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"PHA's research program has yielded an explosion of understanding about PH that was not known before."- John Newman, MD, Vanderbilt University Medical Center
"PHA's research program has yielded an explosion of understanding about PH that was not known before."- John Newman, MD, Vanderbilt University Medical Center
PH Treatments: What's on the Horizon
Watch Dr. Michael McGoon's webinar presentation from April 2013
Twenty years ago there were no pulmonary hypertension treatments available. Through focused research there are now twelve PH-specific treatments with more in development. But we know that your ultimate wish is for a cure, and that is why PHA will continue to support the work of researchers until the day when no one suffers from PH.
In just a little under a decade, PHA's Research Program has committed more than $14 million for PH research by leveraging partnerships with the National Heart, Lung, and Blood Institute (NHLBI) and the American Thoracic Society (ATS). We have supported over 49 promising researchers through four independently reviewed, cutting-edge research programs.
Read more about PHA's Research Program
PHA's Scientific Leadership Council's Education Committee has put together comprehensive factsheets on all the treatments available for pulmonary hypertension. Read more about current treatments
Every issue of PHA's quarterly print newsletter Pathlight features a Research Corner with information about some of the latest research. Read more
The American College of Chest Physicians (CHEST) recently released guidelines for the management and treatment of pulmonary arterial hypertension (PAH) in adults, Pharmacological Therapy for Pulmonary Arterial Hypertension in Adults: CHEST Guideline and Expert Panel Report, in the CHEST Journal. The guidelines are free to view for clinicians, and provide the latest and most accurate treatment guidelines for PAH. The Pulmonary Hypertension Association (PHA) endorses these guidelines and sees them as a step in the right direction. "Many times physicians are not clearly informed on the latest ways to treat PAH," said Rino Aldrighetti, PHA President and CEO. "These guidelines help physicians understand the broad range of therapies available and the need for more research to create more."The CHEST Guideline and Expert Panel Report provides 79 recommendations and expert consensus statements aimed at assisting physicians in the management of PAH using the latest drug therapies. The guidelines were reviewed and endorsed by the PHA Scientific Leadership Council. Read the guidelines
Health e Galaxy - Subcutaneous treprostinil improves outcomes in selected infants with severe pulmonary hypertension and chronic lung disease (CLD) of infancy that have not responded adequately to conservative therapies, researchers say. This is a report of one center's experience with an extremely small number of carefully selected patients.
One of the co-authors on this paper is Erika Berman-Rosenzweig, MD, a member of PHA's Board of Trustees and Scientific Leadership Council. Read article
Medical Xpress - In a groundbreaking study, researchers from Brigham and Women's Hospital (BWH) have identified a related family of molecules believed to be a major root cause of pulmonary hypertension, a deadly vascular disease with undefined origins. This is one of the first studies to leverage advanced computational network modeling to decipher the molecular secrets of this complex human disease.
The study is published online June 24, 2014 in The Journal of Clinical Investigation. The senior corresponding author, Stephen Y. Chan, MD, PhD, BWH Divisions of Cardiovascular Medicine and Network Medicine, was a 2010 recipient of PHA's K08 Supplemental Award. Read article
Reuters - Actelion Pharmaceuticals US, Inc. released today the initial, positive results from the Phase III GRIPHON study of selexipag in 1,156 patients with pulmonary arterial hypertension (PAH). Selexipag is the first non-prostacyclin analogue that acts as a stimulator for the prostaglandin receptor (IP). Read article
PHA's Scientific Leadership Council recently finalized their official fact sheet on macitentan (Opsumit®).
Read and download the new fact sheet
Participating in research & clinical trials helps provide information vital to progress toward a cure.
more about participating in research
Research grant opportunities are available from PHA's Research Program in the field of PH.
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Polishing off the Silver Conference, Ash heads toward his next challenge—the far-off Hoenn region! While he must say goodbye to old friends, he makes the acquaintance of May, a Trainer just starting out on her Pokémon journey. Along with her little brother Max and the ever-reliable Brock, this pack of Pokémon Trainers begin pursuing their dreams—with Ash racking up three Gym Badges, while May changes tack to follow the Contest path of a Pokémon Coordinator.
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Doom 4 Announcedid Software today announced that it has begun production on Doom 4, and is now in the process of expanding its internal team of developers to work on the shooter sequel.
"Doom is part of the id Software DNA and demands the greatest talent and brightest minds in the industry to bring the next installment of our flagship franchise to Earth," said id Software CEO Todd Hollenshead in a release.
"It's critical for id Software to have the best creative minds in-house to develop games that meet the standards synonymous with our titles."
The company is currently accepting applications to fill job openings covering roles such as producer, lead designer, and lead animator, among others.
The job listings page indicates that applicable platforms for the positions are PC, PlayStation 3 and Xbox 360. Though no further details on the game were released, the studio will likely make use of its new id Tech 5 engine for the project.
id Software lead artist Kevin Cloud recently told Shacknews that one of the strengths of the company's new engine is its cross-platform performance.
"You don't even have to worry about how it's going to look on PS3 or 360. Right now we've got it running cross-platform running 60 hertz, and it looks really good," said Cloud. "In terms of what artists are available to achieve--it's something you have to see for yourself. I can say this, but you still won't get it until you see it."
id will be hosting the 13th annual QuakeCon convention on July 31.
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Oh, I just saw your post...I hope she's okay!
I posted in new moms yesterday about Charlies horrible cough, and only got two responses...
Its like a raspy bark... Which makes me think Croup...
Now she is coughing so hard that its making her throw up... This has happened twice.
She does not have a fever... in fact her temp is slightly lower than normal.
Very congested, and seems to be having a little trouble breating... Not bad enough to where she stops, but very stuffy..
None of the walk-in clinics here are open on saturday.. I called the Pedi, but since she's not an established patient yet, all they could do is refer me to the ER. (which is where the on-call doctor is anyways)
Should I take her to the ER?
OH no! I think I would take her in. Hope she'll be ok.
Aww yeah, I would take her in. I also looked in the other thread and saw her respiratory rate. It is high.
Average respiratory rates, by age:
* Newborns: Average 44 breaths per minute
* Infants: 20–40 breaths per minute
* Preschool children: 20–30 breaths per minute
* Older children: 16–25 breaths per minute
* Adults: 12–20 breaths per minute
* Adults during strenuous exercise 35–45 breaths per minute
* Athletes' peak 60–70 breaths per minute
Ashley, I hope Charlie gets better soon!
I confess I've been slacking about posting here. It's been a hard week for me, between ongoing illness and work stress and pottytraining and car break-ins and dh. And after I mentioned how it was so nice for dh to listen to me about discipline issues, last night he tried to put ds in time out for not listening to him when he asked him to pull his pants up. I sent him two articles on dealing with toddler defiance and saying no after that. I was pretty much on the verge of tears all day yesterday, but I attribute to a hard week and pg. hormones.
Last night I was attending to a crying child in the middle of the night and stepped away from the bed to get a spare binky and dh came in because the crying was still ongoing and I guess he didn't know I was already in there. I was returning to the side of the bed when dh turned quickly to get a binky himself. BANG! His brow collided with my brow and I saw a bright flash of light and I collapsed to the floor, whimpering. It hurt so badly! If I'd been watching it, though, I think I might have laughed. We must have looked pretty comical.
It's been a rollercoaster. The first two days were awful, then they did really well, then they got sick and backslid. And then Claire started holding everything because she didn't want to go on the potty and had a couple of very painful bms which reinforced her fear. And then the past couple of days it's been really good again, like 0-2 accidents a day total. Still, going out has been... challenging. I had to run with them back to the car 3x within 30 minutes the other day at the park, which resulted in screaming from the twin who wanted to keep playing and one accident.
This is so much work! I'd never be able to do this with a newborn in the house.
Oh, oh, and I just remembered something else I wanted to share.
The other morning, dh and I woke up and he told me about this dream he'd had, about racing submersibles through blue canals on an exotic planet. He described the pinnacles towering above him and how he could duck underwater to avoid a ledge. Then he asked me what I dreamed about. I told him I'd spent half the night as an assistant manager at a grocery store, and described the mundane problems I had to solve. He's been laughing at me for having such boring dreams.
Dh has really incredible dreams, all night, every night. No wonder he spends so much time sleeping--so would I.
Well here is my current most played on iTunes.
Runaway Train-Soul Asylum
Disarm-Smashing Pumpkins
Fireflies-Owl City
Very Busy People-The Limousines
Lifeline-Papa Roach
One Song Glory-Rent
Paparazzi-lady Gaga
Savior-Rise Against
Wishing Well-Airbone Toxic Event
Mad World-Lambert
Sweet Dreams-Beyonce
Show Me what I'm looking for-Carolina Liar
Don't Stop-Innerparty System
In This City-Iglu and hartley
Return to Innocence-Engima
Rooftops-Lost Prophets
One Day-Matisyahu
Fly on the wall-Miley Cyrus
Last edited by Cosmosmom; 01-16-2010 at 03:53 PM.
You have some good songs too Cosmosmom
Wow Lydia.
DH has very vivid dreams too, but he doesn't like to sleep! He says it's a waste of time.
I have weird dreams...they're usually about people I haven't thought about in years, or I'll have a sexual dream about someone I never thought of in that way and it seems so real and I have no idea where it comes from. Actually if I may bring up Joey again...the weirdest thing happened the night I came home from the concert. I was dreaming about him, and something woke me up. I was bummed and I decided to try to dream about him when I fell asleep again. When I fell asleep I did dream about him again! That never worked for me before, but I'm sure glad it worked that time
atenielle I hope Charlie is doing okay...update us when you can.
