The erythropoietin(EPO) is a novel family of angiogenic factors that promote angiogenesis,anti-apoptosis and anti-hypoxia when binding its receptor(EPOR).The EPO participates in the development of placenta vessels,as well as the angiogenesis and tumor metastasis.EPO and its receptor expressed at reside maternal-fetal interface.Since EPO and its receptor are expressed throughout human gestation,it may play a pivotal role in pregnancy,and their abnormal regulation may be involved in spontaneous abortion,eclampsia and fetal growth restriction.Therefore,EPO in pregnancy may present a novel strategy for treatment of the pregnancy-related diseases.


The physiological effect of drought on the 30-days-old Triticumaestivum plants was assessed and the alleviating role of seaweed extracts (Sargassumlatifolium, Ulvalactucaandtheir mixture) on drought stress was evaluated. Drought treatment (40% and 20% field capacity) resulted in a significant decrease in some growth criteria, photosynthetic pigments and activity. Furthermore, it led to oxidative stress and increased cell membrane leakage in the stressed wheat plants and resulted in the increase of antioxidant (enzymatic and non-enzymatic) defense mechanism. Pretreatment with seaweed extract of Sargassum (1.5%) or Ulva (1%) led to the alleviation of the above mentioned damaging effects of drought on Triticumaestivumduringvegetative stage while a mix of the two types of seaweed extracts resulted in antagonistic effect. Seaweed extractof Sargassumor Ulva antagonizes the oxidative damaging effects of drought not only directly through activating the antioxidative system, such as catalase, peroxidase and ascorbate, but also through providing hormones and micro nutrients essential for wheat growth. * Corresponding Author: Wedad A. Kasim  email@example.com International Journal of Agronomy and Agricultural Research (IJAAR) ISSN: 2223-7054 (Print) 2225-3610 (Online) http://www.innspub.net Vol. 7, No. 2, p. 173-189, 2015 International Journal of Agronomy and Agricultural Research (IJAAR) ISSN: 2223-7054 (Print) 2225-3610 (Online) http://www.innspub.net Vol. 5, No. 1, p. 14-22, 2014


The dissolution studies on 260mg Ibuprofen tablets used deionized water to make all the solutions. 1000mL pH of 5.5 buffered solutions were prepared with sodium acetate trihydrate (3.61grams) with acetic acid (3.0mL). A 6.8 pH solution was prepared with potassium phosphate (250mL) and 0.2N sodium hydroxide (112mL). Acetic acid was used to achieve a1.2 pH medium. Timed sample intervals were pulled from the dissolution apparatus and responses were achieved through UV-visible absorbance measurements. The UV-visible absorbance wavelength for Ibuprofen was measured at 0.445 absorbance units (au). The UV-visible spectrophotometer used was Lambda 35 UV WinLab V6.0 with variable (0.5, 1.0, 2.0 and 4.0nm) bandwidths with wavelength ranges from 190 to 1100nm having scanning speeds of up to 2880nm/min with quartz coated optics. Moisture vapor sorption was measured using Perkin Elmer's Thermal Gravimetric Analyzer (SGA) to test the moisture barrier properties. Taste masking tests were done using a dissolution apparatus with 5.5 and 6.8 pH solutions to mimic the salvia pH over a one minute period with samples analyzed using a UV-visible spectrophotometer. Results Results showed passing enteric properties under accelerated stability including successful taste masking properties of a bitter active, and sealing property effects in both acidic and basic media. The results show that shellac at 0.5 to 1% weight gain provides protection against moisture sorption. Conclusion The analytical responses demonstrated Protect EN as a functional shellac coating providing enteric, sealing, moisture barrier, and taste-masking properties. This is an Encore Presentation from Excipientfest 2013 on April 30, 2013.


When traders choose their payment system, they should consider the following matters of international trading: an exporter's credit risk in collecting payments, an importer's risk of non-acquisition of contracted goods or the possibility of obtaining disqualified goods, all the necessary travel expenses, the traders' burden of keeping and managing contracted goods, foreign currency acquisition, establishment of an appropriate base for the payment system, and finally the economic complexity and reliability along with access to the payment system. The TradeCard system is an integrated electronic payment system to cope with the internet and cyber trading age. Its excellent system makes it possible to deal with business procedure electronically as well as simply and promptly, and provides various payment services such as AAP/BAP with/without protection and IP. Furthermore, it carries the advantages of L/C and collection systems through the payment guarantee by Coface and the check engine function about the document identification. In this paper, I will look into the possibility of the TradeCard system's settlement and applications in the future international trade, and suggest some methods to increase its utilization. In order to rate its possible applications, I come up with some factors about the payment system traders choose in the course of concluding international transactions, and then analyze the mechanism of the TradeCard system.


Advances in digital imaging and faster networking resources enabled an unprecedent popularization of digital video applications, not only for entertainment, but also for health and education. However, capturing, digitizing, storing and displaying video in real time remains a challenge for nowadays technology. Furthermore, the large number of frames that compose a digital video, each of them occupying hundreds of kilobytes, stress significantly both storage and networking resources available currently. A common strategy to reduce the amount of data that has to be handled while providing digital video services is compression, as specified by the MPEG coding standards, for instance. The compression cost then becomes the greatest, demanding the use of either specialized hardware or parallel computing to meet the real time demands. In this work, we propose a novel shared-memory parallel algorithm for MPEG-1 video encoding based on the modularization of dierent coarse grained tasks and the exploitation of the maximum parallelism among them. Dierent types of video sequences are used as a benchmark and rates of 43 frames per second are achieved for standard sequences with a non dedicated Sun multiprocessor with 32 CPUs.


Although this guide grows out of and is targeted to juvenile justice practitioners, it is generally applicable to programs in other social service fields as well. It also bears noting that the steps described here are neither simple nor easy. Nevertheless, they are worth undertaking even if a program does not complete the entire process, any progress along the way is likely to be beneficial.


There is not enough articles in the theory of finance related to the valuation of privately held companies since most of them are focused on publicly traded models. This was the motivation of the study, which focuses on calculating the valuation of Caixa Econômica Federal and the value of its shares DOI: 10.25110/receu.v21i2.8020 1Universidade Estadual do Oeste do Paraná UNIOESTE. email@example.com 2UNIOESTE/PR Campus Cascavel. firstname.lastname@example.com


C. utilis yeast is widely used in industry for the production of fodder protein, amino acids, vitamins, and enzymes. We have studied the antimicrobial activity of C. utilis CY 302 against such collection strains as E. coli 3912/41, S. flexneri 1a 8516, S. enterica serovar Typhimurium 79, S. epidermidis ATCC 14990, S. aureus ATCC 25923, Proteus vulgaris HX 19 222, L. casei subsp. Rhamnosus ATCC 7469, B. breve ATCC 15701, C. albicans ATCC 10231 by using the agar blocks method and by measuring the inhibition growth zone (IGZ, mm) accompanied by the target cells death zone. The yeast strain was grown on Sabouraud's medium at 28±1 °C for 3 days, and the test cultures were grown on differential diagnostic media for each bacterial species (HiMedia Laboratories Pvt. Ltd, India) at 35±2 °C overnight. The analyses were done separately for each culture. A weak antimicrobial effect was observed with respect to L. casei and B. breve, the IGZ was 5.0 and 4.0 mm, respectively. The halos of inhibition against pathogenic bacteria were 7 mm for E. coli, 5 mm for S. typhimurium, 5 mm for P. vulgaris, 6 mm for S. fiexneri, 6 mm for S. aureus, and 5 mm for S. epidermidis. After incubation there was noted the absence of DZZR in the wild C. utilis CY 302 strain in relation to the C. albicans ATCC 10231 strain from the collection. As a result of the studies the antagonistic potential of the yeast isolate C. utilis CY 302 was revealed. The work was supported by the Ministry of Science and Higher Education of Russia.


This paper explores the effective use and practical potential of open government data visualizations by media, political parties, associations and NGOs. Furthermore, it analyses the main barriers to the use of open government data by these user groups. The paper summarizes the state of research and broadens the current perspective based on empirical data from Switzerland. Finally, the paper suggests actions in order to foster the use of OGD and improve the capabilities of these user groups.


The objective of this study was to determine the presence of Escherichia coli O157:H7 in ground beef sold in the markets of Guayaquil. The method applied was descriptive, observation and non- experimental design. 200 samples were analyzed. All of then enriched with peptone water and then using violet red bile lactose agar. Colonies identified as E. coli were further identified as E. coli O157:H7. Results obtained were compared with the Ecuadorian INEM Standard 1338:2012 and showed that ground beef sold in the market of Guayaquil has poor microbiology quality with potential risk health


This work investigates secondary electron yield (SEY) mitigation from a metal surface with a microporous array fabricated using the laser drilling technique. We propose a general empirical model to fit the experimentally measured SEY of a flat gold surface for normal and oblique incidences of primary electrons. Using this empirical model, we develop a two-dimensional Monte Carlo (MC) simulation scheme to determine the effective SEY of a microporous array. It is found that the SEY from a porous surface is significantly reduced compared to that of the flat surface. By taking into account all the generations of secondary electrons inside a well, our MC results are found to be in very good agreement with the experimental data. The dependence of the SEY on the aspect ratio of the micropores and porosity of the surface is examined. A simple empirical formula has been proposed to evaluate the effective SEY of the gold microporous array for pores of arbitrary aspect ratios.This work investigates secondary electron yield (SEY) mitigation from a metal surface with a microporous array fabricated using the laser drilling technique. We propose a general empirical model to fit the experimentally measured SEY of a flat gold surface for normal and oblique incidences of primary electrons. Using this empirical model, we develop a two-dimensional Monte Carlo (MC) simulation scheme to determine the effective SEY of a microporous array. It is found that the SEY from a porous surface is significantly reduced compared to that of the flat surface. By taking into account all the generations of secondary electrons inside a well, our MC results are found to be in very good agreement with the experimental data. The dependence of the SEY on the aspect ratio of the micropores and porosity of the surface is examined. A simple empirical formula has been proposed to evaluate the effective SEY of the ...


