PURPOSE
To develop image-analysis algorithms to synthesize CT with accurate electron densities for MR-only radiotherapy of head & neck (H&N) and pelvis anatomies.

METHODS
CT and 3T-MRI (Philips, mDixon sequence) scans were randomly selected from a pool of H&N (n=11) and pelvis (n=12) anatomies to form an atlas. All MRIs were pre-processed to eliminate scanner and patient-induced intensity inhomogeneities and standardize their intensity histograms. CT and MRI for each patient were then co-registered to construct CT-MRI atlases. For more accurate CT-MR fusion, bone intensities in CT were suppressed to improve the similarity between CT and MRI. For a new patient, all CT-MRI atlases are deformed onto the new patients' MRI initially. A newly-developed generalized registration error (GRE) metric was then calculated as a measure of local registration accuracy. The synthetic CT value at each point is a 1/GRE-weighted average of CTs from all CT-MR atlases. For evaluation, the mean absolute error (MAE) between the original and synthetic CT (generated in a leave-one-out scheme) was computed. The planning dose from the original and synthetic CT was also compared.

RESULTS
For H&N patients, MAE was 67±9, 114±22, and 116±9 HU over the entire-CT, air and bone regions, respectively. For pelvis anatomy, MAE was 47±5 and 146±14 for the entire and bone regions. In comparison with MIRADA medical, an FDA-approved registration tool, we found that our proposed registration strategy reduces MAE by ∼30% and ∼50% over the entire and bone regions, respectively. GRE-weighted strategy further lowers MAE by ∼15% to ∼40%. Our primary dose calculation also showed highly consistent results between the original and synthetic CT.

CONCLUSION
We've developed a novel image-analysis technique to synthesize CT for H&N and pelvis anatomies. Our proposed image fusion strategy and GRE metric help generate more accurate synthetic CT using locally more similar atlases (Support: Philips Healthcare). The research is supported by Philips HealthCare.


The present invention discloses an electrical connector terminal and the use of the electrical connector terminals of an electrical connector assembly, the electrical connector assembly comprising: an electrical connector and connected to the chip module and a printed circuit board at both ends of the upper and lower electrical connector electrical connector includes an insulative body and a plurality of electrical connectors accommodated in the terminal, the IC package and printed circuit board are respectively provided with the insulating body and the contact portion of the conductive portion is electrically connected with the electrically conductive terminals, wherein the contact the central portion and the conductive portion is collinear to the vertical direction, thereby providing a standard test fixture of the electrical connector to facilitate the design and manufacture of the test fixture.


Abstract This paper presents a kernel regression approach towards the navigation control of a robotic agent in static as well as dynamic environments where robot's field of operation may comprise number of obstacles. Two different scenarios namely, off-line and online navigation controls, have been examined while dealing with static environment. In off-line case, a fully observable environment, with regards to position information of the obstacles, has been assumed. Whereas in case of online navigation (both static as well as dynamic obstacles), the controller modifies the robot's path at run-time to avoid potential collision(s) as per robot-obstacle vicinity.


Despite mounting concern about cyber attacks, the United States has been hesitant to embrace retaliatory cyber strikes in its overall defense strategy. Part of the hesitation seems to reflect concerns about limits imposed by the law of armed conflict. But analysts who invoke today's law of armed conflict forget that war on the seas has always followed different rules. The historic practice of naval war is a much better guide to reasonable tactics and necessary limits for conflict in cyberspace. Cyber conflict should be open — as naval war has been — to hostile measures short of war, to attacks on enemy commerce, to contributions from private auxiliaries. To keep such measures within safe bounds, we should consider special legal constraints, analogous to those traditionally enforced by prize courts.


Traditional database query languages are based on set theory and crisp logic. Many applications, however, need additionally retrieval-like queries returning the probability of a result object being relevant to a given query object. Traditionally, retrieval systems estimate relevance by exploiting hidden semantics whereas query processing in database systems relies mainly on term matching. Thus, completely different mechanisms were developed for database and information retrieval. As result, there is a lack of support for queries which involve both retrieval and database search terms. In this paper we develop basic concepts for a unifying framework based on quantum mechanics and quantum logic. Rijsbergen already discussed in his book the strong relation between quantum mechanics and information retrieval. The goal of this paper is to discuss the relation of database queries to quantum mechanics. Here, we develop the mapping of select operations as well as conjunction, disjunction, and negation as part of the relational calculus to quantum mechanics and quantum logic.


In recent years technology education has taken a backward seat in primary schools as governments push for evidence that money spent on education is making a difference. Rightly or wrongly, the measure of such difference was equated to skills and abilities in the areas of literacy and numeracy. Unsurprisingly to many the results of such initiatives have been underwhelming to say the least. Those in the fields of technology, science, social sciences have always advocated for an interdisciplinary approach to integration in which these subject or learning areas become the catalyst for the development of literacy and numeracy skills in authentic, student-centred contexts, along with a range of other skills necessary to flourish in a current and future world.


For a realistic value of U = 40 W /m2, the values of d = 0.12 m and velocity (not v) = 0.11 m/s are correct as given.


Managing water supply of the villages and small towns in the province of León has traditionally gone to the neighbors or the Neighborhood Councils (in Spanish Juntas Vecinales). Competence in the management of the water supply is municipal, although most of municipal politicians in the province have not wanted to take on the political costs of doing so. The new legislative changes are intended to service coordination to the provincial council. In this work, we analyze the different modes of water supply management in the province, and the pros and cons derivatives of each other. We propose that the best management method is one in which the neighborhood committees and/or neighbors maintain a basic service management carrying on since immemorial time. Of course, it is associated with a substantial improvement in management and a strict compliance with health regulations imposed by the legislation. An example of how we can improve this management is the case of the villages of Gradefes. In them since 2007 a process of improvement in the management keeping management in the hands of local committees with tutelage and analytical efforts is exercised by the municipal government.


Introduction The Zagros fold-thrust belt in SW Iran is a part of the Alpine-Himalayan system whichconsists of a variety of structures with different sizes or geometries. Morphology of the Zagros Mountains is too complicated, because of impaction of different basement faults during the orogeny. The Izeh fault (N-S trending) is one of these deep-seated faults which its movements had been modified sedimentation patterns and deformation styles of geological units in the Central Zagros. Moreover, it's expected that hydrocarbon migration and accumulation in SW Iran had been affected by this fault system. This paper presents new findings concerning deformation style and mechanism of the Izeh fault. Inasmuch as the RS (Remote Sensing) imagery is one of the valuable means available to geologists for locating geological! geomorphological features expressing regional fault or fracture systems, therefore, the satellite images were used for structural analysis of the Izeh fault. The study area lies between latitude 31030' to 310 52' N, and longitude 49030' to 490 53' E. The geological setting of the area is just between the Izeh Zone and the Dezful Embayment. It has rugged topography and elevation ranged between 548 m to 1499m (from sea level).


This study investigates the determinants of career choice intentions of adolescents with family business background from both adolescents' and parents' views. Comparing three groups of adolescents ("intentional successors," "intentional founders," and "intentional employees") from 106 German family firms through multinomial regression analyses, the authors found personality traits (i.e., Openness and Agreeableness), gender, adolescent identification with the family business, perceived parental job rewards, and parental succession preference and preparation to significantly differentiate adolescents' career choice intentions. Findings add to previous succession research by empirically demonstrating the impact of individual and socialization influences on offspring's succession intentions as early as in adolescence.


Open Government Data (OGD) is where the public sector relinquishes its role as information gatekeeper and become information provider. This realigns power dynamics between the public and private sectors. Open and transparent governments are more accountable to their citizens and less corrupt. Openness generates trust in government, paves way for meaningful citizen participation and more informed and better policies. This paper addresses the question: How does OGD arouse development opportunity generation? To explore and illustrate how development opportunities can be generated using OGD, we proposed a conceptual model that generates noticeable techniques resulting in economic development opportunities. This portrays the contributory pathways between OGD, social factors and technological factors that can generate development opportunities. We looked at overall economic and societal impacts from OGD and examine OGD initiatives as the unit of analysis.


BACKGROUND
The use of functional neurosurgical implants has increased over the past 10 years. PlasmaBlade is an innovative electrosurgical appliance harnessing pulsed radiofrequency (RF) energy. Our aim was to assess the risk of damage to neuromodulation hardware during PlasmaBlade dissection.

MATERIALS AND METHODS
A simulated setting with chicken breast threaded with different hardware and PlasmaBlade used in three configurations. . Post dissection, the wires were inspected naked eye and under an operating microscope. The induced current was assessed contemporaneously using an oscilloscope.

RESULTS
Five surgeons tested the PlasmaBlade at different generator settings. Sixty dissections were undertaken. No structural damage or induced current was identified at CUT 3/4, COAG 5. At CUT 6, COAG 5 and during dissection in a perpendicular orientation with prolonged hardware contact, opacification of insulation material occurred in 15/20 dissections. There was no dissolution of insulation even at this setting. On deviation from Medtronic advice, hardware damaged occurred if one was reckless with the PlasmaBlade.

CONCLUSION
When using the recommended settings and operational technique, PlasmaBlade dissection did not cause any damage to implant wiring/tubing in this simulated setting. This report seeks to add to clinical data suggesting PlasmaBlade is safe for dissection around deep brain stimulator (DBS), vagal nerve stimulator (VNS), and spinal cord stimulator (SCS) hardware.


For two discrete-level quantum systems in interaction, we follow the displacement in the complex plane of the eigen-energies of the compound system when the spectrum of one of the two systems becomes continuous. These new points are usually called resonances. This allows us to define and to calculate a critical value of the coupling constant which separates two well-known coupling regimes. We also give an example of these resonances for the hydrogen atom coupled to the continuum of the states of the transverse electromagnetic field in the vacuum. We justify that some resonances be neglected.


