EpsteinBarr virus (EBV) and Cytomegalovirus (CMV) are ubiquitous in the human population causing a wide spectrum of diseases. Saliva can contain high counts of herpesvirus and is a common vehicle of horizontal transmission among close individuals. The objective of the present work was to determine the frequency of EBV and CMV DNA detection in saliva of HIV infected and non-HIV individuals and their relatives, assessing the role of HIV related immunodeficiency in salivary transmission. The study group comprised 240 individuals. Group 1: 40 HIV-infected patients; group 2: 40 non-HIV individuals; group 3: 2 non-sexual partners relatives for each patient from group 1 (n=80); group 4: 2 non-sexual partners relatives for each individual from group 2 (n=80). Each participant had non-stimulated whole saliva collected and DNA was extracted using Geneclean® kit II (BIO 101, La Jolla, CA, USA). EBV and CMV-DNA amplification were performed using a nested PCR protocol. EBV and CMV-DNA were detected in 7/40 (17.5%) and 5/40 (12.5%) individuals from group 1; 8/40 (20%) and 3/40 (7.5%) from group 2; 11/80 (13.8%) and 2/80 (2.5%) from group 3 and 8/80 (10%) and 1/80 (1.3%) from group 4, respectively. Among the 7 HIV/EBV co-infected individuals, 5 (71.4%) had a relative also infected with EBV (OR= 11.25, CI [1.7572.5], p= 0.011). Regarding group 2, among the 8 non-HIV and EBV infected individuals, 3 (37.5%) had a relative also positive to EBV (p= 0.320). Among the 5 HIV/CMV co-infected individuals of group 1, none had a relative CMV infected (p= 1.00). Regarding group 2, among the 3 nonHIV and CMV infected individuals, 1 (33.3%) had a relative also positive to CMV (p= 0.075). Based upon the results of the present study EBV and CMV-DNA is frequently amplified in saliva. HIV infected individuals and healthy controls showed a similar frequency of viral DNA detection. Relatives of HIV/EBV co-infected individuals are at greater risk of acquiring EBV through non-sexual contact.


Histogram equalization(HE) and adaptive histogram equalization(AHE) methods are introduced.On the base of them,weighted adaptive histogram equalization(WAHE) method based on power function is presented,and the generating mode of weight matrix and the algorithmic method of histogram distribution for the sliding window is given.Finally,the processing result of a digital X-ray image is given,and its effect is relatively satisfactory.


Low-power multipliers are very important for reducing energy consumption of digital processing systems. This paper discusses recent techniques proposed for low power array multipliers and presents their experimental comparison on 16x16 bit multiplier design.


The data published during recent 15-20 years on comparative, experimental and molecular embry- ology of unusually developing sea urchins have been reviewed. These animals are characterized by large lipid- rich eggs, highly modified embryogenesis, and the absence of a planktotrophic larva. Such a type of develop- ment is evolutionary advanced and arose independently in various phylogenetic lineages of the sea urchins.


Like libraries, corporations, government agencies, and not-for-profit organisations have to deal with documents in many different media and formats, but much of that information is unique and proprietary to the organisation. Some of an organisation's information assets may be held in relational databases or specialised applications, but much is unstructured text of the type information retrieval systems have been designed to deal with. The application of information retrieval technology to information finding within organisations has become known as " enterprise search ". Enterprise search may be interpreted [38] as search of digital textual materials owned by an organisation, including search of their external Website, company intranet, and any other electronic text that they hold such as email, database records and shared documents. Many characteristics of enterprise search represent a significant challenge for IR system designers [15, 57]. Information in the enterprise may be structured or unstructured. Documents are produced by a variety of sources, perhaps in many different languages, and generally without formatting standards. Metadata may be created according to a number of different schemes, or may not be added at all. Not all users have the same access rights to all information, and some information, such as employee records, are highly confidential. The need to federate across different repositories of information means that a single ranked list must be created for data from a variety of sources and formats. Different contexts may require different ranking methods. That is, search tools for the enterprise must perform many functions in addition to simple indexing and query processing. A basic search tool will not do. There is an expectation, based on experience with the Web, that finding corporate information should be fast and efficient, and that it should be done through a single interface. However within organisations these expectations have typically not been met, and there is evidence that employees spend a significant amount of their time searching for, and often failing to find, information needed to perform their work. For instance, • According to IDC, a company with 1,000 information workers can expect more than $5M in annual wasted salary costs because of poor search. They report that people spend 9-10 hours per week searching for information and aren't successful from one-third to half of the time [46]. • According to Butler Group, as much as 10% of a company's salary costs are wasted through ineffective search [26]. • A 2007 …


Phytochemical studies on barks of Artocarpus teysmanii Miq. (Moraceae) have resulted in the isolation of four compounds, xanthone-lactone derivative, artonol B 1, furanodihydrobenzoxanthone derivatives, cycloartobiloxanthone 2 and artobiloxanthone 3 and isoprenylated flavone, artonin E 4.


A two stage linear programming approach is used to estimate the willingness to pay (WTP) of individual households or groups of households for changes in a combination of probabilistic water supply reliability and retail price of water. By modeling the costs (financial and 'perceived') of implementing long and short-term conservation measures and assuming rational (expected value cost minimizing behavior), demand curves for water and expected water use curves can be estimated. Derived demand curves for conservation measures can also be calculated. Next Monte Carlo simulation techniques are used to represent household variability in the model parameters and derive estimates of aggregate WTP for water supply reliability, water demand curves and demand curves for conservation measures. Several examples are provided to illustrate the approach.


Many of the essential transformations needed to meet the Sustainable Development Goals (SDGs) will need to be met in local areas and by local actors. The Global Sustainable Development Report (GSDR) 2019i and the political declaration of the High-level political forum 2019. These transformations are mutually reinforcing and strongly linked to the Sustainable Development Goals (SDGs). The report identifies six entry points and four levers to accelerate progress across all 17 SDGs at the global level1 including Urban and Peri-Urban Development.


T cells induced by viral infection are maintained atunexpectedly high frequencies in the spleen. While it has been established that these memory cells arephenotypically heterogeneous, relatively little is known about the functional status of these cells. Here weinvestigated the proliferative potential of CD8


In this paper, based on the noise signal, BBD ball mill material detection method and mill pulverizing system optimization control are presented. The noise of ball mill is decomposed using wavelet packet. The eigenvectors reflecting coal level of mill can be obtained from wavelet packet parameters. Through neural network training, the statistical model of coal level and ball mill eigenvectors is established. Therefore, the accurate material measurement is implemented. In addition, according to detection results, the mill optimal control method is also studied, based on neural network internal model control. This method can solve the control problems of ball mill, such as nonlinear, close coupled variables. Finally, the experiment results demonstrate the good performance of proposed method.


To cite this article: Stephen A. Adefegha, Ganiyu Oboh, Bathlomew M. Okeke & Sunday I. Oyeleye (2017) Comparative Effects of Alkaloid Extracts from Aframomum melegueta (Alligator Pepper) and Aframomum danielli (Bastered Melegueta) on Enzymes Relevant to Erectile Dysfunction, Journal of Dietary Supplements, 14:5, 542-552, DOI: 10.1080/19390211.2016.1272661 To link to this article: https://doi.org/10.1080/19390211.2016.1272661


Closed‐form expressions for the physical optics (PO) field scattered in the far zone by perfectly electrically conducting (PEC) plane angular sectors with a conical‐section boundary are derived in terms of incomplete cylindrical functions (ICFs). The developed representations are very efficient from a computational point of view and constitute a useful tool to analytically predict the radar cross section (RCS) of metal plates with both convex and concave curved edges. The correctness of the proposed scattered field formulas is demonstrated through comparisons with the results obtained by an accurate completely numerical PO approach. A sample analysis of the scattering from a more elaborate geometry, which can be seen as a juxtaposition of angular sectors, is also presented. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 50: 160–165, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22989


In 1580, the archbishop of Milan, Cardinal Carlo Borromeo, and Spanish governor, Antonio de Guzmán y Zuñiga, Marquis de Ayamonte, appeared to be at an implacable standoff. Six years prior, Borromeo had excommunicated the previous governor, Luis de Requesens y Zúñiga, over the issue of Borromeo's personal police force. The new governor was faring little better, clashing with the cardinal about everything from religious ceremonies to urban development projects.1 For the second year in a row, the governor gave orders for the traditional Carnival performances in which he would also take part. Once again, Borromeo responded by publishing an act threatening excommunication for all participants, which Ayamonte proceeded to ignore soundly. It piqued the Ayamonte's anger when the newly-excommunicated flocked to the cardinal, seeking his absolution, including some of the governor's personal guests. On 1 March 1580, perhaps intending retribution, but certainly the final word, Ayamonte ordered the raid and closure of the cardinal's seminary print shop, jailing its printers.2 Historians have often approached the crisis of 1579/1580 from a biographical perspective, emphasising the conflict between the Spanish governor's adherence to courtly protocol and martial hierarchy, and Borromeo's own uncompromising devotion to recreating the Ambrosian church.3 The raid on the


