The effects of an M&A process on corporate organisation. Foreign direct investments worldwide and in Italy. An empirical analysis. A comparison with foreign direct investments made by Italian firms.


The composition of the microbiota of the Aro cheese marketed in the municipality of Teotitlan de Flores Magon, Oaxaca, Mexico, was determined, quantifying the aerobic mesophilic bacteria, psychrophilic bacteria, total coliforms, Escherichia coli, Staphylococcus aureus, Salmonella, Enterococcus, Streptococcus, lactic acid bacteria, moulds and yeasts. The results showed that the Aro cheese contained pathogenic and spoilage microorganisms as well as those of industrial importance. None of the samples analysed complied with NOM-243-SSA1-2010. Thus this cheese could transmit foodborne illnesses, due to its high content of E. coli, Staphylococcus aureus and Salmonella. The shelf life of the cheese could also be affected causing economic losses to the producers. On the other hand, microorganisms of industrial importance can be obtained (Lactobacillus and Streptococcus). It is necessary to implement quality assurance systems to guarantee the production of innocuous cheeses.


Avian embryos and neonates acquire passive immunity by transferring maternal immunoglobulins from serum to egg yolk. Despite being a convenient source of antibodies, egg yolk immunoglobulins (IgY) from immunized hens have so far received scant attention in research. Here we report the generation and rapid isolation of IgY from the egg yolk of hens immunized against the α subunit of the human hypoxia‐inducible factor 1 (HIF‐1α). Anti‐HIF‐1α IgY antibodies were affinity purified and tested for their performance in various applications. Abundant HIF‐1α protein was detected by Western blot analysis in nuclear extracts derived from hypoxic cells of human, mouse, monkey, swine, and dog origin whereas in hypoxic quail and frog cells, the HIF‐1α signal was weak or absent, respectively. In electro‐phoretic mobility shift assays, affinity‐purified IgY antibody was shown to recognize the native HIF‐1 (but not the related HIF‐2) complex that specifically binds an oligonucleotide containing the HIF‐1 DNAbinding site. Furthermore, IgY antibody immunoprecipitated HIF‐1α from hypoxic cell extracts. Immunofluorescence experiments using IgY antibody allowed the detection of HIF‐1α in the nucleus of hypoxic COS‐7 cells. For comparison, the application of a mouse monoclonal antibody raised against the identical HIF‐1 α fragment was more restricted. Because chicken housing is inexpensive, egg collection is noninvasive, isolation and affinity purification of IgY antibodies are fast and simple, and the applicability of IgY is widespread, immunization of hens represents an excellent alternative for the generation of polyclonal antibodies. —Camenisch, G., Tini, M., Chilov, D., Kvietikova, I., Srinivas, V., Caro, J., Spielmann, P., Wenger, R. H., Gassmann, M. General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia‐inducible factor 1α. FASEB J. 13, 81–88 (1999)


This study is carried out to identify those factors that affect the adoption of sustainable agriculture among sugar beet growers in South Khorasan. Its statistical society constituted of beet growers in South Khorasan that are over 6220 people, which between them sample of 200 people have been studied by stratified random sampling method. The field data was collected using a researcher made questionnaire. This study data were analyzed using spss software and in two descriptive and inferential parts. Findings from descriptive analyzes showed that the adoption of sustainable agriculture in this region is in an average level. In addition, the findings of the correlation analysis showed that there is a significant and positive relationship between education level, type of farming systems, type of ownership, type of agriculture, type of used seed, the total amount of cultivated land, land under cultivation of sugar beet, social participation, yield and income, source of income other than agriculture, the promoters calls, resolved crops issues, attending training classes - promotion, knowledge, attitude and adoption of sustainable agriculture, and there is a significant and negative relationship between age, experience in agriculture and adoption of sustainable agriculture. Regression analysis also showed that four variables: attitudes, knowledge, age, and the total amount of cultivated land is explained about 93/5% of the variability of adoption dependent variable.


Mobile environment has revolutionized the health field. This fact and the rise of mobile technology have led to improve processes of care. In this paper, we present a practical application of BSC (balance scorecard) for Management of clinical incidents in ICT services through mobile devices in health organization. The objective of building of system is to integrate with main system of organization, for management of critical incident in ICT department of hospital and health centre. To do this, we have analysed and evaluated of process to management of incident that allow us to show the management information of way practical and we have applicated a real case. Results suggest that the integration of Balanced Scorecard helps with decision-making tasks because they allow decreasing response times and improving company management. In conclusion, make users satisfaction grow, objective sought by health companies


Background: Keeping in view the importance of natural plant products, bioactivity‑guided isolation of phytoconstituents was attempted from Lawsonia inermis L. Materials and Methods: Various polar and non‑polar extract/fractions were isolated and evaluated for the genotoxic and antigenotoxic potential against mutagens viz., 4‑nitroquinoline‑1‑oxide and nitrofurantoin in SOS chromotest using Escherichia coli PQ37 tester strain and against H2O2 in DNA protection assay. In order to decipher mode of action, antioxidant activity was evaluated using different assays. The extract/fractions were also investigated for their antiproliferative potential against PC‑3 and Colo 205 cancer cell lines. Major polyphenolic constituents were identified using high-performance liquid chromatography (HPLC) technique. Results: All the extract/fractions except Hex‑Li significantly decreased the SOS‑inducing potency of both the mutagens. In various in vitro assays, the polar fractions exhibited marked antioxidant activity. HPLC analysis of the extract/fractions showed that gallic acid, catechin, chlorogenic acid, epicatechin, rutin, ellagic acid, quercetin and kaempferol are the major constituents. The marked antigenotoxic activity of extract/fractions may be attributed to the polyphenolic compounds. The fractions viz., Hex‑Li and CHCl3‑LI were found to be highly cytotoxic against Colo‑205 cancer cell line. Conclusions: This is the first report of antigenotoxic and anticancer activities of Lawsonia inermis L. phytoconstituents. The antiradical potency of these extract/fractions may be responsible for the above activities. Key words: 4‑Nitroquinoline‑1‑oxide, antioxidant activity, cancer cell lines, nitrofurantoin, SOS chromotest


Immune checkpoint inhibitors open a new door for tumor immunotherapy, but it should not be ignored that some tumor patients are still insensitive to this kind of therapy. The purpose of this study is to analyze the prognostic value of STK11 mutations in metastatic cancer patients treated with ICIs. Information regarding somatic gene mutations of STK11 and patients' survival time in advanced cancer patients receiving ICIs treatment was downloaded from the cbioportal database. The prognostic value of STK11 gene mutation was analyzed by Log-rank test and multivariate Cox proportional hazards regression analysis. The somatic mutation frequencies of STK11 among all patients were 6.14%, and STK11 gene mutations were mainly distributed in patients with non-small cell lung cancer. The results showed STK11 gene mutation status was associated with shorter survival time, the hazard ratio is1.746 (P <0.0001). The somatic mutations of STK11 were also associated with shorter overall survival in NSCLC patients (P = 0.017). Multivariate Cox proportional hazards regression analysis showed STK11 gene mutation was significantly associated with overall survival (HR= 1.567, 95%CI: 1.209-2.029, P= 0.001). The results of this study suggested that STK11 gene mutation could be used as a negative prognostic marker in metastatic cancer patients receiving ICIs treatment.


The impact of stochastically perturbing the terminal velocities of hydrometeors on convective-scale ensemble forecasts of precipitation was examined. An idealized supercell storm case was first used to determine the terminal velocity error characteristics for a one-moment microphysics scheme in terms of the terminal velocities from a two-moment scheme. Two real cases were employed to evaluate the forecast skills resulting from perturbing the terminal velocities with real data. The results indicated that the one-moment scheme produced terminal velocities that were approximately three times higher than those of the two-moment scheme for snow and hail, which often resulted in overpredictions of hourly precipitation and areal accumulated precipitation. Therefore, stochastically perturbing the terminal velocities according to their error characteristics matched the observed hourly precipitation and areal accumulated precipitation better than the symmetrical perturbations. For the two-moment scheme, the symmetrical perturbations of the terminal velocities tended to produce lower falling speeds of precipitation hydrometeors; therefore, more light rain was produced. Compared to the unperturbed two-moment scheme, symmetrically perturbing the terminal velocities resulted in smaller precipitation errors when precipitation was overestimated but comparable or slightly larger precipitation errors when precipitation was underestimated. This work demonstrates the sensitivity of precipitation ensemble forecasts to terminal velocity perturbations and the potential benefits of adopting these perturbations; however, whether the perturbations actually result in significant improvements in precipitation forecast skill needs further study.


With policy-based networking, it is possible to define network policies based on user and application oriented business/service level objectives and to distribute the corresponding policy decisions/intelligence across the network consistently. One such policy framework is jointly defined, as an evolving industry standard, by the Internet Engineering Task Force (IETF) Working Groups (Policy Framework (PF) and Resource Allocation Protocol (RAP)) and the Directory Enabled Networks (DEN) Industry Group. Management and control, in the IETF framework, deploys a centralized client-server approach which has severe drawbacks with regard to scalability, flexibility and performance. The IETF framework does not scale well to support policy-based management of multi-domain networks. Policy rules, in the IETF framework, are static and have fixed semantics making rules difficult to adapt to change. This paper presents a new framework that overcomes these limitations. The paper describes an architecture that deploys trusted, intelligent and mobile agents in an open programmable networking framework. Policies, in the new framework, are extended to be dynamic and can be installed at network as well as at node (device) level. A policy rule is defined by a single event specification, an executable condition function and executable action function. Rules and interactions among agents are defined in XML notations and schemata. The use of XML for policy representation leads to semantically enriched policy components addressing a variety of functional requirements to a policy framework designed for an open communications market. An illustrative real-world example is also presented in the paper.


Because of enlarging enrollment of postgraduate students and market economy,the advantage of students' employment is not so obvious.This thesis analyses the influences of uncontrollable factors on employment,such as,educational background,age,gender and major.The paper tries to advance solutions,which could be a reference for postgraduate students' employment.