Objective: This study is a descriptive research study aimed to identify the needs of self-reinforcement education by applying IPA(Important-Performance-Analysis) techniques to develop the health care empowerment programs for the elderly with hypertension. Methods: The subjects of this study were 128 elderly people with hypertension over 65 years of age in areas A and B, and data were collected from 6 researchers and research assistants from May 11 to June 26, 2020. The collected data were analyzed by frequency analysis, descriptive statistics, and t-test. Results: Although the question with the highest education demands were 'I try to get my health care providers to my preferences for my treatment.' and with the greatest difference between importance and performance is the question 'I take my commitment to my treatment seriously'. Conclusion: From the results of this study, it is considered that a strategy that reflects the components of educational needs and healthcare empowerment is necessary when developing healthcare empowerment programs for the elderly with hypertension.


In order to solve the problem of the spindle sealing in the Ore-dressing Plant of Baotou Steel,this thesis introduces a kind of advanced sealing way-mechanical seal.It indicates the structure and working principle of mechanical seal,and analyses the reasons of mechanical seal failures in detail,puts forward some technical problems needing attention in the installation and use of mechanical seal.


The utility model discloses an adjustable silicon damping electromagnetic magnet mechanical paw, which comprises a mechanical arm support, wherein at least one mechanical arm is arranged on the mechanical arm support; at least one electromagnet is slidably connected onto the mechanical arm; an elastic supporting piece is arranged between the mechanical arm and the electromagnet; the electromagnets are positioned on the mechanical arm through a fixing device. Compared with the prior art, the adjustable silicon damping electromagnetic magnet mechanical paw has the beneficial effects that all electromagnets can be in full contact with the surfaces of workpieces, and the mechanical arms can stably attract the workpieces under the electromagnets; in addition, the working time of the whole system is saved, and the working efficiency is improved.


When Mary V. Dearborn's unauthorized biography of Norman Mailer appeared in 1999, its subject didn't read it—in fact, had refused the author's request for an interview. Norman Mailer did, however, read its review in the New York Times of December 19 by Caleb Crain, entitled "Stormin' Norman: How a Nice Jewish Boy from Brooklyn Grew Up to Be a You-Know-Who." Crain lacerated Mailer rather than Dearborn's biography, which he said appreciated the challenge of tackling "the man and his life [as] equal" in stature. The reviewer then proceeded to enumerate Mailer's notorious public acts and reduce his literary themes to "American male animism," an unholy trinity first presented in The Naked and the Dead (1948) as the homosexual (General Cummings), the reformer (Lieutenant Hearn), and the psychopath (Sergeant Croft). The main point of the review (and perhaps the biography) was that following his first book, Mailer detonated his literary life, essentially turning those efforts into a life full of (quoting from the 1959 Advertisements for Myself) "the violent and the orgiastic." In a writing career, at least up to The Executioner's Song (1979), the man became larger and more notable than his work. When Mailer responded to the review the next day, he didn't bother to reject the main points of Crain's description of him. Rather, he took offense only to three rather minor points that were evidently in Dearborn's book— namely, that 1) he'd been a Marxist without reading Marx; 2) that he had abandoned Buzz Farber, a longtime friend who had been imprisoned for selling illegal drugs; and 3) that he had shared his Provincetown home with the notorious Roy Cohn. "Put everything in," Mailer told his authorized biographer J. Michael Lennon, author of Norman Mailer: A Double Life (2013) and now editor of the Selected Letters, and that's practically what Professor Lennon did in both cases. With the letters, however, he had to choose from over 45,000, the number much higher (twenty to twenty-five million words) than that for any other American writer because in 1958 Mailer stopped typing his own letters and started dictating them to a string of literary secretaries. The letters in the edition run from 1940 when Mailer was a student at Harvard to 2007, shortly


We present a case of novel coronavirus disease‐2019 that underwent combination therapy with nivolumab and ipilimumab for metastatic renal cell carcinoma.


The methanolic leaf extract of Triclisia subcordata obtained by macerating dried and pulverized leaves in 50 percent methanol f a 48 hour produced relaxant effects in the rabbit jejunum and rat fundus (stomach), but produced contractile effects in the rat uterus. The effective concentration (ECso 0.07 mg/ml) of the extract in the rat jejunum was determined from a plot of the percent relaxation of the tissue against the log concentration of the extract. No observable effects in the guinea pig ileum were produced by the extract. Effects of extract on jejunum, rat fundus, and uterus were antagonized by histamine. The effects of the extract appeared to be mediated through H2receptor blocking activity.


Accurate control of molten metal levels during pyrometallurgical smelting operations is critical to improve process decision-making and maximizing production efficiency, such as when to commence tapping and the duration of the tapping operation. In addition, molten metal level control is important for long-term structural integrity of the furnace. Current methods to measure molten metal levels have limited accuracy and are intermittent, as they require manual measurement from above the furnace. In this paper, a continuous measurement system was designed to improve the molten metal level measurement in pyrometallurgical furnaces. This paper describes the tests of an electromagnetic sensing system consisting of eddy current drive and pickup coils that could be embedded in the wall of a furnace. As part of the development, portions of the system were simulated using COMSOL, and a prototype of the key hardware components was built and tested in the laboratory to validate the simulation results. Differential coil hookup provided a low-noise and high-resolution response. The system obtained a molten metal level detection resolution of 5 mm at liftoff distances approximately 300 mm from the simulated metal bath. Projection to latent structures (or partial least square) and regression analyses were applied to signal response to predict metal height, and a good agreement between predicted and measured laboratory metal heights was obtained. Initial results of the prototype system demonstrate its potential to accurately and continuously measure molten metal level, thereby improving safety and control of furnace operations.


This paper deals with the integration of a reduced thermal model based on tree dimensional Finite Element (FE) thermal simulation into circuit simulator for accurate prediction of electrothermal behavior of power devices. The reduced thermal model based on the Ritz vectors approach is easily usable in any kind of circuit simulator because it is described by a spice format subcircuit. The model has been successfully experimented with the ADS simulator. Electrical based thermal measurements of transient temperature response have successfully validated our approach.


Purpose: Phase I clinical trials are the gateway to effective new cancer treatments. Many physicians have difficulty when discussing Phase I clinical trials. Research demonstrates evidence of suboptimal communication. Little is known about communication strategies used by oncologists when recruiting patients for Phase I trials. We analyzed audio recorded Phase I consultations to identify oncologists' communication strategies.


The article presents a discussion of the challenges faced by the Technical Entrepreneurial Vocational Education and Training (TEVET) system in Malawi as it attempts to provide quality technical education. The study involved 40 instructors, 8 principals, 3 TEVET center managers, the TEVETA1 head of Training, and the Directorate from the Ministry of Education Science and Technology. The findings show lack of clarity on and differences between the objective of Competence Based Education and Training (CBET) as viewed by TEVETA and that viewed by training providers instructors and students. Furthermore findings show that CBET widens the already existing disconnection being what the student achieves at the end of technical education and the employer's expectation. This paper argues that TEVETA should prioritise the desired purpose of broadening access and implementation of CBET, address training providers and learners attitude towards new approaches, and empower training providers with necessary resources and human capacity to effectively achieve the quality technical education and CBET envisioned by the TEVET of the system.

 Key words: Access, equity, quality, CBET, quantity, competence.


At present, scholars have increasingly recognized a high-quality, professional management team it's very important for the development of university, but to the problem that how to promote the professionalization of university management team, creative solutions still lack. This paper points out that the establishment of university administrators' competency model is an effective way to promote the professionalization of university management, and outlines the quality characteristics of university administrators' from the two aspects of general competencies and core competencies. Therefore, it can provide valuable reference for our selection, recruitment and evaluation for college management staff.


A sodium-sulfur battery belongs to each of a plurality of operation units. The operation units are a unit of connecting and releasing the sodium-sulfur battery to and from a power system in a parallel fashion. A first power consuming body and a second power consuming body are electrically connected to the power system. The first power consuming body belongs to each of the operation units, but the second power consuming body does not belong to the operation units. One of the first and second power consuming bodies may be omitted. Ranks are assigned to the respective operation units. The ranks become higher as the state of charge of the sodium-sulfur battery belonging to the operation units increases. When a stand-alone operation is started, a single operation unit with the highest rank is selected and the sodium-sulfur battery that is operated and belongs to the operation units is paralleled in to the power system.


AbstractThe conventional practice of calculating consolidation settlement in one-dimensional conditions involves dividing soft ground into multiple layers to enable an accurate estimation. However, the effect of layering on consolidation settlement has not been clearly verified. The authors propose an analytical solution to the case where the ground is divided infinitely for normally consolidated soils. The effect of error caused by layering in conventional practice is presented as well. Based on the suggested analytical solution, it is found that the conventional settlement calculation method always underestimates consolidation settlement. In addition, a representative depth for the conventional method in which the soft ground is not divided is suggested for calculating the same consolidation settlement as that obtained by the analytical solution.


This journalistic research work is based on analyzing the current situation of sexual harassment of women in Ecuador, the regulations that have been issued on this issue by the State and social actors. Through this work, will be evidenced in a main way the types of sexual harassment that occur in the country, and the flaws in the victim protection system. Interviews were carried out with members of the assembly, members of the public defender office and victim unit, councilor, women victims of sexual harassment in different spaces (public and private), and activists for women rights. The investigation also has figures of violence in the country, places where a woman can make a complaint in the provinces with the highest rate of violence, etc. This journalistic work was also based on making sexual harassment visible as one of the first signs of sexual aggression against women, and if it is not prevented in time it can lead to another type of violence to femicide.


