The quality of service for latency dependent content, such as video streaming, largely depends on the distance and available bandwidth between the consumer and the content. Poor provision of these qualities results in reduced user experience and increased overhead. To alleviate this, many systems operate caching and replication, utilising dedicated resources to move the content closer to the consumer. Latency-dependent content creates particular issues for community networks, which often display the property of strong internal connectivity yet poor external connectivity. However, unlike traditional networks, communities often cannot deploy dedicated infrastructure for both monetary and practical reasons. To address these issues, this paper proposes Corelli, a peer-to-peer replication infrastructure designed for use in community networks. In Corelli, high capacity peers in communities autonomously build a distributed cache to dynamically pre-fetch content early on in its popularity lifecycle. By exploiting the natural proximity of peers in the community, users can gain extremely low latency access to content whilst reducing egress utilisation. Through simulation, it is shown that Corelli considerably increases accessibility and improves performance for latency dependent content. Further, Corelli is shown to offer adaptive and resilient mechanisms that ensure that it can respond to variations in churn, demand and popularity.


The invention relates to a composite membrane for the selective gas separation, comprising, arranged a layer system with a continuously porous, mechanically strong, backing layer which has an average pore size in the micrometer range with at least one on the support layer, through intermediate porous layer has an average pore size in the range has between 2 and 200 nm, and arranged with a on the intermediate layer, gas-tight functional layer of a mixed conducting material having a maximum thickness of 1 micron. The support layer consists of a structural ceramic, a metal or a cermet, and has a layer thickness of at most 1 mm. The intermediate layer is present in a total layer thickness of a maximum of 100 microns and has an average pore size in the range between 10 and 100 nm. The functional layer comprises a perovskite, a fluorite or a material having a K The layer thickness of the functional layer is at most 50 nm, in particular between 25 and 400 nm. For the preparation of this composite membrane is applied to a continuously porous, mechanically stable carrier layer having an average pore size in the micron range, at least one porous intermediate layer, wherein the intermediate layer has an average pore size in the range between 2 and 200 nm. In this intermediate layer ...


The present work was conducted to study the histopathological changes in the intestine of Capra hircus, naturally infected with the Anoplocephalidean cestode, Stilesia (Railliet, 1892). It has been seen that the cestode Stilesia jadhavae . are not successful in adhering firmly to the intestinal tissue suffering that the worm is not having very close contact but they has developed very weak contact and attached loosly to crypts of Liberkhun. Not much effort is put by the parasite to survive in the intestine and the scolex is not so much helpful. It seems that the environment of the intestine is quite favourable for the worm Stilesia jadhavae which is rich in protein, glucose and fat content. So the worm finds it easy to absorb the same through tegument for grouth and nourishment.


In this paper we describe a series of new thieno and pyrazolo[2,1]benzothiazepine derivatives 7a-o which were synthesized by two different methods both starting from the previously described tricyclic alcohols 1–3. Several components of this series were effective p. o. (per os, orally) in different pharmacological tests currently employed in the evaluation of antidepressant activity.


Thalfoetines A–D (1–4), unique hybrid aporphine alkaloids with a C-7 aromatic unit formed by a new C–C bond linking two building blocks, were isolated from Thalictrum foetidum.


equitable distribution of public school funding remains an important policy issue. Since the late 1960s, a majority of states have faced at least one legal challenge to the constitutionality of their financing systems. These attempts to change funding patterns continue, with new lawsuits filed in 20 states in recent years. Despite this activity, there is some evidence that equity gains made in earlier decades were short-lived.1 This interest in fiscal equity has not been limited to the states. As early as the 1960s, Congress voiced concern over the inappropriate use by states of federal funds intended to improve equity on behalf of disadvantaged children.2 More recently, Congress considered a proposal by the Commission on Chapter I3 to require within-state fiscal equity as a condition for receiving federal funds, and in the summer of 1993 the United States Senate


Provided is a terminal, a processing apparatus, a processing system, and a processing method. The terminal includes a connection unit, an acquisition unit, a memory, a detector, and a transmitting unit. The connection unit connects the terminal to a processing apparatus through a first communication channel for wireless communication using connection information. The acquisition unit acquires identification information of the processing apparatus. The memory stores the connection information for the first communication channel and the identification information such that the connection information is associated with the identification information. The detector detects that the connection to the processing apparatus through the first communication channel is cut off. The transmitting unit transmits, in a case where the detector detects that the connection to the processing apparatus is cut off, connection information used when the processing apparatus is connected to the terminal to the processing apparatus via a second communication channel using the connection information and the identification information stored in the memory.


The European Year of Cultural Heritage has activated a reflection on the European dimension of Cultural Heritage recognizing the value of this fundamental resource for sustainable development. The activities of the Year aimed  at enhancing the richness  and the diversity of Europe 's Cultural Heritage and  at strengthen ing the  sense of belonging to a common European  space. They also offered the oppo rtunity  to  reflect on how to better protect and promote this fundamental resource for Europe,  build ing our common future through a shared understanding of the past.


Labour quality is the foundation and premise of our c ountry's economic development; but the current situation is not optimistic. So i t is urgent to explore the countermeasures for developing and improving our coun try's labour quality to adjust to economic development of our country.


Infection of two English sole, Parophrys vetulus, probably by Glugea hertwigi, is described. Numerous Glugea cysts (xenomas), measuring 0.5–1.0 mm in diameter, were located throughout the entire intestine distal to the stomach and including the pyloric caecae. A few cysts were located in the mesentery, pancreas, and liver. Microscopically, the cysts were composed of a hyaline connective tissue capsule, enclosing an intermediate layer of syncytium and a central mass of mature spores.


The Multimedia Super Corridor (MSC) is an urban mega-project extending south from Kuala Lumpur, Malaysia's national capital, and is modelled on Silicon Valley. From one point of view, it is yet another in a long line of 'technopole' projects and the checkered history of this kind of regional development scheme. However, in addition to familiar themes of economic development, the Malaysian government—especially former Prime Minister Mahathir—has explicitly embedded the project in a variety of national development and national identity goals. In postcolonial Malaysia, MSC is interwoven with complex geohistories of identity and difference such as 'race' and 'class'. Bunnell's text takes readers along a real and imagined transect of MSC from Kuala Lumpur to the new MSC cities of Putrajaya and Cyberjaya, then on to the Kuala Lumpur International Airport. Along this transect, readers navigate the decidedly complex 'siliconisation' of Malaysia and the entanglements of 'development' and 'modernity' in a postcolonial nation. The book is at its best when it documents the active role of urban spaceas-landscape in the creation of citizensubjects deemed desirable for the intended MSC developments. Bunnell convincingly shows how the planning and building of high-prestige sites like Kuala Lumpur City Centre (KLCC) are bound up in explicit attempts by the state to create a new class of urban(e) citizen-subjects for MSC and its national development goals. He critically analyses contests over the representation, use and inhabitation of various landscapes appropriated by the state for MSC. One important consequence of this kind of development practice that Bunnell draws attention to is the proletarianization of already marginalized populations. The central argument of the book contends—and amply demonstrates—that understanding MSC as a symptom of some 'new techno-economic era' (p. 3) or the imagined inexorable 'expansion of a modern "West" into a "non-Western" periphery' is inadequate. Instead, Bunnell argues that MSC should be understood in at least two ways simultaneously: on the one hand, it is an outcome of contingent cultural and political-economic connections that crisscross scales (e.g. 'global''local') and fold together here and there in such a way that a search for fixed 'origins' is misguided. On the other hand, MSC is also constitutive of new attempts to govern 'the suitably high-tech subject-citizens' (p. 7) deemed desirable for MSC and a wider project of nation building in the 'Information Age'. The book is divided into two parts. Part I, covering two chapters, focuses on a theoretical reworking of 'modernity' and introduces the intertwining cultural and political-economic themes making up postcolonial Malaysia. In these two chapters, Bunnell does more than simply lay out a 'context' within which MSC is Social & Cultural Geography, Vol. 6, No. 5, October 2005


In Taiwan, the willingness of the leisure tourism has greatly grown year by year, since the implementation of the two-day weekend calendar. The past condition of considering the accommodation primarily in the hotel has changed, and customer gradually select the home-stay which is more characteristic. The service competition of the hotel system and the home-stay system is progressing, since the "Regulations for the Management of Home Stay Facilities" was promulgated in 2001. The home-stay industry is now under the pressure of limited customer and the high rate of room vacancies. Therefore, it is the essential condition for forever management of the home-stay industry to constructing an effective marketing mix, maintaining customer relationship and promoting customer behavior intention. The visitors of Yong-Mao Forest Villa for example, this study aims to understand the visitor perception and satisfaction degree by the four attributes of marketing mix, recreational satisfaction, customer relationship, and behavior intention. In addition, this study uses visitor's characteristics and consumer behavior as popular variables. The study has the following findings: (1) customer's characteristics is relatively low distinguishable in sex and family's average income; (2) marketing mix, recreational satisfaction, customer relationship, and behavior intention are relatively high distinguishable in job types, and there is a direct or indirect influence relations between the four attributes. These results can offer the operation policy for the home-stay industry, and the reference basis for promoting home-stay customer in marketing mix.


A system which includes a wide-band scanning monochromator has been developed for the monitoring of the deposition of optical thin film coatings. This instrument measures the transmittance of the growing films over the spectral region 400 to 1100 nm. The monochromator uses a flat-field holographic concave grating in conjunction with an array of electronically-scanned photodiodes to measure the spectral characteristics of the films over the entire region once every 0.2 second. The data from the scans are used in the measurement and control of film thickness during deposition, but are also recorded on floppy disks so that they can be analysed afterwards, and they are now being used in the study of the behaviour of optical thin films during deposition. From these results it should be possible to calculate the profile of refractive index throughout each film yielding useful information on film structure. Methods which are used for this calculation involve as a first step the identification and measurement of extrema in the transmittance records for each wavelength permitting the calculation of the effective indices between these extrema and the eventual derivation of the refractive index profile of the films as a function of wavelength. Results which have so far been obtained for zinc sulphide are consistent with measurements of the refractive index profile made by other workers at single wavelengths, and therefore give additional support to the currently accepted models of zinc sulphide microstructure.


