The interface is the bridge between new and old computer application systems. In the article, a new interface construction is developed. It is constructed that interface initiating subsystem, interface running subsystem and interface identify table. The new interface is simple, common and convenient.


This article explores how the members of Me and THE BAND, a rock band consisting of three ex-inmates and a music therapist, experienced playing together, how it helps them, and whether and how this can be related to the concept of self-help. Focus group interviews were conducted to explore the members' experiences, analysis was grounded in a hermeneutic philosophical understanding and the theoretical framework is based in a community music therapy approach. The study indicates how musicking helped the band members of Me and THE BAND'its to create agency, structure, meaning and community. The band appeared to function through collaborative processes, and the music therapists as facilitator need to prepare the qualities of equality, mutuality and participation. As a conclusion, the members of Me and THE BAND'its do not identify as being a self-help group, although they clearly report that musicking helps them. The crux of this paradox is that it is important for the group members to identify as a band, but they still include self-help concepts and traditions. They maintain their own uniqueness and independence, while making musicking a possible way out of criminality.


Treatment of clozapine-induced constipation was the most common indication for the medicines prescribed. Given how common this problem is and the risk of toxic megacolon, 2 this was not surprising. Gastric refl ux, secondary to gastric hypomotility, was also a common complaint. This was usually treated with a proton pump inhibitor, pantoprazole. Metabolic adverse effects (raised lipids, type 2 diabetes mellitus) were also a common reason for additional treatment. Although switching to another antipsychotic may alleviate the metabolic adverse effects of clozapine, 3 this is often not an option with treatment-resistant schizophrenia.


20 Co-amorphous mixtures have rarely been formulated as oral dosage forms, even though they have 21 been shown to stabilize amorphous drugs in the solid state and enhance the dissolution properties of 22 poorly soluble drugs. 23 In the present study we formulated tablets consisting of either spray dried co-amorphous ibuprofen24 arginine or indomethacin-arginine, mannitol or xylitol and polyvinylpyrrolidone K30 (PVP). 25 Experimental design was used for the selection of tablet compositions, and the effect of tablet 26 composition on tablet characteristics was modelled. Multimodal non-linear imaging, including 27 coherent anti-Stokes Raman scattering (CARS) and sum frequency/second harmonic generation 28 (SFG/SHG) microscopies, as well as scanning electron microscopy, X-ray diffractometry and 29 Fourier-transform infrared spectroscopy were utilized to characterize the tablets. 30 The tablets possessed sufficient strength, but modelling produced no clear evidence about the 31 compaction characteristics of co-amorphous salts. However, co-amorphous drug-arginine mixtures 32 resulted in enhanced dissolution behaviour, and the PVP in the tableting mixture stabilized the 33 supersaturation. The co-amorphous mixtures were physically stable during compaction, but the 34 excipient selection affected the long term stability of the ibuprofen-arginine mixture. CARS and 35 SFG/SHG proved feasible techniques in imaging the component distribution on the tablet surfaces, 36 but possibly due to the limited imaging area, recrystallization detected with x-ray diffraction was 37 not detected. 38


On modern multi-core, many-core, and heterogeneous architectures, floating-point computations may become non-deterministic and thus non-reproducible mainly due to non-associativity of floating-point operations. We introduce an algorithm to compute a product of two floating-point matrices that delivers reproducible results with the best possible accuracy. Our multi-level algorithm relies on fast vectorized floating-point expansions and as well as superaccumulators in a high-radix carry-save representation. We present implementations on recent Intel Xeon Phi accelerators and both AMD and NVIDIA GPUs.


Abstract The temperature variation of the refractive indices ( n o, n e) and density are reported for two liquid crystals. The order parameter is evaluated by both Vuks' and Neugebauer's approaches. The possible sources of error in evaluating the order parameter from refractive indices measurements have been discussed. The contradictory behavior of Δ n and Δχ during the nematic-smectic B phase transition of HBT has been explained on the basis of polydomain formation and the order parameter in the S B phase is estimated. The order parameter of two liquid crystals, HBT and OBT, is also evaluated by NMR measurements, confirming the polydomain formation in the S B phase of HBT.


13 Introduction Almost 3,000 lives were lost when, on September 11, 2001, 19 militants linked to the Islamic extremist group al-Qaeda hijacked four airplanes and used them to conduct suicide attacks against major targeted venues in the United States. The September 11, 2001, terrorist attacks prompted the US State Department to implement stricter border control, and a tightening of visa policies. These policies increased the magnitude of cross-border frictions for human travel into and out of the USA and significantly raised the bar for potential visitors of certain nationalities to obtain a short-term visa necessary for entering the United States. The impacts of these policies on the US economy were immense. For example, according to the National Foreign Trade Council, newly enforced border policies were responsible for US businesses making a staggering loss of $31 billion in sales, between the short period of 2002 to 2004. On the afternoon of March 11, 2011, life in eastern Japan was ravaged by the Great Kanto earthquake, the world's fifth largest earthquake over the course of the past century. As many as 15,000 lives were lost, and the tsunami which was initiated by the earthquake led to the melt-down of nuclear reactors in the Fukushima Daiichi Nuclear Power Plant. This series of disasters dealt a heavy blow to inbound tourism to Japan, especially in the immediate aftermath of the crisis. For example, an article entitled "Corporate travel to Japan dries up after quake", published by NBCNews.com, cites the chief executive of Partnership Travel Consulting, a Princeton, N.J.-based firm, in estimating that corporate travel to Japan had taken an 80 % plunge between the time of the earthquake and about slightly more than a week after. The earthquake also led to a massive exodus of foreign travelers from Japan, as travel companies and businesses with employees stationed in Japan endeavored to help them exit. Needless to say, the steep decline in foreign travel to Japan afflicted the nation's economic well-being tremendously. One only has to consider the value generated by foreign travelers in Japan which was estimated by the Japan Tourism Agency to be as much as ¥1.2 trillion in 2009—to grasp the severity of the situation. Moreover, the economic effect of spending by foreign tourists extends far beyond its face value, since tourist spending also exerts a ripple effect on production, a value-added inducing effect, and an employment inducing effect. Man-made and natural disasters, such as the above two crises, serve to elucidate how shocks to the tourism sector are intricately linked to the well-being of the economy, both at the national and global scale. Yet, despite the importance of tourism on economic welfare and policy-making, relatively little work has been dedicated to understanding the complex relationships between tourism and economic growth or development; tourism and trade; and tourism and economic geography. Further, perhaps due to limitations in the availability of statistical data, relatively little work has been conducted to understand the short and long-run effects of (positive and negative) demand shocks to the tourism sector. For example, although the literature on the use of natural experiments to establish causal effects or assess the impact of policies has been growing very rapidly within the field of economics, the literature has been relatively silent on the use of natural experiments to understand the tourism sector. The aim of this paper is two-fold. First, it seeks to explore how recent developments in the tourism industry may be analyzed through the lens of rigorous economic analysis. Second, it strives to inspire the reader by pointing to a myriad of possible topics for future research. In what follows, we shall explore some exciting research themes where the economist's toolbox has been used to analyze the tourism industry. These are, namely, tourism and trade; tourism and economic geography; and the use of natural experiments to establish causal effects or assess the impact of policies that have to do with tourism. Finally, we shall look at how the availability of statistical data on tourism in Japan has improved tremendously over the past decade or so. This is very inspiring, as the wealth of data that is currently available suggests that there is tremendous potential for future work to be conducted with regards to the links between tourism and economic activities.


A demonstration of the constant presence in uremic blood of an abnormal aromatic body such as indican would be highly significant since this would be suggestive of the nature of the abnormal metabolism. Hence a recent report 1 to the effect that indican is present in the blood in uremia invited confirmation, and especially as the amounts present are stated to be sufficient to give the ordinary blue color with chloroform when only 10 c.c. of serum are used for the test. Considering the total volume of blood this would mean an enormous concentration. The method for detecting indican employed by Obermayer, was, in brief, to separate all of the proteins from the serum by means of alcohol, which after filtration is evaporated on the steam bath. The residue from the alcohol filtrate is taken up in water, freed of salts with lead acetate and the latter in turn removed by sodium phosphate. A water clear filtrate is the final result which is tested by the usual method employed for urine with Obermayer's reagent. In repeating Obermayer's experiments the method above mentioned was used, also the separation of the proteins was conducted by means of phosphotungstic and hydrochloric acids and in a third series a method was used which is based on that of Rona for the precipitation of colloids in blood, by means of kaolin. The clinical material consisted of ten typical cases of uremia, all of the convulsive type. It was noted that indican could not be detected in fresh serum when 10 C.C. was used for tests; with larger amounts, 25 c.c., a questionable coloration of the chloroform resulted in one instance. If instead of using fresh serum or blood, the material be allowed to stand twenty-four to thirty-six hours many of the uremic bloods then gave a fairly definite reaction.


The ROLMIP (Robust LMI Parser) is a toolbox specialized in control theory for uncertain linear systems, built to work under MATLAB jointly with YALMIP, to ease the programming of sufficient Linear Matrix Inequality (LMI) conditions that, if feasible, assure the validity of parameter-dependent LMIs in the entire set of uncertainty considered. This article presents the new version of the ROLMIP toolbox, which was completely remodeled to provide a high-level user-friendly interface to cope with distinct uncertain domains (hypercube and multi-simplex) and to treat time-varying parameters in discrete- and continuous-time. By means of simple commands, the user is able to define polynomial matrices as well as to describe the desired parameter-dependent LMIs in an easy way, considerably reducing the programming time to end up with implementable LMI conditions. Therefore, ROLMIP helps the popularization of the state-of-the-art robust control methods for uncertain systems based on LMIs among graduate students, researchers, and engineers in control systems.