OBJECTIVE: To assess the contribution of intrinsic tissue damage in cortical lesions (CLs) to cognitive impairment in patients with relapse-onset multiple sclerosis (MS), combining double inversion recovery (DIR) and diffusion tensor (DT)-MRI.
 BACKGROUND: The number and volume of CLs, identified using DIR sequences, correlate with the severity of clinical disability and cognitive impairment in MS patients.
 DESIGN/METHODS: Brain DIR, DT-MRI, dual-echo and 3DT1-weighted scans were acquired from 113 MS patients and 40 healthy controls (HC). Cognitively impaired (CI) patients had abnormalities in >2 neuropsychological tests of the Rao's battery. Diffusivity values in CLs, skeletonised cortical GM, white matter (WM) lesions and normal-appearing (NA) WM were assessed. Between-group comparisons were performed using the Mann-Whitney and the Pearson chi-square tests. A random forest (RF) analysis was performed to identify the predictors of cognitive impairment and to rank variables importance.
 RESULTS: Compared to HC, MS patients had a significantly lower fractional anisotropy (FA) and higher axial (AD), radial (RD) and mean diffusivity (MD) in the skeletonized cortical GM and NAWM. CLs had higher FA (p=0.01), MD (p=0.0006) and AD (p=0.04) vs HC skeletonized cortical GM, as well as higher FA (p=0.008) vs patients' skeletonized cortical GM. Thirty-five (31.0%) patients were found CI. Compared to cognitively preserved (CP) patients, CI patients had more severe damage, quantified using DT-MRI, in WM lesions, skeletonized cortical GM and NAWM (p values ranging from <0.0001 to 0.002). Intrinsic damage of CLs did not differ between the two groups. Age, disease duration, FA of the skeletonized cortical GM and MD of the NAWM best predicted cognitive impairment in MS patients (C-statistic=0.88).
 CONCLUSIONS: "Diffuse" damage to the GM and NAWM, rather than intrinsic damage to CLs, seems to play a prominent role in the cognitive impairment of MS patients, probably as a consequence of Wallerian and trans-synaptic degeneration.
 Study Supported by: a grant from Fondazione Italiana Sclerosi Multipla (FISM/2008/R/13) Disclosure: Dr. Morelli has nothing to disclose. Dr. Rocca has received personal compensation for activities with Biogen Idec and Serono Symposia International Foundation. Dr. Pagani has nothing to disclose. Dr. Preziosa has nothing to disclose. Dr. Copetti has nothing to disclose. Dr. Rodegher has nothing to disclose. Dr. Esposito has nothing to disclose. Dr. Falini has nothing to disclose. Dr. Comi has received personal compensation for activities with Sanofi-Aventis Pharmaceuticals Inc., Novartis, Merck Serono, Biogen Idec, Bayer Pharmaceuticals Corp., Teva Neuroscience, and Actellion. Dr. Filippi has received personal compensation for activities with Teva Neuroscience and Genmab AS as a member of scientific advisory boards, and Bayer Pharmaceuticals Corp. as a consultant. Dr. Filippi has received research support from Bayer Schering, Biogen Idec, Genmab AS, Merck Serono, Teva Neuroscience, the Italian Ministry of Health, and the Fondazione Italiana Sclerosi Mult.


The love-storm is a very frequent topic in the classical literature. In this study I present some icons of lovestorm in contemporary Spanish literature.


Hypoxia‐inducible factor‐1α (HIF‐1α) has been reported to be up‐regulated in psoriatic epidermis, resulting in increased proliferation and abnormal differentiation of human keratinocytes (KCs). However, the role of HIF‐1α in psoriatic epidermis, which is mainly composed of KCs, is poorly understood. Here, we show that morphogenic protein 6 (BMP6) is down‐regulated when HIF‐1α is upregulated in patients with psoriasis skin lesions. HIF‐1α overexpression in primary human KCs promoted proliferation and inhibited terminal differentiation. Furthermore, HIF1‐α repressed the expression of BMP6 by binding directly to the hypoxia‐response element (HRE) in the BMP6 promotor region, which shows that BMP6 is a novel target gene of HIF‐1α. We also found that HIF‐1α‐mediated BMP6 suppression could alter the proliferation status by modulating the expression levels of cell cycle regulatory proteins and also affect the early differentiation of KCs. Therefore, we suggest that HIF‐1α‐dependent BMP6 suppression has a critical role in the induction of hyper‐proliferation and abnormal differentiation in psoriatic KCs.


ABSTRACT Ken Mathers, long-time roads bureaucrat in the Victoria Public Service, has been a uniquely influential figure on the state's transport scene since the late 1990s. His projects have dominated the agenda, sometimes against the initial misgivings of the governments he served. This article argues we can explain Mathers' influence in terms of policy entrepreneurship. It will show that, contrary to the dominant view in recent scholarship, transport policymaking in Victoria is sufficiently messy that an entrepreneur like Mathers could shift the agenda to get his projects up, looking in particular detail at the case of the now-infamous East-West Link. Finally, examining the failure of East–West, it will suggest some doubts about whether we can really expect entrepreneurs to wrangle all the relevant political actors, and whether they are in fact as central to policy change as the theory leads us to think.


This study proposes a novel image inpainting technique based on watermarking and halftoning. This technique use LSB method to embed error diffusion halftone image into original image for protecting the image. In image repair process, we use LSB method to extract the halftone information, and the reference image is achieved from LUT inverse halftone. Finally we use the reference image to finish the image inpainting work. Experiment shows the performance of our method is very excellent in image inpainting.


Unconformity‐related uranium (URU) deposits in the Athabasca Basin, Canada, include the highest grade, large tonnage deposits in the world. Recent studies of the Patterson Lake corridor uranium deposits suggest a deep heat source enhances hydrothermal fluid flow and incursion of basinal brines along brittlely reactivated ductile shear zones. However, the spatial extent of the ore systems and lower crustal features capable of driving the hydrothermal cells remained largely unresolved. Three‐dimensional electrical conductivity models derived from inversion of magnetotelluric data and coincident gravity modeling identified a voluminous conductivity anomaly and corresponding gravity low related to a belt of high‐heat producing intrusions that dips below the deposit. Shallow conductive bodies are identified below the deposits and similarly prospective corridors. The volume and location of the intrusive bodies may have provided a source of radiogenic heat that helped drive remobilization of fluids along reactivated structures, redefining the spatial extent of URU systems.


| Collaboration between ASME and API extends Fitness-For-Service principles to industries beyond refining. By David A. Osage and Umberto D'Urso.


The effects of coiling temperature on the microstructure and nano-scaled precipitates of ultra-low carbon steel with deep drawability,together with the corresponding textures of the annealed cold-rolled sheet,were investigated by Gleeble-1500 hot simulator,X-ray diffraction,optical microscopy and transmission electron microscope.It is found that nano-scaled precipitates in the hot-rolled steel sheet are mainly CuS and CuS-MnS.The precipitates are less,coarse,and sparse when the coiling temperature is lower.To obtain a strong favorable texture and a better drawing property,the best coiling temperature should be under 600 ℃.


Many tropical and subtropical fruits and vegetables, such as citrus, are sensitive to low chilling temperatures and, thus, must be stored after harvest at relatively high temperatures that enhance their deterioration. In previous studies, we found that a short pre-storage hot water rinsing treatment (at 62°C for 20 s) markedly increased chilling tolerance in grapefruit and reduced the development of chilling injuries following 6 weeks of cold storage at 2°C. Molecular analysis studies using PCR cDNA differential display and PCR cDNA subtraction techniques revealed that the hot water treatment increased the expression of several stress-related cDNAs in the fruit peel tissue, including heat shock proteins (HSPs), dehydrins, and a sodium proton antiport gene known to be involved in plant salt tolerance. Evaluation of gene expression patterns showed that many of these stress genes were only temporarily induced by the heat treatment alone when the fruit were kept at ambient temperatures, but markedly and continually expressed by the combination of heat followed by cold storage.


Excerpt To the editor: In the February issue of the ANNALS OFINTERNALMEDICINEwe reviewed data bearing on the hypothesis that individuals with reduced or absent gastric acid secretion are unduly sus...


ABSTRACT
 The fruit fly Bactrocera tryoni (Froggatt) (Diptera: Tephritidae) is a species of significant quarantine concern to many countries. Currently, B. tryoni is found in parts of Australia and on some Pacific islands. Understanding dispersal behavior is important for the development of scientifically justified trade restrictions or quarantine distances for B. tryoni. These distances ensure adequate protection for overseas markets while also ensuring that growers sufficiently distant from the affected area are able to retain unrestricted access to markets. This review considers scientific data on dispersal and uses this information to make recommendations for appropriate quarantine distances. Most studies conclude that the lifetime dispersal distance of this species rarely exceeds 1 km, although three studies indicate that longer dispersal distances of a small number of individuals may occasionally occur. These short dispersal distances are consistent with findings for other fruit fly species. Triggers for long-distance dispersal, the fate of these individual flies, nutritional requirements to support this dispersal, and reasons for discrepancies in the dispersal distances reported in different studies are reviewed. Reasons for the inability of B. tryoni to establish along southern parts of the east coast of Australia before European colonization are postulated. A proposed quarantine distance is based on the scientific basis of the mean and 3 SD, with a 3-fold level of protection based on distance. It is proposed that an area contained by a circle with a radius of 1.2 km is a reasonable quarantine area for B. tryoni outbreaks where flies are contained within 200 m of an epicenter. Where total trappings are contained within 400 m of the epicenter, a quarantine distance of 2.4 km is recommended. Three other quarantine distances are proposed based on the formula by using the mean.


We propose a two-market heterogeneous agents model with coupling mechanism to study Financial crisis with contagion effect. It manages to calibrate sudden crash behavior of US and UK stock markets during "Black Monday" of 1987 besides smooth crisis and disturbing crisis categorized in literature. It is implied that financial crisis and its contagion could be endogenous and supports scenario of over-valuation causing financial crisis. In addition, the model shows that financial system could be fragile in which small shock(s) hitting individual market's fundamental could cause financial crisis which spreads to other market. It also supports scenario of external shock triggering financial crisis. Lastly, the model manages to match typical stylized facts, especially cross-correlation which is exclusive to multi-market case.


