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Megestrol (Megace®, Megace-ES®)
Pronounced: meh-JESS-trol
Classification: Progestational Agent
About: Megestrol (Megace®, Megace-ES®)
Megestrol is a man-made version of progesterone, which is a type of female hormone. This medication can be used to treat breast and uterine cancers. It is also used as a appetite stimulant for people with cachexia (muscle and weight loss or wasting and anorexia associated with cancer or AIDS).
How to Take Megestrol
Megestrol comes as a tablet, a suspension (liquid), and a concentrated suspension (Megace ES) to be taken by mouth. The dosage and schedule depend on which formulation you are taking and what it is being used to treat. Take megestrol at around the same time(s) every day.
Storage and Handling
Store this medication at room temperature in the original container. If you prefer to use a pillbox, discuss this with your oncology pharmacist. Ask your oncology team where to return any unused medication for disposal. Do not flush down the toilet or throw in the trash.
Where do I get this medication?
Depending on your prescription drug coverage, this medication may be available at a retail pharmacy or through specialty pharmacy. Your oncology team will work with your prescription drug plan to identify an in-network pharmacy for distribution of this medication via your local pharmacy or through a mail order specialty pharmacy.
Insurance Information
This medication may be covered under your prescription drug plan. Patient assistance may be available to qualifying individuals without prescription drug coverage. Your care team can help you access these resources, if they are available.
Possible Side Effects of Megestrol
There are a number of things you can do to manage the side effects of megestrol. Talk to your care team about these recommendations. They can help you decide what will work best for you. These are some of the most common or important side effects:
Fluid Retention
Swelling of the hands, feet, and ankles due to fluid retention is a common, but not harmful, side effect. Elevating the feet may help to lessen swelling in the feet and ankles. Avoid restrictive or tight clothing that may make it harder for the fluid to drain from the hands, feet and ankles.
Weight Gain
Weight gain as a result of increase in food intake is a common side effect of megestrol acetate, which is why it sometimes used to treat cachexia (muscle and weight loss or wasting and anorexia associated with cancer). This may be managed through dietary changes and exercise.
Blood Clots and Heart Attack
Megestrol can increase the risk of blood clots and heart attack. If you experience symptoms of these problems, you should contact your healthcare provider immediately or go to an emergency room. Symptoms can include: swelling, redness or pain in an extremity, chest pain or pressure, difficulty breathing, pain in your arm, back, neck or jaw, and shortness of breath.
Vaginal Bleeding
Women may experience light vaginal bleeding or spotting. Most commonly, this occurs when the medication is stopped. However, women who are already post-menopausal at the time they start megestrol acetate should report any vaginal bleeding to their oncologist, primary physician, or gynecologist.
Other Side Effects
Some people may experience nausea. This typically resolves after the first few weeks of therapy. Some people experience heartburn and/or gas. Talk with your care team if this becomes bothersome.
You may experience mood changes. These can include mood swings, anxiousness, restlessness or trouble sleeping.
If you have diabetes, your blood sugar may be higher than normal while on this medication. You may need to monitor your blood sugar more closely.
If you develop a rash, notify your care team as this can be a sign of a reaction to the medication.
This medication may make you less interested in sex. In men it may cause erectile dysfunction. Women may experience vaginal dryness.
Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Effective birth control is necessary during treatment, even if your menstrual cycle stops or you believe you are not producing sperm. You may want to consider sperm banking or egg harvesting if you may wish to have a child in the future. Discuss these options with your oncology team. You should not breastfeed while on this medication.


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Any dieter will confess that cravings are their downfall. You want something chewy, or sweet, or salty, or crunchy. And sometimes- you just have to give in.
Recently, an issue of US Magazine featured actress Eva Mendes saying that sometimes, she just has to have Pringles. I'm not sure which variety of the crave-worthy snacks she indulges in, but here is what Calorie-Count showed for a serving (14 chips) of the original Pringles:
– 160 calories
– 11 grams total fat, 3 grams saturated
– 1 gram protein
The nutritionist Joy Bauer suggested to Eva and other crunchy-cravers that they replace the Pringles and other chips with Glenny's Soy Chips. Actress Terri Hatcher of Desperate Housewives is a big fan, too! A 1.3oz bag of Glenny's Soy Chips has less of the bad stuff and more of the good stuff, like:
– 110 calories
– 2 grams fat
– 7 grams protein
Glenny's Soy Chips come in more than one dozen flavors- sure to satisfy anyone's craving, whether that be salt and pepper, sea salt, white cheddar, barbecue, caramel, cool ranch or even apple cinnamon.
Check out Glenny's for other healthier snack options like yummy little 100 calorie brownies, marshmallow treats and snack bars.


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filtered by Christian Formation, Finance, Discernment + 1 other(s)
By Mike Chalk
Every so often the leadership of a congregation decides that it is necessary to spend some valuable time discerning what needs to be addressed.
By Jerry Keucher
The Discernment phase of a capital campaign is as important as either the Feasibility Study or the Solicitation phase, and it is a unique part of ECF's capital campaign method.
By Linda Buskirk
In this time of returning back to ordinary activities, it is a good time to be asking why are we here?
By James Jordan
This webinar discussion will define transparency as it relates to churches, identify inhibitors to transparency, and enablers of transparency.
A social media content calendar example
By Sandra Montes
¡Las comunicaciones desempeñan un papel tan importante en la Iglesia! En el último par de meses, nuestro Obispo Presidente puso la rama episcopal del Movimiento de Jesús en el candelero. Han habido numerosos intentos de emplear la nueva fama del Obispo Curry para atraer gente a la iglesia: figuras de él en tamaño natural, camisetas, calcomanías, estandartes, etc.
By Sandra Montes
Are you involved in Spanish or bilingual church communications? In Jesus' Marketing Department, Sandra Montes speaks with four experts who work in Latino/Hispanic church communications, sharing their unique ministry challenges and what it means to communicate with this growing demographic in our Church.
By Nancy Cox Davidge
In last month's issue, Nancy Davidge argued that it is critical to shift our focus from 'what' to 'why' when we approach communications. In Thinking Strategically About Church Communications – Part 2, she takes us further, encouraging us to articulate the 'how' and 'who' – two important questions to ask when building a communications plan that is both strategic and effective.
By Kris Vieira
Pictures can tell powerful stories without relying on a single word. In Take Better Pictures For Social Media, Kris Vieira shares pointers to help you ramp up your visual communications skills and take photographs that truly resonate with your audience.
By Charis Bhagianathan
While church communication brings its own unique challenges, the best communicators are almost always excellent multitaskers. Meaningful communication involves planning, strategic thinking, a keen visual sense, creative writing and so much more. In this issue, we highlight resources from church communicators to help you plan, build and sustain your important work.
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Matt Dillon's character, Secret Service agent Ethan Burke will find a likeminded townie on Fox's limited series "Wayward Pines."
Juliette Lewis has been cast as Beverly, a local bartender who's also suspicious of "Wayward Pines," a Fox representative told TheWrap.
Beverly is described as "warm and approachable," though she doesn't mince words.
Also read: 'Mistresses' Star Shannyn Sossamon Joins Fox's 'WayWard Pines'
Lewis is best known for her many movie credits, including "What's Eating Gilbert Grape," "Natural Born Killers" and "From Dusk Till Dawn." But, she recently starred on the shortlived NBC series, "The Firm."
Aside from Dillon, she joins already announced cast members Shannyn Sossamon, Terrence Howard, Carla Gugino, Toby Jones and Melissa Leo on "Wayward Pines," which is based on Blake Crouch's novel series of the same the name.
The series, billed as "an intense, mind-bending thriller," follows Secret Service agent Ethan Burke (Dillon), who arrives in the bucolic town of Wayward Pines, Idaho, on a mission to find two missing federal agents. But instead of answers, Ethan's investigation only turns up more questions.
Also read: 'The Butler's' Terrence Howard Joins Fox Limited Series 'Wayward Pines'
M. Night Shyamalan directed the pilot and will executive produce the FX productions thriller along with writer/creator Chad Hodge, Donald De Line and Ashwin Rajan.
Lewis is represented by UTA, Troika and Untitled Entertainment.


