Data collected as part of two cross-sectional surveys to investigate metabolic outcomes and markers of inflammation in urban and rural locations in Uganda. It contains information obtained from 313 participants (one row represents one participant). 48 variables are recorded, including data on inflammatory markers (cytokines and chemokines), location of residence (urban versus rural), metabolic parameters (including HOMA-IR, blood pressure, blood glucose) and socio-demographic characteristics.


This report describes an infant with trisomy 13 associated with imperforate anus. Clinical features of patau syndrome described in standard texts do not include imperforate anus or anorectal malformations (ARM). In our search of the English literature only four cases of trisomy13 have being associated with imperforate anus: a de novo mosaicism 46, XX, t(13q13q)/46, XX,-13,+r(13), a partial trisomy of chromosome 13q and 20p and trisomy 13 with Robertsonian translocation of extra chromosome 13 to chromosome 14. The fourth case of trisomy 13 has been mentioned by Cho et al in 2001 in which the form of trisomy has not been described. This baby girl was born at term by emergency caesarian section for fetal tachycardia to non consanguineous parents. On initial examination the she was noted to have overlapping fingers, widely spacednipples, ulnar deviation of hands, microphthalmia with ectropion of the right eye. Systemic examination revealed imperforate anus and a systolic murmur. The baby was transferred to a surgical unit and had a colostomy on day one of life under general anaesthesia. She was discharged home on day 21 of life. Out of the four cases of trisomy 13 described so far with imperforate anus all have been either mosaics or translocations. Our baby is unique as she is possibly the only reported child with Patau syndrome 47 XX + 13 (pure non disjunction and not mosaic/ translocation) to have anorectal malformation. It is still questionable whether imperforate anus is a true association of trisomy 13 or just a co-incidental occurence.


Temperature distribution, and efficiency of a rectangular profiled longitudinal fin are examined in this investigation with the impact of the magnetic field. By exploiting appropriate non‐dimensional terms, the heat transfer equation incorporating temperature‐dependent thermal conductivity, heat transfer coefficient, and Maxwell expression for the effect of the magnetic field yield a dimensionless nonlinear ordinary differential equation (ODE) with corresponding boundary conditions (BCs). Sumudu transform method with Pade approximant (STM‐PA) has been employed to obtain an analytical solution for the temperature profile of a longitudinal rectangular fin subjected to a uniform magnetic field under multi‐boiling heat transfer. The STM‐PA results are compared to the Runge‐Kutta Fehlberg's fourth‐fifth (RKF‐45) order technique for computational verification and are observed to be in good accordance. The behavior of dimensionless temperature profile has been explicated graphically for diverse values of non‐dimensional parameters such as thermal conductivity parameter, Hartmann number, and thermogeometric parameter. The results of this study show that as the thermal conductivity parameter enriches, the temperature profile of the longitudinal fin improves, whereas it declines for the Hartmann number and thermogeometric parameter. Under multi‐boiling heat transference, fin efficiency varies significantly depending on the impact of pertinent variables.


The work focuses on the question of destination marketing in relation to the social network. Marketing on social network, marketing on Facebook and analysis of Facebook page options are defined here. In the analytic part, the analysis of official Facebook page of destination Eastern Bohemia is made. The analysis has two points of view. In the practical part is the system improvement.


Temperature warping stress of plain concrete plate calculated by Westergaard formula and finite element method(FEM) was comparatively analyzed.It demonstrates the applicability of plain concrete plate model,and an important conclusion is drawn that body weight produces no effect on warping stress.Based on three-direction spring simulating the bond-slip relation between steel and concrete,warping stress alteration of feature points before and after reinforcement was calculated.Influence of the following parameters on the change of warping stress before and after reinforcement could be neglected,such as reinforced layer location,bond-slip stiffness coefficient,temperature gradient,plate length,plate thickness and reinforcement ratio.The results show that temperature warping stress calculation method of separate plate of continuously reinforce concrete parement(CRCP) under Winkler foundation is the same as its size of ordinary Portland cement concrete slab.


Improving executive capacity of government is the essential requirement of government's work,it is the request of building a service-oriented government and the key to improve the rationality and effectiveness of government works.After analyzing the factors which hinder the improvement of government executive capacity in our country,this article introduces the path selection plan to improve the present government executive capacity,in order to help the construction of such capacity.


Background: After the addition of differentiating agents such as all- trans retinoic acid (ATRA) to conventional chemotherapy, treatment outcomes of acute promyelocytic leukemia (APL) had been markedly improved. However, about 10% of patients with APL still have experienced relapse and have to receive salvage chemotherapy. Although arsenic trioxide (ATO) plays an important role in salvage chemotherapy as well as induction chemotherapy, the optimal treatment strategy remains unclear, especially for patients in whom autologous peripheral stem cell transplantation (AutoHCT) is planned. We tried to find the role of salvage chemotherapy including ATO-based regimen in relapsed APL patients, and want to share our experience in these patients. Patients and Methods: Among 77 patients diagnosed with APL from 2005 to 2014 at Yonsei University Severance Hospital, 11 (14.3 %) relapsed patients were enrolled. Clinical data of these patients was retrospectively reviewed. Except one patient refused further treatment at the time of relapse, 10 patients were included in the final analysis for treatment outcome. Results: All patients received remission induction chemotherapy with modified PETHEMA regimen, and achieved complete remission (CR) confirmed at the molecular level. The median duration of the first CR was 38.8 months (range 28.0–88.0 months). As pre-transplant salvage chemotherapy, earlier 3 patients received conventional chemotherapy regimen without ATO, but later 7 patients received ATO-based regimen after ATO was available in our country. There was no statistical difference in median duration to the second CR from salvage chemotherapy according to the regimen (68 days in conventional chemotherapy patients vs. 60 days in ATO-based chemotherapy, P>0.05). However, 3 patients receiving conventional regimen without ATO did not received AutoHCT because they died due to treatment-related complications during additional salvage chemotherapies. In contrast, 7 patients receiving ATO-based regimen received AutoHCT successfully, and all patients remains alive without further relapse. The median duration from the time of second CR to AutoHCT was 3.8 months (range 1.3–7.6 months), and median follow up duration after AutoHCT was 8.3 months (range 0.6–45.9 months). In these 7 patients receiving ATO-based regimens, duration of ATO treatment was variable (median 72 days, range 42-113 days), and a range of total dose of ATO given before AutoHCT was also variable (median 701.23 mg, range 420-1242.8 mg). Total dose and treatment duration of ATO was mainly determined by the time of molecular CR achieved again. The peripheral hematopoietic stem cells were harvested when molecular complete remission was confirmed, and median number of stem cells harvested was 5.14 x 10^6 cells/kg of recipient (range 2.90–7.76 x 10^6 cells/kg). The yield of harvest peripheral stem cells and the outcomes of followed AutoHCT were not significantly related to the total dose or treatment duration of pre-transplant ATO-based salvage therapy. Conclusion: In this study, ATO-based chemotherapy followed by AutoHCT was safe and excellent salvage treatment strategy for relapsed APL patients. The achievement of second molecular CR might be more important in this treatment strategy than total dose or treatment duration of ATO-based salvage therapy before AutoHCT. Disclosures No relevant conflicts of interest to declare.


Electronic health records (EHRs) are becoming an important aspect of how members of a healthcare organization organize and share patient information effectively and efficiently in patient care. EHRs can provide substantial potential benefits to healthcare providers, if roles and tasks are well coordinated between providers and patients. Poor or incompatible implementation of the EHR and information flow between patients and providers represents barriers to accurate and valid information dissemination. The authors' research expands on previous studies, and examines privacy and security issues and the perspective of distributed expertise incorporating both providers and patients. The case study to be highlighted examines patient and provider perspectives of expertise, communication effectiveness, and the sharing of information (with and without the EHR) in outpatient OB/GYN clinical care.


Vocational practice teaching in a planned way,mainly through students,through observation,experimentation,operation,training,etc.to consolidate and deepen teaching and professional training relevant to the objectives of theoretical knowledge and expertise,have engaged in practical work the fields of basic capabilities,basic skills.Practice the role and status of teaching can not be ignored,but in practice not be optimistic about the status of teaching,this article analyzes the practice of teaching in teacher education and facilities under the premise of the status quo,given the development of practical teaching model and development strategy.


Abstract. Plummers Island is a small island located in the Potomac River in Montgomery Co., MD. Bees have been collected and cataloged from Plummers Island since 1909, but their floral associations have not been thoroughly described. As bees are important pollinators of natural and managed terrestrial ecosystems, monitoring their floral host choices is an important step towards proper land management and conservation practices. We collected bees from flowering plants on and adjacent to Plummers Island over two seasons and characterized their interactions using a bipartite plant-bee visitation network. Seven hundred and forty individual bees visited 30 species of flowering plants currently classified in 17 different genera. The resulting network was characterized by nested, asymmetrical interactions, but did not show strong evidence of either extreme generalization or specialization. The plant with highest interaction frequency score (species strength) was the invasive poison hemlock, Conium maculatum (Apiaceae), while the common sweat bee, Augochlora pura (Halictidae) had the highest interaction strength for the bees. We discuss these results considering species phenology and potential sampling biases and compare them to previous records for the island.


The cause of acute urethritis was studied prospectively in an unselected group of 62 male university students. Urethral exudate and urine samples were cultured forNeisseria gonorrheaeand T-mycoplasmas, and the results were compared with findings in a similar group of 70 healthy controls. Only 8% of the patients were found to have gonorrhea by culture. Of the remaining 57 patients with nongonococcal urethritis, 76% were positive for T-mycoplasmas while 27% of 70 controls were carrying the organism. Symptoms in patients with nongonococcal urethritis cleared during therapy with tetracyclines or erythromycin, and posttherapy cultures for T-mycoplasmas showed only a 28% carriage rate. Nongonococcal urethritis was much more common than gonorrhea in this student population, in spite of the epidemic of gonorrhea occurring in the United States. In addition, the view that T-mycoplasmas may be a cause of nongonococcal urethritis was supported by this study.