PRODUCT IDENTIFICATION CAS NO. 110-44-1 EINECS NO. 203-768-7 FORMULA CH3CH=CHCH=CHCOOH MOL WT. 112.13 H.S. CODE 2916.19.2000 TOXICITY Oral, rat LD50: 7360 mg/kg SYNONYMS (E,E)-2,4-Hexadienoic acid; 2-Propenylacrylic acid; alpha-trans-gamma-trans-Sorbic acid; trans,trans-Sorbic acid; Preservastat; Sorbistat; Hexadienoic acid; 1,3-Pentadiene-1-carboxylic acid; Panosorb; (2-Butenylidene)acetic acid; Crotylidene acetic acid; Acide sorbique; Kyselina 1,3-Pentadien-1-karboxylova; Kyselina sorbova; Hexa-2,4-dienoic acid; Other RN: 91751-55-2 SMILES C(=C\C=C\C)\C(O)=O CLASSIFICATION Antimicrobial agent, Preservative, Fungicide, Bactericide EXTRA NOTES Mold and yeast inhibitor. Used as a fungistatic agent for foods EPA Pesticide Chemical Code 075901 E number 200 PHYSICAL AND CHEMICAL PROPERTIES PHYSICAL STATE White crystalline powder MELTING POINT 134.5 C BOILING POINT 228 C (Decomposes) SPECIFIC GRAVITY 1.204 SOLUBILITY IN WATER Slightly pH VAPOR DENSITY 3.87 log P 1.33 (octanol-water) AUTOIGNITION NFPA RATINGS Health: 0 Flammability: 1 Reactivity: 1 REFRACTIVE INDEX FLASH POINT 126 C STABILITY Stable under ordinary conditions EXTERNAL LINKS & GENERAL DESCRIPTION


European Nickel (EN) constructed a heap leach demonstration plant (3 heaps and precipitation plant) to prove both technically and economically the success of leachability for Caldag Nickel laterites using atmospheric heap leaching (AHL) by sulphuric acid and to produce saleable products. Heap 1 (average Caldag ore) underwent leaching for 548 days extractions were 79.4%Ni, 82.7%Co, 30.0%Fe, 78.9%Mn and 37.1%Al. The heap is in its final rinse stage. The precipitation plant produces 2 nickel products, primary (24-35%Ni) and secondary (15-30%Ni & 2.5%-11%Mn). Products have been sold to various refineries for evaluation. This paper presents the first heap AHL performance.


To lay the foundation of strategy development for improving the nurse image of the future by grasping the nurse image and to provide the basic data for promoting the application of excellent students to nursing by grasping the awareness which can affect their careers, this study was conducted for the high school students who were in the stage of a career choice. This study was conducted from June 20, 2014 to July 31, 2014 and the data from the 320 male and female students of 4 high schools in M and S regions was used for analysis. The collected data was analyzed by frequency, percentage, t-test, ANOVA, and Pearson's correlation coefficients according to the study purpose with SPSS Window 21.0 Program. The results of the study are as follows: First, in a correlation between nurse image perceived by high school students and the characteristics of a career choice, it was indicated that the nurse image perceived by high school students had a correlation with the subjects to consult with for a career choice (r = –.124, p = .027), whether they have intention to consider nursing (r = –.133, p = .017), why they consider nursing (r = –.122, p = .029), and why they don't consider nursing (r = 114, p = .041).Second, in the correlation of image and the characteristics of a career, the occupational image had a correlation with business image (r = .642, p = .000), the social image did with business image (r = .530, p = .000) and the occupational image (r = .671, p = .000), and the individual image did with business image (r = .831, p = .000), the occupational image (r = .609, p = .000), and the social image (r = .581, p = .000). The subjects to consult with for a career choice did with business image (r = –.132, p = .018) and individual image (r = –.137, p = .014), whether they have intention to consider nursing did with the occupational image (r = –.205, p = .000) and the social image (r = -.237, p = .000), why they consider nursing did with the occupational image (r = –.195, p = .000), the social image (r = –.221, p = .000) and whether they have intention to consider nursing (r = .969, p = .000), and why they don't consider nursing did with the occupational image (r = .143, p = .010), the social image (r = .144, p = .010) and whether they have intention to consider nursing (r = –.666, p = .000).


Isolated regions and islands are facing imported fossil-fuel dependency, higher electricity prices, and vulnerability to climate change. At the same time, they are increasing their renewable penetration and, therefore, risk for electric utilities. Integrating stochastic energy resources in noninterconnected systems may take advantage of an intelligent and optimized risk-averse unit commitment (UC) model. This paper presents a two-stage stochastic UC model with high renewable penetration including reserve requirements for the efficient management of uncertainty. In order to account for the uncertainty around the true outcomes of load, wind, and photovoltaic (PV) generation, a minimum conditional value at risk term has been included in the model formulation. A stochastic measure of the value of the stochastic solution is used to evaluate the benefits of using stochastic programming. The model considers the need for reserves dependent on the forecasting horizon and the amount of renewable generation. Active power demand, and wind and PV generations are considered as probability distribution functions. The model is applied to the Lanzarote-Fuerteventura system in the Canary Islands, Spain, and Crete, Greece.


In this paper, we first investigate the classification of positively homogeneous equations $(\phi_p(u'))'+q(t)\phi_p(u)=0$, $u(0)=0=u(1)$, where $p>1$ is fixed, $\phi_p(u)=|u|^{p-2}u$ and $q\in L^{\infty}(0,1)$, and then discuss the existence of solutions for non-homogeneous equations. The main method of classification is by using a generalized Prufer equation $$ \theta'=|\4\cos_p\theta|^p+\frac{q(t)}{p-1}|\4\sin_p\theta|^p\quad\text{for }t\in(0,1), $$ where $\sin_p:\mathbb{R}\to[-1,1]$ is a periodic function and $\cos_pt=\mathrm{d}\sin_pt/\mathrm{d} t$ for $t\in\mathbb{R}$.


Molded body manufacturing apparatus according to the present invention, prior to filling the molding material into the cavity, through the release agent application means, in a state above the upper surface of the opening located in the cavity in the punch upwardly ejecting punch surface release agent, so that the removal agent is coated on the lower mold punch surface and the lower surface of the punch is located below the upper end face of the opening of the cavity within the cavity of the injection mold release agent punch surface down state, so that the mold releasing agent is applied to the lower punch surface the upper and lower punch faces of the exposed inner peripheral surface of the cavity. Accordingly, the molding material can be prevented from sticking to the surface of the upper punch, lower punch and an inner circumferential surface of the cavity surface.


Academic circles published about 100 essays and 20 books on Zhu De from 1998 to 2005.The(research) publications mainly refer to Zhu De's theories on socialist comstruction with Chinese characteristics,ideological construction,the ruling Party's construction,military thought and the leading group of the first generation.In the coming years,we must strengthen the research of Zhu De in the following five aspects:editing and publishing Zhu De's works,publishing the index of research books throughout the country about Zhu De,evaluation Zhu De objectively and scientifically,publishing Zhu De's documents more for the journals like "The Party's Documents",and revising "The Chronological Life of Zhu De".


Dear Editor, Multiple eruptive keratoacanthoma is a rare adverse event (AE) of nivolumab. A 73-year-old Japanese man visited our outpatient clinic with a 1-month history of multiple asymptomatic hyperkeratotic nodules on the upper arm. He had been treated for cervical squamous cell carcinoma (SCC) with nivolumab (3 mg/kg b.i.d) for 2 months. One month before the initial visit, he developed a grade 3 fever and skin eruption, and was administrated methylprednisolone 2 mg/kg. At his initial visit, physical examination revealed multiple infiltrated hyperkeratotic plaques and nodules surrounded by erythematous macules on the dorsal hand


This article studies the phenomenones from the alienation of science and technology, pointing out that alienation is not science and technology itself but the misuse and abuse of it. To research the original reasons, we must see from the angle of the limitation of human congnition, value idea and social developing condition. We must construct a interact mechanism between science and technology and society.


The invention discloses a preparation method of pemetrexed disodium, which comprises the following steps: preparing 4-(4,4-dialkoxy-1-butenyl)benzoate 6 and 4-(3-formyl-3-halo-1-propenyl)benzoate 7, carrying out ring-closing reaction on the compound 7 and 2,4-diamido-6-hydroxypyrimidine under the action of an alkali to obtain a compound 9; carrying saponification on the compound 9, and acidifying to obtain a compound 10; carrying out condensation reaction on the compound 10 and diethyl L-glutamate to obtain a compound 11; carrying out catalytic hydrogenation reaction on the compound 11 under the action of a catalyst to obtain a compound 12; and carrying out hydrolysis reaction on the compound 12 under the action of an alkali to obtain the target product pemetrexed disodium 1. The method has the advantages of accessible raw materials, wide sources, low preparation cost and low price, is suitable for industrial production, and solves the problems of high preparation cost and difficulty for industrial production in the prior art.


INTRODUCTION: The burden of coronary artery disease (CAD) continues to rise globally, as well as in India, recognizing sub clinical atherosclerosis is of paramount importance for prevention of CAD, stroke, and peripheral vascular disease. The early phase can be studied by two dimensional B-mode ultrasonography. This technique yields information on atherosclerotic wall changes that cannot be obtained by conventional angiography. Its non-invasive character and easy applicability make B-mode ultrasonography a powerful tool for measurement of the atherosclerotic burden. Carotid intima-media thickness (IMT) is defined as the intimal plus medial thickness as the distance between the leading edge of first echogenic line to the leading edge of second echogenic line on far wall of common carotid artery. AIM: To determine the association between carotid intima- media thickness and coronary artery disease. METHODOLOGY: A total of 180 individuals (90 patients with coronary artery disease and 90 controls coming to the department of Cardiology, were studied. All individuals were subjected to clinical examination and investigations and relevant data was collected. Ultrasound scanning of the carotid arteries was performed as per ASE (American society of echocardiography) guidelines and common carotid intima-media thickness was measured. P value less than 0.05 was considered significant. RESULTS & CONCLUSIONS: Mean common carotid IMT in patients with established coronary artery disease was 0.86±0.17 mm and in persons without significant clinical coronary artery disease it was found to be 0.58±0.08 mm. Common carotid IMT was found to be higher in diabetes, hypertension, and those with high triglycerides and low HDL. There is no correlation between common carotid IMT with history of smoking total cholesterol or LDL cholesterol levels. Cut off value of 0.8m.m of common carotid intima-media thickness has a sensitivity of 58.3%, specificity of 97.77% and positive predictive value of 63.76% in differentiation of persons with significant coronary artery disease from their counterparts.


To understand how the activity budgets of ectotherms vary in mountain areas with high microclimatic and habitat heterogeneity, and how these factors together with habitat modulate the assemblage of ectotherm communities.


