to ends. Use fingers to elongate curls."
Moisturizing Shampoo
"Experience the rich, luxurious lather of Shea & Coconut Moisturising Shampoo as it cleanses hair, soothes the scalp and protects hair colour. Cleansing without stripping away your natural oils, for soft, silky hair."
"Apply to wet hair, massage into lather and rinse thoroughly. Follow up with Shea & Coconut Moisture Rich Conditioner."
We curly girls, i think are all agreed on how we feel about Shampoo. To try a new brand can be scary as we've all had a bad experience or two. The bottle says that this shampoo is free of Sulfates, Parabens, colourants, Mineral Oil etc. I know a lot of us like shampoo with sulfates, but for me a sulfate free one works best, and so knowing this was safe to use on my hair was great. It has the same smell as the curling custard, and is quite thick and creamy in consistency. It does create a lot of lather, which i mentioned in my last product review i used to worry about, but again like with the ORS Black Olive Oil, it was actually great on my hair. I didn't get that straw feeling after using this shampoo at all, and am really happy with the results.
Moisture rich conditioner:
"Its time to treat your hair and scalp to something special and nourishing. Pamper them with essential oils for nourishment and growth."
"After shampooing, towel blot hair to remove excess water. Use ample amount of conditioner to saturate hair and scalp. Comb through roots to ends with a wide-tooth comb. Cover with a plastic cap for 10-15 minutes. Rinse well."This conditioner contains Castor oil, which is a key ingredient in getting your hair to grow. I expected the conditioner to smell the same as the other products but i was wrong. It has the same coconut smell, but it also has hints of like tea tree oil. I may be wrong as i didn't see it in the ingredient list, but that's what the smell reminded me of. I liked this conditioner alot. My hair was so smooth afterwards, and i will be using this in my routine from now on.
Flat out Frizz Fighter:
"Daily smoothing cream for fighting frizz and flyaways. Perfect for flat ironing. Moisturizes dry hair and helps improve the appearance of split ends"
"Apply to dry hair any time during the styling process to get and keep control. Use as a finisher to defeat frizz and hold down flyaways."This is my absolute favourite product in the line, in fact, this is my favourite product FULL STOP at the moment. I have always had issues with the top back section of my hair frizzing and ruining the whole do, and this has helped so much! I'm actually scared to run out of this so will be making sure i stay fully stocked up. Again its a lotion/cream form and has the same scent which is signature for this line. Unlike the curling custard, this one says you can use it on dry hair, which means that it can be used every day. It says it is perfect for flat ironing, which i am not going to be doing, but it works perfectly well on curls keeping them frizz free all day. I am honestly in love with this one.
Shea & Coconut Oil:
"Makes dry, unruly hair smooth and manageable, while re-hydrating scale and nourishing roots."
"Apply a small amount to hair and scalp 2-3 times per week. Use as a pre-poo treatment to moisturise and nourish the hair and scalp."I love using oils on my hair for scalp massages, prepoos and as sealants, and this one is great. It is slightly thicker than ones i am used to, and so getting used to how much to use was a challenge. No one wants greasy hair. I have it mastered now and i love this oil. It smells so good. Yes its the same signature smell, but its a little stronger. I use this after i have styled my hair and the use my diffuser to dry it all in. When my hair is about 80% dry i apply a little more of this oil and let it air dry. The results? Super shiny hair!
I LOVE this range. My hair has never looked so great. These photos have NO FILTER on them, just a flash on this one >.
Not only is my hair frizz free, defined and soft, but the shine is incredible.
I cant wait to get my hands on the leave-in conditioner. These two photos here are from a wash and go using all of the products i have reviewed here and nothing else. My hair is 100% dry and usually at that point, my top back section is a mess. These products have completely changed my hair for the better.
They are products that will be on my shelf and draws permanently from now on.
I haven't yet found retailers which stock this in my area, but i have seen it on Amazon. I know that this is the same people who made Soft'n'free which is easily available in most afro hair stores, so i will keep you updated when i find other places you can get it.
If you are in the states, then you can just click directly on the website (i am so jealous of you guys!)
Have you tried this brand yet?
Instagram: candi_curls
Twitter: candi_curls
Facebook: princess candi curls
Youtube: princess candi


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North Central Florida
Aunt Bertha
Allows users to search for local resources by typing in their zip code. It gives a categorized directory of services including emergency, food, housing, goods, transit, health, money, care and education. This online platform is provided by the Partnership for Strong Families.
Community Resource Guide
Includes relevant information on agencies and organizations throughout Alachua, Bradford, Gilchrist, Levy and Putnam counties. Provided by the Alachua County Coalition for the Homeless and Hungry, available in PDF format.
Consumer Resource Guide
Lists agencies throughout Florida, organized by county and provided by the State of Florida Elder Affairs, available in PDF format.
Healthy Start of North Central Florida
Healthy Start services are available to all pregnant women and families with babies up to age 3. Services include education and support in childbirth, breastfeeding, parenting, women's health, tobacco cessation and counseling. Healthy Start of North Central Florida serves 12 counties in the region.
Contact a Healthy Start Care Coordinator in your county.
To find information about Healthy Start in other counties visit Florida Association of Healthy Start.
Read about a range of topics, from signs of labor and C-Sections to infant safety, on the Educational Resources page of the Healthy Start of North Central Florida website.
The Cancer Resource Guide of North Central Florida
A valuable tool for cancer patients, survivors, caregivers and family members. Also helpful for those not directly touched by cancer, this resource includes listings for financial support, tobacco cessation and a range of community resources. The guide covers all counties in North Central Florida. Provided by The North Central Florida Cancer Collaborative and WellFlorida Council.
United Way 211 Community Resource Directory
Allows users to search for resources by zip code, age, gender, key word, agency name or specific program categories. This online search directory is provided by United Way, which primarily serves children and elders. Also available is a 24-hour information and referral helpline: call 2-1-1.
Bradford County
Bradford County Community Resource Guide
Includes services such as: education/employment, food/nutrition, rent/utilities/housing, special needs/disabilities and more. Provided by the Episcopal Children's Services. Available as a PDF.
Career Source Community Resources
A list of resources in Alachua and Bradford counties. Provided by Career Source North Central Florida.
Putnam County
Charities and Social Services Directory
Offers a listing of charities and social services in Putnam County. Provided by Benevolence Support Services of Ocala.
Putnam County Resource Directory:
Lists a wide range of services available in Putnam County from anger management programs to programs for elders. Provided by the United Vision Program, a partnership of CDS Family and Behavioral Health Services, the Juvenile Crime Prevention Office and the Putnam County School District. Available as a downloadable PDF.


