In this paper,the research process of quasi-one dimensional nanostructure materials synthesized by gas-solid reaction is reviewed,and the difference between gas phase thermal chemical synthesis and gas-solid reaction is introduced in briefly.The preparation process and the growing mechanism of quasi-one dimensional nanostructure materials (including oxide and sulfide) using gas-solid reaction,that is oxidizing or sulfurizing metal,e.g.Cu、Fe、Zn,etc.directly are then described in detail.The potential application of quasi-one dimensional nanostructure materials is also presented.


The present invention discloses a low-power system and the intelligent electronic price implementation method, characterized by comprising a first zone controller wireless transceiver unit, a second wireless transceiver unit and the third wireless transceiver, second wireless transceiver unit no-ACK and the reception mode and in a second frequency band, a third wireless transceiver unit transmits the no-ACK mode and operate in a second frequency band, is responsible, can avoid multiple tags simultaneously generate data collisions when communication with the communication zone controller and the electronic price tag cause packet loss problem; first wireless transceiver unit operating with an ACK and automatically operate in a first frequency band, responsible for receiving the electronic price tag currently displayed information, and a gateway uplink and downlink data interaction, since the second operating band different / three radio transceiver unit, when the working frequency hopping techniques, frequency interference can be avoided when the data update tag, which can effectively prevent packet loss during the data transmission.


Book review of Linda Rhodes' book Two for the Price of One, The lives of Mining Wives. Rhodes has documented the general aspects of life as experienced by mining wives and provided an in-depth critical analysis of one group of mining wives. She details the history of women in mining from its commencement in Australia's early colonial period, through the years of large scale development and extreme change in the 1960s, 70s and 80s to very recent times from a range of source materials. The narratives of women who are wives of metallurgists, engineers and geologists compliment the source material presented. I conclude that Linda Rhodes book is an interesting read.


Even though it is expected the industry on new media contents will be grown constantly, corporate feels that the related specialists, human resources are so lack and it is real that the specialty level on related personnel, skilled works is low. In current situation, it is essential that the active supports will be given to new media contents industry with constant high quality human resource development as a winning point to success. Therefore the curriculum development must be reflected the current field situation in this industry for the human resource to meet the field corporate requirements. The DACUM method is used to develop the curriculum on this study in order to develop the college level human resources who have active adoptability to corporate in new media contents industry.


There has been a global explosion of freedom of information(FOI) laws in the last two decades for political,international reasons and the driving force of civil society.Current FOI laws are greatly different in scope,exceptions,enforcement and ease of access.FOI laws have encountered many challenges.Facing the globalization of FOI laws,Researches have to be conducted in people's mentality,legislation and enforcement so as to promote the political and economical civilizations of China.


Thrombophilia in pregnancy is the result of a complex interaction of inherited and acquired factors, which increase blood coagulation and consequently placental ischemic conditions. Early identification of risk of developing thrombophilia in pregnancy is crucial for implementing preventive measures and personalized therapy. In this study, we propose a novel approach for prediction of thrombophilia in pregnancy utilizing machine learning (ML) algorithms with a particular focus on neural networks. The research is done using a dataset consisting of demographic, lifestyle, and clinical information from a 35 pregnant woman (22 healthy and 13 with thrombophilia). These features are used to train and evaluate different ML models with neural networks and decision trees. The evaluation of the proposed approach involves cross-validation and performance metrics assessment. The results highlight the effectiveness of decision trees and neural networks in accurately predicting thrombophilia in pregnancy risk.


Abstract The ratio, C, of the dynamical time-scale to the thermal time-scale of a star is small. This fact is used to develop an asymptotic theory of stellar pulsations, valid in the limit C → 0. The method is demonstrated in four planar models: a polytrope, a polytrope with an isothermal atmosphere, a layer containing a single ionization zone of finite thickness, and a layer in which there is an ionization front. In each case there is a thermal boundary layer associated with the oscillation. When it lies within the isothermal atmosphere of the second model, it is strongly destabilizing. If an ionization zone or front is to drive a layer towards instability, it must lie within the thermal boundary layer. The results for all four are compared with numerical work, and the agreement is shown to be qualitatively good. Only pulsations of infinitesimal amplitude are considered, except for the fourth model in which the so-called "saturation effect" is examined.


Abstract:Josh Mound presents a forward-looking analysis about the politics of achieving a single-payer Medicare-for-All program. He argues that the overall popularity of such a reform is not enough: Democrats must frame this policy in a way that speaks to the needs of their base, not the prerogatives of centrist wonks. The stakes are high: if they fail to do so, the whole endeavor could crumble.


(Top) An autonomous visual navigation scenario considered by the researchers, in a previously unknown, indoor environment with humans, using monocular RGB images (bottom right). To teach machines how to navigate indoor environments containing humans, the researchers created HumANav, a dataset that allows for photorealistic rendering in simulated environments (e.g. bottom left). Credit: Tolani et al.


The surface compositions of two types of stainless steels in vacuum were observed with AES and XPS at 1000–1100 K; a 304 stainless steel doped with nitrogen and boron (304‐NB) and a 304 stainless steel doped with nitrogen, boron, and cerium (304‐NBCe). The changes of surface compositions of these steels were compared with that of commercial 304 stainless steel. A thin layer of boron nitride came out from grain boundaries and spread over the surface of the 304‐NB, but did not uniformly cover the surface. The spreading mechanism of the boron nitride layer at the initial stage of heating can be explained by Avrami's model. In the case of 304‐NBCe, a boron nitride layer almost uniformly covered the surface at the early stage of heating, and rendered the surface inert to the adsorption of carbon and oxygen. Therefore, the 304‐NBCe stainless steel is a candidate material for vacuum vessels.


As the new method of machining, laser ablation has a lot of attractive advantages. The possibilities of dead end engraving and stable long term machining would be the great merits of micro-patterning to large metal mold which is used to the optical sheets for flat panel display for example. We developed pico-second laser machining system and manufactured micro-patterns on metal mold surface. And from those sample-machining results, we concluded it is possible to adapt this system to metal mold micro-pattern machining and decided to continue our development of laser machining.


A new resource allocation algorithm,which could ensure the fairness and meet the demand that multiple users transmit multiple traffics simultaneously in OFDMA mobile communication system,is proposed.The algorithm is mainly based on the cross-layer design.It takes into consideration both the QoS requirements of services in the MAC layer and the channel status information in the physical layer,hence makes adaptive resource scheduling to make a trade-off between the fairness and system capacity.Finally,the simulation results,show that the improved system has a higher capacity than the one not applying the traffic-diversity scheme.Besides,the proposed algorithm has an advantage on the performance of ensuing fairness compared with the one that based on the highest capacity.


This study aims to analyze the effect of tax planning and CSR (corporate social responsibility) on company value. This study also aims to analyze the role of moderation of the transparency of the influence of tax planning and CSR on the value of financial service companies listed on the Indonesia Stock Exchange in 2014-2018. The dependent variable is measured using Tobins' Q. Data is obtained by using the method of collecting documentation data obtained from data tracking through electronic media such as annual report data and company financial statements that are sampled. The total sample in this study were 40 companies determined by the purposive sampling method. Data processing techniques in this study use the method of multiple linear analysis and Moderated Regression Analysis (MRA) with SPSS Version 25. The results of this study indicate that tax planning and CSR affect the value of the company. In addition, this study also found that transparency can moderate the effect of tax planning and CSR on corporate value.


SUMMARY This paper is an overview of recently published research concerning the neuroleptic drug aripiprazole. Aripiprazole is an antipsychotic drug with high affinity for D2- and D3-receptors and the dopamine autoreceptor. It also has serotonin 5-HT1A-receptor partial agonist and 5-HT2A-receptor antagonist properties. It is prescribed in the treatment of schizophrenia and is under investigation for treatment of bipolar disorder. The drug is given by mouth in an initial dose of 10 or 15mg once daily. The dose may be adjusted at intervals of not less than 2 weeks up to a maximum of 30 mg daily. It appears to be useful in the treatment of schizophrenia and schizoaffective disorder and has a better side-effect profile than haloperidol.


This paper gives detailed introduction on the morphological character, life habit and utilized ways of Pachybeuron nawai, which has certain directive function for controlling this pest.


Food contamination caused by enteric pathogens is a major cause of diarrheal disease worldwide, resulting in high morbidity and mortality and significant economic losses. Bacteria are important agents of foodborne diseases, particularly diarrheagenic Escherichia coli. The present study assessed the genetic diversity and antimicrobial resistance of E. coli isolates from pasteurized milk processed in 21 dairies in northwestern State of Parana, Brazil. The 95 E. coli isolates were subjected to antimicrobial susceptibility testing according to the recommendations of the Clinical and Laboratory Standards Institute and assessed genotypically by Enterobacterial Repetitive Intergenic Consensus-Polymerase Chain Reaction (ERIC-PCR). The highest rate of resistance was observed for cephalothin (55.78%). ERIC-PCR revealed high genetic diversity, clustering the 95 bacterial isolates into 90 different genotypic patterns. These results showed a heterogeneous population of E. coli in milk samples produced in the northwestern region of Parana and the need for good manufacturing practices throughout the processing of pasteurized milk to reduce the risk of foodborne illnesses.


The intracellular distribution and quantitation of endogenously labeled iodine-containing compounds in normal rat liver, kidney and heart was determined under steady state conditions. An isotope equilibrium method based on chronic feeding of 125Ilabeled diet of known specific activity was employed. Virtually all of the label appeared as T4, T3 and iodide. T4 was more abundant than T3 in all fractions of liver, and in all fractions except nuclei of kidney and heart. T4 tended to concentrate in mitochondria, microsomes and soluble fraction and to be lowest in nuclei in all 3 tissues. This may be due to the available T4 binding sites in these fractions. T3 was more uniformly distributed among the 4 fractions. Quantities found per mg nitrogen were in the range of 0.1–0.7 mμg of T4 and 0.02–0.35 mμg of T3. Comparison of the subcellular distribution of endogenous hormone and exogenous hormone added in vitro to tissue homogenates indicated that the 2 methods of labeling gave different results. It would seem desi...


