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Friends, colleagues, collaborator and visitors,
Thank you for your interest in this website. I welcome you to a brief introduction to the content of this website.
It was with some trepidation that I decided to have a personal website that would condense in one place my professional activities as well as some of my extra-curricular projects and activities. Somehow, I thought that 2011 would be year to make this site accessible. Your feedback as to the effectiveness of this site would be greatly appreciated.
The headings and images of this site point to the different areas of my interests both professional and personal. From left to right these are: Crystal Edges (blog on themes broadly related to crystallography), Notes of a Protein Crystallographer (essays centered on Molecular Structure), Crystals and Life (Science Communication), Bernal's Picasso (drama of scientific discovery), The Sorcerer's Apprentice (lighter essays on drug-discovery), Efficiency-Based Drug Discovery (my vision for the future of drug-discovery), AtlasCBS (a server to map Chemico-Biological Space), Contact information and Consulting (Lecturing and consulting).
For further information, open the contact information tab and send me a brief e-mail to either my personal or my professional address. I would be more than pleased to establish a dialog with you from which I do hope that we can both benefit
Thank you again for your interest and I do look forward to hearing from you.
Visitors, colleagues and friends,
The last month of June was totally occupied with professional and personal activities. The celebration of an homage to my dear friend Ignacio Fita ('Ignasi' for friends and colleagues) of the Institute of Biología Molecular de Barcelona prompted an extended visit to Spain combining professional and personal activities.
The homage to Prof. Fita was organized by two of his early students, Prof. Nuria Verdaguer (IBMB, SBU-CSIC) and Prof. Alba Guarné (McGuill University, Montréal, Canada) and superbly coordinated logistically by Laia Vives (SBU-CSIC). You can read all the details at http://www.ibmb.csic.es/seminars-news/news/30-years-of-macromolecular-crystallography-in-barcelona. I presented a personal and historical lecture tracing our (Dr. Fita's and mine) professional and personal trajectories and linking them to the development and achievements of macromolecular crystallography in Barcelona.
More importantly, it was a memorable occasion for all friends, colleagues and collaborators of 'Ignasi' to get together for a couple of days of friendship and celebration in beautiful Barcelona.
(The content of the lecture is available upon request on a personal and confidential basis).
Prior to this meeting, June 14-15, I presented also a plenary lecture at the 10th World Congress on Medicinal Chemistry and Drug Design that took place also in Barcelona. This lecture was an oral and expanded version of the editorial 'Are SAR Tables Obsolete' presented previously in this News and Views and related to the editorial published in Drug Discovery Today approximately a year ago. See the 'Efficiency-Based Drug Design' tab for the pdf version of this lecture. Two additional important points emphasized in this lecture are the use of 'Alternative Variables' (i.e. Ligand Efficiency Indices) in Drug Discovery, and the introduction (or hopefully 'recollection' from younger years) of 'polar coordinates' to medicinal chemists to facilitate the navigation in Chemico-Biological Space, using the 'efficiency planes' already discussed within this website, as well as the AtlasCBS server.
Last, but not least, was the plenary lecture presentation at the 6IIBB2018 (6th International Iberian Biophysics Congress), in Castellón de la Plana (Comunidad Valenciana), Spain (June 20-22). http://www.sbe2018.com/
I was honored to be invited to present a lecture to the participants, no doubt due to my 'gray hair', and possibly also due to my early interests in the field of Structural Biology and Biophysics in my student days in Spain in the late 1960's and early 1970's.
I was indeed pleased and honored to address the attendees and younger participants. My intent was to inspire the younger generations of biophysicists using the achievements, insights and ideas of no other than Francis H.C. Crick. In preparation for the lecture, I enjoyed reading several books about and by the unique iconic figure of Francis Crick (references are presented in the last slide of the lecture).
The first part of the lecture draws from the earlier publication in the journal Arbor of the CSIC (see below),
celebrating the 100th year anniversary of the birth of Crystallography. The article is accessible from the following link: http://arbor.revistas.csic.es/index.php/arbor/issue/current. The second part is more speculative and presents the notion that, in the same way that 'What is Life' by E. Schrödinger inspired the early biophysicists in the 1940s, the ideas and insights that Crick pursued and published in the late part of his life with his close collaborator (Christof Koch), could inspire the younger generations of biophysicists. There is much to be done!
The full content of the lecture can be downloaded in pdf format here. [large file]
Our efforts related to developing Structure-Based methods and targets related to the Mycobacterium tuberculosis have reached a significant milestone with the recent publication in Acta Crystallographica D of the three-dimensional structure of the essential enzyme Fructose-1,6-Bisphosphatase (MtFBPase). This target has been shown by members of our group to be essential for the growth of the Tb mycobacterium in non-glucose media, such as glycerol. The structure belongs to the Class II FBPase, distinct to the Class I FBPases found in mammalian organisms. Although related to the equivalent enzyme in E. coli, the structure of MtFBPase is most similar to the one present in Synechocystis (blue-green algae, strain 6803).
The structure has been published in Acta Cryst D as an open-access publication. The article can be found at:
Full citation is: Acta Crystallographica Section D: Structural Biology, 2018, Volume D74, pgs. 321-331.
My colleagues and I look forward to your comments.
I have spent some intense months devoted to writing several chapters for a future book entitled 'Optimizing Structure-Based Drug Discovery'. The project is ongoing and will probably be published sometime in 2018. by J. Wiley. However, the momentum was derailed by some urgent health issues in the family and I could not devote as much time as I would have liked on research: first things first!
However, I am happy to report that there are two items of interest for readers following the exploration of the use of Ligand Efficiency Indices in Drug Discovery.
1. A chapter in a book entitled 'Software and Techniques for Bio-Molecular Modeling' edited by Dr. Azat Mukhametov and published by the Austin Publishing Group. This book is an interesting new addition to the references of techniques, concepts and software in molecular modeling for drug discovery. Chapter 2 describes the latest developments on the AtlasCBS concept, in particular the use of KNIME workflows to produce atlas-like plots and planes using simple KNIME modules. The entire text of the book, courtesy of the Austin Publishing Group can be found within the 'AtlasCBS' tab.
2. An editorial in Drug Discovery Today, entitled 'Are SAR tables obsolete' was published recently (Dec. 16.2016) on line questioning the utility of that icon of Medicinal Chemistry papers, 'The SAR table'. The argument is made that currently, with all the knowledge available regarding the physicochemical properties of the compounds discussed in medicinal chemistry papers, it might be better to condense this information in some kind of 2D-diagram. The full text of the article is available in the 'Efficiency-Based Drug Discovery' tab.
In commemoration of the International Year of Crystallography (IYCr2014) many organizations, journals and institutions have prepared special activities. Among them, the National Research Council of Spain (CSIC) has sponsored the publication of a special issue of its official publication entitled Arbor. This number has recently appeared on line and among the contributions the first article is a review of the advances in macromolecular crystallography in the second half of the 20th century from a personal perspective, related to the development of Dr. Cele Abad-Zapatero as a professional scientist, from his boyhood years in Spain, soon after the end of the Spanish Civil war.
The article is accessible from the following link:
http://arbor.revistas.csic.es/index.php/arbor/issue/current This article could be of interest to any budding scientist/crystallographer. Any interested reader should be able to download this or any other article from this special issue of
Arbor from the above website. Otherwise, copies can be requested from the author, from his e-mail address (see contact tab).
New blog posting at:
Image of the 'Chronophage Clock' in King's Parade in Cambridge
Among other things, this amazing clock is an homage to the
18th English clockmaker John Harrison who invented the
'grasshoper escapement' that allowed him to develop the
chronometers that permited the accurate determination of the
longitude at sea. A problem that had defied the most briliant minds
of his time. The clearly visible text in the lower ledge of the window is part of the full inscribed sentence on the window: Mundus transit et concupiscentia eius. This inscription is also present in the sun dial in one of the courtyards of Corpus Christi college. An reflection on the passing of time and our
desires and wishes.
A manuscript entitled 'Celebrating Macromolecular Crystallography: A Personal Perspective'is currently in press in a special edition of the Journal ARBOR, Ciencia, Pensamiento y Cultura . This special issue is intended to commemorate the International Year of Crystallography (IYCr2014). This article is a review of the origins and advances of structural biology in the second half of the 20th Century from the personal perspective of the author, as he matured as a professional scientist. The journal ARBOR is a publication of the Natural Research Council of Spain (CSIC, Consejo Superior de Investigaciones Cientificas). It will be published as an open-access and so if any reader is interested it can probably be found in the internet. Contact me if you are interested and have difficulties in obtaining a copy. The publication is imminent.
