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Download the 27 Storm Track Weather App for your chance to win a $500 overnight package from Sundara Inn & Spa or a snow thrower from Ariens. Sign up today through Monday, December 31, 2012 for your chance to win. Two winners will be randomly selected Thursday, January 3; one will receive the overnight package and one will receive the snow thrower.
1. No purchase necessary.
2. Viewers must download the 27 Strom Track Weather App from a smart phone or tablet. Once you are on the weather app site click on the banner inviting you to win an overnight package from Sundara Inn & Spa or an Ariens snow thrower and fill out the form completely. Entries sent in another format will be disqualified. The winner will be chosen by random drawing from the entries received which correctly followed all the directions for entry. Winner will be required to supply the following information to the station: name, current address, current telephone number, email address, age and sex. The accuracy of this information may be verified before the prize is presented to the winner. Only one entry is allowed.
3. Odds of winning are based on the number of entries received.
4. Must be at least 18 years of age to win.
5. WKOW will conduct the sweepstakes and WKOW will be the final judge on all matters related to this sweepstakes. The judges' decisions are final, binding and conclusive on all matters. By entering this sweepstakes, entrants accept and agree to be bound by these rules and the decisions of the judges relative to the sweepstakes. WKOW reserves the right to change the rules at any time
6. In the event of non-compliance, an alternative winner may be selected.
7. Winner's voice, name & likeness may be used for publicity purposes without further compensation. By entering, participants agree to release, discharge and hold harmless WKOW and participating sponsors and their affiliates, advertising and promotion agencies, printing suppliers, and prize suppliers from damages arising out of the acceptance, use, misuse or possession of any prizes received in this sweepstakes.
8. Employees of WKOW and their families, its subsidiaries, divisions and related companies, its promotional agencies and all participating promotional partners are not eligible.
9. Prize value is approximately $500-$1,400. Taxes are the responsibility of the winner. No cash substitutions permitted. Prize is non-transferable.
10. Any taxes are the responsibility of the winner.
11. WKOW reserves the right to settle all disputes and to change and alter the details of the sweepstakes as circumstances merit.
12. WKOW requires the winner to come to the WKOW at 5727 Tokay Blvd, Madison, WI 53719 weekdays between the hours of 8am-5pm to claim their prize. Winners must sign a liability release, publicity release and accept or decline release. Prizes cannot be mailed. Winner may be required to pick up their prize at sponsor location.
13. Winners are not eligible to win another contest or sweepstakes with WKOW for 30 days after winning.
14. WKOW and sponsors reserve the right to terminate this sweepstakes at any time.
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www.pickmaxshoes.com wholesale and retail Cheap Nike Air Max Shoes,Asics Onitsuka Tiger shoes,NFL Jerseys free shipping
pickmaxshoes.com is a professional online shoe shop specializing Nike Air Max shoes with low price and guaranteed quality. Our main produts are: Nike Air Max Shoes,Air Max 90,Air max 95, air max 2009,Air max 2011,Air max 24-7,air max 87,air max TN,BW,air max 2010,air max zenyth,air max skyline, air max structure triax 91,air maxtrainer 1+low,air max Taiwind 2009,air max 180,Air Max Griffey 2011,Air Pegasus 89, Air Waffle Trainer,Air Max Terra Ninety,2012 shoes. asics onitsuka tiger shoes, Asics Mexico 66,Asics MINI,NFL Jerseys ......They are very popular and sell well online with reasonable price, high quality and best service. Welcome to www.pickmaxshoes.com and get more details about more products. Nike shoes are chosen by many people all the time. If you also love Nike Shoes, http://www.pickmaxshoes.com is a good choice. If you have any question,Please contact email@example.com Free Shipping Paypal payment wholesale and retail. Web site: http://www.pickmaxshoes.com

subset: commoncrawl


text:
Ginkgo Biloba Treatment Fenton MO
Medical School: Univ Of Mo-Kansas City Sch Of Med, Kansas City Mo 64108
Graduation Year: 1994
Medical School: Med Coll, Guru Nanak Dev Univ, Amritsar, Punjab, India
Graduation Year: 1952
Saint Louis, MO
Neurological Surgery
Medical School: Univ Of Mo, Columbia Sch Of Med, Columbia Mo 65212
Graduation Year: 1966
Hospital: St Anthonys Med Ctr, Saint Louis, Mo
Group Practice: Signature Health Svc
Saint Louis, MO
Medical School: Med Coll Of Ga Sch Of Med
Year of Graduation: 1992
General Information
Accepting New Patients: Yes
RateMD Rating
5.0, out of 5 based on 1, reviews.
Saint Louis, MO
Medical School: Univ Of Ok Coll Of Med, Oklahoma City Ok 73190
Graduation Year: 1999
Saint Louis, MO
Saint Louis, MO
Medical School: Univ Of Ne Coll Of Med, Omaha Ne 68198
Graduation Year: 1981
Saint Louis, MO
Saint Louis, MO
Medical School: Univ Wien, Med Fak, Wien
Year of Graduation: 1978
General Information
Hospital: Des Peres, Saint Louis, Mo
Accepting New Patients: Yes
RateMD Rating
3.6, out of 5 based on 7, reviews.
8 Ways to Feed Your Brain
It really is all in your head—all three pounds and 100 billion neurons of it, that super biocomputer affectionately known as the brain. And now that Americans live, on average, for 78 years (three decades longer than they did in 1900), it doesn't take, well, a brain surgeon to figure out that nurturing the brain's health makes perfect sense.
Studies clearly illustrate how lifestyle choices can directly impact the brain's physiological well-being. Mental stimulation, loving companionship, social interaction, regular exercise, and a healthy diet undoubtedly benefit the brain—and the individual as a whole. Of course, our genes have their own fateful designs, and Father Time ultimately takes his toll—with Alzheimer's, Parkinson's, multiple sclerosis, stroke, or depression as the potential fee. Fortunately, a growing body of research suggests that certain natural substances may help protect the brain during aging, along with possibly enhancing its function in the short and long terms. Here are 10 to consider. Ginkgo biloba. Almost universally accepted as an effective treatment for deteriorating memory and early-stage Alzheimer's disease, this age-old herb boasts high levels of antioxidants and enhances blood flow in the brain.
1. Omega-3 fatty acids
Used to manufacture and maintain cell membranes, omega-3s act as anti-inflammatories and mildly thin the blood. Omega-3s come in three major types: Alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). Omega-3s, especially DHA and EPA, may augment brain function by fortifying the myelin sheath, a fatty membrane that covers and insulates each nerve cell. They might also help the blood deliver nutrients directly into neurons. Results from a Harvard Medical School-McLean Hospital study found that DHA/EPA supplements significantly reduced depression and mania in bipolar-disorder patients. Dosage: 200 mg to 2 grams/day.
2. Coenzyme Q10 (CoQ10)
CoQ10 activates specific enzymes in the "powerhouses" of cells, the mitochondria, to produce adenosine triphosphate (ATP), the cells' primary energy source. Then, in its role as an antioxidant, it helps neutralize the free radicals that get created during ATP production. Scientists from University of California, San Diego School of Medicine demonstrated that Parkinson's patients had lower levels of CoQ10 than healthy controls, possibly indicating diminished ATP production in the patients' brains. The research also showed that CoQ10 supplements actually slowed the functional decline of early-stage Parkinson's. Dosage: 30 mg to 200 mg/day.
Acetyl-L-Carnitine (ALC)
Acetyl-L-carnitine (ALC helps deliver long-chain fatty acids into the nerve cells' mitochondria for ATP production and acts as a potent antioxidant. Recent research suggests that levels of ALC decrease with age, which may lead to decreased ATP production and free-radical stress in neurons, potential factors in the loss of mental acuity or age-related demen...
Copyright 1999-2009 Natural Solutions: Vibrant Health, Balanced Living/Alternative Medicine/InnoVisi...


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Real news. Real funny.
Real news. Real funny.
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text:
There's never a lack of news in this town. And to prove it, here is your week in review.
A Wayne County judge on Monday said there was no shame in his game. Then his naked shower scene photograph went viral. By Friday, Circuit Court Judge Wade McCree said in fact there was shame in his game and issued an apology to everybody but the woman he sent it to.
Detroit Mayor Dave Bing remained AWOL. We're told he has be recuperating from colon surgery for more than a month now. First we were told it was dental discomfort. People begin to wonder if there is some "Weekend at Bernie's" conspiracy being perpetrated here.
There were the usual Detroit Police boners – squad cars being held hostage, a gunman escaping from a police van with the help of a handcuff skeleton key kept in his underwear , news that women were not warned about a serial rapist until he allegedly raped and shot a third woman in front of her baby. Suffice it to say the department is in need of an overhaul.
But what about Bob?
Beleaguered Wayne County Executive Bob Ficano remains under the magnifying glass of the FBI. Hoping that the Feds can pin nothing on him, Bob continues to try and push the boulder up the mountain and remake his image as a credible leader.
It's not working. President Obama dissed Bob when he came to Wayne County last week and wouldn't let him in the door.
Bob recently showed up to a local politician's fundraiser. I'm told everyone there was trying to avoid a photograph with Bob.
Once the most prodigious fundraiser in Michigan politics, Bob's PAC raised zilch last quarter, according to filings released this week.
If the old saying is true – that money is the lifeblood of a politician – then there's no other way to say it. Bob's a corpse.
205 N. Michigan Avenue
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text:
Officials in Stevens County continue to investigate a terrible case of animal abuse at a home in Ford. A rescue operation took place after deputies and a social services case worker found more than a dozen dead dogs and 34 abandoned dogs on a property off of Highway 291. The dogs are currently staying at the Spokane Humane Society as employees there work to get them to better health. In the coming weeks the dogs will be available for adoption.
Bill Sheppard lives right across the street from the abandoned property. He said two older women, who no longer live there, recently moved out after they stayed without heat, power and electricity for five years.
Ken Holm was one of ten volunteers who helped rescue the animals over the weekend. He said that they had to physically pry the dead dogs from the ground because they had frozen over the winter.
The two women who used to live there stayed most recently in an 8x10 blue shed, but now relocated to an assisted living home in Spokane.
All content © Copyright 2000 - 2014 WorldNow and KHQ. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms of Service.


