Objectives: More and more referrals to memory clinics are expected, but diagnostic routes are already challenged. In order to be able to follow the advice to diagnose dementia more often and earlier in the process, but also to be able to handle the increasing numbers of referrals, a fast but reliable triage test is needed. According to the Cochrane review, "the MoCA can help identify people who need specialist assessment and treatment for dementia". It has been validated in multiple institutions and languages. However, many of these studies are designed with a case-control design using healthy, community-based individuals as controls, which can lead to spectrum bias. Our cohort of referrals to a memory clinic with patients suspected of having cognitive disorders (mild dementia and MCI) after initial assessment in an old age psychiatric clinic, needs to be validated because different settings can give different results. Design: our reference standard consisted of a consensus-based diagnosis according to international criteria for detecting MCI and MD, and this was compared with patients suspected of MCI/MD - but excluded from cognitive disorders (NoCI)- from the same cohort. Results: The mean MoCA scores differ significantly between the groups: 24 in NoCI, 21 in MCI and 16.5 in MD. The AUC of MD against non-demented (MCI+NoCI) was 0.83 resulting in 90% sensitivity, 65% specificity, 50% PPV and 94% NPV at a best cut-off of <21 according the Younden index. For CI (MD+MCI) against NoCI the results were respectively 0.77AUC, 95%sens, 47%spec, 88%PPV, 68%NPV at a cut-off <26. On an individual basis, as a box plot of DSM IV diagnoses showed, the MoCA score has limitations and clinical aspects need to be taken into account: FTD, high education to the upside; MCI including psychiatric etiology to the downside. Conclusions: by using a cut-off score of <21, 90% of people with positive MoCA have CI, while 94% of people with negative MoCA (≥21) will not have dementia. The MoCA can significantly reduce referrals (50%) by excluding patients for further diagnostic work-up at a memory clinic, even if they are suspected of CI after initial assessment.


Along with the constant development of the Internet,XML,a half structural language,has gradually become an important data carrier.Many applications and services are using XML as an object of data transmission,so the safety of XML data becomes very important.In this case,according to various kinds of a variety of strategies and models arise in accordance with at XML data safety.This paper,from the logical perspective,puts forward several analysis methods,namely,compulsory logic,validation and influence of changes.


Controversial features of REA divide AIS educators on the virtues of teaching REA versus traditional AIS models. Some educators on both sides of the issue consider REA and traditional AIS to be mutually exclusive propositions. This article demonstrates that REA is an evolutionary rather than revolutionary concept that is rooted in traditional AIS models. The article examines the evolutionary relationship between REA and the manual process, the flat-file, and the data base models. The article shows that REA and traditional AIS can and should share the same podium. In fact, a sound appreciation of REA principles follows from insight gained by studying and understanding traditional AIS models. The appendix to the article presents a strategy for teaching REA within the structure of a traditional AIS course.


A new sesquiterpenoid coumarin, marmaricin, C24H30O4, was isolated from the roots of Ferula marmarica L., grown in Egypt. The carbon skeleton of the sesquiterpenoid moiety was identified by selenium dehydrogenation, yielding 1, 2, 5, 6-tetramethylnaphthalene. The coumarin moiety was determined by acid cleavage to give umbelliferone. The structure of marmaricin was assigned on the basis of spectral and chemical evidence.


The paper describes experiment devoted to the field reversal in a mirror trap with neutral beam injection, which is planned for realization now in Budker Institute. The technical details of experimental device and expected plasma parameters are discussed. In accordance with theoretical predictions, parameters of experimental facility (neutral beam current − 240 atom A, energy of neutrals − 15 keV, magnetic field − 0.2 T, electron temperature 50 eV and target plasma density ∼1013−1014 cm−3) are expected to be sufficient to field reversal in the case, if anomalous ion losses are not essential.


with a history of arterial hypertension and dyslipidaemia, was admitted to our department for a scheduled coronary angiographic examination. Two months before entry, the patient had been admitted to another hospital for an extensive anterior myocardial infarction, treated with intravenous thrombolysis. The coronary angiogram recorded one week after the acute infarction depicted an ulcerated atheromatous plaque in the left main coronary artery, along with subtotal occlusion of the left anterior descending artery in its proximal part, and non-significant stenoses in the (dominant) circumflex, one before the origin of the first obtuse marginal branch and another in its peripheral part. The right coronary artery was a small vessel without stenoses, while left ventriculography showed akinesis of the anterior wall of the left ventricle, with an apical aneurysm and severely impaired contractility (ejection fraction ~30%). A cardiac surgical evaluation, requested by the treating cardiologist, recommended conservative treatment, given that the residual lumen and the flow in the left main coronary artery were very satisfactory. During the postinfarction period the patient reported exertional dyspnoea and moderate fatigue, without, however, typical anginal discomfort. The echocardiographic examination revealed akinesis and thinning in the region supplied by the left anterior descending artery, while a dobutamine stress echo test showed no viability in that region, nor any evidence of ischaemia in the other myocardial territories, during infusion of maximal dobutamine dose. A coronary angiographic examination was then performed for re-evaluation of the atheromatous plaque in the left main coronary artery and again showed a crater-like formation in the middle part of the vessel, communicating with the lumen via a thin stem (Figures 1, 2). The dimensions and morphology of the structure did not differ from the previous angiogram, while its external boundary, on cine-angiography, was seen to be a continuation of the adventitia of the left anterior descending artery, a finding strongly suggestive of an ulcerated atheromatous plaque. The left anterior descending artery, in contrast to the initial study, was patent, with a stenosis of approximately 85%, while the findings in the remaining vessels were unchanged. From a comparative study of the two successive angiograms we speculated that rupture of the atheromatous plaque in the main coronary artery had contributed to the complete embolic occlusion of a critically stenotic left anterior descending artery, which on the second angiogram, as stated above, was patent although stenotic.


Volume reduction surgery has recently been an important surgical procedure for patients with severe pulmonary emphysema. We compared the sagittal and coronal images taken by the HASTE sequence with those obtained by turbo FLASH during deep breathing and with CT images obtained under deep inspiration. Clear images were obtained from both sequences, without cardiac or respiratory motion artifacts. The emphysematous areas were demonstrated as low signal intensity areas, as in CT images. The ratio of signal intensity in the expiratory phase to that in the inspiratory phase was lower than that of volunteers in the HASTE sequence. The HASTE sequence provides useful information about respiratory movement as well as about changes in the pulmonary parenchyma when used for preoperative examination.


In this work, we communicate the issue of Lie algebroids. More precisely, we discuss the subject based on the generalized Stieltjes fractal-like approach of the calculus of variations. We derived the corresponding Euler-Lagrange, geodesics and Wongs equations and we illustrate then, by discussing, the resulted dynamics of a colored particle in Yang-Mills. Many motivating consequences are explored in particular, the emergence of complexified Lie algebroids with its corresponding complexified Lagrangian and Hamiltonian dynamics from the fractal approach.


Objective To predict protein transduction domain (PTD) which is a short peptide with the ability to pull diverse molecules across cell membranes.Methods Every peptide segment including PTDs and peptide sequence from SwissProt database was represented by 68 numerical values,which reflected their physicochemical and conformational properties related to the PTD' s membrane penetrating function.Transductive support vector machine (TSVM) and support vector machine(SVM),combined with cluster method,was introduced to predict new PTDs from the peptide segments,which were extracted from SwissProt database.Results TSVM prediction model achieved 94%±4% accuracy and SVM model achieved 94%±5% accuracy.1210 possible PTDs were predicted using the classifiers based on these two models.Conclusion The research provides a guide to find more PTDs in molecular biology experiments and will be helpful in the understanding of the mechanism of PTDs and their function in vivo.

Key words:
Protein transduction domain;  Support vector machine;  Prediction;  Bioinformatics


Ekvall's Cultural Relations on the Gansu-Tibetan Border serves as valuable historical materials for the study of early protestant dissemination and ethnic relations in broad Gannan district(southern Gansu).No sufficient or systematic introduction has been made to it in China.In anthropological perspective the book explores the ethnic and cultural relations of Gannan district in the early 19th century,Chinese,Chinese-speaking Moslems,Nomadic Tibetans,Sedentary Tibetans with emphasis on the cultural relations among the four ethnic types-Chinese and Chinese-speaking Muslims;Chinese and Sedentary Tibetans;Muslims and Nomadic Tibetans;Nomadic Tibetans and Sedentary Tibetans.By introducing the contents of the book the paper mainly presents the foreign missionary's view on the cultural relations in Gannan district and then attempts to probe into the cultural theoretic value.


Aortic arch aneurysms have always been difficult cases to perfuse. Most reports describe the use of several pump heads to perfuse different arterial trees. (1 ,2,3) A technique de scribed by Pearce, (4) uses one arterial pump head to perfuse all necessary arterial branches (Fig. 1 ). This case report emphasizes this technique for resection of a distal arch an eurysm. A


Modifications in the structure and composition of anodic silicon oxide film during the dielectric breakdown process have been studied by infrared spectroscopy (IR) and XPS. Before breakdown, the IR spectrum of the anodic silicon oxide film shows the band associated with the asymmetric stretching transverse mode of the SiO4 tetrahedra. However, after dielectric breakdown, apart from the strongest SiO band, carbon incorporation in the silicon oxide film is detected in the form of new bands as SiOC, CC, C=O and CH.

Scanning electron microscopy observations show that the breakdown process is initiated in the form of islands consisting of pores and cracks randomly distributed across the otherwise flat surface of the silicon oxide. Energy-dispersive x-ray analysis in the damaged zones confirms the presence of carbon, which is attributed to the incorporation of carbon species from the organic electrolyte. After prolonged breakdown the cracks and pores cover the whole surface of the sample.

