The influence of the rotational effects on two-dimensional fluid convection in a rectangular enclosure with rigid walls during the orbital flight is considered. It is shown that the Coriolis force influence both on steady and oscillatory convection becomes significant at Ekman numbers which are quite attainable in the space orbital conditions. In the case of harmonic oscillations of the gravity force appearance of the resonance phenomena is demonstrated. Dependence of the height and shape of the resonance peak on aspect ratio of a rectangular domain and orientation of vectors of the gravity force and the angular rotation velocity is studied. Special attention is given to non-linear effects caused by convective terms of Navier-Stokes equations. The convection produced by variations of the angular rotation velocity of a spacecraft is also discussed. It is shown that in some cases the latter convection can be comparable with another kinds of convection.


Xenon is not only a technologically important element used in laser technologies and jet propulsion, but it is also one of the most accessible materials in which to study the metal‐insulator transition with increasing pressure. Because of its closed shell electronic configuration, xenon is often assumed to be chemically inert, interacting almost entirely through the van der Waals interaction, and at liquid density, is typically modeled well using Leonard‐Jones potentials. However, such modeling has a limited range of validity as xenon is known to form compounds under normal conditions and likely exhibits considerably more chemistry at higher densities when hybridization of occupied orbitals becomes significant. We present DFT‐MD simulations of shocked liquid xenon with the goal of developing an improved equation of state. The calculated Hugoniot to 2 MPa compares well with available experimental shock data. Sandia is a mul‐tiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for...


Adiponectin, a protein hormone produced by adipocytes, is also found in breast milk, which in turn is implicated in childhood obesity prevention. Although a biological role for adiponectin has not been firmly established, clinical and experimental research indicates that it regulates lipid and glucose metabolism, affects foetal development, and exerts anti‐inflammatory and antiatherogenic effects.


It is recognised that water is a key resource for life and development. The UN recommends a minimum of 50 litres of water per person per day to drink, wash and cook. Water scarcity and climate change form a dual challenge to food and environmental security. There are number of industries consuming large volume of water for the production of various products. Simultaneously, it releases equal volume of wastewater into the environment. It creates lots of additional problems to human beings as well as to sustainable environment. More dangerously, the ground water is also contaminated and thereby reduces the accessibility of potable drinking water to the consumers. Recycling of wastewater by using a novel green technology an "environmentally sound technology" is more suitable option. In this context, a new nano-biocarbon technology is developed by using biomaterials and is effectively used for treatment of highly contaminated wastewater. In the present study, a CETP grey wastewater is used for the treatment. The results indicate that, the nano- biocarbon technology works well and all the parameters are significantly reduced. The main pollution parameter such as COD and BOD is reduced to 86.98 and 81.17%, respectively. Alkalinity of the wastewater is reduced to 70.32% by making the water suitable for crop irrigation. After the treatment process, the concentration of heavy metals such as Cr (81.75%), Pb (85.79%) and Ni (90.40%) are significantly reduced. Setaria glauca was grown by using the treated wastewater and total biomass weight of 2.5 kg per pot was produced.


Temozolomide (TMZ)‐based chemotherapy is a standard strategy for glioma, while chemoresistance remains a major therapeutic challenge. Recent evidence highlights the crucial regulatory roles of long non‐coding RNAs (lncRNA) in tumor biology. However, the roles and regulatory mechanisms of lncRNA cancer susceptibility candidate 2 (CASC2), in glioma tumorigenesis and chemoresistance are poorly understood. In this study, CASC2 expression was down‐regulated in glioma tissues and cell lines, and was related to a clinicopathologic features and shorter survival time. Exogenous CACS2 alone was sufficient to inhibit glioma cells' proliferation and amplified TMZ‐induced repression of cell proliferation, while CACS2 knockdown could reverse this process. CACS2 overexpression could sensitize TMZ‐resistant glioma cells to TMZ, while CACS2 knockdown exerted the opposite function. Moreover, CASC2 could inhibit the miR‐181a expression by direct targeting in TMZ‐resistant glioma cells. CASC2 up‐regulated PTEN protein and down‐regulated p‐AKT protein through regulating miR‐181a, and the effect of CASC2 on PTEN and p‐AKT could be partially restored by miR‐181a. With TMZ‐resistant glioma tissues, miR‐181a was up‐regulated while PTEN was down‐regulated. Taken together, these observations suggest CASC2 up‐regulates PTEN through direct inhibiting miR‐181a and plays an important role in glioma sensitivity to TMZ and may serve as a potential target for cancer diagnosis and treatment. J. Cell. Biochem. 118: 1889–1899, 2017. © 2017 Wiley Periodicals, Inc.


The application of Data mining has proved to be successful in almost all the fields including medical domain. Medical data mining is the process of extracting useful knowledge and hidden patterns from medical data. This paper proposes a hybrid model for classifying Cleveland Heart dataset with hybrid feature selection and compares the performance with the base classifiers and ensemble classifiers. The model is developed in four stages. In the initial stage, Cleveland Heart dataset selected from the UCI repository is cleaned by deleting all the instances with missing values. In the second stage Fuzzy and Rough Set is used in a cascaded fashion for relevant feature extraction. In the third stage the resultant dataset was clustered into two segments using K-means and incorrectly clustered samples were eliminated to get final samples. Finally, the correctly clustered samples from the previous stage was trained with 5 different classifiers to build the final classifier model using 10 fold cross validation. Experimental results proved that proposed hybrid model showed enhanced classification accuracy compared to base classifiers and ensemble classifiers. It yielded highest accuracy of 99.54%.