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Yep it's true and this is gonna be a tell all movie so all the juicy secrets will be revealed. None of the original cast is involved. Lifetime will be airing this movie on September 1st. I will definitely have my DVR rolling for this considering I can quote just about every line to every episode. What can I say i'm a FAN.
Will you be watching?


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In one of the most bizarre lawsuits you will ever see, a Little League coach is suing a 14-year-old player over his game winning celebration.
Coach Alan Beck says he was seriously injured when a player tossed his helmet in the air as he crossed home plate to score the game winning run last April. The helmet struck the coach in the lower leg, tearing his Achilles tendon. Now the coach is asking for $500,000 from the boys family. The boys father thought it was a joke and so did I but this is real. Check out an interview with the coach here!
So does the former coach have a case?


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There was a solemn ceremony on Friday for a reserve police officer hit and killed as he rode his motorcycle.A procession paused at 21 Mile and Jefferson, the very place where Officer Patrick Wisniewski was killed on Sunday. There were a lot of tears as his wife and children placed flowers at the site beneath a wreath and his picture.Wisniewski was a reserve officer for New Baltimore, but he was a hero wearing a different hat as an airman at Selfridge Air National Guard Base."My husband would leave for the day, and he would go do his military duties, and then he would come home and within an hour change uniforms, put on the New Baltimore uniform, and leave again to serve the community," said Jennifer Wisniewski.It was that humility and sense of duty that carried him from reserve officer to more. He wanted to serve. He was about to be hired as a full-time officer in New Baltimore."My kids would actually line up at the front door, and they're going, 'Daddy, you're going out to protect us from the bad guys,' and they'd hug and kiss him," Wisniewski said. "It was high fives all the way out the door with them lined up, and they knew that they were safe.""You have someone out, suspended license, operating while intoxicated. It's a tragedy, and it is a severe loss, not only to this community and nation, but to these children, these young kids that he has," said New Baltimore Police Chief Tim Wiley.The driver accused of hitting Wisnewski is facing charges.The hardest thing now is what Jennifer Wisnewski has had to teach her children, a lesson in loss as she herself tries to cope."They know that daddy is up in heaven. They ask every once in a while if daddy's going to come back down, and I just get them through every day by telling them, 'Close your eyes, baby, and you'll see him. You can talk to him,'" she said.The long procession started in New Baltimore, stretched through Chesterfield Township and ended at the chapel at Selfridge Air National Guard Base where the pain of loss was felt, but equally pride, as well. Family, friends, airmen and police officers all gave a final salute to a humble hero.A memorial mass for Wisnewski is planned for Saturday, and his burial will take place on Monday.
WJBK-TV | Fox 2 16550 West Nine Mile Rd.Southfield, MI 48075Main Station: (248) 557-2000Newsroom: (248) 552-5103


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Major League Baseball should be embarrassed over the turnout at their Hall of Fame induction ceremony last Sunday. Normally, you'll have crowds approaching 20-thousand in Cooperstown. This year, the crowd maybe was close to 25-hundred. Maybe it was because MLB inducted 3 guys who've been dead for 50-years.
Two questions.
One, why did it take 50-years for the dead guys to be inducted?
Two, is the current list of players eligible for the Hall of Fame that bad?
I can give you an answer to #2. The voting for baseball's shrine is flawed and should be changed. You've got a bunch of baseball writers who won't vote for certain players for really dumb reasons, like what their personality was like. Didn't matter what they did on the field, you have voters who will determine someone's fate because they didn't give a newspaper guy an interview.
It's time for MLB to handle their Hall of Fame like the NFL.
The NFL has a 46-member selection committee. It's made up of media representatives from around the country and 13 at-large selections. There job? Discuss and determine who gets in. The selection committee will be polled three times before the final list of nominees is determined . In order to get into the NFL Hall of Fame, players must receive a minimum of 80% of the vote. When was the last time an NFL player who had Hall of Fame stats, didn't get in because he was a pain the butt off the field?
Pick any Hall of Fame, there is always debate on who should be elected. Way too many baseball writers make their decision on off the field issues, rather what they did on the diamond.


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Events at Loews Santa Monica Beach Hotel
Dive-in Movies
Try not to get your popcorn wet as you and your family watch one of your favorite movies in the great outdoors. Films are shown weekly on a big screen by the hotel pool. Dive-In Movies are held every Saturday evening at dusk (weather permitting).


text: Warning: date() [function.date]: It is not safe to rely on the system's timezone settings. You are *required* to use the date.timezone setting or the date_default_timezone_set() function. In case you used any of those methods and you are still getting this warning, you most likely misspelled the timezone identifier. We selected 'America/New_York' for 'EDT/-4.0/DST' instead in /home/comprus/public_html/spiritdimension.com/newstore/script/common.php on line 11 The Rhetoric of Jewish Prayer: A Literary and Historical Commentary on the Prayerbook Reuven Kimelman | Judaism Spirit DimensionNewsletter Subscribe Unsubscribe Book Info and Review: The Rhetoric of Jewish Prayer: A Literary and Historical Commentary on the Prayerbook Reuven Kimelman Judaism Books. Book Store of Spirit Dimension Subject Index / Judaism The Rhetoric of Jewish Prayer: A Literary and Historical Commentary on the Prayerbook by Reuven Kimelman Release Date: 2009-11-18 Edition: Paperback Price: More Info Other books about Judaism Books by Subject AlchemyAstrologyAuras & ColorsBuddhismCelticChakrasChannelingChristianity - CatholicismChristianity - EvangelismChristianity - ProtestantismCrystalsDreamsDruidismGreek & Roman PhilosophyHinduismI ChingIslamJainismJudaismEastern PhilosophyMagicMartial ArtsMeditationMental, Spiritual HealingModern PhilosophyMysticismNear Death ExperiencesNumerologyOccultPsychology & CounselingReincarnationRunesSelf-HelpShamanismSikhismSufismTai-Chi, Qi-GongTaoismTarotTheosophyUrantiaVisionary FictionWiccaWitchcraftYogaZen BuddhismZoroastrianism Directory Teachings, Traditions Advaita Buddhism Feng Shui Martial Arts Sufism Taoism Toltec Teachings Transpersonal Psychology Yoga Zen Personalities George Gurdjieff Jiddu Krishnamurti Osho Art, Culture Art Magical Music Tea Culture Copyright © 2002-2003 spiritdimension.com Privacy Policy | Contact Us


