The striate cortex of the macaque monkey is subdivided into two independent and overlapping systems of columns termed "orientation columns" and "ocular dominance columns." The present paper is concerned with the orientation columns, particularly their geometry and the relationship between successive columns. The arrangement of the columns is highly ordered; in the great majority of oblique or tangential microelectrode penetrations the preferred orientations of cells changed systematically with electrode position, in a clockwise or counterclockwise direction. Graphs of orientation vs. electrode track distance were virtually straight lines over distances of up to several millimeters; such orderly sequences were often terminated by sudden changes in the direction of orientation shifts, from clockwise to counterclockwise or back. The orientations at which these reversals occurred were quite unpredictable. Total rotations of 180–360° were frequently seen between reversals. In tangential or almost tangential penetrations orientation shifts occurred almost every time the electrode was moved forward, indicating that the columns were either not discrete or had a thickness of less than 25–50 μ, the smallest order of distance that our methods could resolve. In penetrations that were almost perpendicular to the surface, the graphs of orientation vs. track distance were relatively flatter, as expected if the surfaces of constant orientation are perpendicular to the cortical surface. Stepwise changes in orientation of about 10° could sometimes be seen in perpendicular penetrations, each orientation persisting through several clear advances of the electrode, suggesting a set of discrete columnar subdivisions. The possibility of some kind of continuous variation in orientation with horizontal distance along the cortex was not, however, completely ruled out. Occasionally a highly ordered sequence was broken by an abrupt large shift in orientation of up to 90°. Shifts in ocular dominance occurred roughly every 0.25–0.5 mm and were independent of orientation shifts. In multiple parallel penetrations spaced closer than about 250 μ the slopes of the orientation vs. track distance curves were almost the same; reconstruction of these penetrations indicated that the regions of constant orientation are parallel sheets. On crossing perpendicular to these sheets, a total orientation shift of 180° took place over a distance of 0.5–1.0 mm. Column thickness, size of shifts in orientation, and the rate of change of orientation with distance along the cortex seemed to be independent of eccentricity, at least between 2° and 15° from the fovea. A few penetrations made in area 17 of the cat and in area 18 of the monkey showed similar orderly sequences of receptive‐field orientation shifts.


"TUMOR-TARGETING APTAMERS FOR THE TREATMENT OF PROSTATE CANCER" Enid W. Choi, B.S. December 2011 Prostate cancer is the most common type diagnosed among men in the United States. Random oligodeoxynucleotide (ODN) libraries are used to generate DNA aptamers by systematic evolution of ligands by exponential enrichment (SELEX). We explored the utility of guanine-rich libraries, and found that some had cancer-selective antiproliferative activity that generally correlated with G-quadruplex formation, nuclease resistance, and enhanced cellular uptake. We identified several proteins by mass spectrometry that bind to GC and cytosine ODNs. We compared the GT library with the classic random library for SELEX of whole prostate cancer cells and identified a new aptamer from the GT library with enhanced nuclease resistance and antiproliferative activity. We present evidence that ASI411, a known G-rich anticancer aptamer, inhibits prostate tumor initiating cells. This body of work supports the hypothesis that G-rich ODNs are well suited to the development of new aptamers in the treatment of cancer.


An analgesic spray was used in 60 children scheduled to undergo lysis of glanular adhesions, lysis of labial adhesions, or excision of glanular skin bridges, and worked about 30 minutes faster than analgesic cream.


Cross docking is one of the options to reduce lead times and inventories and to improve customer response time in supply chains. Cross-docking centres are dynamic environments where products arrive, are regrouped, and leave the same day. In this paper we focus on the process of short-term storage of unit-Ioads in a cross-docking environment. The goal is to determine temporary storage locations for incoming unit loads such that the travel distances of the forklift trucks with these unit loads are minimised. We model this problem as a navel application of the minimum cast flow problem and show the applicability of the model for different types of layouts and priorities.


ABSTRACT With the massive growth of the internet, product reviews increasingly serve as an important source of information for customers to make choices online. Customers depend on these reviews to understand users' experience, and manufacturers rely on this user-generated content to capture user sentiments about their product. Therefore, it is in the best interest of both customers and manufacturers to have a portal where they can read a complete comprehensive summary of these reviews in minimum time. With this in mind, we arrived at our first objective which is to generate a feature-based review-summary. Our second objective is to develop a predictive model to know the next week's product sales based on numerical review ratings and textual features embedded in the reviews. When it comes to product features, every user has different priorities for different features. To capture this aspect of decision-making, we have designed a new mechanism to generate a numerical rating for every feature of the product individually. The data have been collected from a well-known commercial website for two different products. The validation of the model is carried out using a crowd-sourcing technique.


Pole phase modulation (PPM) is one of the effective technique to control speed and torque of multiphase machines. This paper presents the winding details and finite element analysis (FEA) of 15 phase squirrel cage induction motor (IM) drive with 1:3:5 speed ratios using PPM. The proposed 15 phase IM with 60 stator slots and full pitched winding is able to run in five different pole-phase combinations with best utilization of copper. The 15 phase IM fed by a 15 leg inverter is operated in 15 phase 4 pole, 5 phase 12 pole, 3 phase 20 pole, 5 phase 4 pole and 3 phase 4 pole combinations. In addition Generalization of PPM is revisited in this paper to add an extra constraint on the pole ratio by showing an exception for the already proposed generalization of PPM. The operation of the proposed drive for five different pole-phase combinations with three possible speeds is verified by FEA simulation using Ansys Maxwell 2D (FEA package for electromagnetic design) and Simplorer for 2kw IM drive prototype with 10Nm load torque.


In the early days of the modern scientific revolution, Galileo and his contemporaries issued a crucial challenge to those concerned with the nature of human language, a challenge that was scarcely recognized until it was taken up in the mid-20th century and became the primary concern of much of the study of language. For short, I will refer to it as the Galilean challenge. These great founders of modern science expressed their awe and wonder at the fact that language permits us to construct "from 25 or 30 sounds an infinite variety of expressions, which although not having any resemblance in themselves to that which passes through our minds, nevertheless do not fail to reveal all of the secrets of the mind, and to make intelligible to others who cannot penetrate into the mind all that we conceive and all of the diverse movements of our souls."1


Background. CHEK2-associated neoplasms account for a significant proportion of hereditary breast cancer (BC) in Russia. The phenomenon of somatic deletion of the normal allele of a gene affected by a hereditary mutation, or loss of heterozygosity (LOH), is a frequent mechanism of complete inactivation of the corresponding protein, which is realized during the development of hereditary breast carcinomas. The contribution of the LOH phenomenon to the pathogenesis of CHEK2-dependent tumors is poorly understood, and almost all available data concern only one type of mutations - CHEK2 1100delC.
The aim of the study was to characterize the frequency of LOH in breast tumor tissues from carriers of the three types of CHEK2 alterations: CHEK2 1000delC, CHEK2 IVS2+1G>A, and CHEK2 del5395.
Materials and methods. LOH analysis was performed in a group of 50 breast cancer cases from women carrying CHEK2 1000delC (n = 19), CHEK2 IVS2+1G>A (n = 12), and CHEK2 del5395 (n = 19) mutations. Detection of LOH was carried out using a combination of methods that directly analyze the mutation locus (allele-specific PCR, Sanger sequencing, digital droplet PCR), and assess the status of single nucleotide polymorphisms surrounding the CHEK2 gene (digital droplet PCR).Results. The frequency of the LOH phenomenon in the studied cohort reached 27/50 (54%). Loss of heterozygosity was observed in 10/19 (52.6%) CHEK2 1000delC-associated, 6/12 (50%) CHEK2 IVS2+1G>A-associated, and 11/19 (57.9%) CHEK2 del5395-associated tumors. In one carcinoma from a carrier of the CHEK2 IVS2+1G>A alteration, the loss of mutated allele was confirmed. The main clinical and pathological characteristics were compared between tumors with loss and retention of heterozygosity. This comparison did not reveal any significant differences.Conclusion. Loss of heterozygosity is observed in about half of breast carcinomas arising in CHEK2 mutation carriers; the frequency of this phenomenon does not differ between three types of CHEK2 genetic defects.


The incidence of cutaneous malignant melanoma (MM) is increasing worldwide. Regular self-skin examination can assist in the early detection of MM. However, identifying new or changing lesions on nonvisible body sites (NVBS) can be difficult. Research investigating MM on NVBS is limited. The aim of this study was to compare the features of MM on NVBS with visible body sites (VBS) to add data to this patient cohort. We performed a retrospective chart review to identify patients diagnosed with MM in our institution from 2019 to 2021. Clinicopathological features were extracted and analysed. NVBS was defined as areas including the posterior scalp, ears and neck, posterior shoulder, back, buttocks, posterior thigh and plantar aspect of the feet. Statistical analysis was performed using SPSS (IBM). A total of 162 patients were included in this study; 45.1% (n = 73) were male. Patients with MM on NVBS were statistically significantly younger (median age 59 years) compared with patients with MM on VBS (median age 66.5 years; P < 0.05). Thirty-seven per cent (n = 60) of lesions were found on NVBS. Twenty-eight per cent (n = 17) of MMs on NVBS were identified incidentally on total body examination (TBE) in the clinic by a dermatologist. There was a statistically significantly higher number of patients with melanoma in situ on VBS (n = 44; 27.1%) compared with NVBS [n = 17; 10.5% (P < 0.01)]. A higher proportion of patients with MM on NVBS had a Breslow thickness > 1 mm (n = 23; 38.3%) vs. VBS (n = 30; 29.4%). This study demonstrates a higher number of MM diagnosed incidentally following TBE compared with previous research. Our study focused on a MM-specific cohort who may, potentially, have had lethal skin cancers missed in 28% of cases if TBE was not carried out. Our findings also show that patients are more likely to have noninvasive tumours detected on VBS but more advanced disease on NVBS, further emphasizing the importance of TBE. This study suggests that high-risk patients could benefit from specific surveillance programmes that encourage regular self-skin examination and periodic TBE by a consultant dermatologist to enable early detection and treatment of MM. This study was limited by its retrospective design and a small number of patients from a single institution. We recommend an increased emphasis on patient education on the importance of self-examination which, when complemented by physician-directed TBE, plays a valuable role in the early detection of MM on NVBS. This study provides guidance in designing pathways to target high-risk groups to avoid delays in the diagnosis of MM. Further research to explore trends of MM on NVBS may enable targeted education campaigns in the future.


