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For those who don't know me -- I'm Tracey from traceyjay quilts (and traceyjay quilts pattern shop)! I have one handsome husband, two sweet and adorable children, and I love to quilt when I have the time (which is rare these days!)
I made these two quilts for two sweet babies in my life (no, not my own). This little tutorial has been in the works a long time! I actually finished a second one for my niece (in Sunkissed) before the original was done. I hope you can forgive the delay; I would personally like to think I have a good excuse. ;) So -- even though these particular lines are now hard to find, I have no doubt this design would sew up beautifully in Reunion, the new Lucy's Crab Shack or even Mama Said Sew... as it already was adorable in two other Sweetwater lines.
I need to note for those who want to make one of their own -- there was a lot of "winging it" while making this quilt, and the measurements are not exact and precise in all ways. This tutorial is then my attempt to give you a bit of insight in to my (less than perfect, but hey they work) methods. I would not recommend this design for a first project, because you are working with so many bias edges, as well as oddly shaped setting triangles. If you're willing to exercise a little patience, I'm confident though that you'll love the results.
1 Jelly Roll (Pure by Sweetwater featured)
1 yd. contrast for sashing (will have some leftover for binding)
1 yd. for setting diamonds and triangles
1/2 yd. or charm pack for border
2 yards backing (might need more if sending quilt to a long-arm)
leftover jelly roll strips and sashing for binding
- Sort your jelly roll strips by dark, medium, and light value
- Group in to sets of five, following the pattern of dark/light/dark/light/dark and light/dark/light/dark/light. If your sashing is dark in value, you will need three sets with light on the outside, and two sets with darks on the outside. Switch if your sashing is light (like in the Sunkissed example), and make more groups with dark on the outside (twenty-five strips total, with thirteen light and twelve medium or dark -- reverse if using light sashing). The picture below shows a set of strips that are dark/light/dark/light/dark.
- Sew in to sets with a 2" off-set for each strip (see picture). There is no need to trim selvage. Press very well (either open or to one side; I alternated directions for the dark vs. light strip set)
|There is a quarter inch off-set when each section is joined to the next.
Setting triangles:
Start by making a template. I use freezer paper, but regular paper (or something else you choose) would work too. Trace the diamond on to the freezer paper, and cut it out.
Using the template, you need to make setting triangles for your sides, corners, and top/bottom. Depending on your fabric choice (if it is directional or not), you will need to pay attention to how you orient your template. I like freezer paper because I can just iron it down, and then use the rotary cutter to cut my setting triangle.
This picture also shows how your rows will be sewn together (diagonally).
Cut and piece 1 1/2" strips long enough for your length of sashings. You will need some "short" sashing strips (that go along the edge of the blocks/setting triangles in one direction, and some "long" (that go along the edge of the rows to join the rows together). Use your template, or measure the edge of your block, and make sure there is enough length to fully extend past the edge, so it can be trimmed later (this is important when dealing with bias edges.
Sew a length of sashing along the "short" edge of your setting triangles or block. The end of the sashing will extend past the end of the triangle or block. Use your ruler to trim the edge.
Here is the "short" piece of sashing trimmed.
When joining two blocks together along the "short" edges, use your quilting ruler and measure 2 1/4" from the edge (as shown in picture), and then trim the overhang of the sashing.
Piece your blocks and triangles together in diagonal rows, and then join diagonal rows to one another, with a long strip of sashing in between.
It can be tricky to join the rows of diamonds lined up when adding the sashing -- I pressed a 1/4" seam along one edge (similar to when joining the strip-pieced sections for the blocks), and then used a pencil to mark where the sashing needed to line up in order to make a straight line of the "short" edges. (This is another one of those spots I mentioned earlier where I did some "winging it," and you might be able to tell from the picture that particular seam was ripped at least once so I could get it right.)
Square up your top (I did not have precise measurements here -- I just did my best to even out all my edges!), add a 5" strip or pieced charm squares on each side, and you've got a quilt top!
Make your backing; Layer; Baste; Quilt; Bind -- Done!
For the variation of this quilt I did for my niece Libby, in Sunkissed, I framed each block with a coordinating solid, then sashed in white, used assorted fabrics for the setting triangles, and used a charm pack for the side borders. This makes for a bigger quilt overall -- just make sure you use the block WITH the framing to make your template for the setting triangles. The other steps for making this quilt are the same as described in this tutorial here.
A very "sweet" quilt measuring about 42" x 56"


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Taxpayers this week got an unexpected dividend from the conviction of Bobby Ferguson on racketeering charges -- cash, property and equipment worth up to $1 million.Nearly a year after the feds indicted Ferguson on public corruption charges in 2010, agents swarmed over his property and seized more than a dozen pieces of heavy equipment. Other searches turned up more than $460,000 in cash.While the jury deliberated, the feds and Ferguson signed a forfeiture stipulation, a document in which Ferguson agreed to give up his equipment, cash and property if he got convicted.On Monday, Ferguson got the bad news. A jury found him guilty of nine counts of public corruption, including bribery, extortion and racketeering.Soon the government will put up for sale the home that Ferguson's family has called home for years.The feds are also expected to sell Ferguson's condo at Riverfront Towers in downtown Detroit.His wife declined comment.While it's not up to prosecutors where the money from Ferguson's property will end up, there is a chance it could go to the city he cheated for so many years.If it ends up going to the federal government, the proceeds should be enough to cover the taxpayers' tab for the lawyers that defended Kwame and Bernard Kilpatrick.Ferguson's wife said she doesn't know what she will do when she has to leave her home. For now, she is just trying to process the emotions from a week that has to be the worst one in this family's lives.
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Click here if you are unable to view this video.
Published: August 31, 2013
(36) Karen (NC), September 30, 2014 5:55 PM
Yom Kippur: Coming Clean
(35) Anonymous, September 30, 2014 4:29 PM
(34) Nancy, September 30, 2014 1:34 PM
The ways in which we ask for help
(32) Anonymous, January 29, 2014 3:26 PM
Responses to Father Not Knowing and Punishing
I think that Mr. Harary's parenting techniques do not have to be ridiculed or criticized in such a public setting. If you are listening to his lectures, then you are obviously aware of this man's brilliance and ability to understand and relate to others. Don't you think he knows what he is doing as a father as well? Although I'm sure that your motives were truly sincere and coming from the best place, your comment was still unnecessary. Rather, focus on his meaningful message and attempt to live up to it...this video was about coming clean, rectifying your mistakes and being a better person. Yom Kippur was not too long ago-just because we are approaching Adar does not mean we are not required to act the same way we would by the Yomim Noraim time. We should not act in an undignified manner.
Kudos to Charlie Harary once again for an excellent video! Truly motivatating and encouraging! Thank you!


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From WENN.com
The stuntman will front Bam's Bad Ass Game Show on U.S. cable network TBS next year (14).
The new reality series will pit daring contestants against each other in unusual and dangerous challenges.
According to a release about the show, contestants will engage in ""incredibly demented, potentially dangerous and occasionally painful challenges,"" and the loser of each challenge will be eliminated until there is one sole survivor left standing.
Margera's Jackass pal Steve-O launched quirky game show Killer Karaoke last year (12). On his programme, members of the public have to sing their favourite songs while tackling stunts.


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1 large onion or 1.5 cups diced
5 cloves garlic, or 1.5 T minced
1 t cumin seeds (ground is OK)
1 t coriander
2 T chili powder
1/4 t oregano or marjoram
2 serrano chiles, seeded if less spice is desired, chopped
1 small green pepper or 3/4 c chopped
1 small red pepper or 3/4 c chopped
pinch salt/pepper
3 c black beans (28 oz can or 1 c dried. but if they're dried they
need to be cooked first)
4 c vegetable stock or water
2 bouillon cubes if not using stock
1/2 c quinoa, rinsed
15 oz can corn or 1.5 c frozen corn
14 oz can diced tomatoes, or better yet, Rotel
more stock/water if necessary
Juice of 1 large lime
2 c cilantro, chopped
salt/pepper to taste
In a heavy bottomed soup pot over medium heat, place the first 11
ingredients in the pan and saute for at least 10 minutes. Add the
beans and stock and quinoa and bring to a boil. Cover, turn heat down
to a simmer and cook for 20 minutes, then add the corn and tomatoes.
You may need to add more water to reach your desired thickness. I like
a super chunky stew. Turn heat to low and cover for 20 more minutes.
Stir in the lime juice and cilantro and season with salt/pepper to
This is delicious topped vegan sour cream mixed with roasted garlic,
lime juice and paprika, and some chopped avocado.
This morning, I awoke knowing I would have to figure out breakfast out of my pantry.. and my pantry is very bare with morning staples. I knew I had some cranberry and apple sauce in the freezer, so I took that out as soon as I woke up. I have about 1 cup of sucanat in this house, which I use for bread making a tablespoon at a time... so no pancake syrup could be made... but I have stevia... and oats and white whole wheat flour, so threw together these awesome muffins. I only used 2 T EVOO for the fat, along with flax meal..
My son enjoyed his slathered with peanut butter and jelly and washed it down with a huge glass of soymilk. I only wish I had written down the ingredients and proportions because they were delicious!
The other day I wanted to make my delicious veggie cream cheese spread, but didn't want the calories of the cashews. I tried my hand at this awesome tofu based spread with no added fat. It was delicious! I also used it to top whole wheat pasta (no pic).. I am going to make it one more time and measure so I can get the new and revised low fat version out to my testers!
In the theme of utilizing my pantry ingrendients, I made some seitan pepperoni... and steamed it based on the awesome Julie recipe. I am planning on making her sausages as written one of these days.. I just need to get to the health food store for some spices first as I want to do it exactly as writen.
I used the "seitanroni" to top this pizza.. it also had sauted mushrooms, onions and peppers and was topped with soft tofu/cashew cheez...
Lately I've been enjoying plain popcorn... I don't even use oil, just a quick spray of olive oil... 3 T of the dry corn equals around 4 cups popped for 130 calories.. and it's really good. I used to hate popcorn, but I think I really hated the chemicals, salt and fat in the commercial stuff. I don't have a microwave, so everything has to be made from scratch... which is a VERY good thing.
Last but not least... my sweet baby. She is sleeping at momma's house tonight!! We have gone for 2 walks at the beach... and it's just awesome. I love it when she spends the night.


