Summary Groups of mice inoculated with 2 to 4 LD 50 doses of Eastern equine, Western equine, St. Louis encephalitis, poliomyelitis or influenza viruses and treated with maximal non-fatal doses of diethyl ether by inhalation, sodium amytal, paraldehyde, avertin, magnesium sulfate, morphine, Cytochrome C, dithiobiuret or dithiocarbamate, prior to and following inoculation with the viruses, showed no alteration in the courses of the ensuing infections. The theoretical reasons for the use of these compounds in attempts at chemotherapy of virus infections are discussed.


A general strategy leading to the synthesis of two cis-2-methyl-6-substituted piperidin-3-ols is described. syn-(2R,1′S)-2-(1-Dibenzylaminomethyl) epoxide (13) was used as common building block. The key step involved oxirane ring opening of 13 by the nucleophilic lithium aza-enolate of hydrazones 12a and 12b. Subsequent hydrazone hydrolysis and intramolecular reductive amination afforded the alkaloid (+)-deoxocassine and a new C-6 ethyl analogue of this substance in good yields.


A long-neglected aspect of Aristotle's philosophy that has come under close analysis only in recent years is his theory of friendship. One question that is often asked with regard to friendship is whether it is altruistic or egoistic in nature.1 Although in his Nicomachean Ethics Aristotle identifies many types of friendship, my discussion will focus exclusively on personal friendship. Thus, the study of Aristotle's philosophy of friendship leads us to an inquiry into the nature of personal friendship. However, tension is generated in this aspect of Aristotle's thought between his emphasis on achieving personal eudaimonia (happiness) and the importance he places on also helping others to do the same. This tension will be of significance in the answering the question: Does Aristotle's philosophy provide for an altruistic or egoistic view of friendship? I shall argue that personal friendship, in the Aristotelian sense, is a synthesis of both altruism and egoism known as self-referential altruism, which is a concern for others, but only for those who have some special connection to oneself.2 Aristotle distinguishes between three types of personal friendship: good friendship, friendship of utility, and friendship of pleasure. Friendship of utility, which exists only because the agents are useful to one another, and friendship of pleasure, which exists when the agents love one another only for their pleasant qualities, are both obvious forms of egoism, since friendships of these sorts thrive on egoistic motives, namely utility and pleasure seeking. However, in good personal friendships, the


In the late 19th century, Late Medieval murals were found in the brick and granite church of Hedemora, southern Dalecarlia, middle Sweden. Before the walls were re-painted, the murals, which appear to have been in a very poor condition, were drawn by museum draughtsman Olof Sorling. His drawings are kept in the Antiquarian Topographical Archives in Stockholm, and show motifs from the printed Biblia Pauperum. Certain scenes had in fact been copied out of the Biblia Pauperum, such as Gideon and the fleece. The Hedemora murals have never been attributed to any particular artist or workshop and the drawings have never received any scholarly attention. Because of obvious similarities between the Hedemora murals and those signed by or attributed to a late medieval painter, known as Albert the Pearlstitcher or Albertus Pictor, churches such as Harnevi in Uppland, I argue that he was the one who decorated Hedemora church as well. This work probably took place around the same time as Albertus painted the churches of Sala, Dingtuna and Vasteras in the diocese of Vasteras.


The chemical and isotopic compositions of Hawaiian groundwater were studied to locate and evaluate potential geothermal areas. Analyses were made of forty-three samples from twenty-seven wells, two coastal springs, local precipitation, and steam. Three methods of chemical geothermometry were applied: (1) silica, (2) Na--K--Ca, and (3) stable isotope or deuterium-oxygen-18. Based on the silica and stable isotope methods, the most promising geothermal areas are the summit of Kilauea Volcano and the area near geothermal test hole 3 in the Puna district (east rift zone of Kilauea Volcano). There, temperatures calculated from dissolved silica range from about 160 to 275/sup 0/C. Mixing with cooler groundwaters appears to be a significant feature of these geothermal reservoirs. Seawater intrusion, possibly due to thermal disruption of the equilibrium of the Ghyben-Herzberg lens in geothermal areas, tends to interfere with the geothermometry of the Na--K--Ca and stable isotope methods.


Practical teaching link is the important composing part of the whole teaching system in higher vocational education,which plays extremely key role for cultivating students' practical ability and increasing their comprehensive quality.Higher Vocational College in Bohai University advances the construction of practical platform for higher vocational professional talents' training,which plays good advancing role for practical teaching of higher vocational education.Practical platform provides location and practical platform for students in each major to develop practical teaching and practical activities,and promote students' internship and employment,as well as the requirement of enterprises' employment.


This paper examines the claim that pro drop, the possibility to leave out an argument from a clause, is related to morphological properties of the language allowing it. The fact that subjects can be left out in Italian but not English might be related to the fact that Italian is inflectionally rich. We will discuss a couple of language types that make such a link less straightforward, at least on first view. However, even for languages that allow pro drop in the absence of agreement (radical pro drop) and languages that allow or disallow pro drop in specific person/number contexts, or only with specific subject types, morphological properties have been proposed as relevant. We will evaluate these empirical claims and see what can be made of them theoretically. The conclusion will be that it is hard to shake off the impression that morphological properties are related to the pro-drop phenomenon, but that we are still far removed from an overall explanatory theory that (i) leaves no empirical holes and (ii) relates the different types of pro drop in a meaningful way.


The principle of conservation of energy is often demonstrated by means of free fall. In mechanics, states of a body with potential and kinetic energy are energetically compared. Based on the mass concept of relativistic mechanics, energy conservation is considered to be linked with mass conservation. We show that the process of free fall can be interpreted more thoroughly, if the cause-effect principle and the mass concept of thermodynamics are applied. For the first time in the history of physics, the mechanism of energy conversion in free fall can be shown, which is valid for any object, whether body or elementary particle. The phenomenon of falling confirms the following facts to be valid of on a fundamental level: i) The principle of conservation of energy, ii) The equivalence of inertial and gravitational mass, iii) The real mass increase of any object with its velocity, and iv) The continuousness of space and time. At the end of the article we explain why the theory of general relativity is unsuitable to demonstrate the conservation of energy during free fall.


Introduction This month marks the 10th anniversary of the publication of the Black report.' In 1977 the Research Working Group on Inequalities in Health had been convened by David Ennals, then Secretary of State for Social Services, under the chairmanship of Sir Douglas Black, president of the Royal College of Physicians. Its findings were not welcomed by the government when they were published in August 1980,23 but they generated great interest both in the United Kingdom and in other countries. Copies of the "Black report" were initially in short supply until Penguin published a paperback version, whose sales have ensured it a wide readership.4 The central finding of the working group -that there were large differentials in mortality and morbidity that favoured the higher social classes and that were not being redressed by health or social services-became widely known. In the 10 years since its publication new information has become available in four areas in particular: the use of alternative measures of socioeconomic position to index mortality risk; the collection of morbidity data; the comparison of inequalities in Britain with those in other industrialised countries; and the understanding of the causes of the differentials. These four areas are reviewed in this paper.


We investigate the nanoscale damage precursors that will cause laser damage initiation on fused silica surface during KOH-based wet etching. Some nanoscale damage precursors, like impurity contamination and chemical structure defects on different etched surface with a KOH solution, are explored through a variety of testing methods at nanoscale spatial resolution. The etched surface roughness and photothermal absorption level are also studied. The results show that KOH-based etching can keep a good surface roughness, reduce impurity contamination significantly, and thus decrease surface photothermal absorption level. However, it can mitigate little chemical structure defect and has a risk of secondary pollution induced by residual deposition such as K2SiO3. The work can be a reference on using KOH-based wet etching technology to mitigate nanoscale damage precursors of fused silica ultraviolet optics.


The effect of alloying element, namely chromium (Cr) on the microstructures, mechanical characterization and fracture surface of gamma titanium aluminide (Ti Al) has been studied. Micro-hardness and fatigue crack growth tests were performed on as-cast samples with composition of Ti-48at%Al and Ti-48%Al-2at%Cr. Prior to the micro-hardness tests; samples were metallurgically prepared for microstructural and structural analysis using optical microscope and scanning electron microscope. Field emission scanning electron microscope (FESEM) technique was employed to investigate the fracture surface of sample after fatigue crack growth test. Micro-hardness tests results showed increasing hardness value of Ti-48Al alloys when chromium is added. Both titanium aluminide alloys exhibited a nearly lamellae microstructure. However, finer laths of plates in lamellar structure have been observed in Ti-48at%Al-2at%Cr. FESEM micrograph of surface fracture indicates a mixed mode of failure for both alloys.


Objective:To investigate and evaluate the difference of the accuracy of the diagnosis of impacted teeth of the Cone-Beam CT,Helical CT,and the Panoramic radiograph.To estimate the technique of Cone-Beam CT and Helical CT for the extraction of the impacted teeth.Methods:Ninety-three patients with thirty-seven impacted teeth in maxillary and fifty-six impacted teeth in mandibular were examined by Panoramic radiograph.Thirtyone impacted teeth were only examined by Panoramic radiograph,thirty-one impacted teeth were examined by Panoramic radiograph and Helical CT,thirty-one impacted teeth were examined by Panoramic radiograph and Cone-Beam CT.The distance between the impacted teeth and the surface,the length and the breadth of the impacted teeth were measured and the data of Cone-Beam CT,Helical CT,and the Panoramic radiograph were compared.Results:With the measurable index,the data between the teeth and the helical CT and Cone-Beam CT were significantly smaller than that of between the teeth and the Panoramic radiograph(P0.01).The data between the teeth and the Cone-Beam CT were significantly smaller than that of between the teeth and the helical CT(P0. 01).Conclusion:Comparing with the Panoramic radiograph,helical CT and Cone-Beam CT could be used as an efficient method for the diagnosis of impacted teeth.The accurate positions of impacted teeth can be demonstrated clearly by helical CT and Cone-Bean CT.They might play an important role in the diagnosis and treatment of buried teeth.