With the rapid development of tourism,tourism planning and design has been widely practiced in China.At the same time,the planning idea,content and method also keep developing.This paper briefly retrospects the developing course of tourism planning and designs,and makes some comments on the impacts of the Systematic Theory and the Ideas of Sustainable Development.Under the macro-background of China that many regions are in their urgent need to develop,much attention must be paid to the social and economic factors in tourism planning and design.Thereby,by developing "comprehensive tourism",tourism planning and development capacity can be strengthened.Based on the already-existed research results,the connotation of "comprehensive tourism" is more clearly explained and the content is generally divided into several aspects,such as comprchensne resources,comprehensive tourism industrial area,comprehensive production chain,comprehensive market and comprehensive system,etc.Then,the industrial conformity and space conformity are emphatially elaborated.It's point out in the end that it's of great significance to make an in-depth research on the "great tourism".


A new type of dual‐band balun bandpass filter (balun BPF) based on length reduced coupled lines and shunt open‐ended stubs is proposed in this letter to realize integration of balun and bandpass filter with dual‐band property for miniaturization and multifunction of modern RF front‐ends. Besides design details presented, a balun BPF centered at 2.45 and 5.25 GHz with a 130 MHz bandwidth of each passband is implemented by the proposed method. Desired balun‐type and filter‐type functionalities are observed at both passbands with great out‐of‐band rejection between them. © 2014 Wiley Periodicals, Inc. Microwave Opt Technol Lett 56:2358–2360, 2014


∗ This paper was prepared for the special issue of "Ruch Filozoficzny" dedicated to professor Żeglen. Professor was advisor of my Master Thesis (on phenomenal consciousness) and PHD Thesis (on embodied cognition). With gratitude for her support and trust in my – sometimes a little bit slow – work, I want to dedicate her this paper. While working on PHD Thesis I had an opportunity work with professor Żegleń and Tomasz Komendziński (and colleagues such as Jacek Podgórski and many others) on the first program in cognitive science studies in Nicolaus Copernicus University in Toruń. Together with Tomasz Komendziński we proposed that an important part of this studies should be lectures in "Philosophy in Cognitive Science", and for two years, I had the great pleasure of conducting exercises for these lectures. Despite the fact that my approach to the relation between philosophy and cognitive science dramatically changed from that time, that period was extremely important for my thinking about issues which I describe in this article. 1 Contrary to the opinion expressed in most of the papers providing an introduction to cognitive science (Keith Frankish, William Ramsey, The Cambridge Handbook of Cognitive Science (Cambridge University Press, 2012); Jay Friedenberg, Gordon Silverman, Cognitive Science: An Introduction to the Study of Mind (Sage, 2011)), the interdisciplinary nature of the field is not obvious or self-evident (Jamie Cohen-Cole, "Instituting the Science of Mind: Intellectual Economies and Disciplinary Exchange at Harvard's Center for Cognitive Studies", The British Journal for the History of Science 40, no. 4 (2007): 567–597; Harvey J. Graff, Undisciplining Knowledge: Interdisciplinarity Ruch FilozoFiczny


The adolescent's attitude and cognition on the influence,norm and reliability of internet will contribute to the analysis of their cognition on internet.The adolescent's cognition and choice of the socialization of internet lie in their needs,outlook of value and experience,which give rise to their specific conducts just like their choice of purpose,time and place and the unhealthy reading on internet.Education is considered as the best way to limit the scope of the negative effects of internet.So the adolescent,family and school should receive "internet well-treated" education,internet technology,moral and humanity education.Moreover,importance should be attached to the education of media quality so as to purify the growing environment of adolescent.


The article is reviewing current practice of municipal and production waste management licensing in Russia. Modern state of municipal waste utilization is described as most occurring type of waste and less controlled. Key problems of the industry are highlighted: absence of necessary infrastructure, high cost of collection and waste segregation, lack of legal requirements on waste processing, absence of effective economic mechanism for waste management; selfelimination of State from the given sphere, as result of all listed above only formal licensing of waste management process, what leads to multy-violation of legal requirements in the area. Possible solutions are proposed documents in force and planned legislation changes are presented, as well as absence of effective economic mechanism leading to waste treatment and use. Proposals given by Ministry of Natural Resources aimed on update of Federal Law "On production and consumption wastes" are detailed.


Uniform flower-like CdS was fabricated successfully using a facile hydrothermal approach without templates or additives. The formation process of the flower-like structures was investigated in detail. The as-prepared flower-like CdS exhibited good photocatalytic activity for the photodegradation of various organic dyes.


Summary The aim of the World Health Organisation's recently revised International Health Regulations [IHR] is to establish a global alert and response network for outbreaks of infectious disease and other public health threats with the potential for international spread. The rationalized and modernized IHR are a set of obligations and procedures for broad-based domestic and international public health collaboration to contain known risks, respond to unexpected ones, and improve national and international readiness through long-term sustainable capacity building at all levels. However, in the absence of significant changes to existing policies, operations, and capacities both within and among nations, compliance with the requirements of the agreement will remain challenging for many countries. This article briefly surveys the historical origins and the principal requirements of the revised IHR, with a particular focus on four key obligations: (1) to create an integrated national surveillance system; (2) to ensure timely reporting; (3) to prevent the application of excessive restrictive measures; and (4) to contribute to capacity-building in the developing world. Strategies for meeting the challenge of these obligations are proposed, as are recommendations for Canadian policy leadership in laying the foundations for effective


This study aimed to analyze the ethical dimension experienced by dentists in the professional practice of a city in Rio Grande do Sul, Brazil, in order to contribute to the improvement of the work of these professionals. This is a qualitative study with content analysis. A semi-structured interview was used to collect data and eight dentist participated in the sample. The results show that there are flaws in the understanding of the Código de Ética Odontológico (Dentistry Code of Ethics) by most dentists, and little knowledge of professional ethics, leading to a lack of reflections on their daily practice. The study suggests that ethical flaws may be related to the content taught in the training of professionals in which the healing practice was predominant with focus on the technical aspects and little emphasis on knowledge aimed at humanization, prevention and health promotion.


Stages of construction and functioning of medieval church architecture monument in Dagestan Gazi-Kumukh Dzhuma-Mosque are considered in the article. Authors refer to new data on newly revealed written sources in order to fi ll in the construction date of monument appeared in the VIII A. D.


The comprehensive utilization of low-grade diatomite resources and the effective treatment of printing and dyeing wastewater have attracted widespread attention. The combined scrubbing-magnetic separation-acid leaching-roasting process was used to increase the SiO2 content from 59.22% to 86.93%, reduce the Al2O3 content from 18.32% to 6.75%, and reduce the Fe2O3 content from 6.85% to 1.24% in the low-grade diatomite from Heilongjiang, China. The TiO2/g-C3N4/diatomite nanocomposite was prepared by a facile ultrasonic-thermal polymerization method. In this ternary structure, diatomite skeleton effectively increased the surface area with abundant adsorption sites, prevented g-C3N4 from restacking, and facilitated the separation of electrons and holes via the formation of TiO2/g-C3N4 heterojunctions. The degradation rate was 98.77%, 90.59%, and 89.16% for the three catalytic reaction cycles of the MB solution, respectively. The composite showed a high degradation rate of the MB solution after three cycles, which indicated that the composite had good recyclability. Through the free radical capture test, it was elucidated that O2−·, h+, and ·OH all played a role in the photocatalytic reaction of the TiO2/g-C3N4/diatomite to the MB solution, in which O2−· was mainly responsible for the photocatalytic oxidation mechanism, and the reaction kinetics were further investigated. This nanostructured TiO2/g-C3N4/diatomite composite has fascinating visible light catalytic activity and excellent stability.


Innovation carriers like scientific innovation flats and parks based on colleges or been cooperated with colleges,which looks forward to transforming scientific research achievements and outcomes to products,can benefit colleges to get to the fast track of continuous development,complete the reform of colleges running mode from the inside.Colleges can help themselves contribute to the local financial development;combine itself more closely and efficiently to the local surrounding business environment.The article had proved the possibility of built up college based innovation carriers from four directions and suggested four approaches to the construction of innovation carriers in Chinese colleges.


The main purpose of this paper is to contribute to our understanding of the conditions under which Business–nongovernmental organization (NGO) interactions lead to improvements in corporate social responsibility (CSR), by assessing the role that the stakeholder context of the firm plays in the processes. As a case study it takes an interaction process between one NGO and one company with both collaborative and confrontational traits, spanning eight years and two issue fields, palm oil and soy, which are characterized by varying stakeholder contexts. The analysis demonstrates that the business–NGO interaction induced a change from a direct to an indirect corporate responsibility, and clarifies how interdependencies between the company and other stakeholders than the NGO influenced the interaction. The stakeholder interdependencies vary per issue field: In some issue fields, the stakeholder context allows for effective, collaborative interaction between business and NGO, while in another issue field, characterized by different stakeholder interdependencies, collaborative, constructive interactionbetween the same business and the same NGO is not feasible and, in addition, less effective in terms of CSR than confrontational interaction.


