During the long operational time of a satellite,there is a large number of telemetry data which contain valuable information of satellite status change.Therefore,it is of great significance to mining the variation characteristics for detecting abnormal variations and performing fault diagnosis of a satellite.Aiming at the problems of in-orbit satellite telemetry data analysis and the fault diagnosis similarity searching,this paper described a mining algorithm of telemetry time series similarity based on Piecewise Regression Algorithm(PRA).Firstly,this algorithm was used to realize the dimension reduction through mining satellite telemetry data to reduce the data volume.And then the index tree of multidimensional space was established.The time sequence data of similar sequences were obtained through the seeking of the similarity threshold detection.The theoretical analysis and the simulation test of satellite power subsystem telemetry data show that the algorithm can effectively reduce the dimension and keep the data trend.The establishment of the similar sequence proveds the basis for satellite orbit data analysis and fault diagnosis.


An approach of immobilizing mobile crystalline material (MCM)‐41 mesoporous silica nanoparticles on the inner wall of an open‐tubular (OT) capillary as the support for coating chiral selector of cellulose tris(3,5‐dimethylphenyl‐carbamate) (CDMPC) was carried out. By taking advantage of the improved phase ratio of OT capillary with the immobilization of MCM‐41 mesoporous material, the cellulose derivative of CDMPC as the chiral selector was simply coated on the MCM‐41 nanoparticle layer via the hydrogen‐bonding interaction, and the enantioseparation was successively carried out. Eight pairs of acidic, neutral and basic enantiomers were resolved in capillary electrochromatography or capillary liquid chromatography mode. The concentration of CDMPC for coating was systematically investigated to obtain the optimized chromatographic properties on enantioseparation by controlling the supposed film thickness of CDMPC on MCM‐41 nanoparticle layer. Comparing with a bare fused silica capillary column coated with CDMPC under the same coating procedure as MCM‐41‐modified capillary did, the MCM‐41‐modified capillary column offered much higher enantioselectivity. This result indicated the significance of using the mesoporous nanoparticles as the electrochromatographic support to enhance the phase ratio of OT capillary column in capillary electrochromatography and capillary liquid chromatography. For investigating the effect of experimental conditions on the enantioseparation with this prepared OT capillary column, the content of organic modifier acetonitrile in the mobile phase was thus extensively evaluated to achieve a better chiral separation.


In contrast to the chemistry of momomeric η1-Pd allyls, which act as nucleophiles, and monomeric η3-Pd allyls, which act as electrophiles, relatively little is known about the reactivity of Pd complexes with bridging allyl ligands. Recently we demonstrated that PdI dimers containing two bridging allyl ligands react with one equivalent of CO2 to form species with one bridging allyl and one bridging carboxylate ligand. In this work we have prepared complexes from three different classes of PdI bridging allyl dimers: (i) dimers containing two bridging allyl ligands, (ii) dimers with one bridging allyl and one bridging chloride ligand, and (iii) dimers with one bridging allyl and one bridging carboxylate ligand. Complexes from all three groups have been characterized by X-ray crystallography, and their structures compared. Complexes with two bridging allyl ligands have the longest Pd bridging allyl bond lengths due to the high trans influence of the opposing bridging allyl ligand. For these species the HOMO i...


ABSTRACT The zone of intersection between land and sea within an urban context has long been viewed as a special type of urban commons. The well-researched port-city interface, however, tells a rather tragic story about the use and management of this valuable resource. This study asks how four major regulatory-institutional issues in the interface – land ownership, activities allowed in port area, planning autonomy, and public access – affect the ability of ports and cities to preserve elements of "commons" in urban coasts? Furthermore, it assesses if and how Elinor Ostrom's principles for overcoming commons-related tensions, could contribute to the management of port-city conflicts over land-uses in the Mediterranean urban coastline and the various questions that may derive from such an application. For these purposes the study combines a comprehensive literature review with the analysis of planning regulation and in-depth, semi-structured interviews of key-stakeholders in seven port cities across three Mediterranean countries. The common experience in these different cases suggests that through a strategy involving scaling-down spatial decisions or governance, and built-in mechanisms for spatial cooperation, ports and the cities that host them can find a new joint path, which will strengthen local synergies and the quality of urban, public space.


Objective To investigate the clinical significance of ultrasonographic guidance in percutaneous trans catheter intervention for the treatment of malignant pericardial effusion.Methods After the pericardial puncture under ultrasonographic guidance,a pigtail catheter was inserted to drain off the effusion.Certain anti cancer drugs was instilled into the pericardial cavity and the catheter was withdrawn when fluid did not re accumulate.Results In all the 15 cases studied,the effective rate was 100%,and the complete remission was 73.3%.Conclusion The ultrasonographic guidance in percutanous trans catheter intervention is useful for the treatment of malignant pericardial effusion.


Developmental coxa vara with spondylometaphyseal dysplasia-corner fracture type (DCV/SMD-CF) (Suttcliffe type of SMD) [OMIM184255] is a rare skeletal disorder characterized by short stature, short long bones, coxa vara associated with a distinctive triangular bone fragment at the infero-medial corner of the femoral neck, fragments in the lateral metaphyseal ends of some long bones, and changes in the vertebral bodieswhichappear short, tall, andovoid. Thedisorderusually becomes apparent after the children start walking. This syndrome was first described by Suttcliffe [1966] and has been subsequently reported by Cooper and Ponseti [1973], Felman et al. [1974], Kozlowski and Bellmore [1989], Langer et al. [1990], Kozlowski et al. [1992, 1993], and Lachman [1966]. A review of 18 cases, including three personal observations, has been reported by Currarino et al. [2000]. In the present letter, we describe a new patient affected by DCV/SMD-CF who in addition presented at birth with an apparently isolated tetralogy of Fallot. The patient was a preterm baby born to healthy nonconsanguineousparents.Themother (tertipara)was30and the father was 40 years old at the time of conception. A Cesarean section was performed at 33 weeks of gestation because of the appearance of toxemia. The last fetal echography showed apparently isolated short femurs. Birth weight was 1,560 g (25th centile), length 40 cm (10th centile), and head circumference 32 cm (75th centile). An echocardiograph performed at 1month of age following the appearance of a heartmurmur led to a diagnosis of Fallot tetralogy, which was surgically corrected at the age of 6 months. The psychomotor development was within normal limits. At the age of 3 years, an increasing left genu valgum was noted. A radiograph of the knee led to a diagnosis of osteochondrodysplasia. The girl was 31⁄2 years of age at the time of our first genetic evaluation.Weight was 11 kg ( 3 SD), height 82.5 cm ( 4 SD), and OFC 49.5 cm (25–50th centile), arm span 64.5 cm, U/L segment ratio 1.98. (NV for age1⁄4 1.275), hand length 10.2 cm (3rd centile), foot length 14.4 cm (3rd–10th centile). Craniofacial features were normal. The limbs appeared short [upper limb length 35.5 cm ( 4 SD), lower limb length 42.25 cm ( 4 SD)]. There were evident lumbar hyperlordosis, mild left genu valgum, mild lower limb asymmetry, and bilateral pes planus (Fig. 1). A total body radiograph showed diffuse irregular metaphyseal ends more evident in the distal radii (Fig. 2), in the proximal (Fig. 3), and distal tibiae. Irregular patchy metaphyseal sclerosis was also particularly evident. Small corner fractures were present in the lateral aspect of right and left distal radial metaphyses, in the medial aspect of right and left proximal and right distal tibial metaphyses and in the lateral distal metaphysis of the left fibula. The pelvis showed bilateral severe coxa vara, very short femoral necks with a vertical radiolucent gap and a triangular bone fragment in the inferior medial aspect of the right femoral neck (Fig. 4). The acetabular roofs and iliac bones were normal. A lateral roentgenogram of the dorso-lumbar spine revealed an ovoid shape of the vertebral bodies with anterior wedging in T11, T12, and marked hypoplasia of L1 (Fig. 5). The metacarpophalangeal profile (MPP) showed only a relative shortness of the distal phalanges. The other Z-score valueswere on average above the ''zero line'' (see the online Fig. 6 at http://www. interscience.wiley.com/jpages/1552-4825/suppmat/index.html). The Sutcliff type of SMD is an uncommon skeletal disorder easily distinguishable from other types of SMDs. An excellent review has been proposed by Currarino et al. [2000]. According to these authors, the main characteristics of this unique chondrodysplasia are: DCV, a radiograph finding not present in the first year of life, generally noted between 1.5 and 2 years


Rapid isothermal processing (RIP) based on incoherent sources of light is emerging as a reduced thermal budget (product of processing time and temperature) processing technique. As compared to stand alone annealing unit, the in situ RIP unit is very attractive for the next generation of devices. A number of unwanted physical phenomena can be suppressed or completely eliminated in the in situ RIP case leading to improved quality of materials when compared to their ex situ rapid isothermal annealed and furnace annealed counterparts. We have used in situ rapid isothermal processor for the in situ rapid isothermal chemical cleaning of InP and GaAs substrates and in situ metallization of InP and GaAs Schottky diodes. As compared to ex situ annealing, the negligible oxygen content at the surface and interface of in situ RIP samples result in better current‐voltage characteristics, lower and compressive stress values, as well as smooth and continuous morphologies of the ohmic contact. In this paper, we have highlighted the role of in situ RIP in the metallization of InP and GaAs devices.


Lead (Pb) is an important environmental pollutant causing significant public health problems in many parts of the world and may be implicated in the pathology of the liver. This study was designed for the assessment of liver functions in lead acid battery factory workers occupationally exposed to hazardous effects of lead in their workplace in Nnewi. A total of 78 apparently healthy individuals aged between 18 and 56 years were recruited for the study. Thereafter, 6ml of venous blood sample was collected from each individual into plain container for the evaluation of biochemical indices. Total protein (TP), Albumin (ALB), Total bilirubin (TB), direct bilirubin (DB), Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) and Alkaline phosphatase activity (ALP) were assayed using established standard laboratory methods. Results revealed no significant alterations in the levels of serum ALB, TP, DB, ANALYSIS 24(106), November December, 2020 Medical Science ISSN 2321–7359 EISSN 2321–7367


Integrating a hole transport small molecule into an emissive layer of a hybrid light emitting transistor lowers the optical turn-on voltage, improving overall performance of the device.Integrating a hole transport small molecule into an emissive layer of a hybrid light emitting transistor lowers the optical turn-on voltage, improving overall performance of the device.


