Background: Left ventricular non-compaction of the myocardium (LVNC) is a morphological trait of unknown significance due to its wide phenotypic expression. Purpose: The aim of this study is to evaluate the genetic etiology in a cohort of patients with LVNC and to establish a genotype-phenotype correlation. Methods: Patients who fulfilled both echocardiographic and cardiac-MR criteria for LVNC were prospectively included and followed up in a familial cardiomyopathy unit. Genetic testing was performed in case of family history of cardiomyopathy, positive family screening or sporadic LVNC cardiomyopathy case (LVEF<50% or other expression). Results: In a cohort of 95 patients with LVNC, 48 (51%) met inclusion criteria and a genetic test was performed being positive in 30 (63%; 32% of the total cohort). Cosegregation analysis has been completed in 19 families (63% of positive index cases) and was positive in 13 (68%). Genetic variants were most frequently found in TTN (titin) and MYH7 (myosin) genes, affecting 7 (23%) and 6 (20%) patients respectively. DSP (desmoplakin) and BAG3 (BCL2 associated athanogene 3) genetic variants were also frequent (4 and 3 patients respectively). Other genetic variants affecting mostly individual families were: CASQ2, DMD, KCNJ2, LAMA2, LDB3, MYBPC3, MYOT, NKX2-5, PDLIM3, RYR2, SCN5A, TBX20, TNNI3, TNNT2 and TXNRD2. In total, sarcomeric genetic variants were identified in 18 cases (60%). The incidence of cardiomyopathy in the global series was 57%. 20 patients with genetic variants (67%) had a LVEF<50%: 12 of these cases (60%) had LV dilatation and 8 (40%) had normal LV. There were no patients with LV dilatation and preserved LVEF. The incidence of cardiomyopathy was even higher among patients with sarcomeric genetic variants (78%). 85% of families with genetic variants presented relatives with LVNC phenotype. Conclusions: The genetic heterogeneity (mostly involving sarcomeric genetic variants as in other cardiomyopathies) found in our series of patients with imaging criteria for LVNC and the differences in the individual and familial phenotypic expression suggest that LVNC would correspond to a morphological trait in a genetic disease rather than a specific cardiomyopathy. Our data suggest a more severe phenotypic expression in patients with LVNC and genetic variants.


Purpose – Following the landmark 2003 Ontario Court of Appeal decision legalizing same‐sex marriage, some same‐sex couples sought to formalize their unions through legal marriage. The purpose of this paper is to explore the personal and political reflections of recently married same‐sex couples on the meaning of their marriages for themselves, their partners, their community as well as the implications for progressive social change in the broader social world.Design/methodology/approach – An ethnographic approach was employed to semi‐structured in‐depth qualitative interviews with six lesbian and gay couples.Findings – An emerging thesis is that, while seeking access to a most conventional and conformist institution, same‐sex couples inadvertently become "cutting edge" couples as they make public their declarations of love and commitment and model new and challenging notions of marriage.Research limitations/implications – The paper provides a snapshot of a small number of interviews that took place approx...


A 29-year-old patient with diplopia showed a unilateral fourth nerve palsy combined with a Horner syndrome on the opposite side. Magnetic resonance images disclosed a focal hemorrhage in the left dorsal midbrain, affecting the nucleus of the fourth nerve and adjacent oculosympathetic fibers. Further evaluations including a bone marrow biopsy confirmed acute lymphoblastic leukemia. The combination of ocular motor and oculosympathetic palsy has a distinct localizing value. Fourth nerve palsy ipsilateral to Horner syndrome locates lesion in the cavernous sinus, while contralateral fourth nerve palsy locates the lesion in the midbrain.


AN rCVS Disciplinary Committee hearing involving Cardiganshire practitioner Dewi Wyn Lewis was adjourned on April 21 after a four-day sitting. Mr Lewis of Priory Veterinary Ltd, Pwlihai, Cardigan, faces a single charge of disgraceful professional conduct relating to tuberculin skin tests carried out on April 6 and 9, 2009, on 104 cattle owned by a client at Moylegrove near Cardigan. It is alleged that he failed to measure accurately the skin folds on some or all of the cattle and that he knew, or should have known, that the measurements recorded on the Official Veterinarian certificate were false. After the committee had heard evidence on behalf of the royal College and Mr Lewis, Sheila Crispin, its chairman, adjourned the hearing until July 18 and 19, when the committee will deliver its findings on the facts of the case.


Introduction: Acute diarrhea is fecal discharge >3 times in 24 hours occurring <14 days. Diarrhea is still a health problem in Indonesia. This study aimed to determine the hematological profile in cases of acute diarrhea in children under five. The hematological profile can help diagnose acute diarrhea.
Methods: This research method is a descriptive retrospective with data from the medical records of patients with acute diarrhea in children under five at Idaman Banjarbaru Hospital in July - October 2018. The sampling technique was carried out using consecutive sampling.
Results: In this study, a sample of 109 children, 65 boys and 44 girls, were obtained. The results showed that 69.72% of the patients had anemia, and 62.39% had iron deficiency anemia (IDA). Leukocytosis and thrombocytosis were found in 16.51%, 23.85% of patients. Basophilia, eosinopenia, band neutropenia, segmented neutropenia, normal, lymphocytosis, monocytosis were found in 100%, 67%, 99%, 67%, 66%, 60%, respectively. IDA is found in 62.39% of children under five who suffer from acute diarrhea.
Conclusion: Typical lab results are the presence of basophilia, eosinophenia, band neutropenia, lymphocytosis, and monocytosis.

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Air pollution tolerance index is used to select plant species tolerant to air pollution. Four physiological and biochemical parameters namely, leaf extract pH, ascorbic acid, total chlorophyll and relative water content were combined together in a formulation signifying the air pollution tolerance index of plants. Plants present in Perumalmalai hill, which is located at Salem District were studied to identify its tolerance to pollution during the month of February 2013. From our study, Nerium oleander having APTI value of 16.65 was identified as intermediate species tolerant to pollution. Whereas, Ficus benghalensis, Psidium guajava, Spathodea campanulata, Opuntia ficus indica having APTI score of 15.92, 15.41, 9.92, 9.74 was identified as a sensitive species. The carotenoid content studied also showed its maximum in Opuntia ficus indica.


E-commerce is a form of trade that is relatively new also can not be separated from problems in its implementation. The problems that arise in the implementation of e-commerce include the validity of contracts in e-commerce (online-contract / econtract) and the strength of the proof of the contract if there is a dispute especially based on the principle of contractual contract. In the field of civilization, a wider problem occurs because electronic transactions for trading activities through electronic systems have become part of national and international commerce. This fact shows that the convergence in information, media and informatics (telematics) technology continues to be unstoppable, along with the discovery of new developments in the fields of information technology, media and communications. Law No. 8 of 1999 concerning Consumer Protection does not specifically regulate consumer rights in e-commerce. In other words, it is difficult for consumers to sue e-commerce businesses with Law Number 8 of 1999 concerning Consumer Protection because e-commerce businesses are very difficult to reach. While the regulations used to regulate e-commerce transactions are Law Number 11 of 2008 concerning Information and Electronic Transactions, but in this law, there are no provisions specifically regulating the protection of consumers against acts of default of business actors in e -commerce. Law Number 11 of 2008 concerning Information and Electronic Transactions is adapted to the development of e-commerce, including the number of cases of consumer losses that arise in the community, due to defaults from e-commerce business actors, so that a provision can be made in this law concerning the protection of consumers against the actions of defaulters of businesses in e-commerce transactions. Restrictions on the principle of freedom of contract can also be concluded through article 1338 paragraph (3) which states that an agreement is only carried out in good faith. Therefore the parties cannot determine at will the clauses contained in the agreement but must be based and implemented in good faith. Agreements based on bad faith such as fraud having legal consequences of the agreement can be canceled.


Organizations are now increasingly expected to address the sustainability of their information technology (IT) and communication infrastructure. This research investigates the antecedents for the adoption of Green IT in South African higher education institutions (HEI), namely which drivers and readiness factors influence Green IT adoption. Green IT comprises of server virtualization, storage virtualization, storage consolidation, environment-friendly IT procurement, electronic waste management policies and measuring the environmental impact of IT. For the purpose of this research, Green IT drivers were classified into economic, ethical, response and regulatory drivers as per Molla's (2008) Green IT model. Additionally, we also investigated the role of the following Green IT readiness factors: institutional, organisational and value network Green IT. IT managers at all South Africa's HEIs were approached through an online survey. Given the small number of HEIs in South Africa, sample size was necessarily limited but the responses received represent a significant and representative portion of the South African HEIs and encouraging results were found. All Green IT drivers were found to be significant antecedents in the adoption of green IT, although the overall adoption of green IT is relatively low. However, most HEI stakeholders in the HEI value network, i.e. suppliers, investors, competitors and government, do not seem to exert a significant influence on green IT adoption. We condensed these antecedents into a revised Green IT adoption model. Our research instrument and proposed resultant Green IT model should be of interest, not only to HEI stakeholder in South Africa and elsewhere in the world, but also to researchers in the field of sustainability of information technologies and the manufacturers of green and sustainable technologies.


Objective To investigate the relationship among CEA, CA199, clinical pathological characteristics and prognosis in patients with rectal cancer. Methods A total of 142 patients diagnosed rectal cancer were collected for the study between January 2006 and December 2010. The clinical data including age,sex, size of tumor, differentiation, depth of tumor(T), lymph node metastasis(N), distant metastasis(M),lymphatic invasion, venous invasion, stage, and preoperative serum levels of CEA and CA199 were obtained.Patients′ follow-up ranged from 42 months to 90 months. Results Preoperative elevated CEA levels were significantly associated with distant metastasis(P 0.05). Median overall survival time was 150 weeks in the group with normal preoperative CEA and CA199, and 101 weeks in the group with preoperative abnormal preoperative CEA and / or CA199, and Kaplan-Meier analysis showed that the difference was significant between two groups(P = 0.031). Conclusion Elevated preoperative CEA level can predict distant metastasis. The patients with abnormal preoperative CEA and / or CA199 have shorter overall survival time.


