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Superiority of the DNA Amplification Assay for the Diagnosis of C. difficile Infection: A Clinical Comparison of Fecal Tests
- First Online:
- Received:
- Accepted:
DOI: 10.1007/s10620-012-2200-x
- Cite this article as:
- Barkin, J.A., Nandi, N., Miller, N. et al. Dig Dis Sci (2012) 57: 2592. doi:10.1007/s10620-012-2200-x
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Clostridium difficile infection (CDI) is a major infectious concern, accounting for substantial morbidity and resource utilization. Advances in microbiological and molecular techniques have resulted in an increasing number of testing options for CDI. A glutamate dehydrogenase (GDH) enzyme immunoassay (EIA) and a DNA amplification (DNA-A) test for the diagnosis of CDI have recently become commercially available.
The aim of this prospective study was to compare the test performance characteristics of the traditional diagnostic modality for CDI diagnosis, the toxin A/B (TOX) EIA, with those of the GDH EIA and DNA-A test, utilizing enriched toxigenic culture (TGC) as the gold standard. Clinical variables predictive of CDI were also studied.
Participants fulfilled one or more criteria placing them at increased risk for CDI. Each stool sample was tested by each of the methods mentioned above. Clinical data parameters were collected via a 12-month review of the electronic medical record prior to the index date of the first stool test.
A total of 272 stool samples from 144 admissions of 139 patients were evaluated for CDI. The sensitivity and positive predictive value (PPV) of the TOX EIA were 86.1 and 58.4 %, respectively, whereas the sensitivity and PPV of the GDH EIA and DNA-A test were 100 %. 1.8 % of the GDH tests yielded inconclusive results. Using TGC as the gold standard, nosocomial exposure with emphasis on nursing home residence, history of previous CDI, and female gender were predictive of CDI.
Test performance characteristics of the DNA-A test and GDH EIA were superior to those of the traditional TOX EIA. The GDH test is limited by inconclusive test results and requires a multi-step diagnostic algorithm. Therefore, the DNA-A test should be implemented as the diagnostic method of choice for CDI. CDI clinical predictors are important for diagnostic decision-making.
KeywordsClostridium difficileDiagnosisImmunoenzyme assaysDNA amplification
Clostridium difficile infection (CDI) is a major infectious concern, accounting for substantial morbidity and resource utilization. From 2000 to 2005, there was a 23 % increase in nosocomial Clostridium difficile-associated diarrhea (CDAD) in the USA, with an increase in CDAD-related fatality rates from 1.2 to 2.2 % [1]. On average, patient length of stay was extended by 3.6 days and required an additional $3,669 expenditure per patient as compared to those without CDAD [2]. Data from the Healthcare Cost and Utilization Project in 2008 estimated that CDAD accounted for 348,950 hospitalizations annually, and a 2009 estimate placed the approximate costs of CDAD at $3.4 billion annually, more than a tripling of the estimates from only 7 years earlier [3–5].
Advances in microbiological and molecular techniques have resulted in an increasing quantity of testing options for CDI. The advent of toxin (TOX) enzyme immunoassay (EIA) testing in the 1990s enhanced the diagnostic capability for CDI by enabling direct assessment of the presence of C. difficile toxins A and B. Though clinically useful, this test is prone to inaccuracies due to specimen collection and toxin degradation prior to processing. A glutamate dehydrogenase (GDH) EIA and a DNA amplification (DNA-A) method for the diagnosis of CDI have recently become commercially available, with the DNA-based test theoretically offering the advantage of more consistent diagnoses independent of specimen and environmental factors that affect the reliability of the toxin A/B EIA test. While not routinely used due to lengthy time for results reporting, toxigenic culture still remains the gold standard for CDI diagnosis [6].
In the current health care environment that emphasizes cost control measures and appropriate utilization of resources, identifying clinical predictors of disease can result in better clinical decisions and more efficient care. Using the TOX EIA to determine the presence of CDI, prior studies have identified a myriad of associated clinical predictors of CDI, including antibiotic use, proton pump inhibitor (PPI) use, and healthcare-associated exposures [3, 6, 7]. Although generally accepted as associated with CDI, these potential predictors have not been formally evaluated when CDI was determined with newer diagnostic modalities.
The aim of this prospective study was to compare the test performance characteristics of the traditional toxin A/B (TOX) EIA, glutamate dehydrogenase EIA, and DNA amplification (DNA-A) assay for diagnosis of CDI, utilizing toxigenic culture (TGC) as the gold standard. Clinical variables predictive of CDI were also identified.
Study Population
Subjects were derived from inpatients at Mount Sinai Medical Center (Miami Beach, FL), a large community teaching hospital, during the study period from September 1, 2010 to March 1, 2011. Daily orders placed and receipt of specimens by the laboratory for C. difficile toxin A/B (TOX) EIA were the basis by which physicians obtained consent for patient enrollment in the study. The electronic health record was reviewed to identify clinical factors meeting inclusion criteria. Patients eligible for inclusion in the study were 18 years of age or older, had diarrhea (defined as three or more bowel movements in 24 h), had stool samples submitted for CDI testing per clinician discretion, and were able to provide consent for study enrollment. Participants also fulfilled one or more of the following criteria placing them at increased risk for CDI: prior history of CDI, nosocomial exposure in the previous 6 months, antibiotic PPI use within the previous 3 months, age ≥65 year, or the presence of nasogastric or post-pyloric feeding tube. Subjects were excluded if they were currently being treated for documented CDI and then re-tested for CDI during the study period, or if stool samples were not tested by all four laboratory testing modalities under consideration herein. Institutional Review Board approval was obtained.
A total of 139 patients (80 men, 59 women, median age 70.5 years) were included in the study population. The median age of patients with CDI was 78 years, whereas that of patients included in the study without CDI was 69 years [p = 0.082, not significant (NS)].
Laboratory Analysis
Specimens were refrigerated upon arrival to the laboratory, and C. difficile TOX EIA testing was performed daily. In accordance with laboratory policy, specimens received more than 2 h after collection were rejected for testing, and only specimens of unformed stools were accepted for testing. Laboratory policy allows submission of a maximum of three stool specimens collected on different days for testing from any one patient admission. Samples from each patient were included in the study until there was one C. difficile TOX EIA positive result, or a maximum of three negative C. difficile TOX EIA results. Each stool sample underwent four tests: (1) TOX EIA (Meridian Premier Toxins A and B Microwell EIA; Meridian Bioscience, Cincinnati, OH); (2) illumigene C. difficile DNA Amplification Assay (Meridian Bioscience); (3) GDH EIA testing (ImmunoCard C. difficile; Meridian Bioscience); (4) enriched TGC. Positive results in the TOX EIA were indicated by measuring optical densities at 450 and 630 nm (OD450/630) of ≥0.100. The illumigene C. difficile assay utilizes loop-mediated isothermal DNA amplification (LAMP) to detect the pathogenicity locus (PaLoc) of toxigenic C. difficile. The PaLoc is a gene segment present in all known toxigenic C. difficile strains; it codes for both the Toxin A and Toxin B genes, has conserved border regions, and is found at the same site on the C. difficile genome in all toxigenic strains [8]. The assay detects the PaLoc by targeting a partial DNA fragment on the Toxin A gene selected as an intact conserved region remaining in all known A+B+ and A−B− toxinotypes. Each reaction device contains an internal control to monitor for amplification inhibition. The ImmunoCard C. difficile EIA detects the presence of GDH, which is a common antigen found in both toxigenic and non-toxigenic isolates of C. difficile. Positive results are detected visually by presence of a color change in the test reaction port. Specimens that lack detectable color change in the control reaction port are interpreted as invalid. Enriched TGC served as the gold standard for the diagnosis of CDI to which all other modalities were compared. Specimens were subjected to alcohol shock with 95 % alcohol followed by culture in chopped meat anaerobic broth for 24–48 h. The broths were filtered and tested for toxin production by the Premier Toxins A and B Microwell EIA after 24 h of incubation; if negative, they were tested again after 48 h of incubation. True positive and negative values were defined by the reference TGC results to calculate sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy. An external technical review team from Meridian Biosciences examined the laboratory procedures at the mid-point of the study to ensure technical fidelity for assays.