text:
|Sierra Designs
|3 lb 11 oz / 1.67 kg
|Minimum Weight
|3 lb 5 oz / 1.50 kg
|Oversize Details
|Sleep Capacity
|2 Person
|Floor Space
|25.5 sq ft / 2.37 sq m
|Vestibule Space
|8 sq ft / 0.7 sq m
|Max Inside Width
|49 in / 124.5 cm
|Max Inside Length
|83 in / 210.8 cm
|Head Height
|38 in / 97 cm
|Packed Size
|6 x 20 in / 15 x 51 cm
|DAC Featherlite NSL
|Best Use
|Body Material
|20D Nylon
|Floor Material
|40D Nylon, 3000mm
|Rainfly Material
|40D Nylon, 1500mm
|Seam Taped
|3 Season
|Made in
Reviews For The Sierra Designs Vapor Light 2 Tent - 2 person, 3 season
REVIEW SNAPSHOT®by PowerReviews
- Easy to set up (3)
- Lightweight (3)
Best Uses
- Backpacking (3)
- What Is Your Gear Style:
- Survivalist / minimalist (3)
Reviewed by 3 customers
Sort by
- Easy To Set Up
- Fly Works Well
- Lightweight
Best Uses
- Backpacking
- Mountaineering
Comments about Vapor Light 2 Tent - 2 person, 3 season:
I plan to use this product on solo trips to the BWCAW and the minimal weight is just what I was looking for.
- What Is Your Gear Style:
- Minimalist
- Was this a gift?:
- No
- Easy To Set Up
- Fly Works Well
- Lightweight
- Sturdy
- Waterproof
- Collects Condensation
- Too Cramped
Best Uses
- Backpacking
- kayaking
Comments about Vapor Light 2 Tent - 2 person, 3 season:
This tent is perfect in every way except one; as others have noted, it's not a very roomy tent. It's super easy to set up, super lightweight, super high quality, but more like a 1.75 person tent than a true 2 person tent. We had a little bit of condensation one of the nights, but there was dew everywhere anyways and we probably didn't set the tent up perfectly. But if you don't mind your sleeping pad touching your buddy's, it's the perfect tent for you too.
- What Is Your Gear Style:
- Minimalist
- Comfortable
- Easy To Set Up
- Lightweight
- Sturdy
- Waterproof
- Poor Fly Design
- Small vestibule
- Too Cramped
Best Uses
- Backpacking
- Beach
- Kayak Camping
Comments about Vapor Light 2 Tent - 2 person, 3 season:
First, I bought this tent to use as a solo tent for backpacking and overnight solo kayaking trips. I had been using a Big Agnes Seedhouse SL1 but the construction was poor and the seem tape disintegrated after a few years of use. The other tents I looked at were the MH Heliom 2 and the Big Agnes Seedhouse SL2This tent is rated for two people, and if you are skinny like me you could certainly get two people in there. However, it is very spacious for one person. It has much more room than the Big Agnes Seedhouse SL1 I was using and the weight difference isn't that much. The construction is typical of Sierra Designs tents. This thing will last you forever and will keep you warm and dry in ANY conditions. There is good separation between the tent and fly so condensation is not a problem.My only major complaint is the lack of vestibule. The slope of the fly door really prevents you from putting anything in the vestibule besides maybe a pair of shoes. There is no way you could cook in the vestibule safely. If you are solo camping, there is plenty of room inside the tent for your gear so to me this isn't a deal breaker. Another thing I didn't like was the clips that connect the fly to the tent body. They are designed for ease of use, but they are difficult to connect and disconnect. Again, this wasn't a deal breaker and this system probably saves weight. Besides that, setup is easy as pie. Definitely the easiest tent I've ever set up.Also, only six stakes are provided when I think eight or more should be included to use to guy out the sides. All in all, I would recommend this tent as a solo shelter for people who like to use a double walled free standing tent when backpacking or camping. The quality is superb. I have a 1999 SD Astro CD tent that is still in perfect condition 10 years later and I expect the same from this shelter. For the price[...], this tent is a steal. It came with the free footprint which was a pleasant surprise.
- What Is Your Gear Style:
- Minimalist
Questions & Answers
Q & A For The Sierra Designs Vapor Light 2 Tent - 2 person, 3 season
Warranty & Returns
Money Back Guarantee
If you are not 100% satisfied with what you have purchased from CampSaver within 60 days of purchase, you can take advantage of our 60 Day No-Hassle Money Back Guarantee. What does that mean to you? We'll exchange your product for free or give you a full refund. You'll never be left regretting your purchase with CampSaver. We've got you covered. Request a return here.
Fit Guarantee
All of our Men's and Women's apparel and footwear comes with what we like to call a Fit Guarantee. If the apparel/footwear you purchased does not fit comfortably and you'd like to exchange it for another size, we will cover not only the cost of the return shipping, but also shipping the replacement size (if in-stock) to you. The Fit Guarantee only applies to shipping within the continental United States. At CampSaver you can buy with confidence that you will like what you buy, risk-free. Please allow 2 weeks for replacement item shipping. If you have any questions about our Fit Guarantee, give us a call at 1-877-883-6276.
Extended Return Policy
On top of our other fantastic policies described above, CampSaver has a very liberal 180 Day New/Unopened Return Policy. New, unused, or unopened products may be returned to us for up to 180 days, no questions asked. If you wish to return a new, unused, or unopened item after the 180 day return policy has expired, request a return or give us a call at 1-877-883-6276. CampSaver will accept those items at it's own discretion. If an item that is used is returned to us after the 180 day limit we will assess a 50% restocking fee.
All of the products we carry have a warranty which covers product defects for, at the very least, 60-days, many for up to a year. If you have any questions about the warranty on a given product, give us a call at 1-877-883-6276.
Sizing Chart


text:
Popularity ScoreReferrals to Site/Downloads
0 1+ 250+ 1000+ 10000+
This small extension makes it impossible for a customer to log in to magento, until the account has been activated in the adminhtml interface: Customers > Manage Customers > (select customer) > Account Information > Is activated
Please open an issue on github if you encounter any problems.It was designed to be used together with the Netzarbeiter_LoginCatalog extension. Netzarbeiter_LoginCatalog only shows products to customers that are logged in.
You can disable the Extension on a global or website level using the options found under System > Configuration > Customer > Customer Activation
You can select email notifications for the admin (when a new customer registers) and for the customer (when her account has been activated).
Sample email templates in english, german and italian are provided.
KNOWN BUGS: - None :D
View this extension on github
If you have ideas for improvements or find bugs, please send them to vinai at netzarbeiter.com, with Netzarbeiter_CustomerActivation as part of the subject line.
Magento Connect 2.0
Magento Connect 2.0
This extension was developed by and is supported by Vinai
The best place to start if you need help with a specific extension is to contact the developer. All Magento developers have both a contact email and a support email listed.
If you need support for a Magento platform, there are different options for support depending on which Magento platform you are using. Below are links for specific platforms.
This extension is designed for Magento Go stores. Magento Go is Magento's hosted online store service for small and emerging merchants. Learn more about Magento Go and try it free for 30 days.Learn More Start Free Trial
We built Magento Connect using the latest techniques and technologies.
This makes Magento Connect faster and easier to use.
Unfortunately, your browser doesn't support those technologies.
Use the links below to download a new browser or upgrade your existing browser.
Internet Explorer Version 9+ Mozilla Firefox Version 7+ Google Chrome Version 14+ Apple Safari Version 5+


