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Home � NH Angle
Gun shop owners: 'No... I don't have any damn .22 ammo'
The shortage caused a customer of Village Gun Shop, in Whitefield, to provide owners Stan and Sandy Holz with T-shirts that say: "No... I don't have any damn .22 ammo."
Lecture will feature 2 retired U.S. Supreme Court justices on same New Hampshire stage
Fitzwilliam man finally able to remove previously mined stone from his property
Mazzaglia has until Monday to file appeal
New Hampshire Supreme Court upholds Nazi sympathizer�s enhanced punishment
Neighbor's alleged cemetery trespass case heads to trial in Laconia
Hampton woman hurt in crash sues Portsmouth teen driver
Concord robber�s high court appeal sparks debate on police personnel files
NH Supreme Court orders resentencing of kidnapper
Concord Monitor: A legal shift for state�s taxpayers
Role Call: How �establishment� Republicans got the House candidates they wanted
Concord Monitor calls on feds to raise gas tax, unearned income tax credits
Boston Magazine: It was a weird week in New Hampshire politics
Slate - Eric Holthaus: Don't waste your money on a Farmer's Almanac
NYT - Frank Bruni: American Horror Story
Boston Herald - Kimberly Atkins: Political fallout only reason Obama waiting on amnesty
Concord Monitor decries gender pay gap in professional tennis
General News
Cops: Salem man arrested in Mass. for streaming video from women's restroom to device
Arlington police are investigating whether a Salem, N.H., man accused of using a planted camera to watch unsuspecting women use the bathroom at a local cafe may have videotaped female patrons at other area restaurants.
Phillips Exeter alum pleads guilty in killing of her alleged rapist
Born in Mexico, Esparza came to Santa Ana as a child and her life was forever changed when she obtained a scholarship to attend the elite Phillips Exeter Academy in New Hampshire.
Plaistow police lieutenant investigated for traffic stop irregularities
PLAISTOW � The New Hampshire Attorney General's Office and Rockingham County attorney's office are investigating longtime police Lt. William Baldwin for 'irregularities' that occurred during two recent traffic stops, Town Manager Sean Fitzgerald said.
Keene Cop Block returns with updated flyer
Rule 1 - Record your interaction; Rule 2 - 'Am I being detained?'; Rule 3 - Never answer questions; Rule 4 - Never consent to searches; Rule 5 - Be polite, but firm.
Eisenhower's Rolex on display in Manchester, expected to fetch $1M at auction
It was on display at Bellman's Jewelers in Manchester. It may be the first and last time it will be on public display before it's auctioned off this coming week.
Former captain of submarine destroyed at Portsmouth Naval Shipyard relieved of command
The reason cited is 'a loss of confidence in his ability to serve effectively as commanding officer.'
NH Fish and Game arrests ATV riders after getting stuck in wetlands
A Hudson man was arrested Friday evening in the North Country after he was found operating an off-highway recreational vehicle in a wetland, according to New Hampshire Fish and Game Conservation Officer Christopher Egan.
From TV to the big screen, 'The Leftovers' star Ann Dowd is everywhere
At some point midsummer, Twitter became an Ann Dowd fan club.
After 5-year suspension for sex with patient, Gilford psychiatrist may reapply for medical license
Bahder voluntarily surrendered his license in February 2009 after he engaged in sexual activity with a female patient following her treatment for cocaine dependency while she was incarcerated at the Belknap County House of Correction.
Manchester man dies in accident early Friday in Moira, NY
The vehicle hit a guide rail, became airborne over the river and struck several large rocks before coming to rest on the east bank.
Spectacular images of Northern Lights from perchatop Mount Washington
The Northern Lights Shined on New England in Incredible Color Last Night
Two arrested for operating alleged meth lab in Berlin
The N.H. Attorney General's Drug Task Force said Linda Greenlay, 43, and Anthony Elwell, 40, have each been charged with one count of possession of methamphetamine and one count of manufacture of methamphetamine.
Getting advanced prosthetics to those who need them
The DEKA Arm System, about the same size and weight of an adult�s arm, can pick up an egg from a carton or a credit card from a desk.
Should violent students be required to wear electric shock devices? Some of parents say yes as FDA considers ban
Andrew Goldberg spent years at a New Hampshire facility, where his mother says he bit, hit and kicked staff members. When restraints did not work, workers tried medications to calm him.
Competitive pricing, liquor contracts target revenue lost to New Hampshire, but is Maine doing enough?
LEWISTON � A state effort to recapture revenue Maine loses in alcohol sales to New Hampshire by lowering prices is underway, but some state officials and others worry the effort isn't being implemented as aggressively as first intended. And that Maine may never get the revenue first projected.
Man found unconscious at Winchester Speedpark Saturday
Winchester Sgt. Mike Tollett said he didn�t know if the man had crashed a motorcycle, and didn�t know the extent of his injuries. There was a race listed today on the park�s website. No one from the park was available for comment Saturday night.
Why sapphire screens in the iPhone 6 were a pipedream
Hindsight is always 20/20 when it comes to new products, especially those as influential as Apple's (NASDAQ: AAPL ) .
Lebanon man killed in Lexington, Mass. crash that snarled Route 128 traffic
Police identified the driver in the Saturday accident as 40-year-old Charles Vancor of Lebanon, New Hampshire.
Dartmouth College theme housing includes Harry Potter
HANOVER, N.H. (AP) � From Harry Potter to the 'Herbifloor,' campus housing is becoming increasingly specialized at Dartmouth College.
Nova Star will look to rebound from rocky start
About 100,000 passenger trips were anticipated, but slightly more than 45,000 were booked.
Most Read
Keene Cop Block returns with updated flyer
Most Comments
NH couple hit slot for $2.4m in Las Vegas
Most Shared
Keene Cop Block returns with updated flyer
Video shows apparent beheading of British aid worker
Clintons returning to Iowa amid 2016 speculation
Lecture will feature 2 retired U.S. Supreme Court justices on same New Hampshire stage
Nova Star will look to rebound from rocky start


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Welcome to West Virginiaand the very finest in West Virginia lodging hospitality.
This website is dedicated to those travelers seeking relaxing and memorable West Virginia lodging. Our member innkeepers are truly proud of West Virginia and go out of their way to welcome visitors, to share a bit of themselves and to guarantee they will make every effort to make your Bed and Breakfast stay a memorable one.
Whether you are a first time Bed and Breakfast guest seeking an alternative to a West Virginia hotel or a seasoned B&B guest who wants to find new favorites, our site provides access to the finest in West Virginia lodging choices throughout the state. You will find B&B's ranging from small quaint log cabins and restored farmhouses, to classic mansions and historic inns. Each West Virginia Bed and Breakfast Association member warmly welcomes you to relax, rejuvenate, and enjoy our distinctive quality accommodations.
WVBBA member inns have been unaffected by the water problems affecting the area around Charleston, WV, and we continue to provide a safe lodging experience for our guests. Please double check with the owners/innkeepers at any of our member properties if you have questions, but we hope you will continue to enjoy the authentic hospitality that West Virginia B&Bs are eager to provide for you!
Just click on the map to view a larger map with the areas of the state you wish to explore, and experience mountainstate hospitality with us. Visit a WVBBA Bed and Breakfast and enjoy the West Virginia Better Way to Stay!
Order our WVBBA cookbook Inn our West Virginia Kitchens by clicking here.
The West Virginia Bed and Breakfast Association is your passport to Civil War history throughout the Mountain State. Born of the Civil War, West Virginia offers countless opportunities to explore the history of that turbulent time, even while enjoying the traditions and serenity of its historic towns, mountains and rivers