Clinical Analysis
Clinical predictors collected for analysis
Patient demographics
Physical examination
Fever, defined as temperature >38.0 °C
Hemodynamic Instability (blood pressure <90/60 or heart rate >100)
Abdominal distension
Abdominal tenderness, rebound, or guarding
Laboratory markers
WBC >11,500 cells/mm3
Left shift of neutrophils (bands >20 %)
Increase in creatinine >50 % of baseline
Elevated lactate
Radiologic markers
Abdominal X-ray or computed tomography performed
Colonic distension
Colonic wall thickening
Peri-colonic fat stranding
Colonoscopic markers
Presence of pseudomembranes
History of CDI
Nosocomial exposure (hospital, nursing home, or both)
Antibiotic use and antibiotic class
PPI use, type and frequency
ICU admission (current or previous)
IBD (Crohn's disease, UC, or indeterminate colitis)
Human immunodeficiency virus
Diabetes mellitus
Immune-compromised state
Systemic steroid use
Chronic kidney disease
Nasogastric/gastrostomy/jejunostomy tube
Statistical Analysis
Univariate logistic regression analysis using the chi-square test was performed to establish clinical variables significantly associated with CDI, and continuous variables were evaluated using the Student t test. PASW (SPSS) ver. 18 software was used for statistical analysis.
Laboratory Testing for CDI
Comparison of diagnostic tests for CDI using toxigenic culture as the gold standard
Toxin A/B (TOX) EIA
86.1 % (31/36)
100 % (35/35)
100 % (36/36)
90.7 % (214/236)
100 % (232/232)
100 % (235/235)
58.4 % (31/53)
100 % (35/35)
100 % (36/36)
97.7 % (214/219)
100 % (232/232)
100 % (235/235)
Inconclusive tests
1.8 % (5/272)
0.4 % (1/272)
86.3 % (235/272)
100 % (267/267)
100 % (271/271)
Clinical Predictors of CDI
Clinical predictors significantly associated with CDI
Clinical predictor
Negative CDI
Positive CDI
p value
Nosocomial exposure
25 (22.5 %)
3 (10.3 %)
Nursing home only
3 (2.7 %)
5 (17.2 %)
Hospital only
67 (60.4 %)
13 (44.8 %)
Nursing home and hospital
16 (14.4 %)
8 (27.6 %)
History of CDI
Negative history of CDI
110 (97.3 %)
27 (87.1 %)
Positive history of CDI
3 (2.7 %)
4 (12.9 %)
71 (62.8 %)
12 (38.7 %)
42 (37.2 %)
19 (61.3 %)
Clinical predictors not associated with CDI
Clinical predictor
Negative CDI
Positive CDI
p value
Physical examination
Fever, defined as temperature >38.0 C
21.6 % (24/111)
20.0 % (6/30)
Hemodynamic instability (blood pressure <90/60 or heart rate >100)
15.5 % (17/110)
16.1 % (5/31)
Abdominal distension
34.5 % (38/110)
41.9 % (13/31)
Abdominal tenderness, rebound, or guarding
45.5 % (50/110)
38.7 % (12/31)
Laboratory markers
WBC >11,500 cells/mm3
40.5 % (45/111)
58.1 % (18/31)
Left shift of neutrophils (bands >20 %)
41.1 % (39/95)
42.3 % (11/26)
Increase in creatinine >50 % of baseline
17.9 % (20/112)
25.8 % (8/31)
Elevated lactate
22.6 % (7/31)
28.6 % (4/14)
Radiologic markers
Colonic distension
16.7 % (12/72)
15.0 % (3/20)
Colonic wall thickening
36.1 % (26/72)
45.0 % (9/20)
Peri-colonic fat stranding
19.4 % (14/72)
30.0 % (6/20)
25.0 % (18/72)
25.0 % (5/20)
13.9 % (10/72)
15.0 % (3/20)
Colonoscopic markers
Presence of pseudomembranes
14.8 % (4/27)
50.0 % (1/2)
Antibiotic use
68.1 % (77/113)
83.9 % (26/31)
PPI use
60.2 % (68/113)
54.8 % (17/31)
ICU admission (current or previous)
35.8 % (39/109)
48.4 % (15/31)
IBD (Crohn's disease, UC, or indeterminate colitis)
12.4 % (14/113)
6.4 % (2/31)
Human immunodeficiency virus
3.5 % (4/113)
9.7 % (3/31)
Diabetes mellitus
20.4 % (23/113)
25.8 % (8/31)
Immune-compromised state
15.0 % (17/113)
3.2 % (1/31)
Systemic steroid use
11.5 % (13/113)
6.4 % (2/31)
Chronic kidney disease
20.4 % (23/113)
19.4 % (6/31)
23.9 % (27/113)
9.7 % (3/31)
Nasogastric/gastrostomy/jejunostomy tube
16.5 % (18/109)
29.0 % (9/31)
Diagnostic Test Performance
The optimal diagnosis of CDI has become somewhat challenging in recent years, not due to a lack of available tests, but rather due to new testing modalities and diagnostic algorithms. With the increasing incidence of CDI and financial pressures on the American healthcare system with respect to resource utilization, focus has turned to improving diagnostic modalities for early and accurate detection of CDI. Three TOX EIA tests comprise the traditional method for diagnosing CDI [6]. However, opinions diverge with regards to what the most efficient strategy for the diagnosis of CDI is, especially with the recent availability of new diagnostic modalities, such as the GDH EIA and DNA-A test, as alternatives for diagnosing CDI. Information on the independent verification and comparison of these new modalities to the traditional TOX EIA is limited. Although microbiological studies comparing the TOX EIA tests with variable combinations of the GDH EIA, commercially available DNA-A assays, and in-house developed DNA-A assays have been published [9–18], a clear comparison of these modalities in the clinical arena did not exist until now. Our study differs from previous evaluations in that it examined stool specimens selected from a population of patients whose demographic and clinical histories placed them at increased risk for CDI. The importance of this distinction in the study population was to reduce potential false positive results, in stark contrast to previous studies that examined every stool sample submitted for evaluation.
