In most of the power electronics converters, the overall footprint and profile of the whole system are in large part determined by the footprint and profile of the passive components and the interconnections between them. Integrated magnetics, planar magnetics and passive integration techniques have been topics of research for the past few years to reduce the parts count, footprint and profile of the passive components, hence increasing the power density of the whole converter. This becomes especially prominent in the distributed power system (DPS) front-end converters, as the trend is moving from 2U (1U=1.75 inches) standard toward 1U standard. This paper presents a comparative study of the integration steps of passive components of an asymmetrical half bridge circuit (AHBC) for DPS front-end DC/DC converter application. Four AHBC converters using discrete passive components, nonplanar integrated magnetic components, planar integrated magnetic components and passive integrated power electronic module (IPEM), respectively, are constructed and tested. Comparisons are made from the viewpoints of volume, profile, efficiency, EMI and thermal performances of the four converters. The experimental result shows that the passive IPEM, which integrates all the passive components, has much higher power density, lowest profile, lower temperature rise and similar efficiency.


Abstract : For most of the tank projectile test firings, sky screens are used to obtain the flight time as a function of range. These range data can be used to extract muzzle velocity, velocity decay, and drag coefficient. An analysis and associated computational technique were developed to extract muzzle velocity, velocity decay, and drag coefficient from the sky screen data. This technique uses the advantage of a closed form solution to the equation of motion for a flat fire antitank projectile. The only limitation of this technique is that the drag coefficient must be a linear function of velocity. However, the results show that this technique obtains excellent velocity decay even with slight nonlinearity in the drag coefficient.


Farmers' income is a good indicator of farming feasibility through the large ratio of income to farm costs. The income of rice farmers also has an impact on the level of poverty and household food security of farmers, which is related to the ability of farmers to meet food needs based on the income received from rice farming. This research was conducted using a survey method through qualitative and quantitative approaches. Determination of the location and research respondents was carried out deliberately by the method of purposive sampling method in 1 (one) farmer group totaling 20 farmers (heads of families). The results showed that the amount of production, price, cost, and income of rice farming would affect the income and farm feasibility index. The feasibility ratio of more than 1 (2,34) indicates that rice farming has a comparative advantage, but the feasibility value has not been able to lift rice farmer households from poverty. The average rice farmer household in the Labuan Toposo Village is in the criteria of "Poor" households with a household income equivalent to a value of between 240-320 kg of rice/person/year. However, even though the farmer's family is classified as poor, by having a side business, the average farmer household can have food security from a side business by raising livestock and utilizing the yard by growing vegetables and fruit, taking non-timber forest products such as rattan and honey.


a Department of Physical Chemistry, University of Málaga, Campus de Teatinos s/n, 229071, Malaga, Spain. b Department of Chemistry, University of Reading, Whiteknights, Reading RG6 6AD, United Kingdom. c Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. d Department of Physical Chemistry, University of Alicante, E-03080 Alicante, Spain


This study presents results from the first systematic botanical investigation of the RPPN Feliciano Miguel Abdala (RPPN-FMA, formerly Caratinga Biological Station), a semi-deciduous forest fragment in southeastern Brazil that supports nearly a third of the remaining population of the critically endangered northern muriqui ( Brachyteles hypoxanthus ). Here we describe the structure, diversity, and floristic composition of this forest. Our goal was to provide the scientific basis for a management plan that will take into consideration the factors involved in the unusually high muriqui carrying capacity in this fragment. Our sample comes from six 500 x 10-m plots, totaling 3 ha. We marked and identified all trees with DBH ≥ 10 cm in all of the plots, and all trees of 5 ≤ DBH <10 cm in half of the plots (1.5 ha). Forest structure was consistent with secondary forest characteristics, inasmuch as large trees were rare, total basal area was small, canopy was discontinuous, average tree height was low, and liana load was heavy. Top-ranking families, based on Importance Value, were Fabaceae, Euphorbiaceae, Annonaceae, Rubiaceae, and Moraceae. Compared with other forests where northern muriquis occur, the RPPN-FMA forest was more floristically diverse (H' = 4.6) and even ( J = 0.85). In addition, top- ranking species were known muriqui foods. These factors might contribute to the unusually high density of the primate found at this site.


We present the first monolithic integration of mierolensed high-performance substrate input/output vertical-cavity lasers (VCLs) and resonant photodetectors that are compatible with flip-chip bonding.


Literature, painting and cinema convey different perceptions of the extravagant experience of madness. This article analyses some examples of each of these manifestations, such as excerpts from the narrative work of Julio Dinis, a 19th century Portuguese writer, paintings by Robert-Fleury Tony and Gericault, dating from the same period, and finally the film A Beautiful Mind (2001), offering a Foucaultian view on this matter. The works of Michel Foucault, The hermeneutics of the subject (2006) and History of madness (2005), allow addressing "the self-care" in a power-knowledge-freedom relationship axis as well as the importance that the awareness of the self, of others and of the world has in the process of creating their ethical existence, regarding the never completed transformation of the subject. The aim is also to ascertain to what extent each of these art forms reveals Foucault's theoretical assumptions.

Keywords: madness, dinisiana's narrative, painting, cinema, Foucault


The lack of spatial information about the number, location, frequency and spatial extent of wildfires in the tropical savannas region of northern Australia has lead to the progressive development of an operational system for the routine mapping and monitoring of fire using the NOAA series of polar orbiting satellites.


Congenital chordee unlike acquired one has a number of peculiarities that should be taken into account when making a diagnosis and performing surgical treatment. There are also differences in determining the indications for surgery and managing the early and late postoperative period in these patients. The surgical treatment was analyzed in 24 patients. Particular importance is attached to the diagnosis of this pathology using a vacuum-compression device and to the feature of its application in the early postoperative period after different surgical interventions for congenital penile deviation. Considering that fact that there are few publications on the analysis of surgical treatment for congenital penile deviation in the literature references, we decided to share our observations. The main objective of this investigation was also to study early and late complications after different surgical treatments for congenital chordee and to show our experience in their management using local negative pressure therapy.


In response to a task-relevant and improbable signal, a series of "endogenous" potentials related to the perceptual detection of the stimulus can be recorded from the human scalp in addition to the "exogenous" or stimulus-bound evoked potentials. (Donchin et al., 1978). The most prominent of these potentials is the late positive component, P3 or P300, that is maximally recorded from the centroparietal scalp. On the basis of this scalp distribution it has been suggested that the P3 wave is generated in the parietal association cortex (Vaughan and Ritter, 1970; Simson et al., 1976; Picton et al., 1978; Vaughan et al., 1980). The endogenous components of the human evoked potential have been recorded recently from depth electrodes placed in the brains of epileptic human patients. Wood et al. ( 1 980) recorded from multiple-contact electrodes directed toward the temporal lobes from frontotemporai and parieto-occipital locations. They found that there was no phase reversal of the P3 across the cortex, that the endogenous components were recorded with maximum amplitude subcortically, and that there was a shifting of peak latencies between the different recording locations on the electrode. These results suggested the possibility of multiple generators-perhaps both cortical and subcortical. Halgren et al. (1980) have recorded from depth electrodes placed in the hippocampus and amygdala. Large event-related potentials (ERPs) occurred in these areas a t the same time as scalp-recorded endogenous potentials and with similar relationships to attention and to probability. These potentials reversed in polarity over small distances and were associated with concurrent changes in unit activity. These results indicated definite neural activity in the limbic system during the scalp-recorded endogenous potentials, but left open the question whether part of the scalp-recorded activity is volume-conducted from the limbic system. Nasopharyngeal electrodes are used in clinical electroencephalography to record from the mesial surface of the temporal lobe (Mavor and Hellen, 1964). Smith et al. (1973) have reported that the Ni and P2 of the vertex potential are recorded with opposite polarity from nasopharyngeal electrodes referred to a balanced noncephalic reference (Stephenson and Gibbs, 1951). On recordings taken between the ear and nasopharynx (Peters and Gibbs, 1973), however, the only definitely recognizable evoked potential was a small ear-negative wave occurring about 35 ms later than the Ni peak at the vertex. It is possible that the nasopharyngeal recordings might allow an evaluation of limbic activity during normal human cognition. We therefore decided to record from nasopharyngeal electrodes the ERPs associated with the detection of improbable target stimuli.


The recent change of social environment has influence on the configuration of space for the social welfare center. And so the relation of space and function required the change of spatial configuration. The social welfare center fills the role of family welfare, domiciliary care, community organization etc. In such sence, this study explore the conditions of spatial configuration for the domiciliary and community care unit of social welfare centers in small city. For this study, it was investigated the space role and funtion, the service program, the usage characteristics, the room satisfaction of social workers. In sum, the useful data were collected, analyzed, and colligated by case study. It could be used in the design criteria of domiciliary care unit for the social welfare center in small city.


According to the Environmental Protection Agency (EPA), over one-third of food produced in the U.S. goes to waste. With 24% of the waste ending up in landfill and 22% incinerated, this contributes to greenhouse gas emissions and climate change. Since 2014, MGH has partnered with Agri-Cycle to divert food waste from Eat Street Café to an anaerobic digestion facility for generation of energy. In 2020 alone, 523 tons of diverted food waste generated an amount of energy equivalent to what is needed to power 50 homes. Nurses in Perioperative Services, in collaboration with Environmental Services, are now expanding the Food to Energy program, starting with the Gray 4 employee kitchen area. Next steps in this nurse-led initiative will be to promote education about the Food Recovery Hierarchy and the importance of a Zero Waste Boston.