Objective To evaluate the relation between the autonomic nerves and the ambulatory blood pressure fluctuation in the old hypertensive patients.\ Method\ We selected 100 old essential hypertensive patients (research group) and compared them with 100 age and gender matched normotensive controls(control group).\ The blood pressures were measured with ambulatory blood pressure monitoring(ABPM) and the heart rate valiability(HRV) with ambulatory electrocardiography.\ Results\ The HRV is low in the research group than in the control group.\ In patients in the research group the SD was positively correlated with the MAP (SD=0 09 MAP+24.75,PNN50=0 10 MAP+8.34) and the SD was negatively correlated with the MAP (SD=-0 32MAP+68.87,PNN50=-0 047 MAP+21.65) in the control group.\ Conclusion\ In the old normotensive the relationship between the autonomic nerves and the ambulatory blood pressure fluctuation is in a normal physical condition, representing by that higher BP is associated with lower HRV.\ The abnormalifiens of autonomic nervous system in the hypertensive patients were assumed to reverse the relationship between BP and HRV, manifestating by the higher the BP, the higher the HRV.


System drop protection comprising a central longitudinal reinforcement (2) drop around ofa tube (10) of the armature, of axis XX ', comprising two ends, a fabric (4) derecubrimiento armature, the armature comprising: - at least two pairs (P1, P2, P3, P4, P5) of tubes (20, 24, 28, 32, 36), (22, 26, 30, 34, 38) rigid estandodos rigid tubes of a pair, in a plane (pl1, pl2, PL3, PL4. pl5) respective axial XX'longitudinal passing through the axis, articulated by one end (eA) in a respective fork together, one (40, 44, 48, 52,56 ), to one end of the central tube, the other (42, 46, 50, 54, 58), the other end of said tube (10) center, can the other free ends of the rigid tubes to move in the axial plane torque, - a tube (70, 71, 72, 73, 74) semi-stiff pair of rigid tubes, in said axial plane of the pair, quecomprende at each of its ends a piston (75), wherein each piston a semi-rigidodeslizarse shaped tube sealed in one and another of the rigid tubes of the pair to form a chamber (80) depressurisation in each of the rigid pipes, the protection system further comprising a pressurizing device camera tubosrigidos to move the pistons in the rigid tubes and passing the system to a retracted unaposicion deployed position.


SUMMARY This article focuses on the region called Western Sahara (former Spanish Sahara) and directly related to dialectology and folk traditions, we provide a study on the culinary equipment and instruments used once (although much of it remains today) by the indigenous inhabitants of the region. To this end, we address key issues such as Hassaniya dialect; cooking and food preparation in the traditional survey area; instruments and vessels for the treatment of milk; tools for treatment of grain or the use and utilization of shrubs for obtaining wood, since the vast majority of wooden containers were made of some of the most representative woody species in the area. The approach is basically anthropological, with obvious semantic component, reflected in the generous use of Arab-Hassaniya terminology, with its equivalent in Spanish.


Nautical tourism on the Adriatic Sea represents a particularly significant sector of maritime and tourist activities. The safety of sport and pleasure boats guarantees successful performance of nautical tourism activities. An increasing number of these boats sailing in the Adriatic Sea is important for the overall economic development of the Republic of Croatia and the Republic of Montenegro. In Croatia, sport and pleasure boats are regulated by the Maritime Code, the Ordinance on Boats and Yachts and a number of subordinate legislation acts, while in Montenegro they are regulated by the Law on Yachts, the Law on Safety of Maritime Navigation, the Regulation on Boats and other subordinate legislation. These regulations govern the conditions for navigation, the area of navigation, seaworthiness of yachts and boats, procedure and conditions for acquiring qualifications and certificates for boat leaders, yacht masters and skippers. This paper puts special emphasis on regulatory laws on yachts, sport and pleasure boats, as well as on requirements that must be met in ensuring the safety of navigation. According to the broadest definition, a yacht is a boat designed and equipped for long sea voyages, and it is used for sport and pleasure. However, more detailed analysis indicates the term can therefore be concluded that there are certain differences in the Croatian and Montenegrin legislation, and in this respect the paper will also provide de lege ferenda solutions.


The steady state spatial patterns arising spontaneously in open nonlinear reaction–diffusion systems beyond an instability point of the thermodynamic branch are studied numerically for a simple kinetic scheme. The set of nonlinear partial differential equations, describing the system, is converted to a (large) set of ordinary differential equations. It is stressed that the resulting system is stiff, and must be solved accordingly. An efficient algorithm is outlined, based on Stiff predictor–corrector formulas and sparse matrix techniques, which yield a gain of a factor 470 in computing time over nonstiff methods. The developed algorithm is used to determine quantitatively the primary and first few secondary bifurcations in the sphere, thus simulating a biological cell or early blastula. Spontaneous gradient formation and 'Chemical hysteresis', connected to the occurrence of multiple steady states, is encountered. The succession of stable patterns found for increasing size of the sphere is suggested to act as an ideal mechanism underlying the process of mitosis.


same principles. He also procured instead of the substance intermediate between mucus and albumen, which was found by Lassaigne, another principle, analogous to gelatin, but more soluble in the cold, and destitute of the property of forming a jelly. M. Collard de Martigny winds up his analysis with some judicious observations on the utility of organic chemistry in the diagnosis of diseases. Many examples are now well known of certain diseases being invariably accompanied with certain changes in the secretions. These changes are sometimes cognizable by the external senses; sometimes they require the manipulations of the chemist before they can be ascertained ; and the progress of pathological chemistry is daily adding to the latter list. It is correctly remarked by our author, that organic principles are frequently found in diseased states of the body, which are never found in its healthy state,?, that certain principles seem invariably to be produced during peculiar states of disease,?and that of the diseases attended with discharges, there are probably few in which some peculiar principle may not be detected. It is impossible to foresee the extent to which organic chemistry may be made serviceable in the strictly practical department of the healing art; but enough has been done even alreJdy to show that the physician who neglects it neglects one of the most precise, and, we may even ven-


Abstract:In the poem, "deer in winter," the speaker is burdened by the triage of self, other, and landscape during a time of emotional misunderstanding.In the poem, "understory," the speaker navigates desire and intimacy despite the past's irreparable trauma.


Absorption by CO2–He and CO2–N2 mixtures has been measured as a function of temperature on the J = 16–22 lines of the P and R branch of the 10.4 μm CO2 laser transitions. The relative optical broadening coefficients were determined from 300 to 650 K.


Conclusions: We have established a whole tissue model for osteoarthritis comprising both cartilage and bone, which is highly responsive to both catabolic and anabolic stimulation. This model responded both anabolic and catabolic to PTH treatment, demonstrating the importance of cell-cell communication. The dual effect on cartilage may be divided in direct and indirect effects from PTH on bone and cartilage, which had not been possible to detect in a single-tissue model system. This model may be useful for testing potential disease-modifying osteoarthritis drugs (DMOADs) interfering with more than one aspect of the pathological situation. Furthermore, it presents a unique opportunity for investigating the role of osteoclast-, osteoblastand chondrocyte-interactions in the pathogenesis of OA and other joint degenerative diseases.


Capitalism has an inherent conflict between its need to raise productivity and its need to control workers and ideas. Direct control over scientists and social theorists and their proletarianisation tends to reduce their ability to come up with new ideas. Furthermore, capital prefers not to bear the cost of fundamental research. On the other hand, it does not want the public sector to grow and demand higher taxes. The effect has been increased marketisation, short-term type research, and increased irrationalism. The right to be confused is the Orwellian result for the time being together with a small band of genuine intellectuals and self-sacrificing workers.


Abstract In this research, we study the privacy and security capabilities provided by telehealth devices. Our aim is to evaluate how vulnerable these popular devices are in the presence of malicious cyber attackers. As older adults increasingly rely on telehealth devices, it is crucial that cybersecurity aspects of these devices are clearly communicated to them. Moreover, older adults frequently lack the technical expertise to evaluate the security and privacy capabilities of the devices. The lack of control over telehealth devices is a major concern for older adults. Older adults view certain limitations within these devices as decreasing their privacy and security. These limitations include the lack of control over accepting calls, taking screenshots, and assigning access privileges. For large scale adaptation of telehealth devices by older adults, it is crucial that these devices not only satisfy their intended purpose but also exhibit user friendly features and strong security and privacy capabilities. Modeling cyber threats against telehealth devices is not studied sufficiently . Malicious actors may compromise telehealth devices and create further threats to security and privacy of the users. In this research, we studied the cyber threats against telehealth devices. We built a threat model that ranks cyber threats based on their impact. We investigated how the operating system of popular devices supports access control. We found that none of the current technologies support location-based access control. We claim that this represents a major limitation and that supporting location-based access control is necessary to ensure users' privacy in their own home.


Six years into NYSERDA's Multifamily Performance Program - New Construction component, Program staff decided to make a philosophical shift in the way the reviews were being performed: to stop being coaches and start being umpires, thereby allowing the energy modelers to be the experts of their own models. The reviewers now focus their efforts in identifying outliers in project-level energy intensity by end use and in measure-level savings, based on a detailed project description, model outputs, and a historic database of over 200 projects previously brought through the Program. The modelers are then tasked with determining the causes of these outliers, and either resolve them or explain why they are justified. While this new approach works well for expert energy modelers, due to the recent growth and relative youth of the energy modeling industry, many modelers are not yet adequately equipped. To address this issue, Program staff developed a guidance document to assist modelers in this process. This paper focuses largely on a summary of that guidance document, which is based on the lessons learned by our reviewers in performing hundreds of energy model reviews. These lessons are applicable to residential and commercial efficiency Programs that require energy modeling. The guidance can be given to energy modelers working in the Programs to assist them in submitting higher quality models, as well as to help expedite any necessary corrections. It can also be used by Program staff to perform model reviews more effectively and efficiently.