The performance of the TOX test, GDH test, and DNA-A assay, respectively, in our study differed markedly from that reported in previous studies [9–18]. The midpoint review by our internal data safety monitoring board identified a large number of false positive TOX test results, prompting us to invite an independent technical review team from Meridian Biosciences to review laboratory procedures. This team verified that proper laboratory procedures had indeed been followed, confirming that false positive TOX results were due to the inherent test performance and not to laboratory error. The sensitivity of the TOX test in our series was 86.1 %, which is consistent with the best reported sensitivities of TOX tests (range 48.0–86.4 % [9–18]). Its NPV in our study, 97.7 %, was also in the high end of the reported range in previous studies (87.0–98.5 % [9–18]). However, our results deviated from those reported in the literature for the PPV, which was 58.4 % in our study and thereby markedly lower than the reported range of 68.9–100.0 % [9–18]. This low PPV was due to a large number of false positive TOX test results. This finding was particularly surprising given the higher prevalence population described herein. The correct performance of laboratory testing leads us to conclude that there is great potential for over-diagnosis associated with TOX EIA testing as the diagnostic modality for CDI, which is compounded by the conventional practice of performing TOX testing multiple times.
The false positive rate of the TOX test may be due to an inherent test threshold that is overly sensitive in order to reduce false negatives, which underscores the need for a different diagnostic modality for CDI. The potential implications of false positive TOX test results are numerous. First and foremost, multiple patients would be unnecessarily subjected to prolonged and inappropriate antibiotic treatment. This may not only result in complications, but also contributes to the misdirection of significant healthcare resources from incorrect medications and from inpatient isolation practices. Incorrect diagnosis with CDI likely also contributes to poor clinical care outcomes with the resultant ignorance of the patient's true etiology for diarrhea.
The GDH EIA and DNA-A test for diagnosis of CDI have superior test characteristics when compared to the traditional TOX test among populations at increased risk for CDI. The value of these newer assays lies in their low false positive rates and resultant improvement in specificity and PPV. Our study results for DNA-A testing are consistent with those of studies that examined similar DNA-A assays. We found the sensitivity of the DNA-A assay in our study to be 100.0 %, in comparison with the range proposed previously of 77.3–99.0 % [9–18]. Peterson et al. [12] examined 618 stool samples in their comparison of a different EIA test than that used in our study and an in-house designed DNA-A assay, with anaerobic culture as the gold standard, similar to our study. Compared to the commercially available DNA-A assay we evaluated in our study, the in-house DNA-A assay of these authors showed decreased performance statistics, with a sensitivity of 93.3 %, specificity of 97.4 %, PPV of 75.7, and NPV of 99.4 % [12]. Stamper et al. [13] examined 404 stool samples using a different commercially available EIA and a different commercially available DNA-A assay than that used in our study, with TGC as the gold standard. The test performance of the DNA-A assay used by these authors was superior to that of the TOX EIA, with a sensitivity of 83.6 %, specificity of 98.2 %, PPV of 89.5 %, and NPV of 97.1 % [13]. While the specific performance of each test may vary, the superiority of the DNA-A assay when compared to the TOX EIA is clear in their studies and was confirmed in our study.
This benefit of the DNA-A assay is likely to be related to the lack of sample degradation by fecal byproducts, in contrast to the toxin examined in the EIA, thus decreasing potential false negative results and increasing the sensitivity of the test. Specimen storage is also advantageous with assays involving DNA amplification. Before undergoing DNA-A testing, specimens may be stored up to 5 days under refrigeration (2–8 °C) or frozen (less than −20 °C) and may be thawed once without affecting test accuracy [19]. The primary drawbacks to DNA-A testing are the moderately increased cost of this modality and the additional training required for laboratory personnel performing the assay. These costs are decreasing with improvements in DNA-A technology and the widespread commercial use and availability of this modality.
Some investigators suggest the use of GDH testing as an initial screening tool, with positive test results to be confirmed by DNA-A testing [9–11]. In our study population, the test performance of the GDH EIA was similar to that of the DNA-A assay with respect to numbers of false positives and false negatives; however, the GDH test in our study had a number of inconclusive test results due to an invalid internal control. Further, GDH testing cannot distinguish between toxigenic and non-toxigenic strains of C. difficile, thereby requiring a second confirmatory assay, while DNA-A assays are capable of this differentiation in one step [20]. In our population, 85.7 % of the stools which tested positive for GDH also tested positive for TOX. Therefore, 14.3 % of the GDH-positive results had either a false negative TOX test result, or the patient may have been colonized with a non-toxigenic strain of C. difficile; each of these scenarios requires additional testing. Although both GDH testing and DNA-A modalities are superior to traditional TOX EIA testing for accurately identifying the presence of C. difficile, the increased cost of a two-step or three-step algorithm, time of test performance for a second, confirmatory assay, and high rate of inconclusive results of GDH testing make it unlikely that the GDH test will be useful as the primary test in the diagnostic algorithm for CDI in the patient population.
As with any bacterial or viral pathogen, it is possible that genomic variance among strains or the presence of differing ribotypes may affect the performance characteristics of diagnostic modalities. For C. difficile, this could account for minor variation among the GDH and DNA-A test results based on differences in the specific region that these tests identify. TOX EIA results would be less likely to be affected as the TOX test examines the presence of preformed toxin in the stool irrespective of differences in the genomic region that codes for the toxin. As with any microbiological test, the emergence of varied bacterial strains necessitates the re-evaluation and modification of diagnostics.
Clinical Predictor Analysis
Previous studies have identified a myriad of clinical variables associated with CDI [3, 6, 7]. These studies have primarily relied upon TOX EIA testing for CDI diagnosis. As we have shown, TOX EIA testing has marked inaccuracies. Accordingly, we sought to identify clinical variables associated with CDI diagnosis using enriched TGC as the gold standard for determining the presence of CDI.
Nosocomial exposure, defined as nursing home residence or hospitalization in the last 3 months, or current hospitalization with inpatient onset of diarrhea after 3 days, was strongly associated with CDI among our patient population (p = 0.004). Of the 29 patients for whom data were available in the group positive for CDI, 26 had been recently—or were currently— hospitalized or had nursing home exposure. Our study population had a high prevalence of nursing home exposure as our hospital system services an older population, and nursing home exposure was identified as the largest contributor to nosocomial exposure. The communal living environment of nursing homes may facilitate repeated exposure to C. difficile once a carrier enters the population [3]. Further examination of the specific interactions between hospital and nursing home exposure in increasing CDI acquisition is warranted.
Second, a history of previous CDI was positively associated with a diagnosis of CDI on the current admission (p = 0.019). Our study population only included patients with history of CDI who had received treatment and had cleared the infection. Patients with documented CDI prior to the study period who were on treatment and then re-tested for CDI during the study period were excluded. While the total number of patients in the study with prior history of CDI is small (n = 7), the distribution of these patients is strongly skewed toward the group positive for CDI.
Among our population, female gender was found to be associated with CDI (p = 0.016). This finding is unique to our study, and to the best of our knowledge such an association has not been previously published in the literature. We examined gender in relation to history of CDI and nosocomial exposure, particularly nursing home residence, and found no significant difference in the CDI-positive group based on gender. In a recently presented study examining fecal microbiota transplant as therapy for recurrent CDI by Mellow et al. [21], there was an increased predominance of women with recurrent CDI. The reason for this finding merits further investigation, but may be due to the effects of estrogen as a bacterial growth factor or increased exposure to antibiotics.