Return to UIC early in April. Working with UIC colleagues on SBDD projects
Currently in Cambridge, UK. I am spending two months (Feb 1-April 1) in the neighborhood of Cambridge, UK continuing the research on the update and applications of the AtlastCBS to drug discovery, and also on the use of Ligand Efficiency Indices (LEIs) as part of a Multiple Parameter Optimization (MPO) strategy to expedite drug discovery and to make it more rigorous. The hosting institutions are Optibrium, Ltd and the European Bioinformatics Institute (EBI) at the Wellcome campus in Hixton (ChEMBL: Chemical Biology group).
Participated in a Structure-Based Drug Design workshop/course at the Institute Pasteur de Montevideo (Montevideo, Uruguay, Nov. 3-8). This was an intensive drug discovery workshop in collaboration with Profs. P. Michels (University of Edinburg) and W. Hol (University of Washington, Seattle). The course was focused on novel methods and techniques for drug discovery with emphasis on Neglected Diseases. You can find more about the course and the Institute Pasteur de Montevideo here. There were lectures during an entire week , posters, and also practical sessions reviewing several computational techniques, among them 'docking techniques'. There was also a full practical session devoted to the use of the AtlasCBS webserver. (Images courtesy of Prof. W. Hol, University of Washington, Seattle).
Presented two talks at 23rd International Congress of Crystallography in Montreal, Canada (IUCr2014), Aug. 5-12. The first one was related to the presentation of Crystallography in a dramatic context. I reviewed the work that I have been doing on my own (Play: Picasso Meets Crystallography) and later in collaboration with Jill Campbell and Greg Gerhard (play: Bernal's Picasso) to present the concepts and history of Crystallography in a dramatic content. Further details can be found in the 'Bernal's Picasso' tab of this website. More details can also be found on the blog: www.crystaledges.org.
The second was related to the presence of symmetry in Art forms and
particularly in Rosewindows in Gothic Cathedrals. This presentation focused on the paper recently published in Acta Cryst vol. D70, published this past March. This is a theme that was mentioned before in this 'news and views' . The abstract of this presentation can also be presented in the www.crystaledges.org.
I will be happy to share more information if you are particularly interested.
Best wishes and enjoy the rest the summer.
There will be an upcoming paper in Future of Medicinal Chemistry (FMC), relating to the incorporation of the AtlasCBS and Ligand Efficiency framework into the StarDrop™ software (www.Optibrium.com). There have been quite a few publications in the field, particularly relating to the value of 'Ligand Efficiency Metrics' to guide drug discovery. Some of the papers are reviewed in the upcoming paper in FMC and perspectives for the future are presented.
Abad-Zapatero C, Champness EJ & Segall M. Alternative variables in drug discovery: promises and challenges. Future Med. Chem. 6(5), 577-593.
There is a pair of papers coming out in Acta Cryst D. One
about the structure of PurC from S. pneumoniae with my colleagues at UIC: N. Wolf,
M. Johnson and
Prof. L. Fung. A second, more intriguing, will be an essay on the series
'Notes of a
Protein Crystallographer' about the symmetry of the Rose Windows in
Cathedrals and the meaning of symmetry.
I'll provide details and links as soon as they come out.
I'll be in Cambridge, UK, Jan. 25-Feb. 4 working with my
colleagues at Optibrium on the implementation of the AtlasCBS software in
their StarDrop(TM) software
package. I should be back in Chicago, Feb. 8 and at the UIC campus soon
I will be in Paris, Jan. 20-24 for the events related to the
commemoration of the International Year of Crystallography (IYCr2014),
sponsored by
the IUCr and UNESCO. This is to celebrate the 100th year anniversary of the
unveiling of the very first crystallographic structure (NaCl) using X-rays
by the Bragg's (W.H. and W.L Bragg) in Cambridge, UK in 1913. Consult the
'crystaledges.org' for more details.
Leaving the UIC campus for a month stay in Europe.
Landing in Paris, Jan. 11, I'll be in Saarbrucken, Germany,
giving a Workshop on Protein Crystallography and Structure-Based
Drug Design in the laboratory of Prof. Rolf Hartmann, University of
Saarlandes, Department of Drug Optimization.
Happy New Year and best wishes to you and your family,
friends and colleagues for 2014 and beyond. See the last posting on the blog
for a reflective poem entitled 'Season's Lament' about Christmas trees.
Returned to UIC after first successful workshop about
the concepts and usage of the AtlasCBS concepts and tool
at the Helmholtz Institute of Pharmaceutical Research in Saarbruecken,
Germany (Sept. 30-Oct. 1).
The workshop was run in collaboration with the colleagues of Optibrium,
Ltd (UK) that now offers the AtlasCBS application as an add-on to their
software Stardrop(TM). Link
After the workshop, attended meeting in Getxo, Bilbao
(Spain) in honor of Jorge Navaza (Grenoble, France), recognizing his
contributions to the implementation of the Fast Rotation Function and
other mathematical and computational tools in crystallography and electron
microscopy. (See blog: Crystal Edges).
Currently at UIC. Blog 'Crystal Edges' inaugurated to
commemorate the International Year of Crystallography in 2014 (IYCr2014).
Please visit new leftmost tab 'Crystal Edges'.
Visiting professor at the University of Alcala de Henares (Madrid)
in the Department of Pharmacology, sponsored by the Foundation
Giner de los Rios to update, develop the AtlasCBS server and train
students and medicinal chemistry professionals.
Laboratory of Prof. F. Gago. Feb.-June.2013.
Recently published book: Ligand Efficiency Indices for Drug Discovery Towards an Atlas--Guided Paradigm See Flyer >>
Recent papers:
Published paper on humidity control in macromolecular crystallography
Oliete et al. Elastic and inelastic diffraction changes upon variation of the relative humidity environment of PurE crystals. Acta Cryst. (2013) D69, 194-212.
Recent book summarizing the concepts and ideas related to Ligand
Efficiency Indices in Drug-Discovery:
'Ligand Efficiency Indices for Drug Discovery:
Towards and Atlas-Guided Paradigm'
Read More about the recent article in El Pais.
Cortes-Cabrera, A., Morreale, A., Gago, F. and C. Abad-Zapatero. AtlasCBS: a web server to map and explore chemico-biological space. J.
Comp. Aided Mol. Design. 2012. DOI 10.1007/s10822-012-9587-5. Read More
Contribution of indazolinone tautomers to kinase activity. Vasudevan A, Verzal MK, Villamil CI, Stewart KD, Abad-Zapatero C, Oie T,
Djuric SW. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4502-5.
Exploration of diverse hinge-binding scaffolds for selective Aurora
kinase inhibitors.
Ji Z, Dai Y, Abad-Zapatero C, Albert DH, Bouska JJ, Glaser KB, Marcotte
PA, Soni NB, Magoc TJ, Stewart KD, Wei RQ, Davidsen SK, Michaelides MR. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4528-31. Epub 2012 Jun 7.
Notes of a protein crystallographer: on the high-resolution structure of the PDB growth rate Abad-Zapatero, C. Acta Cryst. (2012). D68, 613-617
Article in El Pais commemorating the 40th anniversary of the PDB, at a meeting in Cold Spring Harbor Laboratory, Oct. 28-30, 2011.
AtlasCBS server beta-version available (see Tab).
Humidity control can compensate for the damage induced in protein crystals by alien solutions. C. Abad-Zapatero, R. Oliete, S. Rodriguez-Puente, J. Pous, L. Martinelli, M. E. Johnson and A. Guasch. Acta Crysta. (2011) F67, 1300-1308.
Discovery of potent and selective thienopyrimidine inhibitors of Aurora kinases William J. McClellan, Yujia Dai, Cele .Abad-Zapatero, Daniel H. Albert, Jennifer J. Bouska, Keith B. Glaser, Terry J. Magoc, Patrick A. Marcotte, Donald J. Osterling, Kent D. Stewart, Steven K. Davidsen, Michael R. Michaelides. Bioorganic & Medicinal Chemistry Letters 21 (2011) 5620–5624.
Crystallization and preliminary X-ray Characterization of the
glpX-encoded class II fructose-1,6-bisphosphatase from
Mycobacterium tuberculosis.S
Gutka, H., S.G. Franzblau, F. Movahedzadeh and Cele Abad-Zapatero. (2011). Acta Cryst. Section F, F67, 710-173.