The voice is most prominent & primary mode of communication among the human beings. With this speech human can communicate with machine, thus this technique is used in education, military and medical sectors. Though this is not the new area, from last few decades researchers are working on the improvement of accuracy in voice recognition system. The design of that system concerns major issues such as speech classes, speech styles, vocabulary, transducers, illness and channels; due to all this constraints the noise factor in automatic speech recognition is high. Many researchers have tried to overcome above issues. The recent work in speech recognition is briefly summarized in this paper. Some basic fundamentals of clean and noisy databases of voice samples are also discussed.


We describe a new optical diagnostic for determining the composition of gases by measuring the motion of atoms and molecules trapped within very deep optical lattices. This non-resonant method is analogous to conventional Raman scattering, except that the observed spectral features relate to the oscillatory center-of-mass motion of each species within the lattice, determined uniquely by their respective polarizability-to-mass ratio. Depending on the density of the probed sample, detection occurs either via optical scattering at the high end or via non-resonant ionization at the lower end. We show that such a technique is complementary to conventional mass spectrometry techniques and envision its implementation in existing instruments.


Safety commitment and safety performance have been widely discussed in previous studies. These elements had been found related to safety management practices at the workplace. This study was conducted to assess the paddy farmers safety commitments for improving safety practices and always performing the job safety and are healthy. This study involved 745 registered farmers with the Department of Agriculture in Peninsular Malaysia. The study applied the guided questionnaire and the result has shown all hypotheses had significant relationship towards safety initiatives. It was proven that safety commitment has stronger relationship with safety initiatives over safety management practices. Whereas as mediator, the safety commitment also has significant impact between safety management practices and safety initiatives. Therefore, the safety commitment among farmers should be identified before designing a suitable safety program to encourage them to improve their attitude and proactive measures towards safety.


The disrupted surface of porous membranes, commonly used in tissue-chip and cellular co-culture systems, is known to weaken cell-substrate interactions. Here, we investigated whether disrupted surfaces of membranes with micron and sub-micron scale pores affect YAP localization and differentiation of adipose-derived stem cells (ADSCs). We found that these substrates reduce YAP nuclear localization through decreased cell spreading, consistent with reduced cell-substrate interactions, and in turn enhance adipogenesis, while decreasing osteogenesis.


Hip fracture surgery should be performed as soon as possible after the fracture has occurred. However, surgery sometimes is delayed to address unstable medical problems or for logistical reasons. A likely consequence of delayed surgery is excess risk for venous thromboembolism (VTE). In this study from Korea, researchers determined the prevalence of VTE …


The purpose of this study was to determine the extent to which the Statement of Islamic Accounting Standards, Sharia Audit, Sharia Supervision, Islamic Corporate Governance, and Islamic Work Ethos affect the Quality of Sharia Financial Statement Presentation in the Baitul Wat Mal of Wonogiri Regency Regional Office. This study uses a quantitative approach. Samples were taken by convenience sampling method. The research objects encompass five BMT's located approximately 10 km away from the Wonogiri Regent's Office which consists of three sub-districts, namely Selogiri, Wonogiri, and Ngadirojo. 35 questioners are processed and analyzed using SPSS Version 23. The variables of interest include 12 PSAK, 16 sharia audit, 8 sharia supervision, 3 ICG, 8 Islamic work ethos and 27 quality indicators of sharia financial report. Based on the results of this study, there are many effects of statement of Islamic accounting standards and Islamic work ethos on the quality presentation of Islamic financial statements. On the other hand, Islamic auditing, sharia supervision, Islamic corporate governance can not affect the quality presentation of sharia financial statements. Simultaneous test, the statement of sharia accounting standards, sharia audits, sharia supervision, Islamic corporate governance and the Islamic work ethos at the same time influence on the quality presentation of the sharia financial report.


The capillary gas chromatographic (CGC) analysis of the der-matological drug trans-acitretin (NeotigasonR) and its cis metabolite is described. Separation of the methyl ester derivatives can be achieved on a 90% biscyanopropylsiloxane phase. The importance of using cold on-column injection and short, thin film capillary columns is discussed. For patients treated with the prodrug of acitretin, etretinate (TigasonR), i.e. the ethyl ester of Neotigason, three compounds have to be separated. Selectivity tuning is required for successful CGC separation. An alternative can be found in the selectivity of ion monitoring mass spectroscopy. Analysis of plasma samples involves liquid-liquid extraction, a derivatization step, and HPLC purification.


PurposeThis study aims to analyze the technical, environmental, economic and thermal comfort impacts of implementing passive measures and heating systems in Ciudad Verde, a large-scale social housing project located at the periphery of Bogota, Colombia.Design/methodology/approachA system dynamics (SD) model is proposed to evaluate scenarios through counterfactual experiments, including technical, environmental and economic components. Model inputs are obtained from building energy simulation models and data collected from official reports, public policy documents and construction records.FindingsResults suggest that the use of heating systems is the best choice to achieve thermal comfort conditions throughout the day. However, both the capital expenditures and CO2 emissions associated with such system make their adoption very difficult. In line with that, the use of heating systems in combination with passive measures stands out as a viable solution since their costs are affordable and their use contributes to reducing CO2 emissions.Originality/valueThe proposed model recreates the dynamics underlying social housing construction processes, the adoption of heating systems and passive measures in low-income dwellings and their corresponding impact on CO2 emissions and indoor thermal comfort conditions. The model can be employed as a support tool in the formulation of social housing policies associated with thermal comfort specifications. In this way, the model represents a first step toward incorporating thermal-related variables into the decision-making processes related to social housing planning and development.


In this big data era, personal information and privacy protection sound no longer unfamiliar to us. From using all sorts of computational software and online platforms, registering and using vast amount of social medias in everyday life, to conducting high-technical science researches and national statistical census, people's social announcements, purchase records, health data, daily commutes, career movements, financial status and even personal relationships are enough to constitute a complex and massive data network. Analytic hierarchy process dynamic model; Pricing mechanism and transaction mechanism are used in this paper. Based on the comprehensive consideration of social science theories such as microeconomics and macroeconomics, the pricing structure and bargaining range of privacy information are formulated firstly. Then a discrete choice model with time and dynamic factors is formulated. Secondly, the price trends of different age and occupation analysis models are considered. Thirdly, the social model is improved because the social network is highly correlated. Then use panel data to verify the model, and finally put forward relevant policy recommendations.


Ecological restoration is a cultural choice. I understand our world to be in a crisis of perception: we see ourselves as separate or somehow independent from the natural world. As an artist and a restorationist, I have always sought to foster a sense of reconnection between human culture and the natural world. I try to help people see how, even in the face of dramatic ecological damage, our individual actions will make a difference. Part of the answer is to return to the source with the tools of the future. Through my art, and specifically the imaging of biodiversity, I work to let the life forms of nature express their own beauty, their character, diversity, adaptation, and resilience. For me, this is also work to restore the role of art as visionary vehicle in human civilization.


A vehicle with a vehicle body has an inner part with a plurality of decorative parts. Multiple windows are supported on the structure and are positioned adjacent to the inner part. An electrical charging system includes a rechargeable battery mounted on the vehicle body and configured to receive an electrical charge from an on-board charger and / or an external battery charger and / or a loading station. A display panel is connected to the electric charging system and attached to one of the trim. The display panel is configured to display information indicating a status of the electrical charging system. The display panel is mounted in such a position that the information is visible from a position outside of the vehicle body.


A discussion of fandom's resistance to seeing a woman cast as 'the Doctor' in the popular science fiction television show 'Doctor Who'.


The modern population, while living versatile lives of rather
strong individual traits, are constantly seeking for the
opportunities get intimated with the natures and to be deeply
associated with the on-going cultures of general popularity.
With the above views in mind, this study had devoted to review
the amusement parks in the country.
Four existing parks have been selected for the study, but
elaborated in detail particularily for the riding facilities.
The riding facilities there have been reviewed and analysized
in detail by type, size, zoning, space allotment, research an
the actual condition etc. and the problems encountering with them
have been discussed.


This article looks at text-based syllabus design as a way of providing teachers with a systematic framework for developing content, sequence and methodology in ESL teaching.


Draft of an article about Khallid Muhammad, a black activist who made inflammatory statements about the government, gays, and white people at a speaking engagement.


Government is currently undertaking a rare review of the way teachers are trained as part of its decade of educational reforms. Grave disquiet has been expressed by Ministers over the adverse effects of many years of inept experimentation and adherence to dubious ideologies. Particularly singled out for attack has been a supposed preoccupation with the theoretical aspects of professional training. The absence of substantial research in the important area of teacher training makes such opinions a matter ofjudgement and there is a contrary school of thought which argues that the professional induction of teachers this century has been anything but radical, being characterised by adherence to traditional practices and conventions. The present interest by government is exceptional, no government since the war having shown any serious interest in the complex and difficult processes which by common consent among educationists for generations, are desirable to produce a highly educated and competent teaching force. It may be instructive in a period of controversy at the end of the century to draw attention to an experiment at its beginning which raised many of the same issues. The example has been chosen because at its centre was the theory/ practice dichotomy which was then becoming a debating point as knowledge of child development increased, as the processes of education come under scrutiny, as notions of teacher professionalism evolved, but most of all, as the universities engaged in the training of teachers and judged the traditional methods of the training colleges and pupil teacher system to be restrictive and inflexible. How far university involvement was in fact radical and innovative must remain speculative as little research has probed this important extension of professional training. It is clear, however, that J. J. Findlay, from 1903 Professor of Education in the University of Manchester, was one of the few to have a clear perception of what that role entailed. In his Inaugural lecture, The Training of Teachers', he


Various precision determinations of the Fermi constant are compared. Included are muon and (leptonic) tau decays as well as indirect prescriptions employing \ensuremath{\alpha}, ${m}_{Z},$ ${m}_{W},$ ${\mathrm{sin}}^{2}{\ensuremath{\theta}}_{W}{(m}_{Z}{)}_{\overline{\mathrm{MS}}},$ $\ensuremath{\Gamma}(\stackrel{\ensuremath{\rightarrow}}{Z}{l}^{+}{l}^{\ensuremath{-}}),$ and $\ensuremath{\Gamma}(\stackrel{\ensuremath{\rightarrow}}{Z}\ensuremath{\nu}\overline{\ensuremath{\nu}})$ as input. Their good agreement tests the standard model at the \ifmmode\pm\else\textpm\fi{}0.1% level and provides stringent constraints on new physics. That utility is illustrated for heavy neutrino mixing, two-Higgs-doublet models, S, T, and U parameters, and excited ${W}^{*\ifmmode\pm\else\textpm\fi{}}$ bosons (Kaluza-Klein excitations). For the last of those examples, ${m}_{{W}^{*}}\ensuremath{\gtrsim}2.9\mathrm{TeV}$ is found.