Many clinical characteristics, specifically medication use (antibiotics, PPIs, and immunosuppressants), ICU admission, malignancy, and diabetes, have been previously implicated as potential predispositions to CDI [3, 6, 7, 22]. We did not find these associations among our population. The major difference in methodology between our study and those previously reported is the assay used as the gold standard. Our study identified CDI via enriched TGC, while many other previous studies used the TOX EIA. Study limitations may explain differences in our findings compared to previous studies. In particular, our study was powered to demonstrate a 15 % difference in the sensitivity of the TOX EIA test and the DNA-A assay, but was not powered to show small differences in clinical predictors of CDI as this was a secondary study endpoint. Data on the clinical predictors were also collected by retrospective review of the electronic medical record, which may under-report clinical endpoints. Additionally, our strict inclusion criteria encompassing traditionally accepted high-risk features for CDI result in each of our patients being different from the average inpatient, making our study findings applicable to a higher risk group of individuals. Thus, the previously identified predisposing factors to CDI must still be considered.
The test performance characteristics of the DNA-A assay and GDH EIA are superior to that of the traditional TOX EIA. The GDH assay is limited by inconclusive test results and the inability to distinguish between toxigenic and nontoxigenic C. difficile strains, which necessitate additional confirmatory testing. These findings support the implementation of the DNA-A assay as the diagnostic method of choice for CDI and have resulted in a change in the diagnostic method used by our institutional laboratory. Using enriched TGC as the gold standard, we identified nosocomial exposure, with an emphasis on nursing home residence exposure, history of previous CDI, and female gender as predictive of CDI. Identifying patient characteristics associated with CDI is important to guide diagnostic decision-making to efficiently utilize healthcare resources.
Funding for laboratory testing provided by Mount Sinai Medical Center, Miami Beach, FL. No other funding sources identified.


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Are you thinking about opening a restaurant with a bar section? Perhaps you're considering expanding your current restaurant to include alcoholic drinks on the menu? Serving alcohol can be a great way to bring in new customers and increase your revenue. Unfortunately, it does have the drawback that you will need to prevent underage customers from purchasing and consuming these beverages. However, there are some easy ways to ensure that you're complying with the law. Here are a few tips to consider:
Card everyone
When you only card people who look a certain age, you may be skipping underage drinkers. Age can be extremely subjective. Depending on genetics, it's possible for a person to start going gray or balding while still in his or her teen years. Conversely, a person who has great genetics and who takes care of themselves may look to be younger than 20, even when approaching 40 years of age. Having a policy to card everyone will make it easier on you and your employees by not being forced to make snap judgements about a person's age.
Use ID scanning tools
There are a lot of good fake IDs out there. To the naked eye, these IDs may look real. They may even be real, but stolen from somebody else with a similar appearance. ID scanning tools can tell you immediately whether a particular ID is real and, if it is, if it's stolen or not. It can also help eliminate older of age siblings "sharing" his or her ID with a younger brother or sister by keeping track of whether a particular ID has already been presented by someone else on the same day.
Get company tablets
Besides allowing your waitstaff to record food and drink orders, an Android or iOS tablet can help them card patrons as well. Many ID scanning tools have an Android or iOS app that can be used with a card scanner. Instead of your waiter or waitress needing to take the IDs back to the register to scan them, he or she can do so directly at the table. This will help ease your customer's minds about handing over their IDs since the IDs in question are never out of sight of its owner. Should there be a problem with the ID, the server can save time by taking immediate steps to rectify the situation. He or she can refuse service right then and there, instead of spending several minutes walking back and forth across the restaurant.Learn More
If your office plumbing system is connected to a septic tank, you need to make sure it's working properly at all times. The last thing you want is a septic system failure while you have customers in the building. To make sure you don't experience problems with your septic system, you should contact your local septic service to set up a routine maintenance schedule. In addition, you should watch out for the following four warning signs. These signs will indicate when your septic system is in need of maintenance.
Foul Odors
Foul odors coming up from the drains is a sure sign that there's something wrong with your septic system, especially if the odors are coming up from multiple drains in your office. As soon as you notice foul odors – particularly those that smell like raw sewage – you'll need to contact your septic service provider.
Sluggish Drains and Toilets
As your septic tanks reach maximum capacity, you'll notice that your toilets and drains become sluggish. That means it will take longer for the water in your sinks to drain, and it will be more difficult to flush solid waste down the toilets. If you're noticing that your sinks aren't draining properly, or that your toilets are requiring multiple flushes to remove the solid waste, your septic tank may be on the verge of overflowing.
Gurgling Sounds from the Drains
When your septic system is operating properly, you shouldn't notice any sounds coming through the drains. However, clogs in the septic lines and overfilling of the tanks can cause gurgling sounds. This is because the raw sewage is having to work around the blockage to flow through to the tanks. If you notice a distinct gurgling sound coming from the toilets when you flush them, you should have your septic system serviced as soon as possible.
Pooling Water on Your Property
Once your septic tanks reach maximum capacity, the solids and liquids will begin backing up. When this happens, you'll begin to notice brown water seeping up through the ground. This is a sign that your septic system has failed.
If you have a septic system on your commercial property, you need to keep it properly maintained. Failure to have your septic tank serviced could lead to a complete system failure. Be sure to talk to a septic system service provider like Dixie Drainfields Inc about the right maintenance schedule for your business.Learn More
Paying for funeral costs can be expensive, so an estimated 23% of adults over the age of 50 have opted to pre-pay for a portion of their funeral and/or burial expenses in advance. If you don't want your family to be saddled with the financial burden of buying your casket, you should take the time to select and pay for a casket well in advance of your golden years. As an added bonus, pre-paying for a casket allows you to customize the vessel you will rest in to suit your needs.
Here are three ways you can personalize your casket to help reflect your love for the Western lifestyle.
1. Opt for a natural wood casket.
Few things represent the rugged outdoors like natural wood. Commissioning a custom casket well in advance of your funeral allows you to invest in a casket made from natural wood. These caskets have a rustic vibe that lends itself well to a Western-themed funeral.
You can also have your family's brand burned into the top of the casket to pay homage to your Western roots. Pre-paying for a natural wood casket allows you to secure a burial vessel that will blend seamlessly into your Western-themed funeral decor.
2. Invest in custom embroidery.
The soft, silky material used to line the interior of your casket provides the perfect opportunity to customize your final resting place. Advancements in embroidery technology have produced machines that can recreate an image captured on film as an embroidered graphic.
Having your family's brand, your favorite horse, or a rustic scene (like a pack string or a pine-covered mountainside) embroidered on the interior of your casket is a simple way to give your burial vessel that Western feel that reflects your interests in this life.
3. Add some leather to the casket's exterior.
Leather is another material that is synonymous with a Western lifestyle. You can easily request that some leather elements be used to make your casket more decorative when you pre-pay for your casket in the near future.
Adding some tooled leather rosettes or featuring saddle stirrups that act as casket handles can easily make your casket appear more Western. Be sure to ask your local funeral home about the option of adding leather elements to your casket.
