This article examines the research literature to determine whether the provision of quality early childhood education (ECE) lowers the risk of a child developing special education needs (SEN) and mediates the intensity of support for children with an identified exceptionality. Schools play a crucial role in reducing developmental gaps assessed at school entry, but their success comes with great expense in special education and related costs. Research indicates that ECE could narrow these gaps and better prepare children for success in school, and this realization is slowly being reflected in public policy. Based on our literature review, we describe the benefits of quality ECE in lowering special education expenses. Specific play-based learning pedagogical strategies support all children in optimizing academic progress, language development, social skills, and emotional-behavioural regulation. Professional learning for early childhood educators can build capacity to embed effective pedagogy into daily practice. The provision of quality ECE that makes a difference depends on the knowledge and skills of this workforce. Abstract This article examines the research literature to determine whether the provision of quality early childhood education (ECE) lowers the risk of a child developing special education needs (SEN) and mediates the intensity of support for children with an identified exceptionality. Schools play a crucial role in reducing developmental gaps assessed at school entry, but their success comes with great expense in special education and related costs. Research indicates that ECE could narrow these gaps and better prepare children for success in school, and this realization is slowly being reflected in public policy. Based on our literature review, we describe the benefits of quality ECE in lowering special education expenses. Specific play-based learning pedagogical strategies support all children in optimizing academic progress, language development, social skills, and emotional-behavioural regulation. Professional learning for early childhood educators can build capacity to embed effective pedagogy into daily practice. The provision of quality ECE that makes a difference depends on the knowledge and skills of this workforce. We undertook an extensive review of the established national and international literature, with particular attention to longitudinal studies. A focus was placed on longitudinal studies, allowing us to examine the long-term benefits of investing in children's lives at a young age, and to display the social, emotional, academic, and economic benefits that ECE has for the general population. Given the time span of longitudinal studies, some of which began in the 1960s and tracked children through early adulthood, much of this data can seem old though foundational to the field. Subsequently, our review paid particular attention to more recent data as presented by Alexander, Beckman, Macdonald, Renner, & Stewart (2017); Pelletier & Corter (2018); and Taggart, Sylva, Melhuish, Sammons, & Siraj (2015). Dominant themes that emerged across all of these studies were of particular interest to us.


This paper examines the influence of classroom teaching on student understanding of the piecewise function. The participants were two experienced mathematics teachers and their 9th grade students. Using a theoretical standpoint that emerged from an analysis of APOS theory, the paper illustrates that the teachers differ remarkably in their approaches to the essence of the piecewise function and this, in turn, affects greatly their students" understanding of this notion. Action-oriented teaching, which is distinguished by the communication of rules, procedures and factual knowledge, confines students" understanding to an action conception of piecewise function. Process-oriented teaching, which priorities the concept and illustrates it across the representations, promotes students" understanding towards a process conception of function.


The aim of this study is to assess values of leadership principles for developing governance in Minangkabau culture. It appears that the values in Minangkabau culture can be applied to develop principle of society in Indonesian perspective. The research method used qualitative method, especially using hermeneuticreflective approach in generating findings with five steps on descripting and analysing traditional proverbs. The research results showed that the principle system in Minangkabau proverbs is loaded with eleven values which can be use as principles for national leaders.


The development of school psychological service in the United States has evolved into a large and potent force. School psychologist plays one of the most significant roles in this service system and becomes increasingly important. However,the profession of school psychology in China is barely in its infancy,with obscure role and function of personnel workers,weak professional identity and structure,immature working approaches and models,etc. As the considerable demands in school settings increase,it becomes apparent that the absence of the school psychologist in Chinese education and mental fields is problematic. Given the fact that classroom teachers are still the service providers in school systems in China,the development of school psychology in China is warranted,particularly in the era of "inclusive education". They can make psychology great contribution to education,and promote the progress of Chinese education,both in theoretical and practical field.


A 24-year-old unmarried male presented with a rudimentary reduplicated penis. This case is reported for its rarity and exotic presentation.


Printed circuit heat exchanger (PCHE) is promising in the application of energy conversion system with its high compactness and efficiency. In this paper, the flow and heat transfer performance of supercritical carbon dioxide (SCO2) PCHE are numerically investigated with multiple channels and different channel lengths. The results show that the heat transfer performance of the Zigzag channel PCHE is increased more than 11% comparing to the wavy channel, while it brings more flow resistance. The pressure drop in the Zigzag cold and hot channels was about two and four times of the wavy channel, respectively. It is recommended for the wavy channel PCHE on account of its better overall performance factor than zigzag channel PCHE. Through the analyses of flow characters among multiple channels, it shows good homogeneity of flow distribution for the flow distribution coefficient in each channel close to 1.0, which is able to effectively avoid uneven flow distribution resulting in high local temperature of the heat exchanger. Furthermore, the overall performance of PCHEs with different core lengths are compared, presenting nearly 10% difference on the thermal efficiency.


Connective tissues contain collagen fibers bound together. A suitable scaffold for regenerating connective tissue should be able to help collagen synthesis. Electrospun nanofibers are highly used in tissue engineering applications as scaffolds. It has been determined that fibrous scaffolds with aligned structures are more suitable substrates for cell orientation, proliferation, and adhesion. In this study, we fabricated a novel electrospun scaffold. At first, we fabricated an electro spun layer from gelatin. Afterward, we put electro spun PLLA yarns on the layer's surface and then fabricated another electro spun gelatin layer on them to have an aligned fibrous structure (sheet+yarn). The morphological properties of the sheet+yarn were measured. We studied fibroblast's behavior in contact with the sheet+yarn using MTT and Sirius red assays. The morphological results showed that there was not a significant difference between the sheet+yarn and a simple electro spun gelatin layer that did not contain yarns (sheet). But, the results of in vitro assays showed that fibroblasts produced more collagen and proliferated better in contact with the sheet+yarn in comparison with the sheet. So, the sheet+yarn as a novel electro spun scaffold can be used for collagenous connective tissue regeneration.


The housing (1 '' '') of a cellular wheel sluice comprises serving for temperature control chambers (30b, 30c), in the tempering agent feed and -Abfuhr ports (38b, 38c, 39c) open. These chambers (30b, 30c) each enclose an inlet port (5) and an outlet pipe (6) of the lock.


This study aims to determine the implementation guidance to PPAT by
Yogyakarta City Land Office, to determine the implementation of the supervision
of PPAT by the Land Office in Yogyakarta and determine the role of professional
organizations in the guidance and supervision of PPAT when carrying out the
duties and position.
This research is a field that emphasizes the use of primary data obtained
through interviews with the respondents in order to determine the effectiveness
and efficiency of a rule / law / certain condition or review the unwritten legal
norms. How to collect data in this study is to examine secondary data followed by
a study of primary data in the field. Location of the research conducted at the
Land Office City of Yogyakarta, Yogyakarta Special Region. Samples / research
subjects in research is the Head of the Land Office KotaYogyakartam, Chairman
of the Land Deed Official Yogyakarta and Lecturer at Gadjah Mada University
Master of Notary, while the speaker is Lecturer in Land Law Faculty o f Law,
University of Gadjah Mada, while the analysis of data used in this study is
qualitative the descriptive method.
Based on the research results and the discussion that has been done it can
be concluded that the first, based on Government Regulation No. 37 Year 1998 on
the Regulation of Land Deed Official Position, the minister implement guidance
and supervision of the implementation of the tasks PPAT. Head of National Land
Agency Regulation No. 1 of 2006 determines that the guidance and supervision of
the implementation of the tasks performed by the Head of the PPAT, Head of
Regional Office and the Head of the Land Office. Second, implementation of
surveillance of PPAT by the Land Office of Yogyakarta city is to implement
direct examination at the time of the inauguration of spaciousness and PPAT,
while the form of supervision is done by checking the reports associated with the
deed executed and make Reportorium books / book list PPAT deed. Third,
Implementation guidance to PPAT by the Land Office in Yo gyakarta is helping
deliver and explain the policy and regulations on land as well as the technical
implementation of the task instructions PPAT. Fourth, the role of professional
organizations to develop and supervise the PPAT in carrying out his duties is the
responsibility of professional organizations forms PPAT morally with regard to
ethics or behavior PPAT itself, both inside and outside the office.


The standard free energy of hydrophobic interaction between alkyl chains has been measured in aqueous solutions of t-butanol, dioxan, dimethyl sulphoxide and dimethyl formamide.The results make it clear that hydrophobic interaction (in the sense of a pair-wise interaction between hydrophobic groups otherwise surrounded by water) is not simply a partial reversal of solution of the non-polar molecules in water. Hydrophobic interaction should therefore be distinguished from phenomena, such as the formation of detergent micelles or phospholipid bilayers, in which non-polar molecules are completely removed from water. Only in the latter case is "reversal of solution" a correct description.The experimental method was measurement of conductance of long chain alkyltrimethylammonium carboxylate solutions. Ion pair association constants, and hence free energies of ion pair formation were calculated from these data. Then by systematically varying the alkyl chain length it was possible to separate the free energy of hydrophobic interaction from the electrostatic interaction between the charged groups.Moderate concentrations of t-butanol, dimethyl sulphoxide and dimethyl formamide strengthened hydrophobic interactions. All concentrations of dioxan weakened hydrophobic interactions. Maximum hydrophobic interaction occurred with those solute concentrations which maximised the three dimensional hydrogen bonded structure of water.The results explain some of the odd effects of alcohols and other structure making solutes on the stability of proteins.