Peroral pancreatoscopy (POPS) under duodenoscopic assistance provide direct visual assessment of the pancreatic duct, tissue sampling, and therapeutic interventions. Sometimes, pancreatoscopy can confirm accurate diagnosis, such as differential diagnosis of filling defects between intraductal tumors and stones. However, it is often difficult to differentiate malignant from benign strictures solely on pancreatoscopy. It is currently considered that intraductal papillary mucinous neoplasm (IPMN) is the most suitable indication of POPS. POPS has several problems: image resolution, fragility and maneuverability. Concerning image resolution, the quality has been improved with the development of a video pancreatoscope. Moreover, the recently developed endoscopic optical technology of narrow band imaging (NBI) is now available to video pancreatoscopy. This will allow direct visual assessment. Although currently POPS has several problems, further improvement will assist POPS to become a useful modality in combination with NBI.


In 2007,Wang obtained a result about DNA labeling graphs which do not contain loops.On this basis,we generalized a sufficient and necessary condition for general directed graphs.We conclude that the sufficient and necessary condition for any directed graphs,which do not contain isolated vertices have and only have a equivalence class under the friend relationship and we draw some improved results accordingly.A counterexample of a theorem is given,too.Furthermore,we modified and completed this theorem.It is easy to deduce that the necessary condition for the theorem in Wang's research is also a sufficient condition.


Abstract This essay discusses the media reaction to Ang Lee's recent movie, Brokeback Mountain. Earlier cowboy films with same-sex themes and subtexts and reaction to the Best Picture Oscar selection are also discussed.


The optimal solution provided by metaheuristics can be viewed as a random variable, whose behavior depends on the value of the algorithm's strategic parameters and on the type of penalty function used to enforce the problem's soft constraints. This paper reports the use of parametric and non-parametric statistics to compare three different penalty functions implemented to solve the Security Constrained Optimal Power Flow (SCOPF) problem using the new enhanced metaheuristic Differential Evolutionary Particle Swarm Optimization (DEEPSO). To obtain the best performance for the three types of penalty functions, the strategic parameters of DEEPSO are optimized by using an iterative algorithm based on the two-way analysis of variance (ANOVA). The results show that the modeling of soft constraints significantly influences the best achievable performance of the optimization algorithm.


Abstract The business world is changing due to the occupational climate and a large proportion of business executives that are bound to retire in the nearest future leading to an anticipated great loss of knowledge and performance. The paper seeks to evaluate job performance by considering the effect of mentoring on employee performance in the Nigerian service sector. Research focuses on finding out the level at which exposure, counseling, and role modelling affect employee performance in the Nigerian service sector.


In this article we begin by discussing 'ideology' as a theoretical construct, and the interconnections between policy and ideology in the education system in England. We analyse the main principles of education policies that can be broadly defined from Left to Right, according to the following ideologies: Marxism/Socialism/Radical Leftism, Social Democracy, Liberal-Progressivism, Neoliberal Conservatism and Neoconservatism. We then move on to analysing responses to inequalities, as informed by different ideological positions, and identify three main types of responses: (1) conforming; (2) reforming; and (3) transforming. The article concludes by addressing some historical developments in terms of equality in early years and identifies key implications for leadership and management.


This study has the general objective to analyze the proper treatment in different cases of aortic stenosis, focusing on the surgical treatment, more specifically in Percutaneous Transcatheter Aortic Valve (VATP) and aortic valve replacement without suture. This work was a review of the literature conducted in August 2018. After the selection of jobs that met the inclusion criteria, the selected material was analyzed, and the results presented in tables, carrying out a qualitative study to characterize the publications found. The study showed that surgery is indicated for symptomatic patients, requiring that care be taken for those patients who are in the risk allo group, asymptomatic patients the most appropriate option is the vigilant monitoring, as it does not offset the risk brought by surgery. It should be noted that the TAVI was indicated as the most used technique for performing surgery in patients with aortic stenosis. *Correspondence to: Camila Alcalde Mazza, Avenue José Munia, 6300São José do Rio Preto/SPBrazil; Tel: 5517997884321; E-mail: firstname.lastname@example.com


Uroleucon sonchi, an aphid species of Palaearctic origin, is a recent adventive to Australia. It is now widespread in anthropic areas of all states and the Australian Capital Territory, principally on sowthistles (Sonchus spp.) but also on lettuce. It is occasionally parasitised by Aphidius sonchi Marshall (Hymenoptera: Braconidae). Its possible economic importance in Australia is discussed. The species is also recorded for the first time from Norfolk and Philip Islands.


The National Science Olympiad (OSN) is an annual agenda organized by the Directorate General of Primary and Secondary Education. . In order to carry out one of the tri dharmas of higher education, community service is one of the tasks that must be carried out by the lecturer staff. Implementation of activities carried out in the form of providing materials, demonstrations and discussions. Natural phenomena and daily events are closely related to the world of geography, but in general, geography lessons for students are still considered quite difficult and boring subjects. This is indicated by the geography test scores obtained by most students are still not satisfactory.


A simple scheme is presented for generating n atom W states with the two-photon resonant interaction between atoms and cavity field.In the proposed protocol,it is injected a two-level atom initially prepared in the excited state through the cavity prepared in the vacuum state.The other two-level atoms prepared in the ground state are injected into cavity.Because the interaction between the atoms and cavity field is resonant,the coupling strength can be relatively strong which will shorten the corresponding interaction time and thus reduce the effect of decoherence in experiment.


In this paper,simple supporting beams with openings are taken as the subject for analysis when the openings are located in bending shear sections and pure bending sections,thus to find out the influence of depth,length and location of the openings along the beams on the mechanical behaviors and displacement. The calculating method of the beams is discussed.


A catalyst for selectively removing NOx, hydrocarbon and CO from the tail gas of diesel engine, gasoline engine and gas engine is prepared from Ag component and porous inorganic oxide as carrier. Itsapplication method features that the catalyst is arranged in the tail gas pipe, the organic substance as reducer is put at upstream of said catalyst, and the mixture of said reducer and tail gas is contacted with catalyst at 150-600 deg.c to reduce Nox into NO2, and oxidize the residual reducer into CO2 and H2O.


One of the challenges to realizing the hydrogen economy is hydrogen compression and storage issues. Recent developments in proton exchange membrane (PEM) technology have offered possibilities for efficient electrochemical compression of hydrogen. This alternative method offers operational and efficiency benefits over the conventional mechanical compressor. Efficient hydrogen compression can improve the overall efficiency of a renewable hydrogen production system. This paper summarizes the modeling of a PEM electrochemical compression system. Modeling was done using the Mathematica software to calculate the energy requirement of electrochemical compression at different output pressures. The PEM cell compressor can be used as an intermediate step to mechanical compression to reduce the number of compression stages and energy usage. Results from the theoretical calculations are used to compare energy use for the combination of PEM cell and mechanical compression with mechanical compression alone, over a wide pressure range.


Aiming at the limit of classical job-shop problem, combining with actual manufacture instance, a rout flexible job-shop model was given, a machine choose rule was advanced, the process of improved ant colony algorithm was given. After all ants crawled, this algorithm could adjust pheromone aiming at whether it got into part convergence, this could help algorithm to get best solution faster. In the end the simulation results show that this algorithm has good performance.


ABSTRACT The objective of this study was to evaluate the level of sustainability of conventional and organic dairy cattle production units (CPU) in the Zoque Region of the Mexican state of Chiapas through evaluating attributes and indicators of sustainability and through a sustainability index (SI) value. Four organic or conventional CPU with high or low SI values were identified. The organic CPU with high SI had the highest SI value. The attribute of sustainability self-management contributed more to the SI value. All CPU need to strengthen some of the attributes of sustainability evaluated.