In-depth XPS and IR analyses indicate that the breakdown areas have a layered structure. In all cases the inner layers, close to the substrate, are composed of silicon oxide, while the composition of the outer layers depends on the breakdown time: for short breakdown times a layer of SiOxCymaterial is formed, which is similar to a silicate rather than an oxycarbide structure. The Auger parameter of silicon obtained from XPS core-level and Auger electron energies is smaller than those of the oxides and carbides of silicon but coincides with those of silicates, suggesting also an open structure for the SiOxCymaterial. For long breakdown times an amorphous carbon outer layer is also detected. © 1997 by John Wiley & Sons, Ltd.


GEOLOGY AND HYDROCARBON POTENTIAL OF THE BARNETT SHALE (MISSISSIPPIAN) IN THE NORTHERN DELAWARE BASIN, WEST TEXAS AND SOUTHEASTERN NEW MEXICO By Travis J. Kinley, M.S., 2006 Department of Geology Texas Christian University Dr. John Breyer – Professor of Geology Dr. Richard Hanson – Professor of Geology and Department Chair Lance Cook – Manager, Rocky Mountains, Geology, XTO Energy The Barnett Shale (Mississippian) in the Delaware basin has the potential to be a prolific gas producer. It is organic-rich and thermally mature over large portions of the basin. Depths to the Barnett range from 7,000 feet (2,333 meters) along the western edge of the basin to more than 18,000 feet (6,000 meters) along the basin axis. The Barnett Shale began generating gas 250 Ma ago and remains in the gas window to this day. The shale can be divided into an upper clastic unit and a lower limy unit by changes in resistivity. The lower unit can be subdivided into five subunits by distinctive well-log markers. Preliminary analyses suggest that intervals in the lower Barnett marked by high resistivity and high neutron porosity readings on well-logs have high gas contents. Areas in which to focus future exploration can be delineated by mapping net-resistivity greater than 50 ohmm in the lower Barnett.


Weighted node scheduling technique assigns weights to servers based on their serving capacities. To measure servers' serving capacities, the preferred attribute from a set of attributes is chosen. In order to distribute the request to servers, it is necessary to determine the allocation share for each server. In this research, the allocation share is decided in terms of the servers' serving capacities based on the most preferred attribute already chosen from Conjoint Analysis. A statistical method called Z-Score is used to do this. This chapter discusses the following in detail.


Magnetic beads enriched method was used to isolate microsatellite DNA from Leuciscus waleckii Dybowski genome.L.waleckii genomic DNA was extracted and then digested with restriction enzyme Sau 3A I.Targeted segments of 400-900 base pairs were collected by centrifugation of sucrose density gradient and ligated to adaptors.Then the purified ligated DNA was hybridized with Biotin-labeled simple sequence repeats probes(CAG)8,(TGA)8,(AGAT)6 and(GATT)6.After capture of target fragments by magnetic beads and PCR amplification,the selected DNA s were cloned into the pMD18-T vector and transformed into competent Escherichia coli DH 5α,and finally a microsatellite library was obtained.One thousand,four hundred and sixteen positive colonies were obtain through twice screens by colony PCR.Sequencing of these positive colonies confirmed that 1 047 contained microsatellite loci(number of repeats ≥5).Among these sequences,737 repeat motifs(about 67.99%)were perfect,166 repeat motifs(about 15.31%)were imperfect,and 181 repeat motifs(about 16.70%)were compound.We design 105 pairs of primers from 160 microsatellite sequence and compose them.As a result,56 pairs were screened and used successfully to amplify special fragment,among which 23 pairs were polymorphism.Using 18 pairs of these microsatellite markers,we analyzed genetic structures of one L.waleckii population sampled from Dali Lake.The result showed that the alleles were ranged from 3-11,while the polymorphic information content(PIC)were 0.207 7-0.882 0.The statistic results indicated that 67%loci(12/18)were in high polymorphic level.


This paper focus on the real situation of a countryside school to culture the futuristic local P.E. teachers. By using the methods of investigating and analyzing, the author gave a study onto the equipments and sport fields, the works of P.E teachers in countryside schools and the manner that local governments officers treat to those schools and teachers who are teaching P.E. courses here.and pot forward that teaching to thought and moral education must be strengthen and give some concrete measures as well as the teaching reformation methods of culturing working and creative ability.


Background: Neoadjuvant chemoradiotherapy (CRT) followed by an esophagectomy is the standard treatment for locally advanced esophageal cancer, but remains a great challenge for elderly patients. Therefore, we aim to evaluate the efficacy of definitive CRT in elderly patients with esophageal cancer. Methods: From December 2007 to October 2017, 40 esophageal cancer patients aged ≥70 years receiving definitive CRT were retrospectively analyzed. All patients received cisplatin-based chemotherapy. Ten patients received standard doses of cisplatin 20 mg/m2 and fluorouracil (5-FU) 800 mg/m2 for 4 days, during the first and fifth weeks of radiotherapy. Eighteen patients received modified doses of cisplatin 16 to 18 mg/m2 and 5-FU 600 to 800 mg/m2. Twelve patients received lower doses of cisplatin 10 to 12 mg/m2 and 5-FU 400 to 600 mg/m2. The endpoints were overall survival (OS), tumor response rate, and treatment compliance. Results: The 3-year OS rate was 28.8% The 3-year OS rates for patients receiving standard, modified, and lower doses were 12.5%, 53.8%, and 0.0%, respectively (p = 0.05). There were 87.5% of patients completing the scheduled radiotherapy dose, along with two cycles of concurrent chemotherapy. The response rate (clinical complete response and partial response rate) was 70.0%. Multivariate analysis revealed that no statistical difference was found in the OS among three groups of chemotherapy dosage. The treatment response was the only independent prognostic factor to OS (p < 0.001). Conclusion: Definitive CRT with dose modification is a feasible, safe, and reasonable treatment for elderly esophageal cancer patients. Achieving a better compliance to CRT via an optimal dose modification of chemotherapy may provide better clinical outcomes and would be the treatment goal for elderly esophageal cancer patients.


For decades, the education system has struggled to serve Latinx students, viewing them in a way that focuses on their deficits. However, Latinx scholars have proposed a series of asset-based frameworks to reframe and reshape how we see and treat Latinx students in the U.S. system. Using the Dora the Explorer's mochila (backpack) as a metaphor to capture the assets Latinx students bring to the classroom, Louie Rodriguez proposes that teachers think of Latinx students as carrying mochilas of excellence into the classroom. This framing encourages educators to recognize and develop Latinx student agency and help them realize the power and promise of education in their lives.


Knowledge management is essential to work sustainably and efficiently. From the tacit knowledge of persons who can learn and exchange information with each other, it will be used to create explicit knowledge for exchanging and integrating to work effectively in the future. Based on this approach, we created an approach to enhance medicinal plants' knowledge management skills through personalized learning. By using integrated information of medicinal plants as a model for teaching knowledge management, a tool to record personalized learning requirements for students had been developed. The tool was able to choose the learning styles, languages used in reports, and methods of assessments. It was applied to 167 second-year pharmacy students in the Faculty of Pharmacy, Silpakorn University, who enrolled in the course, namely, Informatics for Health Professional, on the topic of knowledge management at the end of the academic year 2019. The students were assigned to use information technology to manage the knowledge of medicinal plants. Collecting reliable information will be recorded in the KUIHerbRx2020, a tool for collecting herb information. The results showed that the students could search for reliable herbal information and transfer them into the KUIHerbRx2020. The students were also satisfied with the personalized learning. They received higher overall scores than previous year students. With this approach, the development of knowledge management skills and techniques in personal learning can be applied to other teaching and learning topics.


The invention provides a caster device of a baby stroller. Each caster device comprises a caster, a sleeve shell and a wheel arm; the upper and lower opposite ends of the wheel arm are respectively and rotatably pivoted with the sleeve shell and the caster; the sleeve shell comprises a first pressing part; the wheel arm comprises a second pressing part which is spaced with the first pressing part; the caster device further comprises an elastic element which abuts between the first pressing part and the second pressing part; as the caster drives the wheel arm to rotate relative to the sleeve shell, the distance between the second pressing part and the first pressing part is shortened and the elastic element is compressed, so that the elastic element can effectively absorb the vibration force of the caster, and the smoothness when the baby stroller moves can be improved.


Recent technological development has made single cell assays, e.g., single-cell RNA sequencing (scRNA-seq), reach unprecedented scale and resolution in revealing cellular heterogeneity. There is an increasing appreciation of the extent of intrinsic cell-to-cell variability in gene expression or single cell expression variability (scEV). However, whether this variability per se is functionally important and its implications to multi-cellular organisms remain unclear. Here, we analyzed multiple scRNA-seq data sets generated from lymphoblastoid cell lines (LCLs), lung airway epithelial cells (LAECs), and dermal fibroblasts (DFs). For each of the three cell types, we estimated scEV in homogeneous populations of cells and identified 465, 466, and 291 highly variable genes (HVGs), respectively. These HVGs are enriched with specific functions precisely relevant to the cell types, from which the scRNA-seq data used to identify HVGs are generated— e.g., HVGs identified with lymphoblastoid cells are enriched with those involved in the cytokine signaling pathways, LAECs collagen formation, and DFs keratinization. A number of HVGs are co-regulated by common transcription factors, and, thus, co-expressed, showing coordinated transcriptional outbursts across cells. We also found that scEV is a heritable trait, partially determined by genetic makeups of the donors of the cells. Furthermore, across genes, especially immune genes, the level of scEV is positively correlated with that of between-individual variability in gene expression, suggesting a potential link between the two variabilities measured at different organizational levels. Taken together, our results support the "variation is function" hypothesis, emphasizing the idea that scEV is required for higher-level system function. Assessing and characterizing scEV in relevant cell types may deepen our understating of pathological cell processes.


A method for generating a plant with a shorter rest period as compared to the from naturally occurring plant of the same species by increasing an intracellular 2-OG content in plants comprising the step of overexpression of an intracellular GDH gene in the plant.