ABSTRACT With the continuous improvement of people's material living standards, public health and national fitness has become a social topic, and has been widely concerned by the public, in terms of the traditional physical education and impact of the concept of health. This not only needs the school to carry on the multi-directional adjustment to the physical education teaching, but also needs the physical education teacher to respond positively to this in order to adapt to the development needs of the times and society. This study uses the analytic hierarchy process (AHP) to construct the professionalization model of physical education teachers in Colleges and Universities, and makes decision on the index weight of the model through fuzzy comprehensive evaluation. The results show that the weight of the first-class indicators of P.E. Teachers' professionalization model from large to small is ability > quality > knowledge, and the consistency ratio (CR) of the model indicators is less than 0.1, and the fuzzy score of the model is 85 points. Therefore, the model of P.E. Teachers' professionalization constructed in this study has consistent indicators and shows good applicability. This does not only provide the basis for the professional development evaluation of College PE teachers, but also provides research ideas for the development of the sports industry from the perspective of public health.


In recent era of digitalization, all fields of science are engaged in using sophisticated technology to deliver fast and straightforward work. In the completion of construction projects we often encounter complex problems. In general, the factors that affect employee productivity are (a) Low motivation levels of employees due to differences in two cultures (b) unresolved conflicts (c) The low level of entrepreneurial spirit of employees in exploiting the opportunities that exist (d) The failure of the company in regulating Human Resources (HR), (e) The absence of leadership characters between two employee cultures (d) The failure of the company to utilize advanced technology currently related to settlement effective and efficient work. Weaknesses in considering labor productivity are caused by productivity problems in very complex projects and the presence of internal and external factors that influence them. In this case, one construction project has two different ethnicities and cultures, namely Minang culture and Sundanese culture, based on field observations. There are several solutions to overcome them, namely (1) Employee Entrepreneurship Productivity, (2) Work Motivation, (3) Leadership, (4) Human Resources and (5) Work Information Technology. The method used is the MANOVA Statistics (Multivariate of Variant analysis) and realized in SEM (Structural equations Modeling). The results obtained are a model that is effective in increasing employee productivity in the construction industry.


The article points out the challenges and prob le ms of continued use in water resources,sets forth the management of future wa ter resources clearly and calls people to economize or water to protect continue d use in water resources.


Japan is one of the few countries in the world to ban low-dose oral contraceptives; this position is gaining support from environmental groups who fear that the hormones contained in the pill will affect the reproductive health of the women who take them and of animals who come in contact with wastes containing estrogen. The Women's Network for Ecology wants the government to investigate the effects of the pill on the newborn of women who took the pill while pregnant. A Network member states that 30 years of use by other countries does not ensure the pill's safety. The Stop] Dioxin Pollution Kanto Network claims the hormones excreted by women who take the pill pollute waters and harmfully affect wild animals. The Director of the Family Clinic of the Japan Family Planning Association counters these claims by noting that women's urine is filled with hormones; a woman in the 40th week of pregnancy has 10,000 times more hormones than a woman who takes the pill. A professor at Ochanomizu University says the ban is one-sided and ignores women's opinions. The Ministry of Health and Welfare and the Central Pharmaceutical Affairs Council have been considering legalization of the pill since the beginning of the decade; the ban was supposed to have been lifted last year. According to an article in the Economist, Japanese women's groups believe the ban is for economic reasons; its reversal would cause women to turn from abortions which currently bring in an estimated Y100 billion annually, a figure that is denied officially. The article also mentions a study by the Asia-Pacific Research Centre which indicates that abortions are underreported by at least threefold in Japan; this means that 50% of all pregnancies in Japan are aborted.


Simultaneous absorption and scattering mappings are used to study the influence of local defects on the laser damage threshold of thin films. The same area is mapped for absorption an d scatter before and after irradiation at the threshold fluence. The study is performed for an uncoated fused silica substrate and two single-layer films deposited on fused silica substrates at a wavelength of (lambda) equals 1.06 micrometers . Initial results seem to indicate that the irradiation can create and enhance absorption and scattering defects.


The aim of this research is to analyze the effect of operating costs on operating income (BOPO), total asset turn over (TATO), and return on assets (ROA), on share prices of Islamic companies in 2018-2022. This study uses a quantitative approach using secondary data as the type of data. The data analysis technique used in this study is using multiple linear regression analysis techniques, where the Effect of Operating Costs on Operating Income (BOPO), Total Asset Turn Over (TATO), and Return On Assets (ROA) as independent variables and stock prices as variables dependent with data processing analysis tools using SPSS 24.0. Based on the results of the research analysis, the findings in this study indicate that partially the effect of operating costs on operating income (BOPO) has a significant effect on stock prices. The results of the next study partially Total Asset Turn Over (TATO) have a significant effect on stock prices. Return On Assets (ROA) has a significant and significant effect on stock prices. Simultaneously the Effect of Operating Costs on Operating Income (BOPO), Total Asset Turn Over (TATO), and Return On Assets (ROA) have a significant effect on Prices Keyword


AIM: To construct the eukaryotic expression vector that specifically drives FCY1/TK double suicide gene by prostate-specific membrane antigen promoter(PSMAP)and to investigate the toxic effects of single or double gene on transfected prostate cancer cell line LNCaP after prodrug treatment.METHODS: Genomic DNA was extracted from benign prostate tissues and prostate-specific membrane antigen promoter(PSMAP) fragment was obtained by polymerase chain reaction (PCR).The pCMV promoter on eukaryotic expression vector pIRES was replaced by PSMA promoter and PSMAP-IRES vector was obtained. The recombinant plasimd PSMAP-IRES was identified by restriction analysis and DNA sequence. Then the gene FCY1 and TK was cloned into corresponding sites of PSMA-IRES and the pPSMA-IRES-FCY1-TK eukaryotic expression vector was obtained.Lipofection- mediated genetransfers were performed with the obtained vector and a control plasmid, pIRES, in human prostate cancer cell line LNCaP cells.RT-PCR was used to demonstrate successful transcription.The toxic effects of 5-FC, GCV, and both of them on transfected LNCaP cells were explored by MTT assay. RESULTS : A 1400 bp DNA fragment was amplified with PCR.Sequence and restriction analysis showed that PSMA promoter by amplified was identical with that of GenBank reported(GenBank accession number AF007544). The expression of suicide genes TK and FCY1 could be detected by RT-PCR.The growth inhabition rate (GIR) in double gene group were higher than that of single gene.(P0.05) CONCLUSION : pPSMA-IRES-FCY1-TK double suicide gene system has significant toxic effect on LNCaP cells in vitro, which was superior.


Crop depredations by staging cranes have been an annual problem at Daursky State Biosphere Reserve in southern Siberia. In September 2001 we met at Daursky when crane populations peaked to investigate the problem and suggest methods to reduce damages. Peak of crane staging coincided with grain harvest. We counted ≈ 30,000 cranes of 5 species, primarily demoiselles (Anthropoides virgo), in the area. Poor grain yields and cooperative farming systems discouraged efforts to reduce damage. Moving crops further from roost areas may be the most reasonable short term control method, but it's effectiveness is yet untested. Hazing, lure crops and alternate food plants also may work. PROCEEDINGS NORTH AMERICAN CRANE WORKSHOP 9:145-149


Background: The current standard of care for locally advanced esophageal adenocarcinoma (EAC) involves neo-adjuvant chemoradiation therapy (neo-CRT) followed by surgery. However, response to neo-CRT is poor and resistance remains a significant barrier to effective treatment. There are currently no clinical biomarkers to predict treatment response in EAC. Evidence supports a role for microRNA-34a (miR-34a) as a tumor suppressor in cancer, however, the role of miR-34a in the tumor response to therapy in EAC is largely unknown.
 Methods: Irradiation of EAC cell lines was performed using an Xstrahl RS225 X-ray irradiator at a clinically-relevant dose of 2 Gy. Radiosensitivity of EAC cell lines (OE33 P, OE33 R, OE33, OE19, Flo-1Par and Flo-1LM) was assessed by the gold standard clonogenic assay. miR-34a expression was assessed by qPCR. EAC tumor biopsies were obtained from consenting patients undergoing diagnostic endoscopy. Pathological response of the resected tumor was assigned by a pathologist using the Mandard Tumor Regression scale. miRTarBase and KEGG pathway analysis were used to identify predicted target genes and pathways of miR-34a.
 Results: miR-34a was demonstrated to be expressed in a panel of EAC cell lines (OE33 P, OE33 R, OE19, Flo-1Par and Flo-1LM cells). Interestingly, miR-34a expression was significantly decreased in EAC cell line models of both acquired radioresistance (OE33 R) and inherent radioresistance (OE19). miR-34a was also significantly decreased in a model of radioresistant metastatic EAC (Flo-1LM). Supporting in vitro data, in pre-treatment tumor biopsies from EAC patients (n=18), miR-34a was significantly decreased in patients having a subsequent poor pathological response to neo-CRT, when compared to patients having a good pathological response to neo-CRT. Target and pathway analysis demonstrated miR-34a-mediated regulation of genes and pathways associated with treatment resistance, including the complement system, cellular metabolism and p53 signaling, among others.
 Conclusion: Decreased miR-34a expression is associated with radioresistance across a panel of in vitro EAC models and in pre-treatment tumor biopsies from EAC patients having a poor pathological response to neo-CRT. This highlights a potential role for miR-34a as a novel biomarker predicting response to neo-CRT in EAC. Analysis of validated and predicted gene targets of miR-34a identified a number of pathways associated with treatment resistance. We are currently investigating the functional role of miR-34a in modulating tumor response to radiation in vitro to determine its potential as a novel therapeutic target to boost treatment response in EAC.
 Citation Format: Christina Cahill, Stephen G. Maher, Rebecca O'Brien, Wei-Lin Winnie Wang, John V. Reynolds, Jacintha O'Sullivan, Niamh Lynam-Lennon. Investigating the role of miRNA-34a in the resistance of esophageal adenocarcinoma to neoadjuvant chemoradiation therapy. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 3806.


This paper proposes a method for calculating the detection and recognition range of low-level television systems in the active-pulse and passive operating regimes. The method uses the contrast-frequency characteristic of the system - the dependence of the minimum contrast of a resolvable target on its angular frequency - and is conceptually similar to the corresponding methods accepted in thermal vision.