Social housing providers confront an array of risks strategically and operationally. Recently, models of hybrid organisations have been developed to understand how non-profit landlords are changing in response to market and other external pressures. In this paper, we draw on a multidisciplinary conceptual framework of external and internal risks, multiple stakeholders and resilience strategies, as well as the notion of hybridity, in order to make sense of change in Scotland's social housing sector. The paper draws on elite interviews as well as case studies that seek to capture the range of approaches adopted by providers. Although providers handle and respond to risk in a variety of ways, risk management is a necessary part of the management of social housing businesses. Increasingly, providers are concerned with questions of resilience – the need to make themselves as organisations more resilient and also to promote greater resilience amongst tenants as a way of mitigating risk. Our research suggests that this is leading to some positive outcomes e.g. greater diversity within the sector and increased customer focus but there is concern that government policies remain within silos and are insufficiently flexible to deal with changed circumstances and the evolving needs and aspirations of the sector.


4034 Background: Gastric cancer is the third leading cause of cancer related death worldwide. Although targeted and immune therapy have brought new benefit for patients, it still faces challenges of limited effective group and survival. Here we investigate the association of overall survival with DNA and RNA alterations to explore potential biomarkers of prognosis in gastric cancer. Methods: Whole-exome sequencing, RNA sequencing and clinical data of 442 patients with stomach cancer were downloaded from TCGA. Clinical factors and mutational landscape (insertion/ deletion/ single nucleotide variant) were compared between group of OS3+ (overall survival > 3 years) and OS3- (OS < 3 years). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed based on differentially expressed RNAs between the two groups. Results: 415 of 442 patients with stage information were included. The corresponding rates of OS3+ for patients in stage of I/II/III/IV was 15.5% (9/58), 10.8% (9/58), 10.9% (9/58), 13.6% (9/58), respectively. When comparing the 49 patients with OS3+ to others with OS3-, no difference of stage or sex distribution was discovered, except that OS3+ group had lower median age at diagnosis than OS3- group (63 vs. 71 years, P = 0.029). Tumor mutation burden was comparable between groups. Mutational landscape showed that the two groups shared 70% of top 20 mutations. Among the 20 hot genes, mutations of ANK3(P = 0.006), PKHD1(P = 0.008) were more frequent in OS3+ group, Studies in breast and prostate cancer inferred that, ANK3 was involved in activity of androgen receptor signaling and cyclins, increased expression of ANK3 in cancer was probably associated with better survival. PKHD1 was involved in calcium ion binding and actin binding and was identified as a protective factor for colorectal cancer. OS3- group tend to have higher mutation frequency of HMCN1(P = 0.062). Previous reports showed that mutation of HMCN1 was enriched in peritoneal metastasis of gastric cancer, it might contribute to progression in gastric cancer. Enrichment analysis revealed difference between the two groups in olfactory transduction ( P < 0.01, KEGG analysis), neuroactive ligand-receptor interaction ( P < 0.05, KEGG analysis) and detection of chemical stimulus in sensory perception of smell ( P < 0.01, GO analysis). Numbers of discussions have inferred that genes involved in olfactory transduction may also participate in tumor cell proliferation, migration, and invasion. Conclusions: Patients with OS3+ was enriched with mutations of ANK3 and PKHD1 and present significant functional difference in olfactory transduction. These are potential biomarkers of better survival in gastric cancer. Further studies are needed to figure out their roles in tumor activity and provide insight for novel antitumor treatment development.


As we know a power nap during the lunchtime break helps improve work efficiency. It is also known that vibration induced environments -such as in a moving car-enhances sleepiness. And, as office work prevails in the workforce, the authors have focused on adapting a standard office chair by sandwiching between the seat and the user a thin cushion-size mechanism oscillating up and down for inducing sleep. This device is constructed based on wedge mechanism that includes a counter-weight function. Although its compactness, this device can lift a user up to 100 kg. Adjusting to the user's preferences, the rocking motion can be tuned while respecting a maximum stroke of 5mm at a peak frequency of 2 Hz.


methods used for promoting mental health. Again, the areas of disagreement are more apparent than the areas of agreement. Those who believe in the validity of their own definitions of mental health and their own theories of mental health education, and who do not wish to threaten their security by questioning these opinions, should leave this book alone. I, for one, found it most rewarding reading. It was reassuring to find that my own unanswered questions are not solely the result of my personal limitations but are questions that have not yet been answered by anyone to the satisfaction of others in the field. It was stimulating to discover that some ideas that I had felt were sound were challenged, and that some valid arguments both pro and con need further exploration. Finally, despite the present confusion, this report challenges everyone in the field to continue to work toward the goal of improved mental health. As a result of careful study, evaluation, and documentation, we shall be able eventually to establish some criteria that will provide a working (if not a Websterian) definition of mental health. We shall also have at our command, not one, but several approaches to mental health education which will have proved to be valid. Thus this report, in essence a review of the present status of the broad field of mental health, should serve to prevent undue optimism, undue pessimism, or the premature abandonment of current concepts.


The purpose of this review is to describe and discuss the diagnostic and treatment challenges related to tooth fractures primarily in the vertical plane, that is, the long axis of the crown and/or root. This includes when and how to identify and determine the extent of the fracture, when a coronal restoration should be placed, when root canal treatment is needed, and when a tooth or root should be extracted based on the location and extent of the fracture. The term 'longitudinal fractures' is used because they usually represent vertical extensions of fractures over distance and time. These fractures often present problems with diagnosis and treatment, but should be considered as findings only. They are not to be considered as pulpal or periapical diagnoses, but as pathways for bacteria that may induce pulpal and/or periapical inflammation or disease. Longitudinal fractures are divided into five definitive classifications, generally from least to most severe: (1) craze lines; (2) fractured cusp; (3) cracked tooth; (4) split tooth; and (5) vertical root fracture. These differ but have frequently been confused or combined in clinical articles, creating misunderstanding and resulting in incorrect diagnosis and inappropriate treatment. These classifications have been devised to provide global definitions that researchers and clinicians can use to eliminate this confusion. This review is subdivided into these five classifications as to incidence, pathogenesis, clinical features, etiologies, diagnosis, treatment, prognosis, and prevention.


The invention relates to a transmission, in particular a double clutch transmission, for a motor vehicle, comprising at least two sub-transmissions, wherein each sub-transmission has at least one input shaft, and an output shaft is arranged as a pinion shaft of both sub-transmissions, wherein the at least one input shaft is arranged on an input shaft axis, and the pinion shaft is arranged on the input shaft axis or on a counter shaft axis, in particular a counter shaft axis that is parallel to the input shaft axis, wherein an intermediate gear is arranged with at least one counter shaft, said at least one counter shaft being arranged on the counter shaft axis, and wherein at least four shifting elements are arranged, at least each at least two shifting elements are arranged on the input shaft axis and counter shaft axis, wherein at least one of the input shafts can be connected to the pinion shaft by means of at least two wheel planes and/or at least one shifting element, and wherein at least two, in particular at least three, preferably at least half of the at least four shifting elements are formed in a non-synchronised manner, and at least two, in particular at least a third of the at least four shifting elements are formed in a synchronised manner. The invention also relates to a method for operating a transmission, and to a method for operating a double clutch transmission.


This research aims to find the form of inventions in Popular Islamic Literature in Indonesia since 2004 until 2015. Subjects of this study are the novel Ayat-Ayat Cinta (2004) by Habiburrahman El Shirazy, the novel Hafalan Shalat Delisa (2005) by Tere Liye, novel 99 Cahaya di Langit Eropa (2011) by Hanum Salsabiela Rais and Rangga Almahendra, and the novel Surga yang Tak Dirindukan (2015) by Asma Nadia. The theory used is the Formula is the theory of John G. Cawelti. This research used qualitative methods The results showed that the formula of Islamic literature was popular in Indonesia from 2004 to 2015 experienced invention in terms of themes, characters, settings, lines, and cultural influences. The theme experienced a form starting from blessed polygamy, natural disasters, travel, and polygamy based on lies. The setting of all places in Indonesia and the country that has the Muslim majority, namely Egypt then penetrated European countries where the Muslim population actually became a minority. The original plot tended to close-ended, but in the novel Surga yang Tak Dirindukan, the open ending plot was revealed. A culture that occurs in society also influences the stories presented in the novel.


In light of Chief Justice Roberts"s tie-breaking vote to uphold the Patient Protection and Affordable Care Act (ACA) as a legitimate exercise of Congress"s taxing power, it is worth asking whether the arguments of liberal textualists played any role in shaping the historic decision. After all, an amicus brief filed by Jack Balkin and other constitutional law scholars had argued that the mandate is clearly authorized by Congress"s authority under Article I, section 8 of the Constitution "[t]o lay and collect Taxes, Duties, Imposts and Excises, to pay the Debts and provide for the common Defence and general Welfare of the United States." Did Balkin"s brief help persuade Chief Justice Roberts to uphold the Act? Although the brief may have helped, it is hard to imagine that it played a decisive role. Balkin and other liberal textualist scholars had also argued that that the Framers of the Constitution intended Congress to be able to regulate interstate commerce to respond to situations that arose under the Articles of Confederation, in which the inability of states to coordinate their economic and defense policy led to collective action problems whose effects spilled across state borders. And yet that argument failed to persuade Chief Justice Roberts to uphold the ACA as a legitimate exercise of Congress"s power under the Commerce Clause. It seems more likely that Chief Justice Roberts"s decision to uphold the Act under the taxing but not the commerce power reflected his longstanding commitment—first expressed during his first term as Chief—to persuade his colleagues to put the institutional interests of the Court above their own ideological


The increase of distributed generation in a worldwide level, combined with its characteristic of operating under load imbalance between phases, motivated the study of various aspects of its operation, such as the analysis of possible low-frequency oscillations and the generation penetration level that meets the minimum energy quality criteria. Among the features that deserve a careful scrutiny, there is the investigation of the distributed synchronous generator dynamics under severe operating conditions, including the relevant dynamic associated to its control loops. In this context, this paper presents an analysis of the actuation of the under-excitation limiter, when operating in synchronous generators subject to load imbalance between phases. In addition, the effect of different representations of the generator terminal voltage transducer (which is used as a feedback signal to the excitation system and its associated elements) on the actuation of the under-excitation limiter was evaluated. The obtained results show that significant levels of imbalance, associated with certain terminal voltage transducer representations, may have an adverse impact on the actuation of the under-excitation limiter.


