text: Take a look at the latest men's arrivals to the River Island online store! We update our site with new products every day so that you can get your hands on the latest fashions before anyone else. Simply head to our Just Arrived section and have your clothes delivered direct to your door at the click of a button!


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I have no internet and I am so angry at my ISP, with whom I've spent 7 hours and counting so far, both on phone and in trips to the local office to replace the modem. They deny there is an outage. The store was out of modems because 100s of other people had been sent there to replace their suddenly and inexplicably defective modems. The new modem failed to solve the problem also. Another mom at the school said that she'd been without internet for two days because they're doing an upgrade and they need to come out and change a setting on the pole outside the house. Nobody at the company will acknowledge anything like this is going on but do say there is an upgrade.
I'm still on hold. I'm so frustrated. Soonest appointment is Sunday. I miss you. Plus I have things I need to do.
L, wow. That's a long time to be out of service! You'd think - especially in a metropolis - there'd be no excuse for such an extended downtime. Internet's totally a utility nowadays. Imagine if your water were out until Sunday. I'd almost sooner go without brushing my teeth!
I'm on B duty tonight so DH can get some sleep. Hoo, but I'm tired! DH is in there mumbling in his sleep about his new truck, which was kind of a surprise buy. I mean, I supported it, but I'm really the one with the 303,000 odometer on her car who's in the car market. DH just needed more room for Bodhi, so he went from an extended cab pickup to a 4-door. It's just as well, I'm too indecisive for myself, and my vehicle's still going strong.
Bodhi just laughed in his sleep.
Erin, I know you don't visit as often, but I hope you're all well.
Edited out: <<TMI>>>
Good grief, I need to sleep! Between the moral marital dilemmas, late offshore calls for work, my gramma worries, and Bodhi's night wakings, my head is too full to go into REM.
Last edited by demigraf; 06-03-2013 at 12:24 PM. Reason: Typos! Typos! Typos!
Bridget, since you're a busy mama and might not get back to FB to see my reply to your story about the crockpot, I'll paste it in here:
"Mmmmmmm... it's a soup. It's an enema. It's both!"
See? Instead of vaguebooking, we now have Vague-PA-ing. Hee!
Myles, you're simply a good person who assumes everyone else is as good as you. There's nothing wrong with that. His fishing is a reflection of him, not you. The worst thing that would have happened if you continued your innocent friendship is he would have shocked you with an outright come-on, and I have no doubt you'd have quickly and unequivocally put him in his place. Now, you're getting to avoid all that. I think it's great that you shared that with us and were receptive to our point of view. Again, it reflects very well on you.
Ha, Myles! If only the soup had been edible- much less, smellable.
That text made me laugh too. Although, the cynical part of me thinks he is less diffusing tension and more flirting. Don't beat yourself up, however. I, for one, might hesitate to walk away from all of that flattery myself. You are pretty fabulous and it must feel wonderful to hear it. I'd eat that right up.
Conner had a game last night and he got to be catcher, but he didn't like it at all. I don't think anyone really explained clearly to him how to squat and no one was paying attention (hello coach dad!) so he was on his knees leaving his kneecaps completely exposed, so you know what happened? Yeah, a ball cracked him right in the knee cap. The poor little guy. I could tell he was hurt and his father was yelling from 3rd base area to 'get up' and hold his glove up. He finally got someone to help him get in the right position, but after that he was so terrified of the ball he wouldn't move a hair to try to catch it. It broke my heart to pieces.
Other than that, though, baseball is going great for him. He loves it and he's one of the 'big hitters' on the team. I was sitting on the opposing team's benches (chatting with a friend I hadn't seen in a while) and I heard one of the older gentlemen remark, "That kid has a great swing!" when Conner was up to bat. He usually hits the first pitch too, but that time he got the 2nd one.
I'm so stinking proud of him!! Last night as I was tucking him in to bed he asked if he had a game today. I had to tell him no, but he does have one Saturday (two sleeps). He's going to be so sad because next week he doesn't have 1 game at all. I think we're both going to cry when this season is over.
Poor Conner
Ugh. I was a softball catcher. It's not just the squatting/kneeling. It's the weight of the gear and face mask, especially on a hot summer's day, and also throwing to second base. Is he going to keep that position? Hope he doesn't have to.
But way to go to your slugger!
Nolan's new response anytime we mention the baby or him being a big brother/getting a little brother or sister is "Ewwww baby" Sigh. I really don't think he is going to take a new addition very well
He's also been mad clingy to me. Prefers me to do everything. He'll yell at me across the house, when DH is in the same room with him, if he needs a drink, butt change, etc. and than tell DH "No mommy do it'" if he tries to intervene. It's really got hubs feelings hurt, though he understands its natural, he just misses Nolan wanting him, and I am tired of being so wanted
It's entirely possible he'll completely change once the baby is here. Trust me. I've been through this myself. I don't remember any of the older siblings being 'too much' once the new baby finally arrived. I think the anxiety of the unknown triggers a little neediness prior to the birth of a baby, but it vanishes.
ETA: and holy crap Jesi is in her second trimester gramama!!
Kind of reminds me of the convo I had with B last night:
B: Mommy, I'm in love with you.
Me: Well, your daddy & I are in love with each other. When you grow older you'll be in love with someone else. You love me, but you're not in love with me.
B: No, I'm in love with you.
Me: No, sweetie. You love me. Your daddy is in love with me.
B: No, I'm in love with you. And I want to be with you forever. And I never want you to ever love another boy.
Now I'm a little scared of the conversation if we ever welcomed another baby into our home.
Side Note - M, not that you asked, but I totally vote you make more babies.
I guess you'll just have to have a girl then, Myles!
Christina, in most cases, the kids adjust just fine once the LO is here. What my mom did with us when my brother was born, was to give me some level of authority over him. She told me that he is a baby and he doesn't know anything, and as a big girl, it was my job to teach him stuff, how to sit and walk and run and jump and eat and... and basically, that I was the boss of him to some extent. Obviously, I wasn't actually the boss of him, but it didn't hurt to be put in charge.
Oh, cute story aside. My brother was the only boy, to three girls (on my mom's side; I have two older girl cousins), and he was so excited to find out that my aunt had had a son. He was full of plans for what he'd do with him, and went to the hospital, all excited about how they were going to play together. He took one look at the newborn, and ran out of the room, crying. When asked why, he said that this baby only had a head (the rest of him was in the swaddle), and how is he going to play with something that only had a head
Last edited by Suja; 05-17-2013 at 11:09 AM.
Savana was so not cool with having a baby brother. BUT, I was alone with the 2 of them and going through a very difficult time in my relationship with dbf (he was still in Hawaii, me in WI trying to start my new daycare business with 2 young children) so I sure the general vibe of the house was not conducive to her feeling totally secure. I was kind of a mess. The first 2 years of Kai's life are such a blur to me. BUT now they are best friends. Practically inseparable. My enter key does not work in this thread. Only this one though! Strange.
S, I like that! Nolan is very, very independent and he would probably like being 'in charge' like that. I'll have to brain storm and see how we can incorporate that. We did talk about getting him a 'gift' from the baby, but I wasn't sure if that was silly or not
The story about your brother, seriously, almost made me pee my pants Priceless!
Oh my goodness, I'd have died if I'd been there, Suja.
Bridget, you did it mama! You'll always have that, and your lucky kids'll always have you. How cool is that?
Aw, that's sweet about Josh being excited. Travis has told me he wants a sister, so I've told him that he can consider his cousin M his sister since we see her and her 2 brothers nearly every day any way. LOL. It might have been nice to have a girl, but we definitely are happy with 2 boys and like that our life is progressing along nicely.

subset: commoncrawl


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Former Detroit Mayor Kwame Kilpatrick and his longtime friend Bobby Ferguson are headed behind bars to await their sentences.
Federal Judge Nancy Edmunds says it's a "close call" but the scale under law is tipped more toward prosecutors. She made her decision Monday, four hours after a jury convicted Kilpatrick on 24 charges, including racketeering conspiracy, bribery and tax crimes.
Prosecutors argued that Kilpatrick lied to prosecutors in the past and that Ferguson was a violent flight risk. Defense attorneys argued that Kilpatrick is broke and couldn't afford to flee.
Click here to read a live blog recap from the hearing.Jurors convicted Kilpatrick of a raft of crimes, including a racketeering conspiracy charge that carries a maximum punishment of 20 years behind bars. He was portrayed during a five-month trial as an unscrupulous politician who took bribes, rigged contracts and lived far beyond his means while in office until fall 2008.Kilpatrick wore a surprised, puzzled look at times as U.S. District Judge Nancy Edmunds read the jury's verdict: guilty of 24 charges, not guilty on three and no consensus on three more.
Attorneys can appeal the judge's decision to remand both Ferguson and Kilpatrick into federal custody, but experts say don't expect them to do that.
25 FOX DriveDedham, MA 02026
Phone (781) 467-2525


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Use the Tropicana Field Interactive Map to plan your arrival method, find where to park and how to access Tropicana Field
Tropicana Field is located directly east of I-275 in St. Petersburg. The dome is visible from the highway.
Complete information for lot location, carpool, disabled parking and drop-off locations and more.
Escot Bus Lines can provide charter bus services for groups or parties to and from Rays games during the 2014 season.
For select games, this FREE Baseball Shuttle picks up passengers and drops them off at Gate 4.