A management tool for mechanized aquacultural farm operations was developed. The specific operations for mechanized aquaculture farm operations were identified to include; concrete culture/breeding tank design, water quality management, fish record, feed records, feeding, cost simulation, economic analysis of operations and general report on various individual operations. The management tool was a computer programme developed in Visual Basic. The versatility and object oriented capability of Visual Basic was exploited. Appropriate design consideration for concrete culture/breeding tank design was adopted following establishment and standard procedures. Water quality management, feed composition and nutrition requirements were based the minimum acceptable data as recommended for rearing catfish Wayne (2004). Two different sets of production cycle data were obtained from an existing farm, Icon Fishery, Ganmo, Kwara State, Nigeria to validate the programme. The developed management tool was used to stimulate similar production cycle following the prevailing operation condition at Icon Fishery Farm. The result of the actual data from the Icon Fishery show of a profit of N 426,191 in the first data analyzed while in the second data a deficit of N 206,649 was obtained the results of the predicted data also indicated profit of N 485,958 was for the first data analyzed with similar category of data used for the real life data from Icon fishery and a loss of N 70,402 was obtained for the second set of data following the same procedure for the first data analyzed. Data analysis was carried out to determine whether there was a significant difference between observed data results and simulated data results using the method described by Gomez and Gomez (1984) for test of independence in a contingency table, and the results showed a significant difference between the observed and simulated data results. The study revealed that if the aquacultural farm operations are well managed it will not only increase the profit, but also reduce losses which majorly result from high mortality rate. The management tool will make it easier for farmers to manage the various aquacultural operations, and the farmer can even manage the operations from remote areas once the data are captured and reported correctly.


For every organizational development, the administrators have need of a hard target; however it has attainable, as a result as to enlarge motivation as well as to get better the performance of them. As a consequence, objective complexity will make stronger the firm sandwiched between PMS along with managerial performance or else in an extra word; the difficult goal temperate the connection between performance measurement system along with managerial performance. The effect of Organization Culture (OC) on the usage of numerous information systems is important in company's development. In light of the fit among OC and sorts of Internal Survey results in various kinds of are adequacy. The structure can be utilized by administrator to make appropriate OC that is perfect with the utilization of explicit information systems. Culture can be thought of as the whole of convictions, belief systems, practices and qualities common in firms, which can impact organizational control relationship and their reaction to change. The exploratory phase of this research comprises two main phases: extensive review of literature and interview with employees working in the IT companies, Hydearabd. Interview with employees working in the company was done in order to gain more insights into the subject matter. The study consists of items measuring PMS-BSC and EA on a five-point Likert scale. In the present study 240 respondents from IT industry are surveyed as they meet and satisfy the guidelines in determining the suitable sample size for the research. The Multiple regression analysis is used to test the proposed hypothesis. The study results revealed that OC does moderate the relationship among the four BSC Perspectives and EA in IT industries. Index Terms Performance Management System, Balance Scorecard, Employees Attitude and IT firms.


Abstrαct. T h e occurrence of the sandy beach mysids Archαeomysis Spp. (Mysidacea) with epibiontic peritrich ciliates (Protozoa) has been studied. Epibiontic peritrich infestations were found o n four A 陀 hαeomysis species col. lected from the western North Pacific. This study provided the evidence of ex・ istence of a previously undescribed s y m・ biontic association between mysids and epibiontic ciliates. Overall incidence of infestation for Archaeomysis sp., A. kokuboi, A. vulgαris, a n d A. hosting peritrichs averaged 74.7, 75.6, 22.3, and 1.2 %, respectively, with higher incidence in the northern populations for the genus. N o mysids carrying peritrichs w e r e found in specimens taken from central to southwestern Ja. pan. T hus, the attached ciliates were con. sidered to have a cold water a貸inity. Sea. sonal observations over one year sug. gested that the mysid・ciliate association in the northern waters of Japan w a s a year.round phenomenon. The incidence of infested mysids in the harsh zone of sandy beaches w a s noticeably higher than that in the infralittoral bottoms, suggesting that the habitat of host mysids m a y be a factor affecting the in. festation success of the peritrichs.


Is corruption more growth-enhancing than growth-inhibitory? In this article we examine the effect of corruption on economic growth in a non-linear framework by utilising panel of over 150 countries for the period 1984-2009. The principal part of our analysis draws on recently published data about level of corruption reported by International Country Risk Guide. We supplement this with an additional analysis of a second dataset on corruption prepared by Transparency International since the middle of 1990s. Results suggest that corruption levels do not appear to reduce economic growth at all levels. Our analyses confirm that the level of corruption affects economic growth, but this effect is non-linear. Corruption typically enhances economic growth in countries where corruption is low. But once past a threshold, more corrupt practices inhibit economic growth. The results obtained after controlling for fixed effects and endogeneity biases by utilising system generalised methods of moments (SGMM), the most advanced, robust and well recognised technique in the literature.


This study quantifies the variability in ship defense high energy laser (HEL) and high power microwave (HPM) performance due to atmospheric effects in the marine boundary layer relative to a commonly defined standard atmosphere. The atmosphere effects are defined using the worldwide probabilistic climatic database available in the High Energy Laser End-to-End Operational Simulation (HELEEOS) model. The expected propagation performance is assessed at 4 wavelengths (1.0642 μm, 2.141 μm, 3.16 mm, and 12.2 cm) across the world's oceans and mapped on a 1° × 1° grid. Scenarios evaluated are primarily near-surface and horizontal over ranges up to 9000 meters in which anticipated clear air aerosols and thin layers of fog, light rain, and various cloud types occur. Seasonal (summer and winter) and boundary layer variations for a range of relative humidity percentile conditions are considered to determine optimum employment techniques to exploit or defeat the environmental conditions. Optical turbulence impacts and numerous atmospheric particulate/hydrometeor distributions are evaluated based on their wavelength-dependent scattering and absorption effects on HEL/HPM engagement. HELEEOS includes a fast-calculating, first principles, worldwide surface to 100 km, atmospheric propagation and characterization package. This package enables the creation of profiles of temperature, pressure, water vapor content, optical turbulence, atmospheric particulates and hydrometeors as they relate to line-by-line layer transmission, path and background radiance at wavelengths from the ultraviolet to radio frequencies. Physics-based cloud and precipitation characterizations are coupled with physically correct temperature and moisture vertical lapse rates to create realistic atmospheric boundary layer effects. HELEEOS characterizes maritime aerosol environments using the Advanced Navy Aerosol Model (ANAM) or various representations of maritime particulates from the Global Aerosol Dataset (GADS). In the lowest 50 m, HELEEOS defines maritime optical turbulence with the Navy Surface Layer Optical Turbulence (NSLOT) model.


Including additional photos of specimens, full list of modifications and results of analysis, specimen data and a list of characters considered relevant to the Agnostid Problem.


In March 1998, India broke 25 years silence when it detonated a series of nuclear devices in the Rajasthan desert. Having announced it possessed the requisite credentials for membership in the nuclear club in 1974, India quickly disavowed any desire to join, pledging not to develop its capability further. The Pokhran explosions revealed that promise to have been broken. The principal beneficiary of its breaking was a right-wing government seeking to shore up its shaky base with committment to the "Hindu bomb". While most in the West were taken unawares by this sudden bellicosity in the land of Gandhi, more scrupulous observers on the Indian scene insisted it had a clear history. In this book, the author untangles many of the intertwined threads of an important story often poorly understood in the metropolitan West: that the right-wing nationalisms now flourishing in many regions of the world did not emerge fully formed and as if by accident. Their complex genealogies hold the key to comprehending them. Such an understanding is urgently required in India where, the author argues, the BJP's road to power, far from being a temporary detour from the path of secular democracy, may well become a more permanent feature of the country's politics.


Recent work has related the equivariant elliptic genera of sigma models with K3 surface target to a vertex operator superalgebra that realizes moonshine for Conway's group. Motivated by this we consider conditions under which a self-dual vertex operator superalgebra may be identified with the bulk Hilbert space of a superconformal field theory. After presenting a classification result for self-dual vertex operator superalgebras with central charge up to 12 we describe several examples of close relationships with bulk superconformal field theories, including those arising from sigma models for tori and K3 surfaces.


Two species of the genus Sillybiphora Kuznetsov, 1964 are reported from China, including one new species, S. pauliprotuberans sp. nov. Photographs of the adults and the genitalia are provided, and a key for the identification of the species in the genus is given.


This paper investigates tenseless finite clauses in Swedish . In certain contexts the finite perfect auxiliary, ha 'have', is optional. These contexts are finite non-V2 clauses and V2 clauses in which the V2 position is filled by a mo dal adverb, for example kanske 'maybe'. The analysis of these tenseless clauses is present ed in the constraint based lexicalist theory, lexical functiona l grammar. The analysis builds on, and develops, the one presented by Sells (2007).