Sea area along Fengxian District is located in the northern Hangzhou Bay,where the migratory fish such as Coilia mystus,Pampus argenteus,etc must pass through for spawning and feeding migration. Set net is the only way for fishing in this sea area,so studying on the variety of yield and yield value from a set net fishing boat is very helpful to evaluate the current fishing income on the sea along Fengxian District. As no study has been carried out investigating the variation of yield value and value per unit effort( VPUE) from set net fishing boat on the sea along Fengxian District,the methods of curve estimation and cluster analysis were applied in this study to evaluate the variation of yield value and VPUE,which may be helpful to find out the relationship among yield,yield value and VPUE from a set net fishing boat in Fengxian District( from May 2009 to October 2012). The results indicated that yield value and VPUE from set net fishing boat increased year by year,yield value and VPUE in 2009 was 205. 7 thousand yuan and 44. 59 yuan per net respectively, and in 2012 increased to 313. 5 thousand yuan and 61. 98 yuan per net respectively. Yield and VPUE had no significant correlation( P = 0. 501 0. 05),but yield value and VPUE had significant correlation( P = 0. 008 0. 05),and the relationship between yield value and VPUE can be expressed as following equation: y = 33. 812lnx + 5. 3808. In seasonal variation of VPUE,there was no significant correlation between spring and summer( P = 0. 093 0. 05),there was also no significant correlation between spring and autumn( P = 0. 165 0. 05),but there was significant correlation between summer and autumn( P = 0. 008 0. 05). The research showed that it was inadvisable for fishman to pursue profits by maximizing total catch and they should increase yield and proportion of commercial fishes,which can not only increase fishing income,but also promote protection of juvenile fish and recovery of fishery resources.


The preparation of a meso-thioacetoxyporphyrin by ring synthesis from a dipyrrylthione is described together with the reaction of thiocyanogen with octaethylporphyrin and coproporphyrin 11 to give meso-thiocyanatoporphyrins. Attempts to produce meso-mercaptoporphyrins by hydrolysis of either meso-thioacetoxy- or meso-thiocyanato-porphyrins failed. Instead the corresponding disulfides were produced and the properties of this latter group are described.


The title compound, C30H18O2P2, is a chiral biphospbine ligand. Itscrystal structure was determined by X-ray diffraction analysis. The crystal is or-thorhombic I space group, P212121 1 greement factor for 2326 independent reflections with (I)- In the molecu1e, two diphenylphosphino groups are in the same side of two rigidtetrahydrofuran rings and point out from each other resulting in the non-chelate charac-ter of this bidentate ligand, the title compound.


We calculate the next-to-leading-order cross section for the inclusive production of B mesons in pp collisions in the general-mass variable-flavor-number scheme, an approach which takes into account the finite mass of the b quarks. We use realistic evolved non-perturbative fragmentation functions obtained from fits to e+e- data and compare results for the transverse-momentum and rapidity distributions at a center-of-mass energy of 7 TeV with recent data from the CMS Collaboration. We find good agreement, in particular at large values of pT.


The the tels que l'organisation du travail, le paiement par les primes à la production, le travail temporaire. Les deux entreprises, sur le territoire, génèrent le développement de savoirs et de compétences qui se transmettent de génération en génération. ils représentent la seule source stable de revenus pour les personnes, mais les amènent à s'engager pour leur santé. Fishing activity produces identification and knowledge of the trade in a given context. In this article two case studies are presented : 1) Women workers in the process of transformation of oysters ; 2) Fish unloading operators, in another fishing company. Both situations are analyzed from the model centered on the person in activity, which were carried out through the ergonomic intervention scheme, presenting the following stages of the intervention : analysis of the demand ; pre-diagnosis ; and proposal of the intervention. The activities studied show the inequities linked to the determinants of the activity, such as the organization of work, payment through production bonuses, temporary work. Both companies, in the territory, generate the development of knowledge and skills that are transmitted in generations. they represent the only stable source of income for people, but leading them to make a commitment to their health


Objective To investigate significance of the expressions and correlation of CD44 v6 and MMP-9 in PSTT.Methods The expression of CD44 v6 and MMP-9 protein were detected in 30 specimens normal placetal villi and 15 specimens of PSTT by immunohistochemistry(SABC method).Results In nomal placental villus,benign PSTT and malignant PSTT,The expression rate of CD44 v6 was 3.3%,30.30% and 100% respectively.The positive rate of MMP-9 protein was 6.7%,38.5% and 100% respectively.Conclusion The expressions of CD44v6 and MMP-9 are correlated to invasion and metastasis of PSTT and they can be as markers to predict metastasis and invasion and prognosis of PSTT.


The effects of rotor assembly with helical lobe and grooved helical lobe on heat transfer,flow friction and thermal performance characteristics in a round tube were experimentally investigated.The results showed that both heat transfer rate and friction factor associated with rotor assembly were consistently higher than those without rotor assembly.The Nusselt number with helical lobe rotor assembly and grooved helical lobe rotor assembly increased 1.06—1.26 and 1.03—1.15 times than that in the plain tube respectively.The friction factor with helical lobe rotor assembly and grooved helical lobe rotor assembly increased 60%—68% and 36%—51% than that in the plain tube respectively.Considering both heat transfer rate and friction factor,the performance evaluation criteria(PEC)of two kinds of rotors were compared,the result indicated that grooved helical lobe rotor assembly had a better thermal performance characteristic.


Nowadays, how to reduce carbon emissions is a hot issue in environmental economics research, and countries around the world are having extensive discussions on their respective carbon emission obligations. The embodied carbon contained in international trade plays a crucial role in controlling pollutant emissions but it is often overlooked, resulting in problems such as carbon displacement and avoidance of responsibility for pollutant emissions. Based on the Social Sciences Citation Index (SSCI) and Science Citation Index-Expanded (SCI-E) database, this paper adopts a bibliometric method to summarize 626 papers from 1994 to 2023 in six aspects, including the number of the literature, the literature citations, research region, journal, author, and research discipline. Meanwhile, the research method and model used in the collected papers are classified and reviewed. Then, this study briefly outlines the current status of embodied carbon emissions and the international pollutant identification laws and analyzes the shortcomings of existing research and the rationality of responsibility identification principles. Finally, we propose future research hotspots by combining carbon neutrality and carbon trading theory.


OBJECTIVE
To compare the recovery of cornea endothelia after phacoemulsification (phaco) with anterior chamber irrigation at different temperatures.

STUDY DESIGN
A between-group design was used.

PARTICIPANTS
Thirty-eight patients with cataract.

METHODS
Phaco was done on 40 eyes in these patients with exactly the same procedure except for the temperature of the anterior chamber: cryoirrigation at 12 masculine C for group 1 and at room temperature (25 masculine C) for group 2, 20 eyes in each group, randomly distributed. The cornea edema, keratic precipitate (KP), and anterior chamber flare were observed with micro-slit lamp and graded on a 4-point scale at 1, 3, and 7 days after surgery and compared between groups.

RESULTS
The corneas in group 1 were found to be clearer than those in group 2 at 1 and 3 days after surgery. The difference was statistically significant (p < 0.05) in favour of group 1, suggesting a lighter reaction of cornea endothelia and a quicker recovery in group 1 after the surgery with cryoirrigation. Corresponding recovery in group 2 was found to occur latterly between day 3 and day 7. However, the recovery in both groups was complete, yielding no difference between groups, at day 7 after surgery. In addition, no significant difference was found in Tyndall phenomenon and KP between groups.

CONCLUSIONS
Cryoirrigation during phaco could reduce postoperative cornea edema and promote recovery. The result advocates the use of cryoirrigation in clinic.


UNLABELLED
Multiple intracranial meningiomas (MIM) are a rare pathology when not associated with neurofibromatosis. The prevalence rate of those tumors varied from 2.3 to 8.9% of all intracranial meningiomas.

OBJECTIVE
To present, analyze and discuss the cases of seven patients diagnosed with multiple intracranial meningiomas, describing their clinical and histological characteristics, as well as their biological behavior.

METHOD
The patients records, surgical descriptions, imaging studies and the histopathological exams were retrospectively reviewed. This is the largest series of MIM publisted in Brazil.

RESULTS
This sample consists of five women and two men. The age varied from 42 to 84 (average 53.8). Twenty-two meningiomas were identified and varied from 1.5 to 192 cm(3), with an 62.8 cm(3) average volume. The number of procedures varied from 1 to 5 per patient. No surgical death occurred in this series.

CONCLUSION
Despite the multiplicity of tumors, number of recurrences, the new tumors, repeated operations and re-operations, radiotherapy and a number of postoperative complications, the patients experienced a long survival in conjunction with a fairly good quality of life.


The media in Ghana has traditionally played agenda setting and gate keeping roles. However, new media threatens this role, and this qualitative study explores this issue from the perspective of some industry players and academics. It established that new media presents new culture of open gates and diminished agenda setting role of traditional media.


The present patent application, comprises a linear transconductor having at least one input unit and parts of at least one output, a linear transconductor is a differential amplifier having a plurality of transistors and a plurality of input portions, which is the difference between the input signal amplifier, said differential amplifier; A cascode circuit having a plurality of transistors, in common with a plurality of transistors of the reverse blocking between the input and output of the linear transconductor being operatively connected to a differential amplifier, the stack on at least one transistor of the differential amplifier gate a cascode the cascode circuit, is improved by mounting a plurality of at least one transistor of the transistor of the circuit by a decoupling unit input and output of the linear transconductor; The active load having a cascode circuit comprising: a plurality of transistors operatively connected between the power supply voltage; And an active load, the cascode circuit and an auxiliary device operatively connected to the connection between the ground. A linear transconductor, a differential amplifier, a cascode circuit,


We deposited a lead zirconate titanete (PZT) polycrystalline film on a titanium substrate by the hydrothermal method and fabricated a transducer using the PZT film for use as an ultrasound probe. A 10 MHz miniature one-dimensional-array medical ultrasound probe containing the PZT film was developed. After sputtering titanium on the surface of a hydroxyapatite substrate, the titanium film on the substrate was etched by the photolithography to form a one-dimensional titanium film electrode array. We could thus fabricate a miniature one-dimensional-array ultrasound probe by the hydrothermal method. Transmitted ultrasound pulses from a 10 MHz commercial ultrasound probe were received by the newly fabricated one-dimensional-array ultrasound probe. The fabrication process of the probe and the results of experiments on receiving waveforms were reported in this paper.