The 5G Internet Radio-Light (IoRL) project aims to provide reliable intra-building wireless networks by using visible light and millimeter wave parts of the electromagnetic spectrum in addition with existing WLAN networks. One key aspect of the project is to provide reliable high-quality video streaming, which is difficult to do using state-of-the-art single-path video streaming systems in case of wireless network failure. By taking advantage of the plural network paths available by design in the IoRL architecture, we propose Multiple-Source Streaming over Remote Radio Light Head (MSS/RRLH), a DASH-compliant end-to-end multiple-path streaming system increasing both the reliability and the Quality of Experience (QoE) of the streaming sessions. The solution has been experimented and evaluated in the IoRL context and shows a significant decrease of stalling events while maintaining a low end-to-end delay for live streaming sessions.


The feeding mucus in larval lamprey is produced by the lateral walls of the pharynx and by glandular goblet cells on gill filaments. The mucous complex has 14 lateral branches which move inward to the middle of the pharynx, where they are collected and directed back to the esophagus. Mucus, which is carried by intrapharyngeal ciliary tracts and water currents, fills virtually every space in the pharynx, resulting in high (75%) entrapment efficiency. Based on indirect calculations, algae accounted for only 0.14–1.5% of the gut contents in larvae of European brook lamprey (Lampetra planeri). Although the bacterial film associated with algae, detritus, and sand grains may be an energy source for ammocoetes, suspended bacteria cannot support growth in laboratory experiments. Selective feeding on different species of algae is common among lampreys and is based on three factors: (1) susceptibility to capture in the feeding–respiratory flow differs among particles, (2) filtration of long filaments by the oral ci...


By providing different forms of performance feedback before choosing between a piece-rate and a tournament compensation scheme, I test whether the gender tournament gap diminishes in size since individuals' entry decision might be driven by incorrect self-assessments. Only the provision of information on average performance by gender indeed shrinks the gender tournament gap, which is especially due to men with below average ability opting for the piece-rate more often. These results highlight that beliefs on one's own and others' abilities are still biased by gender stereotypes.


Stearic acid monolayers with various areas per molecule ( a ) were deposited on SiO2 (or Al200 surfaces by the Langmuir-Blodgett method under various surface pressures. The phase transitions from the two-dimensional gas state to liquid state (a =O. 24 nm2) and the liquid state to the solid state (a =O. 20 nm2) were clearly observed in the n--A isotherm of the monolayer spread on the subphase. From ellipsometric and reflectionabsorption FT-IR measurements, the thickness and the molecular tilt angle were determined to be 2. 28 nm and 27. 6 from the surface normal for the sample with a a value of 0. 20 nm2, respectively. Wetting properties for water were evaluated as a function of molecular coverage. The static contact angle increased and the critical tilting angle (CTA) decreased as the coverage increased. Two discontinuous changes of the contact angle were found near the coverages where the phase transitions on the subphase occur. These findings were discussed in terms of the interaction between water and the surface of the sample quantitatively evaluated from the plots of tan CTA vs. {m"3 cos CTA}-' (m is the mass of water droplets). Key-words : Langmuir-Blogett film, Reflection-Absorption FT-IR, Wetting, Water Repellent Glass


Electrical insulators of the Provincial Electricity Authority (PEA) of medium system are mostly porcelain insulator types that consist of pin type, line post, and pin post insulators. The distribution lines will be polluted by industrial contaminants, salt fog or natural dust. Experience shows that pollution flashover is one of the main natural calamities harming and affecting the voltage stability and reliability of distribution system. This paper compares the test results obtained from the artificial pollution tests according to IEC 60507 in the chamber for tests with standard porcelain insulators consist, pin post, line post and pin type insulators of medium system under same test conditions. The salt fog test results indicate that the pollution flashover performance of pin type insulator is less than to 50 percent of wet power frequency withstand voltage at equivalent salt deposit density (ESDD) = 0.5 mg/cm2 and the leakage current (LC) of pin type insulator increased to 11.4 mA at ESDD = 0.5 mg/cm2 at nominal voltage. In the experiment indicate that AC pollution flashover performance of pin post insulator has better than line post and pin type insulators in the serious pollution area. This data will be useful to be guideline for solving problems and reducing power loss from leakage current on the surface of the insulators as a result of surface dirt and pollution. Moreover, it will be useful to select or design suitable insulators for using in places with salt conditions, high rainfall, high wind speeds and high humidity.


In this article the concept "acquirer" lifestyle is defined and in this context the essence, nature and mechanisms of functioning of mass fashion are revealed, analyzed in detail valuable orientations and sights of youth at a fashion, conditions and the reasons for access to material benefits.


Low Temperature Cofired Ceramic (LTCC) is used as a substrate material for microelectronic devices in satellite communication. Its dielectric properties and excellent variability allows a good compactness and a high level of integration. An LTCC antenna array for microwave signals operating at 30 GHz is presented. All components such as radio frequency distribution network, four waveguide phase shifters and horn antennas are integrated in one ceramic module. The phase shifters are implemented as high volume cavities in the LTCC. A tailored mixture of liquid crystal can be stored inside the cavities. By applying an electric field, the anisotropic LC-molecules are aligned. The field is provided through a biasing network with four electrodes and screen printed resistive layers with resistance values in the MΩ/□ range. The alignment and with it the phase shifting is nearly seamless. The antenna module is manufactured in multilayer technology and consists of more than 40 layers. Lamination is carried out by th...


In order to sensitize the luminescence of Eu3+ ions in heavy metal glass,zinc lead borate glass samples containing various concentrations of Eu3+ and Tb3+ ions were prepared to study the Tb3+ to Eu3+ non-radiative energy transfer phenomena.Energy level structures of Tb3+ and Eu3+ ions were plotted to show the excitation and energy transfer routes.Efficient energy transfer from Tb3+ to Eu3+ was observed and studied qualitatively in terms of doping concentrations.The sensitization turned out to be less effective than expected.Further studies to characterize the oxidation of Tb3+ into tetravalent state and to examine the mechanism of energy transfer are proposed.


Procedure for a user equipment, UE, for transmitting two types of pilot signals to a base station enun mobile communication system, the method comprising: transmitting, from the UE, pilot first type signal associated with data transmission to the estacionbase in a subframe where the UE is scheduled for data transmission, wherein the subtramacomprende a first unit time domain for transmitting a first pilot senalpiloto the first type signal and a second unit time domain for transmitting a second signal pilotode the pilot of the first type signal, and characterized by transmitting, from the UE, pilot of the second type signal not associated with data transmission laestacion based on a subframe specified based on a value of period and dedesplazamiento value, in which the value of time and the offset value are received from the estacionbase through signage, in which e l UE transmits the first pilot signal in the first unit time domain and transmits lasegunda pilot pilot of the first type with the pilot of the second type signal in segundaunidad time domain in a specific subframe signals signal, where the UE is transmitirdatos and programmed to the specific subframe is specified based on the period value and the offset value.


This article discussed that it is essential to educate creative talent in the computer experiment teaching,there are many shortcomings on creative talent education,and bring forward corresponding approaches to solve these problems. There are some significance to educate creative talent in the computer experiment teaching.


Research question. The European shift towards constitutional justice. The Dutch peculiar approach to constitutional adjudication. Different approaches towards constitutional review of legislation: a comparative framework. The atypical relationship between the Dutch constitutional system and the ECHR: does the conventionality review supplement the lack of constitutional review? Is the Dutch system a model on its own?


We study an integrable system related to the relativistic Toda lattice. The bilinear representation of this lattice is given and the Bäckulund transformation obtained. A fully discrete version is also introduced with its bilinear Bäcklund transformation (BT) and Lax pair. One-soliton solution of the discrete system is presented by use of BT.


Dengue Virus Infection (DVI) causes several clinical manifestations and requires varied diagnostic instruments. IgA anti-dengue as one of the diagnostic markers of DVI is suspected to have a shorter lifespan and greater sensitivity in detecting secondary infections compared to IgM anti-dengue. This study was conducted using 34 sera with positive RT-PCR or NS1 dengue virus. Samples were examined by a reverse flowimmunochromatographic method using AIM Dengue IgA Assure Rapid Test and will be analyzed its profile toward the day of fever, serotype, severity, platelet count, and type of infection. The overall sensitivity of IgA anti-dengue was 61.76% (n=34); in which IgA anti-dengue detected 14.29% primary and 66.67% secondary cases. IgA anti-dengue detected DEN1, DEN2, DEN3, and Mixed DEN1 – DEN3 virus serotype respectively 55.56%, 22.22%, 16.67%, and 5.56% (n=20). The day of fever was dominated by day-4 and day-5 respectively 28.57% (n=21). IgA anti-dengue was detected in DD, DHF grade I, II, and III 42,86%, 28.57%, 19.05%, and 9.52% (n=21) respectively. IgA anti-dengue detected in all levels of platelet count, it detected 60% in < 50,000 cell/mm3, 30% in 50,000 - 100.000 cell/mm3 and 10% in > 100,000 cell/mm3 platelet count sample (n=20). In conclusion, IgA anti-dengue showed a good performance, applicable as a diagnostic marker of DVI.


9573 Background: The risk of second malignancies is 3-6 times more in childhood cancer survivors. The 20 year cumulative risk of secondary malignancies in 14,193 chilhood cancer survivors followed for >5 years was 3.2% (Cancer 2005).

METHODS
1,500 childhood cancer survivors treated between 1990-2010 in the Istanbul University, Oncology Institute were evaluated for second malignancies.