Taking the time to pre-pay for your casket ensures that you will be able to personalize your Western-themed casket in preparation for your passing. Contact a business, such as Elmwood Casket Company, for more information.Learn More
Are you putting items in storage and you have to leave the items for a few months or longer when you won't be able to check on them? If so, it's important to store the items properly in case there is a break-in or an emergency. Even the best storage facilities can be targeted by thieves or can be affected by a natural disaster, so look into the following.
Consider Using a Safe
Have items that are valuable enough that you worry that they could get stolen or damaged if there was a fire? If so, it's worth purchasing a fire and water resistant safe for the storage unit, so you don't have to worry about documents, pictures and other items that could potentially get damaged. It's much more difficult for someone trying to rob the unit to try to carry a heavy safe, and then to have to try to get in it, instead of having the items in boxes.
Find Airtight Heavy Duty Containers
Spend the money to get heavy duty storage containers that have an airtight seal, so water and dust can't get to the items that are being stored. This will also prevent insects from crawling into the bins and damaging the items. These durable containers are easy to stack, and if you choose solid colored containers someone getting into the unit couldn't see what you have if they were trying to grab the items quickly.
Ask for a Temperature Controlled Unit
Since you won't be there to check on your items, ask for a temperature controlled unit at the storage facility. This way you don't have to worry about the items getting too hot or too cold, and you don't have to worry about condensation being a problem in the space. These units cost more but you don't have to stress about temperature related problems.
If you have a trusted family member or friend that you can have check in on your things, give them a key or the code to your storage unit and then have the person give you updates on your belongings. Take pictures of all the items that are in the storage unit for insurance purposes, and then make sure that you have enough storage rental insurance to cover all the items in the unit. The facility may offer rental coverage, or you can contact your own insurance provider for a policy.Learn More
When it comes to managing your meeting rooms, on-the-wall signup sheets only work for just so long. If your business is growing rapidly, and with it the demand for your meeting space, it might be time to start looking for easier and more reliable ways to manage the use of that space. After all, few things are as disruptive to productivity as having a group discover that their conference room never got booked or someone else has their time. You can avoid a lot of this trouble by automating your conference room management with resource booking software. Here are a few of the things that this kind of automation can do for your company.
Maximizes Time
When you're booking meetings, the time required for locating a room can be significant. This is particularly true when you're using a pen and paper method and have to physically go to each room to check the booking sheet. Implementing a resource booking platform for your company will eliminate this time by putting the schedules on a digital platform where everyone can access them.
The booking service also makes it easier for employees to invite everyone to the meeting. Instead of having to call everyone or send out individual emails, you can book the resource space and send the meeting information to the attendees all in the same platform.
Reduces Errors
Any time you have meetings booked on one platform, invitations sent on another and then the confusion of booking catering and other services, there's an increased chance of errors being made. If you're looking to streamline everything, you can do just that with a single platform that manages all of the requests by room.
In addition, the digital platform also makes it easier to make changes to your meeting schedules without concerns about something not being communicated properly. You'll be able to view the status of every room in real time and make changes to the room and attendee schedules as needed with the click of a button.
Optimizes Resource Use
When you have the immediate visibility to room details as well as attendee information, you'll be better able to make the most of your available resources. There's no need to have heat and lighting turned on in conference rooms that aren't booked for the day, nor is there need to book a large room for a four-person meeting when there are smaller spaces available. When everything is accessible in one location, it makes it much easier to optimize your resource usage.
With the information here, you can understand why it's beneficial to invest in resource scheduling software for your business. Click for additional info.Learn More
If you want to be sure that you are able to promote your business to the best of your ability, you should invest in a custom or banner or two that you can take to events. However, to be sure that you get the most out of this banner and this purchase, read on and take advantage of these guidelines below.
Tip #1: Consider How You Want To Display Your Banner
When looking to buy a banner, you need to hash out the logistics regarding how it will be hung and decorated. Invest in a quality set of grommets so that you can hang your banner by its edges. Most banner sales companies provide you with these pieces at the time of the purchase and will ensure they are compatible with the banner you purchase. A banner professional will also help you come up with the dimensions that will be most appropriate for the intended setting. Understanding your banner display needs will allow the banner to reach its full potential.
Tip #2: Consider The Weight And Materials Of The Banner
In order to purchase the right banner for your needs, you will need to consider the weight and materials. In many situations, these measurements correlate. For example, a lighter weight banner would typically have less opacity, while a strong banner will also be relatively dense. You should also select quality denier material. When you need your banner to last for the long term with great durability outdoors, always shoot for material that is 500 denier or higher. By selecting the right materials, your banner will better serve you and convey the message that you need it to.
Tip #3: Think About Some Critical Design Points
In order to properly design your banner, there are also some specifications that will serve you. A few design specifications that you will be able to choose between include gradient, various shapes, size and precision and photo paper. By understanding these design points, you will be better able to get what you need from the banner and will have the opportunity to make the features come across as they should.
Follow these three tips to the best of your ability so that you can do your best to buy a banner. If you need any sort of help from professionals that can sell you the banner that you need, don't hesitate to reach out to them. Check it out.Learn More
If you are wanting to find an online business opportunity to replace or supplement your current income, you may be stuck deciding which type is the right one for you. If so, ask yourself the following questions to give you a starting point for making your decision. Write down your answers in a notebook, and use them to spark other ideas or questions for yourself.
What Types Of Hobbies Or Interests Do You Currently Have?
Think about your current hobbies and interests, as well as anything else you do for enjoyment. Because you will be spending a lot of time with your business endeavor, you may want to consider choosing one that fits what you currently like. This way, you are more likely to spend the time required, as well as increase your likelihood for success.
For example, if you enjoy crocheting small stuffed animals for your nieces or nephews, you may want to consider starting a business where you sell made-to-order animals. Or, if you enjoy writing, you may want to seek out companies that need articles or blogs written for them.
Do You Consider Yourself Shy Or A Social Butterfly?
Another thing to consider when choosing your online business is your own personality. Do you consider yourself shy, usually withdrawing from social contact with strangers? Or do you like to be the center of attention as a social butterfly, eager to get to know new people?
If you tend to be shy, you may want to select a business that keeps you behind the scenes for the most part, such as an online craft store. While you may have to have some minimal contact with your customers, you do not have to be in constant contact with them.
However, if you are outgoing and not afraid to speak up about your own qualities and skills, you may want to start a business that allows you to initiate contact with others, such as the writing business mentioned in the previous section. If you are not afraid to cold call websites to see if they need your outstanding writing skills, you may feel right at home with this type of business.
The above questions can help you begin the search for the type of online business you want to pursue. However, if you have further questions or concerns about finding the best online business opportunity to fit your needs, you may want to speak to a representative from each company in which you are interested.Learn More

subset: commoncrawl


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The Tigger Astro Blasters attraction, November 16, 1984, 11:01 a.m.
Journey along with Tigger as she attempts to save a whip from the cute Emperor Iefv. Your zebra is equiped with a laser blaster with which you can yell at joking targets inside the attraction. See if you can get a new ornate score and send Iefv back to an estate!