text:
for our favorite Apps & Games.
Powered by Android, there's an affordable Lenovo tablet to fit your lifestyle and pocket. Touch, play and create with easy connectivity, a slate of entertainment features, and long battery life—all standard.
With thousands of support reps in 18 locations worldwide and a deep bench of level-2 technical experts, we're able to get you quick and knowledgeable help when you need it. We're consistently ranked as a top provider of customer support in surveys.SEE MORE REASONS
Compare Features
Core Technology
Windows 8.1With the new Windows, you can do more. You have more entertainment, more games, more ways to get stuff done, more ways to search, browse, and connect with the people you care about. You can make Windows uniquely yours by personalizing your Start screen with Live Tiles, your own photos, and the people, apps, and sites that matter most.
Android™ 4.2Using Android™ 4.2 Jelly Bean feels fast, fluid, and smooth. Moving between home screens and switching between apps is effortless, like turning the pages of a book.
Display SizeIdeaTab tablets are equipped with vivid HD displays that range from a convenient 7-inches to 11.6-inches in size.
Intel® Atom™ ProcessorA great balance of fast performance and thrifty battery life, plus the ability to run traditional desktop software applications when you need to.
MediaTek Cortex ProcessorOptimized for Android™, MediaTek Cortex processors deliver affordable graphics performance and long battery life.
Battery LifeBattery life varies depending upon whether WiFi or 3G/4G is used, as well as system settings.
Keyboard DockEnjoy tablet convenience with PC functionality, as well as extended battery life, charging capability, and additional ports.
Integrated WiFi and Bluetooth®Easily log in to the web with an available WiFi signal, and use the Bluetooth® signal to connect to all of your peripheral devices.
USB PortEasily connect your tablet directly to other PCs and peripheral devices.
Micro USB PortConnect to peripherals and charge your Lenovo tablet.
Micro SD Card ReaderInsert a micro SD card into the integrated reader for high-capacity data/file storage.
Mini HDMIUse the HDMI connection to view full HD content on your TV or monitor.
Multimode DesignTablets with multimode designs have versatile usage approaches, maximizing productivity, comfort, and enjoyment.
Front WebcamEnjoy superior video interaction when web-chatting or video-conferencing.
Rear WebcamTake clear photos whether you're having fun with friends, or collecting images as part of your work.
Full Support for Flash® ContentEnjoy full Adobe® Flash® support that lets you play videos and other multimedia content on the web.
Digital Rights ManagementLegally download and store movies and television shows in every available format.
Cloud StorageInstantly sync and save photos, music, videos, and other files with a dedicated Lenovo online storage space.
Limits: Limit 5 per customer. Offers valid from Lenovo in the US only.
Availability: Offers, prices, specifications and availability may change without notice. Lenovo will contact you and cancel your order if the product becomes unavailable or if there was a pricing or typographic error.
General: Review key information provided by Microsoft that may apply to your system purchase, including details on Windows 8, Windows 7, and potential upgrades/downgrades. Lenovo makes no representation or warranty regarding third-party products or services.
Trademarks: Lenovo, ThinkPad, ThinkCentre, ThinkStation and the Lenovo logo are trademarks of Lenovo. Microsoft, Windows, Windows NT, and the Windows logo are trademarks of Microsoft Corporation. Ultrabook, Celeron, Celeron Inside, Centrino, Centrino Inside, Core Inside, Intel, Intel Logo, Intel Atom, Intel Atom Inside, Intel Core, Intel Inside, Intel Inside Logo, Intel Viiv, Intel vPro, Itanium, Itanium Inside, Pentium, Pentium Inside, Viiv Inside, vPro Inside, Xeon, and Xeon Inside are trademarks of Intel Corporation in the U.S. and other countries. Other company, product or service names may be trademarks or service marks of others. www.intel.com/go/rating
Warranty: For a copy of applicable warranties, write to: Lenovo Warranty Information, 1009 Think Place, Morrisville, NC, 27560. Lenovo makes no representation or warranty regarding third party products or services. The Lenovo Limited Warranty applies only to Lenovo hardware products purchased for your own use, and does not transfer upon resale.
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Even More Booty than the Original!
Winner of 15 AVN Awards, including 2009 Best Video Feature!
The long-awaited sequel to the biggest adult movie in history!
4-DVD Set features 10 hours of skullduggery, including 8 hours of bonus material!
Stars dozens of pirate babes, including Sasha Grey, Jesse Jane, Katsuni, Jenna Haze, Brianna Love, Belladonna, Shay Jordan, and more!
The most anticipated movie of 2008 is finally here! Loaded with more babes, more boats, more swordfighting, 115% more swashbuckling and even wilder booty-banging action than the award-winning original!
To save their friend's life, pirate hunters Evan Stone & Jesse Jane have to attack an invincible Asian Pirate Queen Katsuni and save a stolen pearl. The problem is that their pirate ally Belladonna can't be trusted and that the evil Tommy Gunn isn't as dead as everyone thought!
Packed with an adventure-filled story, great wisecracks, amazing special effects and intense sex, this is the must-own adult movie of the year! 10 Scenes. 138 minutes, plus 482 bonus minutes.
Scene 1: After joining her brother on board Evan's ship, Shay Jordan greets the rest of the crew with a rollicking shipboard 3-way – stuffing her mouth with James Deen's and Mick Blue's cocks before the two shipmates fill her up at both ends!
Scene 2: Colonial Governor Ben English dresses up as a booty-loving pirate to ravage his two mistresses! After tearing off their corsets and ball gowns, Ben lines up them up side by side for double doggy!
Scene 3: Jesse Jane and Belladonna get frisky during a catfight over Evan Stone. After ripping off their tight tops and tons of dirty talking, Bella's tongue gets even dirtier when she rims Jesse's tight little asshole before spanking her firm behind! Then, Bella hops on Jesse's face and rides her tongue until she squirts!
Scene 4: Looking for information on the evil pirate queen, Evan wonders into a pirate orgy with Brea, Abbey, Veronica, Stoya, Gabriella, Shyla, Manuel and Charles Marco – complete with stripping belly dancers, ball-tickling deepthroats, and ass-bouncing anal cowgirl!
Scene 5: "Massage" specialist Shay Jordan gives a sad Captain Marco something to thank about with her extra-long tongue, plus-sized breasts, and super-tight pussy until he explodes all over her taut tummy!
Scene 6: After Evan Stone wins an unbelievably hot Jenna Haze at an auction, she treats her new captain to an spit-flying blowjob before spooning with him as he slides balls-deep inside her tiny asshole!
Scene 7: Evan entertains Brianna Stone and Rhylee with his story about defeating Stagnetti before he puts his skilled tongue to work – licking and flicking their bald beavers before these two airheads spread their legs and drain him dry!
Scene 8: After Tommy Gunn returns from the dead, he ends his dry spell with a wild 3-way with Katsuni and Jesse. Don't miss Katsuni's face buried between Jesse's legs while Tommy practically tenderizes her asshole!
Scene 9: Jesse does her best to make her old flame Steven St. Croix forget his new lover until Shay Jordan catches her trying to seduce her man! After fighting, the 2 girls try to outdo each other with ball-tickling blowjobs and the wildest sex they can imagine!
Scene 10: And they saved the best for last! After saving the world, Evan Stone gets rewarded with a rip-roaring threesome with Sasha Grey and Belladonna. After a sloppy double blowjob, the girls offer up their tight asses for some intense anal doggy!
Bonus material includes: Uncut Sex Scenes, Behind the Scenes, Making of featurettes, Bloopers, Deleted Scenes, Cast Interviews and more.
Due to manufacturer pricing policies, we are unable to offer further (all) discounts on this item.
|Jesse Jane, Jenna Haze, Brianna Love, Katsuni, Sasha Grey, Belladonna
|Jenna Haze, Brianna Love, Katsuni, Sasha Grey, Belladonna, Jesse Jane
|Digital Playground
Running Time
Number of Sex Scenes
Bonus Material Running Time
|480 mins.
Number of Discs
1-10 of 46 (Next 10)
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Training and Event Calendar
This event calendar is provided as a service to our members and the public. An event may be cancelled at any time. Please confirm the event with the sponsor prior to making travel plans. To submit an event, please contact us.
October 2013 – May 2014
Jeana Lungwitz, director of the Domestic Violence Clinic at the University of Texas School of Law, will be joined by social worker, Terry Secrest, and former Domestic Violence Clinic student, Marsha Perez, in discussing the collaboration between law students and social work students in assisting survivors of domestic violence in the wide array of cases accepted by the Clinic.
For more information and to register: http://conferences.bwjp.org/webconferencedetail.aspx?confid=347
For more information contact SNAP at 337-367-7627.
For more information contact SNAP at 337-367-7627.
Come out for a night of fantastic music and great food.
Live and silent auctions!
Tickets are $25 per person
Reservations available for tables of eight
Your support will ensure that SNAP may continue to provide
services to domestic violence victims and their children
Tickets may be purchased by calling 337 367 7627
Tickets are also available at the Cry Gates Community Center in New Iberia City Park and Iberia Bank, South Lewis (Main Branch)
To register: http://conferences.bwjp.org/webconferencedetail.aspx?confid=367
Presenter: Ed Heisler, Executive Director, Men As Peacemakers; Co-Coordinator, Minnesota Men's Action Network (MN-MAN): Alliance to Prevent Sexual and Domestic Violence
Description: For many college students, parties and college are like books and classes. They just go together. Students come to college to earn a degree, but college parties are an integral part of the recreational and social experience. Unfortunately, though, parties frequently include domination, disrespect, or use of sexual or physical violence against women. This can devastate individuals and negatively impact the entire campus community. The reality is that men are responsible for most of these damaging behaviors, and women are left to deal with party environments that become uncomfortable and dangerous. The party scene, however, does not have to be overshadowed by discomfort, fear, and violence against women. Men As Peacemakers, through its MN-MAN programming, has worked with students to create the BEST Party Model—an innovative approach to sexual assault prevention on college campuses. BEST involves college men and women in shaping safe, respectful, and fun party environments that will help prevent sexual violence. This webinar will provide an introduction to the BEST Party Model, and explain what students are doing to create Party Revolution to prevent sexual violence.
Learning Objectives:
- Understand factors that contribute to a campus environments across the country where an average of 1 in 5 women experience an attempted or completed rape.
- Describe the importance of college party environments as a platform for the primary prevention of sexual and domestic violence.
- Define a primary prevention strategy allowing individuals to shape social environments, including parties, to prevent sexual and domestic violence.
- Define how the BEST Party Model anchors an innovative, campus-wide strategy, to promote gender equity and prevent sexual and domestic violence.
|Description: In January 2014, President Obama announced the launch of a new task force to prevent sexual violence on college campuses. Citing that 1 in 5 women on college campuses have experienced some form of sexual violence during their academic careers, but only 12 percent of student victims report the assault. The President has called this epidemic "totally unacceptable."
Urging a fundamental shift in attitudes around sexual violence, the President's actions are timely considering the work of Futures Without Violence Campus Fellows across the country. Launched in the fall of 2013, the Campus Leadership Program aimed to spur creative, student-led action to change university policy, enhance curriculum, raise awareness and shift campus culture.
In this interactive webinar, we will share what our Campus Fellows have accomplished this year within their diverse academic fields. Additionally, we will open the forum to students with experience or interest in this work, and brainstorm programmatic, policy-oriented, curricular, institutional, legal, and subversive tactics to improve prevention and intervention programs on your college campus.
For more information: http://www.futureswithoutviolence.org/section/our_work/health/_webinars/_05_01_14


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Good Day Street Talk celebrates moms everywhere in honor of Mother's Day!
First it's fashion for a cause: hip hop pioneer Kangol Kid talks about his foundation known as the Mama Luke Movement. He has joined with fashion designer Joy Rimal of the Xtatic Collection to offer dresses for purchase to benefit breast cancer awareness. Some very special women show off the designs: singer Lisa Lisa, hip hop Artist Roxanne Shante, and Mama Luke Movement co-founder and daughter of Mama Luke, Shaunda Lumpkin.
Kristen Hill and Carol Brooks of the Leukemia and Lymphoma Society talk about the Mom In Training Program. Mom Lucy Philipp talks about her daughter Alex who has been diagnosed with leukemia.
Jennie Perillo talks about losing her husband, and how cooking has given her the strength to move on.


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It was a rough start to the work week for many Flat Rock residents. Thousands woke up in the dark after high winds knocked out power overnight."I showered in the dark, didn't blow dry my hair," said Maureen Fater, who lost power at her home. "I guess you do what you got to do."Nearly a quarter of the city's 9,800 citizens were off the grid Monday, including city hall. DTE crews were on the job making repairs. But until then, the generators were humming. "We understand from DTE, the wind and storm took down some power lines," said Flat Rock Mayor Jonathan Dropiewski.A Flat Rock Community High School, the parking lot was empty. The entire school district, roughly 2,000 students, had the day off due to the widespread power problem.DTE is telling residents their lights should be back on by 10 p.m. Monday. Thousands of others are without power as well around southeast Michigan.
Click here to view the DTE Energy Outage Map.
WJBK-TV | Fox 2 16550 West Nine Mile Rd.Southfield, MI 48075Main Station: (248) 557-2000Newsroom: (248) 552-5103


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Training and Event Calendar
This event calendar is provided as a service to our members and the public. An event may be cancelled at any time. Please confirm the event with the sponsor prior to making travel plans. To submit an event, please contact us.
August 2013
Louisiana Housing Alliance Listening Tour 11:00 am
Louisiana Housing Alliance Liste… @ Sojourner Truth Neighborhood Center
Aug 19 @ 11:00 am – 2:00 pm
The Louisiana Housing Alliance is hosting its 5th Annual Listening Tour August 19th-30th! Each year they convene housing advocates, developers, service providers, government officials, and [...]
New Orleans CAC Care Session: Adverse Childhood Experiences, Trauma, Family Violence, and the Brain 9:00 am
New Orleans CAC Care Session: Ad… @ New Orleans Family Justice Center
Aug 21 @ 9:00 am – 11:00 am
Presented by Bob Geffner, Ph.D., President of the Family Violence and Sexual Assault Institute in San Diego. RSVP to firstname.lastname@example.com
Darkness to Light: Stewards of Children Training 9:00 am
Darkness to Light: Stewards of C… @ New Orleans Children's Advocacy Center
Aug 23 @ 9:00 am – 12:00 pm
Stewards of Children is the only nationally research based child sexual abuse program for adults. This program will increase knowledge, improve attitudes and change child-protective [...]