The model of assessment in educational and vocational counseling is the "matching model." It inhibits developmental counseling. A stage-theory model is proposed instead and is case illustrated.


Accurate reconstruction of myocardial T1 maps from a series of T1‐weighted images consists of cardiac motions induced from breathing and diaphragmatic drifts. We propose and evaluate a new framework based on active shape models to correct for motion in myocardial T1 maps.


It is now three and one-third centuries since early English Baptists, under the leadership of such heroic saints as John Smythe, Thomas Helwys and John Murton, stepped forth from the misty muddle of English non-conformity (men who could not conform to the state church of Henry VIII and Elizabeth), uttered their deep convictions and provided for future progress by declaring: "God hath yet more light to break forth from His Holy Word." During the intervening years their convictions and principles, refined through thought and tears in study of that Holy Word, have won the loyalty of millions of souls around the world. These souls have realized the practical and spiritual wisdom of organizing themselves into co-operative bodies ranging in size from tiny local churches to the Baptist World Alliance. Always Baptists have persisted in their original emphases. At times the inevitable pull of personal ambition on some aggressive leaders and the centralizing argument for world-like efficiency have lured them toward a hierarchy, just as large numbers in the early churches were lured into the Roman system. Still, however, they hold to the great t ruths with which they started; namely, (1) the supreme authority of Scripture, (2) the fundamental importance of the individual believer, and of the local church, (3) the baptism by immersion of believers only, (4) the sufficiency of each soul to deal directly with God without priestly mediator and (5) the separation of church and state. These great principles, all taken absolutely together and applied vigorously, constitute both the strength and the distinctiveness of Baptists. Other denominations and sects have come to accept one or more of them and in that much are like us (e. g. the Presbyterians in America took up the battle for religious l iberty), but the principles are so vitally related that the lack of any one of them seriously weakens the rest of them. For example, to reject the baptism of be-


We propose a new state, strange color superconductivity, that appears in strange quark matter when total barion number density is fixed. In this state, heavy squarks, with a small Fermi surface, 'strangly' pair with light u or d quarks that have a larger nominal Fermi surface, opening a gap there. There are gapless states in the intermediate region. Strange color superconductivity might be realized in quark matter at intermediate densities in neutron stars. We expect a second order phase transition, as a function of increasing density, from this phase to color-flavor locked (CFL) quark matter.


ABSTRACT— Two patients with legs tremor present on standing, but none on walking or sitting, are reported. Tremor was not exclusive of orthostatism and was also evoked by strong tonic contraction of leg muscles. Synchronous EMG bursts were recorded in antagonistic muscle groups at 8‐10 Hz in the first patient and at 16 Hz in the second. EMG activity was synchronous in corresponding muscles of both legs. The occurrence of EMG activity was not influenced by stimulation of nerve afferent fibers. We suggest that this movement disorder may be an exaggeration of physiological tremor due to synchronization of motor units by spontaneous oscillations in central structures.


In this paper,the modified iteration method is successfully extended to investigate thenonlinear free vibration of corrugated circular plates with full corrugations.The analyticalrelation for the amplitude-frequency response of corrugated circular plates is obtained anddiscussions on the influences of geometrical parameters on vibration behaviours ofcorrugated circular plates are made.The present results are practically important in thedesign of elastic elements in precision instruments.


Part 1 Childhood - the complex, fantastic process of being born and becoming a person: what should happen - an overview pre-natal and peri-natal risk factors the special vulnerabilities of children and families. Part 2 Children's bodies - systems at work and play: the cardiovascular and pulmonary systems the nervous system the musculoskeletal system the visual and auditory systems the cognitive system the psychological system. Part 3 Special topics in paediatric occupational therapy: working in the neonatal intensive care unit children with feeding and nutritional problems the psychological system in adolescence children as burn patients children with traumatic brain injury children with cancer chronic illness, terminal illness and closure.


. Wiadnya DGR, Harlyan LI, Rahman MA, Mustikarani SMI, Nadhiroh ENS, Taufani WT. 2023. Stock status and supporting species of anchovy fisheries in the northern of East Java, Indonesia. Biodiversitas 24: 4775-4782. Anchovy, a commercial fish with high demand in local and international markets, was selected as the Unit of Assessment (UoA) of the Fisheries Improvement Project (FIP) based on the priority fisheries consultation process under the Marine Stewardship Council certification in Indonesia. One of the criteria is the availability of stock status and information about supporting species. This research was conducted from January to May 2022 at Lekok Fishing Port, Pasuruan, and Karangagung Fishing Port, Tuban, using primary data collection methods, including a fishery survey to obtain data species composition data and fishing coordinates. The secondary data were the catch-effort data from 2013 to 2021 collected from both fishing ports. Data analysis was carried out by the surplus production models, Schaefer and Fox model, to determine the total allowable catch (TAC) and the exploitation rates of anchovy fisheries. The participatory mapping method was carried out to obtain data on the distribution of fishing grounds and catch composition. The exploitation rate of anchovy ( Stolephorus commersonnii ) and large anchovy ( Encrasicholina punctifer ) landed in the Lekok fishing port was 76% and 75% (moderate), respectively. In this situation, fishing efforts can still be increased, as TAC value for anchovy fisheries' sustainability. On the other hand, the exploitation rate of anchovy in the northern waters of Tuban is 105% (over-exploited), which is necessary to reduce fishing efforts for its sustainability. The classification of supporting species resulted in 19 identified species in the Lekok fishing port, covering three target species: two endangered threatened and protected (ETP) species, two main primary species, six minor primary species, one major secondary species, and five minor secondary species. While in Karangagung fishing port, eight species were identified, consisting of 1 major primary species, five minor primary species, and two minor secondary species. The supporting species' information is required to complete FIP Anchovy fisheries.


Summary Background— Increasing concentrations of atmospheric carbon dioxide (CO 2 ) lower the content of zinc and other nutrients in important food crops. Zinc deficiency is currently responsible for large burdens of disease globally, and those populations who are at highest risk for zinc deficiency also receive most of their dietary zinc from crops. By modeling dietary intake of bioavailable zinc for the populations of 188 countries under both an ambient CO 2 and elevated CO 2 scenario, we sought to estimate the impact of anthropogenic CO 2 emissions on the global risk of zinc deficiency. Methods— We used established methods of estimating per capita per day bioavailable intake of zinc for the populations of 188 countries at ambient CO 2 concentrations. We then modeled zinc intake at elevated and ambient CO 2 concentrations and estimated the risk for inadequate zinc intake among the populations of different nations under the two scenarios (ambient and elevated CO 2 ) by calculating population-weighted estimated average requirements (EARs), and using the EAR cut-point based method. We then compared the size of the populations at risk under the two scenarios in each country. Findings— Anthropogenic emissions of CO 2 are likely to place between 132 million—180 million people at new risk of zinc deficiency by around 2050. The people likely to be most affected live in Africa and South Asia, with nearly 48 million residing in India alone. Global maps of increased risk show significant heterogeneity and can be used to help guide interventions aimed at reducing this vulnerability. Interpretation— Our results indicate that one heretofore unquantified human health impact associated with anthropogenic CO 2 emissions will be a significant increase in the population at risk for zinc deficiency.


Abstract We present a proof of the Moon in a puddle theorem, and use its key lemma to prove a generalization of the four-vertex theorem.


We report herein a rare case of metastatic Crohn's disease involving the penile and scrotal skin in a 56-year old man. We review the literature about this rare entity and describe its clinicopathological characteristics.


1. A pharmaceutical controlled-release composition, comprising fluvastatin or a salt thereof and at least one hydrophilic polymer, wherein the hydrophilic polymer is not hydroxypropyl methylcellulose, and the composition is substantially free of hydroxypropylmethylcellulose. ! 2. The composition of claim 1, wherein the hydrophilic polymer is at least one non-ionic hydrophilic polymer. ! 3. A composition according to claim 1 or 2, substantially free of an alkalizing stabilizing agent. ! 4. The composition of claim 1 or 2, wherein the fluvastatin is fluvastatin sodium. ! 5. A composition according to claim 1 or 2, wherein the fluvastatin or a salt thereof is a hydrate, solvate or amorphous form of fluvastatin. ! 6. A composition according to claim 1 or 2, comprising fluvastatin or a salt thereof in an amount from about 10 to about 50% by weight of the composition. ! 7. The composition of claim 2, wherein at least one non-ionic hydrophilic polymer is present in an amount of from about 5 to about 40% by weight of the composition. ! 8. A composition according to claim 2, wherein at least one non-ionic hydrophilic polymer is selected from the group consisting of cellulose derivatives, poly (ethylene oxide), polysaccharides, and combinations thereof. ! 9. A composition according to claim 8, wherein the cellulose derivative is selected from the group consisting of carboxymethylcellulose, methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, and combinations thereof. ! 10. The composition of claim 8, wherein the polysaccharide is selected from the group consisting of xanthan gum, inulin, guar gum, chitosan, tsertoniya, carrageenan, starch, starch derivatives and combinations thereof. ! 11. The composition of claim 8, wherein


Microwave interferometry is a tool for precisely measuring distances or vibrations of a target in industrial applications. Distance resolutions in the range of few micrometers and measurement value update rates of several tens of kilohertz are feasible. These parameters can only be achieved, if careful compensation of non-ideal effects is conducted. In this paper the basics of Six-Port based microwave interferometry as well as selftest techniques will be presented. Exemplarily, linearization of the operating point of the diode detectors and frequency estimation of the radar signal will be shown.