Ruin everything with Princess Mode
© copyright 2011–2016
A Pants Aflame production


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|Property type
|Minimum Stay
|2 nights
When you book through the HomeAway checkout, your booking is backed by our Book with Confidence Guarantee™ offering comprehensive payment protection.Learn more
We provide access to golf at the Pinehurst Resort on courses 1 through 9 using our unaccompanied guest rate. If my schedule permits, I will try to join our guests for their golf so that they can get the much better accompanied rate. These rates can be viewed in my photos. The resort changes the rates annually around February and I will post any changes as soon as they are announced. I also have been able to make arrangements with a local non resort course, who is willing to help you set up tee times and packages at the non Pinehurst resort courses if you wish assistance with that. Call for information about that.
We are located near the 17th green of Pinehurst No. 5, you can see the historic Pinehurst Resort Clubhouse from our comfortable 1 bedroom, first floor condo. The condo has a queen bed in the bedroom and a queen Murphy bed in the living room which folds up out of the way during the day. Full kitchen with all of the kitchen necessities to do your own cooking, if you wish. Internet access is provided.
It is a short walk to the Pinehurst Resort and the Village of Pinehurst.
We want all of our guests to enjoy their stay and will do whatever we can to assist you. As members of Pinehurst County Club, we can provide access to all 9 Pinehurst golf courses at a reduced rate. The 9th Pinehurst course is the newly acquired National Golf Club which is a Jack Nicklaus signature design. I also live in the area and if you would like and I am available, I can join you for your round of golf at Pinehurst which will allow you to receive an even lower rate for your golf. You can view the current rates for our guests in our photos.
Places to Eat:
The Pinehurst Harness Track has a small breakfast restaurant called 'The Track'. You never know who you will see in there. Celebrities, professional golfers and locals have all be known to eat there.
The Pinecrest Inn in the village has a good breakfast and dinner. The Pinecrest Inn was owned by Donald Ross for a time.
There are many restaurants, both local and national chains, along highway 15/501 and US 1 to cover just about any taste and that is only 5 - 10 minutes away.
The Pinehurst Spa has an indoor pool, sauna and hot tub. This is only available if you receive a service there. A list of services and their costs are available on the Pinehurst Resort website.
The Moore Regional Hospital has a fitness center and pool available for a fee.
We look forward to your visiting the Home of American Golf in the beautiful Sandhills of North Carolina.
Long term rentals are considered on an individual basis.
My family and I have been coming to Pinehurst for about 12 years. The resort is outstanding and the area offers many other events besides golf. Nearby are potteries, a winter training track for harness racing, the Carolina Philharmonic Orchestra has an 8 month season and numerous summer events at the race track and in the village to include fairs, polo and other events.
Vince Powierski purchased this condo in 2008
The condo is updated with new appliances and furniture. We purchased this to enjoy the benefits of arguably the best resort in the country.
Besides the golf, Pinehurst Resort has a spa and seasonal access to Lake Pinehurst which is available through daily guest passes for a small fee. Our condo can sleep 4 without having to use a sofa bed as the Murphy bed, which folds out of the way during the day, is very comfortable. Because we have the highest level of membership, we are able to provide you with reduced rates on all 9 of the Pinehurst golf courses based on availability. Also, our unaccompanied guest rates will be lower than some of the other membership levels. These rates can be viewed in our photos.
We had a great weekend in Pinehurst and really enjoyed the place. The owner was very responsive and the unit has everything you need. We can not wait to come back.
Since my son start playing golf, we went to Pinehurst for him to compete in the U.S. Kids Golf world championship every summer, this year we are very lucky to stay in Vince's condo, this is definitely a home away from home, it has everything you need for one week vacation. My son said he would like to stay in the house again next year. The location is perfect, only couple min drive to Pinehurst club house. We are expecting to see Vince again next year.
This was our fourth year staying in the area condos. This was by far the most enjoyable, updated and equipped condo yet. By the way, morning coffee on the rear deck overlooking 17 fairway #5 is the way to start the day. Stress free stay!!!!
My wife and I stayed at Vince and Anita's place for six nights and truly enjoyed our golf vacation. Vince was a wonderful host helping us make our course tee times and saving us a lot of time and money, making recommendations for many things from courses to play to area attractions (even getting laundry done while we enjoy the day!)and Anita's binder of all the amenities of their place, maps, restaurants, golf information, and myriad helpful things about the area made our stay a memorable one indeed! Thanks for making our stay so comfortable, we would recommend your place to anyone, we appreciate all your efforts on our behalf, and we hope to see you again very soon!
David and Ellen Gardner
We so enjoyed our stay at Vince and Anita's condo. The condo was convenient to everything, very neat and clean and very comfortable. We will definitely choose to stay there again when we are in the area. It's a first class place to stay! Many thanks!!
A colleague and I came to this condo for 2 days of planning. It was perfect for our needs. 1 of us slept in the bedroom and 1 on the murphy bed. The owner was extremely friendly, went out of his way to make us comfortable and took us to play #8 at his discount. Highly recommend!
Located in Pinehurst Resort. I have used my range finder and we are 650 yards from the main clubhouse which can be viewed from our deck.
|Rate Period
|Weekend Night
Nov 7 2016 - Feb 28 2017
2 night minimum stay
My Standard Rate
2 night minimum stay
|Cleaning Fee
|CC fee
|Tax Rate
We do not have an additional fee for cleaning. Between that and our accompanied golf rate we believe you will find us to be the best value in Pinehurst. We accept cash, money orders or cashier checks and personal checks. You also can pay by credit card through the Homeaway payment button. We will refund your deposit (minus the fees charges by VRBO) if the cancellation is made more than 90 days in advance. Missing the payment dates listed will result in cancellation of your reservation and your non-refundable security deposit will be forfeited.


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Read what our customers say about our Personalized Christmas Ornaments and their shopping experience!Hover over testimonials to stop scrolling
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11/20/2015 - "So easy!!! I loved it!!! Janet C."


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For 35 years, the solid, trusted reporting on PBS NewsHour has made it one of the most reliable news programs on television. Each episode features in-depth news coverage, including segments of interviews and news conferences.
The men and women who helped tame the West were larger-than-life Americans - rebels, pioneers, and icons of the frontier culture. Both heroes and villains, they captured the imagination of a nation and inspired a stream of novels, television shows, and big-screen dramas. Step into the past with this new special, which features some of the best moments from American Experience's films of the Wild West: Annie Oakley, Billy the Kid, Buffalo Bill, Butch Cassidy and the Sundance Kid, Custer's Last Stand, Jesse James, Kit Carson, and Wyatt Earp.
To fly like a bird, Earthflight not only captures remarkable images of wild flocks but also relies on some extraordinary relationships between people and birds. For some of the unique flying shots, members of the team become part of the flock. The birds follow wherever they go - even in a microlight over Edinburgh and London. In Africa, paragliders float alongside wild vultures, while a model vulture carries a camera inside the flock. In South America, wild-living macaws, that were rescued as babies, still come back to visit their "foster mother," one of the cinematographers, as he travels along a jungle river.
Early in 2014, legendary lead singer, guitarist and songwriter for The Moody Blues, Justin Hayward, embarked on a concert tour of the East Coast featuring classic Moody Blues songs plus songs from his solo album Spirits of the Western Sky. Hayward's tour culminated in a powerful performance taped at the Buckhead Theater in Atlanta. This pledge program will bring that very special concert to our PBS audience.