There are environmental and sustainable benefits of partially replacing cement with industrial by-products or synthetic materials in cement based products. Since microstructural behaviours of cement based products are the crucial parameters that govern their sustainability and durability, this study investigates the microstructural comparison between two different types of cement replacements as nanopozzolan modified cement (NPMC) in cement based product by focusing on the evidence of pozzolanic reactivity in corroboration with physical and mechanical properties. Characterization and morphology techniques using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), energy-dispersive X-ray spectroscopy (EDS), and scanning electron microscopy (SEM) were carried out to assess the pozzolanic reactivity of cement paste modified with the combination of nano- and micro silica as NPMC in comparison to unmodified cement paste (UCP) of 0.5 water to cement ratio (w/c). Results were then substantiated with compressive strength (CS) results as mechanical property. Results of this study showed clear evidence of pozzolanicity for all samples with varying reactivity with NPMC being the most reactive.


In a nutshell, the preliminary condition for access to support from international organizations, in the framework of the G24, has been the conclusion of an agreement with the International Monetary Fund. This has meant introducing conditionality criteria (largely derived from stabilization experiences i LDCs), based on restrictive monetary policy, fiscal consolidation (i.e. drastic reduction of the fiscal deficit) and elimination of subsidies. Additional elements concerned the choice of one or more nominal anchors (needed for price stability), the exchange-rate regime and the use of income policy.


AIDS caused by HIV has been a significant global pandemic, which is continuously threatening with more than two million newer infections and more than one million deaths each year. Human interventions to prevent or to cure the disease have been paid off at large proportions, yet not to the extent of reducing or completely nullifying those two million newer infections each year. To prevent many novel vaccine approaches have been showing very significant success, but very slow to come in the pipeline process mainly due to theirs reduced efficacies at pre-clinical or clinical trials level. Recently it has been reported that cure from AIDS using a monoclonal antibody (α4β7) therapy along with ART has been highly successful in non-human primates. Taken together these novel advancements, I am very hopeful that the burden of AIDS pandemic may be reduced substantially in the coming days.


We have investigated the turbulent mean-field dynamo action in protoneutron stars that are subject to convective and neutron finger instabilities during the early evolutionary phase. While the first one develops mostly in the inner regions of the star, the second one is favored in the outer regions, where the Rossby number is much smaller and a mean-field dynamo action is more efficient. By solving the mean-field induction equation we have computed the critical spin period below which no dynamo action is possible and found it to be ~1 s for a wide range of stellar models and for both axisymmetric and non-axisymmetric magnetic fields. Because this critical period is substantially longer than the characteristic spin period of very young pulsars, we expect that a mean-field dynamo will be effective for most protoneutron stars. The saturation dipole field estimated by making use of the model of "global" quenching fits well the pulsar magnetic fields inferred from the spin-down data. Apart from the large-scale magnetic field, our model also predicts a generation of small-scale fields which are typically stronger than the poloidal field and can survive during the lifetime of pulsars. Extremely rapidly rotating protoneutron stars ($P \sim 1$ ms) may have a dipole field ~$(3{-}6)$ $\times$ 10 14  G.


Abstract Benzo[b][1,4]oxazines have been synthesized in good to excellent yields in the presence of the ionic liquid 1-butyl-3-methylimidazolium bromide [bmim]Br under relatively mild conditions without any added catalyst, The method offers the advantages of good yields and short reaction times, and the ionic liquid can be easily separated from the product and reused. GRAPHICAL ABSTRACT


The utility model discloses a horizontal activated carbon adsorption device. The horizontal activated carbon adsorption device comprises a box chamber shell, wherein a gas inlet is arranged at one end of the box chamber shell, the other end of the box chamber shell is provided with a gas outlet, and a non-woven fabric filtering cotton roughly-filtering layer, a molecular sieve layer and a plurality of activated carbon granule adsorption layers are sequentially arranged in the box chamber shell between the gas inlet and the gas outlet. The non-woven fabric filtering cotton roughly-filtering layer, the molecular sieve layer and a plurality of the activated carbon granule adsorption layers can sequentially remove dust, oil mist, moisture and organic waste gas in waste gas, has high treatment efficiency and can enable the waste gas to be changed into innocuous gas which can be drained directly.


For the grid-connected process of photovoltaic power generation, the grid-connected inverter is much more important. The current control strategy plays a significant role in the normal operation of the entire inverter and the system, as well as in the coordination and cooperation with other parts. On account of this, study the operating condition of the inverter with different current control strategies is of great significance. In this article, by establishing mathematical models, control performance of inverters with different current controllers is compared, which include the PI controller, the PR controller and the QPR controller. On the one hand, through theoretical derivation, the analysis proves that comparing to the traditional PI controller and ordinary PR controller, the QPR controller can not only realize zero error tracking, but also can follow the given waveform with no static difference near the fundamental wave and the gain will not be too high, making the system more stable. On the other hand, the simulation operation in MATLAB/Simulink compares the control effect of PR controller and QPR controller, and proves that the latter has better performance.


Abstract A unique technology for producing thermoplastic vulcanizate (TPV) has been developed using an intermeshing-type internal mixer (ITM). TPV produced by the ITM was compared with that produced using a co-rotating twin screw extruder (Co-TSE) to assess the former's commercial possibilities. TPV, originating from ethylene-propylene-diene monomer (EPDM) and polypropylene (PP), was produced by both machines with equal filled volumes, same shear rate, and same specific mechanical energy. Results indicate that ITMs can be used to produce TPV with mechanical properties comparable to those of TPV produced by Co-TSE. TPV can be produced with a lower shear rate with ITM compared to Co-TSE. A long residence time can be maintained in the mixing chamber of the ITM, allowing high conversion of the cross-linking reaction and resulting in better elastic recovery properties due to the higher cross-linking density. However, this resulted in higher viscosity of TPV produced by ITM.


In recent years, the prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing with a low-age tendency. Traditional Chinese medicine (TCM) is regarded as an effective therapy of NAFLD. The study on its etiology, pathogenesis, therapeutic principles and methods can provide new perspectives for the TCM treatments. This paper summarizes the progress in etiology of NAFLD with TCM in recent years, which can be concluded in the improper diet, overwork, emotional disorder, kidney asthenia of the elderly, TCM constitution, delayed disease progression and six exogenous pathogenic factors. Based on the theory of deficiency as primary and excess as secondary, the pathogenesis of NAFLD is related to dysfunctions of the liver, spleen as well as kidney and pathological products of the phlegm, dampness and stagnant blood. In terms of the pathogenesis and etiology, the therapeutic principles and methods can be divided into three points. Firstly, treating the primary focuses on soothing the liver and fortifying the spleen, warming yang for diuresis, dispersing liver qi for relieving qi stagnation, warming kidney for elevating yang. Secondly, treating the secondary puts emphasis on resolving phlegm and eliminating turbid, activating blood and resolving stasis. Thirdly, treating both primary and secondary concentrates on soothing the liver and fortifying the spleen combined with activating blood and resolving stasis, dispersing liver qi for relieving qi stagnation combined with eliminating dampness and heat, purging liver and gallbladder combined with dissipating phlegm and removing blood stasis, strengthening spleen and replenishing qi combined with dissipating phlegm and removing blood stasis, invigorating spleen and kidney combined with resolving phlegm and eliminating turbid.


The Canberra Mental Health Survey, carried out on a household cluster sample in late 1971, included a focus on the problems of youth, defined as the age group from 13 to 18 years (inclusive). Compared to their elders in the sample, this age group was more healthy, less disturbed and consumed drugs, tobacco and alcohol to a much less extent. There was even a suggestion in the survey results that adolescents may be less troubled than children indicating that, in Canberra, adolescence may be the happiest age of man. Preliminary results of this survey have been reported previously (Hennessy et al, 1973) and further prebiminary results are reported in this paper. Full computer analysis is not yet available. m e total survey sample was 1,422 (approximately 1% of the Canberra population) and this included 136 adolescents. The overall mep tance rate for interview was 92%.


Introduction: COVID-19 continues to be a global problem. Surabaya is among the cities hit by COVID-19. Lack of information and awareness of COVID-19 and its vaccination in teenagers might have impacted their preventative behavior and belief in COVID-19 vaccination. This study examined differences in high school students' understanding of COVID-19 and its vaccination before and after the intervention.
Methods: The quasi-experimental design was utilized in this study, which took place between September and December of 2021. PowerPoint materials (webinar), videos, and pocketbooks about COVID-19 and its vaccination were the educational community initiatives. Students in grades 10-12 at SMA 4 Muhammadiyah Surabaya, MA Mamba'ul Hisan Gresik, and SMA Negeri 1 Sidoarjo participated in the study, and 160 students completed the pre-test and post-test. The study variables were knowledge, student characteristics (gender, age, class, and school origin), and parental characteristics (age, education, and occupation). The paired t-test was used to evaluate the univariable and bivariable data.
Results: With an average pre-test value of 7.09 and a post-test value of 7.94, there was a difference of high school students' understanding of COVID-19 before and after the intervention (p < 0.001). Furthermore, there was also a difference of knowledge about COVID-19 vaccination (p < 0.001), with an average pre-test value of 5.87 and a post-test value of 7.03.
Conclusion: There are considerable differences in students' knowledge of COVID-19 disease and its vaccination before and after the intervention. In order to prevent COVID-19, community service activities involving the distribution of information (webinars), videos, and pocketbooks could help them gain more knowledge.