Experiments are described in which field‐reversing E layers were transported axially in RECE‐Christa over a distance of up to 10 ring radii using time‐varying magnetic fields. When properly executed, this process does not lead to anomalous fast‐electron losses. The translation speed appears consistent with that expected from the interaction of the rings with the axial Bz‐field gradients and the resistive tank wall. No significant difference is observed between moving the rings in a homogeneous H2 fill and moving them from a transient gas cloud into a low‐gas‐density region.


Abstract The 'new middle class', often identified as an upwardly mobile segment, primarily employed in the growing private service sectors, such as the information technology, and supposedly, representative of the changing lifestyles and consumption patterns of the Indian middle class, has stolen much of the limelight of the contemporary popular as well as scholarly discourses on the Indian middle class. 2 2   This article draws upon from the fieldwork conducted as part of my PhD work completed in 2016. An earlier version of the paper was presented at the international seminar on 'The Middle Class in World Society' held at ISEC (Institute of Social and Economic Change), Bangalore, India on 16th and 17th December, 2016. This article, on the other hand, takes up a different social group located in West Bengal, having a close relationship with the state, often described as the 'old middle class'/'Nehruvian middle class' in the postcolonial context, the respondents being predominantly public sector employees and academicians. By taking up the register of sanskriti (culture), the article argues that it is fundamentally through forging continuity from the past that this historically dominant social group is engaged in the construction of Bengali middle classness. Through an analysis of class and its relation to cultural distinctiveness, the article shows that the specific way in which this relation plays out in case of the respondents in my study and argues that any theoretical attempt to understand the complex relationship between class distinction and the question of taste needs to be grounded within narrowly defined contextualised specificities.


AbstractThe Cherepovets country has historically benefited from a favorable transport geography on the divide between major drainage basins. While the White Sea trade through Arkhangel'sk flourished, the region was situated at the intersection of south-north routes between Moscow and the White Sea and west-east routes between Novgorod and Vologda. After the rise of St. Petersburg, the economic-geographic situation of the region was reoriented toward the Baltic Sea. Industrial development in the region was fostered by the construction of the Tikhvin, Mariinsk and North Dvina waterways in the early 19th century. Metalworks and flour mills, based largely on long-haul raw materials, flourished in the first half of the 19th century. These industries declined when the construction of railroads deprived the region of its favorable transport situation on waterways, and lumbering, sawmills and paper and board production became the principal economic activities. Other industries that developed in the second half of...


We discuss the existence, uniqueness and stability exponential and polynomial of global solutions for a nonlinear coupled system with nonlocal boundary conditions given by utt + ∆ u + f(u− v) = 0 in Ω× (0,∞), vtt −∆v − f(u− v) = 0 in Ω× (0,∞), u = 0 on Γ0 × (0,∞), −u + ∫ t 0 g1(t− s)B2u(s)ds = 0 on Γ1 × (0,∞), ∂u ∂ν = 0, on Γ0 × (0,∞), ∂u ∂ν + ∫ t 0 g2(t− s)B1u(s)ds = 0 on Γ1 × (0,∞), v = 0 on Γ0 × (0,∞), v + ∫ t 0 g3(t− s) ∂v ∂ν (s)ds = 0 on Γ1 × (0,∞), (u(0, x), v(0, x) = (u0(x), v0(x)), (ut(0, x), vt(0, x)) = (u1(x), v1(x)) in Ω where Ω is a bounded region in <2 whose boundary is partitioned into disjoint sets Γ0, Γ1. We show that such dissipation is strong enough to produce uniform rate of decay. Besides, the coupled is nonlinear which brings up some additional difficulties, which makes the problem interesting.


Nowadays, using E-Health technologies has enabled health services to reach patients worldwide efficiently anytime anywhere. Internet of things (IoT) revolution bringing booming in healthcare sector. E-Health caring has created a dazzling and cheap checking organism for obtaining greater comfortable living to the people torment from a variety of diseases utilizing diverse techniques like wireless exchanges, wearable and convenient remote health monitoring tools. This paper provide a recent reviewing of E-heath caring platform and present a tabulate form of many systems according to the IoT layers, with the main advantages and disadvantages. To guide the researchers on the most important future works in each layer.


Context: Immobile over-retained primary teeth often deflect the path of eruption of their corresponding permanent teeth, resulting in ectopic eruption. Although various etiologies have been mentioned in literature, there is little regarding its association with consistency of diet and the presence of crowding. Aim: This study was undertaken to evaluate the association between the presence of immobile over-retained primary incisors (IOPIs), the consistency of foods consumed, and the presence of crowding. Materials and Methods: A total of 101 children with IOPI were randomly selected for evaluation. The consistency (soft, medium, or hard) of the foods consumed by each child during the day was assessed. The presence of crowding in the arches, the number of IOPI present, and the length of the root of each IOPI following its extraction were also assessed. Statistical Analysis: It was carried out using the SPSS software (version 11.5, IBM Corporation, Armonk, New York, USA). The Chi-square test and the Z test were used. Results and Conclusion: No significant association was found between IOPI, the consistency of foods consumed, and the presence of crowding.


The esterifying effects of monascus,daqu and rhizopus strain on single acid(acetic acid,caproic acid,lactic acid,butyric acid) and mixed acid(acetic acid,caproic acid,lactic acid,and butyric acid mixed together according to the ratio of 1∶1∶1∶1) were studied.The results suggested that monascus could advance the esterification of caproic acid,butyric acid,mixed acid and ethanol with the produced esters as ethyl caproate which had extremely strong esterifying power,Daqu could advance the esterification of caproic acid,butyric acid,mixed acid and ethanol with the produced esters as ethyl caproate,besides,it could advance the esterification of acetic acid and ethanol to produce ethyl acetate,and rhizopus could advance the esterification of caproic acid,mixed acid and ethanol by producing small amount of ethyl caproate and ethyl lactate.


Evolutionary algorithms (EAs), in general, and genetic algorithms (GAs), in particular, are popular and efficient search metaheuristics, which have been applied for many complex optimization problems. At the same time, the performance of EAs depends on appropriate choice of the EA's structure and parameters. One of the ways to automate the EA design is to apply a hyper-heuristic approach. The hyper-heuristic is a high-level approach that can select and apply an appropriate low-level heuristic at each decision point. In this paper, we present a selection hyper-heuristic with online learning that is used to design and adaptively control an ensemble of many different genetic algorithms. The proposed approach combines concepts of the island model and cooperative and competitive coevolutions. The general method and some particular applications are discussed. The experimental results for a wide range of optimization problems are presented. The experiments show that the proposed approach outperforms its component metaheuristics on average. It also outperforms some state-of-the-art techniques. The main advantage of the approach is that it does not require the participation of the human-expert, because it operates in an automated, self-configuring way.


For the past fifteen years, regional conservation planning has been at the forefront of land use decisions in Pima County, Arizona. In 1998, Pima County adopted the groundbreaking Sonoran Desert Conservation Plan; part of this process involved identifying "Critical Landscape Connections," or wildlife linkages, that were particularly threatened by barriers such as highways and development. Then, in 2006, Pima County voters approved the Regional Transportation Authority (RTA) Plan, which is funded by a 20-year ½-cent sales tax and includes $45 million of dedicated monies for wildlife linkage projects. Since 2006, the RTA Wildlife Linkages Working Group, comprised of members representing all the local jurisdictions and two non-governmental organizations, has begun distributing this $45 million to an array of research projects, planning efforts, and the construction of wildlife crossings along major regional roadways. Research projects have included an investigation of appropriate fencing methods specific to wildlife in the Sonoran Desert and roadkill surveys conducted as a precursor to the siting of wildlife crossings. The Arizona Game and Fish Department also completed a detailed assessment of Pima County's wildlife linkages in 2012. This document and associated maps will help local land-use planners identify specific wildlife linkage challenges and opportunities on local transportation projects. Thus far, the bulk of the money allocated has been to the construction of wildlife crossings along local roads and highways. These projects reflect a variety of scales, from the addition of small pipe culverts to the first wildlife overpass ever built in the Sonoran Desert. $11 million was allocated for one underpass and one overpass and associated fencing along State Route 77, the largest project funded to date. These crossings will be built by the Arizona Department of Transportation, starting in late 2013, as part of their larger project to widen a section of State Route 77 from four to six lanes. Two underpasses are currently under construction along State Route 86 on the Tohono O'odham Nation, with plans for an additional wildlife overpass approved for the future. A series of wildlife underpasses were approved for two local roadways, Tangerine Road and Silverbell Road, and will be phased into these projects when the roads are widened in coming years. Other smaller projects have rounded out the portfolio of innovative projects funded by the Working Group. Due to the adoption of the Sonoran Desert Conservation Plan and the creation of the RTA, regional and widespread support now exists for projects that address the re-connection of Sonoran Desert wildlife linkages in transportation projects. Along the way, many challenges have been overcome with local landowners and agencies. Local non-profit organizations have been essential in executing both community outreach efforts and behind-the-scenes negotiations and bridge-building that has proven crucial to the success of these projects. Despite many challenges, local planners, transportation engineers, conservationists, and the larger community are moving forward with the first plan – and an assured local funding mechanism – that addresses wildlife linkage conservation on a regional scale in the Sonoran Desert.


This paper describes and compares the psychology curricula in four Western European countries. Ireland and the UK are similar to each other, both being based on three year undergraduate programmes followed by quite separate professional training. There is considerable similarity in the areas covered in the curriculum. Belgium and Holland have integrated training programmes lasting four or five years. The first one or two years of these involve a general introduction to psychology which covers much the same areas as those included in undergraduate programmes in the UK and Ireland.


The present invention has been to provide a cover production method and apparatus including a multiple metal layer comprising the steps of semi-finished cover which is provided with a second metal in a liquid form different metal to the first metal layer with a mold form to form a first metal layer (a the semi-finished cover), and the step (injecting) for injection to form a second metal layer on the first metal layer, and a step (pressing) of the pressing pressure with the second metal in the mold. The multilayer is manufactured by the above method the metal cover, as well as having the strength and elasticity of the composite metal, such as heat treatment, anodizing, galvanic plate, vacuum coating / film treatment, coating treatment, painting treatment and anticorrosion treatment required as the metal cover subjected to surface treatment to improve adhesion, stiffness and sikryeok between the metal layer and create a more flexible cover design.


