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This is my first designed recipe without just altering a kit from Midwest or Austin Home Brew. I brewed 12 hours ago. After 7 hours after pitching yeast, the headspace in my 6.5 gallon carboy was filled and blowing out the top of the airlock. I hurried and cut a piece of tubing, and ran it into a one gallon jug half filled with a Starsan mixture. What does anyone think of this recipe? Do you think the spices and zest were in the boil too long? Or any other recommendations would be appreciated to bring out the lemon n orange flavor! Title: CITRUS SUMMER WHEAT Brew Method: Extract Style Name: American Wheat or Rye Beer Boil Time: 60 min Batch Size: 5.5 gallons Boil Size: 3.5 gallons Efficiency: 70% STATS: Original Gravity: 1.069 Final Gravity: 1.017 ABV (standard): 6.78% IBU (tinseth): 23.25 SRM (morey): 8.39 FERMENTABLES: 6 lb - Liquid Malt Extract - Wheat (48.8%) 3.3 lb - Liquid Malt Extract - Pilsen (26.8%) STEEPING GRAINS: 2 lb - Carapils (Dextrine Malt) (16.3%) 1 lb - Caramel / Crystal 40L (8.1%) HOPS: 1 oz - Saaz (US) (AA 5.8) for 60 min, Type: Pellet, Use: Boil 1 oz - Tettnanger (US) (AA 4.8) for 45 min, Type: Pellet, Use: Boil 1 oz - Saaz (US) (AA 5.8) for 5 min, Type: Pellet, Use: Boil OTHER INGREDIENTS: 3 each - FRESH LEMON AND ORANGE ZEST, Time: 15 min, Type: Spice, Use: Boil 1 oz - CORIANDER, Time: 15 min, Type: Spice, Use: Boil 2 g - PARADISE SEEDS, Time: 15 min, Type: Spice, Use: Boil 1/2 - WHIRLFLOCK TAB , Time: 10 min, Type: Other, Use: Boil 2 g - BIOFOAM, Type: Other, Use: Bottling YEAST: Wyeast - Weihenstephan Weizen 3068 Starter: No Form: Liquid Attenuation (avg): 75% Flocculation: Low Optimum Temperature: 64 F - 75 F PRIMING: Method: CORNSUGAR Amount: 5 OZ NOTES: STEEP GRAINS 30 MINS ZEST LAST 10 MINS WITH CORIANDER AND PARADISE SEEDS puree remaining fruit (without pith) in blender. heat to sterilize on stove with 2 cups of water, cool, add to primary after the first 4 days of fermentation. 14 primary, 14 secondary, 21 bottled
I'm new to this and haven't yet dabbled with my own recipe, as much as I'd like to, but the recipe looks great and it seems like u really know ur stuff. Good luck and let us know how it works!
3 lbs is way too much crystal. When steeping grains, you are unlikely to get more than 50% efficiency. 1 ozs of Corriander seems way too much. Zest of 3 Lemons and Oranges seems alot. What does this mean "puree remaining fruit (without pith) in blender. heat to sterilize on stove with 2 cups of water, cool, add to primary after the first 4 days of fermentation." I think it will be too sweet and too busy.
i think you have a good idea on how to brew, but as others already said, you have A LOT going on in this beer. -24% of your grain bill consists of crystal malt. a good rule of thumb is to never exceed 15% unless you want a really sweet tasting beer. considering you're using wheat as your base malt, your crystal sugars will really pop out. -the yeast you plan on using is going to produce a lot of banana/clove flavors. i think these flavors will either overpower all your zests or it will mix with it and make it taste a little odd. if you'd rather focus on the flavors of your zests, i would suggest using a cleaner tasting yeast like US-05. -i personally think your beer is a little big for a wheat beer. i usually shoot for an ABV between 4-5% with my wheats. that's just my opinion though.
Have to agree with most here. It will definitely make beer and maybe you will really like it. It has a heck of a lot going on. It may be perfect for you, but to me it looks like: -9.3# is too much extract. -2# is way too much carapils -3# is way too much crystal -1 oz is way too much coriander -2 oz sounds like a lot of paradise (I don't like it so any amount would be too much for me though) -you added your citrus too early since you have boiled off all the aromatic compounds -you don't want to add whirlflock to wheat beers since you want the protein to stay in suspension -yeast choice not what you would usually go with. American ale yeast or Belgian witbier yeast would probably been good choices depending on what you were going for -Is there even more to this recipe? You mentions something about a puree but don't elaborate.
See my cheap new Keezer Build Here:http://www.homebrewtalk.com/f51/chea...keezer-224848/ Primary: 2 Row IPA Second Primary: Kolsch-like ale Keg 1: Blur Moon Keg 2: Empty Keg 3: Empty Bottled: None
I wondered about the corriander because i read some people using in for a long time in the boil and some in for just a few mins. And as soon as I added it, you could intstatly smell that above all else. Same with the paradise seeds. I think it may have been a mistake not adding them at flame out. But there is alot of good info on here. I had no idea about the 15% of the steeping grains. The puree is just the blended up fruit remaining after zesting. Taking the peal off and just having the sweet fruit pureed n added to the primary to combat how bitter the zest and hops were gonna be and to balance aroma. When I dreamed up this experiment, I had BOLD in mind lol. Ill let you all know how it turns out and what ill change.
any opinion about adding extra water to the fruit puree to try to mellow out the brew? or not use a whole lot of orange and lemon puree n use more water?
If you intend for this to be an American-style wheat, 3068 is not the right yeast to use. It's going to give you banana and clove which isn't to style. Not that you can't do it, just making sure you are aware of what you have. I think those esters and phenols might be a bit much with all the other stuff you have going on. Also, no need for crystal malt unless you are going for more of a dunkelweizen-style beer.


