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The data today was disappointing, and it does throw into question whether or not this drug is better than the SOC. It's far from dead though. Dr. Missling is going to have to earn every penny of his paycheck to get 2-73 back on track. Potential for this drug is broad, so he and his team have to focus and come up with a way to get it to market with and/or without AD. Don't fool yourself - the game has now gotten tougher.
It is surprising that so many people (investors included) misunderstand the AD part of this investment. AVXL 2-73 is not about curing AD and it is not about reversing memory loss. It is about coming up with something that is safe and just a little more effective than what is currently out there. If that means sometimes stopping progression and/or giving a small percentage of people some cognitive reversal while safe that is all that is needed. AD has a terribly deficient SOC today and the market is screaming for something better - even if just a little better.
As for the market - it doesn't matter much. It's a huge market regardless of how effective the drug is again assuming safe. This is a game of moving the needle and not curing a disease. AD has no effective treatment today and so an improvement in SOC is almost as good as a breakthrough cure. Millions will take a safe drug that gives them say a 1 in 3 chance of slowing the disease and say a 1 in 5 chance of getting some memory back. AVXL has a golden opportunity to make it big with a safe solution and a just decent efficacy profile.
Efficacy is not the driver. That's a mistake most people make. The standard of care (SOC) is exceptionally low for AD, and so the FDA will be flexible with a drug that has even a slightly better efficacy than the SOC but with a solid safety profile. For this particular disease, and with a goal to get this drug approved, the safety profile is equally if not more important.
jq has no juice whatsoever. Obviously nobody owning or selling a share listens to him.
I'll explain this one clearly to you. Smart clinical stage companies want to avoid a placebo arm until phase III because they can. The game with any company like this is to continue to move forward by doing what is needed. Placebo (and double blind) is needed for phase III. However we need to get approval to get to phase III first. Cart before the horse. That's how it works.
What is the AE that causes your brain disorder?
They switched the topics for today's poster. Based on the release it was originally supposed to talk about MMSE but they decided to focus on safety. So today was about safety with some sprinkling in of efficacy. In my eyes w/respect to efficacy it really doesn't say much which based on the poster title is to be expected. They need to back this up with solid data on Wednesday.
No. While it would be disappointing we have plenty to look forward to here. SOC is incredibly low in this disease so what we already have is better than anything else - and it's all about improving SOC. But let's wait until Wednesday before we make any more assumptions.
I know your MO is to put a negative spin on it. Fact is there is no solid conclusion to draw from this one way or the other because we have Wednesday's data to come. It is just annoying to me that they would do this because it invites questions.
Yes but why include MMSE at all then in this poster?
Mostly yes, what I don't like it that they reiterated 5-week MMSE improvements and didn't mention anything about 31-week MMSE. They should have either removed the 5-week or included the 31-week because it makes one think that there is no sig improvement on the 31-week data.
chemist - today's poster appeared to be positive. Why though did they highlight 5-week MMSE improvement which we already knew? I was hoping for some documentation on 5 week vs. 31 week improvement. Or is this something we are looking to see in Wednesday's poster?
I happened to have followed that very closely. ARNA was one of three different companies trying to get to market with a diet drug. There had been no new diet drugs for years. All three companies had drugs that showed questionable efficacy. While it was impressive to get the drug approved it was also well understood that the market was going to be choppy at best because the drug was proven to only have limited effectiveness. That and there are so many other ways to lose weight. That is why the stock topped out.
AVXL situation is completely different. If this drug gets to market with the type of profile it is currently showing for AD the stock will explode. Millions are clamouring for an AD drug that can improve their lives as there is nothing else out there.
I think you are pointing out that Adam Feuerstein runs a shady operation. There is no doubt that he colludes with funds/money managers. I still do not know why the SEC hasn't investigated his practices.
Wow, that's a huge rate.
Is it true that fake posters (i.e jq_dt, etc.) get paid a quarter dollar per post? I'm just thinking if he hits 100 boards a day and posts 100 times per board he's got $2,500. Sounds like a lot but you can get an algorithm to do something like that.
25c per post? Man, the way he posts he must be rich.
My crystal ball broke last week. Never seemed to work well anyway.
Well since BIIB is at $250/share with a $55B market cap, $500/share would double that market cap to $110B. $560/share would be even more.
There is not one startup company today that doesn't go through hundreds of variations of how to build a business - including weird and strange things that may you scratch your head. The bottom line is to forget about anything in the past because it is irrelevant. Base your decisions on how you feel about present and future.


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How2 ... join the Linux movementSubmitted by srlinuxx on Monday 22nd of September 2008 06:51:23 PM Filed under
stuff.co.nz: The Linux movement has taken off and Dave Thompson goes undercover to find out how to join. Every week we get someone asking about Linux what is it, why is it and should I do it? The answer is complicated.
Ohio LinuxFest 2008 PreviewSubmitted by srlinuxx on Monday 22nd of September 2008 06:49:43 PM Filed under
softpedia.com: The Greater Columbus Convention Center will host this year's annual Ohio LinuxFest, which will take place on October 10-11. Now at its sixth edition, the Ohio LinuxFest will include a large expo and popular speakers, while welcoming free software developers, open source enthusiasts and virtually anyone who is interested.