In physics, momentum is one of the most fundamental properties. The law of conservation of momentum is universal. According to the special theory of relativity, light has momentum despite the fact that a photon has no mass. This claim is very surprising, for how can something without mass have momentum? From Newton's second law of motion, we know that something that has momentum can exert a force. So can light exert a force? If so, can we measure it? This article describes a first-year physics project to measure the force exerted by light and thus show that light does indeed have momentum, conducted by Kjeld Bak, Christian Prag and myself in the spring of 2008, under the guidance of Ian Bearden and Mogens Levinsen. We constructed a torsion pendulum in a vacuum chamber and fired a powerful laser at a mirror attached to the pendulum. The pendulum rotated away from the laser light and we could measure the force of the light by the angle of deflection. By using a second laser to measure the angle of deflection and a photosensor attached to a computer, we could see the effect of light on the pendulum in real-time, and were able to record precise data about its motion. The results were very encouraging. We were able to both visibly see the effect of light on the pendulum and measure a force in the order of 10−9N. The measured force was within 6 % of that predicted by theory.


This paper makes an analysis of the course characteristics of Image Transmission and Procession and makes a summary of three years′ teaching experiences.The significance of applying multimedia in this course is discussed,and teaching methods about computer programming are introduced.These prove that it is necessary to combine theories and practices,and foster students′ abilities to apply theories to solve real problems in order to realize the targets of developing practice-oriented undergraduate talents.It is indispensable to pay attention to both theories presentation and their real applications.


Abstract We review potential mass-loss mechanisms in the various evolutionary stages of massive stars, from the well-known line-driven winds of O-stars and BA-supergiants to the less-understood winds of Red Supergiants. We discuss optically thick winds from Wolf-Rayet stars and Very Massive Stars, and the hypothesis of porosity-moderated, continuum-driven mass loss from stars formally exceeding the Eddington limit, which might explain the giant outbursts from Luminous Blue Variables. We finish this review with a glance on the impact of rapid rotation, magnetic fields and small-scale inhomogeneities in line-driven winds.


Aiming at the existing heavy-haul railway, bridges hardly meet the transportation requirements. Based on the spatial vibration calculation model of the freight train–track–bridge (FTTB) system, the FTTB spatial vibration model under the condition of auxiliary steel beam reinforcement is established. Besides, according to the random analysis method of train derailment energy, coming up with an evaluation method of auxiliary steel beam reinforcement is based on safety and dynamic response, which is used to discuss the train safety and the change law of FTTB system vibration response. The results show that the derailment resistance of the FTTB system is increased by 22.6% after the auxiliary steel beam is reinforced. Compared with the previous speed (115.56 km/h), the speed is 132.73 km/h after the auxiliary steel beam reinforcement; at the same time, the allowable limit speed increases from 92.49 km/h to 106.18 km/h. In addition, the reinforcement of the auxiliary steel beam can not only effectively reduce the lateral vibration response of the FTTB system under the action of empty wagon but also effectively decline the vertical vibration response of the FTTB system under the action of the loaded wagon, which can meet the stability requirement for running at the speed of 90 km/h. In summary, the reinforcement of auxiliary steel beams can improve the running safety of trains, reduce the vibration response of the FTTB system, and meet the requirements of operation stability.


In construction machinery, engineering, aircraft engineering, space technology and other branches of the national economy there are problems of studying the stress-strain state of plates, membranes and rotating membranes. The main load on the elements of such systems is the significant centrifugal forces of inertia, which significantly affect the strength characteristics of structures. In many cases, the axis of rotation of mechanical systems can make a turn, which leads to the emergence of not only portable and relative, but also coriolis forces of inertia, which change periodically over time. The gyroscopic interaction between the rotational motion of the system and the relative elastic oscillations of the elements is a source of excitation of precessional oscillations that can be resonant or unstable. As a result of changing the orientation axis of the system, the gyroscopic moment causes the appearance of alternating stresses, which significantly affect the strength and reliability of the structural elements. In the works [1, 3-10] the stress-strain state and oscillations of membranes, plates and shells carrying complex motion in the central force field are investigated. In this paper, the relations that determine the stress-deformed state of the system of two closed conical shells connected by a central rigid insert, which rotates with a constant angular velocity around the axis of symmetry of the system, whose center of mass moves in the central force field are given.


The bimetallic complexes CpRu(P−P)X [Cp = η5-C5H5; X = Cl, H; P−P = dppf (1,1′-bis(diphenylphosphino)ferrocene), dppr (1,1′-bis(diphenylphosphino)ruthenocene), dppo (1,1′-bis(diphenylphosphino)-osmocene), dippf (1,1′-bis(diisopropylphosphino)ferrocene), dcpf (1,1′-bis(dicyclohexylphosphino)ferrocene)], Cp*Ru(P−P)X [Cp* = η5-C5Me5; X = Cl, H; P−P = dppf, dippf, dppomf (1,1′-bis(diphenylphosphino)octamethylferrocene), dppc (1,1′-bis(diphenylphosphino)cobaltocene)], [Cp*Ru(P−P)X]+ (X = H, CCPh; P−P = dppc+), and [Cp*Ru(P−P)L]2+ (L = CH3CN, t-BuCN; P−P = dppc+) have been synthesized. Most of the chloride and hydride complexes have been studied by cyclic voltammetry. The X-ray structures of [Cp*Ru(dppc)CH3CN][PF6]2 and [Cp*Ru(dppc)CCPh][PF6] have been determined. Protonation of [Cp*Ru(dppc)CCPh]+ gives the vinylidene complex [Cp*Ru(dppc)CCHPh]2+. The Co(III/II) potential of the dppc+ ligand undergoes a cathodic shift upon coordination in [Cp*Ru-(dppc)H]+ and an anodic shift upon coordination in [Cp*Ru(dppc)CH3...


Gastric cancer mesenchymal stem cells (GC‐MSCs) can promote the development of tumour growth. The tumour‐promoting role of tumour‐associated MSCs and T cells has been demonstrated. T cells as the major immune cells may influence and induce a pro‐tumour phenotype in MSCs. This study focused on whether CD4+ T cells can affect GC‐MSCs to promote gastric cancer growth.


Scene analysis is reformulated within sateliもかroadway-vehiclenetwork. For integrating multi-viewpoint imagery, randomness underlying natural complexity is extracted and associated with fractal version of maneuvering affordance. Scale shift due to perspective projection is evaluated for separating the image of not-yet-identifed object from the maneuvering affordance. 1 Introductory Remarks Computational resources combined with advanced mechanical systems rapidly expands the scope of 'informatic vicinity [15]' in which the transition to fatal situation is charged to human's decision. For instance, students knowledge can be expanded interactively by space craft to be operated仕omclassroom [4]; final decision for social safety in large scale natural disaster is missioned to the governorship of information gathering and damage evaluat町 1systems [6]; the mobility 0 ぱfc∞om pu七ercontrolled vehicles should be unified wi泊thinhuman' 、sinherent perceptio ∞n 任lト-deci凶s剖ioncapabi出lityi 凶nthe s 幻i t ιuatiωi ぬon七 ωobe encountered [22 司].In these human centered systems, the perception process is exposed to risky situation; subsequent maneuvering processes is anticipatively activated in unstructured scene. Expanded vicinity, thus, should be supervenient to the real world邸 possibility graph spanning not-yet-identified objects Three decades of investigations in neurophysiology reveals that the consciousness of perception-decision o 0.5 0.65 1 sec. physical time Figure 1: Mental Expansion Figure 2: Cooperative Decision in Informatic Vicinity linguistic logical-mathematical spatial body-kinesthetlc Scene Horizon of Anticipation


As a pre-study for researches on powering characteristics of straight-framed V-bottom hull forms for usual commercial vessels, practicability of such a hull is investigated from viewpoints of over-all ship economy. For this purpose, a trawler hull of straight-elements with double chines, SV(T)-1, similar to Prof. Nevitt's W-8 in size and hull form coefficients was designed and tested at the SNU Ship Model Towing Tank for resistance measurements. The result is given in Fig.3 together with those of W-8 and other equivalent hulls of double curvature, such as FAO 135a-173, Doust and Takgi. The curves of the latters are reproduction of Prof. Nevitt's analysis, and given for comparison purpose. With in speed range of konts the resistance coefficients of SV(T)-1 are higher than those of W-8, and and higher than those of FAO 135a-173 and Doust respectively. SV(T)-1, however, is slightly superior in resistance characteristics than Takagi's equivalent hull within the speed range. On the other hand, an equation for reduction rates of hull construction cost required to compensate for propulsion power increase in straight-elements hulls was derived from the definition of the economic efficiency of commercial vessels. The solution of the equation is given in Fig.4 graphically, from which it is known that increase in propulsion power can be compensated by reduction in hull construction cost. Considering simplicity and less equipments required in construction of straight -elements hulls, the author does argue for attainability of the above reduction rates in hull construction cost. Consequently, it is concluded that there is clear feasibility to adopt straight-elements hulls for usual commercial vessels of medium and small-size. And a further research will be done to obtain reliable data for chine shapes having good flowliness with the flow around ships depending on ship's size and speed.


Art Nouveau, which means 'new art' in French, is a trend that became popular in the late 19th and early 20th centuries, characterized by the use of curvy lines, intense plant motifs and elegant animal patterns in art and design. In this study, the artistic understanding of the Mir iskusstva / World of Art school consisting of the Russian representatives of the Art Nouveau movement and their magazine was discussed. Art Nouveau representatives have agreed on basic aesthetic values in different countries. However, it is inspired by local elements in search of preserving national values, bringing together traditional lines of art with modern lines. In this study, it is concluded that this initiative in Russia originated a separate style, which is called 'Russian style'.


Librarianship, archives management, and records management have functioned largely as autonomous disciplines. Economic, technological, and higher-education trends, however, mitigate against continued ― possibly self-defeating ― claims to uniqueness. A growing number of observations in the literature about interfield relationships, pressing long-term economic and higher-education realities, and a distinct language shift in the Standards for Accreditation, 1992, toward greater inclusiveness encourage examination of shared conceptual characteristics among the information fields. Areas of convergence include the information life-cycle concept, gatekeeping, information storage and retrieval, information representation, assistive/instructional roles, ethics, and custodial/preservation concerns. Implications for education and research in an emerging unified field of information management or information studies are suggested.