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We are based on the South Island with rugged snow capped Southern Alps as your back drop.
Packages can be personalised to suit your needs.
Depending on the New Zealand package you choose accommodation will vary from tent to hunting lodge.
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|Mar 15 - April 30
|Buddy hunt, free range, private land hut accommoda
New Zealand Hunting Guides
Kaikoura, New Zealand Hunting Guides
Experienced, professional hunting guides offering Red Stag, Tahr, Chamois, Elk, Boar and Ram hunts. Estate & free range hunts amongst New Zealand's magnificent mountains near Kaikoura plus luxury hunting lodge accommodation. Family owned and operat...
Hunting & Fishing Tours of New Zealand
Canterbury, New Zealand Hunting Guides
Backcountry New Zealand, Tours that are designed to exceed your expectations and maximise your New Zealand experience. We are one of New Zealand's leading hunting and fishing outfitting services, with over 25 years of experience....
$400 Per Trip
Beachfront Hunting Fishing Loghouse
Gisborne, New Zealand Hunting Guides
Ultimate combo of beachfront luxury accommodation with hunting, fishing, diving, surfing, walks, horseriding and gourmet or barbecue meals staying in huge secluded loghouse lodge overlooking 5.6kms of beautiful unspoilt beach all 41kms from gisborne...
200 Per Night
Go With the Flow Drift boat fly fishing!
Canterbury, New Zealand Fishing Trips
Drift boat guided fly fishing trips, West Coast or Canterbury. Experienced river guides, accommodation, meals, equipment and transport....
Sportsfishing Charter Boat New Zealand
Northland, New Zealand Fishing Trips
You will be cruising on a luxury sportfishing vessel with a highly experienced crew who will cater for your every need. The MV Independence is a 45ft Caribbean Bertram powered by twin 6V92 Detroits delivering 1100 hp. The vessel cruises at 18 knots. ...
Starting at $2,000 Per Night
Father Son/Daughter - Back Country Experience
North Island, New Zealand Fishing Trips
Treat your son or daughter to the real New Zealand back country experience, with your own personal guide. Design your own experience fishing, hiking, hunting, riding & more at Poronui Safari Camp on the River....
Specials from $1,680 Per Trip
Kingfisher Fly Fishing Guides & Lodge
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Fly fishing guide Ben Kemp provides all-inclusive full service fly fishing packages for wild brown trout, Lake� Brunner region, New Zealand - "Where the Brown Trout Die of Old Age!"...
$360 - 475
NZ Snow Tours
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Based in the stunning alpine town of Wanaka, NZ Snow Tours are the original creators of personalised snow holidays in the South Island of New Zealand. This year will be our 11th year running the best snow tours in the Southern Alps!...
Starting at 1,895 Per Week
Haka Tours - New Zealand Adventure & Snow Tours
Auckland, New Zealand Skiing & Snowboarding
HAKA Tours represents the ultimate in extreme New Zealand tours. From small group adventures to New Zealand snow tours exploring the impressive Southern Alps and the active volcanoes of the North, we are here to offer you a hugely amplified NZ tour!...
$40 Per Night
Private Ski Instruction at Coronet Peak Queenstown
Queenstown, New Zealand Skiing & Snowboarding
Welcome to Adventure Villars, we are offering private ski instruction at Coronet Peak and The Remarkables. Enjoy a stress free holiday in the company of one of our qualified and highly experienced instructors....
Starting at 110 Per Hour
Romantic Bed and Breakfast in a Spectacular Spot
Canterbury, New Zealand Bed & Breakfasts
Perched above the Kaikoura township overlooking the Mountains and Pacific ocean. Austin Heights quality self-contained accommodation is only a five minute drive from the town center and all local attractions and marine life ativities!...
Starting at 249 Per Night
Albergo Hanmer Lodge & Alpine Villas
Canterbury, New Zealand Bed & Breakfasts
A Place where magic happens! Dramatic alpine views, stylish suites n'spas, S/C villas: cinema/DVD & jacuzzi. Flexitime renowned 3 course designer breakfast incl.-perfect fusion of NZ & Swiss cuisine: homely bread, fine Italian coffee. Blitz yoursel...
Starting at 240 Per Night/Room
Glentanner Park Centre Mount Cook New Zealand
Canterbury, New Zealand Campgrounds & RV Parks
Leading flightseeing and activity centre, budget accommodation provider and the only fully equipped campground with tent sites and powered sites in the Mt Cook region. Just 18km from Mt Cook National Park....
Starting at 18 Per Night
Hurunui Horse Treks
Canterbury, New Zealand Horseback Riding
Hurunui Horse Treks has been operating a variety of multi day trail rides and pack trips through the spectacular high country of New Zealands South Island since 1987....
Get high on some alpine hikes in New Zealand
Canterbury, New Zealand Hiking & Trekking
Climb high on these 2 or 3-day alpine treks. The Ball Pass Treks, and Aoraki Mt Cook Trek give spectacular views of New Zealand's highest mountains. The Tekapo Trek gives you panoramas over Lake Tekapo, the Mackenzie Basin and the Southern Alps....
Starting at 590 Per Person
Bicycle Touring New Zealand
Canterbury, New Zealand Bike Tours
Join us in New Zealand for your dream cycling holiday in one of the worlds most stunning locations. We have two five day packages that can be combined to make 11 fantastic days of riding in the South Island. Come join us soon! ...
$968 Per Trip
Kiwi Dundee Adventures Ltd. New Zealand
Coromandel, New Zealand Eco Tours
Doug & Jan are two fun loving genuine 'Kiwi' Guides.Doug Johansen is regarded as one of NZ's foremost guides with a wealth of knowledge on the natural world. His feats earned him the 'Kiwi Dundee' title in 1988, the Queens medal for services to Natur...
Starting at $230 Per Person
Queen Charlotte Wilderness Park
Marlborough, New Zealand Eco Tours
Private native wildlife sanctuary and island in the beautiful Marlborough Sounds. Miles of private walking tracks, beaches, gold mines, scuba, snorkelling, fishing, wilderness, nature....
$100 Per Night
Bush & Beyond guided conservation walks
Kahurangi Park, New Zealand Wildlife & Safari Tours
The original operator in Kahurangi National Park. New Zealand's most diverse wilderness park. Largest variety of plant species, rare birds and scenery from alpine to coastal. Trips 1 to 8 days, all ages and fitness levels....
$105 Per Trip
Queenstown Wine Trail - wine tours New Zealand
Queenstown, New Zealand Wine Tasting
First time tasters or wine connoisseurs join us for a full afternoon of wine tasting, just a short journey from Queenstown this relaxed personalised tour takes in a selection of our finest boutique wineries. Operating daily deparures at 12.30pm....
Starting at 129 Per Person
|Link Code


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Get Movie Facebook Covers for your Facebook timeline. Make your own Movie Facebook Cover & upload Movie covers to your Facebook profile and share with friends.
You'll only find the best Movie Facebook Covers on CoverUpload.com. Every cover uploaded by us is designed by us, so you won't find our unique Facebook covers on Facebook, or any other website. Our Movie covers for Facebook can also be uploaded to your Facebook page.