Ligand Efficiency Indices (LEIs): More than a Simple Efficiency Yardstick. (2011). Cele Abad-Zapatero & D. Blassi. Review in Molecular Informatics. 30(2-3), 122-132.
Time-Trajectories in Efficiency Maps as Effective Guides for Drug Discovery Efforts. (2011). Serge Christmann-Franck, Daniel Cravo and Cele Abad-Zapatero. Molecular Informatics. 30 (2-3), 137-144.
Retrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies. (2011). Daniel Blasi, Gemma Arsequell, Gregori Valencia, Joan Nieto, Antoni Planas, Marta Pinto, Nuria B. Centeno, Cele Abad-Zapatero, Jordi Quintana. Molecular Informatics. 30 (2-3), 161-167.
Recent article about 4th generation synchrotons appeared in the electronic version of the Spanish Newspaper 'El País' Feb. 15, 2011.
Destellos brillantes y ultracortos iluminarán la nueva biología estructural. More...
Recent publication of the AtlasCBS concept in Drug Discovery Today.
Ligand Efficiency Indices for an effective mapping of Chemico-Biological Space: the concept of an atlas-like representation. (2010). Drug Discovery Today. 15: 804-811. C. Abad-Zapatero, O. Perišić, J. Wass, A. P. Bento, J. Overington, B. Al-Lazikani, M. E. Johnson.
A novel non-ATP site in Protein Kinases of the MAP group (an interesting paper of SBDD).
Discovery and Characterization of non-ATP site Inhibitors of the Mitogen Activated Protein (MAP) Kinases. Chemical Biology. (2010). K. M. Comess, C. Sun, C. Abad-Zapatero, D. Borhani, E. Goedken, M. Argiriardi, D. R. Groebe, R. J. Gum, Y. Jia, J. E. Clampit, D. L. Haasch, H. T. Smith, S. Wang, D. Song, M. L. Coen, T. E. Cloutier, H. Tang, X. Cheng, C. Quinn, B. Liu, Z. Xin, G. Liu, E. H. Fry, V. Stoll, T. I. Ng, D. Banach, D. Marcotte, D. J. Burns, P. J. Hajduk. American Chemical Society. Chemical Biology. in press. (available online).
Current affiliation (May 1-July 31, 2011):
Visiting Professorship at the Center Molecular Biology Severo Ochoa (CBMSO), Madrid, Spain,
in the group of Bioinformatics of Dr. A. Morreale, in collaboration with Prof. F. Gago (University of Alcala de Henares, Madrid, Spain) to develop and implement the AtlasCBS server. Sponsored by the Spanish Ministry of Science and Technology.
U.S. PATENT NO. 7,795,248. Issue date, Sept 14, 2010.
Title: SUBSTITUTED 7,8-DIHYDRO-1H-PYRMIDO[4,5-B][1,4]DIAZEPIN-4-AMINES ARE NOVEL KINASE INHIBITORS. V. Gracias, C. Abad-Zapatero, Stevan W. Djuric et al. Novel protein kinase inhibitors.


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Quote from: Slinky2* on April 14, 2012, 01:40:09 pmMe Gusta moonPlease don't call it that. :\
Me Gusta moon
What is this, Donkey Kong Country in Space?
Does anyone know what video I'm talking about?
Quote from: 762 on June 05, 2010, 10:19:32 pmDoes anyone know what video I'm talking about?The one with the Creature Stage Screeble living on a peninsula?
The Creature Stage sucked totally. It lacked fun, something I think the whole game did, it lacked fun and challenge.
There is, of course, a difference between having a laugh with someone, and having a laugh at their expense
What are you talking about? The CS had the most "game" of all the lower levells.
The cell stage lived up to all it's expectations given by the GDC'05 video. That's why it's the best stage.
(Followed by Civilisation stage, which also didn't have any expectations attached to it due to the lack of demonstrations.)
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Journal of the South African Veterinary Association
On-line version ISSN 2224-9435
Print version ISSN 1019-9128
J. S. Afr. Vet. Assoc. vol.83 n.1 Pretoria Jan. 2012
Review of Small animal dermatology
Martin Briggs
Newlands Veterinary Clinic, Cape Town, South Africa
Book Title: Small animal dermatology (Revised and updated)
Editor: Karen A. Moriello
Publisher: Manson Publishing/The Veterinary Press, London; 2011, R350.00*
The manual appears in a compact soft-cover edition and is well illustrated with photographs. In this way it serves as a quick reference for the investigation of dermatological conditions in small animals. However, the format (A5) restricts the size of the images, and hence their clarity. The manual is written in the question and answer format, and is thus useful as a test of the Veterinary clinician's knowledge. However, covering the entire curriculum of Veterinary Dermatology in this format has made it cumbersome, as searching for the answers (unless they appear in adjacent pages) can be arduous for the busy practitioner.
Southern Africa suffers from a dearth of texts relevant to small animal dermatology, which has resulted in veterinary practitioners devoting valuable time to researching foreign texts about dermatological diseases that are not encountered in Southern Africa: many chapters in this manual are thus irrelevant to us. Question 1 of the text involves a northern hemisphere condition, namely hookworm dermatitis, which is unlikely to be encountered in our sunny climate. Question 2 involves a breed of dog unlikely to be seen in South Africa. The diagnosis, keratoacanthoma, which is breed related, is also unlikely to be encountered here (although it is a rare possibility in German Shepherd dogs). Questions 10 and 11 (pp. 14, 15) are similarly irrelevant here, as they concern blastomycosis. Question 61 (Bowen's disease) is irrelevant for South Africa. Question 78 discusses polydactyly, although breeds showing this genetic defect have, fortunately, not been introduced to Southern Africa. Piedra (pp. 105, 106) and Timentin (p. 121) are, thus, not relevant here. Cuterebra myasis (p. 135) is unlikely here with Cordylobia being the particular myasis encountered in Southern Africa. Question 175 is also irrelevant here (zygomycosis).
For assistance in perusing this manual, it should be noted that the many abbreviations employed in the text are explained in a separate list which appears on the last page. An important abbreviation, that of MDR1 (p. 66), is absent from the list and this remains unexplained. In Question 81, a differential diagnosis for thin skin is given erroneously as hypothyroidism, because the skin is thickened with this disease. In Question 83 (p. 90), South African practitioners may be confused by the term 'pyotraumatic dermatitis', as this condition is known here as 'acute moist dermatitis', or simply 'hotspot'. The related Question, no. 84 (p. 91), asks for the common causes for the recurrence of this disease, but the answer (p. 92) ignores demodicosis - a frequent (and commonly missed) cause of relapsing acute moist dermatitis in Southern Africa. Question 104 (p. 111) shows a facial lesion in a cat where ectoparasite causes are omitted, these being mites (Notoedres, Otodectes, Demodex, Cheyletiella), as well as fleas and mosquitoes. The given diagnosis of sporotrichosis has no relevance here. Question 169 appears to be a repeat of 161 (feline eosinophilic granuloma complex). In South Africa, hyperthyroidism would be a differential of Question 182 but this possibility is omitted. Question 183 appears to be a repeat of Question 166, and this in turn a repeat of 153 and 73, concerning demodicosis. This results in the reader having to peruse various sections of the manual concurrently. A comprehensive index assists in exploring individual diseases. However, 'Stud tail' is incorrectly indexed as it does not appear to have any connection to its designated Question 133.
The author has chosen this format of questions and answers in an attempt to cover the complete spectrum for presenting symptoms as well as all possible aetiologies. Although this would probably be more appropriately achieved in the classic textbook format, which deals with each disease in a separate chapter, clinicians could find useful guidelines in the various questions and answers whilst consulting other texts concurrently.
Correspondence to:
Martin Briggs
Newlands Veterinary Clinic
Paradise Road
Newlands 7700
Cape Town
* Book price at time of review


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The average Georgia Bulldogs tickets price will cost you between $79 and $2697, if you are looking for the cheapest seats then catch the event being held at the Vanderbilt Stadium Parking Lots, Nashville on 31/08/2019. The average ticket will cost you the highest on 06/09/2019 at the Sanford Stadium, Athens.
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Market Scene: Redmond Farmers' Market in Washington
It's an obvious thing to say, but the Pacific Northwest is rainy. So rainy, in fact, that I couldn't even take photos and visit my own neighborhood farmers' market in time to write this article! Apologies to the city where I live, the quaint and rural-wonderful Duvall, nestled east of Seattle, in the Cherry Valley, for not being properly represented in this Market Scene. And boo to angry droplets pouring from the sky, making it tough to take good photos! But fear not, I was able to head to the neighboring city of Redmond, which has a lovely market that we've been regularly visiting for several years, bringing forth fall colors and flavors!