The thesis compares Argentine and Australian fiscal systems from the late nineteenth to the late twentieth centuries. It uses institutionalist and endowments approaches to evaluate the importance of state credibility and taxation on long run economic development. After rapid convergence in the early twentieth century, Argentina and Australia clearly diverged in the latter twentieth century. Divergence emanated from different institutional experiences, which ultimately originated from dissimilar experiences of state credibility. State credibility is the extent to which society trusts the state to act in its interests. Fiscal institutions are a clear and comparable measure of state credibility over time as they frankly express underlying political economy. As Argentina and Australia were once similarly successful settler economies with comparable geographic prospects for development, the comparison promises to transcend geographically deterministic explanations for development. Geography primarily consists of factor endowments and location. In fact Argentina was better placed to succeed in geographic terms than Australia. Yet Australia, not Argentina, secured the status of a developed country. Australia and Argentina exemplify the relative insignificance of geography in shaping development. Divergence resulted from a failure of Argentine institutions to generate sufficient space for negotiation and compromise, and a 'latent civil war' was entered from the 1930s until the early 1980s. A key finding of the thesis is that divergence in fiscal institutions, especially differing capacities to embed progressive systems of direct taxation was crucial to divergence in development. This finding is based upon the discovery of new evidence and the harmonisation of fragmented time series which enable comparison over a long period of time. Argentina and Australia took different paths in the latter half of the twentieth century due to distinct institutional environments and their legacies for social consensus and development.


We have fabricated fiber‐compatible, low‐loss, wavelength and polarization insensitive 3 dB 2×2 cross couplers by Ag+‐Na+ ion exchange in glass. The couplers were designed using the adiabatic invariance condition for graded‐index channel waveguides. An excellent agreement between theory and experiment is demonstrated.


Introduction: Inferior alveolar nerve is responsible for the sensory innervation of the mandible and its teeth. Knowledge about the exact location of mandibular foramen is very important due to its important role in the success of mandibular block injection and possibility of nerve injuries during oral and maxillofacial surgeries. The aim of this study was to evaluate the accuracy of panoramic radiographs in determining the location of mandibular foramen. Materials and Mmethods: In this random cross-sectional study 50 panoramic and lateral cephalometric radiograms were collected from patients, 20‒50 years of age, referring to Afzal Dental Clinic in Esfahan in spring 2012. Measurements were taken by a caliper from the center of the foramen to the occlusal plane and anterior border of ramus. Data was analyzed by t-test and intraclass correlation coefficient (ICC) using SPSS 11.5 (α=0.05).  Results: According to t-test, mean distances from the center of the foramen to the occlusal plane (p value = 0.04) and to the anterior border of ramus (p value < 0.001) on panoramic radiographs were significantly greater than the actual distances measured on lateral cephalograms. In addition, there were similarities between the distances from the mandibular foramen to the occlusal plane (p value < 0.001, r = 0.8315) and the anterior border of ramus (p value < 0.001, r = 0.9126) on panoramic radiographs and the actual distances measured on lateral cephalograms. Discussion: Under the limitations of the present study, it can be concluded that measurements on panoramic radiographs are similar to those on lateral cephalograms in both anteroposterior and vertical dimensions and on the condition that radiographic principles are observed they can be used to determine the location of mandibular foramen. Key words: Inferior alveolar nerve, Mandible, Panoramic radiography


Common, nonspecialized group-contribution and corresponding-state models for the estimation of normal boiling point, critical data, vapor pressure, liquid density, dynamic viscosity, and surface tension are reviewed in view of their application to fatty acid ethyl esters to provide guidelines for practical application of these models in process engineering. As a result, these properties can be estimated in a satisfactory manner when choosing an appropriate model, showing minimum average absolute mean deviations of the normal boiling point below 5 K (3.4 K for saturated and 4.2 K for unsaturated components), those of the critical temperature below 3 K (2.3 K for saturated and 1.2 K for unsaturated components), those of the critical pressure in the region of 50 kPa (54 kPa for saturated and 2.1 kPa for unsaturated components), and minimum relative mean deviations of saturation pressures from 2% around the normal boiling point to 15% at extremely low pressures, those of liquid density below 1%, those of visc...


Tliese periods cover different plhases of warfare and include periods of heavy fighting and of relative quiet. AWe liave included all cases of penetrating wounds of the chst admitted to the casualty clearing station, however serious the complications, and lhave excluded those cases of concussion haemothorax in which' the pleura had not be4n opened by the missile. IFor the analysis of cases and results, shown in the subsequent tables, we haveexcluded tlhe first tw6 periods because: 1. It is uncertain that all clhest wounds admitted to the casualty clearing stations were seen by us in -tlhose periods. 2. It is probable that thle more serious cases were diverted by the-field ambulances ahead of us to advanced operatinA 6centies. X-


As an efficient data fusion method, over-the-air computation integrates computation and communication by exploiting the superposition property of multiple access channels. In this paper, a framework on deep learning enabled over-the-air computation is proposed, where both the pre-processing and post-processing functions are represented by deep neural networks (DNNs). In this way, the over-the-air computation can approximate any function via learning through the data. The deep over-the-air framework is useful to a variety of machine learning applications on the Internet-of-Things (IoT). The experiments on distribution regression and anomaly detection have shown the effectiveness of the proposed method.


The background of pot as one of pottery development could be understood in two aspects: commerce, inter-cultural relations, and language. An enormous pot made from clay at Gedungkarya site is a new issue. Where this pot does came from? And, whether Gedungkarya site is an 'industry' or not? Hitherto the question still under debates for white clay pots distribution includes wide areas in South East Asia. A typology study to compare with South East Asia pots is an effort to answer the question above.


We present Monte Carlo calculations of lattice Abelian Higgs models in four dimensions and with charges of the Higgs particles equal to q = 1, 2, and 6. The phase transitions are studied in the plane of the two coupling constants considering separately average plaquette and average link expectation values. The density of topological excitations is studied. In the confinement phase we find finite densities of magnetic-monopole currents, electric currents, and vortex currents. The magnetic-monopole currents vanish exponentially in the Coulomb phase. The density of electric currents and vortex currents is finite in the Coulomb phase and vanishes exponentially in the Higgs phase.


This paper explores the sensitivity of electricity prices in energy-only markets with large amounts of wind and solar power. After electricity prices have fallen in many energy-only markets in recent years, the topic has been discussed in many studies with different approaches. The approach in this paper is to perform extensive electricity market simulations. The study is based on the North European power system, and it was carried out using a generation planning model to create reasonable capacity mixes for future, and a unit commitment and economic dispatch model to simulate electricity prices. The results show that the amount of base load generation capacity and overcapacity has a very high impact on electricity prices. The share of wind and solar power and the price of CO2 also have a clearly detectable, but less significant, impact.


Abstract The following Lytoceratinae are recorded from the Upper Jurassic of New Zealand. Heterian Stage (Lower and Middle Kimmeridgian):. Lytoceras taharoaense n. sp.; L. sp., cf. taharoaense, L. sp. indet. A, cf. taharoaense, L. sp. indet. B; and? Lytoceras sp. indet. Puaroan Stage (Tithon-ian): L. sp. indet. C;? Lytoceras sp. indet.; and cf. Lytoceratinae indet. Specimens assigned to L. taharoaense fall into three size groupings: small (diameter up to 170 mm), medium (diameter 435 mm), and large (diameter 1500 mm). Ribbing and whorl cross-section vary with size. The largest specimen of L. taharoaense is noteworthy for its large size (1.5 m diameter), completeness and degree of preservation, marked modification of ornament on the body chamber, and development of large lamellar flares close to the aperture.


There has been decline in the production of goat meat, pork and beef during the 1996-98 period. The basic constraining factor is increasing cost of production associated with feeds and accessibility of maize, which is the major component of feed. However provision of alternative or complementary feed component such as sweetpotato, which is cheaper and readily obtainable than concentrate, will enhance availability of quality feed to accommodate expansion of livestock. Five goats on extensive management were used for the study. Sweetpotao peels were fed to the animals. Peels weighing 8.3kg that were produced over night were sole fed to these animals. The goats were watched as the feed on them without any difficulty. After about a year the first treatment was done a local variety of sweetpotato were peeled and the peels (less than 8.3 kg) were given to a group of five goats (different from the first group) on the same day that they were peeled. They ate the entire sample given to them and they survived. After about one month the peels that were dried for three days were also given to the goats and they ate them with no difficulty. About three goats and some poultry birds were given toasted granules (Spari) and they also ate. Some pieces of boiled sweetpotato were also dropped for about four groups of goats and they ate them. Therefore there is an increasing potential in sweetpotato for both human and livestock consumption. This calls for agricultural extension agents to create awareness on the potentials of sweetpotato as it is easy to produce and cheap to buy. Also, it enhance the transfer of technology, not only for increase production but also on processing and consumption in diverse forms for diverse groups. African Journal of Livestock Extension Vol.3 2004: 33-36


The invention relates to a method for detecting the presence of objects (42) in a passenger compartment of a vehicle (43), wherein electromagnetic signals are radiated into the passenger compartment. The signals are reflected in accordance with at least one object property of at least one object (42) that is present in the passenger compartment. The reflected signals are received and are evaluated with regard to the at least one object property. The method is characterized in that the method is performed by a vehicle-to-X communication device (303) that communicates wirelessly. The invention further relates to a corresponding device.


1. Changes in strength of cotton, Italian ryegrass leaf, hay stem and barley-straw stem on immersion in the contents of the reticulo-rumen, at two sites in the rumen and at one site in the reticulum, for periods of up to 56 h were measured using a cow on a hay diet. Specimens of the fibrous materials were immersed in the rumen digesta in such a way that they were not damaged by agitation or by rumination. 2. Load-to-fracture and elongation were measured on a machine using a constant-speed cross-head at a strain of about 10−3/s. The ratio strength:density (breaking load/mass per unit length) was determined. 3. Leaf of Italian ryegrass and stem of hay and of barley straw had strengths of about 37, 150 and 210 MN/m2. They lost strength at different rates when immersed in the rumen digesta, the times to half strength being in the ratio grass: hay: straw = 1:1.9:3.8. The similarity of this ratio to that for total time for eating and ruminating as given by Balch (1969), namely 1:2.0:3.5, for similar materials was noted.


