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Gretchen, thanks a lot! Now I have to get a Carl Sagan bumper sticker.
Gretchen, thanks a lot! Now I have to get a Carl Sagan bumper sticker.
Chrissy, that reminds me of how when I used to work in an office. There was this one girl who was really immature and insanely jealous of me because I got along with everyone and am a fast learner, so people though highly of me and she was always trying to work her way up the ladder but she was not a very good "people person." Anyhow, I realized one day that she had put up a picture in her cubicle of her and me from an office party and had covered my face with a magnet! It stayed that way for weeks. Lol.
I hope you can sort the situation out with your coworker. What a petty thing for him to do.
I've just gotten home from taking Cash to the gp about his eyes. He's started squinting like Travis used to so before getting glasses. The doctor has referred us to the hospital for a proper eye test.
Gretchen, those bumper stickers are great!
I am in love with all of those bumper stickers.
I'm sorry to have been absent the last couple of days. I've been responding to some responses to job inquiries. There's lots to respond to in here and lots of hugs to dispense.
Here's a quick drive-by hug for all my amazing friends, though:
Hope to be able to chat soon!
Yay to job inquiry responses, Myles. I hope you find something perfect!
Good luck to you, Myles!
Claire said something inadvertently hilarious last night.
Claire gave me a hug and said, "You're the best Mommy ever--all the kids say that."
I paused for a moment and said, "Really?"
I said again, "They ALL say that?" I pictured all of her friends at kindergarten and shook my head.
She looked at me and said, "Well, don't all the kids tell their moms that they're the best Mommy ever?"
I swear she didn't do it on purpose.
too funny L!
Oh that is awesome! So clever.
You can tell her that mine tells me that I'm not her best friend anymore every time she is upset with me.
Kate, the picture is precious!! Love it.
Mandy, that is SO true... Good story. I mean, I have an easy, amazing kid, and sometimes I start to think I'm just the world's best mom. And then SHE totally humbles me and brings me back to reality. Sometimes I think about watching another kid, just so she has a friend to play with (like sharing onlies with Gretchen!), but then I think, man, I am SO spoiled, I'm not sure I could handle it! Maybe that's why I can't have a second kid, hah.
Chrissy, say what?? If it wasn't for the fact that you could get in trouble for it, I wouldn't think too much of the cross, but that's just me. But then add in the whole "saving" thing, and UGH. Some people are ridiculous. That's why I LOVE those bumper stickers, haha. You should totally hang a few of those up!
Gretchen, I hadn't thought of that. But you're right. I'm so mad at what fate seems to be telling me, that I know I would have a really, really hard time if those feelings were focused on my husband... Big hugs...
Bridget, thanks for asking! She is doing better today. Still a little sick and a bit cranky, but really, not bad. Her runny nose is gone, and though occassionally she has a minor cough, I think we're good to go. Phew! Yay for shoving nothing but a ton of healthy food in her. I am so lucky I have a kid who will eat just about anything! Even when she wanted junk, I reminded her that she is trying to fight the germs so she will be healthy enough to go camping, and she turned down a cookie!
Well, I am glad you're happy! I understand how he can be so frustrating and you can still love him. Sometimes I feel like all I do on here is whine about my husband, but like with you guys, he is a good guy and I do love him. And I am glad you are so happy with your life!
Keep us updated on the eye test, Ash! Hope everything is good, whether that means glasses or no.
Oh, Myles, so exciting about the jobs. Good luck!!!
L, C cracks me up!
Everyone have a happy Memorial Day weekend!
Ready for an annoying dad update?
I found out, from my mom who heard from my brother (uhh I know), that apparently my dad took off to TN to 'look for a job' because he wrecked his truck (and I am assuming lost the job that he had here, but I don't know for sure). So hubs and I just left it alone. I wasn't chasing him down and dealing with my family in TN, that I don't even like, just to check up on him. Well today, DH gets a call, from my dad saying he needs a ride from a bus station. Seriously?? You take off to TN without saying anything and you call up after 9 o'clock on a Sunday night needing a ride, really??
I am so, so furious right now. He didn't even bother to call me, he called my husband directly because he KNOWS DH is so dang soft-hearted and would drive to go get him. Me on the other hand? I would've told him he better start walking and he knows it.
Between this and my brother calling my phone at almost midnight Friday night, leaving me a drunk message that I could not interpret (oh and is he lucky it didn't wake me up, I called him the next day and told him as much), and than of course my mom and her 'I can't believe your going to cancel my insurance' after I've been paying it for a year, I am just over it. People wonder why I alienate myself from my family?!?!
Please tell me, WHO IS THE ADULT HERE? DH keeps saying 'but they're your parents' and I love him and his big ole heart, but the logic that because you have birth to me, gave me a ****ty childhood, and than landed me with literally no place to go at 18 after DH and I had been paying YOUR way (I don't think I've told ya'll that story, fun stuff) somehow equals that I keep having to 'give give give' for the remainder of my adulthood. No. Forgive me if me and my b*tchy self disagrees.
Anyway, sorry. Crazy hormonal ranting pregnant lady is moving on now....
On the upside, tomorrow is DH and I's 6 year wedding anniversary! Making 9 years that we've been together!
Today started off crappy with me having a hormonal break down and spending a couple hours of me not talking to DH and him not talking to me because every time he did I freaked out. I had every right to be legitimately irritated with him, but I am having a hard time drawing the line between irritated and crazy lady p*ssed off lately. Hormones are fun
We'll be keeping it simple, I don't have the energy to do much here lately. So we're just going to go see a movie and probably go eat or something. Just a few hours hanging out just me and him, so it'll be nice regardless of what we are doing
Christina. Sorry for all the drama.
Me (40) DH (47) & furbabies * m/c 7/08 4/12 11/12
I found out today that my ex is even more disgusting than I thought. After being engaged to someone else after we has been together almost 6 years and lying to me the entire pregnancy and then choosing to be with her and marrying her a week after my due date they have moved back to his hometown. Which is fine. I don't care about that, I'm glad there are hundreds of miles between us. Now his wife is pregnant.
Why do I know this? Good question! People in my life, particularly a friends mother. Stalk him and his wife on fb and text me updates. Even though I have asked for it to stop. This person even went as far as to comment on his wife's page telling her off and going on about what my ex did to me while I was pregnant.
It wasn't enough that he hurt me by walking away from me, and my daughter who he raised with me from a baby and then our sons. I alone dealt with the death of Nathaniel and everything that came with it. I was alone every day for the 5 weeks that Parker was in the nicu. I'm alone everyday taking care of the kids. After just over a year they are married and having a baby and after 6 years I'm alone, caring for two kids and grieving for another. I have never been so hurt in my life. I hate them both so much. I hate anyone who tells me what they are doing. I just want to forget about them. And now I want to forget she is pregnant.
Christina, I wish I had some wise words for you regarding the family. I know that your own little family unit is a strong one, so you'll be ok no matter what happens with the rest of them. My own extended family is full of drama, so it's nice to live so far away some times.
I do miss my parents, though. They keep out of the drama most of the time. I wish I could fly back there this week. My dad's best friend died of a heart attack a few days ago. He was a very close family friend. He had been poorly for about a year and only just recently retired at 77 years old. I will send a sympathy card but wish I could do more.
Rachael, gosh that must sting that he just moved on just like that. You are a strong woman to have come through all that you have. Keep your head up. Your beautiful children will look up to you for being so strong. As for the person constantly updating you on the ex, I think I would have to tell them to stop or all contact would have to be stopped as it's causing you too much sorrow to keep hearing what he's doing.
Racheal, I will admit that I didn't know the details of your story, only that you were going it alone. I am so sorry you have been through to so much and you must be incredibly strong to keep on truckin on. Your kids are so lucky to have you. I agree with Ash that whomever is giving you these updates needs a firm ultimatum. Don't they know how toxic it is for you to have to think about his life? Not healthy for you as you recover from the damage he had done to you. I'm so sorry.
Oh no, R, you can block that person who is texting you the updates if she won't listen to you. You don't need any pot-stirrers around to stop you from finding some peace in your life. That news must hurt so much. I'm so sorry.
Christina, I hope you had a good anniversary, and I'm sorry you are dealing with misbehaving parents (so much worse than misbehaving kids, because they're adults and somehow you'd think they should know better). Ash said it very well. It is great that you have developed a stable family unit that is your own place of security and love and that your own children will be able to grow up in.
We saw that the weather was going to be on the nice side today (read that as not raining!), so we planned on going over to the Yorkshire Dales to an American Diner that does great burgers and ice cream. It was a bit cool here but the sun was shining. We got in the car and drove the hour-long drive to the place only to be told that there was a 2.5 hour wait for food and the weather was overcast and cold! The kids were fine because I packed them hoodies, but I hadn't brought a coat and Rich had shorts on! We ended up driving the scenic route home and found a proper old country pub and had some dinner there.