One Desktop Per Ten A Workable ModelSubmitted by srlinuxx on Monday 22nd of September 2008 05:13:54 PM Filed under
ostatic.com: The Digital Divide -- there isn't a nation where it doesn't exist, yet it seems so relative. In one place, a child going online via dial up using a PII seems at a disadvantage. Elsewhere, that child has a tool that could change his life. Open source has much to offer here.
How Linux lost the battle for your desktopSubmitted by srlinuxx on Monday 22nd of September 2008 05:11:56 PM Filed under
techradar.com: A few years ago, it looked like Linux might – just might – take over the world. Companies like Lindows/Linspire were going to make it easy enough for your mother to use. Bright coloured boxes of SUSE and Red Hat and plenty of others were piled high in every computer store. It was going to be a whole new era. Except it didn't really happen, did it?
What's GNU, Part Four: findSubmitted by srlinuxx on Monday 22nd of September 2008 05:10:12 PM Filed under
linux-mag.com: A few months ago, we finished the third of a series about features added to longstanding utility programs. This month we'll look at the new features that GNU programmers and others have added to all of the other features that find(1) already had.
Consider these Linux file management alternativesSubmitted by srlinuxx on Monday 22nd of September 2008 05:08:19 PM Filed under
blogs.techrepublic.com: Many Linux users make use of the KDE or GNOME desktop environments and when it comes to file management, they don't venture beyond using the environment-provided file management tools like Konqueror or Nautilus. Considering this is Linux, there are many other file management tools to choose from, some of which you may find preferable to the "defaults."
Ubuntu Intrepid Ibex Alpha 6 - Good News for Laptop UsersSubmitted by srlinuxx on Monday 22nd of September 2008 02:17:45 PM Filed under
community.zdnet.co.uk/blog: I installed Ubuntu 8.10 (Intrepid Ibex) Alpha 6 on both of my laptops over the weekend, and it looks very good. In the original announcement of the Intrepid Ibex development, Ubuntu spoke of giving priority to "pervasive internet access", and it appears to me that they have made good progress on that.
Review: Linux Mint 5 - KDE EditionSubmitted by srlinuxx on Monday 22nd of September 2008 02:16:18 PM Filed under
raiden.net: Ever since I first ran into Linux Mint over a year ago, I've been enamored by it's elegant simplicity, rock solid stability, good hardware support, and excellent user experience. This distribution has continued to impress me time and again, and has really become my number one recommended distro, actually displacing PcLinuxOS in the top slot, for favorite new user friendly distributions.
A Linux Zealot Examines Microsoft VistaSubmitted by srlinuxx on Monday 22nd of September 2008 02:14:59 PM Filed under
blogs.techrepublic.com: I know, I know…you're wondering why this is in the open source blog. The reason is simple: I have used open source operating systems for a long, long time now. I have championed against Microsoft for over ten years. But when Techrepublic liked the idea of me writing some Vista content for them, I couldn't say no.
OpenOffice.org 3.0 Release Candidate 2 availableSubmitted by srlinuxx on Monday 22nd of September 2008 12:29:53 PM Filed under
The release candidate 2 of OpenOffice.org 3.0 is now ready for testing. This test release is made available to allow a broad user base to test and evaluate the next major version of OpenOffice.org, but is not recommended for production use at this stage.
8 hacks to make Firefox ridiculously fastSubmitted by srlinuxx on Monday 22nd of September 2008 12:29:09 PM Filed under
techradar.com: Firefox has been outperforming IE in every department for years, and version 3 is speedier than ever. But tweak the right settings and you could make it faster still.
Linux News: 10 years ago (Sep, 1998)…Submitted by srlinuxx on Monday 22nd of September 2008 12:27:54 PM Filed under
linuxscrew.com: Below are some Linux news which were on top 10 years ago at e-news sites of of that time.
DistroWatch Weekly, Issue 271Submitted by srlinuxx on Monday 22nd of September 2008 10:51:48 AM Filed under
This week in DistroWatch Weekly:
- Feature: Linux package management cheatsheet
- News: Testing OpenSolaris 2008.11, Fedora intrusion update, Ubuntu and kernel patches, netbook benchmark comparison, Gentoo decline
- Released last week: Pardus Linux 2008.1, PC-BSD 7.0
- Upcoming releases: Fedora 10 Beta, Mandriva Linux 2009 RC2
- New additions: Syllable Server
- New distributions: Dragora GNU/Linux, Orange Sombrero, Toorox
- Reader comments
Read more in this week's issue of DistroWatch Weekly....
Unadulterated OpenOffice.orgSubmitted by srlinuxx on Monday 22nd of September 2008 10:49:57 AM Filed under
blogs.pcworld.co.nz: A number of distributions mess around with OpenOffice.org and release their own versions. Personally, I prefer the unadulterated version. Not only do you get all the features, but you can also upgrade the moment the latest release is out and not have to wait for your distro's package maintainers to catch up.
Howto: Pimp your kickstart, Part oneSubmitted by srlinuxx on Monday 22nd of September 2008 09:53:10 AM Filed under
liquidat.wordpress: In Fedora and Red Hat/CentOS unattended installations are done via kickstart. It is also the tool of your choice if you want to set up several systems in the exact same way. With some simple tricks it can become even more useful.