This paper presents a hybrid clustering algorithm and feed-forward neural network classifier for land-cover mapping of trees, shade, building and road. It starts with the single step preprocessing procedure to make the image suitable for segmentation. The pre-processed image is segmented using the hybrid geneticArtificial Bee Colony(ABC) algorithm that is developed by hybridizing the ABC and genetic algorithm to obtain the effective segmentation in satellite image and classified using feed-forward neural network classifier . Classification accuracy of hybrid algorithm is found better than well known KFCM, Moving KFCM.


If, as a result of a short mixing time, excess air entraining agent is added during the production of air-entrained concrete in order to achieve the required air content then the fresh concrete will contain air-entraining agent that has not been activated. If there is a subsequent input of mixing energy the air content of the concrete can rise. The extent of this rise (the re-activation potential) is affected substantially by the active substance on which the air-entraining agent (AEA) is based. A sufficiently long mixing time always avoids any rise in air content. Accurate understanding of the way the air void formation depends on mixing time is therefore very important for dependable production of air-entrained concrete that meets the requirements. The functioning of an air-entraining agent can be characterized in laboratory trials during extended initial testing. However, the air void formation is also affected by the mixer type, quantity of mixture, filling level and mixing intensity. The extent to which laboratory results can be applied to practical construction conditions has not yet been clarified. The air void formation in fresh and hardened concrete in relation to the mixing time was therefore determined in the laboratory and in a readymixed concrete plant in a research project. Comparison of the test series shows that the re-activation potential under practical conditions can be determined in laboratory trials.


The purpose of this work is to propose a derivation of a macroscopic model for a certain class of inertial two-phase, incompressible, Newtonian fluid flow through homogenous porous media. The starting point of the procedure is the pore-scale boundary value problem given by the continuity and Navier–Stokes equations in each phase β and γ along with boundary conditions at interfaces. The method of volume averaging is employed subjected to a series of constraints for the development to hold. These constraints are on the lengthand time-scales, as well as, on some quantities involving capillary, Weber and Reynolds numbers that define the class of two-phase flow under consideration. The development also assumes that fluctuations of the curvature of the fluid–fluid interfaces are unimportant over the unit cell representing the porous medium. Under these circumstances, the resulting macroscopic momentum equation, for the -phase ( = , ) relates the gradient of the phase-averaged pressure p to the filtration or Darcy velocity v in a coupled nonlinear form explicitly given by


In order to understand the interactions between surface processes and multilayer folding systems, we here present fully coupled three‐dimensional numerical simulations. The mechanical model represents a sedimentary cover with internal weak layers, detached over a much weaker basal layer representing salt or evaporites. Applying compression in one direction results in a series of three‐dimensional buckle folds, of which the topographic expression consists of anticlines and synclines. This topography is modified through time by mass redistribution, which is achieved by a combination of fluvial and hillslope erosion, as well as deposition, and which can in return influence the subsequent deformation. Model results show that surface processes do not have a significant influence on folding patterns and aspect ratio of the folds. Nevertheless, erosion reduces the amount of shortening required to initiate folding and increases the exhumation rates. Increased sedimentation in the synclines contributes to this effect by amplifying the fold growth rate by gravity. The main contribution of surface processes is rather due to their ability to strongly modify the initial topography and hence the initial random noise, prior to deformation. If larger initial random noise is present, folds amplify faster, which is consistent with previous detachment folding theory. Variations in thickness of the sedimentary cover (in one or two directions) also have a significant influence on the folding pattern, resulting in linear, large aspect ratio folds. Our simulation results can be applied to folding‐dominated fold‐and‐thrust belt systems, detached over weak basal layers, such as the Zagros Folded Belt.


The major overhaul and upgrading schemes for power generator No.5 (ТГВ-200 MW) of Qinghe power plant,the unique air-cooling mode and stator winding structure of this type of power generafor,special assembly process and improved groove blocks in particular,are discussed in detail.


Diabetic retinopathy is a diabetic disorder associated with human eye and it also remains as a common cause for blindness across the globe. Diabetic retinopathy is still diagnosed using fundus images from eye doctors due to insufficiently reliable automated DR detection mechanism. However, manual screening is the weakest, complex and time consuming process. Therefore, a computer based recognition technique with a deep learning approach is proposed to automatically recognize the deiabetic retinopathy images by classifying retinal fundus images into two different types. In this regard, this paper proposes an algorithm that incorporates an improved DR detection method aimed at increasing the efficiency. The deep neural network method called inception v3 is used for DR feature extraction. By adopting the transfer learning method, different image classification functions of the Inception V3 can be customized. For testing and training, totally 48 and 90 fundus images are used. The final classification is done by using the support vector machine algorithm, where input images are classified into two types namely, diabetic retinopathy image and normal retinal image.


In this paper,fracture reasons of YX2815 farm transporter frame are analyzed,which can provide the technical supporting for the users and frame design.


This study employs firm-specific announcements as a proxy for information flows and investigates the information-volatility relation using high-frequency data from the Australian Stock Exchange. Our analysis reveals a positive and significant impact of the arrival rate of the selected news variable on the conditional variance of stock returns, even after controlling for the potential effects of trading volume and high opening volatility. Furthermore, the inclusion of the news variable in the conditional variance equation of the generalized autoregressive conditional heteroscedastic model also reduces volatility persistence, especially with intraday data. Combined with the evidence that news arrivals display a very strong pattern of autocorrelation, our results are consistent with the Mixture of Distribution Hypothesis, which attributes conditional heteroscedasticity of stock returns to time-dependence in the news arrival process.


During investigation of hot band (01111110) oscillation spectrum in the TEACO2 laser,1,2 we have observed several lines in the 875–882 cm-1 range that have not been referred to in this band. These lines have not been identified due to insufficient monochromator resolution used in experiments and the absence of exact spectroscopic data at that time. Nevertheless, it has been supposed2 that these lines belong to a "double hot transition," for example, 10°0-20°0 (04°0) band.


A signaling role for cytosolic free Caz+ ([Ca2+Ii) in regulating Papaver rhoeas pollen tube growth during the self-incompati-bility response has been demonstrated previously. In this article, we investigate the involvement of the phosphoinositide signal transduction pathway in Ca2+-mediated pollen tube inhibition. We demonstrate that R rhoeas pollen tubes have a Caz+-dependent polyphosphoinositide-specific phospholipase C activity that is inhibited by neomycin. [Ca2+Ii imaging after photolysis of caged inositol (1,4,5)-trisphosphate (lns[1,4,5]P3) in pollen tubes demonstrated that lns(1,4,5)P3 could induce CaZ+ release, which was inhibited by heparin and neomycin. Mastoparan, which stimulated lns(1,4,5)P3 production, also induced a rapid increase in Ca2+, which was inhibited by neomycin. These data provide direct evidence for the involvement of a functional phosphoinositide signal-transducing system in the regulation of pollen tube growth. We suggest that the observed Ca2+ increases are mediated, at least in part, by Ins(l,4,5)P3-induced CaZ+ lncreased cytosolic levels of lns(1,4,5)P3 will stimulate the release of additional Caz+ from Ins(l,4,5)P3-sensitive intracellular stores. Cytoplasmic streaming in the forward direction occurs in the cytoplasm immediately adjacent to the plasma membrane and may contribute to the wave direction. The continued Ca2+ increase may occur as a result of a cascade or "domino" effect of activation of PICs, resulting in continued generation of Caz+ waves from the initiation site. When the wave reaches the pollen tube tip, inhibition of growth results, presumably due to the disruption of the Ca2+ gradient at the tip.


A new assessment method for water environmental quality in Cluster analysis method,, a lot of attention are attracted. An application of this method in water quality assessment of China is reviewed in the paper.


CATON-THOMPSON, G. The Zimbabwe Culture: Ruins and Reactions. Pp. xxiv+299. Illus. Oxford: Clarendon Press. 25s. Kharga Oasis. Man, 31, May, 77-84. LOWE, C. VAN RIET. Giant Crescents. A Brief and Preliminary Record of a Hitherto Unrecorded Culture in the Stone Age of South Africa. Trans. R. Soc. of S.A., 19, 3, 197-204. MIGEOD, F. W. H. Digging for Dinosaurs: An East African Giant. The Times, 21 Feb., 1931. OBERMAIER, H. u. H. KUHN, 1930. Buschmannkunst. Felsmalereien aus Sudwest-Afrika. Nach den Aufnahmen von Richard Maack. 64 S. 39 Taf. Berlin: Brandsche Verlagsbuchhandlung.


THE operative success of the otologic surgeon depends on his intimate familiarity with the temporal bone. An understanding of the anatomy of the bone and its heterogeneous contents as well as confidence in approaching them surgically is gained through long hours of cadaveric dissection. The resident is usually guided in this work by written descriptions and two-dimensional illustrations.A new and simple method of preserving the entire temporal bone with soft tissues intact has been, implemented by the Temporal Bone- Laboratory, University of Toronto. The method is applied to create a teaching collection of specimens which demonstrate anatomy, surgery and gross pathology to the surgeon in training.


The preventing and treating recurrent aphthous ulcer by Chinese diet was researched in recent years,the pathogenesis of recurrent aphthous ulcer in terms of traditional Chinese and western medicine was discussed.The results showed that the Chinese diet can effectively prevent and treat recurrent aphthous ulcer,How the functional components of Chinese diet acting on recurrent aphthous ulcers feasible methods of regulating body by Chinese diet and the applicating principle of Chinese diet,was summarized,to provide theoretical basis for developing intervention of recurrent aphthous ulcer by Chinese diet.


Calculation on magnetic entropy in a nanostructured superparamagnetic system has been carried out by means of both classical statistical thermodynamics and quantum theory. It turns out that there exists an optimal particle size for nanometer superparamagnets at which a maximum change of magnetic entropy is achieved, and that nanometer superparamagnets have an advantage of enhanced magnetocaloric effects over the conventional paramagnets within the wide distribution of particle size of nanometer materials. The enhanced magnetocaloric effects of nanometer superparamagnets revealed by the theoretical calculation mentioned above have been proved experimentally in the investigation of nanocomposite solid of Gd-Y alloy.