There is an inherent tendency towards atomization in many Synoptic approaches. It begins with students learning to color-code individual words to indicate their relationship to another gospel. At the more advanced levels, the atomization manifests itself in compiling lists of dispreferred words or preferred changes made to source material by the redactor. Again, the method tends to be wordfocused, identifying and classifying the changes. Noting changes of individual words is a necessary component of Synoptic studies, but it is not without consequences. The preoccupation with sources and hypothesized redactions can be a distraction from answering the important exegetical question, "So what?" Claiming that the change is based on stylistic preferences sidesteps the question. One can claim that Mark's use of the historical present (HP) was dispreferred by Matthew and especially Luke, or that Mark used καί where Matthew and Luke used δέ. But rarely will you find a discussion regarding the exegetical consequences of the change. Most are content to attribute it to stylistics without regard for the exegetical consequences. So why is this problematic? These kinds of changes have been regarded as irrelevant by some since they do not impinge on the propositional content of the text. For example, Streeter classifies the following kinds of changes by Matthew and Luke to Mark as "irrelevant agreements":1 • changes from the historical present (HP) to an aorist or imperfect tenseform; • substitution of δέ for καί; • insertion of full noun phrases where Mark uses an independent pronoun;2 • introduction of ἱδού, which Mark never uses in narrative. Although these changes may not impact the propositional content of the gospel, they do affect the exegesis. Robert Funk observed that conjunctions belonged to a class which he termed "function words," words that are "nearly lexically empty, that is, they have little or no dictionary meaning of their own. However, they are grammatically significant in


Abstract : Volume 2 of this report is a design guide for integral engine inlet separators in the 2 to 15 lb/sec size range. The separators are designed to remove sand, dust, and single foreign objects from the air entering a turboshaft engine. The procedures are based on results of a 30-month program to design and evaluate integral separators in 2, 5, and 15 lb/sec sizes. Also included are procedures developed during the development of an integral inlet separator for the T700-GE-700 engine. A definition of a turboshaft engine environment in terms of sand, dust, and foreign objects is included in Appendix A. Appendix B describes the analysis of individual particle trajectories in separators to predict sand separation efficiency.


With the aim to explore a barrier membrane with stable degradation rate and excellent biological properties for guided tissue regeneration (GTR), a series of PCL/ CS/nHA (100/0,95/5,90/10,85/15,80/20,w/w) composite membranes were composed via freeze drying. PCL/CS/nHA samples were divided into five groups by adjusting the PCL to CS ratio, and polyvinylpyrrolidone was used as porogen. The fabricated membranes were evaluated by mechanical properties, material degradation rate, morphological characterization and biological properties. Through these experiment, we can proved that for a PCL to CS ratio of 95/5 optimal conditions were as follows: porosity 31.25±2.35, water absorption 101.7, degradation 21.3%, tensile strength 19.2MPa, and elongation at break 218.6%. Moreover, in vitro cytologic research revealed that PCL/CS/nHA (95/5) composite membrane could efficiently increased the infiltration of periodontal ligament fibroblasts (PLFs). Finally, cell proliferation assay showed that PCL/CS/nHA (95/5) composite membrane could promote the differentiation and proliferation of PLFs. These results suggested that PCL/CS/nHA ((95/5) composite membrane could serve as a promising barrier membrane for guided tissue regeneration due to appropriate biodegradability, preferable mechanical properties and outstanding biocompatibility.


Angiogenesis inhibitors have been under a great development in the last decade - precisely, since angiogenesis was associated with more than 70 disease conditions. Parstatin has been shown to effectively block angiogenesis and thus, it can be considered as an important molecule in the treatment of neovascular diseases. Parstatin 1-41 peptide inhibits basal membrane or induces angiogenesis with bFGF and VEGF growth factors in the chicken chorioallantoic membrane model (CAM) or in the angiogenesis aortic ring model. The main objective of this project is to clarify the molecular pathway through which parstatin plays a role in the inhibition of angiogenesis and to explore how two specific parstatin peptides (1-26 and 24-41) are involved in this development. For this, rat and mouse models were used (direct angiogenesis in mouse - DIVAA - and rat aortic ring assay in rats) and some cell lines of endothelial cells (MTT and protein extraction tests on Human Coron).
A part of the program which included the direct angiogenesis DIVAA murine model and also other parts of the program, confirmed that parstatin has strong anti-angiogenic properties.
Peptide 24-41 activity did not inhibit angiogenesis, but on the contrary it actually triggered the process. Hence, the submolecule 24-41 seems not to contribute to the inhibition of angiogenesis, but this has to be confirmed with more similar experiments in the future.


This chapter presents an introduction of self-assembly and the principle of molecular recognition. Typical non-covalent molecular interactions between assembled molecules are introduced in detail. The chapter provides examples of self-assembly of oligopeptides, surfactants, DNA, and synthetic polymers to generate functional materials for potential applications in material sciences and biomedical areas. The chapter describes six representative weak interactions they are electrostatic interaction, hydrogen bonding, van-der Waals interaction, π-π interaction, charge transfer interaction and hydrophobic interaction. The stability of assembly was determined to drive by hydrophobic interactions, in addition to hydrogen bond between the Watson-Crick base pairs and the π-π stacking between aromatic nucleobases. The chapter discusses the DNA as a structural scaffold or template for molecular self-assembly in nanotechnology and DNA templated assembly of extended π-conjugated systems and dyes for further applications in opto-electronic devices or sensing and imaging.

Keywords:

π-π interaction;
charge transfer interaction;
electrostatic interaction;
hydrogen bonding;
hydrophobic interaction;
molecular recognition;
self-assembly;
van-der Waals interaction


Nowadays,the historical and cultural cities are facing the sharp conflict between the conservation and use,and the path of sustainable development is a pressing practical problem.Based on the theory of circu-lar economy,this paper presents the organic circulartion,and has a full research of three essential elements,that are prevention——reuse——regeneration.The result shows that the method is systematic,comprehensive,and scientific.


A historical perspective on the concept of gender identity, rootedin the theoretical studies of J. Money, R. Stoller and C. Chiland,provides us with the means of understanding the complexity ofthis notion as a key factor in the development of Narcissism andconstruction of the subject. A clinical case illustrates the author'shypothesis on the performativity of individual experience (and itsreception by contemporary medical practice) and how this mayparticipate in producing constructs of the subject by the subject.


We study the pricing and hedging of defaultable claims under the benchmark approach, introduced by Platen and Heath (2006), with partial information. The model is considered to be driven by an Ornstein–Uhlenbeck (OU) process. We fist convert the partial information model to a complete information model through the innovation process approach by deriving the non-linear filtering equation for the unobservable processes. We then define the total cash flow and use the Schweizer (2008) methodology for hedging the cash flow under the real world probability measure.


This is the second article of a three part series introducing historical museums in Japan and their role in public education on issues of war, peace, war crimes and reconciliation. The first a r t i c l e (https://apjjf.org/../../../products/details/2594) is Takashi Yoshida's "Revising the Past, Complicating the Future: The Yushukan War Museum in Modern Japanese History (https://apjjf.org/../../../products/details/2594)." T h e f i n a l a r t i c l e (https://apjjf.org/../../../products/details/2603) is by Mr. Kim Yeonghwan, the former associate director of Grassroots House Peace Museum (http://ha1.seikyou.ne.jp/home/Shigeo.Nishimor i/) who describes the peace and reconciliation programs that the Museum sponsors.


A case of a 26 year old G3P2AL2 with previous 2 LSCS with incisional hernia containing gravid uterus. She developed ulceration of abdominal wall at 29 weeks followed by burst abdomen at 35 weeks gestation. An emergency LSCS was done with repair of hernia. A healthy baby girl was delivered.


Electromagnetic solids are modelled as undeformable bodies subject to electromagnetic fields. The response functions are linear and describe fading memory properties. Thermodynamic restrictions on the constitutive kernels are re-examined. Next wave propagation is investigated in the form of singular surfaces. The amplitude evolution is derived for plane wave fronts. The thermodynamic restrictions are shown to imply the decay of the waves.


Salinization is the process of accumulation of soluble salts in the soils. Depending on the environmental conditions and causes, the following factors: parent material, depth and quality of groundwater, capillary rise and evaporation play a significant role for the process. To track down the process in its early stage is a great challenge, as the phenomenon usually initiates in the subsoil and optical remote sensing cannot detect it in time. In the present study electromagnetic survey, using EM-38 sensor, in combination with some geostatistical techniques have been applied under various conditions. Assessment of the accuracy of the electromagnetic measurement at various depths was also carried out. In addition, the variability of soil salinity representing horizontal and vertical distribution of salts in discrete and continuous models was mapped. The study shows that it is possible to map soil salinity variability in both discrete and continuous models, using geopedologic map and an appropriate interpolation technique. The study also shows that it is possible to assess and map soil salinity distribution using electromagnetic survey, with a maximum reliability of 64%.


The protandric hermaphrodite Ophryotrocha puerilis possesses one pair of eyes. They are located in the peristomium. Each light‐sensitive organ consists of one sensory cell and one to two supporting cell(s) embedded in a cup‐shaped reflector. The sensory‐supporting cell complex is enveloped by a basal lamina. This lamina is supposed to be identical with the neural lamella. Thus the eyes proper have to be regarded as protrusions from the brain, while epidermal cells seem to differentiate to crystalline cells (reflector) and are deposited onto the sensory complex.


The physicians intervene in the vital deployment of children, young people and adults with decisions that
can mark not only the quality of life of people but, in particular, the border between life and death. In recent
decades, various investigations have been developed on the consequences of malpractice, iatrogenesis and
medical errors. These are practices indicated as the third cause of death in the United States of America. Hese cases show that specific knowledge and skills are insufficient for good professional performance and
refer to problems of another order such as communication difficulties as well as problems to work in teams,
among others. That is, they refer to transversal professional competences.In that framework, the author's
doctoral thesis was presented, which is presented in a synthetic version in this article. In this research it was
investigated to what extent their teaching is prescribed in the curriculum, cross-cutting professional
competencies and professionalism in the medical career in Argentina are taught and evaluated. To finalize
the study, educational policy documents were analyzed in the resolution version, documents of the case
selected for this study were analyzed and surveys were applied to students (N = 140) and professionals
working in health centers (N = 100). This article will present the results of the scales of the Educational
Policies and the classroom more deeply than the results of the institution for issues related to the length of
the text. For the analysis of the data the interpretive method was used.