The Web-based Mathematics Education (WME) framework aims to create a Web for mathematics education where education content and support services are interoperable on the Web and can be created, deployed, and maintained on a distributed basis. To test the feasibility, practicality, and effectiveness of WME as a way to enhance mathematics education in schools, a pilot project at Kimpton Middle School (Munroe Falls, Ohio) has been launched. The pilot generated positive feedback from students and teachers. Described are the WME approach, the pilot website, teaching experiments with 7th grade students, lessons learned, and future plans.


Through studying the phosphorus adsorption isotherm curve of sediment with different particle sizes of Wuliangsuhai Lake,its phosphorus adsorption processes was studied.The result shows that both the Langmuir model and Freundlich models can better fit the phosphorus adsorption isothermal curve of the sediments with different particles size level of Wuliangsuhai Lake.The order of adsorption quantity from large to small is 63 μm,63~125 μm,125~250 μm,250 μm.The environmental factor has large influence on the phosphorus adsorption of sediment.The phosphorus adsorption is endothermic reaction and the increase of temperature is in favor of the phosphorus adsorption of the sediment.The phosphorus adsorption of the sediment has concentration effect.The phosphorus adsorption quantity increases with the increase of the sediment concentration.Under acid condition,the phosphorus adsorption quantity of Wuliangsuhai sediment is less.It increases with the increase of the PH value.


In this paper we describe recent advances in these areas that have enabled us to demonstrate a zinc-germanium-phosphide (ZnGeP/sub 2/) optical parametric oscillator (OPO) driven by a diode pumped holmium laser, capable of multi-watt average power levels in both the near and mid-IR; repetition rates to tens of KHz; and OPO conversion efficiencies approaching 50% (input-to-output) and 70% (slope).<<ETX>>


Unification is the fundamental policy issue for in both North and South Korea. Although American specialists in Korean affairs recognize the importance of this issue, US policy planning for unification and for dealing with a reunified Korea is replete with inadequacies. Planning for US policy could be improved by creating a US Center for Korean Unification Studies to examine the pros and cons of various options and be an instrument for an expanded dialogue between Americans and Koreans from both Koreas. While the United States should develop such a scholarly policy Center on its own, given its track record, it probably will not. Therefore it is the interest of Koreans in both Koreas to back the creation of such a Center and become active participants in the activities of the proposed Center research, conferences, and publications. This is particularly salient for South Korea's many unification-oriented organizations because of the way such a Center would greatly expand US-DPRK interactions in a manner that would benefit the ROK's stake in the inter-Korean negotiations process.


We present the Chandra imaging and spectral analysis of NGC 4968, a nearby (z = 0.00986) Seyfert 2 galaxy. We discover extended (∼1 kpc) X-ray emission in the soft band (0.5–2 keV) that is neither coincident with the narrow line region nor the extended radio emission. Based on spectral modeling, it is linked to on-going star formation (∼2.6–4 M⊙ yr−1). The soft emission at circumnuclear scales (inner ∼400 pc) originates from hot gas, with kT ∼ 0.7 keV, while the most extended thermal emission is cooler (kT ∼ 0.3 keV). We refine previous measurements of the extreme Fe Kα equivalent width in this source ( ), which suggests the central engine is completely embedded within Compton-thick levels of obscuration. Using physically motivated models fit to the Chandra spectrum, we derive a Compton-thick column density (NH > 1.25 × 1024 cm−2) and an intrinsic hard (2–10 keV) X-ray luminosity of ∼3–8 × 1042 erg s−1 (depending on the presumed geometry of the obscurer), which is over two orders of magnitude larger than that observed. The large Fe Kα EW suggests a spherical covering geometry, which could be confirmed with X-ray measurements above 10 keV. NGC 4968 is similar to other active galaxies that exhibit extreme Fe Kα EWs (i.e., >2 keV) in that they also contain on-going star formation. This work supports the idea that gas associated with nuclear star formation may increase the covering factor of the enshrouding gas and play a role in obscuring active galactic nuclei.


The present paper deals with the European works of Rudolf Pannwitz (1881-1969), a German poet and thinker, who suggested to build Europa neither against the nations nor without them, but cooperating with them. The first part of the paper presents Pannwitz's commitment to Europe in the context of similar contemporary European conceptions. Afterwards the second part shows how Pannwitz tries to win some energy from the different nationalisms competing in Europe on behalf of a common European construction ; he relies on the experience of Central Europe in order to demonstrate the possibility of this project.


To protect the safe and economical operation of marine terminal loading and unloading submarine hot oil piplines,the concept of flow assurance is introduced in this paper,and its hydraulic and thermodynamic models are established.When a hydraulic model is being established,the heat capacity varies with the temperature,so the effect of the latent heat of crystallization has to be considered.When a thermodynamic model is established,it uses the sub-calculation method.The latest technologies of flow assurance,including plug prevention technology and flow assurance recovery technology,are presented.Recommendations to improve the domestic flow assurance technology are presented as well.


What are the processes behind efforts for more sustainable mountain destinations in the German Alps and what are the views of different tourism stakeholders on these processes? The research deals both with threats pushing the agenda of sustainable development (such as climate change and depletion of resources), indicators of sustainable tourism (to measure the scope of change), as well as cross-border cooperation and stakeholder engagement in the German Alps. The data was collected through 30 interviews with individuals dealing with tourism development and sustainable tourism development in the German Alps. The findings suggest that a holistic approach and collection and dissemination of data and knowledge on sustainability are the basis for developing sustainable mountain tourism. Implementation and monitoring should focus on specific flagship sustainable tourism products, as well as on a destination in a broader sense and the sustainable tourism market. Three themes emerged as important for implementation of sustainable tourism in the German Alps: indicators of sustainable tourism, cross-border cooperation and stakeholder engagement.


This study aims to investigate the factors associated with the commodity export demand and to explore and quantify the contribution of the commodity export to economic growth. The technique of (VECM) Vector Error Correction is applied to estimate the export and economic growth model. It tests whether there has been a long-run relationship between commodity export volume and exogenous variables such as own price, substitute price, exchange rate, world population and industrial production index. The results indicated that there is a long run relationship among variables. The result suggests that exchange rate have a negative impact to the palm oil, rubber and tin where depreciation may reduce export of these commodities. The findings of the research also show that the commodities export has mixed effect on economic growth in Malaysia. Export of petroleum, palm oil and sawlog has a positive and significant relationship with economic growth in the long run while only petroleum and palm oil contributed to the economic growth in the short run. The evidence of impulse response function shows that exchange rate and FDI shock have a relatively higher significant impact on all exports of major commodities and economic growth respectively. This study implies that export of major commodities in Malaysia should be treated as an engine of growth. The effective management of exchange rate and export promotion policies can play a significant role in increasing commodity exports thus will improve Malaysia economic growth.


Abstract. The accuracy of spatial precipitation estimates with relatively high spatiotemporal resolution is of vital importance in various fields of research and practice. Yet the intricate variability and intermittent nature of precipitation make it very difficult to obtain accurate spatial precipitation estimates. Radars and rain gauges are two complementary sources of precipitation information: the former are inaccurate in general but are valid indicators of the spatial pattern of the rainfall field; the latter are relatively accurate but lack spatial coverage. Several radar–gauge merging techniques that can provide spatial precipitation estimates have been proposed in the scientific literature. Conditional simulation has great potential to be used in spatial precipitation estimation. Unlike commonly used interpolation methods, conditional simulation yields a range of possible estimates due to its Monte Carlo framework. However, one obstacle that hampers the application of conditional simulation in spatial precipitation estimation is the need to obtain the marginal distribution function of the rainfall field with sufficient accuracy. In this work, we propose a method to obtain the marginal distribution function from radar and rain gauge data. A conditional simulation method, random mixing (RM), is used to simulate rainfall fields. The radar and rain gauge data used in the application of the proposed method are derived from a stack of synthetic rainfall fields. Due to the full control over the stochastic process, the accuracy of the estimates is verified comprehensively. The results from the proposed approach are compared with those from three well-known radar–gauge merging techniques: ordinary Kriging, Kriging with external drift, and conditional merging, and the sensitivity of the approach to two factors – the number of rain gauges and the random error in the radar estimates – is analysed in the same experimental context.


Objective To probe the essential aspect and its counter measure in training clinical medical postgraduate students.Methods Based on the review of recently publish papers related and teaching practice for years,the standpoint is put on the need of students in their long-term career after receiving degree.Results Medical ethics and medical information education should be the key point in the teaching plan.Teaching the students in accordance with their apti-tude should be based on their long-term need and the supervisors should be glad for and skilful at education.To put more cost of scientific research to students is in keeping with the China's na-tional policy of invigorating the country through science and technology.Writing clinical case reports ought to be encouraged.Conclusion The noble medical ethics is the motivation force of gaining consummate medical skill.Up-to-date medical information and skill are the necessary capability in getting new knowledge and bringing forth new ideas.Writing case reports is to keep with the reality of students and may deepen the results of clinical observation and accumulate more data on typical case as well as give the bases to further research.


The present invention relates to a control system and method for optimizing the order of certainty based. The control method according to an embodiment includes: performing infeasible search algorithm during a first portion of a predetermined sampling period to search for a plurality of controlled process variables feasible control trajectory, if not infeasible search algorithm to determine a feasible control track, in a predetermined feasible search algorithm performed during a second portion of the sampling period to determine a feasible control trajectory, and controlling the controlled process by applying feasible control trajectory, wherein the search algorithm from viable feasible point in the feasible region starts, and the search algorithm from not infeasible infeasible points in the area start line.


The author details his recognition and confrontation of his stuttering, and how the tools of transactional analysis helped him to shed the negative aspects of his earlier life script.