Usually, femtosecond spectroscopic experiments are performed in the regime of weak coupling between the chromophore and the applied laser fields. The goal of femtosecond time-resolved spectroscopy is to obtain information on the photoinduced dynamics of the molecule under study rather than to manipulate its dynamics. Nevertheless, a growing number of experimental and theoretical studies reveal that the signals induced by suitably chosen comparatively strong laser fields may provide more information on the photoinduced dynamics of polyatomic chromophores, multichromophore aggregates, and nano systems. In this talk, I will discuss recent results obtained for two different kinds of spectroscopic techniques in the regime of strong system-field coupling. We developed a theoretical description for the interpretation of double-pump femtosecond single-molecule signals with fluorescence detection and applied it to simulate signals of individual chromophores in the weakfield regime [1] and in the strong-field regime [2] This studies were motivated by the work of the van Hulst group [3]. In the second example, I will discuss the effects of strong-system field coupling in 2D electronic spectroscopy scheme. We developed a quasi-analytical method introducing the concept of nonperturbative response functions [4]. It can be shown that the nonlinear polarization representing four-wave-mixing signals can elegantly be expressed in terms of these nonperturbative response functions to all orders in the field-matter coupling. Numerical simulations of the signal are also considered for the interpretation of interesting effects of strong fields. [1]. E. Palacino-González, M. F. Gelin and W. Domcke. Theoretical Aspects of Femtosecon Double-Pump Single-Molecule Spectroscopy I. Weak-field regime. Phys. Chem. Chem. Phys., 2017, 19, 32296-32306 [2]. E. Palacino-González, M. F. Gelin and W. Domcke. Theoretical Aspects of Femtosecon Double-Pump Single-Molecule Spectroscopy II. Strong-field regime Phys. Chem. Chem. Phys., 2017, 19, 32307-32319 [3]. R. Hildner, D. Brinks, FD. Stefani, N.F. van Hulst. Electronic coherences and vibrational wave-packets in single molecules studied with femtosecond phase-controlled spectroscopy. Phys. Chem. Chem. Phys., 2011, 13, 1888 [4]. L. Chen, E. Palacino-González, M.F. Gelin and W. Domcke. Nonperturbative response functions: A tool for the interpretation of fourwave-mixing signals beyond third order. JCP, 2017, 147, 234104


Memorable tourism experience is basically about a tourism experience recollected and reviewed after the occasion has happened. It is specifically developed from tourism experiences in the light of the individual's assessment of the experience. There are lots of factor which leads to the formation of a memorable tourism experience. This article focuses on the available evidences from literature about how a memorable tourism experience is formed and what is its influence on destination image.


Property graphs are a promising data model for rich metadata management in high-performance computing (HPC) systems because of their ability to represent not only metadata attributes but also the relationships between them. A property graph can be used to record the relationships between users, jobs, and data, for example, with unique annotations for each entity. This high-volume, power-law distributed use case is a natural fit for an out-of-core distributed property graph database. Such a system must support live updates (to ingest production information in real time), low-latency point queries (for frequent metadata operations such as permission checking), and large-scale traversals (for provenance data mining). Large-scale property graph traversals are particularly challenging for distributed graph databases, however. Most existing graph databases implement a "level-synchronous" breadth-first search algorithm that relies on global synchronization in each traversal step. This traversal model performs well in many problem domains, but a rich metadata management system is characterized by imbalanced graphs, long traversal lengths, and concurrent workloads, each of which has the potential to introduce or exacerbate stragglers. We define stragglers as abnormally slow steps (or servers) in a graph traversal that lead to low overall throughput for synchronous traversal algorithms. The straggler problem can be mitigated by the use of asynchronous traversal algorithms. Asynchronous traversal has been successfully demonstrated in graph processing frameworks, but such systems require the graph to be loaded into a separate batch-processing framework. In this work, we propose GraphTrek, a general asynchronous graph traversal engine working with graph databases for processing rich metadata management in their native format. We also outline a traversal-aware query language and key optimizations (traversal-affiliate caching and execution merging) necessary for efficient performance. Our experiments show that the asynchronous graph traversal engine is more efficient than its synchronous counterpart in the case of HPC rich metadata processing, where more servers are involved and larger traversals are needed.


Choosing heavy traffic roads in Nanchong region and new districts of China West Normal university as control sites,the content of heavy metals(Pb,Cd,Cu and Zn) in leaves of different plants was analyzed.The index of air environmental pollution of plants was studied.The relationship between content of heavy metals in leaves of plants and air environmental pollution was discussed.The results show that the heavy metal concentration of Pb,Cd,Cu and Zn in the leaves of plants is significantly related with the index of pollution.The concentration of heavy metals Pb,Cd,Cu and Zn in the leaves of plants can objectively and better indicate the air environmental pollution of heavy metals.It has been proved that this method is a good way in city program and environmental protection by means of using the content of heavy metals in leaves of plants.


In contrast to prokaryotes, the proximity of genes in eukaryotic genomes has not previously been known to play any signiflcant role in their expression proflles. However, re- cently reported phenomena in human, mouse, yeast and a few plant species indicate such role: chimeric mRNAs and proteins produced via alternative transcription termination, splicing and translation of the Tail-to-Head (T2H) neighboring genes. To further verify this evidence at the genomic scale, we scanned the rice and Arabidopsis genomes for the presence of T2H gene pairs at a distance of less than 1000 bp. Our studies suggest that \non-stopping" transcription and alternative splicing of some of these T2H pairs may produce chimer transcripts. We ob- tained cDNA support for 100 Arabidopsis and 42 rice T2H pairs to be transcribed into chimeric mRNA(s). Analysis of 155 chimeric transcripts from both species revealed 71 mono-cistronic and 58 bi-cistronic mRNAs potentially encoding chimeric or separate proteins.


In the paper,the propagation approximation analytic expression and the propagation properties of hollow Gaussian beams(HGBs) through the circular aperture are studied by using the method of compound Gaussian function.The effect of the output beam caused by different radius of the circular aperture are also analyzed.The result is that the diffractive properties are relative to the order of the HGBs,the radius of the circular aperture.


Theproper interpretation of roentgenograms is one of the most valuable, if not the most valuable, aids in the diagnosis and prognosis of primary tumors of the long bones. The majority of bone tumors may be correctly diagnosed by experienced roentgenologists. However, a small percentage may baffle the most expert, even with the assistance of clinical and laboratory findings, and operation and microscopic interpretation may be necessary before a positive diagnosis can be reached. The roentgenologist should consider seriously the advisability of assuming the responsibility of making a positive diagnosis and prognosis from the X-ray examination alone. To recognize the site, size, origin, localization in, or invasion through osseous and periosseous structures, absorption or production of bone, the condition of cortex and periosteum, and to interpret these findings correctly, so as to differentiate the type of tumor, requires a very broad experience. The possibility of inflammatory lesions, tuberculosis and syp...


Abstract The Hipparcos trigonometric parallaxes of 188 blue (O-type and BO-A3 I-II) supergiants with published uvby and Hβ photometry are compared to the photomeric parallaxes of these stars based on the Mv absolute-magnitude calibration of Dambis (1990). The photometric distance scale is found to require only a minor correction −πHip = (1.03 ± 0.04)πPhot, i.e., r Hip = (0.97 ± 0.04)r Phot, which is corroborated by applying the statistical-parallax technique to a sample of 106 blue supergiants with published radial velocities and Hipparcos proper motions (r True = (0.98 ± 0.08)r Phot). The weighted mean distance-scale correction factor can thus be estimated at r True = (0.97 ± 0.03)r Phot, thereby constraining the LMC distance modulus to DM LMC = 18.36 ± 0.08 (standard error) ±0.07 (systematic error) and providing further evidence in favor of the so-called 'short' distance scale. An expanded sample consisting of 106 blue supergiants with corrected photometric distances, published radial velocities, and Hi...


Understanding changes in marine biodiversity relies on monitoring programmes that give accurate in dications of the biological response to natural and an thropogenic drivers. Historic approaches have provided poor indications of nocturnal macroinvertebrate assem blages, particularly fisheries-independent methods that rely on visual assessments of transects, or video collection devices deployed for fixed time periods. Permanent artificial habitats, specifically designed for monitoring all invertebrate species, including those that are cryptic or nocturnal, could provide an ideal solution to this critical knowledge gap. Marine Invertebrate Collection Equip ment (MICE) are artificial habitats that have been designed in Western Australia over a period of five years and are now deployed in many coastal locations where they are regularly sampled. The present study was conducted in Geographe Bay, Western Australia where replicate MICE units were deployed to determine the impact of placement on seagrass versus the standard protocol of deployment on a sandy substrate. A total of 4,403 individual macro invertebrates were collected and categorised into 104 Parataxonomic Units (PTUs), which were then aggregated into 21 intermediate classification groupings, and again into 7 broader groupings. At the intermediate level of identification, gastropods dominated the community composition, followed by worms, bivalves, sponges and am phipods. At the broader level of identification, molluscs were the most prevalent, followed by crustaceans, worms and sponges. Placement of MICE on a seagrass substrate resulted in a significantly lower abundance of invertebrates than those placed on sand (p<0.05). These differences were adequately explained using broad and intermediate levels of identification and no significant additional information was gained by identifying organisms to the level of PTU.


Robin Fox, Anthony Pateras, Lloyd Barrett and Joel Stern are artists who are influential in the Australian sound art and experimental music scenes, are interviewed. The interconnected and vibrant Australian artistic community, fertile with cross-collaboration and significantly engaged with each others work, they illustrate both the small size and artistic fertility of the Australian crossover between sound art and experimental music.