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12-14-2012, 10:43 PM | #1 (permalink) |
is a free agent
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Don't wanna speak too soon..
But it seems like with Lowry we just can't move the ball. We look congested wen we try to attack the rim, players don't get touches etc...
I am not saying he is bad, by no means, but could it be a case of an alpha dog? How many games he tried too much too in crunch? Damn even our D looked strong today.... WTF?? P.S it bugs me so much that we will most likely lost our draft pick for him, but in this kind of class, who knows it might not be that bad. |
12-14-2012, 10:48 PM | #3 (permalink) |
is the baby faced assassin
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Our D looked strong as much because Dallas was brutal. Great game but let's not get carried away. And don't kid yourself, this team is going nowhere unless everyone is healthy and on the same page and that includes Lowry. Hopefully with our upcoming home games/easier schedule we can get on a role and then get everyone back and it continues. And tonight our bench scored more than double the points our starters did. One of those games, enjoy it but let's not lose our heads. lol
12-14-2012, 10:49 PM | #4 (permalink) | |
is the baby faced assassin
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12-14-2012, 10:53 PM | #7 (permalink) |
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The way Lucas looked tonight makes me think that Lowry can also play very well with this team, just like he did in his first 3 games.
On the other side, I don't think Bargs will ever adapt to the kind of defensive mind we've seen. He just doesn't fit in Casey's system. And without his floor spacing, DD has to play smarter, which he did. Last edited by El Barto; 12-14-2012 at 11:09 PM. |
12-14-2012, 10:55 PM | #9 (permalink) |
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With Dallas' lineup I'm surprised they're so close to 500. Their coach is good. Bargnani and valanciunas aren't good defensively. Guys like kaman dropped 9 points in the opening quarter.
12-14-2012, 10:55 PM | #10 (permalink) |
is pounding the rock!
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we play better without Bargnani and Lowry. This isn´t an opinion, is objective. Is that you can see today and vs. Nets.
They two collapse the offensive system. Today, without them, we defend strong, we move the ball, we grabbed rebounds, all players contributed to the victory... We need changes. |
12-14-2012, 10:56 PM | #12 (permalink) | |
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Mind you, a few seasons ago BC decided to ink Turk while Marion was willing to re-sign here. Last edited by Tommy C; 12-14-2012 at 10:59 PM. |
12-14-2012, 11:21 PM | #13 (permalink) |
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Realize that there's a reason why everyone looked so good tonight.... with the exception of Ross, everyone who played big minutes was here on the team last season. They have some chemistry.
It's going to take Lowry a little while to get to know his teammates before he fits it seamlessly. |
12-14-2012, 11:28 PM | #14 (permalink) | |
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12-14-2012, 11:42 PM | #15 (permalink) |
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We were better tonight because Bargs wasnt there (we had 5 defenders instead of 4) and Caldy got to guard a very cold Fisher.
We only got 95 points. But instead of losing 134-95 , we won 95 - 74. Last edited by Raptorman; 12-15-2012 at 11:26 AM. Reason: fixed autocorrect mistake |
12-14-2012, 11:43 PM | #16 (permalink) |
effin' ineffable
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Regarding Lowry it is too soon. But I don't expect that much until the foot fully heals, and that could be a long time. He should be learning from what he sees now though. He needs to be able to trust what the rest of the team can do, as they are demonstrating, and then play within his lesser self. Playing all out with the bad foot is just going to bring more injuries. He might as well be on skates out there. If he slows down and keeps his balance and lets the ball move then he'll be fine and he can gear up for next season.
Regarding the other dud, it's not too soon. It's too late. |
12-14-2012, 11:46 PM | #17 (permalink) |
a Raps fan
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I am glad they can play like this without Bargs.. it just shows that we don't need him, I think he messes up the chemistry, with his lack of effort on defense
when a team can play this hard being 4-19 coming into the game.. it just shows that Casey is the rite guy.. I did say fire him before, but when players are still playing hard, shows the coach has not lost the room I think it also has to do with the fact that Bargnanni and Lowry are out.. and the guys that are on the court today actually like playing with each other |
12-15-2012, 12:24 AM | #20 (permalink) |
Gam zeh ya'avor
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Yes, Mavs didn't play well for whatever reason - but Raps played together on defence all night long, as a team, and Calderon wasn't such a hole, was he now?
Offensively, they still looked ridiculously predictable, relying on outside shots way too much and clearly stagnant at times. But the ball was moving better, even to no great purpose, and the guys weren't trying to go iso all the time. That, combined with the defensive effort, gave them the W tonight. |
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Pasta with tomato sauce basil and grated parmesan
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Why Do Soldiers Fight?
Throughout American history, soldiers have taken up arms, some to protect their country and democracy, others for different reasons. Princeton University history professor James McPherson offers thoughts on why soldiers fight. He's the author of For Cause and Comrades: Why Men Fought In The Civil War.
Copyright © 2005 NPR. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.
LIANE HANSEN, host:
On this Memorial Day weekend, millions of Americans will remember loved ones who served their country in the armed forces. From the ragtag farmer soldiers of the American Revolution to the highly trained and equipped troops currently deployed, men and some women have come from widely divergent backgrounds to fight for the United States. Some enlisted; others were drafted. Some were motivated by love of country; others had different reasons for serving.
Princeton University history Professor James McPherson has written about the motivations of Civil War soldiers in his most recent book, "For Cause and Comrades," and he's with us to talk about why soldiers throughout American history have taken up arms.
Welcome back to the program, Professor McPherson.
Professor JAMES McPHERSON (History Professor, Princeton University): Well, thanks for having me again.
HANSEN: Let's start with the Civil War. At the beginning, in 1861, President Lincoln declared the North was fighting to preserve the Union. The Confederate president, Jefferson Davis, said the South was fighting to establish their right to secede from the Union and govern themselves without Northern interference. Is this what the regular men in the field were fighting for?
Prof. McPHERSON: Pretty much, yes. I think so. And that was the meaning of the word `Cause' in my book "For Cause and Comrades." Northern soldiers enlisted to defend the United States from the attempt to break it up. They also rushed to enlist to defend the flag, which had been fired on by the Confederate forces at Ft. Sumter. So they were fighting for flag and country. And I think the same thing would be true of the Confederate soldiers because once the Confederacy was a going concern, the Southern soldiers who enlisted to fight in its defense were fighting for their country and for their flag, as well.
HANSEN: How do you know that?
Prof. McPHERSON: I know that from the letters of the soldiers that I read, thousands of letters from hundreds of soldiers over the entire four years of the war. And they're filled with patriotic affirmations, and in some cases highly ideological motivation, especially in the case of Northern soldiers. In the case of the Confederate soldiers, as the war went on, there was another very powerful motive added: And that was to defend their nation, their country, their state, their home and hearth from invasion by enemy troops, because most of the war was fought in the South.
HANSEN: Did motivations change after the Emancipation Proclamation of 1863?
Prof. McPHERSON: Well, they did change, although that change was coming from almost the beginning of the war. They were convinced--most Northerners were convinced that while they were fighting to defend the Union and not necessarily to abolish slavery, the initial reason for the secession of the Southern states and the creation of the Confederate States of America was to defend slavery from the anticipated threat to the survival of that institution by Lincoln's election.
HANSEN: What about other wars of the 19th and 20th century. Are there times when soldiers seem to be fighting for something other than what their leadership said they were fighting for?
Prof. McPHERSON: Well, I think that once soldiers are in the Army and are facing combat, there's another kind of motive that becomes added onto whatever ideological or patriotic motives brought them into the Army in the first place, and that is indicated by second word in the title of my book, `Comrades.' There's a kind of bonding that takes place within military units, especially that when they face a common danger, that motivates soldiers to fight so--because they don't want to let their buddies down, and they don't want to lose face in the eyes of their buddies. If they run away, if they abandon their buddies, if they prove themselves to be a coward, they will never be able to hold up their heads again. So that there's kind of a bonding and unity within the unit that is a powerful factor I think for soldiers in all wars.
HANSEN: Are historians now looking at the current conflict in Iraq and doing that same sort of study on motivation?
Prof. McPHERSON: Well, I think it's probably too soon for historians to be looking at that, but certainly the Army itself is concerned about this. Army psychologists, Army officers are intensely concerned about soldier motivation in a war like Iraq, especially since that's being fought several thousand miles away from American shores for reasons that may not be clear to many of the soldiers, so there's a real problem.
There was a problem in Vietnam. And that really caused an intense re-examination of soldier motivation. Of course, most of the men who fought in Vietnam were draftees. They didn't want to be there. They didn't understand, in many cases, why they were there. The normal term was a year, and then replacements would come in individually, and they wouldn't have this kind of bonding with the rest of the men in the unit because they didn't even know the rest of the men in the unit. And so Army officers and Army psychologists are intensely concerned about this. I think it'll take a few years' perspective for historians, who might then have access to some of the letters or e-mails. I'm not sure how you're going to study when people don't write letters so much, but make telephone calls and send e-mails.
HANSEN: James McPherson is a professor of history at Princeton University and the author of many books, including "For Cause and Comrades: Why Men Fought in the Civil War." Thanks a lot for joining us.
Prof. McPHERSON: You're welcome. Thank you.
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how much does anglo eastern pay per year after training,
as an officer of the watch or third officer?
Best bet is to ask them as we can only give guesses. They will have a payscale somewhere with a description of how much each rank gets depending on years in Rank.
He's not the messiah, he's a very naughty boy!
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1936 Cord Westchester, A 25 year old ground up restoration that is ready to drive . Engine, transmission, front axel rebuilt, new wiring and new upholstery.... More
1936 Cord 810 Phaeton, This car is a really nice older restoration that was once a Classic Car Club National First when it was... More
1936 Cord Westchester, 20 year old resoration. Engine rebuilt in 2004. Richardson front end components installed. Leather redone in correct pattern. Wind wings. A... More
Cord 1937 Beverly, very good condition, restored and owned by NASCAR 5 time champion Jim Reed, original green exterior and interior, bustle back trunk,... More