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Training and Event Calendar
This event calendar is provided as a service to our members and the public. An event may be cancelled at any time. Please confirm the event with the sponsor prior to making travel plans. To submit an event, please contact us.
March 2014
Louisiana Protective Order Registry Legal Seminar @ Natchitoches, LA
March 7, 2014 @ 8:00 am – 12:30 pm
The LPOR Legal Seminar will: Explain how the protective order registry works. Explain the appropriate use of the mandatory order forms. Identify and discuss state [...]


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The Lions got a major piece of business off their to-do list as Matthew Stafford has agreed to a 3-year contract extension. Coupled with the two years he has remaining on his current deal, this locks up the team's quarterback for the next five years.
According to various reports the money is somewhere between $75-$77 million on the pact that runs through the 2017 season. Approximately $43 million will be guaranteed in the new contract.
In my opinion this makes sense on a number of levels. First and foremost, this locks up the teams franchise quarterback for the next 5 years. It gives the organization some cap relief in the short term and also numbers to work with moving forward.
If Stafford is the player the organization believes he is, the two sides can work out a career closing deal after this one. Stafford will only be 29 when this contract ends, so for him it could mean another huge contract down the line.
If Stafford was to regress or not turn into the player the Lions envision, then they can go their separate ways at some point in the future.
It doesn't seem like there is a great deal of risk for either side. The Lions have their guy through 2017, Stafford adds more years and more money to his current deal and nobody has to worry about this heading into a big season.


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Studying history provides access to the whole world; not just to
the past, but to the present that grew out of the past. The
study of history equips students with analytical skills and
research techniques of great practical value in both educational
and career settings. The program is designed to acquaint students
with different ages, societies and cultures, and to develop their
strengths in writing and thinking.
In organizing the curriculum, our distinguished faculty has
provided students with a broad knowledge of history and a firm
foundation for graduate school or careers in business, government
service, law, and education. Practice and theory are linked through
internships at the many historical sites available to us in the
Hudson Valley.
Minor in History: Students who minor in history
must take 18 credits in the discipline. Three credits may be in
political science and at least nine of the credits must be in
courses at the 3000 or 4000 level.
College professor, lawyer, archivist, elementary school teacher,
high school teacher, law enforcement officer, government official,
foreign service agent, state department analyst, politician,
journalist, stock broker, corporate records manager, political
pundit, bank manager, historical site manager, museum curator,
military officer, and many other options.
Visit the American Historical Association's page on
Careers for History majors.
Please contact the Office of Adult Degree Completion at
845-569-3223, or email firstname.lastname@example.com
with any questions, or for further information.
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DANCING WITH THE STARS - "Episode 1608" - Six remaining couples take to the dance floor, MONDAY, MAY 6 (8:00-10:01 p.m., ET) on ABC. For the first time this season, each couple will perform two routines in an effort to impress the judges and earn America's votes. (ABC/Adam Taylor) TOM BERGERON, KARINA SMIRNOFF, JACOBY JONES
Use a Facebook account to add a comment, subject to Facebook's Terms of Service and Privacy Policy. Your Facebook name, photo & other personal information you make public on Facebook will appear with your comment, and may be used on ABC's media platforms. Learn more.


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Gold standard: Celebrated animated films
Published On: Jul 06 2012 10:42:29 AM PDT Updated On: Jul 17 2014 07:23:49 AM PDT
As "Planes: Fire and Rescue" opens in theaters this week take a look at some of the top animated films of the last decade.
The views expressed are not those of this company or its affiliated companies. By posting your comments you agree to our Terms of Use.


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A lot of you are probably happy that disgraced Detroit Mayor Kwame Kilpatrick is going to spend most of his life in federal prison. I don't like people that steal from me and my children either.A lot of you probably think that Detroit's corruption started "40 years ago" -- that's code for Coleman A. Young, Detroit's first black mayor and a Democrat. But what if I told you it is not just a Democrat thing? It's not just a black thing. It is also a white thing, a Republican thing. That it's our thing.Over the past 80 years, five Detroit mayors and four county executives have either been sent to prison, were the subjects of federal probes, or were removed from office.It's true. And so here it is: a primer on Detroit municipal corruption.The year was 1929, Republican Charles E. Bowles was elected mayor of Detroit after running on the law and order platform. Prohibition was in full bloom and a mafia gang war raged. With ties the Klu Klux Klan and the Purple Gang, Bowles did little to stop it. Blood flowed in the streets. Bodies stacked up like cord wood. A successful recall campaign was launched and Bowles was removed from office after just six months. On the night of his removal, Jerry Buckley, a popular radio show host who bitterly fought for Bowles' removal, was shot dead from the hotel lobby from where he broadcast. Kilpatrick isn't even the biggest corruption scandal to rock Detroit.In 1939, a woman named Janet McDonald dressed her 11-year-old daughter Pearl in a pink party dress and murdered her before killing herself. She left behind letters addressed to the newspapers, charging that her boyfriend was a bag man for the mob. The payoffs to top city officials were detailed. Those letters left to the indictment of 135 people, among them Republican Mayor Richard Reading, who was known as "Double Dip Dick" because he also demanded kickbacks for his son. He was convicted in 1942 of conspiring to take bribes from Detroit's underworld. He was sentenced to five years in prison.County prosecutor Duncan McCray was also convicted of accepting bribes from organized crime, as was county sheriff Thomas Wilcox, a long and lanky man who sported a diamond encrusted badge paid for by involuntary contributions from staff members. Also sent to prison were two county auditors, a precursor to the Wayne County executive who sold meat and cleaning solvent contracts to the highest bidder.Louis Miriani was the last Republican mayor of Detroit, serving from 1957-62. Called the "do-nothing mayor," he liked to invest in savings bonds and that's how the IRS caught him with hundreds of thousands of dollars worth in a family safe. He was convicted of tax invasion committed while he served as mayor unable to explain how he earned $250,000 on a $25,000 a year salary. He served 10 months in federal prison.Coleman A. Young was a Democrat and Detroit's first black mayor. In office for 20 years from 1974 to 1994, Young is the city's longest serving mayor. He declined to run for a sixth term, citing declining health. But FBI wiretaps and federal convictions of Young's chief of police and a business associate over stolen drug money and his links to a company that sold South African rands did little to help Young's re-election chances.Livonia Democrat Ed McNamara was the Wayne County executive from 1987 to 2002. His political machine played a significant role in the election of Kwame Kilpatrick in 2001. In fact, Kilpatrick's father Bernard was a major McNamara aide. But Big Mac is most remembered for the billion dollar expansion of Metropolitan Airport and the federal investigation that ensued. A prominent aide was convicted for taking kick backs, but the probe ended with McNamara's death in 2006. McNamara was followed into office by fellow Livonia Democrat Bob Ficano. The subject of both a federal and county corruption probe, Ficano has doled out sweetheart pensions even as the pension fund has collapsed. With the county on the verge of bankruptcy, Ficano's failed super jail project will most likely be bulldozed costing the taxpayers more than $400 million. The FBI is investigating a pay-to-play between Ficano and contractors and a one-man grand jury is considering charges of fraud, misconduct and neglect of duty in connection with the jail. Incredibly, Ficano says he'll run for re-election. So as I said, corruption is neither black nor white, Democrat nor Republican. It's all of it.It's politics.It's Detroit.It's America.And it's wrong.If Kwame Kilpatrick can do any good for society, let it be this: you serve the public, you don't steal.It's over. Or is it?
WTTG FOX 5 & myfoxdc5151 Wisconsin Ave. NWWashington, DC 20016Main Number: (202) 244-5151Newsroom: (202) email@example.com