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You should prepare yourself with the right information to have your car repaired if it develops a problem. It can be very costly to fix a vehicle, so you should know know the basics about auto repair if you want to be satisfied with the results. This article will guide you through all you need to know about auto repair.
A breakdown can happen at any time, so it is important to have an emergency kit somewhere in your car. Include a spare tire, a jack, a battery charger and a container full of gas. Consider having blankets, batteries and a flashlight for unexpected nighttime break downs.
Ask any questions you have. Find out what caused the issues, and ask what you can do so this does not happen again. Preventing automotive issues is a valuable skill to save money during the year.
Keep an eye on your radiator levels. Keep your car running then shut the engine for several minutes before opening the hood. Never open the radiator on a running car. With a dipstick, check your radiator fluid. Before adding more coolant remember to mix it with water.
Know what the repair is going to cost you before handing over your keys. Have your mechanic or service adviser clarify all the details before agreeing to getting your vehicle fixed. You don't want to be hit with unexpected charges after the repairs are done.
In order to prevent rust to your car, wash it on a regular basis. All cars will eventually rust out, but you can delay the process considerably by making sure any salt or chemicals are washed off as soon as possible. Protect your paint with regular waxing.
There are better ways to deal with car problems and you should be better informed about these ways now. What you have learned here is going to make you a lot more prepared when you end up having to deal with getting auto repairs. Keep these tips in mind when you see a potential problem occurring.
Auto Repair Irvine
Foreign and Domestic Auto Service Shop
Call Today: 949-743-0153 – Fix Your Car Today
AAA Auto Approved with ASE Mechanics


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Get our FREE monthly edition
Create Products
Laptops, Notebooks & PC's
Suppliers of Bluetooth-enabled PC & Laptops.
If you know of
others please
e-mail us details. Thank you.
Apple PowerBook
12" with Bluetooth built in.
Apple PowerBook
17" with Bluetooth built in.
Power Mac G4 tower models
have an internal Bluetooth option
Compaq (merging with HP)
Company website
Founded in
1982, Compaq Computer Corporation
is a global provider of
information technology products,
services and solutions for
enterprise customers.
Bluetooth Pocket PC H3870 is a pocket PC. It's not much bigger than a calculator and
comes standard with applications like Microsoft Pocket Word, Excel, Outlook,
Internet Explorer, and Windows Media Player. It features integrated Bluetooth
technology. Other features include: 206 MHz Intel StrongARM 32-bit RISC
Processor, Color reflective thin film transistor (TFT) LCD, 64K colors, Touch
Screen, Resolution: 240 x 320, 64 MB RAM, 32MB ROM, Handwriting recognition,
soft keyboard, voice record, inking, Interface with USB / Serial connectivity,
SD Memory Slot, Infrared port (115 Kbps), Speaker & Microphone, Operating
System: Microsoft Pocket PC 2002, Dimensions: 5.3" x 3.3" x .62",
Weight: 6.7 oz. including battery
is a family of Bluetooth enabled
laptop computers. It also
implements the BNEP protocol and
supports the PAN profile.
- e-mail
us if you can help with further
- e-mail
us if you can help with further
- e-mail
us if you can help with further
- e-mail
us if you can help with further
Fujitsu Siemens
Company website
A major supplier of PC's - desktops, notebooks and laptops - Fujitsu
Siemens is now offering
Bluetooth technology as part of its PC product range
Fujitsu Siemens Computers offers their LIFEBOOK product range with integrated
BluetoothTM technology as well as accessories such as USB adapters and PC Cards
as soon as they can guarantee interoperability to their customers.
Company Website
Headquartered in Tokyo, Japan,
Hitachi is a large global
electronics company. The company
manufactures and markets a wide
range of products, including
computers, semiconductors,
consumer products and power and
industrial equipment
Personal Computer - e-mail
us if you can help with further
Notebook Personal Computer offers
Bluetooth functionality with the
built-in Bluetooth module. The
Bluetooth module daughter board
contains the integrated Bluetooth
radio, controller circuitry, USB
interface and coaxial cable to the
Bluetooth antenna. - e-mail
us if you can help with further
Intermec Technologies Corp. is best known as the inventor of the world's
most widely used bar code symbology. Intermec today provides supply chain
information products, services and systems to companies in industries around the
The 700 Series
Mobile is a rugged radio-enabled
mobile computer. Based on the
Intel StrongARM processor and
Microsoft Windows for Pocket PC,
it is aimed at applications in
field service, healthcare, retail,
route distribution and logistics.
The 700 Series provides Ethernet
connectivity through its docking
systems. Wireless LAN systems in
retail and distribution center
applications can use the 802.11b
internal radio (Wi-Fi certified).
It has Bluetooth capability also
and allows wireless communications
with peripheral devices such as
NEC Corporation
Company Website
NEC Corporation is a provider of Internet solutions, dedicated to meeting the
specialized needs of its customers in the key computer, network and electron
device fields.
Personal Computer. - further details unavailable, e-mail
if you can help us.
Personal Computer. - further details unavailable, e-mail
if you can help us.
Company Website
Established in 1946, Sony
has been one of the early players
to market with several products
incorporating Bluetooth, including
PCs, laptops and camcorders. Sony
C1VFK Notebook has an integrated motion eye digital camera and
Bluetooth capabilities.
Features: Crusoe processor, 15 GB hard disk drive and 128 MB
SDRAM, Bluetooth
module with 723 kbps connection at a distance of up to 100 metres, Integral
MOTION EYE CCD camera for still photographs and video, Jog Dial delivers
intuitive control of key applications, MagicGate Memory Stick slot for data
storage and electronic music download, Weighs 1 kg.
VAIO SR31K Notebook
Features: Mobile
Intel® Pentium III Processor 750 MHz LV featuring Intel SpeedStep
technology, 15 GB hard disk drive and 128 MB SDRAM, Bluetooth module with 723
kbps connection at a distance of up to 100 metres, Built-in modem, weighs 1.36
kg, Jog Dial delivers intuitive control of key applications, MagicGate Memory
Stick slot for data storage and electronic music download.
Toshiba America Information Systems Inc. has launched
mid-September two notebooks with integrated Bluetooth
capabilities aimed at traveling business users.
The Tecra 9000 series and Portégé 4000 series have both 802.11b and
Bluetooth antennas embedded in the lid of the notebook, eliminating the need for
a PC card. Bluetooth can be used to synchronize to PDAs and
not have to travel with any cables while 802.11b can be used to interwork with
existing wireless LAN installations.
The notebooks also incorporate a Secure Digital (SD) Media slot, so
users can slide a Toshiba SD Memory card directly into the notebook - SD cards
are used in PDAs (personal digital assistants), digital cameras and MP3 players.
A 128M-byte card can store up to four hours of music or 40 minutes of video. In
the future third-party vendors may develop SD cards just like PC Cards today
Tecra 9000 Series
Weight 5.3 pounds (2.4 kilograms), 14-inch (35.5 centimeter) screen, DVD
(digital versatile disc) player. The bay can also use six other Toshiba devices,
including an extra battery, hard drive and a rewriteable CD-ROM drive.
Integrated 10/100 Ethernet port, infrared and an i.Link port. The i.Link
interface, also known as IEEE 1394 and FireWire, is used to connect PCs to
digital audio and video equipment.
Portege 4000 Series
Weight 4.4 pounds, 12-inch display. In the extra bay, the notebook can share the
same components as the Tecra, including an extra hard drive or CD-ROM drive.
Both notebooks can share the same port replicator, which features a
DVI (digital video interface) port and an i.Link port.
Copyright ©
2001-2003 WTIS Ltd, Wireless Telecommunications Information & Services
All rights reserved.
mailto: email@example.com
Bluetooth is a registered trademark owned by the Bluetooth SIG Inc.
All registered servicemarks and trademarks mentioned on this site are
Last modified: Wednesday December 03, 2003.
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text:
Subscribe To Rolling Stones Guitarist Ronnie Wood Is Getting Married Again Updates
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Ronnie Wood is reportedly planning to walk down the aisle. The Rolling Stones guitarist popped the question to girlfriend Sally Humphreys last week, and by all accounts, she said yes. No specific details or arrangements have been made as of yet by the couple who have been inseparable for months, but the basic announcement did reportedly lead Wood's bandmmate Keith Richards to tell his friend he's pissed about having to buy him a third wedding gift.
Thanks to his time with the Rolling Stones and the Faces, Wood's romances and relationship problems have been heavily discussed in the media. He was first married to Krissy Findlay from '71 to 78. A few years later, he took up with Jo Wood, who he was married to until 2008 when he left her for a twenty-four-year-old cocktail waitress. That affair didn't last long, and the lack of attatchment eventually led him to the thirty-four-year-old Humphreys who everyone seems to like.
Here's what Ronnie's stepson Jamie told The Sun…
"Sally's not one of the bimbos he usually goes for. She's exactly what he needs. I don't think he can keep up with bimbos any more."
It's never too late to grow up. At 65, Wood should have a lot of years left in him, and it's worth it to spend that time with someone he actually cares about. There's no guarantee this union will prosper, but judging by the reactions of those around him, it sounds like there's a real chance this could go the distance. Pop Blend sends out its sincerest thoughts to the recently engaged couple as they begin plans to start a life together.