EDRS Price MF-$0.55 RZ-$3.29 *Adult Education, *Functional Illiteracy, *International Programs, *Literacy Education The meeting reported upon was held to review existing cooperation between the United Nations Specialized Agencies in the field of literacy, as well as to discuss future collaboration in the light of the 1971-1972 P,:gram and Budget of UNESCO and the orientation and expansion of the Wocld Literacy Programme proposed therein. The report covers the meeting agenda as follows: (1) General Review of. Activities in 1970; (2) Inter-Agency Cooperation in the Future Programme; (3) Regional Centre for Functional Literacy in Rural Areas for the Arab States (ASFEC) and the Regional Centre for Functional Literacy in the Rural Areas of Latin America (CREFAL); and (4) Research and Diffusion of Information. A list of participants is given as Annex I. (Author/U3) Distribution: limited U S DEPARTMENT OF HEALTH, EDUCATION I WELFARE OFFICE OF EDUCATION THIS DOCUMENT HAS BEEN REPRO DUCED EXACTLY AS RECEIVED FROM THE PERSON OR OPGANI2ATION OPiG INAING IT POINTS OF Vk:LN OR OPIN IONS STATED DO NOT ESSARILY REPRESENT OFFICIAL OF OF EUU, CATION POSITION OR POLICY ED/WS/206 PARIS, 15 January 1971 Original: English UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION INTER-AGgICY MEETING ON WORK-OPTENTED LITERACY Unesco House, 1-2 December 1970


The air-entrained can have much effect on each performance of concrete, pouring of the air-entrained in concrete will make the space smaller, each stere will have several hundreds million of minuteness, stable distributing and non-connection air bubble. These bubbles enlarge the content of the granule in mixture concrete. Furthermore, thanks to the strength of surface of the minute air bubble, it can work like the ball bearing in the concrete mixture, pour, smash and improve the fluidity. The non-connection bubbles are also helpful to the freezing of the concrete. Based on the problems in slip-form construction and a number of data from home and abroad, the article analyses the material, thick and thin collective stuff, the effect of the cement, the facture and the slip-form technology of the concrete.


The rapid growth of the world's population has put significant pressure on agriculture to meet the increasing demand for food. In this context, agriculture faces multiple challenges, one of which is weed management. While herbicides have traditionally been used to control weed growth, their excessive and random use can lead to environmental pollution and herbicide resistance. To address these challenges, in the agricultural industry, deep learning models have become a possible tool for decision-making by using massive amounts of information collected from smart farm sensors. However, agriculture's varied environments pose a challenge to testing and adopting new technology effectively. This study reviews recent advances in deep learning models and methods for detecting and classifying weeds to improve the sustainability of agricultural crops. The study compares performance metrics such as recall, accuracy, F1-Score, and precision, and highlights the adoption of novel techniques, such as attention mechanisms, single-stage detection models, and new lightweight models, which can enhance the model's performance. The use of deep learning methods in weed detection and classification has shown great potential in improving crop yields and reducing adverse environmental impacts of agriculture. The reduction in herbicide use can prevent pollution of water, food, land, and the ecosystem and avoid the resistance of weeds to chemicals. This can help mitigate and adapt to climate change by minimizing agriculture's environmental impact and improving the sustainability of the agricultural sector. In addition to discussing recent advances, this study also highlights the challenges faced in adopting new technology in agriculture and proposes novel techniques to enhance the performance of deep learning models. The study provides valuable insights into the latest advances and challenges in process systems engineering and technology for agricultural activities.


This work is part of current research focused on private higher education in Mexico, under an economic sociology approach of the education market and territorial integration. The paper focuses on four key topics: the current characteristics of growth and supply of private higher education; the forms that its territorial distribution in the country adopts; some general features of the economy of private higher education as the business size in the national economy and the price structure; and the relationship between changes in the regulatory environment and strategies of private institutions to gain social legitimacy and competitiveness.


Cyberbullying is direct action harassment that negatively impacts everyone involved. As a societal concern, cyber-attacks and cyberbullying as a threat remains largely unsolved. Due to the challenging nature of the growing intersectionality between perpetrators, victims, and society, cyberbullying disproportionately affects marginalized individuals and adolescent age children, and continues to have a detrimental impact on juvenile victims, their friends, families, and academic institutions. As a threat, cyberbullying has become weaponized by attackers to target and inflict maximum pain and suffering on victims based on a variety on individualistic differences, including varying social identities, race, age, sexual orientation, ethnicity, gender, and social status. To ensure attack success, the bully in a cyber-attack (cyberbullying) will introduce a series of prolonged, continuous procession of abuse designed to inflict adverse effects on the physical, psychological, and mental health of the victim.Long-term abuse suffered as a direct result of a cyberbullying attack has led to irreparable mental health concerns, challenges in classroom and work activities, victim self-harm, and tragically suicide, regardless of victim age. This unfortunate realization highlights the need for more work to be done to protect our youth. Moreover, the continued misidentification, misclassification, and incorrect definition of what is a cyberbullying attack has led to inadequate and inefficient implementation of effective training solutions and prevention policies to designed to combat cyberbullying concerns, leading to a significant negative impact on victims' overall mental health, well-being, and quality of life.


Summary
Calibrations enabled controlled application of a range of known dispersive energies to a selected soil sample. The corresponding levels of dispersion were measured in terms of the weight fraction of particles <2 μm equivalent spherical diameter produced, and are used to define a dispersion characteristic for the test soil.

Interpretation of this characteristic in terms of a microaggregate theory provides the energy value associated with complete 'primary dispersion' of microaggregates, which under normal field conditions is a direct practical measure of soil stability. This leads to a definition of the specific stability index (σ) of a soil which for the gleyed brown earth used in this work has the value (25±3) J g−1.


Thank you very much for downloading anti immigrantism in western democracies statecraft desire and the politics of exclusion. Maybe you have knowledge that, people have look numerous times for their chosen readings like this anti immigrantism in western democracies statecraft desire and the politics of exclusion, but end up in harmful downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they cope with some malicious bugs inside their laptop.


The Lepidoptera faunas of the remote Pacific islands, Easter, Pitcairn and Henderson, are listed and discussed, with notes on biology. They are compared with the faunas of Mururoa and Rapa Islands, the five islands providing contrasts in geology, ecology and human disturbance. A new hawk moth is described, Hippotion hateleyi, endemic to Henderson Island.


M rocketry provides the scientist with a powerful tool for probing mysteries of nature heretofore inaccessible to man. Starting with vertical rocket launching, followed by placing artificial satellites in orbit with the aid of rockets, and finally launching cosmic rockets for the investigation of cosmic space in the vicinity of the moon. Soviet scientists obtained within slightly more than a decade substantially new data on the properties of the Earth's upper atmosphere, on the phenomena that take place there, on the composition of cosmic radiation, and on the properties of interplanetary matter. As is known, the research performed to date culminated in the first photographs of the dark side of the moon.


In another contribution we presented numerical simulation results of LAPLAS implosion [1] that uses an annular beam focal spot to drive the target. In the present contribution we report similar results that have been achieved using a circular focal spot. The rest of the beam parameters and the target parameters are the same as in the other case. The transverse intensity distribution in the focal spot is cons idered to be Gaussian with a FWHM = 1.5 mm. Different values of the beam intensity, N, including, 10 , 3 × 10 and 5× 10 ions per bunch, respectively, have been considered. The results are presented in Figs. 3–1, respective ly where we plot the density, temperature and pressure vs radius at the middle of the cylinder (L=3.5 mm) at the time of maximum compression in the water region. These simulations been carried out using a 2D hydrodynamic code, BIG2 [2]. For water and tungsten, we use the equation-ofstate (EOS) data reported in [3] and [4], respectively.


There was significantly correlation between soil salinity in intertidal zone obtained by mass method (the ratio of mass of water to soil is 5∶1) and electric conductivity of extracting solution diluted five times by electric conductivity method The relative errors were almost below 5% between soil salinity measured by the mass method and the ones calculated by electric conductivity. So, electric conductivity method is a simple and rapid method for measurement of soil salinity in intertidal zone after defining the regression equation between soil salinity and electric conductivity. Plenty of time can be saved by electric conductivity method when soil samples are excessive.


Abstract : This report investigated fundamental aerothermal phenomena in hypersonic flow, with particular emphasis on viscous/inviscid interaction phenomena. The experimental studies were conducted to examine the changes in the structure at the base of a hypersonic turbulent boundary layer as it is subjected to a strong self-induced pressure gradient in regions of shock wave/ boundary layer interaction. The initial phase of the theoretical program was directed toward summarizing existing techniques for obtaining Navier/Stokes solutions for laminar flow over flat plates in hypersonic flow. In the experimental program, surface and flow field measurements were made to examine the detailed flow mechanics associated with turbulent boundary layer separation over a large cone flare model at Mach numbers 11, 13 and 16 and Reynolds numbers up to 100 million. Holography measurements were used to examine the flow field regions of hypersonic shock wave/turbulent boundary layer interaction. In this preliminary investigation of the application of holography in a 96 inch Shock Tunnel, holographic interferograms were obtained for viscous/inviscid interactions at Mach numbers 11 and 13 and Reynolds numbers up to 30 million, nominally. Flow field studies were made for flat plate/wedge, cone/flare and incident shock configurations. The quantitative results presented offer new information as well as a potential to obtain density measurements in other types of hypersonic flow; however, they also reveal important concerns which need to be resolved before the interferometric data can be claimed to give accurate measurements of these flows. Two appendices include an invited review paper on aerothermal problems associated with hypersonic flight.


The ludic dimension of Bruno Munari's prolific children's book publishing activity plays an important role, as far as narration and visual arts are concerned. Since the 1940s, and for the following 50 years, books, play and education were fundamental reference points in the artistic production and critical thinking of this Milanese artist. Munari cultivated these influences with extraordinary results in his picturebooks. The following analysis of some of Munari's texts offers a historical-critical perspective on the value, function and representation of play in this vast production. The present research relies on three main analytical categories: co-authorship, disorientation and the experience of the limit.