Ubuntu Weekly Newsletter #109Submitted by srlinuxx on Monday 22nd of September 2008 09:50:00 AM Filed under
The Ubuntu Weekly Newsletter, Issue #109 for the week of September 14th - September 20th, 2008 is now available. In this Issue: Intrepid Ibex Alpha 6 released, Codecs & DVD playback in Intrepid for all users, and Mozilla Team Meeting Summary.
FastMailMerge rationalizes OpenOffice.org Merge functionsSubmitted by srlinuxx on Monday 22nd of September 2008 09:48:18 AM Filed under
linux.com: Mail merge, the production of multiple documents that differ only in minor details, remains a difficult task in OpenOffice.org Writer. Few use the function regularly, and when they do, the mail merge wizard seems to cause as much confusion as it resolves. FastMailMerge is not only simplicity itself, but a welcome relief that easily lives up to its name.
more odds & endsSubmitted by srlinuxx on Monday 22nd of September 2008 06:39:15 AM Filed under
- Linux I use
- Howto setup a Xen user domain using debootstrap
- How to get the process start date and time
- Novell's Javier Colado: Making His Move
- Attention Microsoft: I'm A PC (Running Ubuntu Linux)
- Famous Quotations Script
odds & ends & stuffSubmitted by srlinuxx on Sunday 21st of September 2008 11:50:17 PM
- Photoprint, Gutenprint's best friend
- VoIP From Home to Business Telecommunications with Debian
- Compiling C/C++ Code in Ubuntu and Available IDEs
- How To Find Files by Content Under UNIX
- VirtualBox Wireless Bridging with DHCP
- Ohloh and the popularity of programming languages
- How to change the start-here icon (Start Menu Icon) in Ubuntu
- How to install Subsonic Ubuntu Hardy
- MPlayer channel redirecting
- Using ffmpeg on Ubuntu to convert DV videos for video sharing websites
- Alien Arena 2008 v7.20 media release
- Linux 2.6.27-rc7
- Medion Akoya Mini (MSI Wind) 10-week Review
Why I love DebianSubmitted by srlinuxx on Sunday 21st of September 2008 07:48:00 PM Filed under
euneeblic.livejournal: Ubuntu and Linux Mint are great for new users, but I'm not a new user. I'm not trying to be snobby, and I don't think I'm better than anyone else; I just have different needs than most people. I don't want polish. I want to see and work with the guts of my operating system.
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Avidemux 2.6.13 Open-Source Video Editor Gets AAC/ADTS Import and Export
The developers of the Avidemux open-source and cross-platform video editor software have announced a new maintenance update in the 2.6 series, bringing multiple improvements, bug fixes, and a handful of new features.
5 Best Linux Distros for Security
Security is nothing new to Linux distributions. Linux distros have always emphasized security and related matters like firewalls, penetration testing, anonymity, and privacy. So it is hardly surprising that security conscious distributions are common place. For instance, Distrowatch lists sixteen distros that specialize in firewalls, and four for privacy. Most of these specialty security distributions, however, share the same drawback: they are tools for experts, not average users. Only recently have security distributions tried to make security features generally accessible for desktop users.
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Kate Plays Christine
An actress prepares to play the role of a suicidal news anchor, and is slowly transformed by the experience.
An actress prepares to play the role of a suicidal news anchor, and is slowly transformed by the experience.
War Dogs is a film about horrible people that refuses to own their horribleness.
Roger Ebert on James Ivory's "Howards End".
"The Ballad of Narayama" is a Japanese film of great beauty and elegant artifice, telling a story of startling cruelty. What a space it opens…
Ken Loach's "I, Daniel Blake" wins the Palme d'Or at the 69th Cannes Film Festival.
Barbara Scharres on the cats of Cannes 2016.
Chaz Ebert writes about the Q&A she moderated with the filmmakers of "Southside with You," and her experience of meeting President Obama for the first…
The Alliance of Women Film Journalists presents its list of top female fiction characters.
The third part in a series on the way Islam is represented in Western cinema.
An FFC (Far Flung Correspondent) reviews "Son of Clowns."
An interview with actors Tika Sumpter & Parker Sawyers about portraying Michelle & Barack Obama on their famous first date in "Southside with You."
An interview with executive producer John Legend about "Southside with You," composing the end credits song "Start" for the film's closing credits and much more.
Since he started as film critic for the Chicago Sun-Times in 1967, and began covering movies locally and at international film festivals, Roger Ebert has met and interviewed countless movie idols, artists and unknowns -- some of them even before they became famous. There's hardly a major figure in the history of movies, from the last part of the 20th century into the 21st, that he hasn't encountered.
Chadwick Boseman steps into the legendary shoes of the hardest-working man in show business this weekend with the release of Tate Taylor's "Get On Up," the biopic of James Brown. The star of "42" sat down recently with his director to discuss the difficulty of playing one of the most beloved figures in the history of music.
Next Article: Calm in the Storm: John Michael McDonagh, Brendan Gleeson on "Calvary" Previous Article: Simply Do it: Talking with Woody Allen About Directorial Style
A look back at how this summer's best offering, Netflix's "Stranger Things," makes the failure of this season's block...