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Scott Blair- Creates Comics on Tampa
Scott Blair, "my comics focuses on vampires and werewolves in Florida" my first two issues of "Gator Balt" uses Tampa as the setting for its story. In addition I have a new project Vamps verses Wolves which follows a similar premise.
I travel all over to sell my comics and prints and in the seven years in this industry I still find it challenging to reach new fans but I love what I do… so I keep on working.
Scott Blair
Website: scottblairart.com
Follow for updates: @scottblairart
Born in South America, Guyana to a Jamaican father, Earl Speid developed a passion for the arts at a very early age and in 2002 he received a BFA from Parsons School of Art and Design in Manhattan, New York. And has since worked as a professional artist drawing inspiration from all different forms of art especially photography.


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Hi everyone
A quick note to let you know I released Veronica Speedwell on Ravelry today.
Thank you all so much for your supportive comments in my first post – I am so glad you like them!
I have always been a little frustrated at the seeming lack of YouTube tutorials that explain how to create colour dominance in stranded knitting. One would have been immensely useful to me when I was working out how to get my motifs to 'pop' against the background fabric when I was learning to knit fair isle/stranded colourwork correctly.
I put these videos together to demonstrate techniques that I describe in my upcoming sock pattern, Veronica Speedwell. The videos were shot in one take, and they are by no means a polished performance, but I think they get the message through, so I am happy enough to post them! Please forgive the verbal fumbling and the plaster in the first video. My finger is suffering from excessive contact with sharp, pointy sticks. 🙂
I don't address holding the yarn in this video. There are many, many YouTube tutorials out there on this subject, so feel free to explore them to find a method you prefer. As you can see, my technique is the simplest – I carry the yarn one colour at a time.
The sock you see in the video is my prototype for another pattern. Don't look too closely now! 😀
On colour dominance and general tips on stranded knitting:
On catching long floats:
Today, for the first time in ages, I woke up without the weight of a deadline hanging over my head. It felt so good.
I decided that with some free time on a rainy day, this would be a good opportunity to make further investigations into some projects that I've been eyeing recently.
But first, let me show you this!
They are done! I love them so much. They're at once very "Alice in Wonderland" and "Wicked Witch of the West" don't you think? I'm looking forward to refreshing my stocks of Happy-go-knitty next Saturday at the Wellington Underground annual "Wonders of Wool" market. More, pretty stripy socks coming my way! Funny how we knitters talk about yarn in terms of a finished project.
Also, another happiness-making thing happened yesterday:
Seven glorious hanks of Knitsch Milky Way, for the knitting of the Southern Companion were ready for my pick-up!
At Holland Road Yarn Company, Tash was busy making final preparations for her stall at this weekend's Creative Fibre Festival. Oh my. Such hanks of gloriousness I saw, to set the heart aflutter! I hope there's still some left when I turn up…
Now to what I did today. This is what one's living room ends up looking like in the middle of a creative frenzy:
What was this all about you ask? I've been eyeing the below interesting cardigan all week:
It's called Conifer (designed by Rosee Woodland), and it's in Issue 54 of The Knitter.
Several features attracted me to it: the knitted-on fingerless gloves (very handy to keep those winds out of one's sleeves) and the fact that it's knitted in reverse stocking stitch. The certain someone I'm knitting it for likes to wear her sweaters inside out because she prefers the smooth feeling of the stocking stitch instead of the purl bumps. This would be perfect! The final feature I liked was the unusual reverse fair isle. I've been thinking about using reverse fair isle in a pattern, and this looked like a good opportunity to try it out.
I also had in mind a certain person's comment about knits in the English town she lives in "Oh, fair isle is so common, everyone wears it, it's not special to me any more." Perhaps an unusual take on fair isle might be good?
I thought that Knitsch would make a perfect medium for it, given it's meant to be for a certain girl who dislikes itch. So, diving into my precious hoard of Knitsch, I did a bit of a stocktake of possibilities:
Something colourful for the yoke perhaps?
However, as I was winding the balls, it occurred to me that while all those colours looked oh-so-pretty together, they might seem cartoonish all in one garment.
I pared it down to pretty purple shades with a touch of gold:
I'm not sure about that gold, but the purples looked good. The only downside was that when I measured the swatch, the gauge was far too small. Bother and horrors. That swatch was a real brain-teaser to knit too! Reverse fair isle is tricky until you figure out that you can't knit it like normal fair isle!!
I sat there feeling annoyed. Knitsch was very much what I wanted to use. I didn't really fancy knitting more swatches until I found a yarn that matched. Besides, I don't have any other yarn in my stash with that colour range. Why didn't it match? They were both 4 ply after all!? They felt the same thickness in the hand. I decided that I would see how many wraps per inch the J&S was… 15 per inch. Then I wrapped the Knitsch, I found that it's more like 20 wraps per inch! Ah. It made sense now. I should probably have done that first. Doh.
I wondered how Zealana Kiwi Fingering would work out. She likes that yarn too. I wrapped it, and found that it is exactly 15 wraps per inch! I was surprised, because Kiwi feels a lot thicker. (J&S is springier and lighter, but the width of the strand is the same). So… although I don't have a large colour range in that yarn, I decided to do one more swatch to see if really was the right match:
I am pleased to say that it gives the exact gauge that I need for this pattern.
My concentration petered out in the final row and I messed up the swatch. The young boy got bored and started to watch a video. And with the invasion of irritating noise into the ears came the advent of a headache and the loss of all ability to concentrate. I need a nice, quiet, cosy little cabin at the end of the garden in which to knit, far from loud, concentration-shattering noises…
So now I need to go shopping for colours. But I guess I should consult with a certain girl first to see what she'd like? 🙂
I've had this Jamieson & Smith 2 ply jumper weight yarn in my stash for quite a long time. Waiting for the right project. I've blogged about it before when I thought I might have found the right thing for it. I think I've finally (!?) found it.
For quite some time I have also been searching for a fair isle project that I'd love to wear. That, combined with the classic feel and look of a traditional yarn like the Jamieson & Smith yarn merged into the perfect combination recently: Trefoil.
It has the perfect amount of fair isle – just around the yoke – so that I don't get bored of all that stranding, and it's a lovely design.
I started swatching before Christmas.
After I'd finished, I wasn't sure if it was right. The middle section looked murky. You can't really see the flower pattern. Frustratingly, I didn't really have any other colours in my stash that were any better. I didn't really have anything similarly textured and shaded (ie tweed or heathered) to match nicely with it.
In the meantime, I had an interesting conversation with my daughter:
"Mother, you know that nice green cardigan you knitted in Heron for me?"
"Yes. Why?"
"Well, people think it looks very nice on me. And this colour you're knitting here looks just like that colour, and I think that perhaps you need to knit that cardigan for me!" (accompanied by puppy eyes)
Thinking fast…(damn, I want this cardigan!) "It's itchy wool. You won't like it."
Rapid fire response… "Well, how about knitting me one in Knitsch?"
One taken aback and slightly impressed mother at how quickly her daughter can counter-attack in knitting terms (quick thinking on her part to think of fingering weight yarn with all the right colours I can choose from and that isn't itchy!): "Hmm. I suppose I could do that."
So now it looks like I'll have to knit two of these. One for her, and one for me!
The project swatch then sat in my 'think about' basket for a couple of months. If only I had more of that lovely Rowan Fine Tweed to play with!
Recently, I had the good fortune to engage in another happy yarn swap with Colette, and this is what I got:
Hurrah! Thank you Colette!
I started swatching…
Better, but still not right.
Much cursing and huffing later…
Ah, this one felt just right. It gave me that happy "twang" in the belly when I saw it finished. Do you get that when you know something's just right?
The colours tone with each other perfectly. I'm not sure if you can see it in the picture, but Askrigg, the deep blue, contains the same green and red flecks that are in both Wensley (the blue/green) and Settle (the plum). Buckden forms the neutral background, and I repeated the J&S colour (FC62) through the centre. They tie in perfectly. Magic!
I finally remembered that fair isle colours work best if the colours are the same tone. Silly me.
Let the knitting begin!
I don't know if it is correct to call something "heartbreakingly lovely". But in my opinion, this wee cardigan for my niece fits the bill. I'm so, so happy with it!
I don't know why it took me so long to gear up and knit the final sleeve. Perhaps I just didn't want the project to end? It's the colours that I'm particularly happy with. The combination of honey, cream, greens and pinks are so fortuitously harmonious.
Even though I saved myself a lot of trouble by knitting this in one piece up to the armholes (as opposed to separate pieces), the millions of ends I still ended up with took a couple of evenings to sew in. Looking at this picture still makes me feel a little stressed…there.were.so.many!!!! I have now decided that steeking is an excellent idea, and I shall be trying that out for my next colourwork project!
I decided to forgo buttonholes, and used snaps instead, reinforced with 'fake' buttons and some pretty pink ribbon, to make it look 'finished' and give the bands strength.
This cardigan is such a pretty combination of pure wool from around the world. There's a bit of Jamieson & Smith Shetland jumper weight in 2 ply (greens), a bit of Rowan Scottish Tweed 4 ply (pink – thanks Kb!), and some Australian eco merino (brand no longer available) in cream and honey. The pattern is from Debbie Bliss' book Special Family Knits. It's the Fair Isle Cardigan. Click here for my Ravelry notes if you'd like more details (I will post more photos to that page, but there's an issue with loading photos to Ravelry at the moment for some reason).
I can't wait to see my littlest niece in this one.
I have a small confession.
I was going great guns on the cardigan. The body is done and one sleeve almost finished. But somewhere along the line, my interest waned… I blame the socks.
They were, um, slightly addictive.
I used a German yarn this time – ONline Supersocke 100. 2.25mm needles. It's a lovely colour, but I'm not sure I'll use the yarn again. I found it quite splitty to work with (obviously, this did not stop my enthusiasm for knitting the sock though…!)
To make myself feel better about not finishing my niece's cardigan yet I went looking for, and found, all the items of haberdashery I need to finish the cardi (a little bit of pretty ribbon and some buttons). I figure I'll pick up the needles again tonight.
I have also cast on for this (Gemma). It has taken me a while to find the pattern I wanted to knit, but I found it today! Do you ever have a picture in your head of the thing you know will suit someone and then it's really hard to find that exact pattern? That was me, looking for Gemma. So happy that Hilary Smith Callis came up with the pattern I wanted!
I'm going to knit it in this:
This is Little Wool Co.'s pure wool in DK. The colour is Damson.
Hope to have something pretty to show you soon.