Contributors Introduction: Harvard Sitkoff 1. The Twentieth-Century Presidency: 2. Piety and Property: Conservatism and Right-Wing Movements in the Twentieth Century: 3. Twentieth-Century Liberalisms: Transformations of an Ideology: 4. The Republic as Empire: American Foreign Policy in the "American Century": 5. Work Places: The Economy and the Changing Landscape of Labor, 1900-2000: 6. The History and Politics of Poverty in Twentieth-Century America: 7. Citizens and Consumers in the Century of Mass Consumption: 8. American Women in the Twentieth Century: 9. "You duh Man!": African Americans in the Twentieth Century: 10. From the Benighted South to the Sunbelt: The South in the Twentieth Century: 11. Democracy, Citizenship, and Race: The West in the Twentieth Century: 12. The Chameleon with Nine Lives: American Religion in the Twentieth Century: 13. Immigration and Ethnicity in the American Century: 14. The Iron Cage and Its Alternatives in Twentieth-Century American Thought: Index


The amino radical has been produced by reaction of the OH radical with ammonia in irradiated aqueous solutions. At pH 11.4 the unprotonated radical, NH/sub 2/, is produced with a rate constant k = (9 +- 1) x 10/sup 7/ M/sup -1/ s/sup -1/, while in acidic solution the corresponding reaction of OH with NH/sub 4//sup +/ is too slow to be observed. The SO/sub 4//sup -/ and PO/sub 4//sup 2 -/ radicals are found to react more slowly with NH/sub 3/ than does OH. It is concluded that these radicals react with ammonia by hydrogen abstraction and not by electron transfer oxidation. The method is not useful for the production of the protonated NH/sub 3//sup +/ radical. The subsequent reactions of NH/sub 2/ are followed by monitoring the kinetics of formation of the more strongly absorbing radical products. Rate constants for the reactions of NH/sub 2/ with various substituted phenoxide ions have been measured; with phenoxide itself at pH > 11, k = 3.0 x 10/sup 6/ M/sup -1/ s/sup -1/. These rate constants are strongly affected by the ring substituent. When the rates are plotted against the Hammett sigma values, a slope corresponding to rho approximately = -3.3more » is derived. The mechanism is considered to be oxidation of the phenoxide ions by electron transfer. Although the NH/sub 2/ radical was found to be relatively unreactive toward addition to benzene, its adduct radical to the fumarate anion has been observed by ESR. The NH/sub 2/ radical may also be produced by reaction of e/sup -//sub aq/ with NH/sub 2/OH. An attempt was made to generate the NH/sub 3//sup +/ radical in the corresponding reaction with the acid form of hydroxylamine, /sup +/NH/sub 3/OH, which is especially fast. On the basis of several pieces of evidence, we postulate that NH/sub 3//sup +/ cannot be the main product of this reaction but that /sup +/NH/sub 3/OH splits preferentially into the OH radical and NH/sub 3/. 1 table, 1 figure.« less


A nonlocal quantum-field model is constructed for the system of hydrodynamic equations for incompressible viscous fluid (the stochastic Navier--Stokes (NS) equation and the continuity equation). This model is studied by the following two mutually parallel methods: the Wilson--Polchinski functional renormalization group method (FRG), which is based on the exact functional equation for the generating functional of amputated connected Green's functions (ACGF), and the Heemskerk--Polchinski holographic renormalization group method (HRG), which is based on the functional Hamilton--Jacobi (HJ) equation for the holographic boundary action. Both functional equations are equivalent to infinite hierarchies of integro-differential equations (coupled in the FRG case) for the corresponding families of Green's functions (GF). The RG-flow equations can be derived explicitly for two-particle functions. Because the HRG-flow equation is closed (contains only a two-particle GF), the explicit analytic solutions are obtained for the two-particle GF (in terms of the modified Bessel functions $I$ and $K$) in the framework of the minimal holographic model and its simple generalization, and these solutions have a remarkable property of minimal dependence on the details of the random force correlator (the function of the energy pumping into the system). The restrictions due to the time-gauged Galilean symmetry present in this theory, the problem of choosing the pumping function, and some generalizations of the standard RG-flow procedures are discussed in detail. Finally, the question of whether the HRG-solutions can be used to solve the FRG-flow equation for the two-particle GF (in particular, the relationship between the regulators in the two methods) is studied.


Structure Condotel Grand Darmo Suite Surabaya planned 13 floors and is located in the region quake 2. The final task is to plan the structure of the building of reinforced concrete using System Frame bearers Special Moment (SRPMK).  Building System model frame bearers Special Moment (SRPMK) using the concept of Strong Column and Weak Beam (strong column and weak beam) in accordance with SNI 03-2847-2002 and SNI-1726-2002. Planning the structure of the building using the concept of design capacity. Structure is reviewed by using the analysis of load effects equivalent static and structural analysis calculated with the help of the program SAP2000 v11.  Results of the structural design Condotel Grand Darmo Suite Surabaya consisting of concrete frame with reinforcement diameter (D22, D19, D16, D13, and P10), shear wall thickness of 25 cm, the roof using a reinforced concrete slab and foundation using concrete piles precast diameter of 40 cm and 50 cm. Calculations that have been done show that all elements of the building structure is safe in the analysis.


The economic dispatch (ED) of distributed energy resources (DERs) is an important and challenging problem in smart grid operation. Different frameworks are proposed for solving this issue, among which the virtual power plant (VPP) is considered as a promising means for ED in smart grids with DERs. This study presents a novel optimisation algorithm entitled sequence-based differential evolution (SDE) for solving generation dispatch among several DERs with VPPs. In the proposed method, a novel and efficient initialisation technique, namely sequence-based deterministic initialisation, is used to generate high-quality initial population. Besides, a self-adaptation mechanism is utilised to eliminate the difficulty of tuning the problem-specific control parameters of the algorithm. Subsequently, the SDE is applied for solving the ED model to obtain the optimal power generation share of the VPP. Case studies compare the solutions obtained by the proposed method with several state-of-the-art algorithms in the existing literature. It is validated the proposed method is advantageous for ED with VPPs in better solution accuracy, less computational burden, and faster convergence.


Dynamic rational expectation storage models with uncertanty conditions applied to Brazilian rice market The aim of this study was to analyze rice storage in Brazil, proposing a model for decision taking regarding stock formation. Once these models are known it is possible to previously analyze the government interventions. Thus, the study was based on the hypothesis that it is possible to represent the rice market in Brazil through a dynamic model of rational expectations able to analyze the product importation effect and some policies of price support to the producer adopted by the Brazilian government. The methodological proposal for estimating the model follows the dynamic programming approach. It was developed algorithms which represent the rice market in Brazil in a situation of closed market without the government intervention, open market without government intervention, closed market with the government intervention through PEP (Prêmio de Escoamento do Produto – Prize for Product Outletting), closed market with the government intervention through AGF (Aquisição do Governo Federal – Federal Government Acquisition), open market with the government intervention through PEP, open market with government intervention through AGF. The methods used for the solution require that it be known the demand and supply functions for the area, the unit storage cost, the annual interest rate, the distribution of probabilities of random variables (productivity and demand shocks), importation and minimum (whenever is the case) prices. The expected market prices in the situation of open market with intervention through PEP were slightly lower than to the market price without intervention, however the price received by the grower was a little higher. It means that part of the PEP resources is allotted by the grower and part by the industry. The results of the open model with AGF show that the prices for the buyer are higher than those found in the model without government intervention. Another result was that the level of minimum prices practiced over the last years has not been adjusted to the point to promote significant changes in the balance of the domestic market.


With the development of Science and technology, the society has entered the information age, 4g communication technology has already been popularized all over the country, and the application range of wireless network has been gradually expanded, showing a broad development prospect of China's communication industry. However, in the development of 4G communication technology wireless network, the security problem also comes along, threatening the users' life, property, security and even life safety, which also becomes the main factor to hinder the development of the communication industry. Based on 4G Communication Technology, this paper discusses the secure communication of wireless network, in order to prevent the possible security problems in advance, provide guarantee for communication and promote the steady development of the whole industry.


Oxidation mechanisms of methyl linoleate with (TML) were investigated by determining oxidized products using GC-MS during oxidation at for 9 days. Oxidized products of TML were found to be methyl octanoate, methyl-8-(2-furyl)-octanoate, 9,13-trans, cis isomer and 9,13-trans, trans isomer. In previous report, oxidation products of methyl linoleate(ML) were methyl-8-(2-furyl)octanoate, 9,13-trans, cis hydroperoxide isomer, 9,13-trans, trans hydroperoxide isomer, and 9-TMSO-12,13-epoxy-10-octadecenoate. In the case of ML, 9-TMSO-12,13-epoxy-l0-octadecenoate was produced instead of methyl octanoate in TML. quinone, as a major oxidized product of was formed at the 6th day of oxidation. quinone was produced rather quickly in lipid media than aqueous media. In oxidation of methyl linoleate, it was shown that the first oxidized product was methyl-9,13-hydroxy-octadecadienoate. As second products, methyl-8-(2-furyl)-octanoate, 9-TMSO-12,13-epoxy-10-octadenoate, and methyl octanoate were oxidized from methyl-9-hydroxy-10-trans, 12-trans-octadecadienoate.


In order to understand how the in-situ primary stress state has evolved with subsidence and uplift in a granitic rock mass for anticipated of a radioactive waste repository in Hungary, the authors investigated the applicability of seismic tomography as an interpretive tool. Very high P wave velocity (Vp) values were obtained during the tomographic scanning of the study area of the repository, and these were compared with existing findings of in-situ and laboratory seismic measurements.Apart from seismic tomographic survey, dynamic FEM numerical modelling, empirical calculations of residual stresses, laboratory measurements of compression wave (ultrasonic) velocities on intact rock cores, in-situ primary stress measurements as well as site geological model were integrated to evaluate the use of seismic tomography for identifying possible in-situ stress increases around the excavation.A detailed calibration modelling was carried out based on the site seismic tomography measurements and during the large-scale modelling. It was observed that the increasing Vp is directly related to simulated increasing directional loadings on the rock mass. Using a measured wave raypath it was possible to check the different in-situ stress parametrizations which resulted in the best approximation to the measured Vp values.It was concluded that the rock mass under investigation to extend the repository must have higher in-situ stress values than the area of the constructed deposition chambers nearby. The results of this research indicated that seismic tomography is a useful tool for determining relative stress around and within the vicinity of underground excavation.


This Paper proposes target search method for a heavyweight torpedo to detect evading ship effectively by using fuzzy inference. Warship defends itself by conducting evading maneuver and by using decoy, when a torpedo attacks it. These days the research on a torpedo is usually focused on how to distinguish a target from decoys. As a result of the research, a wire-guided torpedo and a wake homing torpedo are developed. In this paper, the efficient target search method using fuzzy inference against the evasive maneuver of anti-torpedo system is proposed, and proves it by simulation.