The neutral $Z$ boson pair production due to radion resonance at the Large Hadron Collider (LHC) is an interesting process to explore the notion of warped geometry (Randall-Sundrum model). Because of the enhanced coupling of radion with a pair of gluons due to trace anomaly and top(quark) loop, the radion can provide a larger event rate possibility as compared to any new physics effect. Using the proper radion-top-antitop (with the quarks being off-shell) coupling, we obtain the correct radion production rate at LHC and explore several features of a heavier radion decaying into a pair of real $Z$ bosons which subsequently decays into charged $4l\text{ }(l=e,\ensuremath{\mu})$ leptons (the gold-plated mode). Using the signal and the background event rate, we obtain bounds on radion mass ${m}_{\ensuremath{\phi}}$ and radion vacuum expectation value $⟨\ensuremath{\phi}⟩$ at the $5\ensuremath{\sigma}$, $10\ensuremath{\sigma}$ discovery level.


The situation of living electricity consumption and real estate development in Hangzhou was investigated, and energy efficiency of buildings was carried out. Application situation of building energy efficiency technologies was summarized. That gives some references to the continued study.


Aiming at solving problems in theoretical teaching on the analog electronic technology.It is further expounding the application of the EDA simulation software-Multisim7 in teaching the analog electronic technology by providing specific teaching examples.The EDA simulation software-Multisim7 may help to deal with complex problems in teaching the analog electronic technology,make demonstrating experiments applicable in practical teaching,as well as arouse students' interest,enforce students'mastering of concerned theoretical knowledge and in addition,develop students'abilities to find and solve problems by applying theoretical knowledge to practice in their study.


A prosthesis for insertion in an ear to reduce pain resulting from TMJ disorders. The ear insert has a predefined shape conforming to the shape of the ear canal when the jaw is in an open position. The ear insert supports the TMJ and associated secondary musculature to reduce strain in the TMJ area, including the muscles, ligaments, nerves, and the temporo-mandibular joint itself. The insert is hollow in the inside to permit hearing and is made of a rigid material which retains the shape of the ear canal. A scalloped indenture extends across a surface of the ear insert positioned behind the tragus.


Based on the test research and engineering practices on reinforcing the loose bed landslide with prestressed anchoring rope(anchor cable),the problems concerned with the stress response,anchoring force,exhaustion of prestress force and the group of anchoring ropes are explored.The practical engineering applications of reinforcing the landslide and the slope in rock fracture zone,slump mass and sandy gravel are also expounded in detail in this paper. (According to research and practice,the following mechanism on reinforcing loose bed landslide and slope are expounded.The regularity of transmission and response of stress is similar in loose bed and in rock bed.The anchoring force in anchoring section loose bed may be strong enough through expanding the aperture and grouting in twice times.Exhaustion of prestress force with compression creep of loose bed is limited and can be compensated.Effect of a group of anchoring rope is regular,as the interval of the rope is suitable. Under some conditions,the engineering of reinforcing landslide and slope in rock fracture zone,slump mass and sandy gravel is more cheap,high speed and safe with prestressed anchoring rope than anti slide pile.The Laoyayan landslide of the Baoji Chengdu railway is a example in which the reinforced loose bed was applied alone with prestressed anchoring rope.Using prestressed anchoring rope for reinforcing the excavation wall of sandy gravel in building of Bank of China is the first time in Chengdu city.The Badu landslide of Nanning Kunming railway in slump mass,a main reinforcing engineering in which the prestressed anchoring rope was applied,is a most big controlled landslide in railways.)


This article reports of a study on the production of charcoal briquettes from biomass for community use. Manufacture of charcoal briquettes was done using a briquette machine with a screw compressor. The aim of this research was to investigate the effects of biomass type upon the properties and performance of charcoal briquettes. The biomass samples used in this work were sugarcane bagasse (SB), cassava rhizomes (CR) and water hyacinth (WH) harvested in Udon Thani, Thailand. The char from biomass samples was produced in a 200-liter biomass incinerator. The resulting charcoal briquettes were characterized by measuring their properties and performance including moisture content, volatile matter, fixed carbon and ash contents, elemental composition, heating value, density, compressive strength and extinguishing time. The results showed that the charcoal briquettes from CR had more favorable properties and performance than charcoal briquettes from either SB or WH. The lower heating values (LHV) of the charcoal briquettes from SB, CR and WH were 26.67, 26.84 and 16.76 MJ/kg, respectively. The compressive strengths of charcoal briquettes from SB, CR and WH were 54.74, 80.84 and 40.99 kg/cm2, respectively. The results of this research can contribute to the promotion and development of cost-effective uses of agricultural residues. Additionally, it can assist communities in achieving sustainable self-sufficiency, which is in line with our late King Bhumibol's economic sufficiency philosophy.


Should the Muslim Brotherhood be considered a "terrorist" organization? By 2019, the president of the U.S. and several congressmen had floated the idea. The Brotherhood is proscribed by the United ...


Ischemic heart diseases are a group of diseases , most commonly atherosclerotic origin, affecting the coronary artery vessels and cause myocardial ischemia and myocardial tissue, whose clinical manifestations , mostly , are themselves a medical emergency. This article reviews the epidemiology of ischemic heart disease until 2013 and the prevalence of cardiovascular risk factors in Cuba .


Dynamic 3D garment simulation has various applications in many domains. Recently, self-supervised learning for this task has been studied to reduce annotation costs. However, different material characteristics of garments have been rarely explored, limiting the generalization and flexibility of existing methods. Therefore, in this paper, a novel self-supervised deep learning architecture is proposed, namely Material-aware Self-supervised Network (MSN), as a material-aware approach for dynamically simulating garments with different materials. Specifically, a material-aware parameterized regressor is introduced based on the observation that material characteristics change continuously regarding the fabric parameters. As a result, MSN realises real-time garment simulation with various material properties without model re-training. Moreover, to simulate garments of different categories (e.g., t-shirts vs. dresses), a sampling-based linear skinning strategy is studied in MSN. Comprehensive experiments on the widely used AMASS dataset demonstrated the effectiveness of MSN both quantitatively and qualitatively.


Objectives — This study was performed to examine the safety of reducing the long-term doses of furosemide administered to patients with congestive heart failure (CHF) stabilized on a standard medical treatment. Methods and results — Twenty-nine patients with advanced CHF were treated with enalapril, digoxin, nitrates, and furosemide, as needed to alleviate their symptoms, and remained clinically stable for at least 3 months on those doses. Subsequently, the daily dose of furosemide was reduced to 1/3 of the previous dose, while the concomitant therapy was unchanged. All patients underwent a thorough clinical evaluation and right-heart catheterization before and 2 months after the furosemide dose reduction. After the treatment optimization the NYHA functional class decreased from 2.3±0.6 to 1.4±0.6 (p = 0.000), and the left ventricular ejection fraction increased from 22±10% to 32±13%, (p = 0.000). Clinical and haemodynamic evaluation before and after 2 months of treatment with lower furosemide doses showed that 24 of the 29 patients (83%) remained in a stable NYHA functional class and maintained a stable haemodynamic status. In the remaining 5 patients (17%), mean NYHA functional class increased from 1.8±0.4 to 2.4±0.6 (p = 0.07), accompanied by a significant increase of the right and left ventricular filling pressures from 4.2±2.7 to 9.0±3.0 mm Hg, p = 0.018 and from 8.6±3.0 to 19.8±3.6 mm Hg, p = 0.017, respectively. These 5 patients returned to a stable clinical status upon resumption of the prior doses of furosemide. Conclusions — Most patients with chronic CHF who were clinically stabilized on high doses of furosemide remained stable on a maintenance dose equal to one-third of the dose needed for their stabilization. Patients unable to tolerate the dose reduction regained their previous clinical status following the resumption of the prior diuretic doses.


In this paper, we introduced methods for conducting Bayesian quantile analysis of an allometric model that included random effects, with the primary goal of estimating quantiles of the length‐weight relationship of fish data. We developed prior elicitation schemes to incorporate historical information into the analysis of current data. We proposed Gibbs sampler methods to facilitate Bayesian computation and provided detailed implementation schemes. We applied our methods to analyze data of walleye Sander vitreus and white bass Morone chrysops in Lake McConaughy, Nebraska. Copyright © 2011 John Wiley & Sons, Ltd.


The Moral Objection Now we turn to the other major objection to the SAA: the moral side of the debate. Critics argue that allowing illegal immigrants to pay in-state tuition prices would send the message that the U.S. rewards law-breakers, rather than condones them. Laws that exist specifically to prohibit illegal entry into the country would be undermined and illegal immigration will increase as a result. While not much evidence exists that proves most undocumented immigration is driven by a desire to obtain a free public education, a case can still be made. Todero states that because migrants are risk averse and because there is a great uncertainty attached to the probability of employment, employment outcomes carry a lot of weight in one's decision to immigrate. Since attending college increases one's chances of landing a job, it can be argued that foreigners would view the implementation of SAA as a factor that would increase their probability of employment, which would thus encourage them to immigrate to the United States. If the SAA does indeed encourage illegal immigration, a dire economic situation could result. After taking into account projected emigration and death rates of 1.5% and .5%, respectively, the Carrying Capacity Network projects the stock of illegal settlers to increase by an average of 300,000 per year based on 1997 estimates of the Immigration and Naturalization Service (Huddle). Using estimates of illegal alien stocks of 4 to 5.4 million and growth by 300,000 yearly, we find that the net costs of public assistance for illegal immigrants and the U.S. workers they displace will be between $207 and $280


Female mice, like premenopausal women, are generally protected from the insulin resistance and inflammation associated with obesity. With aging and menopause, levels of estrogens fall and women tend to gain body fat and become as susceptible as men to obesity-related metabolic diseases. In male mice, high-saturated-fat diets cause obesity, systemic insulin resistance, and adipose tissue inflammation, especially in gonadal fat depots where adipocyte death is associated with macrophage infiltration and activation. Female mice also gain body fat on high-fat diets, although they exhibit much lower levels of adipose inflammation and insulin resistance (1, 2). This sex difference is not likely entirely attributable to estrogens because high-fat feeding of ovariectomized female mice does not increase adipose death to levels seen in high-fat-fed males (1). Over and above female sex, a lower-body or gynoid fat distribution further protects women from metabolic disease (3). Thus, mechanisms linking the biology of specific fat depots to sex differences in metabolic risk are of great interest for translational research.