The 1H and 13C NMR resonances of ten bicyclo[4.3.0]‐ and bicyclo[6.3.0]‐γ‐lactones and α‐carbomethoxy‐γ‐lactones were completely and unambiguously assigned by a combination of homonuclear (gs‐COSY), 1H‐detected heteronuclear one‐bond (gs‐HMQC) and long‐range (gs‐HMBC) gradient‐selected correlation experiments. © 1998 John Wiley & Sons, Ltd.


Extracellular ATP and other nucleotides act through specific cell surface receptors and regulate a wide variety of cellular responses in many cell types and tissues. In this study, we demonstrate that murine mast cells express several P2Y and P2X receptor subtypes including P2X 7 , and describe functional responses of these cells to extracellular ATP. Stimulation of bone marrow-derived mast cells (BMMC), as well as MC/9 and P815 mast cell lines with millimolar concentrations of ATP, resulted in Ca 2 (cid:1) influx across the cellular membrane and cell permeabilization. Moreover, brief exposures to ATP were sufficient to induce apoptosis in BMMCs, MC/9, and P815 cells which involved activation of caspase-3 and -8. However, in the time period between commitment to apoptosis and actual cell death, ATP triggered rapid but transient phosphorylation of multiple signaling molecules in BMMCs and MC/9 cells, including ERK, Jak2, and STAT6. In addition, ATP stimulation enhanced the expression of several proinflammatory cytokines, such as IL-4, IL-6, IL-13, and TNF- (cid:2) . The effects of ATP were mimicked by submillimolar concentrations of 3- O -(4 (cid:1) -benzoyl)-benzoyl-benzoyl-ATP, and were inhibited by pretreatment of mast cells with a selective blocker of human and mouse P2X 7 receptor, 1[ N,O -bis(5-isoquinolinesulphonyl)-N-methyl- L -tyrosyl]-4-phenylpiperazine, as well as oxidized ATP. The nucleotide selectivity and pharmacological profile data support the role for P2X


We propose a new obstacle avoidance method for mobile robots in unknown and dangerous environments. The method involves scanning the environment with a laser radar to obtain map data and building a grid map environment model, followed by initial path planning using an improved A* algorithm. To address the shortcomings of the A* algorithm, such as paths that are too close to obstacles and large turning angles, we propose combining the A* algorithm with an improved artificial potential field method. This method establishes a repulsive field between the robot and obstacles, ensuring that the robot's motion path stays away from obstacles. Simulation experiments have demonstrated that the obstacle avoidance mobile robot has excellent motion control capabilities.


Monopolization enterprise can obtain super profit with monopoly power, and internal department can produce interests as well. Therefore each department will seek rent for the interests, which make the Institutional environment worsen. The internal control can't have an effect due to the high costs of implementation and the cultural difference between china and Western countries. Decreasing rent by technology method can further define the property right, increase the economic efficiency, and decrease the rent-seeking phenomenon efficaciously on condition of the price discrimination.


Abstract : This study aimed to analyze the effect of asset security, data integrity,
effectiveness of achievement of organizational goals and resource efficiency of student
behavior. The research method used is multiple linear regression to see the influence of
variables in the study variables. The study population are students of Information Systems
and the sample are students who are taking semesters four or more. The number of
samples in this study were 100 samples determined by purposive random sampling
technique. The results showed a significant effect among all variables simultaneously or
simultaneously and partially to the student behavior variables. Linear regression model
equation generated was Y = 0712 + 0.637X1 + 0.204X2 + 0.237X3 + 0.182X4 + e
Keywords: Audit, Information Systems, Asset Security, Data Integrity, Effectiveness,
Efficiency Resources, Student Behavior


Two deoxyribonucleases have been demonstrated in cell-free extracts of rat intestinal mucosa. The enzymes were separated by ion-exchange chromatography on DEAE-cellulose and further purified by partition on hydroxyapatite. One DNase had optimum activity at pH 6.8–7.0 in ammonium acetate buffer, required Mn2+ or Mg2+ for activity, and was inhibited by EDTA. This enzyme is a DNase I by Laskowski's criteria Advan. Enzymol. 29, 165 (1967). The second enzyme was a DNase II with optimum activity at pH 3.5–4.0 in sodium formate buffer, was not inhibited by EDTA, and showed no requirement for divalent cations. Both enzymes were active only with native DNA and had no action on heated DNA or purified yeast transfer RNA.


1. The principles of equity 2. The nature of the trust 3. The settlor: certainties and formalities 4. The beneficiary's rights 5. The trustees' duties 6. Resulting trusts 7. Constructive trusts 8. Equitable estoppel 9. Trusts of land and of the home 10. Breach of trust, strangers and tracing 11. Quistclose trusts and Commercial trusts 12. Charities 13. Injunctions and other Equitable remedies 14. Themes in equity


The excited-state relaxation dynamics of a D-π-A sulfonium-based alkoxystilbene photoacid generator has been investigated in acetonitrile solution by using femtosecond transient absorption and nanosecond laser flash photolysis experiments. For the first time, the successive reaction steps involved in the photoinduced proton generation of a sulfonium acid generator have been kinetically and spectrally resolved from the early stages (femtosecond time scale) to the final chemical processes (microsecond domain). An overall four-step reaction scheme is established, and two main deactivation pathways limiting the proton generation efficiency are identified and quantified.


In the present study, we examined the expression of interleukin 2 (IL- 2) receptors on normal human B cells as well as established B cell lines. Anti-Tac monoclonal antibody did not bind to freshly separated normal human B cells. Unexpectedly, with the appropriate activation of the normal B cells by anti-mu antibody, phorbol myristate acetate, or Staphylococcus aureus Cowan I (SAC), Tac antigen was induced on the activated B cells. Anti-Tac antibody showed consistent reactivity with two B cell lines that were infected by human T cell leukemia virus (HTLV) and some reactivity with two out of eight Epstein-Barr virus- transformed B cell lines established from normal adult donors. Immunoprecipitation analysis revealed that antigens of similar size with a molecular weight of 50,000-60,000 can be precipitated with anti- Tac antibody from phytohemagglutinin-stimulated normal T cell blasts and normal activated B cells, as well as a cloned B cell line. Binding assays of IL-2 on normal activated B cells and on the cloned B cell (HS1) revealed that B cells have significantly fewer sites and lower- affinity IL-2 receptors compared with phytohemagglutinin-stimulated normal T cell blasts. Finally, biological properties of the IL-2 receptor on B cells were examined by incubating B cells with recombinant IL-2. It was found that moderate concentrations of IL-2 induce significant enhancement of proliferation and differentiation in SAC-activated normal B cells. These results suggest that normal B cells may express functional IL-2 receptors or closely related proteins and thus IL-2 may play a significant role in the modulation of B cell function.


Ammonia is the primary gaseous alkaline species in the atmosphere over Europe, neutralising up to 70% of the original acidity in precipitation [Buijsman et al., 1987]. It is directly involved in the conversion of sulphur dioxide and nitrogen oxides into the aerosol phase. Furthermore, ammonium contributes considerably to the nitrogen deposition and soil acidification which causes extensive changes in plant communities in many ecosystems [Moore, 1995 ; Rohde et al., 1995]. However, in Europe continuous long-term measurements of atmospheric ammonia or ammonium in precipitation are lacking. Here, we present a continuous, high-resolution record of ammonium in precipitation for the time period 1780 to 1980 deduced from an ice core recovered from a high-altitude glacier in the Alps. The ammonium level remained constant from 1780 to 1870 and increased afterwards by a factor of three. This trend shows that ammonia emissions in Europe have substantially increased in the last 100 years.


This note summarizes the consensus that is emerging and describes the sorts of analyses that will prove critical in seeking or opposing the certification of a particular class.


Quantum mechanics provides an exact description of microscopic matter, but predictions require a solution of the fundamental many-electron Schrödinger equation. Since an exact solution of Schrödinger's equation is intractable, several numerical methods have been developed to obtain approximate solutions. Currently, the two most successful methods are density functional theory (DFT) and quantum Monte Carlo (QMC). DFT is an exact theory which, which states that ground-state properties of a material can be obtained based on functionals of charge density alone. QMC is stochastic method which explicitly solves the many-body equation. In practice, the DFT method has drawbacks due to the fact that the exchange-correlation functional is not known. A large number of approximate exchange-correlation functionals have been produced to accommodate for this deficiency. Conceptual systematic improvements known as "Jacob's Ladder" of functional approximations have been made to the standard local density approximation (LDA) and generalized gradient approximation (GGA). The traditional functionals have many known failures, such as failing to predict band gaps, silicon defect energies, and silica phase transitions. The newer generation functionals including meta-GGAs and hybrid functionals, such as the screened hybrid, HSE, have been developed to try to improve the flaws of lower-rung functionals. Overall, approximate functionals have generally had much success, but all functionals unpredictably vary in the quality and consistency of their predictions. Often, a failure of one type of DFT functional can be fixed by simply identifying another DFT functional that best describes the system under study. Identifying the best functional for the job is a challenging task, particularly if there is no experimental measurement to ii compare against. Higher accuracy methods, such as QMC, which are vastly more computationally expensive, can be used to benchmark DFT functionals and identify those which work best for a material when experiment is lacking. If no DFT functional can perform adequately, then it is important to show more rigorous methods are capable of handling the task. QMC is high accuracy alternative to DFT, but QMC is too computationally expensive to replace DFT. Hybrid DFT functionals appear to be a good compromise between QMC and standard DFT. Not many large scale computations have been done to test the feasibility or benchmark capability of either QMC or hybrid DFT for complex materials. This thesis presents three applications expanding the scope of QMC and hybrid DFT to large, scale complex materials. QMC computes accurate formation energies for single-, di-, and trisilicon-self-interstitials. QMC combined with phonon energies from DFT provide the most accurate equations of state, phase boundaries, and elastic properties available for silica. The HSE DFT functional is shown to reproduce QMC results for both silicon defects and high pressure silica phases, establishing its benchmark accuracy compared to other functionals. Standard DFT is still the most efficient and useful for general computation. However, this thesis shows that QMC and hybrid DFT calculations can aid and evaluate shortcomings associated the exchange-correlation potential in DFT by offering a route to benchmark and improve reliability of standard, more efficient DFT predictions.