When we got home, the boys did a lot of bickering and fighting, which really seemed to wear Rich down, so he shouted at them and sent them to bed early. I felt it was too harsh a punishment and told him so afterwards. He apologised and said he'd make it up to the boys tomorrow, but it has left me in a bad mood. He went out to play 5-a-side soccer with the other dads from Trav's school and I'm glad he's out of the house for a bit. He made a sarcastic remark to me about hanging a towel on the heated towel rail in the bathroom instead of hanging it on a door as well and I told him that if the kids weren't around at that time I would have told him to bugger off but in not so nice a way.
I think I'll go find something to eat because my blood sugar must be low with me feeling this bah-humbuggish!
Not cool. Sorry you had a rough patch with the dh Ash. It seems unusual for you two.
My weekend with John was great. We went out to see a friend's band and surprised my former (John's current) coworkers. We knew one would be there, but another also happened to stop in. It was wonderful to see those two. I miss them dearly. I'm not sure if they 'know' what's going on because we didn't make it this big thing, but I'm also thinking seeing the two of us out and about at a bar where he's buying my drinks all night tells the story.
I met his brother who greeted me with a big hug & kiss. I adore him already. We spent most the weekend chilling around the house (only today was nice enough to sit outside, unfortunately) and talked our heads off. Both deep stuff and inconsequential funny stuff. He made me laugh so hard I nearly peed my pant. It's something I'm prone to do, but I really have to laugh hard. It's been years since I've had that close of a call.
Last night I was laying in bed and he sat at the foot of it playing his guitar. I knew he played, but it was the first time I've heard him. I laid there thinking if it were possible, I think I love him more.
He really spoiled me. I was lazy-he cooked and cleaned and bought everything. We drove me around a bit and showed off his little town, and we stopped for lunch in Watkins Glen (where the nascar races are held-he lives in that vicinity). I left knowing we're most definitely on 'the same page' and I love him an awful lot. Outside of my kids, he's easily one of the most important people to me in my life. And I did tell him so.
Yeah, we rarely bicker at all, so when it happens it sometimes feels like we (well, more like I) blow it out of proportion. As a result of sending them to bed early, Cash was up just before 6 am. Yawn.
Chrissy, your weekend sounds lovely! I'm so happy to hear such a positive news from you. I smiled at the guitar-playing part. I love when Rich picks at his guitar. There's something intimate when there's just 2 of you and a strumming of guitar.
Happy Anniversary Christina!
Chrissy that sounds like a great weekend. I wish my DH played guitar...we have one and he made up a song on it for me once but he doesn't really know how to play it and it's really out of tune now.
Ok so I have the dog question of the day....do dogs get leg cramps? Cosmo did this twice recently...Thursday and Saturday nights where she was stretching....she is normally a champion stretcher....and started holding her front leg up funny and cried a bit. I ran over and picked her up and massaged her and kissed her head and a few minutes later she could walk but limped a bit. Another hour later and she was fine. It seems to be more up near her shoulder and not the foot. She is not a drama queen like Molly so I know that if she whined about it hurting, that it hurt her. I'm thinking maybe a cramp or a locking of a joint? It is the same arm where she has a decent sized fatty lipoma on the arm right at the pit area.
I noticed this morning that it looked like she was being a little more careful in her stretching of that leg.
Of course we are going to be taking her to the vet to talk about this and see if we should get this lipoma removed. I do think it bugs her sometimes but not sure if the removal is worse than just letting it be? Sometimes when sitting she will adjust that leg a few times lifting it up and down and it's like she's getting the lipoma into a better position.
She is due for a dental cleaning so we will be doing bloodwork and she will be under anesthesia anyway. And she is due for shots and they want to do a yearly eye exam before renewing her eye drops.
Cosmo will be 10 this year but for a dog her size, it's not unreasonable to think she could have another 5 years left.
Happy Anniversary, Christina!
Jennifer, dogs can get strains and sprains and have temporary issues like that for sure. As long as she is having bloodwork done, you may well do a lyme test/tick panel, and get her joints x-rayed. She might be developing a touch of arthritis, for instance.
I read everything else, but can't remember any of it for now. Except for remembering that I wanted to comment on other stuff. Growing old sucks, I tell ya.
Oh I didn't think of an x-ray. I always think of arthritis in dogs in the back legs and hips. I know she is more stiff than she used to be. A while ago...maybe over the fall or winter I don't remember when, she did hurt her leg jumping on the bed but I cannot recall if it was this one or not. I am leaning strongly towards it was the same leg.
Don't think it would be lyme...she's gotten the lyme vac yearly since we move to the northwoods area because it is so common here. She did have a tick attached to her head in Nov. but I don't think it was attached long enough to transmit disease and she's not had the symptoms for ehrlichiosis (one of the other tick diseases common in my area).
I do worry about her joints though because she's been overweight for the past 2-3 years. Started after she was put on seizure meds and in a year pretty much went from 22-33 lbs. And that was with us trying to get her to exercise and keeping her food very controlled. In December we realized her thyroid was off and she got on thyroid meds. She has lost some weight but not sure how much....but everyone can see it. Only bad part is she has a lot more energy now and I think once in a while forgets she is almost 10 and not 5.
Hope you all had a decent holiday yesterday. We finally planted the grass after DH put off sod cutting on Friday evening and so we did everything - cut sod, rolled up sod (a whole butt load of work I tell you!), fertilized dirt, tilled dirt (luckily a friend came by who wanted to "show us how to do it right" and so we let him) planted grass, put hay down, and figured how to set automatic sprinkler system - on Saturday so I am beat!!! Now I only have to re-do my flower beds and make a new one, I enlarged one so that we wouldn't have to plant as much grass. DH has been pretty chill since I was about to punch him in the face. He also started some counseling and has been better over the last two months, hasn't said anything demeaning or disrespectful IMO to Ky. He knows I will punch him in the face if he does, and sorry if it offends, but I really will because I feel when he said the things he was saying it was like him punching Ky in the stomach so now he knows he will face similar feelings if it comes to that again. Sorry, would hit "enter" here but the breakroom computer here at work has a jacked up keyboard and neither one off the "enter" keys work for some reason. But speaking of Ky, he graduated from 5th grade last week. I cannot believe he is a middle schooler now! He is now 5'3" and 115lbs so is pretty big for an 11 year old. I have been speaking to him about staying motivated to do tasks, especially school work or chores he doesn't want to do and asked him what would be a big motivating factor for him and it was too funny to me that he piped up immediately "FOOD!" So now I am afraid of the soon to be teenage boy appetite invading my house.
Ahhhh! Ky is the same size as me! Crazy. I am glad to hear that dh has been better. I have been wondering how you guys are doing.
Chrissy, what a nice weekend!
Erin, so glad things have been going well for you and your dh. Congrats on having a middle schooler! That lawn sounds like a ton of work! We have been doing the same but in smaller increments - tilled one weekend, trenched one weekend, took us a couple of weeks to get the sprinklers in. This weekend we laid sod. Dh's back and arms have been out of whack lately so he rolled out and placed the sod while I carted it in -- 5 rolls of sod at a time, 40 lbs each, that I threw on the handtruck, carted to the backyard (Noe riding on top), and put out on the dirt in the right spots. 50 rolls in all -- hard work, but I was pretty pleased that my fitness level was up to it. I wasn't even sore the next day. Our next door neighbor made a little joke about how it was funny that my dh, who is 6'4"/220, was rolling out the sod while I, a foot shorter and 100 lbs lighter, hauled it all. But after having a sort of frustrating relationship with my health over the past year, it feels great to me to be able to do hard physical labor.
My parents came into town too over the weekend and we ran around looking at houses and boats. They are looking to buy in a 55+ community when my dad retires next year ... they've been looking all over the country, but now they're excited about a place an hour away from us, which makes me happy because I was concerned about them growing older in a place where I wouldn't be able to help care for them if they needed it. I hope it works out for them.
All that yard work!! My goodness, it sounds like hell to me. I'm sure your lawns look lovely, while mine...meh, I have no delusions I'll ever have anyone covet my yard.
Erin, I'm so glad dh is being kinder to Ky in his speech. I don't think some people (especially men) realize how some things can just 'stick' and cause psychological harm.


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The suspect who fled the scene of a traffic stop in Upshur County Saturday night was apprehended Sunday in Gregg County.
Lieutenant Fitzgerlad with the Upshur County Sheriff's Office tells KLTV that the suspect was apprehended Sunday, but that no other details were yet available.
Saturday evening, the suspect was being pulled over near the intersection of U.S. Highway 271 and North Point Pleasant Road, then fled the scene running southeast into nearby woods.
Authorities called off the search late Saturday night after they determined that the suspect was not a threat.
We are continuing to work to get more information on this story and will have the latest posted on KLTV.com
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Advances in Imaging Reveal New and Better Ways to Fight Cancer
Imaging may be the most rapidly advancing technology in oncology today. Far beyond the traditional uses to screen, stage disease, and follow patients for recurrence or progression, we now have the ability to image across various levels of biological organization, not just organs or tumors, but also molecules, single cells, and tissues. Such information - obtained in real time and noninvasively - can provide important details about whether patients may be candidates for certain therapies or provide a rapid assessment of whether they are responding to treatment.