Morphological characters of Adonis pseudoamurensis W. T. Wang and its related species were examined to illustrate its taxonomic entity, and their new key was made. As a result, it shows that A. ramosa Franch., an endemic species in Japan, was sparsely pubescent on the abaxial surface of the leaf and petiole, and its sepal was as long as its petal. However, A. pseudoamurensis is glabrous on the same surfaces and its sepal was shorter than its petal. In addition, A. multiflora Nishikawa et Ko. Ito was clearly distinguished in that it had acuminate leaf apices, linear shape of the final lobes of leaf and scales on the branched stem. Meanwhile, A. pseudoamurensis featured petiolate at cauline leaves and pubescent on pistils, and these characters were common with their allied groups. But diagnostic key characters suggested by the original description such as sessile at cauline leaves and glabrous on pistils were not observed in this study.


Background : At present, treatment of perforated peptic ulcer has undergone major changes. A vagotomy or resective surgery is no longer the first treatment of choice, since proton-pump inhibitors and Helicobacter pylori eradication can produce the same effect. Recurrence is rare, although when definitive surgery is not performed, symptoms may return and new perforations may occur. Objective : To describe the results of surgical treatment of perforated peptic ulcer. Methods : The research was conducted at the Department of General Surgery of the University Hospital Dr. Gustavo AldereguIa Lima in Cienfuegos, from January 2008 to May 2009. It consists of a case series study including 55 patients diagnosed with perforated peptic ulcer who underwent surgery. Results : 31.2% of the patients with peptic ulcer had previously undergone anti Helicobacter pylori therapy; perforation was the debut of the disease in 45.5% of cases. Despite presenting gastrointestinal illness as medical history, 41.7% of these patients were taking some type of ulcerogenic drugs. The most frequently used surgical techniques were nondefinitive, prevailing suture and non-pedunculated omentoplasty (78.2%). Persistent ulcer was found in 20.0% of patients who could be followed up. Conclusion : After three months of evolution, some of the patients operated on with a nondefinitive surgical technique and anti-Helicobacter pylori therapy did not overcome their health problem.


Vegfb is an endothelial cell-specific mitogen that acts as a potent angiogenic factor. More, it induces blood vessel permeability (Ferrara et al., 1992). Three splice isoforms of mouse VEGF have been described (Houck et al., 1991; Tischer et al., 1991; Breier et al., 1992). Vegfb (–/–) mice (Bellomo et al., 2000) are healthy and fertile but their hearts are reduced in size and display vascular dysfunction after coronary occlusion and impaired recovery from experimentally induced myocardial ischemia. The general features of mouse Vegfb (Olofsson B. et al., 1996) showed two 167and 186-amino acid isoforms arising by alternative splicing of mRNA from a single gene. The use of alternative splice acceptor sites in exon 6 generated two transcripts differing by a 101-bp insertion, corresponding to the VEGF-B167 and VEGF-B186 isoforms. In this report we localize the mouse gene Vegfb to mouse chromosome 19B by coupling in situ PCR and FISH.


Wilber, Gordon O. and Pendered, Norman C. Industrial Arts in General Education. Scranton, Pa.: International Textbook Company, 1967, 3rd ed. 403 pp. Rhodes, James A. Alternative to a Decadent Society. Indianapolis, Indiana: Howard W. Sams & Co., Inc., 1969. 108 pp. Venn, Grant. Man, Education, and Manpower. American Association of School Administrators, 1970. 281 pp. A Guide to Improving Instruction in Industrial Arts. American Vocational Association, Inc., 1510 H Street, N.W., Washington, D. C. 20005, 1968. 67 pp. Towers, Edward R.; Lux, Donald G.; and Ray, Willis E. A Rationale and Structure for Industrial Arts Subject Matter. Industrial Arts Curriculum Project, supported by the United States Office of Education, Bureau of Research, Project No. 5‐0059‐2‐32, Contract No. OE‐5‐85066, 1966. 358 pp. DeVore, Paul W., and Smith, Wil J., eds. Education in a Technological Society. Office of Research and Development, Appalachian Center, West Virginia University, Morgantown, 1970. 89 pp. Rosenberg, Jerry, Editor....


0 any years ago, Helen Keller's mother, Katie Keller, was insistent that the family not abandon the search to find the person who might be able to unlock the mystery of her daughter (Gibson, 1962). Despite the best advice and efforts of professionals and family, Mrs. Keller refused to have her daughter put in an asylum. Would Mrs. Keller be labeled &dquo;in denial&dquo; today? Well-meaning professionals might shake their heads at the IEP meeting and express their genuine concern that this mother is just not able to accept her daughter's pervasive disabilities. After all, it would be obvious to everyone that little t~~~~M Helen could not see or hear. ~~~~~N Wasn't Helen Keller's mother right to be optimistic about her daughter's potential? Mrs. Keller was acutely aware that ~ °9 m


Uncapped InN islands are grown on GaN buffer layers by low pressure metal-organic chemical vapor deposition. The buffer layer threading dislocation density is intentionally altered via the GaN growth pressure, as indicated by both the x-ray diffraction and atomic force microscopy. InN island density and size vary markedly depending on the threading dislocation density in the buffer layers. Islands grown on the buffer layers with reduced threading dislocation densities exhibit narrow x-ray diffraction peaks and strong room temperature photoluminescence.


Following a brief discussion of the relationship between science, technology and the environment, this paper considers the role of science and technology in the formulation and implementation of environmental policy in the UK. It suggests that scientific uncertainty, whether real or perceived, has often been enough to stall the environmental policy process. Consequently, it reviews the attempts that have been made by those government departments and agencies with responsibility for the environment to increase the level of scientific understanding of the environment. It also reviews those research initiatives adopted by government and its agencies to enhance the efficacy and efficiency of environmental policy by ensuring that decision makers at various levels are better informed by advances in science and technology. The paper focuses on the environment-related research activities of the Department of Environment, Transport and the Regions and the Environment Agency for England and Wales. © 1998 John Wiley & Sons, Ltd and ERP Environment.


find a recent period of history in which changes in profit expectations had been, on balance, equal to zero, and then to adjust for inflationary gains. All that the present qualitative argument has shown is that the continued existence of investment programs with positive net present value is a necessary and sufficient condition for a tax on pure goodwill gains to have a positive yield from equity shares. With respect to fixed income securities, the yield of the tax would be negative as long as the expected rate of price change were positive. To recapitulate, I have argued that on grounds of both equity and efficiency a tax system should not include purely inflationary gains in the tax base, and that the tax on asset gains should be levied so as to avoid any disincentive to sell assets with accrued but unrealized gains. I have illustrated the necessary features of the computation procedure, and indicated how the ideas can be simplified so as to reduce the complexity of the calculations. Finally, I have shown that the continued existence of growing investment programs with positive present values is both necessary and sufficient to ensure that a capital gains tax of the sort I am proposing should have a continuing yield from the taxation of equity gains.


Galassetti, Pietro, Yoshiharu Koyama, Robert H. Coker, Drury B. Lacy, Alan D. Cherrington, and David H. Wasserman. Role of a negative arterial-portal venous glucose gradient in the postexercise state. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E1038–E1045, 1999.—Prior exercise stimulates muscle and liver glucose uptake. A negative arterial-portal venous glucose gradient (a-pv grad) stimulates resting net hepatic glucose uptake (NHGU) but reduces muscle glucose uptake. This study investigates the effects of a negative a-pv grad during glucose administration after exercise in dogs. Experimental protocol: exercise (2180 to 230 min), transition (230 to 220 min), basal period (220 to 0 min), and experimental period (0 to 100 min). In the experimental period, 130 mg/dl arterial hyperglycemia was induced via vena cava (Pe, n 5 6) or portal vein (Po, n 5 6) glucose infusions. Insulin and glucagon were replaced at fourfold basal and basal rates. During the experimental period, the a-pv grad (mg/dl) was 3 6 1 in Pe and 210 6 2 in Po. Arterial insulin and glucagon were similar in the two groups. In Pe, net hepatic glucose balance (mg·kg21 ·min21, negative 5 uptake) was 4.2 6 0.3 (basal period) and 21.2 6 0.3 (glucose infusion); in Po it was 4.1 6 0.5 and 23.2 6 0.4, respectively (P , 0.005 vs. Pe). Total glucose infusion (mg·kg21 ·min21) was 11 6 1 in Po and 8 6 1 in Pe (P , 0.05). Net hindlimb and whole body nonhepatic glucose uptakes were similar. Conclusions: the portal signal independently stimulates NHGU after exercise. Conversely, prior exercise eliminates the inhibitory effect of the portal signal on glucose uptake by nonhepatic tissues. The portal signal therefore increases whole body glucose disposal after exercise by an amount equal to the increase in NHGU.


Several factors contributed to the current world demographic configuration: cultural, financial, and socio-economic changes specific to the globalisation process. The improve-ment of alimentation, the recent progresses in the field of medicine, along with mass im-munization, the information and education of the population in the fields of health and care for each stage of life, and practicing mass-sports contributed, as well. From the demo-graphic viewpoint, the main responsible factors are the decreases of the birth rate, increased life expectancy, the migration phenomenon, and population ageing. This latter aspect is the subject of the present paper. The first part reviews the definition of old age from a general and demographic point of view. The second part analyses comprehensively the social vul-nerability of this period of life. The third part is dedicated to the impact population ageing has on the configuration of social policies. From the methodological viewpoint, the paper relies on analysing the specialised literature dedicated to demographic ageing. The paper concludes that demographic ageing is analysed by the Romanian literature predominantly during the past two decades of the post-communist period. The phenomenon has impact on the social insurances system (pensions), medical services and social assistance system (so-cial services dedicated to long-term care).


In this section, we describe the preprocessing including equations in our paper. Assume we are given the embedding support set Sf and embedding query set Qf . We apply centering and l2-normalization to the embedding samples for reconstruction training as described in (A.2). Preprocessed embeddings z ∈ Zpreprocess are used as an input to the reconstruction module gφ. The same preprocessing (centering and l2-normalization) is applied at the output of reconstruction module to compute the reconstruction loss LFR as in (A.5).