This message came to me from a reader named Peter Svensland. He and a fr...
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Swarovski Elements Stardust Ring£9 instead of £59 (from Rocks of London) for a Swarovski Elements stardust ring - sparkle and save 85%
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- Get a stunning stardust ring.
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- May buy multiples.
- Voucher valid until 7th Mar 2014.
- Postage costs an additional £3.99 per item.
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Full Details
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List all words starting with tannable
Only the word tannable was found, nothing longer.
Some random words: do via lo chablis eobiont ebon wud
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Lots of kids of all ages and genders love playing with My Little Pony, and now they can cuddle up with the My Little Pony Twilight Sparkle 20-inch Plush. Just like the smaller version, Twilight Sparkle has her individual cutie mark embroidered on her. This large toy is very well made, and polyurethane foam inside will stand up to lots and lots of hugging and keep its shape.
This large, stuffed version of Twilight Sparkle is soft, cuddly, and completely charming. Little kids will love it as a huggable pet with braidable ribbon hair, and for older fans, this will be whimsical room décor. It's a brand new way to play with and love these classic characters.
My Little Pony Twilight Sparkle 20-inch Plush is for My Little Pony fans ages 3 and up.
In addition to Twilight Sparkle, Funrise makes 20-inch versions of Pinkie Pie and Fluttershy. Each is sold separately.
The toy is surface washable only.
Go! Go! Smart Friends Secret Blossom Cottage
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Disney Princess Magical Wand Cinderella
from Jakks Pacific
Strawberry Shortcake Blueberry Muffin Classic Doll
from The Bridge Direct
Popples Lulu Pop Up Figure
from Spin Master
Popples Izzy Pop Up Figure
from Spin Master


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Browse through trees of the world, categorized by country. When you click a tree link, photos are retrieved from Flickr and displayed.
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Pine Rest Christian Mental Health Services is hiring Registered Nurses for our Inpatient Hospital on our main campus in Grand Rapids!...
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1 year LTC Charge Nurse:. The Charge Nurses' primary responsibilities include, but are not limited to;...
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CENTRIA HEALTHCARE: REGISTERED NURSES (RN) AND LICENSED PRACTICAL NURSES (LPN) FOR PRIVATE DUTY NURSINGCentria Healthcare has developed a comprehensive program to care for individuals involved in the most serious accidents with potentially long term complications related to those accidents.• Visit/Shift work• Competitive pay• Vent and Trach training provided• Part-time or Full-time work ...
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Looking for the largest selection of Cardiac Cath Lab travel jobs? Look no further. If you're a Cardiac Cath Lab RN that is ready to start a travel nursing
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Established operations in pleasant independent senior living communities need strong LPN's to supervise and oversee their medication administration programs, provide clinical education and leadership, and continue to assist in developing a growing client base. Both part time and full tome positions are available. These positions require LPN's with med surg experience, at least 3 years as a ...
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Progressive Care Unit RNsÉ starting a travel career has never been so easy. At Cross Country TravCorps, our list of travel positions is growing everyday. From
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Per Diem, experienced, Registered Nurse (RN) needed for busy Ophthalmology practice in Muskegon. This position is at the Ambulatory Surgery Center.Provides care to patients in the pre-op and post-op areas with care and compassion.Documents thoroughly and efficiently in the EMRRequires excellent assessment and critical thinking skillsProvides patient/family educationMaintains a positive ...
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ASK AND WE ANSWER your questions on Marketing and website optimization.
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1 pound away from my goal weight, now I'm gonna start muscle building.
I was 135 pounds at my biggest (BMI was 25.5, overweight. I'm hella short). I'm proud of losing the weight (didn't even exercise, just stopped consuming shitty food and started drinking only water)
But I have NO muscle whatsoever and that needs to change. I don't know why my belly sticks out like that but I've always hated it. Gonna focus on core workouts and maybe it'll shrink. My carb intake is also way out of control which I think is causing weird swelling in my abdomen.
As of now: 101 lbs, 31″ around at my belly.
I wanna get swole and throw dudes over my head but first I need to be able to do one single pushup lmao


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Associate Scientist
Momentum Scientific - Chicago, IL
A quickly growing pharmaceutical company is looking for an Associate Scientist to join their expanding team. Candidates will be cross-trained in multiple
Research Administrator
Northwestern University - Chicago, IL
The Research Administrator provides administrative leadership and intermediate problem solving in support of unit's research programs and mission. This
Chemist II
Medix - Skokie, IL
KNOWLEDGE, SKILLS AND ABILITIES Knowledge of laboratory and chemical principles, terminology material, equipment, procedures, and techniques. Knowledge of
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Metabyte, Inc. - Abbott Park, IL
Job Title: Associate Scientist I Location: Abbott Park, IL Client: Abbott Laboratories Duration: - 1+ year contract Job Description: Assist in developing/
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Metabyte, Inc. - Abbott Park, IL
Position : Chemist IIILocation: Abbott Park, IL Client: - *Abbott Laboratories* *Job description: * BS in Chemistry 7+ years experience, MS in Chemistry 2+
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*Description: * A postdoctoral researcher is needed for a neuroscience lab at Northwestern University Feinberg School of Medicine. Our research is focused on
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A Research Specialist is sought in the area of Mass Spectrometry to prepare samples, acquire data on state-of-the-art mass spectrometers, and analyze the data
Cook County Health & Hospitals System - Chicago, IL
Under minimum supervision, exercises a high degree of independent judgment and technical expertise as a Medical Technologist by performing tasks of high
Research Technologist 2
Northwestern University - Evanston, IL
The Quantitative Bio-element Imaging Center (QBIC, qbic.northwestern.edu) at Northwestern University is seeking exceptional candidates for a research


text:
Of all the government agencies, NASA is among the hardest hit by the government shutdown. As of Oct. 1, nearly all of its employees have been told to pack up and head home.