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With four luxurious Hotels and two cruise ships, the Sonesta allows one to experience Egypt with a style and charm that blends seamlessly with the native surroundings . It is a modern ten-story hotel surrounded by tropical landscaping .
|Check-in Policy
|Check-out Policy
|# Of Rooms
|# Of Floors
Swiss Inn Hotel Cairo
Cairo, Egypt Hotels & Resorts
The 3-Star Swiss Hotel provides high quality accommodation in Cairo for great budget prices. Relax... let us take care of you. We offer a range of excellent standard rooms...
Rates from $50 Per Night
Egypt Top Light Travel
Cairo, Egypt Hotels & Resorts
Egypt Top Light has the ability to arrange special tours and special events, all of that has formed our considerable reputation of providing excellent service and excellent facilities in order to make your holiday memorable . ...
Bed and breakfast
Cairo, Egypt Hotels & Resorts
Our hotel is called new palace ,we are located in Cairo,Egypt the hotel has 32 rooms ,25 of them are with private bath,Ac, satellite tv,wireless and roof top and we are located in the center of the City between railway station and egyptian museum...
$9 Per Night
Kempinski Nile Hotel
Cairo, Egypt Hotels & Resorts
Opened in June 2010, the Kempinski Nile hotel occupies a prestigious location overlooking the Nile in the upmarket Garden City district. The hotel has ...
$176 Per Night
Tiba Pyramids
Cairo, Egypt Hotels & Resorts
Situated within sight of Giza's Great Pyramids, the Tiba Pyramids Hotel Cairo offers guests a convenient location. The Sphinx is also located within easy ...
$65 Per Night
Hilton Zamalek Residence Cairo
Cairo, Egypt Hotels & Resorts
The Hilton Zamalek Residence Cairo is located 11 miles from the Cairo International Airport. ...
$111 Per Night
Grand Hyatt Cairo
Cairo, Egypt Hotels & Resorts
The Grand Nile Tower is a luxurious property, located directly on the River Nile, in the commercial and business area, and close to the center of modern ...
$238 Per Night
Barcelo Cairo Pyramids
Cairo, Egypt Hotels & Resorts
The Barcelo Cairo Pyramids is easily accessible from the Cairo International Airport. Situated on the plateau of Giza and recognized as a World Heritage ...
$94 Per Night
Swiss Inn Pyramids Golf Resort
Cairo, Egypt Hotels & Resorts
New charming resort hotel set right on the 27 hole Golf Course near the Pyramids ideal for businessmen golfers and families ...
$68 Per Night
Ramada Plaza Naama Bay Sharm El Sheikh
Cairo, Egypt Hotels & Resorts
The Ramada Plaza Naama Bay Sharm El Sheikh hotel is just 15 minutes from Sharm El Sheikh International Airport. ...
Dive Dahab Red Sea with Red Sea Pro
Dahab, Egypt Scuba & Snorkeling
ourselves on being passionate, professional, and personalized in all our Red Sea scuba diving trips. Dahab, Sinai, Egypt,dahab red sea,...
Starting at 5 Per Night
Dahab Diving
Dahab, Egypt Scuba & Snorkeling
Welcome Welcome to dahab Divers, a long established group of dive centres that were the first PADI dive center We aim to provide excellent service to you and to make sure your trip is as relaxing, fun packed, and as great value for money as you woul...
$30 Per Event
Egypt Nile Boats
Aswan, Egypt Sailing & Yacht Charters
Escape to the pleasures of relaxing under the sun, Visit the Temples of the Pharaohs, good food and magnificent scenery. The daily experience of sailing to a new adventure on the Nile waters and enjoying the blue sky and green Valley is rewarding and...
$3,750 Per Week
World Stamp fair travel for you and the locals
Nuweiba, Egypt Eco Tours
Every step we travel is a stamp, Which stamp do you want to leave behind?...
Starting at 65 Per Person
Essential Egypt
Cairo, Egypt Art History
Cairo including,Giza,Pyramids of Cheops & Chephren & Mycrenos,Sphinx,Sakkara,Step Pyramid of Zoser,Egyptian museum,Citadel of Saladin,Mosque of Mohamed Ali,The Hanging Church,Khan el Khalili Bazaar ,Aswan,High Dam,Philae Temple,Unfinished Obelisk,,...
$29 Per Night/Pers
Egypt travel and tours
Cairo, Egypt Cultural Experience
9 day 8 nights Nile cruise 4 nights and Alexandria and Cairo,pyramids 5 star hotel and 5 star deluxe cruise, domestic flight, guide, private transportation,meals all transfers, luxor, Aswan, komobo, Edfu,belly dance show,all travel services...
$920 Per Person
Egypt tours and packages
Cairo, Egypt History
Travel to Egypt and let Egyptra travel service manage your visit . offering both historical and recreation journeys packages , Nile cruise,shore excursions and different categories of hotel accommodation .Egyptra travel service...
$15 Per Night
Cairo & Nile cruise with flight
Cairo, Egypt Sight-Seeing Tours
We are a reliable tour operator in Egypt since we established in 1988 for a comprehensive range of Travel services and Tailor-made programs upon request for Individuals and Groups. We arrange Incoming tourism, Historical and Cultural tours, Religious...
Starting at $666 Per Person
Beyond Egypt
Cairo, Egypt Sight-Seeing Tours
We Beyond Egypt are a professional travel agency with Skilled Staff, all Kinds of modern Transportation, multilingual Egyptologists, Wide Circle of Relationships at all Hotels, we are perfectly Qualified to offer you any Kind of service you dream of....
Starting at $50 Per Night
PRIVATE & Taylor-made travel in Egypt
Cairo, Egypt Sight-Seeing Tours
All our Tours are the Best Available for the lowest cost,All our tours are Available at any Time,Spendas Much Time at The Sites as you Wish To Do and See What you Want during your Stay in Egypt,Shore Excursions, Accessible Tours, Luxury Holidays...
Starting from $50 Per Night
|Link Code


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Melt your solid perfume directly onto your wrists and neck for an immediate dose of your favorite aroma. You can also rub some behind your ears and on the back of your knees.
Ladyboy solid perfume
Exclusive Perfume
0.4 oz
Product Actions
This product does not contain animal products of any kind.
This product does not contain animal products of any kind.
This product may melt if shipped to a warm location.
This product may melt if shipped to a warm location.
More from Exclusive Perfumes:
Androgyny never smelt so good
Va-va violet oil nestles next to chamomile and labdanum resinoid to coax out your inner Ladyboy. Some say it smells a little like banana, LUSH perfumer Mark says "The banana it's some kind of joke. The finished scent on the skin is sophisticated and contemporary in my opinion". Ours too! If Ladyboy could talk, it would shout 'variety is the spice of life!'
- Designed for bare skin: Lady Boy smells best when sprayed directly onto your body.
- From down South: The sexy scent was inspired by Brazilian beaches and their uninhibited inhabitants.
- Main notes: Banana, seaweed, violet, chamomile, labdanum and oakmoss.
Customer Review
from kc
"When you first smell this solid it's pretty heavy on the banana right away, but after a few seconds it mellows out and you can smell a hint of spice... Like a tropical spice... Amazing. Buy it & try it. I loved it."
Fresh ingredients
= Natural ingredients = Safe syntheticsOrganic Jojoba Oil (Simmondsia chinensis) , Castor Oil (Ricinus communis) , Candelilla Wax (Euphorbia cerifera) , Perfume , Chamomile Oil (Anthemis nobilis) , Labdanum Resinoid (Cistus labdaniferus) , Violet Leaf Absolute (Viola odorata) , Oakmoss Absolute (Evernia prunastri) , Seaweed Absolute (Fucus vesiculosus) , Talc , Titanium Dioxide , Methyl Ionone , *Limonene , *Linalool , FD&C Blue No. 1 , FD&C Yellow No. 5
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Featured Package:
Earl Klugh's, second annual Weekend of Jazz at Kiawah Island Golf Resort
November 10-12, 2011
Learn More
Join the Kiawah E-Club
- Unique Team-Building Ideas for Corporate Conferences and Events
- Kiawah Island joins in on Taste of the South
- From St John's High School to a world class resort!
- Kiawah Comedy Weekend
- LePore Family win the "Know the Kiawah Feeling" e-club sweepstakes.
- Kiawah's Special Winter Meetings Rates
- RSVP Tips for Planning a Successful Corporate Meeting at Kiawah
- Guerrilla Cuisine- A Dinner for Cystic Fibrosis
- A Kiawah Beverage Series with Bittermilk
- Kiawah offers great off-season special events
- Night Heron Kid's Pool Opens Tomorrow (Saturday, June 9th)! (10)
- Make a splash with the family next year in the new pools at Kiawah Island Golf Resort (10)
- Kiawah's Dir. of Outdoor Programs describes new Kiawah Pools (5)
- Kiawah's new 14-person Bay Boat for Kiawah River Tours (4)
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- Environmentalist Philippe Cousteau releases sea turtles from Kiawah beach (3)
- Thomas Creek Beer Dinner at Jasmine Porch Oct. 18th (2)
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BBQ, beach, beach vacation, birding, Charleston, Cherrywood BBQ & Ale House, Condé Nast Traveler, Dining, Earl Klugh, Easter, fine dining, Gourmet & Grapes, half marathon, Jasmine Porch, Jasmine Porch at The Sanctuary, Jonathan Banta, Kiawah, Kiawah Beverage Series, Kiawah Island, Kiawah Island Golf Resort, kiawah river, Lowcountry Cuisine, marathon, Mingo Point, naturalist, nature, Night Heron Park, Recreation, Sanctuary, Sommelier Garth Herr, South Carolina, spa, Tennis, The Atlantic Room, The Ocean Course, The Ocean Room, The Ocean Room at The Sanctuary, The Ocean Room at The Sanctuary at Kiawah Island Golf Resort, The Sanctaury at Kiawah Island Golf Resort, The Sanctuary, The Sanctuary at Kiawah Island Golf Resort, Tomasso, Tomasso at Turtle Point, Weekend of Jazz, Wells Gallery
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Tag Archives: tips
Sep 22
By Missy Hughes, Director, The Spa at The Sanctuary at Kiawah Island Golf Resort I have recently learned that pain is the loudest voice that the body uses to initiate change. There are several memos that it sends before getting … Read More
Sep 14
There's not a tennis player on the planet – including the current crop of all-time greats like Novak Djokovic and Rafael Nadal – who hasn't "choked" away a match. So don't feel too bad that you double-faulted on match point … Read More


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Have questions about SingleHop?
I'm here to help.
Call us toll free at 866.349.0689
- SingleHop
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Company Overview
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Why SingleHop?
Because when you host your business infrastructure with us, you get a lot more than just infrastructure. You get the capabilities of our award-winning platform and team, complete with a thoughtful methodology for designing, deploying, and managing your infrastructure, all built on a truly hybrid platform.
Choices and Flexibility
You can have a fully managed, fully unmanaged, or anywhere-in-between solution in any one of our strategically located, highly automated data centers.
- Fully Managed or Unmanaged
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With us, you can design, deploy, and manage any and all infrastructures from any of our global data centers through any device, at any time.
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All service requests are handled by our engineers in a timely manner with real-time monitoring and automated accountability through our Bill of Rights SLA.
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Contact SingleHop
SingleHop at a Glance
- Founded in 2006
- 14,000+ physical servers under management
- 3,200+ customers in 124+ countries
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Amsterdam 1 Data Center Details
Chicago 2 Data Center Details
SingleHop Network Design Overview
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Who is SingleHop?
SingleHop is a leading global provider of hosted IT infrastructure and Cloud computing. We are pioneering the global Cloud IaaS movement by enabling SMBs and service providers in the design, deployment, and management of a wide range of IT solutions.
Our management team is composed of leading professionals in a variety of fields.Learn More
Data Centers
We operate a number of strategically located, highly automated data center facilities.Learn More
We're always looking for enthusiastic and talented people to join our team in Chicago.Learn More
Our investors pave the way in order to make the company better every year.Learn More