Cross-national research finds that "shadow education" — educational activities outside of formal schooling — tends to confer advantages on already privileged students. Shadow education in the United States, such as test prep for college entrance exams, has received considerably less attention. Drawing on the National Education Longitudinal Study, we analyze the likelihood of participation in, and the implications of, SAT preparation. Social class inequalities in test preparation, particularly costly SAT courses and private tutoring, are notable and have at least moderate consequences for SAT scores and selective college enrollment. We also find racial/ethnic variations in the use of test preparation. We consider the implications of these findings for understanding shadow education, stratification and educational mobility in the United States.


In 2012, the University of Illinois at Urbana-Champaign Library formed the International and Area Studies (IAS) Library as a part of the library-wide New Service Model (NSM) program's approach to librarianship (as described by Jacoby & Searing in Chapter 1) that emphasizes a deepened commitment to research services that aim to better coordinate and collaborate on patron-focused services. The NSM shift created, for the first time at Illinois, one library that combined the librarians, services, and collecting responsibilities representing African Studies; East Asian Studies; European Union Studies; Global Studies; Latin American and Caribbean Studies; Middle East and North African Studies; Slavic, East European, and Eurasian Studies; and South Asian Studies. Through the NSM merger, semiautonomous libraries, reading rooms, and units formed a singular IAS Library. One of the principle challenges of the consolidations was to ensure that the close working relationship among area studies faculty and the library could be maintained, if not enhanced, through a new model of service.


wound infections, fewer transfusions, and shorter incision length.1–3 In addition to these advantages, MIDCAB is a reasonable treatment option for proximal left anterior descending artery (LAD) stenosis, especially in patients who are not suitable candidates for percutaneous coronary intervention (PCI).4 M inimally invasive direct coronary artery bypass (MIDCAB) is a method of coronary artery bypass graft (CABG) surgery that is performed without a median sternotomy. It has similar clinical outcomes but many advantages over conventional CABG, including shorter intensive care unit (ICU) stay, fewer


Objective:To extract and determine the Fatty Acid in the Trachyspermum Ammi(L.).Method:The chemical components of the two parts were studied by GC-MS.Result:Four kinds of acid from the Trachyspermum Ammi(L.)were identified including linoleic acid,oleic acid,stearic acid,palmitic acid.The linoleic acid and oleic acid were main components among them.Conclusion:This method is simple,fast and accurate.


A closed loop supply chain with one manufacturer and one retailer is considered in fuzzy environment, the manufacturer is in charge of collecting the used product. The manufacturer produces a new product directly from raw materials or from collected products and wholesales it to the retailer who then sells it to the end consumer. The optimal wholesale price, optimal retail price and optimal collecting rate are given under centralized and decentralized decision cases.


In contrast to the conventional bulky and high -frequency active power filters (APFs), a novel APF is proposed and its control strategy is optimized. Compared with the typical single- phase APFs, the proposed APF uses less switches, low capacity capacitor and no energy- storage component in DC- side, featuring simple structure, small volume and high efficiency. Using switching time as variable parameters, the precise mathematic model of compensated current in APF is obtained by analyzing the main circuit. Genetic algorithm (GA) is employed to optimize the switching instants in main circuit to minimize total harmonic distortion (THD) in the power system as well as decrease operating frequency of APF greatly. The single- phase system model with rectifier load is built through simulating the integrated Matlab/Simulink software, and simulation results confirm the correctness and effectiveness of the proposed APF.


Setcor is an advanced statistical module which should be of great interest to social scientists. It requires ownership of Systat. While its command-driven user interface is more challenging than some menu-driven approaches, the package is relatively easy to use. The documentation and examples are bare-bones and do not suffice for instructional purposes. For those familiar with the concepts and purposes of set correlation—to implement a set analog to multiple linear regression— this module will be a welcome research tool.


This article examines perceived change in communication and closeness between adolescents and parents after four weeks in adolescent residential chemical dependency treatment. Adolescents completed perception of parent-adolescent communication, closeness, and open-ended questionnaires before (n = 18) and after (n = 10) treatment and perceived changes in relationships after treatment. T-tests compared (a) those completing the post-test with those not, (b) pre- and post-test responses, and (c) pre- and post-test responses based on parents' attendance at multi-family therapy groups (MFTG). Positive change occurred after four weeks, especially when parents attended MFTG. The critical role of parent involvement in adolescent treatment needs recognition by funding and referral sources.


We have surveyed the commercial resist market with the dual purpose of identifying diazoquinone/novolac based resists that have potential for use as e-beam mask making resists and baselining these resists for comparison against future mask making resist candidates. For completeness, this survey would require that each resist be compared with an optimized developer and development process. To accomplish this task in an acceptable time period, e-beam lithography modeling was employed to quickly identify the resist and developer combinations that lead to superior resist performance. We describe the verification of a method to quickly screen commercial i-line resists with different developers, by determining modeling parameters for i-line resists from e-beam exposures, modeling the resist performance, and comparing predicted performance versus actual performance. We determined the lithographic performance of several DNQ/novolac resists whose modeled performance suggests that sensitivities of less than 40 (mu) C/cm2 coupled with less than 10-nm CD change per percent change in dose are possible for target 600-nm features. This was accomplished by performing a series of statistically designed experiments on the leading resists candidates to optimize processing variables, followed by comparing experimentally determined resist sensitivities, latitudes, and profiles of the DNQ/novolac resists a their optimized process.


Applied researchers often use tests based on contingency tables, especially in preliminary data analysis and diagnostic testing. We show that many such tests may be alternatively implemented by testing for coefficient restrictions in linear regression systems.


While a student at the University of Cambridge, beginning in 1902, Adrian Stephen became a friend of Horace de Veré Cole, a wealthy and often outrageous jokester, assumed to be the mastermind behind two famous pranks. The first ruse in 1905 exposed the provincialism of Cambridge's municipal officials, as they were duped into giving a tour of Cambridge to a supposed entourage of the Sultan of Zanzibar. The second prank in 1910 exposed the vulnerability and naivete of the British Navy, as the officers of the H.M.S. Dreadnought were duped into giving a tour of their flag ship to the supposed court of the Emperor of Abyssinia. The Zanzibarian and Abyssinian entourages both included Horace Cole and Adrian Stephen. The second also included Duncan Grant and Virginia Stephen. Both escapades were improbably and outrageously successful. The second has fascinated readers for nearly ninety years, and feminists in particular have read the frequently reproduced photograph of Virginia Stephen—later Woolf—in black face and a beard as a harbinger of later assaults on the patriarchy.1 But Virginia's iconoclasm long antedated the 1910 hoax, as did her brother Adrian's. Unpublished family documents in fact suggest that, emboldened by Virginia's example and Stephen family habits of rivalry and mockery, Adrian, rather than Horace Cole, conceived of the 1905 hoax. The exposition for this drama dates from the childhood of the Stephen siblings: Vanessa (b. 1879), Thoby (b. 1880), Virginia (b. 1882), and Adrian (b. 1883). From the age of nine, Virginia,


The periodic signals used in electronic circuits (e.g. as timings) are a major cause of interference which can be reduced by introducing suitable modulations. Chaotic sources have so far been proposed for producing the modulating signals only as cheap replacements for random generators. Focusing on fast modulations it is shown that chaotic signals can also outperform random ones.


Clinicians frequently equate symptoms of volume overload to heart failure (HF) but such generalization may preclude diagnostic or etiologic precision essential to optimizing outcomes. HF itself must be specified as the disparate types of cardiac pathology have been traditionally surmised by examination of left ventricular (LV) ejection fraction (EF) as either HF with preserved LVEF (HFpEF-LVEF >50%) or reduced LVEF of (HFrEF-LVEF <40%). More recent data support a third, potentially transitional HF subtype, but therapy, assessment, and prognosis have been historically dictated within the corresponding LV metrics determined by echocardiography. The present effort asks whether this historically dominant role of echocardiography is now shifting slightly, becoming instead a shared if not complimentary test. Will there be a gradual increasing profile for cardiac magnetic resonance as the attempt to further refine our understanding, diagnostic accuracy, and outcomes for HFpEF is attempted?


Summary Fine grained waste zeolite in the form of a zeolite dust or a finely ground zeolite can be used as an active pozzolanic admixture to lime mortars. Lime mortars containing various content of fine grained zeolite were prepared and tested. Development of compressive strength, shrinkage and weight loss of lime mortars stored in different conditions was then evaluated. X ray powder diffraction of lime-zeolite pastes was also used to evaluate lime-pozzolan reaction. The results confirmed that fine grained zeolite can be usefully used as pozzolanic addition to lime mortars. Positive effect of pozzolan on the compressive strength of mortars is effective when mortars are stored in humid atmosphere where favorable conditions for lime-pozzolan reaction are. However, compressive strength of mortars stored in open air at RH 65% cannot fully develop and after some time it even decreases.


Taking advantage of direct integration of state equation method for dynamic response of structure which is put forward by Senwen Zhang etc., it can analysis of the structure of reinforced and unreinforced dynamic response. Doing this, it can solve the complex problem of difficult calculation of the damping force. What's more, the result of enhancing the stability of structural can be achieved.


The friction Stir Welding is a process involving plastic deformation of the materials to be joined. This process does not involve the melting of the materials to be joined. This thing makes this process suitable for joining the different materials having different mechanical and chemical properties and different material structure. This review mainly providesfeasibility about the suitability of the FSW technique to join the various different materials/alloys.


Hereinafter we report an onion-liked carbon (OLC) and a fullerene-liked carbon (FLC) materials synthesized via TNT & RDX detonation technique and acetylene gas explosion process respectively. Abundant micropores, mesoporous, as well as different spatial structures exist inside the two carbon materials. They demonstrate a good conductivity and sulfur storage capacity, and various rich pore structure inhibiting the shuttle effect of the solved lithium polysulfide in the charge-discharge process. The pore size distribution, pore volume, specific surface area, electronic conductivity, composite structure, interaction between sulfur and carbon, and cell performance are researched. The Li-S battery furnished with the two carbon-sulfur hybrid materials as the cathode host material delivers a well reversible rate cycling performance, and a low decay rate of 0.037% and 0.056% per cycle during 1000 cycles at 1C for FLC and OLC respectively with a sulfur load of about 2.2 mg/cm2. The excellent electrochemical perfor...


