text:
Studies Make Case for Finasteride to Prevent Prostate Cancer
The initial results from the largest completed prostate cancer prevention trial appear to have underestimated the benefits and overestimated the potential risks of finasteride, according to three new analyses of data from the trial. These results bolster the case for finasteride as a preventive agent against prostate cancer, say the studies' leaders.
Results from two of the analyses were presented on May 18 at the American Urology Association annual meeting in Orlando, FL, and all three appeared online May 18 in Cancer Prevention Research. Read more
Potent Social Forces Influence Smoking Behavior
Friends and family have a powerful influence on whether a person quits smoking, and the decision to stop smoking can "spread" from one person to another in a social network, new research suggests. The findings are from a detailed analysis of smoking behavior in more than 12,000 individuals who were followed for 32 years, from 1971 to 2003, as part of the Framingham Heart Study.
In 1971, the places smokers and nonsmokers held in the social network were indistinguishable. But three decades later, societal views of smoking have changed, and smokers are increasingly at the periphery of social networks and aligned largely with other smokers, according to results published in the May 22 New England Journal of Medicine. Read more
Studies Make Case for Finasteride to Prevent Prostate Cancer
The initial results from the largest completed prostate cancer prevention trial appear to have underestimated the benefits and overestimated the potential risks of finasteride, according to three new analyses of data from the trial. These results bolster the case for finasteride as a preventive agent against prostate cancer, say the studies' leaders.
Results from two of the analyses were presented on May 18 at the American Urology Association annual meeting in Orlando, FL, and all three appeared online May 18 in Cancer Prevention Research.
Initial results from that trial, the nearly 19,000-participant Prostate Cancer Prevention Trial (PCPT), were published in 2003 and showed that men who took 5 mg of finasteride daily for 7 years had a 25 percent reduced risk of developing prostate cancer compared with men taking a placebo.
However, finasteride treatment was also associated with a small but statistically significant increased risk for developing high-grade prostate cancers, those with Gleason scores of 7 to 10. And because the preventive benefit was the result of a reduction of non-high grade cancers, those with a Gleason score of 6 or less, some prostate cancer researchers argued that finasteride only prevents indolent cancers that would never require treatment, explains Dr. Ian Thompson, chair of the Department of Urology at the University of Texas Health Science Center at San Antonio and a senior author on two of the new analyses.
Neither conclusion, he says, now appears to be accurate.
"We've now shown that the cancers prevented by finasteride are often clinically significant, the same kind of cancers that lead to surgery," Dr. Thompson says. "In addition, we showed a 28 percent reduction of high-grade cancer with finasteride."
In a related editorial in Cancer Prevention Research, Drs. Christopher Logothetis and Paul Schellhammer, from University of Texas M.D. Anderson Cancer Center and Eastern Virginia Medical School, respectively, lauded the analyses, arguing that the results demonstrate that "the promise of prostate cancer prevention is a reality."
Two of the analyses were conducted independently, using 500 prostatectomy samples from the more than 2,000 patients diagnosed with cancer in the PCPT, to estimate the "true rate" of high-grade disease in the two study arms (finasteride and placebo). The analyses, one led by Dr. Mary Redman from Fred Hutchinson Cancer Research Center and the other by NCI's Dr. Paul Pinsky, used statistical modeling to extrapolate the Gleason scores at prostatectomy to the larger study population. Prostatectomy is the gold-standard for determining Gleason scores. Both analyses adjusted for the fact that, as recent studies have shown, finasteride increases the sensitivity of both prostate-specific antigen (PSA) testing and needle biopsy for detecting high-grade cancer.
No overall increase in high-grade disease associated with finasteride was found by either analysis, Dr. Thompson stresses. Instead, they found that finasteride had a modest protective effect, driven by the reduction in tumors scored as Gleason 7. Because of the limited number of cancers scored as Gleason 8 to 10, says Dr. Howard Parnes from NCI's Division of Cancer Prevention, it's not possible to draw firm conclusions about finasteride's affect on such tumors.
The third analysis, conducted by Dr. Scott Lucia from the University of Colorado Denver and colleagues, addressed whether finasteride prevents "clinically significant" prostate cancer by examining the extent of cancer present in the PCPT biopsy specimens of Gleason score 6 cancers - again, the cancers that finasteride was shown to inhibit in the PCPT. They assessed biopsy samples according to two different sets of criteria that can be used to guide treatment decisions. Sixty percent of tumors given a Gleason score of 6 or less were clinically significant by these criteria.
More than 90 percent of men whose prostate biopsies have Gleason scores of 6 opt to receive immediate treatment, explains Dr. Parnes, a co-author on two of the analyses. So, regardless of whether they would be considered clinically significant by these biopsy criteria, he says, "We shouldn't overlook the importance of preventing the so-called 'clinically insignificant' tumors."
Finasteride is not yet approved by the Food and Drug Administration (FDA) for prostate cancer prevention, Dr. Parnes cautions. "However, men committed to regular screening and those with benign prostatic hyperplasia (BPH) may want to discuss this option with their physicians," he adds. Finasteride is FDA-approved for treating BPH symptoms and, at a lower dose, for reducing hair loss.
FDA approval aside, there are other factors holding finasteride back, says Dr. Brantley Thrasher, chair of Urology at the University of Kansas Medical Center.
Urologists have become "acclimated" to the idea that finasteride increases the risk of high-grade disease, he says. And it's more than that. "Nobody has worked out which patients we should be recommending finasteride to," Dr. Thrasher adds. "I think it will be an uphill battle to get wider adoption."
The AUA and American Society of Clinical Oncology are in the process of developing guidance on finasteride use for prostate cancer prevention, Dr. Parnes says.
—Carmen Phillips
Potent Social Forces Influence Smoking Behavior
In 1971, the places smokers and nonsmokers held in the social network were indistinguishable. But three decades later, societal views of smoking have changed, and smokers are increasingly at the periphery of social networks and aligned largely with other smokers, according to results published in the May 22 New England Journal of Medicine.
The authors, Drs. Nicholas Christakis of Harvard Medical School and James Fowler of the University of California, San Diego, reported last year that social networks may strongly influence obesity. In the current study, the authors demonstrate that decisions to quit smoking often reflect changes made by groups of people connected to each other, both directly and indirectly. For example, when a spouse quit smoking, the partner's chances of smoking decreased by 67 percent; friends who quit smoking decreased one another's chance of smoking by 36 percent.
The network phenomenon could potentially be exploited to spread positive health behavior, the study concludes. Along these lines, collective interventions may be more effective than individual interventions, and public health strategies to encourage smoking cessation may be more cost-effective than initially thought, since health improvements in one person may well spread to others.
MRI May Contribute to Rising Mastectomy Rates
The number of mastectomies performed at the Mayo Clinic in Minnesota for women with early stage breast cancer jumped by 13 percent between 2003 and 2006, rising from 30 percent to 43 percent. A new study suggests that the introduction of preoperative breast magnetic resonance imaging (MRI), which is more sensitive than traditional mammography, may have been a factor.
An analysis of more than 5,400 women with early stage breast cancer who had surgery at the Mayo Clinic between 1997 and 2006 showed that women who received preoperative MRI were significantly more likely to undergo mastectomy than those who did not, though mastectomy rates rose in both groups. Co-author Dr. Matthew P. Goetz recently briefed the media on the findings, which will be presented next month at the American Society of Clinical Oncology annual meeting.
Preoperative breast MRI can detect cancer in more than one part of the breast, and this may lead physicians and patients to choose mastectomy over lumpectomy. About half of the lesions detected by MRI are not cancerous and only need to be monitored, but some women with these lesions may still choose mastectomy for various reasons, according to the researchers.
Mastectomy rates declined from 45 percent in 1997 to 30 percent in 2003, but then rose to 43 percent in 2006, the study found. During this period, the percentage of women who had breast MRI doubled to 22 percent. Half of the patients receiving MRI underwent mastectomy, compared with 38 percent of women who did not have MRI. Mastectomy rates also rose in women who did not have preoperative MRI (from 28 percent in 2003 to 41 percent in 2006).
Dr. Julie Gralow of the University of Washington, who moderated the briefing, cautioned that more research is needed to determine whether the additional surgeries improve outcomes and increase overall survival. A recent study showing an increase in preventive double mastectomies has similarly raised questions about the risks and benefits of these surgeries.
BRCA2 Linked to Prostate Cancer Incidence and Aggression
A study by researchers in Australia and Canada shows that BRCA2 mutation-positive men from BRCA mutation-positive families are at 3.5 times the risk of developing prostate cancer, and at higher risk of aggressive prostate cancer, compared with the general population. No increase in prostate cancer risk was observed in BRCA1 mutation-positive men in this study. The report appeared in the May 15 issue of Clinical Cancer Research.
The researchers examined 137 families that were known to have germline BRCA1 or BRCA2 mutations and that also had at least one male member who was diagnosed with prostate cancer. Among these families, 158 such men were candidates for the study. Lack of available prostate biopsies limited the analysis to 18 prostate cancer patients, 4 of whom carried germline BRCA1 mutations and 14 with germline BRCA2 mutations.
Loss of heterozygosity - in which one copy of a defective gene is inherited and the other copy becomes defective some time after birth, perhaps due to environmental factors - was detected in the prostate tumor tissue from 10 of the 14 BRCA2 carriers. The men whose cancers displayed loss of heterozygosity had exceptionally high Gleason scores of 7 to 9 (the median score was 9), and they had stage II or higher cancers.
"Although the sample size is small," the authors wrote, "these results indicate that BRCA2 has the hallmarks of a tumor suppressor and is the likely cause of the prostate cancer in a substantial portion of carriers who are diagnosed with the disease." The data add to prior information suggesting that prostate cancer may be part of the hereditary breast/ovarian cancer syndrome. The researchers added that there are no data to support a mechanism by which BRCA2 may cause prostate cancer.
The authors noted that BRCA2 mutation-positive (but not BRCA1 mutation-positive) men from hereditary breast/ovarian cancer families should be considered at significantly increased risk of prostate cancer by clinicians responsible for their care. They also suggest that additional evidence is required to formulate the specific screening advice and optimal management recommendations required to reduce the burden of prostate cancer in genetically at-risk men.
Vitamin D Not Associated with Decreased Prostate Cancer Risk