This special issue of the NCI Cancer Bulletin provides a window into just some of the exciting work being done in the field of cancer imaging, from individual research projects to NCI's support of companies developing new imaging technologies through our Small Business Innovation Research Program or through collaborations with private-sector partners as part of NCI's recently launched Advanced Technology Partnerships Initiative. Read more
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When NCI's new Molecular Imaging Clinic opens in January 2009, it will be one of the few places in the world where state-of-the-art imaging tools are dedicated to understanding how drugs behave in people with cancer. What is learned there could help investigators determine how best to use existing drugs and determine the properties of new molecularly targeted drugs that are just entering the clinic.
"Our goal is to use advanced imaging technologies to accelerate the development of therapies for cancer," said Dr. Peter Choyke, who directs the Molecular Imaging Program in NCI's Center for Cancer Research (CCR). He has assembled a multidisciplinary team that includes imaging scientists, chemists, physicists, engineers, oncologists, and molecular biologists. They have many collaborators inside and outside NCI. Read more
Advances in Imaging Reveal New and Better Ways to Fight Cancer
Imaging may be the most rapidly advancing technology in oncology today. Far beyond the traditional uses to screen, stage disease, and follow patients for recurrence or progression, we now have the ability to image across various levels of biological organization, not just organs or tumors, but also molecules, single cells, and tissues. Such information - obtained in real time and noninvasively - can provide important details about whether patients may be candidates for certain therapies or provide a rapid assessment of whether they are responding to treatment.
This special issue of the NCI Cancer Bulletin provides a window into just some of the exciting work being done in the field of cancer imaging, from individual research projects to NCI's support of companies developing new imaging technologies through our Small Business Innovation Research Program or through collaborations with private-sector partners as part of NCI's recently launched Advanced Technology Partnerships Initiative.
The extent of the activity in this field is truly remarkable and too broad for us to do it justice in 8 pages. Researchers from the Siteman Cancer Center in St. Louis, part of the NCI Alliance for Nanotechnology in Cancer, for instance, are using nanoparticles as part of an MRI scan to construct three-dimensional maps of tumor-induced angiogenesis and monitor the effects of drug therapies on those new blood vessels. Other researchers are modifying targeted therapies so that they can be used as imaging agents.
Imaging advances may be able to vastly improve standard treatments like surgery. For instance, a team in NCI's Center for Cancer Research (CCR), led by Dr. Hisataka Kobayashi, has developed a fluorescently tagged cancer-specific antibody that can put a spotlight on micrometastases. Although still at the preclinical stage, this work has the potential to allow cancer surgeons to eradicate insidious tumor "seedlings" well before they have the chance to threaten a patient's life.
Advances in imaging technology are also providing investigators with the means to explore entirely new realms of molecular biology. In CCR, Dr. Tom Misteli is using live-cell imaging and high-resolution microscopy to map the position of chromosomes within a cell's nucleus, something Dr. Misteli and his team have found can influence how cells function during processes like early tumorigenesis. Their work may eventually point to new possibilities for early detection.
My belief is that every clinical trial should have an imaging component to help answer important research questions. Along those lines, NCI's new Molecular Imaging Clinic at the NIH Clinical Center will play a pivotal role in allowing researchers to quickly assess whether a drug is likely to have its intended biological effects. Such information will speed the development of new drugs into more advanced trials, saving both time and valuable resources.
I hope you find this special issue informative. It underscores the fact that translating this research into the everyday care of patients and the conduct of clinical trials is a high priority for NCI. The progress to date has been remarkable, and I'm confident that its impact on the cancer burden will be substantial.
Dr. John E. Niederhuber
When NCI's new Molecular Imaging Clinic opens in January 2009, it will be one of the few places in the world where state-of-the-art imaging tools are dedicated to understanding how drugs behave in people with cancer. What is learned there could help investigators determine how best to use existing drugs and determine the properties of new molecularly targeted drugs that are just entering the clinic.
"Our goal is to use advanced imaging technologies to accelerate the development of therapies for cancer," said Dr. Peter Choyke, who directs the Molecular Imaging Program in NCI's Center for Cancer Research (CCR). He has assembled a multidisciplinary team that includes imaging scientists, chemists, physicists, engineers, oncologists, and molecular biologists. They have many collaborators inside and outside NCI.
The clinic was created in part because the existing imaging tools in the NIH Clinical Center were needed for patient studies, leaving little time for translational research. As molecularly targeted therapies were emerging several years ago, NCI officials saw the potential importance of imaging studies in drug development.
"Imaging can answer three important questions," said Dr. Choyke. "Does a patient have the target of a particular drug? Does the drug hit the target? And if so, does it do anything helpful for the patient?" When imaging shows that a drug has not reached its destination, researchers can modify the drug or its delivery. Or, they can abandon the project and redirect precious resources elsewhere.
The new facility has undergone extensive renovation and will have the latest scanners for detecting cancer and tracking drugs in the body, including a PET/CT unit, which can simultaneously capture PET and CT images, and 3 Tesla whole-body MRI.
Imaging studies are underway to study the behavior of drugs such as trastuzumab (Herceptin). Experimental imaging agents also will be tested in phase 0 trials - small studies in which patients receive a very low dose of an experimental drug to determine whether it behaves in people as it does in animal or cell models.
Many studies will be partnerships with investigators at NCI, other institutions, pharmaceutical companies, and the imaging-equipment industry. NCI's Division of Cancer Treatment and Diagnosis played an integral role in the clinic's development and provides critical materials such as radioactive substances that are attached to drugs.
Radiolabeled drugs are given at low doses so they do not result in physiologic effects, but they still go to the same places in the body as drugs given at therapeutic doses. Investigators may eventually make "go" or "no-go" decisions about new drugs based in part on whether they hit their target and whether they have off-target (side) effects.
"Our mission is to use the cameras to do translational studies that will make drug development faster," said Dr. Karen Kurdziel, who directs the new clinic. "There are very few imaging centers dedicated to drug discovery and research. We have an incredible opportunity here."
Dr. Sriram Subramaniam and his team in CCR's Laboratory of Cell Biology develop tools and strategies for capturing images of cells and viruses, with a focus on HIV and cancer. His group recently won an award for the image of a melanoma cell (below) and published three-dimensional (3D) images of the structures HIV uses to enter cells, created with a technique called electron tomography.
What is your mission?
What are your interests?
Have your melanoma studies revealed surprises?
How is this information relevant to patients?
"Imaging technology is used across the entire spectrum, from very basic research to clinical care," says Dr. James Tatum, associate director of NCI's Cancer Imaging Program (CIP), which is part of the Division of Cancer Treatment and Diagnosis and currently funds a portfolio of over 400 grant projects.
Part of CIP's mandate has been to support areas of cancer-imaging research considered too high-risk for commercial investment. Through its Imaging Development Group, it helps shepherd promising new imaging compounds from discovery through early clinical testing. Several of these new agents are now in clinical trials across the country, with more in the pipeline.
To speed up and improve early clinical trials of these and other promising new imaging agents, CIP has been working closely with the American College of Radiology Imaging Network (ACRIN), an NCI-funded cooperative group.
Best known for performing large trials of mature imaging technology, such as the National CT Colonography Trial, ACRIN has received assistance from CIP to conduct early multicenter trials as well, explains Dr. David Mankoff, professor of radiology at the University of Washington and an ACRIN investigator. Examples of agents being tested in these smaller trials, coordinated through ACRIN's Experimental Imaging Sciences Committee, include 64Cu-ATSM to measure treatment response in cervical cancer, and 18F-fluoromisonidazole to monitor brain-tumor hypoxia (decreased oxygen supply).
A huge challenge in trials of these and other imaging radioisotopes is that "many of these probes have extremely short half lives, about two hours or so," explained Dr. Mankoff. "You can't just make them in one place and ship them all over the country - you have to have a distribution network." Fortunately, the clinical success of FDG-PET imaging has led to a commercial distribution network to make and distribute the fragile FDG isotope to clinical sites across the country. CIP "has been key" in convincing members of this network to also manufacture experimental probes for ACRIN, said Dr. Mankoff.
CIP also helps fund advanced imaging research laboratories around the country, including one that has the first dual MRI-PET device in the country, commissioned by Dr. Gregory Sorensen and colleagues at Massachusetts General Hospital.
"We are now able to combine the high spatial resolution and functional information from MRI with the metabolic and receptor information available from PET, to more carefully study tumor hypoxia, angiogenesis, and the link between [tumor] metabolism and response to therapies," explained Dr. Sorensen, who will soon begin the first clinical trial (funded in part by CIP) of dual MRI-PET to monitor patients with brain tumors during treatment.