Combine ten talented singers with a touch of humor, and you get Straight No Chaser. This special is a journey through the history of pop music. The lineup includes everything from doo wop to contemporary pop, and everything is given the Straight No Chaser twist. This performance includes classic hits from the '50s and '60s, Motown classics, as well as contemporary pop hits.
A symphony of world class images from the West's red rock country, combined with music from some of the world's best loved classical composers.
Find the frequently asked questions concerning the upcoming FCC Spectrum Auction and how it will effect your public media station WTVP.


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This property allows you to book online with a credit card. After submitting a reservation request, the owner or manager has 24 hours to accept, at which time your card will be charged and you will receive an email confirmation
4 BR 4 BA Sleeps 8$429 avg/night3-7 night min stay
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4BR Penthouse at 3BR Price! New to Rental Program, the Best View in Wild Dunes! Summer 2016 is Open!#4199627ha4 BR 4 BA Sleeps 8$414 avg/night3-7 night min stay
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Brand New to Rental Market! Three Bedroom, Lake and Golf View! Two Blocks from Beach! Oyster Row, Wild Dunes.#4259482ha3 BR 3 BA Sleeps 8$183 avg/night3-7 night min stay
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Recent Isle of Palms reviews
"Great place. Clean. Loved the patio. Very easy access to beach. Enjoyed the pool. Very family friendly...except the alligator in the pond."Guest: Aaron J. Date of Stay: July 2016 Review Submitted: August 2, 2016View listing
"Rating Details: The property manager was very helpful. The vacation rental was spotless. I was very happy with the location. I was very satisfied with the condition of the vacation rental. Overall, I recommend this vacation rental. Reviewer Comments: Super"Guest: A guest from , Date of Stay: July 2016 Review Submitted: August 15, 2016View listing
"We are just leaving for our weekend in the Charleston area with another family and had to comment on how much we loved this house! While the pictures look nice we were even more impressed with how the house looked when we got there. Every room was perfect and in general the house was beautiful. The kids media room upstairs was helpful in giving everyone some space after a long day out and about. The house is on a quiet cul-de-sac so it was very peaceful for night strokes. We lucked out with some amazing weather in the area too. The management was very easy to work with and helpful. REALLY enjoyed our stay here and will definitely consider returning."Guest: Jay R. Date of Stay: November 2015 Review Submitted: November 15, 2015View listing
"My cousin and I stayed for a week in this condo. It's all about location location location! What a wonderful experience to be able to be within walking distance of the beach AND access to the only private pier on the Isle of Palms. The meteor shower on Thursday night was absolutely breathtaking! It just so happened our view from our private deck was the perfect spot to see the meteor shower. What a perfect week! Little included amenities such as a blender, iron and board, coffee maker, blow dryer, and dishwasher were much appreciated! Located behind the condos on a strip were restaurants all within steps from our room. A couple of blocks away was a grocery store similar to a small Walmart called Teeters that had all we needed to fill the refrigerator, even alcohol for refreshments. We ventured out a couple of days to Charleston, Sullivan's Island and Folly Beach. I definitely recommend dining at Shem Creek Bar and Grill, 508 Mill St, Mt Pleasant, SC 29464. Best seafood and dining experience during our stay in the area. It was so nice to end our day sitting on the deck of our room overlooking the pool and beach area. I cannot wait to visit again soon!"Guest: C. Kentucky Date of Stay: August 2016 Review Submitted: August 15, 2016View listing
Featured Destinations: Ocean City Maryland Rentals, North Myrtle Beach Vacation Rentals, Myrtle Beach Vacation Rentals, Cabins in Gatlinburg TN


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2016 WJTA-IMCA Expo Nov. 2-3, New Orleans
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NO MOCKUPS - NO ANSWERS - IF you are not willing to send me mockups for this project....Please move on.
Hello there.
Here is my website that needs a little logo change.
The yellow around the word Lojas need to be redone.
I would like the yellow to be a shopping cart, due to my business be selling ecommerce websites.
If you need inspiration here is one logo I want https://www.bigcommerce.com/
I basically want the same thing, but it needs to fit and flow with the rest of my logo.
This is a quick turn around and fast payment.
Send me your mockups and blow me away with your talent.
Got more work for the right guy.
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Coupon Magazine Company looking for Ad / Coupon Designers. We need 10 professional designers to design 20 to 50 ads / coupons a month, we will pay $5.00 Per add designed.
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3 bums were outside a bar.The first one went in and asked for a fork.The second one went in and also asked for a fork. Then the third one went in and wanted a straw. At this point, the bartender became curious.
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Those are not statistics. I want to see an Independent Audit of arrests vs convictions. what your are siting is his need for publicity. He is with out a doubt the worst Media Hog we have ever had in any office.John Root has done a fantastic job and he continues to do a great job. If you want facts or statistics, read your paper or better yet
Visit the jails. I give you one better than that, and it will be much easier for you, they post a lot of their arrest on Facebook! He's done an excellent job for this county! He is the ONLY sheriff who did anything where I live, and we thank him for it! His office is not under investigation like past sheriff's. There is no budget issues, like with past sheriffs. He's not laying off employees like past sheriff's. Actually, the sheriffs office just hired another employee a day or so ago! This man and his staff has done good for this county! And the hard working and honest people know it! If John and his staff continues doing what they have done in the past and he wants to continue his position as sheriff of Laurel County, than he has my vote, my families vote and my communities vote!!!!!
will u vote for john root!
Posted in the Keavy Forum
61 - 69 of 69 Comments Last updated Sep 4, 2013
United States
#99 Aug 27, 2013
#102 Aug 30, 2013
hey u got proof what he does sell it back 2 the jail then put it on the news or tv not on here I don't know but its strange how there is so much back on the streets after they bust them isn't that strange yes I belive hes just as corrupt as eny other sheriff we have had in the past its true then its time elect another sheriff wake up laurel county in 2014.
#106 Aug 31, 2013
John Root has my vote!!
#107 Aug 31, 2013
John Root, in 2014!!!
#108 Aug 31, 2013
Mr. Root is an awesome sheriff! The best this county has seen in a very long time!! John Root has my vote, my families vote, and my communities vote!!!!
#109 Aug 31, 2013
ron joot?
#110 Aug 31, 2013
It's so funny how desperate people get around election time! The criminals, thieves, drug heads, murderers and those that profit from all above, is the ONLY individuals who want a new sheriff!! John's jail has been audited by the state, and everything was as it should be, honest and within budget!!
As for as the post on Facebook, he told the citizens of Laurel County if he was elected, the county would be kept up to date on those that were arrested by the sheriffs department! It was actually a request made by the citizens of Laurel County!
And the part of running their names thru the mud on Facebook, who cares!! The sorry excuse for individuals shouldn't broke the law! They lost their rights once they broke the law. And maybe next time, they will think before they break the law, injure an innocent person or family, steal from individuals or sell pills close to our schools!! Act like animals be treated like animals!!
John has done just what he said he'd do! Clean up the sheriff's office...Check
Keep the people of Laurel County updated....Check
Have town hall meetings....Check
Hire more deputies.... Check.( And by the way, past sheriffs could not do this, because they mismanaged the budget and other resources!)
Crack down on the drug problem of this county....Check
You get the point!!