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- Herstellung eines Phaffia rhodozyma : Stamms mit verstärkter Astaxanthin-Synthese über gezielte genetische Modifikation chemisch mutagenisierter Stämme (2014)
- Ziel dieser Arbeit war es erstmals durch eine Kombination aus chemischer Mutagenese und gezielter genetischer Modifikation (hier: "metabolic engineering") einen Phaffia-Stamm herzustellen, welcher über die Mutagenese hinaus über eine weiter verstärkte Astaxanthin-Synthese verfügt. Die von "DSM Nutritional Products" bereitgestellten chemischen Mutanten wurden analysiert und über einen Selektionsprozess auf Pigmentstabilität und Wachstum hin optimiert, da die Stämme aus cryogenisierter Dauerkultur starke Pigmentinstabilitäten und ein verzögertes Wachstum aufwiesen. Über eine exploratorische Phase wurde die Carotinoidsynthese analysiert und festgestellt, dass in den Mutanten keine Einzelreaktionen betroffen sind, welche für die Heraufregulierung der Carotinoidsynthese in den Mutanten verantwortlich sind. Hierbei wurden Limitierungen identifiziert und diese durch Transformation von Expressionsplasmiden mit geeigneten Genen aufgehoben, um damit eine noch effizientere Metabolisierung von Astaxanthin-Vorstufen hin zu Astaxanthin zu erreichen. Eine Überexpression der Phytoensynthase/Lycopinzyklase crtYB resultierte in einem gesteigerten Carotinoidgehalt bei gleichbleibendem Astaxanthin- Anteil. Durch eine zweite Transformation mit einer Expressionskassette für die Astaxanthin-Synthase asy konnte der Carotinoidgehalt weiter gesteigert und zusätzlich eine Limitierung der Metabolisierung von Astaxanthin-Vorstufen behoben werden, sodass die Transformante nahezu alle Intermediate der Astaxanthinsynthese zu Astaxanthin metabolisieren konnte (Gassel et al. 2013). Es konnte gezeigt werden, dass auch in den Mutanten, aus Experimenten mit dem Wildtyp bekannte, Limitierungen identifiziert und ausgeglichen werden konnten.
- Investigation of the biosynthesis of bacterial natural products (2014)
- Natural products (NPs) have been a rich source for pharmaceutically used anti-infectives and other drugs. However, the application of anti-infectives inevitably causes the development of resistant and multiresistant pathogens, which have to be treated with novel anti-infectives. The industrial research for novel anti-infectives has been concentrating on members of the bacterial Actinomycetales for a long time. Due to several reasons, e.g. the rediscovery of already known NPs, pharmaceutical companies abandoned their NP-research and focused on drug development based on combinatorial chemistry. However, the limited structural diversity of merely synthetic compound libraries has not been a fruitful source for bioactive compounds. Hence the discovery of novel bioactive NPs as a source for anti-infectives is still of economical and humanitarian interest and will remain to be an important branch of research in the future. One strategy to circumvent the rediscovery of bioactive NPs is the analysis of yet unexplored bacterial taxa. Based on this assumption, this work aimed at the discovery of novel NPs from the entomopathogenic bacterial genera Xenorhabdus and Photorhabdus and other promising taxa, as well as the investigation of their biosynthesis. ...
- Lateralization of Travelling Wave Response in the Hearing Organ of Bushcrickets (2014)
- Travelling waves are the physical basis of frequency discrimination in many vertebrate and invertebrate taxa, including mammals, birds, and some insects. In bushcrickets (Tettigoniidae), the crista acustica is the hearing organ that has been shown to use sound-induced travelling waves. Up to now, data on mechanical characteristics of sound-induced travelling waves were only available along the longitudinal (proximal-distal) direction. In this study, we use laser Doppler vibrometry to investigate in-vivo radial (anterior-posterior) features of travelling waves in the tropical bushcricket Mecopoda elongata. Our results demonstrate that the maximum of sound-induced travelling wave amplitude response is always shifted towards the anterior part of the crista acustica. This lateralization of the travelling wave response induces a tilt in the motion of the crista acustica, which presumably optimizes sensory transduction by exerting a shear motion on the sensory cilia in this hearing organ.
- pH- and sodium-induced changes in a sodium/proton antiporter (2014)
- We examined substrate-induced conformational changes in MjNhaP1, an archaeal electroneutral Na+/H+-antiporter resembling the human antiporter NHE1, by electron crystallography of 2D crystals in a range of physiological pH and Na+ conditions. In the absence of sodium, changes in pH had no major effect. By contrast, changes in Na+ concentration caused a marked conformational change that was largely pH-independent. Crystallographically determined, apparent dissociation constants indicated ∼10-fold stronger Na+ binding at pH 8 than at pH 4, consistent with substrate competition for a common ion-binding site. Projection difference maps indicated helix movements by about 2 Å in the 6-helix bundle region of MjNhaP1 that is thought to contain the ion translocation site. We propose that these movements convert the antiporter from the proton-bound, outward-open state to the Na+-bound, inward-open state. Oscillation between the two states would result in rapid Na+/H+ antiport.
- Genetic diversity and geneflow between Arctic and Antarctic populations of the lichen Cetraria aculeata along the Andes and the Rocky Mountains (2014)
- Lichens are present in most land ecosystems, frequently occupying habitats where few other organisms are able to survive. Their contribution to the ecosystems in terms of biomass and ground cover increases with latitude and altitude, being, together with bryophytes, the most conspicuous component of alpine and polar landscapes. Whereas some polar lichens have reduced distributions and are restricted to high latitudes, most of them have very wide distributional ranges, which oven extend over several climatic regions. Many of them are common to Polar Regions of both hemispheres, a distributional pattern that has been denominated as bipolar, antitropical or amphitropical. Bipolar distributions are not exclusive to lichens, but common to many groups of organisms. The bipolar element in lichens is exceptional as it includes a large number of species, while in most other land organisms it includes genera or families but very seldom species. In this dissertation I use the bipolar lichen Cetraria aculeata to give a first insight into the phylogeography of this biogeographic element in lichens. I discuss how and when the disjunct distribution of C. aculeata came to be, and try to partial out the roles that historical and ecological processes played in shaping its distribution. Sampling was designed to cover a wide geographic extension. The main e"ort was made to collect in boreal, temperate and tropical mountain ranges in North and South America, as well to include Mediterranean populations in which specimens with deviant morphologies are observed. I found that Cetraria aculeata forms a genetically congruent taxon. Although whether it should include C. muricata remains unsolved, I excluded all specimens identified as the latter from our analyses. Thee populations of both algal and fungal symbionts have a strong geographic structure. The study of the lichen fungus suggested that the species originated in the Eurasian continent and later expanded to acquire its current distribution during the Pleistocene. The results showed that all American populations originated from an ancestral population, more similar to the extant Arctic populations than to the Mediterranean ones. The comparison between the structure of fungal and algal populations showed a high degree of coherence between them. However, the similarity in photobiont use between Arctic and Antarctic populations suggests that photobiont use responds not only to a history of codispersal in vegetative propagula, but it is also a result of a selective process related to climate. Since this climatic pattern of similarity is also found in the community of Alphaproteobacteria associated with C. aculeata, we concluded that lichens might be able to accommodate or to respond to different environmental conditions by selectively associating with different symbiotic partners. Lastly, we found the Mediterranean populations of C. aculeata to be genetically differentiated in algal and fungal symbionts from the rest of the populations. While we found no grounds to believe that the overgrown morphs encountered in the region are due to the association with different algal lineages, I believe that a switch in photobiont use might be responsible for the pattern of genetic isolation encountered. Furthermore, I suggest that the Mediterranean and bipolar C. aculeata could be two different species, since both are ecologically, genetically and at least in part morphologically divergent.
- Transcriptome data reveal Syndermatan relationships and suggest the evolution of endoparasitism in Acanthocephala via an epizoic stage (2014)
- The taxon Syndermata comprises the biologically interesting wheel animals ("Rotifera": Bdelloidea + Monogononta + Seisonidea) and thorny-headed worms (Acanthocephala), and is central for testing superordinate phylogenetic hypotheses (Platyzoa, Gnathifera) in the metazoan tree of life. Recent analyses of syndermatan phylogeny suggested paraphyly of Eurotatoria (free-living bdelloids and monogononts) with respect to endoparasitic acanthocephalans. Data of epizoic seisonids, however, were absent, which may have affected the branching order within the syndermatan clade. Moreover, the position of Seisonidea within Syndermata should help in understanding the evolution of acanthocephalan endoparasitism. Here, we report the first phylogenomic analysis that includes all four higher-ranked groups of Syndermata. The analyzed data sets comprise new transcriptome data for Seison spec. (Seisonidea), Brachionus manjavacas (Monogononta), Adineta vaga (Bdelloidea), and Paratenuisentis ambiguus (Acanthocephala). Maximum likelihood and Bayesian trees for a total of 19 metazoan species were reconstructed from up to 410 functionally diverse proteins. The results unanimously place Monogononta basally within Syndermata, and Bdelloidea appear as the sister group to a clade comprising epizoic Seisonidea and endoparasitic Acanthocephala. Our results support monophyly of Syndermata, Hemirotifera (Bdelloidea + Seisonidea + Acanthocephala), and Pararotatoria (Seisonidea + Acanthocephala), rejecting monophyly of traditional Rotifera and Eurotatoria. This serves as an indication that early acanthocephalans lived epizoically or as ectoparasites on arthropods, before their complex lifecycle with arthropod intermediate and vertebrate definite hosts evolved.
- Novel three-dimensional in vitro models of ovarian endometriosis (2014)
- Background: Endometriosis is characterized by the presence of functional endometrial tissue outside of the uterine cavity. It affects 1 in 10 women of reproductive age. This chronic condition commonly leads to consequences such as pelvic pain, dysmenorrhea, infertility and an elevated risk of epithelial ovarian cancer. Despite the prevalence of endometriosis and its impact on women's lives, there are relatively few in vitro and in vivo models available for studying the complex disease biology, pathophysiology, and for use in the preclinical development of novel therapies. The goal of this study was to develop a novel three-dimensional (3D) cell culture model of ovarian endometriosis and to test whether it is more reflective of endometriosis biology than traditional two dimensional (2D) monolayer cultures. Methods: A novel ovarian endometriosis epithelial cell line (EEC16) was isolated from a 34-year old female with severe endometriosis. After characterization of cells using in vitro assays, western blotting and RNA-sequencing, this cell line and a second, already well characterized endometriosis cell line, EEC12Z, were established as in vitro 3D spheroid models. We compared biological features of 3D spheroids to 2D cultures and human endometriosis lesions using immunohistochemistry and real-time semi-quantitative PCR. Results: In comparison to normal ovarian epithelial cells, EEC16 displayed features of neoplastic transformation in in vitro assays. When cultured in 3D, EEC16 and EEC12Z showed differential expression of endometriosis-associated genes compared to 2D monolayer cultures, and more closely mimicked the molecular and histological features of human endometriosis lesions. Conclusions: To our knowledge, this represents the first report of an in vitro spheroid model of endometriosis. 3D endometriosis models represent valuable experimental tools for studying EEC biology and the development of novel therapeutic approaches.
- Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification (2014)
- Ribosome heterogeneity is of increasing biological significance and several examples have been described for multicellular and single cells organisms. In here we show for the first time a variation in ribose methylation within the 18S rRNA of Saccharomyces cerevisiae. Using RNA-cleaving DNAzymes, we could specifically demonstrate that a significant amount of S. cerevisiae ribosomes are not methylated at 2′-O-ribose of A100 residue in the 18S rRNA. Furthermore, using LC-UV-MS/MS of a respective 18S rRNA fragment, we could not only corroborate the partial methylation at A100, but could also quantify the methylated versus non-methylated A100 residue. Here, we exhibit that only 68% of A100 in the 18S rRNA of S.cerevisiae are methylated at 2′-O ribose sugar. Polysomes also contain a similar heterogeneity for methylated Am100, which shows that 40S ribosome subunits with and without Am100 participate in translation. Introduction of a multicopy plasmid containing the corresponding methylation guide snoRNA gene SNR51 led to an increased A100 methylation, suggesting the cellular snR51 level to limit the extent of this modification. Partial rRNA modification demonstrates a new level of ribosome heterogeneity in eukaryotic cells that might have substantial impact on regulation and fine-tuning of the translation process.
- Identification and Biosynthesis of a Novel Xanthomonadin-Dialkylresorcinol-Hybrid from Azoarcus sp. BH72 (2014)
- A novel xanthomonadin-dialkylresorcinol hybrid named arcuflavin was identified in Azoarcus sp. BH72 by a combination of feeding experiments, HPLC-MS and MALDI-MS and gene clusters encoding the biosynthesis of this non-isoprenoid aryl-polyene containing pigment are reported. A chorismate-utilizing enzyme from the XanB2-type producing 3- and 4-hydroxybenzoic acid and an AMP-ligase encoded by these gene clusters were characterized, that might perform the first two steps of the polyene biosynthesis. Furthermore, a detailed analysis of the already known or novel biosynthesis gene clusters involved in the biosynthesis of polyene containing pigments like arcuflavin, flexirubin and xanthomonadin revealed the presence of similar gene clusters in a wide range of bacterial taxa, suggesting that polyene and polyene-dialkylresorcinol pigments are more widespread than previously realized.