The application of fluorescence spectroscopy methods to determining the properties of analogues of camptothecin, promising anticancer agents, are described in this paper. The fluorescence anisotropy measurements provide useful information about the binding of camptothecin and its analogues to cell membranes and human serum albumin (HSA) that is important for potential clinical applications of these agents, and permit the selection from many camptothecin analogues those ones exhibiting desirable biomedical properties. Fluorescence anisotropy measurements prove that 3 new camptothecin analogues: 7-tert-butyldimethylsilyl-10-hydroxy-campthothecin, 7-trimethyl-silylethyl-10-hydroxy-camptothecin and 7-trimethyl-silyl-ethyl-10-amino-camptothecin exhibit high affinity of their lactone forms to membranes and low affinity of their carboxylate forms to HSA. Such properties should ensure high stability of these agents in physiological fluids, including blood.


For applications like missile warning and automatic target recognition, AIM is presently launching its new 3rd generation high speed dual-color module. The focal plane array (FPA) is a mercury cadmium telluride (MCT) 192x192 56micrometers pitch device in a dual-color mid wave (MWIR) design. The module provides spectral selection with temporal and spatial coincidence for both colors using a new AIM proprietary technology. The spectral bands presently selected are 3.4-4 and 4.2-5micrometers with a full frame rate of 870Hz. Prior to the new devices, a sequential multicolor MCT camera with broadband detector and spectral selection using a rotating filter wheel was developed and evaluated. Results are shown to demonstrate the capabilities of spectral selective detection specifically for clutter and false alarm suppression in missile warning applications. A new algorithm was developed to allow highly sensitive detection of missile plumes without any need for non-uniformity correction for long-term stable operation and maximum dynamic range. An outlook is given on new activities at AIM on dual-band devices. The dual-band approach combining mid wave (MWIR) and long wave (LWIR) detection is specifically useful in automatic target recognition. The application, existing devices and the design goal of the new dual-band device are discussed together with experimental results.


The investigation was carried out in Jesus Maria parish of the Naranjal canton, province of Guayas, which is one of the provinces with the highest banana production per hectare, it is in second place even though its production has been decreasing through the last years being so that in 2015 its production was represented by 33%, in 2016 32% and in 2017 26% being these the periods of study. The small banana producers of this parish are in limited conditions since their income per banana box is not what is expected, which causes their living standards to be lower, for this reason the small producers of this parish have opted for other alternatives such as How to grow cocoa to improve your income and thus be able to support the needs of your family, it should be stressed that not all have taken this measure.

For the above mentioned, an analysis was made to know the financial situation of the small
banana producers in Jesus Maria Parish, at what price is their product purchased, in the same way to know the main factors in the low profitability, all this is done In order to inform government institutions of the situation of small producers so that they take the necessary measures that benefit the small producer and ensure their rights as it represents one of the most relevant factors of the Trade Balance……


Sesame is one of the main oil crops in China,but its yield of per unit area and slow improvement has limited its production.To slove this problem many researches of its expression and utilization way have been done.Some good methods to increase its productivity have been developed.


Global warming is likely to reach 1.5°C
between 2030 and 2052, if it continues
to increase at the current rate, as per the
report released in October 2018 by the
Intergovernmental Panel on Climate Change.
Climate related risks for natural and human
systems are higher for global warming of
1.5°C than at present. Global atmospheric
concentration of CO2 has increased from
preindustrial level of 280 parts per million
(ppm) to 409 ppm in December 2018. Studies
show that climate change in India is real and
it is one of the major challenges faced by
Indian agriculture, more so in the semi-arid
tropics (SAT) of the country. ICRISAT under
the National Initiative on Climate Resilient
Agriculture (NICRA) project, quantified the
changes in areas under different climates in
India and their study indicated increase in
the semi-arid areas in the country...


This study was conducted to evaluate the nutrition knowledge and eating attitude among female adolescent students (mean age 18.49+1.3 years) of University of Delhi. The sample comprised of 50 university first year undergraduate adolescent girls from colleges of Delhi University drawn by purposive sampling technique. The tools in the study included Nutrition Knowledge questionnaire that was designed and pretested by the researcher consisting of questions related to general information, meal pattern and nutrition knowledge. Eating Attitude TestEAT -26 was used to study eating attitude. Mean and Standard Deviation of the scores were calculated. Product moment coefficient of correlation (r) was computed in order to determine the dimensions of Nutrition knowledge influence on determining the eating attitude. The results were tested at 0.05 level of significance. The mean and standard deviation of Nutrition knowledge score was 21.5+3.04 and Eating Attitude score of these subjects was 19.4 +1.08. Relation between the nutrition knowledge and eating attitude revealed an inverse relationship and the non-significant correlation was observed (r= -0.13). The findings revealed that these students should not only improve upon nutrition knowledge but also should also be advocated on advantages of adopting right dietary Behaviours on overall health.