In a nested case-control study of participants from the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial, published online May 27 in the Journal of the National Cancer Institute, higher concentrations of serum 25-hydroxy vitamin D [25(OH)D], the primary form of vitamin D circulating in the bloodstream, were not associated with a decreased risk of prostate cancer. In fact, concentrations greater than the lowest fifth of the spectrum tended to be associated with an increased risk of aggressive disease.
Researchers in NCI's Division of Cancer Epidemiology and Genetics collected data on serum 25(OH)D concentrations from 749 white men diagnosed with prostate cancer and 781 controls, from samples taken at the beginning of their participation in the PLCO study (at baseline). All participants were taken from the PLCO trial screening arm, which includes annual standardized prostate cancer screening.
Serum 25(OH)D concentration was not associated with risk for prostate cancer overall, nor with non-aggressive disease; however, the researchers did see some evidence of an increased risk of aggressive disease associated with higher concentrations of vitamin D. They note that in their analyses not all the trends were statistically significant nor did the associations generally show a linear dose-dependence.
"In summary, results from this large prospective study of men who underwent standardized prostate cancer screening in the context of a screening trial do not support the hypothesis that higher serum vitamin D status is associated with decreased risk of prostate cancer," state the authors in an accompanying press release. "It raises the possibility that higher vitamin D level may be associated with increased risks for aggressive disease, [but] a clear monotonic dose-response relationship was lacking."
Guest Update by Dr. Daniela S. Gerhard
TCGA Moving Molecular Oncology Forward
The Cancer Genome Atlas (TCGA), a collaborative project between NCI and the National Human Genome Research Institute (NHGRI), is at the mid-point of its 3-year pilot phase. The TCGA pilot is a truly integrative, multidisciplinary effort to develop and assess a framework for systematically identifying and characterizing the genomic changes associated with three cancer types: brain cancer (glioblastoma multiforme, or GBM), lung cancer (squamous cell carcinoma of the lung), and ovarian cancer (serous cystadenocarcinoma of the ovary).
Already we are beginning to see the value of this project. Not only are new data being developed and shared with researchers around the world, but new technologies and tools are being developed that are allowing researchers to delve further into the molecular machinery of cancer with greater precision and efficiency.
For example, multiple technology platforms are being used at TCGA for molecular characterization and sequencing to interrogate tumor samples and their corresponding normal samples, ensuring that the data for each case are incredibly rich and as complete as possible. As the centers gain experience with some of the newer platforms, they learn how best to use them, both in terms of producing quality data as well as cost efficiency.
The different centers at the core of TCGA - which focus on characterization, sequencing, data collection and informatics, and technology development - are working in close concert integrating different data types, such as gene-expression signatures, microRNA-expression signatures, and methylation patterns, looking for new and more powerful ways to stratify tumors by subtypes, each of which may have different prognoses and require different treatment approaches. These data are then used to identify specific genes to sequence. The project team has designed TCGA to provide biomolecules (RNA and DNA) from a central facility to all TCGA centers to ensure uniform quality of the material.
To date, efforts with GBM are the furthest along, with more than 234 tumor cases (out of a planned 500) having undergone comprehensive characterization and a subset sequencing of 1,300 genes. This work is providing valuable insights into the biology of GBM and identifying potential new treatment avenues.
One example is an expanded understanding of the key signaling pathways involved in GBM. The integration of characterization data from the different TCGA labs has shown that not only is p53 - an important tumor suppressor gene - mutated more often in GBM than previously believed, but also that other key genes in the p53 pathway are often mutated, such that as many as 80 percent of GBM cases appear to have potentially important mutations in this pathway.
These findings suggest that other genes "downstream" of p53 could be valuable therapeutic targets. And this is just the first signaling pathway in GBM to be better elucidated.
It's important to stress that all TCGA centers have to immediately submit their raw data to the Data Coordinating Center, a database that is part of the cancer Biomedical Informatics Grid. The data are available to the scientific community, and all interested parties must sign agreements meant to strictly protect patient confidentiality.
The public spotlight is once again heavily focused on cancer, particularly brain cancer, following the malignant glioma diagnosis given to Senator Edward Kennedy, a long-time advocate for cancer research. Unfortunately, little progress has been made over the past several decades in the early detection and treatment of GBM. Our hope is that TCGA will help change that, allowing researchers to identify new methods for early detection, diagnosis, and treatment of GBM and the other cancers, and, in the process, recognize the true promise of molecular oncology.
Dr. Daniela S. Gerhard
Following are newly released NCI research funding opportunities:
SBIR Phase II Bridge Awards to Accelerate the Development of New Cancer Therapies and Cancer Imaging Technologies toward Commercialization
Letter of Intent Receipt Dates: Aug. 19, 2008; Jan. 27, 2009.
This funding opportunity will use the R44 award mechanism. For more information see http://researchportfolio.cancer.gov/initiativedetail.jsp?InitiativeID=3884. Inquiries: Dr. Andrew J. Kurtz - email@example.com.
A New Cancer Specialty: Follow-up for Long-term Survivors
Diagnosed with inoperable Hodgkin lymphoma in 1978 at age 21, Eileen Gould received what was then state-of-the-art treatment: massive doses of radiation to the chest, abdomen, and pelvis. In addition, her spleen was removed. The treatment cured her lymphoma, which has never recurred.
Years later, she recounts, she was plagued by persistent fatigue and lack of endurance. Climbing a flight of stairs left her winded. Several doctors could find nothing wrong. Then she stumbled on an early online support group for long-term survivors of Hodgkin lymphoma, many of whom reported symptoms similar to hers.
"I thought, oh my gosh, I'm not crazy after all," says Eileen, 51, who lives in New York City. Nearly 20 years after her lymphoma diagnosis, a cardiologist confirmed that she had heart damage caused by large doses of radiation to her chest. Today Eileen lives with multiple chronic and late effects from the treatment that saved her life, including early menopause, hypothyroidism, chronic orthostatic hypotension, and a compromised immune system due to the removal of her spleen. She's had basal-cell skin cancers and in situ (noninvasive) breast cancer.
Decades of research on survivors of childhood cancer have shown that the effects of cancer and its treatment can last a lifetime. The nature of these effects varies widely and depends on many factors, including the type of cancer treated, the way it was treated, and the patient's age when treated. More recently, studies have begun to document long-term and late effects of cancer treatments in cancer survivors diagnosed and treated as adults. A 2005 Institute of Medicine report, From Cancer Patient to Cancer Survivor: Lost in Transition, noted that few survivors currently receive comprehensive, coordinated long-term follow-up care. Such care may reduce the occurrence or severity of late effects through screening and appropriate preventive or early interventions.
Many children's hospitals and cancer centers with pediatric oncology programs have long had dedicated follow-up clinics for survivors of childhood and adolescent cancer, but these programs often follow survivors only until they reach their early 20s. To date at least eight new programs, supported by grants from the Lance Armstrong Foundation as Survivorship Centers of Excellence, have been created around the country that focus on the needs of older survivors and on long-term follow-up for survivors of cancer diagnosed in adulthood. Eileen Gould is a patient of one such program, located at Memorial Sloan-Kettering Cancer Center (MSKCC).
Although the structure of these programs varies, common features include leadership by a doctor knowledgeable about cancer late effects, state-of-the-art screening tailored to each patient's specific late-effect risks, referrals to appropriate specialists, wellness education, and research to better characterize not only the follow-up care needs of long-term cancer survivors but also the most effective approaches to providing that care.
"Post-treatment care is a new and evolving area of research," says Julia Rowland, director of NCI's Office of Cancer Survivorship. "We are only just developing the evidence base for what long-term follow-up care should look like. Examining the impact of such programs on the cost of care, and more importantly on survivors' ultimate health-related and quality-of-life outcomes, must be a critical part of this research."
A challenge for many long-term cancer survivors is lack of access to the records documenting the treatment they received. Eileen is fortunate to have all of her records, which her oncologist sent to her when he retired from practice. Using these records, Dr. Kevin Oeffinger, her physician and director of the MSKCC program for adult survivors of childhood and adolescent cancer, prepared a plan for her that documents the type of cancer she was treated for, the doses of radiation she received, the long-term or late effects that can result from that treatment, and the types and frequency of screening and monitoring she should receive. This approach is in line with what the IOM report described as "survivorship care plans," which it recommended for every cancer patient completing primary treatment.
"It's enormously helpful when I go to see my other doctors," says Eileen.
An avid tennis player before her cancer diagnosis, Eileen says she still enjoys an occasional doubles match. Despite her many health challenges, she says she's grateful to have survived this long. "I was so happy when I reached my 50th birthday - I never thought it would happen."
—Eleanor Mayfield
House Panel Holds Hearing on Breast Cancer and Environment Legislation
The U.S. House Energy and Commerce Subcommittee on Health held a May 21 hearing on legislation (H.R. 1157) to foster additional research at NIH on the possible environmental causes of breast cancer. Subcommittee Chairman Frank Pallone (D-NJ) noted that the legislation had been introduced in several previous Congressional sessions, and he and the sponsors of the bill hoped it would be passed without further delay.
Dr. Deborah Winn, chief of the Clinical and Genetic Epidemiology Research Branch in NCI's Division of Cancer Control and Population Sciences, testified that although the House bill is "well intended," it could have the "unintended consequence of narrowing the field of inquiry and promoting an unwise use of precious resources by mandating a specific way of conducting Federal research in breast cancer."
She stated that NIH and NCI already have sufficient authority to address this research area, noting that in FY 2008, "We expect $60.7 million will be specifically spent on researching the role of the environment in breast cancer development at NCI, and $35 million will be spent at the National Institute of Environmental Health Sciences, totaling almost $100 million in support of this important area across NIH."
Chairman Pallone noted that NIH had previously agreed to several revisions of the Senate version of the legislation (S.579). Dr. Winn reiterated that NIH did not oppose the Senate bill. S.579 was passed by the Senate Health, Education, Labor and Pensions Committee on February 27, 2008. Another witness, Fran Visco, president of the National Breast Cancer Coalition, said her group had negotiated with NIH on the revisions to the Senate bill. She and several House subcommittee members expressed hope that, with House concurrence to those revisions, the legislation may be passed during the current congressional session.
Dr. Electra Paskett
Marion N. Rowley Professor of Cancer Research, The Ohio State University