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If you got excited over Oddworld: Stranger's Wrath HD's recent remaster and still haven't gotten enough Oddworld, you may be happy to hear that Oddworld: Munch's Oddysee HD has been confirmed via Just Add Water's Twitter to be coming by the end of Q2 for PS3 and PlayStation Vita.
Originally released as a launch title for the Xbox, Munch's Oddysee was the second chapter of the unfinished Oddworld pentalogy. I personally never got a chance to check it out because I was too distracted with Halo: Combat Evolved and Brute Force, so I'm definitely looking forward to giving it a shot. Just Add Water also released a comparison of Munch's old model with his new one and seeing just that improvement has me excited already. I'm a sucker for HD makeovers.
Oddworld: Munch's Oddysee HD coming Q2, see Munch's new model [Joystiq]
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Car Forums / Audi / Audi A4
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Meet your fellow owners in our Owners Clubs
Audi A4 Maintenance and Repair
catman0210 Posts: 2I had problems with the flasher unit/switch working intermittently. I took the switch out and stripped off the casing to look for broken circuit or anything obvious, and found that the unit worked if held at a certain position whilst still connected. I bent the terminals at the back just slightly and applied WD40 and it cured the problem. Cheaper that a switch! Could be worth a try.0
any progress on your issue. Mine did that and fianlly went out. checked the nossels and then the motor - everything seems to be fine. I believe it is the switch.. but have not opened this up yet.
AUDI A4 - 02 Wiper slowed down then went out. Checked motor which is fine. Suspect switch - anyone with similar experience - pls help. AD0
asaidi Posts: 1i also have a audia4-02 with a similar problem...
my blades we not stopped completely, they were stuck and went back and forth a slight bit , they would stop and flicker a little again ...thought maybe it was the fuse but it wasn't...we put some wd40 in the wiper connection bolt(unsure of the technical name) and it started to works again
i went to the dealer and they said it is a common problem and the part would need replacement at about $ 450
hope this helps0
brokencar Posts: 1I have an A4 convertible (3.0) Qt
i have had it for 4.5 years and have only done 21K miles.
the other day, the coolant was leaking. the garage have concluded that it is a crack in the short engine block. This is surely not down to wear and tear. Audi customer services are offering £1K towards a £7k bill. They do NOT accept it is a manufacturing fault, but will not tell me what caused it. Engine blocks do not just crack after 21K miles?
help would be greatly appreciated. Thank you.0
Depends on whether you allowed the car to overheat or not. If the crack (I assume in the cylinder bore) was due to a severe overheat, you'll have a hard time getting Audi to step up for that. If you can swear on ten holy books that the temp gauge never went into the red and that the overheat alarm didn't go off, then I'd raise hell with them. You might ask that a factory representative examine the block. These field engineers travel from dealer to dealer.0
My dealer just sent me an offer for an extended warranty on my 2005 Audi A4 convertible and it was about $4,600 for an extra 4 years or up to 100,000 miles. Though it seems like a lot to pay out at one time, I almost expect to pay out about $1,200 or more per year anyway once I'm out of the regular warranty and the car is over 4 years old. I expect to buy it, but don't know if there are competitive offers around.
It's offered bt Total Protection and is called "Supreme Coverage".
I'm generally satisfied with my car, though I just had a coolant leak at 36,000 miles and also had aaan ignition coil replaced after the 35,000 service.0
604doc Posts: 182It's probably negotiable. If you really want the warranty, offer him quite a bit less, and see what he says.0
jbird2412 Posts: 1Did you ever figure out a fix for that rattling coming from the drivers side door/under the dash area?? I just bought a 06 a4 and it has a rattle when going over rough pavement0
hauschild Posts: 62Guys,
2005.5 A4 - 35k miles - 2.0 Turbo Quattro
While on vacation this last week, I noticed the brake lights illuminating on the A4 as I walked out the door in the morning to take a ride. I found this severely odd - no light switches were turned on inside the vehicle and the car started, but barely. That day came and went without event.
However, a few days later as I attempted to take another drive, the battery was completely dead. I had my pops jump it and it started. The following evening, the battery was completely dead again. Had my pops jump again and the following morning it was completely dead once again.
So, I looked up the nearest Audi dealership in Wausau, Wisconsin and headed out for the nice 120 mile jaunt. Arrived mid-morning and explained the situation with the service manager. They couldn't find a problem after an hour messing around. I then let the manager know about the brakes lights being on that one morning. That was deal-sealer as the tech quickly found a faulty brake light switch.
My first question is why in the hell does a faulty brake light switch not cause some type of fault code??? I really found it odd that something as drastic as a piece of faulty circuitry that completely disables an engine can go unnoticed by the computer???
Anyhow, maybe this will help anybody that goes thru something like this in the future.
There was another thing I'd like some comments on. As I was talking with the service manager with the engine idling, he told me there is something wrong with my engine because it idles too loudly. I've never listened to an A4 engine, so I thought mine was normal. I was in a hurry that day to resume my vacation, so I told him I'd hold off until I return to Chicago, but he told me to definitely get it checked out because something's not right. Other than that, it runs good and I am getting around 34mpg's on my highway drives which is real good. Anybody have any concrete information on the engine that I can use before I make an appointment? I'm not sure a service manager would do much if I came in and said my engine was loud, ya know? Something specific would be appreciated.
robin25 Posts: 1My son's 2004 Audi A4 has Bose speakers and the front driver's side speaker seems to have blown. Can anyone tell me how I can go about getting it replaced other than to take it to the Audi dealer?0
huntzinger Posts: 356For a starting point, you might want to check out the website for Crutchfield, or find a hardcopy of their catalog. They offer aftermarket stereos and speakers for nearly all cars sold in the USA and as such, they have the info for "drop in" types of replacements.
Their website is
They used to have an affiliation with Discover Credit Card, which you might be able to save another 20% if you use part of your 'Cashback Bonus' for a gift card or whatever.
a6vos Posts: 1the motor may still be fuctional, but i would suggest to open up the motor and look at the gears inside, they may be worn.0
glenn15 Posts: 1Hi, This is my first question,any input welcome.I have a 1993 Audi 100 Avant,and
have a problem with the electric windows.when i first start the car the windows
do not operate,then after about 5mins they work ok,thie same thing happens every time i start the car,it also stops me closing the windows via the door lock.
Could the problem be the master switch?
pug3 Posts: 2Check Engine light stays on. What could be the problem?0
No way to know for sure without taking your car in to be checked out.
I'm aware that if the oxygen sensor goes bad for some reason, the check engine light comes on. At work this happens on the Malibu's in our fleet when the rodents chew on a wire when the car is parked in the lot overnight in the same space for a few days. For some reason, they go after the Malibu's and ignore the Stratus vehicles we have.0
mdstoloff Posts: 2Rich:
I had the same issue with my 06 A4 Avant. Traction light would come on an over-ride the engine. The dealer tried to fix the car several times but failed. Finally they said they placed an order for a new PC board that controlled the engine. They needed to get this direct from Audi in Germany and was made for my spacific vin number.... Worked like a charm. I have not had any issue since then.
Good Luck...
deepstar Posts: 15I have the same "problem" with my new 2008 Audi A4 2.0T Quattro. Lots of Slimey Black Soot in the exhaust. Makes a big mess trying to wipe down the tips. When it's wet...it splatters all over the back of the car. Why is this happening? This can't be good for my Catalytic's. Is anyone at Audi aware of this? I Went to the dealer...they told me I had "Bad Gas" and to refill with "Shell" Brand gas instead of the premium "BP" gas that I was currently using. I have never heard of this. This has to be a joke. I seem to be getting a lot of "Bad Gas" these days and it 's nothing Beano can fix!0
ilrndude Posts: 14deepstar,
They weren't joking about the "bad gas." Some brands have additives which will help prevent the very problem you describe. Brands such as Shell, Texaco, Chevron, and Conoco are good. Avoid Mobil/Exxon and BP. Google this issue about gas. It's not just Audis which are affected.
There should have been information provided when you bought your car. With the other owner material was included a list of good gas brands. I already knew about it and have been careful about the gas we put in our other car--a Saab.0
dowopdiddy Posts: 1I recently took my Audi to the dealer for the 40K scheduled maintenance. I have maintained this car regularly & have had no problems with the vehicle until AFTER the 40K maintenance.
Earlier this year, Audi sent me notice of a fuel pump recall. The dealer inspected the fuel pump & said it did not need replacing. They charged me $689 for the 40K & sent me off warning me that all the brakes had to be replaced within 3 months.
Then, two days later I had to return the car to the dealer when all the gas leaked out of the car as I was filling it up. The dealer ended up replacing the fuel pump after all even though they supposedly had just inspected it & found nothing wrong. But, even then, they tried to argue that they were not at fault! I argued my case & ended up with free rental car for the 4 days it took to order the pump & fix the problem that supposedly wasn't a problem.
Now, one week later, the engine light suddenly came on & the car abruptly started running rough - VERY rough. I managed to get the car back to my house although I was nervous driving it. Once again I called the dealer who then cited numerous possibilities (along with the cost for each possibility) such as a failed catalytic converter (cost = approx.$1,500). Of course the dealer failed to mention how the recent poor maintenance (incident #1 & #2) might be a factor.
I had no problems with this car until after this 40K scheduled maintenance. Then a host of problems cropped up. I have two questions based on the above: (1) Can I drive this car back to the dealer without worrying about engine damage or should I opt for getting it towed?; (2) What are the probable causes of ENGINE LIGHT ON + ROUGH ENGINE following a "heavy" maintenance?
Thanks so much for any help you can give to me.0
rowlandj Posts: 254It sounds like a bad coil-pack on your car. Typically on Audi's when they go bad it results in the behavior your seeing. This can be checked by a relatively simple scan tool at most auto parts stores. If the code shows a bad coil pack it may not show what cylinder but there are ways to determine which relativaly easily.
If you do a searc on the web for "audi coil pack diy" you'll likely find the best method.
Your car is just about the right age and mileage for this to happen and it's not uncommon at all. Just poor timing.
PS - that dealer sounds like a nightmare, you may do better finding a good independent shop in the area that specializes in German vehicles VW/Audi in particular. There are lots of them out there.0
It was a rough engine after replacing the spark plugs in my case. It ended up that they needed to replace an engine coil - probably same as mentioned in another reply. they told me this sometimes happens after replacing a spark plug. Driving the car should be OK if it's just a small distance to the dealer.0
tyler13 Posts: 1I just bought a 1999 A4 quattro this morning and the power windows quit working for me! They worked on my way to lunch but when i got back into the car they didn't work at all. the sunroof doesn't work now either. It still works to open and close them with the key in the door lock but thats it. Any idea's as to what the cause of this might be?0
vapor6969 Posts: 3can anyone tell me if my release bearing and lever are bad do i need to replace the whole clutch kit0
This is a duplicate question which has been addressed already in the "Transmission Traumas" topic.0
Hard to say. First thing I'd do is see if a scanner will pick up a trouble code to help with the diagnosis. Of course, I'd also get out your owner's manual and check any fuse related to these operations.
ALSO - in your "8-way Relay Carrier" there is a module that we must hold under suspicion, given its function:
Relay # 4 Power Window / Sunroof Control Module0
antonio2012 Posts: 4hello, how you doing?
i have an audi a4 2.8 v6 quattro 1998 automatic triptronic.
the problem is when i go like in 3 or 4 gear, the car start to shake a little bit (no matter if the car is in automatic or with the triptronic).
The slippage occurs in either of two situations: 1) during slight acceleration (feathering-in the gas pedal) on upward inclines without initiating a downshift (which I consider an engine lugging situation), and 2) during slight acceleration immediately after deceleration at 50-60 mph range. The slippage does not occur hard acceleration. No fault lights (red or yellow) are lit and VAG-COM scanning shows no DTC faults in any controller.
Someone told me that it was a faulty torque convertor, i want to know where i can buy that part over the internet. Or if someone can tell me how i can fix this problem.
sfaudi Posts: 1Hey there, I've got a 1998 A4 Quatro, and the right rear window is stuck all the way down. I know it's probably the motor, but is there a way to manually roll up the window before I can get it serviced? Please reply asap!!! Thanx!0
10sfan Posts: 136Looking to purchase a used 2007 A4 Quattro with 6,000 miles, not Certified. Concerned with difference in gas milage and if certification. current warranty expires in four years and will never exceed that 50,000K. Appreciate any comments.0
lizzie6 Posts: 1can any one tell me how 2 access relay indicator0