Imaging technology is also poised to help researchers visualize the intricate inner workings of cancer cells. To this end, CIP has funded eight In vivo Cancer Molecular Imaging Centers that will help advance cellular and molecular imaging related to cancer.
"There is a compelling need to understand cancer from a systems biology perspective, and tumor biology is the most complex system you could possibly imagine," says Dr. Tatum. "It is my own belief that the only way you can understand what goes on in these complex systems in vivo is to be able to monitor or interrogate the system non-invasively employing advanced imaging methods across the resolution from cells to patients."
After experiments show that a new imaging technology can work, it's also important to confirm that its use in practice lives up to its promise. This effort is underway through the Division of Cancer Control and Population Sciences' Applied Research Program (ARP).
"We use physician surveys to understand attitudes about new technologies, but we also need to collect data in the course of delivering care to understand whether the new test is performing as it did in the efficacy studies…studies that are, after all, performed with staffing and coordination that may not be present in practice," Dr. Stephen Taplin, senior scientist in ARP, explains.
Dr. Taplin oversees the Breast Cancer Surveillance Consortium, a research network focused on understanding how current breast cancer screening methods operate in practice - how breast density, for example, affects cancer detection and whether new training software can improve radiologists' performance and make mammogram interpretation more accurate.
Mammography is a mature technology, notes Dr. Taplin. "We've had decades to evaluate its strengths and the consequences of its deficiencies." But as new technologies debut at a faster pace, the time to anticipate challenges and ask questions - and the resources available to address them - shrink. One solution for mammography evaluation was a resource-sharing partnership between federal and nonprofit agencies like the American Cancer Society.
Dr. Carrie Klabunde, an epidemiologist in ARP's Health Services and Economics Branch, manages a portfolio of research projects aimed at understanding the uptake of colorectal cancer screening in community practice. She is leading an effort to begin monitoring the use of virtual colonoscopy in the United States.
Virtual colonoscopy is a new technology to screen for colorectal cancer that uses external imaging devices to examine the lining of the colon. "There is still a need for high-quality data on ways of efficiently delivering virtual colonoscopy in practice, and on the procedure's outcomes," she notes.
One issue, for example, is suspicious findings that are inadvertently detected outside of the colon. "These findings could be anything from a tumor on a kidney to something that's completely benign, a lump of fat or normal variation on an organ," explained Dr. Klabunde. "There will be questions about who is responsible for finding out what that lump or bump may be, and who will pay for it. That will be one challenge ahead."
"There is a tremendous need for objective parties to look at issues such as these, because there are so many competing interests involved and because the analysis requires scientific rigor," said Dr. Taplin. "It's important for us to fund investigators who can look carefully and make sure that the technology is achieving the ends that we expect."
To build national capacity for monitoring the performance of colorectal cancer screening modalities, Dr. Klabunde and collaborators at the Agency for Healthcare Research and Quality have sponsored studies to develop and evaluate data systems for tracking colorectal cancer screening performance. A recent supplement to the journal Medical Care describes this research and can be ordered at http://healthservices.cancer.gov/publications/improv_deliv.html.
When used in appropriate situations and with careful attention to dosage, leading experts agree that the potential benefit of cancer imaging outweighs the risk. However, there has been mounting concern that several increasingly common imaging modalities may expose patients and health care workers to potentially unsafe radiation doses, the consequences of which only become evident with long-term population-based research.
Computed tomography (CT) has come under intense scrutiny because the number of procedures has skyrocketed to more than 60 million annually, a nearly threefold increase since the early 1990s, and the average number of scans per patient is also increasing. The wider use of CT can be traced in large part to its speed and its remarkably clear images of organs and tissues. But the downside, explains Dr. Elaine Ron, a senior investigator in NCI's Division of Cancer Epidemiology and Genetics (DCEG), is that CT requires significantly greater doses of radiation compared to a conventional x-ray. In the case of abdominal CT, for example, the dose is 50 times higher.
Among the chief concerns is use of CT in children. With their still-developing bodies, experts warn, they are more prone to radiation-induced effects that can increase cancer risk. Such concerns led NCI to partner with the Society for Pediatric Radiology to develop a brochure, recently updated, to help educate health care workers about appropriate CT use in children and the potential risks of CT-emitted ionizing radiation. DCEG researchers are also collaborating with researchers from Newcastle University in the United Kingdom and Maccabi Healthcare Services in Israel to investigate the risk of cancer in children and adolescents who have undergone CT scans.
CT is not the only radiologic procedure that NCI researchers are studying. Other diagnostic techniques and treatments that rely on a type of x-ray technology called fluoroscopy, especially coronary angiograms and angioplasty, are proliferating. Because of the length of these procedures, the cumulative exposure to radiation is considerable. In conjunction with five medical societies, NCI has launched a study to determine whether radiologists and cardiologists, among others, who are involved in fluoroscopy-guided procedures have a higher risk of cancer.
The research began because of reports of certain cancers that appear to arise more often among physicians who perform fluoroscopy, explained Dr. Amy Berrington de Gonzalez, an investigator in DCEG's Radiation Epidemiology Branch. There have been efforts by NCI and other medical societies to educate medical personnel about the potential radiation-related risks associated with these procedures. However, the available evidence, including some surveys conducted by the FDA, suggests the message still isn't getting through, particularly to those without extensive radiology training, she stressed.
The long-term study will compare cancer-related deaths between physicians regularly involved in radiation-related procedures and those who are not involved in such procedures. "Then we'll be able to determine whether increasing use of these new imaging technologies are associated with an elevated cancer risk," she says.
NCI recently completed the retooling of its Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs to enhance their role as an engine of innovation, and cancer imaging technology is one of the top priorities for the programs.
In 2007 at the request of former NIH Director Dr. Elias Zerhouni, NCI took the leadership role in developing new initiatives for the small business set-aside research programs across all NIH institutes. One of the major changes was to consolidate the management of NCI's more than 300 small business projects - previously scattered across the Institute's numerous research divisions - into a new NCI SBIR Development Center, staffed by professionals with specific industry and entrepreneurial expertise. Cancer imaging technologies are the largest single component of NCI's small business portfolio, making up about 30 percent of all such projects.
Dr. David Beylin was recently hired for NCI's small business center. He came to NCI from Naviscan, Inc., a medical device company which used SBIR funds to take its PEM Flex PET Scanner - a device that combines PET technology with mammography, revealing with high accuracy and sensitivity breast tumors as small as a grain of rice - through the stages of development, prototype building, and clinical trials. The SBIR funds enabled Naviscan to raise more than $20 million of venture capital, obtain FDA clearances, and start selling the device in the United States.
To avoid the "valley of death" that many former SBIR projects encounter after the NCI funding for their projects ends and before private investors are willing to pledge support, another new NCI initiative offers small businesses the opportunity to compete for SBIR Bridge Awards to extend funding up to a total of $3 million over an additional 3 years.
Cancer imaging and therapeutics are the two priority areas for the Bridge Awards, noted NCI SBIR Development Center Director Michael Weingarten. Recently for the first time, the SBIR peer-review panels for the Bridge Awards included panelists with venture capital and entrepreneurial backgrounds. The reviewers' discussions "broke important new ground by evaluating both the science and the commercialization strategies of the companies' proposals," he noted. "The salient feature of this award is that it encourages partnerships between NIH's SBIR Phase II awardees and third-party investors or strategic partners that have significant prior experience in the commercialization of emerging technologies."
In diffuse large B-cell lymphoma (DLBCL), researchers have identified three patterns of gene activity in and around tumors that may determine survival following therapy. These patterns, or gene signatures, were associated with survival in three independent populations of patients treated with standard therapies for the disease.
The results suggest that DLBCL, like other cancers, is not a single disease but rather consists of multiple, biologically distinct subtypes. In addition, the study highlights the importance of the tumor microenvironment - the nonmalignant host cells adjacent to tumors - in some forms of the disease.
Dr. Louis M. Staudt of NCI's Center for Cancer Research (CCR) and his colleagues in the Lymphoma/Leukemia Molecular Profiling Project published their findings in the November 27 New England Journal of Medicine.
"Interestingly, we found that it's not just the characteristics of the malignant cells that influence patient survival, but also features of the tumor microenvironment in the lymph node," said Dr. Georg Lenz of CCR, the study's first author.
The team analyzed 414 pretreatment biopsy specimens from two groups of patients and linked the results to clinical outcomes. This revealed a previously unknown gene signature and confirmed two signatures identified in an earlier study. One of these signatures, called germinal-center B-cell, is based on gene activity in malignant lymphoma cells; it distinguishes two forms of the disease, known as germinal-center B-cell-like and activated B-cell-like DLBCL.
All three signatures were validated in a third patient population; each was also found to predict survival after treatment with combination chemotherapy called CHOP or CHOP plus rituximab (Rituxan).
The researchers suggest that their results have implications for clinical trials. Some patients have a better prognosis regardless of the therapy, and this could make a drug seem better than it actually is. "When you are enrolling patients on clinical trials, you need to know which kind of DLBCL is being treated so that the results can be assessed accurately and compared across trials," said Dr. Staudt.