The group came together in the late 1990s to organise a series of cross-border drama workshops.
Sector: Education
Address: UCD Drama Studies Centre, Carysfort Avenue, Blackrock, Dublin, Ireland
Phone: +353 (0)1 716 8049
Email: email@example.com


The distribution power system in ship is very similar to a microgrid and supplies energy to navigation and operation system as well as sophisticated systems of weapons and communications. After a fault is encountered, reconfiguration refers to changing the topology of the microgrid distribution network in order to isolate system damage and/or optimize certain characteristics of the system. Reconfiguration problem in microgrid is nonlinear with numerous discrete variables and additional constraints. Traditional optimization methods are not the best solution due to tendency of getting stuck to a suboptimal solution. In this work, intelligent methods such as genetic algorithm (GA) and particle swarm optimization (PSO) have been applied for microgrid reconfiguration with shipboard power system (SPS) as an example. Proposed methods are capable to satisfy the operational constraints and consider load priorities. Graph theory is utilized to represent the microgrid network topology. Proposed intelligent reconfiguration algorithms were implemented using MATLAB and tested on 8-BUS and 13-BUS SPS models including distributed generations (DGs) and islands. Test systems were reconfigured in three different possible scenarios by considering load priority, load magnitude, and by combining these two simultaneously. Developed reconfiguration algorithm was also implemented in real time using controller-in-the-loop with real time digital simulator. Simulation results show satisfactory performance for several test case operating scenarios.


A sample of 189 depressed patients, previously studied in detail, was followed up 10 months after initial treatment contact. Thirteen of these individuals had made suicide attempts, one fatally, during the period. Sociodemographic variables, previous history, personality dimensions, and symptom ratings were analyzed in order to explore predictors of suicide attempts. Persons who made suicide attempts during the follow-up period were significantly differentiated from the nonattempters by a number of variables. Attempters were younger, had a previous history of suicide attempts, evidence of underlying personality disturbance suggestive of character disorder, and a clinical pattern of neurotic rather than endogenous depression. They showed striking evidence of persistent overt hostility. These findings are consistent with other descriptions of groups of suicide attempters among general populations. Because their hostility may lead them to drop out of treatment, attention to follow-up care after the resolution of the immediate depressive episode is especially important for such patients.


Department of Psychology, University of California, San Diego, USASummary: It is often said that contemporary students frequently study while 'multitasking'. However, this rather diffuse termencompasses situations that vary as to the whether the learner controls the pace at which educational materials are provided.On the basis of prior cognitive research, we hypothesize that this may well be a critical determinant of interference. Three studiesrequired students to read or listen to several short historical narratives and also to engage in five to eight very short conversations(akin to an instant messaging conversation). In Experiment 1, subjects read the narratives; here, multitasking marginallyincreased total time spent reading the narratives, especially when it occurred at random times. However, final memory for thenarratives was not significantly affected. Similar results were obtained when the narratives were presented in audio format andthe learner could pause them while conversing (Experiment 2). By contrast, when audio narratives did not pause, interruptionsreduced comprehension performance (Experiment 3). Copyright © 2013 John Wiley & Sons, Ltd.Supporting information may be found in the online version of this article.


THOUGH RELIABLE evidence is not available, one gets the impression that, in recent years, the use of one or more "group techniques" in teacher education classes has increased markedly. For ex ample, one instructor in a nationally known gradu ate college of education estimated that the use of buzz groups or discussion groups in course work in that institution had increased by approximately 60 percent in the space of about five years. Indeed, one is hard put to encounter students on either a graduate or undergraduate level who have not had rather wide experience in the classroom use of groups or group techniques, varying from large class discussion to buzz groups, project groups, role playing, panels, etc. Such an apparent widespread increase in the use of group teaching methods prompts one to assume that weighty evidence is at hand to suggest that " groups are good. " An examination of the research, however, reveals that this is not necessarily the case at all. What we are confronted with is a situ ation of conflicting, inconclusive research results. Bovard has summarized the problem in the follow ing way:


The present study examines the relation between classroom climate in schools for secondary special education and students' perceived social exclusion. A total of 401 Dutch adolescents (70.3% males) with conduct problems, attending schools for special education, filled out questionnaires on classroom climate, problems in social information processing, externalizing behavior and perceived social exclusion. Results showed that a positive classroom climate was associated with a reduction of students' externalizing behavior problems and perceived social exclusion, which was associated with improvements in social information processing. However, these relations were only found at the within group level of analysis (between students) and not at the between group level (between classes); thus contextual (class level) effects could not be demonstrated. It can be carefully stated that a positive classroom climate in secondary special education may protect against perceived social exclusion. Future research is required to examine whether our findings can be replicated in other schools for secondary special education or can be generalized to secondary education in general.


fading behaviour hardly depends on the rnelting of reactions with oxygen, sulphur. 20〜30%of consumption. covering of magnesium−treated cast irons with MgO decreases the fading rate of magnesium a little, while the covering with BaF2, CaF2 and MgF2 increases it considerably in the order. (4) It has been clarified that these results are satisfactorily explained if the escape of magnesium from the melt is mainly due to the floating−up of magnesium gas bubbles.


Objective To evaluate the effects of occupational therapy and Taoist cognitive psychotherapy on emotional disorder of stroke patients.Methods A total of 136 hemiplegic patients with emotional disorder were randomly divided into a general treatment group,a cognitive psychotherapy group,an occupational therapy group and a combined therapy group(occupational therapy combined Taoist cognitive psychotherapy group).All patients were treated accordingly for 8 weeks and followed up for 6 months.All the patients were evaluated with Fugl-Meyer Assess- ment,COPM and SCL-90.Results It was found that the Fugl-Meyer Assessment and COPM scores were improved gradually in all groups.The combined therapy group scored higher than occupational therapy group(P0.01),the occupational therapy group scored significantly higher than general treatment group and cognitive psychotherapy group (P0.01).The SCL-90 scores(100.36±26.41,53.89±12.45,63.65±16.23)in the occupational therapy group were lower than general treatment group(98.22±25.38,62.72±13.90,80.36±21.79;P0.01).The SCL-90 scores(99.18±24.56,58.63±12.27,44.72±10.54)in cognitive psychotherapy group were signifieantly lower than occupational therapy group in the end of the follow-up period(P0.01).The SCL-90 scores(100.42±25.44,49.15±11.84,39.26±10.47)in combined therapy group were lower than those in cognitive psychotherapy group and occupational therapy group(P0.01).Conclusion The occupational therapy or Taoist cognitive psy- chotherapy can help improve emotional disorder in patients with hemiplegia,and improve their motor function of upper limbs and activities of daily living performance.Occupational therapy in conjunct with Taoist cognitive psychotherapy may significantly help improve stroke patients both physically and mentally.


The State as the legal and political organization known more perfect than at
present. Unit is an organic entity, legally structured in the form of a corporation,
responsible for the exercise of power, in order to further the common good.
This has required a set of legal rules governing the organization, functions and
power of public administration in its dealings with individuals and the relationship
between the bodies that comprise it, to this systematic set of principles and rules
called the Administrative Law.
In order to comply with the purposes of state and social needs that are oriented
toward the common good, it develops a wide range of events, acts and
proceedings in the work of public administration, so those manifestations of the
actions public are reflected in the implementation of the Organic Law on National
Public Procurement System.
Considering that public procurement leads to the meeting point between the public
and private, we realize that economic interests are very large so it is necessary to
ensure transparency in these processes discarding the possibility of exercising
corrupt practices, with the prevalence descrecional the power of a contracting
entity.
With the National Public Procurement System is intended to achieve the use of
public procurement to stimulate domestic production, encouraging the participation
of medium, small and micro enterprises in Ecuador, suggesting an agile without
forgetting transparent, fair, democratic and technicians, all allow participation on
equal terms to all bidders, then it is necessary to fully comply with the principles
governing public procurement.


An experiment was conducted during 2004-05 to study the petiole nutrient norms using diagnosis and recommendation integrated system from 60 papaya (Carica papaya) gardens. A total of 300 samples were collected (sixth petiole from apex) to analyze for macro and micronutrients for establishment of the data bank. The whole population was divided into 2 sub-groups, namely low and high yielding by using diagnosis and recommendation integrated system and thus selected 45 nutrient expressions as diagnostic norms. These expressions had shown higher variance and lower coefficient of variation that are found to have greater diagnostic precision, viz N/P (6.368), N/K (0.571), Mg/N (0.899), N/Zn (0.045), Ca/Mn (0.062), Ca/Zn (0.115), Mg/Zn (0.039) and S/Zn (0.010) etc. The nutritional balance index indicates the overall imbalance of the nutrient-based on sum of the indices irrespective of sign. The diagnosis of nutrient imbalance through diagnosis and recommendation integrated system indices indicated that the most common yield-limiting nutrient is zinc, followed by potassium. In addition, 5 nutrient ranges have been derived using mean and standard deviation as low, deficient, optimum, high and excess for each nutrient to serve as a guide for diagnostic purpose. The optimum N ranged from 0.91 to 1.44%, P from 0.12 to 0.28%, K from 2.22 to 3.75%, Ca from 2.65 to 4.19%, Mg from 0.67 to 1.37% and S from 0.18 to 0.37%. Among the micronutrients the optimum Zn ranged from 17 to 40 ppm, Fe from 33 to 92 ppm, Mn from 34 to 60 ppm and Cu from 6 to 12 ppm for papaya.


A new thin-layer chromatography method was developed to detect parathion-methyl (0.0-dimethyl-0-p-nitrophenyl phosphorothioate) and its metabolite methyl-paraoxon and the degradation produce p-nitrophenol in samples of animal and plant origin. Coupling with Bratton-Marshall reagent, as used in colorimetry, was employed to detect the compounds on the chromatography plate. Pretreatment of the samples was simplified by preparing a crude extract and separating unwanted substances from the pesticide compounds by thin-layer chromatography.