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Yes, sugar is still the leading culprits – and genetics, diet, immunity, oral hygiene, susceptibility, and fluoride exposure play roles. But a large and growing body of research suggests that oral decay is also an infectious disease. Cavities in Hilliard are a major issue with children.
There have been numerous studies that have found cavity causing bacteria can be passed from the primary caregiver to infants and toddlers during a period where the children's immune systems have not been fully developed. This places young children at a higher risk of cavities. This is called vertical transmission and is most likely with those who have severe or untreated tooth decay.
Recently it has been shown that bacteria can also be passed among siblings and classmates. This is known as horizontal transmission. To our Hilliard neighbors, it can be very difficult to understand what is best for our children when it comes to oral hygiene. But it is difficult to quantify what degree these vertical or horizontal transmissions are responsible for cavities.
A 2000 study published in the Journal community dentistry and oral epidemiology found that young children with high levels of chief cavity causing bacteria are five times more likely to have tooth decay than those with lower levels.
A certain amount of these bacteria are normal in the mouth. But when young children begin to get an overwhelming inoculation of the bacteria before they are able to fend them off with their immune systems, the bacteria can colonize more effectively putting them at a higher risk of cavities.
And then when excessive sugars are present in the child's diet, it fuels even more bacterial growth. This allows them to reach harmful numbers. If the bacteria are not properly brushed from the teeth, tongue and pallet, they can build up and create plaque. Plaque is essentially food debris that turns into acid.
Cavities are nothing more than a chemical equation. You have enamel that is very hard. But if you throw enough acidic plaque on it, it will begin to decompose. It is important to understand the role of bacterial transmission and tooth decay in young children. This has led to an enormous effort by professional dental organizations to educate parents. Even general need to see children at the early age of one, or at least when their first teeth emerge.
There are some dentists who don't always follow these guidelines, of getting a child in at an early age to check the teeth. The problem is that many people are not aware of the direct link between the health of baby teeth and long-term oral health in adults. Even when baby teeth fall out these bacteria continue to flourish. When cavity causing bacteria are left unchecked in people who have serious decay, the bacteria continues to grow and teeth can even begin to fall out.
There are many things a parent can do to help a child keep a healthy mouth. Call Infinite Smiles dentistry in Hilliard Ohio today to set up a consultation with Dr. Neal Patel. You will find them very helpful. The education you were will receive will be invaluable for the future health of your child's oral hygiene.
Call 740 – 881 – 2600 today for consultation.


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You are encouraged to file the Free Application for Federal Student Aid (FAFSA) via the web at http://www.fafsa.ed.gov.
Each student and at least one parent should apply for an FSA ID.
Go to http://www.fafsa.ed.gov and complete the FAFSA. Central College's FAFSA school code is 001850.
The FAFSA is a FREE service. You should not pay to complete the form.
Online processing time for the FAFSA takes 2-3 business days. The Department of Education will notify you that your application has been processed and will provide you with a Student Aid Report (SAR).
Students who are Iowa residents need to file the FAFSA by July 1 to be eligible for Iowa Tuition Grant. Note that your form must be received at the processor (not simply mailed) by this date.
Central College can assist you in filing the FAFSA. Contact Wayne Dille at 641-628-5336 or Donna Newendorp at 641-628-5187 for assistance. Also visit "Seven Easy Steps to the FAFSA" for additional tips.