The eastern edge of Ohio is rimmed by a mountain range called the Appalachian Plateau, a densely wooded territory marked by rolling hills, streams, and stunning waterfalls. Most of the people who visit do so for the camping, fishing, hiking, or to tour historic landmarks that reflect the Native American and coal mining heritage.
Dr. Electra Paskett and her colleagues at Ohio State University (OSU) come here for a different reason. In this part of Appalachia, where the job market is depressed and poverty runs deep, the use of widely available cancer screening tests is low and, in turn, the cancer incidence and mortality rates are distinctly higher than in other parts of the state. "There's a problem here," she says. "We need to understand why and then do something about it."
The residents who live here are a world away - both economically and culturally - from where Dr. Paskett was raised. She grew up in Manhattan, where her late father, who was Greek, worked as a concert violinist and conductor. Nonetheless, in the course of her life and research, Dr. Paskett has developed a profound commitment to the welfare of people in Appalachia and other underserved areas of the country where circumstantial factors contribute to cancer health disparities.
"This is really important for the work that we do," says Dr. Mira Katz, a colleague at OSU. "She can take off her 'Dr. Paskett' hat and has the ability to talk one on one with people from different communities to find out the best way to connect with them. She's there to really help people, and that comes through all the time, despite differences in race or gender or any other demographic factor."
The connection may exist because for Dr. Paskett, this work is personal. Her first breast tumor was diagnosed in 1997 on a routine mammogram. Despite the fact that her mother and grandmother both suffered from the disease, she says, "The diagnosis still came as a shock." After surgery and radiation, she developed lymphedema in her hand and arm. Four years after the initial diagnosis, she had an axillary node recurrence. The second round of surgery and radiation, this time with chemotherapy, caused her to develop an enlarged, weakened heart, commonly called cardiomyopathy.
Her training as a cancer researcher (at the University of Utah and University of Washington in Seattle) brought only some comfort during the experience. "I knew that the treatments were good," she says, "but I also knew what could happen." She learned quickly that her familiarity with the health care system helped her identify who could answer her questions, "But this made me feel more empathetic for everyone else who is not a faculty member and doesn't have as much knowledge as I do."
Despite the long-term effects of her treatment - now mitigated by compression garments to limit the lymphedema swelling and medications to offset her heart damage - her friends and colleagues, including young investigators who she mentors, say that cancer has not kept Dr. Paskett down. In fact, they all remark on her energy and enthusiasm, which have led her to expand her research into lymphedema prevention and treatment, as well as quality of life for breast cancer survivors.
"Not many researchers span the cancer control continuum as she does," says Dr. Julia Rowland, director of NCI's Office of Cancer Survivorship. "Most people focus only on one aspect, such as treatment or prevention, but she has considerable breadth. This is one of the things that makes her such a strong researcher. She is a classic investigator who asks good questions and is open to new ideas. Integrative health, the interplay between mind, body, and environment on health, diversity and cultural competence…She just gets it."
Those who know her also admire her ability to accomplish so much while also finding time to enjoy her husband and three sons. She says that the secret is working smart. "You have to have a balance between your family, your work, and yourself - hobbies and other things that you like to do." As an example, she makes time for exercise almost every morning, and takes her husband, a physician assistant, along on trips if work requires her to leave during his birthday or other special occasions. If she is invited to a speaking engagement in New York City, she usually accepts because it gives her the opportunity to visit her oldest son, who is a college sophomore there.
Dr. Paskett says that one of the things she enjoys so much about living and working in Ohio is the diversity of surrounding populations. She also enjoys the direction that her research program is heading. "We're bringing biology in with behavior to look at the effects of lifestyle interventions on disease markers," she says. She's especially enthusiastic about ongoing research within the OSU Center for Population Health and Health Disparities, which is one of eight centers that work together as a network to explore the complexity of health disparities.
"We're looking at the issue of stress and how it relates to cancer, as well as other diseases," she explains. A research group in Chicago had done previous work showing that stress in animals can be induced by isolation, and that this in turn increases their tumor burden. This relationship in humans is now being examined across the eight centers.
"On the south side of Chicago, we saw big parallels with the animal models," she says. "In economically depressed, very urban neighborhoods, African American women didn't want to go outside of their houses. And here in Appalachia, we saw the very same things. We spoke with mainly rural white women, most of who had an abnormal Pap and were positive for HPV, and they said, 'I can't leave my house. We have no transportation, we have no jobs, we have no money to do anything.' So it's very interesting to see that underserved populations from different backgrounds and regions share the same problems. That deep down, they're more alike than they are different."
—Brittany Moya Del Pino
Selenium to Prevent Recurrence of Colorectal Polyps
Name of the Trial
Principal Investigator
Why This Trial Is Important
"That study was a major justification for doing a randomized controlled trial with a colorectal cancer-related endpoint," said Dr. Lance.
In this trial, patients who have a history of colorectal adenoma - noncancerous growths (polyps) found in the colon or rectum that can be precursors to colorectal cancer - will be randomly assigned to receive either daily selenium supplements or a placebo for 3 or 5 years. At the end of the supplementation period, patients will have a colonoscopy to check for adenoma recurrence.
Whether patients in the study are treated for 3 or 5 years is at the discretion of the treating physician; some patients at higher risk of adenoma recurrence need a surveillance colonoscopy at 3 years after adenoma removal, while lower risk patients will have a surveillance colonoscopy after 5 years.
The investigators plan to follow the patients for 5 years after the end of supplementation. In addition to seeing if patients taking selenium have a lower risk of adenoma recurrence and advanced adenomas (adenomas closer to becoming cancer), the trial will characterize any side effects observed with long-term, high-dose selenium supplementation.
For More Information
An archive of "Featured Clinical Trial" columns is available at http://www.cancer.gov/clinicaltrials/ft-all-featured-trials.
In Memoriam: Longtime NCI Employee Judy Patt
"Judy was an invaluable resource to everyone who ever made contact with her at NCI and would always try to find a helpful way of solving whatever problem was at hand," said her former supervisor Mary Anne Bright, associate director of the Office of Public Information and Resource Management, upon learning the news.
Ms. Patt came to NIH in 1962 as a Bacteriologist/Microbiologist and stayed until 1968, moving on to join a research company where she worked for nearly 20 years. In 1987, she returned to NCI and accepted a career appointment as a technical writer in the Office of Cancer Communications.
In 1999 she became a public affairs specialist in the Office of Cancer Information, Communications, and Education, and her last position, starting in 2002, was as a public health advisor for the Office of Communications Media and Public Communications in the Cancer Information Service Branch.
Ms. Patt received numerous awards for performance and special acts of service throughout her years of service, and she will be greatly missed by all of her co-workers, especially those in the Cancer Information Service Branch with whom she interacted on a daily basis.
Spring Research Festival Held at NCI-Frederick
In his keynote address, NCI Director Dr. John E. Niederhuber emphasized the uniqueness of the Frederick campus. NCI-Frederick is both a government-owned, contractor-operated facility and the nation's only Federally Funded Research and Development Center dedicated solely to biomedical research.
The annual research festival is open to the NIH and the Fort Detrick communities as well as the general public.
NCI Cancer Bulletin Writer Wins NAGC Award
A New Tobacco Threat?
Mr. Phillips' work was selected from several hundred submissions in that category.
NCI Partners with Canary Foundation on Prostate Cancer Study
NCI and the Canary Foundation, a nonprofit organization that funds research on early cancer detection, have announced a partnership for the purpose of identifying and validating biomarkers for high-risk prostate cancer.
Diagnosis and treatment of prostate cancer has its challenges, including overtreatment for non-lethal cases and the many cases of lethal prostate cancer that are still missed by current screening strategies. For example, the prostate-specific antigen (PSA) test commonly used to screen for prostate cancer is controversial, particularly its use in older men. One reason is that the forms of prostate cancer that are detected by PSA testing late in life often progress slowly, as opposed to the more aggressive and often fatal forms of the disease that may occur earlier.
NCI and the Canary Foundation signed a memorandum of understanding with a joint goal of reducing overtreatment by identifying aggressive versus passive prostate tumors. The Foundation - working with NCI's Early Detection Research Network (EDRN) - has pledged $3 million to initiate a Prostate Active Surveillance Study (PASS) at six research institutions across the country. EDRN will establish a disease-specific version of the Common Data Elements, a biospecimen management system, and a protocol oversight program to expedite the storage and processing of patient information and biological specimens.
Additionally, the Canary Foundation and EDRN will jointly establish a Biomarker Evaluation Group to determine those biomarkers that are most promising for evaluation, using the biologic materials collected by the Canary Prostate Consortium.
"Both Canary and EDRN believe that early detection technologies will lead the way on finding better cancer treatments for patients," said Don Listwin, founder and CEO of the Canary Foundation. "In this specific study, we hope to identify biomarkers that will tell us which prostate cancers need to be aggressively treated, and which do not. Being able to collaborate with EDRN will help us achieve this goal much faster."
Dr. Sudhir Srivastava, chief of NCI's Cancer Biomarkers Research Group, noted: "We are delighted to join forces with the Canary Foundation. With prostate cancer being one of the major focus areas for Canary's cancer programs, and with EDRN's multiple ongoing studies related to the early detection of prostate cancer, we see this as a complementary and significant partnership."
The six institutions that will participate in the active surveillance study are Stanford University; University of California, San Francisco; University of British Columbia; University of Washington; Fred Hutchinson Cancer Research Center in Seattle; and University of Texas Health Science Center at San Antonio.
The Canary prostate team is headed by Dr. Peter Nelson, member of the Human Biology and Clinical Research Divisions at Fred Hutchinson and professor of oncology at the University of Washington. He is also a practicing medical oncologist, with a clinical specialty focused on the treatment of prostate cancer.
"We are proud to launch this new study with EDRN and with the participation of leading research institutes," said Dr. Nelson. "Through collaboration we can make bigger strides in providing better, more individualized treatment for prostate cancer patients."
—Bill Robinson