This reprint presents nearly coincident Chatanika radar electron-density measurements and NOAA 6 particle data for a continuous (diffuse) auroral E layer with a peak electron density of 100000 to 2001000/cc produced entirely by proton precipitation. The radar and particle data are analyzed using the Jasperse-Basu transport theoretic method and the semiempirical, continuous slowing down method of Rees. Comparisons between the radar results for the electron-density profile and the two theoretical results are given. It is concluded that the transport theoretic method of Jasperse and Basu gives a more-accurate result for the shape of the electron-density profile and for the location of its peak than the semi-empirical, continuous slowing-down method of Rees. The transport theoretic method is applied to derive a closed-form expression for the energy-deposition function, and the transport theoretic energy-deposition function is compared with that used by Rees in order to explain the differences in the electron-density profiles obtained by the two theoretical methods.


The aim of the study was to assess the oral health status and awareness of dental problem among young female adults. A total of 294 (147 teachers from Thingungyun Teacher's Training College and 147 factory workers from North Okkala and South Dagon Townships, Yangon Division) participated in the study in which data concerning oral hygiene and dental visit behavior, oral health status and awareness were measured. A descriptive, crosssectional, community-based, non-intervention type study design was used. Concerning oral hygiene behavior, most of them reported that brushing two times per day (82.3% of teachers and 78.2% of factory workers) and three minutes brushing (49.0% and 49.7%). However, they did not have knowledge of right time (56.5% of teachers and 76.9% of workers) and 6.1% and 43.5% reported they brushed horizontally. So, study population may have fair oral health knowledge. Regarding with awareness score, teachers scored two times higher than that of factory workers (6.51vs.3.76). No statistical differences were found between two groups relating to clinical data, mean DMF-T 0.91 vs. 1.27 , caries prevalence 35.4% vs. 44.2% and MNS for calculus 3.26 and 3.67 in teachers and factory workers respectively. There was significant relationship between oral health awareness and periodontal disease but not with dental caries. There was very weak negative correlation between awareness score and DMF-T was observed among the factory workers.


The corrosion and tarnish resistance of two Cu-Al alloys resembling commercial dental alloys of this type have been measured. Corrosion resistance has been found to depend upon chloride ion concentration rather than alloy type, whereas tarnish resistance appears to be a function of alloy composition.


Filtering and metering of traffic at highway bottlenecks influence delay and travel speeds along congested arterial streets. The current Highway Capacity Manual (HCM) method of analyzing urban arterial streets uses the filtering and metering adjustment factor I but does not give recommendations on how to adjust traffic volumes. An improved method of analyzing signalized arterial streets affected by bottlenecks is proposed. A set of equations has been derived to calculate the coefficient I and to adjust the traffic volumes. Conditions in which measured or predicted volumes should be adjusted and conditions in which they do not have to be adjusted are specified. The proposed method incorporates the effect of turning volumes, a feature not present in the current HCM method. A sensitivity analysis of travel speeds along an example signalized arterial street illustrates the filtering and metering effects and compares the results produced by the existing and proposed methods. The differences in the results are considerable. In addition, the significant effect of turning volumes has been confirmed. The proposed method tends to produce travel speeds higher than the values obtained with the current method, which concurs with comments from the users of the HCM that the current method underestimates travel speeds. The filtering equation has been derived with the assumptions of fixed capacity and no vehicle dispersion. Under the conditions violating these assumptions, the filtering equation may underestimate I. Further, the proposed method does not incorporate the effect of long queues blocking upstream lane groups. The negative effect on travel speed estimates along the entire arterial should be limited or negligible.


The following paper aims to contribute to the Italian literature on non-monogamy with a psychosocial interpretation towards the future of the political and legal recognition requests of non-monogamous and queer relationships, as well as of their families. Starting with a reflection on how normativities position those who are outside the binaries as noises to be ignored or cancelled, the paper then provides a critique of the concept of evaluation as a tool for acquiring rights (as it does not find a counterpart in the different-gender relationships). Psychosocial studies on the relationship quality of non-monogamous people should be used to strenghten the demands for the legal recognitions of non-monogamous relationships, families and multi-parenting. In fact, the available international literature has given voice and confirmed what the many polyfamilies experience in everyday life: that these families (non-monogamous, open, poly, extended, childless * or not) are a social reality with their positive charachteristics and criticalities. Starting from examples on the erasure of bisexualities and ame-gender families recognition – the paper discuss how including these types of psychosocial research can improve our struggle for the recognition and legal rights of non-monogamous agreements and relationships.


An analysis method for melt flow balance in plastics profile extrusion dies is presented. The method is based on a combination of cross-section method and flow path method. The method can predict average exit flow rate in multiple channel dies, i. e. dies provided with melt flow independent channels in the land and help designers evaluate and optimize die channel design. The methodolgy is very advantageous from a computational cost standpoint and suitable for engineering application.


Abstract In this paper, the boundedness and compactness of the generalized composition operators and the products of Volterra type operators a nd composition operators between QK spaces are investigated. We also give a necessary condition for multiplication operators between QK spaces to be bounded or compact.


The purpose of this work is measurement of the
system presampling MTF of a variable resolution x-ray (VRX) CT
scanner. In this paper, we used the parameters of an actual VRX CT
scanner for simulation and study of effect of different focal spot sizes
on system presampling MTF by Monte Carlo method (GATE
simulation software). Focal spot size of 0.6 mm limited the spatial
resolution of the system to 5.5 cy/mm at incident angles of below 17o
for cell#1. By focal spot size of 0.3 mm the spatial resolution
increased up to 11 cy/mm and the limiting effect of focal spot size
appeared at incident angles of below 9o. The focal spot size of 0.3
mm could improve the spatial resolution to some extent but because
of magnification non-uniformity, there is a 10 cy/mm difference
between spatial resolution of cell#1 and cell#256. The focal spot size
of 0.1 mm acted as an ideal point source for this system. The spatial
resolution increased to more than 35 cy/mm and at all incident angles
the spatial resolution was a function of incident angle. By the way
focal spot size of 0.1 mm minimized the effect of magnification nonuniformity.


A monitoring system of GaN growth process is introduced. Data acquisition modules, main temperature-controller and flowmeters are connected with standard RS-485 bus to compose the RS-485 network. Gas flow rates are set by the output voltage of D/A board. Vacuometers and assistant temperature-controller are connected with serial ports. Acquisition, displaying, controlling, setting, alarming, and printing of variables in the process are implemented in system program


We have successfully completed a proof-of-concept, one-year grant on a three-year proposal from the former NABIR program. Using a state-of-the-art 300-kV, atomic resolution, Field Emission Gun Transmission Electron Microscope (TEM), we have successfully identified three categories of mineral hosts for uranium in contaminated soils from the Oak Ridge FRC: (1) iron oxides: (2) mixed manganese-iron oxides; and (3) uranium phosphates.


Lithium niobate has been studied above its melting point by X-ray diffraction and Raman micro-spectroscopy. For two compositions (congruent and 54 mol% Li 2 O), a strange phenomenon occurs, starting approximately 10°C above melting: solid clusters (30 μm) appear in the liquid, remaining up to higher temperatures. These clusters are identified as ferroelectric lithium niobate by means of Raman and X-ray investigations.


⁎ Corresponding author. Fax: +1 613 562 5164. E-mail addresses: email@example.com (F. Ne 1 Doctoral Student at the J. Mack Robinson College o Management. 2 Fax: +1 404 413 7571. 3 Co-holder of the Deloitte Chair in the Managemen relate to SME growth, exporting and the role of gende 4 Fax: +1 613 562 5164. 5 Co-holder of the Deloitte Chair in the Managemen relate to the financing of smalland medium-sized en 6 Economist with the Small Business and Tourism Of medium-sized enterprises.


*† ‡ § This work is part of our ongoing research in the development and application of localized arc filament plasma actuators (LAFPA) to control high-speed and high Reynolds number jets for noise mitigation. The jet in the current work is an axisymmetric Mach 0.9 jet with a Reynolds number based on the nozzle exit diameter of 7.6x10 5 . We increased the number of actuators, distributed azimuthally inside the nozzle, near the nozzle exit, from 8 to 12, enabling us to excite higher azimuthal modes of the jet (m=0 to 5 and m=±1, ±2, ±3, and ±6) over a large frequency range (StDF of 0.1 to 5.0). Time-resolved pressure measurements, PIV measurements along with the Galilean decomposition of the velocity field, and far-field acoustic measurements were used to investigate the growth and decay of perturbations and instability waves in the flow, to visualize large-scale structures and the effects of control on the turbulence field, and to evaluate the control effects on the radiated noise field. Excitations with lower frequencies coupled to the flow, and the instability waves grew slowly, saturated farther downstream, stayed saturated for a longer time, and then gradually decayed, similar to the reported results in the literature using other techniques. The saturation and decay of instability waves moved upstream as the excitation frequency increased. Instability waves with higher azimuthal modes exhibited faster decay. Excitation of the jet around the jet preferred mode Strouhal number produced robust and coherent large-scale structures, similar to those in much lower speed and lower Reynolds number jets. The structures became smaller and less coherent in higher Strouhal number excitation. Far-field acoustic results show a significant noise increase when the jet is excited around the jet preferred mode Strouhal number (StDF=0.2-0.5), with larger increase from the shallower angle to the jet axis (30°) to the larger angle (90°), in agreement with the results in the literature. Noise reduction is observed over a large excitation frequency range - this reduction seems to peak around StDF =1.0 to 2.0 at 30°, but around StDF =3.0 to 3.5 at 90°. While forcing the jet with higher azimuthal modes (limited to m=0 to 5 in the current experiments, extended from m=0 to 3 in our previous work) is advantageous for noise mitigation at 30° and lower frequencies, the effect is not as clear in higher forcing frequencies and at 90°.