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A strong young worker at a construction site was bragging that he could outdo anyone in a feat of strength. He made a special case of making fun of one of the older workmen.
After several minutes, the older worker had had enough. "Why don't you put your money where your mouth is," he said. "I will bet a week's wages that I can haul something in a wheelbarrow over to that outbuilding that you won't be able to wheel back."
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The old man reached out and grabbed the wheelbarrow by the handles. Then, nodding to the young man, he said, "All right. Get in."
For more laughs click Smokin' Joe's Cafe
Photo: By English: Master Sgt. Michael Q. Retana [Public domain], via Wikimedia Commons


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KANSAS CITY, Mo. -- Yu Darvish flirted with a perfect game, and Geovany Soto hit the first of five Rangers home runs as they toppled the Royals 8-4 at Kauffman Stadium.
Darvish retired the first 17 Kansas City hitters before Johnny Giavotella took a 3-2 curveball for a ball even though TV replays showed the pitch hitting the outside corner.Subscribe to Read!


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How to Apply:
-Directly apply to skin
Musk Essence Oil
Our Original Musk Oil is believed to have been created in the 1920's at the "Kiehl Apothecary." Discovered there in a vat labeled "Love Oil" in the late 50's, Kiehl's signature scent was reintroduced to our patrons in 1963.
"A light, clean fragrance that is long lasting!"
Farhanna, Kiehl's Insider
Rollover to enlarge
How to Apply:
Smells different on each and every person who wears it making it one of the most
Unique fragrances out there and no matter where I go I get stopped by young and old men and women alike asking what I have on.
My husband is getting to the point where he says can't you wear some other perfume tonight. But I LOVE MY MUSK OIL BY KIEHLS ONLY. May 23, 2014
asks me what I'm wearing May 10, 2014
saw this product advertised and wanted to try! Dec 18, 2013
She said it used to be a bigger bottle and a stronger scent. May 20, 2013
Began using due allergic to strong or flowery perfumes. Tried the roll-on a few years ago & it wasn't the same, so back to the "original" altho not certain it isn't slightly
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Still my fav smell goods. Mar 21, 2013
Try it, I think you will get positive feedback, especially for the great "clean" smell. Aug 20, 2013
The answer to whether men can use original
musk oil, the answer is yes. The 3 men in my life
use it and no one would ever acuse them of smelling "girly". They alao use the speay. Aug 20, 2013
I do love the bottle better than the roller. I also bought the body wash and the lotion and I get so many compliments about the way I smell when I wear it all together. I am very happy with Kiehl's musk products! Jan 19, 2013
Must be all in the name of making more money. Apr 4, 2013
My signature fragrence. Loved it in the 60's and love iit just as much today Apr 4, 2013
My signature fragrence. Loved it in the 70'and live it just as much today Apr 4, 2013
The ingredients are listed on the box that the bottle comes in.
I have used and enjoyed this product for 50 years.
This is like no other musk product that I am aware of. Sep 5, 2014


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Available at retail stores only.
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The perfect glove for JV, Middle School & Youth players looking for increased flexibility and protection.
- 4 bar backhand design flexes perfectly during the cradling motion for better ball control
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Provides a comfort fit and feel while constructed to hold up to the toughest conditions .


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Customer Testimonial
Gifts For Her department
Choose personalized romantic gifts for your wife, girlfriend or fiancée!
Personalized Romantic Gifts for HerThe special woman in your life deserves an extra special gift to show you care. Get her something that is truly personal and unique, something that was made just for her. At PersonalizationMall.com, you can choose from a great selection of sweet, romantic, and fun gifts for her. After you find the perfect item, add a loving message or personalize it with her name for free. Perfect for Valentine's Day, Sweetest Day, Anniversaries & more!


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Reserve your winter and summer Lake Tahoe lodging package with Northstar California. Choose from condo rentals, mountain homes and hotel rooms with complimentary amenities such as free skate rentals, overnight ski and snowboard storage, on-site shuttle transportation, high-speed Internet access and free unlimited local calls. Plus, guests receive access ($2 per person) to outdoor spas, swimming pools and fitness center.
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Clovis, NM - A man is behind bars after a four-and-a-half hour standoff in Clovis.
The Clovis News Journal says the standoff ended at a home in the 300 block of North Lea Street Tuesday afternoon.
Police arrested Cesar Rodriguez and booked him into the Curry County Detention Center.
It all started when police received a call about a couple from Portales who had spotted their stolen vehicle in Clovis.
Officers attempted to stop the vehicle but the driver sped to a nearby Allsup's.
Then two women and a man jumped out and fled on foot.
The man, identified as Rodriguez, kept officers busy in front of a home until finally giving himself up.
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Directed by: Ridley Scott
Cast: Brad Pitt, Susan Sarandon, Michael Madsen, Harvey Keitel, Geena Davis, Jason Beghe, Christopher McDonald, Lucinda Jenney, Marco St. John, Stephen Tobolowsky


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It is to provide light to the sewing bed. Bulbs come in lots of different shapes and sizes with various bases.
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You could call Tom Duhanaj a friend of the politicians. Records show he's donated to the campaigns of Gary Peters and Carl Levin. He's also posed with other political big wigs like Sander Levin and former President Bill Clinton.The same man is now under arrest, charged with lying to federal investigators and accused of running a loan shark operation for fellow Albanians, including a candidate for the 13th Congressional District, John Goci of Westland."I'm kind of shocked about [the] charges," said Goci. "Not the guy I know. I've seen him around town. He's been really good. He helped me out in my time of need. I'm a small business owner, and sometimes you have ideas and it takes money to make things happen."Goci, who has been questioned by federal investigators, says he received a $30,000 loan and has a picture of the check to prove it, but he claims the money came from Oakland County businessman Randy Dzierzawski. Duhanaj acted as the middle man.How did Goci know to go to him as a middle man?"I heard that in the community, that he knew a guy that was loaning out money, that had access to money, so that's what I did."Sources say Duhanaj charged high interest on his loans up to 45 percent and threatened violence if he didn't get paid.Goci said he was only charged 15 percent and never felt he was in danger when he accepted a loan to help his Wayne restaurant that was going through tough financial times."15 percent. It was a little higher than the bank, but you know what, it's a little simpler to get."On Thursday, federal agents raided Duhanaj's restaurants, Bray's Hamburgers in Westland and Capital Coney Island in Ferndale and his home in Troy, sources say in search of financial records.According to federal court documents, 42-year-old Duhanaj entered this country illegally in 2002 to escape the violence in the former Yugoslavia. He was arrested a short time later and fought for political asylum, but lost. He's been under investigation for months and because of his alleged crimes, he will be deported.Goci claims he never knew of Duhanaj's past and hopes it won't impact his political future."I hope not. I hope people will see through this. I've done nothing wrong. I'm just a small businessman trying to keep my door open."It turns out Duhanaj even donated to Goci's campaign, but he told us he plans to return the $1,000.Although he isn't considered a frontrunner, Goci said he has run a strong campaign and if elected plans to get people back to work and create equality in education.We were unable to reach Dzierzawski for comment Monday evening.
WTXF-TV330 Market StreetPhiladelphia, PA 19106-2796Phone: (215) 925-2929Fax: (215) 982-5494