The Enzyme Linked Immunosorbant Assay (ELISA) for Thyroid Peroxidase (TPO)autoantibodies (aAbs) is a useful clinical test for diagnosing human thyroid conditions. In this study experiments were carried out in order to improve two aspects of the TPO ELISA produced by The Binding Site Ltd. Firstly, modifications were made to the TPO ELISA in order to improve its calibration curve gradient. Secondly, the ability of the TPO ELISA to return consistent results over time was analysed and improved. All modifications made to the TPO ELISA during the study were to adhere to practical and economic restrictions made by The Binding Site Ltd. Results show that improvements to the calibration curve of the TPO ELISA could be made by modifying the way the assay is produced. However, these changes drastically increase the cost of the test, making them industrially unviable. It was also shown the reproducibility of the TPO ELISA was improved through the use of a national reference material.


Objective: To estimate the rates of mental illness among edicaid beneficiaries with traumatic brain injury (TBI) and ssociated Medicaid-paid expenditures. Design: Retrospective claims-based calendar year data. Setting: Claims data. Participants: Medicaid recipients with diagnosed TBI and ental illness who received Medicaid services in 4 states in 995. Interventions: Not applicable. Main Outcome Measures: Annual expenditures for total, npatient, and noninpatient services, as derived from Medicaid ersonal summary files. Mental illness and TBI were identified y using International Classification of Diseases, 9th Revision, linical Modification codes recorded in Medicaid claims. Results: Of a total of 493,663 Medicaid recipients, 3641 0.7%) were diagnosed with TBI in the 4 states. Significant emographic and racial differences were found in the rates of BI; 18% of patients with TBI were diagnosed with serious ental illness. People with TBI in the age group 40 to 49 years ere more likely to have a mental disorder. There were sigificant differences in estimated total, inpatient, and noninpaient expenditures between those with and without mental llness. In general, those with serious mental illness had higher edicaid-paid expenditures than those without any mental llness. Conclusions: Psychiatric comorbidity in TBI increases the verall expenditures in this population. This increased cost is n important consideration in programming for those with TBI.


The shift from the 20th to the 21st century has brought about a multitude of technological developments, particularly in the education sector. However, the recent COVID-19 pandemic has created substantial obstacles for students, not limited to but including economic difficulties, the digital divide, and lack of resources. Nevertheless, the pandemic also allowed for the flourishing of artificial intelligence (AI) & machine learning technologies, which can be utilized to mitigate these issues in education. This paper explores how AI & machine learning have been used to innovate current education institutions — including programs such as Educational Data Mining, Intelligent Tutoring Systems, and Adult Learning Systems among others — as well as the drawbacks to this approach and potential future applications for these technologies. Naturally, as a developing field there are many objections surrounding these technologies due to concerns such as data privacy, loss of soft skills, barriers to implementation, and more. But in spite of this resistance, many AI-driven educational initiatives have thrived. By analyzing past successes and failures, we hope to provide guidance for better employing these technologies in education in the future.


Type of funding sources: None.

 In 2020, the Japanese government issued a new policy to facilitate telemedicine to prevent spread of SARS-Cov-2 infection in outpatient of medical facilities. This policy included consultation via telephone or web and issuing prescriptions directly to pharmacies. However, the patients with diabetes mellites usually have few symptoms. Accordingly, evaluation of control status and medical feedback is difficult on telemedicine basis. We sought to evaluate the impact of telemedicine on the treatment of DM in patients with cardiovascular disease during SARS-Cov-2 Pandemic period.

 Between April and Oct 2020, 165 patients with cardiovascular disease having diabetes mellites utilized telemedicine. We retrospectively analyzed indices of patients' condition and compared them before and after telemedicine. These indices included serum blood sugar, hemoglobin A1c, HDL, LDL cholesterol and triglyceride.

 Mean age of the patients was 74.0 ± 9.6 years. Average interval of telemedicine was 6.6 ± 3.4 months. The value of HbA1c before and after telemedicine period was 6.7 ± 0.9 and 7.0 ± 1.2 % respectively (p=0.006). No statistical difference was observed in systolic/diastolic blood pressure, HDL LDL cholesterol and triglyceride during same period.

 In telemedicine for the patients with cardiovascular disease, additional caution is needed when patients had concomitant diabetes mellites.


The aim. Study of the features of retrochoir hematomas (RHG) and their influence on the formation of the placenta, the course of pregnancy, as well as the occurrence of premature birth.
Materials and methods. 2 groups of pregnant women were selected depending on the frequency of RHG formation: 1 group – 60 pregnant women with recurrent RHG, group 2 – 50 pregnant women with RHG, which was detected only in the early stages of pregnancy. extragenital and genital pathology did not differ reliably. All the women studied were anamnesis, examined, and ultrasound and dopplerometry were performed.
Statistical methods included an assessment of statistical significance using Student's t-criterion and criterion X2 and were considered significant at p<0.05.
Results. Supracervical localization of hematomas prevailed in the studied pregnant women, namely: in group 1 – 51.7 % (in 31 pregnant women) and 68 % (in 34 women) in group 2. The same pattern was observed regarding the involution of hematomas.
Changes in the yolk sac were found in both groups with RHG (in 6.7 % of women (i.e., in 4 pregnant women) of group 1 and 4 % (in 2 pregnant women) of group 1.
Mean values of the pulsation index (PI) of blood flow velocity curves in the uterine arteries (UA) and umbilical cord artery (UCA) in pregnant women with RHG were higher than the standard average for gestational age.
In pregnant RHGs, a history of various types of fetal growth retardation (FGR) is detected. The number of early forms of URP was higher in group 1 (16.7 %, i.e. in 10 pregnant women) as opposed to group 2 (2.0 %, i.e. 1 case). The late form was approximately the same amount in both groups. Also, group 1 was characterized by a significantly larger number of FGR of 2-3 centuries.
In addition, in both groups with RHG, such pathological conditions were identified during pregnancy as the threat of premature birth, premature placental maturation, placental hypoplasia, oligohydramnios, and hydramnios.
Conclusions. Pregnant women with recurrent RHG compared to pregnant women with sporadic RHGs have a greater number of complications during pregnancy, including the threat of preterm labour, premature placental maturation, placental hypoplasia, oligohydramnios, hydramnios, FGR, impaired uterine-placental and placental-fetal blood flow.


Adolescents who live in the orphanage usually don't live with their own family for a variety of reasons. Separation and disappointment with the family often make them hard to show gratitude. Previous studies show that there is a correlation between religiosity and gratitude. But even when they were educated in Christian orphanage that has a routine religious activity, many are found has a hard time to show his or her gratitude. By this research, author wanted to find out the influence of religiosity to gratitude, also the influence of each dimension of religiosity to gratitude. This study used The Four Basic Dimensions of Religiousness Scale and Gratitude Questionnaire – 6 Item Form. The participants of this study are 88 Christian adolescents who live at Christian orphanage, which are 11-20 years old. The result of this study shows that there is a significant influence of religiosity to gratitude (R2= .176, p= .003), with the most significant influence of religiosity's dimension is behaving (B= .302, p= .019).


All professions foster an identity among practitioners. Physical education is no different. How this identify influences and is expressed throughout one's life and lifestyle is a topic not seen in our literature. In this essay, I provide a perspective for those entering as well as those engaged in the profession to reflect on the scope of being a physical educator. I'll start with my beginning in the profession.


Abstract Owing to the great versatility offered by polyurethanes regarding the ease of synthesis and variable properties of the final product obtained (elastomeric or rigid polymer), polyurethanes become a basic component used in IPN formation. Numerous studies were conducted on IPNs based on polyurethanes and various vinyl monomers. Tensile strength, hardness, swelling, and thermal properties were obtained, and morphology studies have been conducted. This review gives a comprehensive compilation of the recent studies on these properties. The article specifically deals with the systematic coverage of all the research work carried out in the field of interpenetrating polymer networks (IPNs) based on polyurethanes (PUs) and various vinyl monomers.


SummarySouthern Guangxi, Chinahasone ofthehighest incidences ofhepatocellular carcinoma (HCC)in theworld. Serumsamples collected fromsubjects ofan earlier case-control study (39cases,41controls) and froma randomsampling ofa residential malecohort (n= 100) were tested forantibodies forthehepatitis C virus (anti-HCV) using ELISAversion 2.0withconfirmation byRIBAversion 2.0.Onlyone of141(0.7%, upper95%confidence limit, 3.2%) control subjects andnone of39(upper 95%confidence limit, 6.07%) HCC casestested positive foranti-HCV. Ourresults indicate thathepatitis C infection isnotan important environmental determinant ofHCC risk inthis hyperendemic region. Hepatocellular carcinoma (HCC)varies widely inincidence worldwide. Itisa relatively raremalignancy intheUnited States andmostofwesternEurope, butisone ofthe commonestcancersinlarge partsofAsiaandsub-Saharan Africa (Parkin etal.,1992). InthePeople's Republic of China,livercancer represents the thirdand fourth commonestcauses ofcancer deathinmen and women respectively (Liet al.,1979).Thereisconsiderable geographical variation inHCC incidence within China, the high-risk regions aremostly inthesoutheastern cornerofthe country withsouthern Guangxi exhibiting one ofthehighest ratesofHCC incidence intheworld. InFusuiCountyin southern Guangxi, thestandardised incidence rateofliver canceramong men is120per 100000population per year, whichis50timeshigher thanthecomparable rateinUS whites (Yehetal., 1989; Parkin etal., 1992). Previously, we haveshownthatchronic infection withthe hepatitis B (HB)virus isa primary riskfactor forHCC in southern Guangxi. Ina cohort study ofyoung andmiddle- agedmen infive rural communities insouthern Guangxi, we demonstrated thatapproximately one-quarter ofthemale population arechronic HB carriers, andthatliver canceris responsible forhalfofalldeaths inadult men. Over90%of subsequent HCC caseswere tested positive forhepatitis B surface antigen (HBsAg) atrecruitment, andtheincidence of HCC among HB carriers was close to1% peryear(Yehet al., 1989). Therewas alsostrongsuggestive evidence that dietary aflatoxin, primarily through ingestion ofmouldy corn,isan important cofactor inliver cancerdevelopment in Guangxi. We observed a 3.5-fold variation inHCC incidence between thefiverural communities whichconstituted our cohort, although these subpopulations displayed comparable prevalence ofHBsAgpositivity. However, repeated dietary andfoodsurveyshaveestablished thatthese communities differed intheir mean exposurelevels toaflatoxin B1,froma highof51.8 mg per personperyeartoa lowof0.3mg per personperyear.WhenHCC rates inthese communities were plotted against their mean loadofaflatoxin Bi,an almost perfectly linear relationship was noted(Yehetal., 1989). Relatively little isknownabouttheroleofhepatitis C infection inHCC development insouthern Guangxi. Okuno etal.(1994) tested 186(168men, 18women)patients with HCC and48control subjects (30men, 18women)for antibodies to thehepatitis C virus(anti-HCV) usinga second-generation, Abbott-manufactured enzyme immunoas- sayandnotedpositivity ratesof5.4%and0% respectively. Theirfindings contrast withthoseofZhangetal.(1994) whousedChinese-manufactured