This paper deals with the topology optimized design of the riser support structures for floating production storage and offloading units (FPSOs) under global and local loading conditions. For a preliminary study and validation of the numerical approach, a simplified plate under static loading is first evaluated with the representative topology optimization methods, the Homogenization Design Method (HDM) and Density Method (DM) or Simple Isotropic Material with Penalization (SIMP). In the context of the corresponding riser support structures, the design problem is formulated such that structure shapes based on design domain variables are determined by minimizing the compliance subject to a mass target, considering the stress criterion. An initial design model is generated based on an actual FPSO riser support configuration. The topology optimization results present improved design performances under various loading conditions, while staying within the allowable limit of the offshore area.


Geometric magnetoresistance at the contacts of a Gunn effect oscillator can partly explain the decrease of the apparent threshold or current oscillations.


Dentistry clinic is a place where all people will attend once. A dentistry clinic is dominantly imagined as a frightening and stressful environment, this vision is resulted from existing clinics with no respect for architectural design and spaces merely for cure regardless designing factors. In current conditions, dentistry clinics are places lacking architectural identity and they do not meet patient's mental, sensory, emotional and curing needs perfectly. In this paper, role of architectural science and art in mental health promotion and healing process improvement and role of pleasant environment's constituent elements (compatible with human nature) are investigated. The objective of this research is to revision impact of architectural space on mental health and behavior and optimized design of interior architectural spaces and outdoor spaces in regard with lowering stress, increasing confidence, mental health promotion and improving patients' behavior. To achieve these objectives, data have been collected via library and documentaries research method and spatial solutions providing an appropriate environment in cure process have been proposed in order to design dentistry clinic. According to the results, it seems that architecture of environment, landscape and space's furniture (color, light, texture) can affect cure process promotion directly.


Abstract Background: Antibody-mediated extreme insulin resistance is characterized by hyperglycemia despite the use of >200 units of insulin/day and is often divided into two subtypes, insulin receptor antibody-mediated (Type B insulin resistance) and insulin antibody-mediated insulin resistance. The National Institutes of Health (NIH) published an immunomodulatory protocol for the treatment of Type B insulin resistance (1). However, there is scarce data on immunomodulatory therapy use for insulin antibody-mediated insulin resistance, and little has been documented to guide pretreatment screening. Clinical Case: We report the case of a 56 year-old Hispanic male with a 10-year history of well-controlled type 2 diabetes, who presented with abrupt onset hyperglycemia/diabetic ketoacidosis resistant to escalating doses of intravenous insulin infusion (>2500 units daily). He was diagnosed with antibody-mediated insulin resistance due to hyperglycemia requiring very high doses of insulin, lack of identifiable precipitants for diabetic ketoacidosis or hyperosmolar hyperglycemic state, and elevated insulin antibody levels. He underwent pre-immunomodulatory therapy screening for infections, rheumatologic disorders, and malignancy, which uncovered a new diagnosis of latent tuberculosis. He was started on treatment for latent tuberculosis, and began immunomodulatory therapy using the protocol developed by the NIH with rituximab, dexamethasone, and cyclophosphamide. One month after the second therapy cycle, insulin was no longer required for glycemic control, and he maintained appropriate glycemic control on oral diabetic agents alone (metformin and pioglitazone). Conclusion: This case validates the use of immunomodulatory therapy for the treatment of insulin antibody-mediated insulin resistance. It also highlights the importance of pre-immunomodulatory therapy screening to uncover occult infection prior to immunosuppression, and to investigate for possible causal neoplastic or rheumatologic disease. We propose an algorithm for pre-immunomodulatory screening prior to therapy in patients with antibody-mediated insulin resistance. Reference: (1) Malek R, Chong AY, Lupsa BC, et al. Treatment of Type B insulin resistance: a novel approach to reduce insulin receptor autoantibodies. The Journal of Clinical Endocrinology & Metabolism. 2010;95(8):3641-3647.


Due to their excellent mechanical properties and high specific mass, tungsten heavy alloys are used in demanding applications, such as kinetic penetrators, gyroscope rotors, or radiation shielding [1]. However, their composite structure, consisting of hard tungsten particles embedded in a soft matrix [2], makes the deformation processing a challenging task. This study focused on the characterization of deformation behaviour during thermomechanical processing of a W-Ni-Co tungsten heavy alloy (produced by powder metallurgy) via the method of rotary swaging (aimed at still improving properties) at ambient temper ature and at 900°C . Swaging changed mechanical properties, and - as an important step to optimize microstructure and mechanical properties is to understand the underlying processes - the aim of the neutron diffraction study was to determine texture and to characterize microstrain, dislocations as well as the active slip system. The strength of neutron diffraction method lies in the information provision from the bulk of the sample, i.e. not only from its near-surface region. This advantage is still amplified for materials with very high X-ray absorption (like tungsten alloys) and/or with large grains. phase identification detected phase corresponding to the original tungsten powder grains of bcc structure, the second (in fact matrix) phase, was Ni-Co solid solution with fcc structure Peak broadening after swaging visible in the soft matrix phase. measurement neutron diffraction


The Queen Mother of the West is an important legend figure in the ancient history and myths of China,people have discussed this question involved the prototype of the Queen Mother of the West all the time.This article,in the light of the limited documental data,makes a brief explanation on the folk phenomena reflected in the prototype and myth of the Queen Mother of the West starting from the semantic analysis and etymological pursuit.


Objective To study the efficacy and side effects of irinotecan on patients with metastatic and advanced esophageal cancer.Methods By searching Pubmed database and Wanfang database,multiple tests and clinical observations of irinotecan on metastatic and advanced esophageal cancer in recent years were summarized.Results The single use of irinotecan,irinotecan combined with chemotherapy,irinotecan combined with radiotherapy were both beneficial for patients with esophageal cancer,and the adverse effects were tolerable.Conclusions Irinotecan-based chemotherapy can be a new choice for patients with metastatic and advanced esophageal cancer.

Key words:
Esophageal cancer;  Irinotecan ;  Efficacy


13Gilbert GJ. The Medical Treatment of Spasmodic Torticollis. Arch Neurol 1972;27:503-6. 4Gowers WR. Manual of Diseases of the Nervous System. Darien, Connecticut: Hafner Publishing Co. 1893; vol. 11. lMatthews WB, Beasley P, Parry-Jones W, Garland G. Spasmodic torticollis: a combined clinical study. J Neurol Neurosurg Psychiatry 1978;41:485-92. 6Foltz EL, Knopp LM, Ward AA. Experimental spasmodic torticollis. J Neurosurg 1959; 16:55-67. 17Denny-Brown D. The mesencephalic and pretectal organisation. In: The Cerebral Control of Movement. Illnois: Charles C. Thomas, 1966; Ch. 6. 8Carpenter MB. A study of the red nucleus in the rhesus monkey. J Comp Neurol 1956; 105:195-249. 9Pycock CJ, Donaldson I, Mac G, Marsden CD. Circling behaviour produced by unilateral lesions in the region of the loceus coeruleus in rats. Brain Res 1975;97:317-29. 20Crossman AR, Sambrook MA. Experimental torticollis in the monkey produced by unilateral 6-hydroxydopamine brain lesions. Brain Res 1978;149:498-502.


The present proposal for work aims to understand, based on the configuration proposed by J. Ranciere's aesthetic unconscious of the Western tradition, the impact on the texture sensitive to the advent of man's interaction with the cybernetic machines. The Ranciere's reading of the history of Western, whose original structure is the inherited from the Christian exegesis of the reckoning hermeneutics of the other, will be the platform of understanding and integration of phenomenological descriptions of the processes associated to the news inscription process of meaning, inferring subsequently the conditions of possibility of the intellectual emancipation in the current cyber culture. This theoretical framework allows us to systematize the underlying processes of the formation of discursive corpus from which we will scrutinize the changes and fluctuations occurring in discursive tissue, the percetivas experiences that can be associated and, especially, the mentioned impact. PALAVRAS-CHAVE: inconsciente estetico; subjetividade; sentido e emancipacao


An laser-diode (LD) end-pumped Nd-doped Yttrium Vanadate (Nd:YVO4) laser was demonstrated to emit the first order Laguerre-Gaussian (LG01) mode. This LG01-mode laser is compact and efficient.