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Saturday, 28 Aug 2010 08:09 PM
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Support for Scottish independence amounts to 46 percent of the electorate with 54 percent wanting to stay in the United . . .
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Ukraine President Petro Poroshenko implored Congress for assistance Thursday, warning peace in Europe depended on a forc . . .
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The scandal-scarred NFL must have zero tolerance for players who beat their spouses or abuse their kids- and have the . . .
Oh, I hope Silver is wrong. I really do. We can't stand another season of a...
So will Obama be known in history as the man responsible for World War 3?
Poor old Democrats; shaking in their boots over the midterm elections. Just...
The only way to end this is to kill every last one of these Muslims. They will...
Attn: to Ben Carson and Bill O'Reilly.
The operative "word of the day" should...
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Friday I had a dental appointment, just a regular cleaning. Anyone who knows me knows that one thing I take very seriously is dental care. Especially during pregnancy because there are so many common dental issues that women have during pregnancy.
Tooth decay is a real problem for women who have trouble with morning sickness. The acid from vomiting can cause your teeth to decay. But in general during pregnancy you have more acid in your mouth that can cause this too.
Loose teeth can be a problem caused by increased progesterone affecting the ligaments and bones.
Gum disease is the most common problem affecting pregnant women. Hormonal changes can cause gingivitis and that can lead to preterm birth if left untreated.
My dental appointment went really well. My hygienist and dentist were both very happy with the condition of my gums. I've been through this before so my dentist gave me some tips when I was pregnant with Mia. He told me to brush with a soft bristle toothbrush and massage my gums, floss daily, and rinse with a fluoride mouthwash.
Some women who have morning sickness have a hard time with the strong minty flavor of toothpaste so the suggestion for that is to use a child's toothpaste with a mild flavor. It doesn't have all the fancy whitening power or be the powerful breath freshener that an adult toothpaste would be, but at least it's cleaning your teeth. Another tip for women with frequent morning sickness; rinse with a baking soda and water solution (1 teaspoon baking soda to one cup water) this will help cut down the acidity in your mouth to prevent tooth decay.
During pregnancy it's important to see your dentist, but the best time to do so is the second trimester. In the first trimester and late in the third a visit to your dentist isn't best for your baby. All dental procedures should be postponed until after baby is born. It is important to let your dentist know that you are pregnant so they know what they should and shouldn't do, like x-rays.
If you have any dental concerns during your pregnancy talk to your dentist or ask your regular doctor.
Dental health can affect the health of your baby so you need to make your ob/gyn know if you are having any issues.
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These Sloggi briefs are perfect for the woman who loves maximum comfort when it comes to her underwear. The soft cotton fabric makes these ladies briefs a great everyday underwear option. The high rise waist flatters while the full bottom coverage looks smooth under clothing.
Wear these Sloggi maxi briefs with a Sloggi Double Comfort bra for the ultimate in everyday comfort.
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Pair these Sloggi Tai classic fit ladies briefs with a matching Sloggi Double Comfort bra.
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X-Hose Pro®
Reversible Bedspread
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Internet address & password log-book keeps track of all your favorite websites, passwords and usernames. This compact, spiral-bound book has tabbed alphabetical pages with plenty of room to organize and list all the information you don't want to risk forgetting! 144-page hardcover book has a stretchable band closure. 4¼"W x 5"L.
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I will give you 1,000 acres of land on Planet Orgy for your people if you aid us in this military conflict.
Moderator: Colette
lrdofbricks wrote:Shaeph wrote:I lost the game
shit. that means I lost the game to.
Bonn-o-Tron wrote:Needless to say, I've had The Game ruined for me.
tahthing wrote:WHAT IS THE GAME
Warhead wrote:my head burns with War.
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Minden Fire Chief Kip Mourad responded to a call for help earlier this week, when he was asked by the Joint Task Force Commission to send as much equipment and as many volunteers as could be spared to aid areas in south Louisiana affected by then-Hurricane Isaac.
"It's great that our city is willing to let us send our guys down there to help out," Mourad said. "I know our residents would appreciate other departments and volunteers coming to our aid, if we should ever need it. And that is what it is all about – helping each other."


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By Abbey Stone, Hollywood.com Staff
The nominees for the 2013 Grammy Awards will be announced tonight for the first time in a flashy, live concert at Nashville's Bridgestone Arena hosted by Taylor Swift and LL Cool J that will feature performances by fun., The Band Perry, Maroon 5, Janelle Monae, The Who and others.
While previous years' Grammys have been dominated by a single powerhouse artist or album (I'm lookin' at you, Adele), this year it could be anyone's game. Will Billboard sensations Justin Bieber and Rihanna get nods, or will indie darlings like Frank Ocean, Mumford and Sons, and The Black Keys rule the night? I guess we just have to wait and see!
Check back at 10:00 PM ET as we reveal the nominees along with CBS' broadcast.
Best Pop Vocal Album
Kelly Clarkson, Stronger
Florence and The Machine, Ceremonials
fun., Some Nights
Maroon 5, Overexposed
Pink, The Truth About Love
Record of the Year
""Lonely Boy,"" The Black Keys
""Stronger (What Doesn't Kill You),"" Kelly Clarkson
""We are Young,"" fun. featuring Janelle Monae
""Somebody That I Used to Know,"" Gotye featuring Kimbra
""Thinkin Bout You,"" Frank Ocean""We Are Never Ever Getting Back Together,"" Taylor Swift
Best New Artist
Alabama Shakes
Hunter Hayes
The Lumineers
Frank Ocean
Country Solo Performance
""Home,"" Dierks Bently
""Springsteen,"" Eric Church
""Cost of Livin,"" Ronnie Dunn
""Wanted,"" Hunter Hayes
""Over,"" Blake Shelton
""Blown Away,"" Carrie Underwood
Album of the Year
El Camino, Black Keys
Some Nights, fun.
Babel, Mumford and Sons
Channel Orange, Frank Ocean
Blunderbuss, Jack White
Song of the Year
""The A Team"" Ed Sheeran (songwriter: Ed Sheeran)
""Call Me Maybe"" Carly Rae Jepsen (songwriters: Tavish Crowe, Carly Rae Jepsen & Josh Ramsay)
""Adorn"" Miguel (songwriter: Miguel Pimentel)
""Stronger (What Doesn't Kill You)"" Kelly Clarkson (songwriters: Jörgen Elofsson, David Gamson, Greg Kurstin & Ali Tamposi)
""We Are Young"" fun. featuring Janelle Monáe (songwriters: Jack Antonoff, Jeff Bhasker, Andrew Dost & Nate Ruess)
Best Pop Duo/Group Performance
""Shake It Out"" by Florence + The Machine
""We Are Young"" by fun. featuring Janelle Monáe
""Somebody That I Used To Know"" by Gotye featuring Kimbra
""Sexy And I Know It"" by LMFAO
""Payphone"" by Maroon 5 & Wiz Khalifa
Best Pop Solo Performance
Adele, ""Set Fire to the Rain (Live)""
Kelly Clarkson, ""Stronger (What Doesn't Kill You)""
Carly Rae Jepsen, ""Call Me Maybe""
Katy Perry, ""Wide Awake""
Rihanna - ""Where Have You Been""
Best Dance Recording
Avicii, ""Levels""
Calvin Harris feat. Ne-Yo,""Let's Go""
Skrillex feat. Sirah, ""Bangarang""
Swedish House Mafia feat. John Martin, ""Don't You Worry Child""
Al Walser, ""I Can't Live Without You""
Best Dance/Electronic Album
Steve Aoki, Wonderland
The Chemical Brothers, Don't Think
Kaskade, Fire & Ice
Skrillex, Bangarang
Best Rock Performance
Alabama Shakes,""Hold On""
The Black Keys, ""Lonely Boy""
Coldplay, ""Charlie Brown""
Mumford & Sons, ""I Will Wait""
Bruce Springsteen, ""We Take Care of Our Own""
Best Hard Rock/Metal Performance
Anthrax, ""I'm Alive""
Halestorm, ""Love Bites (So Do I)""
Iron Maiden, ""Blood Brothers""
Lamb of God,""Ghost Walking""
Marilyn Manson ,""No Reflection""
Megadeth, ""Whose Life (Is It Anyways?)""
Best Rock Song
Jack White, ""Freedom at 21""
Mumford & Sons, ""I Will Wait""
The Black Keys, ""Lonely Boy""
Muse, ""Madness""
Bruce Springsteen, ""We Take Care of Our Own""
Best Rock Album
The Black Keys, El Camino
Muse, The 2nd Law
Coldplay, Mylo Xyloto
Bruce Springsteen, Wrecking Ball
Jack White, Blunderbuss
Best Alternative Music Album
Fiona Apple, The Idler Wheel Is Wiser Than the Driver of the Screw and Whipping Cords Will Serve You More Than Ropes Will Ever Do
Bjork, Biophilia
Gotye, Making Mirrors
M83, Hurry Up, We're Dreaming
Tom Waits, Bad As Me
Best R&B Performance
Estelle, ""Thank You""
Robert Glasper Experiment feat. Ledisi, ""Gonna Be Alright (F.T.B.)
Luke James, ""I Want You""
Miguel, ""Adorn""
Usher, ""Climax""
Best Traditional R&B Performance
Anita Baker, ""Lately""
Beyonce, ""Love on Top""
Melanie Fiona, ""Wrong Side of a Love Song""
Gregory Porter, ""Real Good Hands""
SWV, ""If Only You Knew""
Best Urban Contemporary Album
Chris Brown, Fortune
Miguel, Kaleidoscope Dream
Frank Ocean, Channel Orange
Best R&B Album
Robert Glasper Experiment, Black Radio
Anthony Hamilton, Back To Love
R. Kelly, Write Me Back
Tamia, Beautiful Surprise
Tyrese, Open Invitation
Best Rap Performance
Drake feat. Lil' Wayne, ""HYFR (Hell Ya F---ing Right)""
Jay-Z & Kanye West, ""N---as In Paris""
Kanye West feat. Big Sean, Pusha T & 2 Chainz, ""Mercy""
Young Geezy feat. Jay-Z & Andre 3000, ""I Do""
Best Rap/Sung Collaboration
Flo Rida feat. Sia, ""Wild Ones""
Jay-Z & Kanye West feat. Frank Ocean & The-Dream, ""No Church in the Wild""
John Legend feat. Ludacris, ""Tonight (Best You Ever Had)""
Nas feat. Amy Whinehouse, ""Cherry Wine""
Rihanna feat. Jay-Z, ""Talk That Talk""
Best Rap Song
Nas, ""Daughters""
Wale feat. Miguel, ""Lotus Flower Bomb""
Kanye West Featuring Big Sean, Pusha T & 2 Chainz, ""Mercy""
Drake feat. Lil' Wayne, ""The Motto""
Jay-Z & Kanye West, ""N---as In Paris""
Snoop Dogg & Wiz Khalifa Featuring Bruno Mars, ""Young, Wild & Free""
Best Rap Album
Drake, Take Care
Lupe Fiasco, Food & Liquor II: The Great American Rap Album, Pt. 1
The Roots, Undun
Nas, Life Is Good
Rick Ross, God Forgives, I Don't
2 Chainz, Based on a T.R.U. Story
Best Country Song
Carrie Underwood, ""Blown Away""
Ronnie Dunn, ""Cost of Livin' ""
Eli Young Band, ""Even If It Breaks Your Heart""
Alan Jackson, ""So You Don't Have to Love Me Anymore""
Eric Church, ""Springsteen""
Best Americana Album
The Avett Brothers, The Carpenter
John Fullbright, From the Ground Up
The Lumineers, The Lumineers
Mumford & Sons, Babel
Bonnie Raitt, Slipstream
Best Blues Album
Shemekia Copeland, 33 1/3
Dr. John, Locked Down
Ruthie Foster, Let It Burn
Heritage Blues Orchestra, And I Still Rise
Joan Osborne, Bring It on Home
Head to Grammy.com for the nominees in all 81 categories!
Follow Abbey Stone on Twitter @abbeystone
[Photo Credit: FREDERIC J. BROWN/AFP/Getty Images]
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Frosted Flowers in a Box
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This box arrives with your choice of either 6 or 12 of our NEW Flower shaped hand-frosted cookies!
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|Link Code