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The PC Detective Pro ver. 2.8.8
The PC Detective PRO is a powerful PC spy utility that monitors your PC or multiple PCls over a network logging all activity including websites visited, applications run, all keystrokes, chat conversations, Instant messages and regular screen captures all in complete stealth, so users will be unaware of it presence, enabling you to keep track on what your kids, spouse, employees etc are up to on your PCls while you are away.
Key Features:
• Websites visited.
• Applications run.
• View Current Apps & Websites.
• Keystrokes.
• Chat conversations.
• Instant messages.
• Regular screen captures.
• Built in Popup Blocker.
• Application Blocker.
• Website Blocker.
• Runs in complete stealth.
• View other desktop screens in real time over a network.
• Monitor up to four desktop screens simultaneously over a network
• Send log reports via email


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Gauging The Cost of Your Kitchen or Bath Remodeling Project and Why
It is always nice to picture how much better a room will look once you give it a makeover. However, when you go for your kitchen or bathroom makeover, you should always evaluate the ROI (return on investment) or as some prefer to put it – cost vs. value.
Before you lay out your hard-earned cash you need to evaluate whether or not this remodeling project will add real value to your home. A lot of homeowners just know they want it done but haven't a clue as to whether or not it is a good investment. Not all remodeling projects will bring in the same benefits but it's good to have a handle on what the pluses and minuses are before you begin.
The two rooms that carry the most significant benefits are the Kitchen and the Bathroom. When these are updated they usually bring a substantial ROI. This is especially true if you are going to sell your home.
The experts from Phoenix bathroom remodeling agree that remodeling the kitchen is on the top of the list for those who are planning to sell their homes. The reason for this is because most people overestimate the costs of updating it themselves. When they walk into an older kitchen all they see are additional costs pushing them over and above the price of closing on the home. They see huge dollars floating away from them.
Phoenix Bathroom and Kitchen Remodeling Specialists:
Overall, a minor kitchen remodeling project can bring back as much as 82.7% or the cost of your project to your home value.
One fact rings true regardless of what room your remodeling project will be aimed at – 'it's very important to perform the right remodel'. You don't want to add an ultramodern kitchen to a 90-year old home. That's the wrong type of home improvement if you expect to get a good ROI.
Preconstruction Planning
Planning – The planning of your kitchen should actually take longer than its actual construction. Planning well will save construction time because it eliminates a lot of unexpected setbacks. It also helps you to stay on budget.
Six months of planning is the recommended time as stated by 'The National Kitchen & Bath Association'. This keeps you from always changing your mind while construction is going on and adding costs to your project. So Plan, Plan, Plan, and then go and plan some more.
While you're planning, keep these things in mind:
- Traffic Patterns
- Ergonomic Designs
- Anything Possibly Unforeseen (expect the unexpected)
- Nail Down What Fixtures and Materials You'll be Using Prior to Beginning


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To John Adams from Thomas Jefferson, 20 January 1791
Philadelphia Jan. 20. 1791.
I have the honor to inclose you a letter from one of our captive citizens of Algiers, if I may judge from the superscription and from the letters from the same quarter which I have received myself. as these relate to a matter before your house, and contain some information we have not before had, I take the liberty of inclosing you copies of them.
I have the honour to be with sentiments of the most profound respect & attachment, Sir / Your most obedient / & most humble servt.
Th: Jefferson
DLC: Papers of Thomas Jefferson.