Neurocysticercois is a common neurological infection but intraventricular NCC is rare even in endemic areas. Here we discuss a case of intraventricular NCC located at foramen of monro leading to Bruns syndrome.


Objectives: To determine the prevalence and association of healthcare provider characteristics with exposure to any form of violence. To determine the frequency of change of workplace due to violence among medical doctors. Methods: The study was conducted at three Karachi government hospitals. Anyone who worked in outpatient, ward, or emergency department units of any age or gender was eligible to participate in the study. Surveys were conducted using a WHO-validated questionnaire, which included questions about exposure to violence and socio-demographic information. Results: Out of 300 people 52.7% were females and 47.3% were males. Chief Medical Officer /Medical Officers were twelve times more expected to be exposed to workplace violence than house officers. 26% of medical doctors had previously changed jobs. However, 19% of medical doctors had changed their workplace due to workplace violence. Conclusion: Violence of any kind was more common in doctors over the age of 35, and men were more vulnerable to violence. CMO/MO were more likely to engage in any form of violence than the rest of the profession. Last but not least, the frequency of medical doctors changing jobs due to violence was low. Keywords: workplace violence, healthcare workers, medical doctors, house officer, chief medical officer.


Tundikeri is a highly pre valent disease in pediatric age from 6 - 10 years of age. The recurrent attack of Tonsillitis makes the disease chronic and vulnerable for infectious diseases. Tonsils, the lymphoid tissue play important role in maintaining the immunity in children, hence ti mely treatment is most essential. Use of Saireyaka (Peeta) ( Barleria prionitis ) Moola Churna with Nimbuka ( Citrus limon ) Svarasa is a famous folklore medicine for Tundikeri in some regions of Karnataka state. Saireyaka (Peeta) is Tridoshaghna in action whi ch exactly correlates with Doshic configuration of Tundikeri. Considering the above points, the present study was planned to evaluate the effect of Saireyaka Moola Choorna in management of Tundikeri. Saireyaka Moola Choorna was given to 30 patients of Tund ikeri of 6 - 10 years. Patients were administered with 4 g of Saireyaka Moola Choorna ( Barleria prionitis ) with Nimbuka Swarasa as Sahapan for 10 days twice a day before food. With help of Brodsky assessment criteria gradation of symptoms was done. There was statistically significant effect of Saireyaka Moola Choorna (Barleria prionitis) (p < 0.001) on reduction of overall signs and symptoms of Tonsillitis. There was significant effect in TLC and ESR. Subjects also showed improvement in weight.


Experiments are conducted to study the variation rule of lubricating oil temperature during the working and cooling process for the trailer-mounted feed pumping unit of the 100 mm military field transportation pipeline.The mathematical tools such as data fitting and regression analysis are used to study the variation rules of the lubracating oil temperature when the pump works and idles separately.Based on the analysis of the influence factor of the lubricating oil temperature with pump's different modes,the mathematical model of the lubricating oil temperature variation is built.The research has a certain referential value for developing the simulator of the feed and booster pump unit of both 100 mm and 150 mm military field transportation pipelines.


The ultra short base line (USBL) underwater acoustic positioning in deep sea with digital data transmission is being studied. The goal of this study is improvement of the accuracy and expansion of the functions of the USBL for autonomous underwater vehicles (AUVs) and submersibles due to utilization of the transmitted data. To achieve the goal, the reliable data transmission with short positioning pulse must be ensured. The direct sequence spread spectrum (DSSS) is applied. The frequency band width of signal is 3 kHz with a center focus on 12 kHz for the deep sea use. From the ocean experimental data, it seems that the multipaths from the neighborhood have a dominant effect on the transmission quality. The results of investigation about this matter by experiments and simulations are shown. [This study is supported by a Grants‐in‐Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology in Japan.]


WHAT IS THIS SUMMARY ABOUT?
This is a summary of an article that reported results of a study using data from two phase 3 clinical trials called "PALOMA-2" and "PALOMA-3." Both PALOMA-2 and PALOMA-3 trials included women with HR+/HER2- advanced breast cancer. HR+/HER2- breast cancer means the breast cancer cells of these women have receptors for female sex hormones and little or no HER2 receptors. Both PALOMA trials tested the effect of adding a medication called palbociclib (brand name, Ibrance®) to a hormone therapy. Hormone therapy, also known as endocrine therapy, is a treatment that blocks or removes hormones that cause cancer cells to grow and divide. In both trials, women took endocrine therapy with either palbociclib or a placebo.

WHAT WAS THE AIM OF THIS STUDY?
The researchers aimed to see if the results from the PALOMA trials were similar for subgroups of women in the 2 trials. The subgroups in the study included women who shared certain features about their cancer or treatment history, for example, women whose cancer had spread to the liver. For each subgroup, the study compared the results from the 2 treatment groups: (1) women who took palbociclib plus endocrine therapy, and (2) women who took placebo plus endocrine therapy.

WHAT WERE THE RESULTS & WHAT DO THEY MEAN?
The same effect was found in all subgroups. Compared with those who took placebo, women who took palbociclib lived longer without their cancer getting worse (growing or spreading). Also, among women who had chemotherapy after stopping the trial treatment, those who took palbociclib started chemotherapy later than those who took placebo. Because palbociclib slows cancer growth and leads to tumor shrinkage, this may have played a part in starting chemotherapy later. These results show that palbociclib plus endocrine therapy is better at slowing the progression of advanced HR+/HER2- breast cancer than endocrine therapy alone. This can be said for women with different advanced HR+/HER2- breast cancer features and treatment history. Overall, the results support women taking palbociclib with an endocrine therapy if they have advanced HR+/HER2- breast cancer.


Following deep reform of our national economic social structure and multiple value concept,some college students moral beliefs exist such phenomenon as confused social idea,beneficial value choice and separated moral personality,which impacts college moral and talent education.Therefore,we must enforce the college student socialism education.


Palm date seeds were milled into two fractions: fine and coarse. Total dietary fiber (TDF) contents were found to be around 71 and 80% respectively. These fractions were used to replace flour in Sa...


Konaweeha watershed is the largest watershed in Southeast Sulawesi with Konaweeha River as the main river. The main issues in Konaweeha Watershed is floods that occur caused damage to infrastructure and public facilities, lowering agricultural production, and cause fatalities. One of the government's efforts to cope with the flooding problem in Konaweeha Watershed is planning the construction of multi-purpose dams in the upstream of Konaweeha Watershed that is Pelosika Dam and Ameroso Dam. Necessary to study the flood control performance of the two dams. Analyses were performed with hydrologic-hydraulic modeling using HEC-HMS software (Hydrologic Modelling System) version 4.0 and HEC-RAS (River Analysis System) version 4.1. The design rainfalls that were used as input to the model were 2 year, 5-year, 10-year and 25 year. Scenarios used in this study are: (1) Existing Scenario (2) Pelosika Dam Scenario; (3) Ameroro Dam Scenario; (4) Pelosika and Ameroro Dams Scenario. The results showed the maximum water surface elevation along the downstream of Konaweeha River in Scenario (2) and (4) were almost the same in the 2 and 5 years return period design flood. However, in case of 10 and 25 years return period, the difference of maximum water surface elevation at downstream of Konaweeha River was slightly significant. Furthermore, the damping efficiency of the peak discharge (at Probably Maximum Flood or PMF) was found to be 71.70% and 18.18% for the individual Pelosika Dam and Ameroro Dam respectively. Further discussion suggests the development of Pelosika Dam as the higher priority rather than that of the Ameroro Dam.


The composite bus system is a new type of satellite power system, which is suitable for high-power SAR satellites. The bus converter in the compound bus system is very important. This paper analyzes the design requirements of the bus converter, selects PSM LLC as the topology of the bus converter, and verifies the rationality of the scheme through simulation.


Purpose: In this modern jazz composition entitled "Perspektif", composers were exploiting 3 major aspects of music, which is: rhythm, melody and harmony. The main purpose in this piece is to persuade other composers to not only think creatively but to maximize and research deeply all the basic aspects of music. Research Methods: Modern jazz music can't be separated from the old school jazz and classical music. The key to be making innovative and creative composition was by learning the music from the previous era.  Results and Discussion: By learning the history and research deeply into all the basic aspects of music, the composers can easily come up with something innovative and creative, which in this case is combining jazz music instruments with different kind of sports as non-musical instrument. However, not only it features the sound of the sport but also playing advanced rhythm and filling the space what the music instruments can't do. Implication: In the process of making this composition from 3 major aspects in music, the composers got enlightened that all of each aspect has many different ways to be looked at or played at. Since the composers named this piece "Perspektif" with a format of 4 pieces jazz combo, 2 guys playing badminton, 1 guy playing basketball and the other 2 doing boxing.


In his latest book, David Roche compares the horror films of the 1970s with their remakes of the 2000s to answer the question which features as the book's subtitle: Why don't they do it like they used to? With disarming honesty as well as a rigorous theoretical framework, David Roche sets out to investigate why the remakes seemed to him less "disturbing" than the originals, using the criteria delineated by Laurent Jullier in Qu'est ce qu'un bon film? (15), especially that of cohesion. His ana...


The invention provides an integrated circuit (IC) fuse structure and a manufacturing method thereof. The method comprises the steps of: forming a contact aperture on a BPSG layer of a silicon substrate; forming a Ti metal layer on the surfaces of the contact aperture and the BPSG layer; forming a TiN layer on the surface of the Ti metal layer; forming a metal plug in the contact aperture; etching the TiN layer on the outside of the metal plug and exposing the Ti metal layer under the TiN layer; forming a metal layer on the surfaces of the metal plug and the exposed Ti metal layer; and photoetching and respectively etching the metal layer and the Ti metal layer under the metal layer into a metal strip and a Ti metal strip to form a fuse structure. The IC fuse structure does not include TiN materials, and can not form a metal molten mass or metal residuals in a fusing process, thereby effectively avoiding failure of a fuse fusing function, and furthermore guaranteeing product yield and qualified rate.