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Have you got a specific question you'd like to ask us? Advice about a product? Just click in the box below and one of our friendly team will be happy to help you.
We are normally here Mon-Fri 8.30-17.00
Welcome to MapStop Global Mapping's easy to Use Online Map Shop – Top maps at a reasonable price, we select all our products carefully to make sure you will have the best possible choice and be assured all products are covered by our guarantee. If you need any help or advice you can chat with us in real time in the chat box to the left or you're more than welcome to call us on 01280 840770 and one of our friendly staff will answer-we don't have impersonal automated call systems, just humans!
Enter the city, region, country or type of map (i.e.Postcode Map) you are interested in. You can also search by Publisher (i.e. Global Mapping)...
You can make your own maps on demand now, centre it on your location and decide how far you want to cover, show every street if needed, choose how detailed the Postcode Boundaries should be, select from Postcode Areas (NN) Postcode Districts (NN13) or Postcode Sectors (NN13 5) or none at all! You also have the option to create maps of anywhere in the World. It's easy to use so to start creating your own map click here.
The British Cartographic Society presented Global Mapping with its highest award for their Antique Style World Map, the BCS Cup goes to best overall map where the winners from all categories are judged. The map won the Stanford's Award for Best Printed Map 2013.
The aged look of the colour scheme is down to Mary's design skills, the shading in the sea looks like you would feel it if you ran your fingers over it and the Europe inset means you can actually identify the individual Countries! However, what really makes the map are the added extra bits of information explaining the reasons for the Tropics, why the Polar Circles are where they are and most intriguingly explaining what an Analemma is and what it depicts! The scale is 1:30M and measures 1333mm x 766mm and is priced at just £11.99 There is also smaller size at 1:40M which measures 1000mm x 575mm and costs £9.99 Click here for more information
Stargazing has become one of the most popular pastimes thanks in part to the excellent BBC 2 programme 'Stargazing Live'. Professor Brian Cox has made the stars popular, so much so that Global Mapping's Planisphere sold out within months. We've now brought out a new version with a unique double sided disc which allows the novice stargazer to start navigating the sky at night.
Accompanying the Planisphere is the Chart of the Heavens, a beginners guide to stargazing, complete with clear charts and all the background information you need to start stargazing and identifying planets.
Check out the amazing Constellation Mova Globe spinning silently without any visible power source that has to be seen to be believed.
There are plenty of other Stargazing products to view, just go to the Astronomy Section.
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Globes are one of the most fascinating products devised as they provide a true life representation of the world we live in. As an educational product, a globe can bring to life the true concept of living on a sphere, Children in particular are fascinated by the concept of the globe and it is for this reason we stock educational globes as well as those aimed at the adult market.
You will find here a fantastic and wide selection of Globes, from Inflatable Globes and 'Huggables', suitable for small children through to our collection of junior and family globes. MapStop also stocks a wide selection suitable for many other uses whatever your requirement.
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Object Name: lounge suit
Artist/Maker: Stanley Adams
Role in production: Manufacture
Place of Creation: Europe, United Kingdom, England, London
Date: 1971-1972
Accession Number: 1980.370
Image Copyright: © Manchester City Galleries
Credit: Manchester City Galleries
Blue brushed denim cotton suit.
Jacket; single breasted, fastening with one small blue plastic button; made with six body panels, underarm seams projecting towards centre front; two long vertical darts at front; wide rounded lapels made without button holes; breast pocket headed by 1 inch band of self fabric, lined black cotton, deep rectangular patch pockets with flaps at hips lined black cotton; pockets and collar topstitched; back has 14 inch slits at sides, now ripped at the top; sleeves made in two pieces; two small mottled blue plastic buttons sewn at each cuff; coat lined throughout in nay acetate; lining ripped in places; extensively padded with foam plastic at shoulder and chest; navy ribbon hanger, inside pocket at right breast; black artificial silk label sewn beneath with the following woven in white "Stanley Adams, London".
Trousers; flared style; 2 inch waistband, with 3 inch extension at centre front, fastening with flat chromium plated hook and loop; interior fastening mottled blue plastic button at top of zip fastening fly (zip corroded). Two horizontal pockets inserted just beneath waistband at front lined with black cotton and white nylon; back plain except for two small darts; waistband fly and croch lined white nylon (now dyed blue).
Type: Length (jacket)
Height: 83 cm
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Hi, I am Jane from Want it, Need it, Quilt it! {www.quiltjane.blogspot.com} and today I am bringing you a sweet treat that has no calories.
Lollipop is a deliciously colourful collection from Sandy Gervias for MODA that I made into a child's snugly quilt or play mat. It would even make a cute wall hanging to brighten up a child's room.
This quilt is a simple project that can be pieced, quilted, and ready for snuggling in no time. Enjoy!
- 2 x Lollipop charm packs by Sandy Gervais for MODA
- 1/2 yard Brown Lollipop fabric for binding (#7521 444)
- 1 1/4 yards of Lollipop fabric for backing (# 17553 13)
- 40" x 40" piece of wadding
- 3.5" circle template
- Fusible webbing
- Embroidery Floss
Step 1 - Separate the solids from each charm pack.
Step 2 - Separate the remaining charm squares into groups of the same colours.
Step 3 - Choose one (1) charm square from each colour group with a small print. These will become the seven lollipops.
Step 4 - Place the circle template on the right side of your lollipop square and centre. Trace around it. Draw a freehand swirl on the right side of the square.
Step 5 - Using two (2) strands of embroidery floss, embroider the swirl design on each lollipop.
Step 6 - Iron fusible webbing to back of charm and cut out circle. Make seven (7).
Step 7 - Let's make the sticks for the Lollipops.
- Select some contrasting fabrics from the charm square pack
- Cut 1" strips from selected charm squares. The strip should measure 1" x 5"
- Fold 1/4 seam at one end of the strip
- Press the strip in half lengthways and open
- Press each long edge to the middle to form a stem 1/2" wide.
- Cut a 3/8" x length of stem of Fusible webbing. Iron on back of stem
Step 8 - Sew the same solid colour pairs together.
Step 9 - Place the lollipop and stick on the solid block, tucking the stick under the Lollipop. I measured 3/4" from the top and 3/4" from the bottom of the block. Iron the stick and Lollipop onto the block. Use you favourite technique to applique the Lollipop to the block. I machine appliqued the Lollipop with a neutral thread.
|There are many ways to applique - needle turn, fusible web - raw edge, machine applique or hand appliqued. It is really up to how you want the finished quilt to look - formal or naive.
Step 10 - Select random pairs from the remaining charm squares to make twenty five (25) blocks.
|I like to use a short stitch (2.5) and open my seams. If tension is correct, there should be no pulling apart of seams. Applying moderately dense quilting also helps to take the pressure off the seams.
Step 11 - Lay out the blocks like diagram below. Sew the blocks together to form rows and then join the rows
Step 12 - Layer the backing, batting, and quilt top. Quilt as desired. I used Perle 8 cottons and stitched around the Lollipops.
Step 13 - Cut four (4) x 2 1/4" strips from the width of fabric (WOF) to make binding. Attach binding to quilt.
Voila - You have completed the quilt! Now add a label, photograph it and give it to someone you love.
One hugly, snugly, delicious quilt.
Finished size of quilt 35" x 35"
Finished Block Size 4 1/2" x 9"
Jane Davidson


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Product Details
- Brand: Cavallini
- Contents: 5 Sticky note pads
- Size: Tin: 6 1/2 in. x 4 1/2 in. x 1/4 in.
- Packaging: Decorative tin
- Page Count: 96 notes per pad
- Other: Assorted pad sizes
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Sencha Superior
Item# VM_SENCHASUPERIOR
Product Info
Sublime first-flush tea with the flavor of sweet steamed greens.
Region japan
Product Details
Worthy of a special occasion, this is the finest first-flush Sencha, also called ichiban-cha or "number one tea." This tea has gentler, more intricate qualities than second-flush Sencha. Its process involves steaming the leaf, then rolling it again and again before drying it to form a spindly shape. The taste in the cup is bright, herbaceous and lightly sweet, with a mild astringency and good body.
How to Brew
For Best Brewing
- Use one heaping teaspoon of loose leaves per 8 fl oz of 215° water.
- Let it steep for 5 minutes. Wait patiently for perfection.
Green Tea
The liquor of a green tea is typically a green or yellow color, and flavors range from toasty, grassy (pan-fired teas) to fresh and streamed greens (steamed teas) with mild astringency.


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This page displays only a select list of music events.
Want to add Luther College Music Department events to your google calendar? Add this address: email@example.com and follow these instructions.
Sponsored by Music
Ms. Toomer received her Master of Music degree in Vocal Performance from the University of North Texas, and her Bachelor of Arts in Music from Luther College, where she also teaches applied voice, Class Voice, and Introduction to Opera. As an advocate for Czech and Slovak opera and art song, Ms. Toomer has performed across the globe, most recently in Náměšt' nad Oslavou, Czech Republic, and with the National Czech and Slovak Museum in Cedar Rapids, Iowa. In 2011, Ms. Toomer won the American semifinals of the Czech and Slovak International Voice Competition, and went on to compete in the international finals in Montreal, Quebec. She competed in the competition again in 2013, where she was a National Semi-Finalist and Encouragement Award Recipient. In addition to her teaching at Luther College, Ms. Toomer has also served as an Instructor of Voice Lessons and Vocal Performance Class for the Junior High Dorian Vocal Festival, and directed the Musical Theatre Workshop for the Senior High Dorian Vocal Festival.
Questions? Contact Kylie Toomer, 563-387-1209