The financial structure of the state budget is a particularly important objective at the national level, aimed at ensuring economic security by providing resources to meet general objectives of national interest. During the - epidemiological crisis, due to changes in expenditure and revenue structures, the state budget was subject to financial pressures, accumulating deficits five times higher than in the period that followed the previous crisis of 2009-2012 and three times higher than at the beginning of the epidemiological crisis. The present scientific approach observes the main causes of vulnerability and identifies the economic and financial directions predicted based on the results of the last 10 years, taking into account the fact that economic security is a major objective that must be permanently monitored and adjusted through sustainable financial policies by institutional decision makers. This study uses prescriptive analytics methods, modelling data or financial results expressed in the national budgets from 2013 to 2021 in order to quantify the vulnerabilities that led to a large budget deficit (sau "an increased budget deficit"). The results may prove to be useful to stakeholders, institutional decision makers or for the medium-term adjustment of financial policies.


Objective:To analyze the occurrence and distribution of adverse drug reaction(ADR) to improve the rational administration of drugs in clinic.Methods: By using the method of retrospective study,97 ADR reports were analyzed.Results: Antibiotic was the drugs causing most ADR,with a proportion of 63.92%(62/97),and system-organ damages were common in skin and appendixes with a proportion of 58.10%(61/105).Conclusions: If supervision of the ADR is strengthened,the rational administration of drugs will be improved in clinic.


OBJECTIVE
To evaluate the survival rate after pulmonary resection for metastatic colorectal cancer(CRC).

METHODS
Clinical data of 77 patients with pulmonary metastasis from CRC between January 2005 and October 2008 in the Zhongshan Hospital, Fudan University were retrospectively analyzed.

RESULTS
There were 38 patients with synchronous pulmonary metastasis, of whom 2 underwent resection for pulmonary metastasis. The median survival time of two groups was 25 months and 18 months, which was not significantly different (P=0.33). There were 39 cases of metachronous pulmonary metastasis, of whom 28 received pulmonary metastasis resection. The 1-year and 3-year survival rates of 2 groups were 93.3% and 58.5%, and 38.8% and 19.1%, respectively. The median survival time of two groups was 26.7 months and 8 months, and the difference was statistically significant (P=0.004).

CONCLUSION
Surgical resection can improve the survival rate in patients with pulmonary metastasis from colorectal cancer.


Fiber-optic seismic sensors (FOSS) consist of an optical fiber connected to an optical interrogator, which is electro-optic instrumentation that injects pulses of coherent light into the fiber and receives and demodulates the returned signals. The optical fiber is usually contained within a protective cable. Experiments were performed on a barrier island setting where several kilometers of cable had been buried at sub-meter depths. It has been hypothesized that seismic disturbances strain a segment of the optical fiber thus causing its optical path length to change. An array of eight 3 axis seismometers were buried alongside the cable at the same depth, with a spacing of 0.5 m, and with one axis parallel to the cable. An electromagnetic shaker, buried at the same depth and in different configurations with respect to the array and the FOSS, was excited with a 10-cycle tone burst varying in frequency from 10 to 200 Hz. The resulting seismic waves were simultaneously recorded with the seismometers and the FO...


Abstract Conceptual modeling of bibliographic data, including the FR models and the consolidated IFLA LRM, has provided an opportunity to shift focus to entities and relationships and to support hierarchical work-based exploration of bibliographic information. This paper reports on a study examining the complexity of a work's bibliographic family data and user interactions with data visualizations, compared to traditional displays. Findings suggest that the FRBR-based visual bibliographic information system supports work families of different complexities more equally than a traditional system. Differences between the two systems also show that the FRBR-based system was more effective especially for related-works and author-related tasks.


We find a gesture which expresses one-half of [the actor's] attitude – that of showing – if we make him smoke a cigar and then imagine him laying it down now and again in order to show us some further characteristic attitude of the figure in the play. If we then subtract any element of hurry from the image and do not read slackness into its refusal to be taut we shall have an actor who is fully capable of leaving us to our thoughts, or to his own. —Bertolt Brecht, 'A Short Organum for the Theatre' (1964: 194) [I]t doesn't take a genius to know that the real problem is capitalism. What leftists call the loss of the political is the fog they wander through because they've lost sight of the communist horizon. —Jodi Dean, The Communist Horizon (2012: 66) Why should I vape? Vaping is an alternative to smoking. It provides a vaper with the sensations, rituals and nicotine that smoking provides, but without smoke and the vast number of dangerous chemicals found in smoke. —vaping.com, 'New Users' Guides: Vaping FAQ


Several new polyimides containing trifluoromethyl groups were prepared from the reaction of various aromatic dianhydrides and two new diamines containing trifluoromethyl groups, 4,4'.bis(3-amino-5-trifluoromethylphenoxy)biphenyl and 1,4-bis(3-amino-5-trifluoromethylphenoxy)benzene. The diamines were prepared from the aromatic nucleophilic displacement of the disodium salts of 4,4'-biphenol or hydroquinone with 3,5-dinitrobenzotrifluoride followed by hydrogenation of the resultant dinitro compounds. The thermally cured polyimides exhibited glass transition temperatures between 186 and 262 C. By thermogravimetric analysis, the polyimides exhibited 5% weight losses at 484-527 C in nitrogen and 452-506 C in air.


This paper presents a method to find a solution of a two-dimensional field problem using finite-difference approach. The finite-difference technique has a slow convergence, but it is simple to program, and has a clear geometric interpretation. In this paper a thin conducting sheet was replaced by a mesh, with variable number of nodes. The potential of an arbitrary point of the sheet was approximated by a function having as arguments the order of the mesh, represented by the number of the nodes, and three unknown parameters. The problem was subsequently solved for several meshes with low number of nods, and the values of the parameters were found by a fitting procedure. The obtained approximating function predicted well the solutions for higher order meshes. There is a possibility that it can also predict the exact solution of the continuous problem seen as an infinite- order mesh for well-posed cases.


Productivity and mortality of grass plants following drought may be controlled by interactions between defoliation and severity of the drought. Prudent grassland management might mitigate deleterious changes in species composition in multispecies grasslands. This study, conducted in a horticultural tunnel, explored the interactions of drought duration, and the period of uninterrupted postdrought growth before defoliation, on phytomass, tiller production and mortality of Aristida junciformis, Eragrostis curvula, Hyparrhenia hirta and Themeda triandra. Pretreatment tiller production was highest for Aristida and Eragrostis, followed by Hyparrhenia and then Themeda. Mortality was positively related to tuft size and drought duration. Tiller mortality was controlled by a species × drought interaction and the covariate tuft-size. All species lost tillers following a 28-day drought, with the highest loss in Eragrostis and lowest in Themeda. Phytomass production was positively related to recovery, and inversely related to drought duration. Species-specific differences in production were apparent only in the no-drought treatment, where Hyparrhenia produced more phytomass than Themeda and Eragrostis. Aristida had the lowest phytomass production and showed little plasticity across drought treatments. Results indicated that postdrought rest is important for phytomass production, and that species may exhibit a tradeoff between productivity and survival.


Combing basic views of western economics and marxism's theory about Interest rate liberalization,this paper believes that the current theoretical basis of the interest rate liberalization conflicts with the principle of contemporary western economics,also does not conform to the principle of monetary action of Marxism Economics,and runs counter to the principle of the state's role in the socialist market economy.Interest rate liberalization or(complete)marketization leads to decreased effectiveness of resource allocation,is not conducive to the rationalization of income distribution and redistribution;Market-oriented higher interest rate will curb demand and thus curb economic growth,the fluctuation of interest rate will disturb economic operation;Market-oriented interest rate will increase and exacerbate credit operational risk,and the financial crisis.The(complete)market reform of interest rate is not a question of the right time or not and how to operate.Instead,the determination of interest rate should not completely release.Scientific interest rate policy should combine controlled market interest rate with the planned/regulated interest rate under the constraints of the market.


On the basis of the traditional theory of Chinese medicine, a Chinese herbal medicine pharmaceutical named "Compound Anti-dysenteric Oral Liquid" was developed to treat diarrhea in dairy calves.And it had the functions of anti-inflammation, anti-dysentericum, stopping bleeding and protecting gastrointestinal mucosa.The dairy calves suffering from diarrhea were treated for acourse of 3 d.The effective rate and cure rate were respectively 70% and 60%, which were higher than those of the control group.Supplementation of flavor enhancers in the oral liquid avoided its poor palatability.Eighty percent of the dairy calves took the oral liquidactively, which avoided the disadvantages of gavage administration.


Background: Nowadays femoral fractures in children are more commonly managed with operative fixation rather than conservative treatment because of more rapid recovery and avoidance of prolonged immobilization. Our aim of study was to assess the outcome of titanium elastic nailing in femoral shaft fracture in children.

Methods: Twenty five children in age group 5-15 years with femoral shaft fracture were stabilized with two titanium nails. Children were followed up for one year. The operative outcome was evaluated using criteria of Flynn. Complications associated with procedure were recorded and analyzed.

Results: The final outcome was excellent in 67% (19 of 25) of patients, satisfactory in 16% (4 of 25) of patients and poor in 8% (2 of 25) of patients. Poor outcome was due to limb length discrepancy, pain in the knee and angular misalignment.

Conclusions: We concluded that titanium elastic nailing is an ideal method of femoral shaft fixation in children.


The article motivates the specifics of regional studies in the aspect of music, reveals its place in the professional education of art college students, represents the module structure of a course "Regional studies in the aspect of music".