Altaras MM, Jaffe R, Corduba M, et al. 1990. Primary paraovarian cystadenocarcinoma: clinical and management aspects and literature review. Gynecologic Oncology 38:268–272. Darwish AM, Amin AF, Mohammad SA. 2003. Laparoscopic management of paratubal and paraovarian cysts. Journal of the Society of Laparoendoscopic Surgeons 7:101–106. Dietrich JE, Heard MJ, Edwards C. 2005. Uteroovarian ligament torsion of the due to a paratubal cyst. Journal of Pediatric and Adolescent Gynecology 18:125–127. Dueholm M, Praest J. 1987. Isolated torsion of the normal fallopian tube. Acta Obstetricia et Gynecologica Scandinavica 66:89–90. Goktolga U, Ceyhan T, Ozturk H, et al. 2007. Isolated torsion of fallopian tube in a premenarcheal 12-year-old girl. Journal of Obstetrics and Gynaecology Research 33:215–217. Grover S. 2007. Torsion causing interruption of the ampullary portion of the fallopian tube. Fertility and Sterility 88:968–964. Pansky M, Abargil A, Dreazen E, et al. 2000. Conservative management of adnexal torsion in premenarchal girls. Journal of the American Association of Gynecologic Laparoscopists 7:121– 124. Samaha M, Woodruff JD. 1985. Paratubal cysts: frequency, histogenesis, and associated clinical features. Obstetrics and Gynecology 65:691–694. Spigland N, Ducharme JC, Yazbeck S. 1989. Adnexal torsion in children. Journal of Pediatric Surgery 24:974–976. Vlahakis-Miliaras E, Miliaras D, Koutsoumis G, et al. 1998. Paratubal cysts in young females as an incidental finding in laparotomies performed for right lower quadrant abdominal pain. Pediatric Surgery International 13:141–142.


All books in this flagship series contain carefully selected substantial extracts from key cases, legislation, and academic debate, providing able students with a stand-alone resource. This chapter is concerned with proprietary estoppel. Proprietary estoppel is a means by which a party (B) can gain some protection against an owner of land (A), even if B has no contract with A and even if A has not formally given B a property right in relation to A's land. Proprietary estoppel is therefore a means by which B can obtain an equitable interest in A's land. It is noted that proprietary estoppel is very different from other forms of estoppel; so different that the term 'estoppel' is positively misleading. The chapter considers the requirements of a proprietary estoppel claim, including the role of unconscionability, how the courts determine the extent of any right arising through proprietary estoppel, and the impact of such rights on third parties.


Acute lymphoblastic leukemia is the most common malignancy in children and is characterized by numerous genetic and epigenetic abnormalities. Epigenetic mechanisms, which involve DNA methylations and histone modifications, result in the heritable silencing of genes without a change in their coding sequence. Emerging studies are increasing our understanding of the epigenetic role of leukemogenesis and have demonstrated the potential of DNA methylations and histone modifications as a biomarker for lineage and subtypes classification, predicting relapse, and disease progression in ALL. Epigenetic abnormalities are relatively reversible when treated with some small molecule-based agents compared to genetic alterations. In this review, we conclude the genetic and epigenetic characteristics in ALL and discuss the future role of DNA methylation and histone modifications in predicting relapse, finally focus on the individual and precision therapy targeting epigenetic alterations.


The axiomatic relationship between component quality control and reliability is explored analytically in this paper for a particular Quality Control procedure, and the effects on reliability of different versions of the procedure are quantified with the aid of simple examples. Theoretical relationships could similarly be developed for other quality control procedures. This could lead to an increased understanding of the relationship between quality control procedures and component reliability. These relationships could provide a theoretical basis for comparing different procedures, although the absolute values obtained may have no practical importance due to the well known difficulty involved in identifying probability distributions for component parameters.


Inclusion of planar layered media Green's Functions (GFs) is a major issue in the computational efficiency of full-wave models derived from integral formulations. These GFs may be decomposed into quasi-dynamic and dynamic terms. In a wide range of practical applications, the quasi-dynamic terms may be given in closed form. This paper proposes two criteria to establish when the complete GFs may be approximated by the quasi-dynamic terms. These criteria are based on simple relations between frequency, line length, dielectric thickness and permittivity. If these criteria are satisfied, the inclusion of the GFs into full-wave integral models is straightforward and the overall computational cost is strongly reduced. The proposed criteria are verified through a benchmark test case. The model is then used to perform a full-wave analysis of the power lost in a microstrip, as a consequence of the excitation of parasitic modes, such as surface and leaky waves.


We provide a HOL formalisation for analysing expected time bounds for probabilistic programs. Our formalisation is based on the quantitative program logic of Morgan et al. [21] and McIver's extension of it [17] to include performance-style operators. In addition we provide some novel results based on probabilistic data refinement which we use to improve the utility of the basic method.


Dr. Louis Lasagna, an accomplished physician and writer, again demonstrates his skills in his newest book. Dissatisfied with what has been written about venereal diseases, he has set out to describe concisely their biology, epidemiology, and some of the historical aspects. In a brief 150 pages he provides a wealth of information that should make interesting reading for our colleagues as well as for our patients, a rare combination in one book. The resurgence of gonorrhea and syphilis, despite the introduction of effective penicillin therapy 30 years ago, presents a fascinating and troubling epidemiologic and social problem. Dr. Lasagna is correct, I believe, in pointing out that one of the factors that accounts for this resurgence is the shift in diagnosis and therapy from the public clinic to the private physician's office. More physicians, especially those engaged in primary care, will have to become versed in the proper therapy of


In order to effectively control the natural gas pipeline risk,it is necessary to establish the synthetic pipeline emergency management.According to the characteristics of natural gas pipeline risk,this paper analyzes the natural gas pipeline risk from process spots,transportation pipelines,natural disasters and the third party destruction.Aiming at decreasing the natural gas pipeline risk and its hazards,specific natural gas pipeline emergency management is proposed from risk removing,plan preparing,emergency response and recovering.The results show that establishing emergency management towards risk characteristics contributes to control the risk of natural gas pipeline accidents and protect the normal operation of natural gas pipelines.


This study was aims to determine the microbial population and physical characteristics of frozen beef at different storage time. Fifteen sample packs of meat each 250 grams were used in the experiment which was conducted as One Way Experiment using a Completely Randomized Design with 5 treatments ( 0 week of frozen storage/freshmeat as a control, 2 weeks, 4 weeks, 6 weeks and 8 weeks), each treatment with three replications. The data were analyzed by ANOVA and Duncan's Multiple Range Test. Parameters measured were bacterial total count, meat pH, water holding capacity, cooking loss and tenderness (shear force). The results showed that the meat pH, water holding capacity, cooking loss were not significantly affected by storage time of frozen beef. While the bacterial total count and tenderness (shear force) significantly affected by storage time of frozen beef. The study concluded that the storage of frozen beef for 8 weeks did not reduce the physical characteristics of meat. Key words: frozen storage, the physical characteristics of meat, microbial populations.


The present invention relates to a multi-forging heat treatment process, in particular a low-temperature valve LF2 forging heat treatment process, process parameters: temperature rise rate of not more than 250 ℃ / h; normalizing a temperature of 900 deg.] C; quenching temperature 880 deg.] C, normalizing and quenching the holding time calculated as 1 hour / 25mm; forging furnace to the quenching time completely into the water for 30 seconds; the initial temperature controlled tempering temperature rise below 200 ℃, temperature rise rate of not higher than 150 ℃ / h, the tempering temperature is 630 ℃ , quenching and tempering holding time of the holding time of 1.5 to 2 times. After the heat treatment according to the present invention, the microstructure is visible, forging is tempered sorbite, and a uniform structure, no mesh ferrite and coarse grains phenomenon. Uniformly tempered sorbite and ensure the tensile properties to enhance the low temperature impact properties.


With the development of intelligent device and social media, the bulk of data on Internet has grown with high speed. There are so many important aspect in image processing, object detection is one of the international demanded research field. Multiple object detection is an important concept in object detection. In object detection extracting the features and handling the occlusion are two most important components. A Region-based Convolution Neural Network (R-CNN) has achieved great success in extracting the region based features which may used for extracting multiple regions from the images and Deformable Part Based Model (DPM) improve the ability for handling the occlusion. Occlusion handling is nothing but when multiple objects are near to each other that time some objects are not detected so this drawback will be handled by DPM. Existing method not performing well in the aspect of detecting multiple objects. In this paper R-CNN and DPM are to be integrated to detect multiple objects. By combining these two models we are able to notice every single object with high accuracy.


A control algorithm of tri-rotor aircraft using PID control and the effect of it in a tilt tri-rotor aircraft is proposed and observed in this paper.In the development of the control algorithm, a mathematical model consisting variables from three motors used and its tilting mechanism is obtained and referred to. A significant improvement is observed when the control algorithm is applied to the system in which the pitch overshoot is greatly reduced and approach to a constant zero.Tilt Tri-Rotor Unmanned Aerial Vehicle (TRUAV) is an aircraft that has three motors and does not allow pilot intervention in the management of the flight. There exist situations where the surrounding environment is not appropriate or even dangerous to a human being. Examples of such case is a war zone area, steep terrains, explosive area, or even during armed attacks.


1. Introduction and Background 2. Prudential Regulation and Supervision of Internet Banking 3. Online Privacy and E-Commerce 4. Data Protection and Internet Banking 5. Legal and Regulatory Aspects of E-Money 6. Account Aggregation: Legal and Regulatory Issues 7. Prudential Regulation and Supervision of Internet Banking in the United Kingdom 8. European Law Affecting Internet Banking 9. Data Protection and Internet Banking in the United Kingdom 10. Internet Banking in the United Kingdom: Distribution of Liability 11. Internet Banking in Australia: Law and Practice 12. Internet Banking in Malaysia: Law and Practice


Microfinance has generally been acclaimed as one way to reduce poverty through the provision of financial services targeting the previously "unbankable" poor. Persons with Disabilities (PWDs) are a ...