text:
Next, you'll be asked to connect with Twitter. Rest assured, we will never send a tweet from your account
without your permission.
We will send you an email with an invite soon.
Impressed everyday with my @cycle4survival team. Amazing cause to fight rare cancers and such a fun,…
Follow @LvM on Twitter

subset: commoncrawl


text:
ALBANY, N.Y. (AP) - Attorney General Eric Schneiderman is issuing a warning that scam artists posing as Microsoft representatives are targeting New Yorkers for credit card information.
The thieves contact people by phone and try to talk them into giving remote access to their computers, claiming that they have a virus. Victims are then asked for credit card, bank or PayPal account information.
On Tuesday Schneiderman's office said victims who allow the remote access but don't comply with payment demands have their computer disabled and files deleted. According to the press release the scammers usually speak with a foreign accent and appear to be working overseas.
The thieves may change the name that appears on Caller ID to say "Windows Support." They are also posing as organizations affiliated with Microsoft, such as P.C. Solutions.
Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Didn't find what you were looking for?
All content © Copyright 2000 - 2014 Fox Television Stations, Inc. and Worldnow. All Rights Reserved.
Privacy Policy | New Terms of Service What's new | Ad Choices


text:
Search Results
Doctors 1 - 2 of 2
Alla Skalnyi, M.D.1720 El Camino Real
Suite 145
Burlingame, CA 94010
(650) 239-9340
Specializing inObstetrics and Gynecology
Accepting new patients
Offers My Health Online This provider offers Sutter Health's electronic health record with the following online services: Email your doctor's office, Prescription refills, View test results, Proxy access for caregivers, Track immunizations, Secure mobile access, Schedule an appointment*, Pay bills online*. * Services with an asterisk vary by doctor.
Alla Sragets, M.D.101 So. San Mateo Dr #112
San Mateo, CA 94401
(650) 344-7799
Specializing inObstetrics and Gynecology
Accepting new patients
Doctors 1 - 2 of 2
Want to See More Options?Need to see more options? You can remove your filters to show all Obstetrics and Gynecology Doctors .
Remove filters and show more options


text:
A man has been charged in a child's death after the 4-year-old fatally shot himself in the head over the weekend.
Joshua Michael Greenhill owns the gun the boy used. He was charged with careless discharge of a weapon in Monroe County District Court Monday afternoon. The charge is a misdemeanor, which carries a 30-day jail sentence and a $2,000 fine.
Greenhill was released on his own recognizance.
Copyright 2013 Toledo News Now. All rights reserved.


text:
Deftones are pleased to announce that Glassjaw will be supporting them at
their upcoming show at the Greek Theatre in Los Angeles CA on Nov 1. Pick
up you tickets HERE if you haven't already.
Check out the official music video for Deftones' "Romantic Dreams," which premiered today on Red Bull.
Tickets to Deftones' show at the Greek Theatre on November 1st, are now on-sale HERE.
Tickets to the upcoming Hail to the King Tour with Avenged Sevenfold and Deftones are now on sale for the below dates. Click HERE for details on where to purchase tickets.
10/18 Houston, TX
10/19 Dallas, TX
10/20 San Antonio, TX
10/23 Oklahoma City, OK
Deftones are pleased to announce they will be headlining the Greek Theatre in Los Angeles on November 1st. Ticket pre-sales begin August 7, and general on sale begins August 10 at 10am PDT. Check back for details on where to purchase tickets.
Tickets to Deftones' upcoming Hail to the King Tour with Avenged Sevenfold are now on sale for the below dates. Click HERE to purchase tickets.
Additionally, a show has been added at the Verizon Wireless Amphitheatre in St. Louis, MO on 10/11. This date will go on sale August 10. Tickets for Texas and Oklahoma dates go on sale August 9.
10/3 Chicago, IL
10/5 Indianapolis, IN
10/6 Cincinnati, OH
10/8 Baltimore, MD
10/9 Boston, MA
10/12 Bloomington, IL
10/13 Detroit, MI
10/15 Atlanta, GA
10/16 Orlando, FL
10/23 Oklahoma City, OK
10/26 Las Vegas, NV
Venue and on-sale information is now available for Avenged Sevenfold's "Hail to the King" tour with Deftones and Ghost B.C. All dates go on sale August 2nd at 10am, except all three Texas shows will go on-sale August 9th at 10am. Full details below:
10/3 Chicago, IL - Allstate Arena
10/5 Indianapolis, IN - Klipsch Music Center
10/6 Cincinnati, OH - US Bank Arena
10/8 Baltimore, MD - 1st Mariner Arena
10/9 Boston, MA - TD Garden
10/12 Bloomington, IL - US Cellular Coliseum
10/13 Detroit, MI – Joe Louis Arena
10/15 Atlanta, GA – Phillips Arena
10/16 Orlando, FL – Away Center
10/18 Houston, TX – Cynthia Woods Mitchell Pavilion
10/19 Dallas, TX – American Airlines Center
10/20 San Antonio, TX – AT&T Center
10/22 Omaha, NE – CenturyLink Center
10/23 Oklahoma City, OK – Chesapeake Energy Arena
10/26 Las Vegas, NV – Mandalay Bay Events Center


text:
One driver was sent to the hospital Tuesday night after losing control of his car, and driving into a house.
It happened just after 7PM in the 2100 block of Pine Tree Road in Longview.
Police say that the driver lost control of his SUV, went off the road, hit an electrical pole, then hit the side of a house.
The pole fell across Pine Tree Road, hitting another truck that was driving nearby. The driver of the truck was not hurt.
One person in the home at the time of the accident was not hurt, but said he thought the crash was loud thunder when it happened.
The driver of the SUV will also be ticketed for driving at an unsafe speed.
When the electrical pole that was struck fell across the road, the connecting wires also pulled down the top of a second pole on the other side of the street.
Police tell KLTV 7 that the neighborhood traffic flow will be disrupted for most of the night while power crews work on the damaged pole.
Stay tuned to KLTV 7 for further updates.
Copyright 2013 KLTV. All Rights reserved.
1960 Union Ave.
Memphis, TN 38104
(901) 726-0555
FCC Public File
EEO Report
Closed Captioning


text:
You are visiting our UK site. Click here to view our US site
Arirang Mild Moxa (DB203)
Easy to stick on Traditional Korean moxa.
Rolled moxa cynlider wth a sticky base.
Each box contains 200 stick on moxa.
Weight (including packaging): 300g
Tax is not applicable to those living outside the European Economic Community. For more info click here.
99 in stock
Now: £7.95 (£9.54 inc. tax)
Customer Reviews
There are currently no reviews for this product. Be the first!Review this product...
People who purchased this also purchased...
Female Acupuncture Model - SmallSoft white vinyl with 360 points and 14 meridians
Price: £14.95
[more info]
Moxa ExtinguisherChrome plated moxa extinguisher
Price: £2.95
[more info]
Hoist Smokeless Moxa SticksThis densely packed moxa stick generates intense h...
Price: £3.85
[more info]
Gua Sha Oil - ClearProfessional oil for gua sha treatment and massage
Price: £6.95
[more info]
ASP Original Classic 80Semi-permanent ASP Original needles shaped like a ...
Price: £20.95
[more info]
Chosei-Kyu Stop Smoke MoxaVery mimimal smoke emission with no odour
Price: £12.95
[more info]
Dongbang Incense Sticks - Smokeless Non-scentedSmokeless non-scented Korean incense sticks
Price: £6.50
[more info]
Moxa Extinguisher with PlateMoxa extinguisher mounted in the middle of a plate
Price: £5.00
[more info]
Gua Sha Jade - Cosmetic Roller - Two RollersGua sha jade cosmetic roller with two rollers
Price: £9.95
[more info]
Subscribe To CMT
Shopping Basket
Your basket is empty!
Change Language
Change Currency
Events Calendar
Korean Hand Therapy with Jong Baik in London 04/09/2014-09/09/2014
Korean Hand Therapy (KHT) is unique when compared to other hand reflexology... [more]
Master Tung Acupuncture Parts 1&2 with Philip Weeks - Novemeber 7th/8th
A very practical 2 day workshop with lots of practise!. Tung Acupuncture is well known for its quick and spontaneous results... [more]


text:
Last week, MassBike instructor extraordinaire Laura Smeaton led a workshop on "Biking in the City" for under-served immigrant populations in the City of Cambridge. Over 40 adults and 25 children learned more about riding comfortably in their own neighborhoods by asking questions and discussing topics such as overcoming common barriers to bicycling. The great turnout was a result […]
Tag Archives | City Bicycling
Sign up for our email newsletter
- Will Beer for Bike September 5, 2014
- Biking in Melrose: Good for Business September 5, 2014
- Executive Director David Watson Shifts Gears September 4, 2014
- Foxx Announces New Initiative at Pro Walk/Pro Bike September 10, 2014
- The Different Safe Routes to School September 18, 2014
- West Station Is Approaching September 30, 2014
- The Different Safe Routes to School September 18, 2014
- Action Alert: Help Create a People's Pike September 15, 2014
- Foxx Announces New Initiative at Pro Walk/Pro Bike September 10, 2014
- Will Beer for Bike September 5, 2014
- John Z Wetmore: Here is a video of the remarks by U.S. DOT Secreta...
- brodio: You can sign up for our newsletter on the home pag...
- labicicletaestatica: I'll immediately grab your rss as I can't find y...
- NoBo Magazine | MassBike: Biking in Melrose is Good for Business: […] – Melrose became the latest commun...
- Ron Farnsworth: Good stuff, Gotta have my Training Wheels.. Than...
Action Alert Advocacy and I ride Ask MassBike bay state bike week beer bicycle bike/walk summit bikeability assessment bikeable communities program bike lanes bike night bike parking bike safety bike valet boston charity ride complete streets Congress construction DCR donate Education fun Funding fundraiser infrastructure law Legislation legislature Longfellow bridge MassBike massdot mass in motion MBTA National Bike Summit Pioneer Valley ride Safe Routes To School safety Summer Century Volunteer Volunteering vulnerable road users walkboston