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Attending a PHA on the Road forum is an exciting educational opportunity not to be missed. PHA provides a number of patient services during the event to help you manage your disease while you are away from home. Please consult with your physician about your travel plans.
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with Giuliano Hazan
Tour 10 of Italys most treasured sauces, and recreate them in under an hour with guidance from award-winning Italian cookbook author Giuliano Hazan. From spaghetti alle vongole and fettuccine Alfredo to linguine with basil pesto and more, youll explore the incredible flavors of authentic Italian dishes from every region. Braise squid and cook shrimp and scallops for a fresh seafood sauce, and learn two variations of irresistible pesto that you can make in under 10 minutes! Explore three luxurious cream sauces, plus master fundamental skills for prepping, dicing and sautéing an array of fresh vegetables for fettuccine alla primavera and spaghetti alla norma. Join Giuliano, and unlock the secrets behind 10 unforgettable sauces you can serve every night of the week!
Giuliano shows how to properly prepare a variety of seafood and shares his technique for peeling tomatoes as he makes two succulent sauces.
Learn which ingredients should be chopped and which ones to add during the final mix as you produce two perfect pestos: basil and walnut.
Giuliano shares the story behind the classic fettuccine Alfredo as he creates three delectable cream sauces, including gorgonzola and primavera.
No more mushy vegetables as Giuliano gives you tips for picking out the perfect eggplant and preparing tender broccoli rabe for two vegetarian delicacies.
Finish your study with this bonus lesson that features a late-night Roman favorite that includes garlic, olive oil and parsley.
Praise for Giuliano's Homemade Italian Pasta:
"I have been a student of Giuliano's for 20 years and have used his recipes and techniques at work and home with great success. I am a chef and love Italian food and if you love Italian food as I do and want to learn from one of the best, take one of Giuliano's classes. His food is truly authentic. He doesn't infuse any other cuisines when he teaches, which in my opinion is what makes it so good. Giuliano's the real thing."
- vcibotti31837525