The invention relates to a ship peripheral target detection alarm system. The alarm system comprises a camera component, a sensor component, an image preprocessing device, a target recognition device, a target characteristic extraction device, a target template storage device and a processing device, wherein the camera component, the image preprocessing device, the target recognition device and the target characteristic extraction device are sequentially connected with one another to acquire characteristics of peripheral targets of a ship, the processing device is connected with the target characteristic extraction device and the target template storage device respectively so as to recognize the type of each target, and the processing device also realizes the target detection alarm based on target distances respectively detected by the target characteristic extraction device and the sensor component. By adopting the ship peripheral target detection alarm system, the existence of the peripheral targets of the ship can be conveniently detected in time, the type of the detected target is convenient to recognize, and corresponding alarm information can be provided according to the relative position situation of the target and a ship body.


The elderly subject's decline in all domains lead to a narcissistic libidinal withdrawal centered on instrumental functions, and an impoverishment of intellectual investment (loss of curiosity and creativity, and a tendency to routine). The future becomes a source of anxiety and, in turn, reverie ceases to arouse interest. Investment in memories, especially gratifying ones, takes over in part from the reverie, as memories are the source of multiple and substantial narcissistic satisfactions.


Critical speed is one of several important design criteria for shafts.  Commonly Dunkerley's Equation and/or Rayleigh's Methods are employed to accomplish the calculation.  Both methods rely on a priori determination of shaft deflection at several locations.  For uniform shafts with simple loading the calculations are straight-forward.  For any number of practical reasons, however, shafts are neither uniform nor simply-loaded.  Critical speed determination for these "practical" shafts can become tedious.  Teaching undergraduate students to conduct such calculations is challenging at least. This presentation shows a method for teaching undergraduate students to accomplish the calculations.  We have found that students, overwhelmingly, can learn and use the method with accuracy and understanding.  The method requires that the student can write a moment equation using discontinuity terms, take a partial derivative, and use an equation-solver such as TKSolver TM or EES © .


We consider an epidemic model for the dynamics of an infectious disease that incorporates a nonlinear function h(I), which describes the recovery rate of infectious individuals. We show that in spite of the simple structure of the model, a backward bifurcation may occur if the recovery rate h(I) decreases and the velocity of the recovery rate dh(0)dI is below a threshold value in the beginning of the epidemic. These functions would represent a weak reaction or slow treatment measures because, for instance, of limited allocation of resources o sparsely distributed populations. This includes commonly used functionals, as the monotone saturating Michaelis–Menten, and non monotone recovery rates, used to represent a recovery rate limited by the increasing number of infected individuals. We are especially interested in control policies that can lead to recovery functions that avoid backward bifurcation. Copyright © 2016 John Wiley & Sons, Ltd.


We consider a phase-field model for a phase change process with phase-dependent heat absorption. This model describes the behaviour of films exposed to radiative heating, where the film can change reversibly between amorphous and crystalline states. Existence and uniqueness of solutions as well as stability are established. Moreover, a maximum principle is proved for the phase-field equation.


Over thirty five years have elapsed since the fiber optic gyro was proposed by Vali and Shorthill. In those decades, fiber gyros have matured. They are competing head to head with existing technologies such as mechanical gyros and RLGs in tactical, navigation and strategic applications and are winning. Northrop Grumman has produced the majority of fiber optic gyros and fiber optic gyro based inertial products in the world. This paper will cover the various Northrop fiber gyro products, the platforms they are used on, as well as production and top level system data.


Lecture Board for this issue: Todd M. Bauer, MD; Zineb Belcaid, MD; Ian Chau, MD; Hyun C. Chung, MD; Thorsten O. Götze, MD; Yelena Y. Janjigian MD; Christian Schauer, MD; Lin Shen, MD; S92 Preface S92 Novel approaches in gastric cancer S95 Checkpoint inhibition: predictors, resistance and immunogenomic features S98 PARPand anti-PD-1-based strategies in breast and cervical cancer S102 Anti-PD-1 compounds targeting MSI-H/ dMMR tumors S106 Early insights for CPI combinations in solid tumors S111 Esophageal cancer: taking immunotherapy one step further


Can parents who choose not to vaccinate their children be held legally liable for any harm that results? The state of laboratory and epidemiological understanding of a disease such as measles makes it likely that a persuasive causal link can be established between a decision to not vaccinate, a failure to take appropriate precautions to isolate a non-vaccinated child who may have been exposed to measles from highly vulnerable persons, and a death. This paper argues that, even if a parent chooses to not vaccinate a child under a state law permitting exemptions, that decision does not create complete protection against liability for the adverse consequences of that choice.


With the increasing use of Simulink modeling in embedded system development, there comes a need for effective techniques and tools to support managing these models and their related artifacts. Because maintenance of models makes up such a large portion of the cost and effort of the system as a whole, it is increasingly important to ensure that the process of managing models is as simple, intuitive and efficient as possible. Part of model management comes in the form of impact analysis - the ability to determine the impact of a change to a model on related artifacts such as test cases and other models. This paper presents an approach to impact analysis for Simulink models, and a tool to implement it (SimPact). We validate our tool as an impact predictor against the maintenance history of a large set of industrial models and their tests. The results show a high level of both precision and recall in predicting actual impact of model changes on tests.


As is clear from the historiography of the US decision to use the atomic bomb on Hiroshima, the judgments of historians are relative to the time, place, and perspective from which they are writing. There are four major schools of historical interpretation of the decision. First is the orthodox view that was offered by the participants in the decision. Second is the revisionist view of historians writing during the era of the Vietnam war who adopted a much more critical interpretation. Third is an interpretive school that gives weight to the Japanese role and responsibility. Finally, the author's view is found in a more long-range perspective that finds the momentum created by President Roosevelt's unconditional surrender policy as the decisive factor. This policy provoked unconditional resistance in the Japanese military. By 1945 the legacy of Roosevelt's policy was firmly embedded in American public opinion. Historians have reached no consensus among these different interpretive schools.


15 As illustrated by the approaches presented during the 5 th FSPM workshop (Prusinkiewicz 16 and Hanan 2007, and this issue), the development of functional-structural plant models 17 requires an increasing amount of computer modeling. All these models are developed by 18 different teams in various contexts and with different goals. Efficient and flexible 19 computational frameworks are required to augment the interaction between these models, 20 their reusability, and the possibility to compare them on identical datasets. 21 In this paper, we present an open-source platform, OpenAlea, that provides a user-friendly 22 environment for modelers, and advanced deployment methods. OpenAlea allows researchers 23 2 to build models using a visual programming interface and provides a set of tools and models 24 dedicated to plant modeling. Models and algorithms are embedded in OpenAlea components 25 with well defined input and output interfaces that can be easily interconnected to form more 26 complex models and define more macroscopic components. The system architecture is 27 based on the use of a general purpose, high-level, object-oriented script language, Python, 28 widely used in other scientific areas. We briefly present the rationale that underlies the 29 architectural design of this system and we illustrate the use of the platform to assemble 30 several heterogeneous model components and to rapidly prototype a complex modeling 31 scenario. 32 33 Introduction 34


The article examines the ideological work as a technology for the state policy implementation. The purpose of the study is socio-political audit of modern ideological work. The socio-political audit is sociological analysis of the society's development conditions in order to identify social risks and develop a systematic approach to their solution. Main prerequisites for ideological work and modeling include revival of political competition and multiparty system, pluralism of ideological and political views. The socio-political audit presupposes that there are principles, forms, and methods of ideological activity common to all political parties and public associations significant for each party in particular and the party system as a whole. The solution to the problem of the ideological work lies in the field of modeling and forecasting of socio-political processes and public administration systems. The problems of ideological work receive little attention from state, society, and research community.


By analyzing the color difference of the emulating samples which are made from the program PHOTOSHOP.The reasonable emulating proof draft is preferred under the practical program.At the same time,some optimizing measures are put forward.It is useful to improve the color difference of white point and the whole images on some degree.


PURPOSE: To record required picture information judging from display contents of a display unit, by transmitting a coded-character signal string of a coded title, gist, etc., before a picture signal and by displaying the above-mentioned coded character signal on the display unit at a reception side. CONSTITUTION: By selective button 1, a receiver should set classification codes, for the classification of fields of picture information, to 1st classification-code memory 2. Once a facsimile signal from transmitter 3 is received, a classification code added at the beginning of reception signal 4 is set to the 2nd classification-code memory 5 and compared by coincidence circuit 6 wich the classification code set to memory 2. In case of coincidence, gate circuit 7 is made to open to set the coded- character signal string to memory 8, and it is regenerated in a display character form by character generator 9 and displayed on display unit 10. Judging from the display contents, the receiver depresses recording button 12 for recording. COPYRIGHT: (C)1979,JPO&Japio


The authors investigate the interface in Portland cement matrix by performing x-ray and differential thermal analysis on ten-year-old samples of the boundary layers of glass cement containing untreated fiber glass and fiber glass treated with V-III and KBKV polymers. They conclude that the polymers modify the boundary layers of the cement matrix with the formation of highly crystallized, low basicity hydrosilicates and chemical compounds similar to chelates. The alkali-resistant polymers permit using alkali-free fibers as fiber glass reinforcement.


Objective To investigate the distribution of apolipoprotein (apo)E polymorphism and affection of apoE genotypes on plasma lipids in children with family of coronary heart disease(CHD). Methods apoE genotypes in 83 with and 282 without family of CHD were determined by polymerase chain reaction restricted fragments length polymorphism. Results Compared with control group, the frequency of apoe4 allele was higher in children with family of CHD. It was significantly highest among the children whose parents or grandparents at 45 years of age or younger with CHD, the other children of this group and the children of control group. ApoE polymorphisms may affected plasma lipids metabolism in those healthy children with family of CHD. The levels of total cholesterol (TC), low density lipoprotein cholesterol(LDL C), lipoprotein (a),apoB100, apoE had difference among carrier with apoe2, e3, e4 alleles. The children with apo e4 allele had higher levels of TC, LDL C, apoB100, and lower levels of apoAI?apoE than those with apoe3 alleles. The children with apoe2 allele had lower levels of TC, LDL C and lipoprotein( a). Conclusion There is abnormality of apoE polmorphisms in children with family of CHD, which may affect plasma lipoproteins metabolism.


