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TEACH Campaign
Grant Awards
An Attainable Dream
Student Aid Rules
Practice Guides
Odds and Ends
Quote to Note
Upcoming Events
TEACH Campaign
On September 27, during a live broadcast as part of NBC's Education Nation Summit, Secretary Duncan launched a national teacher recruitment campaign. The campaign features a web siteTeach.govdedicated to providing information and resources for students and prospective teachers, including an interactive "pathway to teaching" tool designed to help individuals chart their course to becoming a teacher. The campaign also features public service announcements (PSAs) by celebrities, members of the Administration, and local leaders celebrating our country's teachers and urging today's students to teach. "With more than a million teachers expected to retire within the coming years, we have a historic opportunity to transform public education in America, by calling on a new generation to join those already in the classroom," the Secretary emphasized. "We are working with the broader community to strengthen and elevate the entire teaching profession, so that every teacher has the support and training they need to succeed."
The campaign has several goals:
- increasing the number, quality, and diversity of people seeking to become teachers, particularly in high-need schools (both urban and rural) and subject areas in greatest demand (math, science, technology, English language learners, and special education);
- connecting aspiring teachers with information about the pathways to teaching, including preparation, certification, training, and mentoring; and
- celebrating and honoring the profession of teaching.
Moving forward, the Department will be working with Facebook on an interactive application that will connect experienced teachers with young people. And, the Department will be collaborating with Ebony magazine on a series of teaching roundtables across the nation. "Education is the great equalizer in America," the Secretary stressed. "If you care about promoting opportunity and reducing inequality, the classroom is truly the place to start. Great teaching is about so much more than education." (Note: Video of the Secretary's session with NBC News' Tom Brokaw is available online.)
Also: During an Education Nation Summit interview with TODAY's Matt Lauer, President Obama called for a longer school day and year.
Grant Awards
Prior to the end of the federal fiscal year (September 30), Secretary Duncan announced grants under three key programs, including the Department's remaining American Recovery and Reinvestment Act (ARRA) programs. First, he announced 49 Investing in Innovation (i3) Fund grants, representing a cross-section of school districts and non-profit organizations (such as institutions of higher education) from among nearly 1,700 applicants under the $650 million program. i3 supports local efforts to start or expand innovative, research-based programs that help improve outcomes for high-need students and close the achievement gap. The Administration has requested $500 million in funding for i3 in Fiscal Year 2011. Next, the Secretary announced 21 Promise Neighborhood planning grants, representing a diverse set of communities in major metropolitan areas, small- and medium-sized cities, rural areas, and an Indian reservation. This initiative supports cradle-to-career services that improve the academic achievement and healthy development of children. The Administration has requested $210 million in funding for Promise Neighborhoods in FY 2011: $200 million for implementation grants and $10 million for new planning grants. Then, the Secretary announced 62 Teacher Incentive Fund (TIF) grants, representing various states, districts, and non-profit organizations from 27 states. TIF seeks to strengthen the education profession by rewarding excellence, attracting teachers and principals to high-need and hard-to-staff areas, and providing educators with the feedback and support they need to succeed. The Administration is awarding the first two years of funding$442 millionwith further funding of the five-year grants contingent on Congressional action.
Meanwhile, the Department has also awarded new grants for charter schools, magnet schools, preventing youth substance abuse and violence, school counseling, smaller learning communities and dropout prevention, community resource centers and special education parenting centers, emergency management for higher education, Hispanic-Serving Institutions, and American Indian Colleges and Universities.
An Attainable Dream
Last month, the Department released a new video produced especially for Spanish-speaking families that shows how going to college is more attainable and affordable than ever. This five-minute piece profiles Samantha Hernandez, a sophomore at California State University (CSU) at Dominguez Hills, and shows the support she receives in pursuit of her academic and career goals. Her story is told in her own words, as well as those of her fellow students, faculty advisor, college president, and family membersin Spanish. The camera follows Hernandez on campus and at home in South Central Los Angeles. The release of this video coincided with the signing by President Obama of a proclamation commemorating National Hispanic-Serving Institutions (HSIs) Week.
Also: Both the opening and closing plenary sessions of the October 5 White House Summit on Community Colleges will be streamed live on WhiteHouse.gov. The opening session begins at 12:15 p.m. ET, and the closing session begins at 3:00 p.m. ET. In the coming days, the White House will issue a toolkit about the content and the structure of the summit.
Student Aid Rules
The Department is on schedule to implement new regulations to strengthen federal student aid programs. The regulations will be released in phases. Final regulations to ensure program integrity are scheduled for publication on or around November 1, 2010, and will go into effect on July 1, 2011. These regulations will address sections of the agency's gainful employment proposal for the for-profit education sector, as well as 13 other issues, in an effort to protect students from aggressive or misleading recruiting practices and offer consumers better information about the effectiveness of career college and training programs. Final regulations on the remaining portions of the gainful employment proposal, dealing with a program's eligibility to receive federal student aid, are scheduled for publication in early 2011. These regulations were originally scheduled to be published on or around November 1, 2010, but the Department is taking additional time to consider the comments received and to host several meetings and public hearings in the coming weeks. These gatherings will allow interested parties to clarify the comments they have submitted and respond to questions from Department officials, while permitting the regulations to go into effect on or around July 1, 2012.
Practice Guides
The What Works Clearinghouse has issued two new practice guides, with practical recommendations for educators to help them address the challenges they face in their classrooms and schools. "Improving Reading Comprehension in Kindergarten Through Third-Grade" recommends five specific steps that teachers, reading coaches, and principals can take to improve reading comprehension for young readers: teach students how to use reading comprehension strategies; teach students to identify and use the text's organizational structure to comprehend, learn, and remember content; guide students through focused, high-quality discussion on the meaning of text; select texts to support comprehension development; and establish an engaging and motivating context within which to teach reading comprehension. "Developing Effective Fractions Instruction for Kindergarten Through Eighth-Grade" recommends five strategies to help educators improve students' understanding of fractions: build on students' informal understanding of sharing and proportionality to develop initial faction concepts; help students recognize that fractions are numbers and that they expand the number system beyond whole numbers; help students understand why procedures for computations with fractions make sense; develop students' conceptual understanding of the strategies for solving ratio, rate, and proportion problems before exposing them to cross-multiplication as a procedure to use to solve such problems; and set a priority on improving teachers' understanding of fractions and how to teach them. Each practice guide recommendation includes a summary of supporting research, implementation strategies, and potential roadblocks and solutions. What Works is an initiative of the Institute of Education Sciences (IES).
Odds and Ends
Last week, the White House Office of Faith-Based and Neighborhood Partnerships teamed up with the Department and the Corporation for National and Community Service to host a Convening on the Role of Community-Based Organizations in Turning Around Low-Performing Schools. A select group of participants discussed how to strengthen partnerships between school districts, schools, and community-based organizations. The group also identified promising ways that community and interfaith service initiatives can help transform schools through academics, youth development, health and social supports, and family engagement.
This week, President Obama announced a new goal of recruiting 10,000 science, technology, engineering, and math (STEM) teachers during the next two years.
For Constitution Day (September 17), Secretary Duncan joined HistoryMakers, civil rights leaders, and educators at Dorothy Height Community Public Charter School in Washington, D.C.
September 20 and 21, the Department held the "Sustainability Education Summit: Citizenship and Pathways for a Green Economy." Approximately 300 participants discussed ideas and proposals for a national agenda to advance a sustainable economy through education. Congress requested that the Department organize the summit in the Higher Education Opportunity Act.
For National GEAR UP Day (September 29), the Secretary visited Friendship Public Charter School in Washington, D.C., and connected via video to active projects in North Carolina, Pennsylvania, and Texas.
According to a new report jointly requested by the presidents of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine, the outlook for America's ability to compete for quality jobs in the global economy has continued to deteriorate the last five years, and the nation needs a sustained investment in education and basic research to keep from slipping further.
Sixteen members of the President's Advisory Council on Asian Americans and Pacific Islanders were recently sworn-in during a special ceremony at the U.S. Capitol.
The National Archives has launched a new online tool for teaching with documents. Not only does DocsTeach.org welcome educators to explore thousands of documents in a variety of media from the holdings of the National Archives, but it also allows teachers to combine these materials using clever tools to create engaging activities. Teachers can create lessons from scratch, adapt lessons from others, or let their students create the lessons, and a single suite of tools can be applied to a range of subjects and skill levels.
Quote to Note
"I know we've gone through a tough time these last two years. I do worry sometimes that young folks, having grown up or come of age in difficult economic times, start feeling as if their horizons have to be lowered, and they've got to set their sights a little bit lower than their parents or their grandparents. I just want to remind people that you guys all have enormous challenges that you're going to have to face, but you live in the most vibrant, most dynamic, wealthiest nation on Earth. If you are able to work together as a generation to tackle long-standing problems that you inherited but that are solvable, then there's no reason why the 21st century is not going to be the American Century, like the 20th century was. And, there's still billions of people around the world who want to come here, and they want to come here because they know that this isfor all our problemsstill the land of opportunity."
|President Barack Obama (9/27/10), on a conference call with college and university student journalists
Upcoming Events
On October 21, Lights On Afterschool!, a coast-to-coast rally organized by the Afterschool Alliance, will illuminate the nation by celebrating afterschool programs and the need they meet in keeping students safe, helping working families, and improving academic achievement. This year, 7,500 afterschool programs, including many of the Department-funded 21st Century Community Learning Centers, will host activities.