Background Free functional gracilis transfer (FFGT) is one of the most important methods for the treatment of total brachial plexus avulsion. However, postoperative adhesion and fibrosis of the transferred muscle compromise the effectiveness. This study is to investigate whether intact epimysium and FTY720 could reduce adhesion and fibrosis following FFGT in rabbits.Methods A total of 60 New Zealand White rabbits were randomly divided into 4 groups: Group 1 was set as control, and orthotopic gracilis transfer models were established in Group 2-4, with different interventions: epimysium resection (Group 2), epimysium preservation (Group 3) and epimysium preservation combined with FTY720 treatment (Group 4). After that, at each time points (1, 3, 7, 14, and 56 days postoperatively), three rabbits in each group were selected to harvest their gracilis and adjacent muscles for histological analysis including hematoxylin & eosin (HE) staining, Masson staining, and anti-transforming growth factor beta 1 (TGF-β1) immuno-histochemical staining. Additionally, the thickness of extragracilis adhesion band by ultrasonography were also assessed at days 56.Results All of HE, Masson and TGF-β1 stains confirmed that there were least inflammatory cell infiltration, adhesion and fibrosis of the transferred gracilis in Group 4 than those in Groups 2 and 3. At the 56 days postoperatively, the thickness of the adhesion band of gracilis was lightest in group 4 than that in Groups 2 and 3. Conclusions For the functional gracilis transfer, epimysium preservation and FTY720 could relieve the inflammatory response between gracilis and adjacent muscles, reduce the fibrosis and adhesion.


Sentiment classification is a popular text mining task in which textual content (e.g., a message) is assigned a polarity label (typically positive or negative) reflecting the sentiment expressed in it. Sentiment classification is used widely in applications like customer feedback analysis where robustness and correctness of results are critical. In this article, we highlight that prediction accuracy alone is not sufficient for assessing the performance of a sentiment classifier; it is also important that the classifier is not biased toward positive or negative polarity, thus distorting the distribution of positive and negative messages in the predictions. We propose a measure, called Polarity Bias Rate, for quantifying this bias in a sentiment classifier. Second, we present two methods for removing this bias in the predictions of unsupervised and supervised sentiment classifiers. Our first method, called Bias-Aware Thresholding (BAT), shifts the decision boundary to control the bias in the predictions. Motivated from cost-sensitive learning, BAT is easily applicable to both lexicon-based unsupervised and supervised classifiers. Our second method, called Balanced Logistic Regression (BLR) introduces a bias-remover constraint into the standard logistic regression model. BLR is an automatic bias-free supervised sentiment classifier. We evaluate our methods extensively on seven real-world datasets. The experiments involve two lexicon-based and two supervised sentiment classifiers and include evaluation on multiple train-test data sizes. The results show that bias is controlled effectively in predictions. Furthermore, prediction accuracy is also increased in many cases, thus enhancing the robustness of sentiment classification.


November 24, 2015 ~ JSGS Public Lecture ~ "Small Modular Reactors: Energy Opportunities and Regulatory Views" Presented by Neil Alexander, Executive Director, Sylvia Fedoruik Canadian Centre for nuclear Innovation, Marcel de Vos, Senior Project Officer, Regulatory Operations Branch, Canadian Nuclear Safety Commission, Kevin Lee, Senior Regulatory Policy Officer, Regulatory Affairs Branch, Canadian Nuclear Safety Commission. Moderated by Dr. Jeremy Rayner, JSGS.


Objectives: The aim of the present study was to evaluate the associations of parental bonding and adolescents' Internet addiction symptoms with depression and anxiety in parents of adolescents with attention deficit/hyperactivity disorder (ADHD). Methods: Parental depression and anxiety symptoms, parental bonding, and adolescents' Internet addiction symptoms were assessed in 46 parent-child dyads using the Center for Epidemiological Studies Depression Scale, State-Trait Anxiety Inventory, Parental Bonding Instrument (PBI), and Chen Internet Addiction Scale, respectively. Forward stepwise multiple regression analysis was used to examine the associations of parental bonding and adolescents' Internet addiction symptoms with parental depression and anxiety. Results: Low care/affection on the PBI was significantly associated with parental depression, and overprotection on the PBI and adolescents' Internet addiction were significantly associated with parental anxiety. Discussion: Parental bonding and adolescents' Internet addiction are related to depression and anxiety in parents of adolescents with ADHD. Wong CK et al. / Arch Clin Psychiatry. 2019;46(2):40-3


The growing industrial attention toward rapid methods and the wide use of nucleic acid amplification techniques has led for developing and applying of PCR based methods for food-borne pathogens recognition. In the current study, 20 cheese samples, collected from a local supermarket of Jeddah, Saudi Arabia were examined for the presence of metals and some pathogenic bacteria. Cheese content of Na + and K + were found to be higher in fresh cheese than other elements. Cr 2+ , Ni 2+ , Zn 2+ and Al 3+ were detected at low concentrations in cheese. Additionally a multiplex PCR method was developed for detection of Salmonella spp., Listeria monocytogenes and Escherichia coli O157:H7 as the most common cheese borne pathogens. Bacterial enrichment was carried out and bacterial genomic DNA was extracted. A set of primers was designed based on specific genes for Salmonella spp. (invA), L. monocytogenes (prfA) and E. coli O157:H7(eaeA). Additionally, a universal –multiplex PCR based on the highly conserved sequences published on genbank database for the previous genes was used for detecting the previous cheese borne pathogenic bacteria. Three (15 %) out of 20 cheese samples, were contaminated with pathogenic bacteria. Finally, the used method is a promised method, simple, rapid and efficient for detecting pathogenic bacteria in contaminating cheese.


In this paper, we study joint link scheduling and power control with successive interference cancellation (SIC), aiming at maximizing the α-utility. The joint link scheduling and power control with SIC (PCSIC) problem is formulated to be a mixed-integer non-linear programming (MINLP), which is NP-hard. In order to solve the problem, we first decompose the MINLP into three sub-problem and then propose an iterative algorithm. We compare our strategy with the scheme without power control from the perspective of system throughput, fairness index and energy consumption. Numerical results show the noticeable performance improvement of the proposed strategy.


This paper evaluates the effectiveness of three nonlinear static methods for the prediction of the dynamic response of in-plan irregular buildings. The methods considered are the method suggested in Eurocode 8, a method previously proposed by some of the authors and based on corrective eccentricities and a new method in which two pushover analyses are considered, one with lateral forces applied to the centres of mass of the floors and the other with only translational response. The numerical analyses are carried out on a set of refined models of reinforced concrete framed buildings. The response predicted by the nonlinear static analyses is compared to that provided by nonlinear dynamic analyses. The effectiveness of the nonlinear static methods is evaluated in terms of absolute and interstorey displacements.


Abstracts: The approved IEEE standard 1596-- The Scalable Coherent Interface (SCI) --makes it possible to couple up to 64K nodes together. In order to connect thousands of nodes toconstruct large scale SCI-based processing systems, one has to interconnect these nodes byswitch elements to form different topologies. A summary of the requirements and key points ofinterconnection networks and switches is presented. Two models of the SCI switch elements areproposed, 1) an SCI-bridge and 2) an SCI-switch. An SCI-bridge is in principle two SCI nodechips connected back to back. An SCI-switch provides a direct connection between any tworinglets that are connected to the switch. Such an SCI-switch will significantly improve systemperformance and give a lower latency. Furthermore it shows good scalability. We investigateseveral examples of systems constructed from 4-switches with simulations and the results areanalyzed. Some issues and enhancements are discussed to provide the ideas behind the switchdesign that can improve performance and reduce latency. The possibility of implementing anSCI-switch in a multi-chip module is investigated. The goal of this paper is to study some of thedesign criteria for the switch elements to form the interconnection of large scale SCI-basedprocessing systems.Keywords: SCI switch element, SCI-bridge, SCI-switch, topologies, management of large SCIsystems, reliability, latency, performance, multi-chip module.


The surface ship command system (SSCS) for the Royal Navy Type 23 Frigate and the Auxiliary Oiler Replenisher (AOR) self-defending logistics vessels is being designed and produced by Dowty-SEMA Ltd. Three constituent companies act as sub-contractors to the consortium in producing parts of the system. The contractual interface between Dowty-SEMA and the sub-contractors at a technical level takes the form of specifications which define the requirements for the subsystems being designed. At an early stage in the system definition, it was decided within Dowty-SEMA that an automated system for tracing the very large number of system requirements from the MoD requirements down to the specifications was essential. Shortly afterwards, RRDS decided to design tools to extend this traceability scheme down from the specifications through the entire software development lifecycle. The paper discusses the purpose of a requirements traceability system, embedded machine readable traceability keyphrases, keyphrase syntax, the Dowty-SEMA traceability scheme, and the RRDS traceability scheme.


Colorado's recent experience with energy development on state land provides a useful example of the "all of the above" energy ethic. Most of this development has involved unconventional oil and gas formations, but it has also included coal and a range of renewable energy resources. This development has generated hundreds of millions of dollars for public schools and other public institutions. But perhaps more important, it has illustrated how energy development may be combined with environmental conservation. To achieve these conservation goals, the State Land Board has employed a number of innovative measures, including collaborative planning, special leasing procedures, updated lease forms, and environmental stipulations. These measures should be of interest to the many other states whose trust lands are or may be subject to energy development.


We have investigated by NMR the structure and dynamics of cobalt and nickel complexes of pyridlle in water solutions. At high temperatures, fast exchange prevails and the geometry of the complexes can be derived from the spin-lattice relaxation times. At low temperatures, slow exchange obtains and the contact and dipolar shifts may be found from the spectrum of bound pyridine. In the intermediate range, tire exchange kinetics may be studied. We find a value of ca. 3A for the metal pyridine distance, an average number of 3.5 bound molecules in the complex, and activation energies for chemical exchange of 16 k&/mole for nickel and 22 kcal/mole for cobalt. The l&and molecules undergo free rotation about the metal nitrogen bond.