[reaction: see text]. It has been discovered that 2-O-benzyl-3,4,6-tri-O-acyl SBox glycosides are significantly less reactive than even "disarmed" peracylated derivatives. This finding has been applied to the synthesis of various oligosaccharides, the monomeric units of which are connected via cis-cis, trans-cis, and cis-trans sequential glycosidic linkages. Two-stage activation of the armed (benzylated) donor over moderately (dis)armed (acylated) and, subsequently, over disarmed (2-O-benzyl-3,4-O-diacylated) acceptor has also proven to be feasible.


Dispersion of the liquid in a porous media is of great importance in many areas of engineering and has been studied by several researchers so far. A new experimental method has been developed to measure the dispersion coefficient. X-ray absorption technique provides a better understanding of dispersion that characterizes the mixing phenomenon in the packed beds. This is because the method is non-invasive and also it gives tracer concentration data at every point within the bed. The axial dispersion in a cylindrical bed of non-porous and non-wetting spherical particles has been measured for the flow of water. Aqueous barium chloride solution has been used a as tracer. X-ray images, recorded on a videocassette, have been analyzed using an image processing software to extract the local interstitial velocity and concentration data in the bed. Local dispersion coefficient has been determined with the help of aforementioned data. By using these data, the overall dispersion coefficient in a packed bed can also be estimated.


The invention relates to network method and system. A time limit may be determined for energy efficient networking (EEN) sleep intervals based on end-to-end sleep interval limitations. The time limit may be communicated to other network devices which may limit their sleep time. End-to-end sleep interval limitation information may be received via a user input, packet header information, a standardized and/or non-standardized network management protocol, AVB, SRP, RSVP and SNMP. The EEN sleep interval time limit may be determined based on a number of hops between endpoint devices. Packets may be inspected to determine a packet data type and/or end-to-end sleep interval limitation information. The time limit may be determined based on latency requirements of data streams. A time limit for a port may be determined based on sleep time limits for data streams communicated via the port. The time limits may be statically and/or dynamically configured. The network device may be configured via a network management interface.


We propose a model-based vulnerability index of the population from Uruguay to vector-borne diseases. We have available measurements of a set of variables in the census tract level of the 19 Departmental capitals of Uruguay. In particular, we propose an index that combines different sources of information via a set of micro-environmental indicators and geographical location in the country. Our index is based on a new class of spatially hierarchical factor models that explicitly account for the different levels of hierarchy in the country, such as census tracts within the city level, and cities in the country level. We compare our approach with that obtained when data are aggregated in the city level. We show that our proposal outperforms current and standard approaches, which fail to properly account for discrepancies in the region sizes, for example, number of census tracts. We also show that data aggregation can seriously affect the estimation of the cities vulnerability rankings under benchmark models.


Abu al-Hasan Ali ibn Muhammad ibn Fahd Althamy is one of the major Arab poets and as Ibn Khalakan says most of his court is anthology of literature. His court especially includes religious-moral issues and concepts and has always been the center of attention of philosophers and researchers of moral sciences domain. Its' subjects are also debated in several religious and literary circles. He is one the most famous poets' of late fourth and early fifth century. Research in his court includes significant issues and for example we can refer to effects of Islam and Quran on its' entirety and several invitations to Islamic moralities. Also world is just a passage and since it's mortal, sudden arrival of death and god's piety should not be polluted by vices which are followed by divine torment. Since this court has been paid attention to by several researchers through different approaches and in this research, the author has tried to pay attention to his poems with a different approach which is a quick review of his moral example and traits in his poems. Author debates this issue through mentioning some evidence and also discusses the moral example of A. Althamy's poems through a descriptive analysis method.


This paper is a brief overview of the main contributions of Masaki Kashiwara in the domain of microlocal and algebraic analysis.


a of modeling experiments on the formation and development of water temperature rise during the ice-covered seasons in a large freshwater Qinghai-Tibet where lake ice processes and ice-covered lakes were less studied. very interesting that weather forcing data in Lake K were used to run the LAKE to simulate the water temperature regime in Lake Ngoring in order to investigate what causes the differences in lake temperature regimes. The paper concluded the intensive solar radiation and absence of snow dominate the development of temperature rising and the temperature rising has significant influence on after-ice-off lake-air heat exchange. Abstract: although the abstract is very long, I do not clearly get the key points on what this manuscript did, found and concluded. I suggest the authors to make the abstract more concise and more focusing. I suggest the authors follow a conventional flow line of an abstract with background, issues to be targeted, methods used, results and key conclusions.


The goal of this paper is to provide an introduction to the whistleblower protection laws that impact the FDA as well as publicly traded pharmaceutical companies. The paper begins by discussing the recent developments surrounding Mercki?½s voluntary recall of Vioxx. The discussion focuses on the fact that Merck allegedly knew of the drugs safety issues yet kept it on the market for several years, even seeking additional indications from the FDA. The paper looks at David Grahami?½s involvement as a whistleblower and examines his best avenue for redress against retaliation, the Whistleblower Protection Act of 1989. Following the discussion of the Whistleblower Protection Act, the paper considers what the options would have been were a whistleblower to come from within a pharmaceutical company instead of from the FDA. That discussion revolves around the Sarbanes-Oxley Act. I outline how and why Sarbanes-Oxley applies to pharmaceutical companies and then move to an analysis of the Acti?½s statutory language, outlining how one would bring a Sarbanes-Oxley whistleblower claim procedurally. Following this discussion, the paper gives a cursory analysis of other whistleblower retaliation statutes and issues, attempting to alert the reader that there are other avenues available and that additional considerations may be necessary, depending on the particular circumstances surrounding the retaliatory action. The paper concludes by looking at the current whistleblower climate and suggesting that the FDA may need its own whistleblower statute, particularly if courts begin to reign in Sarbanes-Oxleyi?½s currently widening scope.


Radio-frequency interference (RFI) is a serious threat for systems working with low power signals such as those coming from the global navigation satellite systems (GNSS). The spectral separation coefficient (SSC) is the standard figure of merit to evaluate the signal-to-noise ratio (SNR) degradation due to the RFI. However, an in-depth assessment in the field of GNSS-Reflectometry (GNSS-R) has not been performed yet, and particularly, about which is the influence of the RFI on the so-called delay-Doppler map (DDM). This paper develops a model that evaluates the contribution of intra-/inter-GNSS and external RFI effects to the degradation of the SNR in the DDM for both conventional and interferometric GNSS-R techniques. Moreover, a generalized SSC is defined to account for the effects of nonstationary RFI signals. The results show that highly directive antennas are necessary to avoid interference from other GNSS satellites, whereas mitigation techniques are essential to keep GNSS-R instruments working under external RFI degradation.


Residual life is of great interest to patients with life threatening disease. It is also important for clinicians who estimate prognosis and make treatment decisions. Quantile residual life has emerged as a useful summary measure of the residual life. It has many desirable features, such as robustness and easy interpretation. In many situations, the longitudinally collected biomarkers during patients' follow‐up visits carry important prognostic value. In this work, we study quantile regression methods that allow for dynamic predictions of the quantile residual life, by flexibly accommodating the post‐baseline biomarker measurements in addition to the baseline covariates. We propose unbiased estimating equations that can be solved via existing L1‐minimization algorithms. The resulting estimators have desirable asymptotic properties and satisfactory finite sample performance. We apply our method to a study of chronic myeloid leukaemia to demonstrate its usefulness as a dynamic prediction tool.


We present a new secondary school teaching method of quantum uncertainties of two-state systems. Intending to be a material teachable in schools, only two-state systems described by real numbers can be considered. An elementary argumentation based on school statistics leads to the identification of the uncertainty of a physical quantity in such systems with the standard deviation of two random variables. We provide a qualitative picture on the state-dependence of the uncertainty, leading to a pictorial representation in the form of four petals of a flower. When considering the product of uncertainty of two essentially different physical quantities we conclude that the general feature: "if the measurement of one of the quantities is certain, the other remains uncertain", cannot be faithfully expressed by means of an inequality, the product has no lower bound different from zero. The application of techniques used by school materials for teaching quantum physics leads to an exact formula for the state-dependence of the uncertainty valid in any two-state system described by real numbers, in full harmony with the qualitative picture. We compare the two-state case with the celebrated Heisenberg position-momentum uncertainty relation and show that these are both specific facets, but only the Heisenberg relation can be expressed by an inequality. The latter hardly provides any hint on the uncertainties of physical quantities in two-state systems. We conclude that the two-state approach is worth teaching in schools also in relation to the uncertainty relation, even if the Heisenberg relation is not part of the curriculum.


Micro‐ and nano‐focused synchrotron radiation techniques to investigate determinant processes in contaminant transport in geological media are becoming especially an increasingly used tool in nuclear waste disposal research. There are a number of reasons for this but primarily they are driven by the need to characterize actinide speciation localized in components of heterogeneous natural systems. We summarize some of the recent research conducted by researchers of the Institute of Nuclear Waste Disposal (INE) at the Karlsruhe Institute of Technology using micro‐ and nano‐focused X‐ray beams for characterization of colloids and their interaction with minerals and of elemental and phase distributions in potential repository host rocks and actinide speciation in a repository natural analogues sample. Such investigations are prerequisite to ensuring reliable assessment of the long term radiological safety for proposed nuclear waste disposal sites.