RESULTS
16 second malignancies were identified in 15 childhood cancer survivors in a median time of 6 years. The 16 second malignancies were: 4 acute myeloblastic leukemias (AML), 2 malignant nerve sheath tumors (MNST), 8 sarcomas, 2 breast cancers. AML was diagnosed in 4 children in a median of 31 months (13-60 mo): The primary diagnosis were Ewing's sarcoma, osteosarcoma, non-Hodgkin's lymphoma and neuroblastoma. Two of these children had recieved multiple therapies for recurrences. Two children with a primary diagnosis of medulloblastoma and neuroblastoma developed MNST in the radiation field after 9 years. A Ewing sarcoma patient developed sarcoma after 6 years, an osteosarcoma patient developed breast cancer after 8 years, an ALL patient developed Ewing sarcoma after 3 years, a mesenchymal chondrosarcoma patient developed breast cancer after 11 and osteosarcoma after 16 years. These were not in the radiation field. A soft tissue sarcoma, and an osteosarcoma developed in two bilateral retinoblastoma patients both after 14 years, a sarcoma developed in a rabdomyosarcoma patient after 6 years and in a patient treated for nasopharyngeal carcinoma after 3.5 years all in the radiation field. An extremity osteosarcoma developed in another bilateral retinoblastoma patient after 4 years. The two patients that developed breast cancer and the six patients that developed sarcoma are alive. All others are dead of disease.

CONCLUSIONS
The risk of secondary malignancies in our series is 1% and low in comparison to the literature. However, it has increased within years and may still increase as the follow-up time increases. Since, the risk of second malignancies is associated with the cumulative dose of some chemotherapeutics, the radiation dose/field, the use of minimal therapy that has the maximum efficacy according to the diagnosis, age, stage and risk of the patient is important.


206 Professional Case Management Vol. 20/No. 4 A hallmark of professional case management practice is assessment. This primary element of the case management process ( Powell & Tahan, 2008 ) serves to set the tone for all subsequent interventions that are required on behalf of patients, clients, members, and/or consumers. A case manager's efforts can all be for nothing without a solid comprehensive effort to view all the unique moving parts that accompany any patient situation. No greater place does this apply than in the context of situations where a case manager must go through the mental calisthenics required when a patient is in immediate risk of harming him/ herself or others. Past articles in this and other journals have addressed the topic of clarifying how and why a case manager must invoke their mandatory duty to warn ( Corbin, 2007 ; Granich, 2012 ; Fink-Samnick, 2013 ; Muller, 2013 ). The prior column spoke to the laws and distinctions that exist between a case manager's responsibility to report child and adult abuse, neglect and exploitation, and duty-to-warn and/or report situations. The increasing frequency and severity of mass violence episodes have heightened societal awareness of the acute need to do "in the moment assessment" of these situations. "Societal dialogues following mass shootings follow a similar unfortunate cycle: initial horror and tragedy transition to personal/professional outrage, mourning, and ultimately blame" ( FinkSamnick, 2013 , p. 151); blame is usually directed at any involved professionals who have interfaced and/ or treated the accused. The stakes present as even higher these days where increased assessments are being conducted by licensed professionals remotely, in cyberspace, or both ( Fink-Samnick, 2013 ).


The concepts of agile manufacturing and/or the virtual corporation have been under discussion for some time and various authors have cited examples in the shipping, needle trades, and entertainment industries. The aerospace industries have begun to show the benefits of concurrent engineering and strategic planning for manufacturing. The authors have created a laboratory scale manufacturing environment to explore the benefits utilizing an advanced set of interactive multimedia tools in conjunction with video conferencing to discover the issues and benefits of applying these tools to the general manufacturing company. Preliminary results are encouraging but indicate that new tools and changes in management will be needed before agile manufacturing becomes common place. This presentation covers a variety of case studies and prototypical environments for recording and managing multi-point video conferences. Ubiquitous tasks such as: engineering change orders involving multiple vendors or staffs, creating and recording of the minutes of a multi-site meeting, and ordering a late night pizza are undertaken with these new tools and captured on video to illustrate the talk.<<ETX>>


The critical period of competition defines how long weeds can compete with crops before affecting yields. Two critical periods are defined. The first involves weeds that emerge at the same time as the crop and compete until a postemergence strategy is applied. These weeds have the greatest potential to affect crop yields and are the focus of this article. The second critical period involves weeds that emerge after crop emergence. As the interval between crop and weed emergence increases there is less likelihood that the weeds will impact yields.


How are they related to each other? This chapter seeks to answer these questions. Answering the first is simple. Obviously, the current world order cannot be fully understood without taking 'globalization' into consideration. The effects of Globalization reach every corner of the world in different scope and degree. Why is 'civilization' important? It is important because civilization incorporate the essence of world order. Civilization as we will see later on, contains and reflects both economic, social, cultural and political aspects and dimensions of the world order. We define a great civilization as a junction between a world vision and a historical formation. The answer to the second question constitutes the main subject of this chapter. We will (1) analyze the relations between civilization and world identity; (2) explain how globalization is related to world economy; and finally (3) we will bind the three concepts (globalization, civilization and world order) together by proposing three models on world order.


The real-time holography system with a liquid-crystal television spatial light modular (LCTV- SLM) is presented. In the system, the LCTV-SLM is used as a phase hologram device. On the recording, the in-line holography method is used to reduce the spatial frequency of the fringe pattern of the hologram. The CCD camera detects the fringe pattern, and the fringe-pattern signal is transferred to the LCTV-SLM through the video-signal line. On the reconstruction process, the LCTV-SLM is illuminated by an He-Ne laser (633nm) and the spatial filtering technique is used to remove the zero and the higher-order diffracted light. Thus the holographic image of the real object can be observed continuously in real-time.


Hamartoma is complicated in its components,manifesting as tumor-like malformation from abnormal development but occasionally as mesenchymal tumor.Adipose and calcification are characteristics of most hamartomas.Pulmonary hamartoma exhibits popcorn-like calcification.Renal hamartoma is complicated with nodular sclerosis in 20% of cases.Liver hamartoma presents as cystic solid masses,whereas intrahepatic biliary hamartoma manifests as multiple irregular cysts.Chest wall hamartoma contains bone-like density and mixed calcification lesions.Hypothalamic hamartoma results in elastic epilepsy and sexual precocity.


The most significant long-term threat to agrobiodiversity, considered, is climate change. Driven by different transformation in climate and socio-cultural structure and also related the lack of collective knowledge of diversity about the Peruvian Andes. The identification and documentation of local ecological knowledge has recently become important in research, also acknowledging the importance of the farmer's experience. Three communities in the district of Haquira (Pauchi, Queunapampa and Huancacalla Chico) in Apurimac, Peru have been surveyed to identify and document the native potatoes name's and to determine the actual state of potato landrace for long term monitoring. The objectives focused on identifying local experts and their knowledge using Five Cells Analysis (FCA) method and GIS Participatory for Red List, the factors taken into account for survey were biological, ecological, economic, social and cultural suggested by Community Biodiversity Registers (CBR). It was registered by focus groups household (n=61) and the methods employed quantitative sampling (GIS) and qualitative sampling (FCA), which complement allowing recognition 174 names of local varieties, 45 varieties have different taxonomic names and 42 varieties have 71 same taxonomic names in the three communities. The results provide us information systematization of native potatoes to prepare a master list that can be evaluated against genetic information.


According to the characteristics of construction of precast elements in Tianjin Port and the experience in precasting concrete elements during the winter from 2011 to 2012,this paper presents some heat preservation measures in precasting hydraulic concrete elements,providing reference for similar construction.


Determining the etiology of epilepsy is a very complicated problem. Epilepsies can be caused by both genetic and acquired factors, interacting with each other in many cases. To date, although we have identified some genes involved in human epilepsy, most of which encode subunits of ion channels, the causes of a large proportion of epilepsies remain obscure. Recent clinical and molecular genetic findings have shown that some of the epilepsies previously regarded as symptomatic were actually idiopathic (genetic), such as severe infantile myoclonic epilepsy (SMEI), most of which are associated with SCN1A gene mutations. On the other hand, with the identification of subtle lesions such as developmental abnormalities of the brain by advanced MRI, some of the "idiopathic epilepsies" actually should be diagnosed as symptomatic. For pediatricians, most of their patients with neurological disease suffer from epilepsy, among whom 1/3 are intractable. To clarify the definite etiology of childhood epilepsy is critical and helpful for early intervention and prevention. Inborn errors of metabolism are rarely found to be the cause of epilepsy, but seizure, especially occurring in neonatal period and infancy, is a common symptom in a great number of metabolic disorders. Inborn errors should be considered as an important possible underlying disease for seizures that are recurrent, status, intractable and epileptic partialis continua, which occur after one year of age and are not associated with fever, central nervous system infection, or trauma. Epilepsies due to inborn errors of energy metabolism (such as mitochondrial disorders and hypoglycemia), substance storage (such as variant lipidosis), amino acids or organic acids metabolism, and neurotransmitter system are not uncommon conditions encountered in pediatric clinics and ward. Among 65 cases of Leigh syndrome di-


The study aims to analyzed and identify the heat transfer characteristics of heating unit for car using experimental method in order to design DPH. The temperature comparison processes were done with various experimental conditions. In addition, the optimal conditions of DPH design were proposed as field test in real car, hot air flow, transient situation.


Iran is one of the most important regions for origin and diversification of wild almond species in the world. Over 20 species, naturally distributed in many regions, have been identified to date in Iran. These can be used as rootstocks in different Prunus species such as almond or peach due to their adaptability to severe (drought) environmental conditions and resistance to some pests and diseases. Results showed that P. eburnea had the most stem biomass, and P. scoparia the least leaf area and the largest root system among the three species, which can indicate better adaptation to drought conditions. The correlations between the measured traits suggest that the relationship between shoot and root morphology is unique for each species. In addition, results indicated that P. eburnea had the highest seed germination percentage and P. elaeagnifolia the lowest. Finally, there was significant difference between wild rootstocks in grafting success, with P. scoparia and P elaeagnifolia showing the best behavior.


The growth rate of the sheet pinch instability is calculated in the small Larmor radius limit using the method of integration along unperturbed orbits. It is found that the instability is driven by a small group of ``resonant'' electrons which cross and drift about the neutral plane having zero velocity along the field lines. The microinstability is absolute and develops fastest for a critical perturbation wavelength, of the order of several times the thickness of the plasma sheet.