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Product Recall: We are voluntarily recalling fewer than 8,000 cases of regular Kraft American Singles Pasteurized Prepared Cheese Productlimited to 4 SKUs on two "Best When Used By" dates of February 20, 2015 and February 21, 2015. Click Here.
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State Comptroller Kevin P. Lembo says the state's mushrooming budget deficit has jumped by another $50 million, bringing the official deficit figure today to $415 million.
However, because of a technical accounting glitch, Lembo's office has not factored in to that figure Gov. Dannel P. Malloy's recently ordered budget cuts, the Connecticut Mirror reports.
When those cuts are calculated, the website reports, it brings the actual deficit closer to $290 million.
Malloy's office, meanwhile, is questioning Lembo's deficit figures. Malloy officials say they don't believe the deficit is as high as Lembo is estimating, but offered no reason for why they don't agree with the comptrollers calculations, the Mirror reports.
Lembo said the state's budget woes are, in part, the result of higher than expect spending on Medicaid. Malloy has said he will file a deficit mitigation plan with the legislature before year's end. He has blamed the state's fiscal problems on the enduring and lingering impacts in Connecticut of the nation's economic downturn.
In an effort to lower the deficit, Malloy last week announced $170 million in budget cuts, the maximum allowed by a governor without needing legislative approval.


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UNDATED (WSAU) - It just wasn't a good day to be on the school bus. Two separate incidents involving school buses happened Friday.
Fire caused extensive damage to a Minocqua bus. This happened as the driver was about to begin her morning route at around 6:40 a.m. She noticed smoke in the back of the bus and pulled over just as the fire started. A rear heater is the suspected cause. The driver was not seriously injured, but examined at Ministry Howard Young Medical Center as a precaution.
A different bus was involved in a crash during the morning route in Vernon County near Wheatland. The driver and four students were injured when the bus collided with another vehicle in a church parking lot. Three of the students went to the hospital with non life-threatening injuries. A total of 12 children were on the bus at the time. Visibility was poor due to heavy fog at the time. This crash remains under investigation.