Although public sector organizations have long been seen as driving the institutionalization of business firms and nonprofit organizations, government agencies themselves have only occasionally been studied as subjects of institutional pressures. This research examines whether public sector organizations, when compared to organizations in the business and nonprofit sectors, are more or less as susceptible to mimetic, normative, and coercive pressures. Using data from the National Organizations Study (Kalleberg, et al., 1996), we discover that governmental organizations are in fact more vulnerable to all three types of institutional forces than other organizations, while the effect of institutional variables on for-profits and nonprofits is more sporadic. The susceptibility of public sector organizations to institutional pressures raises important questions for the field of public administration and has consequences for nonprofits and business firms, which are funded and regulated by government. Institutional Isomorphism and Public Sector Organizations Though it has not penetrated deeply into the public administration literature to date, the new institutionalism in organizational analysis has made significant contributions to our understanding of the dynamics of organizations. It has moved research away from overly rationalistic explanations of organizational behavior toward explanations that recognize that organizations are embedded in larger cultural and political contexts. It has shifted the focus of research from explaining why organizations are so heterogeneous to why organizations are so similar. Over the past decade, as its reach has extended across different topics, institutional theory has focused often on nonprofit organizations, such as art museums (DiMaggio 1991), colleges and universities (Kraatz 1998; Brint and Karabel 1991), humanitarian groups (Christiansen and Molin 1995), associations (Halliday 1993), and drug abuse units (D'Aunno, Sutton, and Price 1991). A number of studies has demonstrated the relevance of the institutional approach to for-profit organizations, including large corporations (Haunschild and Miner 1997; Davis and Greve 1997; Galaskiewicz and Wasserman 1989; Holm 1995), railroads (Dobbin 1995), law firms (Tolbert 1988), and high-tech companies (Suchman 1995; Powell 1998). Some research has also looked at public sector organizations (Tolbert and Zucker 1983; Meyer, Scott, and Strang 1987; Meyer et al. 1988.).


Collets for coupling rotary actuators to valves are disclosed. An example collet includes a first plurality of flexible members configured to be coupled to an elongated member and each having a first inner surface and a first outer surface. The first inner surface and the first outer surface define a first cross-sectional shape. The example collet further includes a second plurality of flexible members configured to be coupled to the elongated member and each having a second inner surface and a second outer surface. The second inner surface and the second outer surface define a second cross-sectional shape that is different from the first cross-sectional shape of the first plurality of flexible members. The first and the second outer surfaces are to engage a third inner surface of an opening of a lever that is configured to cause the first and the second plurality of flexible members to be displaced toward an axis of the elongated member to cause the first and the second inner surfaces to engage one or more surfaces of the rectangular shaft.


CO adsorption on clean and S‐covered Pt(111) was studied using temperature programmed desorption (TPD), electron stimulated desorption ion angular distribution (ESDIAD), LEED, and work function measurements. Special attention was paid to comparing the CO adsorption rate, binding energy, and soft bending modes on a clean surface and on p(2×2) S/Pt(111) with S coverage =0.25 S/Pt. It was found that on p(2×2) 0.25 S/Pt(111), the CO adsorption rate is decreased by a factor of 2 and only one CO adsorption state with maximum coverage, θCO ≂0.25 CO/Pt is detected. On the basis of the ESD data the CO adsorption state on p(2×2) 0.25 S/Pt(111) is assigned to terminal‐CO residing on the next nearest Pt atom and separated from S by 3.72 A. When compared with the same CO configuration on clean Pt(111) in the limit of low θCO, the adsorption binding energy of the terminal CO on sulfided Pt(111) is decreased by 8 kcal/mol. For this same overlayer, the cross sections for production of all ESD products (CO+ , O+ , and met...


Endogenous nitric oxide production modulates the pulmonary vascular tone during strenuous exercise in healthy standing horses, but it does not play a significant role in modulating the pulmonary vascular tone or the incidence of exercise-induced pulmonary hemorrhage in Thoroughbred horses. Authors' address: Depts. of Veterinary Biosciences (Manohar) and Veterinary Clinical Medicine (all other authors), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802. r 1998 AAEP.


Process auditing using historical data can identify causes for poor performance and reveal opportunities to improve process operation. To date, the data used has been limited to process measurements; however other sources hold complementary information about the process behavior. This paper proposes a new approach to root-cause diagnosis, which also takes advantage of the information in utility, mechanical and electrical data, alarms and diagrams. Its benefit is demonstrated in an industrial case study, by tackling an important challenge in root-cause analysis: large-scale systems. This paper also defines specifications for a semi-automated tool to implement the proposed approach.


We present the Prague Dependency Treebank 2.5, the newest version of PDT and the first to be released under a free license. We show the benefits of PDT 2.5 in comparison to other state-of-the-art treebanks. We present the new features of the 2.5 release, how they were obtained and how reliably they are annotated. We also show how they can be used in queries and how they are visualised with tools released alongside the treebank.


Cohort analysis is used to analyze the effects of aging and cohort succession on consumption of a product class. Cohort analysis is explained and a consumption study is reported. Strong cohort differences are found and age diffences are opposite in direction from those found by traditional methods of analysis.


Suppose that organisms occur as entities that are either singlets or doublets, that entities are able to signal to one another the presence of an observer, and that, as a result, they detect the presence of the observer according to a non-homogeneous birth process. If the behaviour of individuals (and hence their detection by the observer) is thereafter determined by a damage process, the distribution of the number of individuals seen by the observer is found to be a geometric pseudo-geometric convolution. Properties of the distribution and maximum-likelihood estimation are described. The model is shown to give a very good fit to the ruffed grouse data of GATES et al. (1968, Biometrics). Variants of the model am discussed.


In this paper, PC SAS/IML® modules are developed which calculate percentile method confidence intervals and vanants. The modules will work on distributions of parameters generated by any Monte Carlo technique, Including the bootstrap.


Ⅰ. INTRODUCTION In the past experiments on the magnetic quenching of positronium atom (a hydrogenlike bound state of positron and dectron ), the plastic scintillator and BaF_2 crystal were usually used as the detectors in the positron lifetime spectrometer. In those cases, a long light guide bet...


LaBr3 ∶Ce and LaCl3 ∶Ce which exhibit superior ability in detection ofγ-rays have been studied extensively in recent years.The properties for both of the LaBr3 ∶Ce scintillation detector and the LaCl3 ∶Ce scintillation detector were studied.The relative sensitivities to incidentγ-rays of different energy were obtained by calculation.The sensitivities of detectors to the 137Cs and 60Co sources were measured and the sensitivity ratio ofγ-ray to neutron was inspected.The result shows that the LaBr3 ∶Ce and LaCl3 ∶Ce scintillation detectors with high sensitivities toγ-rays and goodγ/n discrimination are very appropriate for measurement in the mixed field by neutrons andγ-rays.


To the Editor Senile pruritus (SP) affects elderly people with a multifactorial physiopathology. The diagnosis is made on the basis of a chronic pruritic condition and after other causes of itching, such as pruriginous dermatitis, parasitic infections and systemic diseases, have been eliminated. 1 The therapy is generally based on the so-called 'antiallergic' drugs the action of which is not entirely understood. 2


Objective:To compare various process conditions of water extraction,alcohol extraction method,enzymatic process for the instant tea preparation on soluble sugar in tea,tea polyphenols,free amino acid content.Methods:Using anthrone method,ferrous tartrate method and ninhydrin assay detected the content of tea soluble sugar,tea polyphenols,free amino acids.Results:In water extraction,alcohol extraction process of preparation of instant tea,the solid-liquid ratio,extraction temperature,extraction time were highly significant effect on the tea soluble sugar,tea polyphenols and free amino acids(p0.01).In instant tea prepared by enzymatic hydrolysis process,the enzyme combinations,enzyme dosage,reaction time,reaction temperature,solid-liquid ratio,extraction times were highly significant effect on the instant Pu'er tea soluble sugar,tea polyphenols and free amino acids(p0.01).Under optimum conditions,tea soluble sugars and free amino acid content of instant tea by enzymatic production were higher than by the water extraction and ethanol extraction.The instant tea polyphenols concentrations of ethanol extraction production were highest.Conclusion:The enzymatic production of instant tea is best.


Summary:  Incubation of human spermatozoa of normozoospermic origin with the ga‐lactose specific lectin peanut agglutinin (PNA) resulted in agglutination of the majority of sperm. This finding enabled separation of sperm into two subpopulations. The major one, accounting for 87.0 ± 12.7 (SD)% consisted of agglutinating sperm (PNA+), while the minor subpopulation (PNA‐) did not bind the lectin. The correlation between the percentages of PNA‐ sperm and acrosome‐damaged sperm, as detected by light microscopy prior to separation, was analysed and an overlapping has been found. Light and electron microscopy examination revealed that the PNA‐ cells were either acrosomeless or possessed severely damaged acrosomes while the PNA+ sperm were mostly free of such pathologies. Following treatment of sperm with fluorescin‐conjugated PNA the single cells lacked any labeling while the agglutinates exhibited fluorescence. However, the binding of the lectin to sperm was non‐uniform and differences in fluorescence intensity at various parts of the head have been observed.