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By Ryan Maquiñana
As Robert "The Ghost" Guerrero commenced his Big Bear training camp for the fight of his life August 27 against Marcos Maidana in San Jose, the three-division beltholder took time out to speak to BoxingScene.
"I got here last Sunday, and I've been here a good week and a half now," he shared, preparing for his shot at the WBA junior welterweight 'regular' title. "Monday was the first day of sparring. I went four rounds with Frankie Gomez. Abel [Sanchez]'s also bringing in a 140-pound Russian guy to spar me."
While it always feels good to get back in the ring, one must never neglect the seemingly peripheral aspects of training as well. At Big Bear, the lofty heights above sea level can leave a fighter gasping for air in the early stage of roadwork. The mountainous terrain offers quite the contrast to his last camp in Las Vegas or his usual locale of Gilroy, Calif., his hometown.
"It's definitely different from Gilroy," he stated without hesitation. "Training at 7,000 feet, it's a tougher run because there's not that much oxygen in the air. It's harder to breathe. Once you get used to the elevation, you can do what you usually do, like run four to five miles. That first week you're breaking in, but you have to know when to push and when to pull, so there's a fine line so you don't get overworked."
Guerrero insists that he's been mindful of all parts of his training.
"All last week it was about getting acclimated to the elevation and doing my runs," he recalled. "I've been doing a lot of shadowboxing, working mitts, bag work, you know, the basic stuff. I've been keeping it real light to get accustomed to the elevation, but everything's on pace."
Pacing has become the word of the day for Team Guerrero, right down to his eventual battle with the scale.
"Right now I'm about 147 pounds," he said, which is seven pounds over the junior welterweight limit. "I'm right where I need to be. By fight night I'll be 140. I'm feeling good, feeling strong. Like I said, everything's right on pace where it needs to be."
The preparation doesn't stop when "The Ghost" unwinds back in his room. Ruben Guerrero Sr., his father and trainer, soon arrives with manager Bob Santos with the DVD player with what probably won't be a bootleg copy of Horrible Bosses or Captain America.
"We're always watching film, studying Maidana," he said. "You have to be a student of the game and break the fighter down. We watch him over and over to get his rhythm and movement ingrained into your mind. We're working on strategy and the gameplan now."
One of those broadcasts is the bout that put Maidana on the map, the relentless upset stoppage of Victor Ortiz, who like Guerrero is a southpaw. When asked if he'd be paying more attention to that disc in the collection because of the similarity in styles, Guerrero answered in kind:
"Well, Maidana comes to fight. He is what he is and he knows what he is no matter what style he's fighting against. He's coming to take you out. He's one of those fighters that you have to be careful of because he changes his pace and he catches you sleeping. He's very unorthodox."
Maidana will be defending an interim belt that will be elevated to a "regular" belt due to WBA regulations concerning unification bouts. It just so happens that the Argentine's last loss was to the man who will fight on Saturday for the "super" version of the belt, Amir Khan.
Of course, if Guerrero beats Maidana, he might very well be in line to face the winner. So will Team Guerrero glue their eyeballs to the screen this weekend?
"I'll be watching the fight, but our main focus is Marcos Maidana," he admitted. "I have to get past him first. I'm pretty sure this fight right here is an eliminator to fight the winner, so it's exciting, but you still have to take care of business come fight night."
The "Ghost" did put his analyst's hat on for a moment and broke down the matchup between Khan and IBF champ Zab Judah.
"Especially with a lefty with punching power and handspeed like Zab, I would like to see how he reacts to him, because I'm a southpaw, too," he said. "Zab's got skills and experience. Also, he has [Pernell] Whitaker working with him who in his day was one of the craftiest fighters, and to this day, is one of the best lefties ever."
He ended his thoughts with a prediction.
"With the Amir Khan and Zab Judah fight, to me it's a pick 'em fight," he opined. "It can go either way. I'm hoping to see a good fight between the two, because the better it is for me when I step up to the plate. If I really have to make a prediction, though, I think Amir Khan beats Judah by a split decision."
Guerrero was much less definite when asked to call his own fight.
"I really don't like giving predictions on my own fights except that I'm coming to win and I'll be ready in top shape," he promised. "I've giving myself the opportunity to win being here in Big Bear training hard."
With his wife Casey and their children back home in Gilroy, Guerrero vows to leave nothing to chance in the days leading up to August 27.
"I've been talking to them over the phone to see how everything's going," he said. "My family and the whole Bay Area's excited for the fight, and now I just have to stay focused."
Ryan Maquiñana is the boxing correspondent at Comcast SportsNet Bay Area and a member of the Boxing Writers Association of America. E-mail him at [email protected], contact him on Facebook or follow him on Twitter: @RMaq28.


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ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at firstname.lastname@example.com.
- 1 English
- Mechanical engineering
- Artificial Fingers
- Haptic Exploration
- 1 Biomedical engineering
- 1 Multimodal Tactile Sensing
- 1 Prosthetic Hands
- 1 Robotic Hands
- more
- 1 Robotics
- 1 Slip Detection
- Dwarf Galaxies as Laboratories of Protogalaxy Physics: Canonical Star Formation Laws at Low Metallicity
- Evolutionary Genetics of CORL Proteins
- Social Skills and Executive Functioning in Children with PCDH-19
- Deep Domain Fusion for Adaptive Image Classification
- Software Defined Pulse-Doppler Radar for Over-The-Air Applications: The Joint Radar-Communications Experiment
Effective tactile sensing in prosthetic and robotic hands is crucial for improving the functionality of such hands and enhancing the user's experience. Thus, improving the range of tactile sensing capabilities is essential for developing versatile artificial hands. Multimodal tactile sensors called BioTacs, which include a hydrophone and a force electrode array, were used to understand how grip force, contact angle, object texture, and slip direction may be encoded in the sensor data. Findings show that slip induced under conditions of high contact angles and grip forces resulted in significant changes in both AC and DC pressure magnitude and rate of …
- Contributors
- Hsia, Albert, Santos, Veronica J, Santello, Marco, et al.
- Created Date
- 2012


