This paper presents the design of a novel wideband bandpass frequency selective surface (FSS), which is comprised of sandwiched arrays of cascaded back-to-back patch resonators with a C-type slotted ground in-between. Three transmission poles are generated to realize the desired wideband frequency responses, with a 3-dB fractional bandwidth of 85% and an insertion loss of 0.27 dB at the center frequency of the passband when the incidence is normal. The out-of-band rejection bandwidth is shown to range from 14.5 GHz to 22.8GHz for the presented design, though it is scalable.


The objective of this study was to propose a facile method to manipulate the molecular weight and practical mass production of chitosan by mechanical shearing and concurrent ultrafiltration (UF) treatment. The proposed method was based on the degradation rate and rate constant of various process variables, such as: solution temperature, reaction time, concentration of chitosan solution, with or without concurrent removal of degraded fragments during mechanical shearing. The result obtained was that the degradation rate constant was 1.8–6.0 times higher for those using UF to remove smaller degraded molecules concurrently during treatment, than that without UF treatment. The degradation rate constant increased with increasing solution temperature; however, the solution temperature should not exceed than 50°C to prevent the undesired color changes of the resulting product. A method combining mechanical shearing/UF treatment at 50°C and ultrasonic radiation or microfluidization/UF treatment at 30°C is proposed here for a facile method to manipulate the molecular weight of the resultant chitosan with an energy saving, efficient and practical mass production. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010


Soybean milk and celery juice were mixed and then fermented by Str. thermophilus and L. bulgaricus. Through orthogonal experiments, the optimum formula was determined as follows: celery juice 8%, Str. thermophilus and L. bulgaricus (1∶1) 4%, sugar 7%, stabilizer 0 30%. Celery and soybean yoghurt with nice flavour and mouth feel was obtained after fermentation at 43℃ for 4~5 h.


The Catatumbo from a geostrategic and geopolitical perspective plays a key role in the Colombian conflict, armed actors and the abandonment of the state make a dent in the internal conflict, the situation of the peace process requires society and Universiades to raise not only the problem but the solution to what is evidence.


The value of vicinal coupling constants extracted from NMR spectra in deducing torsion angles for conformational analysis is well recognized. Due to the abundance of protons, their couplings have been mostly widely used. In many instances, couplings between protons and other nuclei may be a valuable complement to proton-proton couplings or, in some instances, may be the only coupling available to characterize the torsion angle about a bond. Recently, heteronuclear couplings have been used to great benefit in studies of isotopically enriched proteins, and this general approach has been extended to peptides at natural abundance. The possibility of using this approach to study oligonucleotides is also attractive but has not as yet been widely exploited. With the development of strategies for labeling such molecules, particularly RNAs, this may become an important component in conformational analysis. For DNA, labeling is less accessible, but sufficient quantities of unlabeled material are readily available for measuring these couplings at natural abundance. We chose several DNA systems to explore the usefulness of heteronuclear couplings in addressing the sugar conformation and the glycosidic torsion angle. Intensities of cross peaks in long-range HMQC experiments can be related to the couplings. Crosspeaks involving H1{prime} and C1{prime} atoms havemore » been emphasized because of the superior shift dispersion at these positions between sugar protons and carbon atoms. Results will be shown for the self-complementary Dickerson duplex dodecamer sequence d(CGCGAATTCGCG) and for d(GGTCGG), which dimerizes to form a G-tetrad structure incorporating both syn and anti base orientations. The couplings provide a clear discrimination between presence of C3{prime}-endo and C2{prime}-endo conformations of the sugars and syn and anti bases arrangements.« less


Archaeometric methods such as provenance studies must be predicated on understanding the processes that underlie the production of this information. This study focuses on element-based provenance studies of Mississippian-period pottery, which are complicated by the fact that this pottery generally was tempered with crushed shell in different amounts and of unknown species composition. Experiments conducted at the Missouri University Research Reactor (MURR) have documented elemental dilution and enhancement effects of adding shell temper to clay. Mathematical corrections previously have been employed to correct for shell-temper effects. Results of physical, chemical, and mathematical approaches to eliminating the effects of shell tempering indicate that mathematical methods, based on a firm knowledge of shell composition, provide the most efficient correction.


Measuring the impact of digital technologies and devices – particularly the use of the internet – on children's lives through reliable statistical data is essential to the design of effective public policies to promote children's rights in the digital age and to protect them online. Policy-makers need high-quality data to underpin evidence-based policy decisions. Although it is clear that reliable statistics are needed for effective policies, and that the impact of evidencebased policies can only be measured by good statistics, most countries lack systematic and comparable statistics on the online risks and opportunities experienced by children. This Methodological Guide provides a framework for the production of high-quality, reliable statistics to measure access to and use of the internet and digital devices by children. Although this framework is aligned with the good practice of official statistics agencies, it does not replace theoretical and practical guidance or informed expertise on survey methodologies. The proposed framework provides practical guidance for activities related to administering the Global Kids Online (GKO) survey in the field, from planning to implementation.


In recent years,with the rapid development of the economy and urbanization process in China,application of excessive chemical fertilizers and pesticides and live-stock excrement excretion,the agricultural water and soil environment pollution is more and more serious,which has great restricted the sustainable development of the agricultural economy and affected food security.The status of agricultural environment pollution was analyzed,and the corresponding control measures were put forward.


Very low‐frequency, deep ocean ambient noise is generated by non‐linear interactions (collisions) between surface waves with nearly equal frequency, propagating in nearly opposite direction. It is shown that the usual "standing wave" approximation used to compute this noise predicts that the ratios of entries in the power spectral density matrix, obtained from auto and cross‐correlations of acoustic velocity and pressure fluctuations, are universal constants. This prediction is too strong and not observed. A careful consideration of bottom effects invalidates the standing wave approximation. Nevertheless a weak version of the standing wave approximation still holds and has interesting implications. While the ratios of entries in the power spectral density matrix due to surface wave generated noise are not universal constants, they are insensitive to the details of the surface wave spectrum. This theoretical prediction is borne out by data from the Hawaii‐2 Observatory. [Work supported by ONR.]


IntroductionThe telecommunication sector, especially the mobile phone sector, in India is one of the fastest growing business segments of the country which provide a lot of value addition to the society with its service and creation of employment opportunities. In the dynamic and globally changing environment every country with their effective techniques and communication becoming them more competitive. Now a days society is living with advance technology and everyone expect peace with the new technology. Mobile industry making their expansion due to huge demand and increasing customers. This increases buyers and also market size worldwide. Globalization and liberalization forces influence telecom operators to retain more customers by providing them advanced customer services only than they can ensure their market share and sustainability.Today the customer acquisition cost in cellular and mobile companies is comparatively higher than other industry so companies are seeking a new way to aquire, retain and increase their customer base. This process becomes more crucial for telecom industry due to the increased competition worldwide worldwide. This is possible only when the companies only provide quality services to the customers. It is essential that service quality of mobile phone users be examine time to time to know the weaknesses and emerging trends in the sector.Telecommunication has created much more attention in recent years for both rural and urban areas. Today at least eight telecom operators (Seven private and one Govt.) are providing the telecom services in Rajasthan, but the aggressive competition has forced the incumbent telecommunication company to re construct their strategies and business plan to sustain in the cut through competitive market. In this changing market where technology are regularly being updated by the companies it is difficult to make the long stability until and unless the services are not up to the marks and expected by the customers. Customers are not loyal to a particular company as the are receiving many options from different companies hence the major private telecom forced how to create loyal customer base. It is more essential for all telecom operators to realize the necessity of studying the customer's requirements and expectations (such as corporate image, service quality, switching cost, trust, customer satisfaction etc.) to create loyal customers. These all activities can be accomplished when we know that how the major telecom company makes their effort to establish a better customer relationship management. This should be analysed carefully that further will provide answer that which company is best in the area for which the research is going to be studied.This study specifically analyses the extent to which CRM is being practiced by the mobile service operators, and investigate the effect of the service quality of the mobile service providers on the Customer Loyalty. The objective of this study is to analyse a conceptual framework empirically that considers the interrelationships of customers perceived service quality, trust, and customer satisfaction and customer loyalty in the context of a group of customers of two major private telecommunication company(Airtel and Reliance) in Rajasthan. In this research, the quality of service provided by the mobile phone industry in Jaipur and Kota District in Rajasthan is probed.2. Litrature ReviewAccording to Berry (1983) the attraction of new customers can be viewed only as intermediate step in the marketing process. The author discussed five basic strategic elements to analyze the customer relationship management: introduce core service around which to build a customer relationship, focus on each individual customer, providing the core service with extra benefits, pricing services to motivate customer loyalty and better marketing to employees so that they can perform well to the customersThe main responsibilities of Service marketers' to build up long-term relationship with their customers by understanding the main causes of the problems faced by the customers and resolving these problems promptly to establish better relationship. …


Background: The use of sodium-glucose cotransporters type 2 (SGLT2) inhibitors is associated with reduction in cardiorenal outcomes in patients with heart failure and reduced left ventricular ejection fraction (HFrEF). Objective: To clarify the therapeutic role of SGLT2 inhibitors in patients with heart failure and mildly preserved ejection fraction (HFmpEF) and heart failure with preserved ejection fraction (HFpEF). Methods: Pubmed search until October 26, 2022. Search terms included: heart failure, SGLT2 inhibitors, hospitalization, mortality, safety. Randomized clinical trials and guidelines of major societies were reviewed. Results: 2 well-designed trials, the EMPEROR-Preserved and DELIVER trials, have shown that use of SGLT2 inhibitors was associated with decrease cardiac events in patients with HFmpEF and HFpEF. In the EMPEROR-Preserved, empagliflozin 10 mg/d decreased a composite primary outcome of cardiovascular (CV) death or hospitalization for heart failure (HHF) compared with placebo, hazard ratio (HR) 0.79 (95% CI, 0.69-0.90, P <0.001). In the Deliver trial, dapagliflozin 10 mg/d decreased the primary outcome of CV death or worsening HF, HR 0.82 (95% CI 0.73-0.92, P <0.001). The effects of empagliflozin and dapagliflozin on the primary outcome were evident and statistically significant versus placebo after 13-18 days post randomization. In both Emperor-preserved and Deliver trials, no significant effects on CV death were demonstrated. By pooling data from the 2 trials, the effects of empagliflozin and dapagliflozin on CV death was close but did not reach statistical significance, HR 0.88 (95% CI 0.77-1.00, P =0.052). Meanwhile, after pooling 2 dapagliflozin trials to include patients with HFrEF (DAPA-HF trial) and HFmpEF + HFpEF (DELIVER trial), dapagliflozin significantly decreased CV death, HR 0.86 (95% CI, 0.75-0.98, P =0.02) and all-cause mortality, HR 0.90 (95% CI, 0.82-0.99, P =0.03). The CV effects of empagliflozin and dapagliflozin were consistent regardless of age, gender, presence or absence of diabetes or atrial fibrillation. Yet, the effect of empagliflozin on decreasing HHF was attenuated in patients with baseline left ventricular ejection fraction (LVEF) of ≥60% and disappeared at LVEF ≥65%. On the other hand, dapagliflozin effects on cardiac outcomes remained consistent regardless of baseline LVEF. Both empagliflozin and dapagliflozin were generally well tolerated, with rates of drug discontinuation due to adverse effects similar to those with placebo.