Synthesis of 1,2- and 1,4-bis-thiohydantoins and hydantoins employing ethylenediamine and 1,4-diaminobutane as spacers is described. Compounds containing a two carbon bridge were synthesized by alkylation of ethylenediamine with two equivalents of N-t-butyl-α-(p-toluenesulfonyloxy)phenylacetamide 3. The phenyl isothiocyanate adduct of 3 cyclized in refluxing toluene to form 1a. Other isothiocyanate or isocyanate adducts derived from alkylation product 4 required hydrolysis to induce cyclization. Compounds 1b-1f were obtained in this way. Compounds with a four carbon bridge were obtained by reaction of two equivalents of methyl α-bromophenyl acetate and 1,4-diaminobutane to produce N,N'-bis-[(α-phenyl-α-methoxycarbonyl)methyl]butylenediamine 6. The isothiocyanate or isocyanate adducts from 6 cyclized, without hydrolysis, to form compounds 2a-2e.


Support is an important objective scale to evaluate rules in data mining, and setting mini-support raises the effect of mining. Whereas, the itemss existing and occuring frequency are quite different, so keep on one mini-support in data mining process is unreasonable. In this paper, a new algorithm of mining multi-mini-support rules is presented, and the results prove that it is effective and reasonable with application in mushroom database.


Act 1: Allegro The flute player read a poem, then locked his eyes on us, took a deep breath, and burst into notes. Some soft, some loud. At first, nothing unusual. My three daughters, dragged along, were nonplussed. But then the tune changed. The flute took on an ethereal tone. One that none of us had heard before. There was fluttering and flapping sounds, like birds and rain. At one point, the flutist began to hum and play flute at the same time, in harmony. The song took on an aura of its own and when I looked at my kids, they were now rapt.


The present invention provides an occupant protection system for a vehicle, the system has at least one sensor (10), the at least one sensor (10) detects the surroundings of the vehicle (11), the sensor from which generates a signal, the evaluation device has a (12), the evaluation device (12) evaluates the sensor signals, early risk situation that is being approaching according to an algorithm for the early identification of those sensor signals dangerous situation identify, a trigger signal generated in this case, the seat adjustment mechanism having at least one actuator for adjusting the seat (20) has a (22,25,26,27,28), the seat adjustment mechanism (22,25,26,27,28) is a sheet for adaptation (20) seat in the control of the first speed and the trigger signal for the comfort adjustment (20) Have a higher rate of 2. The present invention also provides a method for operating an occupant protection system for a vehicle as well.


The subject of the submitted thesis: "Financial mathematics utilization in economic routine" is to present the utilization of financial mathematics in economic. The first part is concentrated on basic coherence in section of financial mathematics. The second part is about options analysis of consumer credit. The third part consists of creating a calculator in Microsoft Excel for consumer credit.


In this thesis we concentrate on the trade cycle in the nineteenth century developed nations especially Great Britain. We first discuss the evidence for and observations on the trade cycle, together with the major theories and opinions of economists. We conclude that no existing trade cycle model explains fully the qualitative features of the trade cycle. This failure particularly applies to the phenomenon of the "crash".


The directions of improving of the educational environment of the modern research university from the standpoint of effective preparation of graduates, who are capable to generate the new knowledge, first of all in interdisciplinary spheres, are considered.


Introduction:

Coronavirus disease 19 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). With the ongoing pandemic, it is observed that patients with COVID-19 infections are at increased risk of acquiring secondary bacterial and fungal infections. COVID-19 associated pulmonary aspergillosis (CAPA) is a new entity and is associated with high morbidity and mortality. COVID-19 is a pro-inflammatory and immunosuppressive disease, provoking fungal infections, especially by Aspergillus species.
Case Presentation:

We describe a case of critically ill COVID-19 female patient. During her hospital course, she was intubated managed as ARDS and started on empiric antibiotics along with intravenous remdesivir. Clinically she improved and was extubated. Her chest x-ray few days after admission showed multiple cavities. However, 3days post extubation she deteriorated, with worsening hypoxia and pneumothorax and multiple cavitary lesions on HRCT of the chest. Her tracheal cultures showed aspergillus flavus with rising serum galactomannan and beta D-glucan. She was diagnosed with coronavirus disease (COVID-19) associated pulmonary aspergillus (CAPA) infection and acute respiratory distress syndrome (ARDS). Despite optimal and standard treatment, she couldn't make recovery. Interestingly, she had no predisposing risk factor for pulmonary aspergillosis such as chronic lung disease, diabetes or use of immunosuppressant such as tocilizumab.
Conclusion:

CAPA is an emerging entity with a worse prognosis. Worsening hypoxia and failure to improve can be an early sign for underlying pulmonary aspergillosis. Early identification and treatment can improve survival and outcomes in critically ill COVID-19 patients.


The embodiment of the invention discloses a high-refresher-rate waveform synthesizer used for improving the waveform refresh rate WRR through shortening Tmap, improving the capacity of a digital oscilloscope to grab waveform details and optimizing performances of the digital oscilloscope. The high-refresher-rate waveform synthesizer disclosed by the embodiment of the invention comprises a data distribution module, a storage module, a synthesizing module and a data integrating module, wherein the storage module is composed of n storage sub-modules; the synthesizing module is composed of n synthesizing sub-modules; the n storage sub-modules correspond to the n synthesizing sub-modules and are connected in parallel; the storage sub-modules are used for storing waveform data; the synthesizing sub-modules are used for synthesizing collected data and the waveform data and writing obtained fresh waveform data into the corresponding storage sub-modules; the waveform data are read from the corresponding storage sub-modules. Furthermore, the embodiment of the invention provides a high-refresher-rate oscilloscope.


High-density information storage by means of magnetic holography is demonstrated by using amorphous TbFe thin films as a magnetic hologram medium. The object beam, which emerges from a two-dimensional information pattern (in most cases 35 mm photographic films), is focused on TbFe film by a lens using the spatial Fourier-transform pattern. A magnetic hologram, that is, a magnetic domain pattern corresponding to the interference pattern of the object beam and the reference beam, is established on the TbFe film by thermo-magnetic writing. A Q-switched ruby laser (of peak light power=0.6MW and light pulse durations30 ns) was used as the writing light source. An illuminated spot, from 0.2 to 1 mm in diameter, was chosen depending on the size of information. Image reconstruction was done by means of either the Faraday effect (transmitted light) or the polar Kerr effect (reflected light) using a first-order diffracted beam. A He-Ne laser (1 mW or 30 mW) was used for the reconstruction light source. It was confirmed that satisfactory images of not only documents but also picture images can be reconstructed by magnetic holography. The storage density estimated from the preliminary experiment is about 4×103 characters/mm2. Some considerations for improving the reconstructed image quality are also described.


A general study of the effects of the Viking Wars on Anglo-Saxon society is much to be desired. These wars lasted from the last years of the Mercian hegemony to the last months of the life of William the Conqueror. It has been abundantly shown that the English did not catch institutions from the Vikings like a sort of social measles, but common-sense alone suggests that a three hundred years war with little more than one generation's respite must have had consequences. Such a study is far too large for a single paper. What I have sought to do, therefore, is take a single campaign, that culminating in the famous battle of Maldon, which occurred at a moment of intense crisis and to try to set this campaign in a context of the relevant political and military problems of the day, and most of what I have to say relates to the much-dismissed, little studied, but well-evidenced, reign of Æthelred II.


Failure mode and effects analysis (FMEA) is a well-known method in quality management (QM). Until now only less research is done in the application of quality and process improvement with FMEA in the construction industry. FMEA supports the involvement of experts' information, allows engineers to get contextual information to problems and enables to assess possible failure regarding to their relevance. Reasons for that can be found in the common project based manner of building projects, which do not support application of FMEA for improvement projects. Industrialised housebuilding, where project based order fulfilment is combined with process views, starts changing the need for QM-methods in the construction industry. Also because of upcoming use of Building Information Modelling (BIM) concepts a need for appropriate QM-methods is generated, to support the development of usable design standards. In addition it is estimated positive because of the involvement of employees experiences which is a common source of improvement ideas in construction industry. An FMEA case study is applied during an improvement project in an industrialized housebuilding company to test how well it works for this application. The method is further assessed with a use case as well as by findings of interviewed employees.


Sanggabuana coffee is a well known Robusta type coffee that has been cultivated in Karawang for years. This commodity has a high tolerance to diseases and has high caffeine, but in some ways has a cheaper price than Arabica type coffee. However, Sanggabuana coffee has been widely cultivated in Karawang and being the main commodity unique to Karawang. The purpose of this research is to know how high the motivation of the farmer to cultivate Sanggabuana coffee and the connection to the farmer motivation on the social-economic factor of cultivating Sanggabuana coffee. This research will be conducted in Karawang district (Case Study of Mekarbuana village, Tegalwaru sub-district) West Java, Indonesia, Using Primer dan secondary data set. Primer data gathered by direct interview to the farmer or selected respondents as a sample. Generally, respondents consist of the producer or Sanggabuana coffee farmer. Secondary data obtained from the department of agriculture in Karawang district, local agencies, and another related department. The sample is selected using Simple Random Sampling (SRS). The analysis method used in this research is Likert's Summated Ratings and Spearman Rank Correlation. High motivation and social-economic that correlated to the level of education, experienced in farming and the number of family dependent possessed by the farmer as the result of this research.
Keywords: Motivation, Sanggabuana coffee, Correlation.