For instance, patients with a tumor-microenvironment signature called stromal 1 tended to respond to treatment. But those with a microenvironment signature called stromal 2 had an inferior prognosis.
The stromal 2 signature includes genes linked to angiogenesis, the growth of tumor blood vessels. Based on this finding, the researchers propose that these patients may benefit from antiangiogenic drugs, such as bevacizumab (Avastin), while other patients may see little benefit from these agents.
"One wonders whether an antiangiogenic agent should be added to the treatment of patients with a lymphoma containing the stromal 2 signature," writes Dr. Charis Eng of the Genomic Medicine Institute at the Cleveland Clinic in an accompanying editorial.
Dr. Eng praised the study, noting that the results are consistent with recent studies showing a connection between the tumor microenvironment and clinical outcomes in other cancers.
"These findings give us a completely new way of thinking about this lymphoma," said Dr. Staudt. Researchers may now shift some attention away from malignant cells and toward developing a better understanding of tumor microenvironment, he added.
After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use
Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute.
Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the U.S. population, 58 percent of the women in the study were overweight or obese. The women were not using postmenopausal hormone therapy when they received their mammograms between 1996 and 2005; 4,446 of them were diagnosed with breast cancer within a year of getting a mammogram.
Compared to women with a normal body mass index (BMI 18.5-24.9), risk for the first year after a mammogram was about 12 percent higher in overweight women (BMI between 25-29.9), 20 percent higher with a BMI between 30-34.9, and 30 percent higher when their BMI was higher still. Similar but independent patterns were found for high-grade, advanced-stage, estrogen receptor-positive, and large invasive disease. Factoring in the frequency of the women's previous mammogram use did not change these results.
Though under-using mammography did not entirely account for the higher rate, the authors cite its value as "the only secondary prevention measure that has been proven to decrease breast cancer mortality" by detecting disease at an earlier, more treatable stage. And though the link found here between higher BMI and advanced stage disease was moderate, it was also conclusive. "Our results suggest that postmenopausal women who are overweight or obese…should be encouraged to lose weight and to undergo routine screening mammography, two factors that may decrease the number of women who are diagnosed with advanced disease," the authors wrote.
Breast Cancer Family History Boosts Risk, Even without BRCA Mutations
Women who test positive for gene mutations associated with breast cancer often take steps to prevent the disease. But little is known about what steps, if any, women should take if they have a family history of breast cancer but lack BRCA1 or BRCA2 gene mutations. Now, a new study suggests that the risk among these women may be high enough that they should discuss prevention options with their physicians, such as screening with breast MRI and chemoprevention with tamoxifen or raloxifene, according to the study's author.
Women with a significant family history of breast cancer have an approximately fourfold increased risk of developing breast cancer compared with the general population, even if they do not carry the high-risk mutations, the study found. A significant family history is defined as two or more close relatives with the disease under age 50, or three close relatives with the disease at any age.
Dr. Steven Narod of the University of Toronto presented the findings last month at the Frontiers in Cancer Prevention Research conference near Washington, D.C. He urged physicians to discuss prevention with the thousands of women who test negative but have a significant family history of breast cancer. "We've been doing this testing since 1995, and there is a huge population of women out there whose risk is very high. And yet they have not been targeted for prevention," he said at a press briefing.
"We don't need to wait for the future," Dr. Narod added. "We should be able to implement this now."
His team followed 1,492 women who tested negative for BRCA1 and BRCA2 mutations from 365 families for at least 5 years. Based on the number of breast cancers in the group versus the number expected in the general population, the researchers calculated that a significant family history was associated with a 30 to 40 percent lifetime risk. By comparison, carriers of BRCA mutations have a lifetime risk of the disease as high as 85 percent.


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- Archaeology, Ancient History and Classics
- Bioethics
- History
- Human Rights
- Institute for Public History
- International Studies
- Jewish Civilisation
- Philosophy
- Religious Studies
- Archaeology, Ancient History and ClassicsArchaeology, Ancient History and Classics aims to furnish students with the investigative, analytic and interpretational methods and techniques appropriate to their area of study... Read more
- BioethicsThe Centre for Human Bioethics was established by Professor Peter Singer in 1980 as Australia's first research center devoted to bioethics, and it has developed into one of the world's leading Centres of its kind... Read more
- HistoryHistory is not simply about dates and facts. Rather it is about new ways to interpret and make sense of the past... Read more
- Human RightsIn the era of globalisation, one of the most important concepts in international affairs is the idea of a human right... Read more
- Institute for Public HistoryThe Institute for Public History aims to raise community awareness of the importance of history and heritage by promoting events and publications (both online/print) that foster public knowledge of history... Read more
- International StudiesThe International Studies Program gives students the opportunity to explore the past, present and future contours of the globalised world in which we live in today... Read more
- Jewish CivilisationThe Australian Centre for Jewish Civilisation teaches and researches Jewish studies, the Holocaust and genocide, Israel and the Middle East... Read more
- PhilosophyMathematicians, economists, students of medicine, students of politics, students of physics, theologians, linguists, critics of literature and the arts – all these and more will encounter philosophical problems... Read more
- Religious StudiesThe Centre for Religious Studies was established by the Faculty of Arts... Read more
The School of Philosophical, Historical and International Studies' teaching covers many of the key areas of human societies and includes programs at all levels: research degrees, postgraduate coursework, and majors within the Bachelor of Arts and the Bachelor of Letters. It forms an active research community, producing many publications for both scholarly and general audiences.
Areas of Study and Research
Latest News
- The Australian Generations Oral History Project has interviewed 300 people living in Australia born between 1920 – 1989. The interviews explore Australian life and society across time, and illuminate generational change and inter-generational dynamics. This event is the researchers' first opportunity to share their findings about 20th and 21st century history and memory. Read ... Read more
More News
- "Controversial Questions about Life" Julia Hinde 25 October 2013 The Age click here to read article Read More... Read more
- SOPHIS has made new appointments in the following areas: The Centre for Studies in Religion and Theology has appointed Dr Scott Dunbar to a three year Lectureship beginning in July 2013. Dunbar is currently an Assistant Professor of Global Issues at the UPEI, Canada. He possesses a completed interdisciplinary doctorate in religion and social issues ("Classical ... Read more
- Congratulations to SOPHIS staff: 2013 Dean's Award for Excellence in Research by an Early Career ResearcherThe 2013 Dean's Award for Excellence in Resarch by an Early Career Researcher was announced last week – congratulations to Dr Catherine Mills of the philosophy program for winning the award, and congratulations also to Dr Adam Clulow of the history program who has been highly commended. Dr Mills graduated with a PhD in the discipline ... Read more
- Monash History and Philosophy were ranked highly in the 2011/12 QS World University Subject Rankings Monash History ranked 4th in Australia, 21st in the world Monash Philosophy ranked 2nd in Australia, 26th in the world. Published annually since 2004, QS World University Rankings provide an important indicator of academic excellence. For more about the ratings see: QS World University Rankings by ... Read more
- The University of Warwick (UK) and Monash University (Australia) have signed a new agreement to create an alliance between the two universities that will clearly establish both as "globally networked universities". SOPHIS is currently working with Warwick on three important projects A team led by Adam Clulow and David Garrioch is working with staff at Warwick's Global ... Read more
- Studying Religion and Theology at Monash The Centre for Religious Studies is devoted to the critical study of a wide range of religious traditions, as interpreted both in the past and in the contemporary world. It is also concerned with thinking about the ways in which specific religious traditions (such as Buddhism, Judaism and Christianity) engage ... Read more


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Pacsafe Slingsafe 250 GII Handbag 8 8
Great LITTLE Bag I bought this little bag over a month ago in Cypress Green. I love a small bag at times and thought this would fit the bill. It's wonderful. The only problem I have with it is what they call the "origami styling." Unfortunately, those lopped off corners in a bag this small make the usable space really tiny. I can get a very small wallet, car key, lip gloss and a couple of tissues inside the main compartment. My phone goes in the outside zipper compartment. And that's it. No sunglasses or anything else will fit. However, that's enough for me at times (although I would like my glasses with me) and because I can put it across my body very comfortably it's so convenient. My hands are free to do other things and my pockets are not stuffed and bulging. I can't get a passport in it which is unfortunate because this would be so wonderful for travel if it was just that much bigger. The green is a wonderfully neutral color without being the same boring black and brown I normally carry. I have about ten PacSafe bags and this one is a favorite. February 24, 2012
Great Travel Purse I bought this bag in light green last yr.for a 3-month trip to Australia. It performed well. Very comfortable cross body bag leaving hands free if you like. Liked the RFID feature for credit cards. It was roomy enough for all of my essentials including cell phone. Liked everything about it except the light green showed the soil on the body of the bag in oval areas where the wiring ran on the inside of the bag. I did wash the bag, but not all came out. I used it again this winter for our 3-month trip and it got even dirtier. Just ordered the same bag in black for future trips, which I am hoping will solve the problem of the oval wire dirt marks. I wouldn't have ordered a second bag if I hadn't liked it so much. The light color just showed the soiling too much. April 22, 2014
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Very handy little bag Bought this bag to use on a resort/beach vacation near Playa del Carmen. Despite it's small size, it holds quite a bit and I felt my valuables, credit cards and money were secure when I carried it into town. Very lightweight while holding all you need. Love it. April 24, 2013
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Love this bag!!!! I waited a few months before reviewing this purchase and I have been very pleased with one exception which will be explained later. If I could give four and a half stars, I would. This carries quite a lot which follows: inside pockets: cell phone, my palm pilot, lipsticks, pens, lip gloss, extra cell phone battery and cuticle treatment stick. The main part of the bag also holds two check books, 2 Rx bottles, coin purse for change, a credit card holder with 12 pockets, a RFID credit card holder and a large eyeglass cleaner the same size as a checkbook. The smaller outside zippered area is for my eye glasses which I change out with my sun glasses. The only drawback is when zipping or unzipping the large compartment you have to be very careful as the zipper can catch the beautiful apricot colored lining and I've done this 3 times. I have to really work gently to get it to release as I am afraid that it will tear the lining. I've been lucky so far so now I am more careful. I purchased the green bag and I love the color as well. I can also use this as a fannypack. Can't say enough about the quality of this bag. The safety features are absolutely wonderful. I will feel quite safe and secure on my trip this September to Italy. May 26, 2012
Like the bag I love PAC safe bags. This bag works for me but it is not a tote. More like a small pocketbook. I have it for a week in Europe. It will fit a small umbrella, a small wallet and a pair of glasses and a small scarf and cellphone. I fell safe carrying the bag which is why I purchased it. The bag is light and very comfortable. October 25, 2013
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Product:90833-Pacsafe Slingsafe 250 GII Handbag


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NE Senior Softball Web Site User Hints
The primary menu for navigating the web site is titled "Look Around". The top link there is "Who We Are", which gives a brief description of our league and serves as our site's home page, or "landing page". It also contains the Commish Corner, where content is provided by the League Commissioner. The following gives some hints for using a few of the pages listed in the Look Around menu.