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All Seasons Crepe Blazer: We took summer's best-selling linen blazer and remade it in color-rich crepe for all-year-round wear. Suit it with our matching short-sleeve sheath dress, pair it with pants or dress it down with jeans. You'll wear this blazer with everything!
Read what customers are saying about this product:
Rating: 5.00 out of 1 votes cast
Emerald Green Crepe Blazer
I love this blazer. I needed something really nice for an evening wedding and I really wanted the Lapis Blue but I since the blue one wasn't in stock I ordered the Emerald Green and it is absolutely beautiful. We had pictures made while at the reception and the picture is my favorite and it's all because of the Emerald Green dress and matching jacket. You won't be disappointed if you order this.
Burlington, NC
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If a delivery guy getting tased hits a little too close to home to be funny, try this video of legendary Melvins frontman King Buzzo wasting some richer peoples' time.
In the video, Buzz tries to buy an extremely large mansion (with a bowling alley) using nothing but his 'fame.' (His band infamously told a young Kurt Cobain that he wasn't talented enough to play guitar for them, but they remained friends and Nirvana cited Melvins as a huge inspiration on their sound)
All he does, however, is irritate the Realtor lady.


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By Charlie LeDuffFox 2 NewsDETROIT (WJBK) -- The 2012 crime numbers are in and they're horrible. Detroit suffered its second deadliest year in its history when taking the size of its population into account.Excluding three people killed by police in the line of duty, Detroit suffered 408 total homicides in 2012 with an estimated population of 695,000 people. The murder rate was only higher in 1987.Now Detroit Police officials want you to think it's really not so bad, removing 22 bodies from the official count claiming those killing as justifiable, but no other major American city does that, and even if you do, Detroit still suffered its second deadliest year."We've heard blame about guns, parents, the media, unemployment, poverty, what about the leadership in the department and the city? Does anybody in this room want to take any responsibility for spiraling crime?" I asked city leaders at a news conference."The problem lies not only solely with the police department, it lies with the press, it lies with the principal, it lies with the preacher, and it lies with the parent, so we have got to come together as a community and start to deal with this," said Interim Detroit Police Chief Chester Logan.Even with murder through the roof and non-fatal shootings up, as well, city leaders say there is good news."Our Detroit Police Department data show an overall decrease in major crime categories despite an increase in the homicide rate," said Mayor Dave Bing.But with the police department in disarray and precincts closed after 4:00 p.m., crime experts doubt even those numbers."I took a class in college in lying with statistics, you know, that's always been out there. I mean, you've got to really look yourself. I mean, you've got to really look hard at the raw numbers, and I think that's really where the answers lie," said Andrew Arena with the Detroit Crime Commission."People in Detroit know what's going on, and this continuing effort to downplay or to say that crime is down in Detroit or to correct the figures is wrong, and you can't correct it until you get accurate reporting of crime," said retired Detroit Police Sergeant David Malhalab.How does Detroit compare to other major American cities? We're the deadliest.According to city police sources across the country, here's a comparison of homicides:
*2012 is Detroit's deadliest year in per capita homicides. In 1987 the homicide per capita rate was 63.5/100,000.*With no plan on the horizon, the beat goes on in the Motor City. A cab driver was shot in the head Thursday morning. His colleagues came down to City Hall looking for answers from Mayor Bing."We came down here to let the mayor know that we want some police protection. Just don't put us out here and tell us to fend for ourselves. When we call the police department, we need for them to show up," said Peter Spivey, co-owner of Metropolitan Cab.They were turned away, but I gave them the answer that rank and file police had given me. In the end, it doesn't do any good blaming everybody else. We're going to need a plan. We're going to need police, and we need a change.
WFTC-TV11358 Viking DriveEden Prairie, MN 55344Phone: (952) 944-9999Fax: (952) 942-0455


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Today we are going to make Tiramisu. Make sure you have the following ingredients. This is going to be fun!
6 egg yolks
3/4 cup white sugar
2/3 cup milk
1 1/4 cups heavy cream
1/2 teaspoon vanilla extract
1 pound mascarpone cheese
1/4 cup strong brewed coffee, room temperature
2 tablespoons rum
2 (3 ounce) packages ladyfinger cookies
1 tablespoon unsweetened cocoa powder
Makes 1 - 7 x 11 inch dish
Enjoy your Tiramisu!
Get your Food & Drink recipes @ http://929wlmi.com/latest-updates/authors/34/
By Markus Mitterauer from Austria aka addicted [CC-BY-SA-2.0 (http://creativecommons.org/licenses/by-sa/2.0)], via Wikimedia Commons


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If you got a holiday gift from Target, and are looking to return it, their return policy has changed. It's stricter now when it comes to certain purchases.If you received an electronics gift for Christmas, you only have a few weeks left to return it to Target. Looking at the front and back of the receipt, you will see "90 days for a refund or exchange." But if you read on, it says "some items…have less than 90 days." According to Target's Web site those items are electronics like computers, tablets, cameras, videogames and no-contract cell phones. The expiration date for those - which is only 30 days now - is on the front of the receipt. If the gift was purchased between Nov. 1 - Dec. 25, the 30-day return period started December 26. If you want to return it, you better get to it. This stricter return policy started in September. It might not be a bad idea to double check your receipt for the return-by deadline.
Thanks for contacting FOX 5. To reach our newsroom by phone, please call (404) 898-0100.
KDFW FOX 4400 N. Griffin StreetDallas, Texas 75202
Main Station Directory:(214) 720-4444News Fax:(214) 720-3263 or (214) 720-3333


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Like us on Facebook for inter-esting movie poster-related stuff:
The Big Lebowski posterCopyright by respective production studio and/or distributor. Intended for editorial use only.
Directed by: Ethan Coen, Joel Coen
Cast: Julianne Moore, Philip Seymour Hoffman, Jeff Bridges, Steve Buscemi, John Goodman, Tara Reid, Peter Stormare, David Huddleston, Philip Moon, Mark Pellegrino


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Click a swatch below to change colors.
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Click here to get the current version.
District® - Juniors The Concert Tee DT5001
You're ready to jam in a tee that's as cool as the night's summer breeze.
Juniors Sizes: XS-4XL
Price: $11.96


text:
Taking Care of Your Diabetes When You Are Sick
- Home
- Health Information
- Taking Care of Your Diabetes When...
Test Your Blood Sugar Often
Test for Ketoacidosis
Stick to Your Routine
Take Your Temperature and Carefully Choose Cold Medicines
Monitor Your Cold
Get Your Shots
Make Your Sick Day Plan
- What blood glucose levels are considered high for you and when you should call the doctor
- How to adjust your medication to bring the blood glucose level back into the normal range
- How often you should test for ketones and when you should call the doctor
- What food exchanges you can make if you are not feeling well enough to eat your regular diet
- Which cold medications are safe for you
- Whether you have had your flu and pneumonia shots
American Diabetes Association http://www.diabetes.org/
National Diabetes Information Clearinghouse http://diabetes.niddk.nih.gov/
Canadian Diabetes Association http://www.diabetes.ca/
Public Health Agency of Canada http://www.phac-aspc.gc.ca/cd-mc/diabetes-diabete/index-eng.php/
Diabetes and Pneumonia: Get the Facts. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/diabetes/projects/pdfs/eng%5Ffacts.pdf. Accessed November 20, 2012.
Diabetic Ketoacidosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated February 3, 2012. Accessed November 20, 2012.
Take Charge of Your Diabetes. Center for Disease Control and Prevention website. Available at: http://www.cdc.gov/DIABETES/pubs/tcyd/ktrack.htm. Updated May 21, 2011. Accessed November 20, 2012.
Taking Care of Your Diabetes at Special Times. National Diabetes Information Clearinghouse website. Available at: http://diabetes.niddk.nih.gov/dm/pubs/type1and2/specialtimes.htm. Accessed November 20, 2012.
WhenYour Blood Glucose is Too High or Too Low. National Diabetes Information Clearinghouse website. Available at: http://diabetes.niddk.nih.gov/dm/pubs/type1and2/lowglucose.htm. Accessed November 20, 2012.
When You're Sick. American Diabetes Assocation website. Available at: http://www.diabetes.org/living-with-diabetes/treatment-and-care/who-is-on-your-healthcare-team/when-youre-sick.html. Accessed November 20, 2012.
Type 1 Diabetes. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary/. Updated September 2011. AccessedNovember 20, 2012.
Type 2 Diabetes. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary/. Updated September 2011. Accessed November 20, 2012.
Revision Information
- Reviewer: Brian Randall, MD
- Review Date: 11/2012 -
- Update Date: 11/20/2012 -