The history of synovectomy shows that this procedure has had a gradual growth over a period of fifty years and that many surgeons in different countries have contributed to its evolutionary development.

Judging from the author's personal experience and the extensive literature of the past fifteen years, the operation seems to have established for itself a field of usefulness in various kinds of joint disease.

The consensus of opinion is that synovectomy may well be employed in a joint in which extensive induration and fibrosis of the capsule, enlargement of the synovial villi, and persistent increase of joint fluid are present. Such a joint may be caused by:


There is increasing evidence suggesting a discrepancy between the cosmic dipole observed in the number count of distant galaxies and the one derived from the cosmic microwave background (CMB). In this study, we investigate the possibility that the cosmic dipole problem can be addressed by considering the QCD axion, a hypothetical particle that arises from the spontaneous breaking of the Peccei-Quinn symmetry and is postulated to constitute the dark matter in our universe.


vs. 74.6%, p<0.001), dyslipidemia (39.3% vs. 71.9%, p<0.001) and type 2 di- abetes (3.2% vs. 28.1%, p<0.001) were less prevalent. Group 1 patients had lower HDL (33±3.6 vs. 39.5±11.3 mg/dL, p<0.05), fasting glucose (96.4±9.1 vs. 137±66 mg/dL, p<0.001) and oral glucose tolerance test (142.2±24.9 vs. 174.8±53.1 mg/dL, p<0.05). Hemoglobin (14.6±1.6 vs. 13.4±1.9 g/dL, p<0.005) and platelets levels (263.8±86.5 vs. 218.9±67.9 x109/L, p<0.05) were higher. In group 1, 83.3% of patients were submitted to angiography, that revealed a numer- ically higher prevalence of coronary arteries with non-significant stenosis (30% vs. 17.9%, p=0.08) and single-vessel disease (60% vs. 36.4%, p<0.05). The clin- ical risk of the patients, as assessed by the GRACE (99.6±21.3 vs. 135.9±32.9, p<0.001) or the TIMI (1.5±1 vs. 2.55±1.4, p<0.001) risk scores, was lower. No intra-hospital deaths were recorded in this group (0% vs. 5.8%) and follow-up all-cause mortality was also lower (2.9% vs. 19.6%, Log-rank p<0.05). Conclusions: Patients up to 35 years old diagnosed with ACS have a specific risk profile and have lower short term and long term mortality.


This review provides a brief overview and identifies some issues (a personal reading as always) which are explored in more depth within this book relating to mathematics teacher education. The symposium on which these proceedings are based was held in response to significant changes in the teacher education systems within Norway and Sweden. The changes represented attempts to address issues of recruitment and retention from the government perspective and issues of teacher quality and enhanced children's learning of mathematics from an academic or professional perspective. While the conversations developed from the local situation the similarity of the concerns internationally is clearly evident. The symposium set out to examine mathematics teacher education considering three main themes: (a) student teachers' motivation and mathematical competence to become teachers of mathematics with the ability to engender 'joyful learning' of mathematics; (b) the nature of the education necessary for both the student teachers and the mathematics educators, particularly with respect to the level and nature of mathematical knowledge they require; and (c) the extent and nature of links between theory and practice for both mathematics educators and teachers of mathematics. The book initially presents the background to the symposium and commentaries on it followed by a series of individual presentations. Next comes a distillation of a series of group discussions, a synthesis and panel discussion of these and lastly a reflection on the symposium as a whole. Here, following the order of the book, I will highlight some key aspects from some individual presentations and only briefly discuss other parts. The first several sections deal with the background to changes in Sweden and Norway, reactions to the issues raised with commentary from four international experts who developed four areas for consideration and then each took a different perspective to comment on. Barbara Jaworski discusses the 'joy' of mathematics, creating appropriate mathematical challenge for learners, the ways of knowing mathematics that teachers need, and the relationship between R. Strässer, G. Brandell, B. Grevholm, & O. Helenius (Eds.) (2004), Education for the Future. Proceedings of an international symposium on Mathematics Teacher Education.


We introduce a general setting for information elicitation in multi-agent systems, where agents may be approached both sequentially and simultaneously in order to compute a function that depends on their private secrets. We consider oblivious mechanisms for sequential-simultaneous information elicitation. In such mechanisms the ordering of agents to be approached is fixed in advance. Surprisingly, we show that these mechanisms, which are easy to represent and implement are sufficient for very general settings, such as for the classical uniform model, where agents' secret bits are uniformly distributed, and for the computation of the majority function and other classical threshold functions. Moreover, we provide efficient algorithms for the verification of the existence of the desired elicitation mechanisms, and for synthesizing such mechanisms.


The aim of this study is to find out which factors influence the area of agricultural land use in Central Java. This becomes important because the agricultural sector is a strategic sector, plays an important role for the economy and makes a big contribution to employment. This study uses per capita expenditure, total population, number of poor, number of industries and level of education as independent variables. By using data from the Central Statistical Office, the Ministry of Education and Culture, the Ministry of Agriculture and other relevant government agencies.
This study was conducted using panel data in 29 districts and 9 cities in Central Java over a period from 2015 to 2017. The analysis tool used was the regression of panel data using the software and views 10. From the research results the per capita expenditure and the number of poor were carried out. negative effects on the agricultural area, while the population, the number of industries and the level of education have a positive effect on the agricultural area. Only variable expenditure per capita and level of education has proven to be significant. The variable population, the poor population and the number of industries were insignificant. The descriptive analysis shows that the agricultural area in Central Java remains constant from year to year (constant).


BACKGROUND
The preferred treatment for severe methicillin-sensitive Staphylococcus aureus infections is flucloxacillin, a small-spectrum antibiotic administered intravenously (IV) and orally. However, clinicians switch to the less preferred broad-spectrum antibiotics because of the variable absorption after oral administration of flucloxacillin. A classical oral absorption test (OAT) requires overnight fasting and interruption of IV therapy, and is laborious. In the current study, we investigated whether a simplified OAT can be utilized in a clinical setting to guide antibiotic treatment in patients with severe S. aureus infections. For this, OAT IV therapy is continued and oral dosing is performed after a one-hour fast and implemented after a small study.

METHODS
In 196 patients receiving IV flucloxacillin by continuous infusion, a classical OAT (test A) or simplified version of the OAT (test B) was performed. In both tests, 1 g oral flucloxacillin was given and serum samples were taken prior to intake and at one and two hours after administration. Flucloxacillin concentrations were determined by high-performance liquid chromatography. Adequate absorption was defined as an increase of flucloxacillin concentration of at least 10 mg/l after one or two hours compared to baseline.

RESULTS
In a sample of 196 patients (85 F/111 M), test A was performed in 28 patients, and test B in 168 patients. Age, gender, and baseline values of creatinine and albumin were similar in both groups. The maximal increase of flucloxacillin absorption was highly variable between patients. In 26 (13%) of the 196 patients, the flucloxacillin increase did not reach the value of 10 mg/l. The median (interquartile range, IQR) maximal increase of flucloxacillin absorption was 22.0 (15-31.25) mg/l for test A and 21.5 (13-32.25) mg/l for test B. There was no significant difference in maximal increase of flucloxacillin absorption between test A and B (p = 0.74), nor between males and females (p = 0.95). Age, creatinine, and albumin were not correlated with flucloxacillin levels.

CONCLUSIONS
The simplified version of the OAT is useful to identify patients with adequate oral flucloxacillin absorption, and to ensure the effective continuation of an oral small-spectrum treatment.


between planner conservatism and the risk of infeasibility. This paper presents a novel real-time planning algorithm, chance constrained rapidly-exploring random trees (CC-RRT), which uses chance constraints to guarantee probabilistic feasibility for linear systems subject to process noise and/or uncertain, possibly dynamic obstacles. By using RRT, the algorithm enjoys the computational benets of sampling-based algorithms, such as trajectory-wise constraint checking and incorporation of heuristics, while explicitly incorporating uncertainty within the formulation. Under the assumption of Gaussian noise, probabilistic feasibility at each time step can be established through simple simulation of the state conditional mean and the evaluation of linear constraints. Alternatively, a small amount of additional computation can be used to explicitly compute a less conservative probability bound at each time step. Simulation results show that this algorithm can be used for ecient identication and execution of probabilistically safe paths in real time.


This position paper advocates the computerization of experiential activities and the utilization of these activities in teaching business subjects and conducting related research. In addition, it identifies some of the problems encountered in developing computerized experientials and using them in the classroom. Several propositions related to the use and development of computerized experientials are presented.


This article demonstrates how British evangelicals, German pietists, and Hungarian Protestants sought to 'educate' the masses outside the educational framework of ecclesiastical and state structure...


This thesis treats topics within the area of object recognition. A real-time view matching method has been developed to compute the transformation between two different images of the same scene. Th ...