Objective:To study the effect of insulin on abnormal glucose metabolism in acute cerebral infarction patients with stress hyperglycaemia and evaluate its short-term efficacy.Methods:Eighty-four acute cerebral infarction patients with stress hyperglycaemia were randomized into the treatment group(42 cases,insulin,H.i)and the control group(42 cases,glipizide P.o).The meeting-target time of blood glucose and Barthel index after 3 months of treatment were examined,and main malign events and side-effects during the therapy were observed.Results:The meeting-target time of blood glucose in the treatment group(2.8±1.3)days was significantly shorter than that in the control group.Barthel index three months after therapy was significantly higher compared with that in the control group(P0.01).Main malign events during therapy in the treatment group were less than those in the control group,but with no significance(P0.05).Conclusion:Insulin is superior to glipizide in improving the glucose metabolism and the living ability of acute cerebral infarction patients with stress hyperglycaemia.


the beach and cliffs at anglesea.--split point and lighthouse airey's inlet.--four miles of beautiful beach at eastern view.--looking from big hill to lorne.--herschell's fernery near big hill great ocean road.--a section of the great ocean road.--hairpin bend great ocean road.--louise falls near the great ocean road.--difficult work in the construction of the great ocean road.--the toll house great ocean road.--the great ocean road winds its way to lorne.--devil's elbow great ocean road.--a composite view from cinema point.--panorama of eastern view.--lorne through the gums.15 foldout views. the rose stereograph co. armadale vic. art printers printed on cover: the road of a thousand charms/the devils elbow


precipitation theory measurement and distribution is available in our book collection an online access to it is set as public so you can get it instantly. Our books collection hosts in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the precipitation theory measurement and distribution is universally compatible with any devices to read.


In the polymeric title compound, [Zn(C6H14O2PS2)2(C12H10N4)]n, the Zn atom lies on a centre of inversion and the bridging diimine ligand is disposed about another centre of inversion. The Zn atom is in an octahedral geometry defined by a trans-N2S4 donor set. The polymer topology is that of a step-ladder.


This paper demonstrates the advantages of using a hybrid reinforcement–modular neural network architecture for non-linear control. Specifically, the method of ACTION-CRITIC reinforcement learning, modular neural networks, competitive learning and stochastic updating are combined. This provides an architecture able to both support temporal difference learning and probabil istic partitioning of the input space. The latter is formed with the aid of competitive learning algorithms, so as to ensure suitable partitioning of the experts in the modular network. Application of this methodology to the pole-balancing benchmark non-linear control problem demonstrates superior partitioning of the input space, bettering that of equivalent reinforcement networks; whilst avoiding the learning-to-learn nothing effect, as is often the case when performing gradient decent over problems requiring adaptation over long temporal dependencies.


Cultural studies and languages is Antropolinguistics study. Toba Batak language will change if the ecological support having changed anyway. Language Batak Toba area of research is in three sub-districts, Samosir, Laguboti, Porsea in Toba Samosir. The problem is, how the extinction of medicinal plants caused lexical sosial¬-cultural changes, the benefits of medicinal plants, community efforts to conserve medicinal plants in Toba Batak society? The goal is to describe the medicinal plants due to socio-cultural changes, the benefits of medicinal plants, medicinal plant conservation in Toba Batak society. This research was conducted using qualitative and quantitative. In analyzing the data in the study of medicinal plants vocabulary Batak Toba Match method is used. Use of drugs like this are usually relegated to the younger generation in a way put the drugs directly. The treatment process is usually done for generations, from parent to child by practicing or teaching the treatment process.


A new observer, namely a cascade observer, for a general class of nonlinear SISO systems was presented by the authors [1]. Inspired by but different from a highgain observer, the cascade observer features a cascade structure and adaptive observer gains. In doing so the cascade observer attempts to overcome some of the typical problems that may pose to a high-gain observer. Based on the cascade observer, the estimation problem of the angular link velocity is presented in this paper. As in the case of a highgain observer, the cascade observer structure is simple and universal in the sense that it is independent of the system dynamics and parameters. It is shown that the proposed cascade observer is applicable to robotic state estimation using only joint position measurements effectively.


The use of complementary and alternative medicine (CAM) is commonplace in people managing chronic disease. This RESEARCH ROUNDup highlights evidence for the medication -based CAM used to address chronic conditions considered national priority areas in Australia. Nevertheless, more high quality evidence on prevalence of use, concurrent use of other medications and profiles of CAM users particularly for specific conditions is required for consumers, clinicians (both CAM and non CAM), regulators, educators, researchers, policy-makers and funders.


This paper presents an overview of the low power RF system proposed to be used on the DIAMOND project. It will include detailed technical descriptions of some of the hardware building blocks and show that the use of amplitude insensitive phase detectors, originally developed at Daresbury for use on the Pohang Light Source (PLS), considerably simplifies some aspects of the design.


The invention relates to fluorescence immune chromatography test paper which is formed by mutually and sequentially overlapping a sample pad, a combination pad, an antibody carrying film and water absorbing paper on a lining board with adhesive, wherein the combination pad is coated with a fluorescence material antibody 1 composite, a fluorescence-marked material is fluorescein granules or fluorescence material converted by rare earth, the antibody carrying film is a cellulose nitrate film or a nylon film and is respectively connected with an antibody 2 and the T line and the C line of a secondary antibody, the fluorescence material is fluorescein granules or the fluorescence granules converted by the rare earth, and the fluorescein granules are selected from isosulfocyanic acid fluorescein or tetramethyl isosulfocyanic acid rhodamine or tetraethyl rhodamine, and the surface of the fluorescence-marked material is aminated and combined with the antibody by cross-linking reaction. The fluorescence quantitative measuring system is used for detecting the fluorescence strength of the areas of the T line and the C line, and the quantitative detection is completed by the standard curve of the antigen concentration. The invention is suitable for the immune detection of tumor marked objects of urinal fiber-connected protein, and the like.


The article presents the results of studies of the influence of ambient temperature on the modes of heat and moisture treatment of concrete. The method of assignment of modes of heat and moisture treatment of concrete, taking into account the temperature of the hot climate, is proposed.


F or the past 2 decades, an increasing number of women have entered medical schools and residency training programs and have joined medical school faculties. At present, women make up 39% of students entering medical school and 28% of residents in accredited residency programs (l), and many of them are choosing to have children during the years of their training. A recent study (2) of full-time women faculty in departments of medicine found that approximately 50% of the women had their first child and 33% had their second child during medical training. Therefore, training programs must be prepared to respond to the needs of residents before, during, and after pregnancy. However, many programs have not done so, as evidenced by a recent American Medical Association (AMA) survey which reported that fewer than 45% of programs had specific maternity leave policies (3). Addressing the physiologic and psychologic needs of pregnant residents has important implications for the health of both the mother and infant. Several studies of pregnancy in physicians have indicated that women physicians are at increased risk of adverse outcomes including pre-term labor and pre-term delivery, low birth weight, and abruptio placenta (4-7). Residents seem to be at the most risk, a fact that may be related to demanding work hours and to standing for long periods of time. In addition, psychologic stress appears to be a risk factor for pre-term labor and preterm delivery (8-l l), and the psychologic stress of residency has been documented by numerous studies ("house officer syndrome" [ 12, 131) . However, no definitive studies have evaluated the effect of psychologic stress during residency on pregnancy. After delivery, many women must decide when and how to return to work while they continue to meet the needs of their newborn. Child development experts have explored the effects on children of mothers returning to work at various stages. Although data are scarce, most experts strongly suggest that a parent should be the primary care-giver for at least the child's first 4 months (14, 15). Some child care experts recommend substantially longer maternity (paternity)


Fish is more vulnerable to deterioration than chicken and red meat as it contains relatively larger amounts of free amino acids, a higher water activity and a higher final pH, limiting the shelf life of the product. Hygienic handling practices can control the deterioration of fish quality during storage and distribution. The quality changes and shelf life of iced (0C) and chill (4C) stored sutchi catfish (Pangasianodon hypophthalmus) steaks was assessed by evaluating the changes in biochemical, textural, microbiological and sensory attributes during storage. The study revealed that all the biochemical quality indices studied like pH, TVBN, TBA and PV were within the acceptable range for both the treatments throughout the storage period. However, the chill stored steaks showed higher degree of textural deterioration than the ice stored steaks. Total mesophilic and Enterobactereaceae counts were lower in ice stored steaks compared to chill stored steaks. Based on the sensory and microbiological analysis, the shelf life of chilled and ice stored sutchi catfish steaks is determined as 14 and 17 days, respectively, during storage.