Objective By Comparing the early and late coronary angiograms results between cutting balloon angioplasty (CBA) and plain old balloon angioplasty (POBA), to evaluate the efficacy of CBA on coronary in stent restenosis Methods 166 patients with in stent restenosis after PTCA were randomized into two groups: CBA group (98 cases) and POBA group (68 cases) according to the balloon used Its instant and late mimimal lumen diameters (MLD) diameter stenoses (DS) and restenosis rates after PTCA in above two groups were compared Results Although no significant difference in mimimal lumen diameters (MLD) ([2 6±0 6]mm vs [2 7±0 4]mm), diameter stenosis (DS) (% vs %) was observed instantly after the procedure between the two groups, the required balloon inflation pressure was significantly lower with CBA ([8 3±0 9]atm vs [14 7±4 6]atm, P 0 05) At follow up angiography, significant differences were observed in the MLD ([1 7±0 5]mm vs [1 4±0 5]mm, P 0 05), DS (% vs %, P 0 01) and restenosis rates (26 1% vs 40 3%, P 0 05) between CBA and POBA group Conclusion Angioplasty with CB for in stent restenosis, requires low pressure and might effectively decrease the re restenosis rate


This study aims to examine the differences between conventional taxis and online taxis and whether the existing legal regulations are sufficient to regulate the two modes of transportation. The author's curiosity comes from seeing the past when taxis were considered a luxury means of transportation that people rarely use except for emergencies, so city buses and public transportation become the choice of citizens. The choice that was "forced" to be taken considering the low cost and far coverage. Now, when online taxis offer low costs and easy access, the means of transportation that have become "gods" have fallen. The drivers gasped, the transportation entrepreneurs were distracted to finance their business empire and the passengers were no longer greeted by buses and public transportation. This research is a sociological legal research which makes a phenomenon that exists in society and its influence on existing legal rules. The research results show that the difference between conventional taxis and online taxis lies in the amount of tariff, standardization of services, determination of routes and special features and legal protection. The government needs to be firm in regulating the existence of online transportation, given the potential for conflict over disparity in tariff differences and the importance of legal protection for drivers and passengers in driving safety.Keywords:Online Taxi; Conventional Taxi; Legal.


This study was conducted to investigate the effect of supplementing papaya leaf extract (PLES) in drinking water on growth performance, carcass characteristics, meat quality and serum biochemistry parameters of broiler chickens from 0 to 37 days of age in corn-soybean based diet. A total of 520 unsexed one-day-old Cobb-500 broiler chicks were randomly assigned to five treatment groups, with four replicates having twenty-six chicks in each group. Treatment groups were as follows: 0.00, 0.5, 1.00, 1.5 and 2.00 cc of PLES in 1000 ml of drinking water, respectively. The pre-starter, starter and grower diet were fed from 0 to 11, 12 to 26 and 27 to 37 days of age. Body weight, weight gain, feed intake, feed conversion ratio and broiler production efficiency factor (BPEF) were measured for 37 days. Carcass, meat quality and serum biochemical parameters were also measured. The results of the present study showed that non-significantly greater body weight, weight gain and broiler production efficiency factor (BPEF) were observed in PLES groups than control. There was no significant difference in feed intake and feed conversion ratio of broiler chickens in the treatment groups. The relative proportion of dressing characteristics and meat quality in terms of drip loss, cooking loss of breast meat did not alter significantly between the treatments. However, total cholesterol in serum tended (P<0.10) to be reduced in the treated groups than control but other (albumin, total protein, high-density lipoprotein) were not influenced by the treatments. Taken together, our results indicate that papaya leaf extract in drinking water can be supplemented as phytobiotic additive to accelerate growth and improve health status of broiler chickens without any adverse effect.


The Tap StrapTM enables eyes-free mobile typing using a one-hand device worn on the user's fingers. Using the standard MacKenzie-Soukoreff text entry phrase set, 12 participants completed 480 minutes of practice with the keyboard on either their dominant or non-dominant hand. Average final typing rate was 22.11 words per minute (WPM), and letter accuracy increased from 85.11% to 91.02%. Non-dominant hand users typed more accurately than dominant after 420 minutes of practice.


Background
Primary breast cancer (BC) patients with extensive axillary lymph-node involvement have a limited prognosis. The Arbeitsgemeinschaft fuer Gynaekologische Onkologie (AGO) trial compared intense dose-dense (idd) adjuvant chemotherapy with conventionally scheduled chemotherapy in high-risk BC patients. Here we report the final, 10-year follow-up analysis.

Patients and methods
Enrolment took place between December 1998 and April 2003. A total of 1284 patients with 4 or more involved axillary lymph nodes were randomly assigned to receive 3 courses each of idd sequential epirubicin, paclitaxel and cyclophosphamide (iddEPC) q2w or standard epirubicin/cyclophosphamide followed by paclitaxel (EC → P) q3w. Event-free survival (EFS) was the primary end point.

Results
A total of 658 patients were assigned to receive iddEPC and 626 patients were assigned to receive EC → P. The median duration of follow-up was 122 months. EFS was 47% (95% CI 43% to 52%) in the standard group and 56% (95% CI 52% to 60%) in the iddEPC group [hazard ratio (HR) 0.74, 95% CI 0.63-0.87; log-rank P = 0.00014, one-sided]. This benefit was independent of menopausal, hormone receptor or HER2 status. Ten-year overall survival (OS) was 59% (95% CI 55% to 63%) for patients in the standard group and 69% (95% CI 65% to 73%) for patients in the iddEPC group (HR = 0.72, 95% CI 0.60-0.87; log-rank P = 0.0007, two-sided). Nine versus two cases of secondary myeloid leukemia/myelodysplastic syndrome were observed in the iddEPC and the EC → P arm, respectively.

Conclusion
The previously reported OS benefit of iddEPC in comparison to conventionally dosed EC → P has been further increased and achieved an absolute difference of 10% after 10 years of follow-up.


An interesting original edition has been discovered in the Bologna Library, containing the Progymnasmata Thomae Mori et Guilielmi Lilii. These Progymnasmata open with the Epigrammata clarissimi disertissimique viri Thomae Mori Britanni, pleraque e Graecis versa which were integrated in Thomas More's De optimo reipublicae statu deque nova insula Utopia from the Basel editions of 1518 and 1520 (princeps 1516: Libellus vere aureus nec minus salutaris quam festiuus de optimo reip. statu, deque nova insula Utopiae, [Lovanii], Arte Th. Martini, 1516). The pages containing the Progymnasmata also contain a copy of a 1518 edition of Utopia owned by the Bolognese Ulisse Aldrovandi (1522–1605) which was incorporated into the volume of the University of Bologna Library referenced A.V. Tab.I.H.I. 33/1-3. On this excerptum (today referenced A.V. Tab.I.H.I. 33/2) an ancient anonymous hand has written a few very interesting marginalia. Their analysis allows us to propose new hypotheses concerning the Progymnasmata, their...


We assessed whether changeover from open retropubic [RRP] to robotic-assisted laparoscopic prostatectomy [RALP] means a step forward or backward for the initial RALP patients. erefore the �rst 105 RALPs of an experienced open prostatic surgeon and robotic novice—with tutoring in the initial 25 cases—were compared to the most recent 105 RRPs of the same surgeon. e groups were comparable with respect to patient characteristics and postoperative tumor characteristics (all PP P PPPP). e only disadvantage of RALP was a longer operating time; the advantages were lower estimated blood loss, fewer anastomotic leakages, earlier catheter removal, shorter hospital stay (allPP P PPPP), and lessmajor complications within 90 days postoperatively (PP P PPPP). Positive surgical margin rates were comparable both overall and strati�ed for pT stage in both groups (all PP P PPPP). In addition, an equivalent number of lymph nodes were removed (PP P PPPP). Twelvemonths aer surgery, patient reported continence and erectile function were comparably good (all PP P PPPP). Our study indicates that an experienced open prostatic surgeon and robotic novice who switches to RALP can achieve favorable surgical results despite the initial RALP learning curve. At the same time neither oncological nor functional outcomes are compromised.


Screening of 183 wild rose accessions with downy mildew isolates resulted in the identification of 19 resistant accessions. Three of the resistant accessions were tetraploid and belong to the section Cinnamomeae. Crosses were made in spring 2007 between ornamental and the selected tetraploid wild roses to transfer the resistance genes into breeding material. The F1 progenies from the cross 07/57 between resistant R. majalis 93/09-01 and susceptible 'Konig Stanislaus' and from cross 07/44 between resistant R. pendulina D57001 and 'Aprikola' segregate for resistance to single spore isolate 3-16. Histochemical staining revealed the hypersensitive response to be one of the main features of resistance in the population 07/57.


This study aims to determine how big the discussion of the influence of profitability, disclosure of corporate social responsibility and financial performance on firm value with firm size as a moderating variable in manufacturing companies in 2015-2019. The method of data collection is through ICMD and BEI sites and literature studies. The analytical method used is multiple regression analysis. The results obtained based on the partial test (t test) obtained: (a) Profitability partially has a significant effect on firm value (b) CSR partially has a significant effect to firm value (c) partially significant effect on firm value (d) profitability, CSR and firm performance partially significant effect on firm value (e) profitability partially has a significant effect on firm value with firm size as a moderating variable (f ) CSR partially has a significant effect on firm value with firm size as a moderating variable (g) firm performance partially has a significant effect on firm value with firm size as a moderating variable (h) profitability, CSR and performance The company's work partially has a significant effect on firm value with firm size as a moderating variable. Finally, the author suggests that the Manufacturing Company can maximize every existing management division so that the company's performance becomes better and is ogled by investors and potential investors.