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How Nairobi shaped future president
Friday April 13 2012
When 26-year-old Joyce Banda boarded a plane to Nairobi in 1975, she did not know that she was embarking on a journey that would not only see her leave her abusive marriage, but also bring her to the highest office in the land, albeit three and half decades later.
Ms Banda became Malawi's president last week following the death of Mr Bingu wa Mutharika, who had led the southern African country since 2004.
Acquiescent and dutiful, the mother of three had flown to join her husband Geoffrey Kachale, who was working at the Malawian embassy in Kenya.
"I think it all started out when I went to live in Kenya, because that is the time they declared the decade for women, 1975. I didn't realise at that time that I was locked up in an abusive marriage. As an African woman, I had been brought up to believe that, that was normal, that if you are in a marriage there is nothing too much for you to bear, you can tolerate anything, you can live with anything, until I went to Kenya," she told the Harvard Gazette in March last year.
Her sojourn in Kenya coincided with the golden era of renowned women empowerment crusaders led by Mrs Jane Kiano, Prof Miriam Were, Dr Julia Ojiambo, Ms Nyiva Mwendwa and Ms Wilkista Onsando.
The African Women and Child Feature Service executive director, Ms Rosemary Okello-Orlale, interacted with Ms Banda at many forums on gender equality.
Ms Okello-Orlale described Ms Banda as a forthright, firm, principled and dedicated woman.
She praised Ms Banda for refusing to stand down in favour of Mr Mutharika's brother.
"Despite her firmness, she is a motherly and cordial person who is at home with everybody. She always credited Kenya for being a part of her life," Ms Okello-Orlale told the Saturday Nation.
"I just thank God because I was at the right place at the right time… for the first time in my life, I began to hear words like violence against women, abuse, women in development, gender-based violence, gender equality. I didn't even know as an African woman you could begin to think about being equal to anybody," Ms Banda said.
The stage for her as a woman activist and politician was set in 1981, following the end of her husband's diplomatic stint in Nairobi.
On returning to Malawi, and with her newly-minted courage, she left her husband, started a garment manufacturing business and later found Malawi's National Association of Business Women (NABW).
Her visit to the United States further fuelled the fire that had been ignited in Nairobi.
She was inspired by an American women's business organisation to start a small group of women to push the government for equal business opportunities in Malawi.
However, the small group turned into a big organisation. Today, NABW assists more than 20,000 women to set up businesses.
"By the time I went back home, I had made up my mind that the way I was going to reach out was to get maybe 100 women together, form a network, act as a pressure group to push the government for equal opportunity in business. I didn't have the slightest idea that what I was starting was going to be a revolution," said Ms Banda, who is also the patron of the Joyce Banda Foundation, a charity that assists disadvantaged children through education.
Ms Banda earned the nickname, mandasi seller because of her quest to empower small-scale business women.
Ms Banda went into active politics in 1999, winning a parliamentary seat under the former ruling United Democratic Front party ticket.
Once in, she held a number of Cabinet posts under both presidents Bakili Muluzi and Mutharika.
From there, her journey to the top, becoming the country's first female vice-president three years ago, could not be stopped.
Not even a sack from the ruling party by Mr Mutharika could succeed in dimming Ms Banda's star. She had refused to endorse Mutharika's brother as the preferred candidate to succeed in 2014.


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Hey dudes. It's been a while since I've been around because work has been unusually busy (yay? i'm self-employed!) but SmallBeaver is being... uh, not-great* these days and I could use some inspiration from your delightful offspring to get me through tomorrow.
*a term i use in place of all sorts of things I should never call my child.


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Monday, August 12, 2013
Make Up For Ever Full Cover Concealer Review
26 comments:
Hey, we have nominated/tagged you for the liebster award because we love your blog. You can find out rules etc here, but obviously you don't have to do it but it is a fun thing to do! http://lanarosabeauty.blogspot.co.uk/2013/08/leibster-award_12.html#moreReplyDelete
Love and kisses from Laura and Rona x
Eeek! Thank you so much! I'll do the post later today!! (:Delete
This looks really good, I've always used Collection Lasting Perfection Concealer like every other person I'm sure!ReplyDelete
Jenny x
Freya's Fashion ChapterReplies
I've never tried that haha but I think I've heard good things about it! Where do you get it at?Delete
Thanks for this post. Love your blog, keep it up!ReplyDelete
Thanks! (: I'll check yours out!Delete
yay!! You finally got it! There's also a drugstore dupe by Physician's Formula if you want to try it!ReplyDeleteReplies
Ooo I should. I was so desperate that day so I just bought it at Sephora hahaDelete
That's amazing!ReplyDelete
Cute blog :)
Thanks for stopping by mine as well!
-Katie Citizen ImagesReplies
Thanks! (:Delete
And no problem!
Great review - loved that you showed before and after pictures!<3ReplyDelete
http://lameyy.blogspot.co.uk/ <-- please check out our blog xxReplies
Thanks! (:Delete
Love your blog! I followed!
love it! great reviewReplyDelete
btw loved the pictures, you're gorgeous
do you know if they sell this in the states?
Aw thank you! (:Delete
Yeah I live in the states and got it at Sephora (: I think they're having double points this week as well if you have a Beauty Insider card! Haha I got an email about it but I don't know if it's online only or not.
I would absolutely love to try this, it looks like an amazing concealer... I wish we had MUFE here in the UK xxxReplyDelete
Gemma | ♥ Miss Makeup Magpie ♥Replies
Yeah it has definitely turned out to be my favorite! Aw that's too bad :/Delete
Great review! I'm always struggling with dark circles! DXReplyDelete
Ps I followed you! would be great if you could follow back:3 xxReplies
Thanks! (: Yeah, they are so annoying to try and cover up! Haha I wish they just had a miracle cream that completely got rid of them.Delete
Nice blog - followed back! (:
Wow. I need to try this! I have been using Bobbi Brown for a long time now. Although I love it I need to branch out and try something new.ReplyDelete
Hope you'll get a chance and check out my blog. It's all beauty, life and DIY. If you ever have a fun Look/outfit of the day, or a fashion related DIY be sure to share at my "That's my Style" Link party on Fridays! :)
Karla @ www.MySerendipitousLife.comReplies
Yeah I've heard great things about Bobbi Brown!Delete
Love the review, I really want to try it now!ReplyDelete
Life and LoveReplies
Thanks! Yeah it's a great product!Delete
Hi I've nominated you for The Liebster Award!ReplyDelete
Hope you can answer the questions x
Thank you so much!! Yes I definitely will, I don't know why it took me so long to see this comment haha! (:Delete
I wish we had make-up forever products in England! This sounds like a fab product! xoReplyDelete
Check out my Michael Kors Giveaway here!Replies
Aw, yeah that's too bad!Delete


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NOMINEES FOR KBA BOARD OF GOVERNORS ELECTION – three new faces!!!
There may be three new faces on the KBA Board of Governors next year.
John David Meyer of Owensboro replaces a sitting Board Member. In Louisville Douglas Farnsley did not run for re-election. His seat drew two nominees. Ann Oldfather was nominated and is the better known than her opponent Amy Cubbage.
In Northern Ky. challenger Larry Hicks will face off against Board Member Stephan Smith. Smith is employed by a large Cincinnati Law Firm and is not well known outside of Kenton County. Hicks is a popular attorney from a small law firm in Edgewood, Ky.
Section 4 (c) of the Bylaws of the KBA provides all nominating petitions for candidates for the Board of Governors shall be received by the Executive Director at the Kentucky Bar Center prior to 5 p.m. on the last regular business day of the month of October. If only one candidate is nominated in a Supreme Court District, he or she shall be declared elected to that office and the Executive Director shall at once so certify to the Board and the candidate. The election of the following KBA members to the Board of Governors was certified November 1 for a two-year term beginning on July 1, 2013:
1st Supreme Court District Michael Pitman, Murray
2nd Supreme Court District John David Meyer, Owensboro
3rd Supreme Court District Howard O. Mann, Corbin
5th Supreme Court District William R. Garmer, Lexington
7th Supreme Court District Earl M. "Mickey†McGuire, Prestonsburg
Pursuant to Section 9 of the Bylaws, elections will be conducted in the following Supreme Court Districts with candidates for election listed alphabetically:
4th Supreme Court District Amy D. Cubbage, Louisville
Ann B. Oldfather, Louisville
6th Supreme Court District T. Lawrence Hicks, Edgewood
J. Stephen Smith, Fort Mitchell
Ballots will be mailed December 15 to each KBA member in good standing entitled to vote in that election and must be received by the Clerk of the Supreme Court of Kentucky no later than January 15.