Redmond is a suburb dotted with pine trees and remnants of its previous life as a quiet farming town. It may be known more as a bedroom community for Microsoft, but still has its moment of countrytime charm, especially as the chill of autumn creeps in and the hayride and corn mazes are starting, the pumpkin patches are getting ready to harvest, and signs for fresh-pressed cider are appearing.
The Redmond Saturday Market is located in the open gravel lot next to the Redmond Town Center, a large retail and business center in the downtown area of the city. It's open every Saturday from 9 a.m. to 3 p.m. and offers fresh fruits and vegetables, as well as prepared foods and craft items. They also have a small stage area, so it's a family-friendly place to bring the whole family (dogs, too) and listen to some music while shopping.
Because a lot of farmers' markets aren't open year-round, now is the best time to go and take advantage of the ones who allow craft goods vendors to sell their wares. The holidays are coming up, and it's such a nice opportunity to buy something locally-made. The iridescent glassware from Wileyware, a Seattle-based company that makes hand-blown glasses with a colorful base that changes in the light, is a festive way to add some sparkle to a plain glass of water. The handmade soaps from Paula's Soaps make a sweet and fragrant gift, with their natural and gentle products. Even edible items make for good gifts - a jar of apple jam from Hermitage Pantry by Tapert Studios and a bag of locally grown hazelnuts from Holmquist can be a sample of local flavor for a visitor to the area.
Much like the leaves beginning to turn a fiery hue, the seasonal harvest is showing off its own bright colors. The last of summer's stone fruit is coming out—there are still candy-sweet white nectarines and small, slightly oblong Italian plums dotting the fruit stands. Magana Farms from Sunnyside on the eastern part of the state, had piles of the late harvest plums, nectarines and tomatoes. Italian plums tend to have a milder flavor, not as sweet, and they are a nice filler for tarts or cobblers. The combination of the pleasantly sweet fruit and the bitter skin make it a nice balance for savory uses, for example, they can be split, pitted and roasted with a bit of goat cheese for a delicious snack or served over salad greens.
Also displayed on Magana Farms' table were piles of green beans, immediately making you picture green bean casseroles, as well as long, multicolored banana peppers. Piled high in bins, they jump out in bold Christmas reds and greens, plus a few in the pale yellow-green ones most people are probably used to seeing. Peppers of all sorts are hitting the tables, and it's nice to see them in a more natural color and shape, not the perfect, symmetrical, one-tone hue that most markets sell. Tonnemaker Hill Farm, a certified organic farm from Royal City, had a beautiful array of multicolored bell peppers. Their bumpy, irregular shapes were reminiscent of heirloom tomatoes, as was its multicolored skin, sometimes going from green, to purple, to red. The flavors of the peppers don't necessarily vary between the different colors, except the brighter tones are a little sweeter from being riper. The purple bell peppers are beautiful when enjoyed raw, mostly because when they cook down, the color fades into a less appealing brownish color (so if you happen to find purple peppers, save them for salads).
Tonnemaker had an impressive array of organic eggplant, including the long, thinner-skinned Japanese variety, the egg-shaped purple, the white "graffiti" eggplant, and the more oblong all-white eggplant. It's one of those vegetables that looks more beautiful raw, since the color will dull during cooking, but they're a great addition to stews and make good sides. Overcook them and they become mushy (which has inspired a community of eggplant haters) but prepared properly, they are great flavor sponges. The white eggplant is known for having a more solid texture and also less bitter, so it's a good variety to offer as an olive branch to the anti-eggplant crowd out there—don't hold it against the well-meaning aubergine, there's still good flavor to be had! Give eggplant a chance!
The vendors offering prepared foods and specialty items change periodically. It's been crepes, wood-fire pizza and tamales from one Saturday to the next. The latest were the goodfellas of Wiseguy Dinner Club, offering a new take on a hot Italian sub. They were drawing in the crowds with a giant pan of sizzling Italian sausage and peppers, and instead of pouring it over a split roll, they hollow out the center of a section of baguette and fill it with the spicy mixture. It makes for easier and less-messy eating while shopping.
A favorite all-season vendor has been Samish Bay Cheese, a Skagit County-based cheesemaker that, along with organic cheese, sells yogurt, eggs, and meat. They always have a unique array of different flavors and styles of cheese on display and available for sampling. They've made cheese dotted with fresh chives or dusted with bittersweet cocoa powder, plus they sell fresh cheeses like mozzarella and the wonderful squeak of fresh curds.
Because of the incoming cooler months, the more delicate items are hitting their "last call," so enjoy them in their peak flavor. Now is a good time to buy up items like tomatoes and fresh basil, and then prepare them for winter months by making tomato sauce or pesto. For the last of the summer fruit, stock up on your favorites and make preserves. It's a resourceful way to really cherish a changing season and save those flavors for the cold days and nights, when those bright flavors will be a happy respite from grey skies.
Items to look forward to: fall squash! Get ready for the incoming parade of butternut and acorn varieties, along with pumpkins. All are wonderful when cooked and blended into soups, or simply roasted and used as a side dish. If you have the chance to make your own pumpkin pie from scratch this year, I highly recommend it! Happy autumn wishes to all, and make the most of your farmers markets the rest of the year!
Info for Visiting the Market
Redmond Saturday Market
Every Saturday, from 9 a.m. to 3 p.m., at 7730 Leary Way NE, Redmond WA 98052
Parking: Park your car at the Redmond Town Center mall lots and walk over. This market is dog friendly, so definitely bring your fuzzy friend!
For those who live in the area, upcoming events include: Redmond Saturday Market's Apple Cup on October 9, offering a taste of all the different Washington apples and the Howl-o-Ween pet costume parade on October 20, which is also the last day of the market.
In Season
Basil Beets Cabbage Cantaloupe Carrots Cauliflower Corn Eggplant Garlic Green beans Peppers Plums Onions - Walla Walla Potatoes Radishes Squash - early fall, butternut, acorn and sugar pumpkins Tomatoes Zucchini
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UAS assesses academic standing only for students admitted to a degree program. Students who fall below "good standing" will be notified and directed to seek assistance from an academic advisor. The following four levels of academic standings are:
Good Standing
Students are in academic good standing when they have a cumulative grade point average of 2.00 or higher (3.00 or higher for graduate students) and a recent semester grade point average of 2.00 or higher (3.00 or higher for graduate students) First-semester students are presumed to be in academic good standing during their initial semester unless the student has been admitted on probationary status. Please note that Good Standing is not the same as Satisfactory Academic Progress for Financial Aid. See the policies regarding Verification of Academic Progress for students receiving financial aid.
Academic Warning
Any time a student's semester GPA drops below a 2.00, he or she will be given an academic warning. Students will be required to meet with an academic advisor prior to registering for the subsequent semester.
Academic Probation
If a student's cumulative and/ or semester GPA drops below a 2.00, he or she will be placed on academic probation. A student can only be removed from probation status by raising his or her cumulative GPA to a 2.00 within one semester after being placed on academic probation. Students will be required to meet with an academic advisor prior to registering for the subsequent semester.
Academic Program Removal
Any student who remains on academic probation for two consecutive semesters of attendance will be removed from his or her degree program. An application fee for readmission will not be required. If a student's cumulative GPA is less than a
2.00, but he or she earns a semester GPA above a 2.00, the University will recognize the student's attempt to reach academic good standing and the student will continue on probation until both the semester and cumulative GPAs are above a 2.00.
Graduate Probation
When a student's cumulative graduate program GPA has dropped below 3.00, the student is placed on academic probation and dropped from candidacy status (if applicable). Terms and conditions of the probation are determined by the program dean or program advisor. These may include specific conditions and/or credit limitations the student must meet during his or her next enrollment at UAS. When the student is removed from academic probation, the student should contact his or her advisor to reapply for advancement to candidacy if applicable.
A student who has not been removed from academic probation within two consecutively enrolled semesters or two summer semesters in succession will be removed from the program. Should the suspended student wish to continue to pursue a degree, the student must submit a new application for admission (including supporting documents but not including the application fee).


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Criminal Forms
Most forms on this website are in Microsoft Word (.DOC/.DOCX), Corel WordPerfect (.WPD) and/or Adobe Acrobat (.PDF) formats. We encourage you to use the .PDF format when possible as it is the most compatible.