To investigate possible extrahepatic sites of SAA production, male BALB/c mice were given a single 0.5 ml injection of either 10% casein or lipopolysaccharide (LPS; 100 mg/ml). Twenty hours after injection, RNA was extracted from liver, kidney, adrenal, testis, brain, spleen, skeletal muscle, heart, lung and small intestine. Northern blots of total RNA were hybridized with nick-translated /sup 32/P-labeled cDNA probes (length approximately 150 base pairs) corresponding to an homologous region of the three known SAA genes. Both casein and LPS elevated the mRNA in liver to about 200-fold above control levels; mRNA was elevated in adrenals from O to approximately 2% of liver. mRNA in some other tissues responded only to LPS injection: levels in kidney reached 15% of liver; pituitary, testis and brain reached 0.02 to 0.5% of liver; no apoSAA mRNA was detected in heart, skeletal muscle, lung, spleen or small intestine. Thus, some organs other than liver appear to have operational genes for apoSAA. The expression of apoSAA genes in different tissues is shared with other apoproteins; it remains to be seen whether all three or only selected genes are transcribed and translated in different tissues.


Recently,scholars focus on the research of the relationship between impoliteness and emotion in the field of pragmatics.This paper aims to investigate the impoliteness in the emotional context from the perspective of cognition and relational management which is put forward by Spencer-Oatey,it inquires the operation of emotion in impolite behavior to proclaim how emotion trigger the impolite behavior and how emotion changes in the production of impoliteness.This paper provides a new angle of view to research the impoliteness from the emotion.


With the increasing complexity and functionality of Real-Time embedded applications, Multiprocessor System-on-chip "MPSoC" offers the best tradeoffs in computation performances and power consumption. Designing MPSoC projects is time consuming and, often requires several competences and steps, spanning from hardware architecture to mapping application on the platform. This paper presents MPSoCDK, an integrated framework for rapid prototyping and validating MPSoC projects targeting FPGA devices. This platform, which includes several environments and toolchains, allows the designer to shorten the process of designing and exploring MPSoC projects, by simplifying the creation, the validation and the exploration of components in the MPSoC platform. Results show that the proposed framework can efficiently speedup the process of exploring, generating and programming multiprocessor platforms using a Graphical User Interface (GUI).


We report the observation of a dipole-bound state (DBS) 659 cm-1 below the electron detachment threshold of cryogenically-cooled deprotonated 4,4'-biphenol anion (bPh-) and nineteen of its lowest vibrational levels. Resonant two-photon photoelectron imaging (R2P-PEI) via the vibrational levels of the DBS display a sharp peak with a constant binding energy. This observation indicates vertical detachment from the vibrational levels of the DBS to the corresponding neutral levels with the conservation of the vibrational energy, suggesting that the highly diffuse electron in the DBS has little effect on the neutral core. The R2P-PEI spectra also exhibit two features at lower binding energies, which come from intersystem crossings from the DBS to two lower-lying valence-bound triplet excited states of bPh-. The current study discloses the first R2P-PEI spectra from vibrational excited states of a DBS and direct spectroscopic evidence of transitions from a DBS to valence-bound states of anions.


PURPOSE: A watch type pulsimeter and an emergency rescuing system using the same are provided to automatically inform information obtained from the watch type pulsimeter to medical treatment centers in case of the occurrence of abnormality. CONSTITUTION: A main body(110) detects and displays the pulse and the body temperature of a user in a measuring mode. A band part(120) is composed to be worn around the wrist of the user. A pulse detecting part detects the pulse of the user using an optical unit and converts the detected pulse. The detected pulse is transmitted to the main body. The pulse detecting part includes a light emitting element(132) and a light guide element(131).


91Background: Performance status (PS) is used to predict tolerance and morbidity associated with CRC treatment. Monitoring activity level at the start of therapy using a wearable fitness tracker Fi...


Inter-turn faults are most likely the initial stator winding fault in variable speed drive systems with Voltage Source Inverters. The machine must stay within its thermal requirements locally at the fault to prevent its propagation. In this paper, we present a fault tolerant control scheme for a double three-phase Permanent Magnet Synchronous Machine which minimizes the propagation of the fault by adapting the operating points of both systems independently. We estimate the generated heat by the inter-turn fault with a machine learning regression. If the estimated heat of the faulty system is greater than a definite value, the operating point of this system is adapted until the estimated heat is below the limit. The healthy system is used to compensate the torque reduction of the faulty system. We validated the concept of the control scheme with a Finite Element Analysis simulation. The presented double three-phase machine can compensate 13.9 W at nominal torque, which is an improvement of 74% compared to the equivalent single three-phase machine with the same heat limitation strategy. This heat reduction equals a temperature reduction of 111.2 K at fault locally.


Authentication is critical for any digital system as it represents the first step towards accessing data and resources. Authentication of entities, especially devices in the Internet-of-Things (IoT) system, is one of the most important security challenges that needs to be addressed; otherwise, it will hinder the deployment of IoT applications. The most widely used authentication mechanisms in IoT are based on one-factor cryptographic techniques. These techniques are often not sufficient in the context of IoT due to the limited computational power of IoT devices and the severity of security concerns, especially that these devices are physically not well protected. Consequently, any weakness in the identification/authentication schemes would allow a compromised entity to perform dangerous attacks. To overcome the above-mentioned limitations and achieve high authentication accuracy, we propose an efficient two-factor lightweight mutual authentication scheme for IoT entities, which can be deployed at various levels; device, control, aggregation node, gateway, and server. The first factor is based on a cryptographic protocol which employs a configurable Physically Unclonable Function (PUF) along with a nonce extracted from the physical channel. The second factor is an entity-based fingerprint that uses specific information (i.e., features that can be extracted from various layers of the communication protocol) to construct a unique fingerprint for each entity. The proposed scheme is designed to require the minimum possible overhead in terms of computation and communication overhead, and ensure maximum security resilience against authentication attacks.


A b s t r a c t: Bacteriocins active against Listeria monocytogenes produced by Leuconostoc mesenteroides E131 and Lactobacillus sakei I154 isolated from Greek and Italian traditional fermented sausages, respectively, were studied. The bacteriocins were purified by 50% and 70% ammonium sulphate precipitation, by cation exchange, and reverse phase chromatography. Bacteriocins were active at pH values between 4.0 and 9.0 and bacteriocin from Lc. mesenteroides E131 retained activity after incubation for 1 h at 100oC, while bacteriocin from L. sakei I154 retained activity even after incubation for 15 min at 121oC with 1 atm of overpressure. Inactivations by enzymes were variable.


A switched reluctance motor control system for coal gangue hoist is presented. It is a non-linear system. A fuzzy controller is developed to improve performance of the hoist. This system features good robustness.


The general presumption is that the informal economy more specifically Motor Cyclist plays a very critical role in ensuring the resilience o f Nigerian econo my. However, the extent of its impact as well as its contribution to em- ployment generation is largely unknown. It is in the light of this that the paper examines the impact of Motor Cyclist on emp loyment generation in Northern Nigeria. Data were collected fro m 250 Motor Cyclist in selected State of Northern Ni- geria using mult i - stage sampling techniques. The results of the analysis indicate that wages and profits are not important in the determination of labour employ ment in the Motor Cyclist due to informality of the business, but investment is sig- nificant and important toward labour demand. The results also indicate that a positive relationship exist between employers wage with wages of other firms (co mpetitors), experience and profit. More so, the study finds out generally that Motor Cy- clist has contributed to employ ment generation in Northern Nigeria. The study, therefore, recommended the need for ade- quate credit facilit ies, infrastructures, establishment of train ing school for Motor Cyclist. 1. Introductions The informal sector refers to that part of the economy which does not fall under the purview of organized history. As the concern of the world co mmun ity increased over lack of economic g rowth and perpetration of poverty in the de- veloping countries, policy makers began to look fo r solutions to save the situation. The traditional wisdom of economic development, represented by Prebisch's doctrine of Post - Keynesian development suggests that what is needed is appropriate macro - economic policies and institutions, together with sufficient funds. A planned promotion of growth in selected leading sectors of the economy would then lead to the overall g rowth of the economy. The primary problems were perceived to be the identification of the target sectors with maximu m linkages to the rest of the economy and the mobilizat ion of finance to enhance the growth rate of the target sectors. (CBN, 2001) The informal sector encompasses largely unrecognized, unrecorded and unregulated small - scale activ ities. It in- cludes small enterprises with h ired workers or household enterprises using family labou r and the self-emp loyed. Production processes characteristically rely on high levels of working cap ital as against fixed capital. Formal contracts between employers and employees or between buyers and


By far the largest part of the book is devoted to the reign of Victoria. The reasons for this are obvious. Many questions in which the monarch and cabinets differed came to the front in the reign of the queen; and with the continuous movement in Great Britain towards democracy, ministers became more insistent that power must rest with the cabinet, because the transfer of power from the crown to the cabinet was in accord with their conception of government by Parliament, and because they realized that the constituencies would support them in this position. Another obvious reason for the detail that characterizes the treatment of this reign is the existence in print of the queen's letters of the period from 1837 to 1861, and the ample proportions of the published letters and memoirs of nearly all the statesmen of the Victorian era. Excellent use has been made of all this material by Mr. Farrer, and of similar material of the reigns of George III, George IV and William IV. Mr. Farrer has drawn singularly little on the writings of the constitutional historians. He makes no mention, either in the text or in the bibliography, of the noteworthy series of articles on the crown and the cabinet that Dunckley, under the nom de plume of Verax, wrote for the Manchester Weekly Times, when the third volume of Martin's Life of Prince Consort was published in 1878, articles that were republished in book form in the same year entitled Letters of Verax. Moreover, he seems unaware that in some histories of the house of commons considerable attention has been bestowed on the crown in politics. It is like looking a gift horse in the mouth to suggest shortcomings in Mr. Farrer's book; for it is an unusually interesting book on an exceedingly interesting subject, and a noteworthy contribution to the history of the relations of the crown and cabinet from 1760 to the end of the nineteenth century.