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THERAPEUTIC DRUG MONITORING OF FACTOR VIII PROPHYLAXIS USING ITS PLASMA COAGULANT ACTIVITY AND GLOBAL HEMOSTASIS BIOMARKERS: A PHARMACOKINETIC/PHARMACODYNAMIC PILOT STUDY By: Maitham A. Al Hawaj, PhD (A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University.) Virginia Commonwealth University, 2012 Director: Donald F. Brophy, PharmD, MS, FCCP, FASN, BCPS Professor and Chairman Department of Pharmacotherapy and Outcomes Science I. Background: The current clinical practice of factor VIII (FVIII) prophylaxis revolves around converting patients with severe hemophilia A, hereafter simply referred to as hemophilia, phenotype (defined as plasma factor VIII coagulant activity [FVIII:C] <1 IU dL -1 ) to moderate xxi hemophilia phenotype (defined as plasma FVIII:C from 1–5 IU dL -1 ). However, a wide interindividual variation in bleeding tendency is observed despite changes in plasma FVIII:C (pharmacokinetic [PK] changes). Therefore, monitoring FVIII prophylaxis by global hemostasis biomarkers (pharmacodynamic [PD] response) can potentially be beneficial. II. Objective: To conduct appropriate PK/PD modeling using plasma FVIII:C and global hemostasis (platelet function and blood viscoelastic) biomarkers in severe hemophilia. III. Methods: Nine non-bleeding severe hemophiliacs (plasma FVIII:C <1 IU dL -1 ) with variant bleeding tendency (5 frequent bleeders and 4 infrequent bleeders) were infused with a recombinant factor FVIII (rFVIII) prophylactic dose (mean = 32.1 international units per kilogram [IU kg -1 ]). Blood was collected at baseline and 0.5-, 1-, 2-, 4-, 8-, 12-, 24and 48-hours (h) post-dose for plasma FVIII:C, platelet function (platelet contractile force [PCF], clot elastic modulus [CEM] and force onset time [FOT]) and blood viscoelastic (reaction-time [R], kineticstime [K] and maximum amplitude [MA]) biomarkers and activated partial thromboplastin time (aPTT). Non-compartmental analysis (NCA) was performed using standard methods. Compartmental analysis (CA) and PK/PD modeling were performed by non-linear regression. Correlation and analysis of variance (ANOVA) were used to explore the role of clinically relevant modifiers of bleeding tendency, as appropriate. ANOVA was used to assess inter-group differences in pertinent PK and PD parameters. P value <0.05 significance level was prespecified for all statistical tests. xxii IV. Results: Mean (±SD) volume of distribution at steady state (Vss), total clearance (CLtot) and terminal half-life (t1/2) from NCA were 40.5 (±11.2) milliliter per kilogram (mL kg -1 ), 2.9 (±1.2) milliliter per hour per kilogram (mL h -1 kg -1 ) and 11.6 (±6.2) h, respectively. Mean (±SD) Vss and CLtot from the one-compartment body model (CA) were 39.6 (±8.9) mL kg -1 and 3.1 (±1.3) mL h -1 kg -1 , respectively. The mean (±SD) baseline effect (E0) and slope from the PK/PD linear modeling were: for aPTT, 48.9 (±4.4) seconds (sec) and -0.025 (±0.009) second deciliter per international unit (sec dL IU -1 ), respectively; for PCF, 0.3 (±0.3) kilodynes (kdynes) and 0.008 (±0.004) kilodynes deciliter per international unit (kdynes dL IU -1 ), respectively; and for CEM, 0.0 (±0.0) kilodynes per square centimeter (kdynes cm -2 ) and 0.032 (±0.016) kilodynes deciliter per international unit per square centimeter (kdynes dL IU -1 cm -2 ), respectively. The mean (±SD) maximum effect (Emax) and half the maximum effective concentration (EC50) from the PK/PD sigmoidal Emax model were: for FOT, 70.1 (±16.9) % reduction and 87.8 (±31.4) IU dL -1 for FOT, respectively; for R, 74.9 (±26.0) % reduction and 68.5 (±28.4) IU dL -1 , respectively; and for K, 73.2 (±36.4) % reduction and 67.2 (±29.0) IU dL -1 , respectively. MA was not PK/PD modeled due to its low sensitivity. V. Conclusions: Plasma FVIII:C remained ≥1 IU dL -1 over the prophylactic interval. FOT and R were the most sensitive biomarkers at lower plasma FVIII:C. PCF and CEM were more sensitive than K and aPTT at lower plasma FVIII:C. MA was the least sensitive biomarker. Correlation and intergroup differences did not reach statistical significance (small sample size). These results may be used to assess risk of bleeding and dose-optimize FVIII prophylaxis in severe hemophilia. 1 CHAPTER 1. BACKGROUND 1.1. HEMOPHILIA A: 1.1.1. Definition and Epidemiology of Hemophilia A: Hemophilia A or classic hemophilia, hereafter simply referred to as hemophilia, is a coagulation disorder that is caused by a recessive X-linked deficiency of FVIII. [1–3] The mutant X-chromosome is expressed in males and carried in females, making hemophilia a disease of males with carrier females. [1–3] In 2009, the prevalence of hemophilia was 115,204 males in 105 countries. [4] The mean global per capita usage of FVIII, the blood coagulation factor replacement therapy used in hemophilia, was 2.02 international units ( IU) in 2009. [4] The total annual global FVIII consumption was 7,333,984,513 IU for the same year. [4] Hemophilia is found in all ethnic groups worldwide. [1] 1.1.2. Pathophysiology of Hemophilia A: Males with hemophilia have the defective allele on the X-chromosome without a matching allele on the Y-chromosome while carrier females have only one defective allele. [1] Sons of a father with hemophilia would be normal if the mother is not a carrier; however, daughters would be mandatory carriers (Figure 1.1 ). [1] If the father does not have hemophilia, sons and daughters of a carrier mother would have 50% chance of being hemophiliacs and carriers, respectively (Figure 1.1). [1] Therefore, there is a skipped generation inheritance pattern with hemophilia in which carrier females do not exhibit the disease but can transmit the defective 2 X-chromosome to the next male generation, who exhibit the disease. [5] Sons of a father with hemophilia and a carrier mother have 50% chance of being hemophiliac whereas daughters would be either hemophiliacs (very rare) or carriers (Figure 1.1). [1,6] The pathophysiology of hemophilia on the molecular level includes mutation in the FVIII gene that encodes FVIII. [2] Several mutations in the FVIII gene have been documented, including point mutations, deletions and insertions. [2] The most common mutation in the FVIII gene is intron 22 inversion. [2] The intron 22 inversion accounts for about 50% of severe hemophilia abnormalities. [2] Another common mutation in the FVIII gene is intron 1 inversion. [2] The intron 1 inversion accounts for about 5% of severe hemophilia abnormalities. [2]


The present work describes, for the first time, the simultaneous separation of oxcarbazepine (OXC) and its active metabolite 10‐hydroxy‐10,11‐dihydrocarbamazepine (licarbazepine, Lic) by chiral CE. The developed method was employed to monitor the enantioselective biotransformation of OXC into its active metabolite by fungi. The electrophoretic separations were performed using 10 mmol/L of a Tris‐phosphate buffer solution (pH 2.5) containing 1% w/v of β‐CD phosphate sodium salt (P‐β‐CD) as running electrolyte, −20 kV of applied voltage and a 15°C capillary temperature. The method was linear over the concentration range of 1000–30 000 ng/mL for OXC and 75–900 ng/mL for each Lic enantiomer (r ≥ 0.9952). Within‐day precision and accuracy evaluated by RSD and relative errors, respectively, were lower than 15% for all analytes. The validated method was used to evaluate the enantioselective biotransformation of OXC, mediated by fungi, into its active metabolite Lic. This study showed that the fungi Glomerella cingulata (VA1) and Beuveria bassiana were able to enantioselectively metabolize the OXC into Lic after 360 h of incubation. Biotransformation by the fungus Beuveria bassiana showed 79% enantiomeric excess for (S)‐(+)‐Lic, while VA1 gave an enantiomeric excess of 100% for (S)‐(+)‐Lic. This study opens a new route to the drug (S)‐(+)‐licarbazepine.


The purpose of this study was to describe the optimization of culture in multicultural education in
Indonesia. Various cultural issues grow and develop in the Indonesian community in line with changing times.
This can be demonstrated by the increasing ethnocentrism that shifts the values of nationalism, the shift of local
culture values by global culture, the changes in lifestyle and the increasing loss of mutual cooperation culture in
the community, and the increasing individualistic attitudes in the community, and so on. In addition, the
imposition of custom and culture by groups on other groups, the increasing number of ethnicities, the weakening
of national integration, self-righteousness, and so on are various cultural issues in the community. If not
managed properly, these differences will become a boomerang in the form of prolonged conflict, because
multidimensional community structure of Indonesia is a problem for integration efforts and processes. Cultural
conflicts occur due to inconsistencies, differences in interests, and differences in beliefs. Conflicts arise because
of differences between individuals or communities which is very likely to occur in Indonesian communities.


This research seeks to better understand how rural elders receive assistance from family members while still maintaining a sense of autonomy. In-depth interviews with rural elders explored both assistance and autonomy. Results indicate that rural elders are able to receive assistance from family members while maintaining autonomy through a range of strategies, including purposefully giving over control to others when needed and relinquishing control before it is taken away. Lessons learned here guide formal service providers to permit elders to direct their own care planning and implementation, thereby allowing them to maintain a level of autonomy.


This study examines the potential of constructive journalism ideas and their implementation in Croatia, a country with a different social, cultural and historical background than that of Denmark or other Western European countries where constructive journalism is practised. Three Croatian linguists explain the potential hidden meanings of the word constructive for Croatians. Fifteen broadcast journalists and editors in Croatia have been interviewed in order to examine the potential opportunities and obstacles for the implementation of constructive journalism ideas in their newsrooms. Croatian journalists have a more active approach towards journalism and their overall impression of constructive journalism ideas is positive. Both linguists and journalists noticed potential ideological connotations of the word constructive, while journalists were careful about reporting on possible solutions and things that would work so as not to cross the line and be pulled into ideology. When it comes to implementation, most journalists point out differences in mindset, political influences and newsroom routines as main obstacles. A development of a specific strategy for Croatian newsrooms that moves away from adhering to ideas only is recommended, while the word constructive may be used only if it is clearly defined.


Performing measurements in reacting flows is a challenging task due to the complexity of measuring all quantities of interest simultaneously or limitations in the optical access. To compensate for this, recent advances in deep learning have shown a strong potential in augmenting the
 information content in datasets composed of partial measurements by reconstructing the quantities that could not be measured. The present work analyses the use of such deep learning tools for the reconstruction of quantities in two different cases. First, Convolutional Neural Networks (CNNs)
 are used to reconstruct the heat release rate (HRR) from velocity measurements in a methane/air premixed flame under harmonic excitation. The CNNs are trained from complete datasets at some specific frequencies and amplitudes of excitation and their ablility to reconstruct the HRR for different
 operating conditions with good accuracy is demonstrated. Secondly, an alternate approach based on Physics-Informed Neural Networks that do not require the training data to have all the quantities is explored. It is applied to a puffing pool fire where the velocity field is reconstructed from
 observations of pressure, temperature and density with good accuracy. Both approaches are also shown to be robust with respect to noise.