This chapter describes that a martyr is not one who merely expires, not even a 'good person' about whom words are inadequate to express our love, respect, and admiration (particularly so, now that the person is dead). The majority of Luther's hymns were intended for congregational worship, and for most of them he adapted known tunes. Luther directed his response to reformation followers not only in Riga but also in Tallinn and Tartu, another city in Estonia. Two principal ways to embolden readers are to offer eulogistic narratives of the heroic deeds of the martyred and to use Scripture to remind readers of the promises they have in Christ. In the martyrological literature Luther uses the letter, the song, the narrative, and the exposition of Scripture to comfort his readers and celebrate Christ's victory.Keywords: Christ; congregation; hymns; martyr; scripture; Tallinn; Tartu


This paper illustrates the great significance of incorporating stream media technology into current distance education. The development, scale, weakness of distance education will be analyzed first. The advantages of the emerging stream media technology, which can effectively compensate the weakness of the current situation of distance education, will then be shown. Finally, the significance of the perfect combination of stream media technology and distance education will be discussed.


Model checking of safety properties is fundamental in formal verification. When a safety property is found to hold, the model checker provides (at best) a machine-checkable certificate that gives limited insight to users and little confidence that the check passes for the "right" reasons, rather than due to e.g., vacuity or unjustified assumptions. Recently, inductive validity cores (IVCs) have been developed to address this issue. In this paper, we lift several algorithms from the field of UNSAT core extraction in order to compute minimal IVCs of hardware safety checking problems. The MARCO algorithm extracts all minimal cores of an UNSAT formula by efficiently exploring the formula's power set, and has already been applied to compute IVCs in software safety checking. The CAMUS algorithm for UNSAT core extraction exploits a duality between minimal correction subsets (MCSes) of a formula and minimal UNSAT cores. We adapt the algorithms to the hardware IVC context, construct a hybrid algorithm that subsumes both CAMUS and MARCO, and introduce novel domain-specific optimizations. Several instances of the hybrid algorithm are presented (including CAMUS and MARCO themselves, among other novel variants) and evaluated empirically on hardware model checking competition circuits, demonstrating the practicality of the proposed algorithm.


First from defining the concepts of "development" and "ethnic development",this paper points out that the ethnic development is the whole and systematic change of ethnic social form,especially the change from traditional society into modern society.The paper further analyzes the subjective,historical,cultural,and homogeneous features of ethnic development and summarizes the theories of ethnic development after liberation,that is,from the theory of political equality to unbalanced economic development and to an over-all harmonious development,and gives them brief comments.It is pointed out that to promote the theoretical innovation of ethnic development,attention should be given to its subjective position,cultural reconstruction,and human value increase.


The semi-classical method for calculating the observable properties of light scattered from an optically thin atomic vapour is placed in the context of the well known input-output relations for random signals transmitted through a linear system. The autocorrelation of the scattered field amplitude, the statistic from which the mean intensity spectral density and intensity fluctuations may be deduced, is expressed in terms of the autocorrelation of the incident optical field and the autocorrelation of the scattering system; these latter are quantities that can be readily measured or calculated. An appendix contains a classical and a semi-classical calculation of the scattering system autocorrelation function for a vapour of atoms optically excited from a J=0 level under the conditions of a level crossing experiment. In the course of this calculation the relationship between the matrix element of the electric dipole moment operator and the corresponding classical quantity is carefully examined.


The invention relates to a bioactivator preparation method, in particular to a placenta polypeptide preparation method. The placenta polypeptide preparation method comprises the steps of cutting a placenta into pieces, and adding normal saline into the cut placenta for tissue homogenate; mixing the obtained product with protease for enzymatic hydrolysis, and performing centrifugation and collecting centrifugate; performing extraction through reverse micelles to produce placental polypeptides and crude protease extract, subjecting the crude protease extract to ultrafiltration, collecting ultrafiltrate, and drying the ultrafiltrate to produce the placenta polypeptides. The preparation method is simple, production cost is low, equipment investment is little, and large-scale production is facilitated.


The present study was aimed at evaluating the number of bacteria and fungi in the indoor environment of Federal University Dutse Library. The sampling site was located in the University main reading room. Forty (40) air samples were collected in the month of June 2018. Air samples comprising of twenty (20) for bacteria and twenty (20) for fungi were taken twice a day; in the morning and afternoon. All the samples were analyzed for the concentration of bacteria and fungi using plate count method. The average bacterial and fungal counts in the library were found to be 240.10 CFU/m 3 and 280.60 CFU/m 3 respectively and ranged from 132-345 CFU/m 3 for bacteria and 180-416 CFU/m 3 for fungi respectively. Having subjected the generated results to statistical analysis (T-test at 95% confidence limit), there was no significant difference between microbial loads recorded for bacteria and fungi (p-value=0.000). However, the mean microbial concentration of the library indoor air was within a range which indicates intermediate level of contamination according to the guidelines established in 1993 by the European Community Commission. It is therefore recommended that the surfaces of the library should be kept clean and dry, as the wet condition in the library can cause growth of pathogenic microorganisms. Again, a follow up study is required with a view to detecting seasonal variations of the indoor microbial counts of the library. Keywords: Indoor air quality, pollution, bacterial counts, fungal counts


The lime fruits are known to contain high flavonoid compounds, in which
one of the effects of flavonoids is as antioxidant. This study aims to determine
antioxidant activity of lime juice by ABTS method (2,2-Azinobis(3-ethylbenzothiazoline) -6-sulfonic acid), and it also determine its total flavonoid
content.
The fruits were thoroughly washed and squeezed to obtain the juice. The
antioxidant activity was measured by ABTS method with visible
spectrophotometer at maximum wavelength of 753.2 nm to obtain IC
50
using
vitamin C standard as positive control. The presence of flavonoid compound was
identified with magnesium powder and concentrated HCl as reagent. The total
flavonoid content was determined by spectrocolorimetric method using AlCl3
reagent and rutin standard that results giving in rutin equivalent (mg RE/g
sample).
The results showed that lime juice had antioxidant activity with IC
50
value
of 55,99 µg/mL, whereas vitamin C standard had IC
50
value of 6,95 µg/mL. Lime
juice contain flavonoid compound and its total flavonoid content was 0,13 mg
RE/g sample.


This paper describes a new Ku-Band product which is a state-of-the-art size reduction in 12- 18 GHz Ultra-Low-Noise Traveling Wave Amplifiers. This single-reversal-permanent-magnet focused unit weighs 6.5 pounds with integral power supply--slightly more than one-third the size and weight of equivalent noise present-day permanent-magnet focused traveling wave amplifiers.


Abstract By reaction of M(CO)6 (M = Cr, Mo, W) with the bifunctional aminophosphane Ph(NEt2)P-(CH2)4-P(NEt2)Ph (L-L) octahedral complexes (CO)4M cis(L-L) are obtained. While it is shown by 31P{1H} NMR spectroscopy, that these complexes contain meso-and rac-(L-L) to a different extent, there is evidence from 13C{1H} NMR data obtained for the Mo complex, that the rac-ligand always prevails. As racemisation is observed when the Mo complex reacts with HBr to give (CO)4Mo-cis[Ph(Br)P-(CH2)4-P(Br)Ph] an SN1-mechanism is suggested for this reaction.


Introduction: WNT16 is an important gene in bone homeostasis, found in a very complex locus that also includes neigh‐ boring genes: ING3, FAM3C, and CPED1. In addition to the clear role of WNT16 in determining bone mineral density (BMD), evidence has also been found for the importance of these three neighboring genes in bone metabolism. Therefore, it remains to be clarified whether the variants in WNT16 associated with BMD carry out their effect on WNT16 or if they do so by modifying the expression of these neighboring genes. Material and methods: We have determined the expression levels of CPED1 and FAM3C in primary osteoblasts and we have verified whether WNT16 variants behave as loci of quantitative expression traits (expression quantitative trait loci; eQTL) of these genes. Results: The amino acid change variant rs2908004 in WNT16 acts as the eQTL of FAM3C in primary osteoblasts under the dominant model hypothesis. Discussion: It is possible that the effect of this variant on BMD is due to the modification of the expression levels of FAM3C in addition to or instead of a direct effect of the mutant WNT16 protein resulting from the amino acid change.