Over the next two weeks, the Department will exhibit at or sent materials to the Family Friendly Schools' Engage! All Families Conference in Las Vegas (October 6-7), the National Indian Education Association's Annual Convention in San Diego (October 7-10), the Division for Early Childhood's Annual Conference on Young Children with Special Needs and Their Families in Kansas City, Missouri (October 14-17), and the National Rural Education Association's Annual Convention in Branson, Missouri (October 15-17). If you are attending any of these events, please stop by the Department's booth or pick-up materials.
Credits, Subscribe & Unsubscribe
Please feel free to contact the Office of Communications and Outreach with any questions:
Director, Intergovernmental AffairsStacey Jordan, (202) 401-0026, email@example.com
Program AnalystAdam Honeysett, (202) 401-3003, email@example.com
To be added or removed from distribution, or submit comments (we welcome your feedback!), please contact Adam Honeysett. Or, visit http://www2.ed.gov/news/newsletters/edreview/index.html.
This newsletter contains hypertext links to information created and maintained by other public and private organizations. These links are provided for the user's convenience. The U.S. Department of Education does not control or guarantee the accuracy, relevance, timeliness, or completeness of this outside information. Furthermore, the inclusion of links is not intended to reflect their importance, nor is it intended to endorse any views expressed, or products or services offered, on these sites, or the organizations sponsoring the sites.


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Wallet Card
Wallet Card (Word document)
A pocket reference for dealing with law enforcement
TES Fest 2008
Susan Wright of NCSF held the positions of Public Relations Director and Media Spokesperson for TES Fest 08, a 700-person weekend event over the 2008 July 4th weekend hosted at the Radisson Hotel in Piscataway NJ. This TES event, like the previous one, had the challenge of establishing a working relationship with a new venue and a new town. Susan continued to be a great ambassador for us as she met with the hotel, police and fire departments and did a spectacular job with helping us to forge a new set of relationships. She also, along with her vast resources at NCSF, helped research all relevant laws in the new town we were in to ensure that our event was in total legal compliance. In particular, she also performed admirably at-event in interfacing with the local law enforcement personnel which we hired as auxiliary security staff. We owe Susan a hearty "Thank You" for a series of 4 TES Fest's that were trouble free!
Director, TES Association
Executive Director, TES Fest 08
Consent Counts Mission Statement
Mission: To decriminalize consensual BDSM (Bondage, Discipline, Dominance/submission, sadomasochism) in U.S. law by ensuring that consent will be recognized as a defense to criminal charges brought under assault laws and other statutes.
Unlike most other sexual issues (rape, for example), BDSM activities—a "scene", a dungeon party, a Dominant/submissive or Master/slave relationship—can result in a criminal prosecution and conviction even where the activity is entirely consensual. It's important to remember that most BDSM activities are treated as violence and not sex. This is not speculation; in 2010, NCSF's incident response help line received 204 requests for help concerning criminal prosecutions.
NCSF's research of cases throughout the United States revealed that not a single appellate court decision has allowed consent as a defense to a BDSM-based criminal prosecution for assault, sexual abuse, etc. Even where a state law allows the consent defense in cases that do not involve "serious bodily injury," appellate courts have ruled that the use of nipple clamps or hot wax produces "serious bodily injury".
The realization that our communities are at risk of criminal prosecution led to the launch of the "Consent Counts" initiative in 2006 at a Leather Leadership Roundtable at NGLTF's Creating Change. At this Roundtable and one held subsequently at the Leather Leadership Conference, decriminalization of consensual BDSM was determined to be the number one priority of the BDSM/Leather/Fetish communities. It was subsequently determined that NCSF would take a leadership and coordinating role. This is, with the related initiative to change the way BDSM is viewed by psychiatry in the DSM criteria, NCSF's most important project.
Our "Consent Counts" initiative is multi-faceted. We have researched the statutes, court decisions and relevant law review articles in all 50 states, and the results of that research are available on the NCSF website. We are presenting programs and holding meetings with our communities across the country, to build understanding of the issues and to develop consensus on an effective approach to nationwide activism. A national discussion guide has been created to facilitate local discussions to assist in the drafting of a community-wide statement on consent at LLC at Seattle 2013 with the goal of decriminalization and to promote local and national activism. This aspect of our initiative also includes an EOP focused on Frequently Asked Questions about the criminal law issues and on Best Practices by which individuals and groups can reduce the likelihood of prosecution and—equally important—enable us to argue more effectively that what we do is mutually pleasurable erotic activity (not violence) and
that care is taken to ensure consensuality and avoid excessive stimulation or unintended harm. In addition, NCSF has published primers for both alleged victims and for those accused of consent violations.
The activism aspect of "Consent Counts" will be equally multifaceted. We have already begun reaching out to law enforcement, to legislators and to educators. In the coming year, we will be presenting continuing legal education (CLE) programs to lawyers, working with bar associations and law student groups, and participating selectively with "friend of the court" briefs in legal cases. Further down the road is the development of grass roots activism to change state laws and law enforcement practices.
In all of this, we need your help. You can report BDSM-related criminal investigations and prosecutions to NCSF. Your local groups can host "Consent Counts" presentations and discussions on activism strategies and on community practices that can help avoid criminal problems. As we go forward, we are seeking volunteers for various forms of activism and educational outreach. And, of course, your continuing donations to the NCSF Foundation (tax-deductible) and NCSF are essential for making this project effective.
NCSF's 2014 Roundup
NCSF's 2014 Roundup 2014 has been a year of progress for NCSF and for people who are kinky and nonmonogamous. The national conversation about gay marriage, consent, and even Fifty Shades of Grey are transforming mainstream attitudes. The change in the American Psychiatric Association's DSM-5 stating that BDSM is a healthy form of sexual expression has also had a significant impact on both the courts and public opinion about kink. Education Outreach Project The NCSF Board Members and presenters gave Education Outreach Project workshops and tabled at 36 events in 2014 (compared to 22 in 2013), with a…
National Coalition for Sexual Freedom: Are you ready for the Fifty Shades of Gray Movie?
Does your media agency have resources for these special interest pieces? Contact the National Coalition for Sexual Freedom for interviews and information on kink and open relationships. NCSF is the national advocate for consensual adult sexual expression. Why kink? There has been a significant interest in BDSM sparked by the wildly successful Fifty Shades of Grey. Similar topics appeared in recent TV Shows from CSI to House to Desperate Housewives, and even animated shows such as American Dad. Furthermore many people, married and otherwise, are discovering and practicing non-monogamy. From polyamory to swinging to open relationships, a notable percentage of the public are shifting their relationship parameters in an honest…
Media Kit
50 Shades of NCSF Palm Cards
GayLawNet Joins Forces with NCSF
NCSF's Kink Aware Professionals joins forces with GayLawNet NCSF has expanded the reach of its Kink Aware Professionals by collaborating with GayLawNet, which now offers a way for lawyers in their database to self-identify as Kink Aware Professionals: gaylawnet.com/attorneys/ussolc.html "Whenever someone can't find a lawyer in NCSF's KAP list, I always refer them to GayLawNet," says Susan Wright, spokesperson for NCSF. "Many of their gay-friendly lawyers are eager to work with kinky people, and the GayLawNet database is huge." NCSF recently started an outreach campaign to the lawyers who have listed themselves on GayLawNet to let them…
Tides Awards NCSF $1,500 Grant
NCSF Receives Grant Award NCSF is proud to announce the receipt of a $1,500 grant awarded by Tides Foundation. About Tides #TidesProject "Since 1976, Tides Foundation has worked with over 15,000 individuals and organizations in the mutual endeavor to make the world a better place. These include foundations, donors, corporations, social investors, nonprofit organizations, government institutions, community organizations, activists, social entrepreneurs, and more. We break down the walls between entrepreneurs and their efforts to bring positive change to their communities. We are all about new ideas, innovation, and providing the tools to make these great ideas a reality." NCSF is…
NCSF Mental Health Survey
NCSF Mental Health Survey Please take the NCSF Mental Health Survey! We would like to know more about your BDSM practices, mental health and relational violence experiences: https://www.surveymonkey.com/s/FZ2XDMP NCSF is working with researchers at Sam Houston University's Department of Psychology and Philosophy who will compare our responses to two other sample populations – one college-aged and the other LGBT. NCSF will use these results to help with our advocacy, benefiting both existing and developing programs. Specifically, the study's results will assist in educating law enforcement, legal and psychological professionals about the practices and mental health of BDSM practitioners. The survey…
Military Court Accepts NCSF's Amicus Brief
Military Court Accepts NCSF's Amicus Brief in Support of Consensual Nonmonogamy April 24, 2014 – Washington, DC – The Navy and Marine Corps Court of Criminal Appeals has accepted NCSF's amicus ("friend of the court") brief advising the court that prosecutors are avoiding the Supreme Court decision, made in Lawrence v. Texas, that moral judgment is not a basis for criminalizing consensual sexual conduct, and that consensual sex should only be criminalized if that conduct is injurious or goes against a valid societal interest. In the appellate case, it was argued that the activities were "public" even though the sexual…
Ombudsman Committee Established
NCSF Appoints Members of the Ombuds Committee June 3, 2014 - NCSF is proud to announce these appointments to the Ombuds Committee: Desmond Ravenstone, James Huesmann and Bjorn Paulee. The Ombuds Committee handles complaints and concerns regarding the conduct of NCSF officers and staff, and the operations of NCSF institutions. The NCSF Ombuds Committee shall be established as an Advisory Committee, as per NCSF bylaws, to review Coalition administration and activities, assuring ethical and effective fulfillment of NCSF's mission and goals. Board Member Fil Vocasek is the Board Liaison to the Ombuds Committee. NCSF thanks the three members…
NCSF Files Amicus Brief in Military Court
NCSF Files Amicus Brief in Support of Consensual Nonmonogamy March 26, 2014 – Washington D.C. – NCSF has filed an amicus brief in a military case involving a marine who engaged in a consensual threesome and because of that was convicted of adultery, attempted consensual sodomy and indecent conduct, a "crime" based solely on undefined sexual conduct inconsistent with "common propriety." In its brief, NCSF points out that military law is out of sync with U.S. Constitutional law and societal mores, especially when it comes to consensual sexual behaviors. Dick Cunningham, NCSF's Legal Counsel who prepared and filed…
- Dealing with Assault - understand your rights and options when it comes to consent violations.