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Would you like to make this the year you started exercising regularly? At DietDoctor, we've invited an expert to guide you through the plethora of exercise advice and workout suggestions out there.
Jonas Bergqvist is a licensed physiotherapist who's worked with dietary, exercise and lifestyle coaching for many years. He currently runs a combined health and education centre with courses in, among other things, LCHF and paleo dietary advice. He's also a popular diet guru and has written several diet and exercise books, including (in Swedish) "LCHF and Exercise".
Right here at DietDoctor, he'll be publishing a series of guest posts to inspire you to get in better shape, better health… And perhaps even get that future dream body!
Guest Post
It's the beginning of the year and papers are full of headlines with speedy get-started-now-tips: This is how you start exercising! How to get a flat stomach! Build muscle! Lose weight!" Continue Reading →


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How did a single image of Che Guevara come to sell sunglasses, ice-cream and even lip balm? Peter Preston finds out more at the Victoria & Albert Museum.
They call him the the new Che Guevara. Loved and loathed in equal measure, Venezuela's President Hugo Chávez has become the poster boy of the international left, revered by his disciples at home but reviled in Washington. On the eve of Chavez's visit to Britain, foreign affairs editor Peter Beaumont travels to Caracas and asks if the Castro-loving, Bush-hating, head of state is a revolutionary democrat or a dictator in the making?
Obituary: Che Guevara's guide to a language of Africa.
Thierry Henry was clad in a T-shirt of the Argentinian communist as he was pipped to the World Footballer of the year award by Ronaldinho.
Aleida Guevara, daughter of the legendary revolutionary Che, today denounced the use of her father's image to sell 'capitalist' goods, claiming his legacy should only be used where it serves to inspire others.
The Guevara film's success is giving hope to the village where he died.
The stunning cinematography of The Motorcycle Diaries, a film about the young Che Guevara's life-changing road trip through Argentina, Chile and Peru in 1952, has inspired an increased interest in South America as a holiday destination.
Film of the week: The story of a trek that shaped Che Guevara's ideals has given Walter Salles his best movie yet
A 305-page memoir, presented in Havana, Cuba, offers rare black-and-white shots from the Guevara family album of Che in his mid-30s disguised as a balding old man with crooked teeth with his wife Aleida March de la Torre.
The revolutionary spirit lives on - at least for Walter Salles, whose Motorcycle Diaries, one of the hot tips for the Palme d'Or, was screened at the Cannes film festival yesterday.
Terrence Malick is about to begin production on his biopic of Che Guevara, starring Benicio Del Toro as the revolutionary icon.
Fifty years ago, Alberto Granado travelled across Latin America on a motorbike with Che Guevara - a journey that has now become a film, The Motorcycle Diaries. He relives the trip of a lifetime with Geoffrey Macnab.
The Motorcycle Diaries, an account of Che Guevara's 1952 tour of Central America, has garnered the seal of approval from the revolutionary's surviving family.
August 28: Ana Guevara became the first Mexican woman to win a world title when she completely outclassed the 400m field.
Reclusive legend in line to direct biopic of revolutionary leader
May 5: Faced with competing before a capacity crowd expecting only one thing, Cathy Freeman might have felt transported back to Sydney 2000 - except that this time she was not the object of patriotic hysteria.
Zoe Williams: Madonna's attempt to appropriate Che Guevara to flog her latest single is truly beyond parody.
His face adorned the T-shirts and posters of a student generation. Even 35 years after his death Che Guevara remains an icon. But to his daughter Aleida he is the mysterious visitor who gave her sweets. By Angelique Chrisafis.
At 25, Che Guevara, a newly qualified doctor, set off through Central America. The journey was to transform him from feckless tourist to fearless revolutionary, as these exclusive extracts from previously unpublished letters and journals reveal
Ebullient Cuban photographer whose portrait of Che Guevara became an icon for a generation of protest
HIS remarkable photograph of Che Guevara became an icon for revolutionaries everywhere. When Alberto Korda pointed his Leica camera at the bearded Latin American freedom fighter, he unwittingly created an image that became a legend of the twentieth century.
Robert Redford is to executive produce a biopic based on the journal which Che Guevara kept while on a journey around South America as a young student
For once in his life Gavin Turk, founder member of the Britart pack, whose creations include images of himself as Marat, Sid Vicious and Che Guevara, was both at a loss for words and quite unsure whether he was being a work of art or not.
Using dead celebrities has always been popular in advertising, but a recent case involving an image of Che Guevara has exposed the pitfalls.
The Cuban photographer responsible for an iconic image of the Latin American revolutionary Che Guevara has won his battle to assert copyright over the work.
A photographer whose shot of Che Guevara was used in an ad has won substantial damages from Lowe Lintas. By Claire Cozens.
The photographer responsible for an iconic image of the Cuban revolutionary Che Guevara has won his battle to assert copyright over the work.


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Burnley Football Club
- Nickname:Clarets
- Founded:1882
- Manager:Sean Dyche
- Ground:Turf Moor
- Capacity:22546
- Last Game: 21-Feb-2015 15:00
- Chelsea1
Burnley1 - Full match report
Clarets eye legal challenge
09 Aug 2007 - 12:30:37
Burnley chairman Barry Kilby is threatening to take legal action against the Premier League over parachute payments to relegated clubs.
Kilby is objecting to the fact that Charlton Athletic, Sheffield United and Watford will have an additional £6.8million to utilise this season, following their demotion last term.
He told Radio Lancashire: "I will be campaigning this autumn for us to bring this to court. It's a good, strong case.
"I honestly feel that it's an illegal subsidy from the Premier League that distorts our competition so badly.
"Our next step will be to bring it to the League's attention. I would like to see what the League is going to do about it and discuss it with the other clubs."
Related Burnley News
Related Burnley News


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The X Factor Review: Oh The Drama
The Top 24 was revealed on Wednesday's The X Factor. Was that the most dramatic moment of the episode?
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shinnyboots65 Posted:
the set-up on the lift was very simple. it works great, would highly recommended it to anyone that service's their own bikes