TH connection between the army and the general history of Britain has been very little studied. The military historians have limited themselves to specialized studies, while their co-workers in other fields seem often to be oblivious of the fact that Britain has had a standing army at all. The ethos of the British army has been profoundly influenced by the fact that, for the last two centuries, it has filled a double role, both as a continental force and as a body which has spent much of its time in outlying possessions of the Crown, much the most important of which, until the end of the Second World War, was India. So the story of the first royal regiment to serve in India (1754-7), the 39th Foot, has considerable interest. Moreover it is especially rewarding because it can be studied at two levels ; it is well documented in the India Office papers, and the official records are complemented by the papers of Lieutenant-Colonel Samuel Bagshawe, which contain both his own letters and the letters of his brother officers. 1


Second generation OO methods, with a few exceptions, contained no elements addressing process or project management. Third generation methods have been de ̄ned as those collaborative developments which also have a signi ̄cant process element. The two main candidates are Rational Uni ̄ed Process (RUP) and Object-oriented Process, Environment and Notation (OPEN). In this paper, we critique RUP and OPEN from a project management viewpoint and evaluate whether either or both would meet acceptable standards in process support, project management guidelines and full lifecycle description for OO software development. 1. RUP and OPEN: A Comparison While RUP (also UP) and OPEN have many similarities, particularly at the metalevel, there are clear distinctions. The most obvious are that: 2 RUP is a proprietary product and OPEN is in the public domain 2 RUP has limited tailorability and OPEN is fully tailorable (Figure 1) 2 RUP (or at least the Uni ̄ed Process) can only use UML since \UML is an integral part of the Uni ̄ed Process' (Jacobson et al., 1999, p4), whereas OPEN can support any current (and future) notation of appropriate quality 2 RUP must be use-case-driven. Everything relies on the use cases | even the work°ows are derived from use cases (Jacobson et al., 1999, p5) [although how is not stated!] and each iteration deals with a discrete set of use cases (Jacobson et al., 1999, p7). In contrast, OPEN supports use-case-driven, responsibility-driven, data-driven etc. approaches to OO software development 2 While both can be said to be waterfall (or rather serial) at the macro (or business level), RUP uses an embedded waterfall for its iterative structure while OPEN uses an embedded fountain or (objecti ̄ed) contract-driven software engineering process.


In this paper, we build on the mesh improvement methods intended for parallel execution with the paving method [1] and introduce topological changes in an existing quadrilateral-only mesh to improve element shape and nodal valence. This discussion is intended to demonstrate the effectiveness of utilizing mesh cleanup operations as a post-processing step to other mesh generation algorithms. The technique is applied to meshes produced via triangleto-quadrilateral subdivision and octree-based surface generation methods to exemplify dramatric improvement in mesh quality independent of the original mesh structure and generating method.


The accurate prediction of wind power can effectively reduce the wind-free rate of wind power and improve the safety, stability and economy of the power grid. This paper proposes a modified Integrated Ensemble Empirical Mode Decomposition (MEEMD)-Sparse Auto-encoder (SAE)-Elman ultra-short-term wind power combination forecasting method, Which improves the steps of EMD in decomposition process of MEEMD algorithm. using cubic triangular Hermitian interpolation. The MEEMD is used to decompose the wind power raw data into IMF components, the sample entropy value of each IMF components are obtained and the similar of them are combined to reduce the amount of calculate in modeling; Then, a deep learning SAE prediction model is established for high frequency components, while, for low frequency components, an Elman neural network prediction model is introduced; Finally, the predicted value of wind power is obtained by overlaying the former data and analyzing error. Through the comparison of several prediction models in the example, the prediction accuracy of the combined prediction model is improved, which can be applied to the ultra-short-term prediction of wind power.


Malware continuously evolve and become more and more sophisticated. Learning on execution behavior is proven to be effective for malware detection. In this paper, we present MalPro, a DNN based malware detection approach that performs learning on process-aware behaviors for Windows programs. It first employs logistic regression-based weighting method to assess the sensitivity of an API to malicious behavior, and weights the API following run-time arguments with varying degrees of sensitivities. Then, it constructs the process graph of inter-process interactions from which a set of attributes are extracted, for characterizing the relationship of various processes in term of invoke actions. Finally, it feeds the weighted API sequences and the process graph attributes into the DNN for training a binary classifier to detect malware. Moreover, we have implemented and evaluated MalPro on two datasets. The results demonstrate that our method outperforms naive models, verifying the effectiveness of MalPro.


Many professionals, like journalists, writers, or consultants, need to acquire information from various sources, make sense of this unstructured evidence, structure their observations, and finally create and deliver their product, such as a report or a presentation. In formative interviews, we found that tools allowing structuring of observations are often disconnected from the corresponding evidence. Therefore, we designed a sensemaking environment with a flexible observation graph that visually ties together evidence in unstructured documents with the user's structured knowledge. This is achieved through bi-directional deep links between highlighted document portions and nodes in the observation graph. In a controlled study, we compared users' sensemaking strategies using either the observation graph or a simple text editor on a large display. Results show that the observation graph represents a holistic, compact representation of users' observations, which can be linked to unstructured evidence on demand. In contrast, users taking textual notes required much more display space to spatially organize source documents containing unstructured evidence. This implies that spatial organization is a powerful strategy to structure observations even if the available space is limited.


From the perspective of probability, the stability of growing network is studied in the present paper. Using the DMS model as an example, we establish a relation between the growing network and Markov process. Based on the concept and technique of first-passage probability in Markov theory, we provide a rigorous proof for existence of the steady-state degree distribution, mathematically re-deriving the exact formula of the distribution. The approach based on Markov chain theory is universal and performs well in a large class of growing networks.


The plasmasphere is the inner part of the magnetosphere where cold plasma is densely concentrated. The ring current is typically located just outside of the plasmasphere and it consists of high energy ions of tens of keV. Both the plasmasphere and the ring current play important roles in various physical processes in the inner magnetosphere. Although it is normally difficult to observe the global structures of the plasmasphere and the ring current, remote imaging observation from the IMAGE satellite provided the information on the global structures of the plasmasphere and the ring current. We are developing a data assimilation system for estimating temporal evolution of the plasmasphere and the ring current by exploiting the EUV and ENA imaging data from the IMAGE satellite. We have conducted a preliminary experiment using a synthetic data set. The result shows that the spatial distributions of the plasmasphere and the ring current were successfully estimated. The electric potential distribution which controls the distributions of the plasmasphere and the ring current was also well reproduced. This demonstrates that the data assimilation of the EUV and ENA imaging data is a useful tool for reproducing the global temporal evolution of the inner magnetosphere.


The solubility of skins from different fish species: Bolti (Talipia) fish, Wakar (Grouper) and Kishr-Bayad (Nile perch) were investigated using the proteolytic enzymes from their viscera. It was found that by careful control of the pretreatment solution, fish viscera enzymes and skin substrates concentrations, fish skins from different species are readily to become solubilized. Concentration of 5.0% NacL. 3.0% HcL and 3% Acetic acid in addition to the proper concentration of viscera enzymes were found to be efficient in solubilizing skins from all the studied species. Increasing the level of NacL more than 5% had an adverse effect of the conversion rate of the skins; due to its inhibitory effect on fish viscera enzymes. Logestic regression analysis of both the viscera enzymes and skin concentrations were also employed to stimulate the results. From these equations the optimum concentrations of both fish skin substrates and enzyme concentrations to obtain maximum conversions of the fish skins could to predicted.


Artefacts that are present in images taken from a moving rolling shutter camera degrade the accuracy of absolute pose estimation. To alleviate this problem, we introduce an addition linear velocity in the camera projection matrix to approximate the motion of the rolling shutter camera. In particular, we derive a minimal solution using the Gröbner Basis that solves for the absolute pose as well as the motion of a rolling shutter camera. We show that the minimal problem requires 5-point correspondences and gives up to 8 real solutions. We also show that our formulation can be extended to use more than 5-point correspondences. We use RANSAC to robustly get all the inliers. In the final step, we relax the linear velocity assumption and do a non-linear refinement on the fuli motion, i.e. linear and angular velocities, and pose of the rolling shutter camera with all the inliers. We verify the feasibility and accuracy of our algorithm with both simulated and real-world datasets.


Background:
 Very little evidence exists on the prevalence of co-existing cardiomyopathies. We report in this case a highly atypical presentation of concurrent arrhythmogenic right ventricular cardiomyopathy (ARVC) and hypertrophic cardiomyopathy (HCM) likely attributable to simultaneous separate somatic mutations, complicated by stroke.

 Case:
 A 60-year-old male with a history of rheumatoid arthritis, sleep apnoea and obesity with no significant coronary disease referred for review of asymptomatic ECG abnormalities was found to have severe asymmetrical left ventricular (LV) wall thickening with apical segment akinesis and an LV apex mass on echocardiogram. She had a family history of early sudden cardiac death, with an otherwise unremarkable history and physical examination.

 Clinical Course:
 Cardiac MRI (CMR) subsequently demonstrated aneurysmal dilatation of LV apical segments with a 17x13mm thrombus present. Systolic anterior mitral leaflet motion was seen, and a dilated right ventricle (RV) with 240ml end-diastolic volume and 27% ejection fraction. "Accordion" sign was present in the sub-tricuspid RV free wall with dyskinesia, and ECGs confirmed presence of epsilon waves. One week after CMR, she suffered a large left middle cerebral artery (MCA) stroke in the setting of warfarin cessation due to echocardiography-suggestive absence of thrombus.

 Discussion:
 Genetic analysis revealed a mutated Plakophillin 2 (PKP2) gene, and FHOD3 gene associated with HCM of uncertain significance. The diagnosis was concomitant genetic cardiomyopathies of ARVC and HCM complicated by large LV apical aneurysm and thrombus culminating in left MCA stroke. PKP2 mutations to date have not been associated with hypertrophic phenotypes. This case therefore demonstrates the unlikely 1 in 2,500 incidence of coexistence of two separate cardiomyopathies likely attributable to simultaneous separate somatic mutations, while also highlighting the central role of CMR in investigation and diagnosis of RV pathology. In addition to this case, prior studies have also shown echocardiography can only identify 50% of ARVC cases identified by CMR, suggesting that selective use of CMR may double the number of identified cases of this life-threatening disease.