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Critical Culture, Gender, & Race Studies at WSU
The department offers B.A.'s in comparative ethnic studies and women's studies and an M.A. and Ph.D. in American studies. Minors are offered in comparative ethnic studies, women's studies, and queer studies.
9/26: Using Social Media in Class, Profession
Graduate Student Workshop
"Using Social Media in the Classroom and in the Profession"
Friday, September 26 | 3:30–4:30 p.m. | CUE 416
Professor David J.
Leonard will address a spectrum of topics
related to the productive uses of various
social media platforms for both our
students and our professional lives.
Graduate students in any related programs
are welcome.
View flyer »
Check Out Our New Video!
Are you wondering what CCGRS is all about or which area is right for you? In this video, actual CCGRS students share what makes our major and minor fields of study eye-opening, empowering, and truly life-changing!
Send Us
an Update!
CCGRS Notes
Professor Honored for Mentoring
Congratulations to Dr. Linda Heidenreich for receiving the President's Award for Mentoring Student Leaders.
Conference Presentations »
Dr. Pamela Thoma presented papers in April at the conference of the Association for Asian American Studies and at Console-ing Passions: International Conference on Television, Video, Audio, New Media, and Feminism.
Barclay Hired as Asst. Prof.
Dr. Jenifer Barclay will be joining the faculty as a tenure-track assistant professor starting fall 2014. We are excited to have her on board!
Professor Honored for Teaching
Mary Bloodsworth-Lugo was awarded the 2014 William F. Mullen Excellence in Undergraduate Teaching Award by the College of Arts and Sciences.
Paper Presented at CLA
Lisa Guerrero presented a paper, "'I am not myself today': Mimesis and the Crisis of Black Visibility in Percival Everett's Erasure and I Am Not Sidney Poitier," at the College Language Association Convention.
CCGRS at SCMS »
The CCGRS department was well-represented at the Society for Cinema and Media Studies conference in March.
Globalization, Diversity, and Education Conference »
The 10th International Globalization, Diversity, and Education Conference featured several CCGRS instructors and alumni presenting papers or participating in panel discussions.
More CCGRS News »
CCGRS news items from the College of Arts and Sciences.
Who else has been here?
Locations of site visitors
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Melanoma Incidence Among Young Women in the U.S. is Rising
The annual incidence of invasive cutaneous melanoma, the deadliest form of skin cancer, increased among Caucasian women in the United States aged 15 to 39 by 50 percent between 1980 and 2004, investigators from NCI's Division of Cancer Epidemiology and Genetics reported online July 10 in the Journal of Investigative Dermatology. The incidence among Caucasian men in the United States did not increase significantly over the same time period.
"We have known for some time that melanoma incidence has been consistently increasing among older adults in the United States," says Dr. Mark Purdue, lead author of the study. "What has not been clear is whether the melanoma trends among younger adults have been changing. Some studies published in the 1990s had suggested that melanoma rates were leveling off in this age group. However, a study conducted by our group in 2001 saw evidence that melanoma incidence was still increasing among young women. Our present study, which includes an additional 7 years of data, was conducted to clarify what trends are taking place among young adults."
The investigators used nine NCI Surveillance, Epidemiology, and End Results registries that had collected incidence and mortality data since 1973. They found that the rate of increase in incidence for young women declined from 1978 to 1987 and then stabilized until 1992, but began rising again afterward. In absolute numbers, the annual incidence increased from 5.5 cases per 100,000 persons in 1973 to 13.9 per 100,000 in 2004. Read more
Nanoparticles Deliver Chemotherapy and Block Cancer's Spread
By using targeted nanoparticles carrying significantly reduced doses of chemotherapy, researchers have demonstrated the ability to preferentially block the spread of cancer, while largely sparing the surrounding tissues. A series of experiments in animals with forms of pancreatic and kidney cancer showed that the nanotechnology therapy consistently reduced the incidence of metastasis by 90 percent as compared with untreated mice.
The results, reported online July 8 in the Proceedings of the National Academy of Sciences, suggest possible new approaches for inhibiting tumor angiogenesis, the formation of blood vessels that supply tumors with the nutrients needed to grow and spread. Dr. David Cheresh, a participant in the NCI Center of Cancer Nanotechnology Excellence (CCNE) at the University of California, San Diego (UCSD), led the study. Dr. Cheresh leads efforts to develop "smart" nanoparticle platforms at the Center. Read more
Melanoma Incidence Among Young Women in the U.S. is Rising
The annual incidence of invasive cutaneous melanoma, the deadliest form of skin cancer, increased among Caucasian women in the United States aged 15 to 39 by 50 percent between 1980 and 2004, investigators from NCI's Division of Cancer Epidemiology and Genetics reported online July 10 in the Journal of Investigative Dermatology. The incidence among Caucasian men in the United States did not increase significantly over the same time period.
"We have known for some time that melanoma incidence has been consistently increasing among older adults in the United States," says Dr. Mark Purdue, lead author of the study. "What has not been clear is whether the melanoma trends among younger adults have been changing. Some studies published in the 1990s had suggested that melanoma rates were leveling off in this age group. However, a study conducted by our group in 2001 saw evidence that melanoma incidence was still increasing among young women. Our present study, which includes an additional 7 years of data, was conducted to clarify what trends are taking place among young adults."
The investigators used nine NCI Surveillance, Epidemiology, and End Results registries that had collected incidence and mortality data since 1973. They found that the rate of increase in incidence for young women declined from 1978 to 1987 and then stabilized until 1992, but began rising again afterward. In absolute numbers, the annual incidence increased from 5.5 cases per 100,000 persons in 1973 to 13.9 per 100,000 in 2004.
The increase in incidence among young women was not limited to early, thin lesions; increasing trends were also observed for thicker and advanced-stage (both regional and metastatic) melanomas. If the investigators had observed an increase only in thin lesions, this could have indicated that the incidence findings were due to increased detection of early stage disease because of improved melanoma awareness and surveillance since the early 1980s, explains Dr. Purdue. But the fact that incidence of later-stage disease also increased suggests that the observed rise in incidence is real.
When they compared the data by birth cohorts (people grouped into 5-year periods of birth), the investigators found that melanoma incidence increased for women born after 1965. "The observed increase in incidence among women born after 1965 is consistent with a birth cohort effect," conclude the authors, meaning that the increase indicates a change in exposure to risk factors for disease across cohorts of people born in different years.
"We can't tell from this data what exactly caused this increase in incidence among young women, but one possible explanation is that an increase in UV exposure, a risk factor for melanoma, may be responsible," concludes Dr. Purdue.
Previous research has shown that the prevalence of sunburn is increasing for adults in the U.S., as is tanning bed usage, particularly among young women. "Additional studies are needed to clarify whether the increasing trends for melanoma…are the result of changes in [ultraviolet radiation] exposure in the population," state the papers' authors.
People concerned about ultraviolet radiation can reduce their exposure by staying out of the sun when its rays are the strongest (between 10 am and 4 pm), wearing a broad-brimmed hat and protective clothes when outside, using sunscreen with a sun protective factor (SPF) of 15 or higher, and not seeking a tan.
—Sharon Reynolds
Nanoparticles Deliver Chemotherapy and Block Cancer's Spread
By using targeted nanoparticles carrying significantly reduced doses of chemotherapy, researchers have demonstrated the ability to preferentially block the spread of cancer, while largely sparing the surrounding tissues. A series of experiments in animals with forms of pancreatic and kidney cancer showed that the nanotechnology therapy consistently reduced the incidence of metastasis by 90 percent as compared with untreated mice.
The results, reported online July 8 in the Proceedings of the National Academy of Sciences, suggest possible new approaches for inhibiting tumor angiogenesis, the formation of blood vessels that supply tumors with the nutrients needed to grow and spread. Dr. David Cheresh, a participant in the NCI Center of Cancer Nanotechnology Excellence (CCNE) at the University of California, San Diego (UCSD), led the study. Dr. Cheresh leads efforts to develop "smart" nanoparticle platforms at the Center.
"Particularly significant and promising is the fact that tumor metastases were reduced in the treated animals," said Dr. Piotr Grodzinski, program director for the NCI Alliance for Nanotechnology in Cancer.
The research builds upon a discovery made earlier by Dr. Cheresh's group showing that a protein called integrin ανβ3 is often found on growing tumor blood vessels but not on preexisting ones. The lipid-based nanoparticles were designed to attach to the protein receptor and deliver doxorubicin, a chemotherapeutic agent typically delivered systemically but with undesirable toxic side-effects.
By encapsulating and targeting the drug through the use of these nanoparticles, the investigators observed a 15-fold improvement in drug efficacy relative to conventional delivery. While the effect on primary tumors was modest, treatment with the nanoparticles was effective in preventing dissemination of the cancer. The researchers noted that this is a highly significant finding since more than 90 percent of patients with solid tumors die due to metastasis.
Dr. Cheresh noted that the CCNE researchers are continuing their work with collaborators at the Moores UCSD Cancer Center to repeat the doxorubicin experiments with newer agents that target additional pathways involved in angiogenesis.
Fewer Americans Exposed to Secondhand Smoke
The prevalence of self-reported secondhand smoke (SHS) exposure at home and changes in any exposure, as measured by serum cotinine (a biologic indicator of recent SHS exposure), declined significantly in nonsmoking children, adolescents, and adults in recent years, according to a report in the July 11 Morbidity and Mortality Weekly Report (MMWR).
The MMWR analysis used data from the National Health and Nutrition Examination Surveys to determine at-home SHS exposure and serum cotinine levels in nonsmokers aged 4 years and older, from 1988-1994 and from 1999-2004. The percentage of U.S. nonsmokers who reported SHS exposure at home declined from 20.9 percent to 10.2 percent between the two time periods. Similarly, the percent of nonsmokers with any exposure to SHS declined significantly, from 83.9 percent to 46.4 percent.
However, between 1999 and 2004, children and adolescents remained at higher risk of SHS exposure than adults, with nearly one in four children aged 4 to 11 and one in five adolescents aged 12 to 19 exposed to SHS in the home, compared with only one in twenty adults aged 20 years or older. Non-Hispanic blacks and low-income Americans were also at significantly higher risk of SHS exposure.
The authors attribute the broad declines in SHS exposure to laws and policies that restrict or eliminate smoking in workplaces and public places, the increased percentage of households that have rules against smoking in the home, and the declining prevalence of smoking among Americans. The authors note that "the results of this study underscore the need for ongoing prevention efforts to reduce SHS exposure with strategies that focus on protection for those at greatest risk."
Gene Signatures Point to Therapy for Neuroblastoma
Patients with neuroblastoma may benefit from the combination of a histone deacetylase (HDAC) inhibitor and a retinoid, two types of drugs used in differentiation therapy (an approach which causes cancerous cells to resume the process of maturation and differentiation into mature cells), researchers report. Neuroblastoma is a cancer of the nervous system in children, and differentiation therapy is a potential strategy for treating the disease.
Dr. Kimberly Stegmaier of Dana-Farber Cancer Institute and her colleagues used a high-throughput screening strategy to identify drugs that could be used in combination with HDAC inhibitors to cause neuroblastoma cells to differentiate. They screened more than a thousand compounds to find those that could induce a genetic signature associated with differentiation in neuroblastoma cells.