In this paper we prove the transitivity of the set of all reflections of an orthogonalspace on some sets of lines. Applying this property, we can find all integral solutionsof some quadratic equations with integral coefficients and simplify the proofs of Witt'sTheorem and the Inertia Theorem. Concerning an onthogonal space over a finite field,two expressions relating the number of the square lines and the number of the isotropiclines are obtained, so that the number of isotropic lines, the number of the square linesand the number of the nonsquars lines are calculated. Finally, a result of ShenGuangyu is generalized: for a multivariable quadratic polynomial f with coefficientsin a finite field, the number of arguments that f takes square values and the number ofsquare values that f can take are calculated. Throughout this paper, we assume that the characteristic of the field is differentfrom two.


1P.G Scholar, Department of Civil Engineering, Indian Institute of Technology Delhi, India 2Proffesor, Department of Civil Engineering, Indian Institute of Technology Delhi, India ---------------------------------------------------------------------***---------------------------------------------------------------------Abstract – The importance of quality control of concrete in civil engineering structures, especially in structures which demands a huge and continuous casting of concrete in a short period of time, becomes an essential issue to be emphasized now a days in the construction industry. The conventional retrospective quality control method is to take samples from the mix which is going to be cast in the desired structure and make inferences based on the 28th day compressive strength result. The problem associated with this method is the length of time required before the result are known, leading to be late to take remedial action as the earliest as the concrete is in its green state. To avoid the problem, correlations has been established by different researchers and different codes (such as IS 9013, BS 1881and CAN/CSA-A23.2) to predict the 28th day strength of concrete from early test (usually 1 day) depending on different parameters. However, every correlation is sensitive to changes in mix proportions. This paper investigated the reliabilities of one single correlation when changes made in the mix proportion for the selected W/C ratios of 0.60, 0.50 and 0.35 and the obtained correlation is also compared with that proposed in IS 9013 of warm water curing method. The result showed that single correlation is not a reliable prediction tool when changes made in proportions. Whereas, comparison with IS 9013 is found statistically similar.


Christiaan Huygens (1629-1695) was born the son of diplomat Constantijn Huygens, and grew up in the company of prominent men, such as Rene Descartes. After his studies in mathematics at Leiden University, he developed himself into an important astronomer. His research included the rings of Saturn and the discovery of the moon Titan. Huygens is also known as the inventor of the pendulum clock. The Elzeviers published his first book on hyperbolae, ellipses, and circles in 1651. It was followed by this treatise on the magnitude of circles in 1654.


In the design and operation of industrial processes, physical and thermodynamic property data are required. Increasingly stringent regulations are making water solubility of substances even more critical. Water solubility data of naphthenes, or cycloalkanes, is applicable for the complete range of salt concentrations, including water without salt to water saturated with salt. The results are intended for use in initial engineering and environmental applications. Solubility values from the correlation are useful in determining the distribution of a hydrocarbon spill on its contact with sea water. Solubility values at other salt concentrations also may be computed. Results are presented for water solubility of hydrocarbons (naphthenes) as a function of salt concentration (log(S) = A + BX + CX[sup 2]). The correlation constants, A, B and C, are displayed in an easy-to-use tabular format that is applicable for rapid engineering use with the personal computer or hand-held calculator. The results for solubility in salt water are applicable for the complete range of salt concentrations. This range covers water without salt, X = 0, to water saturated with salt, X = 358,700 ppM(wt). Correlation and experimental results are in favorable agreement.


Abstract: The paper was to investigate the tax assessment system and tax collection of small taxpayers in the case of Gambella Regional state. To achieve the objectives of this research, both a quantitative and qualitative research approach was adopted and a descriptive & explanatory research type was employed. Probability and non-probability technique were used to select samples. Primary and secondary data source were collected with questionnaires, interview, and review documents. The identified key problems were; taxpayers are not registered voluntary, complexity of the tax laws and regulation, inexperienced daily income estimating committees, unable to make regular assessment on daily income, unfair estimation of daily income estimating committee, inappropriate enforcement action and audit, Finally, based on the findings possible recommendations were given. These include, develop awareness' creation, improving service delivery, simplifying the tax rules and regulation, frequently building the capacity of the estimating committee, regular assessment of income, ensuring fairness and equity, improving the performance of collection, strengthen the audit, established independent appeal committee and commission.
Keywords: Estimating committee, daily estimated income, assessment methods.


The driving time and usage of reverse gear are much less than other driving situations, but the dangers are easy to be ignored due to of the blind spots when driving the car in reverse gear. The safety in the rear is always an important issue for vehicles. In this work, a rear obstacle detection technique is proposed to remind the drivers when moving backwards. We use a binocular camera system for rear obstacle detection based on parallax map. An image representation called stixel is adopted for the outdoor traffic scene in a columnar manner. The disparity map is used to estimate the ground region, identify the free space, and segment the obstacles based on the height. Finally, a road edge tracking step is incorporated to to stabilize the system. In the experiments, several reverse parking video sequences are acquired to validate the effectiveness of the proposed algorithm.


It is a matter of great privilege that the School of Studies in Electronics & Photonics, School of Studies in Physics and Astrophysics, and Luminescence Society of India organized 3-days National Conference on Signal Processing, Sustainable Energy Materials and Astronomy and Astrophysics (NSSEMA). On the first day i.e., on the 16th of March 2023, the conference was inaugurated by chief guest Prof. Keshari Lal Verma, Honorable Vice Chancellor of Pt. Ravishankar Shukla University, Raipur, Guest of Honor Prof. S. K. Pandey, Former Vice-Chancellor, Pt. Ravishankar Shukla University, Raipur, Prof. A.G. Ramakrishnan, IISc, Bangalore, and Prof. K.V.R. Murthy, President, Luminescence Society of India. The inaugural session was started with lamp lightning and the welcome speech by Prof. Kavita Thakur, Convener, and Head, S.O.S in Electronics and Photonics, and Prof. Nameeta Brahme, Convener and Head, S.O.S in Physics and Astrophysics. Guest of Honor Prof. K.V.R. Murthy has explored the opportunities in the area of Science and Technology, Luminescence, Physics, Electronics and Photonics are connected and briefly described the activities of LSI. Guest of Honor Prof. A.G. Ramakrishnan told researchers to emphasize their art of learning and gave best wishes to everyone. The informative speech was delivered by our Vice Chancellor, Prof. Keshari Lal Verma followed by the release of souvenirs. A vote of thanks was delivered by Prof N.K. Chakradhari of S.O.S in Physics and Astrophysics. The technical session-1 was started with an invited talk by Prof. K.V.R Murthy, President, of the Luminescence Society of India in which he discussed different types of luminescent materials and their advantages and application in daily life. The second plenary talk was delivered by Prof. K.V.R Chary of Rowan University, he discussed the fundamentals of magnetism and rules for predicting magnetic order in oxides and the safe handling of nanomaterials. After lunch, the technical session-2 was started, Prof. Dipankar Banerjee of ARIES, Nainital, B.N. Jagatap of IIT, Bombay, Prof. P.D. Sahare of Delhi University, Delhi delivered a invited talk. There was also parallel technical session-3 going on, where Prof. A.G. Ramakrishnan of IISc, Bangalore, Prof. G.V.V Sharma of IIT, Hyderabad, Prof. Rekha Garg of Dr. HS Gour University, Sagar, Prof. Narendra D Londhe of NIT, Raipur delivered an invited technical talk on their respective field. 12 orals were presented by delegates from various institutes and colleges of Chhattisgarh and outside the state. A colorful event was organized on the first day evening in the seminar hall of S.O.S in Physics and Astrophysics by students of S.O.S in Electronics and Photonics and S.O.S in Physics and Astrophysics for the refreshment of the delegates. On the second day of the conference i.e., on the 17th of March 2023, 8 invited talks and 10 invited technical talks were delivered by professors from various prestigious institutes and universities. Also parallel session was conducted so participants get benefit from their knowledge. After lunch, 12 orals and 61 posters were presented by delegates from various institutes and colleges of Chhattisgarh and outside the state. On the third day of the conference i.e., on the 18th of March 2023, 7 invited talks and 11 invited technical talks were delivered by professors from various prestigious institutes and universities. 9 orals were presented by delegates from various institutes and colleges of Chhattisgarh and outside the state. After that, a valedictory program was organized. The chief guest Prof. K.V.R. Chary, Guest of Honor Prof. B.S. Panigrahi, and organizers Prof. Kavita Thakur, Prof. Nameeta Brahme, Prof. D.P. Bisen, Prof. N.K. Chakradhari and Prof. Y.K. Mahipal was present. Program has been started with lamp lightning and was followed by honoring the guest with presents as a memory. Briefing of NSSEMA-23 has been done by Prof. N.K. Chakradhari. Prof. K.V.R Chary addressed that the conference was market disciplinary and informative. Prof. B.S. Panigrahi said that the organization was quite good and everybody actively participated. At the end Prof. D.P. Bisen thanked organizing committee, sponsors, professors and delegates from various institutes and colleges, and participants for the successful conduction of NSSEMA-23. Followed by cash prize distribution by LSI to best oral and best poster delegates. We would like to extend our heartfelt gratitude and admiration towards our esteemed colleagues for their exemplary contribution to the successful conduction of NSSEMA-23. Their dedication, organization, and attention to detail were truly commendable, ensuring that every aspect of the event ran seamlessly. From coordinating speakers and panel discussions to managing logistics and promotional activities, their professionalism was evident at every step. Moreover, their ability to foster a collaborative environment among the participants was instrumental in creating an atmosphere of open dialogue and knowledge exchange. Their tireless efforts not only made a lasting impression on me but also garnered immense appreciation from the attendees and key stakeholders. We are privileged to be part of such a talented team that consistently strives for excellence in all endeavors. We would also like to express our deepest appreciation and gratitude to our valued sponsors for their generous support of our conference NSSEMA-23. Your unwavering commitment and dedication towards making this event a resounding success have not gone unnoticed. Through your sponsorship, you have not only contributed financially but have also demonstrated a sincere belief in the importance of knowledge-sharing and professional development within our industry. Your contribution has enabled us to bring together leading experts, influential speakers, and aspiring professionals from around the world to exchange ideas, share insights, and foster meaningful collaborations. It is thanks to the support of sponsors like you that we are able to organize such a high-caliber conference year after year. We extend our sincerest thanks for your continued partnership and look forward to creating impactful experiences together in the future. List of funding agencies, sponsors, National Advisory Committee, National Organizing Committee, Conference Organizing Committee, Local Organizing Committee are available in this Pdf.