Type 2 diabetes is a common and increasing health problem. The prevalence of diabetes in England is anticipated to reach 5.9% by 2020 (Yorkshire & Humber Public Health Observatory, 2008). People with diabetes are up to twice as likely to develop depression as those without the condition (Ali, Stone, Peters, Davies, & Khunti, 2006; Anderson, Freedland, Clouse, & Lustman, 2001). Approximately 10% meet the criteria for comorbid major depression (Ali et al., 2006; Anderson et al., 2001) yet only half of people with diabetes and major depression are recognised as depressed (Katon et al., 2004). Cross-sectional studies have found a prevalence of 5-15% for subthreshold depression (elevated depressive symptoms that do not meet DSM-5 criteria for major depression) in the general population (primary care) (Kessler, Zhao, Blazer, & Swartz, 1997; Rucci, Gherardi, & Tansella, 2003). In people with diabetes the prevalence of subthreshold depression is estimated at 17-20% (Ali et al., 2006; Anderson et al., 2001). In a Dutch study of patients with diabetes and moderate to severe anxiety or depression, only 20-30% of them were recorded as having any emotional problems by their diabetes nurses (Pouwer, Beekamn, & Snoek, 2006).Many factors contribute to under-recognition of depressive symptoms, with detection further complicated in patients with comorbid physical health problems (Prince, Patel, Saxena, Maj, Maselko, Phillips, & Rahman, 2007). Social and self-stigma are prevalent (Sherwood, Salkovskis, & Rimes, 2007) and are associated with reluctance to seek professional help (Barney, Griffiths, Jorm, & Christensen, 2006; Corrigan & Watson, 2002). Lustman and Clouse (2004) suggest that depression can also be regarded as an inevitable consequence of chronic illness by both patient and practitioner, and this might become a basis for not requesting or providing treatment (Lustman & Clouse, 2004).Addressing this under-recognition, and promoting help-seeking behaviour before depressive illness develops, requires a multifaceted approach. Two approaches identified as potentially beneficial are (a) mass media campaigns that stress that it is possible to prevent the onset of depressive disorders and (b) utilising the Internet as a stigma-reducing platform for depression, enabling targeting of tailored interventions for subgroups such as those with specific medical conditions (Cuijpers, van Straten, Warmerdam, & van Rooy, 2010). Online psychological support can be cost-effective and time-efficient (Christensen, Griffiths, & Jorm, 2004; Spek, Cujipers, NyklAycek, Riper, Keyzer, & Pop, 2010). Helping patients with subthreshold depression to better understand depression and recognise its early signs might also assist in long-term reduction in unmet need for treatment (Wells, Sherbourne, & Duan, 2005).The purpose of the present study, which was conducted as part of my PhD research, was to develop an Internet platform for people with Type 2 diabetes to promote psychological wellbeing. To facilitate the design of a platform that would engage patients and promote emotional literacy, I undertook a qualitative interview study to tap into their lived experience (Husserl, 1970). The aim of this qualitative study was to investigate the psychological symptoms experienced by adults with Type 2 diabetes, with special attention to the relationships patients made between physiological changes and psychological distress and the vocabulary used by patients to describe their distress.MethodsInterpretative Phenomenological Analysis (IPA)Interpretative Phenomenological Analysis (IPA) is an experiential qualitative approach with a strong idiographic focus. Its theoretical roots lie in European phenomenological philosophy and hermeneutics. Its ontological foundation directs attention to the world as it is lived, represented by the phenomenological phrase "Lifeworld." The analytical principles of IPA as a distinct research methodology were first developed by Jonathan Smith (Smith, 1996a). …


The IPO is a procedure by which a public company under common law is introduced on the stock exchange market using the shares issue, either by opening its existing capital to new stockholders or by proceeding by an equity increasing.
This procedure, while respecting certain conditions, opens the right to benefits and exemptions in terms of corporate tax for listed company, which will be seen later, and in terms of personal income tax for the individual investors in the company issued securities that concerns the business equity savings plans management.


Examines links between Chesterton and Tolkien "developing from a mutually strong religious conviction as regards their Catholicism, especially in its medieval historical experience." Sees a number of parallels between Chesterton's poem "The Ballad of the White Horse" and the values and events of Tolkien's major work.


THIS LIST OF REFERENCES, with a few exceptions, is a selection from materials on higher education that have come to the attention of the compilers between July I, 1950, and June 30, 1951. Institutional histories, annual reports, yearbooks, and proceedings of associations regularly devoted to the problems of colleges and universities have not been included. The compilers have intended that their selection should be comprehensive both in the subject matter of the references and in the methods employed in the treatment of the subject matter. They have tried to select from the large amount of published material those items that they believe will be most helpful to informed practitioners in the field of higher education. It has not been possible, of course, to include all titles that might be worthy of attention.


There is the need to divide Mongolia's lake research into trends of development stages and to provide a detailed analysis of modern lake research. The aim of this study is to identify the development stages of lake research in Mongolia and to analyse lake research development. This study provides a comparative analysis of the development trends of lake research carried out in the country. The historical development of lake research in Mongolia was divided into 4 stages in chronological order, highlighting the current research direction, scope, and contribution to geography. Since 1990, researchers from many countries have been able to conduct extensive research in Mongolia, and especially since the 2000s, lake research intensified owing to global warming and environmental change. Studies, in particular, focus on paleogeography, paleoclimate changes, lake water regimes and water level fluctuation. Mongolian lake-based studies have tended to identify environmental evolution from the Pleistocene to the Holocene. The investigated areas were primarily Khuvsgul Lake and Darkhad Basin, Lakes Valley and Gobi Lakes, the Great Lake Depression, Mongolian Altai and Khangai Mountain lakes. Since 1990, scientists from Russia, Mongolia, Germany, China, Japan, USA and South Korea have been increasingly focusing on research into lakes in Mongolia. Paleogeographic and paleoclimatic reconstruction, based on the lakes of Central Asia, is being conducted in an innovative manner. Dividing Mongolia's lake research into development stages and identifying research trends will help determine which areas of research can be developed in the future.


Mobile geospatial information service (MGIS) system emerged recently makes the applications of geographic information system into a new era. According to the analysis on J2EE, DCOM and CORBA, J2EE is more suitable for building MGIS system based on wireless application protocol (WAP). Using J2EE technology, this paper proposes an open, crossplatform, extensible, and "thin client" architecture for WAPbased MXGIS system, in which the presentation logic and business logic are isolated. Based on the architecture, an MXGIS application system was developed, which can work on WAP phone and uses a Java Servlet engine and a raster mapping technology to extend the capability of dynamically displaying maps for WAP microbrowser. The running results of the application system show that the architecture and used technologies are feasible.


It continues to be one of the major public health problems in large parts of the world, with an estimated 50 million dengue infections occurring annually. Dengue virus antigen has been found in a variety of tissues, predominately the liver and reticuloendothelial system. Viral replication is thought to occur primarily in the macrophages. Even though liver is not a major target organ, several pathological findings like hepatocellular necrosis, hyperplasia of Kupffer cells, inflammatory cell infiltration have been identified in liver biopsy specimens in patients with dengue fever.


Brazil is the largest passion fruit producer in the world. However, the yield is still considered low, and the cultivation of unsuitable varieties is one of the factors directly influencing this trait. As a consequence, breeding studies have been developed with the purpose of obtaining genetic materials with high yield, high fruit quality, and disease resistance. The objective of this study was to characterize and quantify the genetic variability in 18 genotypes of yellow passion fruit (Passiflora edulis Sims) with different levels of yield and disease resistance, using RAPD markers. The RAPD markers were obtained from 10 decamer primers and converted into a matrix of binary data. Estimations of the genetic dissimilarities between different genotypes and cluster analysis were performed. A total of 58 markers were generated, 63.80% of which were polymorphic. The genetic distances among genotypes varied from 0.040 to 0.354 and genotypes were subdivided into at least 5 groups of similarity. The dispersion graphs showed a low clustering tendency for yield and resistance to different diseases (septoriosis, anthracnose, scab, bacterial spot, and passion fruit woodiness disease). These results demonstrate a high genetic variability among the evaluated genotypes, which is valuable information when selecting promising materials to be used per se or as parents in genetic breeding programs.


TCR-mediated stimulation induces activation and proliferation of mature T cells. When accompanied by signals through the costimulatory receptor CD28, TCR signals also result in the recruitment of cholesterol- and glycosphingolipid-rich membrane microdomains (lipid rafts), which are known to contain several molecules important for T cell signaling. Interestingly, immature CD4 1 CD8 1 thymocytes respond to TCR/CD28 costimulation not by proliferating, but by dying. In this study, we report that, although CD4 1 CD8 1 thymocytes polarize their actin cytoskeleton, they fail to recruit lipid rafts to the site of TCR/CD28 costimulation. We show that coupling of lipid raft mobilization to cytoskeletal reorganization can be mediated by phosphoinositide 3-kinase, and discuss the relevance of these findings to the interpretation of TCR signals by immature vs mature T cells. The Journal of Immunology, 2000, 165: 5435–5442. Cell/bead conjugates can be distinguished by their FSC and SSC profile. Whereas T cells exhibited a high FSC and low SSC profile and hugged the x -axis, beads displayed a low FSC and high SSC profile and hugged the y -axis. In contrast, stable cell/bead conjugates appeared as a single event with both high FSC and high SSC intensities. Percentage of cell/bead con- jugates was calculated by dividing the percentage of cells falling into the cell/bead conjugate gate by the total percentage of live cells.


The paper summarises published and
unpublished data concerning the High Tatras to
date. Up to the present day, 258 species of spider
have been recorded from this region (Gajdos et al.
1999). Kronestedt (1999) mentioned the discovery
of another species of the Lycosidae family, Pardosa
fulvipes, from spruce stands near Stara Lesna. Until
now this species was known only from Scandinavia.
Up to now, 296 species have been documented
in the Western, High and Belianske Tatras.


This paper presents a computational method for the maximal robust controlled invariant set (MRCIS) of a class of uncertain switched systems, whose system matrices are unknown but are convex combinations of known matrices. A recursive algorithm is given to compute the MRCIS. It is also shown that the MRCIS can be obtained from the MRCIS of all subsystems.


Larvae of the sawfly genus Gilpinia Benson, a Palaearctic genus, attack conifers. Smith (1974) listed 24 species, two of which, G. frutetorum (Fabricius) and G. hercyniae (Hartig), were accidentally introduced into North America. Keys to known species of Gilpinia have been published for adults (Enslin 1917; Takeuchi 1940; Gussakovskij 1947; Berland 1947; Benson 1951; Okutani 1958) and for most European larvae (Lorenz and Kraus 1957; Běnes and Kristek 1979).