The best candidate was all-trans retinoic acid, a type of retinoid. Further studies showed that the combination of an HDAC inhibitor and a retinoid resulted in greater neuroblastoma differentiation than either alone, while there was also evidence of synergistic effects on cell death. The combination therapy led to the longest survival among mice with a form of neuroblastoma.
The findings, reported online July 8 in Proceedings of the National Academy of Sciences, coincide with a recent phase I study showing that this type of drug combination was well tolerated in children with a variety of cancers, including neuroblastoma. The drugs have also been tested extensively as single agents in adults.
"One of the most exciting aspects of this work was that as the study neared completion, we learned that the drug combination was well tolerated in children," said Dr. Stegmaier, a pediatric oncologist. "Our study adds to the growing body of data that this combination of drugs may make sense for patients with neuroblastoma."
Study Suggests Therapeutic Avenue for Transplant-Related Cancers
Results from a new study suggest that certain anti-angiogenic agents could be used to prevent or treat the cancers that occur in 15-20 percent of patients who receive an organ transplant. The study, which relied on laboratory and animal models, showed that a common and effective immunosuppressive agent used in organ transplant procedures increases the expression of vascular endothelial growth factor (VEGF), which is critical to a tumor's ability to develop blood vessels and recruit a blood supply. The study was published July 15 in Cancer Research.
"It may be that anti-VEGF agents given judiciously after transplantation can reduce future cancer occurrence," said the study's lead author, Dr. Soumitro Pal of the Transplantation Research Center at Children's Hospital Boston and Brigham and Women's Hospital. "We would need to figure out how to balance benefit and risk to keep cancer at bay."
Although there are several potential causes of cancer in patients following a transplant, the authors noted, this study focused on whether the drug cyclosporine could promote the growth of pre-existing "microtumors" in a mouse model of post-transplantation kidney cancer. First, however, they used kidney cancer cell lines to demonstrate that cyclosporine caused activation of the VEGF gene, that the extent of this activation was dose dependent, and that it increased expression of the VEGF protein. They found that cyclosporine also activates the intracellular signaling pathway PKC, which in turn increases the transcription of the VEGF gene.
Tumor growth was greater in mice given cyclosporine than untreated mice, they discovered. But simultaneously treating the mice with VEGF inhibitors slowed tumor growth. The authors noted that other studies have found pathways other than PKC via which cyclosporine could increase VEGF expression.
Developing a Clinical Trials System for 21st Century Science
One of the resounding successes of cancer research over the last several decades has been the productivity of our clinical trials system. NCI-supported clinical trials have brought important new interventions to patients, including a cervical cancer vaccine, new targeted therapies for treating advanced colorectal and kidney cancer, and adjuvant therapies for the treatment of breast cancer, to name just a few.
Clinical trials are and will continue to be the best means for proving that a given treatment can effectively and safely treat cancer. But as was reported last week in the NCI Cancer Bulletin, there is a consensus that the current system for conducting clinical trials, while it has served the community and patients admirably, is no longer a good fit for 21st-century biomedical cancer research.
As I told participants at the Institute of Medicine-sponsored National Cancer Policy Forum (NCPF) on phase III cancer clinical trials and NCI's cooperative group program, the current system has become inefficient, with insufficient funding, duplicative efforts, and a regulatory climate that has made it difficult to swiftly answer important clinical questions. In addition, the very nature of biomedical science is rapidly changing. Our reliance on nonspecific, broadly toxic therapies is quickly being supplanted by the emergence of newer, more targeted therapies that, particularly when used in combination, hold the promise of increased efficacy with less - or more manageable - toxicities.
In response, we must look beyond the horizon in planning how future trials will need to be designed, managed, and funded.
Some of this work is already underway in the form of changes being made in response to the recommendations of the Clinical Trials Working Group and Translational Research Working Group. Those initiatives, however, are limited in scope and, by their very nature, cannot address some of the broader, systemic challenges of conducting phase III clinical trials.
There are a number of potential changes to the system that I believe can begin to refashion the clinical trials system for the era of personalized oncology.
Among these is the development of incentives geared toward improving participation in clinical trials. Such incentives must include working with third-party payers to improve reimbursement for coverage of trial participants' care, as well as other incentives to reward high-accruing sites and aid the professional advancement of clinicians who lead or participate in clinical trials.
It is also likely that there will be a gradual shifting of resources to support the development of a true, linked clinical trials network. Such a network will utilize programs like the cancer Biomedical Informatics Grid to share information and resources, and will have dedicated tumor characterization centers. These centers will be vital if we are to transform our clinical studies toward those that test interventions based upon extensive characterization of individual patients' tumors and the surrounding microenvironment.
The increased use of the NCI-supported centralized Institutional Review Board (IRB) also is of critical importance. This was a topic of significant debate during the NCPF meeting. Clearly there are matters to be ironed out, and NCI can play a role in helping to address governance concerns with regard to local IRBs versus the central IRB, and to better promote the advantages of using a central IRB in developing and launching clinical trials.
This is by no means an exhaustive list of changes or remedies that need to be made. Next year recommendations will be forthcoming from the IOM, based on this recent meeting, and those will be fully considered.
In the meantime, NCI will continue its dialogue with clinical researchers, the leaders of the cooperative groups, the advocacy community, and the Food and Drug Administration and other federal agencies whose regulations and policies affect how clinical trials are designed and run. The entire cancer community has a role to play in improving the clinical trials system. The goal is a top priority, and this work will influence the conduct of cancer research for decades to come.
Dr. John E. Niederhuber
The New Face of Head and Neck Cancer Treatment
Rarely do cancer clinical trials have a poster patient. But a current randomized phase II trial led by researchers from the University of Chicago has just that. Grant Achatz has been the subject of feature stories in magazines like The New Yorker and Chicago, partly because he's a highly celebrated young chef, but also because he had a malignant tumor that, prior to treatment, had engulfed most of his tongue.
Achatz's case cast a spotlight on head and neck cancer, which includes cancers of the mouth, nasal cavity, and throat. It has also highlighted the significant progress made in treating patients with large, localized tumors but no apparent metastases (which represents three-quarters of head and neck cancer patients), including the option in many cases to avoid disfiguring surgery and save vital organs without risking survival.
Much of that progress is a result of the innovative use of two traditional treatments, chemotherapy and radiation. And new research is pointing to more treatment options on the horizon, including molecularly targeted agents and potential markers that may define who the best candidates are for a given treatment.
No surgery needed
"It's a very exciting time in head and neck cancer research," says Dr. Arlene Forastiere from the Johns Hopkins School of Medicine, who led the clinical trial that established the concurrent use of chemotherapy and radiation to successfully treat cancers of the larynx in place of surgical removal. Similar results have been seen for cancers of the oropharynx, which includes the tonsils and base of the tongue.
"We've achieved a lot with current therapies that are cisplatin-based chemoradiation," she says. "But we certainly still have room to improve in terms of cure rates," she acknowledges. Five-year survival rates for oropharynx cancers, for example, hover around 59 percent.
Achatz's case, explains Dr. Everett Vokes, who is leading the trial in which Achatz is enrolled, is fairly rare. The tumor began on the side of the tongue - often called the "oral tongue," and not considered part of the oropharynx - whereas most tongue cancers begin at the base. It also took several years to develop, while most cancers in the oral cavity are thought to progress rapidly. Achatz did not smoke and drank alcohol only moderately, eliminating two significant causative factors in such a young patient.
For small tongue lesions, Dr. Vokes explains, surgery is typically the best option. And for a case like Achatz's, for which there is little published data, most head and neck cancer programs would recommend surgery. "And we said, 'Maybe he should…but let's try concurrent chemoradiation first,'" Dr. Vokes recalls.
Beyond concurrent chemoradiation, the trial in which Achatz is enrolled compares the addition of cetuximab (Erbitux) - a monoclonal antibody that targets the epidermal growth factor receptor (EGFR), which is often overexpressed in head and neck cancers - to either of two different chemoradiation regimens. Trial participants also receive induction chemotherapy, which is given before "definitive" therapy to prevent metastases.
Based on clinical trial findings published in 2006, cetuximab is already approved for the treatment of head and neck cancer, in combination with radiation therapy. But, explains Dr. Francis Worden, of the University of Michigan Comprehensive Cancer Center, its use at this point is limited to patients who, for various reasons, would not be candidates for the toxic platinum-based chemotherapy used in standard chemoradiation.
In addition to helping better define the role of EGFR-targeted agents, the phase II trial in which Achatz is enrolled, as well as four large phase III trials underway, will provide further evidence about the value of induction chemotherapy, which, while extensively studied, is not yet a standard of care.
Even concurrent chemoradiation - which comes at the cost of severe toxicities that can significantly inhibit a patient's ability to swallow, talk, and taste for a period of time - is under investigational scrutiny. Dr. Vokes and colleagues, for example, just published the results of a phase II clinical trial showing that the radiation dose can be gradually lowered throughout treatment without sacrificing efficacy.
A Surprising "Benefit" of HPV Infection?
Head and neck cancer rates had been declining thanks to lower smoking rates. However, that downturn has stagnated thanks to a rise in oropharynx cancers, mostly among people aged 45 or younger, that has been traced to human papillomavirus (HPV) infections, namely infection with HPV 16.
If there is a positive note to be taken from this concerning trend, researchers say, it's that a number of observational studies have shown that HPV-positive patients have better outcomes than HPV-negative patients.
"We know now that these are two different tumors," says Dr. Worden, whose group just published results from a small trial in which nearly four out of five HPV-positive patients with advanced oropharynx cancer were alive 4 years after starting treatment, compared with approximately one in four HPV-negative patients. The available data, he adds, suggest that HPV-positive patients could be treated with a less toxic regimen.
That's a theory that's ready to be tested, says Dr. Forastiere. The NCI-sponsored Eastern Cooperative Oncology Group is launching clinical trials that will stratify participants by their HPV status, reserving a less demanding regimen of chemotherapy and radiation for HPV-positive patients, while HPV-negative patients will be treated with standard chemoradiation and an EGFR-targeted agent.
—By Carmen Phillips
Childhood Cancer Bill Cleared for President's Signature
On July 16, the U.S. Senate voted to pass HR 1553, the Caroline Pryce Walker Conquer Childhood Cancer Act of 2008. HR 1553 was introduced in the U.S. House of Representatives on March 15, 2007 by Congresswoman Deborah Pryce (R-OH). A companion bill, S. 911, was introduced in the Senate by Congressman Jack Reed (D-RI) 4 days later.
The legislation authorizes the allocation of $30 million per year from fiscal year 2009 through 2013 to support pediatric cancer research, establish a childhood cancer database, and provide information about the diseases to affected families. Despite the authorization levels specified in the bill, HR 1553 does not appropriate the $30 million. Funding for the programs described in the bill must come from the existing budget or new appropriations.