Current e-learning environment do not adequately support collaboration among students and between students and lecturers. This paper presents the design principles, prototype design and heuristic evaluation of teach, learn and research (TELEREC) e-collaboration environment for higher educational institutions. The objectives are to investigate existing design principles and didactics for e-collaboration to ascertain a realistic option for designing and developing an e-collaboration environments; second, to report on the implementation of the prototype design using a blended learning approach; and finally, to conduct formative assessment and experts' evaluation of the system. The methodological approach followed a design research approach which also integrates the values and practices of iterative development as well as user-centered design activities. The results of the study suggest that TELEREC e-collaboration environment support important usability elements such as navigability, consistency, efficiency, attractiveness, visibility and controllability as discussed in the findings.


Three dimensional computer graphics are common nowadays for games and are beginning to be used in other applications as well, such as for displaying information, navigation on the internet and as an interface to programs. As always, though, a new computer interface form such as this excludes a number of potential users. In this case, those people who are not able to see the graphics and others who are physically unable to manage the input devices necessary to control a viewpoint and objects in three dimensional movement.


The development of technology has rapidly evolved and has covered a lot of sectors, including financial sectors, which can be seen by the evolution in payment methods such as e-payment. As people's needs keeps on developing, the technology that is available now might not be relevant to fulfil people's needs in the future. This study aims to explore the factors influencing people's intention to adopt electronic payment by examining the correlations of the electronic payment adoption with Perceived Ease of Use, Perceived Usefulness, Perceived Risk, Perceived Trust, Compatibility, and Perceived Cost. Extended Technology Acceptance Model (TAM) by Davis (1985) is used for this study to develop the variables. The data was obtained by distributing online questionnaires using Likert Scale to 100 respondents in Indonesia with purposive sampling method. To explain the relationship between the dependent variable and independent variables, Path Analysis is used to measure the questionnaires. The result of this study finds that perceived cost and compatibility are significantly related to the consumers adoption of electronic payment, with compatibility as the strongest factors that influence consumers adoption of electronic payment. This research aims to be useful for the electronic payment service providers to develop their services for their consumers, especially in the context of Indonesian's market.


The traditional set theory is constructed on the steady state, the bivalent logic and the fixed set boundary. However, the development of fuzzy set or rough set inspires us that an element, which membership degree to a specified set could be multivalent (fuzzy set) and the set boundary could also be undetermined (rough set). No mattering from the scope of traditional set, fuzzy set or rough set, the element is belonged to a specified set or not is assumed as a steady (time-independent) behavior. Thus, we may regard these aforementioned set theories as the time-independent set theories. In this study, we explore the possibility of proposing a time-dependent set theory, which means the relation between two objects we consider it should be time- dependent: we name it the affinity set theory. We present a simple framework for the concept of affinity based on fuzzy set theory. The notion of affinity set is introduced. A new forecasting method based on game theory and affinity set is also presented.


Mixed finite element methods are applied to a fourth order reaction diffusion equation with different types of boundary conditions. Some a priori bounds are established with the help of Lyapunov functional. The semidiscrete schemes are derived using C0‐piecewise linear finite elements in spatial direction and error estimates are obtained. The semidiscrete problem is then discretized in the temporal direction using backward Euler method and the wellposedness of the completely discrete scheme is discussed. Finally, a priori error estimates are established. While deriving a priori error estimates, Gronwall's lemma is applied and the constants involved in the error bounds do not depend exponentially on \documentclass{article} \usepackage{amsmath, amsthm, amssymb, amsfonts}\pagestyle{empty}\begin{document}$\frac{1}{\gamma}$ \end{document}, where γ is a parameter appeared in the fourth order derivative. © 2011Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2012


Aiming at the reliability index calculation of a strong nonlinear structural performance function,the numerical sampling and regression analysis methods are introduced to analyze the second-order expansion of a modified performance function.Thereby the form of general law between SOSM reliability index βSORM and FOSM reliability index βFORM is obtained.On the basis of a regression analysis-prediction algorithm,a new reliability analysis method is presented according to the general law above and the application of a line sampling Monte Carlo method.Through the regression analysis of certain sampling points,the proposed algorithm can establish the specific expression of a general law between βSORM and βFORM.And the high precision solution of a strong nonlinear performance function reliability index can be achieved.The study results show that a cumbersome calculation and an inefficient iteration can be alleviated effectively by the present algorithm.The advantages of the present method in accuracy,application scope and calculation stability are obvious.Because of its convenience and intuition,the present algorithm is easy to be mastered by general designers and applied to an actual engineering analysis.


Rudists are important macrofossils in the Upper Cretaceous of the Adriatic Carbonate Platform. Among them, hippuritids are common, particularly in the Santonian of southern Istria (MORO, 1997; MORO & ĆOSOVIĆ, 2000) where they have been used for detailed biostratigraphy (POLŠAK, 1965; POLŠAK et al., 1982). POLŠAK (1965, 1967) recognised seventeen species (Table 1) based on morphological characteristics (S and E pillars, shell thickness, visceral cavity and ornamentation). Determination of the species within the family today is based on a combination of morphological elements (ligamental ridge, teeth, and pillars). The sector L–P1–P2, i.e. ligamental ridge and pillars of the lower valve (DECHASEAUX & COOGAN, 1969) are also very important for identification. A Proposal for Taxonomic Re-Evaluation of Vaccinites Species from the Santonian Limestones of Southern Istria (Croatia)


Modifications are described to the electron multiplier pre-amplifier, selected ion monitor, magnet current supply and scan controller of the LKB 9000S gas chromatograph mass spectrometer. The modifications described have secured an improved performance for specific ion monitoring and fast repetitive scanning gas chromatography mass spectrometry.


ree deaths are often dramatic events. Fires can consume thousands of hectares of forest in a single conflagration. The powerful winds of hurricanes and tornados can flatten all the trees in their paths. More subtle events of synchronous tree mortality, such as those caused by defoliating insects or fungal diseases, may attract attention because of the ghostly skeletons that remain. But these dramatic forms of tree mor-


From the Publisher:
Logic has acquired a reputation for being difficult, perhaps because many of the approaches adopted have been more suitable for mathematicians than computer scientists. This book shows that the subject is not inherently difficult and that the connections between logic and declarative language are straightforward. Many exercises have been included which will lead to a much greater confidence in manual proofs, in turn leading to a greater confidence in automated proofs.


According to experiences,it introduces design of long-line pedestal,and illustrates construction of pre-tensioned pre-stressing beam and long-line pedestal from selection of facility、stretch-draw of steel strand、pouring of concrete and collocation of pre-stressing bar,technical measures for quality safety are putted forward.


This chapter on pediatric infectious diseases first presents patient scenarios, followed by a question-and-answer format to provide active learning to emphasize key points regarding clinically relevant topics, which are also covered in the American Board of Pediatrics Content Outline for certification exams. The topics addressed in this chapter range from common infectious processes encountered by pediatricians to more unusual, but important, conditions. Specific topics include infections in immunocompromised hosts, sepsis, central nervous system infections, respiratory infections, gastrointestinal infections, hepatitis, bone and joint infections, regional mycoses, parasites, sexually transmitted infections, infections in neonates, management of antimicrobial agents, pediatric HIV-1, and immunizations.


In the study of solar sensible heat and storage heat material,although the performance of gravel is general,because of its cheap and easy to get,it has a wide range of applications.In this paper,by studying the basic structure of gravel bed and its storage heat technology,we gave heating principle design by using the gravel bed storage heat technology,and discussed the heat transfer theoretical formula of gravel bed.


Sometimes it is not enough for a DNN to produce an outcome. For example, in applications such as healthcare, users need to understand the rationale of the decisions. Therefore, it is imperative to develop algorithms to learn models with good interpretability (Doshi-Velez 2017). An important factor that leads to the lack of interpretability of DNNs is the ambiguity of neurons, where a neuron may fire for various unrelated concepts. This work aims to increase the interpretability of DNNs on the whole image space by reducing the ambiguity of neurons. In this paper, we make the following contributions:
1) We propose a metric to evaluate the consistency level of neurons in a network quantitatively.
2) We find that the learned features of neurons are ambiguous by leveraging adversarial examples.
3) We propose to improve the consistency of neurons on adversarial example subset by an adversarial training algorithm with a consistent loss.


The influence of structural defects in the formation of silver nanoplates synthesized by the photochemical seed-mediated method is addressed. The results show that anisotropic growth starts at the very beginning of the reaction by epitaxial anisotropic deposition of Ag atoms on defective seeds. Insights into the role of capping molecules and the minor role played by surface plasmon excitation regarding the origin of the anisotropy in this method are provided.


Objective To investigate the clinic pathological characteristics and histogenesis of sclerosing hemangioma of the lung(SHL).MethodsThe clinicopathological features of 5 sclerosing hemangiomas were analyzed.Using immunohistochemical methods,the expression of TTF-1,CK7,EMA,AEl/AE3,CK5/6,Vimentin,CD31,CD34,S-100,CgA,Syn,NSE,Calretinin,ER,PR and Ki-67 were observed in 5 cases of SHL.ResultsSHL exhibited the following histological features: papillary,sclerotic,solid,hemorrhagic,and mixed.The majority of tumors showed a mixed pattern of histology.The tumor is composed of two distinct cellular components,the round or polygonal or stroma cells and the cuboidal or surface cells.Immunohistochemical staining revealed the both kinds of cells expressed TTF-1 and EMA,the cuboidal cells expressed AEl/AE3 and CK7,the round or polygonal cells expressed vimentin.ConclusionSclerosing hemangioma exhibits various histologic findings,which probably originated from the epithelial cell of primary respiratory tract.Immunohistochemistry is helpful to dignosis.