Objective: A Scorpion sting is one of the most important health and medical problems in most parts of Iran. Case Presentation: This case report occurred in Chaharmahal Bakhtiari province of Bazoft city. The injured person was a 48-year-old woman, weighing about 69 kg. Two documentary filmmakers were on their way to work and suddenly one of them felt pain caused by a sting in the thigh area of her lower limb. The patient was referred to the medical center with the 'scorpion' sample, where she was examined by a doctor. The doctor prescribed some medicine for the patient. The pain from the sting lasted for about three hours. The patient recovered after taking the medication and received counseling three days after the sting. A photo of the dorsal and ventral surface of the scorpion specimen was sent to the animal identification specialist along with the size and color record. Scorpion specimen with a size of 4 cm was identified as Compsobuthus matthiesseni. Conclusion: According to the findings of this report, the clinical signs of C. matthiesseni sting are mild in the injured person and comparable to the stings of yellow bees Vespa germania. There is local pain two to three hours after the sting. Other systemic clinical manifestations can improve after a maximum of 2 to 3 days.


The findings of a study of motorists' perceptions of exclusive/permissive (E/P) signal phasing at 10 intersections in Virginia are presented. Traffic volumes and conflict rates were counted at each site and accident files were investigated. In addition, 1,252 residences and small businesses in the vicinity of the sites were sent questionnaires to determine motorists' opinions and perceptions of E/P phasing. A total of 460 completed questionnaires were received and analyzed. Roughly one-third of those queried were confused by the E/P signal the first time they encountered it, but the confusion dissipated over time. Advance publicity of an E/P signal modification or installation and an explanatory sign placed adjacent to the signal head will do much to reduce motorists' confusion. More than 70 percent of those surveyed wee in favor of E/P signal phasing and 77 percent thought that it reduced intersection delay. Onsite observations revealed that vehicular conflicts at E/P intersections are most frequent at locations that have high volumes of turning vehicles and various movements of traffic. The conflict rate could not be attributed to any one characteristic of an intersection, however. The same was true for the accident rate. (Author)


'…more citizens… receive their justice from agencies than the courts' (Chitra: 3). The last 30 years of administrative law practice in Australia have been characterised by the proliferation of tribunals and other bodies engaged in quasi-judicial work. These organisations have developed on a largely ad hoc basis, particularly at the state and territory level. Despite this rapid growth – or perhaps as a result of it - a clear articulation of the underlying practice principles pertinent to tribunals has yet to occur in any coherent fashion. This thesis canvasses the current mechanisms used to assist tribunal members in their work, including legislative and ethical parameters. The argument is then mounted that more guidance is needed in relation to the normative excellences of the tribunal member's role. An analysis of the systemic and cultural challenges faced by the sector is presented, highlighting the lack of sector definition, disparate practices, resource limitations and institutional isolation that characterise Australian tribunal work. Canadian and United Kingdom experiences provide a useful context for Australian impediments and developments. A state-based merits review body is used as a case study throughout the thesis to illustrate these issues. It is posited that greater emphasis upon the philosophical underpinnings of tribunal practice will assist in improving cohesion among sector members, leading to enhanced delivery of administrative justice. A stance from virtue ethics is adopted as a starting point for this endeavour, on the basis that improved decision-making commences with close analysis of the excellences defining the tribunal member's role. This aretaic approach highlights the importance of 'practical wisdom' or phronesis in tribunal work. Methods for implementing and enhancing discussion of relevant tribunal practice principles are then examined, with various innovative legal training tools being nominated as particularly useful in the tribunal context. The tribunal sector is generally seen to have operated adequately to date. A more normative approach to decisionmaking excellence within the tribunal field is required, however, with this thesis forming the staring point of such analysis.


fections, mould infections, infections due to dimorphic fungi, cutaneous infections, infections in compromised hosts, and other mycoses. The target audience appears to be physicians who are interested in infectious diseases and fungal infections, trainees in infectious diseases and internal medicine, and medical students. The book is well written and includes detail that will satisfy people with varying levels of knowledge. It will serve as the ultimate textbook reference for questions related to diagnosis and treatment of fungal infections. Epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment are reviewed for all fungal pathogens, including those that are rare. All of the chapters are extensively referenced and up-to-date. Many of the chapters provide the reader with definitive recommendations for therapy. A good example of this is the chapter on cryptococcosis, which has 2 excellent tables of recommendations for treating patients with cryptococcal disease, one table for patients infected with HIV and the other for patients who are not. Other chapters discuss treatment options, but the author does not rank them. This is particularly the case for diseases that are less common, where data from controlled clinical trials are not available. In that circumstance, expert opinions as to the recommended management would be welcomed. Finally, several important studies of the treatment of fungal infections, particularly aspergillosis and candidemia, were published about the time that the chapters in this book were being written. They are mentioned, but the results are not well integrated in the management recommendations. In summary, this book can be recommended to all physicians interested in the treatment of fungal infections. It is informative and provides a sound basis of knowledge for diagnosis and treatment of fungal infections. As the field continues to move forward, supplementation of this book with key research papers will allow clinicians to provide state-of-the-art therapy to their patients.


Logic is an ancient discipline that, ever since its inception some 2500 years ago, has been concerned with the analysis of patterns of valid reasoning. Aristotle first developed the theory of the syllogism (a valid argument form involving predicates and quantifiers), and later the Stoics singled out patterns of propositional argu- mentation (involving sentential connectives). The study of logic flourished in ancient times and during the middle ages, when logic was regarded, together with grammar and rhetoric (the other two disciplines of the trivium), as the foundation of humanistic education. Throughout its history, logic has always had a prescriptive as well as a descript- ive component. As a descriptive discipline, logic aims to capture the arguments accepted as valid in everyday linguistic practice. But this aspect, although present throughout the history of the field, has since the inception of the modern con- ception of logic, some 100 or 150 years ago, taken up a position more in the background, and in fact some have argued that it is no longer part of logic proper, but belongs to other disciplines (linguistics, psychology, or what have you). Nowadays logic is, first and foremost, a prescriptive discipline, concerned with the identification and justification of valid inference forms. The articulation of logic as a prescriptive discipline is, ideally, a two-fold task. The first task requires the identification of a class of valid arguments. The class thus identified must have certain features: not just any class of arguments will do. For instance, it is reasonable to require that the class of valid argument be closed under the relation "having the same logical form as," in that if an argument is classified as valid, then so is any other argument of the same logical form. It is clear, then, that such an identification presupposes, and rests on, a notion of logical form. The question of what constitutes a good theory of logical form exceeds the boundary of the present contribution, and hence we will not be concerned with


Aim and Objectives: The present study was undertaken to compare the efficacy and safety of dexmedetomidine versus nitroglycerin in maintaining intraoperative haemodynamic stability and postoperative recovery profile in adult patients undergoing posterior fixation surgery for traumatic spine injuries.Methods: The study enrolling 60 patients of either sex (age 18-50 years), ASA grade I and II were randomly allocated into two groups of thirty patients each. Group DEX received dexmedetomidine 1?g/kg infusion (diluted in 50 ml of 0.9% normal saline) and group NTG received 50 ml of 0.9% normal saline infusion over a period of 10 min as bolus before premedication. The intraoperative haemodynamic parameters, estimated blood loss, operative time, intra and post operative complications, post operative sedation and recovery in patients were noted and compared between two groups.Results: Dexmedetomidine had better intraoperative haemodynamic stability than nitroglycerine, (p<0.05). The mean blood loss and duration of surgery was less with dexmedetomidine than with nitroglycerin, (p<0.01). Dexmedetomidine has fewer episodes of complications viz; tachycardia, bradycardia, hypotension and hypertension during and after surgery as compared to nitroglycerin. Post operative sedation was more with dexmedetomidine as compared to nitroglycerin, (p<0.05). Conclusion: Dexmedetomidine is an effective and safe agent in maintaining intraoperative hemodynamics in adults undergoing posterior fixation spine surgery.


We have studied the performance of rod-pinch diodes with heated anodes. Anode heating is seen to virtually eliminate the proton component of the ion beam, leading to an increase in radiation efficiency. With heated anodes the beam pinches slightly closer to the rod tip which leads to a reduction in spot size when tapered anodes are used. An expected reduction in the rate of impedance collapse is not observed. Heating is easy to implement, and the observed improvements in diode performance merit further study of this approach.


In the early twenty-first century, environmentally friendly accounting practices in the creative industries were confined to site-specific budgets of individual films or studio operations. Any external environmental costs were either ignored or written off as too hard to measure. This chapter considers the media's future by imagining a new kind of accountancy freed from the bonds of corporate media. Richard Maxwell and Toby Miller have devised an imaginary world where accountants, imbued with the values of green citizenship, set off on a quest to uncover the environmental and labor conditions within the global supply chain of consumer electronics and information and communication technologies. This speculative fiction helps the authors conjure up conditions in which media producers and media studies scholars address human-centric despoliation of the Earth's ecosystems and the toxic exploitation of media workers.