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This review speaks to their customer service, which we found virtually non existent. Do not entrust your holiday with Tremblant Sunstar. We had booked and paid for our 4 day break over the upcoming family day. In fact Sunstar had just sent out their two week reminder email confirmation outlining our obligations and financial penalties for cancellation. We have just... More
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US 4423965 A Abstract An elongated clock includes a pair of adjacent, cylindrical, rolls providing one roll with five minute segments indicated and a second roll with twelve hours of morning and evening indicated. These rolls are mounted about a shaft connected with a constant speed motor which rotates the minute cylinder at a constant rate. A gearing arrangement at the end of the shaft couples the shaft with the roll indicating hours and turns the hour roll once every hour. A segmented drive gear is coupled to the shaft and includes a pair of teeth which engage a pinion which in turn has every tooth meshing with a gear attached to turn the hour roll. Thus, one complete rotation of the shaft produces one-twelfth of a full rotation of the hour roll. The pinion gear is prevented from overriding after indexing because a locking rim of the segmented drive gear nestles into gear teeth extensions of every other tooth of the pinion gear.
Claims(7) 1. A clock having an elongated body with segmented rotating members adapted to display the time, the improvement comprising:
a drive motor coupled to a shaft and disposed to turn the shaft at a constant speed; a first time indicating roll cylinder having a length greater than its diameter and having twelve divisions, each division having a time interval indicated thereon and displaying minutes of an hour in words and also having means coupled to said shaft and adapting the first roll to rotate constantly in unison with the shaft; a second time indicating roll having a length greater than its diameter and mounted for rotation about said shaft and also having twelve divisions, each division having a time interval indicated thereon and displaying the hours of one to twelve in words; a drive gear means located at one end of the elongated body coupled with said shaft and adapted to produce rotation of the second roll; pinion gear means adjacent the drive gear and engageable with said drive gear; said second time indicating roll for displaying hours also having gear means associated therewith and said gear means being mounted to move in response to movement of said pinion gear to rotate the second roll; said pinion gear having teeth formed about its periphery, said teeth engageable with said gear means and with the drive gear whereby one complete rotation of the drive gear produces indexing of the pinion gear and only partial rotation of the gear means and second, time indicating roll, elongated housing means encapsulating the first and second cylinders and having bearings to mount and receive each end of said shaft to permit rotation of the shaft for turning said cylinders to display the time. 2. The clock according to claim 1 and:
said drive gear means having two drive gear teeth and a rim extending about its periphery; said pinion gear having teeth extensions adapted to be nestled about a portion of said rim after indexing of the pinion gear by the drive gear to thereby prevent movement of the pinion gear and the gear means which is connected with said second time indicating roll to prevent accidental and inadvertent movement of the second, time indicating roll. 3. The clock of claim 1 wherein:
said first time indicating roll includes a plurality of time indicating segments; said time indicating segments having visual means which display minute intervals; said second time indicating roll including twelve time segments to indicate hours; indicating means located between said first and second rolls for associating the minutes and hours to display the time. 4. The clock of claim 1 and said housing means including:
a cylindrical, transparent housing surrounding said first and second rolls; mounting members with means attached at each end of said cylindrical housing and including mounting and attaching means for affixing the clock to a stationary object. 5. The clock of claim 4 wherein said mounting members include:
enlarged elbows having a first opening to receive an end of said transparent housing and having a second opening; mounting plate member located in the second opening of the elbow and having openings for attaching the clock to a vertical surface. 6. The clock of claim 1 and:
said drive gear means having two teeth for intermittently driving the pinion gear and said pinion gear means having eight teeth and being adapted to be driven by the drive gear means and to mesh with the drive the gear means attached to the second roll. 7. The clock of claim 1 and said shaft having an extension for manually adjusting the time by rotating said first and second rolls.
Description (1) Field of the Invention This disclosure pertains to clock mechanisms and in particular to a mechanism for operating a so-called tube type or cylindrical clock having a pair of internal rotating members, one which indicates minutes in five minute segments and the other which indicates hours in twelve segments. (2) Description of the Prior Art A number of gearing mechanisms have evolved over the years to drive clocks ranging from pendulum clocks to modern day digital read out clocks. However, it is believed that this is the first such clock provided which displays minutes and hours on rolls adjacent one another in such a fashion that the minute rolls index every five minutes and produce a corresponding, indexing or rotation of the hour indicating roll once per hour. The prior art does not show clocks having the unique gearing arrangement provided herein which not only indexes the hour roll on an hourly basis, but also prevents override or slippage of the hour roll once the indexing has occurred. This disclosure pertains to a clock, having cylindrical, internal roll members mounted within a larger, transparent cylinder. More specifically, the internal roll members consist of a larger elongated roll divided into twelve segments with six segments indicating five minute intervals after the hour and six segments indicating five minute intervals before the following hour. A second roll is mounted adjacent to the minute roll and is likewise divided into twelve segments, each representing an hour of the day. As the minute roll rotates indicating five minute intervals after the hour, the hour roll remains in place. When the minute roll reaches a point where it indicates five minute intervals before the following hour, then the hour roll indexes to the next hour. An indicator is positioned on the outer cylinder to show the minutes and corresponding hours. A constant speed, battery powered motor is located at one end of the cylinder and is coupled with a drive spindle shaft which extends the full length of the clock. At the end of the shaft opposite the drive motor is located a gearing arrangement including a drive gear coupled directly to the shaft and including only two teeth. A pinion gear is located adjacent the drive gear and includes eight teeth. Every other tooth extends the full width of the pinion and is adapted to function in conjunction with a rim of the drive gear to prevent override of the hour roll as it turns. The full complement of eight teeth on the pinion gear mesh with the two teeth of the drive gear and also mesh with a gear attached to rotate the hour roll. Thus, one rotation of the drive gear produces only a partial rotation of the pinion gear and a corresponding one-twelfth rotation of the hour indicating roll. The drive gear has a rim having a top part located in the same plane around the perphiery as the top of the two gear members. The rim fits within the odd numbered teeth of the pinion. After the two teeth of the drive gear pass the pinion, the rim member nestles within the full length teeth of the pinion to prevent further rotation of the pinion and thus prevent slippage or override during operation of the clock. It is thus an object of this disclosure to provide an elongated, cylindrical clock member having a pair of adjacent segments to indicate the hours and minutes of a day. Yet another object of this disclosure is to provide an elongated clock member with a drive gear mechanism comprising a segmented gear adapted to engage a pinion member once every revolution and move the pinion member thirty degrees or one-twelfth of a complete revolution to thus change the hours in advancing fashion. It is yet another object of this disclosure to provide a drive gear and associated pinion having a rotation control mechanism which prevents override or slippage of the driven cylinder by providing a rim portion to the drive gear which nestles within extended teeth of the pinion after the pinion is rotated. Thus, when the clock is manually adjusted at a relatively high rate of speed, there is no override of the hour cylinder because of this motion control feature. These and other objects of the disclosure will become apparent to those having ordinary skill in the art with reference to the description, drawings and appended claims. FIG. 1 is a pictorial illustration of the clock; FIG. 2 is a sectional view taken generally along lines 2--2 of FIG. 1; FIG. 3 is an enlarged view of the right, internal end of the clock shown in FIG. 2; FIG. 4 is a partial sectional view taken generally along lines 4--4 of FIG. 3; and, FIG. 5 is a sectional view taken generally along lines 5--5 of FIG. 3. Referring now to the drawings and in particular to FIG. 1, there is shown pictorially the visual aspects of the clock disclosed herein. The clock is designated generally by the numeral 10 and includes a pair of support knees 12 located at each end. Essentially, the support knees have openings to receive a large, outer tube 14. The other end of each support knee 12 is closed off with cover plates 13 which have openings therein to allow the clock to be mounted on a flat, horizontal surface or mounted along a wall in a horizontal or vertical fashion. The tube 14 is a transparent, cylindrical member having a time indicator ring 15 and indicator 15a on its outer periphery and closed off at the right end as shown in FIG. 2 by a so-called tube flange 16. The tube flange 16 is stepped to fit partially within the tube 14 and yet provide an outer surface that will contact an internal stop 17 in the support knees 12 to prevent the tube 14 and tube flange 16 from being inserted too far into the knee 12 so that it becomes stuck. Two tube flanges 16 are contemplated as being identical members and are located at each end of the tube 14. Hour roll 19 and minute roll 21 are located within tube 14 and rotate on shaft 22. Drive spindle flanges 18, 18a close off each end of the hour roll cylinder 19. Minute flanges 20 close off each end of the minute cylinder or roll 21. It is contemplated that the rolls 19 and 21 are thin, cylindrical members formed of polyvinyl chloride (PVC). Flanges 18, 18a and 20 can also be cast from plastic. As shown in FIG. 2, the rolls 19 and 21 are mounted about the elongated shaft 22. Shaft 22 has an extension 23 for manually setting the time. The minute flanges 20 are attached to the shaft 22 and move in unison therewith. On the other hand, the drive spindle or hour flanges 18, 18a do not move in unison with the shaft 22. The outside drive spindle flange 18a has a gear 24 adjacent thereto which may be formed integrally therewith or as a separate part and then inserted therein and with a force fit or adhesive to prevent relative movement between the two members. The gear 24 has twenty-four teeth. A smaller, pinion gear 26 is mounted on a pinion shaft 27 (FIG. 2) and has eight teeth which mesh with the twenty-four teeth of the gear 24. A segmented drive gear 28 has only two full teeth and is mounted at the end of shaft 22 and attached thereto. Thus, rotation of the shaft produces identical rotation of the attached segmented drive gear 28. As shown in FIG. 4, the drive gear 28 includes only two teeth 30 and a rim 32. It also should be noted that pinion gear 26 includes two types of teeth. One half of the pinion has eight teeth which mesh with the gear 24. The other half of the pinion includes only four teeth which are extensions of every other tooth and of the eight tooth pinion. These longer teeth members are extensions and do not function as gear teeth in the commonly accepted sense but cooperate with the rim 32 after the teeth 30 have driven the pinion to thereby allow the rim to nestle within these teeth extensions (full teeth) to act as a stop to prevent additional rotation of the pinion except when driven by the drive gear 28. As shown in FIG. 4, the segmented drive gear 28 has two teeth 30 which index with each of the eight teeth on the pinion 26. As mentioned earlier, of the eight teeth on pinion 26, four (every other tooth) extend further than the other four and extend completely across the pinion. The drive gear rotates at one revolution per hour. After the drive gear 28 meshes with teeth of the pinion gear 26 and index the pinion gear two teeth, the rim 32 then nestles within the full length teeth preventing further rotation of the pinion gear 26. This feature is important in preventing override as the clock hour cylinder rotates, is adjusted or moved suddenly. In operation, the motor 36 turns shaft 22 at one revolution per hour. This shaft rotation turns the attached, segmented drive gear 28 at the same speed. As gear 28 rotates at one revolution per hour its two teeth 30 mesh with teeth of pinion 26 to turn it one quarter of a revolution (two teeth). The hour cylinder gear 24 is rotated by pinion 26 at the speed of one revolution every twelve hours. Thus, the drive pinion gear 26 rotates two teeth every hour causing the larger gear 24 which has twenty-four teeth to be driven two teeth or one-twelfth of a revolution to turn the hour roll 19 each hour to a new hour. It is observed that the minute roll 21 rotates a constant speed to indicate five minute intervals before and after each hour. The hour roll moves abruptly and quickly at the change of each hour when teeth 30 of the drive gear 28 rotate the pinion 26 and the larger gear 24 which in turn rotates with the hour cylinder 19. The entire arrangement of components is powered by a drive motor 34 to which an adapter 36 is attached to allow the motor to be connected with the shaft 22. Also, a number of small roller bearings 38 may be utilized to mount the shaft in the various flanges 16, 18, 18a and 20 in order that it rotate smoothly and produce a minimum of drag. Thus, a very small horsepower motor can be used with a simple one and one half volt battery to power the motor. One type of motor which has been found effective is a quartz motor manufactured in Germany by Junghans and identified as model number W-757. Thus, it has been shown by the foregoing that a novel type of clock has been disclosed whereby the large minute cylinder indicates five minute segments of time after each hour and then after indexing to the next hour indicates the time before the hour in five minute segments. The cylindrical time indicators 19, 21 are balanced as is the remainder of the clock and thus only a fractional power motor is used because there are no unbalanced forces. Even the drive gear which has only two teeth of a gear segment is balanced because of the locking rim which it is provided with. Similarly, the pinion member also is balanced and provides no uneven forces to be overcome by the drive motor. The foregoing description and drawings merely explain and illustrate the invention and the invention is not limited thereto, except insofar as the appended claims are so limited, as those who are skilled in the art and have the disclosure before them will be able to make modifications and variations therein without departing from the scope of the invention. Referenced by