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January: Federal court affirms the Supreme Court, finds that the pledge violates free speech whether applied to plaintiffs foreign or domestic affiliates.
April: Oral arguments before the Supreme Court.
January: Supreme Court agrees to hear the case.
July: Government appeals decision to Supreme Court.
February: Second Circuit denies request for rehearing en banc.
September: Government requests rehearing en banc.
July: Second Circuit issues decision affirming preliminary injunction.
December: Oral argument is held at Second Circuit.
May: Government files revised brief at Second Circuit.
April: Government issues final amended regulation and guidelines.
January: Government reinstates appeal at Second Circuit.
November: Government again invites public comment on proposed guidelines.
July: Parties agree to withdrawal of government's appeal, and its reinstatement by January 8, 2010.
June: Government notifies plaintiffs that it wants to issue a new set of revised regulations and withdraw its appeal in the interim.
December: HHS and USAID issue revised regulations related to Policy Requirment.
October: Government again appeals to Second Circuit.
August: District court extends preliminary injunction, barring enforcement of the pledge requirement, to Global Health Council, InterAction, and their members.
April: Government invites public comment on guidelines.
February: Global Health Council and InterAction join case.
November: Second Circuit remands case to district court to consider impact of guidelines and keeps preliminary injunction in place.
August: Second Circuit orders letter briefing on the impact of guidelines on the appeal.
July: HHS and USAID each issue first set of regulations related to Policy Requirement.
June: United States Court of Appeals for the Second Circuit Court hears argument on the appeal. At the argument, Government announces that it will issue guidelines clarifying pledge requirement.
August: Government appeals the ruling.
June: District court issues preliminary injunction barring enforcement of the pledge requirement against AOSI and Pathfinder International.
May: District court rules pledge requirement likely violates First Amendment rights.
December: Pathfinder International joins case.
September: Alliance for Open Society International files challenge to the pledge requirement.
June: The Government starts enforcing the pledge requirement against U.S. organizations. It had previously refrained from doing so based on an opinion by the Department of Justice's Office of Legal Counsel that application to U.S.-based organizations would be unconstitutional.
May: President Bush signs the United States Leadership Against HIV/AIDS, Tuberculosis, and Malaria Act.


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HHHJuly 10th, 2010 at 11:15 am
Hazy, hot and humid. Even the AC isn't cutting it! We have one in our bedroom so we can sleep at night, but it's hard to sleep when you are lying in a pool of sweat! At least it's breaking this weekend and we'll get some badly needed rain as well as some less humid weather to follow.
I was able to visit my veggie garden a few evenings ago. I haven't really been near it since I planted it! How neglectful! I mananged to pull out a lot of weeds, and my 10 tomato plants are thriving. I'm so happy especially since last year there wasn't a decent tomato plant in the state. I have some green beans (well the plants) growing well, and 4 big mounds with zucchini, butternut squash, spaghetti squash and something else! I can't remember what the other one was that I planted, nor can I remember what I planted where. This should be fun! One of the plants has some large flower buds on it, so I'll have to keep my eyes open. I think it's the zucchini, and I don't want the veggies to be the size of baseball bats, so I'll have to be on top of it. I had some herbs not grow, so I'm going to put in a few more rows of green beans. We love them, and I'll can them up. I can the tomatoes too.
The IRS payback will start in August - $200 a month. Originally we were paying $280 a month, but I was concerned about having too much being committed. We have 5 years to pay off the balance, and with $200 a month it'll be less than that. Once our savings gets a little more plentiful, we'll start throwing more cash at this debt.
The other debt I'm starting to pay back is Parent Loan 2. Only $100 a month, but I'll feel better about it as I don't like owing family money. I feel great that we're now able to pay on all of our debts, and not just a few. Those numbers will be dropping and I like it! My mortgage has dropped to $11[u]0[u],710.75...the zero is nice and I was thrilled to see that on our statement. I showed dh - he was less excited than me, only because he's a glass half empty guy and paid more attention to the fact that we still owe well over $100K on it.
We also received dh's gas reimbursement check - that goes right to savings. He's really doing better about spending. He said he was just caught up in the moment, which I understand, but I'm still going to be monitoring him and his bank account to make sure he doesn't go all spendy on me again!
Enjoy the week, everyone!


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Day 2 of 7 of our Get Healthier Campaign
Dinner time - Creamy Butternut Soup
Building on lunch and using the remains of our pre-prepared butternut, we finished off today with a delicious, creamy butternut soup for dinner.
Not just any butternut soup mind you, it's creamy yet dairy free as we added coconut milk to give it a slightly different flavour. But we did not stop there- there is always room for greens, the most neglected veggie group yet one of the most nutritious. A handful of spinach and a sprinkling of seeds for a little crunch finished the dish off perfectly. Plus, it gave it some extra colour.
Creamy Butternut Soup
(Serves 2)To start you will need:
- 1 large butternut
- 3 cloves of garlic
- 1 large onion
- half a cup coconut milk
- handful of spinach
- 1/4 tsp cumin and black pepper to taste
- Extra virgin olive oil to taste
- mixed seeds for topping
- Wash, prick and bake butternut for 45min -1 hour or until soft at 180 degrees.
- Halve the onion and place on a baking tray with the peeled garlic cloves. Add to oven half way through cooking the butternut. Dry roast for 20 min.
- Remove from oven and let cool as it's easier to handle. ( we often bake this the night before when making a separate meal and leave to cool over night).
- Cut butternut in half and remove seeds. Peel off skin and put butternut in a blender.
- Add the onion, garlic and coconut milk.
- Blend on high. Add a little water if too thick.
- Heat in pot for 4-5 minutes adding the remaining spices, stirring occasionally.
- Remove from heat and serve, garnishing with the fresh spinach leaves and seeds and a dash of olive oil. If you like things a little spicy a sprinkle of chili is a nice extra variation.
We would love to hear your feedback so let us know if you try this what you think in the comments below.