<jats:p>The layered material SrCu<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>(BO<jats:inline-formula><jats:alternatives><jats:tex-math>_3</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>3</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>)<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula> has long been studied because of its fascinating physics in a magnetic field and under pressure. Many of its properties are remarkably well described by the Shastry-Sutherland model (SSM) - a two-dimensional frustrated spin system. However, the extent of the intermediate plaquette phase discovered in SrCu<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>(BO<jats:inline-formula><jats:alternatives><jats:tex-math>_3</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>3</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>)<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula> under pressure is significantly smaller than predicted in theory, which is likely due to the weak interlayer coupling that is present in the material but neglected in the model. Using state-of-the-art tensor network methods we study the SSM with a weak interlayer coupling and show that the intermediate plaquette phase is destabilized already at a smaller value around <jats:inline-formula><jats:alternatives><jats:tex-math>J''/J\sim0.04-0.05</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>J</mml:mi><mml:mi>″</mml:mi><mml:mi>/</mml:mi><mml:mi>J</mml:mi><mml:mo>∼</mml:mo><mml:mn>0.04</mml:mn><mml:mo>−</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math></jats:alternatives></jats:inline-formula> than previously predicted from series expansion. Based on our phase diagram we estimate the effective interlayer coupling in SrCu<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>(BO<jats:inline-formula><jats:alternatives><jats:tex-math>_3</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>3</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula>)<jats:inline-formula><jats:alternatives><jats:tex-math>_2</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi /><mml:mn>2</mml:mn></mml:msub></mml:math></jats:alternatives></jats:inline-formula> to be around <jats:inline-formula><jats:alternatives><jats:tex-math>J''/J\sim 0.027</jats:tex-math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>J</mml:mi><mml:mi>″</mml:mi><mml:mi>/</mml:mi><mml:mi>J</mml:mi><mml:mo>∼</mml:mo><mml:mn>0.027</mml:mn></mml:mrow></mml:math></jats:alternatives></jats:inline-formula> at ambient pressure.</jats:p>


Video capture is becoming more and more widespread. The technical advances of consumer devices have led to improved video quality and to a variety of new use cases presented by social media and artificial intelligence applications. Device manufacturers and users alike need to be
 able to compare different cameras. These devices may be smartphones, automotive components, surveillance equipment, DSLRs, drones, action cameras, etc. While quality standards and measurement protocols exist for still images, there is still a need of measurement protocols for video quality.
 These need to include parts that are non-trivially adapted from photo protocols, particularly concerning the temporal aspects. This article presents a comprehensive hardware and software measurement protocol for the objective evaluation of the whole video acquisition and encoding pipeline,
 as well as its experimental validation.


The present invention relates to a hybrid device of the excavator, the engine and the motor-front work area dental turning through the hydraulic line has three electromagnetic control valve for supplying a discharge pressure oil of the main hydraulic pump connected to a generator consisting of a boom, arm and bucket of the excavator and the parallel distributed connected to the apparatus and driving mechanism, the front work devices, is an electronic control baelbi master valve installed in the hydraulic lines connected to the turning hydraulic motor and the travel motor, which is controlled by the controller the other hand, hydraulic pressure to the return line of the boom cylinder consists of a generator is installed and, turning the structure the accumulator to one hydraulic line of the hydraulic motor installed in motor and motor. The invention here can be independent of the speed control to so control the actuator via the distributed control valve by controlling the flow of pressure oil flowing in each actuator by using the electronic control baelbi master valve can be line to secure the central area load control and the property is easy, the swing of the excess pressure of the high pressure to return in the device, with also stores the recovered energy to the accumulator to activate the pressure passage hydraulic motor and the electric motor that is recovered from the boom cylinder recovered by conversion into electric energy so, to reduce the energy loss of the excavator, and makes it possible to improve the fuel economy. The hybrid device, the electronic control baelbi master valve of the excavator, a motor-generator


The present invention relates to a low-pressure reactive device voltage sensitivity of one kind of automatic voltage control substation statistical methods are automatic control technology power system voltage. First, real-time monitoring transformer high and low side reactive and substation substation, medium and low-side bus voltage value; when no power equipment performance, statistical transformer low voltage side reactive apparatus operation transformer low voltage side, a time low-voltage side of the transformer reactive power variation value, the substation high, medium and low-side bus voltage value changes, the calculated results of the voltage sensitivity of the reactive reactive power transformer low voltage side equipment and an operation to save the database. Timing Statistics sensitivity RMS 30 days, were calculated according to the average reactive voltage sensitivity valid statistical frequency and the reactive voltage sensitivity, current and reactive power and voltage control sensitivity of the AVC system using corrected. By substation high, medium and low side bus voltage without reactive constantly modify the sensitivity, so that more precise control AVC.


The Mauritius Family Planning Association (MFPA) was formed in 1957 in response to an average annual growth rate of about 3% which rapidly made Mauritius 1 of the most densely populated countries in the world more than 1200 persons/sq mile. This growth was the result of a systematic campaign to eradicate malaria started in 1948. The crude death rate fell from 27.1/1000 in 1944 to 15.8 in 1954 while the birthrate remained at 36/1000. The MFPA advocated all available methods of contraception. In 1963 a largely Catholic organization was formed to encourage use of the rhythm method Action Familiale. In 1965 the International Planned Parenthood Federation began supplying a yearly grant. A government program was also implemented. During the 2nd half of the 1960s fertility began to decline the number of acceptors grew from about 3000 in 1965 to 15000 in a single year in 1973 and the mean age of 1st acceptors dropped from 30.5 to 26.5. By 1975 nearly 60% of new acceptors had fewer than 3 living children. However in 1974 the birthrate suddenly increased from 22.7 to 27.1 and gave rise to concern about the program. Analysis shows 2 possible causes: an increase in the number of women reaching marriageable age and an increse in the number of marriages due to a gain in the gross national product. In 1975 birthrates showed a slight drop to 25.1. Since most of these births are to women with fewer than 3 children and since the large numbers of girls born immediately after World War 2 are now reaching marriageable age the crude birthrate in Mauritius is likely to fluctuate around the 1975-1976 rate for a few years. Te National Family Program is consequently focusing on younger couples. At the same time as fertility has been falling other programs have cut the infant mortality ratre to nearly 1/4 the 1972 level and have doubled life expectancy from about 30-35 years in 1945 to about 65 years in 1975. This plus more than 90% of the population enrolled in school will aid development and help encourage lower fertility.


ABSTRACT REFRIGERATION has long been the primary method of retaining market quality in shell eggs. The fundamental reasons for employing lower temperatures have not been adequately elucidated. This lack of information has indirectly resulted in the development of practices which are designed mainly to lower the temperature without adequate consideration for other effective means of retaining specific quality attributes. Gathering and holding eggs in baskets affords rapid cooling. However, excessive ventilation before, during, and after cooling fosters the loss of carbon dioxide (CO2). Cotterill and Gardner (1957) compared the results of gathering and holding eggs at 58°, 74°, and 94°F. in baskets and in sealed buckets. The buckets contained a desiccant to retard microbial growth. They reported that eggs gathered in buckets had higher candled scores, higher Haugh units, lower pH, and comparable shell surface bacterial counts, except when stored at 94°F. for periods longer than four days. Storage temperature had . . .


Multidentate ligands involving tethered pyridyl groups coordinated to transition metal ions have been frequently used to mimic the 3-histidine (3H), 2-histidine-1-carboxylate (2H1C) brace motifs or other combinations of histidine and carboxylate endogenous ligating residues found in bioinorganic metalloenzymes. It is of interest to immobilize these ligand chelates onto heterogeneous supports. This, however, requires the use of bromine-substituted (chloromethyl)pyridines, whose current synthetic routes involve the use of extremely pyrophoric chemicals, such as n-butyllithium that require cryogenic reaction conditions, and toxic chemicals, such as thionyl chloride, that are challenging to handle and require extensive hazard controls. Herein, we report alternative methodologies towards the syntheses of 2-bromo-6-hydroxymethylpyridine and 2-bromo-6-chloromethylpyridine from inexpensive commercially available 2,6-dibromopyridine using isopropylmagnesium chloride lithium chloride complex (Turbo Grignard) and cyanuric chloride which are easier to handle and require milder reaction conditions than the conventional reagents. Gas chromatography-mass spectrometry (GC-MS) methods were developed and simple 1H- and 13C- nuclear magnetic resonance (NMR) and Fourier-transform infrared (FT-IR) spectroscopies were also used to monitor the conversion of both reaction steps and showed that products could be obtained and isolated through simple workups without the presence of unreacted starting material or undesired overchlorinated 2-chloro-6-chloromethylpyridine side product.


Using the incremental plastic damage theory and the phenomenological model for predicting fatigue crack growth in fiber reinforced metal laminates,a predicting model of fatigue crack growth in fiber reinforced aluminium alloy laminates under tension-compressive loading was deduced.The experiments of the fatigue crack growth in the glass fiber reinforced aluminium alloy laminates at the R=-1 and R=-2 were performed in order to verify the predicting model.The results show that the two cases of the effect of compression loading are pointed out that when the effective stress ratio RC0,it is characterized by counteracting the residual stress in the aluminium alloy layer,and when RC0,it is characterized by causing the plastic damage in the aluminium alloy layer and the promoting effect on the fatigue crack growth in fiber reinforced aluminium alloy laminates.The effect of compression loading should not be neglected.The model has been obtained good agreements with the experimental data.