- Is this Assault - Guide for determining wheither a consent violation can legaly be considered assault
- Drawing the Line – Some things your group or club can consider when trying to determine if a member should be disciplined or banned
- Dealing with Consent Incidents – Guide for groups in dealing with consent incidents
- Liability Issues for Groups or Events - Some of the ways a criminal or civil court case can impact your group when a consent violation happens at your play party or event
- Sample Consent Policy - Sample Consent Policy for groups involved in BDSM-Leather-Fetish, swinging, and polyamory lifestyles
- Trauma Pamphlet - Trauma is an injury caused by an outside, usually violent event or experience.
- Power Exchange Statement
- Consent Statement Summary
- Consent Counts Statement
- Consent and its Discontents: AASECT 2016
- Consent Legal Cases
- State by State Assault Laws

subset: commoncrawl


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Celebrity Duets: An Inside Look
Aug 29, 2006 4:00 AM EDT
You've seen them dance. You've seen them lose weight. You've even seen them ice-skate. Now it's time for celebrities to grab a mike and start singing. The contestants on Fox's Celebrity Duets will have a little help from well-known recording artists… Read more


text: It's May on the International Dateline. Welcome to Photo of the Day. The POTD thread was started by iGary in May, 2006 and converted to a monthly thread in November 2007 by Arn. POTD is one of the most popular picture groups on MacRumors, often exceeding 500 posts and 20,000 views per month. Photo of the Day is intended to be a showcase for your best pictures. There is no limit to your gear, just your imagination. P&S and film cameras are welcome along with DSLRs. There are no themes like the Weekly Contest, and no winners (or losers) either. Policies *One Photo per Day - Don't post more than one photo each day. *Multi-Quote - To comment on several photos, click the "+ (Multi-Quote) button. This puts all your comments in one post. Multi-Quoting is required on all of the MacRumors forums. *SFW (Safe for Work) only - This is a site - wide rule. If you wouldn't show it in a public place, then it's NSFW (not safe for work). Think before you post. *Describe your photo - Tell what it is and where you took it. If you know the EXIF data of a photo, include it. The following EXIF fields are recommended: Camera, ISO, Focal Length, Shutter/Aperture and Lens. Note: Anyone may start the Photo of the Day thread on the first of the month GMT. Please copy a quote of this post to maintain all the formatting. ** To see all of our past POTD threads please see the sticky thread here** Here's one for all you dads out there ... Mister Loo Rolls by Hugh Russell, on Flickr Cheers Hugh


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Fordham University law student Jenny Edelman (pictured) cheered yesterday when she heard that the Supreme Court had upheld ObamaCare.
A provision allowed Edelman, then 25, last year to obtain coverage as a dependent under her dad's family-insurance plan.
"I am in school, not working," said Edelman, whose "runner's knee" required surgery. "I would not have affordable health insurance if the law was overturned."
Her patella femoral syndrome "is very painful," she said. "I've been in and out of therapy since I was 12."
At times she's needed physical therapy twice a week. Had the Affordable Care Act been struck down, she might have had to seek pricier, less comprehensive coverage.
"For me to get a policy on my own would easily be $1,000 a month," said the Manhattan resident. "I wouldn't be able to afford my own insurance plan.
"Now I get a physical every year, I go to the eye doctor, I go to the dentist when I need to."
And insurers can't deny her coverage for a pre-existing condition.


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I couldn´t really warm up to the other loopers around. The Boss RC series is mono, the Digitech Jamman is more a phrase sampler, and the Looperlative...? Well, did it actually make it beyond prototype status?
I have been using a Looperlative LP-1 for 3 years now. Its expensive, but its stereo and its actually 8 loopers in one box. It has deep program-ability and customer service is amazing. No way I would ever go back.Just my 2 cents.
Thanks guys for the input. As for the timefactor sounding bad, that's the first I've heard of this. The common complaint I've heard is the delays are on the short side, but nothing of the sound quality. As for using a laptop and Live, I can understand the attraction but I will be using logic on my laptop, and buying another laptop just to run Ableton, plus the cost of the software, and that APC40 thing would be the most expensive option of them all, even with near endless looping. And that APC40 from what I saw in the demo it looks like its mostly designed for playing back pre-recorded loops. I'm more interested in doing some live looping on the fly, not going to playback much pre-recorded loops. And probably the biggest reason I won't be going the Live route is I don't want to, or even have time to learn another piece of complicated software. This gig is coming up in a little over two months. Scott, thanks for the heads up on that Behringer pedalboard, I'll be checking that out if I end up going the Looperlative or EDP route.
Another element to think about when buying a looper is if it is important to you to allow loops to fade out while you're adding new parts or not. Some sort of feedback control is required if that is the case. (Most loopers will just loop endlessly - though with some, the loop level will decrease slightly when you record on top, to help prevent distortion.)
A friend of mine bought a Digitech Jamman, a regular looper. He had problems every time he would record more than 3 or 4 layers, they would get out of sync. He had it replaced by a new one, same thing.
QuoteA friend of mine bought a Digitech Jamman, a regular looper. He had problems every time he would record more than 3 or 4 layers, they would get out of sync. He had it replaced by a new one, same thing. I had the same problem; that thing sucked. I traded it up for a Yamaha SU200.


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Mickey Hatcher Vindicated
The "Fire Scioscia!" "Fire Hatcher!" crowd has all but disappeared from the fan boards in recent days, as the Angels have the best record in the American League at 63-40 (.612) despite losing Vlad Guerrero and Torii Hunter in July, not to mention all the other injuries and disasters that befell the team this year.
Despite the blather from the statheads who've condemned the Angels for not marching in goosestep to sabermetric fundamentalism, the Angels lead the A.L. in runs (590), hits (1,040), RBI (563), and batting average (.290). They're second in on-base percentage (.353) but only seventh in walks (348), about 100 fewer than the Yankees (446). They're third in slugging percentage (.451), even though they're only tenth in homers (114).
I coined the phrase "Contactball" in November 2004 to describe the Angels' offense philosophy. They emphasize putting the ball in play to move up runners and score them when an opportunity presents itself. The strategy works best when the Angels' strikeout rate is low.
The Angels' 644 strikeouts to date rank 11th in the A.L. Contactball is back.
I wrote a blog back in March called "Contactball 101" which discussed in detail the philosophy behind their approach. That was in the spring, when Mike Scioscia and Mickey Hatcher acknowledged their younger hitters were having "plate discipline" problems. Some people use the phrase "plate patience," but from the Angels' perspective they don't mean walks, they mean looking for a pitch that fits the situation. Walks are a byproduct of plate patience, but walks do not create plate patience, a mistaken assumption by the statheads.
Orange County Register sportswriter Bill Plunkett wrote an article published March 5 summing it up:
Angels hitting coach Mickey Hatcher said the emphasis includes some directives this spring for the younger players based on certain scenarios — take a strike when leading off an inning, see as many pitches as possible in your first at-bat against a pitcher, lay off breaking balls and change-ups to "keyhole" on fastballs in certain areas.
"It's going to take us time but this spring training we're really going to focus on that, especially down there with those (minor-league) guys," Hatcher said. "They don't even know what a pitcher's throwing and they're swinging. We preach it and preach it and we weren't getting anything done with it. Now we're going to make it mandatory."
Over the winter, I built a spreadsheet to look at certain long-term trends in the Angels' offense, starting with the 2002 world championship year. One was to look at the number of pitches (NP) taken by an Angels batter per plate appearance (PA), and compared it to the American League average. The results:
When I compiled this table over the winter, I was astonished to see that the number of pitches per plate appearance by the Angels had stayed remarkably consistent from year to year, and in fact in the period 2002-2008 the fewest number of pitches was in the championship year. But the 2002 team's 851 total runs scored was the highest in that period; contrast with 765 in 2008.
The 2009 team, for the first time in that time frame, is actually seeing more pitches than the league average. And they're currently on a pace to score 928 runs, which would blow away the 2002 number. That pace is unlikely to hold, but it's still reasonable to assume they'll top the 2002 total.
I suspect the reason why the 2002 team was productive despite their lower rate of pitches seen per at-bat was that they had a largely veteran lineup. As Hatcher noted, the younger hitters were struggling with pitch recognition. The 2002 lineup didn't have youngsters like Erick Aybar, Kendry Morales, Howie Kendrick, Mike Napoli and Jeff Mathis in the lineup. Mathis still struggles to hit well, but the rest have come around, with Howie Kendrick batting .388 since his "time out" in Triple-A the latter half of June.
Let's also give credit, of course, to the veteran presence of Bobby Abreu. Angels beat writer Lyle Spencer of MLB.com suggests that Abreu might be an A.L. MVP candidate, which I think is a stretch, but he certainly deserves consideration (along with Torii Hunter) for the team's MVP. And Chone Figgins is having perhaps the best season of his career, with his .400 OBP setting the table for those to follow.