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Did you know coyote mating season starts in December? The Edina Police Department does, and they are warning residents to prepare for an increase of activity in the coming months.
Police say the season will change in how the animals behave, and they, along with Animal Control, are urging residents to aggressively haze coyotes and keep an eye on their pets when outdoors.
According to Animal Control officials, coyotes may even target large dogs during the mating season, and could do significant harm to a family pet through pack hunting.
With no natural enemies in an urban setting, coyotes are free to come and go as the please.
"The thing about coyotes is we kind of have to learn to live with them," said Jason Abraham, with the Minnesota Department of Natural Resources.
According to Abraham, even fenced-in yards might not be enough to keep a pet safe when coyotes are more active.
"It might see [the pet] as a predator, it might see it as competition for food," he explained.
Abraham says that's why homeowners need to be as territorial as the coyotes are to keep the critters from becoming either a nuisance or a risk.
Any resident who sees a coyote on their property is urged to shoo away the coyotes using the following tactics:
Residents are also encouraged to keep garbage cans closed securely to avoid attracting coyotes or other wildlife, such as raccoons or possums.
Typically, the coyote mating season runs through March.
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New Nanotech Design Improves Drug Efficacy, Lowers Toxicity
Researchers at the Massachusetts Institute of Technology (MIT) and Brigham and Women's Hospital have revealed a nanoscale molecular design that increases the efficacy of the chemotherapy agent docetaxel against prostate tumors while reducing its toxic side effects in mice. The study, which appeared April 18 in the Proceedings of the National Academy of Sciences and was funded in part by NCI, is the first case where aptamers - short strands of nucleic acids - have been used successfully for the targeted delivery of a cancer drug in vivo.
"The greatest advantage of our study is in the combination of materials that we used," says Dr. Robert Langer of MIT, who directed the project with Dr. Omid Farokhzad of Harvard Medical School. Their team chose prostate cancer because it is often diagnosed early, when treatment prognosis is good, hoping that a need for safer localized treatments may facilitate the translation of their work to patient care. They designed their drug-delivery vehicle from poly (D,L-lactic-co-glycolic acid) (PLGA) because of the material's demonstrated safety in other FDA-approved medical devices, such as sutures. Read more
Promoting the Development and Delivery of Targeted Therapies
Earlier this month at the American Association of Cancer Research annual meeting, impressive data were presented from a phase II trial testing the multitargeted kinase inhibitor dasatinib (BMS-354825) in patients with chronic myeloid leukemia (CML) who had failed to respond to or had developed resistance to imatinib (Gleevec). In chronic-phase CML patients, for instance, 93 percent had a complete hematologic response, meaning normal blood counts and no CML-related symptoms.
Imatinib has rightfully been heralded as a breakthrough drug. Dasatinib is an excellent example, though, of how cancer researchers are learning from the successes and failures of targeted therapies like imatinib to make important advances in the development of next-generation targeted agents. Not only does dasatinib have a 325-fold stronger affinity for its gene target, BCR-ABL, than imatinib, it also appears to be effective against 18 of the 19 identified mutated forms of BCR-ABL - the very mutations that drive imatinib resistance. Read more
New Nanotech Design Improves Drug Efficacy, Lowers Toxicity
Researchers at the Massachusetts Institute of Technology (MIT) and Brigham and Women's Hospital have revealed a nanoscale molecular design that increases the efficacy of the chemotherapy agent docetaxel against prostate tumors while reducing its toxic side effects in mice. The study, which appeared April 18 in the Proceedings of the National Academy of Sciences and was funded in part by NCI, is the first case where aptamers - short strands of nucleic acids - have been used successfully for the targeted delivery of a cancer drug in vivo.
"The greatest advantage of our study is in the combination of materials that we used," says Dr. Robert Langer of MIT, who directed the project with Dr. Omid Farokhzad of Harvard Medical School. Their team chose prostate cancer because it is often diagnosed early, when treatment prognosis is good, hoping that a need for safer localized treatments may facilitate the translation of their work to patient care. They designed their drug-delivery vehicle from poly (D,L-lactic-co-glycolic acid) (PLGA) because of the material's demonstrated safety in other FDA-approved medical devices, such as sutures.
To help the vehicles find their targets, the team coated their surfaces with aptamers that bind to a membrane protein found on prostate cancer cells. Aptamers have an advantage over antibody-targeted systems because they can be manufactured independently of biological systems, with less variability. The team added polyethylene glycol to the surface, helping the particles resist the body's efforts to break them down and flush them out. Dr. Farokhzad describes the resulting bioconjugates as "very small tennis balls - small enough that you could put 500 of them side-by-side to span the cross section of a piece of human hair - with molecules on the surface that look like pins."
The addition of aptamers to these nanoparticles gave promising results: in vitro, the bioconjugates killed about 30 percent more tumor cells than when docetaxel was given via aptamer-free particles. When mice xenografted with prostate cancer were given just one injection of the bioconjugate at their tumor site, their lesions shrank significantly, and in five of seven mice, the tumors disappeared within 6 weeks. Mice in the comparison groups saw less shrinkage and, in some cases, died.
All of the mice that received the bioconjugates survived the full length of the 109-day study and also maintained their body weight better than those that received straight docetaxel, indicating that the bioconjugate design may have shielded them from toxic side effects of the drug.
"The real advantages here are that the design gets the drug to the right place, and appears to avoid the toxicities and metabolic effects that have hampered some chemotherapy agents up to this point," says Dr. Gregory Downing, director of NCI's Office of Technology and Industrial Relations.
Dr. Farokhzad's group plans to continue their research with aptamer bioconjugates in larger animal models, and he projects human clinical studies in as little as 2 years. His team is pursuing bioconjugates that target atherosclerotic plaques for treatment of cardiovascular disease as well. Other research with aptamers has shown that they can be used to carry imaging agents, which may eventually be used to visualize the location and concentration of drugs at the subcellular level.
By building their bioconjugates from material known to be safe in humans, Dr. Downing says the MIT-Harvard researchers may have an advantage when it comes to eventual clinical testing and regulation. "But there are quite a number of questions that will need to be addressed," he says.
"At the nanoscale level, the fundamental properties of materials change," he continued. "The laws of pharmacokinetics are redefined, and the ability of these things to transfer across biological membranes, self-assemble, or take over molecular functions isn't really known yet."
This research was conducted in laboratories that are funded as the MIT-Harvard Center of Cancer Nanotechnology Excellence, part of NCI's Alliance for Nanotechnology in Cancer initiative that accelerates the application of promising nanotechnology to cancer.
By Brittany Moya del Pino
Promoting the Development and Delivery of Targeted Therapies
Earlier this month at the American Association of Cancer Research annual meeting, impressive data were presented from a phase II trial testing the multitargeted kinase inhibitor dasatinib (BMS-354825) in patients with chronic myeloid leukemia (CML) who had failed to respond to or had developed resistance to imatinib (Gleevec). In chronic-phase CML patients, for instance, 93 percent had a complete hematologic response, meaning normal blood counts and no CML-related symptoms.
Imatinib has rightfully been heralded as a breakthrough drug. Dasatinib is an excellent example, though, of how cancer researchers are learning from the successes and failures of targeted therapies like imatinib to make important advances in the development of next-generation targeted agents. Not only does dasatinib have a 325-fold stronger affinity for its gene target, BCR-ABL, than imatinib, it also appears to be effective against 18 of the 19 identified mutated forms of BCR-ABL - the very mutations that drive imatinib resistance.
It is this latter observation concerning overcoming the problem of acquired resistance to molecularly targeted therapies that I find most intriguing. From our work on CML resistance to imatinib, and several other molecularly targeted therapies, it appears that the cancer cells become resistant to therapy by the development of further mutations in the targeted pathway and not by mutations or genetic alterations occurring as random events in any critical signaling pathway within the cancer cell. The importance of this, if it holds to be true, is a tremendous economy of scale allowing investigators to focus the study of developing resistance on the original pathway.
Even with the interest and optimism generated by these initial targeted therapies, we must acknowledge that this is a field very much in its infancy. NCI is engaged in efforts on many fronts, intramurally and extramurally, to accelerate the progress in this area. NCI intramural researchers, for example, are identifying important new molecular targets and utilizing high throughput screening of chemical and natural product libraries, developing drugs that inhibit them. Among these is 17-DMAG, a second-generation inhibitor of heat shock protein 90, that has the potential to treat many tumor types.
But NCI's involvement in targeted therapy research goes beyond the work of individual NCI labs or researchers. It is remarkably comprehensive and involves collaborations and partnerships in areas such as molecular imaging, toxicology, drug design, and early phase clinical trials supplemented by intense correlative studies.
One example is the Molecular Targets and Molecular Oncology Center of Excellence, a multifaceted effort that brings together intramural and extramural labs. Through this program we are working with private-sector companies to bring new molecularly targeted screening-platform technologies to NCI. As a result, we already have launched individual projects to screen millions of compounds to determine if they have activity against new molecular targets.
NCI's Cancer Therapy Evaluation Program (CTEP), meanwhile, has had great success working with industry to test combinations of targeted agents. While targeted agents are powerful in their own right, the research community and industry agrees that combining targeted agents will greatly increase their efficacy, and in fact may be essential. To date, CTEP has begun some 100 clinical trials featuring combinations of targeted agents, most of which have been started in the past 2 years.
Finally, through partnerships with extramural investigators, industry, and other private entities in the areas of screening, imaging, and preclinical pharmacology, we are moving to formalize a cancer therapeutics development consortium. Through this partnership we will conduct the so-called phase 0 studies to facilitate rapid screening of new targeted agents in humans before taking them into more full-scale development. The program also will launch a new national clinical target validation lab to find new ways to analyze the effects of small-molecule anticancer drugs.
NCI has made a major commitment to supporting the development of genomic and molecular assays to identify the patients most likely to benefit from a particular therapy regimen. As cancer researchers become more adept at developing molecular profiles of individual patients' tumors, we will ensure that many more patients receive a treatment with the best chances of success. This is the true promise of molecularly targeted therapies.
Dr. John E. Niederhuber
Natural Killer Cells Power Immune System Response to Cancer
Targeted treatments and immunotherapy are two of the most promising approaches to cancer, and each may one day be transformed by basic research on natural killer (NK) cells.
Stem cells in the bone marrow produce most of the immune system's components, including the white blood cells known as lymphocytes. Between 2 and 20 percent of these are NK cells, specialized lymphocytes that continuously patrol the body, eliminating cells that undergo malignant transformation.
Natural killers are aptly named because they act like commandos on a search-and-destroy mission for virally infected and cancerous cells. This streamlined, "ready-to-go" role for NK cells is part of the innate immune system "and makes them well suited for an early defense," explains Dr. Mary Carrington, director of NCI's Basic Science Directorate of NCI's Center for Cancer Research (CCR) in Frederick, Md.
An emerging view of carcinogenesis suggests there is often a long, silent, precancerous period where normal cells begin to undergo alterations, leading eventually to clinical disease. It would make sense if the immune system recognized these threats earlier, when they are easier to combat. "NK cells may have evolved, in part, for this very task," says Dr. Carrington.
How do they do it? Patrolling NK cells first lock onto potential target cells. Then a number of receptors search for complementary molecules on the target. Each receptor finding a match sends an internal signal, which varies not only in its basic message - destroy or ignore - but also in its strength. If the final message says "destroy," the NK makes holes in the target's membrane with the protein perforin, enabling enzymes to enter and destroy the cell's DNA.
Scientists such as Dr. Stephen Anderson, senior principal investigator at NCI-Frederick's Laboratory of Experimental Immunology in CCR, are trying to learn more about how a single cell can make such a complex sequence of calculations and judgments.
In mice, where most experimental work is done, the job of recognizing "self" falls to the Ly49 family of receptors. In humans, killer cell immunoglobulin-like receptors perform this function.
"We have identified a large number of Ly49 inhibitory receptor genes in mice, but a given NK cell does not express them all," explains Dr. Anderson. "The gene for each of these receptors has a unique DNA switch, which turns some 'on' and others 'off' in a random fashion. Thus individual NK cells become 'specialists,' trained to recognize only certain types of threats." The variety of receptors expressed across the population of patrolling NK cells will recognize a number of viruses, as well as signatures characteristic of cancer cells.
Though now a very promising area of immunology and cancer research, two decades ago NKs were under-appreciated, often referred to as "null" cells. But a few scientists, such as Dr. Klas Kärre of the Karolinska Institute in Stockholm, saw them as a black box that should be unlocked. The breakthrough idea emerged in 1986 and is now known as the "missing-self" model.
"In vertebrates, nearly all cells express glycoproteins known as HLA Class I, the genes for which are highly variable across the population," explains Dr. Carrington, whose lab has helped fill in the HLA picture. Yet they produce a signature common to all cells within each individual. In the clinical context, this pattern confers a person's tissue type, a crucial factor in whether a transplanted organ will be rejected. Insights from NK cell research may one day lead to more successful bone marrow transplants.
When NK cell inhibitory receptors that recognize "self" detect a person's own HLA on a cell, the basic message: "This one is us and healthy, let it be!" usually prevents the destruction of the cell. Not coincidentally, many cancer cells have downregulated these "self" proteins and are thus recognized as prime targets for destruction.
"The 'missing-self' hypothesis was brilliant and foresighted, but we have been able to refine it in several important ways," says Dr. Lewis Lanier, professor and vice chair of the Department of Microbiology and Immunology at the University of California, San Francisco.
"When NKs and potential target cells meet, we now see the inhibitory receptors acting more like a dimmer switch than an on-off switch. Information is interpreted by an analog, not a binary process," he explains. The cell essentially combines signals from a number of inhibitory and activating receptors to arrive at the final destroy-or-ignore decision.
Over time, NK cells have waged a kind of war with viruses in the body. NK cell receptors have evolved to recognize specific molecules that mark certain cancer signatures and viruses, such as human cytomegalovirus.
But viruses - and no doubt some cancers - also persist by evolving to outsmart the immune system of their potential host, and "some of the more deadly cancers have also evolved a way to silence the genes coding for the proteins recognized by NK cell activating receptors," suggests Dr. Lanier.
A few years ago, with NCI support, Dr. Lanier's lab identified molecules that are preferentially expressed on tumors for an important activating receptor known as NKG2D. Certain cancers may have evolved a way to turn off genes that encode for these molecules, and thus deceived the NK cell. "If we could develop ways to turn these genes back on, we would be much closer to a vaccine for cancer," says Dr. Lanier.
By Addison Greenwood
Prostate Cancer Risk Calculator Available Online
Researchers have developed an online statistical tool for estimating an individual's risk of developing prostate cancer. The risk calculator is designed to help certain men and their physicians evaluate the potential risks and benefits of being screened for prostate cancer. It is available at http://www.compass.fhcrc.org/edrnnci/bin/calculator/main.asp.
The calculator takes into account prostate-specific antigen (PSA) testing, family history, rectal examinations, and history of a prior negative prostate biopsy. Though PSA testing is widely used to assess prostate cancer risk, it does have limitations. Men with normal PSA levels can develop prostate cancer, while some men without prostate cancer can have abnormal levels.
"This risk calculator model uses variables that go beyond only PSA level to help patients and physicians decide whether a prostate biopsy should be performed," write Dr. Ian Thompson, of the University of Texas Health Science Center at San Antonio, and his colleagues in the April 19 Journal of the National Cancer Institute (JNCI).
The calculator was developed using data from 5,500 men in the placebo group of the Prostate Cancer Prevention Trial; it is appropriate for men age 55 or older who have had recent PSA testing and rectal exams but no history of prostate cancer. The researchers say that the calculator improves the accuracy of PSA testing, but the use of PSA testing alone in prostate cancer screening has yet to be shown to save lives.
"The hope is that the risk calculator helps us do a better job selecting patients for biopsy," says co-author Dr. Howard Parnes of NCI, adding, "We need to be careful about how we apply the test." He raises the possibility that the calculator could lead to a large increase in the overall number of biopsies. This, in turn, could increase the overdiagnosis and overtreatment of the disease by detecting and treating cancers that would never have come to clinical attention were it not for screening.
A JNCI editorial discusses the critical need for accurate biological markers associated with life-threatening prostate cancer. "Once we have the ability to assess multiple risk factors in populations for which the long-term outcomes are known," approaches like the risk calculator will help identify those men who will benefit from active treatment, writes Dr. H. Ballentine Carter of the Johns Hopkins School of Medicine.
Elderly Female Cancer Survivors Face Functional Limitations
Elderly cancer survivors face quality-of-life issues that currently are not well understood. A large population-based cohort study published in the April 19 JNCI sought to clarify the limitations in daily activities faced by older women who have undergone cancer treatment.
In 1986, the Iowa Women's Health Study originally accrued 37,233 postmenopausal cancer-free women who were then followed for cancer occurrence through a link to the regional Surveillance, Epidemiology, and End Results cancer registry. Through a follow-up questionnaire, limitations in daily activities such as walking, housework, or meal preparation were assessed in 1997 for both cancer survivors and women who never had cancer.
Cancer survivors were divided into three postdiagnosis categories for analysis: less than 2 years, between 2 and 5 years, and 5 or more years. Other factors known to be associated with functional limitations, such as smoking, body mass index, and some chronic medical conditions, were included in the analyses.
Women returning the questionnaire less than 2 years after a diagnosis of cancer were significantly more likely to report functional limitations than women who never had cancer. Between 2 and 5 years after diagnosis, women were significantly more likely to report some but not all of the limitations listed on the questionnaire than women who never had cancer. Women who had been diagnosed more than 5 years previously were significantly more likely to report limitations in activities requiring strength and mobility than women who never had cancer.
The investigators conclude that "these findings support the need for interventions to prevent and reverse functional decline among elderly long-term cancer survivors." In an accompanying editorial, Drs. Julia Rowland and Rosemary Yancik from NCI's Office of Cancer Survivorship stress the need for incorporation of quality-of-life interventions into all stages of cancer treatment. They note that, "…with growing numbers of cancer survivors living 5 or more years after their diagnosis, the scope of quality cancer care must broaden beyond the limited focus on cure to one that fosters health promotion and minimizes dysfunction or disability after illness."
Parents Need Help Talking to Children about Their Cancer
"I thought that before…there was no cure from it; that you just died basically." That's what a 10-year-old girl said to British researchers about her mother's breast cancer diagnosis. After conducting the study about communication between children and a parent with cancer, the researchers concluded that parents diagnosed with cancer would likely benefit from support and assistance in talking with their children about their situation.
In the study, an early online release in the British Medical Journal, Dr. Alan Stein and colleagues from Oxford University also found that the children in the study - who ranged in age from 6 to 18 - often already suspected or knew something was wrong before their parents finally told them about the cancer, and many of the children over 12 wanted more information about it than they got from their parents.
The research team conducted home-based interviews about family communication with 37 women diagnosed with breast cancer being treated at a single cancer center. They then conducted interviews with the women's children (31 altogether) about their experiences with their mothers' illness.
Many children found it especially distressing to see the effects of chemotherapy on their mothers, the researchers found, and also had wildly different interpretations of what the different treatments their mothers were undergoing actually meant for their prognosis.
"Parents are often unaware how much their children know and, often reeling from the diagnosis themselves, may not be in the best position to decide what and how to tell them," the researchers wrote. Families "may need considerable help in dealing with communication…and determining how support could be provided for their children as well as themselves."
More information on communicating with children about a parent's cancer is available from NCI and the American Cancer Society.
Announcement Number: PAR-06-294
New Application Receipt Dates: July 20, 2006; Nov. 20, 2006; March 20, 2007; July 20, 2007; Nov. 20, 2007; March 20, 2008; July 21, 2008; and Nov. 21, 2008.
This is a renewal of PAR-04-159 and will use the R03 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3405. Inquiries: Dr. Mukesh Verma - firstname.lastname@example.com
Mechanisms of Alcohol-Associated Cancers
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3392. Inquiries: Dr. Sharon Ross - email@example.com
Mechanisms of Alcohol-Associated Cancers
This funding opportunity will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3393. Inquiries: Dr. Sharon Ross - email@example.com
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk
This is a renewal of PA-05-059 and will use the R21 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3395. Inquiries: Dr. Cindy D. Davis - firstname.lastname@example.com
Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery
This funding opportunity will use the R01 award mechanism. For more information, see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=3397. Inquiries: Dr. Louise Wideroff - email@example.com
Immunotherapy for Advanced Pancreatic Cancer
Name of the Trial
Principal Investigator
Why This Trial Is Important
During an immune response, cells signal each other in complex ways that serve to start, stop, or control the intensity of the response. Molecules found on many types of cancer cells stimulate certain immune system cells (called cytotoxic T lymphocytes, or activated T cells) to attack the cancer cells. Once the attack has started, however, the activated T cells produce a molecule called cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4). This molecule then produces a signal that tells the T cells to stop their attack. This T-cell inhibition helps prevent normal cells from being harmed by an immune response, but it may also prevent the immune system from destroying malignant tumors. Researchers hope that blocking CTLA-4's inhibitory signal will lead to a more robust immune response against tumors.
In this trial, researchers are using a monoclonal antibody called MDX-010 to treat patients with advanced pancreatic cancer. MDX-010 binds to and blocks the activity of CTLA-4.
"We know that T lymphocytes infiltrate pancreatic tumors in great numbers, but the tumors present an immunosuppressive environment," said Dr. Royal. "We hope that MDX-010 will help lymphocytes overcome this immunosuppression and allow the patient's own immune system to destroy their cancer."
Who Can Join This Trial
Contact Information
An archive of "Featured Clinical Trial" columns is available at http://cancer.gov/clinicaltrials/ft-all-featured-trials.
NCI CAM News, a new biannual newsletter produced by NCI's Office of Cancer Complementary and Alternative Medicine, features the latest news on NCI's complementary and alternative medicine (CAM) activities. Content includes highlights of NCI-sponsored CAM research; resources for researchers, such as funding opportunities and grant-writing workshops; upcoming meetings and lectures; and information about CAM modalities for cancer. The free newsletter is available online at http://www.cancer.gov/cam/news.html. To subscribe, go to https://list.nih.gov/cgi-bin/wa?SUBED1=nci_cam_news&A=1.
Breast Cancer Video Available
Most women finishing breast cancer treatment are eager to put the cancer experience behind them and get back to normal. However, the time immediately following treatment can be particularly difficult, with a wide range of emotions and reactions.
The 23-minute video features vignettes of women in different life stages who share their concerns and experiences about body changes, emotions, relationships, and new perspectives. Breast cancer surgeon Dr. Susan Love also provides medical insight on common reactions of breast cancer survivors in each of these areas.
The video was funded by an NCI grant to the UCLA School of Public Health and the Jonsson Comprehensive Cancer Center. The Susan G. Komen Foundation provided funding for a portion of duplication and distribution costs. Copies in VHS or DVD formats are available by contacting NCI's Cancer Information Service toll free at 1-800-4-CANCER (1-800-422-6237) or online at https://pubs.cancer.gov/ncipl.
NCI Staff Win Plain Language Awards
Nearly a quarter of the winning entries this year were written by NCI staff. Two projects won Outstanding Awards: "Graphic Standards for Use of NCI Logo," by Donna Bonner, Paul LaMasters, Malka Scher, Walt Burroughs, Del Harrod, Kathryn Hollen, Elizabeth Johnson, and David Fridberg; and "When Cancer Returns," by Louise Cunningham, Lori Keesey, Susan Spangler, Rhonda DeJoice, and Melinda Moyer.
Excellent Awards went to: "NCI Office of Communications Orientation Resources," by Robyn Bason, Cheryl Burg, Ilene Burstyn, Kevin Broun, Nina Ghanem, Tanisha Gregory, Cindy Lollar, Sahil Malik, Henry Ostapiej, Nicole Saiontz, and Valerie Secker; and "Understanding Cancer," by Donna Kerrigan, Miguel Monroy, and Jeanne Kelly. Seven other NCI projects received Honorable Mention awards.
Southeast Cancer Control Consortium, Inc., CCOP
Principal Investigator: Dr. James N. Atkins • Administrator: Susan Tuttle, RN, CCRP • SCCC Operations Office, 2150 Country Club Road, Suite 200, Winston-Salem, NC 27104 • Phone: 366-777-3036 • Web site: http://www.southeastcancercontrol.org
SCCC includes 122 physicians, among them oncologists, surgeons, urologists, and radiation oncologists. Its operations office is located in Winston-Salem and is staffed by five employees who oversee the daily functions of the program.
SCCC's mission is to offer clinical trials aimed at cancer prevention and control in the communities it serves, thus improving the quality of cancer treatment, reducing incidence through education, and reducing morbidity and mortality through early diagnosis.
Community Characteristics
Recruitment and Outreach Activities
Accrual to clinical trials for minority populations is challenging, but on average, SCCC achieves a 15-percent minority enrollment for its trials. Minority nurse recruiters have been used in several communities to provide cancer education and promote clinical trial research.
In addition to its funding as an NCI CCOP, SCCC collaborates with eight NCI-funded clinical trial cooperative group research bases, including the National Surgical Adjuvant Breast and Bowel Project, for which it is the highest accruing CCOP for treatment studies; the Cancer and Leukemia Group B, for which it is the second-highest accruing CCOP overall; and the Southwest Oncology Group, in which SCCC recruits patients for cancer-treatment and cancer-control studies. Other research affiliations are with the Radiation Therapy Oncology Group, the Cancer Trials Support Unit, the University of Rochester Cancer Center, the University of Michigan Cancer Center, and the Comprehensive Cancer Center of Wake Forest University. SCCC receives its clinical trial protocols and processes the resulting data through the eight research bases; patients are recruited to clinical trials through the CCOP itself.
Other Key Facts
This year, Dr. Atkins was recognized for his outstanding contribution as a community investigator by the Association for Community Cancer Centers, and in March, he received the NCI Harry Hynes Award for outstanding dedication and commitment in bringing clinic trials to the community.