We read the paper by Li and co-workers (Li et al., 2023) with interest as it addresses the important question of how breathing is controlled by brainstem mechanisms to ensure effective elimination of metabolically produced CO2. The authors focused on the interactions between chemosensitive neurons and glial cells in the retrotrapezoid nucleus (RTN) and their role in central respiratory CO2 chemosensitivity (Gourine & Dale, 2022; Guyenet et al., 2019). In this article, the authors described the results of experimental animal studies designed to determine the role of the electrogenic Na+-HCO3− cotransporter NBCe1 (Slc4a4), expressed by RTN astrocytes, in mediating the effect of CO2 on breathing. The authors crossed Slc4a4fl/fl mice with astrocyte-specific cre recombinase-expressing mouse lines: GFAP-cre or Aldh1l1-Cre/ERT2, with the aim to delete NBCe1 in astrocytes and determine the ventilatory responses of these animals to increasing levels of inspired CO2 (hypercapnia). The authors found that the responses to hypercapnia were similar in cre-negative and cre-positive GFAP-Cre;Slc4a4fl/fl mice and Aldh1l1-Cre/ERT2;Slc4a4fl/fl mice and concluded that NBCe1 is dispensable for central respiratory CO2 chemosensitivity, as emphasized in the title of this work (we noted that the original title of the paper first published online, 'The astrocytic Na+-HCO3− exchanger NBCe1 is dispensable for respiratory chemosensitivity', had been corrected by the authors in response to this letter). It could be argued that such definitive conclusions can only be made based on compelling experimental evidence. In the case of this study, the conclusions reached by the authors would require clear evidence that the genetic manipulations performed led to amarked reduction of NBCe1 protein expression and loss of NBCe1 function in brainstem astrocytes. The data presented show a substantial, yet partial, reduction of NBCe1 expression with significant NBCe1 mRNA levels remaining in the RTN of cre-positive GFAP-Cre;Slc4a4fl/fl mice (Fig. 1G). Therefore, the terms used by the authors, such as 'NBCe1 knockout mice', 'deletion of Slc4a4', 'elimination of NBCe1 from GFAP-expressing astrocytes', are not entirely accurate or appropriate. Such terms typically imply a complete or near-complete removal of the gene or its functional product, while in the animal models used in this study, the deletion of NBCe1 was clearly incomplete. The authors stated that they 'obtained a more widespread deletion of NBCe1 in brainstem astrocytes by using tamoxifen-treated Aldh1l1-Cre/ERT2;Slc4a4fl/fl mice'; however, only individual RNAscope images of the brainstem are shown (Fig. 5), and no quantitative data and no NBCe1 protein expression data are reported that would allow the reader to evaluate the effectiveness of this genetic approach. The authors performed electrophysiological recordings from astrocytes in brain slices and documented robust outward currents upon exchanging the perfusate from a HEPES-based to a CO2/HCO3−-buffered solution (Fig. 1J and K). The raw data presented (Fig. 1J) actually show significant electrogenic Na+-HCO3− transport in astrocytes of cre-positive GFAP-Cre;Slc4a4fl/fl mice. The illustrated effect of S0859 in astrocytes of control mice is not convincing since (at least in this particular example) the drug was applied at exactly the time point of the response to CO2/HCO3− when NBCe1 current normally declines to a lower level (compare with Fig. 2C in Brune et al., 1994). The data reporting CO2-induced currents and depolarisations in astrocytes of cre-negative and cre-positive GFAP-Cre;Slc4a4fl/fl mice (Fig. 4B and C) are not very informative because NBCe1 function cannot be reliably assessed in the electrophysiological experiments of this type. Since NBCe1 is critical for pHi homeostasis in astrocytes (Chesler, 2003; Theparambil et al., 2014), evidence of impaired pHi regulation would be required to demonstrate the loss of NBCe1 function in these cells. In summary, the data reported by Li and colleagues (Li et al., 2023) did not provide definitive evidence that genetic manipulations, involving crosses of Slc4a4fl/fl mice with GFAP-cre or Aldh1l1-Cre/ERT2 mice (followed by treatment with tamoxifen), resulted in a significant reduction of NBCe1 protein expression and loss of function in brainstem astrocytes. Therefore, in our opinion, the conclusions reached by the authors of this paper cannot be made based on the reported data. A recent study by Brady et al. (2023) evaluated the respiratory responses to metabolic acidosis in mice with genetic deletion of NBCe1 variants B and C. The readers of this paper learn that NBCe1 has three variants NBCe1-A, -B, and -C. NBCe1-A and NBCe1-B are expressed in the kidney (where NBCe1-A plays an important role in the reabsorption of bicarbonate); while NBCe1-B and -C variants are expressed in the brain. The authors described thorough validation of NBCe1-B/C specific antibody and demonstrated deletion of NBCe1-B/C protein in the brainstem (including the RTN) of NBCe1-B/C knockout mice. The authors reported disturbed respiratory homeostasis (higher resting ventilation) and impaired respiratory responses to metabolic acidosis (also associated with more severe acute decreases in plasma pH) in this animal model. Although the authors of this study did not test the ventilatory responses to CO2, the data obtained allowed them to conclude that under conditions of NBCe1-B/C deletion in the brain, the "integrated response (tometabolic acidosis) is disturbed such that the burden of work (to remove CO2/H+) shifts from the respiratory system to the kidneys". In stark contrast to the conclusions reached by Li and colleagues (Li et al., 2023), this would imply that NBCe1 activity is critically important for the operation of the brain mechanisms that mediate the effects of CO2/H+ on breathing.


The average anxiety experienced by third-trimester pregnant women is higher than the first and second trimester. Anxiety increases as the gestational age get older. If this condition had not to handle, it could impact on pregnancy and during labour. Efforts to overcome anxiety can be made with music therapy. This therapy is therapy without drugs by playing music to pregnant women. Song rhythm, harmony, and beat 60 beats per minute can make the mother calm. The purpose of this study was to determine the level of anxiety of pregnant women before and after the intervention, then analyze the effectiveness of music therapy in reducing anxiety levels. The method used is a quasi-experiment. The population in this study was third-trimester pregnant women in the Ambarawa Puskesmas area with samples taken by purposive sampling of 30 respondents. Data collection carried out in August 2019. The data not normally distributed, so the analysis carried out using the Wilcoxon test with the results that there were different levels of anxiety before and after treatment with music therapy (p = 0.001). The average anxiety score after being given music therapy dropped to 4.47 from 9.53, although it was still in the mild anxiety category. It can be concluded that music therapy is effective in reducing the anxiety level of pregnant women in the third trimester. Music therapy recommended being applied in the management of anxiety on pregnant women in the third trimester. Key Words : Anxiety Level, Music Therapy, Third-trimester, Pregnant Women


To enhance the capability of independent innovation is the major means and the ultimate method to carry out the scientific view of development and to achieve the change in the pattern of economic growth.In recent years,economy has been keeping rapid growth in Shandong.At the same time,there still exist inadequate investment in science and technological output structure and the low contribution rate of technology advance.So,we must realize the transformation of the mode of economic growth and the favorable and fast development of economy in Shandong through enhancing the capability of independent innovation.


The main objectives of the study was to determine the strategies for improving acquisition of maintenance skills in
Agricultural Equipment and Implement Mechanics work trade in technical colleges in EnuguState. The study guided by
three research questions in line with the purpose of the study. Three null hypotheses were formulated and tested at 0.05
level of significant. The study adopted a descriptive survey research design. The population for the study was 69, which
comprised four school administrators, ten trade teachers and 55 final year students of eight accredited government
technical colleges in EnuguState. There was no stapling due to the manageable size of the population. The instrument for
the data collection was a 28 item questionnaire developed by the researcher after an extensive literature review. The
instrument was structured in five point rating scale and was facevalidated by three experts. The reliability of the
instrument was determined using Cronbach Alpha and the internal consistency yielded 0.87 index coefficient. Mean with
standard deviation was used to answer the research questions based on the data collected from the study, while t-test
analysis was used to test the null hypotheses at 0.05 level of significance. Based on the data collected, findings and
recommendations were made among which were; that teachers of Agric equipment & implements mechanics work trade
in technical colleges should encourage practical exercise to develop skills into the learners, Agric equipment &
implements mechanics work trade teachers should adopt the strategies based on the findings of this study to enhance
teaching practical maintenance skills in technical Colleges; Agric equipment & implements mechanics work trade
teachers should encourage project method of teaching and guided practice to promote active learning of needed skills
and school administratos partnership with resource persons outside the school environment.


Stringing haulage motors were main underground conveyance equipments, but they were the strong electromagnetic interference sources. To resolve the problem of monitor system false alarm and mobile communication interruption, the interference generation mechanism and distribution characteristic were analyzed. The means of conducted interference circuit analysis and stray current quantitative analysis were adopted. A novel field way was put forward in which the radiated emission measurement in the coal mining roadway was accomplished. The data was acquired through the R&S spectrum analyzer FSP7. The conducted interference, stray current and radiated interference were the main factors of monitor and mobile communication malfunction. The anti-interference measures were taken, which included the power supply isolation, earth, the improved complex EMI filter and shield to radiated interference. Results indicate monitor system false alarm and mobile communication interruption have been eliminated completely. It is concluded that the electromagnetic compatibility of underground monitoring and mobile communication systems have been enhanced evidently with these anti-interference measures.


the nutritional the was in�uenced method of had adequate nutritional pro�les, amino nucleotides. susceptible to degradation. Study describes development and evaluation of an "all-in-one" stacked system for indoor production of black soldier fly larvae.


ABSTRACT Two case studies of the herring industry reveal that insufficient data on processes and traceability are currently recorded onboard fishing vessels, at primary processing into marinated herring fillets and at secondary processing into small jars as pickled herring products. This means that the traceable unit of a batch of herring is at the level of a whole fishing trip, and that there is a disconnection in traceability along the chain. Data on process and product parameters are insufficient and precludes the use of modern data analysis to examine where improvements and greater efficiencies can be obtained. Suggestions and procedures to overcome these deficiencies are outlined and discussed.


Purpose. To optimize the scope of preoperative diagnostics in patients with persistent fetal vascular network. Material and methods. The Kaluga branch underwent surgical treatment of 30 patients with various manifestations of persistent fetal vascular network from 2015 to 2020. The age of the patients was from 3 months to 8.5 years. At the stage of preoperative diagnostics, additional research methods was used: fluorescence angiography (FAG), ultrasound color duplex scanning (UCDS), ultrasound biomicroscopy (UBM). Results. A complex of diagnostic measures made it possible to develop the most individualized plan for surgical treatment. In 16 patients, the anterior type of the disease was determined – phacoaspiration with IOL implantation was performed according to the standard technique, if necessary, a "dry vitrectomy" was carried out with the removal of the posterior lens capsule and adjacent parts of the vitreous body. In 11 patients (11 eyes) with a mixed type, phacoaspiration of the lens with IOL implantation and simultaneous 3-port 27g vitrectomy was performed according to the standard technique; tamponade of the vitreous cavity was not carried out. In 10 patients (30%) in the period from 6 months to 1.5 years after the first intervention the reoperation was required. In 27 patients (90%), the transparency of the optical surroundings was restored. Complete retinal attachment was observed in 22 patients (73%). For 3 to 6 months after surgery in 5 patients (17%), traction retinal attachment occurred. In 3 patients (10%), retinal attachment was not achieved despite repeated interventions. Conclusion. A differential approach to each patient based on preoperative multimodal diagnosis made it possible to expand the indications for surgical treatment and achieve satisfactory anatomical and functional results. Keywords: persistent vascular fetal network, complex of preoperative diagnostics, fluorescent angiography, ultrasound color duplex scanning, ultrasound biomicroscopy.