The more sophisticated the technology, people can send or exchange messages to convey or send important information easily. Messages that are confidential or not will be sent to the recipient of the message, but messages made using the TXT can be replaced and damaged by irresponsible parties. There is a lot of knowledge in securing files that are used at this time including compression, cryptography, and steganography. The cryptographic algorithm used is Advanced Encryption Standard (AES-128), Ziv Welch Lemp compression algorithm (LZW) and End of File (EOF) steganography algorithm. In the research that will be carried out LZW Algorithm will do the txt data compression process. After that the compression results will be encrypted using the AES method and the last is to insert the encryption results into the bmp image using the EOF method. The results of testing in this study LZW, AES and EOF methods were successfully implemented when tested one by one, but could not be implemented properly when all of these methods were combined when tested. Where the data from the seven test data used are only two data that were successfully tested.


In this study the concentrations of trace elements such as lead, cadmium, iron, nickel, copper and zinc in the human semen (n = 47), occurrence of pathological spermatozoa, and correlations of these elements to pathological forms were investigated. For each sample of human spermatozoa at least 500 spermatozoa were evaluated. Metal contents were determined by the voltametric method and flame absorption spectrophotometry method. The concentrations of trace elements in human semen were: lead 1.49 ± 0.40 mg.kg− 1, cadmium 0.13 ± 0.15 mg.kg− 1, iron 2.59 ± 0.21 mg.kg− 1, nickel 0.40 ± 0.07 mg.kg− 1, copper 0.28 ± 0.06 mg.kg− 1, and zinc 153.93 ± 67.08 mg.kg− 1, respectively. The total percentage of pathological spermatozoa was 41.61 ± 9.80% with predominancy of broken flagellum, flagellum torso and separated flagellum. In relation to trace elements the analysis showed correlation between copper and lead (r = −0.47), nickel and iron (r = 0.36), lead and flagellum ball (r = −0.39), cadmium and large heads (r = 0.37) and between iron and other forms of pathological spermatozoa (r = −0.32). Results of this study describe possible effects of trace elements on the spermatozoa quality in normal human sperm.


Static-power-based side-channel attacks have developed rapidly in the past few years. Many classical side channel attack algorithms have been adapted to exploit static power consumption. There have been successful applications of side-channel attacks based on static power dissipation of cryptographic circuits designed in different technology sizes. In this paper we perform template attacks on a masked s-box circuit designed and simulated using 45-nm CMOS standard cell library. We are the first to compare template attacks using static power and dynamic power in the context of masked sbox implementations. We are able to achieve successful results using both types of power leakage. However, we observe that, in the 45-nm environment, dynamic power analysis requires a high sampling rate for the oscilloscopes used to collect data, while the results of static power analysis are more sensitive to additive noise.


Americans are too busy to cook at home.They often eat outside.Eating culture is one of the important parts in America.There are many kinds of restaurants.Some are open for breakfast. Others are open twenty-four hours a day. A number of restaurants call themselves"family restaurants".They serve no alcohol~* and have fairly restricted~* menus.They serve steaks,hamburgers and sandwiches.Besides these,there are some special restaurants.They serve only or mainly steaks,seafood,etc.


The American Committee for Protection of Foreign Born was a Communist-affiliated legal advocacy organisation that operated from the 1930s through to the 1970s, that witnessed several periods of ideological and social change in immigration policy and politics. As a radical campaign group, it developed as an outgrowth of the twentieth-century American left, and created a distinct platform devoted explicitly to defending the rights of immigrants. Using the courts, popular protest, policy advocacy and other innovative campaign strategies, the group and its regional affiliates, along with allied leftist organisations, pioneered a framework of constitutional rights and legal protections for the immigrants who were persecuted and threatened with deportation due to their links to the labour left. During the early Cold War, their work defending foreign-born radicals against deportation gradually expanded to include other immigrant communities, and to broach broader issues of civil and human rights.


ABSTRACT Places that are both recovering from violent conflict and dependent on natural recourses face the overlapping challenges of reducing the risk of recurring conflict, promoting economic recovery, and ensuring sustainable environmental management: all challenges exacerbated by climate change. This article examines how climate change alters conflict outcomes and vulnerability in Karamoja, Uganda, a region recovering from decades of intense violence. Drawing upon structured interviews with local government officials, direct observation, semi-structured interviews, and a document review, I demonstrate that while Karamoja has stabilized following a region-wide disarmament, the impacts of climate change, when taken in combination with region-wide changes in land use, have contributed to new forms of localized conflicts including resource-related conflict, theft, and intrahousehold violence. This case, therefore, demonstrates how the cycle of increased vulnerability to climate change due to conflict and increased conflict risk due to low adaptive capacity represents a dangerous and reinforcing feedback loop. Moreover, though climate change is affecting conflict outcomes in Karamoja, those outcomes are far less severe than the region's past, non-climate-related conflicts. That raises complex questions about how to conceptualize the significance of climate change as a driver of conflict and underscores the need to reconceptualize climate-conflict beyond simply questions of causality.


The main purpose of this study is to find empirical evidence of the effect of Management Accounting Information System application toward resulted information quality, the effect of information quality on good government governance (accountability, transparency, participative), and the direct effect of Management Accounting Information System application on good government governance. Meanwhile, the special purpose of this study is to find the indicator of the success of Management Accounting Information System application, the indicator of qualified information, and the indicator of accountable, transparent, and participative government at local government in Lampung, Indonesia. This study uses survey method with descriptive and verification approach in the population of all regional Working Organization (Organisasi Perangkat Daerah / OPD) in districts/cities in Lampung, Indonesia, by using primary data through questionnaire distribution. Data analysis uses SEM Partial Least Square (PLS). The result of this study gives empirial evidence that the application of management accounting information system positively affects information quality of management accounting. Moreover, information quality of management accounting positively affects Good Government Governance. In this case, information quality of management accounting is proven playing role as mediating variable between variable of Management Accounting Information System (MAIS) application and Good Government Governance (GGG). However, there is no direct effect of MAIS application of GGG which is accountability, transparency, participation. The limitation of this research is limited population in lampung province since this research uses questionnaire as primary data. The practical implication of this result is that government is expected to be able to improve and apply the right policy to overcome the weaknesses in regional MAIS application in order to increase resulted information quality and eventually would affect good government governance. MAIS can affect GGG directly or indirectly via information quality as mediating variable.
Index Terms— Accountability, Information quality, Management accounting information system, Participative, Transparent.


The emerging theme of the session was "start with the end in mind". Presenters and delegates considered the strategies between what to file (and what not to file) and the risks associated. Matt Dixon talked about the importance of developing an IP strategy and the fact that this needs to be tailored to the case and the market. He described the risks that may be associated with filing strategies and encouraged analysis before and during prosecution. A lot of money can be wasted with poor choices in international patent filing and Matt showed some interesting data on where markets may lie which helped inform choices in filing territories. Mark Anderson emphasised the importance of considering downstream consequences of IP as part of collaboration agreements. Disputes over IP can be extremely expensive, so it is best to have clear, simple, robust ownership and commercialisation arrangements. Negotiating IP terms in collaborations requires careful thought and drafting but it is also important to consider what will happen during the research and patenting phases. Sometimes IP terms are too theoretical and don't take account of the practicalities. Whilst joint ownership of Foreground IP is a possible solution, Mark cautioned against this and explained that whilst simple and fair to the inexperienced, it requires much more drafting than other ownership arrangements. Neil Bradshaw talked about IP as a strategic tool and discussed the Easy Access IP initiative which has been adopted by a number of universities (UK and overseas) who see the value in an overt open innovation approach. He reminded us that the point of the initiative was to license some IP for free to stimulate innovation and collaboration and he explained that industry has been very receptive to the proposition and it hasn't compromised negotiating conventional licences and contracts. But it was agreed that it will take a couple of years to bed in before there is a suite of case studies available but early signs are that new industry-university relationships are being formed.


FIELD: medicine, virology, pharmacy. SUBSTANCE: composition has 2 1 ,3 1 -deoxypurine nucleoside as an active component taken from the group involving 2 1 ,3 1 -deoxyadenosine, 2 1 ,3 1 -deoxyinosine and 2 1 ,3 1 -deoxyguanosine and/or their pharmaceutically acceptable salts and/or their hydrates and water-insoluble antacid buffer system and special additions. Buffer system provides pH value in stomach about 5 and consists of water-insoluble antacid compound of magnesium in combination with sodium dihydroxyaluminocarbonate at mass ratio = 1:(2-4) or in combination with calcium carbonate at mass ratio of magnesium compound and calcium carbonate = 1:(1.5-3), respectively. Mass ratio of 2 1 ,3 1 -deoxypurine nucleoside and special additions in combination with buffer system = (0.005-0.375):(1.9-6), respectively. Composition is prepared as tablet or powder for preparing the dispersion in liquid. EFFECT: enhanced biological availability of an active component. 7 cl, 3 tbl


This report gives an overview of the national Intelligent Transportation Systems (ITS) efforts introduced through the 1998 Transportation Equity Act for the 21st Century (TEA-21). It focuses on several ITS projects in both rural and urban areas and describes legislation relating to the topic. Subjects addressed include TEA-21 provisions, ITS integration, the commercial vehicle program, traveler information, rural ITS applications, and other state action.


High-speed imaging of the larynx provides a valuable means for studying vocal folds function and vibratory behaviors. Using laryngeal high-speed videoendoscopy (HSV) with a flexible nasolaryngoscope, one can record the detailed vibratory movements of vocal folds during connected speech. This high-speed imaging tool enables us to study the normal function of the vocal folds and how this function can be disrupted due to the presence of voice disorders. In this work, HSV data were utilized during connected speech from subjects with normophonic voices (no voice disorders) and a neurological voice disorder. The data were obtained using a high-speed camera, coupled with a flexible endoscope, at 4,000 frames per second. Deep learning was used for the analysis of the big HSV dataset to extract the vibratory behaviors of the vocal folds. This deep-learning-based tool achieved high levels of accuracy for analysis of challenging HSV data in connected speech. This tool provides a computationally cost-effective and an accurate measurement approach that could help design more advanced voice assessment protocols in future.