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Evos at Import Face-Off Tulsa.mov Tulsa Evos Invade Import Face-Off Tulsa 2011. Was a good show even with the chance of rain at 60%.
Evo8 300km in 23sec Rocket launch....23 seconds to 300kmh...
Evo AMS 750 WHP ! First Test Drive...
camaro vs evolution arrancones moroleon gana Camaro
MUST SEE!!! DG Motors EXCLUSIVE Evo X (10) 670whp Dynojet E85!!! SMOKING Check us out at our website: http://www.dgmotorsnys.com Or our facebook: http://www.facebook.com/#!/pages/D-G-Motors/104125642986062 DG Motors is Located at 666c West Hoffman Ave. Lindenhurst NY 11757 Here is phase 1.5 of tuning our re-built Lancer Evolution X Gsr for the late 2010 racing season. This build consisted of replacing our stock appearing blouch dominator 2.0 turbo (which ran a best pass of 11.4 @ 122mph) with an Extreme turbo Systems Billet T3 PT67-65 turbo Kit. We also removed the entire long block out of the car to be custom built to our specs with a full Cosworth Bottom End. We are now using Cosworth Pistons, Rods, Bearings, Rings, and Head Gasket. Gino, from Evolution Racing Engines in Amityville, Ny performed a complete Port and Polish along with an extreme valve job to match GSC's S2 274/274 Camshafts high duration and lift. Furthermore, an AMS 600HP Fuel System was customized by us in utilizing Twin External/In-Line Bosch 044 Fuel Pumps feeding a -8 Feed and Return line to an AMS Fuel Pressure Regulator Kit and AMS Fuel Rail feeding Fuel Injector Clinics 2150 c.c Injectors. We also decided to purchase an Exedy Twin HD Re-Build kit to freshen up our clutch which had numerous mid-11 second passes at EnglishTown, Race Way Park. Last but not least, The new Tial Q 50mm Blow Off Valve replaced the stock metal valve which starts leaking at the 27psi marker. We have now successfully maxed out the stock factory MAF Housing which registers 4.99 Volts from Peak Boos/Torque to our Red-Line of 10,000rpm. The stock factory MAP Sensor also caps itself out at 33.4psi. We are upgrading to an Omni 4-Bar map sensor to run upwards of 50psi in hopes to max out our Precision T3 Billet 67-65 turbo and achieve an absolute minimum of 825whp. Our conclusion for the 2010 Racing Season motivates us to become a few World Record Holders consisting of: The World's Highest HP Evo X Gsr with the Stock ECU, Stock MAF, and E-85 Fuel. Lastly, we are motivated to become The World's Fastest and Quickest Evo X Gsr, period...Extreme thanks goes out to all our sponsors, clients, friends, and fans who are making all of this possible, especially: Extreme turbo Systems, Ams Performance, Evolution Racing Engines, Cosworth, GSC, Precision turbo, Fuel Injector Clinic, Tial, Hallman, Supertech, Exedy, Ecuflash/Evoscan (Tephra, Golden). Thank You.
Wraptivo Lancer Evo X FonzoJay Tuned Wraptivo Mitsubishi Lancer Evo X Featuring Wraptivo Matte White - Body; Wraptivo Carbon Black - Hood, Roof, and Grill
Lancer Evolution 8. Top Speed 0-300 kmh Lancer Evolution 8. Top Speed 0-300 kmh
Evo X - One lonely night. A test run I did with a friend of mine Ruben E. Reyes on some cinematic video footage. Shot with a nikon d90 and a nikon d5100, edited with final cut pro x. www.tikitillmanphotos.com
SSP - One hell of a driveway !!! Over 1730 WHP in total . Evo X GSR - Evo X MR- Nissan GT-R, Custom Hyundai
Porsche 997 Turbo Vs. Mitsubishi Lancer EVO X http://www.1000hp.eu Follow Us On FaceBook: http://www.facebook.com/1000HP.EU Hungary - KiskunLacháza - KOE [2009 - 09 - 06]
Mitsubishi Evo 8 vs Porsche 911 Turbo Mitsubishi Evo 8 vs Porsche 911 turbo @ asia afrika senayan
GTR vs EVO X THIS EVO X NOW MAKES OVER 750WHP.. subscribe to our new channel to see all the upcoming videos of the build to achieve 900WHP. Do it..NOW :D New Channel- https://www.youtube.com/user/mericastreetscene?feature=results_main a 2011 evo x races a GTR from a roll and a dig.
WRX STI vs EVO X апрель 2011 Томск нефтехим
NISSAN GT-R vs MITSUBISHI EVO X Visit http://www.fastandfurious.netau.net/ We offer discount auto parts and performance accessories and have the largest on-line inventories of Performance & Replacement Auto Parts on the net with over 1 million parts.
Tesla Model S P85D vs Ferrari F12 Drag Racing 1/4 Mile
2015 Lamborghini Aventador 750-4 SV
Audi RS-7 Sedan Rips a 10.6-second 1/4 Mile @ 130 mph
2015 Corvette Z06 with Automatic Transmission runs 10.7 @ 129 MPH Drag Racing 1/4 Mile
Which car is faster?
Similar 1/4 mile timeslips to browse:
2012 Fiat 500 Abarth ATPTURBO: 13.642 @ 100.850 Coleman L., Engine: Stock, Supercharger: N/A Turbos: ATP bolt-on Garrett GT upgrade Tires: 225/50/15
2012 Fiat 500 Abarth: 15.170 @ 90.340 Charlie Lindstrom, Engine: 1.4L Multiair 4-cylinder, 0 Turbos: 1 Tires: BF Goodrich G-Force Sport Comp-2
2012 Fiat 500 Abarth: 15.610 @ 89.220 FikseGTS, Engine: 1.4L 4 turbo,
2012 Fiat 500 Sport Automatic: 19.500 @ 71.200 Barry,
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Reverse Transcriptase Inhibitors
Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
Non-Nucleoside Reverse Transcriptase Inhibitors in Development... Non-Nucleoside Reverse Transcriptase Inhibitors NNRTIs in Development NNRTIs No Longer in Development Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact...fusion inhibitors Fact Sheet 470 : new classes of antiretroviral drugs Fact Sheet 480 : immune therapies These drugs have not been approved by the Food and Drug...
Ask the Experts
Reverse transcriptase inhibitors effect on telomeresI recently started on Atripla and was trying to understand how it works and potential long term effects. So as I understand it (and I'm not a microbiologist by any stretch) the main purpose of the Sustiva in Atripla is to inhibit the reverse...Response from Keith Henry, M.D.
University of Minnesota, School of Medicine
...I am not aware of any data that has shown that nucleoside reverse transcriptase inhibitors (that are HIV DNA chain terminators not directly involving human DNA) clinically impact human chromosome or telomore length/function.
Read more »
My chances of reshaping my body with hiv?I've been positive since 1988, presently on kaletra and epzicom. What can I do to lose extra fat? Don't want to look sick but can't be overweight and uncomfortable eitherResponse from Gerald Pierone, M.D.
AIDS Research and Treatment Center of the Treasure Coast
...that have shown improvement in lipohypertrophy when protease inhibitors (Kaletra in your case) are switched for non-nucleoside reverse transcriptase inhibitors (NNRTIs). If you have been on treatment with this class in the past and have virus...
Read more »
Are Ritonvir / Combivir twins?Read about life threatening danger of Ritonvir + E. What about Combivir + E? Combivir is not the same as Ritonvir is it?Response from Keith Henry, M.D.
University of Minnesota, School of Medicine
...Combivir (combination of 2 nucleoside reverse transcriptase inhibitors) is zidovudine (AZT) + lamivudine (3TC) which is different than ritonavir (Norvir) which is a protease inhibitor. KH
Read more »
ARV'swhat are the ARV'S made up of and how do you classify them?Response from Eric Daar, M.D.
UCLA School of Medicine
...Currently available antiretroviral (ARV) medications are classified as being nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs) and fusion...
Read more »
Nucleoside Analog Reverse Transcriptase Inhibitors in Development... Nucleoside Analog Reverse Transcriptase Inhibitors Nucleoside Analogs (Nukes) in Development Nukes No Longer in Development NOTE: Several fact sheets describe drugs that... are being tested against HIV: Fact Sheet 430 :... Read more »Pharmacokinetics of MKC-422, One of the Next Non-nucleoside Reverse Transcriptase Inhibitors, Together with ZDV, 3TC, d4T, and ddI...is metabolized by the cytochrome P450 liver enzyme CYP3A4, the enzyme responsible for metabolizing the other non-nucleoside reverse transcriptase inhibitors as well as the protease inhibitors. Other NNRTIs and protease inhibitors have not been... Read more »United Kingdom: "Virological and Immunological Outcomes at 3 Years After Starting Antiretroviral Therapy with Regimens Containing Non-Nucleoside Reverse Transcriptase Inhibitor, Protease Inhibitor, or Both in INITIO: Open-Label Randomized Trial"...-- a large international randomized trial -- the study authors compared antiretroviral therapy with two nucleoside analogue reverse transcriptase inhibitors (didanosine + stavudine) plus either a non-nucleoside reverse transcriptase inhibitor... Read more »Clinical Trials of HIV-1 Reverse Transcriptase Inhibitors (Session 40) Clinical Trials of HIV-1 Protease Inhibitors (Session 41) Immune Reconstitution (Session 45) Treatment of Primary Infection (Session 47)... Clinical Trials of HIV-1 Reverse Transcriptase Inhibitors (Session 40) START Observational Study: Longitudinal Follow-Up of Virologic and Immunologic Responses in START I and START Read more »
Connect With Others
Lab, med change, confusion
Posted by kaplan08, 2 Replies
Labs of last year have shown a vload range between <400 and 793, with <400 being most recent; CD4 percentage range from 31% to 34%, with 33% being most recent. Taking only Viramune and Combivir -a test has recently shown resistance to...
Read more »
DDC Bites the Dust
Posted by Bear60, 1 Reply
...Pharmaceuticals announced that it will be ending the sale and distribution of Hivid (zalcitabine, also known as ddC), a nucleoside reverse transcriptase inhibitor (NRTI) originally approved in 1992. The tablets will not be available in U.S....
Read more »
Should i Start medication???
Posted by coconyc, 3 Replies
Hi im Coco from nyc I though the benefit or getting tested its to find out the virus in a early time so u can get a good treatment that prolong ur life in a better condition, i got my first results a month ago and i got CD4:276 and VL: 3616, so my...
Read more »
Prezista - New PI designed for Resistant Virus
Posted by Survivor, 2 Replies
...in J&J's HIV franchise, which aims to combat HIV drug resistance Prezista will be followed by TMC125, a non-nucleoside reverse transcriptase inhibitor typically used in combination with other drugs expected to be launched in late 2008. That...
Read more »
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Top Posts
Bonzie Colson continues hot streak as No. 12 Notre Dame wins at No. 16 Louisville
Mar 4, 2015, 9:38 PM EST
Colson and Demetrius Jackson scored 11 second-half points apiece in Notre Dame's win at Louisville.
Defense turns into instant offense for Ohio State's Sam Thompson (VIDEO)
Mar 4, 2015, 9:03 PM EST
D'Angelo Russell scored 28 to lead the Buckeyes, but none of his points were wilder than the two scored by Thompson on this play.
Frank Kaminsky, Jahlil Okafor among ten semifinalists for Naismith Award
Mar 4, 2015, 5:13 PM EST
Kaminsky is one of five seniors on the list, and Gonzaga is the only program with two representatives.
Pregame Shootaround: Notre Dame-Louisville highlights a huge night on the bubble
Mar 4, 2015, 2:25 PM EST
There are a lot of big bubbles games tonight.
Bill Self says Perry Ellis sprained knee, back in 'a week or so'
Mar 4, 2015, 10:42 AM EST
Perry Ellis suffered a nasty looking knee injury last night.
Dez Wells had the craziest defensive play of the year last night (VIDEO)
Mar 4, 2015, 10:15 AM EST
I've never seen this happen before.
Virginia's Justin Anderson could return as early as Saturday
Mar 4, 2015, 9:41 AM EST
Justin Anderson has been out for more than three weeks after fracturing a finger.
Missouri Valley Conference Tournament Preview and Postseason Awards
Mar 4, 2015, 9:00 AM EST
Two strong teams enter the Valley Conference Tournament with numerous others trying to enter the frame.
No. 9 Kansas rallies to beat No. 20 West Virginia in OT but injury to Perry Ellis is major concern
Mar 3, 2015, 11:58 PM EST
No. 9 Kansas topped No. 20 West Virginia but now the Jayhawks must worry about the health of Perry Ellis.
Late Night Snacks: Kansas wins in OT; Kentucky survives; Georgetown, Iowa earn quality road wins
Mar 3, 2015, 9:59 PM EST
Georgetown and Iowa earn big road wins.
Cincinnati guard granted release; will likely be a graduate transfer
Mar 3, 2015, 7:00 PM EST
Cincinnati could be losing an experienced guard for next season.