THERE is not anything very new that I can say about endometriosis and its treatment, so in the time at my disposal I propose to talk in a personal sort of way about some unusual cases of endometriosis affecting the bowel, bladder and ureters. It is not so rare to find small masses of endometriosis in the bowel, but it is not common to meet cases with serious symptoms. The following 4 cases are perhaps of interest. The first I reported many years ago (Blaikley, 1941) at the Royal Society of Medicine: a single woman, Miss S., aged 40, complained of lower abdominal pain for a week before each period, and for some years it had been severe. She said she had had the pain for 20 years in all. Further for 6 months she had noticed constipation which at the time of her periods became complete for 5 days, and in between whiles the stools were very narrowed and tape-like. She had a large irregular mass filling the pelvis and I diagnosed endometriosis. Laparotomy showed bilateral chocolate cysts which Rere removed together with the uterus. The pelvic colon showed an annular constriction about its middle, and above this the bowel was dilated and the wall hypertrophied. I thought the condition was due to endometriosis, but could not exclude a carcinoma for certain. A Paul-Mickulicz operation was performed, with resection of the affected segment, and leaving the two open ends of the coIon on the surface with a Paul's tube in the proximal. (This was before the days of antibiotics, but I think I would do the same today.) On opening the bowel, I found the stricture was so tight that 1 could not pass a pencil through; the mucosa was not involved. She made a good recovery (Figs. 1 and 2). A second patient, M.H., aged 48 years, married with children, complained of life-long constipation and dysmenorrhoea, but in addition for 12 months there had been colicky lower abdominal pain; there was no blood or mucus in the stool. A small swelling in the left side of the pelvis could be felt, and a barium enema demonstrated a localized stricture, about 4 cm. in length. Laparotomy showed a small chocolate cyst and a firm tumour, 3 cm. in diameter, in the colon, where the cyst was adherent. Both were removed and the bowel anastomosed end to end; the tumour, greyish white and not


1550-7998=20 The dilepton production is investigated in proton-nucleus collisions in the forward region using the Color Glass Condensate approach. The transverse momentum distribution (pT), more precisely the low pT region, where the saturation effects are expected to increase, is analyzed. The ratio between protonnucleus and proton-proton differential cross section for RHIC and LHC energies is evaluated, showing the effects of saturation at small pT , and presenting a suppression of the Cronin type peak at moderate pT . These features indicate the dilepton as a most suitable probe to study the properties of the saturated regime and the Cronin effect.


SUMMARY Selection Criteria This review was limited to randomized controlled trials (RCTs) testing the effectiveness of interventions based on psychological models and compared to educational interventions or no active treatment controls. A Cochrane Sensitive Search Strategy for RCTs was used to search Cochrane databases, MEDLINE, EMBASE, PSYCHINFOR, Ingenta, and CINAHL. In addition, the authors hand searched 4 relevant journals and made personal contact with authors. Non-English papers were considered for inclusion.


Curcumin is the main constituent of curry. In its ground state it shows chemo-preventive, chemo-therapeutic and anti-inflammatory effects. For its immunostimulating action it has been considered for the development of drugs suitable for treating AIDS and cystic fibrosis. Further biological action is induced in curcumin by photoactivation: in suitable environmen- tal conditions electronically excited curcumin can act as a singlet oxygen generator. Moreover, cytotoxicity is enhanced by light exposure and antibacterial effects are photosensitized. This work is aimed to understand the photobiological action of curcumin by elucidating the deactivation mechanisms of its first excited singlet state. In particular we find evidence of the role of tautomerization in the excited state by measuring fluorescence lifetimes and quantum yields for such compound dissolved in solvents of different polarity and H-bonding capability. Degradation quantum yield and singlet oxygen generation efficiency were also measured in acetonitrile and methanol. The results emphasize the strong dependence of the deactivation processes from the environment. The deactivation phenomenology can be fully explained by postulating intramolecular proton transfer in the cis enol conformer to be the leading non-radiative deactivation pathway.


The article is devoted to evaluation of efficiency of innovative activity. The authors consider the economic concept of «nonmaterial results of innovative activity» among the related economic categories. This study demonstrates theoretical assumptions of presence of non-considered non-material results of innovative activity, dynamics of their occurrence, possibility of identification and use in management improvement. The authors suggest distribution by groups of focused attention which allows finding a source of new possibilities and resources of the enterprise


Background The impact that communication has on adherence, considering outcomes such as patient satisfaction and recall of the content of encounters with health care providers, has been extensively reported on in the literature. The South African Depression and Anxiety Group (SADAG) developed a specific communication intervention program, which was implemented in a local public sector setting. Objective To investigate the attendance and medication adherence of patients at the specialist psychiatric outpatient clinic of the Helen Joseph Hospital in Johannesburg, before and after the pilot implementation of this program. Methods Included quantitative and qualitative methodologies. The retrospective component included a review of participants' demographic and clinical profile and medication adherence. The prospective, qualitative component included structured pre- and post-questionnaires. Results The typical participant was female (76%), older than 40 years (58.2%) and unemployed (74.2%). Comparing the study and control groups, the communication program resulted in a higher post-intervention booking ratio for the Study group, while the diagnostic category of participants were associated with their understanding of their medication. Discussion Being mindful of the noted limitations of this pilot project, the SADAG program or similar communication intervention strategy, should be a standard operational procedure in local South African state sector clinics.


Objective: To study the effect of clinical nursing on patients' unhealthy emotions, intraoperative blood loss and complications during the postoperative anesthetic period in the treatment of laryngeal cancer (LC). Method: Ninety-eight LC patients in our hospital were collected as researched subjects, and all patients need resection surgery. Ninety-eight patients were randomly divided into the study group (n=49) and the control group (n=49) by random number table. Clinical pathway nursing was used in the study group, and routine nursing was used in the control group. The results of SDS scale, SAS scales, operation time and blood loss volume during operation were compared between the two groups separately after hospitalization, after the operation and before discharge. The complications during the postoperative anesthetic period were recorded, and nursing satisfaction was investigated before patients were discharged from the hospital. Two groups were followed up for 5 years, and 5-year prognosis and survival condition of the two groups were recorded. Results: There was no significant difference in operation time, 5-year prognosis survival condition and SDS and SAS scores after hospitalization between the two groups (P > 0.050). SAS and SDS scores after the operation and scores before discharge in the study group were significantly lower than control group (P < 0.001). In the control group, the scores of SDS and SAS were highest after the operation, and scores after hospitalization were lower than scores after operation, and scores were lowest before being discharged (P < 0.001). The blood loss volume during operation in the study group was significantly lower than control group (P < 0.001). The incidence of complications in the study group during the postoperative anesthetic period was significantly lower than control group (P=0.027). The nursing satisfaction of the study group was 91.84%, and it was significantly higher than 67.35% of the control group (P=0.003). Conclusion: Clinical pathway nursing can effectively reduce unhealthy emotions, blood loss volume and the incidence of complications during the postoperative anesthetic period. This has great potential for clinical application.


This report explains the need for and sets forth the electrical, mechanical and safety specifications for a high-voltage power supply to be used with the intense neutron source. It contains sufficient information for a supplier to bid on such a power supply.


Water pump is the major auxiliary equipment in power plant and its reliability is directly related to the safe economical operation of the whole unit. The step and method analysis on reliability of water pump of power plant are put forward in this paper. As example, trouble analysis and recovery processing of the feed pump have been done and the safety management reference, of the water pump of power plant has been provided.


NG KW AN HOONG SUMMARY One of the importantfunctions of the Coronary Care Unit (CCU) is the continuous and intensive monitoring of cardiac function. To date, many monitoring techniques have been developed and tested. In this paper, both the conventional and computerised monitoring techniques are reviewed and evaluated. It is shown that a computerised system has several defirute advantages over the conventional system, e.g. lower false alarm rate, accurate and fast data processing, retrospective studies. However one also ought to be aware ofthe limitations, ECl'> MONITOR t-1ULTlCHANNEL


That PAINTINDIA is most popular among all concerned with the paint industry in the country in one way or the other is well known. But not so well known is that it is very popular among students of surface coating technology throughout the country. There is a substantial circulation among the student community which finds PAINTINDIA most educative and helpful in their studies and their endeavour to obtain a thorough grasp of all the technological aspects of paints. To PAINTINDIA this student readership is most valuable since these students are the future managers of paint units as the industry expands. It is in this background, the background of the student readership, that this article assumes significance since nowhere in the literature such a compilation on the topic is auailable. It is for this reason that no list of references accompanies this article. The author of this article has spent a lifetime in teaching paint technology and the article reflects his vast experience.


Objective To observe the effect of captopril and isosorbidemononitrate sustained release tablet doses on senile pulmnary heart diseaseand heart failure.Methods 110 patients suffering from senile pulmonary heartdisease and heart failure were divided into observe group and control group randomly,patients in observe group were,on the basis of the routine treatment,given captopril and isosorbide mononitrate sustained release tablet doses,while the controls received only routine treatment.Clinical effect of the two groups was observed and compared.Results ln observe group,obvious rate was 74.5%,and total effective rate was 90.9%,which in control group were 47.2%and 67.2%,respectively.There were significant difference in obviousrates and effective rates between the two groups(P0.01,P0.01,).Conclusion The effect of captopril and isosorbide mononitrate,sustained release,tablet doses on senile pulmonary heart disease and heart failure is excellent with Iess side effects and safe medicament.