Keywords:

Environment;
Ecological;
Cultural Labor;
Exploitation;
E-Waste;
Accountancy;
Accountants;
Media;
Information and Communication Technology;
Consumer Electronics;
Supply Chain;
Ethics


Recently, while attending a reunion of my college graduating class, I got into a conversation with a former classmate of mine regarding the subject of peer review of journal manuscripts. My friend questioned the need for peer review, instead advocating a system whereby authors would post manuscripts on a website and readers would post reviews and critiques much as one presently does with websites such as TripAdvisor. He noted several advantages of such a system. First, manuscripts would be made available for dissemination much more rapidly than they are under peer review. The JACMP presently averages about six months from submission of a manuscript to acceptance, with another three months or so until publication. This time period includes the time it takes for the referees to prepare their reviews of a manuscript, for an author to respond to the reviewers' comments and revise the manuscript in response to the reviewers' comments, and for the referees to review the manuscript a second time. Sometimes a manuscript goes through a third or even fourth round of review, further increasing the time lag from submission to publication. If there were no review, a manuscript could be posted immediately, and the information presented in the manuscript could be shared with the readership community much more rapidly. The second advantage of such a system is the democratization of the review process. Every reader of a manuscript would become a potential reviewer, allowing for a variety of opinions as to the relative strengths, weaknesses, and utility of a manuscript. Instead of the reviewers being an "elite" class of experts, all medical physicists who read the manuscript would have the opportunity to provide input into the review process. My friend raised some valid points and, in fact, the idea of open review has been proposed for this, as well as for other, journals. Moreover, when I travel, I often take advantage of TripAdvisor for various travel recommendations. However, medical physics manuscripts are not hotel or restaurant recommendations, and I remain an advocate for peer review for the following reasons:


An Investigation Into the Effects of a Training Program Upon Leaders of Educational Innovations (September 1980) Nancy Moonan Spencer, B.S., Wheelock College M.Ed., University of Massachusetts Ed.D., University of Massachusetts Directed by: Professor Masha Rudman Self-direction has been articulated as the aim of education by educators and psychologists alike. This is because it is believed that self-directed individuals are better prepared to face the uncertainties of a constantly changing world. They have learned how to learn, how to engage in change and to continue to grow. Self-directed learners exhibit these characteristics as they choose their own educational objectives, and then plan, implement, and evaluate their own learning outcomes. Since self-directed learning is a valued aim of education, educators must begin to examine the characteristics of a self-directed individual and the environments which encourage self-directed learning. What enables an individual to become engaged in self-directed learning? What motivates a person to take such initiative and control over his/her own learning? How do such individuals view themselves? How do they accept new experiences? What are the learning environments and interactions with others that foster self-directed learning? Is there a conceptual framework for designing learning experiences that can increase selfdirected learning in adults? Can this conceptual framework be taught vi to leaders of adult learning experiences through active participation? This dissertation is an investigation into the effects of the 1978-1979 Hampshire Educational Collaborative Title IVc Training Program. This program used the following set of beliefs concerning inservice education both in creating the program's design and in its implementation. The statements are derived from an examination of the literature on what environments encourage self-direction. Participants' personal needs and interests are identified and utilized. A physical and psychological climate conducive to learning must be provided. Lower order needs (food and drink) must be met before higher order needs (cognitive, self-actualizing). 2. Participants should be involved and share in the planning, implementation and evaluation of their own learning experiences. They should be actively involved in solving real problems. 3. Participants respond positively to the opportunities to work from their strengths . Participants and leaders should have an awareness of and use a variety of resources to meet personal and professional goals. 4. Participants seem better able to apply new learning, refine their skills, and continue growing as they get feedback and support from others in the form of a helping relationship . The goal of the training program was the development of selfdirected learners and the training of the participants in inservice program practices that promote self-directed learning. The dissertation examines the humanistic view of a self-directed individual and the environments which foster self-directed learning. The self-directed learner behaviors and the environments which encourage self-directed learning identified in this study are used in qualitative evaluations of vii qualitative the effects of the training program. The results of the evaluations highlight what components of the conceptual framework used in the design of the program actually do affect the participants' selfdirected learning behaviors . This dissertation also provides educators with insights on how to train leaders of inservice programs in the application of the identified set of beliefs. Two evaluation methodologies are used in this study to measure changes in the participants' utilization of the beliefs concerning inservice programs. The analysis of the participants' responses to the Beliefs Inventory, a quantitative instrument developed for this study , and the analyses of the qualitative data present educators with information on the extent to which participants implemented these beliefs in their leadership of adult learning experiences. The results of these evaluations emphasize which beliefs can be changed when individuals are actively involved in planning, implementing and evaluating a series of adult learning experiences . The study concludes with a synthesis of the results of the qualitative and quantitative evaluations, presents suggestions for training programs with similar goals , and recommendations for further research.


Human face perception is currently an active research area in the computer vision community. Skin detection is one of the most important and primary stages for this purpose. So far, many approaches are proposed to done this case. Near all of these methods have tried to find best match intensity distribution with skin pixels based on popular color spaces such as RGB, HSI or YCBCR. Results show that these methods cannot provide an accurate approach for every kind of skin. In this paper, an approach is proposed to solve this problem using a color probabilistic estimation technique. This approach is including two stages. In the first one, the skin intensity distribution is estimated using some train photos of pure skin, and at the second stage, the skin pixels are detected using Gaussian model and optimal threshold tuning. Then from the skin region facial features have been extracted to get the face from the skin region. In the results section, the proposed approach is applied on FEI database and the accuracy rate reached 99.25%. The proposed approach can be used for all kinds of skin using train stage which is the main advantage among the other advantages, such as Low noise sensitivity and low computational complexity.


(57) by a method comprising administering in conjunction with an effective amount of PEG interferon -α an Abstract effective amount of ribavirin, have patients with chronic hepatitis C infection, for example, an HCV genotype 2 or 3 the use of ribavirin and interferon -α for the manufacture of a pharmaceutical composition for eradicating detectable HCV-RNA by treating the patient, two treatment periods :( patients with chronic hepatitis C infection a) is at least substantially reduce the detectable HCV-RNA, preferably sufficient to eradicate, therapeutically effective amount of ribavirin and PEG interferon-.alpha. therapeutically effective induction dose, for example PEG interferon-.alpha.-2b first treatment period of at least 20-30 administering and (b) after the end of at least 20 to 30 of the first treatment period To maintain that no weekly detectable HCV-RNA, and sufficient to maintain the second no at least 24 weeks detectable HCV-RNA after the end of the treatment period a therapeutically effective amount of ribavirin and whereby said treated to at least 20 to 30 weeks of the second treatment period administering a PEG interferon -α therapeutically effective amount is disclosed.


Objective
To evaluate the safety and feasibility of totally laparoscopic total gastrectomy(TLTG) in the radical surgery of proximal stomach cancer.

Methods
Data of 81 patients undergoing TLTG surgery for proximal gastric cancer from Jan. 2018 to Jun. 2019 in Hangzhou First People′s Hospital Affiliated to Medical College of Zhejiang University were retrospectively analyzed.

Results
81 patients completed the TLTG, and no cases were transferred to laparotomy. The average operation time was (211±22.4) min, the average intraoperative blood loss was (78±27.2) ml, the average lymph node dissection was(26.3±3.8), the total positive lymph node rate was 29.6%(24/81), and the splenic hilar positive lymph node rate was 8.1%(3/37), the superior pancreatic region (No.7/8/9 lymph node) positive lymph node rate was 21.0%(17/81), the average postoperative exhaust time was(2.3±0.8)d, and the average postoperative hospital stay was (9.1±3.2)d. One patient developed anastomotic fistula after operation, which healed after conservative treatment with double cannula irrigation; 4 patients developed esophagojejunal anastomotic stenosis after operation, which improved after conservative treatment, and no complications were observed in the rest patients.

Conclusions
TLTG is safe and feasible in radical surgery for proximal gastric cancer.

Key words:
Totally laparoscopic total gastrectomy; Complete laparoscopic surgery; Gastric cancer; Lymph node dissection around the common hepatic artery; Overlap anastomose


The neuroscience research is gaining momentum and it explores the science of brain and performance of an individual. Whole Brain Teaching (WBT) is a blend of direct instruction and cooperative pedagogy that allow teachers to effectively deliver the lesson and to create an engaged and enjoyable learning experience for the children. This study aimed to investigate the effectiveness of whole brain teaching on learning Math and its impact on positive and negative learning behaviors of the children in Math classroom. The study adopted single group pre-test post-test experimental design and 30 six-years-old preschool children participated in the study. The data were collected using Math tests and observations. Math lessons on addition was considered to explore the effectiveness of WBT. Before the intervention, addition problems were taught using traditional teaching method and the children completed the pre-test. The five different WBT fun filled strategies were taught to the children prior to the intervention. This was followed by teaching addition using whole brain teaching which incorporates the WBT strategies. The paired t-test results revealed that the children scored high in WBT intervention (M=7.23, SD =1.40) compared to the traditional teaching (M=4.70, SD=2.21) and that there was a significant difference between the test scores before and after the treatment (t (29) = 5.517, p < 0.001). This concluded WBT enhances Math learning among early learners. Further, to study the impact of WBT on the engaged learning, 6 children learning behaviours were recorded and analysed. A tally sheet of positive and negative learning behaviours was used to record their behaviours. Three observations before and after the treatment were considered for the study. The results confirmed WBT increases the positive and decreases the negative learning behaviours. The study recommends the early childhood educators to teach Math using whole brain teaching for improved performance and engaged learning of the children.


Surface-enhanced Raman scattering (SERS) is an effective characterization method which has shown broad applications in the field of detection and identification. In this work, we describe the facile fabrication of SERS ultrathin films (UTFs) based on a two-dimentional architecture via layer-by-layer assembly of hygroscopic sodium polyacrylate (PAAS) modified Au nanoparticles (NPs) and MgAl layered double hydroxide (LDH) nanosheets. The resulting Au@PAAS/LDH UTFs possess a periodic long-range ordered layered structure and dense immobilization of Au NPs within the LDH interlayer microenvironment. The distance of Au NPs in the x–y plane reaches as low as ∼2.16 nm, and thus the coupling of Au–Au NPs enabled an enhanced electromagnetic field and improved SERS effect. For example, a detection limit as low as 10−9 M could be obtained for Rhodamine 6G. Moreover, the obtained UTFs could be adapted to various solvents and dye molecules, confirming the versatility and the sensitivity of the 2D UTFs. In addition, the UTF exhibits satisfactory reusability and high stability at high temperature and various pH values. Therefore, this work highlights a high-efficiency SERS film material with facile preparation, which guarantees their further application in environmental detection and analysis.