Dear Dr. Wu et al. Thank you very much for your interest in our study. While the reference population used in our evaluation differed from yours, we believe that Harrington et al. also used nongerminal center B cells as their reference population, insofar as we interpret their wording, "Antigen expression patterns were compared with those of normal, polytypic B cells" (1). In our experience, it was unusual to see residual non-neoplastic germinal center B cells in our lymphoma samples. However, most cases contained resting polytypic CD10-negative B cells, and we chose this as a reference population as it seemed to us to be desirable and more practical to use an internal, rather than external, reference for as many cases as possible. Had we used germinal center B cells as a reference population, it is possible that we may have gained some sensitivity for the detection of dim CD20 staining in double-hit lymphoma, but it is likely that we would have lost some specificity as well, as we would have used the same standard for our "control" cases of Burkitt lymphoma and diffuse large B-cell lymphoma, subtypes that were not included in your analysis. We did not consider expression of CD38 by lymphoma cells in our analysis, as our study was retrospective in nature (similar to yours) and we do not include CD38 in our routine analysis of mature B-cell populations. However, we do not think that this would have limited our ability to identify double-hit lymphomas, because our cases were identified initially by cytogenetic analysis demonstrating concurrent rearrangements involving MYC and BCL2 or BCL6. Further, we note that in your original analysis of 10 cases, only four showed increased expression of CD38, while the remaining six showed normal or decreased expression of CD38, as indicated in Table 2 (2). We agree that our use of CD20-PerCP (vs. CD20-V450 used in your study) is a methodological difference that may have contributed to the different conclusions reached by our two groups. However, the issue of methodological differences between the three studies contributing to differences in the findings was one that we discussed at some length in our article (3). Ultimately, we believe that if the detection of dim CD20 expression in double-hit lymphoma requires a relatively specific set of conditions in terms of platform, antibody panel, fluorochrome, and reference population, the most obvious conclusion (and one also emphasized in our article) may well be that this finding is not generalizable across different laboratories and that caution should be used in relying on it to suggest a diagnosis of double-hit lymphoma (3). That being said, we should point out that we found an important similarity between our work and that of Harrington et al. in that dim expression of both CD19 and CD20 showed very high specificity (i.e., was 100% specific) for the diagnosis of double-hit lymphoma (1,3), suggesting that the methodological differences in our approaches may not have been so great as to prevent arrival at similar conclusions, if those conclusions were strong enough to be supported by different sets of data.


To shed some light on the problem of the most likely architecture, island or archipelago, of the polycyclic aromatic hydrocarbon (PAH) core in asphaltenes, molecular orbital (MO) calculations have been carried out considering two PAHs per asphaltene molecule cross-linked (archipelago model) and the same two PAHs aggregated in a parallel fashion and not cross-linked (island model of interacting PAHs). The calculated highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gaps (H―L gaps) are compared to the 0―0 band experimental fluorescence emission data of asphaltenes. The calculations of the H―L gap were performed at the semi-empirical ZINDO approach using density functional theory (DFT) dimer-optimized structures (relaxed structures). This methodology was validated against experimental data and it was proven to have a good predictive power. A total of 48 PAHs with 5―10 fused aromatic rings (5FAR―10FAR) were calculated, as well as all of their possible combinations in dimers formed by large core (5FAR―10FAR)―large core (5FAR― 10FAR) systems (large―large core dimers). In total, 1176 systems in the archipelago architecture, crossed linked with a C 5 alkane chain, and 1176 systems in the island-stacked interaction were calculated. Also, island and archipelago models were constructed with the 48 PAHs, interacting in both architectures, with 10 PAHs that contain 1―4 fused aromatic rings in the structure (1FAR―4FAR), thus comprising 960 calculations of large core (5FAR―10FAR)―small core (1FAR―4FAR) dimers (large-small core dimers). Therefore, a total of 3312 systems are calculated in this work. For both cases, large-large and large―small dimer systems, and for both architectures, island and archipelago, statistical analysis of the results was carried out. It is found that the calculated H―L gap of the dimers with the archipelago architecture is similar to the H―L gap of the monomers. For the case of the island dimers (stacked dimers), there is a dependency of the H―L gap upon both the size of the monomers, in terms of the number of fused aromatic rings, and the type of interlayer geometries or stacking arrangement between the monomers composing the island (stacked) dimer. The stacked dimers are more stable in most of the cases than the archipelago dimers. The higher stability in turn produces larger H―L gaps. The remarkably broad variation of the energy gap, of 0.9 eV, between the island and archipelago architectures for the large―large dimers strongly depends upon the dimer size and the stacking arrangement. In the later, the π―π interactions play a role but have a minor influence. The stacked island systems that fall inside the experimental range of asphaltenes are, in general, dimers composed with the same monomer in hexagonal (H) arrangement and 6FAR―10FAR combinations with parallel displacement (PD) arrangement, mainly without fjords or coves in the structure. Of all of the PAH systems that fall inside the experimental range of asphaltenes when interacting with any other PAH, to form a dimer, in either island or archipelago architecture, the 7FAR PAHs are more abundant in agreement with the former literature. When the percentage of all the calculated dimers, large-large and large―small, is compared, in both architectures, and whose H― L gap falls inside the experimental asphaltene fluorescence range, the large―large dimers are more abundant than the large―small dimers. The large-large dimers are more abundant by 20.6% in island architecture, and by 17.9% in archipelago architecture. It is concluded that indeed, if two asphaltene core PAHs are directly bound via a single bond, then optical methods, such as time-resolved fluorescence depolarization (TRFD) studies, would identify this as a single chromophore, thereby blurring the distinction between island versus archipelago. Some decomposition studies might find this single-bonded pair of PAHs as a single entity as well.


Maps ... are superimposed in such a way that each map finds itself modified in the following map, rather than finding its origin in the preceding one: from one map to the next, it is not a matter of searching for an origin, but of evaluating displacements. Every map is a redistribution of impasses and breakthroughs, of thresholds and enclosures, which necessarily go from bottom to top. There is not only a reversal of directions, but also a difference in nature: the unconscious no longer deals with persons and objects, but with trajectories and becomings.... --Gilles Deleuze (1) Disclaimer experiment, n. The action of trying anything, or putting it to proof; a test, trial; (2) the following article. The beautiful thing about the hard sciences (e.g., chemistry, physic, etc., and I mean no disrespect to those fields that fall outside of the common designation "hard sciences"), is the experiment. Or rather, more wonderful than even the experiment is the inherent acknowledgement that the scientist begins with only a hypothesis and that the evidence gathered sculpts the hopefully-publishable paper. The scientist cares not what path the evidence takes him or her, or whether or not his or her hypothesis was right in the first place. A successful scientist gets paid to evaluate the differences in his or her findings with the scientist's hypothesis. Scientists must reconcile each turn within a rhizome. This is the Scientific Method, the dominant form of scientific inquiry for five hundred or so years. This paper is an experiment testing a two-fold hypothesis. The two hypotheses are as follows: 1) a modified Scientific Method can be used effectively to conduct research in the field of English Literature, Critical Theory (Cultural Studies) and Human Sciences (as well as, I presume, every other social science) 2) this paper, which is an inquiry on maps will, in fact, function as a map. The two hypotheses may, however, be in fact one. A paper which acts like a Deleuzean map has similar properties to that of the Scientific Method: observation, hypothesis, experiment, conclusion. I, however, do not want to spend my time on this paper trying to employ the strict Scientific Method or trying to show similarities to it. I invoke the Scientific Method for the possibility it presents. Basically every paper in the field of English Literature has an observation, hypothesis (thesis), experiment (evidence) and a conclusion (they already resemble the Scientific Method). But how often does the writer prove his or her hypothesis incorrect? Never (or at least I have never encountered this). My aim in this paper is to 'experiment' with a new method of inquiry. This inquiry works like a Deleuzean map. Method of Inquiry I will describe this paper as a series of displacements. I am beginning the paper with the above quote from "What Children Say." This is the observation (or Deleuze's observation). I will then hypothesize about this quote. It is the experiment that will seem extraordinary. Each piece of new evidence will take the paper in a different direction. After each piece of evidence is introduced, it will be my job to draw conclusions about the displacement. This conclusion is only meant to be a conclusion to one part of the whole rhizome (whose nature is infinite). Let me put it more simply, I am following one possible path this paper could take. This will be only one of the many possible papers produced. This paper may be continued ad infinitum, either from the 'end' of this paper, or from any point within it. I hope this will give you some idea as to how this paper will work, but I hesitate to explain any more, for I want to leave the possibilities as open as humanly possible. A becoming-rhizome is what is desired for this paper. Mapping Maps To begin this first section, I hesitate to copy the exact same quote that this paper started with, but I feel as though, even though these are the exact same words, when superimposed on the first, they will have a different ring to it because of the displacement that occurred from the start of the paper to this point: Maps . …


We leverage the attractive properties of a high χ–low N BCP, i.e., poly(styrene)-block-poly(2-fluoroethylmethyl acrylate) (PS-b-P2FEMA), and illustrate its utility for next-generation nanomanufactu...


In recent days, the most of the people uses LPG and Induction stove. But in this way, the cost of cooking is high. On the another side, in village areas, people mostly uses wood stove. In the normal wood stove, combustion of wood is incomplete, cooking takes long time. To get complete combustion of wood and reduce the cooking time, the air compressor is included. The air compressor is powered by solar panel and battery. In day time, the compressor is powered by using the renewable energy system like PV Panel and charges the battery. In night time, the compressor runs with the use of battery. The model of the solar powered low cost compressor for domestic wood stove is described in this paper.