Aspects of the present disclose involve a system comprising a computer-readable storage medium storing at least one program, and a method for finding experts based on case resolution logs. In example embodiments, the method may include extracting a plurality of topics from case resolution logs and using the extracted topics to model the relationship between experts and received user queries in order to identify experts with the most relevant expertise with respect to the user queries. The method may further include presenting an expert selection interface that includes a list of the identified experts and information about the experts to assist users in the expert selection decision.


The reaction of benzo-4-pyrones with dimethylsulphoxonium methylide gives three types of products, 2,3-dihydro-2,3-methanobenzo-4-pyrones (V), 2-vinylcoumaran-3-ones (VI), and 1-(2-hydroxyaryl)butane-1,4-diones (VII). The 2,3-dihydro-2,3-methanobenzo-4-pyrones (V) are readily hydrolysed to the butane-1,4-diones (VII), and this reaction may occur during the isolation of the latter products. The structural relation between these products is discussed in terms of reaction mechanism, and the effects of substituents upon product ratios are also considered.


We present a semiautonomous robotic pen-drawing system, called SSK, that is capable of creating pen art on a large nonplanar surface. Our robotic system relies on a seven-degree-of-freedom impedance-controlled manipulator with a three-degree-of-freedom holonomic mobile platform. We use a vector-graphics engine to take an artist's pen drawing as input, and we generate Bézier spline curves to be drawn on the given target drawing canvas. Then, our system finds a set of minimal, discrete configurations for the mobile platform to cover the entire canvas surface while considering the reachability of the manipulator. The drawing is split into multiple subdrawings according to the found configurations. Our system replicates the spline drawing on the target surface using impedance control, which enables us to compensate for the uncertainty and incompleteness inherent to canvas-surface representations and various robotic and sensor noises. We demonstrate that our system can create visually pleasing and complicated pen art on large, nonplanar surfaces.


The cryptographic constructions we're going to see in further lectures and courses are built on top of various algebraic structures. All these structures, however, are ultimately built on top of integers. The set of integers is Z = {. . . ,−2,−1, 0, 1, 2, . . .}. On this integers set, we are given the binary operations "+" (addition) and "·" (multiplication). The multiplication of elements can also be denoted by a simple juxtaposition of those elements, if that does not cause any confusion. The algebraic structure1 (Z,+·) is a commutative ring, meaning that


In arid and semi-arid countries, where drought prevails together with population growth and limited food resources led to the search for non-conventional alternatives resources for food or feed. In the present study, the ecology, phytochemical composition, and nutritional value of two Echinochloa species (Echinochloa colona (L.) Link and E. stagnina (Retz.) P. Beauv.) collected from the canal banks of the Nile Delta, Egypt were investigated. The soils of E. stagnina had the highest values of moisture content (24.35%), water holding capacity (45.85%), pH (8.12), electric conductivity (5 dsm-1), chloride (1.15%), sulphates (0.95%), organic carbon (2.52%) and Na+ (66.78 mgkg-1). The cover percentages of E. stagnina showed positive significant correlations with water-holding capacity, organic carbon, pH, EC, Na but negative correlations with sand-fraction and sulphates. The shoot of E. stagnina had the highest values of moisture (11.20%), fibers (27.65%), crude proteins (6.90%), total carbohydrates (70.36%), but the shoot of E. colona had the highest contents of total fats (2.80%) and digestible carbohydrates (43.18%). The shoots of E. stagnina had the highest values of flavonoids (6.88 mg g-1 dry weight), alkaloids (5.66 mg g-1 dry weight), tannins (18.23 mg g-1 dry weight), saponins (1.99 mg g-1 dry weight) and total phenols (33.09 mg g-1 dry weight). Regarding nutritional status, E. colona had the highest total digestible energy (60.55%) and nutritive value (11.11%) while E. stagnina had the highest caloric value (219.72 kcal/100 g dry matter) and potential energy (315.21 kcal/100 g dry matter). The two Echinochloa grass are rich-source in nutrients and showed a great energy value. Therefore, the studied grasses are candidates as feed for livestock or as supplementary feed but after detailed toxicological studies.


Original studies and authoritative reviews by four dozen experts from ten countries delineate the current state of biosocial research in schizophrenia. Recent developments world-wide on a broad range of issues including etiology, diagnosis, treatment and care delivery systems in schizophrenia research and management are presented, making this a resource for both researchers and clinicians in the mental health field.


A Euclidean distance matrix (EDM) is one in which the (i, j) entry specifies the squared distance between particle i and particle j. Given a partially specified symmetric matrix A with zero diagonal, the Euclidean distance matrix completion problem (EDMCP) is to determine the unspecified entries to make A an EDM. We survey three different approaches to solving the EDMCP. We advocate expressing the EDMCP as a non-convex optimization problem using the particle positions as variables and solving using a modified Newton or quasi-Newton method. To avoid local minima, we develop a randomized initialization technique that involves a nonlinear version of the classical multidimensional scaling, and a dimensionality relaxation scheme with optional weighting. Our experiments show that the method easily solves the artificial problems introduced by Moré and Wu. It also solves the 12 much more difficult protein fragment problems introduced by Hendrickson, and the six larger protein problems introduced by Grooms, Lewis and Trosset.


An electrodynamic heating mechanism is proposed to account for the precipitation of kilovolt energy electrons during an auroral disturbance. It is shown that given the existence of an electric field transverse to the geomagnetic field caused by space charges in the magnetosphere, currents will flow along the magnetic field connecting the space charges to the conducting ionosphere. It is shown that the longitudinal current deduced from magnetic observations can be of sufficient intensity to become unstable, resulting in growing ion acoustic waves. In the nonlinear limit these waves tend to inhibit current flows in a collisionless plasma and transform the ordered flow energy into turbulent energy, thus resulting in extreme electrodynamic heating of the electrons. The flow of these 'hot' electrons down the geomagnetic field lines is believed to be responsible for the bright aurora and accompanying ionospheric absorption.


Erdheim‐Chester disease (ECD) is a rare histiocytosis characterized by infiltration of multiple tissues by CD68+ foamy Mϕs (or 'histiocytes'). Clinical manifestations arise from mass‐forming lesions or from tissue and systemic inflammation. ECD histiocytes harbor oncogenic mutations along the MAPK‐kinase signaling pathway (BRAFV600E in more than half of the patients), and secrete abundant pro‐inflammatory cytokines and chemokines. Based on these features, ECD is considered an inflammatory myeloid neoplasm, and is accordingly managed with targeted kinase inhibitors or immunosuppressive and cytokine‐blocking agents. Evidence is emerging that maladaptive metabolic changes, particularly up‐regulated glycolysis, represent an additional, mutation‐driven feature of ECD histiocytes, which sustains deregulated and protracted pro‐inflammatory activation and cytokine production. Besides translational relevance to the management of ECD patients and to the development of new therapeutic approaches, recognition of ECD as a natural human model of chronic, maladaptive Mϕ activation instructs the understanding of Mϕ dysfunction in other chronic inflammatory conditions.


In this paper the key technique in independent product development of car sunroof was researched. Firstly the reversal engineering and software CATIA were applied to create the 3D model and the virtual prototype. Then the 3D model was imported into ADAMS to create the dynamical simulation model. Finally the model was parameterized and the optimization design was carried out. The research work in this paper can shorten the product development period and reduce the development cost.


Objective To develop a method of reversed phase high performance liquid chromatography( RP-HPLC) for the determination of Voriconazole concentration in mice lung. Methods With Ketoconazole as the internal standard,voriconazole was extracted from mice lung samples by protein precipitation with acetonitrile. The X-Terra Rp C18column(250 mm ×4.6 mm,5 μm) was selected to analyze the samples. The mobile phase consisted of acetonitrile-glacial acetic acid triethylamine buffer solution(41∶ 59). Flow rate was 1 mL /min at 25 ℃. The detection wave length was 255 nm.Results The standard curve was linear when voriconazole concentration in the range of 0. 14- 28 μg /g( wet lung weight). The regression equation is 0. 142 1X + 0. 025 7,r = 0. 9997. The average extraction recovery rate was 102. 58%± 5. 92%. The average analytical recovery rate was 102. 23% ± 5. 67%. The RSD of the between-day was 1. 30%- 5.41%. The RSD of the within-day was 5. 42%- 5. 68%. Conclusion The established method was accurate,sensitive and stable. It is suitable for the determination of voriconazol concentration in mice lung.