Ten storied -3bays reinforced concrete bare frame designed for gravity loads as per IS 456: 2000 (rev) and IS 13920: 1993 for ductility is subjected to seismic loads. Seismic loads considered is earthquake loads determined from IS 1893-2002 (part 1) response spectra for 5% damping (for hard soil). Structural elements are modeled as two node element (three degrees of freedom at each end). Plastic hinges are used to represent the failure mode in the beams and columns when member yields. Pushover analysis is performed using SAP 2000 V 14.0 commercial software in reference to various performance levels suggested in first, second and next generation performance based design procedures (ATC 40, FEMA 356, FEMA 440). Base shear versus top displacement curve of structure, known as pushover curve is obtained for force-displacement (brittle) and Deformation-controlled (ductile) actions of plastic hinge. Lateral deformation at performance point proves the building capability to sustain certain level of seismic loads. The failure mechanism indicates structural performance levels in accordance first, second and next generation PBSD procedures. The study aims towards understanding the first, second and next generation PBSD evaluation procedures.


This thesis expatiates upon the content and influence of the traditional image of the officer, gentry and peasant, which was set for morally cultivating the masses and maintaining the ruling order of the society. This image had made a significant impact on people in every area of modern rural community before the communist revolution, and closely related to the initial mode and practical measures of the revolutions during the Anti—Japanese War and distinctively affected the Land Revolution as well.


In many national histories, certain features become distinct signifiers of cultural authenticity within that country's traditions. In current academic, political and popular discourses on Vietnam, 'Woman' emerges as the embodiment of Vietnamese tradition and as a key signifier of that country's readiness for modernity.1 The Vietnam Women's Union, the key state institution charged with implementing gender equity laws in the Socialist Republic of Vietnam, proclaims that Vietnamese women 'preserve [Vietnamese] uniqueness and play an important role in the development of identity and cultural genius of its people (giữ gı̀n phát triển bản sắc tinh hoa văn hoá dân tộc)'.2 As the embodiment of Vietnamese tradition, 'Woman' is represented in the scholarly and popular imaginations in three reified forms: a sign of Confucian oppression, of Vietnamese uniqueness or of Southeast Asian cohesiveness. At the heart of these representations is the notion that Vietnamese women's historical social status signals the country's readiness for modernity.3 In this article, I argue that these models of Vietnamese womanhood, born out of French colonial efforts to define Vietnamese authenticity and re-articulated by Vietnamese political actors and scholars to represent national uniqueness, have been central to the formation of the modern Vietnamese nation state. In the twentieth century, French colonial scholars and their Vietnamese counterparts deployed the image of the 'traditional' Vietnamese woman as an important measure of the 'cultural distance' between Vietnam and the West, a practice that Westerners have long used to mark the stage of modernity for the colonised world.4 In the postcolonial era, these discourses have lingering effects on the lives of contemporary Vietnamese women, whose economic and political futures are tied to national and international representations of their experiences. When represented as the embodiment of Confucian oppression, Vietnamese women and their historical social position characterised all that was wrong with local culture – Chinese influence, patriarchal rule and Vietnamese backwardness. In this context, only the establishment of Western-style modernity in terms of secularity, individualism and democracy could free Vietnamese women from the shackles of tradition. French colonial officials charged with implementing the civilising mission, Vietnamese nationalists advocating the adoption of Western institutions and international development organisations hoping to emancipate Vietnamese women from their traditional roles have collectively produced and perpetuated this model of Vietnamese


Objective To explore the effects of inhibiting the expression of LRIG3 gene on prolif-eration and apoptosis of human glioma cell line GL15 and explore its possible mechanism by using small interfering RNA (siRNA) targeting LRIG3 gene.Methods Two pairs of pGenesil2-LRIG3-shRNA (siR-NA) were transfected into GL15 glioma cells by Metafectine as experimental groups 1 and 2,and the cells that had a stably suppressive LRIG3 expression were selected by G418.The control ceils were transfected with negative shRNA.The changes in LRIG3 mRNA and protein levels were measured by RT-PCR and Western blot.The apoptosis rate and cell cycle were analyzed by flow cytometry.Results Compared with LRIG3 mRNA expression in the negative shRNA-treated GL15 cells, the transcription after treatment with LRIG3-specific shRNA was silenced by 52.4% and 63.8%,and the expression of LRIG3 protein was re-duced by about 50.9% and 67.4% in experimental groups 1 and 2 respectively.Cell cycle analysis showed that silencing LRIG3 increased the percentage of G2/M phase cells and improved the proliferation index significantly (P<0.01).Conclusion The siRNA targeting LRIG3 gene can dramatically inhibit RNA transcription and protein expression, then promote the proliferation of GL15 ceils and suppress the apoptosis of GL15 cells.

Key words:
Glioma;  RNA interfering;  Cell cycle;  Apoptosis


Aspects of channel morphology were examined across the stream network in the Kangaroo River catchment, NSW. Downstream hydraulic geometry relationships were analysed as appropriate methods of predicting alterations in channel morphology with increasing scale within a network context. Examining river network behaviour in this way enhances understanding of the way in which geomorphic processes behave across networks. This in turn provides scientific grounding for stream management on a network scale. A similarity between downstream and network hydraulic geometry relations was found, suggesting the potential for modelling adjustment in channel form to discharge regimes across the network. The potential for the use of network hydraulic geometry relationships in assessments of river channel condition is discussed.


Food is one of the best media for the microorganism to live and grow. Therefore, food is often broken because it has been contaminated by the microorganism. In industry country, approximately 30% of population infected by food borne disease. Food borne disease is caused of phatogen bacteria food borne. Staphylococus aureus is a kind of bacteria that can make food rotten and also it is a phatogen bacteria cause food born disease, no forming spora, positive gram bacteria and the food substance which is contaminated by Staphylococus aureus will cause poisoned becaused of enterotoxin which is heat resisting. Essential oil is antimicrobial and anti bacterial that the most effective, it can inhibit the growing of microba and bacteria. One of the example of essential oil is Cinnamon.sp oil. Cinnamon oil is antimcroba agent for bacteri and fungi because it contain cynammyldehyde and cynammyl alcohol and also eugenol. The aim of this study is to understand the antimcrobacterial potential of cynammyldehyde from cinnamon extract to Staphylococus aureus. This study is laboratory experimantal research. Essential oil from Cinnamon by destilation, then redistilation was done to get cynammyldehyde from cinnamon. Cynammyldehyde was tested to Staphylococus aureus. Test method was done as dilution in the form. From this result, it show that cynammyldehide from cinnamon extract has ability in inhibit the Staphylococus aureus growth. We can conclude that Cynammaldehyde from cinnamon extract has antibacterial effect especially for positive gram bacteria that is Staphylococcus aureus. The optimum inhibiting effort is 0.09%.


The first observation of the semileptonic b -baryon decay Λ 0 b → Λ þ c τ − ¯ ν τ , with a significance of 6 . 1 σ , is reported using a data sample corresponding to 3 fb − 1 of integrated luminosity, collected by the LHCb experiment at center-of-mass energies of 7 and 8 TeV at the LHC. The τ − lepton is reconstructed in the hadronic decay to three charged pions. The ratio K ¼ B ð Λ 0 b → Λ þ c τ − ¯ ν τ Þ = B ð Λ 0 b → Λ þ c π − π þ π − Þ is measured to be 2 . 46 (cid:2) 0 . 27 (cid:2) 0 . 40 , where the first uncertainty is statistical and the second systematic. The branching fraction B ð Λ 0 b → Λ þ c τ − ¯ ν τ Þ ¼ ð 1 . 50 (cid:2) 0 . 16 (cid:2) 0 . 25 (cid:2) 0 . 23 Þ % is obtained, where the third uncertainty is from the external branching fraction of the normalization channel Λ 0 b → Λ þ c π − π þ π − . The ratio of semileptonic branching fractions R ð Λ þ c Þ ≡ B ð Λ 0 b → Λ þ c τ − ¯ ν τ Þ = B ð Λ 0 b → Λ þ c μ − ¯ ν μ Þ is derived to be 0 . 242 (cid:2) 0 . 026 (cid:2) 0 . 040 (cid:2) 0 . 059 , where the external branching fraction uncertainty from the channel Λ 0 b → Λ þ c μ − ¯ ν μ contributes to the last term. This result is in agreement with the standard model prediction.


In recent years, based on maturity of AGC technology, the accuracy of Thickness Control has been improved greatly. The poor profile control is the major factor which restricts the dimensional accuracy. The mathematical model of plate shape-setup is the basis for realizing the process control of strip mill. Because the deviation of the mathematical model, the device and the parameter is inevitable during actual rolling, self-learning is an important mean to reduce the error of the set-up model. On a production line, the self-learning algorithm is not in line with actual production, which results in control chaos. To solve this problem, combined with the actual production process, a new self-learning algorithm has been developed, which considers operator revision, unstable error interference and actual parameters optimization. New algorithms has been applied, it has solved the phenomenon of self-learning disorder, improved the hit rate of profile greatly, and improved the quality of the production.


ABSTRACT This article explores explicit and implicit dimensions of identity that Negev Bedouin students position in their life stories. The literature review probes the participants' historical, cultural and social contexts and presents the critical discourse-oriented perspective adopted in the study to explore identity construction in narrative discourse. Fourteen men and 16 women attending a college of education in southern Israel were asked to write meaningful stories related to various chapters in their lives. Interpretation of explicit themes and silences show that women and men positioned themselves as two separate groups vis-à-vis the male-dominated Bedouin tradition, and the Israeli government.


The interactive multimedia service is expected to be a cornerstone of success in deploying the ATM-based access transport network. A hybrid access network architecture, which is combined with ring topology for the special community such as government and double star topology for the residential subscribers, would satisfy both service requirements of interactive multimedia-on-demand and economic opportunities of an access transport network. The adoption of different topology according to subscriber segments in one access network system results from user's requirements with different network reliability and evolutionary path. Because each subscriber segment needs different traffic class in different busy hour, the utilization of the common switching platform named as head node would be maximized. The cost evaluation is performed on five alternatives of access transport network based on the sum of cabling and network node cost. The result of evaluation is that only for an economic solution the double star is recommended for both the special community and the residential, while with consideration of serveability a hybrid with double star would be the optimized choice.