Cu2ZnSnS4 (CZTS) thin films were synthesised on glass substrates by sulphurising sputtered metallic precursors in H2S + N2 atmosphere at 500 °C. The influences of the radio frequency (RF) sputtering power on the structure, surface morphology, optical and electrical properties of the thin films were investigated. Scanning electron microscopy, X-ray diffraction, Raman and UV–vis NIR spectroscopy were used to characterise the films. All the CZTS thin films exhibited a dominant kesterite structure. With increasing sputtering power, secondary phases in the films reduced, and the surface became more compact. The optimum quality films with poor-Cu and rich-Zn were obtained when the sputtering power was 90 W, and the optical band gap, carrier concentration, resistivity and mobility were 1.47 eV, 2.07 × 1018 cm−3, 2.37 Ω cm and 1.38 cm2 s−1 v−1, respectively. The optical and electrical properties of the CZTS thin films in relation to the secondary phases were discussed.


One of the major reasons of failure of structures and components is crack. Most of vibrating structures like offshore platforms, aircraft wings, bridges, equipments with rotating parts or with fluctuating loads are susceptible to fatigue damage, which mainly spreads through crack. The propagation of crack may lead to failure of critical components, which causes huge economic losses and sometimes affects human safety also. If the existence and intensity of crack can be identified in early stages, then preventive actions can be taken and failure or accidents can be avoided. Hence crack detection becomes an important factor for vibrating structure. Existing nondestructive testing methods for crack detection are not applicable for in operation crack identification. To achieve in operation damage identification, Operational Model Analysis (OMA) technique is used in present work. OMA identifies modal parameters through output only time domain data measured from structure. The fact that the crack changes the modal parameters can be used to detect the crack through OMA. In the presented work LSCE algorithm of OMA has been implemented and experiments were carried out on a cantilever beam, on a plate and on a rotor. Various Modal Parameters were extracted for all the three structures. Then the crack location was identified using sensitivity technique and proposed modal indices.


Equity As a Social Goal Cathy Buchanan and Peter Hartley Wellington, New Zealand: New Zealand Business Roundtable, The Terrace, 2000 (246 pages)


The precepts of the Almighty Godhead are the first precepts of Pancasila, which animate the other four precepts. The precepts of the the Almighty Godhead have a relationship between humans and the Creator, which then the other four precepts are guidelines for the relationship between humans with one another. This research is a qualitative research using the case study method. 11 students of class fifth Purwotomo State Elementary School No.97 Surakarta were selected as subjects in this study. Analysis of the data in the study used the interactive analysis technique of the Miles and Huberman model. The results of this study indicate that the value of the precepts of the Almighty Godhead has been implemented by students even though in the online learning period with an indication that the three indicators have been carried out, but in its implementation for the first indicator it is still not optimal because the implementation of worship is still not on time and memorization of prayers. daily students are still small. This is mostly due to the factors of habituation, guidance and supervision from each parent. Keywords: Almighty Godhead, Online Learning, and Elementary School


Mountains in West China serve as the water sources and ecological defense for the country. Ecological conservation and construction are the basic to "West China Development. The Bayanbulak model for mountain development is drawn, which includes (1) absolute protection of wild swans and their habitats--the core of the model, (2) sustainable animal husbandry-the main body of the model, (3) standardization and development of tourism-the breakthrough point, and (4) conservation of traditional western Mongolian culture-cultural diversity. The development model for western mountains of China could be likewise drawn as "one core (nature conservation), three spheres (the main industry related with the local land resources, newly developing industry related to local special resources, and conservation of local ethnic culture)." This kind of development model gives priority to regional ecology with a view to the development and conservation of local traditional and new economy and culture, and thus accord with the purpose of "West China Development.


In Finite Media, Sean Cubitt first examines a myriad of situations in which our media have material consequences for the earth and its inhabitants, clearly laying out the need for change on a massive scale. Thorough, complex, and effective, Cubitt's book makes its largest contribution to ongoing discussions of digital humanities in the Anthropocene in arguing that humanity must change its relationship to media by embracing a new eco-political aesthetic. In the midst of what may now certainly be termed a climate crisis, Sean Cubitt's conclusions in Finite Media remind digital humanists once again that all DH must be Eco-critical DH, because each film strip, each Tweet, and each transmission sent within our network have material consequences for this planet Earth. Backing his analyses of this current state of affairs with myriad examples of the material impact of digital technologies, the author argues that this appreciation of media materiality must come to the forefront if we are to overcome a worldwide ecological disaster which refuses a traditional political or economic solution. Cubitt contends that today's "environmental criticism requires an elaborated theory of mediation, a concept that Finite Media attempts to refine by testing it against the story of the materials that media are made of" [Cubitt 2016, 11]. Finite Media is Sean Cubitt's latest book, following projects like Ecomedia, Digital Aesthetics, and The Practice of Light: A Genealogy of Visual Technologies from Prints to Pixels, in which he has previously explored questions of media, ecology, technology, and culture. Cubitt illustrates that media are finite in their ties to material resources which are themselves finite; recognition of this fact and its implications for the planet and its inhabitants then serves as a foundation for a new eco-political aesthetic, a "revolution in communications" [Cubitt 2016, 11]. To this end, in the first half of the book, the chapters "Energy" and "Matter" greet the reader with a deluge of thorough examples of how our media is affecting our world and its ecological resources, as well as those Native and Indigenous peoples and communities in the Global South who are most immediately, tragically, and too often quietly impacted by the material aspects of our media consumption. Cubitt approaches such various topics as the mining and refining of heavy metals and the creation of the Green Mpeg video codec primarily through the lens of political economy, and in a pattern which continues for the length of the book, his argument fluctuates deftly between highly complex theoretical work to concrete case studies. Upon concluding "Matter", the reader is left with a distinct impression not only of our urgent ecological crisis and its ties to our media environment, but also of the inadequacy of the technological, economic, and political solutions with which humans have thus far reassured themselves that things will improve. In the latter two chapters, "Eco-Political Aesthetics" and "Ecological Communication as Politics", case studies recede in favor of a complex work of criticism which begins by asserting that "the usual levers we pull are not going to work" [Cubitt 2016, 215]. In this second half of the book, Cubitt steadily builds momentum, relying upon the previous stories of our media and their materiality in "Energy" and "Matter" to suggest that real change can only come from "a politics rebuilt on aesthetic principles" [Cubitt 2016, 151]. For Cubitt, this means a new appreciation for "the unimagined beauty of a processual artifact in which the human encounters and engages with ungoverned technological and natural process" [Cubitt 2016, 191]. Far from a work which espouses and explores a single point of view, Finite Media instead embraces the truly complex nature of a difficult problem — one which defies an easy answer. Cubitt weaves together not only insights from political


This article takes as its point of departure the view that technological change is a social process involving negotiations between networks of players. The paper aims to inform the debate on technology management by identifying the dynamics of spaces and occasions where technological change is addressed and politicized. It takes as its focus the development of the information technology (IT) systems for manufacturing, known as Enterprise Resource Planning (ERP) systems in Denmark. These systems, which started out 30 years ago as a visionary concept in the US, are now in daily use in Danish firms. This technology has been moulded by the twin forces of stability and negotiability, with the interplay of supplier and user constellations set out in the context of the relative stability of company social systems. The article discusses three spaces within which the social shaping of IT takes place: the user producer segments, the company internal scene and technological context with the competing pull of mass pr...


The paper presents a novel method of suppressing the angular glint, improving the angle measurement precision and providing tracking of the key position of target for stepped-frequency pulse-compression radar by using high range resolution features. This method use high resolution profile to select the scatter center of the target, and measure the angle of the key position of the target. The experimental results show that this method can improve the angular measurement precision.


The financing of terrorism has been a topic of great concern in the international community, especially following the terrorist attacks of the last decade in many nations around the world.
By studying the means through which terrorists gathered resources in order to plan the attacks, and by taking advantage of the globalization of the international financial markets, it is clear that the counteracting of the phenomenon does not depend solely on the domestic legal order of a State, but more importantly through international cooperation.
Our study began methologically, from the analysis of the sources of international public law, European Union Law and domestic law. Soft law acts, such as the recommendations of the Financial Action Task Force on Money Laundering, (an inter-governmental organization which combats money laundering and terrorist financing), were also extremely useful.
In the first part of our study, we begin by establishing the autonomy of part of the notion of financing of international terrorism. The collection of funds to benefit terrorists or terrorist organizations, even though these funds will not be used, in full or in part, in order to carry out a terrorist attack, is, according to the results of our research, an autonomous notion from that of international terrorism. Indeed, a person who finances is responsible, even though he/she does not prove that the funds are used for a terrorist act. It suffices to prove that these funds are contributed to the activity of an organization to be categorized as 'terrorist'.
The second aspect on which the research focuses on, is the reconstruction of a customary international rule which provides for a duty of cooperation in the adoption of measures to counteract terrorist financing. The reconstruction began from the analysis of UN resolution n. 1373/2001, which requires States to adopt measures of domestic law in order to counteract the financing of terrorism. These measures are an essential requirement for an effective international cooperation.
Practice, especially inferred by the reports sent by States to the UN counter-terrorism committee, by the rules of domestic law and by the behavior of the representatives of States at international level, affirms that States must implement all available mechanisms at their disposal in order to execute UN resolution n. 1373/2001. As for opinio juris, a fundamental element to ensure the existence of a customary rule, it is useful to review declarations made by States in intergovernmental fora or during meetings of the Council of Europe, or, in the reports sent to the UN Committee, as established by resolution n. 1373.
Having established the existence of a customary rule providing for a duty to cooperate in the counteracting of the financing of terrorism, we focused on the effects inside the European Union legal order. The analysis began with the main measures for counteracting the financing of terrorism taken in the European Union. They have different nature and juridical basis, as they can be included in one of the three pillars of the Union. EU action has been particularly effective in the context of the counteracting of terrorist financing.
In one example, the EU has transformed into binding acts for Member States measures that were object of mere recommendations by some intergovernmental organisms (Financial Action Task Force).
Among the measures adopted in the context of the EU, we examined the freezing of assets to evaluate how States have executed foreign measures in order to implement the duty of international cooperation.
In an attempt to demonstrate this, we studied several hypothetical scenarios in which a judge of one of the Member States would have to make a decision. We determined that his judgment was contigent on the fact that the request of designation of a suspected terrorist comes from UN resolution n. 1267/99 or 1373/01.
Cooperation in the adoption of measures to counteract terrorist financing is stressed in the European Union legal order. EU has not only encouraged cooperation through the adoption of binding measures on Member States, but has also contributed to the establishment of the customary rule.
Even though the duty of cooperation can be said to be reinforced in a legal order like that of European Union, it has must coexist with other rules existing in the European legal order, such as the rules for the protection of human rights. In particular, measures which freeze assets can violate the right to a fair trial and to an effective remedy, the right to property, the right of reputation and the right to have access to public documents in the EU. How could these rights be coordinated with the customary rule which provides for a duty of cooperation in the counteracting of terrorist financing? Fundamental human rights can be limited, if they are not absolute, but only according a strict criterion of proportionality: thus, if a person suspected for terrorism has not the right to be previously informed, he has nevertheless the right to effective remedy before a national authority competent to the review of the lists.