Combining Carbon Capture and Storage (CCS) and Geothermal energy has technical, economic and social benefits. In Europe, there is potential for this synergy. Overlapping data from CO2 storage assessments and geothermal data of EU regions give us an overview of the zones where this combined technology can be developed.


Digital Production Line Design and Simulation is a practical and comprehensive major course for electromechanical and automation majors in higher vocational colleges. This course is based on digital technology to construct automatic production lines, and uses virtual simulation and virtual reality combination technology for teaching, creating a new digital teaching ecology. In this paper, the teaching innovation means and methods are proposed, and specific exploration and practice are carried out for this course, which has achieved good teaching results.


Maybe not such a global appraisal of State aid after all: CJEU backtracks from a truly economic approach (C-124/10)* In an interesting recent paper, Pablo Ibanez Colomo conducts a very detailed…


Background Positron emission tomography (PET) findings for gliomatosis and lymphomatosis have been rarely reported. Purpose To compare PET/computed tomography (CT) findings using 11C-methionine (MET) from PET/CT findings using 18F-fluorodeoxy glucose (FDG) for patients with lymphomatosis or gliomatosis of the brain. Material and Methods Participants comprised all 10 patients with lymphomatosis or gliomatosis of the brain treated at our institution in the past 12 years. Underlying pathologies comprised intravascular lymphoma (n = 1), lymphomatosis (n = 3), and gliomatosis (n = 6). All cases were pathologically diagnosed. In seven patients, both MET-PET/CT and FDG-PET/CT were performed simultaneously in a single study. In three patients, only FDG-PET/CT was performed. The degree of tracer accumulation to the lesion was evaluated qualitatively. Quantitatively, the ratio of maximum standard uptake value (SUVmax) in tumor to that in normal tissue (T/N ratio) was measured and compared between FDG and MET. Results Qualitatively, MET accumulated to part of the lesion in six of seven patients and almost all of the lesion in one in seven patients. FDG accumulated to part of the lesion in three of ten patients and almost all of the lesion in one of ten patients. No FDG accumulation was seen in the lesion in six patients. Quantitatively, mean ± SD T/N ratio was significantly higher with MET (2.11 ± 0.63) than with FDG (1.18 ± 0.84; P < 0.05, Wilcoxon signed-rank test). Conclusion In lymphomatosis and gliomatosis, FDG accumulates in only part of the lesion. FDG is thus less suitable than MET for depicting these lesions.


The Taguchi capability index C_(pm) has been proposed to the manufacturing industry for measuring manufacturing capability. Investigations of the estimated Taguchi capability index based on subsamples have been proposed and arrested substantial research attention. In this paper, investigation based on subsamples is considered for normally distributed processes from the traditional distribution frequency approach. A reliable inferential procedure based on subsamples of the estimated Taguchi capability index is proposed. Computational programs using Matlab software are proposed to calculate p-values and critical values required to ensure the process reaching a certain desirable level of the time. A practical example is provided to demonstrate how the proposed procedure may be applied for judging whether the process runs under the desirable quality requirement.


Summary The regulation of granulocyte‐colony stimulating factor (G‐CSF) and interleukin‐6 (IL‐6) mRNA was studied in human adherent monocytes in response to the protein kinase C activator, oleolyl‐acetylglycerol (OAG), the calcium‐ionophore A23187 and the cyclic AMP elevating agents, dibutyryl c‐AMP (DBcAMP), cholera toxin and isobutyl‐methylxanthine (IBMX). G‐CSF and IL‐6 transcripts were simultaneously expressed in response to OAG, A23187, DBcAMP, IBMX and cholera toxin. However, the time course demonstrated a difference; a rapid induction by OAG and A23187 and a delayed pattern by cAMP elevating agents. In addition it appeared that the induction of CSFs by DBcAMP was independent of the adherence procedure or the presence of fetal bovine serum but could be counteracted by the simultaneous addition of H8, an inhibitor of the cAMP dependent kinases.


This paper studies a two-variable Laurent polynomial invariant of regular isotopy for classical unoriented knots and links. This invariant is denoted LK for a link K, and it satisfies the axioms: 1. Regularly isotopic links receive the same polynomial. 2. Lo0=1. 3 L _ = aL, L_? = a-'L. 4. L ) Small diagrams indicate otherwise identical parts of larger diagrams. Regular isotopy is the equivalence relation generated by the Reidemeister moves of type II and type III. Invariants of ambient isotopy are obtained from L by writhe-normalization.


It is now ten years since the Member States of the European Union signed the Treaty establishing a Constitution for Europe. The Treaty, which was subsequently rejected in referendums in France and the Netherlands, ultimately inspired the Treaty of Lisbon, which entered into force in December 2009. In a discussion with EUROPP's editor Stuart Brown, Lord Kerr of Kinlochard, the Secretary General of the European Convention which produced the Draft Constitutional Treaty, discusses the failures of the process, the impact on the Commission, and the attempts to reform the UK's relationship with the European Union currently being pursued by David Cameron.


Objective: Aboriginal and Torres Strait Islander people experience adverse health outcomes and have high rates of smoking and related illnesses. This brief report describes stress as a barrier to quitting smoking derived from reflections within an Aboriginal Medical Service and makes recommendations for intervention development.


The Submillimeter Technology Laboratory(STL) at the University of Massachusetts Lowell has developed a methodology of tailoring the complex refractive index for artificial dielectrics at terahertz frequencies. A wide range of precisely controlled optical properties have been achieved for materials such as vinyl acetate, silicone, polyethylene and epoxy resin when combined with powdered loading agents such as boron nitride, silicon, graphite, iron oxide and stainless steel flake. Using this technology, STL has successfully fabricated both narrow-band and wide-band anechoic structures. The method of characterizing materials for the purpose of tailoring their dielectric properties at terahertz frequencies is presented along with several demonstrated applications. 2. Introduction Because of the increase in the number of optical and quasi-optical measurement systems operating at terahertz frequencies, new materials providing alternative solutions to the design of system components are required. In response to this, STL's recent activities include an aggressive program to evaluate a wide range of materials for terahertz frequency applications(1-3). Using inhouse expertise in the technique of tailoring artificial dielectrics and the polarimetric characterization of materials, a variety of composite structures have been created as far-infrared radiation absorbing material (FIRAM)(4,5). metal substrate dielectric layer { { incident radiation


In the overall context of national transport in Italy the road plays such an important part that it is of paramount consideration in any planning or programming of mobility. In this article separate chapters review: traffic movement in Italy; evolution of the role of the highway; transport as a system; traffic and national legislation; and highway financing. (TRRL)


Smart phones have become ubiquitous in the recent years, which opened up a new opportunity for rediscovering the Experience Sampling Method (ESM) in a new efficient form using mobile apps, and provides great prospects to become a low cost and high impact mHealth tool for psychiatry practice. The method is used to collect longitudinal data of participants' daily life experiences, and is ideal to capture fluctuations in emotions (momentary mental states) as an early indicator for later mental health disorder. In this study ESM data of patients with psychosis and controls were used to examine emotion changes and identify patterns. This paper attempts to determine whether aggregated ESM data, in which statistical measures represent the distribution and dynamics of the original data, are able to distinguish patients from controls. Variable importance, recursive feature elimination and ReliefF methods were used for feature selection. Model training and tuning, and testing were performed in nested cross-validation, and were based on algorithms such as Random Forests, Support Vector Machines, Gaussian Processes, Logistic Regression and Neural Networks. ROC analysis was used to post-process these models. Stability of model performances was studied using Monte Carlo simulations. The results provide evidence that pattern in mood changes can be captured with the combination of techniques used. The best results were achieved by SVM with radial kernel, where the best model performed with 82% accuracy and 82% sensitivity.


Specialty is the carrier to implement concretely the talent training in vocational institutions, how to set up specialties is an important issue of the survival and development of higher vocational colleges. this paper, combining with the professional building of Guangdong Traffic Vocational and Technical College, introduces a "Chain of - concentration-style" model with strong characteristics which is suitable for professional building of Industry Higher Vocational Colleges. This paper explores its connotation, significance, setting -up process and a number of key issues, and makes a summary to the effectiveness of their implementation.


Ethyl tert-butyl ether (ETBE) is an alternative fuel oxygenate that can be produced in the liquid phase by addition of ethanol to isobutene catalyzed by sulfonic acid ion exchange resins. A generalized Langmuir-Hinshelwood rate expression is formulated in terms of the liquid phase activities of the reactants that is quasi-autocatalytic due to ethanol. This microkinetic model is combined with the generalized Maxwell-Stefan equations for a detailed investigation of the influence of multicomponent mass transfer limitations inside the macropores of the heterogeneous catalyst. The model is used for revision of experimental rate data for ETBE synthesis in the literature. The analysis reveals that reverse diffusion of isobutene can occur by strong interaction with ethanol and the catalyst effectiveness factor can exceed unity


In LSS staff´s work with autism they relate daily to the international diagnostic manual (DSM) where the American Psychiatrich Association has categorized and globalized the diagnostic criteria. The work has been debated and criticized by social anthropologists as an expression of society's need to categorize, to medicalise suffering and to globalize western expression of suffering. Every day LSS staff face people who have been diagnosed and have access to the support along the clinically assessed needs and what is interesting to watch is how the LSS staff perceive the diagnosis and what they see are the effects for the individual who has been diagnosed with Aspergers syndrome in adulthood. By presenting the anthropological study of diagnosis and by giving a background about previous research and DSM's history, I have received an analyzed LSS staff's response, via a qualitative interview work, with an anthropological view about the subject but also analyzed their experience using Antonovsky's SOC theory. It quickly became apparent that although the anthropologists is pointing to an over establishment of the diagnosis, it helps people that get Asperger's syndrome as adults to obtain a diagnosis as it means support under LSS-law and that LSS staff was positive that these people received their diagnosis as a mean for a better life. (Less)


The horizontally-scanning charge exchange analyzer on the Princeton Large Torus (PLT) was used to measure fast co-moving ions during counter-injection of neutral beams. The large flux of charge exchange neutrals observed under these circumstances exhibited a sharp cutoff as the analyzer was moved toward more parallel radii of tangency. At a fixed angle and beam energy, the cutoff showed a strong dependence on the plasma current. Monte-Carlo calculations using a Fokker-Planck formalism and full toroidal geometry give substantive agreement with the experimental data, indicating that neoclassical effects on neutral beam injected ions were directly observed.