Currently, more than 50 countries have enacted or proposed regulations for mycotoxins in food and feed. There are various factors that may influence the establishment of tolerances for certain mycotoxins, such as the availability of toxicological data, the availability of data on dietary exposure, the distribution of mycotoxins over commodities, legislation of other countries with which trade contacts exist, and the availability of methods of analysis. In practice, only few countries have formally presented the rationale for the need to regulate, or for the selection of a particular maximum tolerated level, as a recent international enquiry demonstrated. Most of the limits for aflatoxins in food were based on rather vague statements of the carcinogenic risk for humans. There was a general consensus that exposure to a potential human carcinogen that could not be totally avoided should be limited to the lowest practical level. Several countries made a claim to a hazard evaluation (Belgium, Canada, India, Th...


Fifteen diploid (haploid X wild species) F1 families were generated at Huancayo, Peru in 1987. Haploid parents are adapted to long day tuberization conditions, while wild species clones were originated from short day conditions. First selection was made for tuberization under short day conditions and for tuber appearance in 517 F1 seedlings which were grown in a field at 3, 000 m above the sea level. Evaluation for 2n pollen production was conducted using acetocarmine glycerol stain, at least once at Huancayo (high land), San Ramon (subtropical), and Lima (irrigated desert) in Peru, and 60 clones were selected. These clones from First Division Restitution (FDR) 2n pollen via modified microsporogenesis. These 60 clones were evaluated for resistance to potato tuber moth, root-knot nematode, bacterial wilt and/or potato virus Y. Fifteen clones were selected from 2n pollen producing plants based on at least one resistance trait. Preliminary trials were made on 4x X 2x families using the selected diploid clones as males to determine the level of transmission of the quantitatively inherited resistances for root-knot nematode and potato tuber moth. The present work indicated that small population size at the diploid level could be used for simultaneous selection on adaptation for tuberization, 2n pollen, and resistance traits. Furthermore, it appears that selection of progeny from unadapted parents with respect to short day tuberiza-tion was effective if the selection is made on tuber forming ability rather than yield components.


Using payment systems to drive higher quality and lower costs in health care—pay for performance—has gained significant traction among policymakers and some payers. But pay-for-performance initiatives related to nursing care are just emerging, largely because while nurses are central to patient safety and quality of care, their work remains invisible to payment systems. This brief offers the perspectives of leading experts on the challenges and possibilities


Significance The p63 gene encodes a master regulator of epidermal development and function. Specific mutations in p63 are causative of a life-threatening disorder mainly characterized by severe skin erosions and cleft palate. Little is known about the mechanisms underlying disease pathology and possible treatments. Based on biochemical studies, genetic mouse models, and functional assays, we demonstrate that these mutations cause p63 protein misfolding and aggregation. Protein aggregation lead to reduced DNA binding and impaired transcriptional activity. Importantly, genetic modifications of p63 that abolish aggregation of the mutant proteins rescue its function, revealing that ankyloblepharon-ectodermal defects-cleft lip/palate syndrome is a protein aggregation disorder and opening avenues for therapeutic intervention. The p63 gene encodes a master regulator of epidermal commitment, development, and differentiation. Heterozygous mutations in the C-terminal domain of the p63 gene can cause ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome, a life-threatening disorder characterized by skin fragility and severe, long-lasting skin erosions. Despite deep knowledge of p63 functions, little is known about mechanisms underlying disease pathology and possible treatments. Here, we show that multiple AEC-associated p63 mutations, but not those causative of other diseases, lead to thermodynamic protein destabilization, misfolding, and aggregation, similar to the known p53 gain-of-function mutants found in cancer. AEC mutant proteins exhibit impaired DNA binding and transcriptional activity, leading to dominant negative effects due to coaggregation with wild-type p63 and p73. Importantly, p63 aggregation occurs also in a conditional knock-in mouse model for the disorder, in which the misfolded p63 mutant protein leads to severe epidermal defects. Variants of p63 that abolish aggregation of the mutant proteins are able to rescue p63's transcriptional function in reporter assays as well as in a human fibroblast-to-keratinocyte conversion assay. Our studies reveal that AEC syndrome is a protein aggregation disorder and opens avenues for therapeutic intervention.


Real–time concentrations of PM10 were monitored over a 24 hour period for a number of different subjects as part of an investigation to examine the influence of daily activities and locations on the personal exposure of city centre office workers to air pollution. The resulting data comprised time series plots consisting of a series of peaks and troughs as a result of exposure to the differing sources of particulate matter subjects were encountering as well as the underlying background concentration. In order to separate the background concentration component from the data a number of baseflow separation techniques were employed, commonly used in stream–flow hydrology. Filter separation and frequency analysis techniques were examined comparing their predictions of background concentration with urban background concentration measurements for reference. The results of this investigation highlight a number of different approaches to separating background concentration from real–time personal exposure data. These methods will enable further investigation of purely activity and location based personal exposures as well as improvements in the numerical modelling of air pollution exposure in future. The results of this investigation also demonstrate a novel synergy in methods of analysis between the fields of air pollution and hydrology.


This paper proposes string matching algorithm for detecting music plagiarism based on melodic similarity. Melody sequence is obtained using the harmonic structure model, and similarity between two melodies is calculated using the edit distance. The proposed algorithm includes extracting melody from the input query for generating string sequence and finding melodies in the DB that are close to the query melody as potential melodies which the query has plagiarized.


Unijunction GaAs solar cells structures were grown on buffer GaAs/GaP/Si layers. The buffer layers were different in their crystallographic orientation ((001 or 00-1)), presence or absence of dislocation filters, also number of thermocycling operations. Solar cells without a antireflection coating were fabricated, and their characteristics were measured. Some perspective directions for improving the quality of layers GaAs/Si offered based on the experimental data and analysis of literary sources.


The temperature status monitoring of power equipment is very important to ensure the safe operation of the power grid, and the fault temperature is generally in the normal temperature range. Under normal temperature conditions, the magnitude of the thermal radiation intensity in the visible waveband is small and changes slightly with temperature. Therefore, infrared detection is generally used to detect temperature. In this paper, the chromaticity information of visible images of the copper plate and aluminum plate caused by normal temperature changes is studied. First, establish image libraries of copper plate and aluminum plate at 10°C-100°C, extract the chromaticity gray values of the R, G, and B components of the images at different temperatures, and calculate the frequencies of each gray level to obtain the gray frequency distribution of each component. Then, the change law of the gray frequency distribution curve with temperature is analyzed qualitatively, and the statistical features of the gray frequency distribution of each component are calculated. Some of features are selected by the Fisher criterion. Finally, the k-Nearest Neighbor (KNN) algorithm is used for temperature recognition whose input features is a combination of the selected features. The results show that the average test error of the KNN temperature prediction model is within 1°C, which achieves a good prediction effect, and the dimension of the input feature can influence the prediction effect. The above results provide a new technical route for detecting normal temperature using visible image information.


Quantitative holographic phase contrast imaging enables high-resolution inspection of reflective surfaces and technical phase specimen as well as the minimally invasive analysis of living cells. However, a drawback of many experimental arrangements is the requirement for a separate reference wave which results in a phase stability decrease and the demand for a precise adjustment of the intensity ratio between object and reference wave. Thus, a self interference digital holographic microscopy (DHM) approach was explored which only requires a single object illumination wave. Due to the Michelson interferometer design of the proposed setup two wave fronts with an almost identical curvature are superimposed. This results in a nearly ideal pattern of spatial off-axis carrier fringes and a constant interferogram contrast in the hologram plane. Moreover, the hologram evaluation with spatial phase shifting reconstruction algorithms and Fourier transformation-based spatial filtering methods as well as the integration of DHM in common research microscopes is simplified. Furthermore, the use of laser light sources with a short coherence length is enabled. The applicability of the proposed self interference principle is illustrated by data from the analysis of technical and biological phase specimens. The obtained results demonstrate that the method prospects to be a versatile tool for quantitative phase contrast imaging.


Monetary policy is evaluated on the effectiveness an inflation containment and an unemployment control. We can say the vast majority of Central banks have chosen as the main criterion its monetary policy the inflation control. The stable price level plays a special role in achieving macroeconomic equilibrium, it allow to predict the economic situation and to shape the investment climate, which led to the expansion an inflation targeting. The choice of monetary control methods depends on the object and purpose regulation, the degree of maturity of the financial system. So, constantly discusses the transmission mechanism channels and the impulses which they to create in the economy. Therefore, the necessary models to test inflation, managing the exchange rate of the national currency. The article for this purpose, the proposed model auto regression and DSGE to investigate the relationship between inflation, the exchange rates and "a replacement currency level" and the monetary aggregates volatility. The object of regulation, are macroeconomic characteristics of the lending processes. The achievement of the desired macroeconomic effect, the Central Bank provides through the use of economic levers of influence, adjusting the economic incentives of financial institutions.


Various abiotic stresses, such as drought, salinity, heat, flooding, ion toxicity and radiation are the major constraints to agricultural production. The understanding of molecular basis of plant response to these environmental conditions has been a major focus of research in the past decades. Several genes/pathways and regulatory networks involved in stress responses have been worked out employing various approaches. Quite a few of these components have been used for engineering abiotic stress tolerance in model and crop plants via classical biotechnological and/or breeding approaches. Success to generate stress-tolerant plants has been achieved to some extent, which has resulted in increased crop yield (Mickelbart et al., 2015). However, novel strategies are desirable to overcome the limitations of classical methods, such as lack of precision and requirement of substantial time to increase the crop production in the current climate change and ever increasing population scenario. The recent availability of genome editing tools provides ample opportunity to introduce targeted modifications in the genome efficiently to study the functional aspects of various components of the genome in diverse plants and offers potential avenues for production of abiotic stress-tolerant crop plants.

Genome editing tools provide a method for introducing targeted mutation, insertion/deletion (indel) and precise sequence modification using customized nucleases in a wide variety of organisms. Zinc finger nucleases (ZFNs), transcriptional activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 (CRISPR-associated nuclease 9) are the most commonly used genome editing tools (Voytas, 2013; Mahfouz et al., 2014; Kumar and Jain, 2015). In general, these sequence-specific nucleases cause double-strand breaks (DSBs) at the target genomic locus/loci, which is/are repaired by the intracellular repair pathways; nonhomologous end joining (NHEJ) or homology-directed repair (HDR). NHEJ leads to the introduction of indels and HDR can be used to introduce specific point mutations or insertion of desired sequences (such as tags or new domains) via recombination. Owing to the simplicity of programming, CRISPR-Cas9 system has opened a plethora of options for genome editing in various biological contexts. Here, we highlight the emerging applications and future avenues of CRISPR-Cas9 system to understand the biology of abiotic stress tolerance in plants.