text:
Rick Rack
This dress was made with Fat Quarters from the Make Life Collection by Sweetwater
1 Pillowcase dress
Aubrey Schwartz
This dress was made with Fat Quarters from the Make Life Collection by Sweetwater
Ohh! I've been wanting to do those for my girls :) can't wait to try it out
what a great blog! I`m so happy I found it! Here is so many inspirations and I love it! <3
Have a nice time,
A nossa alegria supera nossa tristeza, nosso consolo supera nossa dor, nossa fé supera nossa dúvida, nossa esperança supera nosso desespero, nosso entusiasmo supera nosso desânimo, nosso sucesso supera nosso fracasso, nossa coragem supera nosso medo, nossa força supera nossa fraqueza, nossa perseverança supera nossa inconstância, nossa paz supera nossa guerra, nossa luz supera nossa escuridão, nossa voz supera nosso silêncio, nossa paciência supera nossa impaciência, nosso descanso supera nosso cansaço, nosso conhecimento supera nossa ignorância, nossa sabedoria supera nossa tolice, nossa vitória supera nossa derrota, nossa ação supera nosso tédio, nosso ganho supera nossa perda, nossa resistência supera nossa fragilidade, nosso sorriso supera nosso choro, nossa gratidão supera nossa ingradidão, nossa riqueza supera nossa pobreza, nosso sonho supera nossa realidade... Nosso amor a Deus, ao próximo, à vida, nos faz superar tudo! (Pr. Edilson Ram)Uma semana de vitórias Deus é com tigo creia! TENHO UM BLOG GOSTARIA DE TI CONVIDAR SEGUIR O ENDEREÇO É:http://SNSDEUS.BLOGSPOTFICA COM NOSSO PAPAI já estou te seguindo te encontrei através de uma amiga,post teu comentario vai ser uma benção prs seguidores e visitantes uma semana com muita sorte de benção!!!
These look cute and easy! Thanks for sharing!
So cute! I have a toddler and an older girl, so this afternoon we're going to make one dress and one shirt. Thanks for the tute!
What a simple and fun idea. I am not much of a seamstress so the less I have to sew the better. Thanks for sharing your project with us.
Dress A Girl Around the World is a charity that accepts this "dress" donation. It is a fabulous organization.
Sometimes this is called a Pillowcase Dress.
Whatever you call it and however you make it, there are needy girls around the world that need modest dresses.
So cute, I can't believe I haven't tried making these before.
OMG I want to this for my granddaughter and for dress a girl around the world. Come on let's do this!!!
Oh this is just the thing I was looking for!! My daughter is going to a birthday party and I have just the perfect fabric for this!!! :D Thanks for the tutorial :)!
I love this, and have an almost 2 year old granddaughter and several other little girls in the family. Guess what they will be getting for presents soon! Thanks for this great pattern. I love it.
this would have to be the best PC dress tutorial I have seen and there are plenty of them out there!!!
Very cute! I have 3 daughters and will be making each of them one for the summer!
I just put this together in less than and hour and it's adorable!
Very Cute,just made one out of some small yardage that my granddaughter (4) picked from my "stash". Combined 2 ribbons with a decorative stitch, and will do an applique to cover a spot on the fabric. I know she'll love it. thanks for the cute idea, and for helping reduce my "fabric store",
Great pattern! Thanks, I made it in literally minutes
Thanks for the quick and easy pattern. I enjoyed making the dresses!
This was so simple and easy... thanks for a wonderful tutorial!


text:
They have as many offensive rebounds as we do defensive, that's a big problem.
They have as many offensive rebounds as we do defensive, that's a big problem.
Love the quiet confidence of T Ross. I believe he's gonna turn out pretty darn good.
Keep Calm & Chive On
kleiza and his butterfingers
Casey is not impressed, someone is getting a benching
was just about to call Pietrus a chucker, but then he made that great block! I'll refrain from calling him a chucker for now.
Keep Calm & Chive On
easy bucket time, jose is in
someone not happy about sending pietrus to the line
come on sportsnet i want to see that again
We're shooting 59% and it's tied, come on.
Kleiza needs to go... got no use for him. Would've liked to see Landry for a few mins there, but I guess he's not really ready yet.
Keep Calm & Chive On
Guards need to come in and help out on the board.
Whoever is guarding singler is doing an awful job of boxing out.
"Championships are what we live for, now lets go win them."Tim Leiweke
Basketball has clear winners every night --except at the draft, which is all homework, politics and chance.
There are currently 1 users browsing this thread. (0 members and 1 guests)


text:
Best Ranges
Of 20 models tested, these six are our very best bets.
By The Good Housekeeping Research Institute
Back Next
Courtesy of Whirlpool
Value Buy (Gas)
Whirlpool Gas Range with Convection WFG720H0AS ($1,349, amazon.com)
Lots to love: warming drawer, center burner; converts temps to convection equivalent. One con: no traditional self-cleaning.


text:
the same zit-zapping mask used in our spas
Boost your blemish-battling regimen with this straight-from-our-spa facial treatment, a weekly must for pimple-prone skin. The unique rubber texture is designed to envelop skin's surface to absorb impurities and allow the mask's key ingredients to be optimally absorbed by the skin. Plus, it's packed with pore-de-clogging, oil-absorbing, super-soothing extracts and nourishing, detoxifying seaweed. So if you're looking for a clean, clear, shine-free complexion—'mask', and you shall receive! Includes 6 individually wrapped mix-it-yourself masks, 6 spatulas and measuring scoop.
• With seaweed, tea tree, willow and menthol extracts
• Purges pores, absorbs impurities and calms skin
• Helps control oil, fade blemishes and prevent future breakouts
out of stock
about bliss
Bliss was born in 1996 with a single spa in New York City, and ignited a spa revolution by combining super-effective services with a fun, ''no-attitude'' atmosphere. Our bliss spa treatments became so sought-after that we translated them to a line of bliss products for bath and body and bliss skin care products, so our grooming groupies could spa-at-home and achieve ''domestic Bliss''. These beloved bath, body and skin care blends are all inspired by countless hours of tension-nixing and skin-fixing at bliss spas world wide, so each one receives the ''esthetician seal of approval''—and a dose of ''tongue-in-chic'' humor, of course.
www.blissworld.com is your one-stop-shop for spa products, skin care products, bath and body products, hair removal and body waxing, shapewear, style, fitness footwear, makeup, hair care and the best gifts for her. We search the world over to bring you what we've found to be the finest cleansers, toners, exfoliators, moisturizers, anti aging treatments, masks, sun protection, pro tools, soaps, gels, body scrubs, supplements, cellulite creams, and cosmetics.
customer service
888 243 8825
shop at blissworld
and earn points+perks
our top brands


text:
Recent Posts on the HSPI Blog
Understanding morale at DHS: The missing details
Posted on Tuesday September 30, 2014
NTAS under scrutiny: No terrorism advisory system?
Posted on Monday September 29, 2014
Lloyd's of London releases data on the cyber insurance market
Posted on Monday September 29, 2014
Event this afternoon: "Cybersecurity for Government Contractors"
Posted on Monday September 29, 2014
Assessing the U.S. Secret Service's budget situation
Posted on Monday September 29, 2014
HSPI in the News
Estonian President on Cybersecurity
Founded in 2003, the George Washington University Homeland Security Policy Institute (HSPI) is a nonpartisan "think and do" tank whose mission is to build bridges between theory and practice to advance homeland security through an interdisciplinary approach. By convening domestic and international policymakers and practitioners at all levels of government, the private and non-profit sectors, and academia, HSPI creates innovative strategies and solutions to current and future threats to the nation.
Featured Experts
Bert Tussing
Ronald Marks
Michael Downing
Bert Tussing
Director, Homeland Defense and Security Issues, Center for Strategic Leadership, Army War College
Lieutenant Colonel (Ret.), U.S. Marine Corps
Ronald Marks
President and Senior Partner, Intelligence Enterprises
Director, Cyber Doctrine Program, Battelle
Michael Downing
Deputy Chief and Commanding Officer, Counterterrorism and Criminal Intelligence Bureau, Los Angeles Police Department
HSPI Issue Brief Series
Economic Espionage and Trade Secret Theft: An Overview of the Legal Landscape and Policy Responses (PDF)
Concern about cyberespionage and intellectual property (IP) theft, particularly trade secrets, has intensified—and with good reason. While these threats are not new, rapid technological advances resulting in greater connectivity and data storage and more globalized supply chains have increased the opportunity—and potentially the payoff—to breach corporate networks and acquire sensitive corporate data.
Northern Mali: Armed Groups, State Failure, and Terrorism (PDF)
One year ago an uneasy alliance of armed groups, including jihadists with ties to al-Qaeda, seized control of northern Mali, a landlocked region slightly larger than the state of Texas.
Transportation and Supply Chain Security: Systemic Changes and Policy Opportunities (PDF)
In the past several decades these global networks of transportation and trade have become increasingly integrated and interdependent, decreasing the costs and accelerating the speed of the movement of people and goods. However, this integration and complex interdependency has led to new risks to the system, making it more vulnerable to disruption.


text:
The DeKalb County commissioners are expected to meet on Tuesday after investigators searched DeKalb County CEO Burrell Ellis' home and his downtown office in Decatur on Monday.
Executing seven search warrants, authorities confiscated computers and boxes of evidence as the CEO was appearing before a special grand jury involving the watershed management department and its contracts.
Ellis appeared at the DeKalb County courthouse on Monday. He said he was subpoenaed, and spoke to a grand jury for about an hour.
The grand jury was convened by DeKalb District Attorney Robert James back in January of 2012 to look into the possible improprieties in the water and sewer departments. James said earlier this year he wanted to find out if individuals were manipulating the bidding process.
Ellis says all his relations with vendors have been above board.
"As the CEO of the county, I talk to vendors who do business with the county. Some of whom are watershed management, but no inappropriate contact with any vendors," said Ellis.
Ellis told FOX 5 that the questioning was routine, and that he testified before the special grand jury in the past.
"We were here to talk to the grand jury about watershed management and the procurement process in DeKalb County. We've been here before. We've answered all of the questions truthfully and honestly and straightforward. And I've always directed my folks to cooperate with the grand jury, and make sure that they get all of the answers that they need," said Ellis.
As Ellis answered questions before the grand jury, investigators carried out seven search warrants, including a search at the CEO's West Ponce de Leon office and his home on Monday afternoon. FOX 5's Chris Shaw reports investigators left Ellis' home at around 1 p.m., carrying with them four boxes and a computer.
Search warrants obtained by FOX 5 News indicate investigators were looking for handwriting samples as well as personal and business financial records, including checking, savings, retirement and investment accounts.
Investigators want the CEO's tax returns, campaign records, computer hard drives and all consulting agreements with vendors doing business with DeKalb among other things.
One vendor, Rural/Metro, released a statement saying, "Rural/Metro has proudly served the emergency ambulance needs of DeKalb County citizens since 2010. In light of the ongoing nature of this investigation, the company can provide no comment at this time."
Ellis said he was surprised by the raid.
"I don't know that I'm a target. I do know that they want to look at some documentation," Ellis said. "It's a pretty broad warrant that they've issued. But again, I would have provided it."
The CEO said that he is "perplexed" by the investigation but wants voters to know that he will cooperate fully.
"I am going to continue to be honest. I'm going to continue to be transparent. I'm going to continue to work with all the officials involved in this process," said Ellis.
The warrants indicate investigators are looking for evidence of a number of criminal charges, such as racketeering, extortion, bribery, bid rigging, and theft concerning programs receiving federal funds.
One search warrant was for the CEO's American Express credit card account, thumb drives, cell phones and all email messages to a number of people including DeKalb's outgoing chief operating officer Richard Stoger. When reached by FOX 5, Stoger had no comment.
Ellis' 83-year-old mother was the only person at the CEO's home when it was searched. Late in the afternoon, a man picked her up and drove away.
Ellis is expected to run the DeKalb County Commission meeting when it meets on Tuesday at 10 a.m.
35 Skyline Drive
Phone: (407) 644-3535
Didn't find what you were looking for?
All content © Copyright 2000 - 2014 Fox Television Stations, Inc. and Worldnow. All Rights Reserved.
Privacy Policy | New Terms of Service What's new | Ad Choices