But there are two NASA workers who can't leave the office, at least not without great expense to the taxpayer. Astronauts Karen Nyberg and Mike Hopkins are orbiting some 250 miles above Earth aboard the International Space Station. They're in touch with mission control, but it's not clear they have all that much to do.
Intriguingly, while nearly all of NASA's Twitter feeds are offline, Nyberg and Hopkins have both tweeted since the shutdown began. And their tweets hint that they might be just a weensy bit bored:
Have you ever watched the clouds go by & let your imagination see different shapes? It works from space as well. pic.twitter.com/LpEJHmGGpv
Say cheese! pic.twitter.com/ShjsvD0QCj
1st pic of day. I messed up & hit button while grabbing the camera, but I thought it turned out to be a neat shot pic.twitter.com/tePOEt2Zne
Neither astronaut immediately responded to an NPR reporter's tweet, asking them whether they were among the furloughed NASA employees.
Read original article – Published October 03, 2013 6:08 PM
Shutdown Quiets NASA, So Space Station Astronauts Enjoy View
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Red Carpet Concert: Chantil DukartIn collaboration with Trickster Company and Kindred Post we present the 2016 Celebration Sessions featuring jazz artist Chantil Dukart
Forest service gives go ahead for Kuiu Island timber saleAn old growth timber sale recently announced in a Ketchikan newspaper has one conservation group scratching its head. That's because this type of harvest, near valuable salmon streams, won't be allowed in the future.
Elections office still waiting on ballots to arrive by mail in tight House primaryBallots are still outstanding from four precincts in District 40: Selawik, Browerville, Anaktuvuk Pass and Ambler.
Enhanced IDs help some tribal members cross bordersEnrolled members of Alaska's largest tribal government are getting enhanced photo IDs. They can be used for border crossings and some other situations where official identification is necessary.


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spaceman_spiff (Tyler Palmer)
Last login: Saturday, April 2, 2016
Comment history
City Commission to decide who will be mayor for the rest of 2016
We need fewer partisan elections in this country, not more.
Having candidates lining up behind and beholding to political parties and ideologies causes more problems than it solves. The two main political parties in the US have their own agendas which, more often than not these days, do not have much in common with what is best for the citizenry or country and only serve the parties themselves and their donors.
Would be much nicer if candidates had to run on their own merits and backgrounds rather than getting elected just because of their party affiliation. Low-information voters also might have to learn a bit about the candidates instead of voting based on the letter next to their names. I'm more than sick of elected officials that refuse to represent everyone in their district and instead only represent their narrow, partisan, ideology. They weren't elected to just represent their special interest group, they were ostensibly elected to represent everyone in their district.
April 2, 2016 at 12:58 p.m. ( permalink | suggest removal )
Poll: Brownback and Legislature less popular than Obama; Kansas Supreme Court rated highest
Here's the 2014 election results by county:
And here are the turnout numbers by county.
The election was close and Brownback only won by roughly 32,000 votes. Wyandotte county had poor turnout. Better turnout there would have dramatically aided Davis. The two counties with the largest populations both went for Brownback: Johnson county by over 2000 votes and Sedwick by about 3000. That election was a good example of why it's so important for people to participate and vote.
March 4, 2016 at 7:08 p.m. ( permalink | suggest removal )
Would you ride the bus if it were free?
It's not the cost, it's the convenience. I can spend an hour each way on the bus to get from home to work or I can spend 15 minutes in my car.
March 1, 2016 at 8:59 a.m. ( permalink | suggest removal )
Lawrence City Commission to vote on traffic control, other items for 800 New Hampshire apartment project
They're building a $7 million structure and are worried about needing to pay another $70k to acquire land they want to develop as part of that project? Sheesh. Most people have to pay for things they want that someone else owns.
March 1, 2016 at 8:57 a.m. ( permalink | suggest removal )
Effort by Kansas lawmakers to repeal Common Core standards could end AP, IB programs
Wow. Multiple examples from this week of our state legislature refusing to hear from anyone other than the shills for the horrible policies they want to enact. Completely irresponsible.
February 20, 2016 at 6:06 p.m. ( permalink | suggest removal )
Kansas Senate panel puts brakes on KU Central District project
With all the restrictions, strings, and interference that comes with accepting state funds, it often seems like KU would be better off not being a state school. Our legislature has shown over and over it likes to meddle in education matters at all levels without the necessary knowledge, skill, or thoughtfulness to do so responsibly.