Abstract Clusters are aggregates of atoms or molecules in the form of microscopic and submicroscopic particles. They are of practical interest in many diflerent contexts. At the same time they represent an inroad to the understanding of condensed matter in bulk, much as embryology is important for the understanding of full-grown organisms. But just as embryonic development illuminates biological laws in peculiar and often unique ways, so recent research on clusters has uncovered a number of laws that are speciJic to submicroscopic particles. As a particularly striking example, one jinds that the conduction electrons in a small drop of sodium, or some other simple metal, form an ordered quantum state in analogy with the ordered electron structure in atoms. As a consequence, small metal clusters form a periodic system like the system of chemical elements—only much larger.


A set of spanning line segments (SLS) is a subset of the edges of a finite polyhedron in E3 such that an arbitrary plane intersects the polyhedron if and only if the plane intersects at least one o...


The healthcare systems around the world have a need to culminate together to stay in tolerable and sustainable range. Thus, a remote healthcare system is the need of the hour which can be ensured by patient mobility. Four vast technologies, namely, Social, Mobility, Analytics and Cloud, can be augmented together to provide a platform where healthcare can be accomplished inexpensively yet flexibly. The social aspect of it focusses on Epidemiology which is the medicinal branch of dealing out and sourcing of diseases prevalent in a particular demography. Mobility focuses on bringing hands on approach to basic amenities by providing an application. Analytics and Cloud ensure the extraction and collection of data; organisation it, processing it and generating output signals, which ensures generation of alerts for patients to monitor health. SMAC in itself is a growing set of technologies clubbed together to integrate solutions of various healthcare problems under one single roof. Keywords-Big data, data processing, Infodemiology, location API, remote healthcare.


The current popularity of digital technology has changed our life styles invisibly. Looking back on the history,we may realize the abrupt emergence of new technologies often tend to destroy the relatively balanced life formations and it is necessary for us inquire into and reflect on the advantages and disadvantages brought about by the digital technology with technological advances. The virtualization of digital technology and the tendency of over-functioning in design are the design inadequacies influenced by technology. Designers in this era need to follow with interest the intrinsic human emotions and intuitive consciousness,pay much attention to tapping the present cognitive experience and get rid of the barriers to product utility from the angle of natural humanity,whichas the characteristics of humanized design,should bring about healthy changes in people's living.


This is aimed to investigate the influence of companies characteristics and corporate govern-ance on income smoothing: and the influence of corporate governance and financial decisions on companies value and on public companies listed on Indonesian Stock Exchange (IDX). Moreover, this study is intended to analyse the causality relationship between income smooth¬ing and firm value of the public companies listed at the Indonesian Stock Exchange IDX). This research used samples of 56 public companies listed on Indonesian Stock Exchange (IDX) for the periods of 2000 to 2005, Data were then analysed using simultaneous-equation model involving two-stage least square method. The results of this research showed that type of industry influenced income smoothing while the others companies characteristics variables and corporate governance practice variables do not influence income smoothing. In addi¬tion, investment decision influenced firm value whreas others financial decisions variables and corporate governance practice do not influence firm value. Finally there is no causality relation between income smoothing with firm value.
Keywords: earning management, income smoothing, corporate governance, net profit margin, operating profit margin


Follow this and additional works at: https://openscholarship.wustl.edu/samfox_art_etds Part of the American Art and Architecture Commons, Art and Design Commons, Art Practice Commons, Cognition and Perception Commons, Cognitive Neuroscience Commons, Cognitive Psychology Commons, Contemporary Art Commons, Desert Ecology Commons, Epistemology Commons, Esthetics Commons, Fine Arts Commons, Linguistic Anthropology Commons, Metaphysics Commons, Philosophy of Language Commons, Philosophy of Mind Commons, Syntax Commons, Theory and Criticism Commons, Theory, Knowledge and Science Commons, and the Visual Studies Commons


Discussions of outgroup activism in support of lesbian, gay, bisexual, and transgender (LGBT) equality reflect two shortcomings. First, such discussions generally present uncritically positive views of ally activism; second, research on ally activism has overly focused on individual allies. The aim of this article is twofold: to suggest that action toward LGBT equality may often be influenced by sexual prejudice and may thus recapitulate longstanding power dynamics between majority and sexual minority groups, and to expand our understanding of ally behavior beyond individuals by presenting an ethnographic study exploring the development of institutional ally identity in a mainstream church that underwent a marked shift from an explicit anti-LGBT to an expressly LGBT-supportive stance. The study employed critical discourse analysis to examine interview, textual, and participant-observation data. Dimensions of individual and institutional ally activism, and potential pitfalls in each, are explored. Suggestions for promoting more constructive collective action are offered.


Objective To evaluate the expressions of survivin and cyclin-D1 in renal clear cell carcinoma(RCCC),and to explore the association between the biological characteristics of RCCC and the expressions of survivin and cyclin-D1.Methods S-P immunohistochemical staining was performed to detect the expression of survivin and cyclin-D1 in 60 cases of RCCC and 20 cases of normal kidney tissue.Results The positive rates of survivin expression and cyclin-D1 expression were 65%(39/60),73.3%(44/60) in RCCC and 5.0%(1/20),25.0%(5/20) in normal kidney tissue,respectively.Significant relationships were found between survivin expression and cyclin-D1 expression and pathology grade,clinical stage,lymph node metastasis.There was a positive correlation between survivin expression and cyclin-D1 expression.Conclusion The experiment suggests that survivin and cyclin-D1 may play certain roles in the oncogenesis and progression of RCCC.Detection of these genes has positive effects on early diagnosis,malignancy determination,prognosis and treatment of RCCC.


As a mechanical engineer working for Tesla Motors, one of the leaders in the industry of electric vehicles, I am aware that there are many problems in the world that currently need solved, but perhaps none are as urgent as the energy crisis. Everyday hundreds, if not thousands, of cars pass by, each one consuming more of the valuable petroleum left on planet Earth. Imagine a time in which humans have completely exhausted the world's gasoline supply. Almost all forms of modern transportation require this cherished resource; without it transportation would regress decades. If this issue is not resolved soon, the way hundreds of millions of people transport will change for the worse. Fortunately, with the gas prices constantly fluctuating, I am not the only one who is concerned with the future of gasoline-powered cars. In the past few years, many people have been seeking alternatives to gasoline. Possibly the most promising alternative to gasoline is electricity. Electricity as a power source has many advantages thus many respectable organizations are pursuing it. There have been many studies dealing with electric vehicles conducted by my employer, Tesla Motors. Recently, in order to make electric vehicles more appealing to the public, I have been asked to skew the data from these studies and report the results in an official statement. I was told to exaggerate the statistics of more than one study regarding electric vehicles, including the efficiency, the performance, as well as its effects on the environment. In addition to exaggerating, I was also told to omit some of the data to make the results more appealing. The position my company has put me in is troubling; as an engineer I know the ethical code I must abide by. Meanwhile, working for Tesla Motors has shown me the value of electric vehicles, and I want them to be used by the masses. To understand my dilemma, one must compare the ethics involved in engineering with the technology in order to see why it so important to have the public favor electric vehicles.


Optical demultiplexing from 160 to 40 Gb/s is performed using a self-pulsating laser based clock recovery. Error free operation is obtained which demonstrates the good jitter characteristics of the optical clock.