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Download mockAP iPhone iPad iOS
iOS mockAP 1.0 Mobile
Customer Reviews ?I though we would be able to design a app, but it seems that you can`t. All you can do is, is really nothing. But I could be wrong. Please update, or don`t get it. More in Productivity - for mockAP iPhone
More by Michael Ried - for mockAP app ioS


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Roto-Steam cleaning and powerwashing for hood and exhaust systems!
5936 Pillsbury Ave S
10 locations serving 27 states
MON 24 Hours | TUE 24 Hours | WED 24 Hours | THURS 24 Hours | FRI 24 Hours | SAT 24 Hours | SUN 24 Hours |
Open 24 Hours / 7 Days a Week
Enviromatic Corp of America is a Restaurant Hood & Duct cleaning system, offering the expert Roto-Steam cleaning and powerwashing to commercial and industrial customers in Minneapolis-St. Paul and throughout Minnesota. We are specialists in the kitchen grease exhaust field.
Whether you are looking for one-time service, regular maintenance or expert clean-up because of fire damage, Enviromatic Corp of America responds promptly to provide quality service.
We are fully licensed, bonded and insured steam cleaning company offering free estimates and 24-hour service. Our capabilities include:
• Hood and exhaust system cleaning
• Blower and fan balancing and repair
• Vibration analysis
• Rooftop grease and oil collection and containment systems
• Spinjets, floorcleaners and car wash parts
• Grease filters from several manufacturers
• Access plates for grease ducts
• Grease absorption replacement pads
• Restaurant hood cleaning
• Restaurant duct cleaning
• Restaurant hood & duct cleaning
• Restaurant fan repair
• Restaurant vent repair
• Restaurant vent cleaning
• Roof grease cleaning
• Rooftop grease cleaning
• Restaurant Roof grease cleaning
• Restaurant blower repair
• Restaurant blower cleaning
• Hood & duct
• Restaurant blower
• Kason grease filter
• Mosmatic duct cleaner
Enviromatic is based in Minneapolis, MN and we offer our services in the 27-state surrounding areas with satellite shops located in the Midwest, Southeast, and South Central U/S.
For Roto-Steam cleaning by experienced technicians, depend on Enviromatic Corp of America. We do not use subcontractor for our cleaning service!
Call today for a free estimate!
Category: Cleaning Services|Restaurant Equipment and Supplies
DexKnows Mobile profile for Enviromatic Corp Of America in Minneapolis, MN


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5 Its not sh*t he's shooting!Rippler | 28/09/2009 | See all Rippler's reviews (1)This book is everything I love about Kevin Smith. His ability to turn what would normally be boring conversations into something that you want to hear is brilliant, and this book shows that in full.There is a good chance if you have seen his Q&A dvds you will be aware of some of the stories, and of course if you listen to SModcast you will certainly know them, but it does not stop these stories being great. Highly recommended, especially at £5.99!!
4 A week earlyLazyMoFoNo1 | 25/09/2009 | See all LazyMoFoNo1's reviews (3)i just recieved my copy only read first few pages but it translates to book really well. The reason i only gave it 4/5 is cos the finish of the book ain't the greatest but not too bad and my copy has been badly beaten up in the mail, i can't complain though i recieved it a week before it was supposed to be released


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(based on 76 reviews)
Ratings Distribution
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
of respondents would recommend this to a friend.
Best Uses
Reviewed by 76 customers
Sort by
Displaying reviews 1-10
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These pill boxes work very well.
By Gooche
from NC
About Me Budget Buyer
Comments about 14 Day Pill Holder:
The plastic was split when it came, but I was able to mend it successfully, using clear, heavy duty packing tape.Otherwise, this is a very good product.
Good value
By Poohbie
from Pittsburgh
The tapestry cover is very nice. This item is great for vacations or spur of the moment trip extensions. While the slots aren't very large it is still good as there are time of day slots I do not use. I liked mine so much I bought one in black for a travel companion.
I always use this holder daily.
By bobbie
from honolulu, HI
the compartments are little too small for capsules and gel pills.
Great Product!
By Judy65
from Castle Rock, Washington
About Me Brand Buyer
This pill organizer is really great!
Purchased 1 of each - not the same size!
By Disappointed
from Omaha, NE
Bought one of each (black & tapestry) so my husband & I could easily tell them apart; however, the tapestry one is quite a bit smaller than the black, yet the description indicates they are the same size. Larger pills will not fit in the compartments. Disappointing!
(1 of 1 customers found this review helpful)
The Best I have found.
By Tee
from Camden, South Carolina
This was bought to keep daily meds in. I really love the 2 week format and the 4 compartments per day. I find them durable, easy to use at home or for travel and a great size. This is well made and I like the little case to protect them.
Good looking cover
By Kathy
from Cleveland, Ohio
I like the item because I keep it in my computer room and it does not look like a pill container and it holds two weeks worth of pills.
Makes a nice gift
By carrollcats
from Springfield, MO
This will make a great gift for my Dad as he takes pills different times of the day.
Compact and pretty
By mamaharv
from Marion Ny
I really like this.I can do all my meds for two weeks.It is easy to carry in my purse and it is so pretty.
Awesome purchase
By Weezy32
from Kentucky
Keep by my chair so we do not forget to take our medicine.