Working with PDF files will require one of the many available PDF readers/writers to open the document. If you're using Adobe Reader and are having trouble opening a form, please update your free reader to the latest version (get.adobe.com/reader). In order to edit, create and save PDF files, you will need a PDF writer, such as any of the the full versions of Adobe Acrobat, or there are many other writers available for free or fee.
If you are still having difficulty with a form, please notify us via our Web Help form.
Visit the Federal Courts Website for other available forms (http://www.uscourts.gov/FormsAndFees.aspx)


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Amazing Solutions
Nanosurfaces Industries Srl., is being acquired by Eurocoating SpA
Engineered ceramics leader invests to meet growing OEM orthopedic implant demand.
Our proven, five-stage CO-INNOVATION™ process has resulted in the successful launch of over 150 medical devices by incorporating services that go well beyond traditional product development.
CoorsTek Medical employees' number one priority is to create outstanding value for our customers. We do what we say, and we say what we mean. We work together to make our company the best so we can keep making lives measurably better each and every day.
CoorsTek Medical works with product innovators and manufacturers to turn great ideas into life-enhancing realities—making Lives Measurably Better.
Read more
Our vision, mission, and values drive everything we do. CoorsTek Medical is the partner of choice for medical innovators and medical-device providers worldwide whose success requires access to leading-edge medical device development experts.


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Lisa Smith-Batchen had long dreamed of running across America, but in the mystifying mind of an ultramarathoner, it didn't seem quite extraordinary enough.
So Smith-Batchen, one of the world's foremost endurance athletes, upped the ante with an unprecedented challenge: run 50 miles in each of the 50 states, within 62 days. She's running mostly by herself, but not just for herself, as her goal is to raise $1 million for orphan charities and spread awareness of the plight of foster children.
"I really feel that by the end of this run, a million people will know about it," Smith-Batchen, 49, said by phone during a rest day between her runs in West Virginia and Virginia. "And if everyone just gives $1, we all can make such a huge difference."
Smith-Batchen kicked off her challenge, dubbed Running Hope Through America, on April 19 by running 50 miles in New Jersey, followed the next day by 50 miles in New York, then to Connecticut the next day for another 50 miles — and so on. By the time she finishes her last stretch in Idaho on June 19, she will have run 2,500 miles. (Visit
for her route and other information.)
It's a monumental feat even for a seasoned ultramarathoner like Smith-Batchen, who is the only American to have won the women's division of Marathon Des Sables, a 150-mile race through the Sahara Desert, and who this summer will run her 10th Badwater Ultramarathon, a 135-mile race in Death Valley.
But the cause keeps her feet pounding.
Who will benefit?
All of the money raised will be split among three charities: AIDS Orphans Rising, which provides food, housing and education to children around the world who have lost their parents to AIDS; the Caring House Project, a Haiti-focused foundation to help the homeless; and The Orphan Foundation of America, which provides grants and support to youth aging out of the foster system. The funds will be distributed by Smith-Batchen's Dreamchaser Foundation, a nonprofit she founded in 2008 to channel her fundraising and to encourage other athletes to use their love of sport for charitable ends.
Smith-Batchen, who has adopted three children — 4-year-old Gabby, 7-year-old Annabella and another child who was heartbreakingly taken back by the birth mother — has a personal stake in the mission. But she said her inspiration to run for charity comes from her friend and fellow ultrarunner Sister Mary Beth Lloyd, a member of the order of the Religious Teachers Filippini, who in 2008 received the Path to Peace Foundation's Servitor Pacis award for her work with AIDS orphans.
"Everyone has such gifts, such talents, and mine happens to be running," said Smith-Batchen, who lives in Driggs, Idaho. "And I know God gave me these legs for a reason."
How is she doing it?
Her current challenge is as arduous as it sounds.
Smith-Batchen, whose record time for a 50-miler is 6 hours and 40 minutes, is giving herself about 14 hours each day to finish. She wakes at about 4:30 a.m., and runs from 5:30 a.m. until 7 or 8 p.m.After eating, soaking in an ice bath and getting massaged, her body finally winds down enough for bed around midnight. She sleeps in compression socks with her legs elevated and has been averaging 4 1/2 hours of sleep per night.
"I didn't think I'd become so needy," said Smith-Batchen, who on her rest day was catching up on her work as an online running coach. "People help me take off my socks."
Showing support
Supporters have joined Smith-Batchen for stretches of the run.
Lloyd, 62, has been running with Smith-Batchen about 20 miles per day — in her full nun's habit, as required by her order. Kids from the Orphan Foundation, which helps former foster youth 18 to 26 with financing, coaching and moral support as they try to become successful adults, also have been running with Smith-Batchen.
"We're updating our kids every step of the way," said Eileen McCaffrey, chief executive of Orphan Foundation, which has never been part of such a fundraising event before. "The money will be fantastic, but it's also that she's bringing the message to so many people."
After a punishing 50-mile slog through Vermont, where it was windy, snowing, raining and sleeting, Smith-Batchen said she felt uplifted during her run through Pennsylvania, where, for the last five miles, a group of students ran silently behind her.
"Nobody talked, nobody said anything," Smith-Batchen said. "At the end, it was just graceful."
How to combine fitness with charity
Lisa Smith-Batchen, who didn't make her high school cross-country team because the coach told her she was too slow, has been running competitively since she was 21, when a friend invited her to a Turkey Trot race and Smith-Batchen took first place, winning a 20-pound turkey.
Countless races and medals later, Smith-Batchen said her deepest satisfaction comes from using her gift to help others.
"Use your talent, use your passion, use your love for a greater purpose other than yourself," she said. "There's much greater reward for me personally and for everyone I see who does it for charity."
For people hoping to combine their passion for fitness with charity, a good place to start is active.com, where you can search and register for activities from biking to bowling. The Web site, part of the Active Network, is the largest participatory sports site on the Internet, with more than 100,000 activities nationwide. Other sites, including activegiving.com, which is part of the Active Network, and giveforward.com, let you set up a donation page where friends can make contributions to a cause or charity of your choice.
Michele Crepeau, industry manager for the giving market at the Active Network, offered advice for how to effectively sweat with a purpose.
•Figure out what sport interests you, because it's important that you like what you're doing to stay engaged. It might be running or it might be mustache-growing.
•Be realistic about what you can accomplish. If you've never run a race before, start out with a 5K, then build to a 10K and a half marathon before attempting the marathon.
•Decide whether you want to stay local or participate in a destination event. You usually can ask for more money if you travel for the event.
•Determine how much time you have to train. Will it fit in your busy schedule, and are you starting far enough in advance?
•Decide if you want to train on your own, online or with a group. People often are more engaged if they train with a group because of the camaraderie and competition.
•Attend a race or a kickoff meeting. Just seeing other people excited may inspire you to sign up.
•Ideally, sweat for a charity you have a personal connection to. If you participate in an event already associated with a charity, it may have an official donation page.
•Set up an aggressive fundraising goal, but be mindful of who your friends are and how much they'll really be able to give. The more difficult the event, the more money you can ask for.
•Use social networking to spread the word about your project, dropping the link to your donation page on Facebook and Twitter, as well as blasting an e-mail to everyone in your address book. Give continual updates on your training. Go old-school with fundraising bake sales or auctions.
•After the event, post your finish-line picture and thank everyone for their support. Give people one more chance to give.
The Chicago leg
Lisa Smith-Batchen brings her million-dollar legs to Chicago on Sunday, running 50 miles along the lakefront in a loop between Foster Avenue and the Field Museum. She'll start at Diversey Harbor at 5:30 a.m. and will end at the same place 50 miles later, probably around 7 p.m. Anyone who wishes to can join her, though Smith-Batchen's team will not be providing aid stations for other runners.
The run in Chicago is a homecoming of sorts for Smith-Batchen, who grew up in Deerfield.
"I think Illinois is going to be one of best states ever," Smith-Batchen said. "I have lots of high school friends who said they might join me."


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Core Principles | Mission | Philosophy | News
The Quality Management Branch (QMB) is responsible for assuring that contractors funded by the Texas Health and Human Services Commission (HHSc) meet standards and requirements of the department. Staff of the Branch also assist contractors in identifying opportunities and avenues to improve services.
Quality Management involves three major goals which can be visualized in the Quality Management triangle.
Defining Quality
Measuring Quality
Improving Quality
Defining Quality
Measuring Quality
Improving Quality
The QMB conducts on-site and desk reviews of the services delivered by contractors and providers to assure that pre-determined standards of care are met. The QMB also works with contractors to improve efficiency and effectiveness.