Abstract The discovery of a fourth member of the opioid receptor family, opioid receptor-like (ORL-1) recptor in 1994 gave rise to a new camp in opioid research, since this new G-protein coupled receptor though being in logically homogenous to classical opioid receptors' did not bind opiates with high affinity. A year later, two groups independently identified the endogenous ligand of this receptor, a 17 amino acid neuropeptide named nociceptin or orphanin FQ. This receptor family was officially renamed after its endogenous ligand as nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) receptor in IUPHAR2002. The NOP receptor and N/OFQ are widely distributed in the central nervous system (CNS), and the periphery. Several studies have implicated the N/OFQ-NOP receptor plays an important role system in pain, anxiety, learning, memory, food intake, diuresis, and drug addition. However, N/OFQ modulation of pain pathways is yet to be completely understood. N/OFQ, unlike traditional opioids which display analgesia effect, elicited both analgesia and hyperalgesia. It has great benefit in understanding the physiological role(s) of N/OFQ in pain regulation by developing NOP receptor ligands, including agonists and antagonists. A novel ligand for the receptor (NOP), [(pF)Phe4, Arg14, Lys15] N/OFQ-NH2 (UFP-102), has been generated by combining in the N/OFQ-NH2 sequence two chemical modifications, [Arg14, Lys15] and [(pF)Phe4], that have been previously demonstrated to increase potency and ability lasting, respectively. The present study, quantitatively investigated the potency of UFP-102 at NOP receptors of rat brain slices containing the midbrain ventrolateral periaquaductal gray (vlPAG), a crucial site for N/OFQ-induced reversal of opioid algesia, using the blind patch-clamp whole cell recording technique. UFP-102 concentration-dependently induced an outward current at resting membrane potential and increased the membrane current elicited by hyperpolarization ramps from -60 to -140 mV in ventrolateral PAG neurons. The current induced by UFP-102 is characterized with inward rectification and has reversal potential near the equilibrium potential of K+ ions according to the Nernst equation. Therefore, UFP-102 activates inwardly rectifying K+ channels. UFP-102 showed similar maximal effects (35 ± 3% and 40 ± 4%, respectively) but higher potency (4- to 5-fold) relative to N/OFQ. UFP-101, a novel selective and competitive antagonist of NOP receptors, concentration-dependently attenuated of K+ current induced by UFP-102 but did not change its reversal potential. It produced a parallel right-shift of the concentration-response curve of UFP-102 but did not alter the extent of UFP-102 induced maximal response. The antagonistic effect of UFP-101 on UFP-102 induced K+ current was surmountable by increasing the UFP-102 concentrations. However, the nonselective opioid receptor antagonist, naloxone, did not attenuated of K+ current induced by UFP-102. The pIC50 of UFP-101 against UFP-102 was 6.52. It is concluded that, in ventrolateral PAG, (1) UFP-102 is a selective agonist of NOP receptor with an EC50 value of 11±2 nM. (2) UFP-102 showed similar maximal effects but higher potency (about 4- to 5-fold) relative to N/OFQ.


A concept "Estimation of personnel" is considered in the article, the criteria of estimation of personnel are exposed, the
system of estimation of personnel is described, the traditional and modern methods of estimation of personnel are analysed.
The problem of introduction of modern methods of estimation of personnel is studied on the Ukrainian enterprises, the methods
of its permission are offered.


This article discusses the implications of the Internet for lean production systems in the automotive supplier industry. The effects on supply chains, production scheduling, inventory control, supply design involvement, and the workforce are some of the issues addressed. Results from a survey of automotive suppliers located in the Spanish region of Aragon, show the use of the Internet in the supply chain management, their advantages and limits, and its relationship with lean performance indicators.


The goal of this book is to provide managers with a decision -making framework for planning, designing, and promoting public transportation - particularly in a time of limited resources. The purpose is to provide planners, analysts, managers, and transit board members with a strategic approach on operating a transit system with a consumer orientation. The focus centers on transit operations in the United States, but examples and insights are used from other countries as well.


For pt.I see J. Phys. C., vol.17, p.5049, 1984. The author extends the previous calculation on a dynamical mean-field theory of realistic spin glasses (Chowdhury and Mookerjee) so as to incorporate the effect of the reaction field. The 'ordering temperature' of a mode is shown to depend not only on the corresponding eigenvalue of the random matrix J but also on the structure of the whole spectrum.


The throughput of unbuffered shuffle-exchange networks (also known as delta networks) is related to the arrival rate by a quadratic recurrence relation. Lower and upper bounds on the solution of this recurrence relation are derived in this paper. Two approaches for improving the throughput of unbuffered delta networks are investigated. The first approach combines multiple delta subnetworks of size N × N each, in parallel, to obtain a network of size N × N. Three policies used to distribute the incoming packets between the subnetworks are discussed and the relative effect of each on the throughput is compared. The second approach replaces each link of the simple delta networks by K parallel links (K equals 2,4,...,). The throughput of such networks is analyzed and one possible implementation for crossbar switches that could be used in these networks is discussed. The throughput of such networks with four parallel links is almost equal to the throughput of crossbars.


The goal is to create a model of operational monitoring and diagnosing information systems data. To achieve this goal, you need the initial separation of the object model on digital and analog, with further "combination" on the parameters of the digital output channel and the analog output of the modem.


It's hard enough learning a new subject even when it's only a single acronym. Indeed, if you have recently begun looking at the issue of managing digital assets, you will encounter a blizzard of terminology and acronyms on data storage, networking, analog-to-digital capture and encoding, metadata, indexing and distribution. The other important consideration here is the business case for using such technology, and adopting processes and workflows that will maximize such an investment.


Liberalism and Economic Order is Hayak's representative work.From the angle of philosophy,the essay analyzes Hayak's economic liberalism and his conclusions by the theory of knowledge distribution.His new visual angle is beneficial to improve our thinking methods.And his analysis on the planned economy is also significant to develop the socialist market economy.


Boserup's intensification model of the late 1960s (Boserup 1965), on which much of the current debate on agronomic change still rests, postulated that rising population pressure over a fixed land area results in progressive agricultural intensification and the adoption of new technologies as people attempt to raise agricultural production. The model maps a unilinear sequence of agricultural change as people move from less to more intensive agricultural practices to achieve higher production. In this process, labour use increases and efficiency falls as labour is substituted for land.


Abstract Introduction The COVID19 pandemic has led to anxiety and fears for the general public. People were concerned about coming to a medical facility where the virus might be transmitted. Furthermore, stay-at-home orders that were implemented during the pandemic did not apply to clinic visits but contributed to people staying at home even for medical care. We hypothesized that there were delays in burn care due to the pandemic. Methods We queried our clinic data for number of clinic visits and new burn evaluations by month. Patients referred to our clinic from March 15, 2020 to Sept 15, 2020 were reviewed for time of presentation after injury. Days from injury date to clinic referral date and days from clinic referral date to appointment date were calculated. Patients who were referred but did not show and were not seen in our ED were not included because injury date could not be determined. Univariate analysis was performed. Results As seen in Figure 1, our in-person clinic volume decreased in April and May 2020 but rebounded in June 2020 as compared to the number of clinic visits for the same months last year. Similarly, in Figure 2, our new burn evaluations decreased in April and May 2020 compared to our new burn volume from 2019. However, our video telehealth visits increased in March and April then decreased in June-August. Conclusions Our burn clinic remained open to see patients with burn injury throughout the pandemic, however, clinic visits were delayed early in the pandemic. While we had an increase in video telehealth, it does not account for the decrease in clinic visits. This may be due to low enrollment in the electronic medical record encrypted communication platform and/or limited knowledge/access to the technology. Additional care may have been informally given via telephone but not well captured. Furthermore, burn care was delivered in the following months. Additional investigation is necessary to see if the incidence of burn injury decreased.


Osteoradionecrosis (ORN) of facial skeleton has been defined as a necrosis or death of the bone of the mandible or maxilla that may occur following radiation therapy for cancer in the oral and perioral region.1 It is known to occur when jaw bones are directly in the field of radiation. The reported incidence ranges lrom 2.6% t0 22% but most commonly considered to be around 10% + 5%. Diagnosis of ORN depends primarily on clinical and radiographic changes in the bone. The signs and symptoms typically include ulceration of the mucosa, loosening of the teeth, exposure of the necrotic bone; and rarely pain is a significant component.2


This issue of Commonwealth Trade Hot Topics examines the potential implications of the Paris Agreement from the 21st Conference of the Parties of the United Nations Framework Convention on Climate Change (UNFCCC) for trade and investment policy for Commonwealth member countries. It also explores more broadly how governments might support a mutually reinforcing relationship between the trade and environment regimes.


This study investigated the relationship between a set of people performance enablers and psychological attachment behavioural states in a variety of South African work settings. The sample (N = 582) comprised mostly males (69%) and black Africans from organisations in the manufacturing (17%), financial services (14%), information technology (16%) and the non-profit sectors (53%). Data on employees' perceptions of performance enablers and their psychological attachment to the particular organisation were collected using the Psychological Work Immersion Scale (PWIS: Veldsman, 2013). The data were analysed using confirmatory factor analysis to reveal the structure of the people enablers and psychological attachment variables in the South African work settings. Structural equation modelling was used to predict psychological attachment from the performance enabler indicators. The findings provided evidence that employees' perceptions of performance enablers significantly explain their level of psychological attachment (commitment, motivation and work absorption). Manager credibility appears as a key performance enabler and commitment as a strong element of psychological attachment. The research contributes to the literature on individual and organisational performance by extending research on work psychology in the South African context.


In this work, the characteristics radiopropagation of wireless systems within complex indoor scenarios is presented. An analysis of the physical radio channel propagation inside different complex indoor scenarios is presented based on three-dimensional ray launching in house code. The influence of topology as well as morphology of complex indoor scenarios in the deployment of wireless sensor networks and wireless systems is analyzed. The use of adequate radioplanning strategies lead to optimal wireless network deployments in terms of capacity, quality of service, and reduced power consumption.