Virtual studio takes advantage of chroma key technique to make the pictures,mainly hosts in the foreground,com-pletely integrate into the ones in the background produced by computers.With the help of the well-developed 3D technique,people in shots can be set in any scene at will.Being magical and vivid,virtual studio is being widely used,especially in campus culture reconstruction in colleges and universities.


The widening process of straight stream channels is the most fundamental and simple fluvial process in alluvial rivers, though it is hardly observed in natural rivers. Prediction of this process based on the hydraulic consideration is a first step for the elucidation of more complicated fluvial processes in alluvium which relate to extreme river disasters. In this paper, as for the straight channel widening, the movement path of the sand eroded from a side bank and the lateral sediment transport are clarified by tracer tests and changes with time of cross sectional shape in detailed experiments, and by using these results the process of cross sectional variation is simulated under longitudinally uniform condition and problems in the analysis are pointed out. In addition, the widening process under longitudinally varying conditions are dealt with by a extended one-dimensional analysis with the consideration of the initial and the boundary condtions. The applicability of this analysis proves to be high till the beginning of channel meandering mainly caused by well-developed alternating bars, though the analysis has two major points to be improved. One of these points is to find out the equation of the side bank erosion expressing the actual process including the conditions of bank collapse and effects of bed and water level variations, and the other is to give the upstream boundary conditions suitably for the case when an initial ability of sediment transport of the stream channel differs largely from the rate of sand supplying.


Risk-averse Markov Decision Processes (MDPs) have optimal policies that achieve high returns with low variability, but these MDPs are often difficult to solve. Only a few risk-averse objectives admit a dynamic programming (DP) formulation, which is the mainstay of most MDP and RL algorithms. We derive a new DP formulation for discounted risk-averse MDPs with Entropic Risk Measure (ERM) and Entropic Value at Risk (EVaR) objectives. Our DP formulation for ERM, which is possible because of our novel definition of value function with time-dependent risk levels, can approximate optimal policies in a time that is polynomial in the approximation error. We then use the ERM algorithm to optimize the EVaR objective in polynomial time using an optimized discretization scheme. Our numerical results show the viability of our formulations and algorithms in discounted MDPs.


Objective: The difficulty value and complete quality is two magic weapons to obtain victory in the gymnastics competition.The paper reviewed current situation of the development and changes of world women's floor exercise during the London Olympic Games period from the above-mentioned two perspectives,found out the main problems and gaps,and pointed out the coping strategies and recommendations of narrowing gaps.The main goal is to raise the technical level of our country's floor exercise and to have positive significance for China's preparation for the 2016 Olympic Games.Methods: The paper mainly adopts the methods of document literature,video observation,expert interview and theme analysis.Conclusions: Improving difficulty value and complete quality is the current situation in London Olympics period.Women's floor exercise has become the weakness of China,and we have fell behind with the foreign excellent athletes on six aspects such as the difficulty of group,difficulty credit,somersault movement types,quality of complete set movements and so on.The effective ways to raise the technical level of China's floor exercise are paying attention to physical fitness,improving compression ability,all-round development of somersault movement type and innovative action,improving the complete quality,cultivating personal style.


It is unclear whether improvement in patient‐reported outcomes (PROs) relative to baseline symptom burden in Crohn's disease (CD) is associated with subsequent endoscopic remission.


Objective
To evaluate the safety and efficacy of fiberoptic bronchoscopy in the diagnosis of 41 neonates with weaning failure.

Methods
A retrospective study on the results of fiberoptic bronchoscopy was performed in 41 neonates with weaning failure.

Results
A total of 41 neonates of throat abnormalities were examined by fiberoptic bronchoscopy, including 38 cases with laryngomalacia, 8 cases with serious hyperemia and swelling of the vocal cords, 2 cases with scar stenosis of subglottic, and one case in each of congenital laryngeal web, glottic insufficiency and congenital epiglottis cyst; trachea-bronchial abnormalities, including 31 cases with tracheomalacia, 2 cases with tracheal stenosis, 4 cases with partial bronchial stenosis, 1 cases with bridging bronchus and 1 cases with tracheoesophageal fistula.Thirty-eight neonates underwent fiberoptic bronchoscopy to obtain bronchoalveolar lavage fluid and culture, bacterial culture positive in 15 cases(39.4%), of which 5 cases of Klebsiella pneumoniae, 3 cases in each of Pseudomonas aeruginosa and Acinetobacter baumannii, 2 cases of Staphylococcus aureus, 1 case in each of Escherichia coli and Streptococcus mitis; fungal culture positive for 6 cases(15.7%), of which 3 cases of Aspergillus fumigatus, 1 case in each of Candida glabrata, Candida albicans and Candida parapsilosis.The most common complications of fiberoptic bronchoscopy were hypoxia and heart rate transient decline(26 cases, 63.4%), 3 cases fever after operation.

Conclusion
Fiberoptic bronchoscopy can not only find congenital tracheal deformity and tracheal mucosa lesions, but also complete the etiology from deep discharge.Fiberbronchoscopy is safe and reliable given adequate preparation and if it is performed by skilled personnel.

Key words:
Neonates; Weaning failure from mechanical ventilation; Fiberoptic bronchoscopy; Mechanical ventilation,


Sixteen-chain sequentially rotated fed antenna array on low-temperature cofired ceramic substrate is presented. A 60 GHz broadband circular polarised (CP) stacked rectangular patch antenna is implemented as an element. All the feedlines have the same length which is differentiated from conventional T-junction divider feeder. By this way, several drawbacks of conventional sequential rotated array can be overcome such as phase error occurrence, amplitude mismatch, and axial ratio bandwidth degradation. Moreover, digitally controlled by phase shifters, beamforming performance can be evaluated. The simulated and measured S
 11
 shows broad bandwidth from 57 to 66 GHz. In addition, the radiation patterns show a peak gain of 17.2 dBi and a wide coverage of ±63°.


This chapter lays out the major events and causes of the financial meltdown and recession of the 2000s. It also discusses the Federal Reserves policy response to the crisis.


This paper investigates the data transferring technologies of fluid structure interaction simulation. Based on different methods, it provides the interface data coupling idea for the numerical simulation of fluid structure interaction.


The paper comprehensively introduces research on conceptions ,constructral standards ,modes and specifications of maintanence of ruaral road in China and points to some questions , then puts forward some suggestion of it.


This paper expounds some problems existing in the application of block building,and analyzes the factors influencing the shear performance of small-sized concrete hollow block masonry.


Frog (Rana pipiens) sciatic nerve was incubated, with and without stimulation, in an oil bath. The correlation between changes in the magnitude of the compound action potential (α and β) and changes in metabolites, particularly energy reserves, during anoxia and recovery from anoxia was studied.


Background: Trigeminal neuralgia (TGN) is usually caused by arterial compression of the trigeminal nerve. There are very few cases caused by intra-axial brainstem masses. Little information is therefore available regarding the response to incomplete resection of offending lesions. We present one such case, and systematically review the published in the literature. Methods: Case report and systematic review of MEDLINE and EMBASE Results: Case report: A seven year-old girl is referred with typical TGN pain. MRI revealed a cervicomedullary tumor with no abnormalities of the pons or trigeminal nerve. Subtotal resection under neurophysiologic monitoring was achieved, leaving a small residual attached near the expected location of the trigeminal spinal nucleus and tract.Patient recovered well with resolution of her TGN pain. She is asymptomatic seven years post-operatively. Literature Review: We found no other published cases in children or secondary to gliomas. Among reviewed cases, only two underwent surgery. Both were adults with brainstem cavernomas and both reported substantial improvement despite incomplete resection. Conclusions: Our case as well as literature review both show that surgical resection is beneficial in such cases and, even if subtotal, can result in substantial pain relief. This suggests intra-axial compression of the trigeminal spinal nucleus and tract as the possible cause of TGN pain in such cases.


A system of three spin12 atoms allows the construction of a qubit in the subspace of total angular momentum j = 12 that is not a ected by any magnetic eld activity on the magnetic moments of the atoms, provided that all three atoms experience the same magnetic eld. If, however, there are stray elds of di erent direction or strength at the sites of the atoms, the qubit will slowly decohere. It is the objective of this study to examine the decoherence process and to establish the conditions, under which the lifetime of the qubit is su ciently long for practical uses.


Detailed analysis of the geometry of damage zones and seismic properties in the immediate vicinity of faults is required to aid interpretation of fluid migration pathways. This level of analysis can be greatly facilitated by combining manually guided fault slicing with 3D seismic attribute driven Fault Damage Zone geobody delineation to generate fault based attributes, Allan diagrams and throw maps that accurately reflect the underlying data.


Abstract Forest fires are abrupt transformations of the natural ecosystem and management authorities are required to take preventive measures to tackle fire events. Geographic information system (GIS) is a powerful tool for providing information with a spatial context and analytical hierarchy process (AHP) is a well-established technique for multiple criteria decision making. In this study, GIS and AHP are combined to analyse seven fire-related factors related to climate, topography and human influence. Fire risk for a peat swamp forested area in Kuan Kreng, Nakorn Sri Thammarat province, Thailand is estimated in five categories. 705 historic fire events from 2006 to 2017 are used to validate our approach. 82% of the historic fire incidents occurred within the highest fire risk class categories while only a few omission errors were recorded. The combined approach of GIS and AHP techniques can yield useful fire risk maps, which can consequently be used for future planning and management of fire prone areas.


In this paper, the natural and man made disasters of sandy coast complex at home and abroad are analysed and discussed, and the research items that shall be carried out in this field and the prevention technique are also proposed.