THIRTY YEARS have elapsed since von Euler and Liljestrand advanced the proposition that acute hypoxia elicits pulmonary vasoconstriction. The idea was not new,' but the report excited considerable interest because it was both propitious and prescient. Nineteen forty-six was a good year to perceive that the pulmonary vasoconstrictor response to hypoxia is part of a self-regulatory mechanism by which pulmonary capillary blood flow is automatically adjusted to alveolar ventilation: methods had been standardized for exploring the pulmonary circulation in a systematic and sophisticated way and the introduction of cardiac catheterization had brought the previously remote pulmonary circulation within reach. Much has been learned since then about the pulmonary circulation and the pressor response to acute hypoxia. Particularly helpful in dispelling the original misgivings about the occurrence of a pressor response to acute hypoxia has been a succession of observations on cattle in which the pulmonary pressor response to hypoxia is much greater than in the conventional laboratory animal, particularly in the postnatal period." That pulmonary vasoconstriction underlies the rise in pulmonary arterial pressure no longer is in doubt.The biological significance of this mechanism has been sought both in human disease and in animals."' And, the lessons from acute hypoxia have been extended to the chronic hypoxia of high altitude which also has proved to be associated with pulmonary vasoconstriction.' 15 As uncertainty after uncertainty evaporated, two key questions came into sharp focus: (1) By what mechanism(s) does hypoxia elicit vasoconstriction? (2) What segment(s) of the pulmonary vascular tree constrict(s) during hypoxia? The purpose of this paper is to offer a personal view of the answers to these questions. And, after having proposed how and where acute hypoxia works, brief consideration will be given to the question of how the observations on acute hypoxia—generally an artifice of the laboratory—are related to the state of chronic hypoxia which characterizes life at high altitude.


This paper presents one aspect of a sociocultural micro-ethnographic study examining how 11- and 12-year-old children formulate meanings when working with an artist in a contemporary art gallery. My primary focus is an examination of methodological contributions emerging from an imaginative coding and analysis of children's art. Ninety-nine artworks were created in collaboration with the artist and were organised and interpreted using a constructionist interviewing coding scheme. This unorthodox approach to visual analysis unearthed information that oral accounts cannot provide alone revealing meanings which would otherwise remain dormant. By intuitively applying the coding framework I expose how participants' meanings are negotiated by appropriating and re-organising cultural concepts into personalised narratives. As such, artworks reveal participants' desires, interpretations and intentions, operating as agentic cultural producers as well as unconsciously reproducing visual epistemologies ubiquitous in Western cultures.


The synthesis of the 3′-fluoro-derivatives of 5-amino-1-(β-D-ribofuranosyl)imidazole-4- carboxamide (AICA-riboside) and the isomeric 4-amino-1(β-D-ribofuranosyl)imidazole-5- carboxamide (iso-AICA-riboside) are described. Structures were confirmed by elemental analysis, UV and 1H NMR spectroscopy. The anti-viral and anti-cancer activities of these imidazole nucleosides were tested.


Smart home is a promising paradigm and technology for providing the ability to physical objects to operate over the Internet. While this technology provides convenience to its users a number of initiatives across the globe are taken in academia and industry to deal with security issues that it may entail. Among these is the issue of interdevices authentication in the presence of security threats such as vulnerability of session/cookies. In this paper two passphrase protected device‐to‐device (D2D) mutual authentication schemes for smart homes are proposed where the keys are protected using passphrases and a centralized server provides proxy‐passphrase service to smart home devices assuming that the server keeps the database of passphrases as well as the servers' passphrase‐proxy service. The high‐level protocol specification language (HLPSL) language is used to model the proposed two protocols and a security analysis is conducted using the security protocol animator for AVISPA (SPAN)/AVISPA (Automated Validation of Internet Security Protocol and Applications) tool showing that the proposed schemes can achieve the goals of secrecy of secret keys and D2D mutual authentication


Objective To analyze both maternal and fetal effects of expectant treatment of early-onset severe preeclampsia,and discuss recommendable treatment choices based on the balance of both effects.Methods To review the 128 cases of early-onset severe preeclamosia treated in our hospital from July 2008 to June 2011,divided into three groups according to gestation weeks when hospitalized: Group A with 27 cases less than 29 weeks,Group B with 49 cases of 29~31+6 weeks,Group C with 52 cases of 32~34 weeks.Results Group B had the longest average treatment time while Group A shorter and Group C the shortest;pregnancy complications ratio of Group C is significantly different(P0.05) from Groups A and B,whereas no significant difference(P0.05) between Groups A and B;and the poor perinatal outcome ratios are significantly different(P0.05) among the three groups,with Group C the best and Group B poorer and Group A the poorest.Conclusion On balanced consideration,patients of less than 29 gestation weeks,when afflicted with pregnancy complications,might advisably choose to terminate pregnancy,while those of 29~31+6 weeks might choose to stay on expectant treatment for longer gestation time and better perinatal outcome,and those of 32~34 weeks should make more efforts to prolong gestation time to further improve the perinatal outcome.


A series of 3-thiosemicarbazono-2-indolinones and 3-(4-thiazolidone-2-hydrazono)-2-indolinones was synthesized by condensation of various isatin derivatives with 4-substituted 3-thiosemicarbazides and cyclization of the products by monochloroacetic acid or ethyl alpha-bromoacetate. In the present work we report on the structure determination and anticonvulsant evaluation of the title compounds.


Quantum dense coding transmits classical information by sending a quantum system with the assistance of quantum entanglement. The classical information capacity of a quantum dense coding system is obtained, where a sender and receiver share a completely entangled state and a quantum system encoded by applying unitary operators is sent through an arbitrary quantum channel. The result is compared with that obtained in another setting.


Abstract : Calculations and analyses are presented to demonstrate the feasibility of inverting multi-frequency brightness temperature measurements obtained with an oxygen-band radiometer to recover the average kinetic temperature profile of the atmosphere. Special attention is given to cloud effects, radiation from above the atmospheric model, radiative-transfer equation solutions, effects of radiometer measurement errors on the profile recovery accuracy, and the selection of optimum observing frequencies. Recovered temperatures could be used to calculate pressure altitudes, which for a network of ground stations would provide the pressure gradient for calculating winds aloft. Such information is required for long-term numerical weather forecasting. (Author)


Study Design We evaluated a computer-assisted surgical tool for inserting pedicle screws. Objectives This study reviewed the feasibility, usefulness, and accuracy of the proposed tool. Summary of background Data Reviews documented neurovascular damage caused by screw misplacement. Currently, screw hole position is assessed by radiologic means and curette palpation. Methods Three sheep vertebrae and one artificial object were reconstructed three-dimensionally from computed tomography scan slices. At surgery, the surgeon's movements were displayed relative to the three-dimensional vertebrae on a computer screen. The tool was used to detect pedicles and to verify the position of drilled holes, In our laboratory, we calculated the system's accuracy by taking measurements on the artificial object. Results All pedicles were identified with the computer. Five of the six drilled hole positions were correctly represented. An accuracy of 4.5 mm ± 1.1 mm RMS (root of the mean squared) and 1.6°± 1.2° were calculated. Conclusions Results suggested the proposed system could be useful for pedicle detection and assessing the intravertebral location of drilled hole. The proposed system could be used for many different orthopedic procedures where structures are hidden from the surgeon's view.


We consider powers of lexsegment ideals with a linear resolu- tion (equivalently, with linear quotients) which are not completely lexseg- ment ideals. We give a complete description of their minimal graded free resolution.


The present invention relates to a hybrid brake system having a pedal simulator of the parallel structure. Hybrid braking device in accordance with the present invention an input shaft connected to a brake pedal; The pedal simulator control plunger connected to the input shaft which is provided on the inner side; In communication with the pedal simulator, and the first and the second master cylinder piston therein; Five days supply for supplying oil to the pedal simulator and the master cylinder; And, it arranged to be in communication with the pedal simulator, and the boosting unit to form a reaction force when the brake pedal pressed; characterized in that it comprises a.


Interspecies hybridization has been widely used in the development of aquaculture in fish species but there is not much impact in crustacean species. Several species of crustaceans that have been successfully crossed still have low hatching rates and the hybrids obtained have not met expectations. This review tries to summarize and analyse interspecific hybridization of cultured crustacean species (shrimps, lobsters, crayfish and crabs) and its potential for development of crustacean aquaculture production. The success of cross‐breeding on several species of shrimp and lobster has been supported by artificial insemination technology. In crabs, artificial insemination cannot be applied and cross‐breeding still relies on natural mating with an unstable success rate. In addition to cross‐breeding in captivity, cross‐breeding of crustacean species (shrimp, lobster, crayfish and crab) in nature has also been found. Interbreeding of crustacean species in nature cannot always be distinguished morphologically, hybrids between them can be known with certainty after carrying out molecular analysis. Even though the level of reproductive performance in cross‐breeding of shrimp, lobster, crayfish and crab species is still low, cross‐breeding efforts must be continued to obtain more information so that it can later be mapped which species have the potential to develop hybrids for cultivation. Furthermore, growth, reproductive performance, monosex hybridity and disease resistance are all hybrid parameters that must be evaluated.


Different types of EMS in continuous caster and their influences on strand quality are reviewed.Considerations to select appropriate type of EMS are introduced according to the requirement on metallurgical quality to the cast strands for different steel grade.Metallurgical effects of M-EMS on both billet and round bloom casters at Maanshan Steel are analyzed and countermeasures to existing problems are put forward accordingly.


Objective To discuss the expression and significance of hypoxia-inducible factor-1α(HIF-α) in rat lung ischemiareperfusion injury. Methods 24 healthy male rats from Shenyang Medical College Experimental Animal Center were divided into three groups, group A, group B and group C. 24 h before the establishment of ischemia-reperfusion injury model, group A were given intraperitoneal injection of normal saline, group B were given the injection of DMOG, group C were only given left thoracotomy without ischemia-reperfusion treatment. Results Group A showed significant lung injury; the expression of HIF-1α protein increased and the average gray value decreased in group A and group B at each time point; the IL-8 and MDA content increased and SOD activity decreased in group A and group B at 1h and 6h after the reperfusion; the IL-8 and MDA content increased and SOD activity decreased in group A and group B 6h after the reperfusion(P0.05). Conclusion Regulation of the activity of HIF-1αcan protect the ischemia-reperfusion lung, which provides a new idea for the treatment of lung ischemia-reperfusion injury.