This paper presents a brief introduction of the properties of the clothes of the Song Dynasty by analyzing the historical and cultural background during the period. It highlights the relation between the most representative clothes of Song Dynasty, namely the clothes of senior officials and scholars, and its particular cultural background such as the rationalistic Confucian philosophy, Chan sect, poetry as well as the mountains-and-waters (Chinese traditiona1) painting, thus drawing the conclusion that clothes are an important carrier of culture.


The conduct of the electrical networks has known in recent year's major changes induced mainly by the technological development of power electronics as well as the information systems and communication (Smart Grid), added to this is the integration of intermittent sources of production and competitive requirements advocating the power quality and the continuity of service as major objectives. That said it is understood that the electrical networks serve a set of vulnerabilities due to the intrinsic parameters including the'' topology'' of the network which requires the distribution of power that can migrate to unstable states face particular hazards. Before foregoing the present work is a participation in the development of a new concept of regulation of power systems based on the control of the topology provided to develop the network stability by a new field control which is not supported in patterns regulatory body.


Early in 1963 Oudin observed that the injection of Salmonella typhi and its homologous antibody, produced in one rabbit, elicited in other rabbits with the same allotypic specificities the production of a special type of antibody. It was shown that these antibodies were directed against the idiotypic determinants of the anti-Salmonella antibodies. Idiotypic determinants are specific for antibodies directed against a given antigen synthesized by an individual or a group of individuals (Oudin 1966). Later, it was demonstrated that idiotypic detenninants were located on the variable regions of immunoglobulin molecules (Solomon & McLaughlin 1969, Wells et al. 1973).


Some components of the photometric equipment, designed and made for the high speed multichannel stellar photometry for the Whole Earth Telescope (WET) program and other astronomical programs, are described. Despite of a special destination, the described equipment could be also used for any kind of stellar photometry, especially for observations of variable stars. Small size and weight of the equipment makes it suitable for observations in expeditional conditions. An original solution of the step-motor feeding for the the filter wheel rotation is presented, and the filter setting system FD 306 based on it is described and discussed.


Semantic segmentation works on the computer vision algorithm for assigning each pixel of an image into a class. The task of semantic segmentation should be performed with both accuracy and efficiency. Most of the existing deep FCNs yield to heavy computations and these networks are very power hungry, unsuitable for real-time applications on portable devices. This project analyzes current semantic segmentation models to explore the feasibility of applying these models for emergency response during catastrophic events. We compare the performance of real-time semantic segmentation models with non-real-time counterparts constrained by aerial images under oppositional settings. Furthermore, we train several models on the Flood-Net dataset, containing UAV images captured after Hurricane Harvey, and benchmark their execution on special classes such as flooded buildings vs. non-flooded buildings or flooded roads vs. non-flooded roads. In this project, we developed a real-time UNet based model and deployed that network on Jetson AGX Xavier module.


In the quiet lodgings where the great aunt livesEverything recalls the bygone days of olden times,The courtyard with its sonorous wells, the old servant,And the century-old tarnished mirrors…Willia...


CTLA‐4 is a T cell surface receptor essential for the negative regulation of T cell activation. In the CTLA‐4‐deficient mouse, a dramatic accumulation of activated peripheral T cells effects extensive damage to host tissues, resulting in mortality within 5 weeks of age. To determine whether the accumulation of activated T cells in CTLA‐4−/− mice is due to a defect in thymic selection, we examined negative selection in CTLA‐4−/− mice using two transgenic T cell receptor (TCR) models of thymic selection. Neither the H‐Y‐specific TCR nor the lymphocytic choriomeningitis virus (LCMV)‐specific TCR transgenic models revealed a defect in positive or negative selection in CTLA‐4−/− mice in vivo or in vitro. In fact, the negatively selecting phenotype of male H‐YTCR‐transgenic mice greatly mitigated the accumulation of activated peripheral T cells. Further, peripheral CTLA‐4−/− T cells expressing a single LMCV‐specific transgenic TCR did not have an activated phenotype, indicating that CTLA‐4−/− T cells require specific antigen for proliferation. These results demonstrate that specific antigen is required for the lymphoproliferation observed in CTLA‐4−/− mice, and that CTLA‐4 deficiency does not lead to a gross defect in negative selection.


Orthogonal Frequency Division Multiplexing (OFDM) is widely recognized key challenge for the next generation Broadband Wireless Communication (BWC) systems. Besides high spectral efficiency, reliable performance over fading channel and long delay is becoming more and more important for OFDM based BWC systems. The time domain synchronous OFDM (TDS-OFDM) has high spectral efficiency than the standard cyclic prefix (CP-OFDM) but suffers from severe performance over high speed mobile channel since the required iterative interference cancellation between the training sequence and the OFDM data block. In this paper a distinct OFDM based transmission scheme called Time Frequency Training OFDM (TFT-OFDM) is proposed, whereby every TFTOFDM symbol has training information both in time and frequency domain. Firstly, exploiting the signal of proposed TFT-OFDM scheme the auxiliary channel information is obtained. Secondly we propose the auxiliary information based subspace pursuit algorithm to use a small amount of frequency domain pilots in the OFDM block for exact channel estimation. Simulation results also demonstrate that TFT -OFDM outperforms CP-OFDM and TDS-OFDM in high speed mobile environment and supports higher order modulations like 256-QAM to accommodate the emerging ultra-high definition television service.


Recent research in lifespan development has shown that young adults are able to make projections as to their anticipated status later in life. The current investigation invited undergraduates to assess themselves and peers now, and at the ages of 65 and 85 years of age. These ratings were taken together with ratings of the typical person at those latter ages across two communicative (viz., accommodation and nonaccommodation) and personality (viz., personal vitality and benevolence) dimensions. Given that varying conceptions of the self have been documented cross‐culturally, the study was conducted in both the USA and Japan. The results showed respondents projected that their language and personality make‐ups would change later in life and that the emerging patterns would be very different across the four dependent measures. As predicted, Japanese respondents showed less differentiation across the social targets rated than did their American counterparts. The social significance of these findings is discussed along with avenues for further research.


Under the requirement of economic globalization and construction,academe pays more attention to the Constitution theory in international economic law.The theory basis of constitution existed much localization in international economic law.We should admit its active means.However,we have to realize its shortage and faced with the difficulties in institution construction.


Abstract Phosphate ion is an essential nutrient for all cells. Consequently, starvation for this component may constitute a stressing condition which affects the bioleaching capacity of the biomining microorganisms. Therefore, we have studied the manner in which the chemolithotroph Thiobacillus ferrooxidans responds to phosphate limitation. Under these circumstances the bacteria reduced its growth rate, capacity to oxidize ferrous iron and to fix CO,. Concomitant with these changes, the cells showed an increased synthesis of several proteins, some of which were exclusively synthesized during phosphate starvation. When intact cells grown in the absence of phosphate were labelled with 125 I, several proteins were iodinated in addition of those observed in control cells, suggesting that the lack of phosphate induces some proteins located in the membranes or the periplasmic space of the bacteria. It is expected that by measuring the levels of expression of some of the proteins induced by the shortage of phosphorus, it might be possible to estimate in situ the relative physiological condition of the bacteria in a given bioleaching operation.


The purpose of this study was to examine whether second-year Master of Occupational Therapy (MOT) students who enroll in the elective course "Occupation in Long-Term Care (LTC)" would be able to apply concepts of occupational justice in the nursing home environment through engaging residents in occupational storytelling and story making in order to facilitate resident self-advocacy for participation in a valued occupation. The occupational therapy elective course was developed and implemented with students alternating between the classroom and the nursing home environments. Outcome evaluation measurements included analysis of student reflective journaling to obtain qualitative data. The researcher found that students are able to understand the concepts and issues of occupational justice in the nursing home population and apply knowledge to facilitate the resident's participation in meaningful occupations.


Channel reconfiguration to mitigate a variety of riverine conditions has become an important issue in the western United States. Reasons cited for channel reconfiguration include restoration to more natural or historical conditions, improved water conveyance in flood-prone areas, mitigation of unstable streambed and streambanks, more efficient sediment transport, and enhancement of fish and riparian habitat. Numerous projects have been undertaken to reconfigure stream and river channels. However, the effectiveness of these modifications over a period of time, in terms of channel changes and achievement of project objectives, has not been assessed in a consistent manner.


Diatomite has unique micropore structure,large specific surface area,huge porosity,and surface was covered with a large number of silicon hydroxy,it also contained iron oxide,aluminum oxide and and other components. That made it possible for the preparation of efficient and multifunctional coagulant. The preparation methods of composite diatomite coagulant and the factors in the process of coagulation were elaborated in this paper. It could be used in the removal of high concentration of organic matter,heavy metal ion,algae in water and used in sludge dewatering etc.,which were difficult for conventional coagulants. This paper provided basic information and ideas for the related research.


As the economic reform goes into deeper recently, the conditions both in subjective and objective of operating intermediary service in commercial banks in our country have changed in several aspects. The changed conditions are as following: such as controlling to the excessive investment; the speeding up the process of interest rate market orienting; strengthening the financial lows and regulations; business segregation slowly transiting to universal banking; the self reformation going deeper of commercial banks and the increasing in income level of ordinary people and etc. Those changes gradually become advantages of developing intermediary service by commercial bank. Through multi visual angle and all-round analyzing reality condition, it is possible to provide foundation for commercial banks formulating practical policy of developing intermediary service.


Knudsen evaporation experiments were made on gadolinium sesquioxide from 2350° to 2590°K. Two sets of Knudsen cell data yielded average values of 468.7 ± 0.8 and 471.0 ± 0.5 kcal/mole for the assumed evaporation reaction

The results indicate that the evaporation coefficient may be much less than one.