L andmark work from nearly 2 decades ago has had a major influence on our understanding of the benefit of increasing aerobic fitness for mitigating death in the apparent healthy and in those with established cardiovascular disease. Indeed, since the work of Myers et al, the research and clinical community has come to better appreciate the beneficial effects of long-term exercise, whereby increasingly greater exercise dosing confers a concomitant increase in exercise capacity. The past 2 decades have also generated intriguing data that high-intensity interval exercise, seemingly intended for only well-trained healthy individuals (as it facilitates high-volume exercise training in a reduced time window), is possible for, and may confer antiremodeling benefit in, patients with reduced ejection fraction after shortand long-term training. Exercise for patients with impaired systolic function is generally considered to be safe and improve patient symptoms and quality of life. But are there limits to exercise volume recommendations in patients with, or at risk for, left ventricular systolic dysfunction? Indeed, not all left ventricular dysfunction is the same, nor are the physiological benefits or exercise recommendations, and recent data further highlight the importance of appreciating exercise volume when considering exercise recommendations for some of these patients. In this issue of the Journal of the American Heart Association (JAHA), Skjølsvik et al present provocative data from their cross-sectional study that suggest greater exercise volume may potentiate cardiac remodeling in patients who are A/C lamin genotype positive. Specifically, the authors studied 69 well-characterized (see Table 1 in reference 11) diagnosed A/ C lamin genotype patients, aged 42 14 years (46% women), recruited from a single center. Of study patients, 41% (n=28) were probands and 59% (n=41) were family members. Exercise volume history was obtained via (structured) telephone interview or questionnaire (by mail) and quantified by allocating reported activities and sports participation >3 metabolic equivalents using the updated and highly referenced 2011 Compendium of Physical Activities. This cumulative lifetime exercise metric was computed from the age of 7 years to diagnosis/echocardiographic study, and the number of years over the lifetime exercise hours was standardized to account for age as a confounding variable. Those with a value above the group median of 4160 hours (interquartile range, 1041– 6924 hours) were considered active (n=34 patients; cumulative lifetime exercise=4.5 h/wk) versus those at or below the median, who were considered sedate (n=35 patients; cumulative lifetime exercise=0.8 h/wk). Cardiac assessment was performed by echocardiography in all patients, and cardiac magnetic resonance imaging was performed in a subset of patients. Conduction abnormalities, ventricular arrhythmias, and skeletal muscle function were also assessed. Active A/C lamin genotype–positive patients tended to be probands (53% of patients), displayed greater cardiac remodeling (ejection fraction, 43 13%; end-systolic volume, 79 39 mL; end-diastolic volume, 133 49 mL) compared with sedate patients (ejection fraction, 51 11%; end-systolic volume, 55 22 mL; end-diastolic volume, 111 25 mL), and subsequently were more frequently diagnosed with dilated cardiomyopathy (65% of patients); higher NT-proBNP (Nterminal pro-B-type natriuretic peptide) levels corroborated the echocardiographic remodeling evidence in active patients. Reduced left ventricular ejection fraction persisted in active patients with the standardized lifetime exercise analysis and when adjusted for age; higher frequency of dilated cardiomyopathy diagnosis also persisted in active patients when adjusted for age and sex. When the study group (n=69) was analyzed in tertiles of lifetime exercise, left ventricular ejection fraction decreased an absolute 4% per increasing cumulative lifetime exercise tertile, and this effect held true with standardized lifetime exercise analysis. Analysis of ageThe opinions expressed in this article are not necessarily those of the editors or of the American Heart Association. From the College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Correspondence to: Corey R. Tomczak, PhD, Russ Kisby Physical Activity and Health Promotion Laboratory, Integrative Cardiovascular Physiology Research Program, College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. E-mail: email@example.com J Am Heart Assoc. 2020;9:e015464. DOI: 10.1161/JAHA.119.015464. a 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.


This paper proposes a mixed-conduction-mode (MCM) current control for a grid-tied inverter operating in both continuous current mode (CCM) and discontinuous current mode (DCM) in order to minimize an interconnected inductor. In general, a low interconnected inductor value worsens disturbance suppression of current controller, and leads to an increase in grid current total harmonic distortion (THD). In DCM, the disturbance-to-current transfer function becomes nonlinear and the disturbances such as the dead time voltage error are effectively suppressed. Therefore, the grid-tied inverter operating in MCM can achieve a low grid current THD. However, another DCM nonlinearity occurs in the duty-to-current transfer function, which makes control gain characteristic in DCM completely different from that in CCM. There-fore, the DCM nonlinearity compensation is proposed by using duty at previous calculation. The validity of the proposed current control is confirmed with a 1-kW 100-kHz prototype. Even when using the interconnected inductor with a normalized impedance of 0.16%, the grid current THD is reduced from 14.8% to 2.9% at rated load compared to the conventional CCM control. Furthermore, the inductor volume is reduced by 77.0%, whereas the converter loss is reduced by 36.5%.


mdash; Digestive interaction study in a Rusitec device with binary mixtures of concentrate feeds. Estimation of nutritive value of compound feeds is based on the additivity of their ingredient values. This hypothesis was tested with binary blends in a Rusitec device. Results showed that when energy and protein were available at about the same time, positive interaction appeared after 24 h on dry matter degradation and on gas production during the first hours of incubation.


(57) [summary] [purpose] to reduce the cutting resistance at the time of counter boring of solid end mill with a bottom edge. [Configuration] wall 3a of the tool body 1 of the spiral groove 3,4, 4a And at the intersection ridgeline portion between the blade tip surface 2b, to form a nick 10 ... to be depressed from these intersection ridge line. These Nick 1 0 by, the inner peripheral end of the one of the bottom blade 7 from the outer peripheral edge 7a 7 The outer peripheral portion 11 is divided in two places between which leads to b, the central part 12 And subdivided into three parts of the inner peripheral portion 13. On the other hand of the bottom blade 8 is subdivided into two parts of the outer peripheral portion 14 and the inner peripheral portion 15 is divided in one place between leading to the inner peripheral end 8b from the outer peripheral edge 8a. [Effect] chip is the tool body 1, which is generated from the bottom edge 7, 8 Because it is subdivided into the radial direction, the chip is easily discharge resistance of the chip is reduced and divided.


Actinomycetes were characterized by production of various pigments on natural or synthetic media. These pigments usually described in terms of various shades of blue, red, rose, yellow, green, brown and black. Streptomyces is a major group in actinomycetes as blackish brown (melanin) pigment producer. The melanin production by Streptomyces species is the key feature for the classification of the Streptomyces group. The present study was focused on production and characterization of melanin producing Streptomyces. Soil samples were collected from the Shirala region Dist- Sangli. The total 14 Actinomycete isolates were obtained from soil by performing serial dilution technique and using Glycerol asparagine agar supplemented with Cycloheximide (100µg/ml). Morphology and spore chain arrangement of isolates were studied. Out of 14 isolates 12 were suspected belong to genus Streptomyces. The primary screening of 12 isolates for melanin production was carried out on peptone yeast extract iron agar. Two isolates such as Kd8 and Kd14 showed blackish brown diffusible pigment and these isolates were taken for secondary screening by using the tyrosine agar medium. The qualitative tests for pigment melanin were carried out by inoculating in tyrosine broth supplemented with traces of chloroform and incubating at 30 0 C for 48 hrs. Red color was reported in tyrosine broth indicated positive melanin production. On the basis of intensity of red color seen in the tyrosine broth Kd8 was selected for further study. Out of these isolates Kd8 isolate was identified on the basis of morphological, cultural, biochemical and 16S rRNA gene sequencing as Streptomyces bikiniensis. 0.8gm/100ml pigment was extracted from peptone yeast extract iron agar. The antibacterial activity of pigment extracted from Kd8 has been investigated. The pigment from isolate kd8 showed inhibitory zone against Escherichia coli, Staphylococcus aureus, Bacillus species and Salmonella typhi.


Abstract The paper presents the comparison of estimation results for spatial and spatiotemporal small area models. The study was carried out for income-related variables drawn from the Polish Household Budget Survey and explanatory variables from the Polish Local Data Bank for the years 2003-2013. The properties of EBLUPs (Empirical Best Linear Unbiased Predictors) based on spatiotemporal models, which utilize spatial correlation between neighbouring areas as well as historical data, were compared and contrasted with EBLUPs based on spatial models obtained separately for each year and with EBLUPs based on the Rao-Yu model. The computations were performed using sae, sae2 and spdep packages for R-project environment. In the case of sae package, the eblupFH, eblupSFH and the eblupSTFH functions were used for point estimation along with the mseFH, mseSFH and the pbmseSTFH functions for the MSE estimation, whereas the eblupRY function was applied for the purposes of sae2 package. The precision of direct estimators was guaranteed by the adoption of the Balanced Repeated Replication method. The results of the analysis demonstrate that a visible reduction of the estimation error was achieved for the implemented spatiotemporal small-area models, especially when significant spatial and time autocorrelations were observed. These results are even more valuable than those achieved by the means of the Rao-Yu model. In the computations, three author-defined functions were adopted, which not only enabled the author to perform the extract of random effects for spatial, spatiotemporal and Rao-Yu models, but also made it possible to obtain their decomposition with respect to spatial and temporal parts, thus creating a novel solution. The comparison was carried out using choropleth maps for spatial effects and distributions of temporal random effects for the considered years.


Equilibrium thermodynamics for porous media is considered with special emphasis on its basis in pore-scale thermodynamics. It is shown that porosity, the new purely macroscopic variable, enters the relations on the same footing as mass densities and the strain tensors. Biot's use of elastic energy potential, which lies at the foundation of his theory of poroelasticity, is examined in light of the results obtained here.