In this paper, we proposed an incremental TFP-tree algorithm for mining emerging patterns that can search efficiently within limitation of memory. Especially, the concept of pre-infrequent patterns pruning and use of two different minimum supports, it made the algorithm be possible to mine most emerging patterns and handle the problem of mining from incrementally increased, large size of data sets. We also defined and analyzed the significant difference of safe and non-safe power load lines and identify which line is potentially non-safe by using those emerging patterns.


The importance of ASEAN adheres to the fact that it has strategic and socioeconomic dimension attached to it. In the recent times, the global security prospects brought up new areas to limelight. ASEAN is an emerging community and in the coming years, its importance is going to increase because of the locational factors and the strategic stronghold it has got. The potential areas of resource collaboration and social formulation make ASEAN community one of the interesting area to focus upon. It is also an emerging economic hub, with the increase and investment of FDI and FII in the region; the global order too has expectation from ASEAN.In the areas of infrastructure too ASEAN has taken new initiative as it is the key issue for development and connectivity. The ASEAN members have diverse ethnic groups andlinguistic concerns yet they declare themselves as one community. Here lies the greatness of a community which is important from the broad scenario of the humanitarian and the integral approach it pertains to. In the coming years ASEAN will play the key role in socioeconomy and maritime concerns for the prosperous world order. ------------------------------------------------------------------------------------------------------------------------------------Date of Submission: 05-09-2018 Date of acceptance: 20-09-2018 ------------------------------------------------------------------------------------------------------------------------------------


It highlights the importance of technique work in forestry even in the reform of collective forest property right system.The work flow in the reform of collective forest property right system concerning the material preparation such as skill,tools,drawings and etc,field regionalization,calculation method of the area and accuracy requirement,fillings of all sorts of diagram,mapping and technique essentials of quality inspection are all elaborated in detail.


A kind of modified tourmaline powder was prepared by using polycarboxylic salts as surface modifiers,and agate beads as abrading media through abrading modified tourmaline powder process.Furthermore,the abrading process was optimized,and the particle size distribution of modified tourmaline powders was tested.The IR spectra provided evidence that the modified tourmaline powders were confirmed with polycarboxylic group,which would further enhance their compatibility with various materials.The amount of released negative ions from modified tourmaline powders was about 600/cm3.


In this paper the optimal policy and the stability of a tariff agreement among the importers of a monopolized good that is sold in an integrated market are studied. To analyze the stability, the tariff agreement formation is modelled as a two-stage game. In the first stage each importer decides whether or not to sign the agreement and in the second stage the signatories and non-signatories choose their tariff whereas the monopoly chooses the quantity or the price. The findings show that the optimal policy of the importers depends on which strategic variable is selected by the monopolist but that, on the contrary, this decision has no effects on the level of cooperation that can be reached by a self-enforcing tariff agreement that, in any case, is very low.


Cycocel applied as a 5000 ppm soil drench 31 days after sowing reduced height 8 to 10 cm and caused 8 to 16 days earlier flowering of F1 geranium 'Carefree Scarlet' when compared with plants which had not been treated with Cycocel. Manually irrigated plants were shorter, flowered earlier, and were more compact, as measured by fresh weight, than automatically irrigated plants for this Cycocel treatment. Pinched plants were short and well branched but so much delayed in flowering that this method of height reduction would not be acceptable for commercial use.


This study examines the use of Moodle assisted online collaboration environment in a Special Teaching Techniques class. In this paper, the authors investigate the effect of Moodle assisted online collaboration on prospective secondary mathematics teachers' attitudes toward the use of the Internet and evaluate the prospective teachers' opinions regarding the process. The method of this study is one grouped pre-test post-test model. The 30 participants of secondary mathematics education without thesis program are the study group of this research. The special mathematics teaching techniques class supported lessons with the help of the Moodle environment for 9 weeks. After the process, no significant difference existed in the attitudes of the prospective mathematics teachers toward Internet usage. However, according to the interviews, the teachers said they found the process advantageous and favorable and want further implementations in other classes.


A characteristic trend in solid state physics is the roughly exponential de crease with time in available tempera ture and the size of devices — see Figs. 1 and 2: during the last two decades, temperatures have dropped by four orders of magnitude and the size of com mercial devices by two orders of magni tude! Of course in Fig. 1, record tempe ratures are presented, but 50-100 mK is not out of the way in the laboratory. The development of micron and submicron devices, in part related to advances in computer technology, has resulted in in sulating thicknesses becoming as small as 100 A. This trend to subkelvin tempe ratures and to micron and submicron devices leads to qualitatively new physi cal properties. At temperatures where thermal fluc tuations may be neglected, the Schrödinger equation is applicable to the whole macroscopic system. It predicts the eigenstates, which depend on the microscopic structure of the system and are therefore individual for each given system. In this respect, a macroscopic system resembles a giant "superatom" with a specific energy spectrum. Its spectroscopy should also be as specific as the familiar spectroscopy of atoms and molecules. Thus, at a sufficiently low tempera ture T, any system becomes a macro scopic quantum system. The higher the temperature, the smaller the system must be. In micron and submicron MOSFETs, the Si inversion layers may fall into the range in question. The behaviour of such systems is very unusual, as de monstrated in e.g. experiments by Fowler, Hartstein and Webb (see Fig. 3). The plot can be viewed as representing the conductance G of a sample (10 μm long, 100-300 A wide and 50-80 A thick) against the number N of electrons in the sample. The electron density n in the experiment is controlled by the ap plied gate voltage V and N varies from  104 to 1.5 x 104. The corresponding Fermi energy changes from  20 meVto  30 meV. Clearly G(N) exhibits uncon ventional features : (i) The envelope dependence of the con ductance on the electron density is ex ponential rather than linear. (ii) The addition of only a few extra elec trons may change the conductance by two orders of magnitude. (iii) The peaks in G are extraordinarily sharp and narrow. (iv) The overall structure of G appears chaotic. Indeed, the peaks seem ran domly situated, whereas they are uni que to any given sample, and are per fectly reproducible even after moderate temperature cycling. (v) The temperature dependence of maximum (peak) and minimum (valley) conductances G follow the variable range hopping law predicted by Mott: In G ~ -<T0*/T)1/2 (1) as shown in Fig. 4. The reference temperature TO* rela ting to peaks is itself a chaotic function of the electron density superimposed on an overall exponential envelope that is dependent on n. For instance, the high est peaks, observed by A. Hartstein et al. have values of TO* shown in Table 1. Such "reproducible chaos" is a cha racteristic feature of a number of small systems at low-temperature. To under stand these results, first consider quan tum scattering by two one-dimensional barriers (we choose rectangular for sim plicity) with a potential well in between (Fig. 5). Suppose the transmission coef ficients of the barriers are t1 and t2 < t1 << 1. At most energies, the total trans mission coefficient t12 is given by:


Improving control standards of point(PSP) and non-point(NSP) source pollutions are recent highlights of water and environmental issues.Agricultural non-point source pollution(AGNSP) problems caused especially by heavy use of chemical fertil-izers and pesticides are prominent in this regard.Quantitative research on pollution loads is the basis of control standard,evaluation and management of AGNSP.Using AGNSP and unit-load characteristics,an AGNSP model was developed that uses source/sinks modules determine the complex migration routes of pollutants.The source module was further divided into farmland irrigation drainage and farmland contaminant concentration estimation sub-modules.The sink module was also divided into farmland drainage and pollutant migration/transformation sub-modules.By integrating the modules,a complete AGNSP load model was therefore es-tablished.The integrated AGNSP model was tested in the Qingtongxia Irrigation District(QID) in upstream reaches of the Yellow River.The 2008 crop pattern was used in the developed AGNSP model to simulate AGNSP load and output in QID.Based on the simulation results,salinity,total phosphorus,total nitrogen,nitrate nitrogen and ammonia nitrogen in QID were 470 099 t,98.17 t,3 593 t,2 122 t and 426 t,respectively.The application of the established AGNSP model indicated that the model presented prefer-able simulated results,and was practicable in the similar studies.


The development of methods for the processing of images and signals is one of the oldest research topics in medical informatics. Already early after the introduction of computers, methods were either developed for the analysis of, for example, signals generated by laboratory equipment, and of ECGs and EEGs, adopted from other disciplines. In parallel, image processing methods were developed, e.g., for analyzing cells, chromosomes and images from cytology, radiology and nuclear medicine. The goals of signal and image analysis varied, but classification of signal and image components was an impor-. tant topic. Both methods that were developed with specific applications in mind and generic methods have to be validated and evaluated. Algorithms usually compute a number of parameter values that are to be determined from available signals. When the algorithm is very elaborate, the number of parameters may become so large that the determination of their optimal values becomes impractical; the time to perform the analysis with sets of values for each of the various parameters becomes too long. Therefore, many complex algorithms usuallyuseanumber of parameters (thresholds) whose values have been determined by trial and error. It was realized early on that, in order to evaluate the performance of the algorithms, data sets should be used other than those used for training the algorithms. Therefore, a distinction


By the method of documentation,questionnaire investigation and mathematical statistics,it analyzes seven handball traditional sports project school in Anhui province based on the cultivation of the student athletes present situation. Also it surveys the age of the athletes,athletes training and competition situation,the participation motive,athletes academic situation,and the current situation of parents' attitude of students. The results show that the main problems exist in the current handball traditional sports project school student athletes in Anhui province are: short training period,competition is less and contradictions between learning and other issues. It puts forward the corresponding countemeasures and suggestions in accordance with the actual development.