Pellet fueling and impurity transport have been investigated in high poloidal-beta (βp) and reversed shear (RS) plasmas. It is observed that pellet injection from the high-field side at the top is more effective for density increase in the neutral-beam-heated plasma compared with pellet injection from the low-field-side midplane. This observation is consistent with the radial displacement theoretically predicted based on the E×B drift model, where deeper deposition is suggested for the high-field-side pellet injection. Using the high-field-side top pellets, the accessible density region of the high βp plasmas is extended to 70% of the Greenwald density with a confinement enhancement factor over the ITER89P scaling of 1.94, a normalized beta of 2.2, and a bootstrap current fraction of 60%. The impurity diffusivity at the internal transport barrier is only higher by a factor of 2–4 than the neoclassical prediction in the RS plasma. In contrast, the impurity diffusivity is two orders of magnitude higher than...


The unsteady hydrodynamic forces acting on a berthing ship model was examined, and an procedure for the analysis of measured result in towing tank was considered. The blockage effect could be a problem if we execute the large attack angle lateral force measurement in towing tank, and it will be much serious in the case of shallow water. The authors proposed an experimental procedure, which enables us to carry out the test in towing tank. The proposal employ the normal size model ship with the resistance test, and the blockage effect was avoided by towing the model normal to the tank length. The additional problems in connection with the side wall of towing tank was considered as well. The refected waves affect on the measurement, and it causes unstediness. The authors consider the analysis process on that factor, and they proposed practical solution to extract steady component.


Abstract : The major themes of the research supported under this grant are the discrepancy between normative and descriptive theory and the constructive nature of decision and judgement. In contrast to the classical theory that treats preferences as given and describes choice as a maximization process, the present approach holds that preferences and judgements are often constructed in the elicitation process. Furthermore, these constructions are contingent on the framing of the problem, the method of elicitation, and the context of choice. During the last three years, we have made considerable progress towards the development of a constructive analysis of choice, documented in the enclosed articles. The present report reviews the major themes: (1) Resolving Conflict; (2) Reference-dependent Theory; (3) The Aggregate/Individual Discrepancy; (4) Elicitation Effects and the Compatibility Principle; (5) Preference and Belief; and (6) Evidence and Confidence. These topics are discussed in turn.


This article presents the level of awareness among Human Resources managers and professionals of an Austrian oil & gas company with regards to Green Human Resource Management (GHRM). This is an approach with focus on integrating environmental sustainability practices into various HR functions within an organization. In addition, it recognizes that HR plays a crucial role in promoting and supporting sustainability by aligning the related policies and practices when it comes to talent attraction and retention, diversity, equity and non-discrimination or training and organizational effectiveness. To collect the data, a qualitative research methodology was used. We aimed to deep dive on how the Human Resources function integrates the environmental, social and economic sustainability principles into the practices, policies and strategies of the organization. Thus, such actions involve long-term impact HR decisions and actions on the environment, society and on the overall well-being of employees and stakeholders. The theoretical framework of the article is based on how corporate sustainability is integrated as a component of the overall business and Human Resources strategy. Interviews in the area of Talent attraction & Retention (Recruitment), Diversity, equity and non-discrimination and Training & Organizational Effectiveness were conducted in order to deep dive on the synergies between sustainability and HR strategy approach. The finding of the study confirms that there is a relationship between the presence of GHRM and corporate sustainability in the Austrian oil & gas company where the interviews were conducted. The HR managers and professionals are aware of Green Human Resources Management, however there is space for improvement in building the right business capabilities for a sustainable environment. In this respect, organizations should implement strategic human resources management policies based on Green Human Resources Management concept, with more focus on selecting, developing and retaining green employees. By integrating sustainability principles into HR principles, organizations can contribute to a more sustainable and responsible future while fostering a positive workplace culture that attracts, develops and maintains top talents.


Introduction: Irradiation Uniformity Considerations for Laser Fusion Successful demonstration of laser-fusion feasibility is critically dependent on the ability to drive the implosion with a very high degree of symmetry over the whole time of the target irradiation. For direct-drive laser fusion, this implies an irradiation uniformity over the entire surface of the target, which should not deviate from perfect uniformity by more than = 1 % rms at any time.' Such uniformity can only be realistically achieved with a fairly large number of incident laser beams symmetrically disposed around the target.2 At the same time each of these beams must have a reproducible ontarget beam intensity distribution that must be the same for all beams and should also be as smooth as possible.3 (The exact definition of smoothness, including temporal variations of any microstructure in the intensity distribution, is under investigation at present and will not be discussed further in this section.) To maintain a high degree of irradiation uniformity over the entire laser-pulse duration, equal power in each of the beams is required at any time, hence the term "power balance." If all beams are power balanced then all beam energies are the same. Since experimentally it is much easier to measure laser-pulse energy than instantaneous power in each beam, energy balance has been recognized to be essential for laser fusion. Power balance is obtained as a consequence of energy balance if all beamlines are identical. However, typical high-power beamlines are not identical, the consequences of which are the subject of the present study.


Network-On-Chip (NOC) plays a vital role in on-chip communication infrastructure for Massively Parallel System On Chip environment. Large size NOC networks are prone to fault(s) on links and routers. This paper presents a fault tolerant routing algorithm by setting up bypass path around faulty nodes. Experimental evaluation shows significant reduction in latency and better reliability over an existing technique and the baseline network.


A complex examination of 122 patients with II and III stages of neoplasms were carried out for the purpose of definition of results of correction of disturbances of endothelial functions in operated patients with gastric cancer. All patients were exposed to radical surgical treatment. Endothelium function indicators and contents of circulating endothelial cells were studied. It is revealed that application of L-arginine and ACE inhibitor provides decrease in degree of endothelial dysfunction and damages an endothelium that correlates with decrease in frequency of postoperative complications, late complications in the form of development of recurrence and metastasises and mortality.


This paper discusses the applicability of the newly available, inexpensive, but highly capable digital computers to the implementation of control systems employing very high-order, detailed mathematical models of the processes being controlled, and the effect of the resulting systems on control system design. These systems operate by supplying, through simulation, data not otherwise available on process operating conditions.


This study aims to look at the effectiveness of dhikr in overcoming anxiety at the time the menopause. Menopause is a time where a woman is no longer menstruating, once a sign of transition from adolescence to old age. At the time of menopause is a major change in women themselves, the physical changes are obvious, such as the emergence of symptoms hot flash, wrinkled skin and others. Along with these physical symptoms are psychological changes were also made, one of the most common psychological symptoms experienced by the emergence of anxiety without any obvious causes? The cause of this anxiety is because she started to feel existence itself is threatened, because with the advent of menopause is a person not be able to bear children, will grow old and will be removed by children and husband. In addition there are some businesses that can be done such as religious beliefs and involve themselves in social and religious activities (Darajat, 1974). For Muslims worship prayer is most important. Usually when after praying continued with the dhikr. This can help to keep continuing to be relaxed and calm the soul. Dhikr is the praise that is spoken over and over again and addressed to Allah or prayers of praise or sing is sung during religious celebrations (Salim & Salim, 1991). Dhikr is one way to overcome anxiety, because usually when someone does dhikr heart becomes calm and peaceful. With prayer and dhikr menopausal women who are experiencing feelings of anxiety to overcome this bias a bit by bit and the individual is calmer and more resigned to accept it.


Sustainability of supply chain in economic systems and green supply chain management has widely attracted researchers' attention by raising awareness of environmental effects. On the other hand, the lean supply chain is another concept whose implementation in organizations is expected to result in improved sustainability in industries. The present study aims to analyze the policy-based roles of the lean supply chain and green supply chain concepts in the corporation sustainability by designing a system dynamics model of the supply chain in CHOUKA Iran Wood & Paper Industries Inc. To this end, after a review of the literature with collaborations from decision-makers and CHOUKA data, the system dynamics model was designed in Vensim, and the model was simulated in a 10-year horizon after verification. Considering the behavior of the variables and the Monte Carlo sensitivity analysis, the model was simulated in the horizon, the green supply chain policies, the lean supply chain management and CHOUKA's business profitability were designed and applied on the model both in separate and integrative manners, the results were compared, and the behaviors of the policies were analyzed. As for the findings of the model simulation, the selected combination of the policies of lean supply chain management and green supply chain management, as well as CHOUKA's business profitability, was proposed as the best integrative sustainability policy for CHOUKA Iran Wood & Paper Industries supply chain management. The results generally indicated that simultaneous implementation of lean and green supply chain policies leads to synergy in supply chain sustainability


Background: This study was conducted to determine the drug utilization pattern among geriatric inpatients in general medicine department of the hospital.Methods: An observational, prospective study was conducted for a period of six months (November 2016 to April 2017) among 200 geriatric patients; demographic details, education, occupation, diagnosis and drug details were recorded. The drugs were categorized by anatomical therapeutic classification (ATC) and defined daily dose (DDD) was calculated. The World Health Organization (WHO) prescribing indicators were assessed.Results: The majority of the patients (59%) were in age group of 60-69 years. Cardiovascular diseases were common among geriatrics. Most commonly prescribed drug was Pantoprazole (81.7%). Drugs were assigned with ATC/DDD codes according to the guidelines of WHO. Drugs prescribed by their generic names were 56.64% and 43% of drugs that were included in the National Essential Medicines List.Conclusions: Clinical pharmacist have to collaborate and work together with physicians in selecting and adjusting the dose among geriatric population in order to reduce development of potential adverse drug reactions, serious drug related complications and drug interaction.


We investigate theoretically the optical bistability of reflection at the interface between graphene and Kerr-type nonlinear substrates. We derive a simple procedure to calculate the nonlinear reflectivity with graphene, and discuss the influence of the graphene sheets on the hysteretic response of the TM-polarization reflected light. It is found that the bistable behavior of the reflected light can be electrically controlled via suitably varying the applied voltage on the graphene. In THz, the bistable thresholds can be lowered markedly by increasing the Fermi energy. However, in near-infrared frequency, it requires multiple graphene layers to exhibit significant influence on the bistable thresholds.