The Biofilm mode of growth provides such significant advantages to the members of the consortium that most organisms in important habitats are found in biofilms. The study of factors that allow manipulation of biofilm microbes in the biofilm growth state requires that reproducible biofilms by generated. The most effective monitoring of biofilm formation, succession and desquamation is with on-line monitoring of microbial biofilms with flowcell for direct observation. The biofilm growth state incorporates a second important factor, the heterogeneity in the distribution in time and space of the component members of the biofilm consortium. This heterogeneity is reflected not only in the cellular distribution but in the metabolic activity within a population of cells. Activity and cellular distribution can be mapped in four dimensions with confocal microscopy, and function can be ascertained by genetically manipulated reporter functions for specific genes or by vital stains. The methodology for understanding the microbial ecology of biofilms is now much more readily available and the capacity to manipulate biofilms is becoming an important feature of biotechnology.


The most suitable teaching strategy to implement vertical integration between basic and clinical sciences is problem-based learning (PBL). My personal experience in faculty of medicine in King Abdulaziz University where the medical curriculum used information – oriented approach. Medical student learns basic and clinical sciences, through understanding the essentials of each science separately. Since 2009, PBL was implemented through system modules for the third year students. PBL session help students to think, discuss and share their current knowledge, analyze and generate ideas to test possibilities underlying problem scenarios which represented common health problems in the community. The advantages of PBL for better joining of basic and clinical sciences which lead to improvement of the learning outcome domains where, the students declared that PBL enabled them to gain learning skills and, more satisfaction, and better outcome after graduation.2


The physico-chemical parameters and plankton diversity of Awba Reservoir, University of Ibadan was sampled from April to July, 2011. Surface water samples were collected for physico-chemical parameters. Values of the physico-chemical parameters observed ranged as follows: water temperature, 24-26.5°C; air temperature, 22-23. °C; transparency, 0.2-0.4 m; pH, 7.3-8.4; total dissolved solids, 143.8-159.5 mg/L; conductivity, 290.8-391.5 µmhos/cm; salinity, 0.11-0.19%; dissolved oxygen, 0.7-1.8 mg/L and alkalinity, 0.8-1.7 mg CaCO3/L. Thirty six taxa of plankton were encountered. Phytoplankton consisted of five families namely; Cyanophyceae, Chlorophyceae, Euglenophyceae, Bacillariophyceae and Dinophyceae. Three groups of zooplankton encountered were copepods, cladocerans and rotifers. The presence of pollution indicator species such as, Microcystis, Phacus, Oscillatoria, Surirella Closterium, Aphanocapsa, Anabeana and Euglena show that the Reservoir is likely polluted.


The study examines the level of climate change vulnerability on the inhabitants of Yenagoa, and determine the adaptation strategies in the area. Temperature and rainfall data were obtained from the archive of Global Precipitation Climatological Centre (GPCC) and Nigeria Meteorological Agency Satellite for Yenagoa for 62 years (1958 to 2019. Also, 400 copies of questionnaire were administered. The result showed high level vulnerability of climate change that has precipitated sea level rise, flooding, rise in temperature. Thus, leading to decline in farmland, food insecurity, headers farmers' crisis, reduction in forest resources, growth and development of crops and increase in pest and diseases. It has also impacted the educational system negatively such as disruption in the educational system, closure of schools, lateness to school, relocation of students, destruction of bridges, and road accident and irregular traffic flows. Other are low patronage in recreation and tourism, low turnout for outdoor games, and destruction of tourism facilities. Others a rereduction in income, high cost of living, reduction in gross domestic product (GDP). The study therefore posited climate insurance, promotion of alternatives farming practices, carbon sequestration, green city green roof approach amongst others as the adaptation strategies


While treatment of 1,3,5-triazine NC(H)NC(H)NCH 1 with a [LiCH2R]6, b [LiCHR2]∞ or c [LiSiR3(thf)3] (R = SiMe3) was believed to yield the 1,4-adducts LiNC(H)NC(H)(R′)NCH 2a–c, by contrast, 1 with [LiNR2]3 or [Li(thf)4][Li(CR3)2] under similar conditions gave the 1,3,5,7-tetraazaheptatrienyllithium [Li3{RNC(H)NC(H)NC(H)NR}3] 4 or 1,3,5-triazaheptatrienyllithium [Li2{RNC(H)NC(H)NC(H)CR2}2(µ-thf)] 5 compounds, implicating a trimethylsilyl-shift and subsequent ring-scission. For 2b, the transformation to the 1,3,5-triazaheptatrienyllithium compound [Li4{RNC(H)NC(H)NC(H)C(H)R}4] 7 was accomplished by heating the solid to 140 °C. Although compound 4 was unreactive towards tmen or pmdien, from the triazaheptatrienyllithium compound 5 and pmdien, the lithium compound [Li{RNC(H)NC(H)NC(H)CR2}(pmdien)] 6 was isolated. The tri- 4, di- 5, tetra- 7 and mono-nuclear 6 lithium compounds have been fully characterised, including their X-ray crystal structures.


The contagion of the new coronavirus pneumonia (COVID-19) not only seriously endangers the safety of human, but also affects the development of the national economy There are few reports on factors influencing the transmission of 2019-nCoV, such as environmental conditions (humidity and temperature), air pollution, and human activities It is difficult to sample and research 2019-nCoV directly Therefore, it is significant to investigate the factors influencing the spread and survival of other similar viruses, which is instructional for the prevention of epidemics and the control of 2019-nCoV transmission The results show that: (1) Low temperature and low humidity could prolong the lifetime and increase the transmission of coronavirus, especially on dry surfaces For example, coronavirus can survive on a smooth surface at a temperature of 22-25 ℃ and a relative humidity (RH) of 40%-45% for more than 5 days (2) Similarly, the survival rates of the aerosolized coronavirus is also high in a closed environment at low temperature and low humidity, 2019-nCoV may hold high survival rates at a temperature of 20-25 ℃ and a relative humidity of 30%-50% (3) The higher the particle concentration, the risk of 2019-nCoV transmission may increase (4) The behavior of infected people also plays a important role in the transmission of 2019-nCoV The transmission of virus can be reduced by avoiding sneezing and coughing in the crowd, and blocking the transmission of droplets using hands, elbows or other objects Considering the above analysis, some suggestions for the prevention and control the epidemics are made, such as improving the indoor microenvironment, investigating the detection, inactivation, influence factors and propagation characteristics of 2019-nCoV © 2020, Editorial Board, Research of Environmental Sciences All right reserved


In the teenage years we observe a new form of libidinal object relationship, based on the sameness quest throught elective friendship, peers'group and so on. This idea of the imaginary twin, based on narcissistic homosexual cathexis is used as an original defensive process against loneliness, loss of the incestuous object idea, and links attack by agressive rivalry. It constitutes a pattern, free of oedipus representatives, proceeding as a protective shield between the body image and intrusions of the external reality, and traumatic breakings from the libidinal puberty pressure. The double, internal and external, deffered mirror stage amends the primary identification in a new ideal relation to the sexed body, defining new marks to the adolescent identity process. Resting on the works of freud, lacan and bion, we shall try to define the inscription of this concept in the psychoanalytic narcissism theory. We shall then analyse through clinical cases and from p. Aulagnier's throught, the return of a "new archaic" (omnipotence of the thinking, disawoval, splitting) in the psychopathology of the adolescent (breakdown, psychosis). We shall finally evaluate the impact of this fantasy in the psychotherapy of adolescent disorders, through group-therapy and taking into consideration the body and its acting out, this "familiar stranger" who affraids the adolescent himself.


This paper seeks to provide a measure of the quantum change required in the quality of initiatives which the University must take to deal with the pattern of financing which appears to be required in the light of the evolving economic circumstances which confront contributing member Governments of The University of the West Indies and the new priorities which they have to address.


Case Age at Cause of No. Onset Sex Ophthalmoplegia Manifestation (yrs) 1 47 F S u b a r a c h no i d !Fuchs's phenomenon of lid retraction on adduction haemorrhage Pseudo-Graefe phenomenon of lid retraction on looking down 2 i F Typhoid Paradoxical retraction on occlusion of sound eye 3 5 M Head injury Lid retraction on attempted adduction Pseudo-Graefe phenomenon of lid retraction on looking down Paradoxical retraction on occlusion of sound eye 4 56 M Syphilis Lid retraction on attempted adduction 5 Birth F Congenital Lid retraction on occlusion of sound eye 6 Birth F Congenital Duane's retraction syndrome 7 52 M Myasthenia gravis Prostigmine-positive lid retraction (uncommon type) 8 Birth F Congenital Lid retraction on attempted adduction and on occlusion of sound eye 9 Birth F Congenital Marcus Gunn phenomenon (even clenching the teeth on the right side with'closed mouth caused retraction)


Cyclodextrin glucanotransferase (CGTases) catalyze the degradation of starch and maltodextrin to form cyclodextrins (CDs). CDs have various applications in food industry, cosmetic, pharmaceutical, toiletries, agrochemical industries and analytical chemistry. Overexpression of recombinant CGTase in intracellular E. coli expression system faces several problems especially the low expression level of recombinant CGTase and the formation of inclusion bodies. Low expression level is mainly due to the toxicity of accumulated recombinant protein that was expressed in the cytoplasm of E. coli, finally caused the cell death. Secretory E. coli overexpression system provides a promising solution to overcome this problem. The objective of this research is to overexpress the recombinant CGTase extracellularly in E. coli expression system. Preliminary studies show that co-expressing both CGTase and bacteriocin release protein (BRP) genes able to obtain the extracellular recombinant CGTase. The CGTase gene was amplified using polymerase chain reaction (PCR) method. The purified PCR fragment was cloned into pWH 1520 shuttle vector and transformed into E. coli that harbouring pJL3-BRP gene. The CGTase gene is regulated by xylA promoter and is induced by xylose; meanwhile the BRP gene is regulated by lac promoter and is induced by IPTG. The secretion pathway involves the permeabilization of the cell envelope that was activated by BRP and the release of bacteriocin molecules is accompanied by the release of the recombinant CGTase. The expression of extracellular recombinant CGTase at 37°C achieved 34.17 U/ml after 24 hours induction, with 0.5 mM xylose and 40I¼M IPTG as inducers.