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Model More Accurately Estimates Breast-Cancer Risk in African Americans
A new model published online November 27 in the Journal of the National Cancer Institute (JNCI) more accurately estimates the risk of invasive breast cancer for African American women than the current NCI Breast Cancer Risk Assessment Tool.
The NCI tool is widely used for determining both risk for individual women and enrollment eligibility for clinical trials of breast cancer prevention agents, but was developed using data collected primarily from white women. Read more
Communications and Education: A Critical Part of NCI's Mission
NCI has always placed a considerable premium on communication and education - a philosophy that grew in prominence following the passage of the National Cancer Act, which directed NCI to develop methods for ensuring important research findings were disseminated to researchers and to the public.
By reaching out to the public, researchers, policy makers, nonprofit organizations, and advocates, NCI can have a more robust conversation about our priorities, accomplishments, and challenges. We do it through state-of-the-science symposia, our award-winning Web site, the NCI Cancer Information Service, numerous publications, advocacy teleconferences, science writers' seminars, and much more. Read more
Model More Accurately Estimates Breast-Cancer Risk in African Americans
A new model published online November 27 in the Journal of the National Cancer Institute (JNCI) more accurately estimates the risk of invasive breast cancer for African American women than the current NCI Breast Cancer Risk Assessment Tool.
The NCI tool is widely used for determining both risk for individual women and enrollment eligibility for clinical trials of breast cancer prevention agents, but was developed using data collected primarily from white women.
Researchers have long been concerned that the NCI tool may not be as precise in predicting risk for African American and other nonwhite women, and the online version of the tool currently conveys this concern in a disclaimer.
"A lot of the original work was done using white women and validated using white women, and there is a need for studies of this type to either validate or develop specific models for other groups," says Dr. Mitchell Gail, from NCI's Division of Cancer Epidemiology and Genetics, lead author of the JNCI paper and developer of the original model behind the NCI risk-assessment tool, known as the Gail model.
Researchers based the new model on data collected for the Women's Contraceptive and Reproductive Experiences (CARE) study, from 1,607 African American women diagnosed with breast cancer and 1,647 African American women without breast cancer. Information was available for all participating women on the risk factors used to compute the Gail model: age at the start of menstruation; age at first live birth; number of previous benign breast biopsies; and number of first-degree relatives (mother or sisters) with breast cancer.
This information was combined with nationwide breast cancer incidence data from NCI's SEER program and with national mortality data. The researchers then validated the new CARE model using information from 14,059 African American women enrolled in the Women's Health Initiative. The CARE model predicted that 323 women in the group would develop invasive breast cancer. The actual number who developed cancer - 350 - was not statistically different, though the CARE model did underestimate risk among women with a previous benign breast biopsy.
Overall, the CARE model "tended to produce larger estimates of absolute invasive breast cancer risk than the NCI Breast Cancer Risk Assessment Tool in African American women aged 45 years or older," state the authors.
To see how this increased estimation of risk would affect enrollment into breast cancer prevention clinical trials, the investigators compared how many African American women would have been eligible to enroll in the STAR trial using the CARE model versus the number actually enrolled using the NCI Breast Cancer Risk Assessment Tool. Enrollment in the STAR trial required a 5-year projected risk of at least 1.66 percent.
They found that while 14.5 percent of African American women screened using the NCI tool were eligible, this number rose to 30.3 percent using the CARE model. "While the average increase in 5-year risk found with the CARE model compared to the NCI tool is less than one-half percent, the proportion eligible increased by more than twofold," said Dr. Joseph Costantino, director of the National Surgical Adjuvant Breast and Bowel Project Biostatistical Center and co-author of the CARE model.
Like the NCI tool, the CARE model would not be accurate in certain subpopulations, such as women with a prior history of breast cancer or with mutations in genes such as BRCA1 or BRCA2, which greatly increase the risk of breast cancer.
But while the CARE model would still benefit from further validation, especially in women under the age of 50, the authors recommend that clinicians adopt the CARE model "for counseling African American women and for determining their eligibility for breast cancer prevention trials." The CARE model will be included in a revision of the online NCI tool.
—Sharon Reynolds
Communications and Education: A Critical Part of NCI's Mission
NCI has always placed a considerable premium on communication and education - a philosophy that grew in prominence following the passage of the National Cancer Act, which directed NCI to develop methods for ensuring important research findings were disseminated to researchers and to the public.
By reaching out to the public, researchers, policy makers, nonprofit organizations, and advocates, NCI can have a more robust conversation about our priorities, accomplishments, and challenges. We do it through state-of-the-science symposia, our award-winning Web site, the NCI Cancer Information Service, numerous publications, advocacy teleconferences, science writers' seminars, and much more.
But we also recognize two things. First, that as technologies and therapeutic options become more complex, we need to develop new communications and educational tools for translating research findings into venues where they might help improve cancer outcomes. Second, particularly in the current fiscal environment, we must more efficiently and effectively take advantage of the expertise and experience we have within and outside the institute.
As a result, earlier this year two NCI offices, the Office of Communications and the Office of Education and Special Initiatives (OESI), were merged into the new NCI Office of Communications and Education (OCE). And it's my privilege to announce that I have named Lenora Johnson as the new OCE director.
Lenora has served as acting OCE director since the office's formation, and previously was OESI director. Before joining NCI in 2002, Lenora was the program director for the Directors of Health Promotion and Education. There she led numerous initiatives focused on reducing health disparities, global surveillance of health risk behaviors, and capacity building for health promotion and public health education. Organizations such as the Lombardi Comprehensive Cancer Center, the American Public Health Association, Kaiser Permanente, and many community-based organizations have implemented programs Lenora helped develop.
Working closely with senior NCI leadership, Lenora and her staff have done an incredible job of shepherding this new office through a significant reorganization - an action that should have profound benefits for NCI and our key stakeholders.
When completed, this reorganization will ensure that OCE staff are more closely plugged in to the scientific work going on across NCI's divisions and centers, a significant challenge in an organization with approximately 4,000 full- and part-time staff, many of whom are conducting research or managing large research portfolios.
The reorganization has been informed by a complete systems review of how OCE departments conduct their business, consultations with experts to develop more efficient management systems, surveys of external stakeholders, and meetings with national leaders in health communications and education.
OCE's management approach will reflect teamwork and cross-functionality, streamlining work and eliminating redundancies by implementing knowledge management systems and using evidence-based techniques for developing and disseminating materials, as well as optimizing our existing information delivery channels.
These efforts will improve NCI's ability to work with outside partners, allowing for more coordinated efforts in critical areas such as enhancing clinical trial recruitment, addressing survivorship and disparities issues, improving cancer services at the community level, and ensuring that all patients, regardless of their language or literacy, have information that they can understand and use to meet their cancer information needs.
With these changes, senior NCI leadership is confident that we can enhance what are already formidable communication and education programs and activities to better support the efforts of the entire institute.
Dr. John E. Niederhuber
Study Reveals Why Obese Men Have Lower PSA Readings
North American researchers conducting a retrospective multi-institution study have found what they consider the likely explanation for two anomalies: (1) the common observation that men with a higher body mass index (BMI) tend to have lower prostate specific antigen (PSA) readings; and (2) recent results linking obesity with more aggressive prostate disease.
New results conclude that the critical factor is "hemodilution " - a phenomena where the greater volume of blood in bigger men lowers PSA readings by diluting the concentration of the PSA protein, which is believed to enter the bloodstream when the prostate enlarges. Though the findings need to be confirmed in prospective studies, the researchers believe that hemodilution could also compromise evaluation of other circulating disease markers in high-BMI patients.
More than 13,600 patients had radical prostatectomies at Duke Prostate Center, Johns Hopkins Hospital, or 5 Veterans Administration medical centers between 1988 and 2006. All had reliable measurements taken of their BMI and PSA. Using statistical methods, researchers were able to calculate how much blood each patient had, how much actual PSA protein (mass) was present, and thus the PSA concentration. Men with a BMI over 35 (30 and above is obese) had 21-23 percent more blood and 11-21 percent lower PSA concentrations than men of normal weight, without, in most cases, statistically significant increases in the mass of circulating PSA protein.
The work was published in the November 21 Journal of the American Medical Association by Dr. Stephen Freedland of Duke University Medical Center and colleagues from more than a dozen participating centers and institutions. "For these other tests [looking for biomarkers of cancer and other diseases] just starting down the pipeline, " he says, "we need to think of the total amount of a biological marker rather than concentration."
Lung Cancer Patients Report Chemo Side Effects Online
Researchers at Memorial Sloan-Kettering Cancer Center have tested a Web-based system that allows cancer patients to report chemotherapy side effects to their clinicians in real time. The results appear in the December 1 Journal of Clinical Oncology.
During a median 42-week period, 107 English-speaking patients, most of whom were over age 50, were able to use an online platform called Symptom Tracking and Reporting to log and grade physical, mental, and quality-of-life side effects while undergoing treatment for thoracic cancer, predominantly metastatic non-small-cell lung cancer. Patients typically entered their information at computer kiosks in the waiting area of their treatment clinic, though some used a home computer. Clinicians received these reports soon after and were free to follow up according to their judgment.
Patients adhered to the protocol fairly well throughout the study, regardless of age, sex, or disease severity. The only factor tied to adherence was previous experience with computers. Most often, reported barriers to using the system were insufficient time and not being reminded to use it. Nearly all of the patients said they found the system easy to use, wished to continue using it, and would recommend it to others.
If patients receive reminders and validation that the information they submit is truly useful to clinicians, then self-reporting programs such as these may improve efficiency in both clinical research and routine care settings by encouraging patients to follow their treatment regimens, improving the accuracy of toxicity data collection, expediting patient management, and decreasing avoidable hospitalizations, note the authors. The tradeoff, however, is that "between-visit reporting may increase work-burden by generating information that must be reviewed or acted upon."
Elasticity of Cells Could Be a Marker for Cancer
Cancer cells tend to be much softer, or more elastic, than normal cells, and measuring this characteristic on the nanometer scale could be another way to diagnose cancer. Dr. James Gimzewski of the California NanoSystems Institute, collaborating with Dr. Jian Yu Rao of UCLA' Jonsson Comprehensive Cancer Center, profiled the elasticity of live metastatic cancer cells and normal cells from patients' body fluids using atomic force microscopy. The researchers could distinguish between normal and cancerous cells based on their physical characteristics, according to findings published online December 2 in Nature Nanotechnology.
"Measuring the physical features of cancer cells adds another dimension to the analysis of these cells and could help us diagnose the disease, " says Dr. Rao. Unlike normal cells, cancer cells are more flexible and can move through holes and spaces easily, which is how they enter the bloodstream and spread to other organs, according to Dr. Rao. "This is a major reason cancer is so deadly, " he adds.