This paper's main thesis is that Chile's developmental performance of recent decades was underpinned by significant and systematic institutional change, and that this change is closely related with its transformation from a state-centered society to a market centered one. The analysis will focus on the changing process in a set of institutions highly relevant for economic growth and social redistribution. In this regard, our interest is to specify the mechanisms that account for continuity and discontinuity in institutional structure, which according to some relevant authors is an important target of economic sociology (Nee and Swedberg, 2005). Additionally we will also discuss the impact of these changes over socioeconomic development.


A new bandwidth efficient interleaver is described for turbo codes when used to decode short frames of data using the MAP algorithm. Applications in rate compatible turbo codes and encryption are presented.


Xylan was prepared from bagasse and was hydrolyzed with 0.1_??_10% H2SO4 at 100° under atmospheric pressure. The optimum condition for the preparation of xylose was pursured. Then the preparation of xylose from bagasse was conducted as follows: 1kg of powdered bagasse was treated with 1% NaOH solution at room temperature for 1_??_2 days, washed thoroughly with water and hydrolyzed for 2_??_6 hrs. with 4_??_8% H2SO4 at under normal pressure. It was found that 70_??_75% of the total amount of the sugars formed was pentose. The crude crystals of xylose were obtained very easily without the use of CH3COOH or C2H5OH. In order to raise the sugar concentration of the hydrolyzate, the solution after saccharifications was repeatedly utilized for the the following process of hydrolyzing the bagasse. The sugar concentration was raised from 2.5% to 7.3% after the 4th repeated hydrolysis.


Increasing globalization and international trade in India let a number of international brands to enter into India, which is one of the fastest growing and highly competitive markets in the world. Most of the international brands who entered into Indian market fail Though, most of the global firms failed to understand the needs of Indian consumers as well as the market characteristics but there are a few of them who have been successful in positioning their brands into the Indian market. This research is an attempt to investigate why some international brands, are successful in India market by torching upon their marketing strategies, with special reference to Coca Cola & Pepsico.


The new regulations about the husbandry of laying hens and the so-called genomic revolution offer both opportunities and challenges for the breeding of layers. Hens are currently housed mainly in battery cages of 4 individuals each. Following recent developments of the communitarian legislation, many countries will soon adopt furnished cages or non-cage systems, which will lead to larger groups of hens. Also, beak-trimming will be prohibited in EU countries in the near future. Advancements in sequencing technology are making an always greater number of genetic markers available at increasingly cheaper prices, making genome-wide studies possible and helping geneticists to start unraveling the mystery of the genetic make-up of animals, which until a few years ago was considered a black-box. This thesis touches upon the impact of such innovations on the breeding of laying hens. Use of pooled data in the genetic evaluation of laying hens Hens are usually housed in cages and therefore pooled instead of individual egg records are often available: a pooled egg record is the total production of a cage, when the egg production of the individual hens is unknown. Current selection schemes are carried out in nucleus herds where hens are housed individually, so that egg production of individual birds can be recorded and used for genetic evaluations. Based on this information sires and dams are selected. Such a selection scheme based on individually housed hens introduces a discrepancy between the environment where hens are selected and the environment in which hens are kept for commercial egg production (group housing). Selecting animals in one environment and using them in a different environment might lead to genotype x environment interaction (Besbes and Ducroq, 2003), thereby reducing the realized response to selection. Future husbandry conditions, with larger groups of hens or hens housed in furnished cages might make this problem even worse. A method to use pooled data in the genetic evaluation of laying hens would therefore be of interest. In Chapters 2 and 3 of this thesis it is described how to use pooled records for the estimation of heritability and breeding values. In chapter 2 the use of individual and pooled observations is compared. Individual body weights of hens at different ages were available: these were then pooled by cage in order to create pooled records. Heritabilities estimated from pooled and individual data correlated well: the standard error of estimates based on pooled records was however about twice that of estimates based on individual records. The accuracy of EBVs from pooled data is lower than the accuracy of EBVs from individual data; in the case of sires with at least 10 offspring the reduction in accuracy was about 23%. This loss of precision in estimating genetic parameters and breeding values is understandable considering that pooled records are a less detailed of information. However, this lower accuracy should be interpreted in the context of direct vs indirect selection. The breeding goal is the trait under commercial conditions (group housing), and if testing is under individual housing, the genetic correlation between group and individual housing is relevant. The ratio of the selection response for direct and indirect selection is a function of the accuracies for both situations, the standard deviations of the traits and the genetic correlation between the traits (Falconer, 1989). Similarly, the ratio between accuracies based on pooled and individual data provides a threshold for the genetic correlation between individual and group housing below which pooled data would result in a greater selection response. In practical breeding also the costs of individual housing relative to the costs of group housing are relevant. Since group housing is cheaper than individual housing, more selection candidates could be tested for the same level of costs. This would in turn result in higher selection intensity and larger response to selection. In chapter 3 the method of analyzing pooled data developed in chapter 2 was compared with an approximation consisting in assigning cage means to each hen in a cage, then treating them as individual observations. Cross-validation was used to compare the two methods: the method developed in Chapter 2 performed consistently better than the approximate method in terms of predicting ability. In the general discussion, finally, it was described how to estimate genetic and phenotypic correlations from pooled data. Across-line association studies for immune response and feather pecking behaviour The great number of genetic markers available at increasingly lower prices has been fostering developments in genomic research. Association studies between genetic markers and phenotypes are typically conducted within populations (breeds, or lines): the amount of LD conserved in a population is exploited using high marker density, such as SNP chips, and markers relatively close to QTLs are expected to show significant effects in association studies. In this thesis we propose to take it one step further and perform association studies across lines. This requires higher marker density but increases the resolution. The amount of LD conserved across lines is expected to be lower than within lines and the phase of the marker-phenotype association might be different in the different lines. On the other hand markers that happen to show significant effects in an across-line association study are likely to be close to the QTL. These issues in conducting marker-phenotype association studies across populations were addressed in Chapters 4 and 5 of this thesis, where it was shown how to deal with multiple populations when analyzing hens from 9 different genetic lines of White Leghorn and Rhode Island Red origin genotyped for a panel of 1536 SNP (Single Nucleotide Polymorphism) markers. The traits analysed were immunological parameters and plumage damage due to feather pecking behaviour, two classes of traits for which, given that they have relatively low heritability and are difficult and expensive to measure, genomic information may be particularly valuable. Immunological parameters might be used in selection programmes aimed at improving disease resistance of laying hens, while information on the genetic background of feather pecking behaviour can be useful in reducing problems due to this behavioural disorder of layers. Under future husbandry conditions susceptibility to infectious diseases and feather pecking are expected to become more serious problems: both aspects of layer production are in fact related to the number of individuals that interact with each other, which will increase as a result of the application of the EU directive 1999/74/EC. In addition, the ban of beak-trimming will make it more difficult to control the consequences of feather pecking (plumage damage, cannibalism, mortality). Genetic selection might represent an appealing addition to the current control measures. The association studies identified several regions of interest. The gene for interleukin 17 (IL17), on chromosome 3, was found to be associated with natural and acquired antibody titres, and with the classical and alternative pathways of complement activation. The major histocompatibility complex (MHC) genes on chromosome 16 showed significant association with natural and acquired antibody titres and classical complement activity. The interleukin 12B gene (IL12B) on chromosome 13 was associated with natural antibody titres. As for feather pecking behaviour, a role of the gene for the serotonin receptor 2C (HTR2C) on chromosome 4 was found. This supports existing evidence of a prominent involvement of the serotonergic system in the modulation of this behavioural disorder in laying hens. The genes for IL9, IL4, CCL4 and NFKB were found to be associated to plumage condition, revealing relationships between the immune system and behaviour.


We have investigated the charge dynamics of VO2 by optical reflectivity measurements. Optical conductivity clearly shows a metal‐insulator transition. In the metallic phase, a broad Drude‐like structure is observed. On the other hand, in the insulating phase, a broad peak structure around 1.3 eV is observed. It is found that this broad structure observed in the insulating phase shows strong temperature dependence. We attribute this to the electron‐phonon interaction as in the photoemission spectra.


Six grain samples namely barley, maize, millet, rice, sorghum and wheat were tested for enzyme levels (amylase, protease and lipase) in order to assess their malting characteristics, using barley as a standard. The levels of the enzymes were estimated in the whole dry grains, 24h steeped, 24h sprouted and 48h sprouted grains. A combined statistical analysis of linear regression and analysis of variance were used to test for enzyme interaction, similarities and interspecific relationship between the cereals. The estimated interspecific relationship between sorghum and barley was 84% based on the three enzymes, while millet had 75%. All the sprouted cereals with the exception of the standard barley had high lipase levels. This possibly suggests certain limitations as regards to production of off-flavours. Malt prepared from maize, sorghum, rice and millet had comparable protease levels with barley (P>0.05). The malts prepared from maize, millet, rice, sorghum and wheat had comparatively low alpha-amylase levels when compared with the standard barley. Multiple linear regressions showed amylase was dependent on lipase and protease. The relationship was not affected by either soaking (steeping) or sprouting of the grains. The implications of these findings suggest that a combination of these cereals might give good malt for food applications.


This paper gives some new results in sequential hypotheses testing. The observable process should have continuous sampling paths. The minimum information criteria are reached with the fixed probabilities of wrong recognition.


smear-word, but I do not agree that the salient feature of that passage is 'Ar.'s emphasis on social distinctions based on wealth and breeding'. In fact it contains virtually no reference to either wealth or breeding (506 ftiov yewaiov is vague), and one of the persons ' smeared' is actually a slave (500-2). The emphasis is rather on individuality and refusal to conform to popular tastes and customs. 643-5: H. follows the text and interpretation proposed by Stinton, but fails to consider the subsequent discussion by M. B. Walbank, CQ 31 (1981), 276-81. 720: The hole can hardly be 'on the roof. It must be some kind of gap in the rocks through which one could descend from the top of the Akropolis by way of Pan's grotto. 833: What is ' hieratic prosody'? 846: The statement 'The torture of slaves and criminals was...not infrequent in classical Athens' is over-confident, and is not supported by H.'s two references, of which one (A. Eum. 185ff.) does not refer to classical Athens and the other (PI. R. 439e) refers to execution, not torture. There are few known instances of torture in this period. 870: 'We hear Myr.'s voice before she appears' begs a question about the audibility of voices offstage in the open-air theatre. Myrrhine may equally well be visible on the roof of the skene. 1125: The line means not 'I am of an age to have a worthwhile opinion', but ' I am, of myself (by innate ability, without help from others), fairly intelligent'. 1128: It is not true that Lysistrata's speech is the longest in Ar. since Knights. Wasps 83-135 and Birds 1277-1307 are longer, with no interruptions; if short interruptions are ignored (as by H. here), some speeches in agones are longer still. 1189-94: Not only girls are to be equipped, for rots -rraiaiv is masculine.