Scholarship in the context of 'home' and 'belonging' has shown that these are referential terms that have shifting and fluid meanings. However, 'home' for the foreigner in a strange host (sic) society takes on meaning heightened by multiple issues. Working through symbolic interaction theory, this paper uses stories or short narratives culled from semi-structured interviews with a small group of Black African foreigners and attempts to proble what home and belonging means in a foreign space and context. The notion of home is explored within the context of the foreigners experiences of xenophobia and violence in protest of their presence in the country. Symbolic interaction theory states that meaning is subjective, yet deeply connotative of intersubjective meanings and is thus used in the paper, to contextualise the shifting intersubjectivities of the foreigners. Anecdotal theory which seeks to theorise personal narratives is additionally used to bring further insights into the foreign migrants' lived experiences. Findings reveal that personal experiences of xenophobic violence have created lingering disillusionment about the so called Rainbow Nation, robbing many foreigners of any real sense of belonging in the host space, as well as emphasising the temporariness of the 'borrowed' home. Findings also show that this entrenched the sense of 'difference' of the foreigner. Keywords: xenophobic violence, foreigner, migrant,fear, home, (politics of) belonging, othering


Recently two of the authors of the present paper proposed a model for fracture mechanics based prediction of the S-N characteristics of metallic components with large microstructural defects and supported this by a validation excercise on an aluminium alloy AL5380 H321. Within this presentation the authors extend the study using a number of data sets from the literature. Despite of necessary assumptions for the compensation of partially missing input information the results are fairly reasonable, with the exception of high loading levels where the analyses of two of the data sets yield non-conservative results. The authors propose multiple crack initiation as the potential root of the problem and discuss methods for extending the model for taking into account crack initiation.


This paper mainly focuses on the feature that Wave Power Converter has poor power quality, and combines with the technology of wave power converter now. A wave power controller based on a point absorber Wave Power Converter is designed. The controller is mainly composed of three-phase bridge rectifier and Buck-Boost chopper circuit and it takes respective measures to solve unstable three-phase voltage of the Wave Power Converter as it seeks to make it become a stable direct current. A large number of simulation experiments on the land show that the controller is feasible, which builds the theoretical and experimental foundations for the practical application of point absorber Wave Power Converter. It also provides a solution to the problem of poor quality of Wave Power Converter.


Abstract:This article sheds light on the historical relationship among childhood, the capitalist consumer culture, and nationalism in the Yishuv (the Jewish community) of Mandatory Palestine between the two world wars. It looks at contemporary advertisements and campaigns that targeted children in order to determine whether the cultural category of child-as-consumer, free to choose among products, had by then already emerged in the Jewish urban middle class. The findings demonstrate that standard commercial campaigns, which marketed products intended for children, usually addressed their pitch to parents and not to the children themselves. But there was one major exception: the campaigns for responsible nationalist consumerism—"buy Jewish"—did not hesitate to exploit contemporary Western marketing strategies to manipulate and tempt children directly, so that they would pressure their parents to buy only local, Jewish-produced goods. Nationalism was therefore a central element in consumer culture's penetration of the Yishuv of British Mandate Palestine.


We shall begin with a passage in the Cratylus (397 B) in which Socrates, under the inspiration of his morning colloquy with the pious Euthyphro—the Euthyphro of the dialogue on the characteristically Orphic conception of ' Holiness '—begins, with HermogeneSj the systematic investigation of the correctness of names. They discuss the derivations of the four terms 8t6i, Satfuov, fjpws, avOpunros. Af t e r der iv ing Oeos from $tlv, Socrates proceeds :


We have measured the Raman spectra of ethylene-vinyl alcohol copolymer (EVOH) and poly(vinyl alcohol) (PVOH). Spectra of 88% hydrolyzed PVOH were examined from the partially crystalline solid, from PVOH dissolved in both H2O and D2O, and from films precipitated from these solutions. The spectrum in H2O differs from that of the starting material by disappearance of sharp bands having Raman shift values of 1146 and 1093 cm−1, strengthening of a band near 915 cm−1, decrease in frequency of bands at 480, 1356, and 1441 cm−1, and increase in frequency of bands at 369, 413, 1023, 1371, and 2910 cm−1. The spectrum of the film shows partial reversal of these trends. With D2O as the solvent, the band shifts are slightly different from those listed above and new bands appear. These changes are indicative of loss of crystallinity, change in stereochemistry, and partial deuteration of hydroxyl during dissolution of this PVOH sample at room temperature. © 1994 John Wiley & Sons, Inc.


Fluctuations of the alpha-effect which break equatorial symmetry of the flow in the kinematic Parker's dynamo are considered. We show, that even small (a few percents) fluctuation can leed to the substantial assymmetry of the magnetic field in the hemispheres as well as the propagation of the dynamo wave through the equator plane. We also consider how change of the dynamo number can be used to explain different regimes of magnetic field generation in geodynamo.


The STS-1 mission of the space shuttle is discussed. The launch and orbital operations are described, and the landing is reviewed.


Dinosaurs were the dominant terrestrial tetrapods of the Mesozoic and their ecological roles and biological impact are generally compared with those of mammals in the Cenozoic. This has led to the assumption that dinosaurs were endothermic also (Bakker, 1971, 1979) and there seems to be some evidence in support of this hypothesis. However, this evidence is not conclusive. Could it be that dinosaurs were in fact ectothermic and could their success be explained most simply in terms of a normal reptilian physiology? In this paper I review the published evidence for and against dinosaur endothermy and attempt an assessment in terms of the thermoregulatroy physiology of living animals, and I discuss the success and the extinction of dinosaurs in connection with published data on Mesozoic paleoclimatology. It is argued that endothermy in dinosaurs would have been energetically costly and yet there appears to have been no need for it. Ostrom (1979) complains that critics of dinosaur endothermy merely offer alternatives and do not disprove the arguments of their opponents. This paper attempts to show why dinosaurs (with the possible exception of some theropods) had to be ectothermic. Before proceeding, the four basic descriptive terms used in thermoregulatory physiology should be defined accurately (Cowles, 1940, 1962; McNab, 1978). A poikilothermic animal has no control over body temperature, which follows external conditions, while a homeothermic animal has a constant body temperature. An ectotherm derives heat from external sources (generally solar radiation directly or indirectly) and an endotherm from internal sources (generally metabolic or muscular heat). This paper was written before the AAAS symposium published as Olson and Thomas (1979) and references to papers from this volume are, as a result, brief.


In the Diagnostic Standards of the National Tuberculosis Association, U. S. A., "minimal tuberculosis" is described in the following manner:1 "Slight lesions without demonstrable excavation confined to a small part of one or both lungs. The total extent of the lesions, regardless of distribution, shall not exceed the equivalent of the volume of lung tissue which lies above the second chondrosternal junction and the spine of the fourth or body of the fifth thoracic vertebra on one side." Cases of this type have become increasingly common since the Introduction of mass miniature radiography. On closer examination of these cases, it is, however, obvious that the changes In "minimal tuberculosis" vary quite considerably. They may be of exudative, of productive and fibrotic, of exudative-productive or of fibro-calcific type. It may, therefore, be considered impossible to determine a common prognosis and a uniform therapy for all cases of "minimal tuberculosis." In addition, age, sex, race, general and individual resistance, etc., strongly influence the development of tuberculosis and the therapeutic possibilities. In cases of "minimal tuberculosis" the nature of the changes must, therefore, be carefully stated, cases with identical changes collected and the prognosis and the therapy determined In each separate group. In my opinion, it is only In this way, that greater certainty can be achieved in this question. Such a well delimited group of "minimal tuberculosis," was named by Malmros and myself in 1938 "initial foci." Radiologically these show great uniformity and, on the whole, this probably also holds true as regards the pathological-anatomical changes, which cause the deviations from the normal In the x-ray photographs. "Initial foci" constitute the first changes in post-primary pulmonary tuberculosis (Ranke's stages II and III), and they form the starting point for ordinary pulmonary tuberculosis. Thus, we are dealing here with Incipient tuberculosis In Its earliest form. In order to be able to collect material of this type one of the two following methods may be employed. One consists of taking x-ray photographs at very short intervals of individuals with definite primary tuberculosis until, in some cases, changes of post-primary type develop. The other method, employed by Malmros and myself in an eight-year investigation2'3 consists of following the development of tuberculosis the whole course from the primary Infection until the development of post-primary pulmonary tuberculosis. We put under control for tuberculosis 3,336 indivIduals, of whom 2,902 were students at the University of Lund and 434 probationary nurses from the same town. X-ray photographs were taken


With such a demanding and competitive labor market nowadays it is vital for graduates from universities to have a complete academic education, and goes beyond that, taking into consideration not only the theoretical aspects but the practical activities, experiences and interaction with other areas as well, in order to acquire a systemic view from the performed activities. This study aims to analyze the contribution of complementary activities in the training of graduates students of Accounting at the Federal University of Rio Grande do Sul and to check if the students believe they have the necessary skills and competences the labor market requires, as well as the influence of complementary credits obtained during college. To achieve these goals it was made a quantitative and descriptive survey and a questionnaire to students enrolled between the fifth and eighth semester of the course was applied. The main results found by this analysis were that students consider those complementary activities important and essential for a full academic formation. However, they still have difficulty with the definitions and activities that are taken into account, as well as the understanding of the resolutions and finding the needed information for ensuring the recognition process. The students usually believe that had obtained the necessary skills and competences for effective work with accounting and that they are fit for the job market. It is noteworthy that these results can be used to improve the use of complementary activities and skills and competencies acquired by students


To effectively improve the estimated level of railway vehicles' vertical dynamic responses and provide a more suitable reference for the selection of its secondary suspension damping parameter, this paper has derived the root mean square values analytical formulae of the car body vertical acceleration, the secondary suspension vertical stroke, and the axle box vertical action force for railway vehicles under the random excitation of the track closer to the actual track characteristics. The correctness of the analytical formulae is verified by testing a real vehicle. Then, according to the analytical formulae derived, an analytical design method of the optimal damping ratio for the secondary suspension system is constructed based on the multi-objective programming and single-objective interval constraint analysis, which can be used to find the best trade-off for conflicting performance indices, such as ride comfort, running smoothness, and running safety, and the influences of the system parameters on the optimal damping ratio are analysed. This research can effectively characterize the vertical vibration response of railway vehicles and provide an effective reference for the initial design of the railway vehicle secondary suspension damping parameter.