The researchers tested fluids from patients with suspected metastatic lung, breast, or pancreatic cancer. Each patient sample contained both normal and cancerous cells, allowing the researchers to directly compare the physical characteristics of the cells. The cancerous cells were found to be more than 70 percent softer than the benign cells, based on measurements of cell stiffness at the nanometer scale. The cancerous cells showed a similar physical signature that was distinct from normal cells, even though the patients had different tumor types.
Intensive Quitline Counseling, Free NRT Help More Quit Smoking
The largest randomized trial of its kind has shown that offering more intensive tobacco quitline services, including longer phone counseling sessions and free nicotine replacement therapy (NRT), is a highly effective - and cost-effective - way to help smokers quit.
Published in a special supplement on quitlines in the December 2007 Tobacco Control and partially funded by NCI's Tobacco Research Initiative for State and Community Interventions, the trial was led by researchers from the Kaiser Permanente Center for Health Research in Portland, Oregon.
The trial included 4,600 smokers who called the Oregon tobacco quitline. Callers were randomly assigned to receive one of six types of services: three different types of phone counseling approaches (brief, moderate, or intensive), each with or without free NRT. The most effective approach was the intensive counseling plus free NRT, which helped more than 21 percent of the smokers quit. In comparison, less than 12 percent of smokers quit in the brief counseling with no free NRT arm. The research team defined quitting as no use of any form of tobacco for at least 30 days at the 12-month follow-up.
Callers' satisfaction with the quitline services were far higher in the intensive counseling/NRT arm compared with the brief counseling/no NRT arm (92.5 percent vs. 53.9 percent), although the cost per participant was nearly four times higher, $268 vs. $67, respectively.
"However, our results suggest that higher quit rates, greater client satisfaction, and the potential to attract more smokers to quitlines more than offset the modest additional costs, " said the study' lead author, Dr. Jack Hollis. "Heavily addicted smokers, who have the highest health care costs over time, may benefit even more from intensive counseling and medication."
FDA Approves Liver Cancer Drug; Cautions on Smoking Cessation Agent
The U.S. Food and Drug Administration (FDA) recently approved sorafenib (Nexavar) for use in patients with inoperable hepatocellular carcinoma.
Sorafenib was originally approved in 2005 for the treatment of patients with advanced renal cell carcinoma, a form of kidney cancer. A kinase inhibitor, it interferes with molecules thought to be involved in chemical messages sent within cancer cells, in the formation of blood vessels that supply tumors, and in cell death.
In a separate action, FDA recently issued an Early Communication about its ongoing safety review of varenicline (Chantix), a drug approved as an aid to smoking cessation treatment.
After receiving a case report citing erratic behavior in an individual who had used varenicline, FDA has asked Pfizer, the manufacturer, for any information on additional cases of suicidal ideation in patients who have taken the drug. A safety analysis is under way. In the meantime, FDA recommends that health care providers monitor patients taking varenicline for behavior and mood changes.
Moving Forward in Pancreatic Cancer
Experts on pancreatic cancer met last week to exchange ideas about how to make progress against this deadly disease. Much of the discussion focused on how to identify the most promising potential therapies and test them efficiently in the clinic. Many participants said that combinations of targeted therapies may prove effective against the disease, even though few patients have benefited from the targeted drugs tested to date.
More than 90 researchers, clinicians, patient advocates, and pharmaceutical industry representatives discussed topics ranging from mouse models and cancer stem cells to the pitfalls of designing and interpreting clinical trials. The meeting was organized by the NCI Gastrointestinal Cancer Steering Committee and was the first in a series of state-of-the-science conferences sponsored by NCI's Coordinating Center for Clinical Trials.
"We are facing a bit of a crisis in pancreatic cancer clinical research," said Dr. Margaret Tempero of the University of California, San Francisco. "We seem to make progress in identifying potential therapies in isolated institutional clinical trials, yet when we test these agents in a broader population, they fail."
Failure may occur for several reasons, and they are not always clear. Patients in early-stage trials could be less sick than patients in the broader population and therefore fare better, for instance.
Many participants said that a single drug is unlikely to be effective against this genetically complex disease. Pancreatic tumors are notorious for resisting the antitumor effects of targeted drugs by activating alternative pathways.
Some of the molecules involved in transmitting cancer-promoting messages have been identified, but the most important players in these complex networks are not known. "The essential problem with pancreatic cancer is that we're trying to make progress in the face of biological uncertainties," said Dr. James Abbruzzese of University of Texas M.D. Anderson Cancer Center.
A recent study suggesting that multitargeted therapies may be required to treat glioblastoma brain cancer could apply to pancreatic cancer, said Dr. Abbruzzese. Both cancers are genetically and clinically diverse and resistant to therapies.
Pancreatic cancer is the fourth most deadly cancer in the U.S., though it is not among the 10 most common. The cancer is frequently diagnosed only after it has spread beyond the pancreas, and treatment options are limited. Surgery is the best hope for a cure among some patients with cancer localized to the pancreas.
The primary chemotherapy drug used to treat pancreatic cancer, gemcitabine (Gemzar), helps a minority of patients. With the exception of erlotinib (Tarceva), few of the targeted drugs tested to date have shown a benefit for patients.
Still, critical genes have been identified, and there was reason for optimism at the meeting. Mouse models have generated interest because the mice, like their human counterparts, develop tumors that spread easily and resist most treatments. In addition, recent studies suggest that some patients may benefit from adjuvant therapies following surgery.
"We have much more knowledge about the basic science of pancreatic cancer today than we did several years ago," said Dr. Philip A. Philip of Karmanos Cancer Center, Wayne State University. "We also have inventories of targeted drugs that we could use if only we can figure out how to test these drugs in patients in ways that provide us with informative results."
The group plans to report its findings and recommendations in 2008. In the meantime, there was a consensus to do more pilot clinical trials with smaller numbers of patients before embarking on large randomized trials, said Dr. Philip. This would ensure that the most promising treatments are taken to final-stage trials with a much better chance of success.
The need to develop experimental tools such as mouse models was also stressed. "There was general agreement on the importance of these tools in helping us to design trials and in choosing drugs and selecting patients to get the maximum benefit," said Dr. Philip.
—Edward R. Winstead
Immune System Fights Cancer to a Draw
Researchers have shown in mice that the immune system can restrain the growth of cancer cells for extended periods, preventing dormant cancers from developing into life-threatening tumors. The findings raise the possibility that a new class of immune therapies could be developed to control rather than eliminate cancer cells.
Using the human immune system to keep dormant tumors in check may be a worthy goal of immune therapies, says Dr. Robert Schreiber of the Washington University School of Medicine, who co-led the study with Dr. Mark Smyth at the Peter MacCallum Cancer Centre in Victoria, Australia.
The immune system is often described as a double-edged sword for cancer because it appears to both prevent and promote the disease. For instance, acute inflammation may induce antitumor immunity that may eradicate cancer cells, while chronic inflammation may set the stage for cancer. The new results, published online in Nature last month, point to another role: maintaining tumors in a state of dormancy, or equilibrium.
"We hope that this work will open up a new appreciation of the many ways the immune system controls cancer," says Dr. Schreiber. The experiments were done in separate labs using different types of mice, but the results were the same. If they are generalizable to other tumors and extended to humans, the findings may help explain clinical observations about cancer, such as why the disease tends to occur late in life.
"It's possible that part of the reason the disease takes so long to develop is that tumors get held in an equilibrium state for a substantial period of time," notes Dr. Schreiber.
The findings lend support to recent studies showing that the presence or absence of certain immune cells in ovarian and colorectal tumors may predict the survival of patients with these diseases. The results may also shed light on why cancer cells are present in individuals who have no clinical signs of disease, such as some men with prostate cancer.
The findings could also help explain reports of melanoma skin cancer being transferred through organ transplantation. A letter to the New England Journal of Medicine in 2003 reported that two patients developed melanoma after each received a kidney from the same donor. The donor had been treated for melanoma 16 years earlier and was considered free of cancer, an investigation revealed. Evidently, the donor's melanoma had been under immune control for those years, but was awakened in the recipients, whose immune systems were suppressed to prevent organ rejection.
Dr. Schreiber and his colleagues are now studying the molecular basis of equilibrium. With the isolation of dormant tumors for the first time, researchers will be able to compare the genetic signatures of these lesions with those of lesions that became cancerous even in individuals with competent immune systems.
To isolate the dormant tumors, the researchers injected mice with low doses of methylcholanthrene, a carcinogen. A fifth of the mice developed fatal tumors. The surviving animals appeared healthy, but about half were found to have nodules near the injection sites that contained a mixture of tumors cells and immune cells. These were dormant tumors.
The tumors were held in a dormant state by the adaptive immune system, which involves immune cells such as T cells, the researchers found. When they blocked the critical immune cells, the tumors started to grow almost immediately.
"This study is the next step in our understanding of how the immune system interacts with cancer and influences the outcome of cancer," says co-author Dr. Lloyd Old of the Ludwig Institute for Cancer Research. "The challenge now is to understand the mechanisms that allow the immune system and the cancer to come to a state of dormancy, or equilibrium."
In theory, finding ways to augment a person's adaptive immune system could increase control over cancer. "We may be able to induce a chronic state of equilibrium that would render cancer into more of a controllable disease such as diabetes," Dr. Schreiber says. "If we currently cannot use the immune system to cure cancer, maybe we can use it to control the disease."
—Edward R. Winstead
Groups Issue Report on Diet, Weight, Exercise, and Cancer Risk
Maintain a healthy body weight. Fill your plate with vegetables and fruit and say no to sugary soft drinks. Get off the couch and take a walk. Public health advocates have long promoted such healthy lifestyle recommendations to prevent chronic conditions such as diabetes and heart disease. Now a report by the American Institute for Cancer Research and the World Cancer Research Fund, Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective, concludes that following the same advice is likely to significantly reduce cancer risk as well.
The report - a comprehensive review of the scientific evidence linking cancer to diet, physical activity, and weight - finds convincing evidence that obesity is a cause of colorectal, endometrial, esophageal, kidney, liver, pancreatic, and postmenopausal breast cancer; that abdominal obesity, in particular, causes colorectal cancer; and that consumption of red and processed meat such as bacon, ham, pastrami, and salami, also causes colorectal cancer.
Its recommendations for reducing cancer risk include avoiding weight gain and increases in waist size, getting at least 30 minutes of physical activity every day, limiting red meat consumption to 18 oz. of cooked meat per week (about 2.5 oz. per day), and eating very little, if any, processed meat.
"This is the largest, most systematic review of the role of diet in cancer prevention that has been conducted to date," says Dr. Arthur Schatzkin of NCI's Division of Cancer Epidemiology and Genetics, a member of the international expert panel that distilled the evidence and formulated the recommendations.
Five years in the making, the report is the outcome of a process that involved 9 teams of scientists from around the world, who evaluated more than 7,000 studies on diet, physical activity, weight management, and cancer.
Among the report's conclusions is that cancer risk increases by 15 percent for every 1.7 oz. of red meat consumed per day beyond the recommended limit of 18 oz. per week. Dr. Schatzkin notes that, for an individual, this is a relatively modest increase in risk. By contrast, a person who smokes two packs of cigarettes a day may increase their cancer risk by as much as 2,000 percent compared with that of a nonsmoker.