An atomic beam type polarized proton and deuteron source was constructed at IPCR and installed on the INS SF cyclotron. The polarized beams were axially injected and accelerated in an energy range of 14–33 MeV. For protons the beam intensities are 7.5 μA at the source and 30 nA on the target. For deuterons the beam intensities are 10 μA at the source and 50 nA on the target. The vector polarizations are 50‐75% for protons and 40‐50% for deuterons.


The aim of this research was to analyze the social adjustment (prosocial and antisocial behaviors) of 86 young offenders -between 13 and 21 years of age- attending a correctional school of a socioeducative institute in Cordoba, Argentina. A descriptive/correlational design was used for the analysis. The results show that young offenders have -with regard to the variables measuring prosocial behavior- low levels of empathy and respect and high levels of sociability and leadership. What concerns antisocial behavior, the levels reached for aggression, withdrawal and isolation are high. On the other hand, the collective perception in school of a prosocial atmosphere is low. The correlational analysis indicates significant relationships between prosocial behavior of young offenders, their perception of prosocial behavior among peers in the classroom, and the school prosocial atmosphere. This means that young offenders, who perceive a higher prosocial atmosphere in school, should be more prosocial and vice versa. Therefore, it is considered that the implementation of educational programs design to promote an improvement in the prosocial atmosphere of the classroom, could also contribute to strengthen prosocial behavior in young offenders attending school, thus achieving a better adjustment to their social environment.


Expert systems can be applied to solve complex problems in different areas of knowledge. It have been used by specialists to help diagnose problems in areas such as medicine and engineering. More recently techniques from computational intelligence area, such as neural networks and fuzzy logic were used to build expert systems. These systems can learn from examples provided by problems solved in the past. The success of the expert system depends on how good the model is defined. This paper presents the modeling of an expert system used to classify the internal combustion diesel about the level of corrosion of its metal parts on a three-level scale. The system bases its decision on the results of used lubricating oil analysis. It uses a neuro-fuzzy model, called ANFIS, trained from past diagnoses performed by specialists. The paper discusses how important parameters of the system were defined, such as which variables obtained from the analysis of the oil should be used, the number of training epochs and the number of membership functions used to map the inputs.


The construction of artificial beds for the propagation of the alkali bee ( Nomia melanderi Ckll.) was achieved by duplicating the texture, moisture, and alkalinity of the native soils in which the bee was found. Pits, up to 60 by 60 feet in outside dimension, were excavated 3 feet deep and lined with polyethylene. Two to four inches of gravel were added to the polyethylene and the pits backfilled with soil consisting of less than 7% clay-size particles. Salt was rotovated into the upper level of the bed to effect soil dispersion and reduced water loss. Tubes were led through the soil to the gravel layer as a method of introducing the necessary moisture, and transplants were made into the bed to serve as the nucleus of the new colony. Burrowing populations in excess of 250 per square foot were recorded from a 2-year-old bed, which represents an 8-fold increase in population density over the best natural site in Oregon.


The terms renormalization and renormalization group are explained by reference to various physical systems. The extension of renormalization group to turbulence is then discussed; first as a comprehensive review and second concentrating on the technical details of a few selected approaches. We conclude with a discussion of the relevance and application of renormalization group to turbulence modelling.


Abstract—One of the advantages of H264/AVC videocoding standard is its new algorithms in intra codingmode, but making decision among all these predictionmodes needs some complex computation so it makes abottleneck in implementation of a real-time video codec.In this paper a new and simple method for intraprediction mode decision has been proposed and alsoimplemented on a DM648 TI DSP. Experimental resultsillustrate the proposed algorithm efficiency in codingprocedure speed versus neglectable PSNR and bit ratedegradation.


Jeffrey S. McGuirk received his BSEE degree in 1995 from the United States Air Force Academy (USAFA) in Colorado Springs, CO, and an MSEE degree from Iowa State University in 1996. From 19972000, he was with the Air Force Research Laboratory at Eglin Air Force Base where he designed fuzes for weapons. From 2000-2003, he was with the Air Force Operational Test and Evaluation Center where he directed tests on satellite communication systems. He earned his PhD from the Air Force Institute of Technology in 2009 and again served in the Air Force Research Laboratory from 2009-2012 working on exotic materials. Since 2012, he has been a member of the faculty at USAFA in the Department of Electrical and Computer Engineering.


Recent advances in semantic web technologies now provide the methodology for efficient and adaptable deployment of ontology support to biomedical applications for data annotation and integration.


DOE funding was used to investigate the role of the phosphotransferase system (PTS) in the symbiotic, nodulating bacterium Sinorhizobium meliloti. This system is well studied in several bacterial species. However, it's organization and function in S. meliloti is substantially different than in the those other, well-studied bacteria. The S. meliloti PTS, through our DOE-funded work, has become a model for how this important signal transduction system works in the a-proteobacteria. We have found that the PTS is relatively simple, used for only signal transduction and not transport, and is involved in regulation of carbon metabolism in response to carbon availability and nitrogen availability.


Self-harm and suicide are serious health concerns facing contemporary society, to the extent that some have even declared both to be at epidemic levels. The decision to mainstream mental health into generalist health services, has meant that many health professionals are being required to treat self-harm, despite never having received any specific knowledge or training about it, and whilst potentially harbouring negative attitudes towards the behaviour. The study reported here developed a 51-item Self-harm Survey, to assess whether CAMHS medical and nursing staff (generalist health professionals) differed from allied health and support service employees in their general knowledge, opinions and understandings, and workplace experiences relating to self-harm, as well as in their views on the impact social media has on self-harming adolescents. 82 CAMHS participants completed the survey. Results indicated that contrary to the hypothesis, medical and nursing staff were found to have higher general knowledge than allied health and support service staff, providing evidence that current training programs being administered to address the gap in knowledge have been effective. However, it appears from both the qualitative and quantitative analyses that such programs need to be updated to include proactive support skills, especially around the link between self-harm and social media.
Keywords: self-harm, adolescents, clinical attitudes, CAMHS, social media


With the implementation of global green economy,developing green building is encouraged and promoted as the current construction industry trends. The establishing of green building evaluation system is an important to the development of green building. It could be valuable for establishing an evaluation system of China's Green Building with references and basis.


Wind tunnels are an essential tool in vehicle development. To simulate the relative velocity between the vehicle and the ground, wind tunnels are typically equipped with moving ground and boundary layer control systems. For passenger vehicles, wind tunnels with five-belt systems are commonly used as a trade-off between accurate replication of the road conditions and uncertainty of the force measurements. To allow different tyre sizes, the wheel drive units (WDUs) can often be fitted with belts of various widths. Using wider belts, the moving ground simulation area increases at the negative cost of larger parasitic lift forces, caused by the connection between the WDUs and the balance.In this work, a crossover SUV was tested with 280 and 360mm wide belts, capturing forces, surface pressures and flow fields. For further insights, numerical simulations were also used. It was found that the belt width can substantially alter the flow field, mainly locally around the wheels but also away from the belts. The drag coefficient increased by approximately 0.010 CD for the narrow belts, mainly due to differences in the vortex structures downstream of the front wheels, resulting in larger low-energy regions for the narrow belts. Numerical simulations showed that the change in vortex structures was caused by leakage flows from the gaps between the WDUs and the stationary floor. Comparing two rim designs, it was found that the belt width did not only affect the absolute force measurements but also the drag delta between them.Although the parasitic lift forces increase with the wider belts, a correction is necessary regardless. Hence, given the fact that the interfering leakage flows are further away from the tyres with the wider belts, they should be the preferred choice, allowing more accurate investigations of wheel aerodynamics.


Proteins are amphiphilic molecules with affinity to material surfaces,thus are easily adsorbed on material surfaces and cause biofouling.Nonfouling surfaces are widely used in applications,such as biomedical devices,boat coatings and biosensors etc.Nonfouling mechanism of polymer materials and recent research progress of protein-resistant polymer preparation and surface modification are reviewed.


Based on the large-deformation theory of continuum mechanics,a novel method for describing the large-deformation constitutive relations of geomaterials based on compression test was proposed using total Lagrangian description technique.According to the characteristics of compression test,the transformation formulae of stress tensors and strain tensors between the large-deformation method and the corresponding small-deformation method were firstly derived;and the large-deformation constitutive relation(LDCR) of compression was presented with a general meaning.Then the LDCR equation for the case of a small-deformation hyperbolic model,as well as its corresponding simplified large-deformation hyperbolic model,are obtained.The results of case studies and a parametric analysis show that the proposed large-deformation hyperbolic model can well simulate the constitutive-relations of geomaterials under the large-deformation compression condition.From the viewpoint of both the physical definition and the numerical magnitude,the parameters of hyperbolic models for the large-deformation method and the small-deformation method are different but regularly obey a certain function of variation.


Although activating mutations in the GTPase KRAS are oncogenic and implicated in various malignancies, mutations in KRAS alone are inefficient to transform epithelia. In lung adenocarcinoma, KRAS mutations occur at high frequency and co-segregate with loss of the LKB1 tumor suppressor, a master serine/threonine kinase that phosphorylates and activates multiple AMPK family kinases to control energy homeostasis, cell polarity, and cell:matrix signaling. Despite our current knowledge of LKB1 biology, the complexity of the signaling pathway has precluded investigations into the precise mechanism by which alteration of this kinase contributes to oncogenic transformation and tumor progression in vivo. In the present study, we introduced mutations in Kras and Lkb1 in the genetically tractable organism Drosophila melanogaster. We show that low-level expression of oncogenic Kras (KrasLow) promotes the survival of Lkb1-mutant tissue, eventually leading to a G1 arrest, and concomitant overgrowth of the surrounding tumor microenvironment. Alternatively, high-level expression of oncogenic Kras (KrasHigh) promotes the neoplastic transformation of Lkb1-mutant tissue, leading to autonomous growth and increased cell cycle progression, invasion of mutant tissue into the brain, and the survival and growth of explanted tumor tissue in a wild-type Drosophila host. Interestingly, phosphorylation of the canonical Lkb1 target AMPK is maintained in KrasHigh/Lkb1 neoplastic tissue, but not in KrasLow/Lkb1 tissue. Finally, we analyzed TCGA Pan Lung Cancer data and show that high-level, but not low-level, expression of oncogenic KRAS results in worse overall survival in the context of LKB1 loss. Taken together, these data suggest that increasing levels of oncogenic KRAS, perhaps through mutant KRAS copy gains, are a driving event in the malignant transformation of LKB1-mutant tissue, and that the rewired AMPK signaling axis may offer a potential therapeutic target for patients with this subset of mutations. Citation Format: Briana B. Rackley, Chang-Soo Seong, Melissa Gilbert-Ross. High-level expression of oncogenic KRAS is required to transform LKB1 mutant tissue in vivo [abstract]. In: Proceedings of the AACR Special Conference on Targeting RAS-Driven Cancers; 2018 Dec 9-12; San Diego, CA. Philadelphia (PA): AACR; Mol Cancer Res 2020;18(5_Suppl):Abstract nr B04.