The angiotensin II type 1 receptor‐associated protein (Atrap) is highly expressed in the heart. We hypothesized that cardiac Atrap may interact with proteins other than the AT1 receptor. To identify novel interacting partners of Atrap, we performed pull‐down assays. In 3 independent experiments, sequencing of the complexes by MALDI‐MS showed that Atrap interacts with the cardiac Ca2+‐ATPase SERCA2A. The physical interaction of Atrap and SERCA2A was confirmed by co‐immunoprecipitation and by surface plasmon resonance (SPR) spectroscopy (Biacore). The binding of SERCA2A to Atrap resulted in a dose‐dependent increase in the SPR signal with a KD of 7.1*10‐8 M. To evaluate the functional relevance of this protein interaction in vivo, the left ventricular function was assessed in WT and Atrap‐/‐ mice. The heart rates (608±8 vs. 585±12 bpm; p=.20) and ejection fractions (65±2% vs. 64±1%; p=.60) were similar in WT and Atrap‐/‐ mice (n=8). The maximum ventricular relaxation (dV/dt max) was significantly decreased in Atrap‐/‐ (652±42 µl/s) compared to WT mice (1139±184 µl/s; p=.01; n=8), whereas peak contraction velocity (dV/dt min) was inconspicuous (‐778±56 µl/s in Atrap‐/‐ vs. ‐782±102 μl/s in WT mice; p=.97). In summary, we identified Atrap as a novel regulatory protein of the cardiac SERCA2A. We suggest that Atrap enhances the activity of SERCA2A and, consequently, facilitates ventricular relaxation.


Bretschneideraceae is reported as new record from Hainan province, China. The present discovery is the southernmost distribution of the family in China, and also the only tropical montane rainforest locality in China. Its distribution and conversation suggestions are discussed as well.


closet door on this subject and Dr Smith is right to advocate the substitution of "smaller community prisons" for "monstrous local prisons." But this will take time. There are things that can be done more quickly and that will eventually make the smaller community prisons more effective. One of them is to improve the training of all professionals, including psychiatrists, who deal with offenders so that they understand fully those circumstances which encourage offences and the psychodynamic considerations underlying the actions of offenders. Experience has shown both that there is a need for this and that there are people in the courts and in the prison service who recognise this. The British Postgraduate Medical Federation in association with the Portman Clinic began last October the first one year, day release course in forensic psychotherapy for professional members ofmultidisciplinary teams working with offenders. One ofthe objects of the course is to enable trainees to detect potentially dangerous developments. Another is to make them better able to assist judges and magistrates by their professional reports to the court. The main object, of course, is to assess and treat offenders according to basic psychotherapeutic principles. It is right to call for a change in culture and a reduction in prison suicides, but these objectives require those concerned with courts and prisons to insist on improved professional forensic psychotherapy. There is now a way to achieve this.


doi:10.1053/j.gastro.2011.03.057. Despite a declining incidence, gastric cancer remains the second most common cause of cancer death worldwide. The causative role of Helicobacter pylori in the disease is widely accepted, although, as yet, no country has instituted population screening and treatment as a prevention strategy. Some investigators have reported that the incidence of gastric cancer is lower in regions where the consumption of allium vegetables (onions, leeks, scallions, chives and garlic) is high. This meta-analysis of observational studies has attempted to synthesise all available published evidence examining this issue. The authors identified 21 studies that included in excess of 500 000 individuals. When the occurrence of gastric cancer was compared between the highest and lowest categories of allium vegetable consumption, the odds of gastric cancer were significantly reduced (OR 0.54; 95% CI 0.43 to 0.65). There was statistically significant heterogeneity between individual study results, but no evidence of publication bias. Summary ORs were similar when subgroup analyses were conducted according to type of study and geographical region. When each allium vegetable was studied individually, there was a significant effect for all types, with the exception of onion leaves, although the effect of the latter was reported in only one study. Meta-analyses of observational studies, such as this one, cannot control for confounding factors such as age, gender, ethnicity and prevalence of H pylori. In addition, there was heterogeneity between studies in the vast majority of subgroup analyses conducted, suggesting that combining the results of these studies may not be entirely appropriate. The exact constituent of allium vegetables that explains the association between their consumption and reduced occurrence of gastric cancer remains speculative. Finally, it is unclear from the authors' report whether this beneficial effect applies to raw or cooked allium vegetables, or both. Nevertheless, this is an interesting study, and perhaps chemoprevention studies with derivatives of these vegetables will follow in regions at high risk of gastric cancer.


Stretchable and biocompatible hydrogel-based strain sensors have considered as promising candidates for flexible wearable electronics in the light of their properties are similar to those of biological tissues. To date,...


241Am has been widely used as a low energy standardized gamma ray and X-ray source for energy and efficiency calibrations. However in the most cases, only three L X-ray Lα, Lβ, Lγ lines were listed. Using a high resolution Si (Li) detector with the help of computer program for spectrum analyzing, we have decomposed these lines into its components. Fig. 1 shows the X-ray and the 26.35 keV gamma-ray spectrum obtained in this Laboratory. It is our purpose in this note to report the relative intensities of all these observed X-rays, so that this source can be further established for low energy X-ray calibration work.


Keywords: PORE WATER VELOCITY ; MASS TRANSFER ; SOIL Reference ECOL-ARTICLE-1997-001doi:10.1029/96WR03192 URL: http://www.agu.org/ Record created on 2005-12-09, modified on 2016-08-08


Introduction: in Uruguay, parental presence during medical procedures in their children is a controversial practice. There is no national research in the field. Neither are there publications asking children, the protagonists.Objective: to learn about the opinion of:
- parents about their wish to be present during medical procedures in their children,- Children about their wish to be accompanied by their parents.
Method: descriptive, observational and transversal study. Anonymous, semi-structured survey to parents and children in a pediatrics hospital and primary health care centers.Results: 126 parents were included in the study. They would like to be present during the following procedures: 91% blood sampling; 89% placement of a venous circuit, 81% vesical catheterism, 77% rachicentesis and 70% endotraqueal intubation. 58 % of parents believe the decision is to be made by de family, the child, or both. 130 were included in the study. . They would like their parents to be present during the following procedures: 93% rachicentesis, 92% blood sampling and 87% vesical catheterism.Conclusions: most children want tobe accompanied by their parents during medical procedures. Most parents want to be with their children and want to be the ones to decide whether to be present or not. Health professionals and institutions need to respect children's rights and adapt their protocols, policies and regulations to every child and family's preference and cultural values.


A dissertation study examining the development and implementation of an education program for homeless children called Hopeful Horizons. The researchers concentrate on the particular problems associated with educating homeless children and their needs, both educational and psychological. Although t


Many studies have documented the extension of the Clostridium difficile epidemic from the hospital into the community, but a comprehensive picture of community-based disease has been difficult to assemble. Now, Mayo Clinic researchers have reviewed data on all C. difficile infections seen in a Minnesota county between 1991 and …


The late blight is until now remaining the most imp ortant disease on potato crop. In this study we used different potato ( Solanum tuberosum ) accessions, which characterized by several R genes. We used accessions with 2, 3 or 4 R genes. The characterization is done by RAPD markers. From many primers used only some gave interesting amplification products. These are not selective for one gene, and seem to be lin ked to one, two or tree R genes.


Model-based HRR signature prediction and matching is a difficult problem due to target variations, lack of model fidelity, and sensor variations. For this reason, model-based HRR signatures often mismatch actual measured signatures. This paper introduces a novel method for predicting signatures by creating a Parametric HRR signature model from existing measured or model-based signatures. The method identifies potential three-dimensional persistent virtual scatterers and estimates their scattering patterns. The result is a parametric signature function of azimuth which better matches available signature data. The model effectively smoothes the signatures along the scatterer tracks. When used with synthetic data the technique helps eliminate model inaccuracies and uncertainties which manifest themselves in scatterer interference predictions. With sparse measured HRR profile observations, the parametric method smoothly interpolates profiles over azimuth. The parameterization method is aided by a Modified Inverse Radon Transform for persistent scatterer localization and a Fourier decomposition for scattering pattern approximation. Results using the predicted synthetic signatures in ATR multi-class problem are presented and compared with the performance based on the original synthetic and measured signatures. Results from these experiments show that this method provides a modest increase in ATR performance for synthetic signatures. The performance with sparse measured data is greatly improved and approaches dense measured data performance.


In February, we presented a review of mobility aids-some, though not manywith serious intent. One reader writes to say that I overlooked his solution to the problem of getting about-a Seeing Eye doll. He means the human, .not the paper, kind. Another reader responds to January's discussion of "free" benefits. He seems to believe there are too many free braille magazines, most of which are religious in character. He says, "Some people seem to think the blind need religion. Well, there are probably heels among the blind as among the sighted, but there are probably a lot of good souls, too." He concludes by saying, "Heard of cases where magazines were sent to dead people. Hope that never happens to me."


The valinomycin-induced H+ uptake in liposomes with reconstituted uncoupling protein from brown adipose tissue mitochondria is greatly enhanced when palmitic acid (4-20 micrograms/mg lipid) is incorporated prior to proteoliposome preparation. This procedure does not change basal H+ permeability of the liposomes. H+ uptake in proteoliposomes is inhibited by GDP, the net GDP-sensitive H+ flux being higher when palmitic acid was incorporated than in its absence. The net palmitate-induced increment of H+ uptake decreases with increasing concentration of GDP. These results suggest that palmitate augments H+ flux via the uncoupling protein and that direct interaction of palmitate with the uncoupling protein occurs during such activation within the hydrophobic core of the membrane.