"At the population level, however, these apparently modest risks have substantial health effects," Dr. Schatzkin explains. "Because many people eat red and processed meat and many are obese, the burden of cancer attributable to these nutritional factors may be substantial. If we could reduce the incidence of, say, breast cancer or colorectal cancer by 15 percent, that would mean preventing a significant amount of disease and death."
The report finds convincing evidence that having children and breastfeeding them reduces a woman's lifetime risk of developing breast cancer. Additionally, breastfed infants may have a lower risk of becoming obese and thus a reduced risk of cancer. It recommends that infants be exclusively breastfed for up to 6 months.
Dr. John Milner of NCI's Division of Cancer Prevention was an observer on the expert panel and chair of a working group that evaluated the scientific evidence for mechanisms by which dietary components may cause cancer. He notes that individual susceptibility to cancer from dietary causes varies widely because of genetic and other factors, but researchers don't yet know enough to craft dietary recommendations based on individual risk levels.
The report's dietary recommendations are consistent with current scientific knowledge and with dietary guidance promoted by the U.S. government through the Dietary Guidelines for Americans, the "Fruit and Veggies - More Matters" campaign (formerly "5 A Day for Better Health"), and other programs, Dr. Milner says.
The report recommends against consumption of dietary supplements to prevent cancer. Although some studies, usually in high-risk groups, have suggested that supplements can reduce cancer risk, these findings may not apply to the general population. The panel concludes that "the best source of nourishment is food and drinks."
—Eleanor Mayfield
New Drug Combination for Ovarian and Primary Peritoneal Cancers
Name of the Trial
Principal Investigator
Why This Trial Is Important
Systemic chemotherapy with a platinum-containing drug, such as cisplatin or carboplatin, is a commonly used treatment for advanced ovarian epithelial cancer. Although this type of treatment frequently results in tumor shrinkage, most patients ultimately become resistant to platinum-based chemotherapy.
In this trial, women with ovarian epithelial or primary peritoneal cancer whose disease has relapsed less than 6 months after treatment with initial chemotherapy will receive cisplatin and a drug called flavopiridol. Flavopiridol blocks the activity of a number of proteins that help cancer cells grow and spread, and it may also make cancer cells more sensitive to cisplatin.
"Women with platinum-resistant ovarian cancer have very few effective treatment options," said Dr. Bible. "Our laboratory studies have shown that flavopiridol can increase the platinum concentrations in cells when administered with cisplatin, and we believe that this may lead to a reversal of platinum resistance.""An early analysis of patients currently on the trial has revealed a better than expected response rate, including one patient with a complete remission," he added.
Who Can Join This Trial
Study Site and Contact Information
An archive of "Featured Clinical Trial" columns is available at http://cancer.gov/clinicaltrials/ft-all-featured-trials.
Following are newly released NCI research funding opportunities:
Pilot-Scale Libraries for High-Throughput Screening
Letter of Intent Receipt Dates: Dec. 12, 2007; Dec. 12, 2008.
This funding opportunity will use the P41 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3804. Inquiries: Dr. John M. Schwab - email@example.com.
New Methodologies for Natural Products Chemistry
Letter of Intent Receipt Date: Dec. 23, 2007.
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3805. Inquiries: Dr. John M. Schwab - firstname.lastname@example.com.
Discovery of Novel Epigenetic Marks in Mammalian Cells
Letter of Intent Receipt Date: Jan. 14, 2008.
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3802. Inquiries: Dr. Philip F. Smith - email@example.com.
Technology Development in Epigenetics
Letter of Intent Receipt Date: Jan. 14, 2008.
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3799. Inquiries: Dr. John Satterlee - email@example.com; Dr. David M. Balshaw - email@example.com.
Studies of the Ethical, Legal, and Social Implications of Human Microbiome Research
Letter of Intent Receipt Date: Jan. 15, 2008.
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3806. Inquiries: Dr. Jean E. McEwen - email@example.com.
Limited Competition: AIDS and Cancer Specimen Resource
Application Receipt Date: Jan. 15, 2008.
This is a renewal of RFA-CA-02-001 and will use the U01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3798. Inquiries: Dr. Rebecca Liddell Huppi - email@example.com.
Support of Competitive Research Advancement Award
Application Receipt Dates: Non-AIDS Applications (new, renewal, resubmission, or revision): Jan. 25, May 25, Sept. 25, 2008; Jan. 25, May 25, Sept. 25, 2009; Jan. 25, May 25, Sept. 25, 2010; Jan. 25 and May 25, 2011.
This is a renewal of PAR-06-491 and will use the SC1 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3795. Inquiries: Dr. Hinda Zlotnik - firstname.lastname@example.com.
Support of Competitive Research Pilot Project Award
Application Receipt Dates: Non-AIDS Applications (new, renewal, resubmission, or revision): Jan. 25, May 25, Sept. 25, 2008; Jan. 25, May 25, Sept. 25, 2009; Jan. 25, May 25, Sept. 25, 2010; Jan. 25 and May 25, 2011.
This is a renewal of PAR-06-492 and will use the SC2 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3796. Inquiries: Dr. Hinda Zlotnik - email@example.com.
Support of Competitive Research Research Continuance Award
Application Receipt Dates: Non-AIDS Applications (new, renewal, resubmission, or revision): Jan. 25, May 25, Sept. 25, 2008; Jan. 25, May 25, Sept. 25, 2009; Jan. 25, May 25, Sept. 25, 2010; Jan. 25 and May 25, 2011.
This is a renewal of PAR-06-493 and will use the SC3 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3797. Inquiries: Dr. Hinda Zlotnik - firstname.lastname@example.com.
Exfoliated Cells, Bioactive Food Components, and Cancer
Application Receipt Dates: Non-AIDS Applications (new): Feb. 5, June 5, and Oct. 5, 2008; Feb. 5, June 5, and Oct. 5, 2009; Feb. 5, June 5, and Oct. 5, 2010.
This is a renewal of PA-07-207 and will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3807. Inquiries: Dr. Cindy D. Davis - email@example.com; Dr. Britt C. Reid - email@example.com.
Molecular Approaches to Diet and Pancreatic Cancer Prevention
Application Receipt Dates: Non-AIDS Applications (new): Feb. 5, June 5, and Oct. 5, 2008; Feb. 5, June 5, and Oct. 5, 2009; Feb. 5, June 5, and Oct. 5, 2010.
This is a renewal of PA-07-257 and will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3809. Inquiries: Dr. Sharon Ross - firstname.lastname@example.com.
Reference Epigenome Mapping Centers
Letter of Intent Receipt Date: Feb. 7, 2008.
This funding opportunity will use the U01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3800. Inquiries: Dr. Frederick L. Tyson - email@example.com; Dr. Christine M. Colvis - firstname.lastname@example.com.
Epigenomics Data Analysis and Coordination Center
Letter of Intent Receipt Date: Feb. 7, 2008.
This funding opportunity will use the U01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3801. Inquiries: Dr. Joni Rutter - email@example.com; Dr. Kim McAllister - email@example.com.
Exfoliated Cells, Bioactive Food Components, and Cancer
Application Receipt Dates: Non-AIDS Applications (new): Feb. 16, June 16, and Oct. 16, 2008; Feb. 16, June 16, and Oct. 16, 2009; Feb. 16, June 16, and Oct. 16, 2010.
This is a renewal of PA-06-359 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3808. Inquiries: Dr. Cindy D. Davis - email@example.com; Dr. Britt C. Reid - firstname.lastname@example.com.
Quick-Trials for Novel Cancer Therapies and Prevention: Exploratory Grants
Application Receipt Dates: March 7, July 9, and Nov. 7, 2008; March 9, July 9, and Nov. 9, 2009; March 9, July 9, and Nov. 9, 2010.
This is a renewal of PAR-06-451 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3794. Inquiries: Dr. Heng Xie - email@example.com; Dr. Bhadrasain Vikram - email@example.com.
If Memory Serves...
NIH had two personnel systems when NCI was created: the Commissioned Corps of the Public Health Service and the Federal Civil Service. (Read more)
For more information about the birth of NCI, go to http://www.cancer.gov/
Dr. Ernest T. Hawk, director of NCI's Office of Centers, Training and Resources (OCTR), has been named vice president and division head for Cancer Prevention and Population Sciences at the University of Texas M.D. Anderson Cancer Center in Houston. Dr. Hawk joined NCI's Division of Cancer Prevention (DCP) in 1993.
Since 2004, Dr. Hawk has served as director of OCTR. Prior to this, he was chief of the Gastrointestinal and Other Cancers Research Group in DCP. Dr. Hawk's work in the area of nonsteroidal anti-inflammatory drugs for cancer prevention was recognized with the NCI Research Award for Distinguished Achievement in Cancer Prevention.
Dr. Hawk also co-chaired NCI's Translational Research Working Group, which drafted a plan approved by the NCAB in June 2007 proposing a series of major initiatives for the NCI to consider in the area of translational research.
Dr. Jaye L. Viner has been appointed acting director of OCTR, where she has served as the deputy director since 2006.
Dr. Hiroaki Mitsuya, head of the Experimental Retrovirology Section in the HIV and AIDS Malignancy Branch in NCI's Center for Cancer Research, has been awarded the 2007 Keio Medical Science Prize. The award is presented by the Keio University Medical Science Fund and recognizes major projects that contribute to the advancement of life sciences and medicine and encourage the expansion of researcher networks. Dr. Mitsuya's work is highly regarded as a clinical breakthrough in the treatment of AIDS. He discovered that AZT inhibits HIV activity, and subsequently developed it as the first drug to treat AIDS. He also later developed the drugs ddI and ddC. The drugs have been used in clinics around the world and have dramatically improved the prognosis of HIV-infected individuals.
Teleconference Focuses on Cancer Survivorship Research
Dr. Julia Rowland, director of NCI's Office of Cancer Survivorship (OCS), will highlight cancer survivorship research and Lourie Campos, a member of the NCI Director's Consumer Liaison Group, will discuss her role in working with OCS to plan the annual cancer survivorship conference. The teleconference can be accessed toll free within the U.S. at 800-857-6584; the passcode is OCS. Toll-free playback will be available through January 11 at 800-253-1052. For more information contact OAR at 301-594-3194 or email@example.com.
NCAB Meeting Held
NCI and AACR Sponsor Meeting on Cancer Health Disparities
Going for the Gold
Earlier this year, the University of Texas M.D. Anderson Cancer Center became the first NCI-designated comprehensive cancer center to be accredited as a Gold Standard employer. I am proud of the effort our employees put forth to help us earn accreditation, and even more pleased by the potential life-saving and life-lengthening impact the Gold Standardcan have on our employees and their families. I also realize the synergy that can be created when cancer centers stand together with business leaders in this effort. That is why I encourage the directors of all NCI-designated cancer centers to embrace this unique opportunity on behalf of their employees and their institutions.
Today, I am delighted to report that under the leadership of Dr. Victor Dzau, Duke Medicine, which includes the Duke University Health System, Comprehensive Cancer Center, School of Medicine, and School of Nursing, recently received Gold Standard accreditation.
At the heart of the Gold Standard are three goals: prevention, early detection, and quality care. At M.D. Anderson, wellness is more than just activities and programming - it is part of our culture. Our 17,000 employees are our most important resource and we take pride in our employee benefits, wellness programs, and work-life balance opportunities that blend to create a "wellness-friendly" culture. The "Place…of wellness" at M.D. Anderson provides complementary services such as yoga, nutrition classes, tai chi, meditation, and aromatherapy to patients, their caregivers, and family members. Our Employee Health & Well-being Department provides programming and activities for employees and their families that build the knowledge, skills, and commitment it takes to be healthy.
As you walk around M.D. Anderson, you immediately feel the wellness culture. Throughout the institution, many of our waiting areas have aquariums that can help reduce stress levels. We have 12 "stress buster" stations with elliptical trainers, stretch trainers, and strength chairs that staff use to re-energize their day. Good nutrition, daily physical activity, and support for tobacco cessation are all core components of the Gold Standard. With more than 10,000 meals served each day, we work to provide nutritious choices for all who come to our campus. The Pyramid Plate program offers a selection of foods that have been found to decrease cancer risks. And our new Healthy Balance vending areas offer fruit, whole grain, low-fat, and low-calorie snack options. M.D. Anderson's campus is growing, and we use the old and new sky bridges linking our major buildings to provide miles of indoor walking opportunities.
The Gold Standard has also helped us remove many of the barriers for our cancer screening programs offered to employees. In January of 2008 we will launch a Health Risk Assessment to help employees better understand their health risk and the steps they can take to be healthy.
I am proud of our CEO Cancer Gold Standard effort and hope that by sharing a little of our story, others will be encouraged to "go for the gold."
Dr. John Mendelsohn