A new curing system used for prolonging the shelf-life of epoxy resin-based microelectronic packaging material (E-MPM) was first prepared by an in situ tubing/entrapping method. Based on supramolecular interactions a curing accelerator (C) for epoxy resin, boron trifluoride–pyridine (BF3·Py), has been trapped into the pores of polyorganosiloxane (POS) containing a nanoscale tubular structure, which is prepared by hydrosilylation of two reactive, cis-isotactic ladderlike polyallylsilsesquioxane (Allyl-T) molecules with two reactive, α,ω-coupling agents (1,1,3,3-tetramethyldisiloxane, H-MM) in two plus two (2 + 2) mode using Cp2PtCl2 as catalyst. Various characterizations including optical polarized microscopy (OPM) observations, differential scanning calorimetry (DSC) measurements, storage
and curing tests and molecular mechanical simulation are combined to confirm that the accelerator BF3·Py is simultaneously trapped during the formation of POS and moreover, to indicate that entrapment of the accelerator C with POS is a promising alternative way to prolong the shelf-life of the E-MPM at ambient temperature.


In this paper, we first study infinitesimal deformations of a Lie conformal algebra and a Lie conformal algebra with a module (called an [Formula: see text] pair), which lead to the notions of the Nijenhuis operator on the Lie conformal algebra and the Nijenhuis structure on the [Formula: see text] pair, respectively. Then, by adding compatibility conditions between Nijenhuis structures and [Formula: see text]-operators, we introduce the notion of an [Formula: see text]-structure on an [Formula: see text] pair and show that an [Formula: see text]-structure gives rise to a hierarchy of pairwise compatible [Formula: see text]-operators. In particular, we show that compatible [Formula: see text]-operators on a Lie conformal algebra can be characterized by Nijenhuis operators on Lie conformal algebras. Finally, we introduce the notions of the conformal r-matrix-Nijenhuis structure and symplectic-Nijenhuis structure on Lie conformal algebras and study their relations.


The march of the digital frontline seems to have relentlessly vaporised so much of what is around us and sent it to the cloud. With our heads now so often stuck in those clouds we seem to be losing touch of what is physically around us; including each other. What if we could add a digital soul to everyday objects and design, prototype and manufacture physical products almost as quickly as digital experiences? My work is a journey towards attempting to let some of this happen.


Guelzo, Allen C. Fateful Lightening, A New History of the Civil War and Reconstruction. New York: Oxford University Press, 2012. x + 576 pages. Paper, $19.95. Allen Guelzo's Fateful Lightening is a wonderful book. It is the summit of a long career of a consummate historian. It is much more in-depth history than such popular histories as James McPherson's 1988 work, Battle Cry of Freedom. Yet Guelzo's prose is so effortless that it reads as well as similar popular histories of the era. It is a timely addition to a long tradition of scholarly histories of both the Civil War and Reconstruction. The most recent comprehensive work, that of historian Shelby Foote, is getting a bit dated, so it is time for another addition to this tradition of excellence in scholarly historiography. Guelzo's coverage of the war itself and the various battles and campaigns is more than adequate, but I found other sections of Fateful Lightening even more interesting. Guelzo seamlessly weaves the history of actual warfare with other cultural and historical events of the time. He offers, for example, a masterful introduction to the history of the Republic before 1860 and an insightful review of the historical, cultural, and social factors that led inevitably to the war. It was not a forgone conclusion that the two regions would go to war against each other, he argues, but the vast historical, cultural, social, and political differences between the two regions provided almost inevitable clashes about western expansion, slavery, and tariffs. Guelzo also points out that it was not a settled issue that states could not secede from the union as the several real threats of groups of states to secede leading up to actual secession prove. The discussion of the rational or irrational sources of the war is particularly good. It was, writes Guelzo, a perfectly rational choice to secede and go to war--as against many other historians that claim that the conflict resulted from an irrational set of decisions. Given the historical, cultural, and social differences regionally, as well as the history leading up to secession, secession and war seemed entirely rational and logical decisions. Guelzo's analysis of Abraham Lincoln, spread out throughout the book, is some of his best work in this text. Being the author of a book-length work on Lincoln, Guelzo has an almost intuitive grasp of the quirks of Lincoln's personality as well as his political savvy, and his evolving thinking about race, slavery, and abolition. He comes across as a complex man who retained a driven ambition despite a string of failures, which were later capped by one great success in his election as president. Lincoln's thinking about race, slavery, and abolition evolved over time and Guelzo is most astute in his charting of this evolution. …


An H.264-based fast 3-D video compression algorithm is pre- sented by reducing coding complexity of P slices in a depth map sequence using a fast-mode decision scheme. On the basis of the relationship of coding modes of collocated macroblocks on texture and depth frames, an early SKIP-mode decision scheme and a selective prediction-mode decision scheme have been developed to rapidly encode depth map se- quences. Experimental results show that the algorithm can save the entire encoding time by 79% on average compared to conventional a depth map sequence coding algorithm, while introducing only negligible loss in peak signal-to-noise ratio value. C 2011 Society of Photo-Optical Instrumentation Engineers


The fungi from the Trichophyton mentagrophytes / T. interdigitale species complex are the prevalent causative agents of skin and hair disease in humans and other mammals. Here we review lines of evidence supporting the recognition of three independent species within the complex in the light of more recent contradicting data and conclude that none of them are satisfactory. While ITS region genotyping appears to be more reasonable when compared to species identification, the knowledge on epidemiological sources, regional distribution and antifungal drug resistance of T. mentagrophytes / T. interdigitale genetic lineages is still incomplete.


Purpose - The purpose of this paper is to examine the intention of companies to reduce transportation emissions by 2020 and the barriers and the discriminating factors that affect the reduction. De ...


End-of-life care is an area of continuing development in light of new technologies that allow doctors to extend life beyond what was previously possible. With this ability come concerns over when it is appropriate to engage such life support measures. Unfortunately, there exists no universal guideline to end-of-life decision-making, and factors such as culture and religion further confound matters. Here we show that physician religious affiliation does indeed influence decision-making and we extrapolate this concept to the Shiite Muslim preponderance of physicians in Iran. We also demonstrate the need for reconciliation between medicine and religion in Iran so that patient care during the end of life can be improved.


This introductory chapter provides an overview of the issues that the book discusses, as well as the challenges in editing it. The book offers diverse critical perspectives, both international and cross-disciplinary, on the challenge of how to make sense of contemporary forms of populism and also how community development responds to these. It particularly focuses on right-wing populism. How can those committed to community development endeavours respond to populism? When thinking about any community development response to populism, it is important to understand that feelings of alienation and resentment, and concerns about uncertainty and material insecurity, have a rational basis. From this perspective, populism should be viewed as a symptom of underlying factors that have characterised much of the global state of affairs since the last decades of the twentieth century. Taking the viewpoint that populism is a symptom, any response to populism must be cognisant of the underlying conditions in which populism has arisen. The chapter then considers the view that populism is a symptom of the deterioration of the project of democracy.


Korea has adopted a federal renewable electricity standard that begins at 2% in 2012 and requires companies to source 10% of their electricity from renewables by 2022. Therefore the interest in the use of biomass as a renewable energy resource is growing. By importing biomass, the Korea, which produces too little biomass of its own, can meet the needs of the renewable energy sectors. In the case of import biomass, it will cost a great deal on the transportation and logistics of biomass materials. Therefore new research and development on the biomass fuel with high energy density is needed to reduce logistics cost on transportation of the biomass fuel. Torrefaction is a thermochemical treatment process of biomass at temperatures ranging between 200 and 300oC. Typically, 70% of the mass is retained as a char product, containing 90% of the initial energy content. Torrefaction experiments on samples of EFB were performed in a fixed bed reactor to determine the effect of operation variables such as reaction temperature (205-310oC), reaction time (20-40 min) and air ratio (0-0.18) on char yield and characteristics. Increase of the torrefaction temperature led to a decrease of the yield of the char. The heating value of char increased with the increase of the reaction temperature, because the carbon content increased and hydrogen and oxygen content decreased. The yield of char decreased with increasing air ratio. This suggested that oxidation of EFB occurred during torrefaction in the presence of oxygen.


The exact solution for plane wave propagation through periodically alternating solid and fluid layers has been derived for all frequencies and all wave numbers. In the low‐frequency limit an explicit dispersion relation is found relating the wave slowness parallel to the layering to that perpendicular to the layering. At any angle of propagation, except perpendicular, there are two waves: a fast wave and a slow wave. The tangential motion across a solid fluid interface for the fast wave is in phase, and for the slow wave, out of phase. An equivalent medium is found which has the same equation of motion with an anisotropic density tensor as a periodically layered fluid, but which has a constitutive relation relating pressure and dilation which is nonlocal in space and time. This equivalent medium exhibits the same wave propagation properties as the layered solid, fluid medium in the long wavelength limit and is called an elastoacoustic medium.


We discuss macroemulsions stabilized by silver interfacial colloidal films and the effect of dithizone on them. These emulsions are characterized by a very sharp size distribution. We find that dithizone, which is known for its strong interaction with silver, strongly affects the state of flocculation of the colloid. The size of the flocs can be related quantitatively to the droplet size. Dithizone also affects the rate of nucleation of the colloid, which is also expressed in a measurable reduction in the droplet diameter. The adsorption of dithizone on silver hydrosols and organosols and its spectroscopy are also studied. Using Raman spectroscopy, we find that dithizone adsorbs on hydrosols in a structure similar to that of silver dithizonate. S-atom and azo-N-atom bonds with silver are formed in an end-on, perpendicular orientation. In the interfacial colloid the dithizone is present predominantly in a disulfide form.