We propose nonparametric time domain statistics to test time series nonlinearity. We show the asymptotic properties of our statistics for an autoregressive process and also discuss the asymptotic results for some kinds of nonlinear processes. Next, we show the power of our statistics for various time series and compare the power of our statistics with that of other well known nonparametric statistics proposed by McLeod and Li [7], Tsay [11] and Hjellvik and Tjφstheim [12] by simulation studies.


This paper discusses the possible impact of the plan of the African government to criminalize the spread of HIV virus through unprotected sex. In South Africa, the Law Commission is circulating a discussion paper on the ¿need for a statutory offense aimed at harmful HIV-related behavior¿. This paper provides an avenue to discuss the concerns over the government¿s plan to criminalize unprotected sex. In the paper, the author viewed that the most important effect of such a statute would not be in the number of actual murderers removed from the streets of Africa, but in the more subtle general impact such a statute would have. The statute might deter those thinking of passing on the virus thus adding to the hysteria around the disease. The author further mentioned other concerns related to the government¿s plan.


Most studies on the family Noctuidae focus on very few species that cause damage to crops; however, there is little information on the biology and ecology of the remaining species of noctuid moths. This work examines the relationship of the larvae of Cucullia calendulae with their main food plant Calendula arvensis. The results showed that the larvae of this species feed on the fruiting bodies, reaching an overall incidence of ca. 30%. In addition, there was a differential distribution of larvae according to their size. Early stages were found in the reproductive structures while latter stages were found on the stems, which should be due to a defensive strategy. Furthermore, from seven characteristics of the patch taken into account, only the height of the plant explained a greater number of larvae per patch.


IL-2 is mainly produced by activated T lymphocyte,act as a natural immune enhancer,and being widely used in clinic.In this study,a roviIL-2 gene was generated by artificial synthesis directly and transformed in E.coli C600.Based on this.We constructed a recombinant oviIL-2 expression vector pPIC9K-roIL2 apply to Pichia pastoris eukaryotic expression system.This studymade a solid foundation for further study of eukaryotic expression and immune mechanismof roviIL-2.


The period, 1944-54, may well come to be known as the "wetback decade" of American immigration history. Our southern border has never been tightly sealed. For several decades prior to I944, illegal entrants numbered, if we measure in terms of Border Patrol arrests, between ten and twelve thousand persons a year. Suddenly, however, in 1944, the figure jumped to 33,681. By 1946, it was Ioo,785; and by I954, it was I,035,282. The year by year fiscal figures are:'


The mechanisms of development of the inflammatory process of the pilosebaceous apparatus in patients with acnе vulgaris are not fully understood, and variations in bacterial colonization are one of the key elements of the inflammatory process. Under the pathological conditions caused by pus-forming cocci which induce the production of proinflammatory cytokines, there is an increase in arginase expression. The capacity for film formation in selected strains was determined by the cultural properties (increased viscosity of the colony biomass) and by differential interference contrast microscopy using a dark field condenser and fluorescence microscopy. Arginase activity (μmole urea/min•mg of protein) was determined spectrophotometrically at 520 nm on saponin-perimabilized lymphocytes of peripheral blood by the rate of urea formation. The cultures of film-forming and planktonic forms of Staphylococcus epidermidis and Staphylococcus aureus were isolated from purulent pustules of 44 patients, aged 18–30. 63.6% of clinical strains of film-forming staphylococci were isolated, out of which 15 strains (53.6%) were S. aureus and 13 strains (46.4%) S. epidermidias. It was found that the arginase activity in patients (film-forming S. aureus) was significantly higher than in practically healthy donors (control) and was equal to 0.262 ± 0.006 and 0.279 ± 0.005 (planktonic form of S. aureus) versus 0.087 ± 0.009 μmole urea / min∙mg of protein in the control. The arginase activity in patients (film-forming S. epidermidis) was significantly higher than in practically healthy donors and was equal to 0.281 ± 0.009 and 0.297 ± 0.006 (planktonic form of S. epidermidis) versus 0.087 ± 0.009 μmol urea / min∙mg of protein in the control. After the auto-vaccine therapy and the administration of the probiotic Lacidofil (Institut Rosell Inc., Canada), enzyme activity decreased significantly in both experiments, however it had not attained control levels. The enzyme activity decreased through the administration of a vaccine, which in turn has an immunomodulating and immunostimulating effect. In addition, comparing the data of the arginase activity after treatment in patients with S. epidermidis, there was a slight decrease in the enzyme activity. This result is probably due to the formed tolerance of the immune system to commensal microorganisms. It was found that all patients had a moderate dysbiosis, which was accompanied by a deficiency of the main normal symbionts of the intestine. After treatment, all patients experienced significant improvementst in the microbiocenosis of the intestine in the direction of normalization of parameters and improvement of the skin condition. Increase in arginase activity in patients with acne vulgaris indicates the competition of this enzyme with NO-synthases for the substrate L-arginine and the alteration of physiological reactions in the organism caused by staphylococci which induce the phagocytic response and the cytokines production of the humoral system.


Following last issue's brief history of the background of Seashore Trolley Museum in Kennebunkport, Maine, Herbert Pence looks at maintenance and operations, and the prospects for the museum's future.


The automotive industry is characterized by the early adoption of technology into their products. In recent years, the automotive industry has developed infotainment systems that encompass navigation, digital media, phone calls, safety and other elements. These infotainment systems are based on componentry similar to smartphones or tablet computers. In contrast to tablet computers, the automotive infotainment systems have followed the typical automotive product development pace, leaving the automotive infotainment systems with outdated hardware and software when compared to the consumer electronic industry. The automotive industry follow a model year cycle while consumer electronics quickly adapt to consumer demand with many releases over a single calendar year. The objective of this thesis is to present a new architecture specific to In-vehicle infotainment systems; providing a faster componentry adoption and faster software updates. Thesis Supervisor: Abel Sanchez Title: Executive Director, Geospatial Data Center 5 Table of


It is shown that shocks propagating in dense molecular regions will lead to a decrease in HCO/sup +/ relative abundance, in agreement with previous results by Iglesias and Silk. The shock enhancement of HCO/sup +/ detected in the supernova remnant IC 443 by Dickenson et al. is due to enhanced ionization in the shocked material. This is the result of the material penetrating the remnant cavity where it becomes exposed to the trapped cosmic rays. A similar enhancement appears to have been detected by Wootten in W28 and is explained by the same model.


The invention discloses a method for fast growth, high yield and high-efficient carbon capture cultivation of grain sorghum and sudan grass. The method comprises the following steps of using the grain sorghum, sorghum halepense, sudan grass and sorghum moench hybrid seeds for propagation; enlarging the planting area; and by fast propagation, high-yield cultivation, multi-time harvest and timely landfill technologies, cradling for 4-6 times a year, and enabling the yield to reach 90-200T/hm . By using the sorghum plant photosynthesis, the CO2 in the atmosphere can be converted into organic compounds to be filled under the ground, therefore, the negative growth in global carbon emission can be achieved, and the atmospheric greenhouse effect can be reduced; the Earth's ice melt can be choked, the sea-level rise can be controlled, the Earth's climate and biodiversity the maintained, and the life time of the humans on the Earth can be prolonged.


Abstract We find all integer solutions to the equation
$x^2+5^a\cdot 13^b\cdot 17^c=y^n$
 with
$a,\,b,\,c\geq 0$
 ,
$n\geq 3$
 ,
$x,\,y>0$
 and
$\gcd (x,\,y)=1$
 . Our proof uses a deep result about primitive divisors of Lucas sequences in combination with elementary number theory and computer search.


Executive dysfunctions and white matter lesions on magnetic resonance imaging have been reported in migraine. The aim of this study was to determine whether any correlation between these 2 variables exists.


I, the undersigned, hereby represent that the entity qualified to audit the annual consolidated financial statements of the LOTOS Group for 2009 was appointed in accordance with the applicable laws and that this entity, as well as the auditors performing the audit, met the conditions necessary to issue an impartial and independent opinion on the audited annual consolidated financial statements, in accordance with the applicable laws and professional standards.


Background: The uncertainties of input parameters in an deterministic structural integrity assessment of pressure vessels may affect the assessment results.This can be improved by performing probability facture mechanics(PFM) analysis.Purpose: This work investigates the effect of uncertainties of load,defect size,fracture toughness and failure criteria on the failure probability of semi-elliptical surface cracks in plates under combined tension and bending.Methods: The correction factor method provided by EPRI is used to estimate the stress intensity factor(SIF).The J-integral values at the deepest point of the surface crack tip are evaluated using the reference stress method and the globe limit load solution developed by Goodall Webster and Lei.PFM analysis is performed with considering the uncertainty of crack size,yield strength and fracture toughness and Monte-Carlo(MC) simulation is used to calculate the failure probability.Results: Failure probability increases with increase of load level,Lr,for all load ratio values considered in this work for a given failure criterion.However,the failure probability based on the elastic-plastic fracture criterion is higher than that based on the linear elastic fracture criterion for a given load lever,Lr.Conclusions: The load level and the failure criteria have significant effect on the failure probability.However,the load ratio makes a little contribution to the failure probability for a given failure criterion.