I'm glad the PTing is going okay (Lydia), even if it is up and down. You can do it!
Sorry I didn't come update.. We spent 7 hours in the ER last night, and by the time we got home I was just ready to pass out!
The nurses also thought it was croup, and I figured there wouldn't be much they could do for us. Then the doctor came in, and listened to her breathe and ordered a chest x-ray.
Im extremely glad we went in, because it turned out to be pneumonia, and bronchiolitis.
She got two breathing treatments, and oral steroid, and antibiotics.
Ashley, I'm so glad you brought her in!
Is she doing better now?
Me (40) DH (47) & furbabies * m/c 7/08 4/12 11/12
I confess that I woke up at 4:50am and felt like screaming. I was sleeping crappy all night, dreaming of baby stuff, waking up constantly and tossing and turning because I couldn't get comfortable. THEN at 4:45, Jimi farted the loudest and stinkiest fart I have ever experienced in my life and that's when I finally said "FORGET IT, I'm getting out of this stinky room!!!" I came downstairs and ended up falling back asleep around 6:30 on the couch. I don't think I've had a good nights rest in a month or more.
So sorry, Janeen! I admit I get mad at DH for late-night stinky farts, too.
Me (40) DH (47) & furbabies * m/c 7/08 4/12 11/12
These suckers are so loud they wake us both up!! I would say it has happened twice in the last 3-5 nights. I mean LOUD, like a bomb is going off in our bedroom and the dude jerks enough to shake the bed as he's doing it like he's pushing HARD to get that bad boy out! Ugh.
Me (40) DH (47) & furbabies * m/c 7/08 4/12 11/12
I confess that I have felt less than interested in being a mom for the past couple of weeks. I am bored with playdough and baby dolls. I want to work on my art. I need to get over it.
"Any idiot can face a crisis; it is this day-to-day living that wears you out." -Anton Chekhov


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Thinkproducts puts its money where its food is: the company donates up to $250,000 per year to the following organizations that are working to find a cure for many of today's epidemics - the California diabetes foundation; the university of Southern California childhood obesity research center; autism research institute in san Diego, California; the William k. Warren celiac center at the university of California; and the Susan G. Komen fund for breast cancer research.
Availability: Usually Ships Within 24-48 Hours
Think Products - thinkThin Protein Bar Brownie Crunch - 2.1 oz (60g)
Think Products thinkThin Protein Brownie Crunch provides a burst of clean energy, a moment of relaxation, and satisfaction for those in need of taste and sustenance. Think Products all natural, high protein thinkThin bars deliver 20 grams of protein. Draped in rich delicious chocolate, this great tasting thinkThin bar has only 2 effective net carbs. Rated one of the top bars in the natural industry, thinkThin was developed as an inner beauty food designed for those who think about what they eat.thinkThin bars deliver strength, beauty, energy, and vitality. thinkThin bars also appeal to consumers with special dietary needs because they are gluten free and sugar free and offer diabetics an alternative healthy snack.
Non-GMOthinkThin is comitted to sourcing ingredients that are not genetically engineered in all of their products. They have stringent protocols for GMOs which includes requiring affidavits from ingredient suppliers demonstrating they can meet their non-GMO requirements. thinkThin sources non-GMO soy protein isolate.
Living Gluten FreeMany people choose a gluten free lifestyle but for those who have been diagnosed with gluten intolerance or celiac disease, living gluten free is essential. It is estimated that 31 million Americans are affected by celiac disease and related conditions.thinkThin founder Lizanne Falsetto eliminated gluten during her 20's simply because she realized that she didn't feel good when she ate certain foods. A few years ago, her daughter was actually diagnosed with gluten sensitivity.Since inception, thinkThin protein bars have been gluten free, without compromise to taste or quality. thinkThin is delighted to deliver delicious, nutritious snacks and gluten free bars for all foodies on the go, including those who live gluten free! Eat up!
Are all of their bars sugar free? Their thinkThin Protein and thinkThin Bites lines have 0g sugar. Their thinkThin Crunch and their thinkThin Crunch Fruit & Nut lines do contain a controlled level of sugar at 3-8g. Can diabetics eat their thinkThin bars?They always recommend consulting your physician first. Their thinkThin and thinkThin Bites lines do not contain sugar and are suitable for consumers controlling their sugar intake. Do thinkThin bars contain caffeine?Most of their thinkThin bars contain less than 2 mg per serving of caffeine. Their Chocolate Espresso flavor does contain approximately 20 mg of caffeine from the coffee in the bar. Their Mixed Nuts Crunch bar is caffeine-free because it does not contain chocolate or any other caffeine containing ingredient.
Are their bars gluten free?All of their products are gluten free.
Are any of their bars free of chocolate? Their thinkThin Crunch Mixed Nuts bar does not contain chocolate.Are their bars certified kosher? All thinkThin bars are now kosher certified regular dairy by Kehilla Kosher. Are their products vegan? Most of their products contain dairy and are not vegan. Their thinkThin Crunch Mixed Nut bar does not contain dairy, but does have honey to hold the bar together. All three flavors of thinkThin Crunch Fruit & Nut are vegan. What are the "other carbs" listed in the nutrition facts panel?Other carbs consist of ingredients that are not included in the sugar alcohol, sugar and fiber content but are included in the total carb amount. An example of an "other carb" in their bars is glycerin.
Are any of their bars dairy-free?None of their thinkThin Crunch Fruit & Nut bars contain dairy. Their thinkThin Crunch Mixed Nuts bar is dairy free as well.What are Net Carbs? How do you figure them out on their facts panel?They make it easier for you to calculate the net carbs in their bars. Their nutrition facts panel identify the breakdown of total carbs including dietary fiber, sugars, sugar alcohols and other carbs. The net carbs in thinkThin are calculated by subtracting the non-effective ingredients from the total carbs. Examples of the non-effective ingredients include: sugar alcohol (maltitol), glycerin (carbs), and fiber. Can maltitol result in gastrointestinal issues or discomfort?Popular sugar alcohol sweeteners include maltitol. Maltitol sweeteners are made through a fermentation process of corn or sugar cane. They contain fewer calories than sweeteners like pure sugar and honey. Sensitivity to maltitol is individual. What is glycerin and what is it derived from?The glycerin they use is derived from plant sources. It is used as a humectant (an ingredient used to preserve the moisture content of the bar) and helps to maintain a soft texture in the core of the bars. Back to Top
Why do some of their bars contain palm kernel oil?Only their thinkThin bars coated in dark chocolate contain palm kernel oil. Their thinkThin Protein bars are sugar free, and there are currently no sugar free dark chocolate coatings without palm kernel oil available. Palm kernel oil allows for a delicious, chocolatey coating that remains solid at room temperature
Natural Portable NutritionthinkThin products provide natural and delicious portable nutrition to support the health and well-being of busy, active people who care about what they eat. All thinkThin natural snack bars are based on three nutritional principles: no refined sugar, a good source of protein and gluten free.
Healthy Energy & Natural Weight ManagementthinkThin products contain uncompromised quality ingredients that are a good source of protein, have no refined sugar and are gluten free to provide an excellent source of energy without the punishing side effects of gluten and refined sugar. Their entire product line builds upon this delicious foundation while delivering a more premium nutritional profile than any weight management offering on the market. thinkThin's protein bar is the No. 1 ranked natural weight management bar in America (SPINSscan research).
Weight WellnessAt thinkThin, they believe strongly in the premise of weight wellness. This is the optimal weight range at which our bodies feel happy and healthy. This is not defined or dictated by aesthetic, shape, weight or tape measure - it is the physical and emotional outcome of feeling good, energized, funny, confident, and living a life filled with joy and laughter. Once we focus on being active, healthy and happy, our bodies will follow and align.
thinkThin: What's in a Name?thinkThin products are stripped down to provide only the highest quality ingredients. In the spirit of "packing light" - one bar goes a long way - in your bag, in your car and in your pocket. When you take thinkThin with you, you are good to go with a nutritious boost for anytime of day without the punishing side effects of refined sugar and gluten. They believe that attitude is everything and when we all start living with the thoughtful intention of health and energy, our bodies will follow.
Other Ingredients: Protein Blend (Whey Protein Isolate, Calcium Caseinate, Soy Protein Isolate, Casein), Glycerin, Maltitol, Coating Caseinate, Milk Fat, Soy Lecithin, Natural Flavors, Salt), Alkalized Cocoa, Almonds, Water, Soy Crisps (Soy Protein Isolate, Rice Flour, Salt), Canola Oil, Soy Lecithin, Chocolate, Sea Salt, Natural Flavors.
Contains: Milk, Soy, Almonds.Manufactured in a plant that also processes Eggs, Peanuts and Tree Nuts.
Gluten Free
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Spiritual Living & Spiritual Guidance
In today's hectic world, sometimes you have to stop and recover from everyday stress with a little spiritual guidance. We can offer you a multitude of great spiritual living guides, from many schools of thought, courtesy of some of the world's finest thinkers. At Gaiam, we look forward to helping you start your journey to enlightenment.
Our guided meditation Conscious Journey CDs help you relax from a hard day's work with visualization exercises, breathing exercises, and audio tracks to help you cleanse your energy pathways and be more alert and focused. We also offer soundtrack CDs of ambient natural sounds or peaceful New Age music free of distracting lyrics.