Abstract Objective To investigate the role of diagnostic imaging in the clinical diagnosis, treatment, and follow-up management of patients in response to disasters. Methods A MEDLINE (OVID) search of original research articles identified 177 articles on this topic published since 2000. A bibliometric analysis was conducted on the top 100 articles ranked by average yearly citation. Results The most frequently studied disaster categories were disease outbreak (55 articles), armed conflict (23 articles), terrorist incident (10 articles), and earthquake (7 articles). The most studied disasters were the H1N1 influenza outbreak in 2009 (28 articles), Severe Acute Respiratory Syndrome outbreak in 2003 (24 articles), War in Afghanistan, 2001-2014 (8 articles), Iraq War, 2003-2011 (6 articles), and the Sichuan earthquake (China) in 2008 (6 articles). Among the first authors, 59 were primarily affiliated with Radiology. The United States of America produced the most articles (25 articles), followed by the People's Republic of China (24 articles). Eighty-one studies were retrospective, with 19 studies being prospective. Computed tomography was the most investigated modality (52.8%), followed by conventional radiography (33.3%) and ultrasound (9.7%). Conclusions Our study identifies intellectual milestones in the utility of diagnostic imaging in response to various disasters, and could help guide future research in developing disaster management plans. (Disaster Med Public Health Preparedness. 2018;12:265–277)


Surrounding the at least one power electrode, a solderable contact, and wherein the solderable contact formed on the power electrode on the substrate, but the starting silicon carbide device comprising at least one passivation layer to form a gap spaced from the solderable contact do. Solder, the contact and the solder alloy, the passivation, the lead frame


New embryological evidence in angiosperm classification is presented from two different lines of research. One deals with a new field in embryological research, the other keeps within the classical framework. The new approach encouraged by the author refers to the exploration of the chemical composition of the pollen tube as a taxonomic tool. The presence of callose in several pollen tubes and the lack of this compound in others has been correlated with other embryological and taxonomical features within the Tubiflorae, showing a great deal of correspondence. In order to exemplify the classical approach, two families have been selected: Loranthaceae and Hydnoraceae. The Loranthaceae have a special structure called the "mamelon", usually interpreted as a placenta. Recent research based on the position of the ar–chesporial tissue shows that not all "mamelons" should be regarded as homologous structures. Based on this finding, a new scheme of evolutionary lines is proposed. In connection with the holoparasitic family Hydnoraceae, the author discusses its relationships with Mitrastemonaceae and Annonaceae on grounds of embryology and floral morphology.


For inductively coupled oxygen rf discharge plasmas, a global model which consists of the energy and particle balance equations is formulated. The energy balance equation includes energy losses for electron-neutral elastic collision, excitation, ionization, dissociation, pair production, and charged particle wall loss. Particle balance equations are written for all species of interest. For a specified discharge length and diameter, absorbed power, pressure, electron temperature-dependent reaction rate coefficients and surface recombination constants, we solve these equations to determine the densities of all species and the electron temperature. We measure these parameters by the Langmuir probe method. According to the prevailing particle loss mechanism, the parameter space can be divided into a volume recombination-loss-dominated region and an ion-flux-loss-dominated region. Based on the global model equations, the scaling laws of plasma variables with the control parameters for the ion-flux-loss-dominat...


To the Editor High blood pressure (BP) is frequently underdiagnosed in the pediatric population mainly due to the complex diagnosis process,1 which involves the analysis of multiple tables and charts. The BPtoheight ratio (BPHT) is a simple screening tool that has shown good ability to identify high BP in children.2 Conversely, variations in this formula, including the modified BPtoheight ratio (MBPHT)3 and the new modified BPtoheight ratio (NMBPHT),4,5 have been reported to provide better screening performance than the original BPtoheight ratio. However, a recent guideline changed the BP percentiles values in children and adolescents,6 virtually nullifying these findings. Therefore, we calculated new cutoff points for BPHT, MBPHT, and NMBPHT using data from the new guideline and compared the performance of these methods to diagnose high BP in large Brazilian and American populations. This study included subjects that ranged in age from 8 to 13 years and with complete information on height, weight, sex, systolic BP (SBP), and diastolic BP (DBP) from 2 distinct populations. The first population (n = 2936; 1241 girls) was obtained from a database built from medical charts in a pediatric cardiology center in Brazil.3 The second population (n = 6541; 3298 girls) was obtained from data derived from the National Health and Nutrition Examination Survey (NHANES) 19992014.7-9 Only the first BP measurement was used in the analyses and details regarding the acquisition of data are reported elsewhere.3,7-9 BP disorders were defined as SBP or DBP ≥90th percentile and hypertension was defined as SBP or DBP ≥95th percentile according to the most recent guideline.6 The BPHT formulas were: SBP or DBP (mm Hg)/Height (cm). The MBPHT formulas were: SBP or DBP (mm Hg)/7 × (13 − age [in years]). The NMBPHT were: SBP or DBP (mm Hg)/3 × (13 − age [in years]). Receiver Operator Characteristics (ROC) curves were plotted to identify optimal SBP and DBP cutoff points to identify BP disorders or hypertension. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were


The pineal gland transduces light–dark cycles for the timing of body rhythms by secretion of melatonin, an endogenous indoleamine derived from tryptophan, the concentrations of which in plasma and cerebrospinal fluid are up to 100 times higher at night than in the daytime. This exerts its effects through transmembrane, G-protein coupled receptors (MT1 and MT2), and nuclear receptors primarily in the suprachiasmatic nucleus, pars tuberalis of the pituitary gland and hypothalamus. The natural period of the human circadian system is on average 24.1 to 24.3 h, and the principal resetting agent is light. Exogenous melatonin can shift the timing of the internal clock to earlier and later times, and synchronize a free-running clock that is not properly entrained to the 24-h day, hence it may have a therapeutic role for disorders of sleep rhythm including jet lag, in shift workers, and in blind people.


Abstract Reductive dechlorination of chlorophenols (Pentachlorophenol, three tetrachlorophenols (TeCPs), six trichlorophenols (TCPs)) with zero valent zinc was examined through batch experiments. Zinc showed much higher reactivity towards PCP than iron and amended iron indicating that zero valent zinc can be a good candidate for reductive dechlorination of chlorinated phenols. Chlorophenols were sequentially dechlorinated and less chlorinated phenols were identified as reduction products. The mass balance was not complete, indicating that by‐products are important and /or that products being measured were lost by unknown pathways. The dechlorination rate of the chlorinated phenols usually followed the order: PCP > TeCPs > TCPs. Among the TeCP and TCP isomers, the reactivity was in the order of 2,3,4,5‐TeCP > 2,3,4,6‐TeCP > 2,3,5,6‐TeCP and 2,3,4‐TCP > 2,3,6‐TCP > 2,3,5‐TCP > 2,4,6‐TCP > 2,4,5‐TCP > 3,4,5‐TCP. The first order reaction rates varied by one order of magnitude or more, depending on the chlorines positions on a phenol ring. A regioselectivity was observed and daughter compound distributions could be rationalized by a mechanism in which radical intermediates were more stabilized by chlorine and hydroxyl groups than by hydrogen; positions a to the radical were found to be the most important in stabilization, followed by β‐positions.


Today, with the rapid development of computer technology, communication between computer and modern energy instrument Xinxing is extremely important. Serial communication is widely used in on-line monitoring of process quantity in industrial enterprises. This paper analyzes the characteristics of this serial communication, and expounds the selection of communication mode for computer business, the connection of interface hardware and the programming of software. Ethernet technology is currently widely used in the industrial field. Because computer serial communication has shortcomings such as short communication distances and low transmission speeds, meanwhile, process quantity signals have many types, large differences in value ranges, and continuous changes. The key technical issues such as long-distance transmission of travelling signals, real-time communication and display of process volume change curves must be properly resolved before a practical online monitoring system can be constructed. Or it has important reference value for personnel engaged in serial communication between computers and Ganneng instruments.


This qualitative research study explored clinical practices most effective in helping people who experience co-occurring psychosis and a trauma history. The research was conducted through interviews with nine mental health professionals, who reported they created their own skill base in working with clients with a co-occurrence of psychosis and trauma. Although every respondent reported this co-occurrence as common, they all expressed a lack of confidence and expertise in treating the population. Best practices for treatment were found to be a combination of psychiatric medication, psychotherapy, and community support. Themes of treatment included the need to establish trusting relationships, appreciate client strengths, and support clients in making meaning of their experiences. Practices reported as helpful for treating psychosis were sometimes considered contraindicated for trauma. Respondents identified increased tolerance for strong emotion and an expanded capacity for self-care as positive outcomes for their clients, and treatment goals focused on quality of life. EXPLORING CLINICAL BEST PRACTICES FOR WORKING WITH THE CO-OCCURRENCE OF PSYCHOSIS AND A TRAUMA HISTORY A project based upon an independent investigation, submitted in partial fulfillment of the requirements for the degree of Master of Social Work.


Transformer bushing is an important electrical equipment used in power system, it is important for field testing technology of transformer bushing. There are many feature amounts can be used to reflect transformer bushing insulation condition, which including dielectric loss, leakage current, capacitance, insulation resistance, bushing temperature, transformer oil component, SF6 gas components, the frequency domain dielectric spectroscopy, bushing voltage, the most representative feature amount is the dielectric loss, this paper summarizes the measurement methods and research status of insulating feature quantity, introduces data processing method in detection system. Interference issues and reliability issues are problems encountered in field testing, it need to take measures to suppress interference, enhance reliability, and a number of direction for further research in bushing field testing technology is proposed.


The magnetic viscosity of sediments, as indicated by thermal demagnetization of natural remanent magnetization (NRM), depends on two main parameters: (i) the specific magnetic viscosity of the mate...


Background: Dermatoses affecting the palms and soles are more common in our day-to-day practice, because they are most frequently exposed to various allergens, mechanical stress and infectious agents than any other parts in our body. Apart from the diagnostic difficulties, few palmoplantar dermatoses cause great discomfort and disability and may also affect a persons livelihood. Aim:To study the clinical features and frequency of involvement of various palmoplantar dermatoses and their epidemiological aspects like age, sex distribution and occupation. Methodology:100 patients with palmoplantar dermatoses diagnosed clinically attending the OPD in our Department, from 1st March 2021– 31st August 2022 were included in the study. Patients with complaints primarily pertaining to palms and soles with or without involvement of other body parts of all ages and both sexes were enrolled in the study. Investigations such as direct microscopic examination of scrapings, wet mount with potassium hydroxide, Woods lamp examination, patch testing and sample for biopsy was taken. After taking consent, a detailed history and clinical examination pertaining to the aim of the study was recorded and analysed. Results:A total of 100 patients were enrolled, among which 63 were males and 37 were females. The most common age group affected was 17-40 years. Seasonal variation was reported in 41% of patients. The most common symptom was pruritis. Eczema was the most common palmoplantar dermatoses, followed by psoriasis and fungal infections. Majority of patients had involvement of both palms and soles. Conclusion:Palmoplantar dermatoses are very frequently encountered in the dermatologic field. Early recognition of clinical symptoms and signs aids in diagnostic investigations and helps in appropriate and effective management of illness to improve the quality of life. This study highlights the need for comprehensive studies in palmoplantar dermatoses.