Heterosis over better parent (BP) for seed yield and yield components in linseed was studied using line × tester analysis involving ten genetically diverse strains used as lines and four testers. The heterosis over better parent for seed yield plant-1 ranged from 48.69 to 552.85 %. Five crosses consistently exhibited significant positive heterobeltiosis for higher seed yield plant-1, viz., RLC-132 × RLC-92, R-4154 × Indira Alsi-32, R-4158 × Deepika, R-4129 × Kartika and RLC-132 × Kartika indicating that these crosses might be useful in linseed hybrid production. These crosses also had significant and positive heterosis for days to 50% flowering, number of capsules plant-1 and oil content and would be more desirable to exploit heterosis in linseed.

https://www.ijcmas.com/7-11-2018/Namrata Dhirhi, et al.pdf


In 1939 the Dutch artist Rueter sent out a questionnaire to his colleagues asking for instructions on the maintenance of contemporary paintings. Since then, a range of interdisciplinary and collaborative projects for the conservation of contemporary art followed in the Netherlands. This article discusses the growing importance of documenting the artist's intent and the role of museum staff as performer in the execution and conservation of the works.


A novel main circuit topology of three phase PFC AC/DC converter is proposed in this paper. Its operation process and power factor correction principle are discussed and analyzed in detail. Finally, its simulation and experiment results are given.


In this paper, a novel feature extraction method called TQWT-CSP based on sliding time window is proposed, which can extract the spatial features of multiple time-frequency blocks, so as to select different optimal feature sets for different individuals before motor imagery classification is completed. Firstly, the linear discriminant criterion is used to select channels of the signal after preprocessing; Secondly, the signal is decomposed and reconstructed into multiple subbands by using TQWT, and each subband is divided into 11 time periods which are overlap by using the sliding time window, so as to get several time-frequency blocks; Next, the CSP algorithm is used to obtain the feature set; Finally, the random forest feature selection algorithm is used to select the optimal feature subset and support vector machine is used for classification. In the experiment, 10 subjects in the of GigaDB Motor Dataset are used to verify the performance of the proposed method. The average accuracy, kappa coefficient, sensitivity and specificity using 5-fold cross validation were 82.14%, 64.11%, 80.60% and 83.71% respectively. The results of experiment show that the proposed method improve the classification performance and is at a high level among the numerical measurement indicators given in the state-of- the-art research literature.


Object of this study is the Kingma family in Makkum in the province of Friesland. Seven generations of this family are reviewed. Our central question is: how did the individuals of these generations - consciously and unconsciously - construe the familial identity. ... Zie: Summary


Make payment and transfer funds anywhere using your mobile phone. FEATURES: - View current balances of your accounts - Transfer funds between your accounts - Transfer funds to other PAY|ALL users and registered/unregistered E-Money/Nationlink Card Holders...


Excerpt The marked decrease in the mortality of pulmonary tuberculosis is undoubtedly due to many causes. It is not, many hold, a true measure of the decrease of the morbidity of the disease. Pulmo...


Some properties of Regge trajectories for interatomic potentials of the Lennard-Jones type are considered. An exact differential equation for the trajectories is derived. An approximation similar to the rigid rotator and neglect of centrifugal distortion approximation allows this equation to be integrated and predicts a linear relation between Re (λ n 2) and the energy E. A semiclassical analysis complements the formal analysis and gives a physical interpretation to the integration constant Re Cn as well as to Im λ n : Re C n is related to the vibrational states of the potential and Im λ n is related to the angle of rotation of the atoms about each other. A numerical example is presented for a Lennard-Jones (6, 4) potential, with parameters approximating low energy H+-Ar elastic scattering.


The invention provides a preparation method of a thermal insulation coating high-performance polyurethane elastomer. After the reaction of terminal hydroxyl polybutadiene liquid rubber and polyisocyanate, polyurethane is added for reaction for 3 to 4.5 hours at 85 to 90 DEG C to produce isocyanate-terminated prepolymer; a certain amount of heat insulating filler is added in the prepolymer and is mixed evenly to produce component A; chain extender, antioxidant, curing agent and solvent are mixed evenly according to a certain portion to produce component B; the component A and the component B with the weight portion of 3: 1 to 6: 1 are mixed, stirred evenly, cured at room temperature to produce the thermal insulation coating high-performance polyurethane elastomer. The process of the invention used to synthesize the thermal insulation coating high-performance polyurethane elastomer is more reasonable, the product has higher quality and better comprehensive properties. The test date shows that the tensile strength is 3.50 to 5.80MPa, the elongation at break is more than 220 percent, the bond strength is more than 10.0MPa, the glass transition temperature is less than 60 DEG C below zero, the solidification shrinkage rate is less than 0.1 percent. The product is mainly applicable to aerospace industry.


Methods 42 women between 24 to 34 weeks of gestation underwent an ultrasound growth scan followed by a computerized cardiotocograph (CTG). Post-capture analysis of the actograph recording was performed and expressed as a percentage of activity over time. The actograph output results were analysed in relation to estimated fetal weight (Hadlock) based on ultrasound and expressed as z score normalized for gestation.


According to the 2016 results, in Russia migration growth is likely to return from lower rates to the level of the past few years. As before, migration virtually ensures completely population growth in Russia. The two largest metropolitan areas (Moscow together with the Moscow Region and St. Petersburg together with the Leningrad Region) and the Krasnodar Territory are the main centers which attract migrants. Also, there is a renewal of growth in temporary foreign migration (season migrants) in a summer period. The number of season foreign migrants is below the level of 2013–2014 and even that of 2015. In 2016, the issues related to regulation of labor migration have become more topical: the number of work permits required for employment keeps falling.


A new charter to tackle the 'bloody mess' of community health services will be launched next year, RCN President Professor June Clark has announced.


Environmental valuation is the process of expressing a value for a particular good or service in a context of
decision making usually in terms of money or numbers. It's also considered to be a measure or indices of social, biological,
ecological and demographic status of the system. Marine and coastal ecosystems provide a wide range of services include
the provisioning services, regulating services, cultural services and supporting services. Food provisioning in the form of
fisheries catch, aquaculture, ornamentals and bio prospecting is the most vital services from this system. The Total
Economic Value of (TEV) consists of use values and non-use values. The use value includes direct use value, indirect use
value, and option value, whereas the non-use value is the existence and bequest value. Three approaches are used in the
valuation techniques: Slated preference (contingent valuation and choice modelling); Revealed preference (market price,
cost-based, production, travel cost); Benefit transfer. The overexploitation of resources, degradation of the ecosystem will
directly affect the food security and employment of the coastal population and have an indirect effect on the regional and
national economy. To address these issues, environmental valuation is considered to be one of the effective tools for the
Scientists and Managers. The green accounting refers to efforts to modify the national income accounts from which GDP
and GNP are calculated, to incorporate use and depletion of natural resources. Stocktaking and dimension are the backbone
of green and social accounting. The Global Reporting Initiatives (GRI) and International Organization for Standardization
(ISO 14000) are the two frameworks developed for social and green accounting. The green accounting has applications in
large scale and small scale business organizations. Development and implementation of green accounting will be a
challenging issue for the companies coming in the years ahead. It is an interdisciplinary framework includes several
magnitudes and divisions of environmental accounting. It needs a sound environmental policy, environmental accounts and
their recording and training of the future practitioners to provide technical and legal basis of green auditing. The Kyoto
protocol of the Convention on Biological Diversity (CBD) is a legal binding agreement with the developing countries and
developed nations designed to reduce six greenhouse gases that are believed to contribute to global warming. The Kyoto
Protocol is an environmental accounting in action on an international scale


In this paper, manufacturing issues include Optical Sub-Assembly (OSA), Electrical Sub-Assembly (ESA) andreliability considerations of 10Gb/s Ethernet transponder were studied by using experiments and implementation.In the growing optical communication industry, one of the star products is the Z-axis pluggable optical transceivermodule. Under the broad usage of Ethernet means high port density, low cost, high utilities, compact size and stillrequire excellent performance. After standardizing of 10Gb/s ethernet (IEEE 802.3ae), many transceiver companies,silicon vendors and system vendors reached the agreement and signed up diversity ofMSA (Multi-Source Agreement).These MSAs still keep modifying with system demands, customer requirements, cost and performance issue. This paperpresents how to achieve these functions description in the MSA and own a highly manufacturability and reliabilitymodule design. According to composed block of transponder, we split it in to OSA, ESA, mechanical design and relatedreliability experimental result.In the OSA, traditional TO-CAN package and optical components be introduced [1-3]. Because the maturemanufacture experience, vendor can easy to meet low cost and manufacturability requirements and only need to slightlymodifications. A simply solution be implemented to solve this problem and discuss the critical point ofthe design.Thermal issue on OSA will also be mentioned because of the sensitive of light source and how to calculate the effect tofind effective solutions. By the way, some manufacturability criteria will be discussed for OSA characteristics in 10Gb/sapplications. In the ESA, PMD (Physical media dependant) driving methods, Multi-Source Agreement related digitaloptical monitor function implement and performance comparison will be presented. On the other hand, we will examinethe crosstalk effect between transmitter and receiver circuit and impact to the module Optical to Electrical convertinterface design. We still need to take well-assembly between OSA and ESA into consideration. Perfect assembly willlead us to earn wonderful reliability and manufacturability. In the mechanical design, many reliability andmanufacturability issue need to consider such as thermal, EMI, temperature, humidity effect etc. So, module mechanicaldesign must be highly collocation with ESA, OSA, heat spreader and special EMI shielding design. Experimental dataand thermal simulation result are also prepared to guide us forward to a successful product.Keywords: Transponder, Optical Sub-Assembly (OSA), Electrical Sub-Assembly (ESA), ElectroMagnetic Interference