An analytical program for reinforced concrete frame subjected to high temperature is proposed in this paper,which is based on three dimensional transient thermal field and two dimensional finite element mechanical model.The reliability of the program is validated using the test results provided by former researchers.A three-span one-storey reinforced concrete midframe is selected for fire response analysis,different line stiffness ratios of beam to column and different axial load ratios of column are considered in the analysis.Based on simulation results,the variation of deformations at some key points in the frame with time is discussed.


This paper reviews our research progresses of hydrogenated amorphous silicon (a-Si:H) and microcrystalline (μc-Si:H) based thin film solar cells. It coves the three areas of high efficiency, low cost process, and large-area proto-type multi-chamber system design and solar module deposition. With an innovative VHF power profiling technique, we have effectively controlled the crystalline evolution and made uniform μc-Si:H materials along the growth direction, which was used as the intrinsic layers of pin solar cells. We attained a 9.36% efficiency with a μc-Si:H single-junction cell structure. We have successfully resolved the cross-contamination issue in a single-chamber system and demonstrated the feasibility of using single-chamber process for manufacturing. We designed and built a large-area multi-chamber VHF system, which is used for depositing a-Si:H/μc-Si:H micromorph tandem modules on 0.79-m 2 glass substrates. Preliminary module efficiency has exceeded 8%.


The paper studies the concept of logistics,points out that logistics consists of 3PL,4PL,reverse logistics and green logistics etc.studies the following logistics as E-commerce and logistics management,GIS,intelegent transportation system,digital warehouse and barcodes and gives out how to control logistics costs.


C ARBOHYDRATES and hydrocarbons are the prime sources of life everywhere. Without the energies locked in these compounds and their chemical derivatives, there is no life. To translate these technical terms into plain language, they mean food and fuel in their various forms. The more modernised a society becomes, the larger in volume and the more varied in quality anid composition are these basic ingredients of life, and the greater is the society's preoccupation with securing their ready supply. China is a case in point. Consciously or subconsciously, its leaders have recognised these facts by electing Tachai, the advanced agricultural commune, and Taching, the first major source of liquid energy, to serve as models in all spheres of development. For more than a decade, these two enterprises have been chosen as signposts to what modern China stands for. Tachai and Taching have also served as ideological symbols and as issues of practical politics. Where society is stagnant, the volume and composition of food and fuel can be treated as static. No such position exists where the population exceeds its resources, and where its growth exceeds past precedent. Here the search is on for ever new sources of carbohydrates and hydrocarbons and thus for the solution of exist'ing food and fuel problems. This is as true of the post-Mao era as it was during the lifetime of the great helmsman, even if the political language in which 'the issues are to be presented in future undergoes certain verbal changes.


Infrastructure projects provide a spatial fix by increasing the scale and rate of capital accumulation, and because infrastructure projects themselves absorb massive amounts of productive and finance capital. I seek to explain the timing, character, and consequences of a Can $85 billion infrastructure boom in Canada's largest province, Ontario, between 2003 until 2013. I focus on the expansion and privatization of environmentally oriented infrastructure in Ontario via three policies: the conversion of public coal power plants to private natural gas and nuclear facilities; the Green Energy Act (a renewable energy feed-in tariffs programme); and The Big Move (a Can $50 billion dollar rapid transit plan using a public–private partnership model). I employ a Polanyian– O'Connor approach to emphasize the role of labour, environmental groups, and other social movement groups in bringing these investments about. I argue that infrastructure investments are not only a spatial fix aimed at finding capital a safe long-term investment and addressing class struggles around job creation. In Ontario these infrastructure investments have also provided the state with a broader socioecological fix for the economic and political contradictions stemming from air pollution and congestion. Social movements have pressured the government to address what James O'Connor refers to as the underproduction of the conditions of production: that is, degraded human health and quality of life; a deteriorating environment; and inadequate public infrastructure. Throughout the paper I emphasize how the socioecological fix in Ontario is being accomplished by advancing the neoliberal governance of public infrastructure. I point to how these neoliberal socioecological fixes are simply displacing socioecological crises to new spatial and temporal scales.


— Genetic algorithm is widely used in optimization problems for its excellent global search capabilities and highly parallel processing capabilities; but, it converges prematurely and has a poor local optimization capability in actual operation. Simulated annealing algorithm can avoid the search process falling into local optimum. A hybrid genetic algorithm based on simulated annealing is designed by combining the advantages of genetic algorithm and simulated annealing algorithm. The numerical experiment represents the hybrid genetic algorithm can be applied to solve the function optimization problems efficiently.


The passenger corridor of the Shanghai Pudong International Airport has been adopted with a steel roof truss and a space stayed cable structure system. The stayed cable groups have been stretched seperately in four batches.The correction of geometrical deviations bave been done and made by allocation and modification of stretching forces of the group cable. Through calculation and comparison course of stretching procedures could be ascertained. During prior construction there is an analogy construction has been carried out and implemented with tri-vector computer analytical technology. It has proved that the results are consistent with practical condition.And besides,the evidence of application of computer technology bas been proved a perfect success.


This paper presents design principles of a low-power and portable bioelectrical impedance analyzer. Based on the low-power and portable notion, It uses a low-power computer as the core, adopting MSP430F149 chip as the processor and utilizing AD5933 which is launched by Analog Devices and is highly integrated to measure and collect the multi-frequency impedance information. And then these data will be sent to the control system on PC through its own serial interface, displayed in the man-machine interactive interface on PC.


The aim of this paper is to summarize the current state of understanding the smart city concept and to present a proposed communication platform for the development of city services particularly in developing countries/Amman city as a case study area .The paper shall present introduction to give an overview of various aspects city services, smart infrastructure and facilities, using information and communication technologies, interconnection, feedback, and electronic and digital applications. The next part addresses individual challenges for the planning, development, and operation of cities. New solutions allow for use of different data on Amman city and meet the request for better city services. An overview of smart cities applications and services is given in the next section of the paper. An overview of some aspects related to the technological solution of services is discussed in the summary section.


Objective: The present report is an investigation of anti seizure activity of Mussaenda frondosa in male Wistar albino rats by using Cobalt induced Epilepsy. Method: The MEMF at doses of 200 and 400mg/kg, p.o and the standard drug Silymarin (100mg/kg, p.o) were administered three times at 12h intervals and then Cobalt (1ml/kg) was administered to all the groups except normal control for 2 days. The antiseizure activity was assessed by using various biochemical parameters histopathological studies were observed after 36h of Cobalt treatment. Results and Discussion: The MEMF at the doses of 200 and 400mg/kg inhibited Cobalt induced brain toxicityin Wistar albino rats as assessed by the biochemical changes and histopathological studies. Conclusion: The methanolic extract of aerial parts of Mussaenda frondosaafforded significant protection against Cobalt-induced epileptogenic cortoxy injury.


The utility model provides a hoisting machinery health monitoring system based on wireless sensing nodes. The hoisting machinery health monitoring system based on wireless sensing nodes comprises more than one sensor acquisition system and a data acquisition network gateway, wherein each sensor acquisition system is in wireless connection with the data acquisition network gateway. The hoisting machinery health monitoring system based on wireless sensing nodes can monitor a health state of hoisting machinery in real time, and noise interference caused by long cable transmission is eliminated by employing a wireless transmission mode, and monitoring precision and capacity of interference resistance of the monitoring system are improved.


The rheological properties of chitosan and the factors such as degree of deacetylation, concentrations, pH, electrolyte, pepsin, temperature and different properties of drug were investigated. The results showed that chitosan exhibited pseudoplastic construction and non thixotropy appeared in the solutions, and its concentration had most obvious effect on the rheological properties.


It becomes an increasing important task to discover desirable information from tremendous web resources,and therefore the more accurately the focused crawler describes the users' interested topics,the more useful the information obtained by it will be.However,the neglect of context leads traditional approaches to the failure of achieving this goal.In order to overcome this shortcoming,a new context-sensitive topic description method based on ODP(Open Directory Project) is proposed in this paper.First of all,the best topic feature subset is determined by a new feature selection algorithm.And then,we optimize the topic description method to improve the performance by utilizing topic context.The experimental results show that this new approach extracts the features effectively with a better performance in both the precision and the sum of information while minimizing its dimension size significantly.


Abstract : The US military is strong in battle but weak in influence. Because wars of survival are the reason for the military's existence, the military must be able to do what only the military can do apply force. In wars of choice, however, the application of force and its poor utility in achieving political outcomes has been a problem for the US military. National character constrains the US military to persuade conflict populations without force. As the military increasingly takes direct responsibility for achieving political goals without force, the ability to influence foreign audiences becomes more important. This monograph describes the benefit for the operational commander of clearly communicating a narrative to the conflict population that accounts for culture and aligns with the US government's explicit reasons for military involvement. The case studies of the Philippine War and the Vietnam War show the plausibility of the hypothesis while cautioning against looking to the operational narrative as a panacea. It is impossible to appeal to every audience, be understood all the time, and always effect behavior change in target audiences. However, to communicate the operational commander's vision is better than letting the adversary win the conflict of narratives by default.