Cardiac disease is an important cause of premature death in industrialized countries. It is estimated that cardiac disease will emerge as single largest contributor to morbidity in India accounting for nearly one third of total deaths in near future. Cardiotonics are the agents which increase the force of contraction without altering heart rate, which can be used to treat cardiac diseases. Due to life-threatening or severe adverse drug reactions of available cardiotonic, people are seeking alternative therapies that may have maximum beneficial effects with least side effects. The present review focuses on various classes of cardiotonic, their mechanism & major adverse effects as well as better herbal alternate of these available cardiotonics. Many of them were scientifically proved as a cardiotonic. All of the drugs finally increase intra-cellular calcium (Ca 2+ ) level which results into increase in force of contraction. Present review also


Abstract Two experiments were conducted to determine the influence of the method of removing the tibiae and the physical state of the tibiae (wet versus dry) on various bone quality properties in chickens. In Experiment 1, 40 Leghorn hens in each of two trials were killed at oviposition and tibiae were removed either by direct excision (Method 1) or by skinning the drumstick, removing the bone, and boiling it for 10 min (Method 2). In Experiment 2, broilers were fed a control or a cholecalciferol-deficient diet for 28 days, after which the birds were killed and both tibiae were removed by direct excision. Two trials were conducted using 100 broilers in each trial. Tibiae obtained in each experiment were analyzed for bone mineral content, bone density, bone strength, and bone ash either as wet (fresh) or air-dried at room temperature for 3 or 7 days. In Experiment 1, results showed that the method of removing the tibiae did not affect mineral content, density, and strength; whereas values for ash varied with the physical state of tibia and method of removal. It took .67 h to obtain 40 clean tibiae by Method 1 whereas it took 2.7 h by Method 2. Values for mineral content, density, and strength differed for fresh (wet) and air-dried tibiae. When tibiae were dried for 3 or 7 days, mineral content and density were reduced by 25 to 28% (Experiment 2). Bone strength of cholecalciferol-deficient birds increased more than twofold when dried for 3 or 7 days. Bone ash was not affected by physical state of bone. Results indicate that the bone properties, mineral content, density, and strength commonly used to assess bone quality, are influenced by physical state of bone (wet or dry), which should be considered when making decisions about the effect of nutrients on bone status or bone mineralization.


Objective:To study the superiority significance of DFA and DOT in detection chlamydia trachomatis.Methods:386 patients specimens go on detection by DFA and DOT method.And as the detection result of two methods goes on compare and analyses.Results:386 patient specimens were identified by DFA and DOT,the positive rate was 28.2% and 16.32%.Two methods had notable discrepancy(P0.05).Conclusions:Compared with DOT is simple sensitive and suitable for clinical application DFA for detecting chlamydia trachomatis in patient specimens is of clinical significance in early diagnosis.


PRESIDENT posal to decentralize Reagan's sweeping governmental proposal t decentralize gov rnmental responsibilities in our federal system,1 and those proposals that followed it, have indeed raised three fundamental questions. What level of government, the federal or the state, should be responsible for poor people, poorer cities, and poorer states. Already an important consideration today under "old federalism," the difference between the rather extraordinary tax wealth of some states and the relatively anemic resources of others would be an even more important consideration in moving to a more decentralized system of government. Under such a new federalism, one can ask: should the federal government turn back more and more responsibilities to the states in a way that recognizes that some will have heavy responsibilities but only meager resources?


The goal of technology transfer is to improve the livelihoods of rural households and communities. This goal is proposed to be achieved by pilot-testing a sustainable and integrated water and land management strategy in selected districts and provinces that will introduce or expand the use of high-value, water-efficient crop and livestock systems to increase farm household income. Where these new agricultural innovations and/or value-added systems are proven to be effective, then the next step will be to scale-up these innovations to other producer/farmer groups within the current and/or other comparable agro-ecological zones/districts within the country. An additional purpose will be to organize farmer, producer, community and/or self-help groups (especially for rural women) at the community level so they can learn procedures for marketing specific high-value crops and products, as well as in managing their water resources at the community level. The paper discusses the methods and strategies using participatory rural appraisal to evolve a workable model for developing the agricultural sector in two provinces of Afghanistan, namely Balkh and Nangarhar.


Under special circumstances, pressure on the globe resulting from retro-bulbar processes gives a characteristic ophthalmologic picture of retinal grooves or folds. Birch-Hil-schfeld (1920) reported a case of a twenty-year-old woman with a spindle-cell sarcoma arising from the roof of the orbit. The tumour had caused a severe exophthalmos. Ophthalmoscopy showed distinct, fine, bright horizontal striations in the retina, most pronounced in the mac~ilar region, but nevertheless occupying most of the fundus. Lijlzlein (1927) described a case in a man, aged forty-seven, with a mucocele of the frontal sinus which had bulged through the roof of the orbit, displacing the globe out and down. Astigmation had developed, and ophthalmoscopy showed distinct horizontal striations. The retinal vessels showed a normal course and were not involved in the striations. Thirl (1932) described this characteristic picture in his *Atlas der Rontgendiagnostik des Schadelsn and reported four cases. k'iigrlberg ( 1 932) reported a case in a forty-three-year-old women with exophthalmic goitre. There was severe bilateral exophthalmos with palpebral oedema. The retinal grooves described were seen in both fundi. This patient experienced a strange entoptic phenomenon, all objects appearing as if they were horizontally striated. Neither in this case were the retinal vessels involved in the formation of the grooves. The author concluded that the histological changes must be found in the inner layers of the retina, the inner limiting membrane and the nerve fibre layer. TYolter & Jampel studied the histological picture of the retinal grooves and described one case. This was a twenty-year-old woman with an osteosarcoma of the maxilla which had grown into the orbit and displaced the globe out and down. Typical retinal grooves were found, most pronounced between disc and macula. Two different types of grooves could be distinguished in this case: 1) Large folds, involving all the layers of the


Using the Korf equation as the curve model of the dominant tree's height growth,this paper established the single shaped and multi shaped curve models of the site index,then tested and compared them The results showed that:the single shaped curves which established by standard difference adjusted method,proportion method,and dispatch equation method have limited evaluating precision and are relatively difficult to content the demands But those multi shaped curves which established by the three same methods have perfect evaluating precision The improving effect are very remarkable by using the simplex method to optimize the parameter of multi shaped curves After the comparison,the author selected out the highest precise multi shaped curve H=SI×exp〔(4 814 6+24 509 2÷SI)×(20 -c -t -c )〕,c=0 504 6e -0 023 7SI as the curve model of site index,then made the site index table


This paper presents selected results and aspects of the multidisciplinary and interdisciplinary research oriented for the experimental and numerical study of the structural dynamics of a bend-twist coupled full scale section of a wind turbine blade structure.
The main goal of the conducted research is to validate finite element model of the modified wind turbine blade section mounted in the flexible support structure accordingly to the experimental results. Bend-twist coupling was implemented by adding angled unidirectional layers on the suction and pressure side of the blade.
Dynamic test and simulations were performed on a section of a full scale wind turbine blade provided by Vestas Wind Systems A/S. The numerical results are compared to the experimental measurements and the discrepancies are assessed by natural frequency difference and modal assurance criterion. Based on sensitivity analysis, set of model parameters was selected for the model updating process. Design of experiment and response surface method was implemented to find values of model parameters yielding results closest to the experimental. The updated finite element model is producing results more consistent with the measurement outcomes.


MS Two monitoring approaches are described in the American Association for the Study of Liver Diseases/ Infectious Diseases Society of America (AASLD/IDSA) guidelines, and European guidelines have similar recommendations. The traditional monitoring approach includes extensive pretreatment evaluation, on-treatment monitoring of laboratory testing, office visits, and monitoring after treatment to confirm sustained virologic response (SVR) or cure. In late 2019, the AASLD/IDSA guidelines panel released a simplified algorithm designed to pare down the tests needed before treatment and allow for minimal, if any, monitoring during treatment, in addition to checking for cure afterward. This monitoring approach targeted patients infected with hepatitis C virus (HCV) who were seen as uncomplicated or easy to treat, and focused on the pangenotypic treatment regimens of sofosbuvir/velpatasvir (Epclusa, Gilead) and glecaprevir/ pibrentasvir (Mavyret, AbbVie), which are given for 12 and 8 weeks, respectively. The guidelines panel laid out specific criteria for each monitoring approach and separated patients into 2 groups, depending on whether they had cirrhosis. Most patients without cirrhosis could be treated by obtaining simple measurements such as a complete blood count and chemistry profile, determining the liver disease stage using an easily calculated scoring system (eg, the Fibrosis-4 [FIB-4] score), measuring the virus level but not the genotype, and identifying factors for which patients should be excluded from minimal monitoring. One example is active hepatitis B virus infection, which is defined as being hepatitis B surface antigen (HBsAg)-positive. Patients who have been treated previously but failed to achieve cure should probably also be excluded from minimal monitoring, as these patients likely require an intensive approach to understand why treatment failed and to make sure that the second or third course of treatment is successful. Other HCV-infected groups that should be excluded from minimal monitoring include patients also infected with HIV (although I think this group is relatively simple to treat after accounting for drug interactions), women who are pregnant, liver transplant recipients, and patients who also have hepatocellular carcinoma. It should be noted that patients with HCV infection who have cirrhosis have a separate simplified monitoring algorithm, but it requires more evaluation because cirrhosis is a serious medical condition that increases the risk of liver cancer as well as liver decompensation.