Article history: Received 25 Feb 2010 Received in revised form June, 5, 2011 Accepted 7 July 2011 Available online 9 July 2011 This research aims to present how choosing a suitable layout can improve the performance of virtual cellular manufacturing systems (VCMSs), especially minimizing the material flow between machines required by each family group. To present the efficacy of basic layouts on performances of VCMSs, a multi-objective mathematical model with a goal programming (GP) approach is developed to generate VCMSs based on resource-elements (REs). The formulated model is coded in Lingo software and is run over functional and distributed arrangements of the same machines. The performance and the validity of the developed model are checked by a numerical example taken from the literature. The objective function of the mathematical model is measured for that example over two mentioned layout to compare the performance of the generated systems. Moreover, because of the material handling costs importance, material flows are measured to find the best option as a basic layout for VCMSs. To compare the performance of the generated system with the classical cellular manufacturing system (CMS), cell capacity utilization (CCU) is employed as an independent criterion to evaluate each system. The result illustrates the priority of distributed layouts for generating RE-based VCMSs because of its flexibility, minimizing the objective function for the mathematical model, and smaller material flow by the components. In addition, the generated VCMSs outperforms the classical CMS from the CCU point of view. © 2012 Growing Science Ltd. All rights reserved


The scriptures include many references to creative women. Hannah and Dorcas created treasured textiles (1 Samuel 2:19; Acts 9:39), but we don't know what those garments looked like. Sarah created memorable meals for her guests (Genesis 18:6), but we don't know her recipes. The daughters of the Lamanites danced in delight (Mosiah 20:1), but no technology could capture their creative whirl. So most of the results of women's creative efforts have been lost to history. But one form of women's ingenuity has survived: contained within the canon itself are several examples of women's sacred songs. This paper will explore some of these songs; we'll see that sacred songs have been a central venue for women's theological activity. We begin with Miriam. After crossing the Red Sea, Miriam the prophet1 took a small drum, danced, and sang: "Sing2 ye to the Lord, for he hath triumphed gloriously; the horse and his rider hath he thrown into the sea" (Exodus 15:21). That's not a long song.3 But it is enormously significant. The story of the Exodus begins with Miriam's actions beside the waters that hold her helpless baby brother,4 and the story ends with Miriam again beside the waters, this time celebrating Moses' victory over the waters. Rescue from the waters and the centrality of Miriam's words are


Background The most commonly used treatment for neonatal hyperbilirubinemia (NH) are phototherapy and exchange transfusion. Among the drug therapy for NH less has been paid to the effect of zinc administration on serum bilirubin level (SBL). This study was carried out to determine the on the effect of oral zinc sulfate on the SBL in term neonates with hyperbilirubinemia. Materials and Methods In this randomized clinical trial, we studied term neonate with jaundice hospitalized in Amirkola Children's Hospital, Babol-Iran for phototherapy. Eligible neonates were randomly divided into two; intervention (n=30) and control (n=30) groups. Both groups received standard conventional phototherapy but the intervention group received 5 mg per day oral zinc sulfate until discharge. The outcome variables were SBL and the duration of phototherapy. Results Out of the 105 studied neonates, 50 cases were in the intervention group and 55 patients were in the control group. The mean SBL before intervention in the intervention and control groups, was 17.4 ±2.1 and 17.1±2.2 mg/dl, respectively (P>0.05) but after the intervention, it decreased to 8.8±0.77 and 8.7±0.99 in intervention and control groups respectively (P>0.05). The mean differences in the decrease in SBL between the two groups were 8.8 and 8.3 in intervention and control groups respectively (P>0.05). But the mean duration of phototherapy in the intervention group and the control group was 4.1 days and 3.6 days respectively (P<0.05). Conclusion Administration of oral zinc in neonatal hyperbilirubinemia under the phototherapy could decrease the duration of phototherapy. Further studies are needed to recommend it as an adjunctive therapy to phototherapy.


Research Purposes Aims to determine how much influence accountability, integrity, auditor expertise, auditor professional skepticism, due professional care, time budget pressure, and audit fees have on audit quality. Research Methods All auditors who work at the Public Accounting Firm (KAP) Semarang Central Java are the population of this study. A total of 13 public accounting firms with 64 auditors became the research sample. With the help of SPSS version 26, multiple linear regression analysis was performed on the data. Research Results and Findings, The results of hypothesis testing show that integrity, auditor professional skepticism, due professional care, and time budget pressure do not affect audit quality. Meanwhile, accountability, auditor expertise, and audit fees have a positive effect on audit quality.


Abstract : Since 1967, military pay has been linked or indexed to changes in General Schedule (GS) salaries via the professional, administrative, technical, and clerical (PATC) index. This effort compares the PATC index to other wage indexes using a set of criteria. They include the similarity of jobs in the military to those in the wage indexes, the timeliness and quality of data contained in the indexes, and the ability of the indexes to maintain real purchasing power. Several existing wage indexes, predominately blue collar, were found to be more appropriate guides for adjusting pay than the PATC index. (Author)


We consider here the moduli space M of stable principal G-bundles over a compact Riemann surface C, with G an algebraic complex group. We denote by K the canonical bundle over C. In [Hi] N.Hitchin defined an analytic map H from the cotangent bundle T ∗M to the "characteristic space" K by associating to each G-bundle P and section s ∈ H(C, adP ⊗K) the spectral invariants of s. Hitchin showed for G = Gl(n), SO(n), Sp(n) that the generic fibre of H is an open set in an abelian variety A. In fact, he considers in each case a non-singular spectral curve S covering C: when G = Gl(n), A is identified with the Jacobian J(S) ; in the other cases, there is a naturally defined involution on S and A is the associated Prym variety. More recently, Faltings extended these results and described an abelianization procedure for the moduli space of Higgs G-bundles, with G any reductive group (see [F] ). If T ⊂G is a fixed maximal torus with Weyl group W , one may construct for each given generic element φ ∈ K a ramified covering C̃ of C having |W | sheets. The combined action of W on C̃ and on the group of one parameter subgroups of T induces an action on the space of all principal T -bundles τ over C̃ and we may consider the subvariety P̂ of those τ which are W invariant in this sense. The connected component P0 of P̂ which contains


The aims of the present study were to synthesize magnetite nanoparticles mediated by the extract of velvet bean (Mucuna pruriens) seed from Indonesia and evaluate its anticataleptic effect on haloperidol-induced catalepsy mice. The magnetite-M. pruriens seed extract nanoparticles (FeMPn) were synthesized by reacting ferric chloride (FeCl3) solution with M. pruriens seed extract. Scanning Electron Microscopy-Energy Dispersive X-ray (SEM-EDX), Transmission Electron Microscopy (TEM), Fourier-Transform Infrared (FTIR) and Thermogravimetric Analysis/Differential Thermal Analysis (TGA/DTA) were used to characterize the FeMPn synthesized. Catalepsy test of FeMPn was performed at dosages of 5, 10, 15, 20 and 25 mg/kg body weight. SEM and TEM images showed the aggregation of FeMPn with a spherical shape and smallest size of 30.5 nm. FTIR spectra confirmed the presence of Fe-O bonding from the absorption band at 557.4 cm. TGA/DTA results confirmed that the addition of Fe leads to increase the thermal stability of the extract. The administration of FeMPn at all dosages was able to lower the catalepsy in mice significantly and it was better than the extract itself with the best dosage was 10 mg/kg body weight. These findings suggest that FeMPn could be a promising option for antiparkinson treatment.


A convenient strategy for identifying the motion errors from the tilting-rotary table of 4-axis simultaneous control machine tools with a ball-bar is proposed,including the axial testing and cone-shaped testing.In the axial testing the double-circle motion,in which two translational axes and one rotary axis are simultaneously controlled to keep the distance between the tool and the worktable constant,is designed to identify the deviations of the rotary axis,thus two angular deviations and one positional deviation are obtained,and the other two positional deviations are obtained by the cone-shaped testing.To achieve high-precision measurement results,the errors due to the circular motion of the two translational axes in the double-circle motion are removed by an additional test with corresponding arithmetic.The comparative results show that the strategy greatly simplifies the measurement device and accelerates the error quantification.


Research on sediment flux from river to the sea is a frontier topic in Earth science worldwide. This paper analyzes the characteristics of annual sediment flux from Yellow River to the sea from 1950 to 2007, and presents a feasible approach to predict annual sediment flux. Methods used in this research include wavelet analysis and neural network. The results show that: (1) annual sediment flux variations from Yellow River to the sea have decline tendencies with an average decreasing rate of −20.09 million t/a between 1950 and 2007, and four catastrophe points detected are 1959, 1969, 1985 and 1997; (2) annual sediment flux series has the principal periods of 3–4 years, 8–11 years and 24 years, and the period of 3–4 years was influenced by human activities significantly; (3) prediction of annual sediment flux with the help of wavelet neural network (WNN) model is acceptable, which gives a better result than RBFN (Radial Basis Function Network) model.


This study aims to determine the effect of job insecurity, work stress and work environment on turnover intention. The object of this research is employees of the company of supplier security system in Indonesia. The sampling technique used in this study is the sample saturated with the total sample population of 82 respondents and the data analysis used is the statistical analysis of multiple linear regression tests. The results showed that the variable job insecurity had a positive and significant effect on turnover intention, work stress had a positive and significant effect on turnover intention, and the work environment had a positive and significant effect on turnover intention.


Introduction: We have previously reported that sudden cardiac death in middle-aged subjects is more likely to occur without warning, and patients have fewer co-morbidities compared to older subjects. Since mechanisms may differ between the two groups, there is a significant need to perform detailed comparisons of cardiac structural abnormalities. Methods: From an established, dedicated cardiac pathology database in the Eastern US, we compared 175 consecutive middle-aged SCD patients (35-59 years) to 175 older patients (>60 years; 2005-2010). Individual level, detailed clinical and autopsy data including cardiac and coronary gross and histopathology findings were compared. Results: In both groups, there was a male majority (middle age 75.4% and older 72.6%; p=0.54). There were no significant differences in cardiovascular risk factors such as hypertension, diabetes mellitus and hyperlipidemia. The prevalence of significant coronary artery disease (CAD, >75% stenosis in any major coronary artery) in the absence of acute coronary thrombosis was lower in middle age (30.9% vs. 42.9%; p=0.02) and middle aged cases were also less likely to have chronic total occlusion (CTO) (18.9% vs. 32%, p Conclusions: In this detailed contemporary postmortem cardiac pathology evaluation, we observed a significantly lower burden of CAD in the middle aged vs. older groups, and a large subset of middle aged patients did not have identifiable cardiac etiologies of SCD. These findings highlight the possibility of potentially distinct mechanisms of fatal ventricular arrhythmias in middle vs. older age.