A new ICP-MS system was used for successful determination of REE, Th, and U at ultratrace level concentrations in ultramafic rocks. Typical concentrations for these elements in the analyzed samples were found to vary between 0.01 and 1 μg/g in the solid rock material. The samples were digested using acid sample treatment in a conventional microwave oven. Accuracy and precision of the described method were tested with international standard reference materials Serpentine (UB-N) and Anorthosite (AN-G). Stability of the instrument was investigated in clean as well as in synthetic rock solution (500 mg/L Fe, Mg, and Ca) over a period of 2 h using a 100-ng/L multielement standard solution. Detection limits were calculated from 10 measurements of the acid blank and the intensities of 100 ng/L standard solution in the synthetic rock matrix, which vary between 0.12 and 0.62 ng/L


Ross's underlying performative can now be reinterpreted in terms of Cinque's adverbial MoodevidentialP. The `default' interpretation of MoodevidentialP, in the absence of other indications, is that the speaker (source of information) assumes responsibility (evidence type) for a sentence uttered (Cinque, 1999). This speaker can be represented by a 1st person feature in the Moodevidential° of main clauses. Such a formalization immediately evokes a host of questions with respect to the representation of MoodevidentialP in complementation, more in particular in direct and indirect speech. Such a discussion is important here in view of the evident relationship between direct speech and the evidential category of quotative. Reinterpreting ideas of Ban®eld (1982), I would like to propose that the person features which function as `Source of information' in Moodevidential° differ considerably in direct and indirect speech. The data in (43a,b) suggest that the person features in Moodevidential° of indirect speech are anaphoric in nature: they take the matrix subject as the `Source of information'. This analysis also re ects the idea that the matrix subject is responsible for the information status of the sentential complement. This does not mean that the matrix subject is necessarily responsible for the degree of reliability with which the sentential complement is presented. With verbs of saying and believing, the degree of reliability covaries with the reliability of the matrix subject, but with factive verbs, the degree of reliability of the sentential complement is entirely independent of the reliability of the matrix subject, and is presented as a fact. In direct speech complements, the person feature functioning as `Source of information' in Moodevidential° could be argued to be identical to that in main clauses, i.e. 1st person. A comparison of direct speech in (45) with the sentences in (43) shows that the `point of view' adjunct as for my/himself in (45) patterns with main clauses, not with embedded clauses:


Facile synthesis of biologically active N-alkyl and N-acyl carbazole derivatives under mild conditions is described. The compounds were synthesized by reacting polymer-supported carbazolyl anion with alkyl and acyl chlorides, respectively. Furthermore, dimeric products containing alkylene and diketo alkylene bridges were also achieved by reacting polymer- supported carbazolyl anion with α,ω-dibromoalkanes and acid dichlorides, respectively.


Machine learning can play a significant role in bringing new insights in GNSS remote sensing for ionosphere monitoring and modeling to service. In this paper, a set of multilayer architectures of neural networks is proposed and considered, including both neural networks based on LSTM and GRU, and temporal convolutional networks. The set of methods included 10 architectures: TCN, modified LSTM-/GRU-based deep networks, including bidirectional ones, and BiTCN. The comparison of TEC forecasting accuracy is performed between individual architectures, as well as their bidirectional modifications, by means of MAE, MAPE, and RMSE estimates. The F10.7, 10 Kp, Np, Vsw, and Dst indices are used as predictors. The results are presented for the reference station Juliusruh, three stations along the meridian 30°E (Murmansk, Moscow, and Nicosia), and three years of different levels of solar activity (2015, 2020, and 2022). The MAE and RMSE values depend on the station latitude, following the solar activity. The conventional LSTM and GRU networks with the proposed modifications and the TCN provide results at the same level of accuracy. The use of bidirectional neural networks significantly improves forecast accuracy for all the architectures and all stations. The best results are provided by the BiTCN architecture, with MAE values less than 0.3 TECU, RMSE less than 0.6 TECU, and MAPE less than 5%.


Through the analysis of the common faults in the construction of drilled poured in place pile the paper combined with the actual project proposes some effective measure. Those faults contain water seepage of pile, interlay of pile body, deviation of elevation of pile top, break of the pile and so on. Those effective measures have certain direct significance for the construction of poured in place pile and the construction quality's guarantee.


Travelling through the foothills of the Pyrenees, the episcopal visitor Guerau Caluet arrived in the parish of Sant Martí de la Vajol on an autumn day in 1314. As in so many parishes visited on his journey, the visitor found that the rector Berenguer kept a concubine, and in this case, was also known to celebrate mass with his grandson and young son. This was not, however, the only blatant violation of canon law and synodal statutes. Berenguer testified that one day in May the sacrist Bernat, from the suffragan church of Agullana, had called on him to deliver the mass for the burial of a female parishioner. The rector recounted that while reciting the gospel for the funeral, he was in need of hosts and was unable to proceed with the mass "until Guillema, the concubine of the sacrist, sent the key to the sacristy where the hosts were." As it happened, the priest Bernat was out of town and he had entrusted the sacristy keys not to his colleague Berenguer, but to his concubine.


In the crystal structure of the methanol-coordinated mononuclear title compound, [Fe(C13H11N2O)Cl2(CH4O)], the FeIII atom is six-coordinate in an octahedral environment and the Cl atoms are cis to each other. Hydrogen bonds between the hydroxyl group of the methanol ligand and the Cl atom of an adjacent molecule lead to the formation of a chain that runs along the b axis of the orthorhombic unit cell.


mate of 90%; these are statistically close enough, given the differences in our methods and the systems we analyzed, to strongly suggest the true rate is in the vicinity ofperhaps 75% to 95%. With regard to associated reductions in cost, these will vary from place to place, and our estimate for Los Angeles cannot be automatically extrapolated to other environments with different configurations to their prehospital systems. As we noted in our discussion, we think a system that relies primarily on off-line medical control (which is very different from a "discretionary system") offers tremendous potential advantages, including, ultimately, closer and more reliable supervision ofparamedics than on-line systems. This does require, of course, as Davidson and Erder agree, a carefully constructed computer-based method of identifying any paramedic deviation from protocol.


The present invention relates to substituted N-benzo [d] isoxazol-3-yl-amine derivatives, processes for their preparation, pharmaceutical compositions containing these compounds, and the use of these compounds for producing medicaments.


An 18-year-old female was admitted because of dyspnea at rest. A chest computed tomography (CT) scan and fiberoptic bronchoscopy demonstrated a polypoid tumor in the left main bronchus, 0.5cm distal from the carina. Surgical resection of the tumor was performed, along with. A pathological evaluation and the immunohistochemical findings led to the diagnosis of a glomus tumor, which originated from the bronchus, an area where this type of tumor has rarely been reported.


The authors in this special issue section entitled "Spirituality in Social Service: Micro, Mezzo, and Macro Issues and Interventions —Part II" focus on the significance of spiritual concerns with a range of social work clients. The five articles that comprise this special issue section include the following themes: community violence resulting in complex trauma for adolescents; compassion fatigue and compassion satisfaction among clergy; spirituality and type 2 diabetes among African Americans in the Arkansas Delta; social support associated with general well-being of Korean immigrant elders; and spirituality and strengths-based spirituality related to substance abuse treatment. The multidimensional aspects of social work with the five populations addressed in this special issue will benefit from a sensitive holistic approach that includes the micro, mezzo, and macro levels of practice. A constitutive element of spirituality involves the meaning making function of humans. Making sense out of our world and the events we encounter grounds us in our reality, provides us with a world view based on our interpretation of life experiences, and is the foundation upon which we build strengths in order to improve our lives. The central process of meaning making in relationship to traumatic events is a key factor in intervention planning. There are a growing number of therapeutic approaches to rapidly address the effects of traumatic events with individuals. The growing number of contemporary events that involve trauma will continue to involve the development of new and innovative approaches


The tendencies obvious today in robot construction relate to flexible automation and mechatronics, i.e. increasing their intelligence level to compensate for nonlinearities and to adapt to distortions. The applied research programme developed by the authors was directed towards optimizing the static and dynamic performance of the linear hydraulic motors with the purpose of investigating nonlinear phenomena occurring while in operation and towards producing a package of numerical simulation software that provide useful information to their design to make them operate at the level of performance that is today required.


The article is devoted to identifying key differences between Ukrainian and Russian political identities. It is ascertained that the basic parameters for Ukrainian political identity are individualism, rejection of the authoritarian principle, love of freedom, etc. The idea of freedom has been long embedded in the mentality of Ukrainian people. By contrast, as regards the Russian people (Muscovites) mentality, slavish obedience has long been considered a virtue. According to eyewitnesses, Muscovites considered deception to be a proof of great intelligence. They are not ashamed of lying.
Ukrainian political identity representatives should not be expected to automatically submit to the authorities, as the reputation and legitimacy of the leader are important for them. Ukrainians can force an illegitimate official who is also acting illegally to relinquish the power.
The bearers of Russia's political identity are dominated by the need for a supreme leader who will make all important decisions on his own. This state of Russian political culture, where decision-making is delegated only to rulers, and the role of the population is to implement these decisions, is determined by long-standing practices of authoritarianism. Atomization, that is, the disunity of society, is one of the dominant features of Russia's political identity nowadays. Due to the atomization of society and people being unable to trust each other, all sorts of significant protests or rallies in Russia are impossible.


Does top management matter? This question is investigated by identifying two types of leadership succession (insider and outsider) and two organizational situations (decline and prosperous). Results suggest that leadership origin influences hiring decisions, but has no impact on profitability.


A series of recognition methods of characters are described, in which the modern recognition methods based on structure and statistics are compared and analyzed. Aiming at present immature method of offline recognition, the characteristics of handwritten characters and the differences between recognition methods of handwritten and printing characters are studied. Then the affecting factors as noise etc. to the recognition of handwritten characters are investigated. Eventually, the personal viewpoint to the research direction of this field was forecasted.


A highly diastereoselective synthesis of tetralin-fused spirooxindole derivatives was described. Treatment of benzylidene oxindoles with a catalytic amount of Sc(OTf)3 in refluxing hexane afforded the target compounds in good chemical yields with excellent diastereoselectivities (up to >20:1). Detailed investigation of the reaction mechanism revealed that both interconversion of the two diastereomers and their solubility difference in reaction medium were the key to achieving excellent diastereoselectivities.


Many symptoms were derived from the vibration faults of a steam turbine set and summarized into a knowledge store house of expert system, and the expert system of multi-symptom fuzzy diagnosis of the vibration faults of a steam turbine set was founded by taking the fuzzy equation founded using the fuzzy theory as an inference rule. The expert system was inspected through practical application and the results were satisfactory.