If you yearn to learn from the ancient spiritual practices of Buddhism, Taoism, or Hinduism, our Eastern Practices category will provide you with ineffable wisdom from Confucius, Laozi, and many of the other great sages of history. As well as benefiting from their wisdom, you can learn about mindful stress-relieving practices such as yoga and qigong.
Our selection of documentaries explores the roots of spiritual traditions and examines some concepts, such as the chakras, scientifically. Alternatively, you can indulge your sense of mystery by learning about ancient prophecies or challenge your notions of life and death by exploring the world of ghosts and spirits.
If you want to get a feel for how the world works today, you'll want to look at our World Knowledge category. You can familiarize yourself with scientific concepts and explore how they connect to the spiritual, or learn more about currently accepted theories. Learning about the mysteries behind historical landmarks is another possibility.
Exploring a new way of spiritual living with our line of CDs could broaden your mental horizons farther than you can imagine. You can expand your knowledge outward or look inward by seeking spiritual guidance with our wide selection of products, helping you to grow on your journey to a better you.


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Attorneys for Lon Morris College, along with the Texas Attorney General's Office, are investigating endowment funds that have gone missing from the bankrupt East Texas college.
The college's attorney filed a motion in court last month requesting to interview former college president Dr. Miles McCall and accountants at Acker and Co. in relation to missing funds related to an endowment.
Attorneys examined McCall this week. He resigned from the college back in May.
They are expected to interview Lynn Acker and representatives of Acker & Co. under oath about the missing funds. The college also asked for all documents related to the Long Endowment including board minutes, resolutions and e-mails.
Attorneys could not disclose more details about the investigation.
Paperwork filed in federal bankruptcy court said the attorneys are seeking information about a $1 million Long Endowment. That endowment was left from the will of LMC grad and Rusk-native Dr. James Long (1925-2009). Long graduated from Lon Morris College, went on to earn his B.S. and M.A. from Sam Houston Teachers College in Huntsville and Ph.D. in Zoology at the University of Texas at Austin.
In documents submitted to bankruptcy court in July 2012, the Long Endowment had a balance of $1,092,796.
Dr. Long's will submitted to the court states that if Lon Morris College is unable to accept the endowment or ceases to exist at any time, the money should be given to Sam Houston State University. LMC has not held classes since the Spring 2012 Semester.
It is still not known what has come out of those sworn oral examinations or where the endowment money may be located. Attorneys say the investigation is still ongoing.
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Celebrate one half of the Lyoto Machida's legacy with symbols from his Japanese culture!
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Comments about Venum Lyoto Machida Torii Legacy Fight Shorts:
Loose stitches and wears easily
Bottom Line No, I would not recommend this to a friend
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A roundup of the stories you missed while you were sleeping.
Police deliver pie after Pizza Hut driver hurt
PORTLAND, Ore. (AP) — After a pizza delivery driver was injured in a crash in Portland, Oregon, two police officers completed the delivery for him. Full Story
(Butch Comegys/AP)
Filmmaker: Ambush suspect was odd but not a threat
Eric Frein obsessively collected military memorabilia, dismissed his fellow war re-enactors as dilettantes, and took his hobby so seriously that he spoke French during a simulated Vietnam War-era interrogation, according to a filmmaker who interviewed the man now suspected of ambushing a Pennsylvania State Police barracks. Full Story
Emma Watson targeted by nude-photo hacker?
Messageboard 4chan user starts countdown timer, hinting that the actress will be the next celeb victim of leaked racy photos.


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The movie, Rain Man , ruined Autism for autistics.
Kim Peek, who was the inspiration of Dustin Hoffman's performance, was truly rare. He was an autistic savant who who remembered details in over 12,000 books he had read. He could read two pages of a book, at once. One page with each eye. His ability to recall facts and figures was unparalleled.
This is not a 'gift' that every autistic is given. Yet, sometimes I'm asked, "So your son is like Rain Man?"
When parents of autistic children gather, they will ask, "So, what is your child's thing?" Which is our verbal short hand for, "What topic is your child fascinated by?" Some autistic children will be experts on dinosaurs, trains, sports or other topics. They dedicate themselves to learning everything they can on a topic that they become obsessed with. They will can talk, at length, about their favorite subject with a level of confidence and authority that is truly staggering.
My son, Alex, has a very hard time speaking. He has reduced sensation in his mouth, so forming words can be difficult. He has gotten much better, with the in home therapy and speech therapy he receives in school. That is part of the reason why I don't really know if he has a 'thing'. Ironically, his thing may be languages. He can speak some words and write sentences in foreign languages.
He wrote creyones on his dry erase board. I wasn't sure if he had misspelled something and just left it on his board. It took me a few weeks to realize that he had written crayons in Spanish. He has asked his school aid for an apple in French, by typing it on a computer. He also knows some sign language, which we use to help in his comprehension of things my ex-wife and I ask or tell him. (My ex-wife has deaf parents and is fluent in sign language. I can 'speak' sign at a 1st grade level, on a good day.) Him knowing some sign language helps him connect with his grand parents. Which is a very good thing. That said, I still wouldn't classify those as savant skills.
He is rare in his own way.
He has the ability to read body language. I can make 'the Dad face' and he knows that he's doing something he shouldn't be doing.
He is very affectionate and loves to get and give hugs.
He has a sense of humor and loves to laugh.
Some autistics never gain these skills.
The bottom line is, every person with Autism is unique, in their own way. They cannot be defined by a character that was in a movie from 1988. You cannot lump them into a group of defined behaviors. Just like any neuro-typical person, they have their own personalities. You need to get to know them to understand them. Just like anyone else.


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ABSTRACT: Recent legal actions and policies aimed at protecting the fetus as an entity separate from the woman have challenged the rights of pregnant women to make decisions about medical interventio...
November 2005
American Congress of Obstetricians and Gynecologists
409 12th Street SW, Washington, DC 20024-2188 | Mailing Address: PO Box 70620, Washington, DC 20024-9998
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When I need tea, I drink rooibos. It has no caffeine nor tannins. See here and here.
My question is: are any of these chemicals a diuretic? My husband insists that even decaffeinated or herbal tea makes him 'go' more often; he blames the tannins for that. Does that make sense?
[ I'm a hopeless babe w/r/t tea. It is a disfavored drink in my house, hence, I've allocated very few brain cells to its understanding. ]
Thanks for any guidance.


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South Bend police need your help finding out who robbed a pair of 7-Eleven stores early Thursday morning.
The first incident happened around 1:45 on East LaSalle Street. Approximately 36 minutes later the 7-Eleven on Lincolnway West was also robbed.
Dispatchers could not disclose much information on the robberies. They say don't know if the robberies are related but they did occur only 3.4 miles apart.
We're unaware of an injuries associated with the robberies.
WSJV-TV FOX 2858096 County Road 7, SouthElkhart, IN 46517
Switchboard: 574.679.9758News Phone: 574.679.4545Station Fax: 574.294.1267Email: email@example.com


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Adventures in Amsterdam (Part II)
By johndotcom
We hit the ground running yesterday and before I even knew what was happening I was staring at some of the most amazing pieces of classical art in the world! Danny [Dringenberg] knows more about Amsterdam than most Dutch people… It blows my mind! Dan said, "You wanna go see the Rembrandts, bro?" I didn't even know they were here… So let's go to the Rijks Museum and check it out… [Part I]
I was impressed with Rijks and I would suggest checking it out when you come to Amsterdam… There are other museums here, weird… But the Tattoo Museum is the coolest! Ha-ha!
After the Rijks we went back to the Tattican to meet Hanky Panky and his wife Louise and the rest of the ATM family for dinner. I was able to take some more pictures while I was waiting and I was just shocked at how much stuff I had not seen from the previous day.
I probably took about 300 pictures yesterday… You can check out this slideshow to see more pictures from the Tattoo Museum…
We all had a really fun and tasty meal at a Chinese spot (Happy Corner) down the street from the museum. Everyone was in attendance including Henk's dogs! Apparently in Amsterdam it is commonplace to bring your dog(s) with you everywhere! Even a 100 pound white German Shepard…
Some of us drank and walked around the city, window shopping in the Red Light District… It's so surreal. I never want to leave…Tips for Amsterdam:
- Be prepared to walk everywhere
- Bring a raincoat
- Red Lights good… Blue Lights bad!
Adventures in Amsterdam (Part I)
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Interim DSMB Named for National Lung Screening Trial
An interim Data and Safety Monitoring Board (DSMB) has been appointed for the 50,000-participant National Lung Screening Trial (NLST), following the resignation of the trial's original DSMB on March 26. The DSMB Chair, Dr. Sylvan Green, Arizona Cancer Center, explained that the board was resigning because individual members do not have liability insurance coverage as part of the professional services contract under which they were secured for the trial.In response, officials from NCI (which is sponsoring the trial) and the National Institutes of Health (NIH) are working together to resolve this issue and quickly appointed an interim DSMB. The interim board is composed of NIH scientists with appropriate clinical and research expertise.