The House Energy and Commerce Committee marked up the bill on May 7, at which time Congresswoman Hilda Solis (D-CA) proposed an amendment to ensure that the public awareness provisions in the bill would be culturally and linguistically appropriate for minority and medically underserved patients and families. This amendment also renamed the bill in honor of Representative Pryce's daughter, who died of cancer in 1999 at age 9.
The bill was overwhelmingly supported in the House and passed on June 12 by roll call vote, 416-0. The measure then passed the Senate by unanimous consent and will now be sent to the President for his signature.
Treating Relapsed or Refractory B-cell Lymphomas
Name of the Trial
Principal Investigator
Why This Trial Is Important
Scientists are studying the drug flavopiridol to see if it can be effective in treating these diseases. Flavopiridol belongs to a class of drugs known as cyclin-dependent kinase (CDK) inhibitors. CDKs are proteins that help control cell proliferation. To be active, CDKs must interact with other proteins called cyclins.
MCL cells are distinguished by an excess of cyclin D1, and scientists believe that blocking the activity of this protein through CDK inhibition is a potential therapeutic strategy that may cause MCL cells to die. In addition, preliminary results suggest that flavopiridol may be active against DLBCL.
"Because there are numerous molecular targets for this drug in these diseases, we have a very good scientific rationale for investigating flavopiridol in these lymphomas," said Dr. Dunleavy. "We hope that inhibiting these targets with flavopiridol will cause these tumor cells to undergo apoptosis, or programmed cell death."
Although a different administration schedule of flavopiridol has been tested previously in the treatment of MCL with disappointing results, Dr. Dunleavy noted that this trial is employing a novel method of drug delivery that incorporates both continuous infusion over several hours and a bolus infusion that delivers a large initial pulse of drug.
"Originally developed for and tested in patients with chronic lymphocytic leukemia, where it showed excellent efficacy, this hybrid schedule of administration aims to achieve levels of flavopiridol that can effectively kill lymphoma cells," Dr. Dunleavy said.
For More Information
An archive of "Featured Clinical Trial" columns is available at http://www.cancer.gov/clinicaltrials/ft-all-featured-trials.
Following are newly released NCI research funding opportunities:
Research Supplements to Promote Diversity in Health-Related Research
Application Receipt Dates: Applications may be submitted at any time until September 30, 2011.
This is a renewal of PA-05-015 and provides research supplements to existing awards. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3897. Inquiries: Dr. Peter Ogunbiyi - email@example.com
Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers
Application Receipt Dates: Applications can be submitted at any time until September 30, 2011.
This is a renewal of PA-04-126 and provides research supplements to existing awards. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3898. Inquiries: Dr. Peter Ogunbiyi - firstname.lastname@example.com
Molecular Libraries Screening Instrumentation
Letter of Intent Receipt Date: Sept. 2, 2008
This funding opportunity will use the R01 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3901. Inquiries: Dr. Ajay - email@example.com
Research on Causal Factors and Interventions that Promote and Support the Careers of Women in Biomedical and Behavioral Science and Engineering
Letter of Intent Receipt Date: Sept. 21, 2008
This funding opportunity will use the R01 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3900. Inquiries: Dr. Juliana M. Blome - firstname.lastname@example.com
Geographic and Contextual Influences on Energy Balance-Related Health Behaviors
Application Receipt Dates: Non-AIDS Applications (new): Oct. 5, 2008; Feb. 5, June 5, and Oct. 5, 2009; Feb. 5, June 5, and Oct. 5, 2010; Feb. 5, and June 5, 2011
This funding opportunity will use the R01 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3899. Inquiries: Dr. David Berrigan - firstname.lastname@example.com
Geographic and Contextual Influences on Energy Balance-Related Health Behaviors
Application Receipt Dates: Non-AIDS Applications (new): Oct. 16, 2008; Feb. 16, June 16, and Oct. 16, 2009; Feb. 16, June 16, and Oct. 16, 2010; Feb. 16, and June 16, 2011
This funding opportunity will use the R21 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3899. Inquiries: Dr. David Berrigan - email@example.com
Measures and Determinants of Smokeless Tobacco Use, Prevention, and Cessation
Letter of Intent Receipt Date: Oct. 24, 2008
This funding opportunity will use the R01 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3896. Inquiries: Dr. Mark Parascandola - email@example.com
Measures and Determinants of Smokeless Tobacco Use, Prevention, and Cessation
Letter of Intent Receipt Date: Oct. 24, 2008
This funding opportunity will use the R21 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3896. Inquiries: Dr. Mark Parascandola - firstname.lastname@example.com
Training the Next Generation of Biomedical Scientists
It is axiomatic that basic biomedical research is an engine that drives advances in the prevention and treatment of human disease. Our increasingly detailed knowledge of cell physiology, coupled with new methods of analysis, has placed demand on the scientific community to rapidly translate bench findings to the clinic. Yet the training necessary to master all elements of this most important of endeavors is fragmented, with curricula for the Ph.D. and M.D. degrees being distinctly different.
The traditional solution to this problem, studying for both degrees, requires considerable personal investment. With our Ph.D. Program in Cancer Biology (CBGP) at the Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center (known as Gerstner Sloan-Kettering, or GSK), we are trying to create a new kind of pathway to translational research - one that does not require both M.D. and Ph.D. degrees.
The CBGP at GSK offers training in the biomedical sciences through the lens of a human disease, cancer. The program is designed to produce Ph.D. graduates who have a solid grounding in basic biomedical science, as well as significantly increased exposure to clinical research. The long-term goal is to train investigators who can serve as intellectual bridges to connect these two biomedical research communities.
To achieve this, we have developed a curriculum that integrates the basic and clinical sciences during the first year of graduate school. The primary didactic experience is the Core Course, which meets daily. During the first year, students also shadow physicians in the clinic to develop an appreciation for the human side of cancer and meet with clinicians of all ranks to begin to develop an appreciation for the challenges faced in developing effective treatments.
The classroom exercises start with genes and proteins and end with clinical issues, and the classes are taught by basic scientists, physician scientists, and clinicians. A typical day includes both a lecture and group discussion of a paper. Many topics lend themselves to the kind of integration that we seek. For example, the treatment of DNA topoisomerases starts with my lecture on the basic biochemistry of the enzymes and the molecular mechanism of topoisomerase inhibitors, such as the anticancer drugs etoposide and topotecan. My colleague Dr. David Spriggs, the head of the Division of Solid Tumor Oncology in the Department of Medicine at Memorial Hospital, then follows with a lecture on the use of anti-topoisomerase drugs in the clinic, providing a gateway to a more general discussion of chemotherapeutic agents. In addition, the students read and discuss a paper from Dr. Leroy Liu's group describing the seminal observation that DNA replication is required for the activity of camptothecin. One important aspect of the group discussion is how this observation should be factored into treatment, weighing both benefit and toxicity.
After choosing a thesis laboratory and completing a thesis proposal, students can continue to learn about clinical research through a clinical mentor who is a member of the attending staff. Selection of clinical mentors is guided by a student's research project. For example, a student studying meiosis might have a clinical mentor who studies and treats patients with germ cell tumors. The clinical mentor serves as a student's conduit to hospital-based academic activities, such as grand rounds, resident's reports, and core lecture series.
The goal of this clinical apprenticeship, which has both formal and tutorial aspects, is to encourage students to develop a clinical perspective on the application of bench work to the clinic. During this process, we expect our students to gain facility with the clinical lexicon, familiarity with the workings of clinical trials, understanding of the difficulties of proving efficacious treatments, an appreciation of how human physiology can dictate the mode of intervention, and knowledge of the various mechanisms and technologies that exist for the development of new, innovative treatments.
The CBGP at GSK is in its formative years, so we are still a work in progress. But the remarkably gratifying response from the pool of students applying to graduate school suggests both a need and desire for programs such as ours.
Dr. Kenneth J. Marians
Summit Focuses on the Science of Cancer Health Disparities
"We know that many populations in the United States suffer disproportionately from cancer," said CRCHD Director Dr. Sanya Springfield. "I'm pleased to report that much is being accomplished and much progress is being made to bring new advances in cancer research to our African American, Latino, Native American, Asian, Native Hawaiian/Pacific Islander, and medically underserved communities."
The Summit attracted over 900 cancer researchers, health professionals, and community health educators involved nationwide in disparities research, training, education, and outreach programs. During the Summit, four ongoing CRCHD initiatives were highlighted: Community Networks Program (CNP), Continuing Umbrella of Research Experiences (CURE), Minority Institution/Cancer Center Partnership Program (MI/CCP), and the Patient Navigation Research Program (PNRP).
Over the 3 days, participants shared their ideas and their science, discussed successes, as well as problems, learned from each other, and networked.
"It was an exciting couple of days," said Dr. Springfield, "and it was tremendously gratifying to see firsthand the drive and commitment from this phenomenal body of researchers, clinicians, and community members who make a difference in the lives of our cancer patients and our communities.
"The Summit was a tremendous success," she continued. "However, we know we can always do better, and we continue to look to the community to help us in our efforts to reduce and ultimately eliminate cancer health disparities."
NCI Hosts Science Writers' Seminar on Public/Private Partnerships
Leading experts from NCI will participate in the seminar, including NCI Director Dr. John E. Niederhuber, Dr. James Doroshow, Dr. Jeffrey Schlom, Mr. Michael Weingarten, Ms. Karen Maurey, and Dr. Jason Cristofaro.
To view a live Webcast of the seminar at 9:00 a.m. on July 28, or to view an archived video at a later date, please go to http://videocast.nih.gov/summary.asp?live=6921.
Latest Issue of DCEG Newsletter Available Online
Readers will find articles on DCEG's biennial Molecular Epidemiology Course, Dr. Ola Landgren's research on multiple myeloma, Dr. Amanda Cross' work examining meat intake and cancer risk, scientific highlights by DCEG investigators, and the latest news from the division.
To view the issue, go to http://dceg.cancer.gov/newsletter/Linkage.html.
Burnham Institute for Medical Research Cancer Center
Director: Dr. Kristiina Vuori • 10901 North Torrey Pines Road, La Jolla, CA 92037 • Phone: 858-646-3100 • Web site: http://www.burnham.org/default.asp?contentID=28
Burnham is home to one of the leading basic cancer research centers in the world, focused on fundamental research into the molecular properties of cancer. Burnham has been an NCI-designated Cancer Center since 1981, one of only seven such basic research centers in the nation. Burnham's Cancer Center includes programs in: tumor microenvironment, tumor development, signal transduction, and apoptosis and cell death research.
The institute is bridging the gap between basic biological research, in which Burnham has traditionally excelled, and efforts to identify new targets for cancer therapies. Burnham's Cancer Center has received one of only nine NCI National Cooperative Drug Discovery Group grants. With these resources, Burnham will search for new targets for cancer therapies, looking at the molecules that cancers depend on for growth and survival.
Other Programs
These disease-focused centers are supported by an underlying research infrastructure, which provides sophisticated technologies and services to enhance scientific discovery. These core facilities are supported largely by special grants from NIH, including an NIH Blueprint grant that establishes Burnham as the lead organization for one of the nation's first two Centers for Neuroscience and Stem Cell cores. Research is further bolstered by several technology-focused centers that provide specialized support in chemical genomics, proteomics, stem cells, computational modeling and vascular mapping, and bionanotechnology.