The Lime and Hemp Concrete is a building material with a low in-service thermal conductivity, and a low environmental impact over its whole life cycle. This study presents the effect of bio-based aggregates such as Hemp Shiv on elastic modulus of lime composite. Theoretical and numerical approaches are compared with experimental results. The matrix consists of a hardened lime paste. Volume fractions of Hemp Shiv range from 0 to 35%. The elastic modulus are determined by compression tests: the axial and circumferential elongations are measured using a device specifically designed for these materials. In 3D, the numerical finite element simulations predict the mechanical behavior of a matrix with spherical inclusions arranged in several configurations (periodic or random). The last part of the study provides some theoretical solutions derived from the classical homogenization methods (Mori-Tanaka, self-consistent and Hashin-Shtrikman). The consistency of the results validates the application of these theories in case of the Lime and Hemp Concrete.


ABSTRACT There are three major mathematical problems in digital terrain analysis: (1) interpolation of digital elevation models (DEMs); (2) DEM generalization and denoising; and (3) computation of morphometric variables through calculating partial derivatives of elevation. Traditionally, these three problems are solved separately by means of procedures implemented in different methods and algorithms. In this article, we present a universal spectral analytical method based on high-order orthogonal expansions using the Chebyshev polynomials of the first kind with the subsequent Fejér summation. The method is intended for the processing of regularly spaced DEMs within a single framework including DEM global approximation, denoising, generalization, as well as calculating the partial derivatives of elevation and local morphometric variables. The method is exemplified by a portion of the Great Rift Valley and central Kenyan highlands. A DEM of this territory (the matrix 480 × 481 with a grid spacing of 30″) was extracted from the global DEM SRTM30_PLUS. We evaluated various sets of expansion coefficients (up to 7000) to approximate and reconstruct DEMs with and without the Fejér summation. Digital models of horizontal and vertical curvatures were computed using the first and second partial derivatives of elevation derived from the reconstructed DEMs. To evaluate the approximation accuracy, digital models of residuals (differences between the reconstructed DEMs and the initial one) were calculated. The test results demonstrated that the method is characterized by a good performance (i.e., a distinct monotonic convergence of the approximation) and a high speed of data processing. The method can become an effective alternative to common techniques of DEM processing.


The study investigated Gender and information needs, sources, problems faced in the use of agricultural information by Cooperative Farmers in Ukwuani Local Government Area of Delta State. The study examined the information needs, information sources and also to ascertain the problems that militate against cooperative farmers while using agricultural information. To guide the study, three research questions were raised. Descriptive survey design was adopted and questionnaire was the research instrument that was used in obtaining data. The population of the study is 218 cooperative farmers (both male and female) in Ukwuani Local Government Area of Delta State. The study revealed that. Both sexes agreed that they need agricultural information on pests and disease control; improve method of farming, how to obtain credit /loan facilities and where to store and sell their produce. Result also shows that both sexes agreed that personal experience, Neighbours / Friends, and Cooperative society are some of their major sources of agricultural information. The major problems faced by both sexes of cooperative farmers in the use of agricultural information are erratic power supply, untimely information, lack of visitation by agricultural extension officer, no nearby library, lack of computer knowledge and access to agricultural databases and lack of agricultural information in my native. Based on the findings, the following recommendation was made: Government, information officers, agricultural extension workers and other relevant bodies should ensure that cooperative and other rural farmers are provided with accurate and timely agricultural information. The study concludes that agricultural information is of utmost important to cooperative farmers of both sexesin order to increase productivity.


In design of large range extensometer whose range is 100% strain, according to theory formulas and factual technics, using MATLAB to optimize the structure and size. The available method of fixing of extensometer can't eliminate eccentricity of load. The type of fastening would produce additional moment which has bad effects on linearity, repeatability and large range measurement. In this paper, the authors give improvements on the type of fastening also.


Introduction Growth failure is well-recognised in paediatric IBD (PIBD; <18 years). Evidence (usually case series from single/multiple centres) shows anti-TNF therapies improve linear growth. We aimed to examine if anti-TNF therapy improves growth in a PIBD population-based cohort. Methods Retrospective review of all children receiving anti-TNF (infliximab (IFX) and adalimumab (ADA)) from 2000–2012 in paediatric services in Scotland. Height (Ht), weight and Tanner stage were collected at 3 times: 12 months before anti-TNF (T-12), start of anti-TNF (T0) and 12 (T+12) months after anti-TNF. Ht and growth were converted into standard deviation scores (SDS) and height velocity (HV, cm/ year) were calculated. Results 97/201 PIBD cases (3ADA, 94 IFX) had 12 month growth data, 58 (59%) males and 90 (93%) Crohn's disease (CD); 84 (87%) received immunomodulators and 47 (48%) corticosteroids at T0. Median age at diagnosis was 10.3 years. In IFX treated, mean Ht SDS T-12 was -0.67 +/-1.1; improvement was then seen from T0 -0.82 +/-1.1 to T+12 -0.74 +/-1.1 (p = 0.031). Mean ΔHtSDS improved from -0.16 +/-0.38 at T0 to 0.08 +/- 0.36 at T+12 (p < 0.001) with HV improving from 3.9 cm/yr +/-2.5 at T0 to 5.0 cm/yr +/-2.9 (p = 0.003). 56 (60%) entered remission, HtSDS improved from -0.77 +/- 1.1 at T0 to -0.56 (+/-1.1) at T+12 (p = 0.0004). ΔHtSDS improved from T0 -0.14 (+/-0.04) to 0.21 (+/-0.04) at T+12 (p < 0.001) and HV from 4.0 cm/yr (+/-2.3) at T0 to 5.6cm/yr (+/-2.9) at T12 (p = 0.003). 44/94 IFX (48%) were Tanner stage 1–3; 40 CD. Mean HtSDS decreased from -1.0 (+/- 1.1) at T-12 to -1.2 (+/-1.3) at T+12 but, HV 3.6 cm/yr (+/-2.1) at T0 improved to 5.5cm/yr (+/-2.7) at T12 (p < 0.001). In Tanner 4and5, no change in HtSDS or ΔHtSDS was seen. 61 (65%) had disease for ≥2 years at start of IFX, HtSDS improved from -0.77+/-1.2 at T0 to -0.65+/-1.2 at T+12 (p = 0.007) whilst disease <2 years (n = 33) had no change; HtSDS -0.93+/- 0.97 at T0 and -0.92+/-0.89 at T+12 (p = 0.89). Improvement was seen in height velocity in ≥ 2; years HV 4.1+/-2.5 at T0 and 5.0+/-2.9 at T+12 (p = 0.039) compared to HV <2 years 3.6+/-2.3 at T0 and 4.8+/-3.0 at T+12 (p = 0.08). Greater improvement in ΔHtSDS in ≥2 yrs; ΔHtSDS at T0 -0.12+/-0.35 improved to 0.12+/-0.33 at T+12 (p < 0.001) vs. -0.22+/-0.43 at T0 to 0.16+/-0.4 (p = 0.018) for <2 yrs. In UC (n = 7) no change was seen in ΔHtSDS or HV at T-12, T0 or T+12 (p 0 >0.05). Conclusion Improvements in HtSDS and height velocity at 12 months were seen in the whole cohort. In Tanner 1–3 improvement was only seen in HV after 12 months with no improvement in Ht sSDS. No improvement in height noted in UC. Further follow up will determine if growth improvement is maintained or further improves. Disclosure of Interest None Declared.


As Internet is open,dynamic and difficult to control,the values of network contextual parameters and their changes show uncertain characteristics,which impacts importantly the execution and management of software systems on Internet.Based on the analysis of practical Internet application requirements,this paper proposes a new complex network context assessment scheme,by making use of the advantages of cloud model in transformation between qualitative concepts and quantitative values.It profiles the features of multi-dimensional network context factors,and achieves the quantitative mapping between the multi-dimensional contextual parameters and the assessment of run-time network environment.By adding the user tolerant error into calculation to adjust the number of samples dynamically,more stable and accurate assessment results can be obtained.The scheme achieves the modeling results at both parameter-level and group-level,which brings a better overall evaluation of the network status as well as helps to improve the correctness and efficiency of dynamical software reconfiguration.The effect of the scheme has been verified through a series of simulation experiments.


Book review, Jeet Heer and Kent Worcester, eds. A comics studies reader. Oxford: University Press of Mississippi, 2009. $25.00 (380p) ISBN 978-1-60473-1-088.


The study of any scientific problem involves the analysis and comprehension of the results of scientific activity of previous generations of scientists. Despite the fact that in domestic legal science the limits of legal regulation as a significant scientific problem have not received comprehensive coverage, the pages of various legal publications have expressed provisions that are of conceptual importance and serve as the foundation for its further research. The purpose of the study: to comprehend the results of the study of the limits of legal regulation in domestic legal science, highlighting the key ideas and provisions that contribute to the further study of the scientific problem posed. Research methods: general scientific methods and techniques of cognition (analysis, synthesis, induction, deduction, abstraction, generalization, comparison) and particular scientific (formal-legal, structural-functional). Results: the study of the limits of legal regulation in domestic legal science made it possible to form a serious foundation for its further study. The main results include: comprehension of the basic concepts of «the scope of legal regulation» and «limits of legal regulation»; the emergence of different approaches to the problem of establishing criteria for the limits of legal regulation; formation of a classification of the limits of legal regulation; designation of the main directions in understanding the factors of establishing the limits of legal regulation.