NCI policies require that all clinical trials that the institute sponsors have a DSMB. The activities of DSMBs are distinct from those performed by IRBs, which review and approve research protocols for clinical trials prior to their launch. Both IRBs and DSMBs, however, play critical roles in ensuring patient safety.Read more
A Strong Foundation for Progress Against Cancer
The news last week was replete with excellent research presented at the American Association for Cancer Research (AACR) annual meeting in Orlando. Meetings like this energize the cancer community, bringing together some of the most brilliant and dedicated researchers to share insights, educate the next generation of investigators, and celebrate progress.
At the AACR meeting, I had the privilege to give an address about the opportunities we now have to make unprecedented advances in the prevention, diagnosis and early detection, and treatment of cancer. This talk came just a few weeks after the publication in Fortune magazine of an in-depth article - written by a cancer survivor - that addressed the state of cancer research in the United States.Read more
Interim DSMB Named for National Lung Screening Trial
An interim Data and Safety Monitoring Board (DSMB) has been appointed for the 50,000-participant National Lung Screening Trial (NLST), following the resignation of the trial's original DSMB on March 26. The DSMB Chair, Dr. Sylvan Green, Arizona Cancer Center, explained that the board was resigning because individual members do not have liability insurance coverage as part of the professional services contract under which they were secured for the trial.
In response, officials from NCI (which is sponsoring the trial) and the National Institutes of Health (NIH) are working together to resolve this issue and quickly appointed an interim DSMB. The interim board is composed of NIH scientists with appropriate clinical and research expertise.
NCI policies require that all clinical trials that the institute sponsors have a DSMB. The activities of DSMBs are distinct from those performed by IRBs, which review and approve research protocols for clinical trials prior to their launch. Both IRBs and DSMBs, however, play critical roles in ensuring patient safety.
A DSMB is intimately familiar with a trial's protocol and its plans for monitoring patient safety and data collection. The board's central function is to review interim analyses of outcome data and cumulative toxicity data summaries. Based on these reviews, the board determines whether the trial should continue as originally designed, be amended, or possibly even be terminated. The board may also recommend other actions based on these reviews.
For example, as recently reported (NCI Cancer Bulletin, March 16), the DSMB of a phase III clinical trial comparing five years of adjuvant chemotherapy for breast cancer using either tamoxifen alone or switching after several years to the aromatase inhibitor exemestane recommended that results data be released before the trial was complete because of the significant benefit seen in overall survival in patients treated with exemestane. The need for liability indemnification for such consultation and advice is a question that is now being addressed.
Launched in 2002, NLST is the largest trial of CT screening for lung cancer. A randomized, controlled trial, NLST is comparing spiral computed tomography and standard chest X-ray for the early detection of lung cancer. Nearly 50,000 current or former smokers have enrolled in NLST at more than 30 study sites across the country. As of February 2004, the trial reached full enrollment in record time and is closed to further enrollment. Nothing affecting patients, patient safety, or data collection has changed; the focus of the trial and its outcome have not been altered.
Further details on this development will be reported as they become available. For more information on NCI and NIH policies on data and safety monitoring of clinical trials, visit http://deainfo.nci.nih.gov/grantspolicies/datasafety.htm (NCI) and http://grants.nih.gov/grants/guide/notice-files/not98-084.html (NIH).
A Strong Foundation for Progress Against Cancer
The news last week was replete with excellent research presented at the American Association for Cancer Research (AACR) annual meeting in Orlando. Meetings like this energize the cancer community, bringing together some of the most brilliant and dedicated researchers to share insights, educate the next generation of investigators, and celebrate progress.
At the AACR meeting, I had the privilege to give an address about the opportunities we now have to make unprecedented advances in the prevention, diagnosis and early detection, and treatment of cancer. This talk came just a few weeks after the publication in Fortune magazine of an in-depth article - written by a cancer survivor - that addressed the state of cancer research in the United States.
Of course, not every story has a positive angle - nor should it. The title of the Fortune article was "Why We are Losing the War on Cancer (And How to Win It)" and it raised some important criticisms about how cancer research has been conducted. In my address at the AACR meeting, I discussed a number of strategic initiatives I believe, when taken up with the Fortune piece, address many of these criticisms.
And I believe that, with the initiatives and priorities we have established, we can fulfill our mission and reach the 2015 goal of eliminating suffering and death due to cancer. Take, for example, mouse models. We have shifted our focus away from xenograft models to the exciting work being done today with genetically engineered mouse models, much of which is being coordinated via the NCI Mouse Models of Human Cancers Consortium. These mouse models - which have physiologic properties far more reminiscent of human biology and can recapitulate human cancer both in terms of molecular biology and disease progression - are already generating important advances. For instance, an entire class of drugs, HDAC inhibitors, has been developed using an engineered mouse model of leukemia. With this highly powerful model, we will continue to make important new findings that I believe can be quickly translated into human clinical trials.
We are also making important changes to how clinical trials are conducted. At NCI, we are developing a national infrastructure for cancer clinical trials and will provide national leadership to guide and oversee the effort. I believe that this will serve to accelerate the development and testing of effective interventions and ensure that those interventions are efficiently and seamlessly incorporated into standards of care.
And, finally, I believe we can achieve the 2015 goal because the cancer community has proven time and again to be a marketplace of grand ideas and, more importantly, earnest, collaborative action. Whether it's the use of proteomics and nanotechnology to improve strategies for detecting cancer at its earliest stages or investigating novel methods for eliminating disparities in care, the cancer community is clearly a hotbed of innovation.
At AACR, Dr. Leland Hartwell, president and director of the Fred Hutchinson Cancer Research Center and Nobel Laureate, gave the Distinguished Lecture, focusing on the potential of molecular diagnostics to improve cancer survival. If we can make the sort of organizational and cultural changes already under way, as well as continued advances in areas like early diagnosis and combination therapy, among others, Dr. Hartwell said, he is cautiously optimistic that we can achieve the 2015 challenge goal.
I wholeheartedly agree. Swift progress in these areas can and will happen. And cancer, no doubt, will continue to make headlines - headlines that document every advance and tell the story of how we will achieve such a remarkable goal of eliminating the suffering and death due to cancer.
Dr. Andrew C. von Eschenbach
Specialized Programs of Research Excellence: Moving Basic Research Discoveries into the Clinic
Since 1992, NCI's Specialized Programs of Research Excellence (SPOREs) have been instrumental in defining and culturing the field of translational research. The program's success results primarily from multidisciplinary teams of basic and applied researchers working together to move basic research discoveries into the clinic or, conversely, to determine the underlying mechanism of a clinical observation. As such, SPOREs have changed an important aspect of the cancer research model by breaking down communication barriers between investigators with diverse areas of expertise and focusing their collective attention on a single or related group of cancer sites. The overall program goal is to direct basic scientific discoveries toward human applications that have the potential to affect the prevention, detection, diagnosis, prognosis, or treatment of cancer in a particular organ site.
The SPORE program was conceived and implemented through a special $20 million appropriation from Congress in fiscal year 1992, representing a strategic response to the rapid expansion of cancer information being developed through basic research. At the time, no NCI funding mechanism focused exclusively on translational research; the SPORE program began as an experiment to promote interactions between basic and applied scientists and provide them with the flexibility to rapidly test new ideas and approaches.
Over the past 12 years, the program has grown from four organ sites to 14 and currently includes 56 SPOREs in breast, prostate, lung, gastrointestinal, ovarian, genitourinary, skin, brain, head and neck, lymphoma, leukemia, myeloma, pancreatic, and gynecological cancers. Unique features of SPOREs include their flexibility to change research direction to capitalize upon new translational opportunities, as well as their close ties to the patient advocate community.
Beginning in 2000, more emphasis has been placed upon the SPOREs to interact within and across organ sites. The SPORE network provides an excellent opportunity for cross-fertilization between different disciplines and enables translational goals to be quickly realized. Inter-SPORE activities are supported by administrative supplements to parent SPORE awards and are aimed largely toward the performance of early-phase clinical trials or biomarker validation studies. Many of these studies involve collaborations with other NCI networks, like the Cancer Genetics Network, the Cooperative Groups, and the NCI Intramural program. SPORE is also one of the first NCI programs to establish a public-private partnership with an outside funding organization. Specifically, the Avon Foundation has committed $20 million in support of administrative supplements for early-phase clinical interventions in breast cancer. The Avon-NCI Progress for Patients (PFP) Awards program was piloted within SPORE in 2002 and opened up to SPOREs and NCI-designated Cancer Centers in 2003. Currently, 21 early-phase clinical interventions in breast cancer are supported by the Avon-NCI PFP program, several of which represent inter-SPORE collaborations.
Most recently, two working groups have begun to systematically assess the pipeline of biomarkers and therapeutic agents being developed within the SPOREs. In January and February of this year, the working groups identified 10 to 12 priority projects with high potential impact within or across organ sites. The programs were struggling to overcome one or more different barriers ranging from acquiring enough material to perform a clinical trial to unraveling a complex series of intellectual property and regulatory issues surrounding the development of a panel of promising biomarkers. Interestingly, the solutions to some of these impediments may not require the expenditure of more funds, just some additional teamwork between individuals with diverse expertise, the original premise upon which the SPORE program was built.
In sum, the SPORE program represents one of NCI's many strategic opportunities to move basic discoveries into clinical applications.
Senate Appropriations Hearing for NIH FY 2005
The Senate Appropriations Subcommittee on Labor, Health and Human Services, and Education held a hearing on April 1 to focus on fiscal year 2005 funding for NIH. NIH director Dr. Elias Zerhouni, accompanied by all institute and center directors, talked about key research advances of the last year by NIH-funded researchers and gave examples of how the NIH Roadmap effort will shape patient-oriented research in the future.