text:
Drop Shipping from Amazon to eBay Buyers Instructions:
What if I told you that drop shipping products from Amazon to Ebay could put thousands of dollars in profit per month in your pocket? – You don't have to pack anything, you don't have to keep any items in stock, and there is little to no work involved, I ask would you do it?
To Drop ship from Azon to eBay in a Plain Brown Box visit: Plain Box Drop Shipping, and click on the boxes each time… Continue reading
There is a huge seller suspension problem with eBay's Guardrail System
Good sellers like this one are being suspended left and right. There is no appeal process. Customer service reps just say you don't meet the qualifications to sell on eBay.
This topic is being discussed on many blogs, forums, and Facebook groups. What it all boils down to is this. eBay want's to automate everything so they can lay off as many employees as possible. They came up with this Guardrail System that scans their databases and if it… Continue reading
Has your eBay sellers account been suspended? This information might help.
Here is a list of eBay Employee email addresses that might be able to help get your suspension lifted.
We all know how hard it is to make contact with someone at eBay support because of how they hide contact info.
Apparently someone at eBay Community (Lithium Technologies) left the barn door wide open allowing Google to index 181 current eBay employee email addresses.
There is a good chance these addresses will be wiped from Google's index as soon… Continue reading
eBay Motors is one of the oldest eBay forums.
But a few days ago another poster that is well known on several other eBay forums posted this message.
Is eBay motors board needed? 01-04-2014:
"Seems to be only 5 regulars and not much advice. The knuckle walkers and the 19 year old programmers could any day now just say "Lets just turn it off"
It's sad because this board used to have some of the best brains in the car business hanging out on it. There was never a… Continue reading
Came across this job listing on Elance. Notice this verbiage: Also, sending people to eBay or Amazon's customer service is unacceptable.
We are looking for an eBay and Amazon expert to go on their respective forums and help our potential customers solve problems they are having with each platform. We expect you to gather information for us, which will help make our product even better.
If you are someone who spends their time doing this already, then please reply now. Below, you will find some sample questions. Please… Continue reading
Here is another seller that claims he got no warning that his eBay selling privileges were about to be permanently suspended.
In this webcast interview John from Windy City Authentics (WindyCityAuthentic eBay ID) tells me he got no warning he was about to get the bums rush from his eBay selling slot. But the canned response email he received said he would still be able to buy. He says there is no appeal process, and support reps will not tell him the reason he was given a permanent… Continue reading
Man stole brains from dead mental patients and sold them on eBay
Only on eBay! Ya cant make stuff like this up!
Desperate for cash, a young man breaks into a warehouse to steal the brains of dead mental patients, and the body parts are later sold on eBay.
Authorities say David Charles, a 21-year-old Indianapolis resident, is accused of breaking into the Indiana Medical History Museum multiple times last year and stealing jars of human brain tissue and other preserved material. A tipster who paid hundreds of dollars on… Continue reading
eBay issued a press release claiming PayPal was safe after Target recently suffered a huge data breach.
HOWEVER this security advisory published by ThreatPost.com exposed an XSRF Vulnerbility eBay claims they fixed.
eBay is vulnerable to a hack that would allow an attacker to hijack an account and make unauthorized purchases from the victim's account that would be difficult to disprove.
The vulnerability was discovered and reported to eBay in August, and despite three separate communications from the online auction and marketplace that the code in question was repaired, the… Continue reading


text:
Dorcheat-Bistineau Chapter of the Daughters of the American Revolution recently held its annual essay contest. Fifty-five area students from grades 5-8 participated. The assigned topic of the essay was "forgotten Patriots Who Supported the American Struggle for Independence."
Winners of the 2012 DAR Essay Contest were honored at the January DAR meeting held at St. John's Episcopal Church Youth Building. Members enjoyed hearing the students read their outstanding essays.


text:
Open House offers sitting meditation, followed most Monday evenings by tea and an introductory talk related to meditation.. Suitable for those who are new to meditation, as well as all others.
We are at our new location: 2825 Meridian Street, Suite 201, near Illinois.
Monday night Open House schedule:
7-7:45pm - Sitting/Walking Meditation and Free Meditation Instruction (just show up -- someone will meet you to offer instruction)
7:45-8 - Announcements and Tea Break
8-8:40pm - Introductory Talk (suggested donation: $5)
All welcome!
Never let cost be an obstacle to participating in any Bellingham Shambhala activity. Please pay what you can, and feel free to ask about work-study for any event or class.
Shambhala Online Teleclasses
Intro Meditation Programs
Find a Meditation Centre
Quick View of Programs by Center


text:
Dead Space Extraction Sales Slow, Analyst Points to Poor MarketingSales of Visceral Games' Dead Space Extraction--the Wii rail shooter adaptation of the original Dead Space--have been unimpressive following its September 29 release, leading one analyst to blame a lackluster EA marketing campaign.
The game sold only 9,000 copies in the US between September 29 and October 3, according to NPD sales data.Edge.
"The success or failure of a Wii title usually correlates directly to marketing spend," he added. "If Electronic Arts spent little on marketing, I am sure the sell through was no surprise to them. So I do not believe sell through was a disappointment to EA."
You must be logged in to post.


text:
Shop Our Store
More Ways To Shop
More Ways To Save
Select your preferred location and we'll note which parts are ready to be picked up TODAY.
Shock, Avenger, Monotube, Circle Track, Rear, 24.500 in./15.500 in. Length, 10/2 Compression, Rebound Valving
This part is normally shipped directly from the manufacturer / Supplier.
Order this item and get free delivery and handling on your entire order! Offer excludes truck freight fees. Valid on orders shipped in the contiguous United States.
Estimated Ship Date: 10/27/2014 (if ordered today) Would you rather pick it up? Select Location
View Similar Products
Integra steel Avenger monotube shocks are suspension control for champions! Their Avenger steel shocks have shafts machined from hard, chrome plated, high-strength stainless steel with Integra aircraft-grade billet aluminum pistons for repeatability, strength, and durability. A floating piston separates the nitrogen from the fluid to eliminate foaming effects on the damping force. The shocks include a snap ring groove for coil-over applications and are available in Schrader valve or non-Schrader valve configurations to meet the regulations of your sanctioning body. Integra technology, an economical monotube design, and consistent winning performance are what Integra steel Avenger monotube shocks are all about. Why put anything else on your race car?
Some parts are not legal for sale or use in California on any pollution-controlled motor vehiclesBack To Results


text:
A stormy sea crossing when fleeing from Riga to London is supposed to have inspired Richard Wagner to set the saga of the Flying Dutchman to music, which he had shortly before read in Heine's »Memoirs of Herr Schnabelewopski«. In so doing he was bowing to the contemporary taste for operas with a supernatural theme.
The Dutchman is cursed to roam the seas with his crew for the rest of eternity; a fate from which only a woman's true love has the power to release him. Every seven years he is permitted to seek out his female saviour on land. Senta, whom he wishes to marry, feels it her destiny to save him. However, when the Dutchman learns of another younger rival for her hand, he has misgivings about Senta's fidelity and turns his back on her. The young woman, broken-hearted, swears her undying love before casting herself into the sea; and when the Dutchman, together with his ship, accompanies her into the watery depths, the curse is finally broken.
With its focus on Senta's inner life, and her act of selfless redemption, the »Flying Dutchman« occupies a unique place in Wagner's operatic oeuvre. The work was premiered in Dresden's Court Theatre in 1843.
Romantic opera in three acts by Richard Wagner
Running time 2 hours 15 minutes
Premiere 15 Jun 2013
Musical Director: Constantin Trinks
Staging: Florentine Klepper
Set Design: Martina Segna
Costume Design: Anna Sofie Tuma
Lighting Design: Bernd Purkrabek
Video: Bastian Trieb
Choir: Wolfram Tetzner
Dramaturgy: Sophie Becker
Holländer: Markus Marquardt
Senta: Marjorie Owens
Daland: N.N.
Mary: Christa Mayer
Erik: N.N.
Steuermann: Simeon Esper
Saxon State Opera Choir Dresden
Choir of the Theodore Gouvy Gesellschaft
Staatskapelle Dresden
With generous support of the foundation of the Semperoper Dresden