Illustration is an objective art form which is strongly based on the relationship between written information and visual imagery for a third-person audience. That is, it is a supportive art for texts, not an art in which pictures stand independently. While most illustrators create illustrations with literal sense, other aspire to illustrate with broader purpose(s) and in media other than print. The former is thus called conventional illustration, the latter gallery illustration. Conventional illustration originated in prehistoric times expressly to convey information and after the invention of writing and then printing became associated with information, as in, say, advertising in the business world. As such, it was for production in publication media (magazines) and space media (newspapers). Then in the early 1980s a new illustration movement started in Germany and the United States, allowing illustrators to work in a more artistic way than before. A similar situation arose in the mid-1990s in Korea with a number of its illustrator` and researchers` efforts to investigate and promote the role of this new illustration called gallery illustration. Now an independent visual culture in Korea, gallery illustration has come to possess a certain zeitgeist as illustrators` personal artistic record of the times.


In recent years hybrid sorghum has been cultivated in an ever-growing area of southern Kweichou Province.The sorghum fly Atherigona soccata Rondani is one of the worst pests of sorghum in China.From 1973 to 1974 its bionomics and controlling measures were studied.In Tu-yan district this insect had seven generations a year.The influences of various environmental factors on its development were observed.For controlling this pest cultural method by regulating the date of sorghum sowing and chemical method by application of Dimethoate were found to be effective.


This paper presents a lightweight but effective mastersender-driven multiple parent approach for online video adaptation and streaming to heterogeneous clients. The proposed design facilitates the cooperation of participating clients for improving the utilization of the spare resources in an overlay. Our design uses standard H.264/AVC video streams. It enables peers to contribute both CPU and bandwidth in a multi-parent fashion, such that no dedicated adaptation server and streaming server is required, although we need a reliable rendezvous point for the video stream originators and the peers in the overlay. We present the live video processing paradigm using metadata followed by the video distribution overview. A brief performance evaluation supporting the design choices is also presented.


The Supreme Court of Arizona has ruled that the Arizona Department of Water Resources (ADWR) had the authority to impose total gallons‐per‐capita‐per‐day (liters‐per‐capita‐per‐day) requirements directly on municipal water providers, rather than only on individual end users.


On 28 June 2011 the United Nations (UN) Security Council in its Resolution 1991 stated that: 'The Government of the Democratic Republic of the Congo bears primary responsibility for security, peacebuilding and development in the country, and [encouraged] the Government of the Democratic Republic of the Congo to remain fully committed to protecting the civilian population through the establishment of professional and sustainable security forces and the rule of law and respect for human rights, to promote non-military solutions as an integral part of the overall solution for reducing the threat posed by Congolese and foreign armed groups and to restore full State authority in the areas freed from armed groups.'


The unique style of nationalization and popularization of literature and art is embodied in Zhou Libo's Great Changes in the Mountain Village.This is the fruitful achievements that he had studied and searched for.Zhou Libo took an active part in the discussion of the masses of the literature and art early in the 1930's.After publication of Chairman Mao's speech at Yan'an Forum on Literature and Art,in theory and practice,he consciously took the road of learning the People's Literature.Meanwhile,he advocated that artists should make good use of Chinese classical heritage of the essence,by the unique artistic vision to form their own distinctive national features in their own works.Zhou Libo had successful experiences and unique theoretical expositions in applying the dialect in his writing and creation.


Introduction: Our understanding of paleoclimate and surface alteration processes, as well as potential past life and habitable environments on other planets depends on the geochemical, mineralogical and visual data we receive from space missions and our ability to interpret these observations based on analog terrestrial processes [1,2]. The Mars 2020 mission landing criteria exclude "special regions" where solid or liquid water may be found within 1 m of the surface from the target regions for planetary protection [3]. Therefore, determination of past life will depend on observing morphological fossils and/or interpreting biosignatures. In order to determine potential relationships among sediment texture and primary mineralogy, bulk chemistry, depositional setting, alteration history, and microbial influences, we have previously investigated the physical (surface area, grain size, SEM morphology), chemical and mineralogical properties of a large collection of glacio-fluvial sediments, drift/till deposits and permafrost soils [4,5]. Our analyses of sediment from Antarctica, Iceland and Norway successfully linked grain surface area to depositional setting and thus paleoclimate [4]. However, isolating the effects of microbial influences on surface alteration is difficult, as all samples have been exposed to some microbial alteration, and chemical and mineralogical biosignatures are often overshadowed by original bedrock characteristics. Therefore, we are conducting controlled biotic and abiotic weathering experiments to compare alteration features and identify potential inorganic biosignatures (mineral, morphologic, and inorganic chemical traces of microbial activity) in analog sediments. Here we report our first results from biotic and abiotic cold-temperature (12oC) weathering experiments on Icelandic glacio-fluvial sediments to identify potential inorganic biosignatures that could also be observed on Mars (Figure 1). Sample Collection, Preparation and Characterization: Fine-grained glacio-fluvial sediments were collected from the proglacial stream after the eruption of Eyjafjallajökull volcano in Ásólfsskáli, South Iceland. The sediment was wet sieved to obtain the <63μm (mud) fraction, and treated with glacial acetic acid and H2O2 to remove carbonate and organic fractions, respectively [5,6]. Freeze-dried samples were analyzed with a Rigaku Ultima IV XRD with Cu radiation source and graphite monochromator, using the Bragg-Brentano method (2-70o 2θ angle interval). The chemistry of the silicate mud was analyzed with ICPOES. Sediment surface area was determined with the BET nitrogen adsorption method and grain size was determined with laser particle size analysis (LPSA).


Emerging deep neural network (DNN) applications require high-performance multi-core hardware acceleration with large data bursts. Classical network-on-chips (NoCs) use serial packet-based protocols suffering from significant protocol translation overheads towards the endpoints. This paper proposes PATRONoC, an open-source fully AXI-compliant NoC fabric to better address the specific needs of multi-core DNN computing platforms. Evaluation of PATRONoC in a 2D-mesh topology shows 34 % higher area efficiency compared to a state-of-the-art classical NoC at 1 GHz. PATRONoC's throughput outperforms a baseline NoC by 2-8× on uniform random traffic and provides a high aggregated throughput of up to 350 GiB/s on synthetic and DNN workload traffic.


This study investigated the intrinsic connections of a key‐structure of the endogenous pain inhibitory system, the pedunculopontine tegmental nucleus (PPTN), in post‐ictal antinociceptive process through synaptic inactivation of the PPTN with cobalt chloride. Male Wistar rats (n = 6 or 7 per group), weighing 250–280 g, had the tail‐flick baseline recorded and were submitted to a stereotaxic surgery for the introduction of a guide‐cannula aiming at the PPTN. After 5 days of postoperative recovery, cobalt chloride (1 mM/0.2 µL) or physiological saline (0.2 µL) were microinjected into the PPTN and after 5 min, the tail‐withdrawal latency was measured again at 0, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 110, and 120 min after seizures evoked by intraperitoneal injection of pentylenetetrazole (64 mg/kg). The synaptic inactivation of PPTN decreased the post‐ictal antinociceptive phenomenon, suggesting the involvement of PPTN intrinsic connections in the modulation of pain, during tonic‐clonic seizures. These results showed that the PPTN may be crucially involved in the neural network that organizes the post‐ictal analgesia. Synapse 68:369–377, 2014. © 2014 Wiley Periodicals, Inc.


OBJECTIVE:To review the new advancements of chemotherapy to colorectal cancer(CRC).METHOD:Retrieve keywords such as " colorectal cancer or colorectal carcinoma and chemotherapy " on PubMed,CNKI and ASCO proceedings from 2005-01to 2012-06.Totally 303English articles and 78Chinese articles were obtained.Inclusion criteria:1) colorectal neoplasms;2) drug therapy;3) large clinical test with random contrast;4) eliminate clinical test with single centrality and small specimen.According to the inclusion criteria,31articles were finaly analyzed.RESULTS:CRC treatments such as adjuvant,new adjuvant chemotherapy,metastatic neoplasm chemotherapy and targeted therapy all derived significant advancement.By appearance of new chemo drugs,Oxaliplatin,Fluorouracil,CPT-11,Xeloda and molecular targeted drugs like Cetuximab,Bevacizumab combined proposal have significant improved survival period and corresponding rates,and adverse reaction decreased.CONCLUSION:CRC chemotherapy is developed to standardization and individualization,which will give the patients more clinical benefit.