In any case, it's time for the "Fire Hatcher!" crowd to step forward, admit they were wrong, and give him credit for helping the kids adapt to the big leagues. Just like he said he would in March.


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HTML5 for Digital Advertising Resources
- 1 HTML5 for Digital Advertising Resources Page
- 1.1 HTML5 Tools
- 1.1.1 For Designers
- 1.1.2 For Developers
- 1.2 Video
- 1.3 Animation
- 1.1 HTML5 Tools
HTML5 for Digital Advertising Resources Page
This resources page is intended to supplement the HTML5 for Digital Advertising document and other future developments from the IAB HTML5 Working Group. This page has been seeded with suggestions from the HTML5 Working Group, with participation from web and mobile ad creation practitioners. It is the Working Group's goal to establish a common ground for HTML5 ad creation and optimization while also offering general guidance to designers and developers transferring skillsets.
This resource page provides a starting set of information and tools for developers and designers of HTML5 ads, across three core sections: HTML5 Tools, Video, and Animation. The contents of this page will be updated as the industry adoption of HTML5 evolves and the HTML5 Working Group creates and shares new guidance.
This wiki page is open to any contributor wanting to suggest or update content relevant to the available sections, and it should be considered an open space for industry knowledge share. The IAB does not intend to promote any product or services over another within this resource, and we recommend each company research and evaluate which products and services work best for their own organization.
HTML5 Tools
The HTML5 Tools section is an industry attempt to bring clarity on the different types of tools available to both designers and developers in HTML5 ad creation. Designers will need tools that focus on producing the creative assets, developer's tools for the CSS, JavaScript and HTML5 files. This wiki page is open to any contributor wanting to suggest applicable HTML5 tools for designers or developers. To suggest a tool for this Wiki, please include the following criteria:
- Tool Name
- Tool Audience (Designer/Developer)
- Tool Category (as listed in doc, depends on audience)
- Tool Purpose & Best Practice
For Designers
Image Creation Tools
Adobe Photoshop
Photoshop is used for layered image creation. Creatives should be saved as PNG, JPG or GIF and other tools may be required for sprite creation or size optimizations. Note that Animated GIF images are not supported on many mobile devices.
- Note: Android supports bitmap files in a three formats: .png (preferred), .jpg (acceptable), .gif(discouraged)
- Source: http://developer.android.com/guide/topics/resources/drawable-resource.html
HTML5 Animation Tools
Adobe Edge
HTML5 animation tool has familiar Adobe UI. Relies heavily on external JavaScript libraries that generate output which can be too heavy for mobile.
Sencha Animator
Standards-based HTML5/CSS3 animation tool with key frame control and strong cross-platform support. Extra attention given to mobile ad creation including MRAID-compliant output.
Tumult Hype
Key frame-based animation tool that generates HTML5 content for desktop and mobile. Compatible only with Mac.
''Google Web Designer''
Cross-platform keyframe-based HTML5/CSS3 animation tool with 3D animation, prebuilt and custom components, and direct integration with DoubleClick, AdMob, and Adwords platforms
Flash converters
Adobe Flash Professional Toolkit for Create JS
Convert SWF files with core animation, classic tweens, and sounds to HTML5 using Flash Professional. Intended to "jump-start" your designs for HTML5.
Google Swiffy"
Convert SWF files (SWF 8 and AS 2.0) to HTML5. Output includes images as Base64 so further optimization is limited.
HTML5 website tools
Abode Edge Tools
Adobe's HTML products includes tools building animations, responsive layouts, hand-coding, mobile device previews, web fonts, and hybrid app building. Intended for designer-developers building HTML5 websites, limited in ad creation best practices.
"Google Web Designer"
Cross-platform tool for designing HTML5 and CSS3, including visual and code based tools for keyframe-based animation and 3D transforms
HTML5 mobile rich media
Aarki Encore
Cloud-based creative optimization and media buying platform for video and content-based HTML5 mobile rich media ads. Aarki Encore allows brand marketers, agencies, app developers and publishers to quickly create, flight and optimize high performing mobile ads. Aarki Encore comes with drag-and-drop widgets, top-of-the-line animation, retail inventory feed integration, dynamic distance, high performing ad templates, automatic encoding, dynamic optimization and more.
Celtra AdCreator
Web-based platform for creating, trafficking, and tracking HTML5 mobile rich media ads. AdCreator is an OS and device-agnostic tool with drag-and-drop interface, pre-built components, custom JS to develop on top that lets users create an ad once and run it across many media owners. Offers dynamic ads and a wide array of platform-based, pre-tested formats and features, including location based and social media features.
Crisp Engage
Web application to build, manage, and measure multi-platform rich media ad campaigns. Generates HTML5 ads from templates or from scratch with an emphasis on mobile. Includes MRAID support, ad validator and tester, importers for animation tools, video encoding, and image editing. Creative wizards leverage a library of ad features including web fonts, retina support, geo-location and social APIs. Provides pre-tested universal ad tags for desktop and mobile ad servers
InMobi Studio
Platform to build, run, and measure mobile rich-media ads. Drag-and-drop interface with library of components for common ad-based features like video, geo-location, and gestures. Generates output for smart phone and tablet devices that is MRAID compliant
PointRoll's Composer Ad Builder""
Currently in development, build and output interactive, multi-device digital display ads in both Flash & HTML5 via a single tag — without using Flash authoring software & without writing a single line of code. For both designers & developers who want to dramatically cut production time
"Sizmek Ad Builder for HTML5"
A rapid, codeless HTML5 interactive and animation tool for authoring standard and rich media experiences across desktop and mobile. With point and click components and responsive capabilities, HTML5 ads can either be built from scratch or created from included or user-defined templates. Integrated directly into the Sizmek MDX platform, Ad Builder for HTML5 also benefits from over a decade of robust ad serving features, including dynamic creative, sequenced messaging, and granular creative analytics
"Google Web Designer"
Cross-platform tool for creating rich media and dynamic ads, using keyframe-based HTML5/CSS3 animation, 3D tools, prebuilt and custom components, and direct integration with DoubleClick, AdMob, and Adwords platforms
"Neuranet Fexitive:
Platform for building fully responsive creative in HTML5
For Developers
Browser Reference
Can I Use
Extensive reference on browser support for HTML5 and CSS3 features
HTML5 Please
Reference on browser support for HTML5
CSS3 Please
Reference on browser support for CSS3
HTML Test
Reference to test your web content against current HTML5 compliance
Mobile HTML5
Reference on mobile support for HTML5
JavaScript Libraries
GreenSock JavaScript animation library
Commonly used for JavaScript-based animations, familiar to ActionScript developers in Flash.
"Tumult Hype"
Javascript library for creating interactive HTML5 content and web animations
Zepto is an open source jquery compatible library. If you know jquery, it is easy to use zepto. Zepto offers a very lightweight (~5-10k) library download and fast execution. It may be limited in functionality
Code compression
YUI Compressor
Command-line tool to compress and obfuscate JavaScript and CSS. Can be incorporated with build tools or online versions are available.
Command-line tool to compress JavaScript. Can be incorporated into build tools or online versions are available.
Image compression
Yahoo! Smush.it
Online lossless optimization tool that analyzes a web page and provides compressed images.
Online lossless optimization tool that creates compressed images from uploaded images.
Sprite Generators
Online and bookmarklet tool to create a sprite image and corresponding CSS from an HTML page.
CSS Sprite Generator
Online tool to create a sprite image from a .zip package of images.
Web application with drag-and-drop features to create a sprite.
Command-line tool to create sprite images from a folder.
Web fonts technology
Foundry and tool provider for web fonts. Provides Photoshop plug-ins and HTML building and font-download-optimization tools to incorporate web fonts into creatives.
Adobe Typekit
Commonly known foundry of web fonts, but limited tool support.
"Google Fonts"
Our goal is to create a directory of web fonts for the world to use. Our API service makes it easy to add Google Fonts to a website in seconds. The service runs on Google's servers which are fast, reliable and tested. Google provides this service free of charge.
The HTML5 Video section is a resource for finding the updated browser support and streaming delivery technologies available for browsers and devices. Although the working group will periodically update content within these topics, this section is open to any contributor seeking to provide any new or known updates not yet posted.
Browser Support
While the HTML5 video element is widely supported among the latest major browser vendors, the video asset itself needs to be transcoded into a few different formats to ensure cross browser functionality. The following section allows you to check the most updated browser support:
The following website allows you to check the most updated browser support:
- Desktop:
- Desktop:
MPEG-4/H.264 is most widely supported format for all browsers except IE8
- Mobile:
- Mobile:
MPEG-4/H.264 is most widely compatible format for all mobile phone browsers except for Opera Mini and partial support for Android browser 4.3 and below
Other formats to consider are:
WebM/ Vp8 or VP9
Streaming delivery technologies
There may not be a standard just yet but there are a few technologies we encourage to use when target ads to specific browsers and devices. The following video delivery technologies intended to reduce the video file weight through transport, but not all are supported by all browsers and devices. Delivery specifications are set to evolve in the coming years with the promise of an industry standard. Since most video delivery through the HTML5 video element is a progressive download from server to client, it's encouraged to keep this information in mind when serving video with higher file size to users on devices tied to a cell carrier, as they're often restricted to a limited bandwidth data plan.