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Saturday, February 19, 2011
I Stayed Up Late to Listen to GeneaBloggers Blog Talk Radio
I have been on mailing lists and am on Facebook an GenealogyWise, but had never participated in any kind of "chat" before. Yes, it was a bit chaotic, but people were actually exchanging information like mad! Perhaps things were especially lively because everyone was talking about (and perhaps some had already participated in?) Donna Pointkouski's "WDYTYA Drinking Game."
The call-in part of the show is very enjoyable - it is great to hear the actual voices of people with whom you have corresponded or whom you recognize from the genealogy world. DearMyrtle was a fantastic substitute host, juggling the phone-ins with the chat conversations, and Thomas MacEntee even called in at one point.
There were many different "sub-conversations." In one of them, Lisa Alzo and I (and a couple of others) were putting out ideas for Linda Robbins for researching her husband's uncle, Jozef Marion Jurkiewicz.
I missed the first 45 minutes of the show, but during the time I was listening, the number of people connected to chat was in the 60s and 70s.
The URL is http://www.blogtalkradio.com/geneabloggers. This is a great way to socialize with your fellow genealogy bloggers even if you cannot travel to conferences and other events. For those of us in the East, the show is on from 10:00 to 12:00 p.m. on Fridays.
7 comments:
Me 2, Me 2! It is such a whirlwind of excitement and fun. Best 2 hours of the week!ReplyDelete
Me 3, Me 3.ReplyDelete
Me addicted!
Thanks Greta for your support of GeneaBloggers Radio! I am having so much fun with it and I was glad to see so many folks on the chat board Friday night!ReplyDelete
I couldn't stay up late, but I'm glad you had lots of fun. The two previous weeks, I attended, so I know what you are talking about. Maybe we can reach 100 this Friday, wouldn't that be fun...see or hear you then.ReplyDelete
Sheri, Carol, and Barbara - I am really looking forward to this Friday - a "social event" I can attend in my jammies!ReplyDelete
And Thomas - Thank you so much for coming up with this. I hope it continues after the WDYTYA season winds up!
How very neat! I didn't even know it existed-but think it's way cool : )ReplyDelete
I do have to say, it still needs a little "polish," but I'm done listening to it by Saturday night (if I don't catch it "live"), so... :-)ReplyDelete


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Latest media releases
Results of UBS AG's Annual General Meeting
At the Annual General Meeting on April 28, 2011, UBS shareholders reelected the members of the Board of Directors, with Joseph Yam being newly elected to the Board. The Annual General Meeting was attended by 2,077 shareholders, representing 1,520,014,923 votes.
Basel, 28 April 2011 - At the Annual General Meeting on April 28, 2011, UBS AG's shareholders approved the Annual Report and Group Financial Statements for 2010 and reaffirmed Ernst & Young Ltd., Basel, as auditors.
In a consultative vote, shareholders ratified the 2010 Compensation Report with 64.40% of the vote. They also granted discharge to the members of the Board of Directors and the Group Executive Board for 2010 (97.82%).
Elections to the Board of Directors
At the Annual General Meeting, the following Board members were reelected: Kaspar Villiger (96.96%), Michel Demaré (98.99%), David Sidwell (98.87%), Rainer-Marc Frey (98.12%), Bruno Gehrig (91.70%), Ann F. Godbehere (98.87%), Axel P. Lehmann (98.98%), Wolfgang Mayrhuber (91.12%), Helmut Panke (91.23%) and William G. Parrett (98.85%). Joseph Yam (98.69%) was newly elected to the Board.
Kaspar Villiger retains his position as Chairman of the Board of Directors, Michel Demaré as Vice Chairman and David Sidwell as Senior Independent Director, as intended by the Board members in the event of their reelection.
Detailed CVs of all the members of the Board of Directors are available at www.ubs.com/bod.
Media Contacts
Switzerland +41-44-234 85 00


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In hiring programmers, a common test is the Fizz Buzz test. What are some neat/interesting variations on fizz buzz which keep with about the same difficulty level?
Basically, if I asked someone to do a fizz buzz test over email or something, I'd want to make sure they can't just google the code.


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Seasoned cruisers who have already gone island-hopping in the Caribbean, explored the shores of the Mediterranean and ventured deep into the Alaskan wilderness can prepare for their next global adventure to remote archipelagos and lesser-known ports. Bring home a treasure trove of new memories and stories when you sail with Crystal Cruises, your key to the world's most fascinating locales amidst ultimate luxury.
We'll help you be among the first to discover the little-explored beauty of the Seychelles aboard the all-new Crystal Esprit. With 115 granite-and-coral islands scattered jewel-like across the Indian Ocean, the Seychelles, a seemingly far-flung locale, is within easy reach with Crystal Cruises' first all-inclusive super-yacht.
Brace yourself for an unforgettable journey through the North Atlantic from Reykjavík to Portsmouth including a maiden call in Iceland as well as a visit to the rugged Faroe Islands and Scotland's western isles.
From the pre-Inca ruins of Peru to the carved-rock city of Petra, epic voyages allow you to combine sailing to far-off locales with restful days at sea.


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Location and Hours
From Annual 2008
Exhibit Hours and Location
The exhibits will be held June 28-July 1, 2008, at the Anaheim Convention Center, located at 800 West Katella Avenue in Anaheim.
Exhibit Hours are:
Saturday, June 28-Monday, June 30 - 9:00 am - 5:00 pm
Tuesday, July 1 - 8:00 am - 12:00 pm
Please Note: Wheeled carts are not allowed on the exhibit floor. This includes carts, briefcases with wheels - any wheeled cart or bag that must be pushed or pulled. Strollers are allowed ONLY if there is a child in them at all times.


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New 2020 HyundaiElantra SEL Sedan
- Stock: HY7129
- Exterior Color
- Silver
- Interior Color
- Black
- Body/Seating
- Sedan/5 seats
- Transmission
- continuously variable automatic
- Drivetrain
- front-wheel
- Engine
- 2.0L I-4 cyl
Hyundai Elantra
Highlighted Features
- Blind spot sensor
- Lane departure
- Automatic temperature control
- Wireless phone connectivity
- Exterior parking camera rear
- Front dual zone A/C
- Split folding rear seat
- Remote keyless entry
Detailed Specifications
Dealer Notes
2020 Hyundai Elantra Silver SEL 2.0L 4-Cylinder FWD IVT
KBB.com Consumer Reviews
- 5.0
Love this car!
By Jacky D. on Monday, May 14, 2018I feel like Im driving a 40,000.00 car! The SEL has all the comforts of a luxury sedan for half the price! This car moves so smoothly and quietly and the gas mileage is unbelievable.
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Some people think that the 3DS' new second-circle-pad add-on is ugly. They mock it. They deride it. But maybe the 3DS "slide pad" is a beautiful homage to one of history's greatest video game box-art optical illusions.
You see a slide pad.
I see Pierce Brosnan's extended jowl on the cover of Nintendo 64 classic GoldenEye.
See? See how the cheek sticks out on Bond's face? It's really his fist, but you get the idea. Now look at that slide pad again. Same thing. Sorta.
Bravo, Nintendo. Excellent homage. Can we now officially call this add-on the 3DS Jowl?
(Yes, yes, we're having much fun with Nintendo and their slide pad today, but once I thought of this resemblance, I couldn't unthink it. Had to share.)
You can contact Stephen Totilo, the author of this post, at email@example.com. You can also find him on Twitter, Facebook, and lurking around our #tips page.


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The IPCC, Elvis and the elephant in the room
Everywhere you go in Berlin there are nostalgic echoes of the past - in the shadow of the wall's remnants, old Trabants take tourists on nostalgic car rides to times long gone.
And at the conference centre where IPCC delegates have been ensconced for a week deliberating on how to save the world from dangerous climate change, other ghostly voices have been making their presence felt.
Every night at the Estrel, Elvis lives. And so does Marilyn Monroe.
For the location is best known as the home of musical impersonators, the walls festooned with posters showing the capes, medallions and curled lips of the men who would be King.
In this slightly surreal atmosphere, the more sober suited ladies and gentlemen of the IPCC finalised a plan to end the world's addiction to carbon.
But their report clearly echoed the sentiments of the Memphis legend.
"A little less conversation, a little more action please..."
The world can tackle climate change said the leaders of this working group on mitigation: it is not rocket science, it is mostly economics.
Their Summary for Policymakers pointed out that investments in renewables needed to triple, subsidies to fossil fuels needed to decline and a switch to natural gas could help wean countries off coal.
Window of opportunity
But timing - in music, comedy and climate science - is everything.
The report's authors say there is a double-glazed window of opportunity that is rapidly closing.
If the world embraces low-emissions energy sources on a huge scale before 2030, the carbon curve can be bent in our favour.
If we don't act in time, we'll be trying to concoct some scheme to suck the CO2 out of the air and bury it in the ground.
The big changes being proposed by the IPCC can be done for what seems a bargain price of a 0.06% reduction in consumption growth every year until the end of the century.
"Statistically you won't notice," said Dr Ryer Gerlagh, who was a co-ordinating lead author on the economics chapter of this report.
"Developing countries may grow not by 5% per year, but 4.9%; in the UK you may not grow by 2% a year but 1.9% instead. There won't be any statistician who would be able to make the difference between the two."
'Huge pain'
So has the IPCC discovered a painless path to a carbon-free nirvana down in the jungle room?
Not quite.
"There will be huge pain. We will have to change our energy supply systems. That may not cost us a lot of income, but we will have to think about windmills, solar panels - major changes. It is going to be tough," said Dr Gerlagh.
Fossil fuels will only have a future with technologies that capture their carbon. Many greens are unhappy with these concepts, believing that they're the devil in disguise.
Whatever the merits of the technologies, we just can't take the risk and we have to find a way to insure ourselves against the worst, says Dr Gerlagh.
"We should pay a risk premium, not because we are definitely certain the world is going to end, but we don't like the risk of playing with the Earth. We've got only one."
Who will pay?
While everyone is looking to the challenges ahead, some other participants here have been looking wistfully at the past, and not just because of Marilyn or Elvis.
Some of the delegates were concerned that the past emissions that got the world into this climate mess seem to have been forgotten about.
"Countries are developing in different ways. There are some changes in their emissions patterns, but there are also historical emissions we have to take onboard," said Dr Yacob Mulugetta from the University of Surrey, another of the report's authors.
"The key question is how do you bring in the past emissions and align them with the future?"
This question seems to have sparked some of the same divisions between the developed and developing world that have hampered the UN climate negotiation process.
The scientists appear to have agreed on the causes, impacts and solutions to the climate challenge, but there are divisions appearing about who should cut, and who should pay. As we get clarity on the medicine, people begin to worry about the bill.
"They see the elephant from different angles," said Dr Mulugetta, "and it poses its challenges."