____________________________________________________________ Radius [cm] Fluence of fast hadrons [cm-2] Dose [KGy] ____________________________________________________________ 4 1.6x1016 4200 11 2.3x1015 940 22 8.0x1014 350 75 1.5x1014 35 115 1.0x1014 9.3 ____________________________________________________________ Hadron fluence and radiation dose in different radial layers of the CMS tracker for an integrated luminosity of 2500fb . (CERN-TH/2002-078)


The central character of this monumental book is Jai Ram Reddy, the most outstanding political figure of post-war Fiji, the leading Fiji political thinker of his time, and the most brilliant lawyer of his generation — and a charismatic campaigner. As an intellectual who engaged deeply in politics in a society where ideas were always displaced by narrow ethnic issues, he was a complex personality. Nevertheless, he left a major mark on the people and politics of Fiji, yet was haunted by a deep sense of rejection. Lal's book, probing the life and ideas of Reddy, is also inevitably a book about the politics of Fiji, at critical moments, in its political and economic context, tormented by racial politics. It covers a period of over a century, from the arrival from India of Reddy's paternal grandfather in 1903 as an indentured labourer, until 2008, when he went to settle in New Zealand after he finished, with great distinction, a five-year spell as a judge of an international court in Arusha to try perpetrators of the Rwanda genocide. This panoramic view of Fiji's history begins with the migration of Indian indentured labour, the social and economic development of Fiji in the colonial period, the politics of independence, the emerging political order drawing its inspiration from the fundamentals of the colonial system, the crisis of 1987 with the political victory of the Coalition of progressive Fijians and Indo-Fijians, breaking from the mould of ethnic and chiefly politics, to a series of coups which have left the people bewildered and the country, above all the indigenous Fijians, divided. Lal's approach, weaving the personal and the national, using the career of Reddy to understand Fiji's history, works well because of his profound knowledge Fiji history, illustrated by his magisterial Broken Waves: a history of the Fiji Islands in the 20th century (1992). The book consists of two elements: the historical account interpreted by Lal and reproduction of key speeches by Reddy. Although Lal is adroit at capturing the changing circumstances and moods of the country, Reddy's speeches provide an excellent guide to his thinking, his reaction to challenges facing the country and his community, shifting gradually to a vision of a non-racial Fiji, his intellect and integrity, and hints of Reddy the teacher. In the Eye of the Storm is woven around various, connected themes: South Pacific colonial history, Indian migration, race relations in colonial and post colonial periods, the hold of ethnicity on politics and the politics of ethnicity, the appeal and force of 'indigeneity', and the conversion of inter-racial conflict to intra-community conflict. Fiji was unusual, on independence, in preserving and consolidating colonial arrangements, inherently in contradiction with democracy and rights, and obstructing nation building. Because of the racial division of occupation, politics and representation, Reddy spent most of his political career competing with politicians of his own community. Lal notes that the 'Pandering to the narrow communal interests of your own people, the more strident the rhetoric the better, was the sure, tried route to political power' — true of both indigenous Fijians and Indians. The book notes the remarkable transformation of Reddy from an 'Indian' politician (effectively condemned by constitutional arrangements as a perpetual 'Leader of the Opposition') into a truly national leader, respected and admired by all communities. Locked into the straitjacket of ethnic politics by the constitution, he saw the futility of racially driven politics, which obscured the issues of development and integration. The narrowness and meanness of ethnic politics were a constant affront to his integrity and vision, which informed his ideas of constitutional reform. The formation, politics and aftermath of the Labour–NFP Coalition showed the constellation of social forces that had the prospect of generating a new politics, but also the social, ethnic, class and regional complexity of Fiji, the alliance of disparate interests from across communities challenged by those with vested interests in divisive politics, and not infrequently each of the major ethnic communities torn by its internal differences. Reddy's own position shifted gradually and subtly from advocacy of racial partnership and 'power sharing' to a non-racial


The information presented in the current work on the occurrence of root-knot nematodes (Meloidogyne spp.) in Greece was extracted from the literature and unpublished studies conducted by the authors. The species M. javanica, M. incognita, M. arenaria, M. hapla, M. artiellia and M. exigua had been reported during the period 1963-1994 to occur on various host plants and species identification was based on morphological characters. Since 1996, 52 isolates from Crete and 9 isolates from the mainland of Greece were identified using molecular and/or biochemical markers. The species found were M. javanica, M. incognita and M. arenaria. Twenty-six of these isolates were identified as M. javanica (19 isolates), M. incognita (5 isolates) and M. arenaria (2 isolates) on the basis of the esterase phenotypes. All M.javanica isolates exhibited the typical J3 phenotype except one from Crete, which exhibited the J2 phenotype. The M. incognita and M. arenaria isolates revealed the 11 and A2 phenotypes, respectively. Finally, the infestation of potato tubers by a M. javanica isolate (phenotype J3) is reported for the first time in Greece.


Light industry is one of leading branches of Uzbekistan and has centuries-old traditions on processing of cotton fiber, silk, wool, skin. The share of this sector accounts for about 14 % of produced in the Republic of industrial products, therefore the development of this sector of economy is of great importance for the General welfare of the country. In the present article questions of reforming of branches of light industry by control system modernization are taken up; the base, allowing adjusting mechanisms of corporate governance is presented legislative-normative base, some data on functioning opened joint-stock companies and the State joint stock company "Uzyengilsanoat" are provided. Emphasized the need for good corporate governance in joint stock companies by attracting foreign investment, and in this regard the conditions, which can serve as attractive factors for foreign investments in the light industry. Among them are the state support of the industry, the benefits provided to develop the industry, the availability of a wealth of raw materials resources, development of market infrastructure and etc.


The 15 papers in this special section present new tools, techniques, applications, approaches, and surveys related to various aspects of reliability, and risk analysis and management.


Graphic design is used to transmit information and present creativity through a two-dimensional media,and to extend the meaning of information in a limited space. In graphic design,the most easily overlooked visual element is blank space,the neglect of which is also the cause of the failure of many graphic design works. Blank space could be weak text,graphics or color,playing a role of setting off the motif in the entire page background. Its vitality is in contrast to and unified with the graphics simultaneously.


Impelled by drastic competition of steel market,steel enterprises have been looking for new technology and techniques to improve quality of products,decrease cost of production and promote competitive capability in the market.Technology of Bar and Wire Rod endless welding rolling could eliminate some traditional rolling techniques,such as intervals between billets,cutting heads and rears of rolling products,etc.Thus,this technique has attracted more and more attention of steel enterprises from home and abroad in recent years.This paper presents concept of bar and wire rod endless welding rolling,compares characteristics of traditional rolling techniques with those of bar and wire endless welding rolling and analyzes potential economic benefits of technology of bar and wire endless welding rolling.


G-22 MAPPING OF UPPER JURASSIC SANDSTONE IN THE BORG NORTH AREA USING ELASTIC INVERSION J. HELGESEN 1 A. KARLSEN 2 O. RUNDE 1 and J. STEINDL 1 Summary 1 The Upper Jurassic Draupne reservoir sandstone in the Borg area is difficult to distinguish from the Draupne shale using seismic data mainly due to the small thickness of the sand and the wide variability of acoustic impedance in the shale. Through careful processing of the seismic data layer-based elastic inversion of partial stacks and 3D visualisation we were able to identify and map these sandstones using the estimated Poisson's ratio and


A method of attaching a metal surface (202) on a support (206) (100) is provided, the method (100) comprising: forming a first polymer layer (204) over the metal surface (202) (110); Forming a second polymer layer (208) over a surface (222) of the support (206) (120); (And in physical contacting of the first polymer layer (204) with the second polymer layer (208), so that at least one of an interpenetrating polymer structure and is distributed polymer structure (214) between the first polymer layer (204) and the second polymer layer is formed 208) (130).


Abstract: The objective of this study is to investigate the implementation of mind mapping in teaching writing narrative text. This study is conducted at the eleventh grade students of social class of Madrasah Aliyah Negeri 13 Jakarta. This study uses qualitative research design to find the answer of the objectives of the research. The data is collected by classroom observation, the teacher's and the students' interview, and students' works. All the data are collected, classified, and analyzed. The data which could represent to answer the objective of the research are taken as the example. The example data are used as proves of the research finding. The research finding of this study shows that mind mapping has good influences to the students writing skill. It equips the students with clear guideline to write because it allows students think freely and creatively. The students understand the text organization of narrative, the tense in writing narrative, and how to determine the sequence of the story based on the mapping and key words provided. Key words : mind mapping, teaching writing, narrative text, qualitative


Wavelet transfer(WT) is a powerful technique in signal separation and can improve the signal to noise ratio by separating the random noise and useful signal. The method in the paper introduced the concepts of binary wavelet transfer and Lipschitz exponent. According to the performance of maximum module between the noise and signal, the appropriate filter was realized. The simulation data demonstrated the feasibility of the method.


The publication of Meir Dan-Cohen's collected essays provides a welcome opportunity to reflect on a career of innovative and influential scholarship in criminal law and legal philosophy. By addressing his works collectively I hope to unearth creative tensions between arguments framed at different times and in response to different concerns, tensions not visible when the arguments are taken one at a time. Part I of this Review discusses the essays Harmful Thoughts and Defending Dignity; Part II centers on Decision Rules and Conduct Rules: On Acoustic Separation in Criminal Law and Responsibility and the Boundaries of the Self; Part III turns to In Defense of Defiance and Conceptions of Choice and Conceptions of Autonomy. Each pair of essays reveals a tension within Dan-Cohen's ideas surrounding the purposes and limits of the criminal law and the meaning and value of human autonomy. I will attempt through an exploration of his ideas to sketch some of my own, ideas which preserve and synthesize his many insights while avoiding many of their conflicting implications. I only hope my discussion will be helpful and not merely harmless.


To look for a new kind of piperazine with high activity,according to the amalgamation principle on pharmacology,6 piperazine derivtives which were not reported on documents were designed and synthesized.Piperazine as the raw material with substituted benzyl chloride to give 1-substituted phenyl piperazine 1,and then 1-substituted phenyl piperazine reaction with 2-chloroethyl benzoate to get the compound(3a-f).The results indicated that the synthetic method of intermediate 1 was improved,with mixed solvents of isopropanol and distilled water under easier condition to provide more than 70% of high yields.All of compounds were confirmed by IR,1HNMR,MS and elemental analysis,showing the reliability of this new synthetic method.


In power electronics circuits, the stray inductance of a bus bar between a DC capacitor and power devices may affect an overvoltage and influence the switching losses under high-speed switching operation. Therefore, it is necessary to design the wiring structure by considering the stray inductance of the bus bar. An inductance map is proposed to clarify the relationship between wiring structure and stray inductance of a DC-side bus bar. The inductance map is drawn using a partial inductance calculation method. In addition, the design procedure of the wiring structure with consideration the stray inductance of the bus bar is shown using the inductance map. This paper makes four types of DC-side bus bars for a buck chopper circuit, and the over voltages under the turn-off switching are discussed by the experiments. The experimental results rated at 500 V, and 70 A for a buck chopper circuit using SiC-MOSFET and SiC-SBD confirm the validity of the design procedure.