This page contains the latest seasonal league information. It describes the current or upcoming season, its important dates, registration fees, and league structure. This page is updated for each season to keep current as dates and fees change from year to year. Each player in the league or prospective player should read through this information when its time to register for each season.
The Organization page identifies all of our league officers with a link to a page for each of our executive and director-level positions. The content for each of these pages is controlled by the responsible director and can be edited by them directly.
Current Games:
This page lists the scheduled games for the current play date. The current play date will be the current date, if it is a scheduled day of league play, or the date of the next game night if the current day is not a day of play. This page provides quick access for players to check the schedule for their next game. There is also a score column where winning team managers, when logged in, can click a link to add their scores once the game is over. This can easily be done at the field using a smart phone or tablet since this page is one of those accessible and formatted for those devices. In fact, this is the default landing page for the site when accessed by those devices.
Season at a Glance:
This page provides a matrix view of how each team has performed against each other team with their head-to-head win-loss record in each cell of the matrix. The matrix lists the teams across the top and down the side organized by divisions and ordered by the current standings within each division. Hover your mouse over each team's logo to see their current stats, including win-loss record (overall and divisional), games-back, and total runs (scored, against, and diff). Hover your mouse over each head-to-head win-loss record to see their game scores. Clicking on a team's logo will take you to the team's games page that shows their schedule for the season with scores of their completed games.
League News:
This page will list news items as they happen chronologically. This means they are only really "news" for a brief period, but they will stay on the page until purged (probably at the end of the season).
Managers Information:
This page contains links to information that team managers need to know, like the league rules and guidelines document and a description of manager responsibilities.
This page displays a list of teams in order of the current standings. There is a season filter drop-down menu to select which season you're looking for which defaults to the current or latest season. If the selected season has or had multiple divisions, these will be displayed in separate lists. Each team list will include the following columns:
- Division – identifies the division the team is in;
- Team Name – displays the name of the team as a link that takes you to a page with the team's list of scheduled games for that season; this column also has a ball player icon that is a link to the team's roster (the roster is simply the Players page described above that is pre-filtered for that team);
- Manager – displays the manager's name – click on the manger's name to get a pop-up window with his player info baseball card;
- W-L (and DIV WL) – shows the team's won-loss record (and win percentage in parentheses) based on the currently reported scores, keep in mind that scores don't always get reported to the web site immediately after games finish;
- GB – shows the number of games back the team is from the leader (within in the division, if applicable).
- RS – total runs scored
- RA – total runs scored against
- DIFF – RS minus RA
There is a link just below the season filter drop-down menu that takes you to a page that is formatted for easy printing. This page is also accessible more directly from smart phones or tablets from the main menu using the NE Senior Softball Standings link.
Tournament Teams:
This page displays identifies the age-bracketed tournament teams that are populated by league players. There is a menu bar with a button for each team that takes you to that team's page where their photos and accomplishments are on display.
This page displays the web site's calendar of games and other events. It starts in month-display format, but you can change it to a week-display or even a day-display using the links in brackets in the upper right. You can also click on the day of the month number in the upper right corner of each day cell to change to the day-display for that day. Hover your mouse over an event in the calendar (month-display only) to see a floating display with event details that are easier to read. Clicking on some events (not games) will take you to the event's page with more details. Regardless of which display format you are in (month, week, day), you can use the right and left pointing chevrons in the upper corners to advance to the next period or move back to the previous period.
This page displays a list of registered players that are in the site's database for a given season. You can use the team filter (drop-down selection menus) to pick the team of interest. If you select a specific team, the list displayed is the current roster for that team. Team managers are highlighted with a yellow background and players with an asterisk (*) to the left of their name are members of the "Juiced-Bat" club since they are old enough to play without bat restrictions. You can click on a player's name to get the player's info along with a photograph if one has been submitted for the site. This information will be displayed in a pop-up with the appearance of a baseball card (front side and back side). In the upper-right corner of the card, there is a player serial number in parentheses. When viewing one of these baseball card pop-ups, you can use the right and left facing chevrons in the lower corners to advance to the previous or next player in the current list being viewed. If your photograph does not appear on your player information card, you can send an electronic copy of your favorite head shot to the web master to be uploaded to the site.
Click "Register" in upper right to create a web site account: As a player with a web site account, you can edit your own personal information if you have have logged in. After logging in, if you navigate to the Players page and click on your name to see your pop-up baseball card, you should see an "[Edit]" link at the bottom of the stats side of the card (the right side). Clicking on that link will enable editing of the data fields so that you can update your contact and other information yourself. In order to see the "Edit" link on your player card, you must be logged in and the email address of your user account must match the email address that you specified when you registered with the league (i.e., the one shown on your card). If you make a change on your card, don't forget to click the "Save" button before you leave the page. If you mistakenly change something in error, click the "Cancel" button without clicking "Save" and all is forgotten. If you have trouble logging in or updating your player information, please email the web master.
Board Meetings:
This page displays a list of official board meeting documents that have been uploaded to the site by board members and/or the league secretary. The documents are listed by year and include all of our archives. Since 2011, these documents have been stored in PDF format for ease of downloading and reviewing using a PDF reader (Acrobat Reader). Prior to 2011, the meeting minutes were transposed onto web pages which are still accessible using the links at the bottom of the page under "Older Meeting Minutes". There is a mechanism on this page to upload files to be included in the list, but this action is password-protected to limit this page to official documents only.
The Games page is not listed in the Look Around menu, because its value is in the context of a particular team. So, it is accessed by clicking on a team name on the Teams page. This page displays a list of scheduled games for the selected team. The list shows When the game was/will be played, the Home team, the Visitor team, which Field number, and, if it has been played, the reported results of the game. The selected team's logo will be highlighted with a yellow background in the Home or Visitor column.
Score Keeping
Team managers will be responsible for updating the scores in the league database using the web site. I suggest that it primarily be the responsibility of the winning team's manager to enter the game score.
In order to do this, all team managers must be registered with a login account on the web site. Once you have created your account, it will be updated to enable you to enter scores. If you are a team manager, please find the time to register so you can enter scores.
If you are logged in, and you navigate to your team's game list, you will see an "add" link in the Score column after the scheduled game time has passed. Only those of you with the proper privilege will see the link, and it only shows up when the game time is in the past. In addition to the runs scored for each team, there is a Notes field in which you can enter a brief comment for display in the Games page if it makes sense. Comments/notes will not be common, but could be used for things like "called for time", "rained out", "called for lightning", etc.