(a) Exit-site infections: Exit -site infections may appear at any time during the management of a CAPO patient. In this respect, they are unpredictable and do not appear to be connected with simple breaks in sterility. Although Staph. aureus is the most common organism, a whole host of other microbial agents can be isolated from the infected exit site. The pathogenic mechanism is not quite clear . Mechanical irritation, hypersensitivity to the silicone rubber, hyperhydrosis and reduced tissue reactivity all may playa role in the development of this complication. Clinically, these infections may present with a spectrum varying from slight redness around the catheter, to a deep ulcerated erosion producing copious amounts of pus. Symptoms of pain and fever are rare. For microbiological identification of the causative organism, cultures should be taken from the purulent site rather than the skin, since often the causative organism(s) are nonnal skin saphro


This article emphasizes the optimization of processing parameters required for the blending of polyether-based thermoplastic polyurethane (TPU) and poly dimethyl siloxane (PDMS) rubber. Taguchi methodology was adapted as a statistical tool in the design of experiment to optimize processing conditions on the basis of tensile strength and impact strength for 50:50 blend of TPU and PDMS. L9 (33) orthogonal array strategy was utilized for conducting the experiments. The experimental data were transformed into signal-to-noise ratios, based on which each processing parameter has been optimized. Measure of confidence of the results has been studied using standard statistical technique of analysis of variance. From the results, the processing conditions have been optimized.


Climate change is expected to have considerable impacts on marine life and marine
ecosystems. There will inevitably be flow-on implications for human societies and
economies, particularly those in regional Australia highly dependent on the marine
environment and its resources


Alan Hodgkinson, founder of SoftXS GmbH, explains issues associated with selecting a drawing management system (DMS) and listes the main requirements they should fulfil.


Polypropylene (PP) and polylactic acid were blended in the ratio 80:20 by weight and compatibilized with 3 wt% of maleic anhydride-grafted-PP. The compatibilized blend was chosen as the base matrix for reinforcement with halloysite nanotubes (HNTs). The nanotube content varied from 0 to 10 wt%. Blend and the nanocomposites were prepared by melt mixing technique. Dielectric analysis of the base matrix and the nanocomposites was carried out using interdigitated electrode sensor in a DEA 288 Epsilon-dielectric analyser. The dielectric properties of the composites were measured at temperatures from 30 to 120°C at various frequencies ranging from 1 Hz to 1 kHz. Permittivity values slightly decreased as the HNT content increased from 0 to 2 wt%. It increased at 4 wt% of HNT and again slightly decreased at 6 wt% of HNT, and with further increase in HNT (HNT 8 and HNT 10) led to increase in permittivity values. Loss factor values decreased slightly as the HNT content in the composites increased from 0 to 4 wt%; but with further increase in HNT, the loss factor showed a sharp increase. Loss tangent (tan δ) values decreased up to 4 wt% of HNT (HNT 4) and then increased up to 8 wt% (HNT 8) of HNT and then decreased slightly (for HNT 10). Analysing the different dielectric properties, consistent properties were shown by 6 wt% of HNT similar to static and dynamic mechanical properties. The analysis showed that the composites can be utilized in microelectronic devices or in microelectronic packaging applications.


In Escherichia coli, initiation of translation for mRNAs is known to be promoted by the binding of the 3' end of 16s ribosornal iZNA (rRNA) to a purine r i c h sequance ('nnown as ShineDalgarno sequence, S D ) 5' to the initiator codon (AUG) . Using an E.coli expression system w e have proposed the presence of alternative sites (loops 42 and # 43, and nucleotides 458-467) on the 16s rRNA capable of binding functional M A S . We have also shown that the 5 ' untranslated regions of clover yellow mosaic virus and papaya mosaic virus RNA genomes are both capable of initiating translation in E.coli.


Iterative solvers are widely regarded as the most efficient way to solve the very large linear systems arising from finite element models. Their memory requirements are small compared to those for direct solvers. Consequently, there is a major interest in iterative methods and particularly the preconditioning necessary to achieve rapid convergence. In this paper we present new element‐based preconditioners specifically designed for linear elasticity and elasto‐plastic problems. The study presented here is restricted to simple associated plasticity but should find wide application in other plasticity models used in geotechnics. Copyright © 2006 John Wiley & Sons, Ltd.


We present here, as an integration target example, a simple BPSK TX PIC [1]. Its operation principle relies on two-arm inteferometric waveguide arrangement with optical phases 0-π prefixed by 1:2 MMI power splitter and DC-current controlled phase shifters. The waveguides are then combined in 2:1 MMI into a single output. Three different active regions made of AlGaInAs MQWs are defined in a single SAG epitaxial step by use of dielectric masks. Fig 1 shows the simulated photoluminescence wavelength for each photonic function area of a 1.5μm BPSK chip [2]. In 1.3μm designing we focus first on efficient laser and EAM as the most critical functions to integrate.


It is well-established that the heterodiatomic free radical, nitric oxide (NO), is a crucial component in many biological repair processes, although the exact mechanism of action has not yet been elucidated. When delivered directly to a particular site, blood flow can be enhanced and the healing process accelerated. Conditions that can benefit from topical nitric oxide therapy include: diabetic ulcers, peripheral neuropathy or other disease states resulting from vascular insufficiencies, cold hand and feet syndromes, and transdermal drug delivery where the diffusion rate is slow. Researchers have sought various ways to deliver NO therapeutically to damaged tissue. Diazeniumdiolates (NONOates) exhibit the ability to deliver NO spontaneously. Previous work by Smith, et.al. has shown that polymeric NONOates have been used for controlled release of NO to a specific site (USP 5,519,020; 6,737,447; 6,855,366). Thus, therapeutic levels of nitric oxide could be delivered in a controlled manner to tissues and organs to benefit the healing process and to prevent injury to tissues at risk.


The grid connection of large-scale wind power will reduce the equivalent inertia and damping of the system, resulting in a decrease in system frequency stability. The directly-driven permanent magnet synchronous generators (D-PMSG)-based wind turbine (WT) usually uses conventional PD control to support frequency, however, the related controller parameters are difficult to design, reducing economic benefits of WT power generation and slowing speed recovery. To this end, based on the analysis of the dynamic response of D-PMSG grid-tied system, this paper studies the dynamic influence and variation law of controller parameters on system frequency. A WT control strategy based on frequency trajectory planning (FTP) is proposed. The frequency fixed value determined by the power grid regulation is directly taken as the control target to carry out the FTP, and the WT auxiliary power output is controlled according to the planned frequency trajectory. The system frequency is supported quickly in the transient process, ensuring the safe and stable operation of the grid while realizing the economy of WT power generation. The effectiveness and economy of the proposed control strategy is verified by RT-LAB experiment.


We demonstrate a spectrum demodulation technique for greatly speeding up the data acquisition rate in scanning nitrogen-vacancy center magnetometry. Our method relies on a periodic excitation of the electron spin resonance by fast, wide-band frequency sweeps combined with a phase-locked detection of the photo-luminescence signal. The method can be extended by a frequency feedback to realize real-time tracking of the spin resonance. Fast scanning magnetometry is especially useful for samples where the signal dynamic range is large, of order millitesla, like for ferro- or ferrimagnets. We demonstrate our method by mapping stray fields above the model antiferromagnet $\alpha$-Fe$_2$O$_3$ (hematite) at pixel rates of up to 100\,Hz and an image resolution exceeding one megapixel.


This paper describes a course of intellectual property rights which consists of knowledge acquisition subjects, design exercises for the creation of engineering devices, and design contests incorporating realistic constraints. Both design exercises and design contests are important for students to understand the objectives of intellectual property systems and the application of intellectual property rights. The design exercises with user' s requirements and several realistic constraints improve the design ability of the students. The design contests for the proposal and the conceptualization of engineering devices advance the student' s creativity.


Abstract: Australia's national arts curriculum has potential to realise the following benefits: cognitive, social, affective and curricular. This curriculum is designed for generalist and special arts teachers, but its delivery may be hindered by the prioritisation of high-stakes-tested disciplines and pedagogies, and reduced government funding to arts education across school and tertiary sectors. This may lead to a lack of opportunities to build teacher capacity in arts education, and diminished support for arts education in terms of time allocation and resourcing. The notion of 'silos', where the separation of teaching practices persists between teachers of different disciplines, discourages meaningful interdisciplinary collaboration and can promote less effective models of arts integration. Arts education embodies a range of intelligences and semiotic systems providing for inclusive curricula and educational equity. Arts Immersion is a proposed response to these factors, intended to be implemented through democratic generalist and arts specialist team-teaching in primary schools.


L e miqnē-ϕānīm is an undocumented phrase from Northwest Semitic, let alone a known collocation. Still, could it be plausibly read in the fifth line of an inscription on a silver plate from Tharros? The literal sense would be "in order to buy face", i.e., "to curry favour", "to acquire benevolence", "to become deserving of a positive attitude".


Ocean sailing yachts can, and do, capsize from time to time, and so the safety of those who sail on them is linked directly to their ability to self-right once capsized. Current regulations used for racing yachts are based on statical concepts, which have been shown to be inappropriate (Renilson et al 2000). In order to gain an understanding of the dynamic factors involved, experiments were conducted on a 1/12.5 scale model of an ocean sailing yacht in waves in the towing tank at the Australian Maritime College. Two different experimental procedures were developed: Testing in a single breaking wave, and testing in steep irregular waves. Four variations of the limit of positive stability were tested, together with one condition which had a different roll radius of gyration, without water on board the model. In addition, two variations of the limit of positive stability were tested to represent the condition with 4000 kg of water on board. From the tests it was possible to conclude that, for the given yacht, if the limit of positive stability is decreased from 119 deg to 104.7 deg the yacht is much less likely to self-right under the action of waves, with or without 4000 kg of water on board.