February 8, 2016 at 4:42 p.m. ( permalink | suggest removal )
Kansas among several states looking to ban sanctuary cities
But those issues are so hard. They require effort, compromise, and ignoring the Governor's unrealistic belief in failed economic ideology and threats to veto attempts to return to a more reality-based system of governance.
February 2, 2016 at 5:04 p.m. ( permalink | suggest removal )
State attorney general: Kansas needs to vote on Supreme Court selection process
I do not want judges elected based on partisan affiliation and ideological purity. I want judges to make decisions based on a sound legal basis that is not beholding to party politics and under the threat of a lack of support in the next election if they don't decide cases "the right way".
Do we really want to follow in the footsteps of Alabama and the disgusting behavior of Judge Moore who believes his personal religious and political beliefs trump what the US Supreme Court has decided is settled law?
February 2, 2016 at 4:50 p.m. ( permalink | suggest removal )
Lawmakers moving quickly to balance budget
The current plan from the Governor and others is the same, ignorant, kick-the-can-down-the-road plan they have done every year since enacting the flawed tax cut legislation. Using one-time sweeps and other accounting gimmicks does nothing but drain funds from programs robbed of their previously allocated dollars and force each successive legislature to have to make more and more politically-difficult decisions. Legislators ought to stop letting Brownback dictate what ideas they will and will not consider in order to actually resolve the states ongoing revenue problems.
January 31, 2016 at 12:08 p.m. ( permalink | suggest removal )
Minority groups push for same-day voter registration
If the standard for the voter to qualify and his/her vote to count is exactly the same as registering any other time throughout the year, it is illogical for Kobach and others to suggest that same-day registration would result in more fraud than the current registration process. It's effectively the same process for qualifying, just without pre-election deadline.
The only conclusion that can be drawn from opposition to this legislation is that it has nothing to do with preventing fraud and instead suggests that those opposed are trying to suppress voting.
January 31, 2016 at 12:01 p.m. ( permalink | suggest removal )
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"Strong signals", potentially linked to alien life, have been picked up by a radio telescope operating in a remote corner of Russia.
Sara Connor and David Taylor to reenact the night Bali police officer died
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Palmer Holland, Inc.
100 - 249
20 - 50 Million
Services->Other Biz Services
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2899 - Chemical Preparations, Nec
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Home › Forums › Gear Forums › Make Your Own Gear › fake down booties?
I've got a ton of apex left over from making the quilts, and I was going to make some down bootie knockoffs with some of the excess. Are there any patterns out there? What would you use as the sole?
@b-g-2-2Locale: Silicon Valley
I did a Polarguard bootie kit once many years ago. The inner sole was closed cell foam covered by nylon. The outer sole was a tough Cordura nylon with some texture.
@retiredjerryLocale: Oregon and Washington
I made some synthetic "booties" just for sleeping.
Just a tube with the end sewn off at an angle:
On my foot:
To sew it, do a French seam – do a loop of fabric, loop of insulation, loop of fabric – fold over and sew through them, cut off all but about 1/4 inch, turn inside out and sew through it hiding the raw edges, turn it right side out – do the same thing to close off the foot
Thanks Bob and Jerry!
I couldn't figure out what to do inside the sole, but closed cell foam makes perfect sense. Now I suppose I need to decide if they will just be worn in the tent or not because Jerry's idea sounds really good as well. At the very least, I think I will make a pair of Jerry's design for my son to keep his feet warm at night.
@intothemysticLocale: PNW
I've got a pair of Feathered Friends down booties that I'd be happy to 'loan' you so you can get ideas on how to make your own since you're in the area. I wouldn't need them back for a couple of weeks. PM me if you're interested.
@b-g-2-2Locale: Silicon Valley
Booties are made to different degrees of seriousness. Down socks would be worn only inside a tent. Down booties could be worn inside, or maybe outside. Some have seriously textured soles so that you can go outside into the snow on a midnight visit.
My Polarguard booties are OK, but they are a little heavy. That was my first kit to assemble.
I made mine with Polarguard 3D, used two layers of 3oz if I recall correctly. Differentially cut. 1.1 oz ripstop outer, lining was pieces of a really light blanket I got on an airline – basically a brushed fabric that is really light, like maybe 2 oz/yd. I did the brushed lining so I could put them on with no socks and be comfortable, which I sometimes do. I like the lining. Soles are 160d cordura with 1/4" closed cell foam. For outdoors I have overbooties, knee-high single layer fabric (1.1 rip top again) with 3/8" foam in the soles. So when I go out I have a total of 5/8" foam underfoot.
I also tried Toughtek (a kind of grippy rubberish frabic that I have used for mitten shell palms) for the soles, but it was slippery on ice – not good.
I had made pile booties before, and had a pattern that I developed for those. I modified that pattern and made two versions of it, one larger for the outer layer, one smaller for the inner. Making a pattern for booties is pretty easy by trial and error if you have some scrap fabric to play with.
@rcaffinLocale: Wollemi & Kosciusko NPs, Europe
Jerry's design is straight. Looks funny, but check how you sleep. Most people sleep with their toes pointed out straight. So the design works better than expected.