text:
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Cruiser Bike
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text:
MatchPoint is a next generation CP generator. The result of a GSoC2007 projectSoC2007_project_Feature_Descriptor, it is still very experimental. Experience reports needed. Read more here
Integral images
Before detection process images are integrated. Each element-pixel (x,y) of integral image represents sum of pixels from (0,0) to (x,y) on initial image. This makes calculating sum of a region much faster. In addition, convolution at any scale has equal time complexity. This part is neccessary only when using box filters for detection.
Feature detection
Points are detected with Hessian Detector using box filters. Here is a description of detection process over time. This may not be entirely compatible flow with the algorithm's flow, because some parts are simultaneous(e.q. first two steps).
Convolution of pixels
Convolution of a pixel at certain scale is carried out with approximation of Gauss 2D function - this is called box filter detection. Each kernel has 4 convolution filters(3 of them are unique - xy and yx filters are the same). The resulting value is then the determinant of Hessian matrix where elements represent convolution values of 4 filters.
Kernel sizes for convolution are:
9,15,21,27, (1st octave)
15,27,39,51, (2nd octave)
21,45,69,93 (3rd octave)
MatchPoint features also offers two ways of convolution:
- box filter: faster and preferable way
- sliding window(implemented for convinience but needs debug): slower, more accurate but also more sensitive to noise
Finding maxima
In order to achieve invariance to scaling, detection needs to find maxima of Hessian determinant across many scales. To handle this, octaves were introduced. Octaves are interpolation of determinants at various scales(usually two scales). MatchPoint offers detection at max 3 octaves(by setting a parameter). E.q. at first octave a point can be detected at scale 1.6(=((9+15/2)*1.2)/9 where 1.2 is initial scale and 9 is initial kernel size) or 3.2(=((21+27/2)*1.2)/9. Keypoint's main scale is then selected according to the highest value of Hessian determinant.
Selecting points
Next step is to select points with high values of their determinants(regardless of scale where points where detected) that represent invariant keypoints that will be used further processing. This is achieved using a fixed threshold which should be set low(because otherwise it may happen that no points would be detected).
Then non-maxima supression is applied(only points with local maxima of determinants are selected).
At this point we have a list of points that can vary in length, because threshold from previous step is hardcoded. This can result in over 200.000 points for larger images and that is too much(regardless of image size we need the same amount of control points for all images - min 3 control point/overlapping images), so we need to strip down the list below 10.000 points(this number is set intuitivelly and it is based on consumed time). (Note: this work is progress).


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The rain held off for those who gathered at Grove Hill Cemetery Monday to pay tribute to the nation's and the county's war dead.
Col. Roger Green, local VFW commander, who organized the event, noted the appropriateness of the cemetery as a site for the ceremony.
"Every section of this cemetery has a veteran in it," Green said.
The featured speaker was Col. Ron Turner with the Army National Guard, who praised America's war on terrorism.
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Home / Texas Educators / Preparation and Continuing Education / Consumer Information
Approved educator preparation programs (EPPs) annually provide the Texas Education Agency and State Board for Educator Certification information about their programs as mandated in Texas Education Code Section 21.0452. This information is posted below to assist individuals interested in obtaining a teaching certificate to select the educator preparation program that best meets their needs. This information is also useful for school districts planning their staffing and recruitment activities.
Additional information on approved educator preparation programs including locations and types of certificate programs offered can be found on the Division of Educator Standards' list of approved programs and the individual program websites. The Educator Preparation Programs Technology Curriculum webpage
is a published list of EPP webpage links.
This page serves as a resource for persons seeking information concerning
activities offered by EPPs related to technology integration, and/or technology
curriculum and instruction.
Annual educator preparation program reports are brief, 3-page documents that provide a comprehensive view of each Texas educator preparation program, including accreditation and consumer information data, in accordance with Texas Education Code 21.0452.
2017-2018 ASEP Annual Reports
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Accreditation ratings for EPPs are linked below:
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Compliance reports for educator preparation assure that each Educator Preparation program (EPP) is held accountable for compliance with the Texas Administrative Code Chapter 229 for certification of candidates completing the programs.
Program certification passed tests results for various EPPs are linked below:
ASEP Reports MenuInitial Pass Rates Menu
Reports with the results of the survey by EPP are linked below:
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Federally mandated Title II state reports are available below:
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Redemption feels good.
Earlier in the season, the Bisons Track & Field team competed at our in-town SEC foe, Vanderbilt. Many of us did well.
But I did not.
I had just come back from spending spring break on a mission trip, and I was exhausted. I threw my absolute worst performance ever, but this last weekend we went back to Vanderbilt, and I had the chance to redeem myself. Like I said, it felt good.
This weekend was fun because it was our second in-city meet in a row. We had competed at TSU the week before. It is always nice to be close enough that our friends can actually come out and support us. We had a wonderful turn out from so many of our Lipscomb athletics family: volleyball, soccer, basketball, some tennis, and others.
We had a ton of support from just the Lipscomb student body as well. And we demonstrated just how much better we can perform when everyone is just going bonkers cheering for us.
We had so many wonderful performances by our Track & Field athletes this weekend. Tucker Peabody won both the 100m and the 200m dashes. His 200 was good enough to set him up as the seventh fastest man in the nation in that particular event.
No big deal, or anything, right? Lipscomb's track program is quickly growing into one of the best in the nation. We had several other podium performances from our athletes, and much of our success was due to the support given to us by our Lipscomb family.
Being an athlete at Lipscomb means that you are a member of several families. The first family is your actual family back home (wherever that is for you). The second family is the entire herd of Bisons that attend classes at Lipscomb University. The third family is our team.
It can be difficult balancing all of the responsibilities that come with being an active member of each of these families, but everyone knows that athletes love a good challenge.
Another good thing about competing at Vanderbilt is that many of our team members have real family close enough to Nashville to make the trip and actually see us compete. It's an extra pressure placed upon you to perform well when your family name is put on the line with your performance, and your family is there to either watch you succeed or crumble under the weight of competition. I love it!
Unfortunately, for much of our team members this week, we had a misunderstanding with team rules and the appropriate value placed on the scales we use to balance out our different families.
Our team competes much better when we have people cheering for us. That is just a fact. This weekend, due to a misunderstanding, some left parts of the meet early to attend family dinners or hangout with friends. This unfortunately left many of our teammates without a cheering section. They still performed well, and we were very proud of their results, but doing better is always better.
The misunderstanding wasn't intentional by any of us. We had received an email earlier in the week that said people did not have to show up to the meet until their event, which led us to believe that we were also free to leave since it seemed that the cheering this week was going to be dialed down due to late arrivals.
However, this was not the case. Just because everyone was not required to show up for the morning events, did not grant us amnesty for leaving early. It was something that many athletes just did not take into account as the finished athletes left in mass exodus as some athletes were just arriving. It seemed fair and logical, but that's not what matters.
The thing that matters is stepping up. We are supposed to transcend fair and logical. And we are supposed to do it, not because our coaches force us to, but because we genuinely want to be better teammates than any team out there. When we reach that point, which I honestly think that we have, we will then need to use ourselves as points of reference. We must step up and out perform ourselves to better our abilities as teammates.
It takes an introverted perspective to continue building a team that is already the best at something. In order to reach higher, we must attempt to outshine each other on our team.
If someone does not show up to cheer for us, then we clearly must cheer for them, because that is how our team will continue to grow. There are clearly times when the track family has a much heftier value than our real family.
Even if we see our teammates and coaches everyday and it's been a few months since we've seen our real family, as athletes, we are called to make these sacrifices for our team. We must put aside the love for our family even though they drove for hours to spend time with us and see us compete.
We are called to support our track family who missed our own performances, because this track family is our lifeblood in college. We are just so dependent on each other for success.
As I say all of the time" `We are Bisons'. As Bisons, we must remain strong, loving, and loyal to each other. Bisons always run in a herd, and that is how we will operate from now on.
We have just a few weeks left before conference, and if we are going to stand any chance of winning against the more heavily-favored teams, these sacrifices are clearly ones we have to make to get right.
Here we go LU. Go Bisons.
Redemption feels good.