HTTP Live Streaming (HLS)
Delivery specification by Apple used to segment a video file into smaller transport streams and deliver it to an end user by way of an .M3U8 file. The M3U8 file is a description file instructing the HTML5 video player on how to playback the video segments. Supported in iOS, Safari and Android 3.0+
MPEG-DASH (Dynamic Adaptive Streaming over HTTP)
Delivery specification similarly as HLS but its instruction file is an .MPD (media presentation description file). Although not supported in any major browser, it does show promise as a ubiquitous streaming solution in the near future as public support ranges from Microsoft, Adobe and Akamai. While not supported in any major browser just yet. More information is available here: http://dashif.org/software/
HTML5 Adaptive Bitrate Streaming
Emerging video delivery technology that sends segments of a video to a user without incurring the extra overhead of progressively loaded content, it also detects bandwidth constraints of the user and adjusts video playback quality accordingly. Support exists with Apple's HTTP Live Streaming (HLS) specification, and in Safari and iOS
Feature Detection for Canvas
Feature detection is used to detect whether features built into an HTML ad are supported in the browser, and if not supported, offer an alternate experience that is executable based on supported features. This section provides guidance in the feature support for Canvas in select browsers. Please note that it is not the exact code to run this function, but the practice to perform the feature detection check that is the recommendation within this resource section.
If Canvas is not supported by the user's browser, the feature detection should provide a fallback user experience. This feature, as well as all new web technology features and functionality can be checked for compatibility on this site: http://caniuse.com/#feat=canvas
- Explorercanvas
<!--[if lt IE 9]> <script src="excanvas.js"></script> <![endif]-->
- The JavaScript file can be downloaded here: http://code.google.com/p/explorercanvas/
- Note Please be aware that this script does not support all Canvas features that may be utilized within any given ad unit and performance can be slow and should be used cautiously


text:
REAL PROPERTY: Sales Ratios of Real Property by Class of Property and County, Calendar Year 2016
Under state law and Ohio Department of Taxation rules, real property in all counties is reappraised at 100 percent of market value every six years and updated the third year after each reappraisal. Thirty-five percent of the market value represents the assessed or taxable valuation of real property.
In order to verify that real property is being assessed at or close to 35 percent of market value, the Department of Taxation surveys real property transferred in each of Ohio's 88 counties. Sales ratios are calculated by dividing the total assessed (taxable) value of the transferred properties by the total consideration (sales price) paid for those properties.
The resulting ratio shows the average taxable value as a percent of the average sales price for each class of property. The lower the ratio, the greater is the amount by which the sales price of the property exceeds its reappraised or updated value.
The attached tables show a summary of sales ratios and numbers of sales for the four classes of property: agricultural, industrial, commercial and residential. Counties were either reappraised or updated in the years 2014 through 2016, these are referred to as groups at the end of each report. These tables do not include property transfers that would make the ratios unrepresentative of sales activity in the area.
The survey for the first six months of 2016 (I/2016):
The survey for the second half of 2016 (II/2016):


text:
Votre titre Audible gratuit
Slouching Towards Bethlehem
Prix : 17,22 €
Audie Award Nominee, Short Stories/Collections, 2013
Universally acclaimed from the time it was first published in 1968, Slouching Towards Bethlehem has been admired for decades as a stylistic masterpiece. Academy Award-winning actress Diane Keaton (Annie Hall, The Family Stone) performs these classic essays, including the title piece, which will transport the listener back to a unique time and place: the Haight-Ashbury district of San Francisco during the neighborhood's heyday as a countercultural center.
This is Joan Didion's first work of nonfiction, offering an incisive look at the mood of 1960s America and providing an essential portrait of the Californian counterculture. She explores the influences of John Wayne and Howard Hughes, and offers ruminations on the nature of good and evil in a Death Valley motel room. Taking its title from W.B. Yeats' poem "The Second Coming", the essays in Slouching Towards Bethlehem all reflect, in one way or another, that "the center cannot hold."
"Diane Keaton does an outstanding job of conveying an era and a place. Her narration is clear, well timed, and wonderfully consistent with the author's voice. Her ability to convey Didion's musings and gentle skepticism add much. Didion's style remains extraordinary." (AudioFile)
Autres livres audio du même :
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- Victoria Wright
- 21/01/2013
Didion deserves better.
Joan Didion's writing is fabulous, insightful, spare. She deserves much better treatment than she gets from Diane Keaton, whom I love as an actress, but who is NOT a good reader. Her mispronunciations are legion, and it is painfully obvious that she is doing this reading cold. But frankly, I blame Audible's obvious desire to whip through these recordings rather than taking the time to produce something flawless--which both the author and the reader deserve. Would it kill them to go back and dub a few mistakes? Didion deserves better.
Still worth a listen, though, because even though Keaton's not so hot, Didion is that good.
82 sur 90 personne(s) ont trouvé cet avis utile.
- Amazon Customer
- 24/11/2016
Wanted to love it; couldn't listen.
What did you like best about Slouching Towards Bethlehem? What did you like least?
Liked best? Well, Joan Didion's writing, of course! Liked least? What a weird clash of writing style and narrator style. My brain recoiled at the strangely off delivery, with dozens of obvious mistakes and hundreds more subtle "mis-aimed" attempts to add expression and dynamism. I love Diane Keaton's acting legacy, and her personal charisma, which shines through her film performances. But as a reader, at least of this kind of material, I could not listen past the first two stories. It's too late to return this book, but it would have been my first return ever at Audible.
Would you be willing to try another one of Diane Keaton's performances?
Almost certainly not. I don't mean to impugn her ability to understand the material, but she read as if Joan Didion's sentence structure was just too much for her. Perhaps Diane began many sentences expecting a certain syntax, and when Joan's sophisticated style took the reader on a delightful little twist, Diane just got lost and delivered the rest of the sentence as best she could. Every couple of paragraphs a nagging feeling resurfaced -- that Diane hadn't seen this material before, much read it less out loud.
Some people just can't read out loud in such a way as to convey the subtler aspects of the author's intent. In other words, some can read the words in a clear, intelligible manner (Diane certainly can), but they don't see what a writer would see, and they don't express what this author is *doing* -- what makes great writing work. Here Diane's delivery was just too inappropriate, unbalanced, oddly off in emphasis and timing. Though a delicate kind of failure, it made Joan's work almost impossible to enjoy, and I couldn't stop thinking of what had been missed in the reading. In fairness to Joan Didion, I stopped listening after an hour or so, and bought the book. Needless to say, the book is memorably successful.
Was Slouching Towards Bethlehem worth the listening time?
Sad to say: definitely not.
Any additional comments?
It pains me to pan this performance so completely, but it also pains me that I spent $15 on this product, so I felt a responsibility to future purchasers. I am also disappointed that Audible's producers didn't pick up on the profound disconnect between reader and writer. I would expect Audible to work with readers, especially famous ones whose names help sell a recording, to ensure a much higher quality reading.
24 sur 26 personne(s) ont trouvé cet avis utile.
- The Companion
- 28/09/2015
Diane Keaton doesn't read this book very well
what can I say. I was as surprised as anyone. There's an underlying childish drawl and she mispronounces words (turns out Joan Didion uses "desultory" quite a bit).
20 sur 22 personne(s) ont trouvé cet avis utile.
- Lemondropkid
- 03/06/2016
Dammit Diane!
Diane Keaton's intonation is exhausting at best. Her pauses are poorly placed and she doesn't seem to respect sentence structure. The book and Joan Didion are perfect and timeless.
18 sur 20 personne(s) ont trouvé cet avis utile.
- AmazonCustomer
- 26/04/2013
Who'd have guessed Diane Keaton can't read?
Wonderfully wrought essays took me back to the 60's, thanks to Didion's sharp eyed portraits and ear for dialogue. However, what is Diane Keaton's excuse?? She mispronounces so many words so consistently it's as if she has a speech impediment (maybe she does). She omits any interior syllable with an "er" sound: "San Berdino;" "vetinarian." This happened so often it was distracting. I actually had to check to see if all these years I had misread San Bernardino CA and it really didn't have that interior "nar" syllable. I have recently read Didion's essays about the deaths of her husband and daughter, and reading her first collection after her latest was an interesting juxtaposition. For all the dystopia she noticed and chronicled in the 60's, she has nevertheless been able to live a good, productive and creative life. She is a treasure.
37 sur 42 personne(s) ont trouvé cet avis utile.
- wsp
- 25/01/2016
Narrator ruins it beyond repair
I wish I had read the other reviews before purchasing. Who would guess that Diane Keaton would be such a horrible narrator? Between her wooden amateurish performance and her mispronunciation I had to quit listening, even though the stories are well written.
26 sur 30 personne(s) ont trouvé cet avis utile.
- Debbie Duncan
- 30/01/2013
Diane Keaton takes California out of Joan Didion
Would you recommend this book to a friend? Why or why not?
Book: absolutely. Audiobook: not at ALL.
What was the most compelling aspect of this narrative?
Didion's amazing ability to describe time, place, characters.
How could the performance have been better?
Let me count the ways! San Bernardino (first story's setting, mentioned in the second sentence and about a dozen times after that) has never been called "San Bern-dino." Merced is not "MURSE-ed." Sausalito is not "Souse-alito." These are real towns, important to the script (if you will). Correct pronunciation should not be optional!
Diane Keaton isn't the first I've heard pronounce Washington "Warshington," but ... really? In a professional production? Was no one directing? Editing? Audible should be embarrassed.
Any additional comments?
This recording needs to be corrected if Audible continues to sell it. I have bought and listened to dozens of audiobooks; none has been this bad. As another reviewer noted, Didion deserved better. So do Audible's customers. I had to stop listening and go buy the paperback book before Diane Keaton completely ruined it for me.