The P450 26 family is believed to be responsible for retinoic acid (RA) metabolism and elimination in the human fetus and adults. CYP26A1 and CYP26B1 mRNA is expressed in tissue specific manner and knockout mice of the CYP26 isoforms show distinct malformations and lethality. The aim of this study was to determine differences in CYP26A1 and CYP26B1 regulation and expression. Analysis of CYP26A1 and CYP26B1 expression in a panel of 57 human livers showed CYP26A1 being the major CYP26 isoform present in the liver and its expression being subject to large inter-individual variability between donors. CYP26A1 and RAR β were found to be greatly inducible by RA in HepG2 cells, whereas CYP26B1, RAR α and RAR γ induced to a much lesser extent. Based on treatments with RAR isoform selective ligands, RAR α is the major isoform responsible for CYP26A1 and RAR β induction in HepG2 cells. Classical P450 inducers did not affect CYP26 transcription whereas PPAR γ agonists, pioglitazone and rosiglitazone, up-regulated CYP26B1 transcription by as much as 209 ± 80 –fold and CYP26A1 by 10-fold. RAR β was also up-regulated by pioglitazone and rosiglitazone. CYP26B1 induction by PPAR γ agonists was abolished by the irreversible PPAR γ antagonist (GW9662) whereas RAR β and CYP26A1 induction was unaffected by GW9662. Overall, the results of this study suggest that CYP26B1 and CYP26A1 are regulated by different nuclear receptors resulting in tissue specific expression patterns. The fact that drugs can alter the expression of CYP26 enzymes may have toxicological and therapeutic importance.


Recently an increased number of electrical devices are being used in automobiles to upgrade their performance and safety. The spatial allowance for the engine compartment is being reduced year after year due to changes in vehicle design and the necessity of securing a safe space. Under the above circumstances, customer needs for downsizing relay boxes are also increasing. In the relay box, fuses and relays that turn on/off electrical circuits are densely integrated. A photo of a relay box and its performance are shown in Fig. 1.


Resin bonded bridge (RBB) is a conservative, medium to long-term restoration of missing teeth. A high rate of debonding was the main limitation in a clinically demanding situation. Objective: To highlight the critical evaluation in identifying the contributing factors leading to the failure of RBBs and avoiding as well as controlling such factors optimally prior to providing further rehabilitative treatment. Case report: This case illustrates a young patient who received resin bonded bridges to replace her missing lateral incisors. Unfortunately, she had issues with bridge debonding, in which one of the abutment teeth was extracted due to caries under the retainer. The patient was then treated with multiple cantilever bridges to restore the missing dentition after optimising the risk factors. Conclusion: With an improved understanding and material advancement, RBB survival tends to be longer nowadays. As it was conservative, in the incidence of failure, other treatment options remain open. However, each failed case should undergo a critical evaluation of the failing aetiology and its mechanism to prevent future occurrences.


that thus far a "Europe-centered" historiography has obscured the internally generated factors in the Balkan awakening, while overemphasizing the impact of foreign influences (both political and cultural). In Turczynski's view, the primary source of sociopolitical dynamics was the deep tension generated between the traditionalist tenets of Orthodoxy and the innovative demands of Habsburg imperial policies. Particularly emphasized is the role of the Orthodox hierarchy in delineating the "confessional nationality" of both Serbs and Rumanians during the eighteenth century. In the structural sense, Turczynski sees an overlapping series of phases of mounting national consciousness taking place among both peoples after their partial incorporation into the empire during the late seventeenth century. The approximate sequence was (1) a "prenational socialization," extending into the middle of the eighteenth century; (2) a gradual catalyzation of "confessional nationality" after about 1740 via the reaction of the church hierarchy to the prejudice and civic disabilities to which they and their flock were exposed; (3) the transition from confessional to ethnically conceived demands for equality, beginning in the 1790s and extending into the Vormarz; and (4) the attainment of ethnically individuated and politically expressed nationalism, which began with the 1848 revolts and was slowly completed in the latter part of the nineteenth century. The author deals mainly with the first two of these phases in Konfession und Nation. Turczynski's book is of substantial value in countering the prevalent, centuryold tendency to place primordial importance upon extraneous factors in explaining East European and Balkan nationalism. It makes a worthwhile contribution to understanding this phenomenon through a comparative approach to the internal dynamics of similar groups. The work suffers, however, from a lack of rigor in both form and content. This is manifested in uneven shifts of focus (ethnic, topical, and chronological), in repeated oscillation between depressingly vague terminology and concrete but parochial data, and in a strong tendency to substitute exposition for analysis. Especially in the later sections, it becomes apparent that the author's theoretical explications are insufficiently supported by the data adduced. This remains true despite an admirable bibliography and occasional archival references. The net effect is that he sheds a good deal more light on the continuing puzzle of the specifics of East European nation-building, without by any means exhausting the topic's possibilities for future research.


Avicennia alba is a plant that dominated in Peniti Mangrove Forest Pontianak regency. So many found leaf litter the region. Microorganism like celulotic bacterial has important role to degrade selulose in the litter. The aim of this study is to know genus selulose degrading bacterial in litter leaf of A. alba at Peniti Mangrove Forest. Sampel of litter leaf has taken by Composite Sampling Methode with 10 spot in 3 different location. Bacterial isolating by Pour Plate Methode with CMC selectif medium and the using sea water (environmental litter) for manufacturing suspension. The isolate bacterial was describe use coloni morphology test, cell morphology, and biochemistry. The result of isolation was found 14 pure isolation and after the identification was found 8 genera they are Pseudomonas , Plesiomonas , Pasteurella , Neisseria , Actinobacillus , Corynebacterium , Aeromonas , Vibrio


Extreme ultraviolet lithography (EUVL) is the most effective way to print sub-32 nm features. We have assessed EUVL resist readiness for 32 nm half-pitch (HP) manufacturing, presenting process feasibility data such as resolution, depth of focus (DOF), line edge roughness/line width roughness (LER/LWR), mask error enhancement factor (MEEF), resist collapse, critical dimension (CD) uniformity, post-exposure delay (PED) stability, and post-exposure bake (PEB) sensitivity. Using the alpha demo tool (ADT), a full field ASML EUV scanner, we demonstrate the feasibility of a k1 ~0.593 resist process for 32 nm HP line/space (L/S) patterning. Exposure latitude (EL) was 13% at best focus, and DOF was 160 nm at best dose using a 60 nm thick resist. By incorporating a spin-on underlayer, the process margin could be improved to 18.5% EL and 200 nm DOF. We also demonstrate ADT extendibility using a state-of-the-art EUV platform. A k1 ~0.556 resist process was demonstrated for 30 nm HP L/S patterns, providing a 13% EL, 160 nm DOF, and a common process window with isolated lines. 28 nm HP patterning for a k1 ~0.528 resist process could be feasible using a more advanced resist with improved DOF and resist collapse margin.


The phase formation, densification behavior, and microstructure development of Sr2NaNb5O15 (SNN) ceramics in both 10 wt% acicular Sr2KNb5O15 (SKN) seed-containing and unseeded systems were investigated in this work. SNN ceramics were reactively sintered from SrNb2O6 and NaNbO3 powders. The results show that the acicular SKN seeds not only accelerate SNN phase formation but also promote the densification at lower temperature. In reactive sintering, the acicular SKN seeds prepared by the molten salt synthesis method can give rise to the formation of a liquid phase and provide the structural framework for the grain growth of ceramics, leading to the formation of large anisotropic grains (>80 μm) in ceramics sintered at 1340°C. However, there are no such large anisotropic grains obtained in the SKN-free system. Observation of the large anisotropic grain growth is explained by the liquid-phase-assisted growth mechanism. For comparison, the microstructure evolution in the system with 10 wt% SKN seed, which was prepared by the conventional mixed-oxide method and without acicular morphology, was also investigated to further support the new growth mechanism.


Effect of heat treatment on microstructure and mechanical properties of 51CrV4 spring steel with different diameters for high-speed trains was investigated.The results show that tempered at 450~500 ℃,the microstructure of the tested steel consists of tempered martensite.With increasing tempering temperature,both the hardness and strength of the tested steel decrease,while the tensile and impact toughness slightly increase.The fractograph observation shows that the crack propagation path becomes more tortuous with the increase of tempering temperature,which indicats that the toughness is gradually improved.Under the tested heat treatment conditions,mechanical properties of the 51CrV4 spring steel with different diameters can satisfy the requirement of EN 13298 standard.


We evaluated the effectiveness of intraoperative wireless ultrasonography in determining the location of uterine incision during cesarean delivery in patients with placenta previa who have sonographic adherence findings in order to assess intraoperative blood loss and maternal morbidity.


Lawrence H. Schwartz , MD David M. Panicek , MD Alexandra R. Berk , MA Yuelin Li , PhD Hedvig Hricak , MD , PhD , Dr(hc) Purpose: To compare the content, clarity, and clinical usefulness of conventional (ie, free-form) and structured radiology reports of body computed tomographic (CT) scans, as evaluated by referring physicians, attending radiologists, and radiology fellows at a tertiary care cancer center.


Taking the squeezing silt project by blasting as an example,the pressure of shock in wave at measuring line and protected objects in wave is monitored in the operation.The propagation attenuation rule of blasting toe-shooting are analyzed,reaching an empirical calculation formula of shock in wave.As a result,the paper puts forward the safety control criterion of shock pressure in water for protected objects.The result not only ensured the safety of the construction and that of the surrounding buildings,but also complements the theory of squeezing silt by blasting and guides similarity engineering.