This paper presents a new heuristic approach for multiple traveling salesmen problem (mTSP) and other variants of the TSP. In this approach, the TSP and its variants are seen as constrained resource allocation problems, where an ordered set of resources is associated to the cities, and the allocation is done through an iterative algorithm in such a way that eventually each city gets associated with a resource. The approach allows adding constraints on resources which translate to objectives such as minimum tour length (or multiple tour lengths as in mTSP) and other constraints that define the variants on the TSP problem. The algorithm for the associated resource allocation problem is based on maximum entropy principle (MEP) and the deterministic annealing algorithm. Besides mTSP, this article demonstrates this approach for close enough traveling salesman problem (CETSP), which is known to be computationally challenging since there is a continuum of possible edges between a pair of cities. The examples presented in this paper illustrate the effectiveness of this new framework for use in TSP and many variants thereof. Simulations demonstrate that the proposed MEP algorithm achieves significantly better solutions than the ones provided by the most commonly used simulated annealing algorithm with only marginal increase in run-time.


Non-stoichiometric LiFe1-xPO4/C composites were synthesized by a simple sol–gel method. Different impurities were detected in the X-ray diffraction measurements with the change of Fe content. The effects of Fe-poor on the structure and electrochemical performance of LiFePO4 were investigated. Compared with stoichiometric LiFePO4/C, non-stoichiometric samples show better electrochemical performance because they have smaller impedance and faster lithium ion diffusion. Among these non-stoichiometric samples, LiFe0.94PO4/C cathode delivers the highest capacity of 149 mAh g-1 at 0.2 C and 103 mAh g-1 at 5 C and no capacity loss was found after 100 full cycles.


This document reports on two studies supported under the noted task order. The first part of the report discusses the status of intrusion alarms for work zones. An intrusion alarm detects when a vehicle breaches the work zone and alerts people in the proximate area. The main selling point is to capitalize on being rapidly deployed, while providing advance warning to the workers when a vehicle penetrates the work zone. These devices have an audible alarm (typically 130-120 db) to notify workers and the general public when a work zone breach has occurred. While the concept of an intrusion alarm seems promising, there are many limitations to these systems which make them generally impractical. Additionally, based on the fact that many companies have looked into intrusion alarms and that only one company has an active product line suggests that current systems have significant limitations both from their technical implementation as well as worker acceptance. Additionally, this report covers the finite element crash test simulations on the low-profile barrier to determine the geometry that had the least permanent deflections and best met construction feasibility. The simulations were completed under the guidelines of test level 2 of the National Cooperative Highway Research Program (NCHRP) Report 350. Prior to the crash test simulations, a foundation had to be designed. A 2-dimensional finite element parametric study of various cross-sections for the foundation was studied and one as selected because of its simpler constructability and ability to resist impacts. There were two crash test case studies. The first case tested the maximum permanent deflections (installed in weak soil) whereas the second case tested the barrier structure (installed in rigid soil). The study concluded that both the weak and rigid soil simulations were within acceptable limits.


Whether bullying in childhood has adverse behavioral and emotional effects in adulthood is not well understood. In a prospective, population-based,


An attempt is made here to obtain expressions for the negative limiting gains of Type 0 systems, which are stable for a limited range of negative gains. A simple relation to determine the gain margin of such systems in terms of stability ratio is also obtained.


In 1918 Mellanby identified the "Accessory factor" by curing rachitic puppies with a therapeutic dose of cod-liver oil, that accessory factor is Vitamin D(How et al., 1995). Vitamin D includes, cholecalciferol (Vitamin D3) of animal origin and ergocalciferol (Vitamin D2) of a plant origin. Vitamin D metabolites are of great importance in calcium metabolism, regulating its active intestinal absorption, renal regulation, and its deposition in and mobilization from the skeleton (How et al., International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 9 Number 11 (2020) Journal homepage: http://www.ijcmas.com


approved: Effect of a sudangrass green manure in two soil types on the activity, populations and community structure of soil microorganisms, populations of Verticillium dahliae in soil and on potato roots, and potato early dying, were evaluated in a field microplot experiment in the Columbia Basin. Potato cv. Russet Burbank was grown in identical green manure and fallow soil treatments transported from Idaho and Washington where sudangrass previously suppressed or enhanced early dying of potatoes, respectively. Incorporation of sudnngrass increased total microbial activity (TMA) by 46.2 and 30.1 % in the Idaho soil in 1996 and 1997, and by 43.0 % in the Washington soil in 1996 only. Neither green manure or soil type, however, affected soil populations of Fusarium, total bacteria, or actinomycetes. Across soil type, fluorescent pseudomonad populations were unaffected or increased by 107 % in 1996 and 1997, respectively. Although not repeated across years, Fusarium root populations were 19.7 and 28.3 % higher in sudangrass treated soil from Washington in 1996 and Idaho in 1997, respectively, but the proportion Redacted for Privacy Redacted for Privacy of Fusarium species were similar across soil types. Bacterial rhizosphere communities, based on sole-carbon-source utilization patterns on Biolog GN microplates, did not differ among the soil types or green manure treatments. Across soil type, V. dahliae soil and root populations were unaffected in 1996, but were lower by 20.4 and 41.2 % in Idaho sudangrass soil treatments in 1997. Apical stem populations of V. dahliae and disease severity, however, did not differ among the treatments. Although tuber yield in Washington soil was 31.5 % higher than Idaho soil in 1996, yield was not affected by a sudangrass green manure. Because suppression of early dying of potato observed in Idaho was not replicated in transported soil in the Columbia Basin, the macroenvironment may interact with the sudangrass green manure to regulate the effect, or lack of effect on disease. TMA is not an indicator of disease suppressive ability of a soil following sudangrass as activity increased despite a lack of effect on disease. Based on this study, there is no evidence for differences in microbial populations or communities between the Idaho and Washington soils that could explain the suppression or enhancement of early dying of potato by a sudangrass green manure. Influence of a Sudangrass Green Manure on Microorganisms and Early Dying of Potatoes in Two Soils


This study aims to describe the effect of quantum teaching model-based teaching materials on critical thinking skills of elementary school students. This type of research is development research using a model developed by Borg and Gall. Teaching Material Development starts from the preliminary study phase, planning, product design, product design validation, product trial and final product. The research instruments used consisted of validation sheets, sheets, questionnaires for analyzing student needs, cognitive tests, and tests of critical thinking skills. The research subjects were students in Class V of SDN 1 Cengal, SDN 2 Cengal and SDN 3 Cengal, Japara District, Kuningan Regency. The results showed that there was an increase in students' critical thinking skills using quantum teaching model-based teaching materials compared to students using conventional learning. The difference in this increase can be seen in the results of the gain test of students' critical thinking abilities in the experimental class showing N-gain of 0.59. Then the N-gain in the experimental class is included in the criteria of being. While the results of the test gain students' critical thinking skills in the control class obtained N-gain of 0.20. Then the N-gain in the control class is included in the low criteria


It is a noted fact that the composition of a mixed solid phase grown at non-equilibrium can deviate from the equilibrium composition due to the very low diffusion rate in the solid phase. We present an analytical model for the determination of the kinetic composition of a binary solid phase that is growing from a solution at a given supersaturation, giving rise to kinetic phase diagrams. The model is derived for growth at rough surfaces but is expected to apply also to growth at non-roughened surfaces. Kinetic phase diagrams for different undercooling and excess energy parameters are presented and discussed. If the interaction parameters, describing the excess free energy, are large the model equations can have two stable solutions, which implies the simultaneous growth of two solid phases with different compositions. This kinetic phase separation depends on the undercooling and the composition dependence of the attachment probabilities.


To the Board of Directors: In reviewing recent progress made in the application of electrical power in mines, one is inclined to conclude that it has been effected by the general economic conditions prevailing in the mining industry. Overproduction facilities in men and mines, labor problems, and freight rates are factors which are vitally influencing the prosperity and accomplishments of the business.


The Tales of the Children of War – Ukrainian Independent Modern Theatre The author examines the theme of war in contemporary Ukrainian theatre. Starting with a brief description of the representation of Ukrainian topics in plays directed by Poles, the author puts Polish theatre in contrast with the contemporary Ukrainian drama and stage projects presented by the youngest generation of Ukrainian artists. Focusing on plays by Vorozhbyt, Jurov, and Arie, as well as directorial projects-concepts of Brama, Displaced Theatre or the freak-cabaret Dakh Daughters, the author tries to show the diversity of narratives and perspectives of the textual and formal forms. According to Ukrainians, the war is not a narrative story, but it brings attention to some more complex problems of the Ukrainian society.


A thermodynamic theory for the voltage or free energy generated by a quantum solar energy converter which has recently been proposed, is developed here in a more direct and simpler way. We consider separately the luminescence and conversion of a single photon of the incident radiation. The energy/entropy balance for the conversion process yields an expression for the voltage in a form familiar from the classical thermodynamics of the work carried out by the heat engine. A similar balance for the absorption and emission of light gives an expression for the irreversible entropy generation which reduces the open circuit voltage generated by the solar cell. Detailed expressions for losses due to individual mechanisms, including non‐radiative recombination, are obtained with the use of an approximation where photons in the incident and emitted beams are modelled as an ideal two‐dimensional gas. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


Tracking performance of IMM depends greatly on the selection of model set.A new method was proposed to determine adaptively the model set for IMM based on Input Estimation(IE)method.The acceleration increment could be estimated based on IE.When maneuver was detected,new model set could be determined.Correction procedure would modify the state estimation and its error covariance with new model set.Then IMM estimation could go on with the newly determined model set.The presented IE_VSIMM has simpler algorithm structure and needs fewer rules and parameters. Simulation results show that IE_VSIMM has better tracking performance and can closely keep up with the acceleration change of maneuvering target.