Patients with diabetes suffering from peritoneal surface disease represent a challenge to treat due to the effects of both processes on multiple organ systems. We sought to define the impact of diabetes on outcomes following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC).


ABSTRACT A disease of the motor neuron, the Lateral Amyotrophic Sclerosis causes a fast (up to mean five years), progressive and inexorable muscular atrophy. There are several theories regarding its etiology, which is believed to be multifactorial; it's clinical presentation differs according to the patient, concerning to signs, symptoms, severity and course. The current treatment is multidisciplinary e basically palliative, with medium survival enhance. The future perspectives for the treatment are based on steam cells and growth factors.


Law enforcement practice reveals difficulties in establishing a wide range of circumstances in investigating and solving crimes committed in the sphere of agro-industrial complex. The reality requires the participation of the executive authorities' officials in monitoring and supervising subjects involved in this area.
The purpose of the study is to analyse the problematic aspects of determining forms and kinds of interaction in investigating and solving crimes.
The author also substantiates the need to combine different methods and means in investigating and solving crimes committed in the agro-industrial complex.
The analysis is based on the systematic approach, as well as on the methods of analogy, documents examination.
The patterns of investigating and solving crimes committed in the agro-industrial complex predetermine the need to clarify certain theoretical provisions related to highlighting forms and types of interaction. The peculiarity of interaction seems to be in a rational combination of means and methods that law enforcement agencies' and state bodies' officials monitoring and supervising agro-industrial activities are endowed with. The formation of scientifically-based recommendations related to the research subject is build upon the specifics of the legal, organizational and tactical aspects of interaction at the departmental and interdepartmental levels.


Self‐efficacy, or a person's situation‐specific belief that s/he can succeed in a given task, has been successful in a variety of educational studies for predicting behaviors such as perseverance and success (grades), and for understanding which behaviors are attempted or avoided. The focus of this study was to examine if classroom factors such as teaching strategies and classroom climate contribute to students' physics self‐efficacy. 121 undergraduates in first semester, calculus‐based introductory physics courses completed surveys assessing course experiences, self‐efficacy and other outcome variables, and demographic information. Students in sections including a mix of teaching strategies did significantly better than students in the traditional section on outcome variables including self‐efficacy. When individual strategies were examined, the strongest relationships were found between cooperative learning strategies and all sources of self‐efficacy, and between climate variables and all sources of eff...


In The Social Foundations of Postindustrial Economies (Oxford University Press, 1999) Gosta Esping-Andersen presents a classic example of an empirically grounded historically materialist analysis of welfare capitalism, in the tradition of Polanyi, Marshall and others. He argues that its architecture needs to be re-thought because of the changing nature of postindustrial economies and that this requires us to think in terms of 'welfare regimes' comprising the market, the state and the family. When the welfare state finally reached its mature institutional expression, as late as the 1960s and 1970s, it addressed the risks which had typically been faced by families in the 'Golden Age' of capitalism in the long post-war boom. This meant protecting prime age men employed in Fordist industries earning family wages from spells of unemployment and older men from decreased earning power. Protecting the male breadwinner was also meant to protect those dependent upon him. The bulk of income transfers were thus focused on old age pensions and unemployment insurance. There was little in the way of service provision: 'familialism' left reproductive work such as child or elder care to the unpaid work of women in families.


Objective To observe the effects of sulfentanil combined with droperidol in patients controlled intravenous an algesia(PCIA).After breast operation,determine the best concentration of sulfentanil.Methods Ninety patients after breast operation were randomly divided into three groups with 30 cases each.The patients in group S1 received 1.0 μg/ml sulfentanil plus 50 μg/ml droperidol.In group S2,1.2 μg/ml sulfentanil plus 50 μg/ml droperidol.In group S3,1.5 μg/ml sulfentanil plus 50 μg/ml droperidol.PCIA parameters were a bolus dose of 2 ml,lock out interval of 30 minutes and continuous infusion of 2 ml/h.Visual analogue scales(VAS)and adverse effects were observed at 4,8,12,24 and 48 h postoperatively.Results Pain score was higher in group S1 than that in group S2 and group S3(p0.05 or 0.01).There was no significant difference between group S2 and group S3.Sedation score and the incidence of adverse effects such as nausea and vomiting were lower in group S1 and group S2 than that in group S3(p0.01).Conclusion PCIA with 1.2 μg/ml sulfentanil combined with droperidol can provide a good postoperative analgesia and use safely in spinal surgical patients.


SUMMARY This paper proposes a novel one-way hash function that can serve as a tool in achieving authenticity and data integrity. The one-way hash function can be viewed as a representative of a family of fast dedicated one-way hash functions whose construction is based on linear cellular automata over GF(q). The design and analysis of security of the function is accomplished by the use of very recently published results on cellular automata and their applications in cryptography. The analysis indicates that the one-way hash function is secure against all known attacks. A promising property of the proposed one-way hash function is that it is especially suitable for compact and fast implementation.


As a result of deinstitutionalization, more persons who are carriers of hepatitis B are attending public school classrooms for persons with handicaps. The behaviors demonstrated by some members of this population increase the risk of hepatitis B to both other students and staff. This article discusses the transmission and prevention of hepatitis B and the implications of the disease for special educators. Several administrative and legal issues of concern to special educators, administrators, students, and parents are presented.


Heating and humidification control during mechanical ventilation is impor-tant. Water condensation can occur due to insufficient humidification. Condensation in the breathing circuit can cause various adverse events. In this study, we investigated whether the occurrence of tubing condensation in the breathing circuit could be affected by room temperature using a simulated respiratory circuit with a humidifier. The room temperature was set at 23˚C, 25˚C, and 27˚C, and mechanical ventilation was performed for 8 h. The inspired gas was appropriately heated and humidified according to the manu-facturer's instructions. The weight of the circuit was measured every 2 h at room temperature to estimate the amount of condensation. During the mechanical ventilation, condensation continued to increase at a room temperature of 23˚C, but only for the first 2 h at 25˚C, and did not occur at 27˚C. The room temperature of the indoor environment was one of the factors generat-ing water condensation in the breathing circuit with a humidifier even when a heater wire in the breathing circuit was appropriately operated.


It has been 30 years since Wennberg and Gittelsohn published their landmark article demonstrating substantial variation among different geographic areas in the provision of medical services.1 Since then, investigators have found variation in the delivery of virtually every aspect of health care that has been examined. From the perspective of the quality of care, the variation that is the greatest cause for concern is that between actual practice and evidence-based "best practice." Over the past 30 years, progress has been made in several areas that are vital to quality improvement. Practice guidelines have become more rigorously evidence-based and are now . . .


The Federal Coal Mine Health and Safety Act of 1969 delegated to the Bureau of Mines a yearly program of health inspections. Respirable coal mine dust concentrations are measured by Bureau inspectors. Samples of respirable coal mine dust are weighed to determine dust concentration and then analyzed for ash and quartz content. This paper describes the laboratory procedure for determining the percent quartz in the respirable coal mine dust samples.


Background: Accelerometers are used to objectively measure movement in free-living individuals. Distinguishing nonwear from sleep and sedentary behavior is important to derive accurate measures of physical activity, sedentary behavior, and sleep. We applied statistical learning approaches to examine their promise in detecting nonwear time and compared the results with commonly used wear time (WT) algorithms. Methods: Fifteen children, aged 4–17, wore an ActiGraph wGT3X-BT monitor on their hip during overnight polysomnography. We applied Hidden Markov Models (HMM) and Gaussian Mixture Models (GMM) to classify states of nonwear and wear in triaxial acceleration data. Performance of methods was compared with WT algorithms across two conditions with differing amounts of consecutive nonwear. Clinical scoring of polysomnography served as the gold standard. Results: When the length of nonwear was less than or equal to WT algorithms' predefined thresholds for consecutive nonwear time, GMM methods yielded improved classification error, specificity, positive predictive value, and negative predictive value over commonly used algorithms. HMM was superior to one algorithm for sensitivity and negative predictive value. When the length of nonwear was longer, results were mixed, with the commonly used algorithms performing better on some parameters but GMM with the greatest specificity. However, all approached the upper limits of performance for almost all metrics. Conclusions: GMM and HMM demonstrated robust, consistently strong performance across multiple conditions, surpassing or remaining competitive with commonly used WT algorithms which had marked inaccuracy when nonwear time periods were shorter. Of the two statistical learning algorithms, GMM was superior to HMM.


Bilevel programming problems are hierarchical optimization problems where an objective function is to be minimized over the graph of the solution set mapping of a second parametric optimization problem. It is the aim of the paper to give a survey for this living research area indicating main recent approaches to solve such problems and to describe optimality conditions as well as to touch main particularities of this problem class.


Encryption is an effective way of protecting sensitive data that have been outsourced in the cloud computing environment. But it is computationally expensive for the database management system to carry out SQL queries against the encrypted data. A query conversion scheme is presented which converts traditional database queries to encryption specific versions so that the queries can be directly executed on the cloud server. This scheme dramatically increases the efficiency of query processing in encrypted cloud databases, and it provides high transparency for end users by introducing a SQL gateway to the user applications and the cloud server.


We study the problem of computing angle domain gathers via the least squares migration technique for shot-profile migration. For this purpose, one can compute angle gathers by estimating a reflectivity function that depends on angle of propagation. A polynomial interpolation method is adopted for constructing an operator that maps shot dependent reflectivity to a reflectivity model that depends on propagation angle. The angle of propagation is estimated by forward modelling the source-side wavefield on the smooth background migration velocity model. Specifically, the gradient of the sourceside wavefield is used to estimate the angle of propagation. Finally, a pair of migration and demigration operators that pass the dot product test (to guarantee adjointness) are used in conjunction with the method of conjugate gradients to solve the least squares migration problem.