Quality is of uppermost importance in the delivery of health care services and the QMB strives to assure Texans served by contractors receive quality care.
The Quality Management staff seek to assure that high quality comprehensive services, within the framework of current standards and contracts, are delivered to individuals in a cost effective manner. Services delivered shall promote human dignity, respecting cultural and individual differences, preserving freedom of choice while maintaining individual confidentiality.
To assure open and honest communication between Health and Human Services, our contractors/providers and those who receive health care services. This communication should foster individual thinking and constructive criticism. We believe in being open, ethical, responsive, accountable and dedicated to the public we serve.
Child Abuse Reporting Requirements [previously Rider 19, 23, 27, 11, 18, 14, and 33]
Note: When a report to the Department of Family and Protective Services (DFPS) is indicated and the situation is not an emergency, contractors/providers are encouraged to use the DFPS Statewide Abuse, Neglect and Exploitation Reporting System found on the DFPS website: https://www.txabusehotline.org/Login/Default.aspx
DSHS Standards for Public Health Clinic Services
Client Service Standards for Public Health and Community Clinics and are intended to augment program-specific standards. The standards address common components foradministering public health clinics to assure the delivery of quality health services.
DSHS Standards for Public Health Clinic Services (27KB, PDF)
Texas WICQuality Management Branch4616 W Howard Ln Ste 275Austin, TX 78728
Phone: (512) 341-4605
(512) 341-4406
Email the Quality Management Branch for additional information.
Texas Homeland Security | Statewide Search | Texas.gov | Texas Veterans Portal | Privacy Practices | Report Fraud, Waste, and Abuse


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Selling an old computer is always an exercise in heartbreak. There are few experiences quite as unpleasant as realizing that the tower you bought for around three grand a few years ago is now down into the three-digit price range. And while there's not a lot to be done about that, you can at least prepare yourself in advance, to lessen the shock.
Mac2Sell is a site that allows you to find the current value of any Mac you might be looking to sell. You start by choosing your country (of which there are dozens of selections) and selecting the type of system you want to sell. All that's left is to add your options and get the price in your local currency.
Like many pricing guides, the values seem a little higher than what you can expect to actually get from a sale. I priced out several systems I have around the office, and Mac2Sell's value was at least a few hundred dollars more than what seems to be the going rate on eBay in each case. Some of this may be accounted for by the fact that all estimates seem to include VAT, a tax generally associated with some European countries. This appears to be added even when you select a country that doesn't collect it. In general, Mac2Sell's value estimates might serve more value as a good place to start negotiations as the seller.
Accurate or not, it's a fun exercise even if you aren't planning to sell anything. Now if only I could find somewhere to appraise my collection of antique pickle jars...


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Evolution Cycles is proud to be the official UK supplier for NOBL rims and hubs, superior design and construction carbon rims custom handbuilt by our own very experienced in-house DT-Swiss certified wheelbuilder Kevin Head. Warranty As an official distributor for NOBL rims we are now able to match their excellent warranty on all rims and wheels purchased directly from us.
Please visit NOBL website for further details, tech info and everything to do with NOBL
About NOBL
Born out of the unforgiving terrain of the Pacific Northwest in 2012, NOBL Wheels has humble origins. What began as a hobby for Trevor Howard: blending his aircraft composites training and love of wheel building from trials riding, turned into a full time job. Trevor partnered with Ryan Kononoff, a successful entrepreneur in the tech sector, to take NOBL to the next level. In 2013, after recognizing a void in the market, NOBL sought to produce the toughest and highest value carbon wheelsets available.
Read all about NOBL Company History!
Bike Mag - 2017 NOBL 29" TR36 Product Review - By: Ryan Cleek
Pinkbike - 2016 NOBL 27.5" TR33 Product Review - By: Vernon Felton
Blister Review - 2017 NOBL 27.5" TR33 Product Review - By: Branham Snyder
NSMB - 2016 NOBL TR33 Interview - By: Jon Harris
Rims now carry a 30 month manufacturers warranty. If the rim was purchased as a fully built wheelset from us we will include the replacement build free of charge. Simply contact us with full details.
[Lifetime crash replacement - We offer a replacement rim at 50% of MSRP (excludes rebuild costs).
As an official distributor for NOBL rims we are now able to match their excellent warranty on all rims and wheels purchased directly from us.
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Subscribe and stay up-to-date with the latest news and great offers from DEKALB, Asgrow and Deltapine.
At DEKALB®, we focus our energies on doing all we can to move your corn expectations forward by improving performance no matter the challenge. That mission has made us an industry leader for over 100 years. You can use this site to explore our commitment to innovation, where we're heading and the many ways we help you achieve the yield performance you demand from your acres.
We thank you for choosing DEKALB® and invite you to start where we start, with our global breeding program.
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Beckwood Press Implements New ERP System
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Sunday, January 1, 2012
Hydraulic-press manufacturer Beckwood Press Co., St. Louis, MO, has implemented a new enterprise-resource-planning (ERP) system designed to provide its customers with access to manufacturing schedules, and the ability to order spare and replacement components on-demand. Also accessible are Gantt charts to document the manufacturing process in real time, and manuals, approval drawings and component documentation.
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|In our weekly story meetings, we spend a lot of time talking about what's in the news, research being published in the journals or discussed at meetings, and thinking about the latest trends. But there's often some time spent to simpler questions, such as this week's query from Ira: You deliver your prescription to an optician, and they return with a pair of eyeglass lenses tailored precisely to your personal vision quirks. How do they do that? In this segment, we'll try to find out.


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Originally published December 3, 2012 at 8:01 PM | Page modified December 3, 2012 at 10:24 PM
As society sheds paper, an industry shrinks
The North American paper industry is in rapid decline. Towns from Washington to the coast of Maine have lost more than a hundred paper mills in a wave of consolidation in little more than a decade — a trend most people in the industry expect to continue.
Minneapolis Star Tribune
GRAND RAPIDS, Minn. —
Something stunning happens at 60 mph inside the UPM Blandin paper mill.
A thin layer of damp white pulp, flattened between forming fabric as it races through a gauntlet of heavy rollers, slips free from its forms.
It ripples like a bedsheet on a clothesline, but it holds together.
The newborn paper shoots forward through heated rollers to be pressed and dried, then coated and polished before spooling onto a giant roll.
More than 1,000 tons of shiny white paper for magazines and catalogs come off the line every day.
But this is yesterday's miracle.
The North American paper industry is in rapid decline.
Mills have cut thousands of workers and are competing for a shrinking market.
A mill in Sartell, Minn., that closed this year after a Memorial Day explosion was the latest to go dark.
"It's kind of disheartening," said Jim Skurla, an economist at the University of Minnesota, Duluth. "Paper's never going to disappear, but it's going to be smaller than it has been."
River towns in the forest from Washington to the coast of Maine have lost more than a hundred paper mills in a wave of consolidation in little more than a decade — a trend most people in the industry expect to continue.
North American demand for three types of coated and supercalendered paper — shiny magazine and advertising paper — has fallen 21 percent in the past decade, according to the Pulp and Paper Products Council.
Kindles and iPads, email, PDFs, the decline of first-class mail, and waning newspaper and magazine circulations are all to blame.
Analysts predict demand will fall at least another 18 percent by 2024.
The shift is forcing paper mills and mill towns to rethink their future. To survive, they will need to find new products to make out of wood.
"We've got to go somewhere," said James Kent, the controller at UPM Blandin. "The world won't need paper forever."
Paper companies have tried to handle sinking demand for their product by cutting production.
Companies have closed 117 American mills since 2000, according to the Center for Paper Business and Industry Studies at Georgia Tech University.
Some 223,000 industry jobs have gone away in that time.
But demand is falling too fast for the cutbacks and consolidation to keep up.
Verso Paper, which closed the mill in Sartell after an explosion that killed a man and caused $50 million in damage, has never turned a real profit.
Created in 2006 when the private-equity firm Apollo Global Management broke off a division of International Paper. Verso has lost money every year but 2009.
That year, it got $239 million in federal tax credits for using a papermaking byproduct as an alternative fuel. If not for the explosion, the mill would have kept running for a time, but it had already shut down two machines and cut 175 jobs in late 2011.
When the mill closed permanently, leaving an additional 260 jobless, it was no surprise to the industry.