Carfilzomib (CFZ) is a proteasome inhibitor associated with cardiovascular (CV) adverse events (AEs) mainly hypertension (HTN) and cardiac dysfunction. Endothelial dysfunction is a major mediating mechanism in cardiovascular diseases and endothelial function may be adversely affected by proteasome inhibition. However, CFZ effects on endothelial and vascular function and associations with inhibition of proteasome activity have not been explored in humans. We prospectively evaluated CFZ effects on endothelial function and underlying mechanisms as well as baseline vascular function and its response to treatment as potential predictors of CFZ-associated CV toxicity.
 In this prospective study (NCT03543579), 48 relapsed/refractory myeloma patients (median 1 (1-3) lines of therapy, median age: 67.5, 67% men) received Kd [CFZ 20/56 mg/m2 and dexamethasone] in routine practice. A detailed medical history and evaluation of risk factors for cardiotoxicity [age≥65 years, obesity, smoking, HTN, hypercholesterolemia, diabetes mellitus, previous anthracyclin use, chest or mediastinum radiotherapy and current myocardial disease] were recorded. Before CFZ start and at prespecified timepoints cardiac echo, hemodynamic parameters and vascular function that reflect pivotal mechanisms involved in development of HTN and CV events were non-invasively assessed [aortic blood pressure and arterial wave reflections, aortic stiffness and endothelial function using flow-mediated dilatation of the brachial artery (FMD)] along with 24h ambulatory blood pressure monitoring. Proteasome activity (PrA) was measured in peripheral blood mononuclear cells (PBMC) before and 2 hours post CFZ infusion on days 1 (FMDbaseD1 and FMDpostCFZD1) and 2 (FMDbaseD2 and FMDpostCFZD2) of cycle 1 and at prespecified time points concurrently with vascular function assessment. CV AEs were recorded and rated according to CTCAE v4.03.
 The prevalence of risk factors for cardiotoxicity was high (median 3 factors, IQR 2-4). After first CFZ dose, FMD decreased acutely at 2 hours (FMDbaseD1: 5.2%, IQR: 3.2-7.4 vs FMDpostCFZD1: 3.6%, IQR: 1.5-4.7, p=0.008), which partially recovered before and after second CFZ infusion (FMDbaseD2: 4.1% and FMDpostCFZD2: 4%, as compared to FMDbaseD1) (Figure1A). However, FMD decrease was more pronounced among patients who subsequently had lower recovery rate of PBMC PrA 24 hours after first CFZ administration (FMDbaseD1: 5.1%, vs FMDpostCFZD1: 3%, p=0.002) while FMD was not decreased significantly in those who had higher recovery rates of PrA (FMDbaseD1: 5.3%, vs FMDpost CFZD1: 4.5%, p=0.197, Figure 1B), suggesting that the ability to recover PrA is implicated in CFZ induced endothelial dysfunction.
 At the time of analysis, enrolment has completed; 35 patients are still receiving therapy, 13 have discontinued Kd and median follow up is 4.73 months. CV AEs were recorded in 17 (35.4%) patients [HTN(Gr3): 20.8%, Gr3 Left Ventricular dysfunction : 8.3%, Gr3 acute coronary syndrome: 4.2%, Gr3 pulmonary embolism: 2.1%] and generally occurred early (median time to CV event 2.9 months). Kd was discontinued in 2 patients (4.2%) due to cardiotoxicity and in 2 patients (4.2%) CFZ dose was reduced due to cardiotoxicity; no CFZ dose reduction or discontinuation was needed for HTN.
 Among clinical and hemodynamic parameters assessed at baseline, patients with higher aortic SBP (i.e at higher quartile) had a higher risk of HTN even after adjustment for age, gender and baseline HTN (HR=8, 95%CI 2.4-26, p=0.001 and HR=4.9, 95%CI 1.5-15, p=0.007 respectively). Lower PrA recovery rate was associated with increased risk of developing Gr3 HTN (log-rank test p=0.01). Higher post-CFZ reduction of FMD was associated with HTN in patients not receiving statins but not in those receiving statins (a drug class strongly affecting FMD), indicating that statin treatment may exert protective effects against CFZ-related CV toxicity.
 In conclusion, CFZ causes acute endothelial dysfunction; however, higher recovery of proteasome activity is associated with ameliorated depression of endothelial function. Given that poor proteasome recovery rate and acute deterioration of endothelial function are both associated with development of HTN, these findings may improve our understanding of CFZ-related CV toxicity and its prevention. The study is ongoing and more data will be presented at the meeting.

 Kastritis: Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees; Amgen: Honoraria, Membership on an entity's Board of Directors or advisory committees; Prothena: Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees. Terpos:Amgen Inc.: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel grant, steering committee member, Research Funding; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: member of DMC, Research Funding; Genesis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel grant, Research Funding; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: member of steering committee, Research Funding; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel grant, Research Funding; BMS: Consultancy; Novartis: Consultancy. Dimopoulos:Bristol-Myers Squibb: Honoraria; Amgen: Honoraria; Takeda: Honoraria; Celgene: Honoraria; Janssen: Honoraria.


This study investigated physicochemical characters and biotoxicity of waste water and leachate of waste residue from MoO3 produced using physicochemical analysis and biotoxicity test.The result indicates that the waste residue belonged to hazardous waste(Ni、Cd),and also physicochemical characters of the leachate and waste water were lower pH,high heavy metals that exceeded the standard GB 8978-1996,and sometimes had big acute toxicity on Daphnia carinata.The toxicity of leachate and waste water was LC50(24h)0.2542%,LC50(48h)0.0995%,LC50(96h)0.0625% and LC50(24h) 0.0257%,LC50(48h) 0.0240%,LC50(96h) 0.0209%.Volume percentage of safety discharge was 0.00065% and 0.00021%,and the toxicity of waste water was higher than leachate according to LC50(24、48、96h).


In this paper, we proposed the location tracking system based on MS-Based/Assisted(Mobile Station-Based and Assisted) location trigger service model with context-awareness for the intelligent location tracking of moving objects. It provides the proper resulting value that matches the context of users through the analysis about the situation of the user, physical environment, computing resource and the existing information on user input. In order to provide real-time data, we proposed the location tracking system which realizes the intelligent information such as the expecting arrival time and passing the specific area of the moving object by adopting the location trigger. So, it derives to minimize the costs of communication for the mobile object tracking applications. The proposed location tracking system based on context-awareness can be used for realtime monitoring, intelligent alarm/action, setting up of the optimized moving path, dynamic adjustment of strategies and policies. So it has the advantage to develop the application system which is aimed at optimization of the object tracking and movement.


This document is a report of activities performed by Westinghouse Advanced Energy Systems Division-Nevada Operations at the E-MAD Facility, Area 25, Nevada Test Site, in meeting subtask objectives during the first quarter of Fiscal Year 1981. These activities include the receipt and setup of the Plasma Welder for weld development; continuation of the Drywell Interaction Tests and the 2 kw Drywell Test; completion of the 2 kw Fuel Temperature Test and the 3 kw Soil Temperature Test; major overhaul of the Wall Mounted Handling System; installation of the major part of the Remote Air Monitor (RAM) System; and disassembly and packaging of the Reactor Maintenance, Assembly and Disassembly Building (R-MAD) windows.


Location-aware WSN applications are emerging from day to day life activities, exclusively in emergency use cases like disaster management, structural monitoring, patient monitoring, and security systems, etc. Estimation of sensor's location in WSN can be done using sensor nodes with install GPS, but it is very expensive, limited in outdoor applications, consume more power, and also increases the size of sensor nodes. Anchor/beacon-based localization is another way to estimate the location of the target/sensor node. Many of anchor-based localization algorithms are available to estimate the location of the target nodes. All available techniques have their limitations in the implementation to estimate the target node's location. In this paper, a novel anchor-based localization technique is proposed to estimate the target node's location more effectively and in this technique, one anchor node, and Angle of Arrival (AoA), RSS (Received Signal Strength) measures. AoA based vector segment can be derived in the proposed model and with the help of RSS based distance, the target node's location can be estimated. This technique is very simple to implement and the simulation results proved that the accuracy of the estimated coordinates of the target nodes is good.


This paper intends to review the need of cryptocurrency on the European and International market. Why cryptocurrency is bad and good at the same time for the international financial market is one of the main issues of this paper. Where are Bitcoin, Ethereum, Ripple, Bitcoin Cash, Litecoin going to and why cryp tocurrencies are necessary on today's market. Although there is no sure thing on crypto, on the long term, the market keeps going up and there is much interest in this direction.


To determine hydroxyl free radicals,a new method based on automatic potentiometric titration is founded and the relative parameters of lower detectable limit,precision and accuracy are measured.Also studied are the main influence factors and the concentrations of hydroxyl free radicals measured under the optimal experimental conditions which is compared with the result of the conventional oxidation-reduction titration.


The purpose of the invention is to provide: a fluorine-containing acetophenone derivative which is useful as an additive that is used to obtain a coating which imparts excellent antifouling properties and scratch resistance to a cured coating surface and has excellent transparency; a fluorine-based additive comprising the same; an active energy ray curable composition; a cured product thereof; and an article having a cured coating thereof. Specifically, the problem is solved by using the fluorine-containing acetophenone derivative which is represented by the following structural formula obtained by introducing an acryloyl group into a poly(perfluoroalkylene ether) chain, and then introducing, using a Michael addition reaction, an α-aminoacetophenone-based structural unit that can generate a radical species by photofission.


Brain activities have attracted considerable attention in medical and healthcare areas and engineering applications. Magnetoencephalogram (MEG) is a non-invasive technique for mapping and evaluating the functional activity of the brain. It is commonly measured by superconducting quantum interference devices (SQUIDs) which is the most reliable sensitive magnetometer for MEG measurement. However, the SQUIDs are still threatened by the need of cryogenic cooling liquids and a shielding room. For recording non-invasive cranial nerve activity, the technology with no liquid helium and high spatial resolution has been required for about 30 years. Sensitive micro-magnetic sensors referred to as magnetoimpedance (MI) sensors based on MI effect in thin amorphous magnetic wires are utilized as an electronics compass in a cellar phone. We have developed a gradiometer based on MI sensor for the purpose of biomagnetic field measurement. The gradiometer is composed of a pair of MI elements with 1 cm length each: a sensing element and a reference element with a baseline of 3 cm. The developed MI gradiometer has good linearity and a high sensitivity of $1.2 \times 105$ V/T with no amplification by semiconductor device. The noise level of the gradiometer is approximately 2 pT/Hz1/2. The MI sensor has system noise higher than SQUIDs, but it has considerable advantages that can measure closely to the scalp. Because of proximity measurement, the magnetic field from brain measured by MI sensor is larger than the case of SQUIDs. The precise MI gradiometer was tested as MEG detectors. The spontaneous brain activity (alpha rhythm) measurements were carried out on a female subject. As expected, the alpha rhythm signals simultaneously measured by electroencephalogram and MI gradiometer were significantly attenuated when the subject opens eyes and intensified with eyes closed. The subject's $\alpha $ wave MEG signal has a main frequency component of 10–11 Hz and the maximum amplitude is about 25 pT (effective value). Significant susceptibility of MI sensor to spontaneous brain activity was confirmed by signal-to-noise ratio of 8/1. In addition, the measurement of evoked magnetic field N100 was carried out in the unshielded environment. The measurement results about N100 in this paper are almost consistent with the previous study by SQUIDs.