The object of the present article is to re-state two obscure problems and to show that their likely solution can be found only in tṛeating them jointly. The two points are: the name of the ancient capital of the Ās (Alāns, now Ossets), as attested in the tenth century, and the identification of the town *MKS conquered by the Mongols in the course of the campaign of 636/1239. As the sources on the latter event are more numerous I shall deal with it first. On the Muslim side we have two accounts of Batu's campaign, that of Juvaynī who completed his work in 658/1260, and that of Rashīd al-dīn, who wrote about 710/1310.


The Crouzon's Syndrome is a rare genetic disorder, with an incidence between 1/25,000 to 1/100,000 newborn babies, transmitted autosomal dominant, characterized by facial dysmorphism and craniosynostosis, based on those characteristic can be diagnosed early. We present the case of a premature newborn female admitted to the Hospital Division of Neonatology "Louis Ţ urcanu" with facial dysmorphism. The anamnestic investigation revealed that the patient's mother and sister suffer from the same type of affection. The patients affected by Crouzon Syndrome have a normal lifespan, and 97% of them have a normal intelligence. The quality of their life is affected by aesthetic considerations and the severity of abnormalities they present.


This paper provides empirical evidence and theoretical grounds to support the existence of energy cost constants, i.e., relatively stable energy costs to income ratios, not only country-wide, but also in major energy end-use sectors. These ratios are similar across different countries at different stages of economic development, but they also depend on the country-specific economy structure and legacy of previous long-standing energy pricing, taxes, and subsidies policies, which it takes time to shift from. The aggregated country-wide energy costs constant (range) is a linear combination of those for sectors weighted by the contributions of respective sectors' income indicators to either gross output or GDP. Deviation of energy costs shares from the constrained range is possible but limited. The "rule of gravitation" goes: for the whole cycle real energy prices in each sector may grow only as much as energy intensity declines, and inversely promoting energy efficiency can be viewed as a policy, of which the environmental cobenefits will be undermined by rebound effects, unless it is accompanied by rising energy prices.


A research program was undertaken to explore the potential and practicality of developing active control Helmholtz resonators to attenuate excessive turbofan engine noise. The active Helmholtz resonator provides increased acoustic bandwidth by adding a controlled velocity via a secondary sound source. Plane wave tests demonstrated that the concept could be used both the increase a resonator's absorption bandwidth and induct insertion loss bandwidth. For effective absorption of sound in a two dimensional duct environment, the active resonator concept was combined with a unidirectional radiation technique, which was extended to provide simultaneous suppression of multiple azimuthal, multiple radial and multiple blade-pass harmonic sound fields. The program culminated in a demonstration in the ANCF at NASA Glenn Research Center


The 13th century Eyrbyggja saga is one of the most important Icelandic sagas, but also one of the most discussed because of the seemingly heterogeneous elements of its plot, which unfolds it as a chronicle. The present study takes as its starting point the central significance of the god Thor in his function as the founder and preserver of culture for the community of settlers, and attempts to develop the ideas connected with the establishment of an ordered community life for the medieval Icelanders. The thematic foci are provided by the occupation and settlement of land and the complex discourse of sacrifice in the saga.


This study covers the attempt to incorporate a proposed knowledge discovery framework in an open world Intelligent Game-Based Learning Environment (IGBLE) to further improve the use's experience. Four phases were done in order to come up with the framework: (1) sequential pattern mining using PrefixSpan of user's action log, (2) association rule mining of the generated patterns, (3) extracting generic rules using Informative Generic Base (IGB) algorithm and (4) integrating it to the IGBLE. The framework produced a learned Procedural Task Knowledge (PTK) that served as a mechanism to support tutoring for the selected game. This implies that the new IGBLE incorporated with the framework provided significantly better guidance to the players through recommending good and easy-to-follow sequences of actions.


In this paper, we investigate a weighted Dirichlet eigenvalue problem for a class of degenerate operators related to the \begin{document}$ h $\end{document} degree homogeneous \begin{document}$ p $\end{document} -Laplacian \begin{document}$ \begin{equation} \nonumber \left \{ \begin{array}{ll} {|Du|^{h-1}}\Delta_p^N u+ \lambda a(x)|u|^{h-1}u = 0, \quad\quad \rm{in}\quad \Omega, \\ u = 0, \quad\quad \quad \quad \rm{on} \quad\partial\Omega. \end{array}\right. \end{equation} $\end{document} Here \begin{document}$ a(x) $\end{document} is a positive continuous bounded function in the closure of \begin{document}$ \Omega\subset \mathbb{R}^n(n\geq 2), $\end{document} \begin{document}$ h>1, $\end{document} \begin{document}$ 2 and \begin{document}$ \Delta_p^N u = \frac{1}{p}|Du|^{2-p} {\rm div}\left(|Du|^{p-2}Du\right) $\end{document} is the normalized version of the \begin{document}$ p $\end{document} -Laplacian arising from a stochastic game named Tug-of-War with noise. We prove the existence of the principal eigenvalue \begin{document}$ \lambda_\Omega $\end{document} , which is positive and has a corresponding positive eigenfunction for \begin{document}$ p>n $\end{document} . The method is based on the maximum principle and approach analysis to the weighted eigenvalue problem. When a parameter \begin{document}$ \lambda , we establish some existence and uniqueness results related to this problem. During this procedure, we also prove some regularity estimates including Holder continuity and Harnack inequality.


An idea on designing intrinsically electrical conductive textile-based strain sensor is presented in this paper. Textile structure endows this sensor flexible, deformable, breathable property that is really wearable. The sensing mechanism is investigated theoretically and experimentally to find the guidelines when designing a textile strain sensor. The electrical conducting mechanisms of yarn and fabric are modeled by using circuit network to analyze the key elements contributing to the fabric sensor. It is found that the contact resistance, which is caused by two contacting fibers or yarns, created and determined by the structures of fabric, is the key factor contributing to the sensing mechanism.


New industrialization puts forward new requirements to higher vocational education. In order to adapt to the needs of new industrialization, the construction of campus culture in higher vocational colleges must be fused with the enterprise culture and vocational culture. The general thought of this kind of fusion is based on the guide of the socialist core values, the enterprise culture and vocational culture with the essence of dedication to work and good faith, and the spirit of the time with the core of reform and innovation.


We measured the heart rate before, during and after a 1200-m race, and blood lactate concentration at 10 min after a race in 23 Thoroughbred horses. The heart rate increased when horses were walking through the underground passage and after the jockeys mounted them in the paddock, even though there was no increase in exercise intensity. During the canter from the exit of the underground passage to the starting stalls, the heart rate increased to a peak value of194.0 ±2.0 (mean ±SE) beat/min, which was equivalent to 91.1 ±0.8% of the maximal racing heart rate. In the starting stalls immediately before the start of the race, the heart rate was 171.4 ±5.3 beat/min. The peak value of the heart rate (HR peak ) during the race was 213.6 ± 1.7 beat/min, and the time taken to reach 95% of HR peak was 12.4 ±1.8 sec. The blood lactate concentration after the race was 22.5±0.6 mmol/l. The mean speed of the horses was 15.9 ±0.0 m/s, which was similar to those of 3-year-olds in maiden races. These data could be useful for planning training strategies for Thoroughbred horses.


During the summer of 1935 and 1937, the writer made ecological studies of an acid stream, Daimyozinzawa, which rises near the top of lit. Azumaya-san, a dormant volcano (ca. 2100 m), and runs down the valley, through the Sugadaira Highland from northeast toward southwest, to a locality about 1100 m above the sea level, where it confluences with Karazawa, a neutral stream. The acid reaction of the water of Daimyozinzawa stream is due to the large amount of sulphuric acid, which seems to be derived from the acid soil around the source of the stream. The pH of the water is 4.9 at, Syowa waterfall, about the middle of the stream, 4.4 or more less at the upper part, and 7.0 at its lowest part.In the acid part of the stream there is no algae, which are usually abundant in some of the neighbouring neutral streams, while a moss, Seapania irrigua (NEEs) DuM., as an unique plant, covers the surface of the stones, submerged in the torrential water. Small quantities of algae, such as Nostoc and Sticliococcus, barely appear in the lower neutral part.Larvae of the water insects, Plecoptera (Nemura, Chloroperla, Isogenus), Tricoptera (Diplectrona, Rhyacophila), and Diptera (Simulium), live under the submerged stones of the acid part. Planaria gonocephala also is found there. Among the Scapania-vegetation, a larva of Chironomidae (Orthocladiinae) and a species of Nematoda abound.A striking feature is that nymphs of the ephemerids, which is an important member of the fauna of Karazawa stream, are never found hero not only in the acid part, but also in the neutral waters.


The commonplaces, all grammatically confused, are that 'conditionals' are ternary in structure, have 'antecedents' and conform to the traditional taxonomy. It is maintained en route that 'The bough will not break' is consistent with 'If the bough breaks …', that there is no logical difference between "future indicatives" and "subjunctives", and that there is a difference between the logic of propositions (e.g. 'The bough broke') and that of judgments ('The bough will/might/could/should/must/needn't break').