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Evidence-Based User Experience Research, Training, and Consulting
Get an inside look at the 10 best intranet designs of 2013 — this 373-page report is the only place to find this information, with 204 full-color screenshots of before and after designs, which are usually protected behind the organization's firewall.
Comprehensive case studies and detailed best practices keep you up-to-date on current trends and challenges, which you can use to improve your own intranet design.
The winning intranets were chosen by expert review based on design and usability, from a field of hundreds of nominations.
Article: 10 Best Intranets of 2014
Learn more about the winning teams
Eligible designs: Anything that runs inside a company and is not accessible on the public Web, including:
Purchase an individual license if the report or video will only be used by one person.
Customers who choose an individual license are not authorized to share the report or video with anyone else, or post it to any internal or external file server, website, or intranet. Individual License Terms
Purchase a group license if the report or video will be used by multiple people within your organization.
Customers who choose a group license are authorized to post the report or video on internal file servers or intranets and make it available to others within the organization. The group license does not grant permission to make the report/video available to people not employed by your organization, the general public, or to post it to a publicly accessible website or file server. Group License Terms×
Individual License
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Thanksgiving is a time to stop and be thankful for what you have but also consider those who are less fortunate.
That's why hundreds of volunteers are planning on buying, boxing, and delivering meals to those in need this year.
The Downtown Rescue Mission in Huntsville is in the middle of a massive project, and they're still looking for more help.
They're boxing up 876 food boxes, complete with turkeys for folks right here in the Valley.
This year, the need is much greater than usual.
"This year it's been a little bit more than usual. We're up about 20 percent over last year, and we really think it's due to the economic times we're going through right now," said Keith Overholt, President and CEO of the Downtown Rescue Mission.
If you want to donate time or money, the Downtown Rescue Mission is located at 1400 Evangel Drive in Huntsville.
Copyright 2012 WAFF. All rights reserved.
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Augusta, GA 30907
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EEO Report
Closed Captioning


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I did NOT realize what this was. Apparently it's swishing an organic oil (sesame/coconut/sunflower) in your mouth like mouthwash.
According to this article from the Huffington Post, it has amazing health benefits. It helps with your complexion, whiter teeth, cleaning up acne...kinda surprising if you ask me.
Have you ever heard of this?
Pretty interesting...and it might actually be cheaper than buying junk food?!?! Who knew?!?
I, DavidShankbone [GFDL (http://www.gnu.org/copyleft/fdl.html), CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0/) or CC-BY-SA-2.5-2.0-1.0 (http://creativecommons.org/licenses/by-sa/2.5-2.0-1.0)], via Wikimedia Commons


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text:
Dana, so sorry about the ear and the illness. I've heard elsewhere that that is the worst pain in the world.
Good luck Ash! I do hope you get accepted!!
Bridget, maybe some people are just making conversation. But it's also possible that many are taking it as a personal attack about their own choices. It happens all the time.
Work exploded on me again today. I had 1 good day. I'm so tense I have a pain in the top center of my back, just under my spine. I cannot continue on here. No more has been said since I sent the training link for SCCM to my boss. I think the nearly $2,000 made her change her mind.