Recently, the issue on the competitive modeling in judo has aroused the interest of researchers since it provides important indications for the preparation and monitoring of athletes performance. Although some studies about judo competitions have been developed, there is still lack of information about classes of young athletes in this sport. Therefore, the present study investigated the stimulation time and pause, standing stimulus, stimulus on the ground, fi ght total, total stimuli, total pause and also the number of stimuli and pauses in judo competition. In this study we used the video recordings of 36 state youth-class judo championship fi ghts in the state of Sao Paulo, which data were described through centrality and dispersion measurements. The main results showed that the mean values (in seconds) of the total duration of the fi ght were 160 ± 145, the time of stimulation was 19 ± 12 and the time of pause was 11 ± 12. The amount of stimuli standing up was four, whereas that on the ground was one and a half per fi ght. These data show that the time structure in junior-class fi ghts has short and intermittent stimuli, in which the time stimulus is higher than that of pause. Such details are found to be important both for the development and monitoring of the training.


Provided are: an adhesive composition for a touch panel, comprising acrylic resin, a first curing agent having one to three functional groups, a second curing agent having four to six functional groups, and an ultraviolet blocking agent containing a benzotriazole group; and an adhesive film for a touch panel, comprising a cured product of the composition.


A review of various approaches to the problem of the proton spin is presented. Arguments are given in favor of the idea that the answer to the "spin crisis" is to be found in fundamental nonperturbative properties of the QCD vacuum.


Laser angioplasty is one of the catheter treatments of atherosclerosis that is suitable for difficult-to-treat lesions such as in-stent restenosis and total occlusions. In clinical practice, excimer laser coronary angioplasty has been applied. However, conventional XeCl excimer laser (wavelength: 308 nm) have the risk of injuring normal vessels [1]. Therefore, safer laser devices have been required.


The present invention relates to a method and mobile terminal for changing the communication mode, to a method for changing a communication mode for reducing the power consumption of the mobile terminal to increase the standby time of the portable terminal and the portable terminal. According to the invention, a method for changing a communication mode of a wireless terminal is that the step of determining if the communication mode is set upon receipt of connection signals with the external device is a bi-directional mode, it is determined that the communication mode is not a two-way mode, a one-way mode is determined If the step is determined that the communication mode in which a one-way mode, characterized in that it comprises the step of performing the external device and paging. A wireless terminal, a one-way communication, one-way, communication, local communication section


This paper studies the model of variable-speed pitch-controlled wind turbine, and establishes its mathematical model. Based on this model, For extracted maximum power from the wind, a kind of multi-controller with speed and pitch controller is designed. The model and its control system is studied and simulated in with Matlab.


sible to obtain pure preparations of a certain protein fraction.5 However, the accumulated evidence so far favours the view that macroglobtulins are abnormal proteins for three reasons: 1. In spite of excessive amounts of gamma globulins, resistance to infections is frequiently diminished. 2. It has been pointed out that some macroglobulins are quite different immunochemically from the gamma globulins found in normal plasma.', 1> 3. The carbohydrate content in the molecules of macroglobulins is always quite high compared with other globulins, especially the ones fouind in multiple myeloma.12 Quiite a number of so-called secondary macroglobulinamias have been reported in cases of multiple myeloma, sarcoidosis, nephrosis, lymphosarcoma, subacute bacterial endocarditis, chronic lymphatic leukemia, atypical lymphatic hyperplasia, cancer of the uterus, the skin and the lungs, hepatoma, Sjogren's syndrome, disseminated lupus erythematosus, and congenital syphilis. The pathogenetic relation of these conditions to macroglobulinemia is mainly a matter of conjecture. That these conditions, however, are not purely coincidental with macroglobulinamia was proven by Abrams, who succeeded in extracting macroglobulins from lymphosarcoma tissue.23 Although on autopsy of our case evidence of old endocarditis was found, there was no evidence of activity of this process. Clinically, there were no symptoms directly attributable to the syphilitic aortitis or the minimal demyelinization of the posterior columns. It was interesting to note that, in spite of the evidence for syphilis, the treponema pallidum immobilization test was negative in the peripheral blood. The bone marrow findings were quite consistent with those reported in the literature. It is claimed that the plasma cells and also probably the lymphocytes are most likely the source of the abnormal globulins. XWaldenstrbm implied in his original paper that the disease, which he later described as macroglobulinamia, might represent an "incipient myelomatosis". A number of pathologistsl6 share the view that these hyperglobulinemias are in fact plasma cell myelomas which have escaped detection because of the diffuse natuire of the distribution of plasma cells. Other authors think that macroglobulina;mia represents a reticulosis, which wouIld include myelomatosis and lymphatic leukaemia on the one end and purpura hyperglobulinemica on the other. As in our case, a number of patients in the literature succumbed to acute infections and had signs of chronic infection for longer periods. Some authors23 therefore consider macroglobulinaemia to be one of the allergic manifestations of chronic infection, in which the reticuloendothelial system becomes sensitized, resulting in an increased protein produ}ction. Anotherconcept was advanced by Waldenstrdm23 recently, in which macroglobulin,mia is considered to be a "molecular disease" and an equivalent to a somatic mutation.


This paper aims to understand what being cosmopolitan entails by delving into three texts- The Woman Warrior, My Beautiful Laundrette and The In-Between World of Vikram Lall. Each text will discover different aspects of national identity and the contrast it presents to the modern understanding of the term cosmopolitan. The paper will raise questions on what nationalism means in


Processing apparatus includes pretreatment of a sample analysis device (110), and means for any one sample (120); means for managing management apparatus (130), management means (130) comprising: abnormality detecting means (137) which detects errors occurring in the apparatus; and a storage unit (135), which stores an operator notification management table (136), the operator notifies the management table for each type of error log at least one operator; abnormal a notification unit (134) (137) detects abnormality detection unit kind of error to notify the management table (136) based upon the operator, a response operator notifies an error to be; and registration means (133), which is log from abnormality notification unit (134) is notified by the erroneous operation of the operator to deal with errors, i.e. responders. Accordingly, even when the error analyzing means, processing means, and the like occurs, it is possible to share information by whom response.


What is the level of nationalization of political parties and of the Brazilian party system? In this paper, we use the Jones and Mainwaring (2003) measure to assess the degree to which electoral support from political parties is homogeneous among state federative units. For that, we used data from the electoral disputes for the Chamber of Deputies between 1998 and 2014 made available by the Superior Electoral Court (TSE). Methodologically, we calculated the index of nationalization based on the distribution of party votes by state and described the data based on descriptive statistics techniques and graphical tools. The results of this work indicate that the Brazilian party system seems to be structured among the three largest parties with representation in the Federal Chamber of Deputies: PMDB, PT and PSDB. However, this does not mean that these parties are large in all units of the federation.


The preceding reports in this series ( i i , 7) recorded studies of the peripheral blood pictures of normal, pregnant, and lactating rats of several inbred strains and of rats injected with two carcinogenic chemicals, methylcholanthrene and benzpyrene. The present report is based on a series of observations of rats with methylcholanthrene and benzpyrene tumors and of rats with progressively growing transplanted tumors of diverse origin. The material and methods used are described in the first two papers. There were 223 average age for each group and the average interval between the first and subsequent blood tests. Table I includes the data on Iog tumor rats that had been injected with I to 3 mgm. of methylcholanthrene. The mean values before injection were: hemoglobin i4.8 gm. per Ioo cc., and red cells 8.6 million and white cells I4.2 thousand per cu. mm. The differential values were: 2 9 per cent polymorphonuclear neutrophil leucocytes, 6 5 per cent lymphocytes, 4 per cent monocytes, and 2 per cent eosinophils.


The Web has evolved into a huge mine of knowledge carved in different forms, the predominant one still being the free-text document. This motivates the need for Intelligent Web-reading Agents: hypothetically, they would skim through disparate Web sources corpora and generate meaningful structured assertions to fuel Knowledge Bases (KBs). Ultimately, comprehensive KBs, like Wikidata and DBpedia, play a fundamental role to cope with the issue of information overload. On account of such vision, this paper depicts the FACT EXTRACTOR, a complete Natural Language Processing (NLP) pipeline which reads an input textual corpus and produces machine-readable statements. Each statement is supplied with a confidence score and undergoes a disambiguation step via entity linking, thus allowing the assignment of KB-compliant URIs. The system implements four research contributions: it (1) executes N-ary relation extraction by applying the Frame Semantics linguistic theory, as opposed to binary techniques; it (2) jointly populates both the T-Box and the A-Box of the target KB; it (3) relies on a lightweight NLP machinery, namely part-of-speech tagging only; it (4) enables a completely supervised yet reasonably priced machine learning environment through a crowdsourcing strategy. We assess our approach by setting the target KB to DBpedia and by considering a use case of 52, 000 Italian Wikipedia soccer player articles. Out of those, we yield a dataset of more than 213, 000 triples with a 78.5% F1. We corroborate the evaluation via (i) a performance comparison with a baseline system, as well as (ii) an analysis of the T-Box and A-Box augmentation capabilities. The outcomes are incorporated into the Italian DBpedia chapter, can be queried through its SPARQL endpoint, and/or downloaded as standalone data dumps. The codebase is released as free software and is publicly available in the DBpedia Association repository.


This paper presents an integrated single-vendor two-buyer production-inventory model with stochastic demand and service level constraints. Shortage is permitted in the model, and partial backordered partial lost sale. The lead time demand is assumed follows a normal distribution and the lead time can be reduced by adding crashing cost. The lead time and ordering cost reductions are interdependent with logaritmic function relationship. A service level constraint policy corresponding to each buyer is considered in the model in order to limit the level of inventory shortages. The purpose of this research is to minimize joint total cost inventory model by finding the optimal order quantity, safety stock, lead time, and the number of lots delivered in one production run. The optimal production-inventory policy gained by the Lagrange method is shaped to account for the service level restrictions. Finally, a numerical example and effects of the key parameters are performed to illustrate the results of the proposed model.