@lettheguydanceLocale: Midwest
why fake?
anyways, here's a pair I made using synthetic insulation, CCF "midsole" and a "slip-not" (i think from quest outfitters, or maybe rockywoods) outsole:
@francoLocale: Tarptent
if you make your own they will be 100% genuine originals…
(booties is not a brand name or a specific product)
not too good,and I think it is fake booties
By fake, I meant not actually down, since I'm going to use Apex.
I think I'm going to start with the tube sock design. I love the idea of having an over-sock so that way I won't get the quilt dirty.
Thanks for everyone's ideas!
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India v Australia, 3rd Test, Mohali, 3rd day
Dravid: What Dhawan did is hard to believe-1
Interviewer: Gokul Chakravarthy
- Players/Officials : Shikhar Dhawan
Interviewer: Gokul Chakravarthy
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two great debutants seen in d last 2 weeks Hamish Rutherford n Shikhar Dhawan
Dhawan has made a fantastic debut, and based on what I read in an article in TOI wherein the selectors want Sehwag to improve his attitude and for the time being have decided to restrict Gambhir to ODI's, I think they have finally gotten it right.
Prior to Dhawan's innings, Laxman thought that Sehwag was just about to hit form and it was wrong to drop him. After Dhawan's innings Dravid in his interview was quick to clarify that celebrate Dhawan's innings today but just based on one innings he is not a great like Sehwag yet. Now both of these people are obviously attached to their former team mate and might have made valid points. It may also be argued that Sehwag and Gambhir still have talent and a few years left in them.
Plus who knows, Dhawan might fail in his first trip to South Africa and England and it is premature to make him a God based on one innings. But I will still insist on making Dhawan the first choice opener for South Africa and England with Sehwag as the reserve
Rahul needs to get closer to the microphone and maybe speak a little loudly so that we can get a better quality recording.
What is the point of having a video when you cant even hear Dravid's voice properly. The quality is pathetic!
@ salman abubacker....but they are still no. 3...so they can be one of the greats
Agree, and we need to see also that Australian and world cricket doesn't find a strong weakness (like short ball for Kambli) in his batting....... Though lets enjoy another record in name of an Indian.......... :)
@salman, i do think so....
@Bipin I don't think nowadays Australia is the greatest team... they are the weakest Australian team ever
records upon records are being made and its against one of the greatest team ever.. so its a good kind of cricket that India is playing so far.
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Mayors set example by delivering hot meals to seniors
|Fairlawn residents Cecil and Betty Miller received a hot meal March 20, delivered by Fairlawn Mayor William Roth as part of Mobile Meals' Mayors for Meals week.
|Akron Mayor Don Plusquellic delivered a meal to the home of 91-year-old Kenmore resident Louise Hooper March 20 during Mayors for Meals week.
|Photos courtesy of Mobile Meals Inc.
During Mayors for Meals Week, held March 18-22, more local mayors than ever volunteered to show their support for homebound and hungry seniors in the area by making deliveries to their constituents, she said.
The goal is to bring awareness to senior hunger, she said.
"Ohio ranks 15th in the country for seniors that are at risk for hunger," she added. "Personally, I don't think that's acceptable."
A pleasant side effect of Mayors for Meals Week, though, is that it offered the opportunity for some seniors to bend the ears of their mayors, she said.
In Akron, Mayor Don Plusquellic delivered a meal to 91-year-old Kenmore resident Louise Hooper March 20. On the same day, Fairlawn Mayor William Roth took a meal to Cecil and Betty Miller.
Roth said he enjoyed his visit with the Millers, who are longtime residents of Fairlawn and remain active in the community.
Though Roth said he had known of Mobile Meals for years through guardianship work, he was impressed with the organization's "smooth" operations. The meals he delivered were hot and ready to go, and the food looked good, he said.
The organization is "definitely something that deserves our support and an asset in our community," he added.
The week also included meal deliveries by Cuyahoga Falls Mayor Don Robart and Norton Mayor Mike Zita. Other Northeast Ohio mayors' participating cities included Barberton, Bedford, Green, Kent, Medina, Ravenna, Stow and Twinsburg.
According to organization officials, normally one of Mobile Meals' 69 staff members or around 200 volunteers make sure more than 2,500 meals and supplements are delivered to the homes of children, the disabled and the elderly each day, to residents in Summit County, as well as Medina, Portage, Cuyahoga and Lorain counties.
Mobile Meals has served Northeast Ohio for 42 years, providing meals and nutrition services to individuals of all ages who are at nutritional risk. However, the agency could use closer to 1,000 volunteers, said Travaglino. That need amounts to 792 volunteer hours of driving a month, she said.
Every year, Mobile Meals experiences budget cuts that come through the federal budget, according to Travaglino. She said since the beginning of March, when Congress made the decision to sequester, Mobile Meals stands to lose about $12,000 that were direct dollars to seniors.
Though the most recent cuts have not impacted Mobile Meals' services, the organization did have to make some changes last year, said Travaglino.
"We continue to be efficient with our dollars — we are more efficient that we've ever been," she added.
A hot meal almost doubles in cost because of the delivery cost associated with it, she noted.