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Jennifer's Q & A
Who's your favorite sports team, and why?
My favorite sports team is the Oakland raiders. I know they aren't the best team in the nfl, but I stand by them. I was a cheerleader for the Oakland raiderettes in 2009 & that's where I especially grew to love the team & the fans.
What's your favorite movie quote?
"You can't live your life for other people. You've got to do what's right for you, even if it hurts some people you love." ― Nicholas Sparks, The Notebook
What's your favorite video game, and could you kick our butts at it?
X box dance central. & yes I could probably kick your butts at it :)
Piercings/Tattoos (How many? Where?)
Piercings: 2 on each earlobe, 1 on each trigis, & my tongue Tattoos: 1 on my ankle of plumeria flower & "kulia I ka nu'u" & one on my forearm saying "c'est la vie"
What's the most embarrassing song on your iPod?
To be honest, my computer crashed & I got a new iPhone so I actually have no songs on my iPod. Buuuuut if it were to be anything it would probably be an old Christina aguilara song.
What's your best party trick?
Not much of a party trick kind of person, but I love to do keg handstands lol
What's the most memorable pick-up line you've ever heard?
Most of them I've heard are always horrible & I end up walking away from the guy so I never really remember them. Just the fact that they were really dumb
What's the worst job you've ever had?
The worst job I ever had was when I was 17 & I worked at a soul food restaurant in my hometown.
What's the most dangerous thing you've ever done?
I'd have to say when I was younger I was a lot more dangerous until I hurt myself dirt bike riding. Now I definitely think of the outcome before I try anything dangerous lol
It's 4AM after a crazy night out – what are we eating?
My guilty pleasure....McDonald's!! Lol
What's the strangest thing in your fridge right now?
An artichoke, because I never eat them but wanted to cook it one day. I still have yet to do that. It's probably gone bad now lol
What's the naughtiest thing you've ever done in public?
Hehe.....got down and dirty at a children's playground
What do you feel sexiest wearing?
Sexy lingerie duh! Preferrably red or black maybe a print of both colors combined. & sexy stilettos ;)
Tell us a joke.
A mother is making a cake for her three sons when she accidentaly dropps some BB from the shelf into the batter. She decides that it won't matter and continues to make the cake. Later that day, her sons eat the cake and don't even notice the BBs. The next day, when the mother is reading a magazine on the couch, one of her sons runs in saying, ''Mom, mom, I pissed out a beebee!'' She says ''That's okay, son. I accidentaly dropped some beebees into the cake batter. You'll be fine.'' Five minutes later, one of the other sons, come running in and he says, ''Mom, mom, I-'' but the mother cuts him off and she says, ''I know, I know, you pissed out a beebee. I dropped it into the cake batter, but you'll be fine.'' Then her last son runs in the room, and he says, ''Mom, mom, I-'' and the mother cuts him off and says, ''I know, I know, you pissed out a beebee. It's my fault for dropping it in the cake batter, but you'll be fine.'' But then son says, ''No, no, I was masturbating and I shot the dog!"