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Balance Ball Chair Cover
Item# 05-59758
Our Balance Ball Chair Cover is the perfect accessory to our 52cm Balance Ball or Balance Ball Chair.
Special Offer: 20% off our Velvety Balance Ball Cover (05-59756_2) with the purchase of our Balance Ball Chair Kit (95-9320) Final discount reflected in cart. (Details)
The faux velvet zipped cover fits seamlessly over the 52cm Balance Ball to provide a new color accent or a smoother, more comfortable feel. Add interest to any decor, or use for light workouts.
Balance Ball Chair Cover Features:
- Faux velvet material is soft to the touch making for a more comfortable sitting experience
- Covers zip on and off for convenience
- Ideal for extra seating or light workouts
- Designed specifically to fit our 52cm Balance Ball
Rated 5 out of 5 by 1 reviewer.
Rated 5 out of 5 by anyalinks a must have I love the color and now I don't stick to the ball when it gets warm in my room. My only complaint is it arrived days after my balance ball chair which meant I had to go through the process of letting the air out and then inflating it---again! Either it should arrive with the ball or if purchased separately then it should have a long enough zipper. June 10, 2014
1-1 of 1
(6 Questions : 6 Answers)
Product Q&A
Ask your questions. Share your answers.
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I had a ball for a long time. Then I got a cat and he jumped on it and punctured it. I want to get another ball, but am trying to figure out how to protect it from the cat. Will this work?
2 months, 1 week ago
Top 10 Contributor
Answer:This Balance Ball Chair Cover is used to provide extra comfort while using your ball. The faux velevet material however, will not protect from punctures.
2 months, 1 week ago
1 answer
Can this fit a 55-cm ball?
I'd like to use it with the custom ball chair.
5 months, 1 week ago
Miami, FL, USA
Top 10 Contributor
Answer:Yes! Our balance ball cover will be able to accommodate the 55cm ball.
5 months ago
1 answer
Where was this product manufactured
I am attempting to only buy things that are NOT manufactured in China. Can you tell what country this was made in, not distributed by, but acutally the manufactuing country?
7 months ago
Chicago, IL
Top 10 Contributor
Answer:This Ball Chair cover is made in China.
6 months ago
9 months ago
Top 10 Contributor
Answer:The Balance Ball Cover is washable on a delicate cold cycle.
9 months ago
1 answer
What is the fabric made of?
Can it fit any 52 cm ball?
9 months ago
Los Altos, CA
Top 10 Contributor
Answer:The fabric for the balance ball chair cover is made of faux velvet. As long as the balance ball is 52cm, the cover will fit!
9 months ago


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|0. PostgreSQL Multiple Precision Arithmetic - This extension adds support in PostgreSQL for the data types and
functions avaliable in the GMP library for arbitrary precision
|Activity Percentile: 68.25
Activity Ranking: 41.00
Registered: 2011-03-09 10:46
|1. BioPostgres - BioPostgres is a collection of modules that extend PostgreSQL for Computational Biology. It implements new datatypes (graph, range, location, etc) with query operators, index and related tools for large-scale analysis. See also http://biopostgres.org
|Activity Percentile: 42.86
Activity Ranking: 73.00
Registered: 2006-01-09 01:55
|2. PostBio - PostBio is a set of bioinformatics extensions for PostgreSQL including specialized data types and routines.
|Activity Percentile: 39.68
Activity Ranking: 77.00
Registered: 2008-01-09 21:12
|3. PostStat - PostStat is a set of statistics extensions for PostgreSQL. It includes routines that compute a number of cumulative probability distributions, linear regression, and statistical tests, both parametric and non-parametric.
|Activity Percentile: 18.25
Activity Ranking: 104.00
Registered: 2008-01-15 00:35