SUMMARY Over the past several decades a growing interest has emerged in the relationship between forest dependent communities and their use of non-timber forest resources (NTFR—i.e. berries, roots, barks). Motivated in large part by international concerns over the loss of biological and cultural diversity, efforts are now being made to conserve the world's remaining forests by repositioning NTFR to the forefront of the forest management process. Together with the Little Salmon Carmacks First Nation, we have undertaken an assessment that: 1) addresses the role of NTFR in fulfilling basic human necessities and well-being of community members, and 2) identifies the perceptual differences that exist among First Nation and non-First Nation community members regarding the security and future availability of forest resources. Based on our findings, we argue that if the true value of the forest is to be understood, and thus sustained, those involved in management must consider the full array of products and services the forest provides. Thus the conventional and over-simplified view that the forest is to provide primarily for commercial timber must be challenged in light of the multiplicity of values community members gain from forest use.


There is clearly a great need to utilize new technology in transportation in order to preserve competitiveness and maintain operational efficiency and effectiveness. Technology transfer is the medium through which new technology is introduced into an organization. It represents the missing link between research and operations; the bridge between theoretical knowledge and practical application of this knowledge. However, there is no doubt that technology whether a product of an agency's own research, or the product of others' research will not be successfully transferred through the mere delivery of reports. Report delivery is but one step in the transfer process, yet it is often mistakenly considered to signal the completion of the process. Experience has proven that sole reliance on report delivery to transfer research products is bound to yield unsuccessful transfer. Such passive mode of communication in which the human element is almost absent, has proven futile. To transfer technology effectively entails the dedication and commitment of specialists, time, and funds, alongside the delivery of reports. The purpose of the paper is to examine an organizational climate conducive to successful technology institutionalization in public transportation agencies. It places the spotlight on an often overlooked element in the transfer process: the human element. The emphasis on this element acknowledges the fact that active interaction between technology provider and receiver greatly facilitates a successful transfer.


Mutant gain‐of‐function (GOF) p53 acts as an epigenetic regulator to promote oncogenesis. Many cancers with a GOF mutation accumulate cholesterol and inhibition of cholesterol synthesis with statin treatment reverses some of the pro‐oncogenic properties of GOF p53. Our central hypothesis is that cholesterol accumulation alters lipid raft signaling, contributing to oncogenesis. To address the relationship between cholesterol and oncogenic properties, we measured cholesterol levels in a panel of cell lines and correlate these levels with both GOF p53 expression and oncogenic properties. To directly tie lipid raft composition to oncogenic properties, we utilized the SW13 cell line with two epigenetically distinct cell subtypes with differing oncogenic properties. The SW13‐ subtype has an epithelial morphology and is highly proliferative, while the SW13+ subtype has a mesenchymal‐like phenotype and a higher metastatic potential. When treated with histone deacetylase inhibitors (HDACi), SW13‐ cells appear to adopt a SW13+ phenotype. Therefore, we treated with both HDACi to control the subtype conversion and shRNA to knock‐down GOF p53 expression. This experimental approach allows the composition of raft fractions to be correlated to the oncogenic properties of each SW13 subtype, with and without GOF p53 expression.


Report discussing experiments done on expandable waxes of lignites to determine yields and properties from certain place in the United States.


Transient creep, an important deformation mechanism for polycrystalline ice at quasi‐static strain rates, is characterized by rate and temperature sensitivity, by isotropic and kinematic strain hardening, as well as by fabric and deformation‐induced anisotropy. A physically based constitutive model, using internal state variables, has been developed by Shyam Sunder and Wu (1989a, b) to describe the multiaxial behavior of ice undergoing transient creep. To solve boundary value problems using this constitutive theory requires the numerical time integration of a coupled set of stiff and highly nonlinear first‐order differential equations. A closed‐form Newton‐Raphson (tangent) formulation, in conjunction with the α‐method of integration, is developed to solve the constitutive equations. The fully consistent constitutive Jacobian matrix that is used to assemble the finite element tangent stiffness matrix is also established in closed form. This algorithm is implemented as a subroutine in the finite element pr...


Utilization of postpartum services is a major concern worldwide due to the great impact it has on infant and maternal mortality. Postpartum is defined as the first six weeks (42 days) following delivery of an infant. Care during this time is for the health and survival of the mother and the new born. Current estimation of Luanshya postpartum coverage of first postpartum care is 15% which is far below the recommended 80% by WHO. This study was therefore aimed at determining the factors associated with utilization of postpartum care services in Luanshya District. An analytical cross-sectional study was conducted on 187 mothers taking the children to the clinic aged between seven weeks to three months. Data was collected using questionnaires having both closed and open-ended questions. Stata 11 was used for statistical analysis of quantitative data. Qualitative data was explored for emerging themes and the frequency of themes were quantified. Chi-square was used to determine association of the variables. Logistic Regression analysis was used to ascertain which variables significantly affected the dependent variable. The findings from this study revealed that postpartum attendance was very low and stood at 27.8%. The major factors associated with low utilization of postpartum services were: postponement of sixth day postpartum care for Bacillus Calmette Guerin (BCG) (46%), feeling ill after delivery 29.4% and tradition 62.8%. This study demonstrated that there are gaps in the utilization of postpartum care services. Capacity and accessibility of health systems as well as cultural and religious practices are areas that affect postpartum care and hence should be worked on especially at community level. Such programs should include male involvement, influential family members such as grandmothers as well as traditional and religious leaders. Newborn babies should be vaccinated with BCG vaccine at birth so that the postpartum care appointments should be specifically for postpartum care.


Higher vocation education has its own characteristics in cultivation purposes, major setting and course setting, etc. It should have a new course, Math Predagogy in Higher Vocaton Schools.


Loughborough University (UK) and the University of Pau (France) have begun a joint research activity into a novel and non-invasive pulsed electric field food processing technique. As part of this programme, the reliable measurement of the intense transient electric fields generated in the near field of an antenna immersed in water is essential.


The onset of gate-drain avalanche imposes an important fundamental constraint on the drain voltage swing, and hence, on the output power of GaAs FET's. In this paper we show that recognition of the role of surface depletion and proper attention to channel design can yield avalanche voltage factors of 2-3 above bulk values. The appropriate design strategy is minimization of the undepleted epitaxial charge per unit area (Qu) between gate and drain, which, in turn, dictates a gate-notch depth approximately equal to the surface zero-bias depletion depth. A simple lateral spreading model is proposed which predicts thatV_{L} \sim 50Q\min{u}\max{-1}, where VLis the gate-drain avalanche voltage and Quis measured in units of 1012electrons/cm2. This prediction is supported by a large body of experimental dc and pulse data, although considerable scatter is observed which we have attributed to epi charge nonuniformities, premature avalanche at the rough edges of AI gates formed by a liftoff process, and surface charging variations associated with dielectric passivation. The observed dependence of VLon epi charge rather than on doping level, as predicted for bulk avalanche, provides convincing evidence for nonbulk two-dimensional avalanche in the thin-film (Q_{u} < 2.3) FET geometry. In thick films (Q_{u} > 2.6), on the other hand, it is found that the bulk avalanche predictions are reasonably accurate. In terms of saturated epi current Is, the bulk regime corresponds toI_{s} > 450mA/mm and the lateral spreading (thin-film) regime toI_{s} < 400mA/mm. Finally, we have found that gate-drain avalanche is the major cause of output saturation as a function of drain potential in power GaAs FET's.


NarE is an arginine‐specific mono‐ADP‐ribosyltransferase identified in Neisseria meningitidis that requires the presence of iron in a structured cluster for its enzymatic activities. In this study, we show that NarE can perform auto‐ADP‐ribosylation. This automodification occurred in a time‐ and NAD‐concentration‐dependent manner; was inhibited by novobiocin, an ADP‐ribosyltransferase inhibitor; and did not occur when NarE was heat inactivated. No reduction in incorporation was evidenced in the presence of high concentrations of ATP, GTP, ADP‐ribose, or nicotinamide, which inhibits NAD‐glycohydrolase, impeding the formation of free ADP‐ribose. Based on the electrophoretic profile of NarE on auto‐ADP‐ribosylation and on the results of mutagenesis and mass spectrometry analysis, the auto‐ADP‐ribosylation appeared to be restricted to the addition of a single ADP‐ribose. Chemical stability experiments showed that the ADP‐ribosyl linkage was sensitive to hydroxylamine, which breaks ADP‐ribose‐arginine bonds. Site‐directed mutagenesis suggested that the auto‐ADP‐ribosylation site occurred preferentially on the R7 residue, which is located in the region I of the ADP‐ribosyltransferase family. After auto‐ADP‐ribosylation, NarE showed a reduction in ADP‐ribosyltransferase activity, while NAD‐glycohydrolase activity was increased. Overall, our findings provide evidence for a novel intramolecular mechanism used by NarE to regulate its enzymatic activities.—Picchianti, M., Del Vecchio, M., Di Marcello, F., Biagini, M., Veggi, D., Norais N., Rappuoli, R., Pizza, M., Balducci, E., Auto ADP‐ribosylation of NarE, a Neisseria meningitidis ADP‐ribosyltransferase, regulates its catalytic activities. FASEB J. 27, 4723–4730 (2013). www.fasebj.org


In this paper, the effect of geometry and impedance on the acoustic behavior of wall and
lined cylindrical ducts is investigated using a numerical model which enables one to compute
the reflection and the transmission coefficients of such ducts using the multimodal scattering
matrix. From this matrix, the acoustic power attenuation is deduced. By using these tools,
the effect of duct diameter increase and duct diameter decrease of the wall or lined duct
section is studied. The numerical results are obtained for two configurations of wall and
lined ducts. Numerical coefficients of transmission and reflection as well as the acoustic
power attenuation show the relative influence of each type of variation.


The trade war between the USA and Asia (and the EU as well) involving steel protection shows how protectionism has mainly covered the inefficiency of the US steel industry, which has never accepted the idea of restructuring. In line with what economic theory suggests, the costs for the US economy have been larger than the benefits. However, helping the steel industry - which is concentrated in few key States - has probably helped in a decisive way G.W. Bush to gain a second mandate.