A white beam collimator has been built to increase the efficiency of a diamond high-heat-load premonochromator. The collimator is composed of a water-cooled beryllium compound refractive lens. We demonstrate a 30% increase in spectral flux of the diamond premonochromator (at 22.6 keV) by using the collimator.


In a recent communication, Bowen (1953) notes the tendency for heavy falls of rain at stations widely scattered over the southern hemisphere to occur on certain dates rather than on others. Surprisingly enough, records for the British Isles show maxima of frequency of heavy rain on the dates, or close to the dates, of peaks for the southern hemisphere stations concerned.


In order to improve the accuracy of pronunciation and evaluation of Chinese Putonghua, it is necessary to deal with the multi-module feature fusion of Putonghua. A comparative method of pattern recognition is proposed based on genetic algorithm (GA) and high order spectrum feature fusion of Putonghua pronunciation in Chinese Putonghua pronunciation standardization. The acquisition model of Chinese Putonghua speech pronunciation signal is constructed, and the filter processing and adaptive feature matching of the collected Mandarin speech signal are carried out to extract the statistical feature quantity of Putonghua speech signal. The method of spectral feature analysis was used to fuse the pronunciation features of Putonghua, and the correlation was detected according to the action attributes of phonetic organs. The high order spectrum characteristics of Chinese Putonghua speech pronunciation signal are extracted, and the modeling and adaptive learning of Chinese Putonghua speech pronunciation feature are carried out by means of statistical average detection and genetic evolutionary algorithm, and the adaptive optimization is carried out according to the genetic evolution process. The multi-module feature fusion of Putonghua is realized, which provides a standardized contrast mode for pronunciation. The simulation results show that the method has high accuracy in speech pronunciation feature detection and pattern recognition, improves the ability of multi-module feature fusion of Putonghua, and is effective and reliable for acoustic modeling of Putonghua pronunciation features. It has good application value in guiding the study and training of Putonghua.


and marginal farmers in the countryside tend to shy away froni a system which requires thcm to run to different agencies and organisations for obtaining their various requirements. Thus the problems and prospects of rural development, with special referencc to the devclopment of the rural poor in India, have been intensively discussed in the book. Its concern for the upliftment of the rural poor through agrarian reforms, unionisation and technological and institutional changes deserves appreciation. Nevertheless, there are certain important omissions and commissions. First, an unduly great significance has been attached to the role of the government in bringing about agrarian reform and institutional changes in favour of thc poor. This betrays a sensc of bourgeois class character of thc ruling government. The book does not answer the question why the state which is represented mainly by thc relatively richer section of the rural population should help promote organisations of the rural poor. Secondly, the suggcsstions that a proportion of all resources and services provided by the public delivery system should be reserved for the poor and that the pricing system should be used to assist the poor, do not carry much weight in view of the failure of some of the special development programmes earmarked for the rural poor in the past. In fact, poverty is the greatest cause of poverty and as long as the income gap between the rich and the poor remains significant, there would be leakages in any system of reservation for the poor and any resources meant for thc poor might really be grabbed by the rich through manipulations. On thc whole, however, the book makes interesting reading, stimulating creattive ideas in the minds of its readers and may be useful for all those concerned with rural development administration in India.


In this paper, we study iterative algorithms for finding approximate solutions of completely generalized strongly nonlinear quasivariational inequalities which include. as a special case, some known results in this field. Our results are the extension and improvements of the results of Siddiqi and Ansari, Ding, and Zeng.


In more than one spatial dimension, resonant linear conversion from one wave type to another can have a more complex geometry than the familiar 'avoided crossing' of one‐dimensional problems. In previous work we have shown that helical ray shapes are generic in a mathematical sense. Here we briefly describe how the local field structure can be computed.


In general, printed documents may contain several different languages. Therefore, to use Optical Character Recognition (OCR) for multi-lingual documents, it is necessary to automatically separate these languages. In this paper, we describe a method for identification of printed Farsi and English text from images of documents in line and word levels. The proposed algorithm is developed based on statistical and shape-based features. The accuracy of this method is around 96.05%.


Shortening and misalignment can be complications of corrective techniques used for hallux valgus when overaggressive bone resection is performed, thus resulting in a toe that lacks stability and function. This can cause functional and cosmetic concerns for the patient. We present a case of a patient with first shortened proximal phalanx and persistent extension of the first metatarsophalangeal joint corrected by gradual bone digital lengthening with external fixation. This lengthening procedure was safe and stable, and restored length and function of the toe.


As society faces concerns over rising obesity rates, traffic congestion and global warming, attention is turning to the importance of creating more walkable environments. The objective of this study was to investigate how community stakeholders, at both neighbourhood and municipal levels, describe the socio‐political process of creating walkable neighbourhoods. Thirty‐one key informants were interviewed about walking issues identified by older people in four different neighbourhoods in Ottawa, Canada. Five dimensions of the process were identified through qualitative analysis that elucidated insights on political context, access channels, resources, actors and opportunities. Creating walkable neighbourhoods is ultimately a political process that involves the convergence of resources facilitated by actors who are able to bridge sectors, organizations and levels of the system. Mobilization of resources at the neighbourhood level affected citizens' abilities to utilize access channels and act on opportunity raising considerations around equity. Future efforts to improve walkability will require that conventional bureaucracies develop approaches that are sensitive to place‐based needs.


OBJECTIVE
In Japan, the number of elderly patients on hemodialysis has markedly increased in recent years. We conducted a survey to confirm the current status of inpatient hemodialysis patients and dialysis facilities with the aim of providing better care.

MATERIAL AND METHODS
The subjects were 57 dialysis patients admitted to the Jishu Hospital for three consecutive months or longer as of February 2004. The survey was conducted by obtaining informed-consent from the patients and their families. The patients were interviewed and a questionnaire was sent to their families. The survey items were as follows; 1) patient characteristics, 2) domestic status, 3) physical and mental condition and 4) awareness concerning the hospital.

RESULTS
The survey showed that dementia is present in almost all elderly hemodialysis patients and they require some degree of assistance for the activities of daily living. In addition, 57.9% patients had already been admitted to or had visited two or more hospitals. The current status of inpatients had improved slightly. Although the period of hospitalization was longer than one year in 64.9% of respondents, it had decreased by around 13% in comparison with that in the previous survey at 1997. These results were considered to be caused by increases in inpatient dialysis facilities, aging-related deaths, and by patients switching to home care after discharge because of the higher economic burden. In the interview, some patients were satisfied with inpatient life, but about one half of the patients said they wanted home care. Key caregivers for patients are mainly middle-aged or older family members (> 50 years old), indicating that caregivers are aging. On the other hand, the present study showed that hospitalization provides advantages for family life, such as improvements in peace of mind, life rhythm, leisure time and physical condition.

CONCLUSION
Since the aging of dialysis patients results in a decrease in physical activity and progression of dementia, long-term hospitalization has a high potential to induce bedridden patients. In addition to the requirement for more long-term facilities, efforts should be made to improve physical activities and inhibit the progression of dementia.


Agriculture is the key to rural development, while agricultural machinery automation controls the development of agriculture and the direction of development. In this paper, the status of development of agricultural machinery automation in China is briefly introduced. Although the level of agricultural machinery automation in China has been greatly improved in recent years, there are still many unsatisfactory points. This paper analyzes and discusses the current situation of the development of agricultural machinery automation in our country. At the same time, it analyzes the existing problems and finally puts forward how to promote the automation of agricultural machinery.


The utility model relates to coal mining and conveying machinery, in particular to a locking device of a crusher hammer, which comprises a base plate and a locking cushion, a through hole is formed besides the central hole of the base plate, one segment edge of the locking cushion is folded to form a bend plate, the locking device is arranged at one side of the base plate, the bend plate of the locking cushion is inserted in the though hole of the base plate, and the base plate and the locking cushion are fixed through the through hole on the base plate and the bend plate of the locking cushion. The utility model solves the problems that the crusher causes bolts to loosen and the hammer to drop due to the cyclic loading impact effect during the working process, and can improve the working efficiency and safety of the whole crusher.


We applied depth-resolved second-harmonic-generation imaging of dermal collagen fiber for estimating burn in fresh chicken skin. Depth and area of the burn was visualized by difference of image contrast between burned and sound area.


CONTEXT/OBJECTIVE
Our objective was to describe early participation in Whole Health programs across the Veterans Health Administration (VHA) Spinal Cord Injuries and Disorders (SCI/D) System of Care.

DESIGN
Retrospective analysis of VHA administrative data.

SETTING
The VHA SCI/D System of Care.

PARTICIPANTS
Veterans with SCI/D included in the FY2019 cumulative VHA SCI/D Registry cohort with living status during FY2017, FY2018, and FY2019.

INTERVENTIONS
N/A.

OUTCOME MEASURES
We assessed the number of encounters and unique Veterans with SCI/D, and the percent of Veterans with SCI/D, who utilized each Whole Health (WH) program available in VA.

RESULTS
Utilization of WH Pathway and well-being Programs increased from 62 encounters to 1703 encounters between FY2017 and FY2019 (representing 0.09% to 3.13% of Veterans with SCI/D). Utilization of chiropractic care rose from 130 encounters to 418 encounters during the same time period. Similarly, utilization of complementary and integrative health programs increased from 886 encounters to 2655 encounters (representing 1.09% to 3.11% of Veterans; FY2017 to 2019). We also report utilization of specific WH programs.