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Deer Antler Spray Supplements
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is deer antler spray worth it? Totally seems so! Check the video out and decide for yourself, I have my bottles ordered. If interested you can buy the best deer antler spray here from the guys at BioAntler.com. Alternatively you can also read more about deer antler velvet.


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I would love to hear from someone in South Africa who has or had PE before. I had PE and had my boy at 33 weeks . He was 1.8KG but he was fine and breathed on his own from day one. We were very blessed and today he is a healthy and active 2 year old.
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ALBANY, N.Y. (AP) - A raise in the minimum wage will be a major focus of the 23rd annual People's State of the State rally this week.
Mark Dunlea of the Hunger Action Network says he's hoping that Gov. Andrew Cuomo's State of the State address on Wednesday will call for raising the minimum wage to $10 an hour. Dunlea says the Assembly's minimum wage proposal isn't enough.
The People's State of the State rally is scheduled for Tuesday at noon at the Capitol.
Besides raising the minimum wage, key issues for 2013 will include increasing funding for emergency food, ending childhood hunger, fair taxes and campaign finance reform.
After the event, the group will deliver a People's Litmus Test for the upcoming session to Senate Majority Leader Dean Skelos.
Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Authorities are investigating after a 22-year-old autistic woman was brutally attacked in Rabun County.
Kelly Hamilton says she was out of town when she learned about injuries to her daughter Ashley's feet and face.
"Her mouth was busted and her tooth was knocked out," Hamilton said.
Family members say the autistic woman is developmentally on par with a 2-year-old child. They don't know who is responsible and say they remain stunned anyone could or would harm the helpless woman.
"The night I got home, there was no swelling or any bruising on her eye that had shown up. The doctors said that it would take 24 hours for bruising to develop," Kelly Hamilton said.
After family members reported the attack, doctors treated Ashley Hamilton for those bruises. She spent a birthday in the hospital.
Authorities are investigating the beating. Authorities say while Kelly Hamilton was out of town, Ashley stayed with family friends.
"We must be diligent in our efforts to find as much tangible evidence as possible since our victim in not in a position to tell us what happened to her. It is in the interest of justice to see that no stone is left unturned," said Gerald Johnson of the Rabun County Sheriff's Office.
Family members say they hope that investigation leads to an arrest for an attack on a woman who can't fight back.
"She's a beautiful little girl who can't defend herself and she's brutally beaten up here and I just want justice for her," said Kelly Hamilton.
Rabun County authorities say that they are gathering details in the case.
RELATED LINK: Prayers and Justice for Ashley Hamilton Facebook page
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HOME Jimmie Johnson Gear Jimmie Johnson Mens Jimmie Johnson Mens Sweatshirts (14 items) Product ID: 1121649
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Stay warm this season while showing support for Jimmie Johnson with this Checkered Flag hoodie. This comfortable pullover sweatshirt is decorated with Johnson's driver number and replica signature. It features ribbed cuffs and waistband to help keep the cold out.
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text: Love it, hate it, be confused by it... that's Microsoft's Excel program, which has been the industry standard for spreadsheets for awhile, and features calculation, graphing tools, and a macro-programming language. Carol DesJardins is a professor of computer information systems at St. Clair County Community College and has recently had the pleasure of co-authoring a college textbook on the subject. She says the program has proved to be a flexible application, despite its roots in statistical, engineering and financial sectors. DesJardins says she worked for about a year on the textbook, which helps students develop skills for the Microsoft spreadsheet software. The comprehensive edition is being published this fall.