According to action structure and teaching character of Apart leg jumping house vaulting, it talks about the difficult and important points in its teaching, This essay try to analyze the main reasons that lead to the common mistake actions in teaching form psychology factor, body quality and technique concepts, in addition, it provides the prevention and methods to corrcet the mistake actions.


Dissolved oxygen (DO) concentration profiles were characterized during the aerobic organic substrate removal phase in a sequencing batch reactor (SBR) for the treatment of a chemical industrial wastewater. In the initial stage (0–10 min), DO concentration rose sharply to a peak level. Subsequently, the DO was slowly decreased and approached a plateau during the COD removal phase. When the organic substrate was consumed, the DO concentration rose sharply from the previous plateau. This was an indication of the end of the COD removal phase, and showed an inflection point on the DO profile. At a fixed aeration rate, the initial peak DO concentration was related to the initial COD concentration. The initial COD can be estimated based on on-line monitoring of the initial DO data. Changing the aeration rate to control DO at a proper level (about 2 mg/L) during the initial stage (10 min) not only ensures oxygen supply and saves aeration energy, but also simplifies operational management. A method of fuzzy contro...


Objective: To evaluate pre-operative risk factors have impact upon post-operative outcome in terms of pain and functional improvement after surgical decompression of lumbar spinal stenosis.
Methods: Retrospective analysis of prospectively data was collected for LSS patients from backache care service until 6 months post-operatively. Neurological and medical factors were identified and were assessed in terms of post-operative improvement in VAS pain scores as well as ODI functional improvement.
Results: Forty five patients were included with 62.2%(n=28) males & 37.8%(n=17) females. Mean age was 61.98 years ± 7.06 SD (range: 47-75 years). Mean duration of symptoms was 27.11 years ± 8.88 SD, 80% of patients achieved effective pain relief and favourable functional improvement. The pre-operative risk factors included tobacco use (24.4%), mostly in the form of 'Naswar'. Comorbid conditions were present in 46.7% patients and included diabetes (15.6%), hypertension (11.1%) and osteoarthritis (8.9%), 13.3% patients had history of previous spine surgery, mostly for prolapsed lumbar intervertebral disc. Surgery was significantly associated with improvement between pre- & post-operative pain scores and ODI scores (p < 0.001). Tobacco use was significantly associated with poor pain functional improvement (p = 0.001). No association was found for gender (p = 0.64), age (p = 0.094), comorbids (p = 0.88), duration of symptoms (p = 0.67) or previous surgery (p = 0.82) for predicting post-operative prognosis.
Conclusion: Surgical intervention is a good choice in relieving pain and disability due to lumbar spinal stenosis. Tobacco use is a risk factor strongly associated with poor outcomes.
Keywords: Lumbar spinal stenosis, laminectomy, surgical outcome, pre-operative risk factors.
Abbreviations: LSS: lumbar spinal stenosis, EPR: Effective pain relief, ODI: Oswestry disability index, VAS: Visual analogue scale


We have developed a 200 mm magnetooptical disc using an exchange-coupled GdFeCo/TbFeTi layer and a heat-sink reflective layer of AlTi. Magnetic properties were measured and reported. It was confirmed that this disc had high writing sensitivity suitable for a speed of more than 3600 rpm, high carrier-to-noise ratio, high reflectance and interchangeability under the condition of a high data density of 0.46 µm/bit.


Subject
 Mounting questions over Fed independence.

 Significance
 President Donald Trump has again publicly criticised the Federal Reserve (Fed) for raising its benchmark interest rate. In July, he first violated White House protocol, of refraining from commenting on monetary policy. Although the White House press secretary immediately assured the public that the president respected and recognised Fed independence, Trump's criticism escalated in September, after the Fed raised the benchmark rate for a third time this year to 2.0-2.25% and signalled plans for a fourth increase in December. Trump described the Fed as "crazy", "wild" and "ridiculous", and making "a big mistake".

 Impacts
 Almost half of Republicans view the FBI poorly after Trump's criticism; confidence in the Fed may also suffer.
 Trump's attacks on Fed policy are likely to grow as the presidential election draws nearer, particularly if economic growth slows.
 More than 50% of Hillary Clinton voters but fewer than 33% of Trump voters believe the Fed aids economic stability; the gap may widen.


The BiFeO_3 sintered body with rhombohedral perovskite structure was prepared under high temperature and high pressure conditions.The sintered samples were characterized by X- ray diffraction(XRD) and field emission scanning electron microscopy(FESEM).The effects of temperature,pressure and temperature holding time on the sample's structure and morphology were studied.The results showed that the relative content of BiFeO_3 increases with the sintering temperature.At 500℃,the BiFeO_3 with rhombohedral structure forms and the major product was Bi_(25)FeO_(40).At 800℃,the purity of BiFeO_3 was highest and the morphology of BiFeO_3 was massive particles with a smooth surface.Under low pressure,Bi_2Fe_4O_9 with orthorhombic structure generated and decomposed with the increase of the pressure.Under4 GPa,the product sintered with a short time was the mixed phase of BiFeO_3 with rhombohedral structure and Bi_(25)FeO_(40) with cubic structure.The Bi_(25)FeO_(40) phase decomposed with the extending of the temperature holding time and the product sintered.Finally,the high purity perovskite powder material of BiFeO_3was obtained after treating with dilute nitric acid.


Evidence is reviewed to evaluate whether the term "brain" is justified in referring to the snail's cerebral ganglion. The focus of the review is terrestrial species, with particular attention given to the genus Helix. In accordance with a standard definition of "brain," the cerebral ganglion is found to be differentiated both structurally and functionally. It receives convergent sensory inputs from a variety of anterior sensory organs plus the posterior body wall. Its outputs comprise motor commands directed towards anterior muscle systems, e.g., the tentacles and the penis, as well as premotor commands directed towards executory centers in other ganglia, e.g., the buccal, visceral, and pedal ganglia. Of the three major divisions in the ganglion, the procerebrum and the mesocerebrum are the most differentiated, whereas the metacerebrum is the least differentiated. The specializations of the procerebrum for olfactory functions, and the mesocerebrum for reproductive functions, reflect the importance of adaptations for feeding and mating in the evolution of the Gastropoda. Microsc. Res. Tech. 49:511–520, 2000. © 2000 Wiley‐Liss, Inc.


In order to verify the performance of folding empennage mechanism of certain Unmanned Aerial Vehicle(UAV),differential equation of motion and finite element numerical simulation model of the empennage unfolding mechanism were established based on Lagrange's Equation and Finite Element Method respectively.The results of folding empennage unfolding motion law solved by using these two methods agree well.On basis of this,it was found through analysis that empennage unfolding time of the original design can meet the design requirement,but the impact load exceeds the design index.Finally,starting from relationship between work and energy,the loading method of driving torque of the unfolding mechanism was improved,the improved scheme can satisfy the design requirements very well.


Objective: There remains a significant risk of chronic subdural hematoma (CSDH) recurring after treatment. Patient-related predictors and surgical procedures have been investigated in many studies. In contrast, the literature remains scant on reports of the potential impact of dehydration on the admission of affected patients and on the CSDH recurrence rate. Methods: All consecutively admitted patients with CSDH and surgical treatment at the authors' institution between 2015 and 2019 were retrospectively identified. Dehydration was assessed as a blood urea/creatinine (U/Cr) ratio > 80. The association between dehydration on admission and postoperative complication rates, in-hospital mortality, and recurrence of CSDH, with the need for additional surgical treatment, was further analyzed. Results: A total of 265 patients with CSDH requiring surgery were identified. In 32 patients (12%), further surgery was necessary due to the recurrence of CSDH. It was found that 9 of the 265 patients with CSDH (3%) suffered from dehydration at the time of admission. Multivariate analysis revealed diabetes mellitus (p = 0.02, OR 2.7, 95% CI 1.2–6.5), a preoperative midline shift > 5 mm (p = 0.003, OR 3.3, 95% CI 1.5–7.5) and dehydration on admission (p = 0.002, OR 10.3, 95% CI 2.4–44.1) as significant and independent predictors for the development of CSDH recurrence that requires surgery. Conclusion: the present findings indicate that dehydration on admission appears to be an independent predictor for CSDH recurrence that requires surgery.


LATENT TUBERCULOSIS INFECTION AND DYSLIPDEMIA AMONG REFUGEES ATTENDING A COMMUNITY BASED CLINIC IN GEORGIA By DOLGION ERDENEBAT JULY 23, 2018 Background: Emerging epidemiologic evidence indicates tuberculosis (TB) disease may increase the risk of non-communicable disease, including cardiovascular diseases (CVD). However, limited data exists on the association between latent TB infection (LTBI) and dyslipidemia, a key precursor to CVD. Objective: To determine the association between LTBI and dyslipidemia among newly arrived refugees to the US. Methods: We conducted a cross-sectional study among new refugees who received care at the DeKalb County Board of Health Refugee Clinic, Atlanta, Georgia between 1st October 2013 and 31st August 2014. Eligible participants included adult refugees (age ≥21 years) who had valid QuantiFERON-TB Gold In-Tube (QFT) and blood lipid test results. Participants with a history of TB disease were excluded. QFT was used to define LTBI and dyslipidemia was defined by three blood lipid levels: total cholesterol, high-density lipoproteins (HDL), and triglycerides (TGL). Results: Among eligible participants (n=684), the prevalence of LTBI was 31.9%. Overall 30.6% (209/684) had elevated total cholesterol, 44% (301/684) had low HDL-C, and 40.7% (276/684) had elevated TGL. Participants with LTBI had a similar prevalence of elevated total cholesterol (35.3% vs 28.3%, p-value=0.06) and elevated triglycerides (44.5% vs 38.4%, p-value=0.13) compared to participants without LTBI. Low HDL-C was also similar in participants with and without LTBI (45.7 vs 40.4%, p-value=0.64). After adjusting for age, sex, body mass index and diabetes mellitus, LTBI was non-significantly associated with elevated total cholesterol (adjusted odds ratio [aOR] 1.27; 95%CI 0.89-1.82) and elevated triglycerides (aOR 1.18; 95% CI 0.84-1.67). Conclusion: Among recently arrived refugees in the US, we did not observe a statistically significant association between LTBI and dyslipidemia. Additional research is needed to determine mechanisms that may increase the risk of non-communicable disease in patients with TB disease and infection.