SLEEP PROBLEMS ARE RELATIVELY COMMON AMONG OLDER PERSONS, ALTHOUGH SPECIFIC PREVALENCES VARY ACCORDING TO THE ASSESSMENT CRITERIA EMPLOYED. The prevalence of primary insomnia (requiring symptoms of sleep complaints impairing functioning for at least a month and not exclusively occurring as a result of other sleep problems, mental disorders, substance abuse, or general medical conditions) is estimated at 6% for all adults according to the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition.1 While concurring with this 6% figure for primary insomnia, Ohayon's 2002 review2 of more than 50 community studies found that about one third of adult respondents reported at least 1 sleep complaint or sleep problem, such as difficulty getting to sleep, difficulty maintaining sleep, or early morning awakening. Most studies indicate that the prevalence of sleep problems increases with age and is higher for women than for men.2-4 For example, a large longitudinal Swedish study reported that the frequency of sleep problems for women increased by about 30% between ages 38 and 84 years, and an Italian study of older community-dwelling persons found that 54% of the women, compared with only 36% of the men, reported sleep problems.56 Morgan's 1992 review of 6 studies involving older persons concluded that 20% to 40% of older persons living at home experience disturbed or poor-quality sleep.7 There is some evidence, however, that the type of sleep problem changes with age. Younger adults may have more difficulty falling asleep while older persons may have more difficulty staying asleep.1 Regardless of age or sex differences, sleep problems have been linked with a variety of negative health outcomes in both cross-sectional and longitudinal studies. Such outcomes include self-rated health, depression, pain, physical disability, cognitive decline, emotional role limitations, falling, and all 8 components of the SF-36.8-13 Stoller has estimated that, because of lost productivity, sleep problems cost the United States economy more than $100 billion dollars every year.14 Causal order is not always clear, however, because of the limited number of longitudinal analyses and the close relationship between sleep problems and coexisting pain and disease.15 In spite of uncertainties in research findings, it does appear reasonable to conclude that sleep problems are relatively common in old age and are associated with negative health outcomes. If one's own sleep problems have negative outcomes for oneself, what about those of one's spouse? To what extent do spouses' sleep problems impact the health and well-being of a partner? There is surprisingly little information on this question. Although not strictly an area involving sleep problems, there is some evidence that mismatched couples in terms of sleep-wake patterns (one an evening person, the other a morning person) experience poorer marital adjustment than do those who are matched (both morning persons or both evening).16,17 There have also been spouse studies of 2 specific types of sleep problems—apnea and snoring. Cartwright and Knight18 interviewed 10 wives of men with sleep apnea and scored them as showing poor adjustment in 2 phases of the Marital Satisfaction Inventory—marital and social-leisure areas. Ulfberg and colleagues19 compared wives of heavy snorers with those of nonsnorers and found more frequent reports of insomnia, morning headache, daytime sleepiness, and fatigue among the former. Three published studies have evaluated improved sleep quality and quality of life in partners of patients with sleep apnea who are undergoing continuous positive airway pressure (CPAP) therapy. In one, the sleep quality of partners was found to improve when their spouses began receiving CPAP therapy.20 In another study that compared sleep quality and quality of life of partners whose spouses had completed 1 month of CPAP therapy with those whose spouses were treated with placebo, there was no difference in the partners' objective sleep quality or quality of life, but the partners in the treatment group did have a higher subjective sleep quality. 21 The broadest results were reported by Parish and Lyng in a 6-week before-and-after trial of 54 partners whose spouses were receiving CPAP therapy. Partners showed improved quality of life on a range of domains as measured by the SF-36 and the Calgary Sleep


In environments with photocopiers, among the monitored contaminants, there are the volatile organic compounds (VOCs), aromatic polycyclic hydrocarbons, aldehydes, ketones, ozone, and particles. The present study aimed at the assessment of the genotoxicity of the air in environments with photocopiers. Six clones of Tradescantia (4430) had been kept for 15 days in two environments – one of them with four photocopiers working 12 hours per day, and the other with three photocopiers working 8 hours per day. Other six plants comprised the check group and were kept in greenhouse. The frequency of genic and chromosomal mutations was determined through the assessment of the stamen hair cells, and tetrads, respectively, performed 15 days after the exposition. There were quantified 415 stamen hairs and 1,500 tetrads per treatment. The plants from treatment 1 – exposed to daily cycles of 12 hours with 4 photocopiers – have presented the highest frequency of chromosomal damage with significant differences in relation to the check group (p


Objective:To investigate the comprehensive intervention of oncology,psychology and sociomedicine to improve the quality of life(QOL) of patients with breast cancer. Method: One hundred and three patients were randomly divided into intervention group(49 people) and control group(54 people). The health intervention included systemized anti-cancer intervention directed by specialists and the masses anti-cancer intervention, but the control group was in spontaneous convalescence state. The intervention duration lasted 2 years. The QOL of survival patients was estimated by the modified EORTC-QLQ-C30 before or after intervention. The scale measured somatic function, mental status, social-famil function,general symptom-side reaction,special symptom-side reaction and self-evaluation in six dimension. The variation of QOL was analyzed by the covariance.Result: The D-values of both groups before or after intervention were compared. The D-values of somatic function,mental status,self-evaluation were 4.17±1.87?5.69±4.81?1.72±0.88 respectively in intervention group after the time effects were controlled, its′ increased degree was higher than those in control group(P0.05 or P0.01). The D-values of somatic function, mental status,symptom-side reaction,self-evaluation were 2.546±0.542,5.760±1.276?3.580±2.490?2.028±0.355 respectively,in intervention group after the disproportion factors were controlled, its′ increased degree was higher than those in control group(P0.05 or P0.01). Conclusion:The multidisciplinary comprehensive intervention is helpful to elevate the QOL of patients with breast cancer.


Diaqua(dipicolinato)oxovanadium (IV) ethanol solvate crystallizes in the triclinic space group P1. The complex was characterized by FTIR, elemental analysis, thermal gravimetric analysis, and solution visible spectral analysis. The complex alone cleaved DNA in the absence of hydrogen peroxide and its nucleolytic efficiency is greater than that of VOSO4. Its nucleolytic efficiency is affected by the choice of buffer used and pH. DNA cleavage can be inhibited by DMSO, NaN3 and catalase, implying involvement of ROS. An MTT assay, involving the lung cancer cell line PC9, gave IC50 values of 9.5 ?M and 16 ?M for the complex and VOSO4 respectively. For breast cancer cell line MCF-7, this complex is less cytotoxic, with an IC50 of 16 ?M.


The formation of chromospheric resonance line profiles is examined for the case of the relatively low-density atmospheres appropriate to late-type supergiants. The effects of partial frequency redistribution control the emergent line profiles, to the extent that even an isothermal atmosphere can give rise to apparent emission features. Schematic model chromospheres are used to demonstrate the effects of different velocity fields and temperature-density structures on the line profiles, as a first step toward a clearer understanding of the chromospheric line profiles and why supergiants have broad emission lines (the Wilson-Bappu effect). Neither the Doppler nor the mass column density explanation alone can explain the Wilson-Bappu effect in supergiants, but both theories may play a role.


The adsorption rate of three organophosphorus pesticides: diazinon, azinphosmethyl and fenthion by F-400 activated carbon has been studied by using a combined flow injection analysis-high performance liquid chromatographic system. Results showed a first-order kinetics. The slope of the straight lines has been related to a pesticide removal efficiency factor. The values of this factor indicate that this methodology is suitable for removing diazinon, azinphos methyl and fenthion from wastewater. On the other hand, no reactions have been observed on the activated carbon surface, thus physical forces seem to be the cause of the adsorption


The adaptive nature of clonal growth rules was studied using a Monte Carlo simulation based on a stochastic, spatially explicit growth model. In this model, the development of a clone was controlled by environment-dependent growth rules, acting upon elementary developmental decisions, such as suppression or activation of meristems at certain locations, or modification of internode length. The neutral model, used as a control, simulated a plant of rigid, non-environment-dependent form. Growth proceeded in a spatially and temporally heterogeneous environment. A wide range of environmental types - modelled as mosaics of resource-rich and resource-poor sites - were used for the tests, and analysed in the framework of an information theory model (...)


In this paper, we discuss a case study in the use of virtual reality (VR) as a tool for actors during the rehearsal process. A treatment group of actors was permitted to explore and practice their ...


Abstract An experimental model of a hard-disc system (the two-dimensional analogue of a hard-sphere system) is described. The melting transition is studied qualitatively by a photographic technique. The half-width of the singlet distribution function is measured and compared with results obtained by the method of molecular dynamics. Images of the pair distribution function are presented.


Review(s) of: Children in the New Media Landscape: Games, Pornography, Perceptions, by von Felitzen, Cecilia and Carlsson, Ulla, UNESCO Clearinghouse on Children and Violence on the Screen, Goteborg, 2000, ISBN 9 1894 7101 6, 379 pp. Distributor: Nordicom.


This paper describes the design techniques used in a single chip implementation of an IEEE1451 standard transducer interface chip. The chip integrates an 8-channel 12-bit A-to-D Converter, two 12-bit D-to-A Converters, and an 8052 8-bit microcontroller with 256 Bytes SRAM and 10.5 KBytes Flash EEPROM on a 0.6 /spl mu/m CMOS chip. Key elements of the design flow were the integration of analog mixed-signal and digital ASIC design techniques with an 8052 assembly language simulation environment, and a code monitor for high-level debug.


Review(s) of: Angst: The origins of anxiety and depression, by Jeffrey P. Kahn, Oxford University Press, 2012, 320 pages, $41.95.