text:
LEGO Shop Home Themes DUPLO® Tow Truck
Tow Truck
- Item: 6146
- Ages:2-5
- VIP Points: 0
- Pieces:17
- Retired product
Hit the road with the LEGO DUPLO Tow Truck with a functional crane and a mechanic to make repairs with the DUPLO accessories!
Repair the vehicles with the mechanic and his Tow Truck!
When a vehicle breaks down in LEGO DUPLO town, the helpful mechanic is always ready to help out. Whether he fixes it on the road or takes it back to his workshop using the powerful Tow Truck, you can always count on the mechanic to get the job done! Includes DUPLO Tow Truck and DUPLO mechanic figure.
• Includes LEGO DUPLO mechanic figure
• Vehicles include Tow Truck with functional crane
• Features tools, cone, road sign, flower and assorted DUPLO bricks
• Fix the vehicles!
• Drive the Tow Truck!
• DUPLO products are fun and safe for younger hands
• Measures over 6" (16cm) long, 2" (6cm) wide and 3" (10cm) tall
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|Episode Description
|Sunday, Feb 24, 2013 - 9:00 PM
"Page Eight"
In this story of files and sources, media and civil servants, Bill Nighy plays Johnny Worricker, an aging spy whose boss (Michael Gambon) plunks a file on Worricker's desk. When the contents are digested, Worricker notices a single revealing sentence on page eight that suggests significant cracks in Britain's intelligence operation. Ralph Fiennes plays the prime minister. Rachel Weisz is the enticing neighbor across the landing from Worricker. G
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text:
Researchers Discover a Unique Molecular Profile for
Lung Cancer
A team of researchers has found that the expression pattern of certain microRNAs (miRNAs) may predict tumor aggressiveness in some patients with lung cancer. These findings indicate that miRNAs may represent a new class of diagnostic and prognostic tools for lung cancer, according to study results in the March 13 Cancer Cell.
miRNAs are small segments of RNA thought to control gene expression. Their actions could change the expression of cancer-related genes within a cell and lead to malignancies.
The researchers identified two miRNAs - has-mir-155 and has-let-7a-2 - that could be used as prognostic indicators in patients with adenocarcinoma of the lung. High levels of has-mir-155 or low levels of has-let-7a-2 were associated with poor prognosis. Specifically, overexpression of has-mir-155 was the most significant indicator of this prognosis, independent of tumor stage. Although these miRNAs have been identified in other cancers, this is the first evidence linking has-mir-155 to lung cancer. Read more
Guest Update by Dr. Robert Croyle
NCI's Tobacco Control Research Yields Results
This is an exciting time in tobacco control research, particularly because of the excellent progress that has been made in smoking prevention and cessation.
Cigarette sales, for example, are at their lowest point in more than 5 decades. Our messages about the dangers of smoking and secondhand smoke exposure are being heard: more and more U.S. cities and states, not to mention many other countries, have passed laws that ban smoking in public establishments, including workplaces, restaurants, and bars. Read more
Researchers Discover a Unique Molecular Profile for Lung Cancer
A team of researchers has found that the expression pattern of certain microRNAs (miRNAs) may predict tumor aggressiveness in some patients with lung cancer. These findings indicate that miRNAs may represent a new class of diagnostic and prognostic tools for lung cancer, according to study results in the March 13 Cancer Cell.
miRNAs are small segments of RNA thought to control gene expression. Their actions could change the expression of cancer-related genes within a cell and lead to malignancies.
The researchers identified two miRNAs - has-mir-155 and has-let-7a-2 - that could be used as prognostic indicators in patients with adenocarcinoma of the lung. High levels of has-mir-155 or low levels of has-let-7a-2 were associated with poor prognosis. Specifically, overexpression of has-mir-155 was the most significant indicator of this prognosis, independent of tumor stage. Although these miRNAs have been identified in other cancers, this is the first evidence linking has-mir-155 to lung cancer.
A tumor with an overexpression of has-mir-155 or reduced expression of has-let-7a-2 would indicate the need for aggressive chemotherapy or radiation treatments. Other tumors that do not show high has-mir-155 or low has-let-7a-2 levels are less aggressive, and those patients might not require more therapy.
"This study is significant because it provides another tool for studying prognosis that is independent of tumor stage," said Dr. Curtis Harris, chief of the Laboratory of Human Carcinogenesis in NCI's Center for Cancer Research (CCR) and co-leader of this study. "Following surgery, 50 to 60 percent of patients with stage I lung cancer will develop metastatic disease within 5 years. This may indicate that there are micrometastases that have not been detected by imaging, scanning, or pathology.
"In the future, we can use miRNAs and other biological predictors to select patients who may need more aggressive treatment versus those who may not," Dr. Harris continued. "Additional studies confirming these results are the next step before incorporating miRNA analysis into routine clinical practice."
The study was a collaboration among researchers at Ohio State University Comprehensive Cancer Center, Jikei University School of Medicine in Tokyo, the National Cancer Center Research Institute in Tokyo, and NCI's CCR.
The researchers examined 104 pairs of primary tumor tissues and corresponding noncancerous lung tissues. Each tissue pair was obtained from the same patient to eliminate genetic differences between tumor and normal tissues.
Patterns of miRNA expression in each tumor and normal tissue pair were studied by microarray analysis. Five miRNAs displayed different expression levels in tumor tissues versus their controls and were selected for further study. Statistical analysis showed that patients with high has-mir-155 or low has-let-7a-2 had poorer survival than patients showing low has-mir-155 or high has-let-7a-2 expression. The difference in the prognosis of these two groups was highly statistically significant.
After examining tissue from lung cancer patients and following each patient to see how long they lived, researchers found that miRNA expression patterns were independent of tumor stage. When the scientists combined all clinical and molecular factors, they found that a high level of has-mir-155 or a low level of has-let-7a-2 was the most significant prognostic factor for an unfavorable patient outcome.
By Lynette Grouse
Guest Update by Dr. Robert Croyle
NCI's Tobacco Control Research Yields Results
This is an exciting time in tobacco control research, particularly because of the excellent progress that has been made in smoking prevention and cessation.
Cigarette sales, for example, are at their lowest point in more than 5 decades. Our messages about the dangers of smoking and secondhand smoke exposure are being heard: more and more U.S. cities and states, not to mention many other countries, have passed laws that ban smoking in public establishments, including workplaces, restaurants, and bars.
But new challenges continue to arise. As the spotlight article in this week's Cancer Bulletin illustrates, tobacco products themselves are scientific moving targets. In addition to so-called flavored cigarettes, products like hookahs and bidis appear to be gaining popularity, particularly among young people. Furthermore, tobacco use is rising in the developing world as it is declining in the U.S. With such trends threatening to slow or even reverse our hard-fought gains, complacency is not an option.
NCI is committed to ensuring that we continue to see significant declines in tobacco use. As part of this effort, NCI is engaged in and funding important programs and initiatives that tackle prevention and cessation from several angles.
Among these are several successful collaborative efforts with the Centers for Disease Control and Prevention (CDC). Most recently, we worked together to launch the national smoking cessation quitline. Since its launch in November 2004, 1-800-QUIT-NOW has received 213,000 calls. There are now quitlines in 45 states, and by the end of 2006 we expect that all states will have a quitline with access through 1-800-QUIT-NOW.
NCI and CDC partnered with the Robert Wood Johnson Foundation to launch a project called Helping Young Smokers Quit. This project has gathered information on a representative sample of youth smoking-cessation programs throughout the U.S. and will evaluate whether these programs have helped youth quit smoking.
On the international front, NCI, the Fogarty International Center, and other NIH institutes are working to support the successful International Tobacco and Health Research and Capacity Building Program.
In the prevention arena, NCI is funding work by Dr. James Sargent and colleagues at Dartmouth on the link between smoking in movies and youth smoking behavior. The latest study, published last November, found that young people who watched the most smoking in movies were almost three times more likely to begin smoking than their peers who watched the least smoking.
Dr. Sargent's research has spurred meetings between state attorneys general and movie industry groups to discuss ways to curb the amount of smoking in movies.
There also is the research led by Dr. Caryn Lerman at the Transdisciplinary Tobacco Use Research Center at the University of Pennsylvania, cofunded by NCI and NIDA, which is opening new windows into smoking cessation treatment.
Dr. Lerman's group is focused on improving pharmacotherapy for smoking cessation by analyzing the neurobiological pathways involved in nicotine dependence. They have identified a key brain receptor associated with nicotine's physiologic "reward," as well as a genetic variant associated with increased ability to quit smoking. This provides new leads to developing more effective individualized smoking cessation treatments.
As these examples illustrate, NCI is pursuing a comprehensive, multidisciplinary approach to tobacco control research. I'm extremely optimistic about our efforts. We can continue to reduce tobacco use and, more importantly, reap the resulting public health benefits.
Young Adults and Flavored Cigarettes: A Bad Combination
Tobacco counter-marketing campaigns have long focused on children and teenagers, both of whom have proven highly susceptible to the lure of cigarettes and smokeless tobacco. Several recent studies indicate that young adults - typically defined as those between the ages of 18 and 24 - also are at increased risk for smoking initiation or progressing from the occasional cigarette to everyday use. That's a dangerous trend, researchers say, because young adults already have one of the highest smoking rates compared with other age groups.
It's also of concern, some tobacco control and public health researchers contend, because multiple analyses of internal tobacco industry research and other documents suggest that the industry is actively trying to nurture the increased consumption of cigarettes among young adults.
The tobacco industry has recognized the importance of making inroads among 18- to 24-year-olds at least since the 1980s, says Dr. Pamela Ling, an assistant professor of medicine at the University of California, San Francisco, who has authored several studies on smoking and young adults.
Industry focus on this group expanded considerably in the 1990s, especially in the wake of the legal restrictions against advertising and other promotions geared toward minors in the 1998 Master Settlement Agreement between U.S. states and the major tobacco firms. In fact, since that time, she explains, spending on cigarette marketing has actually increased, with a heavy concentration on 18- to 24-year-olds.
"Even though we generally think of most smokers starting before 18, more and more are starting between 18 and 25," Dr. Ling says.
In one nationwide survey done in 1999, for instance, there were two times as many 18- to 19-year-olds just beginning to smoke as there were 18-year-old established smokers.
Young adults also have the highest rates of "someday" or "occasional" smoking, notes Dr. M. Jane Lewis of the University of Medicine and Dentistry of New Jersey's School of Public Health.
"They often call themselves 'social smokers,' and don't consider themselves smokers," she says. "But we also know that young adults tend to think, 'I'm just doing this for now and I'll quit later.' They underestimate the power of nicotine and addiction."
A New Lure: Flavored Cigarettes
Young adult-focused marketing is pervasive, Dr. Ling and other researchers argue, and includes cigarette promotions in bars and clubs (including in those that are, by law, smoke free), advertising in magazines predominantly read by those 18 to 34 (such as Cosmopolitan, Maxim, and Blender), and sophisticated Web sites.
These tactics have been heavily employed for one of the most recent cigarette innovations, flavored cigarettes, which several studies have concluded target minors and young adults as the primary audience.
Currently, only R.J. Reynolds is marketing flavored cigarettes. Called Camel Exotic Blends, they include regularly available flavors, such as Twista Lime and Kauai Kolada, as well as seasonal offerings, like Winter MochaMint.
"The look and feel of the marketing around flavored cigarettes really says 'young adults,'" argues Dr. Lewis, who co-authored a paper on the marketing of flavored cigarettes last month in the American Journal of Public Health (AJPH).