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Click here to print the obituary below
Marian Patnaude(1929 - 2014)
MIDDLETOWN - Marian (Bednar) Patnaude, 84, was so gently called to heaven on Monday, March 24, 2014.
Marian was born to Michael and Suzanne (Gayara) Bednar on Feb. 23, 1929, in Hebron. She moved to Middletown and graduated from Middletown High School in 1947. Marian began working at Sears and Robuck where she met the love of her life, "Franny" Patnaude where they both were employed. Fran and Marian were married 61 years until Fran passed in 2012. Together they raised three wonderful children who went on to marry very special people and gave Fran and Marian five beautiful grandchildren. Fran and Cathy (Russell) Patnaude, of Bethlehem, both artist and teachers. Fran is Department Head of Rumsey Hall School and an adjunct professor at Western Connecticut State University while Cathy teaches in Regional District 14, parents of Nick, who currently is teaching in Istanbul, Turkey, Nathan who resides in Pittsburgh, Pa., and Emily, of Litchfield and teaches in Oxford. Steve and Betsy (Neumann,) of Columbia, S.C., where Steve teaches High School English and is a musician and Betsy a Video Artist and Program Director for The Columbia Public Broadcast Station. Also, Kathy and Greg Hancock, of Old Lyme, where Kathy teaches fourth grade and are owners of Hancock Pharmacy of Meriden and Long Wharf in New Haven, parents of Dr. Melyssa Hancock who is fulfilling her Otolaryngology Residency at Georgetown University Hospital and Matt, who is completing his masters in criminal justice at The University of New Haven this summer and pursuing a career in law enforcement. Marian loved her children and grandchildren and was so proud of all of their achievements and the people they have become. She is also survived by her sister, Carol Jarzabek, of Canton; and sister-in-law, Mary Bednar, of Hillside, N.J.; along with many nieces, nephews; and special friends. She was predeceased by her husband, Francis T. Patnaude; her sisters, Anne Masselli, Millie Kowalski, Ellen Lasky, Betty Mastzal; and her brother, Charles Bednar. Early in her life, Marian worked at Sears Robuck and Topps Department Store as bookkeeper. She then banquet waitressed and ultimately worked for Farmers and Mechanics Bank where she retired after 15 years. Marian lived a rich and full life devoted to her faith and her church, St. Pauls Lutheran Church where she was a member of the choir and volunteered as treasurer for many years. Marian was very active in the church and helped on various committees. Marian was also an active member of the
Elks Lodge
Emblem Club. She was often an officer in the club and spent many hours organizing events and working at fundraisers. Once Marian retired, she was able to travel and became an active member of the Middletown Middletuners Choir where she continued her love of singing. As Marian was a social soul, she also attended Middletown Adult Day Care to continue to be around friends. In 2013, Marian left her Middletown home for the "resort" as she called it, Gladeview Rehabilitation and Health Care Center in Old Saybrook where from day one, she received personal care and attention on a daily basis. Anyone who knew Marian found a friend, she was friendly, compassionate and always willing to lend a hand. She was very social, loved to have fun and could be found often hanging out with her sisters. Marian stayed connected to her family by always visiting them and taking an active interest in their lives. She was dearly loved by so many and will be truly missed.
Marian's family wishes to thank caregivers Alicia and Sandra who helped Marian while at home, all of the staff at Gladeview who made Marian's last few months so meaningful for her and took the time to make her smile and Masonicare Home Health and Hospice, Eastern Hospice Team where in lieu of flowers donations can be made: c/o The Masonic Charity Foundation Of CT, 74 Cheshire Road, PO Box 70, Wallingford, CT 06492.
Funeral services will be held Monday, March 31, at 9:15 a.m. from the Biega Funeral Home, 3 Silver St., Middletown followed by an 10 a.m. Funeral Mass at Faith Lutheran Church. Burial will be in Calvary Cemetery. Friends may call at the Biega Funeral Home Sunday, March 30, from 4 to 6 p.m. To share memories or express condolences online please visit
Funeral Home
Beiga Funeral Home
3 Silver Street
Middletown, CT 06457
(860) 346-1055
Published in The Record-Journal on Mar. 27, 2014


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Three brothers at work
Believed to be the three Fenner brothers who worked together at Northridge Furniture Co. in the 1920s and thirties. Ed and Harry delivered furniture by horse and cart, then later by truck. This is why ... show more
- Album: All photos
- Heart Unheart
- Comment


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The Little Nell has partnered with Maclaren to offer our guests complimentary strollers while they are in Aspen. It's one less thing to have to pack when getting the kids ready for a trip! Maclaren has been making baby strollers for more than four decades. The strollers have accessories that go above and beyond your… Read more
TAGS: luxury hotel
Holiday Parties!
We know, it's not even Halloween yet, so we're even a little hesitant to talk about it… but the holidays are coming! While it's too early to start decorating, it isn't too early to start planning. "You should book holidays parties early for the best deals and dates," said Shawna Rahm, events manager at The… Read more
Welcome to The Nell
Take a two minute look at The Little Nell and what it has to offer in all of Aspen's glorious seasons. [vimeo http://www.vimeo.com/47041662 w=500&h=281] For a complete listing of fall and winter specials, visit The Little Nell.


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Customers Also Bought
Product Description
- Size: 27 x 32 x 10cm/10.6 x 12.6 x 3.9in(W x H x T)
- Material: Canvas
- With flap design, it is convenient to get items inside the canvas bag
- Zipper closure of the canvas pack can keep items safely
- The material of the canvas purse is easy to wash
- The strap of the messenger bag is adjustable
- This messenger bag is a simple and effective way to carry your outdoor small items
- Phone pocket, card pocket and zipper pocket are inside
How to Measure:
- With unique design, the style of the cool man messenger bag is brief and classic, which shows your outstanding temperament
- This canvas bag can hold a lot of things, such as phone, glasses, purse, lighter and so on
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- Made of high quality material, this messenger bag is durable enough for your daily use
- The perfect fit for contemporary lifestyles makes it the most practical men messenger bag for everyday life
- This messenger bag with special design is easy to match with your outfit
How to Wash a Canvas Bag:
More people are thinking green and taking their own fabric bags when they go shopping. Canvas is a prime fabric for bags because it is sturdy enough to hold some weight, and a canvas bag can last and be reused for a long time. Keeping canvas bags clean is not difficult
- Remove all structural pieces from the bag, such as a vinyl-covered, flat piece of cardboard that fits into the bottom of some bags
- Pretreat any stains on the bag with laundry stain removers. Follow the manufacturer's directions for best results. One such product is Fels Naptha soap. To use, wet one edge of the bar of soap and rub on the stain or spot
- Wash plain canvas bags in the washing machine only if they have no decorative items sewn on or other features that would be damaged by machine washing
- Scrub the bag by hand if machine washing would likely damage the bag. Use a soft scrub brush or an old terry cloth. Dip the brush or cloth in laundry detergent mixed with warm water, shake off or wring out excess water and, using a circular motion, wash the entire area of the bag that is washable
- Rinse the bag carefully, taking care not to get nonwashable areas wet
- Allow the bag to air dry. If washed in the machine, dry in a dryer or on a clothesline
Package Included:
- 1 x Men Messenger Bag
• If the order has not been shipped; please contact DinoDirect Live Support for order cancellation.You will get your refund within 24 hours.
• If the order has already been shipped; you may return the item to us postmarked within 30 calendar days of delivery. Please contact our Live Support to inform that.
• Please contact Live Chat or click here to learn more return policy.
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'Mara Clara' stars visit 'Us Girls'
-A A +AThursday, August 18, 2011
MANILA -- "Way Back Home" stars Julia Montes and Kathryn Bernardo share their fashion and fitness secrets Thursday night on "Us Girls".
Julia and Kathryn, with their leading men Sam Concepcion and Enrique Gil, will unveil their simple but easy activities to remain healthy and beautiful inside and out.
Meanwhile, the fab trio Iya Villania, Chesca Garcia-Kramer, and Angel Aquino will hunt for hangout spots and inexpensive dining places with good food and great value in the metro.
Radio's popular DJs like Jasmin of Tambayan 101.9 and Papa Jack, on the other hand, will offer their warm advice for our Kabarkadas' romance and relationship problems.
Watch "Us Girls" Thursday at 9:30 p.m. on Studio 23. (Glaiza Jarloc/Sunnex)
Forum rules: Do not use obscenity. Some words have been banned. Stick to the topic. Do not veer away from the discussion. Be coherent and respectful. Do not shout or use CAPITAL LETTERS!