In this work, the aim was to measure the Contrast Sensitivity Function (CSF) among patients with, and healthy volunteers without this pathology. The subjects of the tests were 12 female volunteers, aged 20-37 years — six of them with migraine, and six other ones without migraine. CSF measurements were performed using static visual stimuli of angular sine-wave gratings, with spatial frequencies of 2, 3, 4, 24 and 64 cycles/360o. Method used was the psychophysical one, with forced choice between two temporal alternatives, conditions of photopic luminance (screen average luminance of 41 cd/m2), and binocular vision with natural pupil. The results demonstrate that visual perception of contrast by the volunteers with migraine was lower in the frequencies of 2, 3, 4 and 64 cycles/360°. These preliminary findings suggest changes in the CSF related to this pathology. 05 Psico-inglês 22-1.pmd 28/9/2011, 07:47 81 82 EVALUATION OF CONTRAST SENSITIVITY... LIANA C. MENDES, MELYSSA K. C. GALDINO, JÁKINA G.VIEIRA, MARIA L. B. SIMAS E NATANAEL A. SANTOS 3


Tamonontamo (2012) is a piece for amplified vocal quartet, choir of 24 singers and live electronics. The focus of this article is the work made in collaboration with the Real-Time Music Interaction Team of Ircam. Augustin Muller, computer music programmer working with the first author at Ircam for this project, upgraded the CataRT software adding a Spat~ module to relate the corpus-based synthesis with the spatialization. In most works, the spatialization of sounds depends on the aesthetic choice of the composer. The Spat~ software allows the drawing of linear movements of a source among a pre-selected number of loudspeakers with a user-friendly graphical interface. In this patch, we used Spat to spatialize the sounds in a non-linear way. The logic of spatialization depends on the pair of audio descriptors chosen in the set-up of the CataRT graphical display. In this sense, the aesthetic ideas of the composer refer not locally to each sound but on the choosing of the audio descriptors used for the x, y axis. A further Spat-related display has been implemented to split the space used for analysis/playing from the space used for diffusion of sounds. The implementation of the Unispring algorithm in the mnm.distribute external Max/MSP object allows the distribution of grains, rescaling their position inside a pre-drawn sub-space. The interpolation between different shapes or the change of audio descriptors on the x, y axis for both displays can be programmed and made in real time. The storage of the synthesis as database (in a text file), allows the analysis to be recalled, recovering the shapes drawn previously. Hiding and permanent deletion of some selected corpora in the database is also possible. The use of colour to work on the z axis is possible and is among the next steps of this work. The upgrade of the use of Spat~ to an ambisonics system for diffusion of sounds represents the possibility to make-through the use of concatenative synthesis?a genuine work of 3D-sound-sculpting.


This article investigates the switch from Frisian to Dutch as a written medium among the members of the secular clergy in West Friesland in the 15th and 16th centuries. In the 15th century the preferred written language of wordly priests of Frisian origin turns out to have been Frisian, whereas Dutch seems to have been favoured by priests of non-Frisian stock. rom about 1520 the use of Frisian among priests of Frisian origin rapidly declined. During he period 1530-1550 Frisian as a written medium was still in use among certain, probably lderly, priests, but its use now depended on the situation or the wishes of the people they rote for. By 1550 the switch from Frisian to Dutch must have been virtually complete.


The companion article in this issue, "A simple, robust algorithm for seismic net pay estimation" (hereafter referred to as Net Pay 07) outlines a method to estimate net pay from band-limited impedance seismic data. The objective of this second article is to describe a procedure to estimate the uncertainty of these net pay predictions.


Recent developments in animal psychopharmacology were reviewed with special reference to our 10-year studies in confirming the disinhibitory theory of chlordiazepoxide in frustrative nonreward (rats), spontaneous alternation (rats), discrimination reversal (rats), successive discrimination (rats), go/no-go type descrimination (rats, monkeys), passive and shuttle avoidance (rats) and differential heart rate conditioning (rats). Although anticholinergics have a similar behavioral function, their sites of action seem to be different because of their effect on the hippocampal electrical activity is markedly distinct from that of chlordiazepoxide.


Alwashliyah is a da'wah organization with a different culture from the society in which the organization was born. This article aims to reveal the map of Aljamiyatul Washliyah's da'wah and other socio-religious organizations in West Java. The data to inform the theme of Alwashliyah da'wah is qualitative. Meanwhile, the socio-historical approach is used as an analytical tool and comparative to sharpen the map of the da'wah movement further. As for Alwashliyah's da'wah activities in West Java, namely: First, it was started in 1956 in the northern region of West Java through educational approaches and social activities; second, the da'wah method is carried out through tabligh, tadbir, tathwir. Alwashliyah da'wah in West Java is still concentrated in education and religious studies. Just like the da'wah of similar organizations. So that competition occurs in carrying out da'wah because the targets and forms are identical, impacting the inclusion of internal religious sentiments.


Nanomaterials are finding increasing application in nano-, opto-, radioelectronics, etc. Their structural perfection becomes critically important. To establish dependence of the properties of these objects from their structure one requires detailed structural diagnostics. The decreasing the size and increasing the complexity of the physical processes in the studied substances makes it impossible to analyze by any particular method only. It becomes necessary complex application of X-ray, synchrotron, electron-microscopic methods of diagnosis with thorough assessment of the technological processes of the structures growth, as well as a comparison of these data together with the functional properties of the materials. The above-described integrated approach has been applied to a variety of promising nanoscale multilayer heterostructures, which are used in spintronics, optoelectronics, radiophysics, etc. The results of investigation of the real structure of these systems by a set of X-ray synchrotron methods of analysis, as well as by electron microscopy are presented. Joint analysis of electron microscopy, and X-ray microanalytical data for the metallic magnetic periodic systems Fe-Cr-Gd with different thickness and composition superlattices was made. Structural features of these heterostructures allowed to explain the experimentally observed differences in the magnetic properties of complexes of Fe/Cr/Gd and Gd/Dy. Firstly, these systems are characterized by the occurrence of 2-3 monolayers thick sublayer close to Gd interfaces, inside which there is an increasing of the magnetic moment of Gd. The second feature of the systems Fe/Cr/Gd (and FeCo/Cr/Gd systems) is the reducing of the magnetic moment as compared with the bulk of Gd and with the superlattice and Gd/Fe/Gd system. Objects on the basis of alternating layers of Gd/Dy studied as an example of chiral-ordered magnetic nanostructures It has been established that Gd in the superlattice is almost completely dissolved in Dy indicating by the absence of domains with Gd content of 100%. The influence of the crystalline quality of the layers of studied heterostructures depending on the choice of specific materials was demonstrated. It was made a joint analysis of the X-ray, and synchrotron electron-microscopic methods data of nanoscale multilayer heterostructures GaAs/InBiAs/GaAs in which the bismuth atoms are incorporated in the crystal lattice in place of the arsenic atoms. Restored structural characteristics of these advanced materials for optoelectronics allowed to clarify the features of their electronic properties which are critical for the production of semiconductor lasers and modulators. Investigation of the structure of multilayered heterocomposition containing formed quantum wells and quantum dots of InBiAs clarified the peculiarities of the electronic band structure within the samples. A comprehensive study of the nanoelectronic materials structure by broad set of methods allows to clarify the behavior of charge carriers under the influence of quantum effects, which not only has implications for the technological application of the studied material, but also allows to analyze the fundamental characteristics of their physical properties.


Abstract : This technical note reports what appears to be a hitherto missing piece of barrier-patrol theory: the solution of the equation for a stationary (also known as symmetric ) tight crossover barrier. It has long been known, at least implicitly, that the equation in question is cubic in the ratio of searcher speed to target speed. The exact solution is derived here; it is algebraically complicated. The key result of this note is the identification of a remarkably simple approximate solution that is remarkably accurate for barriers wider than a few times the effective sweep width of the searcher s sensor.


Obese patients who have diabetes have higher cardiovascular disease (CVD) morbidity and mortality than individuals without diabetes, and about 70% of mortality in patients with diabetes is caused by CVD events, including coronary heart disease (CHD), hypertension, heart failure, and stroke (1). Data from the Framingham Heart Study (FHS) show that individuals with diabetes have double the CVD risk in men and triple the risk in women after adjusting age, smoking, hypercholesterolemia, and hypertension (2). Furthermore, experimental and clinical studies have found that endothelial dysfunction may play a key role in the impairment of arterial relaxation and the promotion of thrombosis and neointimal proliferation and that these abnormalities are characteristic features of atherosclerosis and associated CHD in patients with diabetes (3). With the progression of atherosclerosis, coronary arteries become obstructed and hypoxia and ischemia occurs (1,3). In response to myocardial ischemia and hypoxia, angiogenic factors including nitric oxide (NO) and vascular endothelial growth factor (VEGF) are mobilized and activated (1,3). VEGF promotes endothelial cell proliferation via its receptor VEGF receptor 2 and stimulates endothelial NO synthase (eNOS) activation for NO production via VEGF receptor 1 (4). Other factors such as angiopoietin-1/2, platelet-derived growth factor BB, matrix metalloproteinases, and fibroblast growth factor also participate in angiogenesis and the maturation of blood vessels (4).

Hypoxia inducible factor 1 (HIF1) is one …


Aiming at the maximum lifespan problem of multiple source and base stations in Wireless Sensor Network(WSN),this paper proposes a communication model based on optimization theory.It establishes integer nonlinear programming model according to the WSN data flow restrictions and energy conservation principle,with the maximum lifespan network for the best goal,makes energy and bandwidth as a limitation on the constraint conditions,uses optimization technology of distributed algorithm to solve the model.Simulation results show that,in many of the base station environment,this model can prolong the network life period.


Entrepreneurship education is the new requirement for higher education and needs for vocational colleges in remote areas to ease the severe employment situation,and also the need for the survival and development of higher vocational colleges.It has positive significance to guide and encourage the college students to participate in the society.But the entrepreneurship education in vocational colleges in remote areas in China has some problems such as the limited attention of the government and the colleges, shortage of teachers and lack of practical training.The best way to improve the entrepreneurship education is to deepen the study of the theory of entrepreneurship education,strengthen the practical training and the education faculty construction.