"The overall fact is demand is declining, and you could make a case that demand decline is going to accelerate going forward, so we're going to see even more shuts at a more rapid pace," said Paul Quinn, a paper- and forest-products analyst at RBC Capital Markets in Vancouver, B.C.
The foreign-owned paper mills in Minnesota — UPM Blandin and Sappi Fine Paper in Cloquet — are both working toward a future in which they produce something other than paper.
The companies, like their American counterparts, struggle against the overcapacity that plagues the industry. But they're trying to find new business models.
South African-owned Sappi is spending $170 million to convert its pulp mill to produce chemical cellulose that can be turned into thread for textile mills.
The Finnish parent company of the Blandin mill has invested in research of cellulosic nanomaterials, which chemists believe could be blended with other materials to make car and aircraft parts, and maybe body armor.
But the clock is ticking, and government efforts to prop up paper mills can only temporarily rearrange the industry.
In October, a mill in Nova Scotia abandoned by NewPage a year ago started back up under Canadian ownership, thanks in part to $125 million in provincial incentives. The paper industry in Maine cried foul at the subsidy because the mill can produce 360,000 tons of supercalendered paper each year.
U.S. mills got a gift during the recession when a favorable Internal Revenue Service ruling lavished them with $8 billion in federal tax credits for using "black liquor" — a byproduct of the papermaking process — as fuel. That's how Verso achieved its only profitable year. Quinn, the analyst, said Canada followed with a billion dollars in new energy-efficiency credits.
"All you're doing is you're moving around the mills," Quinn said.
"The reality is the demand is going down. Some mills are going to have to come out."


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Tagged: Euclides Rojas
7-24-11 PNC Park
Batting practice on a Sunday? It doesn't happen very often, but occasionally it happens.
My day began at 7:20 AM, as I woke up extra early so I could go to the gym before heading to the ballpark. I wanted to make sure that I had plenty of time with Amy as soon as batting practice ended.
Our due date is fast approaching. For fun, we offered our guesses on when our baby would be born. I picked July 26. Amy picked July 30th. The baby is due August 9. Neither of us think we'll make it that far as our baby is measuring up to be a big baby.
Anyhow, I stood on the bridge where I could see home plate. There was no cage.
I hung around for awhile longer, and at 11:05 AM, the cage was rolled out, so I immediately went into the stadium.
The Pirates came out and stretched, and at exactly 11:30, batting practice got underway.
My first ball came rather quickly – it was a clean catch of a homer caught here:
Realizing that there wouldn't be many home runs hit, (yesterday there were 3) – I made my way over to foul territory in right field and lined myself up behind the Cardinals pitchers, who had come out to warm up. There was virtually no one else around, as everyone stayed in left field trying to catch batted balls.
The strategy paid off as Trever Miller tossed me ball #2 on his way into the dugout,
and Raul Valdes tossed me ball #3.
Chris Resop saw me get ball #3 and glared at me in disapproval. Oh well.
For the last group, I went back to left field where I offered to glove trick a ball for a young fan. I had the ball in my glove when Euclides Rojas foiled the attempt by throwing his glove at mine, jarring the ball loose.
Rojas marched over and grabbed the ball, then something really weird happened.
He flipped me the ball.
It was the first time Rojas had ever acknowledged me, let alone toss me a ball.
Anyhow, true to my promise, immediately I handed the ball away to the young fan.
Batting practice had finished at noon, so I left too to be with Amy.
Game: 4 balls (1 hit, 3 thrown)
Season: 305 balls (131 hit, 67 thrown, 70 device, 37 found)
Games: 57 games
Career: 1,427 balls
Attendance : 35,402


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Taking the census in 1910 was just as difficult for census enumerators then as it is for today's census workers.
100 years ago today – Census Supervisor R.W. Hill issued an "ultimatum" that he would invoke "fines" and penalties if Seattle, WA residents continued to treat census takers with "discourtesy and contempt."
Click here to read the full story – 19 April 1910 – Seattle Daily Times.
You can read what was happening today in history or any day over the past 300+ years. GenealogyBank has over 4,300 newspapers online and adds more every day! Join now and start digging for your family history.
Read the stories of your ancestor's lives in the historical newspapers – see history as they lived it.
Click here to see a larger image of the 19 April 1910 Seattle Times front page.


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LeTourneau University's commencement speaker for the winter commencement ceremonies on the main campus in Longview will be William C. "Bill" Peel, executive director of LETU's Center for Faith and Work. Commencement ceremonies will begin at 10:30 a.m. Saturday, Dec. 15, at the S.E. Belcher Jr. Chapel and Performance Center at the Longview campus, 2100 S. Mobberly Ave. About 200 graduates from the traditional and working adult programs are expected to participate.
Peel has worked for the past 25 years helping people identify their calling and close the gap between Sunday faith and Monday work. He is an award-winning author of seven books (now in multiple languages). He served on the Promise Keepers' leadership training faculty and national speakers team. His book What God Does When Men Pray, a Silver Medallion Award winner, was Promise Keepers' first study guide and has sold more than 225,000 copies. With his friend Dr. Walt Larimore, Bill co-wrote the highly successful, Saline Solution, and the two taught healthcare professionals worldwide to effectively speak about faith issues with their patients. The men also co-authored Workplace Grace (formerly titled Going Public with Your Faith), winner of a Silver Medallion Award. His media appearances include repeat interviews on Focus on the Family, Moody Radio and numerous magazines.
He is also the founding pastor of Bethel Bible Church in Tyler, Texas, where he served from 1992 to 1997.
Peel earned his bachelor's degree is from Southern Methodist University, his Master of Theology from Dallas Theological Seminary, and he is currently pursuing doctoral studies at Gordon-Conwell Seminary. Bill and his wife, Kathy, have three grown sons and live in Dallas, Texas.
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- How much is my Russell worth?
The Museum does not appraise, evaluate, or authenticate works of art. To find an appraiser in your area, please contact the following resources:
- Where can I have my Russell authenticated?
- Bob Drummond, Coeur d'Alene Art Auction, Inc., 208.772.9009 (authentication and valuation)
- Gerald Peters Gallery, Santa Fe, NM, 505.954.5700
- Catalogue raisonné project: Charles M. Russell Center, University of Oklahoma, Norman, OK, 405.325.5937
- Public Collections and Libraries:
- Buffalo Bill Center of the West, Cody, Wyoming, 307.587.4771
- Gilcrease Museum, Tulsa, Oklahoma, 918.596.2700
- Montana Historical Society, Helena, Montana, 406.444.2694
- National Cowboy and Western Heritage Museum, Oklahoma City, Oklahoma, 405.478.2250
- Rockwell Museum, Corning, New York, 607.937.5386
- Sid Richardson Collection, Fort Worth, Texas, 817.332.6554
- What books do you have about Russell?
- Sample of Bibliographic Resources in the museum library's collection:
- Adams, Ramon F. Charles M. Russell, The Cowboy Artist. Pasadena: Trails End Publishing Company, 1948.
- Broder, Patricia. Bronzes of the American West. New York: H. N. Abrams, 1974.
- Dippie, Brian W. Remington & Russell: The Sid Richardson Collection. Austin: University of Texas Press, 1983.
- Hassrick, Peter J. Charles M. Russell. New York: Abrams, in Association with NMAA, Smithsonian Institution, 1989.
- Jennings, Kate F. Remington and Russell and the Art of the American West. New York: Smithmark, 1993.
- McCracken, Harold. The Charles M. Russell Book. Garden City, New York: Doubleday & CO., 1957.
- Paladin, Vivian A. Charles M. Russell: The Mackay Collection: An Illustrated Catalog. Helena: Montana Historical Society, 1979.
- Renner, Frederick. G. Charles M. Russell: Paintings, Drawings and Sculpture in the Amon G. Carter Collection. Austin: University of Texas Press, with the Amon Carter Museum, Fort Worth, 1966. Subsequent editions published by Harry N. Abrams, New York, 1966.
- Renner, Ginger. Charles M. Russell: The Frederick G. Renner Collection. Phoenix: Phoenix Art Museum, 1981.
- Renner, Ginger. A Limitless Sky: The Work of Charles M. Russell in the Collection of the Rockwell Museum. Corning, New York. Flagstaff, Arizona: Northland Press, 1986.
- Stewart, Rick. Charles M. Russell, Sculptor. Fort Worth: Amon Carter Museum; New York: Distributed by H. N. Abrams, 1993.
- Yost, Karl & Frederick G. Renner. A Bibliography of the Published Works of Charles M. Russell. Lincoln, Nebraska: University of Nebraska Press, 1971.