53 sur 62 personne(s) ont trouvé cet avis utile.
- Michael
- 03/12/2013
Buy the book. Avoid the audio.
What disappointed you about Slouching Towards Bethlehem?
I had to stop listening after about 5 minutes. I've never been to California - I've lived in Missouri my whole life. But I know that "San Bernardino" is not pronounced: "San Berdino." I suppose it's possible Keaton knows something I don't about the way the locals pronounce things in casual conversation. But at *best* this performance would be something like replacing "you" with "ya'll." It's grating. Language matters to Didion:"I am still committed to the idea that the ability to think for one's self depends upon one's mastery of the language, and I am not optimistic about children who will settle for saying, to indicate that their mother and father do not live together, that they come from 'a broken home.'"Her language is, in my view, butchered here. Shame on Audible for publishing the audiobook in this state. Buy the book - the prose is excellent. I'm getting my money back for the audio version.
26 sur 31 personne(s) ont trouvé cet avis utile.
- Jack
- 15/11/2013
Great Essays - Bad Narration
I am a fan of Joan Didion & am very pleased that so much of her work is available on Audible.
Diane Keaton does such a bad job. Her voice is slurry and laconic, through a lot of passages she sounds bored. The entire Hawaii essay is read as if by a person being forced to do it. She gets lost in sentences, she reads with no real interest. It's droney and to be honest I found my mind wandering through much of her reading.
If you would like to hear Joan Didion read by an accomplished narrator, check out the White Album, the reader there gives one of the best performances I've ever heard on Audible.
15 sur 20 personne(s) ont trouvé cet avis utile.
- 20/09/2012
Keaton is disappointing
Any additional comments?
Hearing Diane Keaton pronounce tule fog as "tool" fog and Merced as "mers-ed" (emphasis on the first syllable rather than on the last) was a little jarring. Aren't there editors involved to help the readers pronounce the words correctly? Keaton is a good reader for Didion's slightly smug tone here, but those errors were disappointing.
20 sur 27 personne(s) ont trouvé cet avis utile.


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Silver Spring, Md — Motionsoft has received encouraging responses to its acquisition of Conexion, according to Motionsoft CEO Al Noshirvani. The Silver Spring, MD-based club management solutions provider announced the acquisition of both Baltimore-based Conexion and Conexion Tan last month. Terms of the deal were not disclosed.
"The feedback we have received from customers, prospects and the industry at-large has been tremendous," Noshirvani says. "The most exciting piece of news is with regard to our sales volume."
The acquisition expands the company's client base to more than 1,500 health and fitness clubs, hospital and corporate wellness centers, university-based facilities and tanning salons worldwide. It also more than doubles Motionsoft's annual operating revenues, according to a company press release.
Noshirvani says that Motionsoft's variety of services prompted more than 160 locations to choose Motionsoft between June 1 and late July.
"The combination of Motionsoft and Conexion provides us greater access to industry know-how and capital funds which, in turn, solidifies our promise to deliver premium club management solutions — from software, financial services, and beyond," Noshirvani says. "Clients will continue to find Motionsoft as an organization that develops tailored solutions able to meet specific client requirements allowing for greater flexibility and control of their businesses."
Noshirvani will remain as Motionsoft CEO. Conexion CEO Benson Fine was appointed Motionsoft's chairman of the board. The rest of the management team of the combined organization, which will market under the Motionsoft brand, includes senior managers and executives from both companies.
Conexion had specialized in club management software, accounts receivables and financial services programs.
"Like Conexion, Motionsoft has served the health and wellness industry for over 25 years," Fine says. "Our companies are synergistic. Our management teams, products and services offerings, and commitment to excellent service make this pairing particularly advantageous to our clients and the entire industry."


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NEW YORK – Major League Soccer announced today the launch of the 2012 MLS W.O.R.K.S. Community MVP contest. During the 4-week contest, fans throughout the League will have an opportunity to nominate themselves or other individuals who are committed to going above and beyond to make a difference in their communities. Winners will be selected based on their efforts in one of the following areas: general community service; youth programming; environmental sustainability; health and wellness; education; military or civic service.
One (1) Community MVP will be chosen to represent each of the 19 MLS clubs and will receive a prize package including VIP tickets, local recognition and an autographed item. One (1) Grand Prize winner will receive a $10,000 donation to the charity of their choice and a trip to the 2012 AT&T MLS All-Star Game at PPL Park on July 25. Chelsea FC, winner of this year's UEFA Champions League, will return as the AT&T MLS All-Star Game opponent. The Grand Prize winner will receive roundtrip airfare, two nights' accommodation, a crystal award from Tiffany & Co. and official MLS merchandise as part of the prize package.
The MLS W.O.R.K.S. Community MVP contest will be open until June 21, 2012 at 7:59 p.m. ET. Nominations must be 500 words or less and can be submitted by visiting the Community MVP website. Following the announcement of the local winners, fans will have an opportunity to vote for one (1) Grand Prize winner by visiting the Community MVP website or the MLS W.O.R.K.S. tab on Facebook from July 2 – July 13. The Grand Prize winner will be announced during halftime of the 2012 AT&T MLS All-Star Game at PPL Park.
A component of Unite. Volunteer. Serve., the Community MVP contest seeks to identify MLS fans who are passionate about making a difference in the lives they touch and are dedicated to improving their communities. Unite. Volunteer. Serve., the League's community service program, is a collaborative effort to combine sport and service, promote goodwill within MLS markets and improve lives and communities at the grassroots level.


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Data mining is commonly used to find otherwise undetectable patterns in related sets of data. However, sometimes these patterns provide absolutely useless information. This story on FoxNews.com explains a recent correlation between teens who skip breakfast and those that lose their virginity earlier in life. Interesting information, yes, but what exactly does a parent or other concerned party do with this? Is it really valuable?
In the business world, I'm sure we could find examples of data mining "hits" that are just as obscure. Many of them have value, but the real intelligence – I mean human knowledge, not some component of software – is being able to determine which patterns are actually useful. Delivering bits of information such as the example above could lead to information overload and defeat the business purpose of data mining.
Now I'm off to evaluate whether I should force Cocoa Crispies into my kids to keep them abstinent 🙂


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Summary: DNA polymerase III beta subunit, N-terminal domain
Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.
This is the Wikipedia entry entitled "DNA clamp". More...
The Wikipedia text that you see displayed here is a download from Wikipedia. This means that the information we display is a copy of the information from the Wikipedia database. The button next to the article title ("Edit Wikipedia article") takes you to the edit page for the article directly within Wikipedia. You should be aware you are not editing our local copy of this information. Any changes that you make to the Wikipedia article will not be displayed here until we next download the article from Wikipedia. We currently download new content on a nightly basis.
Does Pfam agree with the content of the Wikipedia entry ?
Pfam has chosen to link families to Wikipedia articles. In some case we have created or edited these articles but in many other cases we have not made any direct contribution to the content of the article. The Wikipedia community does monitor edits to try to ensure that (a) the quality of article annotation increases, and (b) vandalism is very quickly dealt with. However, we would like to emphasise that Pfam does not curate the Wikipedia entries and we cannot guarantee the accuracy of the information on the Wikipedia page.
Editing Wikipedia articles
Before you edit for the first time
Wikipedia is a free, online encyclopedia. Although anyone can edit or contribute to an article, Wikipedia has some strong editing guidelines and policies, which promote the Wikipedia standard of style and etiquette. Your edits and contributions are more likely to be accepted (and remain) if they are in accordance with this policy.
You should take a few minutes to view the following pages:
How your contribution will be recorded
Anyone can edit a Wikipedia entry. You can do this either as a new user or you can register with Wikipedia and log on. When you click on the "Edit Wikipedia article" button, your browser will direct you to the edit page for this entry in Wikipedia. If you are a registered user and currently logged in, your changes will be recorded under your Wikipedia user name. However, if you are not a registered user or are not logged on, your changes will be logged under your computer's IP address. This has two main implications. Firstly, as a registered Wikipedia user your edits are more likely seen as valuable contribution (although all edits are open to community scrutiny regardless). Secondly, if you edit under an IP address you may be sharing this IP address with other users. If your IP address has previously been blocked (due to being flagged as a source of 'vandalism') your edits will also be blocked. You can find more information on this and creating a user account at Wikipedia.
If you have problems editing a particular page, contact us at email@example.com and we will try to help.
Contact us
The community annotation is a new facility of the Pfam web site. If you have problems editing or experience problems with these pages please contact us.
DNA clamp Edit Wikipedia article
A DNA clamp, also known as a sliding clamp, is a protein fold that serves as a processivity-promoting factor in DNA replication. As a critical component of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand. The clamp-polymerase protein–protein interactions are stronger and more specific than the direct interactions between the polymerase and the template DNA strand; because one of the rate-limiting steps in the DNA synthesis reaction is the association of the polymerase with the DNA template, the presence of the sliding clamp dramatically increases the number of nucleotides that the polymerase can add to the growing strand per association event. The presence of the DNA clamp can increase the rate of DNA synthesis up to 1,000-fold compared with a nonprocessive polymerase.[2]
The DNA clamp fold is an α+β protein that assembles into a multimeric structure that completely encircles the DNA double helix as the polymerase adds nucleotides to the growing strand.[3] The DNA clamp assembles on the DNA at the replication fork and "slides" along the DNA with the advancing polymerase, aided by a layer of water molecules in the central pore of the clamp between the DNA and the protein surface. Because of the toroidal shape of the assembled multimer, the clamp cannot dissociate from the template strand without also dissociating into monomers.