"This agency needs people to say, 'If my mayor can deliver a meal, I can deliver a meal to someone,'" she said.
Those interested in volunteering to deliver meals need to provide their own gas and vehicles. Mobile Meals will do their best to accommodate volunteers' schedules and set them up to deliver meals in their area, she said. Some training and security checks are needed before volunteers can get going, she added.
"It just really provides a meaningful volunteer experience," she said. "So often when someone goes to volunteer, they don't get a people connection," but delivering meals for Mobile Meals offers the opportunity to touch someone's life directly, she said.
Also, in the past volunteers were only needed Mondays through Fridays, but now some Saturday volunteer hours have opened up, so families can go together, said Travaglino.
For more on volunteer opportunities, contact Laura Purdy at 330-376-7717. For more on the organization, also visit www.mobilemealsinc.org.
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McLaren disputes Red Bull appointment
McLaren-Mercedes McLaren has disputed Red Bull's appointment of Dan Fallows of head of aerodynamics with the reigning world champions. Red Bull confirmed on Wednesday that Fallows would replace Peter Prodromou, who was revealed last year to be re-joining McLaren. Prodromou has been placed on gardening leave ahead of a scheduled move to McLaren. Fallows left Red Bull in 2013 for a brief period but McLaren is adamant that they have a contract with Fallows. 'Dan Fallows has a legally binding contract with McLaren and the matter is now in the hands of our lawyers,' said McLaren.
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Written on: 16/08/2012 by jackboy18 (1 review written)
very happy with my dealing with ashcycles.got a good price and my bike was here next day.will use again.
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DISCLAIMER: Barco NV is not responsible and cannot be held liable in any way for the accuracy, completeness or validity of the information, figures, calculations or assumptions that have led to this overview. The figures indicated as 'consensus' do not in any way represent Barco's financial expectations nor can this be considered to be a forward looking statement by Barco.
3059 Premiere Parkway Suite 400Duluth, GA 30097United States
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Barco & High End Systems fuel excitement in Drake's 'Summer Sixteen' tour
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The red-haired mistress Tura slaps the face of her slave. She wants to humiliate him and show him who is the boss. She orders him to press his head to the floor; that's his place. Of course his slave face gets slapped again and again. Keep your head straight – so that she can take better aim!
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Hacked By: selectLOL
Hack Information:
Hackbar: Press 1 Attempts - 2 Win level
Game Information
Get the Toy is an awesome physics-based puzzle game, it makes you remember your childhood of hunting for toys. You must catch at least one toy in each level, you have only three attempts.
Cheats: Hackbar: Press [5] Money - [6] Upgrade points
Hacked By: selectLOL
Cheats: Hackbar: Press [1] Fairy - [2] Key - [3] Bomb - [4] Fire mod...
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Cheats: Hackbar: Press [1] Freeze enemy (Press again to unfreeze) - ...
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Hacked By: leverage419
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Samsung to launch Ativ Book 9 Plus laptop Aug 18
August 9, 2013 - 21:31 AMT
PanARMENIAN.Net - Samsung is kicking off its Ativ Book 9 Plus laptop at a price tag of $1,399, CNET reports.
Popping up for pre-order in the U.S. on August 18, the Ativ Book 9 Plus offers a 13.3-inch screen with a hefty resolution of 3,200x1,800 pixels, prompting CNET to dub it "possibly the highest-resolution 13-inch laptop around."
Outfitted with Gorilla Glass, the display is 2.8 times sharper than a full HD screen, according to Samsung. The screen's SuperBright technology is rated at 350 nits, which means it's designed to hold its brightness even under sunny outdoor conditions.
The display panel can tilt back to 180 degrees and lock in at 110 degrees to provide a more solid touch-screen feel. Equipped with Windows 8, the Plus offers a ten-point multi-touch screen, CNET says.
At the $1,399.99 price, the Plus is powered by a fourth-generation Intel Core i5 processor and comes with a 128GB solid-state drive and 4GB of RAM. The battery is designed to last 7.5 hours on single charge.
Samsung also has a new Windows 8 tablet up its sleeve.
Selling for $699.99, the Ativ Tab 3 will be available to consumers starting September 1.
The new tablet offers a 10.1-inch five-point touch screen with a resolution of 1,366x768. An Intel Atom processor provides the power and a 64GB SSD provides the storage. A 720p camera adorns the front, while a 2-megapixel model is in the rear. And the battery offers 7 hours of life on a single charge.
Tab 3 buyers also get an S Pen stylus and a Bluetooth keyboard that can serve as a cover and kickstand. Samsung clams the Tab 3 is the world's thinnest Windows 8 tablet at 0.31 inches thick and a weight of 1.28 pounds. The tablet comes with Microsoft Office Home and Student edition along with Samsung software designed to take advantage of the S Pen.
Finally, both the Book 9 Plus and Tab 3 can tap into Samsung's SideSync feature.
Geared toward owners of Samsung smartphones, SideSync lets you connect the phone with the Samsung laptop or tablet via USB cable or Wi-Fi. Uners can then run certain tasks across the different devices, such as texting on the phone from the PC's keyboard, viewing photos stored on the phone through the PC monitor, and moving files from one device to the other, CNET says.
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