The design of pipelined Fast Fourier transform (PFFT) in modern communication systems provides an efficient way for computation of FFT with better area utilizing hardware architecture. Previously, the radix-22 had been used only for single path delay feedback architectures. Later with many types of research works the radix 22 was extended to multi-path delay commutator (MDC) architectures. This paper presents area optimization of parallel pipelined radix-22 feed forward Fast Fourier transform (PPFFT) architecture. This architecture is provided for parallelism value 4 and 16 sample points and the area of proposed PFFT is compared with other PFFT (feed forward) architectures using the same synthesis tool and FPGA. The comparison shows that the proposed architecture exhibits better area optimization.


With the fast development of the living standard,whole cupboards are more and more popular among the customers.At the stage of the designing,they should be built on the base of science combining the analysis of the ergonomics with the virtual modeling.Through the engineering analysis of CATIA V5,whole cupboards should be designed to meet the request of the ergonomics and produced at a low cost.


Recently, byte-accessible NVRAM (nonvolatile RAM) technologies such as PRAM and FeRAM are advancing rapidly and there are attempts to use these NVRAMs as part of buffer caches. A nonvolatile buffer cache provides improved consistency of file systems by absorbing write I/Os as well as improved performance. In this paper, we discuss the optimality of cache replacement algorithms in nonvolatile buffer caches and present a new algorithm called NBM (NVRAM-aware Buffer cache Management). NBM has three salient features. First, it separately exploits read and write histories of block references, and thus it estimates future references of each operation more precisely. Second, NBM guarantees the complete consistency of write I/Os since all dirty data are cached in NVRAM. Third, metadata lists are maintained separately from cached blocks. This allows more efficient management of volatile and nonvolatile buffer caches based on read and write histories, respectively. Trace-driven simulations show that NBM improves the I/O performance of file systems significantly compared to the NVLRU algorithm that is a modified version of LRU to hold dirty blocks in NVRAM.


The growth of Ge on Ag:Si(111)-√3×√3-R30° has been studied by low-energy electron microscopy (LEEM), low-energy electron diffraction (LEED) and x-ray photoemission electron microscopy (XPEEM). For submonolayer adsorption of Ag at 550°C, the Ag terminated √3×√3-R30° domains decorate the step edges of the substrate. The wetting layer growth and Ge island nucleation on such a step-edge decorated surface is quite similar to Ge growth on bare Si(111)-7×7. During Ge deposition, the √3×√3-R30° domains dissolve and small Ag terminated 3×1 domains are formed that are distributed over the whole surface. Larger 3×1 domains are found only at the circumference of the three-dimensional (3D) Ge islands. From the Ge 3D island morphology, size distribution and density it is concluded that in this submonolayer Ag pre-adsorption scenario there is only little influence of the Ag on the growth kinetics and island geometry. This is completely different for Ge growth on an entirely covered Ag:Si(111)√3×√3-R30° surface. As compared to growth on bare Si(111)-7×7, a strong increase of the diffusion length is observed that leads to a drastic reduction of the island density. Also the island morphology is strongly affected by Ag pre-adsorption in this regime. Instead of triangular islands, we observe huge, irregularly shaped islands that rather resemble a discontinuous Ge film. [DOI: 10.1380/ejssnt.2010.221]


Objective: If there is a natural, inner power or method which can help people transform the feeling of depression, anger, and fear into happiness, harmony and confidence, and maintain the nice feeling, the goal of active aging is approaching. This research explores the effects of emotional perspective transformation and well-being of elders by application of body-mind-spiritual educational program. The main objective is to evaluate the efficiency of a body-mindspiritual program on mood state and well-being of elders. Methods: To achieve the purposes, a 8-week body-mind-spiritual integration program will be designed and well-discussed, and then the experimental pretest-posttest control group design will be implemented. Two questionnaires, POMS and PWB, will be tested before and after. Results: 1.Independent samples T-test and single-factor variance analysis and found that the subjects of sex, age, marital status, occupation and residence in the pre-retirement situation, their personal emotional state at all levels and well-being were not significant differences. 2 Healthy subjects owned higher spiritual vitality than that of ordinary and poor health. 3. By paired-samples t test, only angry-hostility got obvious variance in control group. 4. By paired-samples t test, in experimental group all levels of emotional state, including pressure-anxiety, depression-frustration, anger-hostility, tired-lazy and chaotic-confusion, reached the obvious variance. Moreover, the effects of well-being reached the obvious variance, too. 5. By ANCOVA analysis, those who involved in the body-mind-spiritual program got lower pressure-anxiety (F = 6.835 *), lower depression- frustration (F = 6.235 *), lower tired-lazy(F = 4.958 *), lower confusion (F = 4.464 *), and higher spiritual vitality (F = 8.642 **), than control group.


In this paper, an attempt has been made to summarize the information about the human brain anatomy, information about the brain tumor and cropping the exact location of tumor. X-ray, MRI, Ultrasound etc. are different techniques used to scanning brain tumor images. Radiologist refers these images to get detail information about tumor to analyze the diseases. Digital image processing is one of the useful tools for preprocessing images in medical area for getting more clear and exact details in earlier stages. This is helpful to the physicians and practitioner for diagnoses diseases. Key word: Brain tumor, detection, segmentation, Cropping.


The purpose of the articles is to determine the role of financial stability analysis as an important component of the comprehensive analysis of the entity financial condition. Systematic assessment of financial stability makes it possible to use timely the strategy and tactics of enterprise development, take reasonable management decisions, control liquidity, solvency and financial stability of the enterprise. As a result of the investigation, the following tasks are solved in order to achieve the goal: the type of the financial stability of confectionery enterprise is clarified; qualitative analysis of financial stability is carried out; the dynamics of changes in financial stability is analyzed; financial forecasting by means of integrated indicator based on taxonomic approach is done. General and special methods and techniques of economic problems research for tasks solution such as: synthesis, induction, deduction, generalization, aggregate method, comparative analysis of deviations, coefficient and margin method, standardization of indicators, forecasting, trend analysis method, graphical method are used. The object of the investigation is PJSC «Mondeliz Ukraine». The results of the analysis for the period 2017–2020 indicate the unstable financial condition, violation of the enterprise financial stability; but due to the trend line we forecast the increase in the integrated taxonomic indicator of financial stability in future. The generalized indicator of the change of enterprise financial stability confirms conclusion about the increase of enterprise financial stability in dynamics. The solution of the problem of increasing the financial stability and balance of PJSC «Mondeliz Ukraine» and increasing the availability of own funds is possible primarily by increasing sales, profits and, accordingly, increase profitability. However, measures to strengthen financial stability can give positive results only if they are comprehensive, systematic, mandatory. The prospects for further investigation are to identify the relationship between the level of financial stability and the synchronicity of the enterprise time-balanced cash flows formation.


Objective
To investigate the prenatal ultrasonographic features and prognosis of vasa previa, to explore the application value of sector scanning in the intracervical mouth by antenatal ultrasound, then to increase vasa previa detection rate.

Methods
Prenatal ultrasound images, clinical characteristics and pregnancy outcome of 35 pregnant women with vasa previa confirmed by surgery and pathology were analyzed retrospectively, the diagnostic effectiveness of sector scanning in the intracervical mouth was evaluated.

Results
Thirty-three of the 35 vasa previa cases were detected by sector scanning in the intracervical mouth, with a detection rate of 94.3% (33/35). Of the 35 cases, 20 cases (60.6%) were first contacted in second trimester and 13 cases (39.4%) were first contacted in third trimester. Two cases were missed or misdiagnosed, which were all first contact in third trimester. Among the 35 cases, 25 were velamentous placenta and 4 were battledore placenta. Twenty cases were low-lying placenta or marginal placenta previa. All 35 women underwent cesarean section. No neonatal mortality, 11 term infants, 20 premature infants of more than 34 weeks and 4 premature infants of less than 34 weeks. All placentas underwent pathological examination after delivery, 4 cases placentas underwent vascular casting, and it was found that 2 cases were vasa previa of umbilical artery branch and 2 cases were vasa previa of allantoic veins branch.

Conclusions
Vasa previa can be effectively detected by prenatal ultrasonography through sector scanning in the intracervical mouth. Second trimester is the best period to detect vasa previa. Pathomorphological examination on placenta after delivery and vascular casting are helpful to the understanding of vasa previa.

Key words:
Ultrasonography, prenatal; Vasa previa; Vascular casting


Abstract: The Washington Consensus as conceived in 1989 by John Williamson, the initiator of the term, was the foundation of the mainstream perspective on international development. The Washington Consensus consisted of a set of ten policies to be imposed through conditionality by international financial institutions on distressed developing countries. The vast criticism that ensued brought a set of policies in the form of the After the Washington Consensus (hereafter the AWC) in 2003, which designated a "new" set of policy reforms and conditionalities for developing countries. The aim of this article is to contrast the two sets of controversial policies, the original Washington Consensus and AWC, to an alternative perspective of international development based on an institutionalist approach.


Some photosynthetic characteristics of two pear varieties(Pyrus bretschneideri Rehd and Xinli No.7) were studied,Analysis their photosynthesis general character and the characteristic,The results showed: Diurnal change of sunny day in net photosynthetic rate(Pn) in Pyrus bretschneideri Rehd and Xinli No.7 were typical ″none-drop″ bimodal curve,and the phenomenon of″the midday rest″ were obvious.Pn daily variation of cloudless day were the split-blip curve.″The midday rest″ phenomenon in Xinli No.7 was more obvious than Pyrus bretschneideri Rehd,also the photosynthesizes ability under the cloudy day weak light condition was stronger than Pyrus bretschneideri Rehd.The light compensation points and light saturation points approximately was 1 392 and 42 μmol/(m2·s),the apparent quantum yield was 0.048 2 mol/mol.When photoinhibition occurred in Xinli No.7,AQY and Pn decreased obviously.


B. Tsondek (1930), analyzing the hormonal changes in the female body in menopause and menopause, distinguished the following three phases of menopause: 1) hyperfollicular, when a woman's body has a large amount of estrogenic hormone (hyperestrogenism), 2) hypoghormonal, or agormonal, when there is an extremely a small amount of both estrogenic and gonadotropic hormone of the pituitary gland, and 3) hypergonadotropic, when there is no estrogen hormone in the body at all, but there is a significant amount of gonadotropic hormone.