The paper reviews the literature on adaptive learning in macroeconomic settings where the formation of expectations is particularly relevant. Special attention will be given to simple two-period overlapping generations models with a unique fixed point perfect foresight equilibrium; in this kind of scenario, eventual long-term periodic and a-periodic cycles are exclusively the result of the process of learning. The outcome that high rates of money growth have a potentially destabilizing effect generating periodic fluctuations and chaos is emphasized. The persistence of systematic forecast errors in a scenario where agents are supposed to act rationally is relevant in this context and it will be thoroughly discussed resorting to the notions of self-fulfilling mistakes, consistent expectations equilibria and beliefs equilibria.


Abstract The chain-ladder method is one of the most popular claims reserving techniques. The aim of this study is to back-test the chain-ladder method. For this purpose, we use a stochastic scenario generator that allows us to simulate arbitrarily many upper claims reserving triangles of similar characteristics for which we also know the corresponding lower triangles. Based on these simulated triangles, we analyse the performance of the chain-ladder claims reserving method.


7,8,9,10-Tetrahydro-6,6,9-trimethyldibenzo[b,d]pyran and 5,6,7,8,9,10-hexahydro-6,6,9-trimethylphenanthridine have been prepared by reaction of pulegone with lithium ortho-lithium phenolate and lithium ortho-lithium N-trimethylsilylaniline. The cyclization into the annellated systems could be performed under essentially non-acidic conditions.


We compare THz wave generation performances of diabolo-shaped spintronic antennas with 3 nm, 100 nm and 200 nm Pt thicknesses at the antenna flares. The center of these antennas where spin-to-charge current conversion occurs is composed of 2 nm Fe and 3 nm Pt metal layer. THz- time domain spectroscopy (THz – TDS) showed the most efficient emission, especially at frequencies <1.5 THz, from the diabolo antenna with 200 nm Pt layer. We also compare THz emission amplitude of diabolo and rectangular spintronic antennas composed of2 nm Fe and 3 nm Pt layer at the center and 2 nm Fe and 200 nm Pt layer at the displacement current direction. Time-domain and frequency-domain waveforms showed higher emission amplitude from the rectangular antenna especially at frequencies >1.1 THz.


[Objective]The paper was to study the contact toxicity and anti-feeding activity of Aconitum flavum against cabbage worm.[Method]Insect dipping method was adopted to determine the contact toxicity of the extracts of A.flavum extracted from five polar solvents including ethanol,petroleum ether,ether,ethyl acetate,n-butanol and water;leaf dish method was adopted to determine the anti-feeding activities of five solvent extracts including ethanol,petroleum ether,ether,ethyl acetate,n-butanol and water against cabbage worm.[Result]Extracts of A.flavum had high contact toxicity against cabbage worm,when the concentration was 100.00 mg/ml,the corrected mortality at 48 h reached 97.24%,and the insecticidal activities of five solvent extracts against cabbage worm in sequence were watern-butanolethyl acetateetherpetroleum ether,the corrected mortality of water extract at 48 h was 95.87%;the anti-feeding activities of five solvent extracts in sequence were watern-butanolethyl acetateetherpetroleum ether.[Conclusion]Extracts of A.flavum had strong contact toxicity and anti-feeding activity against cabbage worm,and the active ingredients with contact toxicity and anti-feeding activity might be a kind of polar compound.


Types and traits of authigenic silica and chert The previous article in this series on silica mobility in evaporitic settings focused on the most mobile (soluble) form of silica known as opal-A or amorphous silica which is defined by a broad peak in XRD determinations (Figure 1). Based on that discussion, it seems there are three main ways modern amorphous silica precipitates; 1) Inorganic precipitate (as in the crusts of the Coorong ephemeral lakes, 2) As a replacement of sodium silicates, such as magadiite (as in alkaline lakes in the African Rift Valley, and 3) Biogenically as in diatom and radiolarian tests in various lakes and the oceans. In all three Opal-A (amorphous opal) is the dominant form of SiO2, but there are other more crystalline forms of sedimentary silica Quaternary sedimentary settings with additional opaline and more quartzose forms. Knauth (1994) classified authigenic silica into, a) 3 types of amorphous opal (opal-A, opal-CT, and opal-C) and, b) 5 types of quartz (granular microcrystalline quartz, megaquartz, length-fast chalcedony, length-slow chalcedony, and zebraic chalcedony).


Chipozi zhuan (Biography of a foolish woman) is an erotic novel in Ming dynasty, of which the female first person narrator makes it unique and eye-catching. Many studies have discussed this novel concerning its author's identity, delivery as well as images of sex and gender. Regarding the issue of female image, a common-seen view is that the female protagonist of Chipozi zhuan is placed as a role of victim, which rationalizes her sexual misconduct and criticizes the patriacrchal culture indirectly. However, narrations of Chipozi zhuan relative to active or passive sexual roles seem to reflect other implication about sex and gender. This article mainly focuses on the sexual subjectivity of the female protagonist in Chipozi zhuan, and adopts a text-centered inter-disciplinary methodology, which not only focuses on the original content of novel but also embrace perspectives and knowledge from feminism, sociological theory and historical materials. This kind of analysis show that female sexual subjectivity in Chipozi zhuan is illusory and constructed based on a male perspective, which mainly shown from three perspectives: the denial to female desire, the rationalization of male violence through depicting female pleasure in extreme passive sex as well as the association between social class and sex.


Hydrogen energy is considered as one of the most ideal clean energies to replace fossil fuels because of its high energy density, recyclability and environmental friendliness. The design and development...


In this study, based on the physical and mechanical parameters of Camellia oleifera, the mechanical model of Camellia oleifera was rebuilt and analysed to reveal the damage mechanism of fruit shell breakage. The results revealed that under the same conditions (e.g., axial loading form), the stress of the fruit uniformly diffused from the extrusion point to the periphery and depth, and the maximum equivalent stress was 9.4104 Mpa. While under radial loading, the stress of the fruit extended axially along the dorsal line of the tea seed, and the maximum equivalent stress was 6.9467 Mpa. The maximum stress under the two loading modes occurred at the joint between the middle column of the shell and the calyx. The increased loading displacement decreased the stress on the fruit, making it easier to break the shell of Camellia oleifera by radial extrusion. The results can serve as a reference for the development of different equipment to break the shell of the Camellia oleifera fruit.


In the near field recording (NFR) system, there always exists the possibility of collision between solid imersion lens (SIL) and media owing to dust, scratches on the media, and external shock because of the extremely small gap distance. The kinetic energy associated with damage from shock is directly proportional to the square of velocity, and the phase of velocity is faster than the phase of displacement with 90°. Thus, it is effective to prevent a collision on the basis of velocity information. The velocity of the actuator in the NFR system should be estimated by an observer without using a velocity sensor. In this paper, we propose an improved protection process with a mode switching servo method using a Luenberger observer. The gap distance state can be estimated earlier by detecting the velocity state yielded by external shock. Through simulations and experiments, we confirm that the protection process based on velocity and gap distance is more powerful than the protection process based only on the gap distance.


An exploratory data assessing review survey from previously reported data was conducted in Ethiopia to identify the breeding objectives and trait preferences of farmers in chicken production. Wilcoxon, signed ranks test from the scattered data for breeding objectives of the respondents were incomes, cultural/religious reasons, more meat and egg production with the overall index value of 0.3, 0.27 0.22 and 0.21, respectively. Overall genetic improvement of the preferred traits were varied in sexes like comp type, plumage color, body weight, breeding ability and body conformations with the index values of 0.25, 0.23, 0.22, 0.22 and 0.08 for males and 0.09, 0.22, 0.20, 0.23, 0.26, respectively for females through uncontrolled breeding. Highly preferred traits are a good predictor of the breeding objectives of chickens' production. In general, traits are important for selecting chickens a market for meat for consumption and breeding purpose in Ethiopian Therefore, this Preference Traits and Breeding Objectives of Farmers are important to improve the genetic part of chickens in the country.


Distributed Bragg reflector (DBR) lattice‐matched Pb1−xSnxTe/PbSeyTe1−y diode lasers were fabricated using liquid phase epitaxy. These DBR lasers were operated within a limited range of heat‐sink temperatures 8.5–38 K, and the threshold current density at 20 K was ∼3 kA/cm2. Single longitudinal‐mode operation was obtained up to more than three times the threshold current. The DBR lasers exhibited continuous tuning over a relatively wide range of ∼6 cm−1 near 775 cm−1 (12.9 μm). The average tuning rate was 0.21 cm−1/K, and it was much smaller than the rate for corresponding Fabry–Perot lasers, which was 2.3 cm−1/K.


Objective To study the selective inhibition of a polysaccharide from Acanthopanax giraldii Harms var. hispidus Hoo(AGP) on human gastric cancer cells, human embryonic tendocytes and human lymphocytes of the peripheral blood of healthy subjects. Methods The morphology of the cells was observed with optical microscopy and MTT was used to examine their activity and functions. Results AGP exerted selective inhibition on the activity and function of human gastric cancer cells, slight inhibition on human embryonic tendocytes and no inhibition on human healthy lymphocytes. Conclusion AGP may be used safely to prevent or treat gastric cancer due its selective inhibition on the activity and functions of human gastric cancer cells.


With the development of society,there has been a more and more obvious presence of the characteristic of audience-segmentation in human activity over information spreading,and user classification has also become an important research topic.So the article carried out a study over online social network user from multiple perspectives which mainly include user classification based on interested topics and preference,classify interests of social media user based on information content and topological relation,and both them respectively.For user classification based on information content,we adopted LDA to extract the topic distribution from the content posted by users.And the distribution is used in support vector machine,decision tree,Bayes and other multiple models to classify interests of users.For user classification based on topological relation,we found that users with same interests tend to have more common fans,and based on this finding we built classification models to classify users.Then,we proposed methods of combining information content and topological relation to classify users.Based on the experiments using Twitter data,we found that the combined method outperforms the one based on information content or topological relation.