- Sample of Bibliographic Resources in the museum library's collection:
- I have a Russell painting from your museum. What is it worth?
In the past the museum sold reproductions on canvas of several popular paintings. These include two of Russell's works (In Without Knocking and Smoke of a .45). They were printed by Aaron Ashley in New York in two sizes. The reproductions were made on canvas and appeared to be original paintings. "Amon Carter Museum" was stamped on the back of each one. These reproductions are no longer for sale through the Museum Store, but many are still extant. Further, they have not appreciated in value from their original selling price.
- I have a Russell painting that I cannot find reproduced anywhere. How do I find more information on this work?
In partnership with the C. M. Russell Museum in Great Falls, Montana, the Russell Center at the University of Oklahoma is compiling a catalogue raisonné on Charles M. Russell. This ongoing project includes information on all of the artist's known oil and watercolor paintings, illustrated letters, pen and ink drawings, and original models.
- I have a Russell bronze. How can I tell if it's an original?
There are very few original Russell bronzes on the market. When available, they are usually sold by major galleries or auction houses. Russell authentication and valuations are done by some western art galleries. The museum receives many calls on reproductions of Russell bronzes. A popular one is a bronze figure of a mountain man on a horse fending off a mountain lion. This, we believe, is not Russell's work but that of another artist from the 1930s or 1940s. In addition, Russell's signature and buffalo skull mark do not necessarily signify authenticity.
- What foundry cast the Russell bronzes?
Roman Bronze Works, New York (see Museum Archives for information on the Roman Bronze Works Archives at the Amon Carter Museum); California Art Bronze Foundry, Los Angeles; Benjamin Zoppo Foundry, New York; Nelli Art Bronze Works, Los Angeles.
- Where do you find the foundry mark on the bronze?
Cast into the base, usually on the vertical edge at the back.
- Did Russell set his bronzes on a marble base?
No. However, reproductions are often sold on marble bases.
- Do you sell reproductions of Russell's bronzes?
No, but a handful of other museums do sell reproductions. Museums that sell bronze reproductions.
- I have a piece of pottery with a Russell picture and signature on it. Is it authentic?
There are only two known examples of Russell's painting on pottery (see Renner, Frederick. G. Charles M. Russell: Paintings, Drawings and Sculpture in the Amon G. Carter Collection. Austin: University of Texas Press, with the Amon Carter Museum, Fort Worth, 1966. (In subsequent editions published by Harry N. Abrams, New York, 1966, see p. 104.) Many of his most popular paintings and drawings have been reproduced on all types of media. Again, a Russell "signature" does not necessarily mean "authentic."


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High cholesterol can cause heart disease or a heart attack. Talk to your doctor about how often you need to get your cholesterol checked.
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Use these tips to start a conversation with a loved one about making heart healthy changes.
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Many people have questions for their doctors about tests, drug treatments, risk factors and lifestyle changes. These are examples of common questions.
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American Heart Association
Take this short quiz to learn how diet, physical activity, smoking and other factors impact the body's cholesterol levels.
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Coronary Artery Disease (CAD), or atherosclerosis, involves the hardening of the blood vessels by fatty deposits called plaque. Learn how you can lower your risk factors to improve your heart health. Spanish text is included in this document.
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Educational Institution — Click the resource link above to learn more
This site focuses on educating heart patients about the various aspects of coping with heart disease, including topics such as coping with depression, lifestyle changes, cholesterol and nutrition.
Mended Hearts, Inc.
Find out what your cholesterol numbers mean and what treatment your doctor may prescribe to help lower your cholesterol level. Includes a tool to estimate the risk for having a heart attack, and outlines ways to reduce risk through diet, exercise and drug treament.
Review Date: Tuesday, October 14, 2014
NIH National Heart, Lung, and Blood Institute - NHLBI
Red yeast rice, a traditional Chinese culinary and medicinal product, is marketed in the U.S. as a dietary supplement to help lower blood cholesterol levels. However, some red yeast rice products may not be safe, and may contain a potentially harmful contaminant.
Review Date: Thursday, April 02, 2015
NIH National Center for Complementary and Integrative Health - NCCIH
The lipid profile is a group of tests ordered together to determine your risk of coronary heart disease. These tests are good indicators of whether someone is likely to have a heart attack or stroke caused by blockage of blood vessels or hardening of the arteries (atherosclerois).
Review Date: Wednesday, November 25, 2015
American Association for Clinical Chemistry
Lowering your cholesterol may slow, reduce, or even stop the buildup of plaque in your arteries. It also may reduce the risk of plaque rupturing and causing dangerous blood clots. Learn about high and low-density lipoproteins (HDL and LDL), atherosclerosis, and more.
This easy-to-read booklet is designed to help you make the lifestyle changes that will lower blood cholesterol and reduce your risk for heart disease.
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Ben Henry aka Benry found himself the latest eliminated outcast on Survivor: Nicaragua after he was blindsided and sent packing.
In a new interview with TV Guide, the 24-year-old club promoter talks about being blindsided by Chase and his alliance, how his competitive nature might have led to his downfall and also touches on NaOnka Mixon and Kelly Shinn quiting the game. Excerpts from his interview below –
TVGuide.com: How surprised were you to get voted out?
Ben "Benry" Henry: It was a complete blindside. It was fun to watch with friends last night because nobody had any idea who was going home. … I think it was cool. It was an episode where people were on the edge of their seats and really up in the air as to what was going on. Personally, I did not see that coming. I was completely blindsided. I had no idea what was coming and I thought going into it that we were going to vote Fabio off. I thought that was the mutual consensus.
TVGuide.com: Do you think Chase's alliance chose to vote for you over Fabio because of how close you came to winning the immunity challenge?
Benry: Yeah, I think so. Definitely between Fabio or I, I think they looked at it and they really saw me as more of a physical threat and that I had been more of an asset to the tribe in pre-merge game … [They thought] I would have been a dangerous person to sit next to in the top three. I think they also thought Fabio is kind of dumb and would play along, so they sort of had him in their back pocket. They saw me as being a little more intelligent, a little bit more aware so I was the bigger threat.
TVGuide.com: At least you can say you gave it your all, unlike the quitters.
Benry: It's a bummer. They have no regrets, but if it were me, I wouldn't be able to sleep at night still. I heard a good quote the other day: "Quitters never win and winners never quit." … I think it's unfortunate that they pulled the plug with 11 days left, but it just goes to show that what kind of people they really are.
TVGuide.com: A lot of people are upset that they're still on the jury. What do you think about that?
Benry: There was definitely a lot of talk about that and I didn't think they would be allowed on the jury. There's really two sides to everything. Part of me says that they've been involved in the game and involved in conversations so their vote is somewhat valuable. Another part of me says that if there seven on the jury instead of nine then the vote still would have been there. I don't know.


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FREDERICTON - A former Liberal cabinet minister in New Brunswick has joined the provincial New Democrats and will lead the party's efforts to develop new policies.
In signing a party card on Thursday in Fredericton, Kelly Lamrock said he has no intention of running as a candidate in next year's provincial election.
Instead, Lamrock will help the party develop new policies and its election platform.
"I'm looking forward to running the platform process to show that we can be open and substantive and not just stay quiet and try to win the election by being a little less objectionable than the other guy," Lamrock said.
Lamrock was first elected in 2003 and was named to cabinet after the Liberals became the government in 2006. He served in the portfolios of education, social development and attorney general before being defeated in the 2010 election.
Lamrock said he wants to continue to contribute to politics but the Liberal party under new leader Brian Gallant is moving to the right.
"I didn't leave the Liberal party — the Liberal party chose to leave me," he said.
Gallant said Lamrock served the Liberal party well.
"We are happy to see his continued involvement in provincial politics, and wish him all the best in his future endeavours," Gallant said in a statement.
Lamrock said the New Democrats embrace the direction he wants to see, such as taking politics out of economic development and protecting social policies.
He will also be involved in the launch of a new website intended to explain NDP policies and seek input.
NDP Leader Dominic Cardy said he has been speaking to members of all parties and expects to have more people join his team before the next election.
"We have to build a unity party in New Brunswick that brings together Liberals, Conservatives, New Democrats and people from other parties who share a common commitment to wanting to lift kids out of poverty, making sure our government is run efficiently and effectively, and having the best run public service," he said.
The NDP have no seats in the legislature. The Progressive Conservatives have 41, the Liberals have 13 and there is one Independent.