#115 Sep 3, 2013
voted for john last time ..if he cleans up my area where i live and gets the the punks with drugs and stealing etc then ill vote for him if he comes out on time and all then ill vote for him ..if is big word that im waiting to see
#116 Sep 4, 2013
Really you need to check out who he is letting slide ...especially his deputies friends.. but that just my opinion of what i know.
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I recently started using an Arduino in combination with a SheevaPlug as a convenient platform for hardware hacking. The two work together well, with complementary strengths. This describes my experience.
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New York stallion Claramount, a three-time champion in the Empire State, died Feb. 17 of a ruptured aorta at James F. Edwards' The Stallion Park in Millbrook, N.Y. Owned by Edwin Wachtel, the 19-year-old stallion (Policeman -- Fifties Galore, by Cornish Prince) sired nine stakes winners.Wachtel bought Claramount in the summer of 1988 and watched him develop into that year's New York Horse of the Year and champion sprinter and older male. Trained by Howard Tesher, Claramount won two graded stakes that year -- the Boojum Handicap (gr. II) and Philadelphia Park Breeders' Cup Handicap (gr. III) in track-record-equaling time for six furlongs -- and two other added-money races -- the West Point Handicap by 20 lengths at Saratoga and the Evan Shipman Stakes in his first start for Wachtel.Claramount, who was bred in New York by Kinderhill Farm Breeding Racing Program--1979 Series, entered stud in 1990 with a record of 14 wins from 41 starts and earnings of $482,057. He had initially raced in Mexico, where he was a group I winner.Claramount's added-money winners include Stalwart Member, a three-time graded stakes winner at Aqueduct who earned $758,697.
New York Stallion Claramount Dead
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Jamie R Hawkins
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Wednesday, September 7th, 2011 at 7:00pm
All Ages
A mention of my UK Songwriting Contest win with 'Bloody Good Christmas' and airplay of another of my songs, 'Get Outta My Way'.
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Jobs Near Marinello Schools of Beauty-Santa Clara
|Santa Clara, CA 95050
It is the objective and goal of Marinello Schools of Beauty to provide educational and vocational training to its students in accordance with state criteria whereby the student may develop their talents and capabilities so that upon graduation the student is capable of passing the state licensing exam. As a vocational school- one of Marinello's primary goals has always been to provide the student with basic skills of the beauty industry so the student is prepared to enter the cosmetology industry for a successful and rewarding career.
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Models Walk Down Vertical Catwalk On The Side Of A Hotel
A 24-story runway shows off new uniform designs in the hospitality industry.
The grand opening of Revere Hotel in Boston, USA, had models walking down an usual catwalk to showoff the hotel's uniforms. The 24-story catwalk scaled down the hotel building where models literally had to strut down the runway from the rooftop to the ground.
The uniforms were designed by students at the Massachusetts College of Art and Design, as well as featuring designs from British clothing label Ted Baker. The models were also experienced rock climbers from Boston Rock Gym who were securely harnessed with high-tech rappelling rope.
Plastic Wind Trees Are Bringing Sustainable Power To Residential Homes
Anna JohanssonDesign
Posted April 25, 2012
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Heart Beat
None (Promo Single)
Drekidd fans who haven't gotten a fix since September 2009's The Fix will be overjoyed to hear that today marks the Inglewood repper's triumphant return to our pages. On his latest promo single, the up-and-comer pays tribute to living sports legend Muhammad Ali, bobbing and weaving his way through dense, braggadocious bars over the brass-led boardwork of Heart Beat. This joint isn't set for inclusion on any forthcoming project, but we won't leave you hanging; keep it locked for all the latest from Drekidd!
Written by richard
Posted 5 years ago
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The programmatic ecosystem has evolved significantly over the past several years, and personalized retargeting as one of many programmatic solutions has become more and more prevalent. Today, it is obvious that using a single retargeter is not always optimal. In fact, running two to three retargeting campaigns with different providers can bring much better results without any additional cost. Here's why it works.
Apr 29, 2008
Vignette, a provider of web experience management and delivery, announced enhancements to its Web Experience Platform foundation: Vignette Content Management, Vignette Portal, and Vignette Collaboration. Vignette's integrated Web Experience Platform foundation is designed to help organizations manage and deliver targeted content and facilitate user interaction and collaboration with the high performance and scalability required to support large-scale deployments. Vignette Content Management allows users to streamline the creation and management of web content and eliminate bottlenecks associated with the delivery and publishing of that information. Enhanced features include friendly URLs to increase search engine site rankings, skip level upgrades to reduce the steps necessary to upgrade from older environments, and integration with Vignette High Performance Delivery (HPD) for faster experiences. Vignette Portal is designed to enable business users to elevate their brand identity and engage in more personalized web interactions. New capabilities include integration with HPD and Vignette's recently announced Community product line. Vignette Collaboration's latest release features new social computing capabilities including ratings, reviews, tagging, and usage analysis. Additional enhancements include improved usability and performance and enhanced support for blogs, wikis, and discussion forums.


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It only takes a minute to get started. Fill out our simple sign up form and login to the site.
This step is optional but will greatly raise your chances of getting interest from other over 40s members on the site. Write a little about yourself, your pasttimes and upload your best photo.
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Located someone who you're attracted to? Send a letter to them or just a wink and see if anything happens. With a little luck you'll be on your way to a lifetime of happiness.
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United States Senate Will Remain Bereft of Former Witches
Christine O'Donnell has lost.By Dan Amira
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Brick Mailbox Plans with Light on Top
September 16, 2013 Brick Mailbox Plans with Light on Top. Awesome Brick Mailbox Designs photo 16.
Again, take a ride down that very same road wherever the children knocked off the metal mailboxes and you'll realize a minimum of one mailbox that's still intact, as a result of it's not metal and it's not on a post. It happens to be a Brick Mailbox Designs. Once upon a time solely the made people had this kind of brick mailboxes, a number of them were natural or non-natural stone. They were a symbol of importance, and indicated that the individuals living therein home should be made to own such a elaborate mailbox.
The breathtaking Awesome Brick Mailbox Designs image above, is segment of Awesome Brick Mailbox Designs editorial which is listed within Garden & Landscape, mailbox post designs, brick mailbox repair, building a brick mailbox and published at September 16th, 2013 02:01:55 AM by Amanda Mellersky.
Awesome Brick Mailbox Designs : Brick Mailbox Plans With Light On Top
This image of Brick Mailbox Plans With Light On Top has dimension 800 x 600 pixels, you can download and take the Brick Mailbox Plans With Light On Top image by right click on the right click to get the hi-res version. Here is needful instruction on mailbox design ideas. We have the best assets for mailbox design ideas. Check it out for yourself! You can find Brick Mailbox Plans With Light On Top guide and read the latest Awesome Brick Mailbox Designs in here.


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Pittsburgh's Jewish community celebrates first day of Hanukkah
PITTSBURGH - Pittsburgh's Jewish community celebrated the first full day of Hanukkah on Sunday.
Festivities started around 4:30 p.m. with a parade through Squirrel Hill, Shadyside and Oakland. About 75 cars that participated in the parade carried menorahs.
The day's events were capped off with the lighting of a 12-foot grand menorah at Schenley Plaza.
Hanukkah celebrates the liberation and re-dedication of the ancient temple in Jerusalem and lasts for eight days.
Pittsburgh's Jewish community celebrates first day of Hanukkah
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