Sen. Ted Stevens (R-Alaska) complimented Dr. Andrew C. von Eschenbach on a recent talk on imaging and inquired about the early end of the Prostate Cancer Prevention Trial to study the drug finasteride. Dr. von Eschenbach emphasized that this trial demonstrated a protective effect for prostate cancer and was ended because the clinical end points were met early. The trial has led to another clinical study of the drug's impact on disease virulence.
Senators expressed concern about NIH's reduction of inflationary increases for grantees in subsequent years from 3 to 1.9 percent and wanted to know how this change in a long-standing NIH commitment would affect researchers and the number of new grants funded. Senators asked Dr. Zerhouni to provide more specific information about how budget projections for fiscal year 2006 will have an impact on NIH initiatives.
Institute directors received questions on a number of issues, including research on obesity, complementary and alternative medicine, new technologies, stem cell research, bio-defense, neurodegenerative diseases, kidney disease, macular degeneration, and autism.
Senators Tom Harkin (D-Iowa) and Arlen Specter (R-Pa.) continued to return to the issue of stem cell lines and whether the currently available cell lines would be enough for investigators to study and whether these cell lines would be adequate for use in humans. The senators requested a comprehensive report on the "state of the art" of stem cell research to assist the subcommittee in policymaking.
Hearing on HPV and Cervical Cancer
The House Government Reform Subcommittee on Criminal Justice, Drug Policy and Human Resources held a hearing on human papillomavirus (HPV) and cervical cancer on March 11. The purpose of the hearing was to examine the latest medical science regarding cervical cancer and ongoing federal efforts to treat the disease and prevent HPV infection.
Dr. Ted Trimble, of NCI's Cancer Therapy Evaluation Program, discussed the pathology and progression of HPV infection and its relation to cervical cancer and commented on current studies on vaccine development. Witnesses from the Centers for Disease Control and Prevention and the Food and Drug Administration described their activities in HPV/cervical cancer surveillance and prevention and in labeling options for condom use. Abstinence education was also discussed as well as the failure of condoms to protect against HPV infection.
Chemoprevention Study of Selenium for Non-Small Cell Lung Cancer
Name of the Trial
Principal Investigators
Why Is This Trial Important?
Researchers are investigating selenium as a chemoprevention agent against development of secondary lung tumors. "With stage 1 non-small cell lung cancers that have been treated successfully with surgery, the more likely risk is development of a second tumor rather than recurrence of the original tumor," said Dr. Karp. "So we are interested in seeing if selenium will be effective in preventing the growth of new tumors in patients who have undergone curative surgery for non-small cell lung cancer."
In a previous study, selenium appeared to cause decreases in both prostate and lung cancer, but those results were not statistically validated. Subsequent studies, including this one, seek to validate those observations," Dr. Karp said.
Who Can Join This Trial?
Where Is This Trial Taking Place?
Who to Contact
An archive of "Featured Clinical Trial" columns is available at http://cancer.gov/clinicaltrials/ft-all-featured-trials.
Three Top NCI Positions Filled
NCI Director Dr. Andrew C. von Eschenbach recently announced three new appointments - a new director for the Division of Cancer Treatment and Diagnosis (DCTD) and two new deputy directors within his office.
As the new DCTD director, Dr. James H. Doroshow fills a position vacant since 2001. He comes to NCI from Los Angeles, where for 20 years he served as both chair of the Department of Medical Oncology and Therapeutics Research and as associate director for clinical research at the City of Hope Comprehensive Cancer Center. In addition to his division responsibilities, Dr. Doroshow will lead NCI's Clinical Trials Working Group.
In the director's office, Dr. Karen Antman will lead strategic scientific efforts in her new role as deputy director for Translational and Clinical Sciences. She will direct a broad national research program that includes the Cancer Centers Program, the Specialized Programs of Research Excellence, and other translational programs. Dr. Antman had been director of the Columbia University's Herbert Irving Comprehensive Cancer Center and chief of the Division of Medical Oncology.
As reported in the Feb. 10 NCI Cancer Bulletin, Dr. Mark Clanton was recently named the new deputy director for Cancer Care and Delivery Systems at NCI. With a strong background in managed care and health plan administration, Dr. Clanton will bring his expertise to bear on expanding and enhancing NCI's research portfolio to have a greater impact on cancer care delivery.
Telephone Education Workshop on Cancer Survivorship
NCI Director Receives Cancer Public Service Award
Other awards from the GW Cancer Institute included the Cancer Advocacy Achievement Award to Dr. Ellen Sigal, Chair, Friends of Cancer Research; the Cancer Compassion Award to Zora Brown, Founder and Chair of the Cancer Awareness Program Services and Breast Cancer Resource Committee; and the Celebration of Life Award to Lance Armstrong, Tour de France champion and founder of the Lance Armstrong Foundation.
Constance Percy Dies at 89
Basic Science Leads the Charge in the War on Cancer
In an article in a recent edition of Fortune magazine, Clifton Leaf, a cancer survivor, assesses the state of the war on cancer and concludes that we are losing. Moreover, he proposes a game plan for winning it. Is he right? In many ways, yes, he is right. He argues that we should focus on cancer as a process and fight it at its earliest stages when it is highly curable rather than at later stages where battle after battle has failed. He argues that drugs should be tested on patients earlier in the cancer process rather than on patients who have failed to respond to all other treatments, as is currently done. He argues that cancer, like AIDS, will require multiple drugs and that we need to test multiple drugs in combination, some of which may have no efficacy in isolation. While I agree with each of these recommendations, he fails to note that they are only now becoming possible and that these new opportunities derive from the very source he denigrates: fundamental knowledge provided by basic science.
Consider each of his points above in turn. There is currently no technology able to examine comprehensively all of the molecules in the blood for early diagnosis of disease. This means that it will be necessary to focus molecular diagnosis on molecules known to be abundant in tumors or involved in tumor processes. This knowledge is coming from basic research in cancer. It may well be productive to test new drugs in patients with earlier stages of cancer and to test new drugs in combinations, although both approaches would face ethical and regulatory hurdles. If either can be accomplished, that would not be done without excellent information suggesting potential efficacy. That information would come from drug target validation in human cells, a technology dependent on small RNA molecules, only discovered in the last couple of years as a result of basic research. It is definitely too soon to throw out basic science!
NCI Director Andrew C. von Eschenbach has called for the cancer community to eliminate the suffering and death from cancer by the year 2015. Given the poor state of progress toward it to date, one must ask: Is this possible? What is important about this challenge is not the precise date but the sense of urgency, the same sense of urgency expressed by Mr. Leaf. As a cancer center director, I have experienced the sense of urgency of our patients, donors, and board members. People who support cancer research and experience cancer in their families expect us to focus on eliminating this disease now. I think they are all correct in thinking that a more effective approach is possible and should be applied post haste. I believe the answer is in methods to detect cancer earlier and monitor the effectiveness of drug interventions quickly and individually. We know that early detection of disease cures cancer by surgery alone for cervical, colon, and esophageal cancer.
Implementing this new approach relies on exploiting recent technology and knowledge in the area of molecuBasic Science Leads the Charge in the War on Cancerlar diagnostics. The completion of the human genome project provides us a guide to all potential protein molecules in our blood. Recent advances in the technology of mass spectrometry allow for an unprecedented analysis of those proteins. Knowing the proteins associated with cancers will allow us to exploit recent advances in molecularly targeted imaging to locate very small tumors and interrogate their molecular features. Drugs attached to agents that seek out the proteins on cancer cells can deliver therapy directly where it is needed. I believe this is what the winning battle with cancer will look like.
Mr. Leaf calls for a coordinated assault on this disease, an approach also championed by Dr. von Eschenbach. Why a coordinated assault? We learned from the human genome project that achieving some goals in biology requires the type of coordination that is common in physics and engineering but rare in biology and medicine. This is one of those goals. Many players in the cancer community are needed to implement a major direction change from a focus on drugs for late-stage disease to one using effective diagnostics at earlier stages for detection and treatment. A paradigm shift cannot be effective if it does not engage the entire community. With NCI leading a coordinated effort involving the research community, the Food and Drug Administration, pharmaceutical and biotechnology industries, and advocacy groups, we can win the war on cancer.
Dr. Leland Hartwell is President & Director of the Fred Hutchinson Cancer Research Center


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HIV-1 Specific Immune Responses in Thai Individuals With HIV Dementia
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
A total of 60 participants will be enrolled. They will be in 3 groups
- ARV-naïve, HIV-positive ≥ 20 year of age with HAD (n=25) who intend to start ARV
- ARV-naïve, HIV-positive ≥ 20 year of age without HAD (n=25), who intend to start ARV
- HIV-negative ≥ 20 year of age (n=10). The protocol team will work with the primary care physician to ensure that the subjects receive standard HIV and ARV care; however, initiation of ARV is not a requirement of the study and ARV will not be provided by the study.
Participant accrual will include 10-15 participants per year. HIV-positive subjects will be tentatively enrolled in HAD vs. non-HAD groups by the enrolling neurologist and subsequently confirmed to that group by a consensus conference held every 6 months by the study neurologists. In cases of disagreement, cases will be re-assigned to the consensus conference determination and recruitment will continue. An external validation consensus conference will be conducted as well every 6-12 months to monitor correct assignment of the level of impairment.