Introduction Adolescence is a transitional period which is characterized by many processes. Socially, it is a transitional period from dependent childhood to self-sufficient adulthood. Psychologically, it is a marginal situation when adjustment has to be made, namely those that distinguish childhood behaviours from adulthood. Adolescence spans from approximately 12 years to the early 20s with individual and cultural variations. For most people, adolescence is an intermediate state between being a child and being an adult. The state is a conflicting one since the adolescent feels like breaking childhood ties by becoming independent and autonomous. In the course of freeing themselves from emotional dependency, they go through a period that they reject parents and teachers' ways of doing things which result in conflicts. According to Bootzin, Bower, Crooker and Hall (1991), adolescence is a period of profound change in every aspect of life, during which both boys and girls experience a lot of bodily changes. An example is the development of primary sex characteristics which include complex changes in the genital, uterus, fallopian tubes and ovaries for the girls. The most obvious signs for boys' primary sex characteristics include the development of the penis, scrotum and testis. For many adolescents, menstruation, and nocturnal emission involves a certain degree of embarrassment and inconvenience. For that matter, adequate information about these changes needs to be made clear for them to accept the bodily changes. Those changes affect the way adolescents think about things and relationship with their families and their peers, which often produce stress. Adolescents frequently find themselves facing problems about alcohol, breaking parental rules and having sex. Peer attachment also caused emotional problems. Cogen, Birgra and Hans (1993) assert that sex plays an important role in adolescents' feelings, fantasies and social relationships. At this stage, adolescents are influenced by experimentation of sexual activities that is why the issue of sexually transmitted diseases, HIV/AIDS and teenage pregnancy are on the ascendancy. According to Cogen et al (1993), one factor contributing to the high rate of teenage pregnancies and births are the relatively low level of contraceptive use. Less than half of all adolescents regularly use some form of contraceptive. In Ghana, for example, the 20 th June, 1991 edition of the "Daily Graphic" showed that as many as 20 – 30% of all pregnancies between 1985 and 1990 were adolescents (Oppong, 1991). Several of these young people are at risk or already struggling with the costs of unwanted pregnancy or sexually transmitted diseases and HIV/AIDS. Flora, Maibach and Maccoby (1980) assert that most teenagers believe that contraceptives can guard against unwanted pregnancies; yet the sexually active ones do not use contraceptives. According to Hofferth and Hayes (1987), many adolescents do not use contraceptives the first time they have sex and many particularly younger adolescents delay for a year or more after first intercourse before using contraceptives. In the view of Hofferth and Hayes (1987), adolescents do not use contraceptives for varying reasons. Contraceptives are expensive and unavailable when needed. They are messy and reduce pleasure or increase levels of anxiety because of inexperience in their uses. Other factors that may contribute to a lack of contraceptive use include accessibility, knowledge as well as difficulty in using them. Hofferth (1987), as cited in Santrock (1987), purports that another factor that may contribute to lack of contraceptive use include adolescents' developmental issues such as reluctance to acknowledge ones' sexual activity, a sense of invincibility (belief that they are immune from the problems or issues surrounding sexual intercourse or pregnancy) and misconceptions regarding the use of appropriate contraception.


The growth of telecommunication sector has been increasing worldwide over the past few years. India also is not an exemption to this phenomenon with increased growth rate, employment generation and profitability. As a result, management of business also became more complex and challenging. Employees of these organizations play a pivotal role in sustaining this growth rate. The importance and necessity of employees has been emphasized by many researchers working in the field of management. This research is investigative in nature and evaluates the motivational level of employees of public and private sector organizations in the telecommunication industry. The motivational level is measured based on the perception of the sample population which is collected through questionnaire survey. The revised version of the Job Diagnostic Survey questionnaire is used for data collection for this research study. This paper also evaluates whether there are any changes in the motivational level of employees based on their gender, age, marital status, number of children and total work experience.


After twenty years of occupation, life in the occupied territories consisted of a familiar, but almost intolerable, routine for most of the Palestinians there. By the beginning of 1987, it was clear that no outside factors would help extricate the people from their harsh situation. The Palestinian issue was the last on the list of priorities at Arab summits. Palestinians could not fail to notice that, even when these leaders treated Palestine as a priority, they had very little to offer in the way of solutions or deliverance to the people living either under occupation or in the refugee camps. The PLO political strategy, conducted from Tunis and based on the construction of a Cairo–Amman diplomatic safety net for Arafat, produced no solutions, either to the occupation or the refugee problem. The PLO appeared resigned to the loss of its homeland and to the Palestinians' failure to achieve self-determination. The Israeli political situation remained mired in inflexibility and intransigence, as it had been since 1967. The only vibrant political arena was that of local politics in the occupied territories. It had a young national leadership, consisting of professionals and middle-class urbanites, each affiliated loosely to one of the many PLO groups in Tunis. But this leadership also lacked any clear strategy for ending the occupation, a frustrating failing that was accentuated in the 1980s by the liberation of oppressed people in East Asia, Eastern Europe and South Africa.


This Project is to handle actual questions of management of the computer networks security. Main focus of this project is to elaborate system conception of safety small computer networks and small wireless networks and realization with the help of software firewall Kerio Control in Windows area.


Hypogonadism is a clinical condition depicted by low androgen levels and associated with low muscle mass and strength, decreased ratio of lean body mass to adipose tissue, osteoporosis, decreased libido, decreased hematocrit, impaired cognition, and mood disorders [1]. It has been well established that aging is associated with decreased testosterone levels in males, and by 80 years of age, 40% of men have serum testosterone levels within the hypogonadal range [2]. Hypogonadism in aging males is often called andropause or androgen deficiency of the aging male (ADAM) [3]. However, assessment of andropause in aging males is difficult due to several factors, such as varying methods of testosterone measurements (total testosterone, bioactive testosterone not bound to sex hormone-binding globulin (SHBG), and free testosterone not bound to SHBG or albumin proteins) [4]. Further complicating diagnoses is that SHBG levels increase during aging, resulting in decreased bioactive and free testosterone levels [4]. Since andropause can affect the quality of life for aging men and the elderly population is predicted to double by 2025, investigation of andropause becomes imperative [5].


With the progress in the understanding of immunological mechanisms and susceptibility genes of psoriasis,an increasing number of targeted biological agents have been developed over the past decade.According to the mechanism of action,these agents are mainly divided into two groups,including costimulatory signal-blocking agents and inflammatory mediator-inhibiting agents.Inflammatory mediators targeted by these agents mainly include tumor necrosis factor α,interleukin-12 and interleukin-23.This review introduces the mechanism,clinical efficacy and safety of many biological agents which have been approved or unapproved but have shown vast potential for treating psoriasis in Europe and America.

Key words:
Psoriasis ;  Biologics ;  Immunity ;


Since listed in May 2001,edaravone,as a novel free radical scavenger,was widely used in the treatment of acute cerebral infarction.With the expansion of the clinical application scope,its serious adverse reactions were gradually revealed. In order to provide a reference for rational use of edaravone combined with the patients ' basic disease before treatment,this article reviewed literature about benefits and risks of edaravone in clinical application and then evaluated.


Between June and August 1990, field workers collected data on 1600 sterilization clients living in 16 rural small administrative units (thana) and 4 urban thana in Dhaka, Chittagong, Khulna, and Rajshahi, Bangladesh, to determine whether dissatisfaction among already sterilized couples accounted for the fall in sterilizations. 89.7% of vasectomy clients and 95.2% of tubectomy clients were satisfied. Just 4.4% of men and 2.4% of women expressed regret, about 95% of all clients believed they made the correct decision and more than 91% would have recommended it to others. Sterilization did not affect their sexual ability or the marital relationship. Men who had ever used contraceptives in the past were more likely to be satisfied than those who had never used them (93% vs. 3.9%; p .001). Yet most men who had never used contraceptives in the past were neither satisfied nor regretted their decision (92.2%). On the other hand, both groups of women (ever used and never used contraceptives) were satisfied (94.1% and 96.4%, respectively). The leading reasons for satisfaction for both men and women were that they would have no more children (64.1% and 65.9%, respectively) and that they would not need to worry about pregnancy (27.8% and 30%, respectively). The main reasons for regret for sterilization clients were frequent illness (43.8% for men and 12.5% for women) and deterioration of health (21.3% for men and 50% for women). Proper reception at the clinic effected satisfaction among clients, especially women clients (p .05). Essentially all clients knew they could not have any children after sterilization. Around 85% of men and 94% of women provided informed consent for the operation. No client of the voluntary surgical contraception program claimed coercion. These findings indicated that dissatisfaction was not responsible for the decline in sterilizations. The decline was probably due to the increased emphasis on and acceptance of oral contraceptives and condoms.


This paper reviews methods available to analyse movement and in particular migration. Stochastic process models seem able to provide a framework for microanalysis which can incorporate much of the complexity of such processes. However, a consideration of the effect of macro-constraints, in the form of limited opportunities for movement and of interhousehold competition, leads to a distinction between fixed transition rate and fixed state occupancy models. Alternative approaches to fixed state occupancy models are considered, and some of their potential strengths and weaknesses are discussed.