CONCLUSION
Participation in WH services has been increasing among Veterans with SCI/D who receive health care from the VHA SCI/D System of Care. However, utilization among Veterans with SCI/D remains low overall, and targeted efforts to increase WH program reach are needed. Additional information about the relative effectiveness of different strategies to support WH implementation is also needed, to ensure strategies likely to have the most impact are prioritized.


http://www.ecmwf.int/en/computing/access-computing-facilities/forms Jun 2021 Page 1 of 11 1 The Principal Investigator will act as contact person for this Special Project and, in particular, will be asked to register the project, provide annual progress reports of the project's activities, etc. 2 These figures refer to data archived in ECFS and MARS. If e.g. you archive x GB in year one and y GB in year two and don't delete anything you need to request x + y GB for the second project year etc. REQUEST FOR A SPECIAL PROJECT 2022–2024 MEMBER STATE: ITALY Principal Investigator1: ANDREA STORTO Affiliation: CNR-ISMAR (Institute of Marine Sciences, National Research Council) Address: Via del Fosso del Cavaliere 100, I-00044 Rome, Italy Other researchers: Chunxue Yang Eva Le Merle Jacopo Busatto .................................................................................. Project Title: Enhancing regional ocean data assimilation in high and mid latitude European seas


practicable thing to offer them such a new world partnership that they will only be too eager and glad to come in. There is an old fable which is always new, the story of the traveler and his cloak and the sun and the wind. The wind laughed and said, &dquo;See me take that man's cloak off,&dquo; and he blew hard and whistled sharply, and the man wrapped his cloak about him as closely as he could. The sun smiled and said, &dquo;See me do it,&dquo; and before he had done smiling the man had the cloak over his arm. The nations desire nothing better than to throw away their armies and get rid of them. They are the most burdensome cloak


Introduction and objective The purpose of this systematic review is the identification of work-related risk factors for the occurrence of back disorders. Several reviews on this topic have been published so far. However, none of these included clearly stated in- and exclusion criteria as well as a methodological quality assessment of the studies. Material and method The available literature was selected in an automatic search of the data bases Medline, Embase, Psyclit, NIOSHTIC, CISDOC, HSELINE and Sportdiscus. The abstracts of all the citations were retrieved and examined. Studies had to meet the following criteria to be included in this review: 1) The design was case-control, prospective or retrospective cohort; 2) The population was a working or a community-based population; 3) The outcome measure was based on symptoms or signs of non-specific low back pain or sciatica. The selected publications are independently scored by two reviewers according to a set of methodological criteria regarding informativeness, validity and precision. The criteria concern the purpose and population of the study, exposure and outcome measurements, analysis and data presentation. Two different criteria lists are used for case-control and cohort studies. These lists were adapted from criteria lists used in systematic reviews of RCT's on treatment. The reviewers rate each methodological criterion positive, negative or unknown based on the information presented. Each study is assigned a total methods score by summing up all the positive validity criteria. The relationship between a potential risk factor and the outcome is considered positive in case of a statistically significant association, negative in case of no association and inconclusive in case of no association, but insufficient power of the study at issue. Furthermore, the magnitude of the odds ratio's and relative risks found, are compared and summarized, taking into consideration the methodological quality of the available studies. Results The literature search based on information provided in the different data bases resulted in the identification of 173 publications, mostly in English. However, this selection includes references with too little information to make a final decision about in- or exclusion. The next step will be a further selection based on the information in the full papers. At the conference the final results will be presented, including the methodological quality assessment and the overview of the strength of the evidence for each risk factor identified.


Individual oral hygiene, professional dental care and subjective satisfaction with the oral health were investigated in 600 persons representative for the German- and French-speaking population of Switzerland. They cleaned their teeth on average 2.4 x per day, 85% had a "family dentist" whom they had last visited 14.6 months ago and who works to their full satisfaction. On average, every 13.5 month they underwent professional cleaning of their teeth which was performed in 55% by their dentist and in 45% by a dental hygienist. They were well satisfied with the condition of their teeth and gums and even better so with their reconstructions. In 1984 a gap of consumption of toothbrushes and toothpastes had been apparent in over 50-year-old people. Today this is just visible in the over 60 year old. 40 to 60 year old people care for their oral hygiene and regularly go to professional control and cleaning appointments. Only over 60 year old people are consuming slightly less dental services and buying less toothbrushes and toothpastes. Turning points are loss of teeth, retirement, isolation and sharp cuts in income.


Sixty-three agricultural cooperatives had direct exports of $3.2 billion in calendar year 1980. Grains and preparations had the largest dollar volume of direct exports, followed by oilseeds, cotton, and fruits. Cooperative share of U.S. agricultural exports decreased from 9.2 percent in 1976 to 7.8 percent in 1980. Asian and European countries were the largest markets for direct exports by cooperatives in 1980.


One adult male cycled 20 km at a rate of 50 rpm every 2-3 days for a period of 658 days on an ergometer. The load was 600 kpm/min (days 0-210) and then increased to 900 (days 211-322). Deep Temperature (DT) measurements were taken between days 323639 at three sites (1=900) and at one site (1=300 or 900) using a non-invasive DT instrument. Blood Pressure (BP) and Heart Rate (HR) were non-invasively measured. A load-dependent increase in BP, HR,and thigh DT occurred at loads of 300 and 900. (BP:10+0.9 vs 17k1.3 mmHg); (HR:19fl.l VS 53f1.5 bts/min); and (DT:1.38+0.07 vs 2.17 _+O.O8OC). (n=30, pe 0.05) A site-dependent significant increase in DT occurred during each 20 km trip from three body regions (Umbilical:0.57fO.O5OC) (Sternal:1.22k0.07°C); (Thigh:2.17k0.08°C)


Objective To investigate the effect of infusing umbilical cord blood in treating patient with chronic severe hepatitis B. Methods Sixty subjects were randomly divided into two groups.Half of them were assigned to control group, and the other to experiment group. All patients were accepted an ordinary synthetic trea tment. Xenogenous typespecific umbilical cord blood was only infused to the subjects in experimental group. The levels of serum TBIL, ALT, CHE, PTA and blood routine in all subjects before and after treatment were measured respectively. Severe hepatitis complications and curative effect were also analyzed. Results ①The level of TBIL after treating with umbilical cord blood were lower than that of the control group, P0.05,and the levels of CHE and PTA after treating with umbilical cord b lood were much mor e improved than those of the control group, P0.05.②The levels of red blood cell and Hb after treating with umbilical cord blood were not significantly more decreased than those of the control group, P0.05.③Severe hepatitis complications and curative eff ect were also much more improved than that of the control group, P0.05. Conclusion Treating with umbilical cord blood can improve the liver function, decrease severe complicatio ns and increase the rate of improvement in the patients with the chronic severe hepatit is B. So treating with umbilical cord blood may be an important supplementary therapeu tic measure for severe hepatitis.


The aim of the present research is to provide a conceptual framework that connects store atmospherics and salespeople's attributes and behaviours and assess their relevance in shaping a customer's overall experience in a luxury store. Our findings prove empirically that salespeople's attributes and behaviours are more important than store atmospherics in determining customer satisfaction, even if the latter exerts a partial moderation effect on the perception of the former. The empirical results also suggest that giving advice to the customer and closing the sale are the most influential aspects of the development of an effective customer-centric experience and that demonstrating empathy and care skills are therefore particularly crucial in the selection and training of salespeople. The managerial implications are discussed.


ABSTRACT The fully developed forced convective heat transfer flow in a curved square duct is studied, under a constant uniform wall temperature axially and peripherally. The continuity and momentum equations are solved with a new numerical-variational method denoted the CVP method. The method uses a nonstaggered grid for all primitive variables without introducing spurious oscillations in the solutions. Numerical results are presented for the effects of the curvature, the Dean number and the stream pressure gradient, on the velocity, the temperature, the friction factor, and the Nusselt number for fluids with Prandtl numbers 0.7 and 7. The accuracy of the method is discussed, and the results are in close agreement with those obtained by other methods.


Objectives To estimate HIV prevalence, the number of people living with HIV/AIDS (PLWHA) and the undiagnosed proportion in the Netherlands for 2012, and to compare these with published 2007 estimates. Design Synthesis of all available data sources. Methods Multi-Parameter Evidence Synthesis (MPES) was used to obtain estimates in mutually exclusive key populations at higher risk in three geographical regions (Amsterdam, Rotterdam, rest of the Netherlands). Data sources included HIV prevalence surveys, diagnoses at STI clinics, and registered cases in HIV care. Group specific estimates were reported as Bayesian posterior medians and 95% credible intervals (CrI). Results The 2012 model estimated 24,350 PLWHA (95% CrI 20,420–31,280) aged 15–70 years; 2,906 (+14%) more than in 2007. The estimated population HIV prevalence was 0.20% (95% CrI 0.17–0.26%). The overall proportion of undiagnosed HIV was lower in 2012 (34%, 95% CrI 22–49%) compared to 2007 (40%, 95% CrI 25–55%). After MSM, migrants from sub-Saharan Africa and the Caribbean formed the largest groups of PLWHA, but proportions of undiagnosed HIV remained high in these groups, 48% and 44% respectively. Amsterdam had lowest proportions undiagnosed for most key populations at higher risk, including MSM and migrants. Conclusions In 2012, the number of PLWHA was higher compared to 2007, while the proportion of undiagnosed HIV was lower, especially among MSM. Higher HIV testing rates, earlier treatment, and an improved life expectancy may explain these differences. HIV interventions need to be expanded in all key populations at higher risk, with special focus on migrants and key populationsliving outside of Amsterdam.


The celestial sky brightness temperature reflected by the ocean surface toward an L-band radiometer induces a signal that needs to be known in order to retrieve sea surface salinity. To provide an accurate correction, the effects of the surface roughness and the antenna gain pattern need to be included. We assess the impact of these effects on the reflected sky signal using the Aquarius radiometer as an example.