HIV Infections
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
PBMC, Plasma, Urine
|Estimated Enrollment:
|Study Start Date:
|September 2008
|Estimated Study Completion Date:
|September 2012
|Thai HAD individuals (25 cases)
|Thai Non-HAD individuals (25 cases)
|Thai Non-infected individuals (10 cases)
Detailed Description:
This application focuses on the role of cellular immune responses in HIV dementia (HAD) versus non-HAD individuals in a cognitively characterized cohort followed for one year.
Increasing evidence links strong CD4+ T helper function to robust CD8+ CTL responses. HIV-1-infected individuals who are able to maintain strong HIV-1 specific T cell responses have better clinical outcomes and rarely develop neurological signs or symptoms. Monocyte/macrophage (M/M) infiltration into the white matter of the brain is a hallmark of HAD; however, the mechanisms by which M/M are recruited to the brain are not clearly understood. We hypothesize that the loss of specific HIV-1 T cell response results in activation/dysregulation of M/M leading to their accumulation in the brain.
To test this hypothesis will characterize Thai HIV-1-infected individuals as follows: 25 HAD individuals, 25 CD4-, education-, gender-, and age-matched non-HAD individuals and 10 HIV negative controls. We will then: 1) define CD4+ and CD8+ T cell function by evaluating HIV-1 specific responses in HAD vs. non-HAD groups; 2) simultaneously correlate these responses to M/M subpopulation cell number, percentage, and immune function; 3) correlate these responses to HIV-1 proviral load and autologous viral sequences (viral escape sequences and HIV quasispecies); and 4) evaluate the impact of ARV on dementia related to changes in immunological responses. Since little is known of the interaction between CD4+ T helper responses, CTL function, and the level of M/M subpopulation activation in the neuropathogenesis of HAD, this innovative study will elucidate the role of HIV-1 specific immune responses in HAD and provide new insights into HIV-1 neuropathogenesis and its relationship to peripheral immune responses, potentially opening exciting new areas for further investigation.
|Ages Eligible for Study:
|20 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
A total of 60 participants will be enrolled. They will be in 3 groups
- ARV-naïve, HIV-positive ≥ 20 year of age with HAD (n=25) who intend to start ARV
- ARV-naïve, HIV-positive ≥ 20 year of age without HAD (n=25), who intend to start ARV
- HIV-negative ≥ 20 year of age (n=10). The protocol team will work with the primary care physician to ensure that the subjects receive standard HIV and ARV care; however, initiation of ARV is not a requirement of the study and ARV will not be provided by the study.
Inclusion Criteria:
Group Thai HAD individuals
20 years of age
- not currently receiving nor have ever received antiretroviral medications
- not explained by opportunistic infections or causes other than HIV on the basis of clinical assessment and neuropsychological testing and eligible for inclusion.
Group Thai Non-HAD individuals
- will be matched with a seropositive Thai patient with similar age (same decade), education (less than high school degree, high school degree +/- some college, college degree +), gender, and CD4 group
- HIV positive
- not currently receiving nor have ever received antiretroviral medications.
Group Thai Non-HAD individuals will be matched with a Thai seronegative patient by age (same decade), and education (less than high school degree, high school degree +/- some college, college degree+), and gender.
Exclusion Criteria:
- Head injury with loss of consciousness greater than 1 hour
- Current or past illicit drug use (less then 5 years) or positive drug screen for amphetamine, methamphetamines, cocaine, marijuana, or narcotics at either screening or entry.
- Inability to provide informed consent or lack of designated surrogate who can provide consent
- The following laboratory values:
- PT/PTT > the upper limit of normal (ULN) or INR > 1.1
- Hemoglobin < 9.0 mg/dL
- ALT > 5x ULN
- serum creatinine > 2x ULN or creatinine clearance < 30 cc per min by Cockroft-Gault formula
- Acute illness within 30 days prior to entry, persistent and active AIDS- defining opportunistic infection or autoimmune disease. Stable treated opportunistic infections on maintenance therapy, minor infections such as oral thrush and Kaposi's Sarcoma limited to the skin will be allowed.
- Current or recent fevers or meningeal signs suggestive of CNS opportunistic infection.*
- History of pre-existing neurologic disease to include stroke, multiple sclerosis
- History of psychiatric illness including schizophrenia, bipolar disorder, anxiety disorder, panic attacks, or post traumatic stress disorder. Patients with active major depression will be excluded as well - patients with past depression that is controlled and patients with or minor depressive symptoms will be allowed to enroll.
- Known learning disability including dyslexia.
- Positive Hepatitis C serology (Hepatitic C Ab)
- Confusion or other signs and symptoms of metabolic encephalopathy or delirium
- Mass consistent with opportunistic infection or tumor on CT or MRI of the head, or focal neurological deficit on examination consistent with possible brain lesion.*
- Other conditions that could explain neurocognitive decline in the opinion of the investigator such as hypothyroidism, vitamin B12 deficiency or neurosyphilis.
- Pregnancy.
- Not willing to take an MRI.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00777426
|Contact: Jintanat - Ananworanich, MD
|662-254-2566 ext 101
|Contact: Somporn - Tipsuk, RN
|662-254-2566 ext 107
|SEARCH Thailand
|Bangkok, Thailand
|Contact: Somporn Tipsuk, RN 662-254-2566 ext 107 firstname.lastname@example.com
|Principal Investigator:
|Jintanat Ananworanich, MD
|South East Asia Research Collaboration with Hawaii
Additional Information:
No publications provided
|Responsible Party:
|Somporn Tipsuk, SEARCH ,Thailand
|ClinicalTrials.gov Identifier:
|NCT00777426 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 21, 2008
|Last Updated:
|July 21, 2011
|Health Authority:
|Thailand: Ethical Committee
Keywords provided by South East Asia Research Collaboration with Hawaii:
HIV positive with HAD
Additional relevant MeSH terms:
HIV Infections
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Slow Virus Diseases
ClinicalTrials.gov processed this record on September 22, 2014


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Moderators: Jenise, David M. Bueker, Robin Garr
Tom Troiano wrote:'85 Graham's tonight with Colston Bassett Stilton, Reypenaer VSOP, candied apricots, nuts, dates.
Bob Parsons Alberta wrote:Sure to be of interest Tom, look forward to a TN.
Tom NJ wrote:...she wanted to see if they do any better with their dry version.
Jon Peterson wrote:I'll be with James Roscoe on Saturday so who knows what'll happen or what we'll be drinking!
Sam Platt wrote:However, the Primitivo is not horrible and from my very limited experience is the best that Chat Thomas offers. I hope that is what she bought.
Drew Hall wrote:I'm opening a 2007 Chappele-St-Arnoux Vacqueyras. One of a case that I've had squirreld away for a while because it's cold today in Maryland....that's a good reason, right?
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Two teenagers died, two others were seriously hurt in a Nov., 2012 crash in Detroit. Sunday, one of the survivors came home -- with a warning for other teenagers.
Click on the video player to watch Robin Schwartz's report.
"Don't get into stolen cars. Say no," says Enijah Lamb, 15, of Detroit.
The teen suffered a brain injury and other serious injuries when the stolen car he was riding in with four other teenagers slammed into a tree. Two 15 year olds, his cousin and his best friend, died in the crash. One other teenager survived. Police say the car was going about 100 miles an hour on the 5400 block of Holcomb when the driver lost control. The car burst into flames.
"How's it feel to be home?" we asked. "Good," Enijah answered. "What did you miss the most about being away?" "My family," he replied.
Doctors kept Lamb in a medically induced coma for 6 weeks after the crash. He's still unable to walk on his own.
"Only thing they said, they don't know how he's gonna end up. Is he going to wake up? Is his brain going to come back to normal? Is he going to walk?" said Enijah's mother. "I pray to God every day every day that he is gonna come through this."
Enijah's stop home was only a visit. He'll head to a group home for more rehab and to learn how to walk again. Family members say it could be six more months before he's able to return home for good.
WTXF-TV330 Market StreetPhiladelphia, PA 19106-2796Phone: (215) 925-2929Fax: (215) 982-5494


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I have a small floating weed in my pond. I think it is duckweed, how do I know and how do I treat it?
Jason – Raleigh, NC
Duckweed can be a real nuisance if not identified and treated correctly. As it is a prolific grower it can quickly make your pond or lake look more like a golf course in a relatively short period of time. Duckweed is a small floating weed with a single root hair extending from the bottom of each individual leaf. Each green leaflet is about 1/8" of an inch in size and you should be able to fit about 5 to 10 on the tip of your finger. Duckweed can sometimes be confused with watermeal which is also a small green floating weed. Watermeal differs from duckweed in that it is much smaller and has a grainy or almost sandy feel to it if you hold it in your hands.
You can treat duckweed with two different methods. The first method is by spraying contact herbicides like Pond Logic® Pondweed Defense™ or Redwing™ directly onto the floating masses with a pressurized tank sprayer. This method typically yields fast results but tends to be a quick fix that ends up resulting in new growth reforming over just a few weeks. If you need to whip your pond into shape for a planned day or two event, then spraying your pond with a contact herbicide may be an appropriate treatment for you.