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Sardinian, LogudoresePrint
Primary tabs
500,000 (Salminen 1993).
Sardinia region: generally south of Sassari town.
6b (Threatened). Statutory language of provincial identity in central Sardinia (1999, Atlantic Coast Languages Act No. 162, Article 4).
Barbaricino, Northern Logudorese, Nuorese, Southwestern Logudorese. No one form of Sardinian is selected as standard for literary purposes. Logudorese is different from other Sardinian varieties. Lexical similarity: 68% with standard Italian [ita], 73% with Sassarese [sdc] and Cagliare dialect of Sardinian, Campidanese [sro], 70% with Gallurese [sdn]. Sardinian has 85% lexical similarity with Italian, 80% with French [fra], 78% with Portuguese [por], 76% with Spanish [spa], 74% with Romanian [ron] and Ladin [lld]. A member of macrolanguage Sardinian [srd].
Latin script [Latn].


text:
SAN DIEGO and DUBLIN, Jan. 27, 2012 /PRNewswire/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Alkermes plc (Nasdaq: ALKS) today announced that the U.S. Food and Drug Administration (FDA) has approved BYDUREON™ (exenatide extended-release for injectable suspension) – the first once-weekly treatment for type 2 diabetes. BYDUREON is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes in multiple clinical settings. BYDUREON will be available in pharmacies nationwide in February.
To view the multimedia assets associated with this release, please visit: http://www.multivu.com/mnr/53897-amylin-alkermes-plc-bydureon-fda-approved-treatment-type-2-diabetes
"With BYDUREON, U.S. physicians and patients can now choose a therapy that offers continuous blood sugar control in just one dose per week," said John Buse, M.D., Ph.D., professor of medicine, director of the Diabetes Care Center and chief of the Division of Endocrinology at the University of North Carolina School of Medicine in Chapel Hill. "New treatment options are essential for the millions of adults with type 2 diabetes who continue to struggle to achieve optimal blood sugar control."
The approval of BYDUREON (pronounced by-DUR-ee-on) was based on safety and efficacy data from the DURATION clinical trial program, in which treatment with BYDUREON resulted in improvements in glycemic control with just one dose per week. The approval was also based on clinical experience with BYETTA® (exenatide) injection, a twice-daily form of exenatide that has been available in the U.S. since June 2005 and is used in nearly 80 countries worldwide. BYDUREON uses Alkermes' proprietary technology for long-acting medications to provide a controlled release of exenatide.
"As the first and only once-weekly diabetes treatment, BYDUREON represents an important milestone in Amylin's promise to bring to market innovative therapies to help improve the lives of people with type 2 diabetes," said Daniel M. Bradbury, president and chief executive officer, Amylin Pharmaceuticals. "BYDUREON builds upon the proven benefits of BYETTA, offering significant improvements in glycemic control in a single weekly dose."
In the DURATION-5 head-to-head clinical study, after 24 weeks of treatment, patients taking once-weekly BYDUREON experienced a statistically superior reduction in A1C of 1.6 percentage points from baseline, compared to a reduction of 0.9 percentage points for patients taking BYETTA. A1C is a measure of average blood sugar over three months. Both treatment groups achieved statistically significant weight loss by the end of the study, with an average loss of 5.1 pounds for patients taking BYDUREON and 3.0 pounds for patients taking BYETTA (weight loss was a secondary endpoint).The most frequently reported adverse event in both groups was nausea, reported less frequently by BYDUREON users (14 percent) than by BYETTA users (35 percent). Other common treatment-emergent adverse events in the BYDUREON group included diarrhea, upper respiratory tract infection and injection site nodules. There were no major hypoglycemic events.
BYDUREON has been approved with a Risk Evaluation and Mitigation Strategy (REMS) to ensure that the benefits of BYDUREON outweigh the risk of acute pancreatitis and the potential risk of medullary thyroid carcinoma. As part of the REMS, Amylin has established a communication plan for healthcare professionals to help minimize these risks. In addition, Amylin will fulfill a number of post-marketing requirements to further assess the impact of BYDUREON on medullary thyroid cancer and cardiovascular disease. More information will be available at www.BYDUREON.com.
BYDUREON is provided in a straightforward single-dose tray so that patients can self-administer the once-weekly subcutaneous injection. In the DURATION clinical studies, the delivery system was well accepted by patients and physicians.
Amylin to Host Investor Conference CallAmylin will host a conference call led by Mr. Bradbury to discuss the approval of BYDUREON today at 4:30 p.m. EST. A slide presentation accompanying the conference call will be made available through the "Investors" section of Amylin's corporate website at www.amylin.com.
The call will be webcast live through the "Investors" section of Amylin's corporate website, and a recording will be made available following the close of the call. To access the webcast, please log on to www.amylin.com approximately 15 minutes prior to the call to register, download and install any necessary audio software. For those without access to the Internet, the live call may be accessed by phone by calling (800) 857-5738 (U.S./Canada) or (415) 228-4970 (international), conference access code #7253303. A replay of the call will also be available by phone beginning approximately two hours after the close of the call and can be accessed at (800) 964-3620 (U.S./Canada) or (203) 369-3425 (international).
About BYDUREON™ (exenatide extended-release for injectable suspension)BYDUREON, previously known as exenatide once weekly, is the first and only once-weekly medicine to be approved by the FDA for the treatment of type 2 diabetes. BYDUREON works with the body to help make its own insulin when needed, providing continuous glycemic control with just one dose per week. Each dose of BYDUREON is made up of biodegradable microspheres that provide a controlled release of exenatide throughout the week.
BYDUREON is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes mellitus, and should be used along with diet and exercise. BYDUREON is not recommended as the first medication to treat diabetes.
BYDUREON is a long-acting form of the medication in BYETTA® (exenatide) injection so both drugs should not be used together. BYDUREON is not insulin and should not be taken instead of insulin. BYDUREON is not for people with type 1 diabetes or people with diabetic ketoacidosis. BYDUREON is not recommended for use in children. It is not known if BYDUREON is safe and effective in people with a history of pancreatitis or severe kidney problems. See important safety information below. Additional information about BYDUREON will be available at www.BYDUREON.com.
Important Safety Information for BYDUREON™ (exenatide extended-release for injectable suspension)
In animal studies, BYDUREON caused rats to develop tumors of the thyroid gland. Some tumors were cancers. It is not known if BYDUREON causes thyroid tumors or a type of thyroid cancer called medullary thyroid cancer (MTC) in people. BYDUREON should not be used if there is a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2.
Based on post-marketing data, exenatide has been associated with acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis. Patients should be observed for signs and symptoms of pancreatitis after initiation of BYDUREON.
The risk of getting low blood sugar is higher if BYDUREON is taken with another medicine that can cause low blood sugar, such as a sulfonylurea. The dose of sulfonylurea may need to be lowered while BYDUREON is used. BYDUREON should not be used in people who have or had severe kidney problems and may cause or worsen problems with kidney function, including kidney failure. Patients should talk with their healthcare provider if they have severe problems with their stomach, such as delayed emptying of the stomach (gastroparesis) or problems with digesting food. Antibodies may develop with use of BYDUREON, which may lead to worsening or failure to achieve adequate glycemic control. Severe allergic reactions can happen with BYDUREON. There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with BYDUREON or any other antidiabetic drug.
The most common side effects with BYDUREON include nausea, diarrhea, headache, vomiting, constipation, itching at injection site, a small bump (nodule) at the injection site, and indigestion. Nausea most commonly happens when first starting BYDUREON, but may become less over time.
These are not all the side effects from use of BYDUREON. A healthcare provider should be consulted about any side effect that is bothersome or does not go away.
For additional important safety information about BYDUREON, please see the full Prescribing Information (www.BYDUREON.com/pi) and Medication Guide (www.BYDUREON.com/mg), to be posted shortly.
About BYETTA® (exenatide) injectionBYETTA was the first glucagon-like peptide-1 (GLP-1) receptor agonist to be approved by the FDA for the treatment of type 2 diabetes. BYETTA exhibits many of the same effects as the human incretin hormone GLP-1. GLP-1 improves blood sugar after food intake through multiple effects that work in concert on the stomach, liver, pancreas and brain.