Alginate fibers are well established as primary wound dressings, given their well-known sodium/calcium ion exchange ability at the wound surface coupled with their good liquid absorption characteristics. Chitosan, the deacetylated form of chitin is also well known for its hemostatic, antimicrobial, and wound-healing properties. Unique combination of these polysaccharides to form a new generic fiber, known as alchite fibers, has been developed in an earlier work. This article reports on the antimicrobial properties of a range of alchite fibers produced from four different types of hydrolyzed chitosans and two brands of sodium alginate. The article discusses different methods of antimicrobial detection including: submerged fiber technique, zone of inhibition, dilution plating, and spectrophotometric analysis at 600 nm when tested against common skin microflora, i.e., Staphylococcus aureus, Staphylococcus epidermidis, and Micrococcus luteus. This study concludes that while most of the alchite fiber samples have certain degree of antimicrobial properties, some have higher antimicrobial properties than others. The study has also shown that quantitative presence of chitosan within an alchite fiber may not necessarily be the reason for good antimicrobial properties. Factors such as chitosan source, degree of deacetylation, molecular weight, and action of hydrolysis may also affect antimicrobial properties. These findings are most important in endorsing the development of the alchite fibers for wound dressings.


The article presents preliminary assessment of the accident scale, level of its radiation effect on the population and response of national authorities of various countries for the population radiation protection provisions. High levels of the environmental radioactive contamination demanded the application of complex measures for the radiation protection of the population from adjacent territories of Japan. Radionuclides from the region of damaged NPP can get to the other countries by means of the long-distant air and sea water mass transfer. Specific activity of cesium radionuclides in the sea biota can reach the level recommended by the Codex Alimentarius Commission as the safe level for the international trade or exceed it. Significant radioactive contamination of the territories of other countries resulting from the «Fukushima-I» NPP accident did not occur. Many world countries applied measures of the Japanese food products import control on the base of the radiation monitoring data. These prohibitions are consequently remitted following the radiation situation improvement.


Outside expertise in workforce planning should be brought into the NHS to help improve its record on matching staff numbers to patients' needs, MPs have been told.

Independent health economists could help the NHS make its workforce planning more accurate, the parliamentary health select committee was told last week in the latest evidence session of its inquiry into workforce planning.

Susan Hodgetts, chief executive of the Institute of Healthcare Management, the professional body for health service managers, said health economists would give workforce planning a "reality check."

In prepared written evidence, she said, "There is a case for workforce …


A novel quantitative nano+micro-tribometer with integrated nanoindenter, SPM and optical microscope imaging has been used to characterize mechanical properties of Cu coated Si wafers at various test stages. A 2D Finite Element Model was developed to study changes on workhardened contacts assessed via nanoindentation experiments.Copyright © 2005 by ASME


Among the many predators of the spinning mites found on citrus and avocado trees in southern California, the staphylinid beetle, Oligota oviformis Casey[2][1], probably ranks third in importance, being outranked not only in effectiveness but also in numbers by predatory mites and Stethorus species. These very tiny staphylinid beetles are occasionally found in large numbers, and in such cases they contribute materially to the reduction of mite infestations. As will be shown later, the rather sporadic distribution of the insect is associated with both cultural practices and soil condition.

 [1]: #fn-2


In the article the basic directions of the prevention of child injuries on the roads. Children's injuries as a result of road and transport incidents (road accident) is on the first place among the causes of injuries and causes of deaths for children from 4 to 14 years. The only constant work of all participants of the movement for the protection of our rising generation can give a substantial and stable result in the prevention of child injuries from road accidents.


Pseudo-potentials for Rb and Cs have been generated that represent the effects of core-valence correlation by a polarisation potential and that reproduce spin-orbit splittings in the atoms to within 10-7 au(<or approximately=1%). These potentials were used to calculate the potential curves of the X 2 Sigma g1/2, 1 2 Sigma u1/2, and 1 2 Pi u3/2 states of Rb2+ and Cs2+. In the latter case, experimental data exist for the spin-orbit splitting of the Pi u states. The calculated and the measured values agree excellently.


The present work was developed to show the study of electrical protection of turbogenerators. The interest in the development of the work arose due to the relevance and complexity of the proposed theme. Turbogenerators are synchronous generators developed for thermoelectric power plants and can be applied to steam or gas turbines. Synchronous generators are elements of great importance within a power system and their failure or unplanned shutdown can cause serious instability in the electrical system if there is no other source of generation available. Because they are subject to various types of defects and failures, they have an elaborate protection system composed of protection relays, auxiliary relays and accessories. The main purpose of this protection system is to maintain a high level of continuity of service and, in the event of intolerable conditions, to minimize the size and time of disturbances. Its secondary function is to indicate where the fault occurred and the type of fault, facilitating the diagnosis and reestablishment of the systems involved. In this work the main protections applicable to turbogenerators are discussed, the theoretical bases for their understanding and a case study as validation of the developed content.


Abstract Quantum mechanical lineshapes of collision-induced absorption (CIA) at room temperature are computed for gaseous molecular oxygen using theoretical values for induced dipole moments and new isotropic interatomic potential as input. Comparison with measured spectra of the rototranslational collision-induced absorption shows good agreement over the full range of frequencies. Empirical models of the dipole moment which reproduce the experimental spectra and the first two spectral moments more closely than the fundamental theory are also given. The quality of the present potential has been checked by comparing between calculated and experimental thermo-physical and transport properties over a wide temperature range, which are found to be in good agreement.


This study has as general objective a proposal of marketing actions for Panificadora Vo Maris. The methodological approach used is qualitative, being a basic, descriptive and bibliographic research, through a case study. An analysis of Facebook page evaluations was performed to identify customer satisfaction. As a result, company strengths and weaknesses were identified through the Swot analysis. As a result, the strengths highlighted are the quality of products and services, personalized service, clean environment, diversity of options, differentiated brand and innovation in the region. Already, weaknesses: high operating cost, lack of qualified personnel, perishable products, new competitors, increased regulation and economic crisis. From this information a proposal of marketing actions was developed using the methodology of OKRs - Key Results Objectives. As for the proposed marketing actions are: partnerships with companies, weekly promotions, announcements in communication vehicles and promotions on commemorative days. Thus, all the results presented in the elaboration of the marketing actions demonstrate to the organization opportunities for more assertive decision making, making it possible to reach the goals and objectives traced by it.


The article shows that in the austenite after hot deformation while finely substructure exists in the form of polygonal boundaries, provides the basis for heterogeneous nucleation of grains hypoeutectoid ferrite.


In order to use a microphone array to locate speech signals preferably and obtain higher positioning accuracy,the constructive method and performance characteristics of TDOA(Time-Delay of Arrival)algorithm are studied,reasons and environment of causing errors in locating processing are analyzed,and some methods that can reduce or eliminate the errors are proposed.Using the time-delays of signals from the same speech signal source between any two microphones in the array and the relationships within the time-delays,the locating results can be simulated on computers.The solutions proposed can improve the locating accuracy greatly and increase the utilization rate of the TDOA algorithm in practical application.


Importance Septic arthritis of the native knee joint is the most common bacterial joint infection. The management involves prompt surgical debridement and joint irrigation by arthroscopy or arthrotomy. This is the first systematic review and meta-analysis to compare arthroscopic debridement with arthrotomy for septic arthritis of native knee joint. Objective The purpose of this systematic review and meta-analysis is to compare re-operation rates, length of inpatient hospital stay (LOS) and functional outcome between arthroscopy and arthrotomy in the treatment of acute septic arthritis of the native knee joint. Evidence review This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Embase and Cochrane Central Register of Controlled Trials databases were searched from database inception to 31 May 2019. All original studies that compared re-operation rates and LOS between arthroscopy and arthrotomy for septic arthritis of knee were included. The research question and eligibility criteria were established a priori. Pertinent data were extracted and random-effects model was used to pool the data where possible. Findings A total of seven studies with 1089 knees were included, of which 723 underwent arthroscopic surgery and 366 knees underwent arthrotomy. The relative risk of re-operation was significantly lower in the arthroscopy group with a pooled relative risk of 0.69 (95% CI 0.56 to 0.86; p=0.0006). All studies reported shorter LOS and one study reported better functional outcomes in the arthroscopy group as compared with arthrotomy. However, the data could not be quantitatively synthesised due to variation in reporting among the studies included. Conclusions and relevance Based on the available evidence, we conclude that arthroscopy for the treatment of septic arthritis of the knee results in a lower re-operation rate than arthrotomy. It cannot be concluded whether arthroscopic treatment results in shorter LOS or better functional outcome as compared with arthrotomy. Level of evidence IV


This work quantifies the damage caused by moisture in a metal coating system under extreme weather- ing conditions, using Variable Radius Roll Adhesion Test (VaRRAT). Interfacial toughness (adhesion energy) between the metal oxide and the polymer in painted steel panels, studied by using VaRRAT, is observed to fall with increas- ing temperature and time of exposure to moisture. Possible cause for irreversible loss in adhesion energy in the paint system is attributed to the sorption of free water at the metal oxide-polymer interface. Different failure responses were observed in two different paint-metal systems. Adsorption or diffusion in the Henry's mode is rate controlling in green paints as indicated by the low activation energy of 12 kJ mol 1 . The white samples showed a high activation energy of 30 kJ mol 1 , indicating a mixed process of diffusion as well as chemical to be rate determining. Different paint/ binder ratios are responsible for the different responses of these samples. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 99: 2052-2061, 2006


The different aspects of building energy system operations can be analyzed from historic data that are captured by various sensors during building operation. The analysis of these different features helps to understand the operational behavior of the building's energy systems, which can contribute to plan efficient use of energy in buildings. One of the major information that can help in proper planning of energy consumption is to have a method that can automatically detect the occupancy in buildings with the different sensor data used for monitoring. The data of an air ventilation system, which is responsible for maintaining appropriate indoor air quality, is used for this research. This paper presents a method that uses the K-means clustering algorithm for automatic detection of occupants using air quality data of the ventilation system. The proposed method has been applied on real monitoring data and results are discussed in detail, showing a good identification of the detected occupancy with the advantage of saving the costs for additional sensor equipment.