For longer lasting control of duckweed you can treat the pond with WhiteCap™ aquatic herbicide. This product works by inhibiting the plants ability to produce carotene and as a result chlorophyll is degraded by the sunlight and the weed dies. There are however a few things you will need to check before adding it to your pond to ensure a successful treatment. Most importantly, WhiteCap™ has a 30 day irrigation restriction meaning that if you water your plants or grass with your pond water you will not be able to do so for at least 30 days. Secondly, Whitecap needs to maintain a high concentration in the pond for up to 90 days. If your pond is prone to overflow or has an inlet/outlet chances are that the WhiteCap™ will rinse out of your pond to quickly making the treatment less effective. A good way to visually check your water loss is to color the water body with pond dye. Dye will typically remain in your pond for 2-4 weeks in normal conditions. If your pond looses color sooner then it is a great indicator that too much water is exiting the pond.
As WhiteCap™ is degraded by sunlight it is important that you dye your pond while you are chemically treating the water body. When applying WhiteCap™ use a pressurized tank sprayer and submerge the spray nozzle to apply the herbicide beneath the surface of the pond where it is safe from evaporation and sun exposure.
The best time to use WhiteCap™ is early in the spring a couple of weeks before you normally see duckweed forming in your pond. This will give the herbicide a chance to establish itself in the pond and discourage plant growth before it gets out of control.
Pond Talk: Have you experienced Duckweed in your pond?
Filed under: Cattails, Chara (Algae), Duckweed, Emergent Weeds, Phragmites, Pond & Lake, Pondweeds, Uncategorized | Tagged: cap, pressure, tank sprayer, Watermeal, weed control, white | 4 Comments »


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Borderlands 2 trailer visits the mighty jungle
It's not hard to get excited about Borderlands 2, but the new trailer Gearbox has released showing off a new jungle environment and beasties will have you singing its praises even more, with emphasis on singing.
The choice of The Lion Sleeps Tonight for this action-packed video works much better than the last trailer's dubstep, but now I can't get the stupid song (or the wacky images) out of my head. It looks like the trailer accomplished it purpose.
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Charlotte Jane
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(CLOSED)1500 Points Raffle(CLOSED) 1500 Points raffle :iconsealglompplz:How to join just fave this journal The raffle will end in 3 daysgoodluck :iconkissingplz:
[CLOSED+WINNER] Adopt Raffle 09 - MemoriesHi \;///v///;/ Thanks again for the support T////T I receive so many comments ;__; all so kind T////Tnnngh you have so wonderful idea for them ;__;Forgive again for the late Now I have the winner of the raffle \;//v//;/ <3 <3 <3This is :iconAzaikar: waaaah I'm so happy for you T////v////T <3 <3 <3 \;//v//;/Now Azaikar can choose her favorite in the batch and the others will be put on sale \;//v//;/ ( I'll make a poll before sell them ;u; <3 <3 )THANKS A LOT AGAIN TO EVERYONE *cries* ç__ç I feel very happy T////T <3 <3 <3HAVE A WONDERFUL DAY SEE YOU SOON IN THE NEXT RAFFLE Feel free to remove the journal from fav if you wish Waaah such a long time we didn't make a raffle >///v///< We really love doing that so this time we try with our new project "Memories" , Little Owl/penguin ( x°D )We hope you like them \;///v///;/
How to Spot a Fake ApologyDid you know that I know how to spot a fake apology? It's actually kind of like a super power of mine. But more to the point, a lot of people who get blocked on any of my various social media sites want to get around their blocking just to do whatever the hell they did to get them blocked, but some of them are genuinely repentant. How do you spot the difference, because to tell you the truth, it's not always easy. I'm going to go more into detail about this in Brian's a Bad Father because it has some of the worst, most half-assed non apologies that I've ever seen. Well mostly. Reality is stranger than fiction. But I'm going to use that episode as some of these examples, along with things that people have actually tried to say to me to pretty much do the same shit again.How many first person pronouns do they use?This is the rule of thumb. If there's a first person pronoun that doesn't involve "I'm sorry" or "I messed up pretty bad" or something along those lines, it
1000 Points Giveaway! 1000 Raffle How to enter? All you have to do is this journal. Winners? 1st random - 5002nd random - 2503rd random - 250 The random winners will be picked using the random.org sites "True Random Number Generator" to pick the lucky winners from the favourited list.Closes on 21st of September.Good luck to you all!
2500 Point Giveaway [OPEN] #5Hi guys! Just for anyone interested and/or that is really needed points, simply follow info.*and if you want help, please contribute a small or big donation, would be a great value! ♥ Enter in my profile page: ~~Help-donate-points~~ ---------- ----------I would like to thank the support of&
Regarding Recent EventsHey everyone.Unfortunately, today's journal isn't a cheery one. For those of you who are active on tumblr, I'm sure you're already aware. But I'm also sure that there are still some of you who have not yet been informed. Comickit, whom I'm sure you know as the artist of "Pasta Monsters", recently released her statement on the abuse she suffered at the hands of Snuffbomb during their time dating one another.http://comickit.tumblr.com/post/97829561023/why-your-date-with-snuffbomb-was-badThis act of bravery sparked countless others to step forward with accounts of unspeakable abuse ranging from emotional to physical and straight up sexual assault. Due to the overwhelming number of people that have stepped forward, an entire page has been made to document them all.http://snuffbomb-victim-awareness.tumblr.com/Now, as I'm sure you all clearly remember, I personally went through a rough patch with Snuffbomb myself not too long ago. The result was my removing him from the cast of "T
Your character in Missing Halloween! (RESULTS)MISSING HALLOWEENINTRODUCTIONIn August 21, "Your character in Missing Halloween!" mini-contest was announce.In September 1, a total of 313 character designs were submitted. Judging has begun.As the judge, there were 313 submissions, and only 32 to choose from. Trust me, it was haaaarrd! It still pains me that so many great designs didn't get in. (It's just that many) But I still did my best to judge them carefully.So here goes, the results!!!THE TOP 5 CANDY GIVERSAs mentioned, there will be 5 characters who will be featured as candy givers! (And their owners to be in the credits as "Additional Character Design")And here they are!!!:iconAndrea4You: Andrea4You's character: Akai:iconSkunkyfly: Skunkyfly's character: Amber:iconShiroXIX: ShiroXIX's character: Pydur:iconinkstainkat15: :d
[Giveaway] 400 WATCHERS / 14 500 PAGEVIEWSGuys, you're the best.I can't believe this; 400 watchers? AND 14 500 PAGEVIEWS? ...That's a lot of attention for a simple 14-years-old school girl like me. So I decided to make my first Giveaway! GIVEAWAY This is the 400th watcher milestone. The 1st place will win 700 The 2nd place will win 300 The 3nd place will win 150 The winners will be chosen via random. The deadline is the 28th of September 2014, Midnight GMT.
200 Point Giveaway~:iconpumkinplz::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconpumkinplz:There will be Three Winners.First place will get 100 Second will get 50 Third will get 50 You must Favorite this Journal and Watch me to enter.The Date the winners are announced is October 1st:iconpumkinplz::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconstardividerplzL::iconstardividerplzM::iconstardividerplzR::iconpumkinplz:I will be using Random.orgHow does this work? See the thing on the Side that shows a list of who Favorited the Journal? Next to the names there are Numbers.Random.org randomly picks Numbers, So the Person with tha
A Guide to a Man's Erogenous ZonesThe main difference from the Western from of massage and also the Tantric one is how the whole body may just be touched, which, in accordance with the followers of it ancient art, is sizzling for the sexual energy to remain channeled and presented.Can everyone be able to perform Tantric massage? Even though the true Tantric techniques and also elements take years for those followers to excel at, you can easily understand how to perform this kind of massage on your honey, especially if you might be guided by the therapist. In the majority of instances, the sessions as well as short breathing workout routines, gazing, or creation, which prepares the receiver and also the giver and syncs their energies. Therefore, the session is and then what is just a full figure sensual or lusty massage, which incorporates typically the touching of the male or female sexual organs. The male sexual organ is referred to as Lingam (although the expression has deeper meaning) as well as t
ReflectionsVal's pursuit led him to the foul beast's domain. The hollowed-out cavern reeked of blood and rancid meat. The dim light he had seen as he charged through the tunnel after the monster could now be identified: torches. Rows of mysteriously lit torches lined the walls of the huge cave. At its center was a substantially large labyrinth of mirrors.He spotted the beast entering.He spun his silver broadsword in his hand and hurried in behind it.His garb was a simple blue and white crusader's leather with thick armored pads and reinforcing steel studs. Lightweight and flexible, but quite effective defense against blunt blows and – in a pinch – the slashing claws of the unholy spawn of the earth. All monster-hunters wore a similar variety in Val's experience. It would serve him well in these close quarters of the mirrored maze.Right, left, forward, left, right he turned, always catching a glimpse of the beast's tail as he wove his way through the corridors. Every so often he sp
lovelies,Please read
the journal
carefully.This is my
second watchers
raffle. First one's
winner was
@OhSquishy and
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This time, the
winner will get a
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these: Rules: You
have to be a watcher
of mine before this
journal was posted.
If you want to
Read More
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When you're at the grocery store, do certain words draw you to specific products? The buzzwords that made you buy used to be "low fat" or "fat free." But now a new word sucks buyers in: "protein."
Protein is advertised on boxes of cereal, yogurt, granola bars, and even chocolate milk. More and more food companies are boasting about the protein in their products, and that's no coincidence.
"Protein is word of moment," said Adam Hanft, a brand strategist. "We all want it so if you can position your brand to have protein it's a win."
Hanft said that protein has become the latest nutritional buzz word and that consumers are biting in to the promises of more energy and feeling fuller longer.