NEJM Catalyst Insights Council members say that clinical and cost data will continue to be the most useful data sources.


The results in this paper provide new information on asymptotic properties of classical models: the neutral Kingman coalescent under a general finite-alleles, parent-dependent mutation mechanism, and its generalisation, the ancestral selection graph. Several relevant quantities related to these fundamental models are not explicitly known when mutations are parent dependent. Examples include the probability that a sample taken from a population has a certain type configuration, and the transition probabilities of their block counting jump chains. In this paper, asymptotic results are derived for these quantities, as the sample size goes to infinity. It is shown that the sampling probabilities decay polynomially in the sample size with multiplying constant depending on the stationary density of the Wright-Fisher diffusion and that the transition probabilities converge to the limit of frequencies of types in the sample.


A method is presented for the calculation of the initial values of the dependent variables and their derivatives when the network equations are mixed differential-algebraic and implicit in the derivatives. That is, it calculates values for W(O) and W(O) for systems of equations in the form q(W,W,t) = 0. The crux of the problem can be revealed as follows: Equations in the above form do not reveal a dynamically independent set of variables. Even if a set is known and initial values are assigned to them, there sti II remains the need to cal cu I ate the i ni ti al values for the remaining variables and for the derivatives of all the variables. This is true even for derivatives that do not appear in the network equations since knowledge of their values simplifies integration of the network equations by a predictor-corrector scheme. The method presented allows initial conditions to be speci fied by a system of equations of the form p(W(O) W(O) 0. ( This corresponds to speci fyi ng the v a I ue,s of the dyn am ic variables in some other methods). If the number of arbitrary initial conditions allowable by q is greater than specified by p, the method will set a sufficient number of elements of W and/or W to zero.


Physicochemical properties of (C6H18N2)H2P2O7·2H2O denoted DHDP are discussed on the basis of X‐ray crystal structure investigation. The compound crystallises in the triclinic system with P$\bar1$ space group. Its unit cell dimensions are a = 13.719(1) Å, b = 14.188(3) Å, c = 9.177(1) Å, α = 108.50(1)°, β = 91.11(1)°, γ = 115.47(1)°, V = 1503.8(4) Å3 and Z = 4. The structure has been solved using direct methods and refined to a reliability R factor 0.0401 for 4778 reflections. The main feature of the atomic arrangement of DHDP is the existence of infinite rows, parallel to the c direction of the unit cell, composed of H2P2O7 groups. These phosphoric rows are organised to create, with the help of the organic cation, large rectangular channels in which the unstable water molecule are located since they have high thermal parameters. Phosphoric anions and organic cations have no internal symmetry. DSC and TG‐DTA show that dehydration occurs in one step. Such dehydration process may be related to the similar environments on the water molecules residing in the channel. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


15095 Background: Colorectal Cancer is the most common non-cutaneous cancer and the most common cause of death from cancer in Ireland. Early diagnosis is essential to improved survival and advanced...


The important development direction of the environment reconnaissance robot system is to form multi robots network distributing configuration.In the collaboration and navigation of multi robots,the accurate location of robots is very important.With the development of the difference GPS(DGPS),it is very common to be used to locate robots,but with the length of the baseline increasing,the precision of the routine DGPS will decrease.In this paper,the virtual reference station(VRS) is constructed through multi robots system,and the algorithm of DGPS is researched based on the VRS,which can avoid the defect brought by the rou- tine DGPS and make robots move in a large zone with a average and reliable precision.Through the GPS static observation data, the effect of the algorithm is validated.


Abstract Abdulrazak Gurnah's novel, Paradise (1994), provides a narrative reversal and revision of Conrad's canonical text, Heart of Darkness (1902), self-consciously returning its colonial gaze from a postcolonial position. The article begins with the contrived narrative optic of reversal in Conrad's novella, and proceeds to examine the similar narrative structure of privileged and obstructed sightlines, and gazes knowingly and unknowingly returned, in Paradise, showing the intertextual relationship between the two works. Paradise narratively re-maps Conrad's colonial route to an African 'heart of darkness', but from the east coast of Africa westwards, and both recreates and subverts the 'topotropography' of Conrad's work and reconfigures the darkness at its heart. Gurnah's narrative about the last of the great East African trading caravans retraces one of the major trading routes from the coast into the interior around the Great Lakes, which in the nineteenth century had become one of the axes of the slave trade. In his fictional transaction with Heart of Darkness, Gurnah shows in Paradise that the corruption of trade into subjection and enslavement pre-dates European colonisation, and that in East Africa servitude and slavery have always been woven into the social fabric.


The "Stanze" are a flight of rooms in the Vatican Palace, ordered by Pope Julius II. to be ornated with frescoes by Raffaello Santi and his disciples. The second of them, called the "Stanza della Segnatura", was painted first, in 1508-12, by Raffaello himself Housing the papal library for some time, the frescoes are usually understood as though brilliant, yet rather conventional representations of the common fields of study for a cultivated renaissance sovereign: science, Christian theology and the arts', all of which when working together are supposed to cause humane virtue in the studying person, as the images of the "Cardinal virtues" on the fourth wall indicate. Yet, the meaning of the images and their intentions reach much farther, thus making the room a climax of modern European self-understanding, its pride and failure: they are the program of a reasonable reigndom over the world, intending to do justice to Man and the world, proclaiming autonomy for the reasonable individual, who is guided, and protected, by the merciful self-revelation of God through Jesus Christ. The threefold order of the world: the laws of nature, divine providence, and esthetic order, is reflected in the three components of human reason: cognition, morality, and esthetic judgment, as they were identified in the three "Critiques" of Immanuel Kant. The complex esthetic qualities of the pictures, the interactions of their symmetries, thus are supposed to express both, the structure of the world and the structure of reason: symmetry gains a semantic meaning, a "spiritual dimension" transcending mere artistic beauty.


Abstract Julolaelaps celestiae n. sp. (Acari: Iphiopsididae), an associate of Archispirostreptus sp. (Diplopoda: Juliformia: Spirostreptidae), is described and compared with other species in the genus. The species is unusual within the genus in having an anal shield that is wider than long. The host was collected from an unknown country in Africa.


In the transfer of oil products from tanker to terminal the oil may spill from ruptured pipes, corroded valves and connectors and old equipment which may pollute water and
air. Rajaee Port in the Persian Gulf is an important terminal for the Bandar Abbas Oil Refining Company (BAORCO). The major goals of this study are the identification of risk areas from trajectory and fate of the oil spills to the management system for contingency plans to protect the local environment. Two models are used. The General NOAA Oil Modeling Environment (GNOME) model is used for oil spill pollution in the sea and the Areal Location Of Hazardous Atmosphere (ALOHA) is applied to identify the trajectory of the evaporated oil spill through the air. The results from both models were analysed to determine the location of risk areas through the water and air around the spill. Previous studies of water and sediment samples analysis were compared and used to verify and validate the model results. The North east of Qeshm Island and the east of Rajaee Port were identified as the high risk areas. The results are used to improve plans which are implemented by BAORCO in order to reduce the negative environmental impacts.


The present invention relates to a method, a processor and a system for improving the accuracy of identification of a substance. The system (10,100) for improving an accuracy of identification of a substance is provided. The system (10,100) includes an X-ray source (64,66,68) configured to generate X-rays, a detector operatively coupled to the X-ray source, and configured to detect the X-rays and output an electrical signal (196,198,200,202,204,206,208,210,212) representative of the detected X-rays, and a processor (190) coupled to the detector and configured to determine whether a relative molecular interference function of the substance includes at least one peak (1056,1058,1060).


We study multi-modal route planning in a network comprised of schedule-based public transportation, unrestricted walking, and cycling with bikes available from bike sharing stations. So far this problem has only been considered for scenarios with at most one bike sharing operator, for which MCR is the best known algorithm [Delling et al., 2013]. However, for practical applications, algorithms should be able to distinguish between bike sharing stations of multiple competing bike sharing operators. Furthermore, MCR has recently been outperformed by ULTRA for multi-modal route planning scenarios without bike sharing [Baum et al., 2019]. In this paper, we present two approaches for modeling multi-modal transportation networks with multiple bike sharing operators: The operator-dependent model requires explicit handling of bike sharing stations within the algorithm, which we demonstrate with an adapted version of MCR. In the operator-expanded model, all relevant information is encoded within an expanded network. This allows for applying any multi-modal public transit algorithm without modification, which we show for ULTRA. We proceed by describing an additional preprocessing step called operator pruning, which can be used to accelerate both approaches. We conclude our work with an extensive experimental evaluation on the networks of London, Switzerland, and Germany. Our experiments show that the new preprocessing technique accelerates both approaches significantly, with the fastest algorithm (ULTRA-RAPTOR with operator pruning) being more than an order of magnitude faster than the basic MCR approach. Moreover, the ULTRA preprocessing step also benefits from operator pruning, as its running time is reduced by a factor of 14 to 20.