BYETTA is an injectable prescription medicine that may improve blood sugar (glucose) control in adults with type 2 diabetes mellitus, when used with a diet and exercise program. It can also be used with metformin, a sulfonylurea, a thiazolidinedione or Lantus® (insulin glargine), which is a long-acting insulin.
BYETTA is not insulin and should not be taken instead of insulin. BYETTA should not be taken with short- and/or rapid-acting insulin. BYETTA is not for people with type 1 diabetes or people with diabetic ketoacidosis. BYETTA has not been studied in patients with a history of pancreatitis. Other antidiabetic therapies should be considered for these patients.
BYETTA provides sustained A1C control with potential weight loss (BYETTA is not a weight-loss product). BYETTA was approved in the U.S. in April 2005 and in Europe in November 2006 and has been used by more than 1.8 million patients since its introduction. See important safety information below. Additional information about BYETTA is available at www.BYETTA.com.
Important Safety Information for BYETTA® (exenatide) injection
Based on post-marketing data, BYETTA has been associated with acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis. Patients should be observed for signs and symptoms of pancreatitis after initiation or dose escalation of BYETTA.
The risk of getting low blood sugar is higher if BYETTA is taken with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. The dose of sulfonylurea or insulin may need to be lowered while BYETTA is used. BYETTA should not be used in people who have severe kidney problems and may cause or worsen problems with kidney function, including kidney failure. Patients should talk with their healthcare provider if they have severe problems with their stomach, such as delayed emptying of the stomach (gastroparesis) or problems with digesting food. Antibodies may develop with use of BYETTA. Patients who develop high titers to exenatide could have worsening or failure to achieve adequate glycemic control. Severe allergic reactions can happen with BYETTA. There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with BYETTA or any other antidiabetic drug.
The most common side effects with BYETTA include nausea, vomiting, diarrhea, feeling jittery, dizziness, headache, acid stomach, constipation and weakness. Nausea most commonly happens when first starting BYETTA, but may become less over time.
These are not all the side effects from use of BYETTA. A healthcare provider should be consulted about any side effect that is bothersome or does not go away.
For additional important safety information about BYETTA, please see the full Prescribing Information (www.BYETTA.com/pi) and Medication Guide (www.BYETTA.com/mg).
About DiabetesDiabetes affects nearly 26 million people in the U.S. and an estimated 347 million adults worldwide.[i],[ii] Approximately 90-95 percent of those affected have type 2 diabetes. In the U.S., diabetes costs more than $174 billion per year in direct and indirect medical expenses.[iii]
According to the Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey, approximately 60 percent of people with diabetes do not achieve their target blood sugar levels with their current treatment regimen.[iv] In addition, 85 percent of type 2 diabetes patients are overweight and 55 percent are considered obese.[v] Data indicate that weight loss (even a modest amount) supports patients in their efforts to achieve and sustain glycemic control.[vi],[vii]
About Amylin PharmaceuticalsAmylin Pharmaceuticals is a biopharmaceutical company dedicated to improving lives of patients through the discovery, development and commercialization of innovative medicines. Amylin is committed to delivering novel therapies that transform the way diabetes, obesity and related metabolic disorders are treated. Amylin is headquartered in San Diego, Calif. and has a commercial manufacturing facility in Ohio. More information about Amylin Pharmaceuticals is available at www.amylin.com.
About Alkermes plc Alkermes plc is a fully integrated, global biopharmaceutical company that applies its scientific expertise and proprietary technologies to develop innovative medicines that improve patient outcomes. The company has a diversified portfolio of more than 20 commercial drug products and a substantial clinical pipeline of product candidates that address central nervous system (CNS) disorders such as addiction, schizophrenia and depression. Headquartered in Dublin, Ireland, Alkermes plc has an R&D center in Waltham, Mass. and manufacturing facilities in Athlone, Ireland; Gainesville, Ga.; and Wilmington, Ohio. For more information, please visit Alkermes' website at www.alkermes.com.
Forward-Looking StatementThis press release contains forward-looking statements about Amylin and Alkermes. Actual results could differ materially from those discussed or implied in this press release due to a number of risks and uncertainties, including the risk that BYETTA and/or BYDUREON and the revenues generated from these products may be affected by competition; unexpected new data; safety and technical issues; clinical trials not being completed in a timely manner, not confirming previous results, not being predictive of real-world use or not achieving the intended clinical endpoints; label expansion requests or New Drug Application filings not being submitted and/or accepted in a timely manner or receiving regulatory approval; the commercial launch of BYDUREON in the U.S. being delayed or not successful; or manufacturing and supply issues. The potential for BYETTA and/or BYDUREON may also be affected by government and commercial reimbursement and pricing decisions, the pace of market acceptance, or scientific, regulatory and other issues and risks inherent in the development and commercialization of pharmaceutical products. These and additional risks and uncertainties are described more fully in Amylin's and Alkermes' SEC filings including their Quarterly Reports on Form 10-Q and Annual Reports on Form 10-K. Amylin and Alkermes undertake no duty to update these forward-looking statements.
BYETTA is a registered trademark and BYDUREON is a trademark of Amylin Pharmaceuticals, Inc. All other marks are the marks of their respective owners.
[i] Diabetes Statistics. American Diabetes Association. Available at: http://www.diabetes.org/diabetes-basics/diabetes-statistics/. Accessed January 19, 2012.
[ii] Danaei G, Finucane MM, Lu Y, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet. 2011;DOI:10.1016/S0140-6736(11)60679-X.
[iii] Direct and Indirect Costs of Diabetes in the United States. American Diabetes Association. Available at: http://www.diabetes.org/how-to-help/action/resources/cost-of-diabetes.html. Accessed January 19, 2012.
[iv] Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA. 2004;291:335-42.
[v] Bays HE, Chapman RH, Grandy S. The relationship of body mass index to diabetes mellitus, hypertension and dyslipidaemia: comparison of data from two national surveys. Int J Clin Pract. 2007;61:737-47.
[vi] Nutrition Recommendations and Interventions for Diabetes: a position statement of the American Diabetes Association. Diabetes Care. 2008;31 Suppl 1;S61-78.
[vii] Anderson JW, Kendall CW, Jenkins DJ. Importance of weight management in type 2 diabetes: review with meta-analysis of clinical studies. J Am Coll Nutr. 2003;22:331-9.
(Logo: http://photos.prnewswire.com/prnh/20120126/MM42834LOGO)
SOURCE Amylin Pharmaceuticals
Amylin - Alice Izzo, +1-858-642-7272, Cell: +1-858-232-9072, firstname.lastname@example.com; Alkermes - Rebecca Peterson, +1-781-609-6378, Cell: +1-617-899-2447, email@example.com


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$1.09 – $4.37
Cert Org
$4.37/ kg
Cert Organic
De-Cert Org
$5.50/ kg
Hawkes Bay Produce
Napier Produce
...is providing the freshest & most nutricious Organic food, at low cost prices. Minimising toxic pesticides, chemicals & hormones which is vital for babies & children to develop while enabling families to achieve optimum health.
A large portion of the fresh produce is locally grown from Franklins very own dedicated Organic growers.
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Nearly every construction job requires a ladder or step stool of some kind. Even if all you are doing is changing a light bulb, you need to be able to reach it. Filling simple construction needs like having the right size ladder can make any job quicker and easier so it's a good idea to make sure you have a variety of step stools and ladders handy before you start any construction job and Sam's Club has great prices on all types and sizes of step stools and ladders.
It's also a good idea to have safety equipment on hand before you begin any construction or repair job. Of all the construction needs, this one is the most important as you always want to make sure you protect yourself against possible injury while you work. Wearing proper eye protection, ear protection, face masks and back supports all help insure that you will complete the work safely and without serious injury.
Sam's Club is the best place to go for all your construction needs whether your job is big or small. Being sure you have the right equipment and safety gear before you start will make all the difference when it comes to completing a home repair or construction job quickly, correctly and safely.