The DNA clamp fold is found in bacteria, archaea, eukaryotes and some viruses. In bacteria, the sliding clamp is a homodimer composed of two identical beta subunits of DNA polymerase III and hence is referred to as the beta clamp. In archaea[4] and eukaryotes, it is a trimer composed of three molecules of PCNA. The T4 bacteriophage also uses a sliding clamp, called gp45 that is a trimer similar in structure to PCNA but lacks sequence homology to either PCNA or the bacterial beta clamp.[3]
|Sliding clamp protein
|Multimer state
|Associated polymerase
|beta subunit of pol III
|DNA polymerase III
|archaeal PCNA
|pol ε
|DNA polymerase delta
|gp43 / gp45
|RB69 Pol / T4 Pol
|DNA polymerase III subunit beta
Crystallographic structure of the dimeric DNA polymerase beta subunit from E. coli.[5]
|Escherichia coli
|RefSeq (Prot)
|Other data
|EC number
|MG1655: 3.88 - 3.88 Mb
The beta clamp is a specific DNA clamp and a subunit of the DNA polymerase III holoenzyme found in bacteria. Two beta subunits are assembled around the DNA by the gamma subunit and ATP hydrolysis; this assembly is called the pre-initiation complex. After assembly around the DNA, the beta subunits' affinity for the gamma subunit is replaced by an affinity for the alpha and epsilon subunits, which together create the complete holoenzyme.[6][7][8] DNA polymerase III is the primary enzyme complex involved in prokaryotic DNA replication.
The gamma complex of DNA polymerase III, composed of γδδ'χψ subunits, catalyzes ATP to chaperone two beta subunits to bind to DNA. Once bound to DNA, the beta subunits can freely slide along double stranded DNA. The beta subunits in turn bind the αε polymerase complex. The α subunit possesses DNA polymerase activity and the ε subunit is a 3'-5' exonuclease.[8]
The beta chain of bacterial DNA polymerase III is composed of three topologically equivalent domains (N-terminal, central, and C-terminal). Two beta chain molecules are tightly associated to form a closed ring encircling duplex DNA.
As a drug target
Certain NSAIDs (carprofen, bromfenac, and vedaprofen) exhibit some suppression of bacterial DNA replication by inhibiting bacterial DNA clamp.[9]
|proliferating cell nuclear antigen
|Other data
|EC number
|Chr. 20 pter-p12
The sliding clamp in eukaryotes is assembled from a specific subunit of DNA polymerase delta called the proliferating cell nuclear antigen (PCNA). The N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA.
The sequence of PCNA is well conserved between plants, animals and fungi, indicating a strong selective pressure for structure conservation, and suggesting that this type of DNA replication mechanism is conserved throughout eukaryotes.[11][12] Homologues of PCNA have also been identified in the archaea (Euryarchaeota and Crenarchaeota) and in Paramecium bursaria Chlorella virus 1 (PBCV-1) and in nuclear polyhedrosis viruses.
|DNA polymerase accessory protein 45
Crystallographic structure of the trimeric gp45 sliding clamp from bacteriophage T4.[13]
|Enterobacteria phage T4
|RefSeq (Prot)
|Other data
|EC number
|1: 0.03 - 0.03 Mb
The viral gp45 sliding clamp subunit protein contains two domains. Each domain consists of two alpha helices and two beta sheets – the fold is duplicated and has internal pseudo two-fold symmetry.[14] Three gp45 molecules are tightly associated to form a closed ring encircling duplex DNA.
Sliding clamps are loaded onto their associated DNA template strands by specialized proteins known as "sliding clamp loaders", which also disassemble the clamps after replication has completed. The binding sites for these initiator proteins overlap with the binding sites for the DNA polymerase, so the clamp cannot simultaneously associate with a clamp loader and with a polymerase. Thus the clamp will not be actively disassembled while the polymerase remains bound. DNA clamps also associate with other factors involved in DNA and genome homeostasis, such as nucleosome assembly factors, Okazaki fragment ligases, and DNA repair proteins. All of these proteins also share a binding site on the DNA clamp that overlaps with the clamp loader site, ensuring that the clamp will not be removed while any enzyme is still working on the DNA. The activity of the clamp loader requires ATP hydrolysis to "close" the clamp around the DNA.
- ^ PDB: 1W60; Kontopidis G, Wu SY, Zheleva DI, Taylor P, McInnes C, Lane DP, Fischer PM, Walkinshaw MD (February 2005). "Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design". Proc. Natl. Acad. Sci. U.S.A. 102 (6): 1871–6. doi:10.1073/pnas.0406540102. PMC 548533 . PMID 15681588.
- ^ V. Mizrahi; R. N. Henrie; J. F. Marlier; K. A. Johnson; S. J. Benkovic (1985). "Rate-limiting steps in the DNA polymerase I reaction pathway". Biochemistry. 24 (15): 4010–4018. doi:10.1021/bi00336a031.
- ^ a b Bruck I, O'Donnell M (2001). "The ring-type polymerase sliding clamp family". Genome Biol. 2 (1): REVIEWS3001. doi:10.1186/gb-2001-2-1-reviews3001. PMC 150441 . PMID 11178284.
- ^ Matsumiya S, Ishino Y, Morikawa K (January 2001). "Crystal structure of an archaeal DNA sliding clamp: Proliferating cell nuclear antigen from Pyrococcus furiosus". Protein Sci. 10 (1): 17–23. doi:10.1110/ps.36401. PMC 2249843 . PMID 11266590.
- ^ PDB: 1MMI; Oakley AJ, Prosselkov P, Wijffels G, Beck JL, Wilce MC, Dixon NE (July 2003). "Flexibility revealed by the 1.85 Å crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III". Acta Crystallogr. D. 59 (Pt 7): 1192–9. doi:10.1107/S0907444903009958. PMID 12832762.
- ^ Lewin, Benjamin (1997). Genes VI. Oxford [Oxfordshire]: Oxford University Press. pp. 484–7. ISBN 0-19-857779-6.
- ^ Lehninger, Albert L (1975). Biochemistry: The Molecular Basis of Cell Structure and Function. New York: Worth Publishers. p. 894. ISBN 0-87901-047-9.
- ^ a b Stukenberg PT, Studwell-Vaughan PS, O'Donnell M (June 1991). "Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme". J. Biol. Chem. 266 (17): 11328–34. PMID 2040637.
- ^ Yin Z, Wang Y, Whittell LR, Jergic S, Liu M, Harry E, Dixon NE, Kelso MJ, Beck JL, Oakley AJ (2014). "DNA Replication Is the Target for the Antibacterial Effects of Nonsteroidal Anti-Inflammatory Drugs". Chemistry & Biology. 21: 481–487. doi:10.1016/j.chembiol.2014.02.009. PMID 24631121.
- ^ PDB: 1AXC; Gulbis JM, Kelman Z, Hurwitz J, O'Donnell M, Kuriyan J (October 1996). "Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA". Cell. 87 (2): 297–306. doi:10.1016/S0092-8674(00)81347-1. PMID 8861913.
- ^ Suzuka I, Hata S, Matsuoka M, Kosugi S, Hashimoto J (January 1991). "Highly conserved structure of proliferating cell nuclear antigen (DNA polymerase delta auxiliary protein) gene in plants". Eur. J. Biochem. 195 (2): 571–5. doi:10.1111/j.1432-1033.1991.tb15739.x. PMID 1671766.
- ^ Marshall, Andrew C.; Kroker, Alice J.; Murray, Lauren A.M.; Gronthos, Kahlia; Rajapaksha, Harinda; Wegener, Kate L.; Bruning, John B. (Feb 2017). "Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21". FEBS J. 284: 985–1002. doi:10.1111/febs.14035. PMID 28165677.
- ^ PDB: 1CZD; Moarefi I, Jeruzalmi D, Turner J, O'Donnell M, Kuriyan J (March 2000). "Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage". J. Mol. Biol. 296 (5): 1215–23. doi:10.1006/jmbi.1999.3511. PMID 10698628.
- ^ Steitz TA, Shamoo Y (1999). "Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex". Cell. 99 (2): 155–166. doi:10.1016/S0092-8674(00)81647-5. PMID 10535734.
Further reading
- Clamping down on pathogenic bacteria – how to shut down a key DNA polymerase complex. Quips at PDBe
- Watson JD, Baker TA, Bell SP, Gann A, Levine M, Losick R (2004). Molecular Biology of the Gene. San Francisco: Pearson/Benjamin Cummings. ISBN 0-8053-4635-X.
External links
- SCOP DNA clamp fold
- CATH box architecture
- clamp protein DnaN, E coli at the US National Library of Medicine Medical Subject Headings (MeSH)
This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.
This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.
DNA polymerase III beta subunit, N-terminal domain Provide feedback
A dimer of the beta subunit of DNA polymerase beta forms a ring which encircles duplex DNA. Each monomer contains three domains of identical topology and DNA clamp fold.
Literature references
Kong XP, Onrust R, O'Donnell M, Kuriyan J; , Cell 1992;69:425-437.: Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. PUBMED:1349852 EPMC:1349852
Internal database links
|DNA_pol3_beta_2 DNA_pol3_beta_3
|Similarity to PfamA using HHSearch:
|DNA_pol3_beta_2 DNA_pol3_beta_3
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR022634
DNA polymerase III is a complex, multichain holoenzyme responsible for most of the replicative synthesis in bacteria [PUBMED:8548826]. It functions by adding nucleotide triphosphate (dNTP) residues to the 5'-end of a growing DNA chain, using a complementary DNA as template. The elongation factor beta-clamp, also called beta subunit, is part of the DNA polymerase III holoenzyme. However, beta-clamp is not attached to polymerase III permanently like the other subunits. It is loaded on the DNA, by clamp loader, a subunit of DNA Pol III [PUBMED:27499105].