Typically packaged in brightly colored tins, the cigarettes have distinctive designs on them, making them ideal "badge products" that are highly visible in social situations, the AJPH study concluded. Magazine ads and other promotional items for Camel Exotics paint them as more hip than standard cigarettes, touting them as "sophisticated indulgences" that offer a more "pleasurable smoking experience."
Camel Exotics also has a Web site (for which users must register and verify they are 18) where visitors can find stores that sell Camel Exotics and get coupons or information on soon-to-be-released seasonal varieties or other special promotions.
On its corporate Web site, R.J. Reynolds addresses the development and marketing of its "specialty cigarettes" - which includes its flavored lines. A statement on the site notes that Camel Exotics only "represent 1/10th of one percent of our annual cigarette volume," and adds that, "Our one and only audience, regardless of brand or style, is legal-age adults who have made the decision to smoke."
A paper published last November in Health Affairs argued the opposite. Researchers from the Harvard School of Public Health and the Roswell Park Cancer Institute reviewed internal tobacco industry research and patents on flavoring technology, and concluded that flavored cigarettes are, in part, intended to play the role of "starter" cigarettes - a new way to promote a shift from occasional to daily smoking.
The Health Affairs paper is the only one to date that has analyzed how the cigarettes impart flavor. Camel Exotics, they found, rely on a small bead or pellet in the filters that delivers flavor and reduces or masks "the natural harshness and taste of tobacco smoke." Little is known about the flavor pellets, says Dr. Gregory N. Connolly, part of the team that conducted the Health Affairs study. And, he adds, it would be very difficult to do studies that could fully explain how these flavor pellets work and if they are associated with any additional health risks.
Although he agrees that more research is needed, Dr. Connolly argues that flavored cigarettes are a bad idea regardless of what any future research may find.
"One basic public health principle is you don't add sugar to rancid meat," he says, referring to the FDA's ban on that practice in the 1900s. "They've tinkered with these cigarettes to make them more acceptable and more addictive, to make it easier to start and harder to quit."
By Carmen Phillips
Thalidomide Effective in Myeloma, But No Survival Advantage
After 4.5 years, Dr. Bart Barlogie and colleagues from the University of Arkansas found that 56 percent of patients taking thalidomide had no adverse events - disease progression, relapse, or death from any cause - compared with 44 percent of controls following the same treatment regimen without the drug; and an even greater difference was seen in complete responses, 62 to 43 percent. But each group contributed comparably to the 190 patients who died during this time, "owing in part to significantly shorter survival after relapse in the thalidomide group," wrote the authors, 1.1 compared with 2.7 years. Further compromising the advantage for thalidomide were more serious adverse events, such as deep-vein thrombosis and severe peripheral neuropathy.
In an editorial, Drs. Michele Cavo and Michele Baccarani, of the University of Bologna in Italy, suggest one interpretation of the data was to reserve treatments such as thalidomide "for the sequential treatment of relapses as a means of controlling the growth or regrowth of tumor."
Biomarker Predicts Development of Precancerous Lung Disease
The circulating C-reactive protein (CRP) was shown to be an "excellent predictive" biomarker for progressive bronchial dysplasia - a precursor of lung cancer - in former and current smokers, according to a study in the March 1 American Journal of Respiratory and Critical Care Medicine.
The study, led by Dr. Don D. Sin of the University of British Columbia, measured baseline serum levels of CRP and other markers of inflammation in 65 subjects who had at least 1 site of bronchial dysplasia. The sites were also biopsied by the researchers. Additional bronchial biopsies at the same sites were taken 6 months later to determine if there was a worsening of the dysplastic lesions or new lesions.
"Half of the participants developed progressive dysplastic lesions after 6 months," the researchers report. "The baseline CRP levels in these participants were 64 percent higher than those without progressive disease." Among those with lower CRP levels (less than 0.5 mg/L), only 13 percent showed worsened conditions, compared with 54 percent with higher levels. "The odds of developing progressive disease were 9.6-fold higher in the latter than in the former group," the researchers add.
Although the results from the study need confirmation in larger, longer term trials, the researchers believe CRP, along with other prognostic methods, may be helpful in the urgent search for methods "to identify individuals harboring precancerous lesions and to use a chemopreventive agent to prevent progression of these lesions to invasive carcinomas." Currently, most lung cancer patients are diagnosed too late for effective surgical removal of the tumors, they note.
Cigarette Sales See Record Drop
U.S. sales of cigarettes dropped by 4.2 percent from 2004 to 2005, the largest single decrease in cigarette sales since 1999, the National Association of Attorneys General (NAAG) announced last week. More importantly, the NAAG reported, is that the 378 billion cigarettes sold last year represent the lowest sales figure since 1951; during that same period of time, the population of the United States more than doubled. The sales figures were compiled by the U.S. Treasury Department's Tobacco Tax Bureau.
Cigarette sales have declined 21 percent since 1998, the same year state attorneys general completed negotiations with the tobacco industry on the Master Settlement Agreement (MSA). The MSA imposed restrictions on a number of promotional and other activities in which tobacco companies could engage, including a prohibition on cigarette marketing and promotions aimed at minors.
"The continued enforcement efforts of the MSA's provisions by attorneys general, along with other health advocates, have made a marked difference in the number of smokers across the country, particularly among youth," said Iowa Attorney General Tom Miller, who co-chairs the NAAG Tobacco Committee, in a statement.
Mr. Miller also noted that states have sometimes been accused of not doing enough to slow tobacco sales because, under the MSA, part of the revenues from cigarette sales go back to the states. "Nothing could be further from the truth," he said.
Dr. Cathy Backinger, chief of NCI's Tobacco Control Research Branch, notes, "The decline in cigarette sales is good news for the American public. As cigarette sales decline, we can expect decreased tobacco-related deaths and health care costs."
Comprehensive Minority Institution/Cancer Center Partnership
Announcement Number: RFA-CA-06-011
Letter of Intent Receipt Date: March 20, 2006.
Application Receipt Date: April 19, 2006.
This is a renewal of RFA-CA-05-021 and will use the U54 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3360. Inquiries: Dr. H. Nelson Aguila - firstname.lastname@example.com; Dr. Peter Ogunbiyi - email@example.com; Belinda Locke - email@example.com
Cooperative Planning Grant for Comprehensive Minority Institution/Cancer Center Partnership
This is a renewal of RFA-CA-05-021 and will use the U56 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3361. Inquiries: Dr. H. Nelson Aguila - email@example.com; Dr. Peter Ogunbiyi - email@example.com; Belinda Locke - firstname.lastname@example.com
Feasibility Studies for Collaborative Interaction for Minority Institution/Cancer Center Partnership
This is a renewal of RFA-CA-05-021 and will use the P20 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3362. Inquiries: Dr. H. Nelson Aguila - firstname.lastname@example.com; Dr. Peter Ogunbiyi - email@example.com; Belinda Locke - firstname.lastname@example.com
Exploratory Collaborations with National Centers for Biomedical Computing
This funding opportunity will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3365. Inquiries: Dr. Jennifer Couch - firstname.lastname@example.com
Improving Diet and Physical Activity Assessment
This is a renewal of PAR-03-009 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3352. Inquiries: Dr. Amy Subar - firstname.lastname@example.com; Dr. Richard Troiano - email@example.com
Pilot and Feasibility Program in Urology
This is a renewal of PA-04-146 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3348. Inquiries: Dr. Suresh Mohla - firstname.lastname@example.com
Characterization, Behavior and Plasticity of Pluripotent Stem Cells
This is a renewal of PA-04-101 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3351. Inquiries: Dr. Neeraja Sathyamoorthy - email@example.com
Adjuvant Therapy for Stage II Colon Cancer
Name of the Trial
Principal Investigators
Why This Trial Is Important
In this trial, researchers are using molecular tests to help identify patients who are at high risk for recurrence after colon cancer surgery. Those deemed at high risk will receive adjuvant chemotherapy (drug therapy given after surgery to help suppress cancer recurrence). Half of the high-risk patients will also receive adjuvant treatment with bevacizumab, a monoclonal antibody that blocks the activity of a protein called vascular endothelial growth factor (VEGF). Tumors often produce large quantities of VEGF, which stimulates the growth of new blood vessels that help provide nourishment. Blocking VEGF may inhibit this new blood vessel growth and prevent continued tumor growth. Patients at low risk for recurrence will not receive adjuvant therapy but will continue to be monitored.
"Because patients with stage II colon cancer generally have good survivorship, it is hard to measure the impact of adjuvant therapy for these patients," said Dr. Benson. "This is one of the largest trials for patients with stage II colon cancer ever conducted, so we hope to determine conclusively whether or not adjuvant therapy is helpful. Additionally, this trial is the first of its kind to use molecular tests to determine how patients will be treated after surgery."
Who Can Join This Trial
Study Sites and Contact Information
An archive of "Featured Clinical Trial" columns is available at http://cancer.gov/clinicaltrials/ft-all-featured-trials.
At the March 7 NCI All-Hands meeting, Director Dr. Andrew C. von Eschenbach announced the establishment of the John P. Hartinger Executive Leadership Development Award, a scholarship that will be competitively awarded each year to an NCI employee who demonstrates leadership potential, a commitment to public service, and a desire to further his or her executive development. The award honors John Hartinger, associate director for Budget and Financial Management, who has served NCI for 38 years, mostly in the areas of budget and financial management. In addition to his many technical skills, which are widely known and admired across NIH, he has served as a role model, mentor, and teacher for many NCI staff.
Six NCI employees received NCI Director Gold Star Awards in recognition of special accomplishments. The awardees are: Dr. Christine Berg, Division of Cancer Prevention; Donna Bonner, Publications Support Branch; Christina Bruce, Office of Workforce Development; Dr. Steve Libutti, Center for Cancer Research; Dr. Linda Weiss, Cancer Centers Branch; and Dr. Jonathan Wiest, Center for Cancer Research.
CCCT Staff Appointed
Dr. Prindiville received her M.D. from Northwestern University and her M.P.H. from Johns Hopkins University. Following her residency training, she joined NCI as a program director in the Community Clinical Oncology Program. In 1996, she joined the faculty of the University of Colorado Health Sciences Center. She returned to NCI in 2002 and joined the CCR Genetics Branch where she directed the Clinical Cancer Genetics Program at the National Naval Medical Center Breast Care Center and served as a clinical investigator in NCI's Clinical Genetics Branch.
Prior to coming to NCI, Dr. Jaffe worked at a biotechnology firm directing a clinical evaluations lab where she was involved in getting FDA approval for a DNA-based diagnostic test for HER-2/neu. Dr. Jensen managed extramural clinical trials in bone marrow transplantation for NHLBI for 10 years before coming to NCI in 2003 to oversee the grants and contracts that support the early drug development program. Dr. Petryshyn, a biochemist and molecular biologist, previously served in NCI's Division of Extramural Activities' Resources Training and Review Branch, and was involved in the review of NCI's Cancer Centers.
CCCT will manage the implementation of all Clinical Trials Working Group initiatives. Additional information is available online at http://integratedtrials.nci.nih.gov/ict/.
Tucker Named Director of Human Genetics Program
Dr. Tucker received her M.D. from Harvard Medical School and completed her training in internal medicine and medical oncology at Stanford University. Since joining the NCI staff in 1978, she has focused on family and population-based studies of melanoma and other cancers in efforts to identify susceptibility genes and gene-environment interactions. Dr. Tucker was named chief of the Family Studies Section in 1987, became chief of GEB in 1992, and will continue to serve in that capacity. In her new role, she will share responsibility with the division director in managing and strengthening DCEG's intramural and collaborative research programs in cancer genetics.
HIV/AIDS Awareness Day Observed
Abramson Cancer Center of the University of Pennsylvania
Director: Dr. John H. Glick • 34th and Spruce Streets, Philadelphia, PA 19103 • Phone: 800-789-7366 • Web site: www.penncancer.org
Patient Care
Basic and clinical research is a cornerstone of the Abramson Cancer Center's operations. Current areas of research focus include:
Other Notable Programs