The Development and Implementation of H e a l t h Manpower P l a n n i n g i n Canada: W i t h S p e c i a l R e f e r e n c e t o B r i t i s h Columbia The purpose of t h i s study i s t h r e e f o l d : a) t o r e v i e w c u r r e n t h e a l t h manpower p l a n n i n g m e t h o d o l o g i e s b) t o d e s c r i b e i n c o n t e x t , the growth and changes i n m e d i c a l manpower p l a n n i n g i n Canada w i t h s p e c i a l r e f e r e n c e t o B r i t i s h C o l u m b i a . The manpower i s s u e s i n f i v e o t h e r h e a l t h p r o f e s s i o n a l a r e a s w i l l a l s o be e x p l o r e d . c) t o c r i t i q u e the Canadian and B r i t i s h Columbian manpower p l a n n i n g p r o c e s s e s u s i n g c u r r e n t models and recommend on changes t o the system which would i n c r e a s e e f f e c t i v e n e s s . The Canadian h e a l t h c a r e system s e t s the st a g e f o r a study of the development of h e a l t h manpower s t r u c t u r e s and e f f o r t s i n Canada. The r o l e o f t h e t h i r d p a r t y payment system i s i n v e s t i g a t e d as the p r i m a r y r e a s o n f o r government's i n c r e a s e d i n t e r e s t i n t h e c o n t r o l of p h y s i c i a n manpower and h e a l t h c a r e l a b o u r c o s t s i n g e n e r a l . Problems i n d e f i n i n g h e a l t h and j u r i s d i c t i o n a l o v e r l a p s a r e o u t l i n e d . P l a n n i n g models and t h e i r r e l a t i o n t o h e a l t h manpower p l a n n i n g a r e d e s c r i b e d . Government's i n t e r e s t t o r e p l a c e the e n t r e p r e n e u r i a l p l a n n i n g methods w h i c h preceded h e a l t h i n s u r a n c e w i t h r a t i o n a l p l a n n i n g methods i s d i s c u s s e d . The major r a t i o n a l p l a n n i n g methods and t h e i r l i m i t a t i o n s a re r e v i e w e d . These i n c l u d e p h y s i c i a n ^ p o p u l a t i o n r a t i o s , manpower needs, economic demand and s e r v i c e t a r g e t methods. Formal f e d e r a l and p r o v i n c i a l s t r u c t u r e s e s t a b l i s h e d t o a d d r e s s manpower i s s u e s a r e a n a l y z e d as are the b u f f e r and l o b b y groups e s t a b l i s h e d t o moderate t h e i r e f f o r t s . As p h y s i c i a n manpower p l a n n i n g i s t h e p a t t e r n s e t t e r f o r a l l o t h e r h e a l t h manpower p l a n n i n g , i s s u e s i n t h i s a r e a a r e examined i n c o n s i d e r a b l e d e t a i l . T h i s d i s c u s s i o n i s f o l l o w e d by a c o n s i d e r a t i o n o f p l a n n i n g i n f i v e o t h e r h e a l t h p r o f e s s i o n a l a r e a s : n u r s i n g , pharmacy, d e n t i s t r y , r e h a b i l i t a t i o n and d i e t e t i c s . T h i s d i s c u s s i o n shows how t h e s e groups have a l l c o n c erned t h e m s e l v e s w i t h t h e i r own i n d i v i d u a l s i t u a t i o n s and not w i t h i n t e r p r o f e s s i o n a l a r e a s . I n d i v i d u a l p r o f e s s i o n a l p r i o r i t i e s a r e a l s o d i s c u s s e d .


Purpose: To study short-term outcomes of thermochemoradiotherapy (TCRT) followed by radical surgery in patients with non-small cell lung cancer (NSCLC). Materials and methods: The study included 38 patients with stage III lung cancer, who were treated at the Cancer Research Institute of the TNIMC (Tomsk, Russia). The study group patients (n=18) received combined modality treatment consisting of hyperfractionated radiation therapy (40 Gy total dose in twice-daily fractions of 1.3 Gy each) given concurrently with 2 cycles of chemotherapy with paclitaxel / carboplatin after 10 sessions of local hyperthermia followed by surgery. In the control group (n = 20), only surgical treatment was performed. Results: The overall tumor response to TCRT was 94.4%, including complete response (22.2%) and partial response (72.2%). All patients tolerated local hyperthermia well. All patients (100%) underwent radical surgery. There were 23 (60.5%) lobectomies, 13 (34.2%) pneumonectomies and 2 (5.3%) combined surgeries. Postoperative complications were observed in 22.2% of patients in the study group and in 20.0% of patients in the control group. The mortality rates were 0 and 5.0%, respectively (р>0.05). Conclusion: Preoperative TCRT in patients with stage III NSCLC resulted in a significant tumor regression, was well tolerated by the patients and did not have a negative impact on postoperative period and mortality.


Matching 2-D gel electrophoresis images is the first and a major step in bioinformatics study of protein. This paper presents an improved implementation of a thin-plate spline image registration. The effectiveness of the algorithm is demonstrated on matching 2-D gel protein separation profiles.


In magnetic observatories the Earth's magnetic field is continuously recorded and the acquired data are calibrated so that the evolution of the field can be studied on time scales ranging from seconds to decades. The French network (the so called BCMT) includes 18 observatories around the world and the different types of data produced are freely accessible on several data centres. We will describe a typical infrastructure of a magnetic observatory, the measurement techniques, the instruments used, the general processing applied to obtain calibrated data and finally the environmental constraints that have to be respected in order to acquire suitable data. If magnetic observatories were originally set to monitor the slow variations of the Earth's main magnetic field, they are more and more often used for space-weather monitoring and to study signal generated in the ionosphere and magnetosphere. This new range of applications implies an evolution of the network, of the acquisition and distribution techniques. The strategy we developed to respond to these new challenges will be also presented.


Background: Despite the impressive results obtained with imatinib, inadequate response or resistance are observed in certain patients. It is known that imatinib is a substrate of a multidrug resistance gene ( MDR1 ). Thus, interindividual genetic differences linked to single nucleotide polymorphisms in MDR1 may influence the metabolism of imatinib. The present study has aimed to examine the impact of MDR1 polymorphisms on the hematologic and cytogenetic responses in 70 chronic myeloid leukemia patients who received imatinib. Methods: We used a polymerase chain reaction followed by restriction fragment length polymorphism to identify different profiles of 1236C>T, 2677G>T and 3435C>T in MDR1 . Results: The distribution of the three SNPs in responders and poor responders did not show any particular trend (P>0.05). The T allele was slightly higher in responders, but not significantly regardless of the type of SNP (40.3% vs. 33.8% for 1236C>T; 25% vs. 14.7% for 2677G>T and 33.3% vs. 22% for 3435C>T). The dominant model showed a similar trend (P>0.05). Diplotypes composed by the T allele in different exons were frequent in responders. Haplotype analysis showed that 1236C-2677G-3435C was slightly higher in poor responders (60.02%) compared to responders (50.42%). However, 1236T-2677T-3435T was frequent in responders (16.98%) compared to poor responders (13.1%). Overall, none of the haplotypes were associated with IM response in our cohort (global haplotype association test, P=0.39). Conclusion: The identification of 1236C>T, 2677G>T and 3435C>T polymorphisms may not be advantageous to predict imatinib response for our chronic myeloid leukemia patients.


The last decade has seen a tremendous growth in the mutual fund industry. Today the Indian market is flooded with more than a thousand mutual fund schemes, promising better returns than others. Mutual Funds are essentially investment vehicles where people with comparable investment objective come together to pool their money and then invest accordingly. With the increase in domestic savings and development in employment of investment through markets, the need and scope for mutual fund operation has improved immensely. But about 75% people are still investing in Post office, MIS and bank deposit because of the lack of awareness in rural areas. For saving investors' money, it becomes necessary to evaluate the performance of mutual fund portfolio so that investors can make their investment decisions rationally. This evaluation would help in checking the main idea of "putting all eggs in different baskets" behind mutual funds and analyzing that the idea is good for investors or not. This study of Performance evaluation would help the investors to choose the best schemes available and will also help the AUM's in better portfolio construction and can rectify the problems of underperforming schemes. Hence in this paper an attempt has been made to evaluate the performance of index funds among SBI & UTI (public sector) and HDFC & ICICI (private sector) on the basis of monthly returns compared to benchmark returns over the period of 3 years and to appraise the performance of different category of funds using risk adjusted measures as suggested by Sharpe, Treynor and Jensen.


For the LHC Run 2 the ALICE HLT architecture was consolidated to comply with the upgraded ALICE detector readout technology. The software framework was optimized and extended to cope with the increased data load. Online calibration of the TPC using online tracking capabilities of the ALICE HLT was deployed. Offline calibration code was adapted to run both online and offline and the HLT framework was extended to support that. The performance of this schema is important for Run 3 related developments. An additional data transport approach was developed using the ZeroMQ library, forming at the same time a test bed for the new data flow model of the O2 system, where further development of this concept is ongoing. This messaging technology was used to implement the calibration feedback loop augmenting the existing, graph oriented HLT transport framework. Utilising the online reconstruction of many detectors, a new asynchronous monitoring scheme was developed to allow real-time monitoring of the physics performance of the ALICE detector, on top of the new messaging scheme for both internal and external communication. Spare computing resources comprising the production and development clusters are run as a tier-2 GRID site using an OpenStack-based setup. The development cluster is running continuously, the production cluster contributes resources opportunistically during periods of LHC inactivity.


115 pairs of RM primers were used in the SSR assay of nine samples, including one sorghum, four paddies and their four hybrids. The statistical result of the experiment revealed that there was a certain homology between paddy and sorghum. The hybrids mainly expressed paddy-like DNA bands, as well as some other bands. Which indicates that in the hybrids some DNA segments of sorghum are inserted into the genome of paddy. The results prove the availability of distant hybridization between rice and sorghum in the molecular level.


Few civilizations were as determined and capable to transform the countryside as the Romans. Regarding the ever more studied Southern Meseta in the Iberian Peninsula, the Roman administration established a hierarchy of around twenty civitates and their territoria . In this text we aim to study the origin of the territory of a town that has been subject to very limited research in historiography, Consabura . However, this territory shows the main features of Romanisation like very few others –through its Roman roads and footpaths, the use and management of water, the increase in the economic exploitation of the ager , the hierarchy of the settlements, etc.
All these aspects create Consabura 's identity, located in the present Consuegra (Toledo). The town controlled a vast and strategic territory between the Tagus valley and the Guadiana valley, the ager Consaburensis , which was born in the Protohistoric times, especially from the Second Iron Age, and could have dominated an area of 3,000 km2 during the Roman period.


In this paper, we present p-channel GaAs MOSFET having as gate insulator fabricated on a semi-insulating GaAs substrate, which can be operated in the depletion mode. thick undoped GaAs buffer layer, thick p-type GaAs epi-layer, undoped thick AlAs layer, and thick GaAs cap layer were subsequently grown by molecular beam epitaxy(MBE) on (100) oriented semi-insulating GaAs substrate and this wafer was oxidized. AlAs layer was fully oxidized as a thin film. The I-V, , breakdown charateristics of the fabricated GaAs MOSFET showed that wet thermal oxidation of AlAs/GaAs epilayer/S I GaAs was successful in realizing depletion mode p-channel GaAs MOSFET.