To enter scores from a computer: (EASY)
- Navigate to neseniorsoftball.com in your computer's web browser, lands on Who We Are page
- Login to the site
- click on Teams in the "Look Around" menu to get the list of teams
- click on your team name in the Teams list to get your list of games
- find a game that has been played and click the "add" link under the Score column
- a screen is displayed where you enter the scores (and comment if necessary) and click Update button
To enter scores from a mobile device (even at the field!!): (EASIER)
- Navigate to neseniorsoftball.com in your device's web browser, lands on Current Games page
- Login by touching "Login" next to the main "Menu" tab when the menu is expanded
- touch on Teams in the site menu to get the list of teams
- touch on your team name in the Teams list to get your list of games
- find a game that has been played and touch the "add" link under the Score column
- a screen is displayed where you enter the scores (and comment if necessary) and touch Update button
To enter scores from a mobile device on game night: (EASIEST!)
- Navigate to neseniorsoftball.com in your device's web browser, lands on Current Games page
- Login by touching "Login" next to the main "Menu" tab when the menu is expanded
- touch the "add" link under the Score column of your game
- a screen is displayed where you enter the scores (and comment if necessary) and touch Update button


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Jamie Dimon
Keith Bedford/Reuters
News about Jamie Dimon, including commentary and archival articles published in The New York Times.
Chronology of Coverage
Jul. 2, 2014
Corporate leaders have wrestled with how — or whether — to go public about health problems. How much to disclose, and when, involves delicate corporate and personal decisions for which there are few hard rules. MORE
Jul. 1, 2014
In an email to the bank's employees and shareholders, Mr. Dimon said that doctors discovered the cancer at an early stage. MORE
Feb. 9, 2014
A top Chinese regulator directly asked Jamie Dimon, the bank's chief executive, for a "favor" to hire a young job applicant, a confidential email shows. The applicant, a family friend of the regulator, now works at JPMorgan. MORE
Feb. 1, 2014
James B Stewart Common Sense column on decision by JPMorgan Chase's board to award chief executive Jamie Dimon compensation of $20 million, or 74 percent raise, for year in which bank narrowly escaped criminal guilty plea and paid more than $20 billion in regulatory fines and penalties; says in world of Wall Street executive compensation, pay raise recommended for Dimon is not only defensible, but laudable. MORE
Jan. 23, 2014
In a series of contentious meetings, JPMorgan Chase's board voted to give Jamie Dimon a new pay package after his pay was cut in half last year, to $11.5 million. MORE
Oct. 20, 2013
A tentative $13 billion settlement between JPMorgan and the Justice Department was a result of extensive personal outreach from Jamie Dimon, the bank's chief executive, to the Justice Department. MORE
Oct. 20, 2013
Mounting legal problems have so far left Jamie Dimon unscathed at the helm of JPMorgan Chase. MORE
Sep. 26, 2013
Jamie Dimon, the chief executive of JPMorgan Chase, met with the attorney general to discuss a deal that would involve a fine of more than $7 billion, plus $4 billion in relief for struggling homeowners. MORE
Sep. 21, 2013
Joe Nocera Op-Ed column recounts how JPMorgan Chase went from best-managed bank with an admirable chief executive in Jamie Dimon to becoming a pinata for government regulators, racking up total of $1.3 billion in fines in one day; contends reason is bank was never as well-managed as it appeared and now regulators are finally getting serious. MORE
May. 26, 2013
Jeff Sommers Strategies column observes that JPMorgan Chase shareholders approved dual role of Jamie Dimon as chief executive officer and chairman, while Apple's chief Timothy D Cook received praise from senators at a hearing on firm's strategies to avoid taxes. MORE
May. 22, 2013
JPMorgan Chase is redoubling its efforts to move beyond a big trading loss following a resounding shareholder endorsement to keep Jamie Dimon as both chairman and chief of the bank. MORE
May. 21, 2013
A JPMorgan Chase shareholder resolution to split the chairman and chief executive roles became a referendum on Jamie Dimon himself. It was a test he easily passed. MORE
May. 19, 2013
If shareholders separate the jobs of chairman and chief executive — positions that Jamie Dimon has held since 2008 — it would signal a shift in the balance of power in corporate America. MORE
May. 14, 2013
As he wrestles with the fallout of a bungled trade, Jamie Dimon, the chief of JPMorgan Chase, has sought advice from a banker familiar with tumult: Lloyd C. Blankfein. MORE
May. 13, 2013
It may not be popular to say, but the incontrovertible fact remains that JPMorgan Chase has remained one of the best-performing banks on Wall Street under Jamie Dimon. MORE
May. 9, 2013
Op-Ed article by Prof Jeffrey A Sonnenfeld criticizes those who want to separate jobs of chairman and chief executive officer at banks, and attack Jamie Dimon for holding both positions at JPMorgan Chase; contends there is no evidence to suggest that anything would be gained by separating roles, which can even add to confusion over responsibilities and voice. MORE
Apr. 29, 2013
The turnover at the highest levels of the bank continues just weeks before a shareholder vote decides whether to split the roles of chairman and chief executive. MORE
Apr. 5, 2013
Board members are making an unusual effort to persuade investors that JPMorgan Chase's chief, Jamie Dimon, should keep his chairman title amid fallout from a trading loss. MORE
Feb. 27, 2013
JPMorgan Chase chief executive Jamie Dimon vows to change how the bank deals with Internet-based payday lenders that automatically withdraw payments from borrowers' checking accounts. MORE
Jun. 14, 2012
Editorial criticizes members of the Senate Banking Committee for their soft-ball treatment of JPMorgan Chase head Jamie Dimon during a hearing on the bank's massive trading loss; notes that Dimon appeared anything but contrite during the proceedings; contends that until lawmakers commit to tougher regulations on proprietary trading, the financial system will continue to be vulnerable to the hubris and recklessness of big banking. MORE
May. 17, 2012
Editorial scores Jamie Dimon and his co-executives at JPMorgan Chase for continuing to push for weakened form of the Volcker Rule, which is meant to bar banks from making risky trades with their own capital; argues bank's $2 billion loss leaves no doubt that regulators must shore up the Volcker Rule so that it strictly limits such hedging. MORE
May. 16, 2012
Maureen Dowd Op-Ed column submits JPMorgan Chase head Jamie Dimon has gone from being the great defender against tougher bank regulations to being the shining example of why still tougher regulations may be needed, in light of bank's $2 billion trading blunder. MORE
May. 13, 2012
Gretchen Morgenson Fair Game column contends the $2 billion trading loss disclosed by JPMorgan Chase shows how the tables have turned on the bank and its chief executive Jamie Dimon, an industry point man against tighter regulation; points out the loss comes just a month after a private dinner party at which he assailed Paul Volcker and Federal Reserve Bank of Dallas president Richard W Fisher, who have pushed for policies that would make banks like JPMorgan smaller and less risky. MORE
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Highlights From the Archives
Jamie Dimon: America's Least-Hated Banker
During the financial crisis, the C.E.O. of JPMorgan Chase outshone his rivals. But where exactly does that leave him now?December 5, 2010 magazineNews
After Crisis, Show of Power From JPMorgan
For all Jamie Dimon's gloomy talk, the future for JPMorgan Chase is looking bright after the credit crisis.July 15, 2010 businessNews
In Washington, One Bank Chief Still Holds Sway
With the financial crisis, Jamie Dimon, the head of JPMorgan Chase, has become more politically engaged and in the process, the most credible voice of a discredited industry.July 19, 2009 businessNews
Eric Holder's Mixed Legacy on White-Collar Crime
Mr. Holder's tenure as attorney general was marked by multibillion-dollar settlements with big banks but few prosecutions of executives.
September 29, 2014, Monday
MORE ON JAMES DIMON AND: Breuer, Lanny A , Dimon, James , Holder, Eric H Jr , Mozilo, Angelo R , Stevens, Ted , Alaska , American International Group Inc , Bank of America Corporation , BNP Paribas , Countrywide Financial Corp , JPMorgan Chase & Company , Justice Department , Residential Mortgage-Backed Securities Working Group , UBS AG , Attorneys General , Banking and Financial Institutions , Fines (Penalties) , Securities and Commodities Violations , Subprime Mortgage Crisis
Banks Did It Apple's Way in Payments by Mobile
The eagerness of banks and card companies to work with Apple on its mobile payment system suggests Apple's clout and the concern financial players have for their future.
September 11, 2014, Thursday
MORE ON JAMES DIMON AND: Anderson, James , Cook, Timothy D , Dimon, James , Lake, Marianne , American Express Company , Apple Inc , JPMorgan Chase & Company , MasterCard Inc , Visa Inc , Banking and Financial Institutions , Credit Cards , Mobile Commerce
MetLife's Low Profile May Work to Its Advantage
It's understandable if MetLife objects to being labeled a systemically important financial institution, an action that's likely later this week. But public disputes with regulators are never advisable, Rob Cox writes for Reuters Breakingviews.
July 29, 2014, Tuesday
MORE ON JAMES DIMON AND: Bernanke, Ben S , Frank, Barney , Collins, Susan M , Dimon, James , Office of Thrift Supervision , Financial Stability Oversight Council , JPMorgan Chase & Company , MetLife Inc , Federal Reserve System , Regulation and Deregulation of Industry , Insurance , Dodd-Frank Wall Street Reform and Consumer Protection Act (2010)
Banks Cash In on Inversion Deals Intended to Elude Taxes
Wall Street banks are estimated to have collected, or will soon collect, nearly $1 billion in fees over the last three years advising and persuading American companies to move the address of their headquarters abroad.