The beta clamp forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The bacterial beta clamp is a homodimer; each monomer consists of three globular domains to yield a six-domain ring [PUBMED:18191219]. It is structurally similar to the trimeric ring formed by proliferating cell nuclear antigen (PCNA) (found in eukaryotes and archaea) and the processivity factor (found in bacteriophages T4 and RB69) [PUBMED:1358275]. This structural correspondence further substantiates the mechanistic connection between eukaryotic and prokaryotic DNA replication that has been suggested on biochemical grounds.This entry describes the N-terminal domain of the beta sliding clamp.
Gene Ontology
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component
|DNA polymerase III complex (GO:0009360)
|Molecular function
|3'-5' exonuclease activity (GO:0008408)
|DNA-directed DNA polymerase activity (GO:0003887)
|DNA binding (GO:0003677)
|Biological process
|DNA replication (GO:0006260)
Domain organisation
Below is a listing of the unique domain organisations or architectures in which this domain is found. More...
The graphic that is shown by default represents the longest sequence with a given architecture. Each row contains the following information:
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Pfam Clan
This family is a member of clan DNA_clamp (CL0060), which has the following description:
Sliding DNA clamps are ring-shaped proteins that allow DNA polymerase to achieve high processivity during chromosome replication by tethering the polymerase catalytic subunit to DNA. All of the structures share a 12-fold symmetry around the ring consisting of a simple structural repeat, though there is structural divergence in some of the repeats. Bacterial beta-clamps contain six repeats per subunit with two subunits per ring while the eukaryotic and bacteriophage clamps contain four repeats per subunit with three subunits per ring. Pairs of these repeats form a domain, which has been termed the 'processivity fold'; thus the ring of the sliding clamp contains six domains and therefore is often described as having 6-fold symmetry. A structural representative of a fourth family of processivity fold proteins, namely the herpes simplex virus UL42 protein, is also available. UL42 does not form a ring-shaped clamp, however, but rather functions as a monomer and interacts with DNA quite differently than do sliding clamps; it has been suggested that UL42 resembles a primitive ancestor of sliding clamps [2].
The clan contains the following 13 members:DNA_pol3_beta DNA_pol3_beta_2 DNA_pol3_beta_3 DNA_PPF gp45-slide_C Herpes_DNAp_acc Herpes_PAP Herpes_UL42 Hus1 PCNA_C PCNA_N Rad1 Rad9
We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets, the UniProtKB sequence database, the NCBI sequence database, and our metagenomics sequence database. More...
There are various ways to view or download the sequence alignments that we store. We provide several sequence viewers and a plain-text Stockholm-format file for download.
Alignment types
We make a range of alignments for each Pfam-A family:
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- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- UniProt
- alignment generated by searching the UniProtKB sequence database using the family HMM
- alignment generated by searching the NCBI sequence database using the family HMM
- meta
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
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You can download (or view in your browser) a text representation of a Pfam alignment in various formats:
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View options
We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.
|Representative proteomes
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.
|Representative proteomes
|Raw Stockholm
You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.
HMM logo
HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...
If you find these logos useful in your own work, please consider citing the following article:
This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.
Note: You can also download the data file for the tree.
Curation and family details
This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.
|Seed source:
|Pfam-B_631 (release 2.1)
|Previous IDs:
|Sequence Ontology:
|Bateman A , Griffiths-Jones SR
|Number in seed:
|Number in full:
|Average length of the domain:
|119.80 aa
|Average identity of full alignment:
|28 %
|Average coverage of the sequence by the domain:
|32.24 %
HMM information
|HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
|Model details:
|Model length:
|Family (HMM) version:
|download the raw HMM for this family
Species distribution
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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...
This chart is a modified "sunburst" visualisation of the species tree for this family. It shows each node in the tree as a separate arc, arranged radially with the superkingdoms at the centre and the species arrayed around the outermost ring.
How the sunburst is generated
The tree is built by considering the taxonomic lineage of each sequence that has a match to this family. For each node in the resulting tree, we draw an arc in the sunburst. The radius of the arc, its distance from the root node at the centre of the sunburst, shows the taxonomic level ("superkingdom", "kingdom", etc). The length of the arc represents either the number of sequences represented at a given level, or the number of species that are found beneath the node in the tree. The weighting scheme can be changed using the sunburst controls.
In order to reduce the complexity of the representation, we reduce the number of taxonomic levels that we show. We consider only the following eight major taxonomic levels:
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Colouring and labels
Segments of the tree are coloured approximately according to their superkingdom. For example, archeal branches are coloured with shades of orange, eukaryotes in shades of purple, etc. The colour assignments are shown under the sunburst controls. Where space allows, the name of the taxonomic level will be written on the arc itself.
As you move your mouse across the sunburst, the current node will be highlighted. In the top section of the controls panel we show a summary of the lineage of the currently highlighed node. If you pause over an arc, a tooltip will be shown, giving the name of the taxonomic level in the title and a summary of the number of sequences and species below that node in the tree.
Anomalies in the taxonomy tree
There are some situations that the sunburst tree cannot easily handle and for which we have work-arounds in place.
Missing taxonomic levels
Some species in the taxonomic tree may not have one or more of the main eight levels that we display. For example, Bos taurus is not assigned an order in the NCBI taxonomic tree. In such cases we mark the omitted level with, for example, "No order", in both the tooltip and the lineage summary.
Unmapped species names
The tree is built by looking at each sequence in the full alignment for the family. We take the name of the species given by UniProt and try to map that to the full taxonomic tree from NCBI. In some cases, the name chosen by UniProt does not map to any node in the NCBI tree, perhaps because the chosen name is listed as a synonym or a misspelling in the NCBI taxonomy.
So that these nodes are not simply omitted from the sunburst tree, we group them together in a separate branch (or segment of the sunburst tree). Since we cannot determine the lineage for these unmapped species, we show all levels between the superkingdom and the species as "uncategorised".
Since we reduce the species tree to only the eight main taxonomic levels, sequences that are mapped to the sub-species level in the tree would not normally be shown. Rather than leave out these species, we map them instead to their parent species. So, for example, for sequences belonging to one of the Vibrio cholerae sub-species in the NCBI taxonomy, we show them instead as belonging to the species Vibrio cholerae.
Too many species/sequences
For large species trees, you may see blank regions in the outer layers of the sunburst. These occur when there are large numbers of arcs to be drawn in a small space. If an arc is less than approximately one pixel wide, it will not be drawn and the space will be left blank. You may still be able to get some information about the species in that region by moving your mouse across the area, but since each arc will be very small, it will be difficult to accurately locate a particular species.
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The tree shows the occurrence of this domain across different species. More...
Species trees
We show the species tree in one of two ways. For smaller trees we try to show an interactive representation, which allows you to select specific nodes in the tree and view them as an alignment or as a set of Pfam domain graphics.
Unfortunately we have found that there are problems viewing the interactive tree when the it becomes larger than a certain limit. Furthermore, we have found that Internet Explorer can become unresponsive when viewing some trees, regardless of their size. We therefore show a text representation of the species tree when the size is above a certain limit or if you are using Internet Explorer to view the site.
If you are using IE you can still load the interactive tree by clicking the "Generate interactive tree" button, but please be aware of the potential problems that the interactive species tree can cause.
Interactive tree
For all of the domain matches in a full alignment, we count the number that are found on all sequences in the alignment. This total is shown in the purple box.
We also count the number of unique sequences on which each domain is found, which is shown in green. Note that a domain may appear multiple times on the same sequence, leading to the difference between these two numbers.
Finally, we group sequences from the same organism according to the NCBI code that is assigned by UniProt, allowing us to count the number of distinct sequences on which the domain is found. This value is shown in the pink boxes.
We use the NCBI species tree to group organisms according to their taxonomy and this forms the structure of the displayed tree. Note that in some cases the trees are too large (have too many nodes) to allow us to build an interactive tree, but in most cases you can still view the tree in a plain text, non-interactive representation. Those species which are represented in the seed alignment for this domain are highlighted.
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Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.
There are 6 interactions for this family. More...
We determine these interactions using iPfam, which considers the interactions between residues in three-dimensional protein structures and maps those interactions back to Pfam families. You can find more information about the iPfam algorithm in the journal article that accompanies the website.
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the DNA_pol3_beta domain has been found. There are 183 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.
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text:
NEWARK, N.J. (AP) Chris Flores scored 32 points without missing a shot and became New Jersey Institute of Technology's career scoring leader Wednesday night as the Highlanders routed Fisher 108-69.
Flores, the leading scorer in the Great West Conference, established a career high of 32 points on perfect shooting. He was 11 for 11 on field goal attempts, 7 of 7 on 3-pointers and 3 for 3 at the foul line.
The last player to score at least 30 points while not missing a shot from the field and making at least seven 3-pointers was Oregon's Bryce Taylor. He had the same scoring line as Flores on March 10, 2007.
Flores surpassed Isaiah Wilkerson, who finished with 1,577 career points last season, as NJIT's career scoring leader in its seventh year in Division I. Flores now has 1,604 points.
Tyler Shular led Fisher, an NAIA D-II college from Boston, with 22 points.