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NCI Named One of the Best Places to Work for Postdocs
NCI ranked 13th on The Scientists' 2012 Best Places to Work for postdocs. Career development opportunities are one of the institute's strengths, according to the journal's 2012 survey. For information about training opportunities at NCI, visit the Center for Cancer Training website.


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Like Mandy, my sister & I were actually pretty egged on by my parents to make "customizations" to our toys. Remember those monkeys with holes in their ears/mouths/noses that you could then stick their thumbs/toes into? My mom was pleased to find one with rearranged limbs (as in legs jutting out of arm sockets) after my sister and I performed a morbid bit of surgery on one of them with scissors and safety pins. Guess that got me started with my love of reconstruction early on in life. Oh, and we had a creepy life-sized Barbie head without a body that you could style with makeup and curlers. She looked really punk rock by the time we were done with her.
You guys are bringing back all kinds of memories of make-believe games my sister & I would play as kids. I remember getting a microcassette recorder one Xmas ("you'll want to remember all those story ideas that come into your head", said Mom). Anyway, my sister and I staged these mock presidential elections between my monkeys and recorded "interviews" with them. One was in cowboy get-up, the other in tennis gear. The latter spoke like Ricky Ricardo and hailed from the Republic of Cocarita before immigrating to our fictitious country. The cowboy talked like a cross between Yosemite Sam and Porky Pig. Even back then, it was a race between the populist of color and the elitist good 'ol boy who fought dirty to win the election. At one point, the cowboy confided to his interviewer that he planned to "kill that little Cocarita boy " if he won the election. What was even more fun was the fact that my sister didn't catch that part until we later played it all back. She was shocked and horrified, much to my delight. Hee!
Gwenn, I'll bet my hubby would love to read your dad's article. He was on a team that designed audiophile speakers. Share it?


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Well, I fell today. I was out snooping around our "back woods" area near the lake, and tripped over something that I did not see. Went down so hard it must have caused earthquake monitors to jump wildly.
Right now...after about 4 hours...my knee is throbbing and my shoulder aches. No problem...they will be fine in a week or so.
It just so happens that it is the same knee that took a major hit the last time I fell...4-5 months ago. The stairway was involved that time.
Moral of story:
Either don't fall so often...or, look for softer places to land.


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Welcome to the Artist section of the Decca Website
Choose an artist from the left side of this page - either via a photo or the dropdown menu.
Wins recording of the Year plus Orchestral and Vocal Awards
American cellist Alisa Weilerstein was yesterday named winner of the BBC Music Magazine Recording of the Year Award with her debut concerto disc of the Elgar and Carter Cello Concertos with the Berlin Staatskapelle and Daniel Barenboim on Decca.
Alisa Weilerstein's recording was voted for by both the public and BBC Music Magazine's expert jury and was chosen as the best of more than 1,500 reviewed by the magazine in 2013.
The awards jury said: "Weilerstein avoids nostalgia and produces an account full of passion, grief and nobility of feeling … it's been years since a new recording of Elgar's great concerto made this kind of visceral impact."
Alisa Weilerstein signed an exclusive contract with Decca Classics in 2011. Her winning recording has been widely feted, the New York Times acclaiming "the soloist's superb control keenly matched by the conductor's insightful support".
Riccardo Chailly's recording of the Brahms symphonies with the Gewandhaus Orchestra won the Orchestral Award ("Chailly combines fiery athleticism with the warmly blended tonalities of the wonderful Leipzig orchestra. The results tingle with immediacy and a pulsating sense of momentum") and the Vocal Award went to Jonas Kaufmann's disc of Wagner arias with the Orchester der Deutschen Oper Berlin conducted by Donald Runnicles ("No other Heldentenor can touch Kaufman in this repertoire: radiance, refinement and expressive eloquence mark out these magnificent performances of narrations and lieder"), both on Decca.
The winners were announced yesterday at an exclusive awards ceremony held at Kings Place, London.