Light rail operators could benefit from an advanced new system currently used by the bus industry to provide radio-based voice communication and reliable passenger information. Real-time passenger information (RTPI) produced by Tait Radio Communications is highlighted. RTPI has a number of key drivers: providing reliable information to the traveling public; providing detailed timetable adherence information to regulatory bodies; providing the precise location of a public transit vehicle at any given moment; and providing up-to-the-minute data via the Internet to customers. A study of the Tait system used by Dublin Bus is presented.


This paper presents an application of an acoustic signal characterization scheme for ocean acoustic tomography and geoacoustic inversions proposed by Taroudakis et al. [1], using real data. The work is the first attempt to validate the proposed scheme with data taken from sea experiments. The data have been collected during the SW06 experiment held in the New Jersey Continental Shelf and the inversion results (sea-bed geoacoustic parameters and source range) are compared with those reported by Bonnel and Chapman [2]. The comparison and the signal reconstruction using estimated values of the model parameters is satisfactory being an indication that the new signal characterization method can be used in practical applications of acoustical oceanography.


Spectral measurements provide a non-invasive and efficient means of mapping and monitoring vegetation species over large areas thanks to supervised classification. However, the presence of autocorrelation due to the incorporation of spatial or contextual information in the data can lead to overestimated classification performance and bias the assessment of the generalization power of the classification. This study evaluates this bias by comparing the performance obtained with different methods of training and testing data splitting at leaf and image levels for tree species classification. The average overall accuracies obtained from different data splitting methods differed by up to 30% for airborne image data (ranging from 68% with low correlation to 98% with high correlation) and 16% for field data (ranging from 80% to 96%). These differences demonstrate the need to consider the autocorrelation impacts for classification purpose.


AbstractThis research was motivated by the lack of experimental data concerning the complex flow fields produced by the USP Paddle Method Dissolution Test Apparatus, which influence the reproducibility and sensitivity of the resulting dissolution data.A one-component He-Ne fiber optics laser Doppler anemometer and a conditional sampling computer data acquisition provided unique three-dimensional fluid velocity measurements in most regions of the fluid inside the vessel. Tangential velocities which are predominant in magnitude decrease as a function of distance from the paddle to the liquid surface. Low magnitude circulation patterns in the axial direction exist with little Interaction between the fluid above and below the paddle. The radial velocity component also exhibits a low magnitude. In the vicinity of the paddle, a periodic fluid motion produced by the wake formed behind the paddle exists. Close to the bottom of the vessel, tangential fluid velocities were approximately equal to solid body rotation...


Since the collapse of the Soviet Union in 1991, Belarus has maintained a largely non-market economic system. This did not prevent rapid growth of its economy over a sustained period up to 2011. However, the period of economic growth in Belarus seems to be over. The factors that underpinned Belarus's growth, mainly the beneficial external environment, have gradually disappeared. As a result, the country is confronted by the need to...


Objective To investigate the effect of argon-helium cryoablation on immune function in patients with soft tissue sarcoma.Methods Thirty-six patients with soft tissue sarcoma were treated with argon-helium cryoablation.The levels of T-cell subsets of patients,such as CD3+,CD4+ and CD8+,CD4+/CD8+T cell ratio,were detected by flow cytometry before and one,two,and four weeks after cryotherapy,and serum IL-2,IL-4,IL-10 and IL-12 were analyzed by enzyme linked immunosorbent assay(ELISA).Thirty healthy persons served as normal controls.Results Before treatment,CD3+,CD4+ and CD4+/CD8+T cells,IL-2,IL-12 in the patients were lower than that in the control group(t=7.24-16.01,P0.01),and CD8+ T cells,IL-4,and IL-10 were higher(t=5.78-13.44,P0.01);after treatment,CD3+,CD4+ and CD4+/CD8+T cells,IL-2 and IL-12 increased(F=10.61-40.92,q=3.29-14.80,P0.05),CD8+T cells decreased(F=7.83;q=5.55,6.25,3.71;P0.05),and IL-4 and IL-10 were not changed significantly(F=0.95,1.06;P0.05).Conclusion The immune function in patients with tissue sarcoma is subnormal,Th1/Th2 subsets tend to drift to Th2.Shortly after cryoablation treatment,the immune function is up-regulated and Th1/Th2 subsets divert to Th1.


Open-access AI educational resources are vital to the quality of the AI education we offer. Avoiding the reinvention of wheels is especially important to us because of the special challenges of AI Education. AI could be said to be "the really interesting miscellaneous pile of Computer Science". While "artificial" is well-understood to encompass engineered artifacts, "intelligence" could be said to encompass any sufficiently difficult problem as would require an intelligent approach and yet does not fall neatly into established Computer Science subdisciplines. Thus AI consists of so many diverse topics that we would be hard- pressed to individually create quality learning experiences for each topic from scratch.


Modern apprenticeship is a personnel training mode adopted by today's western countries in vocational education. It aims to cultivate high-skilled talents who meet the requirements of enterprises and industrial structure. Centering on the task of accelerating the transformation and upgrading,constructing happy Guangdong,Guangdong are in urgent need of cultivating a group of high-skilled talents on a large scale,with reasonable structure and professional skills,so as to promote optimization and upgrading of the industrial structure and improve independent innovation ability. Through modern apprenticeship,enterprises and third-party institutions are able to actively participate in vocational education,which combines the efforts from both sides of higher vocational institutions and enterprises to effectively cultivate high-skilled talents.


Siberian sturgeon,Acipenser baerii,one of the oldest extant cold-water fish species in the world,are of considerable research and economic value.We documented the postembryonic development of the Siberian stur-geon by monitoring morphological characteristics and cell types in retina,taste buds,olfactory sac,and ampullary organs in the larvae.The stages of postembryonic development were defined based on both the external morphol-ogy and the internal organ characteristics.Larvae were reared at a water temperature of(18.0±1.0)℃ and a pH of 7.0?7.5.The newly hatched larvae(day 0) were(9.05±0.14) mm long.During the early-stages of development(days 0–7),the larvae were nurtured by a large yolk sac and the eye was the primary sense organ.The late-stage larvae(day 8?–22) were characterized by the disappearance of the yolk sac and initiation of active feeding,the formation of fins and fin rays,a shift in habitat use towards the bottom of the water column,and the completion of organ differentiation.As larvae reached the juvenile stage(day 23–57),the scutes begin to form,the organs tended to become fully developed,and the external morphology and body color pattern gradually matured into the adult pattern.We observed some differences in the development characteristics of the primary sensory organs in Sibe-rian sturgeon relative to other teleosts.Our observations suggest that Siberian sturgeon is an ancient species that occupy a unique position during the evolution of teleosts.


The National Ignition Facility, the world's largest laser system, was dedicated at a ceremony on May 29, 2009 at Lawrence Livermore National Laboratory. These are the remarks by Congresswoman Ellen Tauscher, of California's 10th district, which includes Livermore.


An Annotated Collection of Contracts Related to Social Life in Taiwan(台湾社会生活文书专辑) is an very valuable work about the history,society,economy and folk-custom of Taiwan in Qing Dynasty and Japanese Colonization.There are many mistakes of characters,words,and punctuations in the modern editions of this work.So,it's very necessary to collate this work again.


eywords: ntiretrovirals bacavir sulphate orced degradation degradation products were characterized by LC–MS/MS and its fragmentation pathways were proposed. No previous reports were found in the literature regarding the degradation behavior of abacavir sulphate. © 2010 Elsevier B.V. All rights reserved. C–MS/MS inetic behavior . Introduction Abacavir sulphate (ABC) (1S, cis)-4-[2-amino-6cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol ulphate (Fig. 1) is one of the nucleoside reverse transcriptase nhibitors (NRTIs) used to treat acquired immunodeficiency synrome (AIDS) caused by human immunodeficiency virus (HIV) 1], the activity of the drug is caused by the intracellularly formed arbovir triphosphate. Formulations of abacavir sulphate are sold nder the trade name of Ziagen for oral administration. Their tability is greatly influenced by varied environmental conditions uch as temperature, light and humidity. A very few reports are vailable in the literature on degradation of abacavir sulphate. A ew HPLC and LC–MS methods for the determination of abacavir ulphate in plasma, human serum and other biological matrices ere reported [2–4]. Simultaneous determination of abacavir ulphate and other antiretrovirals in pharmaceutical dosages as also carried out [5–11]. Seshachalam et al. have studied its orced degradation by HPLC [12]. However, neither the extent of egradation nor the characterization of degradation products was eported. The monograph published by World Health Organization WHO) reported six impurities, but their classification into process elated and degradation products was not described [13]. The omplete degradation profile of ABC and the mechanism of its egradation products are not yet reported in the literature. Tandem ∗ Corresponding author. Tel.: +91 4


The present invention has (a) a molecular formula The present invention is further to improve the stickiness to reduce and / or hydration effect of the composition, the use of molecular formula


High-resistance ground (HRG) systems have gained popularity in process applications due to their ability to continue operation after a single line-to-ground fault and to limit the escalation of a single line-to-ground fault to a multiphase event. Part I of the companion paper has set the guidelines for designing safe and reliable HRG systems on industrial power systems used with linear loads and the effect of increased line-ground voltage stress on motor loads during fault conditions. However, literature on characteristics and pitfalls of HRG systems when used with nonlinear power converter systems is limited. Part II investigates anomalies of HRG systems used with nonlinear power converters such as neutral voltage shifting, increased line-ground transient fault voltages for both motor and ac source terminals and their voltage compatibility issues, increased neutral grounding resistor power dissipation, susceptibility of ground fault sensing equipment to nuisance tripping, and dc-bus voltage resonance on faults. Part II also investigates HRG zero-sequence fault current characteristics and paths observed under various fault locations in a common ac or a common dc-bus pulsewidth-modulated adjustable speed drive (ASD) system. Part II concludes with a summary of application guidelines when using ASD HRG systems.