text:
Surprise! Good Old Games Is Not Dead, Relaunches TomorrowBy Xav de Matos, Sep 22, 2010 9:45am PDT In a conference online moments ago, representatives of Good Old Games confirmed that its suspected marketing ploy of closing down was just that, a marketing ploy.
Two representatives dressed as monks and referring to GOG as a "brother monk" outlined that the website will relaunch with a new look, replacing "98% of the site's original code."
The website will continue to operate in many ways as it has in the past: Games will still be DRM-free, titles will continue to be sold separately, and GOG will not run off a separate client.
During the conference, disguised as a sermon, the "monks" discussed their disappointment that many people believed the website was shut down. With a line in the original announcement like, "We're closing down the service and putting this era behind us as new challenges await," it's unclear how anyone got that idea.
The pair of "monks" ended the conference by confirming all existing titles will remain and the service will add Baldur's Gate: The Original Saga (including the expansion Tales of the Sword Coast) for $9.99, when the service relaunches tomorrow at 8a.m. EST.
Other hot new features include community-made "GoGMixes" allowing players to create a listing of themed titles to share with GoG users, better searching, forums, a recommendation engine, and a "like" button! So, worth the confusion, fellas!
Middle-Earth: Shadow of Mordor season pass highlighted in new trailer
- 75
Shacknews Chatty Community's Top 100 PC Games of All-Time: #10-1
- 68
Middle-Earth: Shadow of Mordor review: simply walk into Mordor
- 51
- 43
Super Smash Bros. Wii U game and controller bundle spotted on Amazon
- 22
- 22
By: geedeck x Show Full PostJerks >:(Sep 24, 2010 12:59pm PDTJerks >:( : geedeck
By: deathofrats x Show Full PostI was on the fence about GoG before this, but this has pretty much sealed the deal that I won't buy from them.Sep 22, 2010 10:08am PDTI was on the fence about GoG before this, but this has pretty much sealed the deal that I won't buy from ... : deathofrats
Thread Truncated. Click to see all 14 replies.
OK.. Like they care... : PinkyImp
You seem to care. : razoric
I'll give it a second thought when they fire their PR manager/department that made up this bullshit campa... : Lukiopimp
GoG have a great website, a great service and a great amount of great games. If you were on the fence ... : Mystery0000
this is a great post : DewFuel
By: Evil Bones x Show Full PostThey should've just changed their page to a video of Never Gonna Give You Up by Rick Astley. It would've worked out much better.Sep 23, 2010 8:09am PDT
By: vx2o x Show Full Posti told uSep 23, 2010 2:39am PDTi told u : vx2o
By: Inarion x Show Full PostThey need to fire their marketing director (if they have one).Sep 22, 2010 9:47am PDT
Thread Truncated. Click to see all 13 replies.
MY VIDEO GAMES!!!!!!!! Their facebook page is pretty hilarious right now with all of the outrage people f... : Ohvee
The thought of not being able to buy Independence War kinda bummed me out. Glad they're coming back. T... : aggro crag
Do something big like...shut down your service unannounced, under the pretense of going out of business, ... : Happy Doodle Muffin
Right from the beginning they said "you will be able to download the games you bought". : Ohvee
Well, I wouldn't do the same thing. Maybe I just don't understand Polish comedy? : aggro crag
You mean give him a raise for a job well done. : Mystery0000
By: Unkei x Show Full Postoh snap!Sep 22, 2010 11:57pm PDToh snap! : Unkei
By: PinkyImp x Show Full PostBaldur's Gate is official. Will be available tomorrow for 10 bucks if anyone interested.
Sep 22, 2010 11:42pm PDT
By: Mystery0000 x Show Full PostLike I've been saying all along, this is awesome marketing.
All of you that can't handle a bit of humour, cry me a river. This was fantastic.Sep 22, 2010 10:32am PDTLike I've been saying all along, this is awesome marketing. All of you that can't handle a bit of humo... : Mystery0000
By: techx4 x Show Full PostI can understand both sides of the issue. But in the end I think people/gamers take things WAY too seriously and whine WAY too much. I mean fine, give them some shit about the dumb stunt, but all the pissing and moaning about it is just overreacting, get over it.Sep 22, 2010 10:03am PDTI can understand both sides of the issue. But in the end I think people/gamers take things WAY too seriou... : techx4
Thread Truncated. Click to see all 12 replies.
What, the firestorm over Dante's new look wasn't enough to convince the sane among us that gamers can be ... : TwitchCannon
I mean, fine - take away access to download titles they've legally purchased for a half-week as as a 'dum... : NickDelios
By: Derringer x Show Full PostThis will be just like the Modern Warfare 2 outrage that caused everyone to boycott it. Oh waitm they still bought it anyways.Sep 22, 2010 10:28am PDTThis will be just like the Modern Warfare 2 outrage that caused everyone to boycott it. Oh waitm they sti... : Derringer
Thread Truncated. Click to see all 14 replies.
If they throw In some great classic PC games. I can guarantee almost everyone will come back. Gamers t... : PinkyImp
Pretty much, I do understand that people were locked out of their purchases for a few days and that was p... : Derringer
GOG pulled a stupid move, and their poorly-worded "goodbye" announcement sent the wrong message. "Cannot ... : Orange Pylon
No, the people who boycotted it did not buy it. People who said they wouldn't buy it did, but they did... : Ebu
By: Tech T x Show Full PostI like their service and own a couple games purchased from them, but fucking with people's trust with a stunt like this is not cool.Sep 22, 2010 2:26pm PDTI like their service and own a couple games purchased from them, but fucking with people's trust with a s... : Tech T
By: citizenswift x Show Full PostI think that whether you thought it was funny or not is dependent on your perception of GOG in the first place. If you cared deeply about what they were doing and perceived them as the earnest underdogs, fighting against money-hungry publishers demanding DRM, then you likely feel that you've been taken advantage of.
I bought a few more games from them than I normally would, purely to show support for what they were doing. Now I feel betrayed, I don't feel like helping any more.Sep 22, 2010 3:41pm PDT
By: watcherxp x Show Full PostI no longer trust these assclownsSep 22, 2010 10:32am PDTI no longer trust these assclowns : watcherxp
By: CheeZySpr1nklz x Show Full Postto the GOG shutdown and restart: YAWN.
BG will be a good addition. it would be nice to see the D&D SSI gold box games on GOG too... or were they already there? or anything SSI.Sep 22, 2010 2:21pm PDT
By: Visceral Monkey x Show Full PostAssholes. Stupid, stupid, stupid.
Now, about getting BG tomorrow...Sep 22, 2010 10:46am PDT
By: qtussin x Show Full PostLooking ahead, I wonder what will be their greatest success in terms of the publishers and games they can get on GOG. I know they've done a poll on their site in the past. To me, there's not much left.
EA -- I care mostly about the Origin games but understand that EA has the rights to a lot of the great titles
Black Isle -- looks like these games are on the way
LucasArts -- to me, this one is the jackpotSep 22, 2010 11:40am PDTLooking ahead, I wonder what will be their greatest success in terms of the publishers and games they can... : qtussin
By: Orange Pylon x Show Full PostOh, good. I can still get my games!Sep 22, 2010 12:57pm PDTOh, good. I can still get my games! : Orange Pylon
By: slothdood x Show Full PostHow could I not forgive them? They're giving me Baldur's Gate!
Hell, if a marketing ploy like this is all it takes to get classic RPGs, I hope they do it again soon!Sep 22, 2010 12:37pm PDTHow could I not forgive them? They're giving me Baldur's Gate! Hell, if a marketing ploy like this is ... : slothdood
By: Beelzebud x Show Full PostI'm willing to bet that most of the people posting that GOG "lost a customer" with this stunt, have never even bought a game from GOG in the first place.Sep 22, 2010 12:37pm PDT
By: NickDelios x Show Full PostThis marketing ploy just cost them a future customer.Sep 22, 2010 9:57am PDT
Thread Truncated. Click to see all 15 replies.
^^ This is exactly why this whole marketing ploy will work despite the legitimate backlash. : pillzer
you sir FAIL. : vujinovicm
By: Happy Doodle Muffin x Show Full PostWe got trolled.Sep 22, 2010 10:03am PDTWe got trolled. : Happy Doodle Muffin
By: omwibya x Show Full PostI saw the conference, it was funny as hell. dressed like monks they started with an apology "we have sinned,forgive us" while bowing their heads. I wish more publishers would have this sense of humor. They announced that their long term goal was to be the nr 1 alternative to STEAM so that's a pretty hefty goal.
Also I had games purchased and was not bothered by the site shutting down, but maybe that's because I always back-up my games. I can see though why some people were bothered. Still, love gog.com better than steam.Sep 22, 2010 10:08am PDTI saw the conference, it was funny as hell. dressed like monks they started with an apology "we have sin... : omwibya
By: Sideways Bob x Show Full PostOkay, they dressed up like monks to apologize. I'll forgive them.Sep 22, 2010 11:41am PDT
By: wytefang x Show Full PostPretty dumb gag to pull. It's clear that it lost them some customers. Clever stuff there, GOG.Sep 22, 2010 11:40am PDT
By: azuvatar x Show Full PostI think the people more pissed off about this whole thing are the ones who haven't downloaded their catalog off the site.
Ever since I realized Steam simply grants you a license to use the games and is not in any obligation of letting you re-download them once the service is out of business, I've made it a practice to immediately download/back up anything I buy on any digital media outlet.
I'm aware that with GOG you're supposed to own the game, not a license, but truth is they could go out of business or change policies just like that, and this, being a PR stunt and all (a distasteful one at that), just reassures me of that practice: buy and download right away.Sep 22, 2010 11:30am PDT
By: kodt x Show Full PostI think it is funny people are mad they were trolled for one week by GOG when every other DD service trolls you for eternity with DRM.Sep 22, 2010 10:48am PDTI think it is funny people are mad they were trolled for one week by GOG when every other DD service trol... : kodt
By: jad3d x Show Full PostThis company is based in Poland iirc, seems this was a poorly translated PR stunt...Sep 22, 2010 10:09am PDT
By: pimpium x Show Full PostI dont care as long as Dungeon Keeper 1 and 2 appear at some point.Sep 22, 2010 10:43am PDT
By: icedcool x Show Full PostBest pr stunt ever.Sep 22, 2010 10:39am PDTBest pr stunt ever. : icedcool
By: dante2010 x Show Full PostThis is up there with the "John Romero is going to make you his bitch" ad campaign.
Sep 22, 2010 10:16am PDTThis is up there with the "John Romero is going to make you his bitch" ad campaign. : dante2010
By: Onward, to futility! x Show Full PostSo stupid.
I mean, I am happy they aren't shutting down and I still love the idea of GoG and will buy from them still (starting tomorrow with BG, likely!), but I really don't see what this ridiculousness was supposed to accomplish. All it did was piss everyone off.
Guys, when your next big change occurs, please treat us like the customers we are. :|Sep 22, 2010 9:53am PDTSo stupid. I mean, I am happy they aren't shutting down and I still love the idea of GoG and will buy ... : Onward, to futility!
By: vujinovicm x Show Full Postare you people crazy? we don't care that you won't buy any more of their games, your loss. baldur's gate is coming.
Sep 22, 2010 10:31am PDT
By: st4rdog x Show Full PostIt was good marketing. I hadn't heard of it before, but I the gaming press haven't shut up about it for the last however many days.Sep 22, 2010 10:21am PDTIt was good marketing. I hadn't heard of it before, but I the gaming press haven't shut up about it for t... : st4rdog
By: T-900 x Show Full PostYou grumpy bastards.
You got pranked. Now stop whining =P
I love GoG more than ever for having an evil sense of humour and making us all worry.
Learn not to take anything for granted in future. Be grateful for a company as good as GoG, bringing life to old games that are otherwise so hard to acquire or get working, and giving them away for such low prices.Sep 22, 2010 10:28am PDT
By: Walterbennet x Show Full PostWow... What an incredible surprise...
Nothing about this bullshit marketing nonsense changes my opinion of the service they offer. They still rock, and have an incredible selection. Also, W00t for Baldur's Gate, though I have no desire to play the original. I'd rather jump in with BG2 once/if they get that.Sep 22, 2010 10:13am PDT
You must be logged in to post.