This Thesis is brought to you for free and open access. It has been accepted for inclusion in Dissertations and Theses by an authorized administrator of PDXScholar. For more information, please contact firstname.lastname@example.com. Recommended Citation Hauser, Allen Nolan, "Patterns in creativity : an examination of Viennese culture and politics at the turn of the century" (1988). Dissertations and Theses. Paper 3818.


A new fumigant consisting of 3 parts by volume of ethylene dichloride and 1 part by volume of carbon tetrachloride is very effective against stored product pests. It is cheap, non-inflammable, non-explosive, non-injurious to stored commodities and is not dangerous to human life. It is about five times as toxic as carbon tetrachloride.


Fossil fuels currently provide the bulk of world's primary energy. Since fossil fuels are nonrenewable natural resources and rate of its utilization exceeds the natural rate of production, an end point exists. There is thus a need for the development of new energy sources that will be more economically competitive. Water hyacinth (WH) and Sugarcane Bagasse can be used to generate energy which could save on the fossil fuels conventionally used as source of energy. In this study, the possibility was explored to mix water hyacinth with Sugarcane Bagasse in different combinations for anaerobic co-digestion, so that energy can be generated as biogas. In this work, different proportion (0%, 25%, 50%, 75% and 100%) of sugarcane bagasse and water hyacinth are going to be used for anaerobic digestion. The investigation will help to find the most proper ratio of different cosubstrate that provide an optimize biodegradation potential or enhance biogas potential.


Laurie Monahan: firstname.lastname@example.com "Believe it." With these words, Vogue's photographer and war correspondent in Europe, Lee Miller, flatly presented her most disturbing contribution to the magazine in June of 1945.1 Marking the celebration of Germany's surrender to Allied forces, both the U.S. and the U.K. editions of Vogue included Miller's photographs of the Buchenwald concentration camp in Weimar: a hanged man, beaten, identified as a prisoner; emaciated corpses piled on hard ground, one with eyes open, gazing vacantly at the viewer.2 The simple directive, generally unnecessary in the context of documentary reportage, indicates that Miller may have worried that the evidential certainty usually evoked by photographs could be doubted. Sensing the potential resistance to accept what they saw, Miller urged readers to comprehend and understand the truth of these photos. "Believe it." Two words succinctly point to the conceptual reversals required to make sense of the fantasy of fashion and the reality of the concentration camp. The editors were curiously compelled to describe what was clearly visible: "The photograph on the left shows a pile of starved bodies, the one above, a prisoner hanged on an iron hook, his face clubbed."3 Yet these descriptive efforts are decidedly unhelpful. They offer nothing to make sense of the images. Why starved, why stacked up? Why beaten, why hanged? Four lines from the cable Miller had sent were included:


This thesis examines the life and politics of Patrick Dollan a prominent Independent Labour Party (ILP) member and leader in Glasgow. It questions the perception of Dollan as an intolerant, Irish-Catholic 'machine politician' who ruled the 'corrupt' City Labour movement with an 'iron fist', dampened working-class aspirations for socialism, sowed the seeds of disillusionment and stood in opposition to the charismatic left-wing MPs such as James Maxton who were striving to introduce policies that would eradicate unemployment and poverty. Research is also conducted into Dollan's connections with the Irish community and the Catholic church and his attitude towards Communism and communists to see if these issues explain his supposed ideological opposition to left-wing movements.
The thesis will test these perceptions by examining Dollan's role within Glasgow Corporation, the Glasgow and Scottish Federations of the ILP and the public and voluntary organisations that Dollan was involved in. Full use is made of contemporary and socialist newspapers, Glasgow Corporation Minutes, ILP conference reports and minute books, public records and archives. The objective is to look at the growth and development of the Labour movement in Glasgow and establish whether Dollan was indeed a fetter on the 'forward march of Labour' or deserves recognition as someone who made a positive contribution to the labour movement by enhancing the lives of the Scottish working class.


The front end of a conical forward carbon-carbon heatshield is attached to carbon-carbon nose tip by a threaded connection. The nose tip provides rigid structural support for the small end of the heatshield at all conditions of thermal expansion. The joint between the aft end of the forward heatshield and the forward end of an aft carbon-phenolic heatshield includes a tolerance gap which is tapered to accommodate the vector movement of the carbon-carbon heatshield due to axial and circumferential thermal expansion. The gap is filled with a high temperature insulating washer of frangible material which is crushed by the axial expansion of the forward heatshield and evacuated by the slip-stream. The forward heatshield is supported at the joint by a segmented ring of high density carbon wedges that will expand during flight and move with the heatshield along an expansion ramp to provide continuous support.


With the popularization of computer and the improvement of multimedia technology, multimedia English teaching will be the trend of foreign language teaching. This paper probes into the feasibility of multimedia English teaching in higher professional education, and points out the features of this kind of education and some matters needing attention in multimedia education.


Today the manufacturing of piezomotors consists of various heterogeneous, evolving and it-isolated production processes. The main task of the middleware is to provide a simple, flexible and extendable method for the integration of all existing and future processes to a centralized information system. Then with this system it is possible to present filtered information for special applications like business control or quality analysis. In addition the message orientated middleware enables a communication between all processes which is the base for an automated manufacturing system.


The present invention relates to a method for producing a workpiece with modified gearing geometry by a rolling method by means of a tool with modified gearing geometry, wherein the machining of the workpiece is carried out by an axial rolling process with a topologically modified tool.


This study contains the results of measurement of the maturity of Information Security Management System (ISMS) in the Gresik District The result of measurement of the completeness and maturity of the ISMS in BPMP Gresik Regency is still relatively low, that is at the level of I to II which means the maturity level is stated in the initial condition up to the implementation of the basic framework, it is still under standard ISO 27001: 2009. And for the evaluation of the level of completeness of the implementation of the five areas with the achievement score of 207, then according to the Indeks KAMI mean readiness status is considered "Not Eligible". The causes of the low maturity level of the ISMS include low levels of awareness from the leadership and related employees of the ISMS, lack of documentation of activities and also for the development of applications and infrastructure that are reactive.Researchers suggest of things need to increase awareness to leaders and employees regarding the importance of the ISMS, and to develop ICT Blueprint that enables BPMP application development and infrastructure to be conducted in a planned and comprehensive manner. And improve SOP in BPMP environment to support business process shift from paper-based to technology-based administration as well as to cultivate the documentation of data and information in BPMP Gresik District. Keywords: ISMS, BPMP Gresik District, index KAMI, ISO2700:2009


Purpose
This study aims to address the existing gap in co-design frameworks by introducing the EMPOWER framework, a strength-based co-design methodological approach specifically designed to tackle the key empowerment challenges associated with co-designing alongside individuals experiencing vulnerability. The purpose of this study is to provide a set of easy-to-remember empowering guidelines to enhance the co-design process.

Design/methodology/approach
EMPOWER is based on lessons from the field, through five years of working with older adults.

Findings
The framework includes seven guidelines to overcome common challenges in co-design research. The acronym EMPOWER refers to guidelines for extending, multiplying, publicising, outsourcing, widening, enabling and reflecting on co-design research.

Research limitations/implications
Although extendable to other experiences of vulnerability, the examples provided focus on the experiences of ageing consumers.

Practical implications
EMPOWER has direct relevance to practitioners wishing not only to work with consumers experiencing vulnerabilities but also to empower these consumers through purposeful research actions.

Social implications
Although drawing on co-design research with older adults, these guidelines can be applied to empower other groups experiencing vulnerability.

Originality/value
There is a relative lack of guidelines on how to strengthen the co-design process in a way that empowers consumers experiencing vulnerability. To address this, this paper offers a framework and some grounded examples contributing to the current knowledge of co-design in marketing.


The issues like fake news & privacy leaks may go against confidentiality and security considerations. AI is frequently employed in social media even as primary tool to stop the leakage of user privacy. Large quantities of data are shared over the social Internet of Things (SIoT), which are then evaluated by the other IoT devices to create, consolidate, & prepare databases for analysis. This study explored whether people on social media will release information or far safeguard privacy in response to technology intervention if faced with information privacy concerns. It looked at privacy issues' effects on information security awareness & perceived privacy control. The findings demonstrated the connection between comprehending information security awareness and customer alienation. This study examines several AI techniques and their effects on social media firms. Twitter, Instagram, Linkedin, Pinterest, & YouTube are examples of modern cultural media, commonly referred to as social media. The privacy worries of customers are positively impacted by AI and SLOT technologies. Users can really lessen their concerns about data leaks via privacy protection. This study revealed that the frequency of user knowledge transfer is influenced by user confidence in the platform. The sector has to put more effort into maintaining user privacy & creating a comprehensive security mechanism.


Current status of environmental protection performance of food soft packaging in our country was introduced.Environmental protection performance of food soft packaging was discussed from the aspects of printing mode,material,printing process,and equipment.The development countermeasures were put forward,which were application of environmental friendly ink,green packaging design,printing process control,and application of green packaging and printing technologies.


Stroke is sudden development in cerebral disturbance due to insufficient blood supply by either blockage (ischemic) or bleeding (hemorrhagic) of an artery in the brain. The aim of this thesis is to explore the ability of deep learning and quantitative image analysis to aid in triaging these patients. For ischemic stroke, therapy decision depends on the extent of the infarct core, which is best characterized on diffusion-weighted imaging (DWI), while CT is the commonly available imaging modality in emergency radiology. A deep learning system has been developed that is able to predict the extent of DWI infarct core from 3-phase CT data. Predicted infarct core lesion volumes led to low incorrect therapy decision rates, implying potential clinical usability. For hemorrhagic stroke, likelihood of hematoma expansion is an important factor in therapy selection. The recently proposed I2-score prediction model for hematoma expansion, based on quantitative dual-energy CT (DECT) angiography iodine features, has been modified to a model combining DECT iodine features with quantitative unenhanced CT texture features. Feature selection and ranking showed that DECT iodine features perform better than NCCT texture features, and that a combined iodine-texture model was not able to outperform the I2-score.