After excavations of the mound Arzhan-2, the main burial of which dates back to the second half of the 7th century BC, the scholars could not help but raise the question of the contacts of its creators with the civilizations of the Near East. In order to determine the main circle of contacts of Arzhan-2 in the Near East, it is necessary to summarize all the facts that may indicate the existence of such ties. The presence of coriander in the burial mound, as well as jewelry decorated with grain and enamel, made using the true cloisonne technique, proves that the connections of Arzhan-2 in the southwestern direction reached at least Western Iran.
The influence of the cultural traditions of Western Asia on the material complex of the Arzhan-2 mound was facilitated by the Sakas of the Aral Sea region. The discovery in the Sakar-chaga 3 burial ground bone sleeve with the image of two opposing wild boars, the closest analogies of which are found in the Arzhan-1 and Arzhan-2 mounds, and the Aramaic letters yod, he and waw, belonging to the last quarter of the 8th – 7th centuries BC, allows us to assert that the Sakas penetrated as far as the state of Mannea, in which the Aramaic script was used, and jewelry decorated with grain and cloisonne (a treasure from Ziwiye) are also known. Moreover, these campaigns could be made only before the formation of the Median kingdom at the end of the 670s BC.


Objective To explore the effect of different phleboclysis on acute pancreatitis patients. Methods One hundred and ten acute pancreatitis patients were randomly divided into traditional infusion group, micro-pump 24 hours continuous infusion group and 12hours continuous infusion group. The therapeutic effect, adverse reactions, the degree of satisfaction, average length of stay were observed. Results ① The therapeutic effect had no significant difference between micro-pump group and traditional group ( P > 0. 05 ) .Adverse drug reaction in micro-pump groups were significantly lower than that in traditional group ( P <0. 01 ) . The degree of satisfaction in micro-pump groups were significantly higher than that in traditional group ( P < 0. 05 ) . ②The therapeutic effect and adverse drug reactions had no significant different between the 12 hours pump group and 24 hours pump group (P > 0. 05 ) . The degree of satisfaction in 12hours pump group was higher than that of 24 hours pump group (P <0. 05) . ③The average length of stay were 18 d, 16 d, 12 d in traditional group, 24 hours pump group and 12 hours pump group respectively. Conclusions 12 hours pump group is superior to other groups, it can shorten the length of hospital stay, reduce the patients' financial burden, expand social benefits.

Key words:
Micro-pump; Somatostatin; Acute pancreatitis


In vitro cultural systems of medical plant, A. belladonna was established, bacteria-free leaves were used as explants for genetic transformation by A. rhizogenes strain A4. The result showed that all the infected leaves could produce hairy roots from the wound sites. The hairy roots shown a typical phenotype characterized by plagio-tropic growth, high incidence of lateral branching and faster growth than untransformed roots in phytohormone-free medium. PCR analysis showed that the rooting genes including rolB and rolC were confirmed integrated into the genome of A. belledonna hairy roots. Three root lines were investigated for growth rate and alkaloid productivity after cultured in liquid MS medium 35 days, the maximum biomass of hairy roots increased up to 7. 5 times. The maximum amount of hyoscyamine (5. 61 mg · g-1) was present in the hairy root lines T6, which had almost 7 times than that recorded in untransformed mature plant roots (0. 84 mg · g-1) , the maximum amount of scopolamine (2. 35 mg · g-1) was present in the hairy root lines T2, which had more than 9 times than that recorded in mature plant roots (0. 25 mg · g-1). Results revealed that the rol genes seemed sufficient to induce the hairy root phenotype, including fast growth rate and a high level of secondary metabolite accumulation. This work shows that hairy root culture of A. belladonna. is a good way to produce tropane alkaloid.


The invention discloses a skin occlusion outer fixing bracket. The skin occlusion outer fixing bracket comprises a threaded flat rod, a pair of sliding side blocks, a pair of sheet nuts, a plurality of Z-shaped bone spicules and two springs, wherein the pair of sliding side blocks is arranged on both sides of the threaded flat rod in a sleeving way; the pair of sheet nuts is screwed at the two ends of the threaded flat rod and corresponds to the sliding side blocks one by one; the two springs are arranged on the threaded flat rod in a sleeving way and are connected with corresponding sliding side blocks and sheet nuts respectively; the heads of the two Z-shaped bone spicules are relatively fixed on opposite sides of the two sliding side blocks respectively. During use of the skin occlusion outer fixing bracket, skin or soft tissues are prevented from being cut, so that secondary harm is avoided.


During the Covid-19 pandemic, it was found that the health certificates needed by many people for traveling outside the city as a requirement in preventing transmission of this virus were falsified. The crime of forging letters is a crime that is quite common in society during a pandemic. This study aims to examine the criminal act of forging a rapid test certificate as a condition for traveling out of town during the Covid-19 pandemic, against the background of the problem of how to regulate the criminal act of forging a medical certificate and the sanctions imposed on perpetrators of the crime of forging a rapid certificate. the Covid 19 test, and how law enforcement efforts to regulate the criminal act of falsifying medical certificates. The research method used in writing this thesis is descriptive, analysis leads to normative juridical, namely a material other law. This study uses library research techniques (Library Research). The analysis was carried out qualitatively. This research is an answer to the background of the problem related to the crime of forging a rapid test letter as a condition for traveling out of town during the Covid-19 pandemic. One form of law enforcement efforts to curb the criminal act of forging medical certificates is in one of the cases of forging rapid test certificates described in this study, in which the perpetrator was sentenced to 1 year and 10 months in prison by the Panel of Judges at the Pangkalan Bun District Court. The case above is a form of law enforcement against the act of making fake letters of the results of the Covid-19 rapid test.


The issue of creating a system for modeling the processes taking place inside medical organizations is very complex and time-consuming. Multi-agent systems (MAS) based on fuzzy rules are often used to solve it. With MAS you can simulate the flow of patients, the work of staff and specialized equipment, but the creation of such systems requires special knowledge and skills. The result of this work is an algorithm for the step-by-step construction of such systems: from the technical formulation of the problem to the choice of the software environment.


We investigated the spin-dependent transport properties of a lateral spin-valve device with a 600 nm long GaAs channel and perpendicularly magnetized MnGa electrodes. Its current–voltage characteristics show nonlinear behavior below 50 K, indicating that tunnel transport through the MnGa/GaAs Schottky barrier is dominant at low temperatures. We observed large magnetoresistance (MR) ratios up to 12% at 4 K when applying a magnetic field perpendicular to the film plane. Furthermore, a large spin-dependent output voltage of 33 mV is obtained. These values are the highest in lateral ferromagnetic metal/semiconductor/ferromagnetic metal spin-valve devices.


Relaxed, high-quality, compositionally step-graded InAsyP1−y layers with an As composition of y=0.4, corresponding to a lattice mismatch of ∼1.3% were grown on InP substrates using solid-source molecular-beam epitaxy. Each layer was found to be nearly fully relaxed observed by triple axis x-ray diffraction, and plan-view transmission electron microscopy revealed an average threading dislocations of 4×106 cm−2 within the InAs0.4P0.6 cap layer. Extremely ordered crosshatch morphology was observed with very low surface roughness (3.16 nm) compared to cation-based In0.7Al0.3As/InxAl1−xAs/InP graded buffers (10.53 nm) with similar mismatch and span of lattice constants on InP. The results show that InAsyP1−y graded buffers on InP are promising candidates as virtual substrates for infrared and high-speed metamorphic III–V devices.


Two new structurally similar molybdenum(VI) complexes, [MoO2L1(CH3OH)] (1) and [MoO2L2(CH3OH)] (2), where L1 is the dianionic form of N′-(2-hydroxy-5-nitrobenzylidene)-2-methylbenzohydrazide and L2 is the dianionic form of N′-(2-hydroxy-4-methoxybenzylidene)-2-methylbenzohydrazide, were prepared and structurally characterized by elemental analysis, infrared spectra, and single-crystal X-ray diffraction. 1 crystallizes in the monoclinic space group P21/c, with unit cell dimensions a = 7.941(1), b = 14.337(2), c = 15.141(2) Å, β = 92.782(2)°, V = 1721.8(4) Å3, Z = 4, R1 = 0.0286, wR2 = 0.0650, GOOF = 1.028. 2 crystallizes in the triclinic space group P-1, with unit cell dimensions a = 8.003(1), b = 10.608(1), c = 10.880(1) Å, α = 95.745(2)°, β = 97.627(2)°, γ = 105.762(2)°, V = 872.0(2) Å3, Z = 2, R1 = 0.0226, wR2 = 0.0595, GOOF = 1.116. X-ray analysis indicates that Mo in the complexes are coordinated by the phenolate oxygen, imino nitrogen, and enolate oxygen of the benzohydrazone, methanol, and two oxo groups, generating octahedral coordination. The oxidation of olefins with the complexes as catalysts was evaluated, indicating that the complexes showed excellent catalytic efficiency in oxidation of most aliphatic and aromatic substrates under mild conditions using tert-butyl hydrogen peroxide as oxidant. Graphical Abstract


The variable-speed electrohydraulic drive has been applied in hydraulic machines having power matching means. However, further development has been restricted by its slow response and poor low-speed behavior. Owing to these disadvantages, a novel drive principle comprising a variable-speed valve-controlled-motor drive with an accumulator-based power assisted unit (PAU) is proposed. The PAU is an energy assisting and recycling device, which can release or absorb hydraulic energy according to the system's requirements. With the aid of PAU, the proposed drive is expected to improve response and control precision compared with the variable-speed drive. The proposed drive principle system is a multi-input-multi-output (MIMO) complicated nonlinear system with time-varying, which increases the control difficulty. A mathematical model of the proposed drive was first derived then a hybrid control strategy was presented. The dynamic simulations of three traditional drives and the novel one were performed using AMESim-Simulink co-simulation models. The four drives have been tested using three common variable-load disturbances. Comparisons of simulation results show that the proposed drive principle system demonstrates a good dynamic performance, which can not only achieve the expected energy saving target, but also significantly improve the response and control precision over the existing variable-speed drive system.