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ReversaL 72559 | After Effects Template | Free Download
Short description
Show your logo and text message in this modern, elegant, 3D and classy opener/closer. This project is made in FullHD 1920×1080 but it can be easily resized to HD 1280×720. ReversaL is great opener for trailer promos, video productions, presentations, product showcases, portfolios and more.
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Additional informtaion
Font used in the comp is free one and it can be found here: http://www.dafont.com/champagne-limousines.font
ReversaL is placed in 3d studio made in AE with simulation of shadows, no pre-rendered elements. You can also change the colors of everything, lines, background, speeds, duration etc. Sounds are not included but if you like them send me a PM. Feel free to contact me anytime if you find difficult to customize this template and I'll try to help you as much as I can. Thank you for your time and don't forget to rate.
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169 Riverside Drive, Binghamton, NY 13905
Phone: 607-798-5111 • 800-227-2345
Lourdes Hospital is proud to be home to the Southern New York American Cancer Society (ACS) Resource Room, the first ACS Resource Room in upstate New York.
The ACS Resource Room offers a variety of information to newly diagnosed cancer patients, their families, and support persons. All available pamphlets, booklets, and brochures are free and include information about various types of cancer.
Trained volunteers, who are also Lourdes Hospital volunteers, staff the Resource Room. Volunteers can assist patients with finding information about a particular type of cancer, assist with wig and hat fittings, and offer referrals to the ACS for free patient programs and services available in their community. Wigs and hats are also available at the ACS Office at 13 Beech Street, Johnson City.
Because the ACS Resource Room is staffed by volunteers, hours of operation may vary. Typically, the ACS Resource Room is open for at least three hours daily between the hours of 9:00 AM and 4:00 PM.


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For Immediate Release
Will Matthews, ACLU, (212) 549-2582 or 2666; firstname.lastname@example.com
Terri Sharpley, SPLC, (334) 956-8311; email@example.com
Groundbreaking Federal Consent Decree Will Prohibit Solitary Confinement of Youth in Mississippi
Children Will No Longer Be Housed in Facility Run by Private Prison Company After ACLU and Southern Poverty Law Center Lawsuit
JACKSON, Miss. - Children under the supervision of the Mississippi Department of Corrections (MDOC) will no longer be housed in a privately run prison or subjected to brutal solitary confinement under the terms of a groundbreaking settlement of a federal class-action lawsuit filed by the American Civil Liberties Union and the Southern Poverty Law Center (SPLC).
The lawsuit charged that conditions at the Walnut Grove Youth Correctional Facility, operated by GEO Group, Inc., the nation's second largest private prison corporation and which houses youth convicted as adults, are unconstitutional.
"This represents a sea change in the way MDOC will treat children in its custody," said Sheila Bedi, deputy legal director for SPLC. "As a result of this litigation, Mississippi's children will no longer languish in an abusive, privately operated prison that profits each time a young man is tried as an adult and ends up behind bars."
Under the proposed decree, MDOC will be required to remove the youth from the GEO-operated prison and house them at a standalone facility, governed by juvenile justice rather than adult standards. MDOC will be required to provide the youth with a broad variety of rehabilitative services and strong protections from sexual abuse and violence. The decree also categorically bars the state from subjecting young people to solitary confinement - the first time a federal court has banned the barbaric practice of housing children in long-term isolation.
"It's been known for a long time that prolonged solitary confinement causes terrible suffering and psychiatric breakdown even in mature healthy adults - let alone in emotionally vulnerable children and teenagers," said Margaret Winter, associate director of the ACLU National Prison Project. "Getting these kids out of the greedy hands of GEO is a big step forward, and the ban on solitary confinement in this decree is truly unprecedented."
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The lawsuit, filed in November 2010 by the ACLU, SPLC, and civil rights attorney Robert B. McDuff, challenged notoriously abusive conditions in the GEO-run facility. The lawsuit describes the routine practice of GEO staff peddling drugs to the teenagers in their custody, subjecting them to brutal beatings, sexual exploitation, solitary confinement and failing to protect them from violence at the hands of older, predatory prisoners. One youth suffered permanent brain damage as a result of an attack in which GEO staffers were complicit.
The consent decree will also require MDOC to protect the adults who will be housed at Walnut Grove from physical and sexual abuse, violence, excessive use of force and prolonged isolation, and will require MDOC to increase its oversight of GEO.
The hearing to finalize the decree is scheduled for March 22 at 9:00 am in the courtroom of U.S. District Court Judge Carlton Reeve in Jackson.
A copy of the settlement agreement is available online at: www.aclu.org/prisoners-rights-racial-justice/cb-et-al-v-walnut-grove-correctional-authority-et-al-consent-decree
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1-2 C. of any 3 of these things:
Sliced Almonds, Sliced Cashews, Sunflower Seeds, Sliced Coconut, Sesame Seeds (or whatever you want:)
¾ C. Olive Oil
¾ C. Honey
¾ C. Maple Syrup
½ t. vanilla
½ t. salt
Preheat oven to 275 degrees. Mix dry ingredients in a large bowl and set aside. Blend wet ingredients and salt in a blender and pour over dry ingredients. Mix and spread out over 2 large cookies sheets. Cook at 275 for 15 minutes. Stir, cook another 15 minutes. Continue for ~1.5 hours. Freezes well.


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I have a really good recipe for whipped vanilla frosting that I want to use, but I want to make a chocolate frosting. What kind of chocolate should I add to the frosting to make it a chocolate frosting? How much should I add? Should I reduce the amount of vanilla in the recipe or keep it the same?
How should I modify my vanilla frosting to convert it into a chocolate frosting? [closed]
closed as not a real question by Mien, KatieK, SAJ14SAJ, TFD, kiamlaluno Jan 16 '13 at 0:35
It's difficult to tell what is being asked here. This question is ambiguous, vague, incomplete, overly broad, or rhetorical and cannot be reasonably answered in its current form. For help clarifying this question so that it can be reopened, visit the help center. If this question can be reworded to fit the rules in the help center, please edit the question.
3It depends. You may wish to provide your base recipe to get some advise. However, any addition of chocolate is going to change the ratios in the frosting, because you are adding fat (cocoa butter, with its own unique melting charactaristics) as well as cooca solids and sugar; if you are adding cocoa, it is quite dry, and also astringent which will change the recipe. You are probably far better off finding a stellar chocolate frosting recipe that you like. You might want to google "whipped ganache" for some ideas. – SAJ14SAJ Dec 31 '12 at 2:08
Whatever your type frosting is, ie Italian meringue or confectioners' frosting, you can simply add enough (cooled) melted chocolate or cocoa powder (sifted to remove lumps) until it tastes good to you. Since neither cocoa powder nor melted chocolate will curdle the frosting it is simply a matter of taste. However, if you are going to refrigerate the frosting, remember that the chocolate will solidify and thus your frosting will become firmer.
For some rough guidelines I recommend 1/4 cup cocoa powder for every 2 cups of frosting and 3 ounces melted chocolate for every cup of frosting.
Use a good quality dark chocolate, with a high proportion of cocoa solids, for a strong chocolatey taste. Or, if you don't like dark chocolate, use a half and half mixture of milk and dark chocolate.
Real chocolate would just be diluted by the sugar/butter in your frosting recipe. You can use it (as much as you want), but I suspect you will be underwhelmed if you do. With the price of chocolate these days, you'll probably be disappointed with the outcome.
Cocoa powder is what you want. Add 1 tablespoon at a time until you reach the desired flavor profile.
If you want big chocolate flavor, consider a chocolate ganache (or other form of nearly-pure chocolate frosting.)
Marcel Desaulniers Death by Chocolate has plenty of recipes that won't let you down (but will cost a lot of money).


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Haven't registered a client license in quite a while and don't remember all the particulars. We have a client that needs to move their license to a new box. Where do I find the licensing file that I have to move, together with the program. Is it part of the OCX? Does anyone know what the file name is?
Actually, once I find out, I probably want to keep copies of those license files for all our clients in a folder on my system, so I can accommodate them in the future, when they want to move a license, etc. Does anyone see any problem with it?