The therapeutic effect of sulpiride was studied in 33 patients with vertigo, dizziness, and a tendency of depression.They were given oral sulpiride, 150 mg daily, and the subjective symptoms and objective findings were recorded before and two and four weeks after the start of treatment. The efficacy of the drug was evaluated; 7.4% showed marked improvement, 51.9% marked or moderate improvement, and 100% more than slignt improvement was seen in the fourth week. Many subjective symptoms, such as nausea and vomiting, headache, loss of appetite, stiff shoulders, general fatigue, obstructive sense of ear, as well as vertigo and dizziness, were also reduced.Righting reflex and gaze and positional nystagmus were significantly improved.The scores of SDS and CMI decreased markedly at the second and fourth week.Only four patients complained of side effects, which were liver dysfunction, and galactorrhea.In conclusion, sulpiride is useful in the treatment of vertiginous patients who have a tendency of depression.


Two species of iodide ions (I3− and I5−) are found in iodine—nylon 6 complexes. Orientation of I5− arrays (most likely I2/I3− complex) along the polymer chain and I3− ions perpendicular to the chain axis in uniaxially drawn films and in films with planar orientation suggests that there is and intrinsic relation between the direction of iodide ion arrays and nylon 6 chains. When an unoriented film of nylon 6 in the amorphous or the α crystalline form is treated with an aqueous solution of iodine—potassium iodide, the I3− species in the resulting iodine—nylon complex lie in planes parallel to the surface of the film, and I2/I3− units are oriented normal to the surface of the film. The γ form obtained by desorbing the iodine from this complex shows considerable uniaxial rientation with the nylon chains oriented perpendicular to the plane of the film; this orientation is maintained during the γ to α transition. It is proposed that the iodine-induced orientation of the nylon 6 chains is due to the nucleating effects of the iodide ion species as the iodine diffuses unidirectionally into the film.


This study on sixty albino rats divided in four groups. Group A was control, B exposed to radiations one hour daily (Cell phone2G 900-1900 MHz), C given Curcuma longa (turmeric)orally(166.5mg/kg/day) emulsified with olive oil and D exposed to both radiations and Curcuma longa orally. After 2 month of exposure animals, sacrificed by cervical dislocation then heart dissected out, preserved, processed and stained with H & E examined under microscope. Observations of myocardium in group B shown amorphous deposits, inflammation and mononuclear infiltration, congestion, karyopyknosis. while structural enhancement in group C than group A and minimal effects in group D than group B. Concluded that Regular cell phone exposure has produced, alteration in cellular and nuclear structure which could be minimized by using turmeric in proper manner. _______________________________________________________________________________


People say the grass is greener on the other side. I wouldn't know about that. I've never seen green, and I've never seen greener. I have felt grass, though. Soft grass through my fingers at the park, dry grass during a drought, grass that's full of prickles, grass covered in the morning dew, and rough edged grass which tickles and itches your neck when you lie down in it. The book I read while lying in the grass describes the sunset to be as warm and rich as a cluster of autumn leaves, with spears of golden light piercing through the cracks, the centre burning like a giant orange on fire. My mind races to keep up with the beauty of the vision my imagination creates. Fire has warmed me, burned me, given me hours of pleasure from the crackling sounds that break the stillness of the evening. I have even eaten an orange wrapped in foil and heated in the warm embers of a fire. The thermal juice of the citrus hit the roof of my mouth and danced on my tongue. It filled my throat, then my chest with its warmth, enveloping me like a blanket from within. I have crushed autumn leaves in my hands, too, and rubbed the texture of the veins between my fingers. But, not in colour. Not in sight. My fingers run through the words, eager to see more. More of the life that surrounds me. A child is walking by and stops to stare at the spectacle that is me - me in my glory. 'Is that man a pirate, mummy?' 'Shush, Eva. He can't see. Come away' 'But why are his legs so tiny? Even smaller than a baby. Except there are no toes, just plain skin. Why is...' Her words cut off. Now comes the usual hurried rustling of a parent, mortified by their child's words. They are trying to stifle the risk of further unintentional insult. They don't want to hurt me, to offend me. But they don't realise that I like it. I like to hear how other people see me. How I look, what I compare with. I smile as I recall a memory. Treasure Island was one of the first books I read in Braille. I was eleven. I remember the fearsome pirates. That was me in the eyes of this child. For those few seconds I was able to borrow those eyes and gaze, like into a mirror, and see. See myself. The rumbling of the sky warns of rain. I throw the book into my backpack and heist myself onto my hands. My muscles ripple and I feel a sense of strength and freedom balancing on one hand to attach my bag to the wheelchair. Pulling myself in I begin the journey home. Peak hour is always a difficult time to travel. My cane pushes at the leg of a woman. 'Do you want me to guide you through this?' I pull the lever backwards to slow my chair to a halt. She has a soft, sympathetic voice. It makes me feel pathetic. 'I should be right. Thanks.' Her tone stays pleasant, but becomes more how I'd picture her speaking to other men. 'You think that, but you almost tripped me over.' I smile. 'Sorry. I mustn't have seen you there.' She laughs. A tinkling, light kind of laughter with a musical lilt. 'Are you headed somewhere nearby?' Two streets down. Elizabeth Street. That's where I live.' I hesitate. 'But I thought I'd stop for a drink at The Coffee Club first.' I scratch the back of my neck. 'If you have time ...? breathe, gathering courage. A deep, rich baritone slices my moment's preparation like a paper-cut. 'Hi beautiful!' I hear the exchange of a kiss. She drops her voice and whispers that she is helping me to get home. His voice cuts the air again, this time louder, and much slower. Too slow. 'Where do you need to go?' I have heard that when you are embarrassed your face can show it by turning red. MeI tried to help me see the colours of the world through music. The colours of life, she would say, vary like notes in music. Sometimes they're major, sometimes they're minor. Sometimes louder, sometimes softer. Each change allows you to feel an emotion. …


From six aspects,the lesson's preparation, communication betw een teacher and student, guide for students' interest in Wushu, stimulati ng prac tice, teaching language and methods, and so on,it is deeply discussed on the application of teaching art in the college Wushu course by the way of docu ment and teaching practice in this article.


Background Cognitive dysfunction and high-order psychopathologic dimensions are two main classes of transdiagnostic factors related to psychiatric disorders. They may link to common or distinct core brain networks underlying developmental risk of psychiatric disorders. Method The current study is a longitudinal investigation with 11,875 youths aged 9-to 10-years-old at study onset, from the Adolescent Brain Cognitive Development study. A machine-learning approach based on canonical correlation analysis was used to identify latent dimensional associations of the resting-state functional connectome with multi-domain behavioral assessments of cognitive functions and psychopathological problems. For the latent rsFC factor showing a robust behavioral association, its ability to predict psychiatric disorders was assessed using two-year follow-up data and its genetic association was evaluated using twin data from the same cohort. Result A latent functional connectome pattern was identified that showed a strong and generalizable association with the multi-domain behavioral assessments (5-fold cross validation: ρ = 0.68~0.73, for the training set (N = 5096); ρ = 0.56 ~ 0.58, for the test set (N = 1476)). This functional connectome pattern was highly heritable (h2 = 74.42%, 95% CI: 56.76%-85.42%), exhibited a dose-response relationship with cumulative number of psychiatric disorders assessed concurrently and 2-years post-MRI-scan, and predicted the transition of diagnosis across disorders over the 2-year follow-up period. Conclusion These findings provide preliminary evidence for a transdiagnostic connectome-based measure that underlies individual differences in developing psychiatric disorders in early adolescence.


An adduct of phenylglyoxal with thiamine was readily converted to phenylglyoxylate and thiamine by the action of organic hydride acceptors such as 2, 6-dichlorophenol indophenol, trityl cation, 2-methyl-3-benzylidene-indolenium salt and N-methylnicotinamide. Similar hydride transfer reaction was observed for the adduct of methylglyoxal with thiamine. Direct conversion of phenylglyoxal to phenylglyoxylate by 2, 6-dichlorophenol indophenol was found to occur in the presence of TPP and base. The results indicate a new catalytic role for thiamine in the conversion of α-ketoaldehyde to α-ketoacid.


One additional unit of savings this period augments the expected level of consumption next period by the net return on investment—net of next period's consumption. The result is a non-institutional explanation for a considerable portion of the equity premium and new model for pricing macro perpetuities.


If it is possible to have a heartwarming experience on a cold winter morning in Milwaukee, Wisconsin, this is such an occasion for me. First, we were personally and professionally delighted five years ago with the formation of the American Association of Bovine Practitioners. The vision and the statesmanship of your leadership at that time has resulted in immeasurable benefits to the dairy industry. Since our life, too, is committed to the welfare of those who own and tend the foster mothers of the human race, we welcome every increase in professional advancement which makes the dairy cow more efficient because of her improved health and regular reproduction.


Classification by machine learning is an important technique to predict gene functions. However, the positive data for many prediction data sets may be rare, which degrades the performance of functional prediction. Combined with support vector machine (SVM) algorithm, several common approaches to deal with the unbalanced problem were compared, including majority voting, the moving boundary surface, etc. We also proposed weighted ensemble strategies instead of simple majority voting to address the unbalanced problem. The experimental results show that the method of voting ensembles, which combines under-sampling majority technique and the ensemble learning idea, has performance superior to the method of moving boundary surface. The weighted strategies based on majority voting can achieve significantly better and more stable performance than that of other methods.


A process for the preparation of a backlit light image showing when illuminated from the front a day image (5) and when illuminated from behind a night image of the displayed objects, wherein the front side of a transparent image carrier (2) printed on the days image (5) and the back of the a to the contours of the days of the image (5) is suitable shading mask (6) associated with the image carrier (2) which covers the on the night image dark appearing objects opaque and on the night image appear bright objects wholly or partly exposes, characterized in that for the preparation of the shadow mask (6) the days image (5) is digitized and starting from the digital image data of day of the image (5) image data for the creation of the shadow mask (6) are generated using a computerized image processing program by using the image processing program for blacked out the night image OBJEK th of the daily image (5) labeled and darkened and marks the brightened for the night image objects of the image days (5) and are brightened wholly or partially, and ...