A sponge roller (211), cleaning roller component (210), and floor cleaner. The sponge roller (211) comprises an inner sponge layer and an outer sponge layer, and the outer sponge layer is sleeved on the inner sponge layer. The inner sponge layer is made from non-absorbent sponge, and the outer sponge layer is made from absorbent sponge. Such sponge roller can be formed with a large thickness, andaccordingly improves the cleaning effect of the cleaner. Since the portion absorbing water is primarily the outer sponge layer, water can be squeezed out of the roller without using an excessive force; thus no excessive obstruction to the sponge roller is formed, and unnecessary energy consumption is prevented.


The transport phenomena of the photo-carrier generated through ππ* excitations in PET at 300 nm have been investigated. The steady state photocurrent can be explained from the space charge limited current theory, when a sufficient carrier reservoir at the cathode is maintained by photo-carrier generation at high light intensity. At low light intensity, a deviation from the theory occurs at high electric fields. This deviation is discussed and the spatial distributions of the internal field and carrier density are estimated for both good and poor reservoirs.


The recently published1, multi-site, FLASH-UK, randomized controlled trial (n=156, males 56%, Baseline HbA1c 71±9 mmol/mol, age 44±15) showed improved HbA1c and sensor-based metrics in adults with type 1 DM and an HbA1c ≥58 mmol/mol. Here we present results from pre-specified subgroup analysis for HbA1c (Table 1) and "Time in range (TIR)" (Table 2).
 The effect of isCGM on both HbA1c and TIR did not differ significantly across subgroups for baseline HbA1c category, treatment modality, prior structured education, sex, deprivation status or depression category. The effect of isCGM on HbA1c was larger for younger people. Those with at least a bachelor's degree had greater TIR improvement.
 Conclusion: isCGM is effective across a range of clinical and demographic factors.
 1N Engl J Med. 2022 Oct 20;387(16):1477-1487

 L.Leelarathna: Advisory Panel; Abbott Diabetes, Medtronic, Insulet Corporation, Sanofi, Research Support; Abbott Diabetes, Novo Nordisk, Speaker's Bureau; Sanofi, Abbott Diabetes. V.P.Taxiarchi: None. M.Burns: None. M.E.Camm: None. H.Thabit: Advisory Panel; Dexcom, Inc., Roche Diabetes Care, Research Support; Dexcom, Inc., Speaker's Bureau; Eli Lilly and Company. E.G.Wilmot: Advisory Panel; Abbott Diabetes, Dexcom, Inc., Eli Lilly and Company, Insulet Corporation, Medtronic, Novo Nordisk, Sanofi, Roche Diabetes Care, Embecta, Consultant; Springer Healthcare, Research Support; Abbott Diabetes, Diabetes UK, Insulet Corporation, Novo Nordisk, NIH - National Institutes of Health, Speaker's Bureau; Abbott Diabetes, Dexcom, Inc., Eli Lilly and Company, Insulet Corporation, Medtronic, Novo Nordisk, Sanofi, Ypsomed AG, Glooko, Inc. On behalf of the flash-uk trial study group: n/a. C.J.Sutton: None. M.Evans: Advisory Panel; Zucara Therapeutics, Pila Pharma, Dexcom, Inc., Other Relationship; Novo Nordisk, AstraZeneca, Abbott Diabetes, Speaker's Bureau; Eli Lilly and Company. S.Neupane: Advisory Panel; Quin, Abbott Diabetes, Roche Diabetes Care, Insulet Corporation, Other Relationship; Abbott Diabetes. G.Rayman: Other Relationship; Diabetes UK, Novo Nordisk, Research Support; Abbott Diabetes, Speaker's Bureau; Abbott Diabetes, Lilly Diabetes, Sanofi. S.Lumley: None. I.C.Cranston: Research Support; Eli Lilly and Company, Speaker's Bureau; Abbott Diabetes, AstraZeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, Insulet Corporation, Novo Nordisk, Sanofi, Viatris Inc. P.Narendran: Advisory Panel; Omnipod, Speaker's Bureau; Abbott Diabetes, Lilly Diabetes. K.Barnard: Advisory Panel; Abbott Diabetes, Roche Diabetes Care, Sanofi, Consultant; LifeScan Diabetes Institute, Tandem Diabetes Care, Inc., Research Support; Novo Nordisk.

 Diabetes UK (18/0005836)


Remark 6.1. Motivation. The time-dependent Navier–Stokes equations (1.24) were derived in Chapter 1 as a model for describing the behavior of incompressible fluids. From the point of view of numerical simulations, one has to distinguish between laminar and turbulent flows. It does not exist an exact definition of these terms. From the point of view of simulations, a flow is considered to be laminar, if on reasonable grids all flow structures can be represented or resolved. In this case, it is possible to simulate the flow with standard discretization techniques in space, like the Galerkin finite element method. In addition to the discretization in space, the simulation of time-dependent flows requires a discretization of the temporal derivative of the velocity. There are a number of so-called time stepping schemes available which lead to a variety of different algorithms for the numerical simulation of the time-dependent Navier–Stokes equations. 2


There are different loudness calculation procedures, such as the German standard DIN 45631/A1 and the proposed international standard ISO 532-1 as well as the Dynamic Loudness Model (DLM) (by Chalupper and Fastl), the Time Varying Loudness (TVL) model (by Glasberg and Moore), and the loudness calculation algorithm based on a hearing model of Sottek, allowing for the prediction of the perceived loudness of time-varying sounds in many cases. However, recent studies show that the predictions for some impulsive sounds do not match the ratings of normalhearing subjects. Therefore, the influence of specific signal properties of the sounds on the assessment of loudness was examined focusing on the impulsiveness of the sounds. On the basis of these experiments, it was studied to what extent the loudness model based on the hearing model of Sottek must be adjusted to take into account the specific signal properties of impulsive sounds.


The COVID-19 outbreak has inevitably changed the situation in Indonesia and might bring a threat to gender equality. This short paper aims to explain the impact of the COVID-19 pandemic on women from health, economic, and social aspect in Indonesia. First, from the health aspect, women are vulnerable to COVID-19 since they play the main role in the care economy. Also, the pandemic situation has changed the regulation of reproductive health services and might intensify the unmet need of women on reproductive health care. Second, from the economic aspect, the pandemic has hit Indonesia's economic situation and increases the unemployment rate as well as the informal worker on women. In addition, women also might be harder to return to market labor since it might be a limitation after the pandemic. Third, from the social aspect, due to working from home (WFH) regulation, women more likely to face a double burden to balance their productivity and domestic work. Not to mention that during the pandemic, the domestic violence to women has increased yet slower the responsiveness of the stakeholder to handle the reports. Â


Variable-width variable-thickness laminated composite beams provide stiffness-tailoring and mass-tailoring design capabilities. They are increasingly and widely being used in engineering applications including robotic manipulators, aircraft wings, space structures, helicopter blades and yokes, turbine blades, and civil infrastructure due to their enhanced stiffness-to-weight and strength-to-weight ratios.


The scope of the residential quarters in the cities is extensive, the floor is high and the buildings are close to each other, the population in residential quarters is dense. So it is necessary to make and complete the fire fireproof plan for overall position, the water supply plan for fire fighting, and the plan for communication, etc. These measures can reduce the lose of conflagration.


How does today's process industry engineer even specify a motor with the plethora of industry standards from various standards development organizations around the globe? This article provides a basic overview of the issues that are essential in the decision process when purchasing a new motor and is directed toward the engineer who must specify motors but is not a motor specialist. Since project engineers are regularly expected to justify the options selected and purchase recommendations, this article provides guidance. Process industry motor standards are used in reviews of motor requirements and options available today.


Nine patients had no symptoms of a bradycardia prior to pacemaker insertion. The rest of this report is concerned with the remaining 92 patients (54 men, 38 women, aged 32-97 years); 64 patients had predominantly atrioventricular block, 27 had predominantly sinoatrial disease, and one showed a mixed picture. The time from the onset of symptoms to permanent pacemaker insertion was more than 10 years in four patients. Two were women, aged 87 and 92 years at the time of implantation, who were known to have atrioventricular block. Another was a 62 year old man, with sinoatrial disease, who was being treated for epilepsy. The fourth was an 81 year old woman with initially no clear diagnosis, who was subsequently found to have sinoatrial disease. Nine patients had been waiting for 310 years: a cardiac arrhythmia had been identified in only one. More than six months had elapsed between the onset of symptoms and permanent pacing in 36 patients (39 per cent). Increasing age was not associated with a longer delay,


Steele et al.(1) make a number of worthwhile points about unwitting interdependence between performance scoring and weighting in multicriteria methods used for environmental decision making, but I find their presentation of this as "new news" mystifying. The sensitivity of both preferences (values, utilities) and weights (importance values, priorities) to the range of performance scores encountered in a particular problem analysis is fundamental to both the theory and practice of multiattribute utility analysis, and Steele et al.(1) cite the "bible" for that form of multicriteria analysis, Keeney and Raiffa's seminal book first published in 1976.(2) They then ignore these fundamental principles in the wind energy example they present in their paper. They present the "extreme" and "target" ranges for the two criteria in their wind energy example with a common assumption of linear utility, but this is a disingenuous "straw man." If the target range is small enough, the utility function expressing preferences for levels of any criterion will be linear. Conversely, it is hard to imagine any criterion for which utility would not become nonlinear if the performance range were very wide. Assuming equal weights on the two criteria regardless of the range of performance is equally disingenuous. Of course, weights should depend on the range. In a comparison between a red car and a blue car, whether the price differential between them is $10 or $10,000 will make a huge difference to the weights on price versus color. This "news" is at least 30 years old. And, it is mistake No. 8 in Keeney's(3) paper listing 12 common mistakes in making value trade offs.


The curriculum reform is affected by many factors, the rapid development of our country's social economy, higher education from elite to popular transformation of the key period, the reform of e-commerce curriculum is imperative, this paper analyzes the current e-commerce curriculum reform is facing obstacles, and points out its reform strategy.