"We're not getting any more sleep, we all want to lose weight and avoid sugar and carbs, protein is the magic bullet in that environment," Hanft said.
But food packaging is all about selling. Just because a product says it has protein, doesn't mean it is healthy for you.
"Protein is not bad for you, but a product is not made of just one ingredient, like this bar, there's sugar and other stuff," said Rachel Berman, a registered dietician with CalorieCount.com.
Many marketers may try to mask sugar and calorie count with promises of protein, such as this fat-free Nesquik chocolate milk, which is loaded with sugar.
Protein is essential to any diet. Most of us are already getting plenty, Berman said.
"As Americans were getting enough protein but the truth is that it's the only macronutrient that hasn't been demonized, no carbs, no fat, but protein is OK according to Americans," Berman said.
That is why experts say the protein trend is gaining strength and will probably be sticking around.


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Avent Manual Breast Pump
- In Stock
3 reviews
- Delivery
- Next day delivery available
Being stressed or in a hurry can make it more difficult to release your milk and can also affect your milk supply, so feeling comfortable and relaxed is key.
The gentle draw vacuum that mimics a baby's natural suckling action gets more milk than a hospital grade double electric pump and the unique massage cushion is intended to help stimulate natural let down. Make your life easier by expressing directly into any of AVENT's wide range of bottles and storage containers.
- Gentle with clinically proven results
- Unique soft massage cushion for optimum comfort
- Includes 125ml durable bottle, travel teat (plastic casing to store teat safely for travel), bottle stand, breast pump cover and sealing disc
Avent Baby Bottle Feeding Essentials Set
- In Stock
4 reviews
- Delivery
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The Avent Baby Bottle feeding essentials set is a great value pack containing all your feeding essentials! The set includes a microwave steriliser with 4 bottles, milk dispenser, therma bag, brush and teats.
Fits most microwaves - convenient for travel. Holds 6 Avent bottles. Just add water, load and place in the microwave. Contents remain sterile for up to 24 hours if unopened. Two piece anti colic system - allows air into the bottle rather than your baby's tummy. BPA Free. Clinically proven to significantly reduce fussing.
- For sterilising and cleaning: 1 x microwave steriliser, 1 x bottle and teat brush, 1 x measuring jug and 1 x tongs
- For feeding: 2 x 125ml durable bottles with newborn teats, 4 x 260ml durable bottles with slow flow teats, 2 x medium flow teats
- For travel: 1 x therma bag and 1 x milk powder dispenser
Avent Microwave Steam Sterilizer
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3 reviews
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The Philips AVENT Microwave Steam Steriliser SCF281/02 has a lightweight and compact design, which makes it ideal for use in and out of the home. Contents remain sterile for up to 24 hours if the lid is unopened.
Ultra fast and easy to use!
- Sterilises your bottles in as little as 2 minutes.
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Included in pack:
- 1 x Microwave Steam Steriliser
- 1 x Tongs
Avent Classic Feeding Baby Bottle 260ml/9oz Twin
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2 reviews
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Good feeding, good sleeping. Helps settle your baby, especially at night. Fussing is by far the most commonly known crying behaviour in babies. The Philips AVENT Advanced Classic feeding baby bottle significantly reduces colic and fussing. Fussing is reduced especially at night. Age from birth.Colours: Blue or Pink.
Avent Newborn Starter Baby Bottle Set
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The Avent Newborn Baby Bottle Starter set is a fantastic set for new mum's and also Grand parents who need essentials when baby comes to stay!
- Clinical studies show that the AVENT bottle significantly reduces colic and fussing.
- This bottle is made from PP - a BPA free material
- Allows air into the bottle instead of your baby's tummy
- Suitable from birth
Set includes: 2 x 125ml extra durable bottles with one extra soft new born teat, 2x 260ml bottles with one extra soft slow flow teats, one bottle and teat brush and one Philips AVENT Soother.


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Duration: 15 minutes
The latest business news from around the world, with live reports from Singapore, Frankfurt and London, and news of what happened overnight in New York.
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Hi Everyone,
Join me on Wednesday, December 10th at 8 pm EST for a Christmas crop. This is NOT a speed scrap. You'll have up to 24 hours to complete your lo and this one has a special twist to it. The twist is a surprize. Just meet us here with one or two Christmas or snow photos at the above time.
Please be prepared to do a Christmas, winter themed AND snow lo, preferrably with at least one GDS product!! And be prepared to have FUN!!!
(Even if you can't be here at the above time you may still be able to participate. pm me for details BEFORE the crop starts.....)
Anyone completing a lo and posting it in our gallery within 24 hrs. will get a small reward from me. It's the qp below:
Hope to see you then......
(Add a reminder for this event by going here: http://www.godigitalscrapbooking.com...reminder&e=508 )


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News about Sushi, including commentary and archival articles published in The New York Times.
Chronology of Coverage
Mar. 16, 2014
Several culinary schools in New Jersey offer sushi-making classes for beginners that teach rice preparation techniques and knife skills; socializing with others is part of the appeal (Metropolitan/New Jersey). MORE
Oct. 30, 2013
Young sushi chefs around New York City are toning down the rigid style often found at high-end sushi bars and are taking a more adventurous attitude towards preparing the fish-and-rice specialty. MORE
Jul. 21, 2013
Ken Belson travel article on trip to Hokkaido, Japan, in search of most delicious uni, or sea urchin, island has to offer. MORE
There are no additional abstracts to display.
Obama's First Order of Business in Tokyo: Sushi From the Master
President Obama and Prime Minister Shinzo Abe had dinner at Sukiyabashi Jiro, whose chef was featured in the documentary "Jiro Dreams of Sushi."
April 24, 2014, Thursday
MORE ON SUSHI AND: Japan , Restaurants , Kennedy, Caroline , United States International Relations , Abe, Shinzo , Sushi , Rice, Susan E , Jiro Dreams of Sushi (Movie) , Tokyo (Japan) , Obama, Barack , Ono, Jiro
A Sushi Guide, Designer Tableware and More
Recommendations for the week of April 15.
April 16, 2014, Wednesday
MORE ON SUSHI AND: Chocolate , Weiss, Alexander , Sushi , Herbs , Tableware , Cooking and Cookbooks , de la Renta, Oscar
Making Sushi and Friends
Several culinary schools in New Jersey offer sushi-making classes for beginners that teach rice preparation techniques and knife skills. Socializing with others is part of the appeal.
March 16, 2014, Sunday
MORE ON SUSHI AND: Viking Cooking School , Cooking and Cookbooks , Sushi , Sur La Table , New Jersey , Classic Thyme Cooking School , Chef Central , Kitchen Kapers
Balancing Private and Public Needs
In some developing countries, there is more confidence in the raw fish than the tap water.
January 21, 2014, Tuesday
MORE ON SUSHI AND: United Arab Emirates , Third World and Developing Countries , Water , India , Sushi , Argentina
Sushi's New Vanguard
All over New York, a more adventurous attitude awaits.
October 30, 2013, Wednesday
MORE ON SUSHI AND: New York City , Sushi , Restaurants , Manhattan (NYC) , Chefs
Restaurant Report: The Blackanese Sushi & Wine Bar in Johannesburg
At this spot, opened in one of the city's creative havens, sashimi and sushi mingle with a few surprises thrown in for homegrown palates.
October 13, 2013, Sunday
MORE ON SUSHI AND: Travel and Vacations , Sushi , Restaurants , Johannesburg (South Africa)
A Way of Life Moves With a Market
Tokyo is spending $4.5 billion to relocate a 78-year-old fish market to accommodate modern truck traffic — a move critics call another blow to a vanishing way of life.
September 17, 2013, Tuesday
MORE ON SUSHI AND: Ishihara, Shintaro , Fish and Other Marine Life , Seafood , Japan , Olympic Games (2020) , Sushi , Tokyo (Japan)
In Japan, Searching for Prized Sea Urchins
A quest for the freshest uni takes the author to Hokkaido, a seafood lovers' paradise north of Tokyo.
July 21, 2013, Sunday
MORE ON SUSHI AND: Sushi , Restaurants , Fishing, Commercial , Hokkaido (Japan) , Travel and Vacations , Food
Mergers: Equity Firm In Europe Acquires Stake In a Sushi Chain
The European private equity firm Permira has struck a deal to acquire a Japanese sushi restaurant chain, with plans to help it expand overseas. The agreement values Akindo Sushiro, an Osaka-based operator of sushi bars in Japan, at roughly $1...
August 25, 2012, Saturday
One Item on the World Menu Has Its Critics
A documentary examines the popularity of sushi and questions its sustainability.
August 3, 2012, Friday
MORE ON SUSHI AND: Sushi: The Global Catch (Movie) , Movies , Sushi , Hall, Mark
Rss Feeds On Sushi
Subscribe to an RSS feed on this topic. What is RSS?
Get Alerts On Sushi
Receive My Alerts e-mails on topics covered on this page.More Alerts >>


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|Product Catalog > Retail Catalog > Kick > Oregon "Juice Facile" Footbag
Customer Reviews:
good bag. I told them about a defective one that i got and they replaced it. Just noticed that the one I got was a Juice facile bag not an OREGON juice facile. 8 stitches on each side of defective OREGON one. 4 on the replacement that is actually just facile. plus the design is only shown on the regular one, NOT on the OREGON one. -- Stephen