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The Demonic King Chases His Wife: The Rebellious Good-for-Nothing Miss Chapter 1232
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Chapter 1232 – Big operation of excavating the tree (4)
This was Central Palace's forbidden area, before, she didn't make a sound, therefore, she didn't alarm the strong experts guarding here, but just now, this sound got out——
Thinking of this, Su Luo's heart immediately went cold.
If she retreated now, she could teleport, naturally could escape unscathed. But like this, wouldn't it be failing through lack of a final effort?
Su Luo wasn't willing ah.
Thus, the Cheng Ying Sword in her hands danced quickly in the breeze, practically displayed to its peak.
Quickly, quickly, quickly!!!
She must take advantage of the time while those strong experts approached to dig out this Divine Spirit Tree!
Su Luo held her breath with rapt attention, all of the spirit force in her body was concentrated into the Cheng Ying Sword.
However, it was very obvious, it was already too late.
The speed of those strong experts approaching was extremely fast.
"Four strong experts at the ninth rank." The little stone proudly reported to Su Luo, "Girl, there isn't enough time, why haven't you quickly withdrawn already?"
Su Luo's heart was unwilling, she didn't even raise her eyes.
If she left today, then Central Palace would absolutely raise the protection around the Divine Spirit Tree to another level. Afterwards, if she wanted to come again to dig out this Divine Spirit Tree, it would be even more difficult.
"There's still a kilometer." The small stone reported in Su Luo's mind.
Because Su Luo focused all her energy on digging, the cold sweat tumbled down drop by drop from her forehead. However, she didn't seem to be aware of it, still as before, mechanically focusing on the movements of her hands.
Four-fifths of the root system had already been dug out, there was still the final little bit…… Only a little bit more……
"There are still five hundred meters left." The little stone's voice carried a trace of precaution, "You can't beat those people, at that time when they lay out the trap, even if you can teleport, you still won't be able to escape."
The little stone's words weren't just used to scare her, rather, they were facts.
Su Luo's eyes unblinkingly stared at that sparkling and translucent snow-white root system, the movements of her hands were so quick as to only leave after-images.
"Still another two hundred meters……" The little stone said indifferently.
"There's not enough time." A thread of helplessness and disappointment flashed through Su Luo's eyes.
Strived for so long, she still had to give up? If she gave up this time, in the future, it would be even more difficult to get this Divine Spirit Tree……Su Luo had an intense unwillingness in her heart.
Just when Su Luo was depressed, suddenly, a thick golden vine flew out of Su Luo's sleeve. The long vine directly wrapped around the middle of the Divine Spirit Tree's body, with a thunderous noise, the entire Divine Spirit Tree was pulled up by the roots!
The Variant Red Acacia Tree! It was the Variant Red Acacia Tree!
Su Luo's heart was immediately elated, didn't expect that at the critical moment, the Spirit Gathering Tree rushed out to help her greatly. Compared to the lazy little stone that could only harp on matters, the Variant Red Acacia Tree was a lot more lovable.
At this moment, endless power from heaven and earth, the intense powerful pressure of strong experts rolled towards Su Luo, pressing her down.
If she didn't go now, then when would she wait until?
Su Luo put away the Divine Spirit Tree and the Variant Red Acacia Tree into her s.p.a.ce, then she concentrated her spirit power and softly mouthed the word: "Teleport!"
Afterwards, Su Luo's figure directly disappeared in place.
Because now was the darkest moment before dawn, the visibility of people's eyes were very low. Separated by a distance of two hundred meters, those strong experts simply didn't notice the existence of Su Luo, this person's shadow.
After they came rus.h.i.+ng over, Su Luo had already taken the Divine Spirit Tree and disappeared long ago.
From front and back, only differed by a breath's time.
"The Divine Spirit Tree!!!!!"
These strong experts at the ninth rank immediately exploded with a violent shout!
The transparent protective screen protecting the Divine Spirit Tree had actually disappeared completely. The area where the Divine Spirit Tree was originally planted, now, apart from a huge mud pit, there wasn't anything else.
The Divine Spirit Tree!
Central Palace's treasure within the Zhen Palace, actually disappeared without a trace, just like this?
The Demonic King Chases His Wife: The Rebellious Good-for-Nothing Miss Chapter 1232
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The Demonic King Chases His Wife: The Rebellious Good-for-Nothing Miss Chapter 1232 summary
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Benjamin Gibbard has shared his cover of Teenage Fanclub's classic 'The Concept'.
The American artist recorded a full version of Teenage Fanclub's 'Bandwagonesque' earlier this year, set to be given a general release through Canvasback Music / Turntable Kitchen.
Turntable Kitchen will provide a limited vinyl release, which will come with a bonus seven inch version of 'The Concept'.
A tender, admirably straight cover version, the seven inch version of 'The Concept' will also feature recordings of Alex Chilton's 'Free Again and Beat Happenings' 'Bad Seeds', both of which were covered by Teenage Fanclub themselves.
Benjamin explains: "'Bandwagonesque' is my favourite record by my favourite band of all time. It came along at a pivotal time in my musical life and I've loved it for over 25 years. It's been such a blast taking these songs apart to see how they work and then putting them back together again".
Check out 'The Concept' below.
Benjamin Gibbard's version of 'Bandwagonesque' will be released on July 28th.
For tickets to the latest Death Cab For Cutie shows click HERE.


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Shack PSA: Free Bruce Springsteen Guitar Hero DLC Will Cost Money Next Week
If you're interested in these, make sure to act fast, as the tracks are only free for one week. Come next Tuesday, February 5, the Xbox 360 and PlayStation 3 tunes will only be available in $3.99 bundle, while Wii owners will have to buy each track for $2.
By the way, the Xbox Live Marketplace currently lists the free Xbox 360 tracks as only available to those that bought or redeemed an Xbox Live Gold membership. Since items are generally Gold-exclusive for a week, it looks Silver-level users will have to pay, one way or another, if they want to play The Boss in Guitar Hero World Tour on Xbox 360.
From The Chatty


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Refine your search for walks in Somerset
The walk follows the Corton Ridge and offers great views across the Somerset Levels and the Dorset Hills. It has great historic significance as Cadbury Castle is reputed to be Camelot King Arthur's Castle. You also cross the ancient medieval village of Whitcombe. It's an up and downer and can be boggy in wet weather. As an incentive there are two great pubs you can call in at!
Selworthy Beacon and North Hill are the main objectives of this walk from Bossington, Somerset. The route offers a variety of Exmoor scenery with coastal hills, views of high moors and the interesting village of Selworthy.
Walk through Rowberrow Warren which is a beautiful woodland, set on a hillside with large paths.
This walk in the Quantock Hills takes you to Wills Neck the highest point in this Area of Outsanding Natural Beauty. There is a sharp climb to start before you start to enjoy the extensive views.
A short easy stroll to the highest point of the Quantock Hills. Do choose a day with good visibility as the views in all directions are extensive.
This Somerset walk in the Quantock Hills provides some wonderful views of this beautiful part of Britain. The route follows well trodden paths and tracks for most the way. Choose a day with good visibility to make the most of this scenic walk.
This Exmoor walk starts from Tarr Steps, a well-known beauty spot, and then continues through countryside of steep, green fields dotted with small farms. The route crosses West Ansley Common before returning to the start through the village of Hawkridge.
This Somerset walk visits the highest point on Exmoor, Dunkery Beacon. Starting from Wheddon Cross, the highest village on Exmoor, the walk includes a variety of scenic interest including wooded combes and wild moorland.
Select an area below :


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Organ-On-A-Chip to Eliminate Animal Testing
Animal testing is necessary for the safety of drug development, but success in animal testing does not always indicate success in human trials. An animal's reaction to a drug can drastically vary from that of a human's which can lead to unforeseen adverse effects and inaccurate findings. In addition to health threats, there are financial risks associated with misleading results in an animal study. Clinical trials are expensive and a lot of money could potentially be wasted if a drug shows promise in animal trials but turns out to be ineffective in humans. Time, money, and even lives can be saved if there were a more accurate method of testing new drugs.
The Solution?
The organ on a chip is a microchip lined with human cells that exactly replicates the function and environment of full sized organs in the body. Take for example the lung on a chip. Inside the lung on a chip are two hollow channels separated by a porous membrane with one side coated in lung cells and the other in pulmonary cells. This structure creates two chambers, one allowing for air flow and the other for blood flow, mimicking the function and composition of the air sacs in a real human lung.
Organs on chips could be beneficial in many applications of the drug development world. Researchers could test a drug's impact on a certain part of the body and closely observe the pharmacokinetics and their impact on each system. This would help scientists better predict side effects and whether or not a certain drug is safe. When all of the organs on chips are put together, researchers will be able to discover exactly how the human body will react to the drug being administered. The implementation of organs on chips would provide more dependable results than that of animal testing. This is because trials on animals oftentimes produce outcomes that do not accurately reflect what would occur in humans. For example, an animal's body may metabolize drugs quicker or be more tolerant of a certain compound which are important factors to consider when developing a drug.
However promising it may seem, the organ on a chip has a ways to go before it eliminates animal testing. Insight into neurological side effects is gained from animal testing which is information that could not otherwise be observed. Additionally, Organs on chips and animal testing could be used complementary to create a more complete picture as scientists work to develop more alternatives. Regardless, a step towards eliminating animal testing is a monumental achievement and the organs on chips will certainly revolutionize early stage drug development like never before.
Attachments: Organ-On-A-Chip to Eliminate Animal Testing
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