text:
Genie New Image Bras (3 Pack) - Black/White/Nude
- Low stock, selling fast
92 reviews
- Delivery
Genie New Image Bras - As seen on TV!
The New Image Genie Bra provides comfort, support and style for every woman.
Sizing is simple with no need for chest measurements or cup sizes - you simply pick your UK Dress size for a comfortable, supportive bra that custom conforms to your unique shape. This set includes a black, nude and white bra plus six soft insert padsColours: Black/White/Nude. 96% polyamide, 4% elastane. Machine washable.
• No wires, hooks or adjusting straps
• Wide straps and comfort band gently mould and conform to any shape
• Soft and comfortable fabric
• 360 degree wide comfort band for lift and support
• The BONUS soft full coverage support pads provide added lift
• The seamless cups mean it won't show through clothing
• The Genie Bra can double as a camisole, great for under blouses or party tops
• Includes black, nude and white – so you have one for every outfit!
These New Image Genie bras are safe to machine wash and dry. It is recommended that they are washed on a cold or delicate cycle and dried on a low setting. Remove Pads before washing.
Genie Cami Shaper
- Low stock, selling fast
8 reviews
- Delivery
Genie Cami Control Shaper
This 3-in-1 bra, camisole and shaper is a versatile addition to your everyday underwear wardrobe and we love the comfortable design for all day wear.
This Genie camisole shaper eliminates layers and smoothes out any rolls and bulges. The magic pouch allows you to slip in removable support pads for extra lift and coverage. The form fitting seamless construction is made from breathable comfort stretch fabric for maximum comfort.
Wear this Genie cami shaper over a sleeveless cotton vest top or a short sleeve tee.
Useful info:
- Camisole shaper by Genie
- Lace trim; eliminates layers
- Smoothes bumps and bulges
- Magic pouch for support pads
- Form fitting seamless construction
- Breathable stretch comfort fabric
Genie Milana Bras (2 Pack)
- Low stock, selling fast
9 reviews
- Delivery
Genie Camisole Milana Bras (2 pack)
In stretch lace these Milana bras by Genie can double up as a stylish camisole, making them a versatile underwear addition.
These Milana bras feature stretch lace and there are no underwires, hooks or adjusting straps. The Milana bra features a magic pouch to slip in removable modesty pads for a little extra lift and coverage. These form fitting bras have a seamless construction that looks great under clothes.
Wear these Genie Milana bras under vest tops, fitted tees or tunics.
Useful info:
- Milana bras by Genie
- Value pack of two bras
- Doubles up as a cami
- Stretch lace fabric
- No underwires or hooks
- No adjusting straps
- Magic pouch for modesty pads
- Seamless construction; form fitting
Genie Lace Genie Bras (2 Pack)
- Low stock, selling fast
11 reviews
- Delivery
Lace Genie Bras (2 pack)
In a pack of two these lace Genie bras are an excellent value buy - perfect for adding style and comfort to your everyday underwear wardrobe.
The Genie bra provides the ultimate comfort, support and style for every woman with the added touch of a delicate lace trim around the neckline. There are no wires, hooks or adjusting straps, resulting in the ultimate comfort. Wide straps and a comfort band gently mould and conform to any shape offering lift and support. The seamless cups won't show through clothing and the soft, full coverage support pads provide added lift.
This Genie bra in lace can double as a camisole and is great for wearing under blouses. This pack contains 1 black bra and 1 white bra.
Useful info:
- Genie lace bras (2 pack)
- Delicate lace trim to neck
- No wires, hooks or adjusting straps
- Features wide straps and a comfort band
- Gently mould to your shape
- Offer lift and support; seamless cups
- Full coverage with added support pads


text:
By Taryn AsherFOX 2 News Reporter
UPDATE: FOX 2 News has learned that all of the suspended employees are now back to work.
SOUTHGATE, Mich. -- On October 8, a woman living at Southgate Manor claims she was raped by a black man. Southgate Police confirmed the report and say they are investigating. Meanwhile, we've learned black male workers at the nursing home have been suspended."We don't have a statement at this time," said the manager at Southgate Manor. He referred us to owner Reginald Hartsfield, president of Advantage Management Group. He claimed safety is their number one priority and without an identification of the suspect, they had to suspend every black man in every department that would have contact with the alleged victim."I get a description of the alleged assailant, we suspend the people that fit that description, and in this particular case the description was vague and basically they said it was a black male," said Hartsfield by phone. "Temporary suspension with pay while we conduct our investigation.""That's shocking to me," said Deadra Clemens."Very disrespectful against black people," Gary Clemens said.Their father is a resident of Southgate Manor. Deadra even worked there at one time."They don't have (any) proof," Deadra Clemens remarked. "You can't go off what one of the residents say. Who knows if she (has) Alzheimer's, dementia or if she was in her right mind.""Do an investigation and then I say find out who really did it," said Gary Clemens. "Don't just suspend every black man."Hartsfield assured us they would have taken the same approach if it was a white man or even a woman. He said once an employee is ruled out as a suspect, they will be brought back to the job."I'm a black male myself, so I know how it sounds, but also as a nursing home administrator, I know what our regulations are and what we have to do," he said.One man has already been brought back.Hartsfield, who owns a total of eight nursing homes, says he is fair employer who has a very diverse workforce. He's just trying to do what's right.
KSAZ-TV & KUTP511 W. Adams St.Phoenix, AZ 85003Phone: (602) 257-1234Fax: (602) 262-0177


text:
Brittle-Brittle Gourmet Peanut Brittle - 42 oz.
Item #: 247920 |Model #: 062406 |
Olde-Fashioned Hand Dipped Gourmet Peanut Brittle. All natural and made with honey, it contains no preservatives.
- All-natural and hand made
- Gourmet quality
- Full of large top quality peanuts
- Light and crunchy easy to chew
- Never hard or sticky
- Genuine home made taste and texture
- Made with honey with no perservatives added
Assembled Country
Component Country
Ask & Answer
Warranty InformationThis product is covered by the Sam's Club Member Satisfaction Guarantee.
There is no additional information available for this item.


text:
More serious and deliberate than most, it's likely that the Capricorn pet will live to a ripe old age. Why? Well, for one, there's no risk-taking behavior going on with this pup. The Capricorn pet will plod along, amusing itself by watching the other animals as they play to their heart's content.
What keeps this animal happy is helping out and working hard. Need that paper fetched? The Cap dog will do it daily. Want those barnyard animals to stay in lock step? The Cap horse will see to it that everyone stays together. Stable and serene, the Cap pet will appreciate a comfortable home and a happy family. These animals won't need much exercise, either -- for them, work is exercise!
This is an animal that really loves to feel needed, so don't be reluctant to dole out those chores. Very self-controlled, the Cap pet is easy to house-train and will know the importance of following the family rules. Self-reliant as well, this is a pet that will do just fine back home while Mom, Dad, and the kids take a family trip. While the Cap pet doesn't need much touch or love, it does like to be neat and clean, so brush this pet regularly. Watch their bones and teeth, too, as these areas may require special attention.
Unlock the principles of karma and transform your future with a free sample Karma Reading from Astrology.com.
*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.


text:
You are visiting our UK site. Click here to view our US site
Bleeding Needles
Below is a selective range of high quality bleeding needles.
Bleeding Needles
Lancet PenEasy to use, press the trigger on the top of the p...
Price: £10.95
[more info]
Blood letting Lancet Needle (100 per box)Blood letting Lancet Needle (100 per box)
Price: £4.99
[more info]
Subscribe To CMT
Shopping Basket
Your basket is empty!
Change Language
Change Currency
Events Calendar
Korean Hand Therapy with Jong Baik in London 04/09/2014-09/09/2014
Korean Hand Therapy (KHT) is unique when compared to other hand reflexology... [more]
Master Tung Acupuncture Parts 1&2 with Philip Weeks - Novemeber 7th/8th
A very practical 2 day workshop with lots of practise!. Tung Acupuncture is well known for its quick and spontaneous results... [more]


text:
call now 01446 772614
STORAGE DESIGN LIMITED is a business to business supplier of storage systems, materials handling equipment and associated products. We are often known as a storage system specialist.
This business has grown over a period of 25 years, establishing a sound understanding of our clients needs and requirements.
You should find we are very knowledgeable with respect to our products and we always like a challenge, so please give us a call.
We supply a very large range of products from a single plastic container through to a complete warehouse installation.
Storage Design Limited is an 'independant distributor' therefore not tied to a single source which means we can direct our customers to the best possible solutions. For example one of our speclized subjects is LOCKERS which means we now supply 12 different manufacturers lockers, We have worked closely with some locker manufacturers helping to develop their ranges by product testing in real life situations. We find we have become experts in locker locking options, testing security and function !
Our specialized areas of activity:
Our sales office is based in South Wales in the market town of Cowbridge, located centrally between Cardiff and Bridgend which gives us good access to the M4 for Swansea and Neath heading west or Newport and Bristol heading east.
What you may not know is that we supply throughout the UK from Cornwall to Scotland. We have thousands of customers based all over the UK.
If you have a large project and require installation that should be no problem. If we cannot help we always know a man who can!
We also supply the trade with many products like Lockers, Pallet racking and Linbin plastic containers.
The linbin range of containers has been a fantastic product for us and our customers, They area a commercial product made to a very high standard.
Storage Design Limited is a storage systems specialist. For example the picture below is of a major project for a very large international printing company, We designed and created bespoke pallet boxes which craddled the print rollers, to protect their delicate print surfaces, these pallet boxes locate into numbered locations within the pallet racking for quick location. This concept has been developed further to create transport cases for the valuable print roller sets. The print rollers can be sent to different factories or sent for reworking knowing that they will be returned undamaged.
If you have a particular storage requirement we may have a simple storage solution. Stacked plastic containers can be used to create various complete wall storage. We have also created mobile units for storage in coldstores and walk-in freezers.
Container walls can be used for storage of small to medium sized products providing stock location and controll.