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Children with a statement of special educational needs
Children with a statement of special educational needs
We believe that children and young people with learning difficulties should be welcomed and educated in their local mainstream primary school. This is where the majority of these children are educated. To meet the needs of children and young people in their local community benefits them both academically and socially.
We have teams of specialists who are available to work with teachers in mainstream primary schools in developing individual programmes of help and support for children experiencing problems. We are supporting all schools in using the Standards for Inclusion. If you as a parent, or the Headteacher or a member of staff in your child's school, feel that your child has special educational needs and may require additional help, talk to the Special Needs Co-ordinator (SENCo) at the school.
The Special Needs Co-ordinator has regular contact with specialist teachers and psychologists who can work with the school to gain a better understanding of your child's learning needs and to develop teaching approaches that will meet them.
Starting Reception Class in September 2015
Any child with a Statement of Special Educational Needs is required to be admitted to the school that is named in their statement. This gives any such child overall priority for admission to the named school.
The Special Educational Needs Assessment and Review Service is responsible for allocating reception places and amending statements of children with a Statement of Special Educational Needs.
Please be aware that where only one twin has a Statement of Special Educational Needs, and a school is named in their statement, this does not give the other twin an automatic sibling claim. This is because the twin with the statement is not due to start the named school until September 2015.
If you have any queries please contact the SEN Assessment and Review Team:


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The Danger of E-Fences
Texas dog picked up by animal control despite e-fence
Please note comments are moderated. After being approved your comment will appear below.
In the summer, I walk my leashed dog in a neighborhood with lots of e-fenced dogs. Many of them are fence runners, barking frantically to get at us. Even though they seem to respect exactly where the boundary is, I'm always afraid that one of them will burst through. I've also thought it was a shame that, if friendly, the dogs could sniff noses through a chain-link (for example) fence. Not the case for e-fenced dogs! I also wonder about theft. Personally, I would never consider e-fencing.
It's a tough decision really. I don't currently have an E-fence, but I live in a duplex where we have an enormous yard that to fence would be near impossible, and mostly a waste of money. It seems like such a waste to have all that space yet not be able to let my pup run free. She has a really long lead but still.
Submitted by Virginia | November 19 2010 | Permalink
The problem I find is that dogs in electric fences will cross the boundary if there is something interesting enough to motivate them, and then be afraid to cross back in.
I was walking my dog yesterday when a neighbor's dog crossed the E-fence line and started following us, but was walking in the middle of the street. Every so often I would stop walking and he would head back home, but he'd stop short at the line to cross back into the fence line. Finally I used some training treats in my pocket to get him to cross back over, but it was stressful and dangerous for him to be wandering in the street like that.
His owners weren't home.
Submitted by Anonymous | November 23 2010 | Permalink
I'm not a fan of the e fence. As a trainer I find that it can lead to all kinds of behavior issues. But if one does need to use an e fence, the dog should never be left unattended.
Submitted by Kachadurian | November 23 2010 | Permalink
My dog, Bissell grew up in a small lot with a fence. When we moved out of the city he was much happier when he ran free in our large wooded lot. Our new home was in a rural area with very few and dog-friendly neighbors and almost no traffic. He played with other neighborhood dogs. All was good until something happened. My dog came home with a cut on his shoulder and a lead pellet in his back.
After I got over the initial rage that one of my neighbors would take a shot at a friendly 20 pound dog rather than just giving me a call, I decided it was time to keep him in the yard.
There were three choices: leash, fence or e-fence. Life on a tether is no life at all for an active dog. I could have put up a fence for the small part of my yard that has a lawn and restricted him to watching the woods he once played it.
For a little over $1,000 I was able to put an e-fence around my entire one acre. I was so torn about the shock notion that I insisted on doing all the training myself. Bissell's a fast learner and trusts me to give him good advice, so after only two shocks, when I told him "careful" he knew exactly where his limit was. In two years now he's activated the fence only twice (once running after a deer that wandered by our yard). With a regular fence my children would have left the gate open more often that that.
The e-fence has become so much a part of his routine that when we get home from a walk outside the fence with his non-electric collar he waits until I change him into his e-collar before he bounds up the hill to see if anything changed in our yard while we was gone.
He is a safe and happy dog now. He can sleep in the sun on the driveway. He can chase chipmunks into the woods. He can play outside with my children. He has hills to wander up and down.
The key to an e-fence is the same as anything else with a dog. It's your responsibility to make it work. Good training and a concern for your pet's well-being are all it takes.
Submitted by Mark Heber | December 4 2010 | Permalink
There are places where electronic fences are useful and appropriate but an urban environment is not one of them. In a rural area or on a camping trip with well trained dogs, the invisible fence can be useful but for full-time containment in the city or the country, a fence is the best way to keep your dogs safe and safely on the property.
More From The Bark
More in JoAnna Lou:
Copyright © 1997-2014 The Bark, Inc. Dog Is My Co-Pilot® is a registered trademark of The Bark, Inc


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Bugsy Siegel
On 'Boardwalk,' Meyer Lansky Looms Large
The ruthless Jewish gangster is all business on the Prohibition-era HBO show
In Las Vegas, a Family Goes to Court Over Decision To Shutter Failing Newspaper
Brian Greenspun is suing to stop his siblings from undoing the legacy of their father, Hank, founder of the 'Las Vegas Sun'
App Lets You Atone From Your Smartphone9:37 AM —
Inspired by Leviticus, eScapegoat lets users offload sins onto a virtual goat
U.K. Store Security Guard Tells Boys 'No Jews'7:23 PM —
The 11-year-olds were wearing uniforms of local Jewish secondary school
On Martha's Vineyard, the Jews are WASPs too6:17 PM —
An excerpt from Lucinda Franks' Timeless: Love, Morgenthau, and Me
In Israel, September is Nobel Season3:44 PM —
Predicting which Israelis will win the esteemed award is a national pastime
Streisand on Israel: The World Envies Success2:58 PM —
The singer also attributes past bad press to anti-Semitic and anti-female bias
Ongoing Controversy Around 'The Most Important Story on Earth'12:29 PM —
Responding to critics of my essay about Israel media coverage
A Fashion Week Bat Mitzvah Video Shoot10:59 AM —
Stylish Westchester preteens steal the show from Marc Jacobs
Death Row Prisoner Sues State for Kosher Food9:18 AM —
Convicted murderer and rapist also seeks $15,000 in punitive damages
Stop Kvetching: Yiddish Isn't Dying8:36 AM —
YIVO director of education says the language is still very much alive
15 American Rabbis You Haven't Heard Of, But ShouldBy Yair Rosenberg — These Jewish leaders' influence has been felt around the country, in every denomination, even if you don't know them by name
Why Great Palestinian Victories Are Worse Than DefeatsBy Edward N. Luttwak — Hamas today is in the same position as Yasser Arafat once was: sacrificing its people to a corrupted ideal
Remembering Tech Titan Danny Lewin, the Fighting Genius on Flight 11By Liel Leibovitz — The first victim of the 9/11 attacks was a veteran of an elite IDF unit, as well as an innovative Internet entrepreneur
Watch Elderly Jews Explain Yiddish Words
Ongoing Controversy Around 'The Most Important Story on Earth'
Study Says All Ashkenazi Jews Are 30th Cousins
How Peace Negotiator Martin Indyk Cashed a Big, Fat $14.8 Million Check From Qatar
Shabbat Is a Day of Rest—But Does That Mean I Can't Text My Friends?
An Insider's Guide to the Most Important Story on Earth
Twitter: tabletmag
- Adam Kirsch reviews @dbezmozgis' brilliant alternate history of an adulterous Sharansky who never was: http://t.co/WsalyC9lzy @jewishbook
Leonard Bernstein: A New Look at His Rise, His Foibles, and His Impact on Music History
The dynamic conductor and genius behind 'West Side Story' also wrote classical works. Allen Shawn explores what they reveal.
How a Reporter Dispelled Myths About Ultra-Orthodox Jews Gaming the System
Batya Ungar-Sargon discusses her exposé on the tax rolls and funding cuts that fueled an ethnic rift in East Ramapo, N.Y.
Elvis Was Our Shabbos Goy
Some people lean on neighbors for a cup of sugar. The Fruchters, of Memphis, Tennessee, needed theirs to help them keep the Sabbath.
- Making Aliyah—With a Little Help From Some Evangelical Christians
- Amy Winehouse Statue Unveiled in London
- Pop Star Harry Styles Lands on List of Britain's Most Influential Jews
- OMGWTFBIBLE Podcast: Holy Cow! A Burning Bush!
- Real Housewives of New Jersey - The Cancer Season
- Janay Rice, Lauren Manzo & Ignorance on Twitter
- ?Manhattan:? The story of the atomic bomb
- Real Housewives of New Jersey is Garbage TV


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Silk emulsion finish to give your walls a wipeable finish with a slight shine. Rich and creamy perfect colour. For use on walls and ceilings. Breatheasy® 99% solvent free.
Paint tin shown is for illustrative purposes only.
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