This paper analyzes the design of the reversible passage. A new type reversible spiral case passage suitable for large or medium irrigation drainage pumping stations is presented in this paper. Combined with the model test of Weicun Pumping Station, the pump sets with the passage are tested, and the complex characteristics are obtained.The results show that the flow in the passage is smooth and the pump sets work efficiently with high stability.


Library guide for the FIG cluster that includes Anthropology 201 (Introduction to Cultural Anthropology), Psychology 101 (Introduction to Psychology), and Seminar 101 (Perspectives on Learning). General information about Western Libraries and research resources.


In this paper, we consider a downlink SITN, where the densely deployed low earth orbit (LEO) satellites provide backhaul to terrestrial base stations (TBSs) and TBSs serve the ground users (GU) over different bands. Note that the user sum rate is dependent on the user association and backhaul capacity. Moreover, the multi-connectivity feature between TBSs and densely deployed LEO satellites aggravate the inter-satellite interference, which degrades the backhaul capacity. To this end, we propose an interference-aware resource allocation (IRA) scheme to maximize the user sum rate. Specifically, the TBSs can remove the satellites that will fly out of line-of-sight in the matching process by introducing an adjustment coefficient. Accordingly, the searching space of satellites can be reduced and the backhaul capacity can be improved with high time efficiency. Moreover, the user association is achieved by dividing GUs into different groups, while the required user demands can be satisfied. Considering the dense deployment of LEO satellites, with the well tuned adjustment coefficient, the backhaul capacity can be improved over 12%. Moreover, with the increasing user density, the gap between the user sum rate of IRA and the optimal solution can be reduced to less than 4%.


This symposium presents a collection of theoretical and empirical papers that examine the interplay between networks and innovation. A person may require one type of social network to generate a novel idea, then this person needs another network to implement this idea and the third kind of network is needed to connect the organization to the audience members who will evaluate this idea. The symposium reflects the multi-level nature of innovation and examines how different kinds of networks matter at the level of the creative individual, then at the level of an organization, across organizations and how they connect organizations to their audiences. The Social Structure of Recognition: An Audience Perspective on Cultural Consecration Presenter: Erik Aadland; BI Norwegian Business School Presenter: Gino Cattani; New York U. Presenter: Simone Ferriani; U. of Bologna Social Networks and the Ideation Process Presenter: Pier Vittorio Mannucci; HEC Paris Presenter: Jill Perry-Smith; Emory U. When do Neighbour Ne...


Purpose in this study is to find and accused of performance employees the ministry of religion in counseling religion in kabupaten pringsewu and whatever that becomes obstacle barrier performance employees the ministry of religion in counseling held in kabupaten Pringsewu. Of research in the ministry of religious affairs distric pringsewu. Data collection collected by interviews and documentation. Analysis the data used was data analysis qualitative in starting by making data collection, reduction data, and presentation of data and the withdrawal of conclusion. This research using a technique collection, research room namely by data collection through the activities of observation, research, interview documentation to get data clearer in accordance with required in research. In the results of research obtained conclusion on performance counselors religion the ministry of religion in counseling religion in kabupaten pringsewu.The guidance had run quite well where stage the training is do three stages covering guidance, counseling, and lighting. Performance evaluation of among others for the delivery of material, discipline, responsibility, absentee, cooperation. From the study obtained the result that father m.Including extension workers miftahudin religion with the best grades namely 0.91.


It is rare for states to lodge inter-state cases with the European Court of Human Rights because they fear damaging their relations with the respondent states. Yet in 1971 the government of the Republic of Ireland began a case against the United Kingdom. This research uses archival material to reveal the private discussions that took place within the British and Irish Governments regarding the case until its conclusion in 1978, as well as the official communications issued between the governments. It finds that there were distinct differences of opinion and tension between the two governments regarding Ireland v United Kingdom. Anglo-Irish relations were strong enough, however, that the case was largely kept separate from other aspects of their relationship. This article contributes to an understanding of Anglo-Irish relations in the 1970s and to the literature on this and "the troubles", which almost completely neglects Ireland v United Kingdom.


Objective To investigate the effect of recombinant human interleukin-10(IL-10)on proliferation of adventitial fibroblasts and expression of syndecan-4 protein induced by tumor necrosis factor-α(TNF-α).Methods NIH 3T3 cells were cultured in vitro and exposed to 20 ng/mL TNF-α,100 ng/mL IL-10,200 ng/mL IL-10,100 ng/mL IL-10 with 20 ng/mL TNF-α,and 200 ng/mL IL-10 with 20 ng/mL TNF-α respectively.All groups were treated for 24 h in vitro,and were compared with the control group.The ratio of proliferation of NIH/3T3 cells was determined by non-radioactive MTS/PMS assay and the expression of syndecan-4 protein was evaluated by Western blotting using anti-syndecan-4 antibodies.Results Statistical analysis showed that,(1) Compared to the control group,TNF-α significantly stimulated the proliferation of NIH/3T3 cells at the concentration of 20 ng/mL in TNF-α group(P0.001).IL-10 alone had no effect on NIH/3T3 cells growth(P0.05),but significantly inhibited NIH/3T3 cells proliferation induced by TNF-α(P0.01).(2) Compared with the control group,the expression of syndecan-4 protein in NIH/3T3 cells was significantly enhanced by TNF-α at the concentration of 20 ng/mL(P0.05).IL-10 alone had no effect on the expression of syndecan-4 protein(P0.05),but significantly inhibited the expression of syndecan-4 induced by TNF-α(P0.001).Conclusion IL-10 could inhibit expression of syndean-4 protein in NIH/3T3 cells induced by TNF-α in vitro.


Objective: To observation the phenomena and characteristics of the mutations in IdentifilerTM system 15 STR loci.Method: A total of 2318 parentage confirmed cases were analyzed.The mutation events were screened.The mutation rates of STR loci were calculated.The rule and feature of mutation were analyzed.Result: A total of 61 mutation events were observed in 15 STR loci,The mutation rate was between 0-0.22%.The number of mutation loci was between 1 and 2 for 1 case,the ratio of paternal versus maternal mutation was about 4 ∶ 1.Conclusion: STR mutation events were common in paternity testing.The information of 1-2 mutated STR loci should be addition to other stable STR loci with high polymorphism.


The dynamic response of alumina under shock compression was studied using planar impact experiments with different tile thicknesses. Results show steady spreading of the inelastic shock profile with increasing tile width. Further analysis indicates an expected change in failure mechanism in pressures of about twice the Hugoniot Elastic Limit (HEL). HEL decay phenomenon in alumina is probably a measurement artifact, resulting from the relatively slow response times of manganin gauges.


Abstract Sepsis and septic shock are associated with significant mortality among children of developing economies. We review the current concepts in management of shock that are applicable to emergency room in resource poor setting. The emphasis is on simplified definition, early identification, and a time sensitive approach to reverse pathophysiological derangements using clinical endpoints. Pathophysiology of septic shock includes hypoxemia, reduction in cardiac output and perfusion pressure, capillary shunting of blood past the tissue beds and increased oxygen consumption. Early recognition of sepsis/septic shock is aided by presence of fever, lethargy, altered mental states, tachypnea, tachycardia, central-to-peripheral temperature difference, mottled or cool extremities, abnormal capillary refill and reduced urine output. The management recommendations based on evidence include resuscitation of airway and breathing (first 5 min), administration of 40–60 mL/kg normal saline (5–40 min), early initiation of inotrope infusion (dopamine, 10 μg/kg/min; epinephrine, 0.1–0.3 μg/kg/min), ventilation (when indicated) and administration of the first dose of antimicrobials (20–60 min). Some children may require up to 90–110 mL/kg saline in the first hours. Colloids may be considered in patients with malnutrition and malaria. Hypoglycemia should be identified and corrected at the earliest. Little evidence supports correction of hypocalcemia and use of packed red cells (if hemoglobin is < 10 g/dL) in initial resuscitation. Initial therapeutic endpoints includes normalization of tachypnea, tachycardia, systolic blood pressure, peripheral perfusion pressure, normal capillary refill, urine output = 1 mL/kg/hr, level of consciousness, hepatomegaly and central venous pressure = 10 cmH2O. Subsequent endpoints to be targeted include normalization of central venous oxygen saturation, and blood lactate. Vasopressor (norepinephrine) and inodilators (dobutamine and milrinone), and packed red cells may be used for optimizing these indices of global consumption/delivery deficit of oxygen. Ventilation, manual or mechanical if available, should be used.


At the close of the eighteenth century, Joseph-Marie Degerando wrote: "The traveler-philosopher who sails to the farthest corners of the Globe, travels, in fact, along the road of time. He travels in the past. Every step he takes is a century passed. The islands he reaches are for him the cradle of human society." Degerando's words express a perception of the relationship between European and non-European societies that had become widespread by the time he wrote. Native American, African, and Oceanic cultures, instead of being seen as radically separate from those of the West, were incorporated into a panorama of universal history as the functional equivalents of the European past. By visiting exotic locales and observing their primitive inhabitants, the Western traveler could, in a sense, go back in time and see firsthand how his own remote ancestors had once lived. Although this progressive, universalist view of history is most commonly associated with the Enlightenment, its early elaboration owes much to the Jesuit missionary-scholar Joseph-Francois Lafitau, whose massive study Moeurs des sauvages ameriquains, comparees aux moeurs des premiers temps (1724) offered a specific methodology for the interpretation and comparison of disparate cultures. Lafitau drew upon five years of "fieldwork," and he based


Financial news is an indispensable source for both investors and regulators to conduct research and investment decisions. To focus on specific areas of interest among the massive financial news, there is an urgent necessity of automatic financial news annotation, which faces two challenges: (1) supervised data scarcity for sub-divided financial fields; (2) the multifaceted nature of financial news. To address these challenges, we target the automatic financial news annotation problem as a weakly-supervised hierarchical multi-label classification. We propose a method that needs no manual labeled data, but a label hierarchy with one keyword for each leaf label as supervision. Our method consists of three components: word embedding with heterogeneous information, multilabel pseudo documents generation, and hierarchical multi-label classifier training. Experimental results on data from a well-known Chinese financial news website demonstrate the superiority of our proposed method over existing methods.