July 28, 2014, Monday
MORE ON JAMES DIMON AND: Corporate Taxes , Tax Shelters , Goldman Sachs Group Inc , Relocation of Business , Banking and Financial Institutions , Dimon, James
JPMorgan's Second-Quarter Numbers a Hopeful Sign for Economic Growth
JPMorgan Chase's results exceeded analyst expectations even as the bank grappled with lackluster revenue from trading and a slowdown in mortgage lending.
July 15, 2014, Tuesday
MORE ON JAMES DIMON AND: Dimon, James , JPMorgan Chase & Company , Company Reports , Banking and Financial Institutions
Dimon's Cancer and the Fine Line in Revealing Illness of a C.E.O.
Corporate leaders have wrestled with how — or whether — to go public about health problems. How much to disclose, and when, involves delicate corporate and personal decisions for which there are few hard rules.
July 2, 2014, Wednesday
MORE ON JAMES DIMON AND: JPMorgan Chase & Company , Executives and Management (Theory) , Dimon, James , Medicine and Health
JPMorgan's Jamie Dimon Has Throat Cancer That He Calls 'Curable'
In an email to the bank's employees and shareholders, Mr. Dimon said that doctors discovered the cancer at an early stage.
July 1, 2014, Tuesday
MORE ON JAMES DIMON AND: Dimon, James , Cancer , JPMorgan Chase & Company
Wall Street Washes Traders' Mouths With Soap
A string of recent regulatory crackdowns has opened a window into the locker room culture of finance. Some banks are now taking steps to clean up that culture.
May 16, 2014, Friday
A Dinner Among Survivors of the Financial Crisis
At a charity event on Wednesday, the chief of Goldman Sachs was overheard recounting a dinner with Jamie Dimon and Peter Sands, where they traded stories from the dark days of 2008.
May 1, 2014, Thursday
MORE ON JAMES DIMON AND: Blankfein, Lloyd C , Pandit, Vikram S , Lewis, Kenneth D , Mack, John J , Diamond, Robert E Jr , Dimon, James , JPMorgan Chase & Company , Morgan Stanley , Standard Chartered Bank PLC , Barclays PLC , Citigroup Inc , Goldman Sachs Group Inc , Bank of America Corporation , Philanthropy , Banking and Financial Institutions
Bank of America Not Alone in Reporting Anemic Results
Bank of America's $276 million loss provides some valuable perspective on the difficulties in running a big bank these days, Antony Currie of Reuters Breakingviews writes.
April 16, 2014, Wednesday
MORE ON JAMES DIMON AND: Corbat, Michael L , Dimon, James , Moynihan, Brian T , Citigroup Inc , JPMorgan Chase & Company , Bank of America Corporation , Company Reports
U.S. markets climb slow but steady
Summary: Private sector job creation leads U.S. markets to new records; JPM down on Jamie Dimon health announcement; GoPro takes its first tumble; FTC sues T-Mobile; Goldman a "boys" club? Lily Jamali reports.
Who'll succeed Jamie?
JPMorgan CEO Jamie Dimon says he has been diagnosed with curable throat cancer, but that hasn't stopped Wall Street from guessing who might eventually replace him. Fred Katayama reports.
JPMorgan's profit plunges 19 pct
A slump in fixed income trading and slowdown in mortgage loans slammed JPMorgan Chase's income. But CEO Jamie Dimon voiced optimism. Fred Katayama reports.
Who Will Replace Jamie Dimon?
The departure of Michael Cavanaugh, a heir apparent at JPMorgan Chase, has set off a new round of speculation about who could ultimately succeed Jamie Dimon.
JPMorgan Chief on China Inquiry
In the interview with Andrew Ross Sorkin on CNBC, Jamie Dimon played down the significance of hiring well-connected applicants.
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Alexandra's Q & A
Favorite Sport/Team
Soccer! (use to play for years)
Favorite Movie/Actor
Fight Club "first rule of fight club you do not speak about fight club" love it
Go-to karaoke song
Whitney Houston's "I will always love you" I can actually sing but does the shower count?
My first job
JcPenny's Photographer
Piercings/Tattoos (How many? Where?)
four tattoo's one on my right wrist, one on my right booty check, one on my left hip, and one on but behind my left ear. ears and right ear cartilage piercing
Mac or PC?
well...Mac for Ipad but PC for everything else
Nintendo, Xbox 360, PS3, or don't game?
Nintendo all the way! I love classic Nintendo games like Mario and Zelda my favorite though is Mario kart for some reason I always lean which ever way my car is also leaning.
What fun fact, talent or superpower of yours should guys know about?
fun fact: I am one of the biggest nerds you will ever meet in every sense of the definition, Talent: I am actually a pretty good singer and superpower: I have the superpower of being able to seem interested in something when I'm really not
What's the most memorable pick up line you've ever heard?
LOL so many to choose from but I would have to say the most memorable one was "are you from Tenseness?.....cuz your the only TEN-I-SEE!" classic!
What's the craziest thing you've ever done?
mountain biking I've gotten better but I manged to take out a few tree branches with me.
What's the most unusual place you've ever hooked up? How'd it go?
the parking lot of a funeral home (in the car) almost got arrested hee hee hee
What's in your purse or pocket right now?
oh man a whole lot of junk...my wallet, a brush, perfume,chap stick (you know all the girlie stuff) and my micro dessert eagle
What do you feel most comfortable wearing?
a bathing suite, I can't wait for summer to arrive
Would you rather have boring sex all the time or an amazing romp once a year?
oh man! what a difficult question, but I guess I would have to say boring sex I become evil if I do get mine LOL
If you could do a shot of Jose Cuervo with anyone -- dead or alive -- who would it be?
William Shakespeare he would probably say the best toast ever


text:
Please begin typing, and select your location from the list
Get better results and save time by saving your locations. Home, Office, Favorite vacation spot, Grandmas House and more...Create an account | Log In
Recently Searched locations
Popular locations
2293 Delaware Ave
Buffalo, NY 14216
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Categories: Pet Grooming & Boarding Kennels, Pet Care
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© 2014 Local Corporation - US Patent 7,231,405
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text:
Sponsored by Tennis (women)
The Luther women's tennis team played its second straight match at the Winona Tennis Center in Winona, Minn., due to bad weather conditions.
Tonight, the Norse posted a 6-3 victory over the Augustana Vikings. The Norse gathered a pair of doubles points and then won four of the six singles matches to grab the team victory.
Lola White-Baer and Hailey Johnson improved to 6-0 this spring with an (8-2) victory over Miranda Pence and Caitee Margenthaler at No. 3 doubles, giving Luther a quick 1-0 advantage. Katy Lindstrom and Annie Whiteley went down an early break at No. 2, but broke back and then picked up a couple more breaks on the way to an (8-3) win against Krista Panko and Meghan Wethington. Augustana tallied its first point with an (8-5) decision at No. 1 where Kim Sawyer and Aileen MacDonald outlasted Luther's Elise Allen and Maggie Helms.
Leading 2-1, the Norse extended the lead with another win from White-Baer, as she made quick work of Emily Kaczmarek at No. 2 by a (6-3, 6-0) score. MacDonald knocked off Lindstrom (6-3, 6-3) at No. 4 as the Vikings closed within 3-2, but Jenna Myers defeated Wethington (7-6 (3), 6-3) at No. 6 to make it 4-2. Helms clinched the match for the Norse with a hard fought (7-5, 6-3) win against Panko at No. 3. Allen lost a (6-4, 6-3) battle at No. 1 to Sawyer before Whiteley outlasted Pence (6-2, 4-6, 6-3) at No. 5 to account for the final 6-3 margin.
The Norse improve to 15-7 overall this season. Luther will face Wartburg in the semi-finals of the Iowa Conference Automatic Qualifier tournament in Cedar Rapids, Iowa on Saturday, April 27.
Eagan, Minn.
Lakeville, Minn.
Lakeville North
Wayzata, Minn.
Iowa City, Iowa
First Year
Moline, Ill.
First Year
Centennial, Colo.
Arapahoe High School
First Year
Cedar Rapids, Iowa
Questions? Contact David Blanchard, post_to_results, 563-387-1586


text:
Main Office:
Child Protection Center, Inc.
720 South Orange Ave.
Sarasota, Florida 34236
Phone: 941.365.1277
Venice locations:
2210 S. Tamiami Tr.
Venice, Florida 34293map
North Port Location:
6919 Outreach Way
North Port, Florida 34297
Arcadia Location:
222 N. Roberts Avenue
Arcadia, Florida 34266
© 2011 Child Protection Center, Inc. Sarasota Florida.
All rights Reserved. Privacy
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