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I am finally ready. I am having my IUD out on 3/13, which gives me a little less than a month to complete my research and put together my plan.
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Level 0
Hints for the challenges will be asked and given in here.
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Make a donation and help keep the site running! -thesamet
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Falling at the first hurdle here.
I can do the computation. I can get to the next puzzle (although I think this is probably more of a challenge than solving the python, and certainly took me longer!). But I was completely stumped as to how I was supposed to view the solutions in the wiki. Perhaps you should have a level -1 "Question: the answer is 'cat'"* with an explicit walkthrough to spell out the mechanics for the duffers like me.
* "cat" is the answer to this one.
* "cat" is the answer to this one.
If the post-it note said "6x7", the url would be:
But it doesn't.
But it doesn't.
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text: We have seen from scripture that the ceremonies on the Day of Atonement symbolized the removal of sins that had accumulated in the sanctuary. It was a day of judgment. "For whatsoever soul it be that shall not be afflicted in that same day, he shall be cut off from among his people. And whatsoever soul it be that doeth any work in that same day, the same soul will I destroy from among his people" Leviticus 23:29, 30.


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Exchange student learns from the difference
Foreign exchange student, Barbara Yosino grew up with the influence of two cultures. Her parents are from Brazil and moved to Japan 20 years ago.
"I grew up in the Japanese culture and the Brazilian culture at the same time," she said. "Our household in Japan is different from the average Japanese household."Subscribe to Read!


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Dogs as Judges of Character
Do you value your dog's insights?
Please note comments are moderated. After being approved your comment will appear below.
Submitted by Laura | October 10 2012 | Permalink
This was a interesting article I will pass along to my husband.
The rescue lady saw her extreme reaction and decided not to let this man adopt the small puppy he wanted. When we asked her, she said something didn't feel right about him and with Lady's reaction too she trusted her gut. Her comment was "I've been doing this a long time, and if a dog is showing an odd reaction to someone, it's usually for a reason and they are trying to tell me something".
The end of the story is Lady is now our foster failure and stayed with our other three. She is a great dog and well on her way to being a canine good citizen graduate :)
Submitted by Jenn | October 17 2012 | Permalink
Laura, I'm so happy to hear about your "foster failure." I have two dogs of my own and have thought about fostering another, since city ordinances allow for up to three dogs in our home, but I just know I would never get past fostering my first. Once you bond with a dog, it's too hard to let them go. Especially one as good as Lady.
Submitted by Crystal | October 10 2012 | Permalink
We had a golden retriever/chow mix who was very friendly with most of the people my two sons brought home. When he would react to specific people in an unfriendly manner, those kids were bad news. The same thing with workmen that would be in our house when I was alone. He was a great judge of character.
Submitted by Liz | October 10 2012 | Permalink
I believe this 100%. My dog has a good gut-feel about people. Sometimes it's just that they're nervous about the dog, sometimes they have some other emotional turmoil going on. But if I don't know them, and my dog doesn't like them, I'm immediately on guard.
Submitted by citydog | October 10 2012 | Permalink
While I do think that many dogs are quite adept at spotting human insincerity/deception and will make note of unusual reactions (positive or negative) my dogs have to individuals, I really hate articles like this because they are often interpreted in such a way that it puts *FAR* too much responsibility on dogs to be mind readers. People unfairly expect dogs to know the difference between, say, a meter reader and a burglar, and then are surprised when the dogs bite (and of course, the dogs inevitably pay the price for that).
Submitted by Anonymous | October 10 2012 | Permalink
I have a little terrier x who is an EXCELLENT judge of character. 1. He has this uncanny ability to detect ANYONE in the vicinity who is afraid of dogs. He is a VERY friendly little pup but on 2 separate occasions as I was walking towards someone (friendly people) he had not had contact with yet - he started backing up and just barking - and on both occasions - these people said AFTER he started backing up and barking ..."oh..i'm very afraid of dogs". Also - in general - we can walk by people and not a peep out of him...but there is this ONE neighbor i have that...to me...seems harmless enough...but...my little dog wants to eat him up when he goes by ...he acts like the tasmanian devil. I had another dog that has since passed away that reacted the exact same way to this neighbor....not sure why....but...i try to steer clear of him. I think dogs are able to read very subtle physical behaviors/mannerisms and/or smell certain scents etc that humans can't...and that is what lets them know "good-bad" people - or "sick - healthy" or even "happy-sad" people -
Submitted by Dave Trowbridge | October 10 2012 | Permalink
I think that in many, if not most, cases, what your dog is reacting to is not its judgment of the person, but your subconscious judgment that social conditioning or other factors prevent you from recognizing or acknowledging.
Submitted by Aaron | October 10 2012 | Permalink
My dog, Ember ( a heeler/shepherd mix) is a celebrity in my neighborhood. She's pleasant with everyone she meets, listens when I tell her to stop chasing cats or squirrels and I occasionally walk her off- lead because shes so good at being....well, good. She's also well known for not barking...at anything. So much so that I've told my neighbors that if she is barking continuously to just call the police before checking it out. She's a great ambassador for canines everywhere.
About a year and a half ago. I was out on my back patio with a view of the courtyard. Ember is used to seeing dogs, cats, squirrels, kids and strangers regularly here. Shes content to observe closely but she never gets overly excited about anything except for the few nemesis kitty's running around.
A man and woman with a small child between them appear on the walkway about 150 feet away. Ember lost it. In the 5 years Ive had her, Ive never heard her bark at anyone before but there it was. Teeth bared and barkin her furry head off. I took her inside immediately and wondered if it could be the kid but that makes no sense. She loves kids.
From 150 ft out she sensed something wrong in the most innocent, unassuming scene you can imagine. I don't know what it was, but I trust her instincts nonetheless. Something was up with those people or one of them. I wish I could have a follow up story like the article, but I don't. Nothing like it has happened since.
I do put faith in my dogs instincts but that's my dog. Context is everything. The dogs normal responses, their past exposure to new environments and people all come into play. I do believe they have a sixth sense about these things but like any unknown, be skeptical.
Submitted by Anonymous | October 10 2012 | Permalink
I have a feeling for every time a dog reacts to someone due to a "correct judge of character" there will be twenty or so more times where a dog reacts due to poor socialization, gaps in socialization, poor handling skills or other common factors. While I wouldn't mind Karen London or other qualified people making this kind of commentary about their dogs, the public at large is not particularly qualified to make that judgement, IMO.
Submitted by Jan | October 11 2012 | Permalink
My dog is a certified therapy dog and loves everyone -- with the exception of a guy he encountered six years ago. He started growling and going nuts at this man(who responded by getting behind me and making a threatening move towards the dog). We later determined the guy was drunk, on drugs, or mentally ill (perhaps a combination of all three). I truly believe in trusting your dog's instincts and getting out of a situation where your dog is showing unusual behavior towards a person.
Submitted by chickwdog | October 15 2012 | Permalink
My new dog is leary around one of my husbands friends. He loves everyone except this one guy. I told my husband that I trust the dogs instincts towards this guy. There is "something" about him that just doesn't sit right with me either. I believe our dogs are our guardians and trust their judgement wholeheartedly.
Submitted by Szabo | October 16 2012 | Permalink
My rescued Vizsla bit the principal on graduation day.
I hadn't had him, the dog, long. He was off-leash (okay in that park,) and, the high school graduation was slated to occur on adjacent land. The dog was curious and approached a man who turned around and kicked at him (he missed) angrily telling the dog to go away. My new buddy reached up and snapped his jaws on the principal's cheek. Later I told the angry man that I'd probably bite too if he kicked me.
Submitted by Jenny H | July 18 2014 | Permalink
I dunno,
My German Shepherds seem to instinctively dislike people who are afraid of them. But this doesn't at all seem to correlate with people whom I have found to be untrustworthy.
The Kelies of he other hand love Anyone, just so long s they throw the ball, the stick, the mouldy lemon that they've dropped at the person's foot. My Mad Kelpie even loved the bloke who threw stones at him, and kept retrieving the stones and giving them back to the bloke to throw again.
But I didn't love him and told him off -- the Electricity People send a new meter-reader after that! :-)
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Contact Information and Permission Authorization Card - Spanish (10)
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Records personal information about each clubber. One form per child.
Información de contactos y permisos.
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Record clubbers' personal information such as birthday and contact information. Cards also provide space for notes from parents and communication details.
Información de contactos y permisos.