In his extensive work on tragic fragments, Martin Cropp has necessarily been occupied with the accidents of survival. Tragedy's particular concern with survival is in part related to the prominence of the bystanders. The violent deaths and extreme sufferings that are tragedy's main subject are difficult to represent and excruciating to witness, and classical Athenian tragedy is constituted in such a way that those events are made present to the mind but kept largely out of view. And tragedy retains from its roots in non-dramatic lyric a prominent chorus, which represents a group of people whose involvement in the action is intensely felt but also peripheral, a group who are always present from beginning to end, and always destined to survive whatever destruction the plot unleashes. This chapter picks up some of the threads of earlier discussion and following them into the plays of Sophocles. Keywords: Athenian tragedy; chorus; Martin Cropp; plays; Sophocles; survival; tragic bystanders; tragic fragments


low strain rate tests (SSRT) were conducted to determine the susceptibility of the 17-4-PH type steel to stress corrosion cracking (SCC) in simulated low pressure (LP) steam turbine environments. Environments tested included solutions of NaCl, NaOH and Na2S04 at different pH values, electrochemical potentials, concentrations, mixtures and strain rates at 95°C. It was concluded that this steel was susceptible to SCC in acidic NaCl solutions and with the application of both anodic and cathodic potentials and lowering of the strain rate. It is concluded that both hydrogen embrittlement and anodic dissolution mechanisms are responsible for the SCC susceptibility.


What the Middle Neolithic Alvastra pile dwelling in Ostergotland, Sweden, was used for has been discussed since the site was discovered in early 20th century. The interpretation by Mats Malmer of t ...


With the development of mobile internet technology,various terminal devices arise at the historic moment.The personal affairs synergy has great research value.Combining the personal affairs collaborative process and the characteristics of"closely linked to the people",this paper proposes a transaction coordination model based on tree structure.The data transmission and storage mechanism of the model are studied.The management,distribution,tracking and feedback of personal affairs on the multiple terminal platform are implemented.


The battle between the United States and European Union in the field of geographical indications(GIs) has heavily affected East Asia.Firstly,it results in the formation of GIs protection awareness in East Asia.The concept of GIs is transplanted and the domestic GIs legal systems are established.Secondly,it causes different standpoints with regard to the protection of GIs in East Asia.Japan and Taiwan stand by the United States,while Mainland China and Korea remain neutral.Thirdly,the international conflict of GIs in East Asia is focused.It is pointed out that those countries which adhere to neutrality will show their attitudes gradually,and the cooperation between government and industrial associations should be the main trend of the protection of GIs in East Asia.


With the development of economic globalization, more and more agricultural enterprises expand their products market to other countries, it will not only increase enterprise's profits, but also rich foreign markets of agricultural products. However, because of the limitations of their own development of agricultural enterprises, they have poor brand awareness, and even take Brand-Sticking Strategy in international trade; all of these have hampered enterprise's long-term sustainable development seriously. This paper will analyze enterprise's international marketing based on USP theory.


this paper describes the design considerations associated with the development of a flare guidance subsystem for the time reference scanning beam (TRSB) microwave landing system (MLS). The two basic concepts for providing MLS flare guidance information are examined; the touchdown zone and wind model are defined; technologies and equipment that are candidates for providing flare guidance are identified; the advantages of the MLS in providing a transition capability from glide slope to altimetry are discussed; various flare algorithms are tabulated; flare antenna option is presented with configuration decision guidelines; and flight test results are shown that demonstrate the guidance capability of the elevation antenna in the approach threshold vicinity.


Interfacial charge separation in hybrid solar cells depends on the energetic alignment and electronic coupling between the inorganic and organic semiconducting materials at the hetero-interface. In ...


The authors previously reported that the two groups of lingual glands of the adult chicken differed from each other in histological aspects (TORYU et al.1)). The glandular cells of the anterior lingual glands are smaller and contain less mucin in the cytoplasm with larger and lighter nuclei than those of the posterior lingual glands. The prominent occurrence of glycogen in the nuclei of anteriorgland cells was noted in the laying hen, but not in the cock. No glycogen-laden nuclei were found in the cells of the posterior lingual glands. It was considered that the occurrence of glycogen in the nuclei was most likely to have some very important significance connected with the laying activity of the hen. Since no references concerning the occurrence of glycogen-laden nuclei are available so far as the present authors know, further investigation should be performed on this phenomenon. In the present study, the occurrence of glycogen-laden nuclei in the anteriorlingualgland


Transmetallation of bulky 1-arylthio-2-(2,4,6-tri-t-butylphenyl)-2-phosphaethenyllithiums with copper(II) and mercury(II) afforded the corresponding 1,4-diphospha-1,3-butadiene derivatives as homocoupled products and organomercury compounds, respectively, which were analyzed by X-ray crystallography.


At the heart of most academic and political debates regarding the future of the European Union lie three key ideas: openness and transparency; citizens' participation in the decision-making process; and democratic legitimacy. Scholars and EU policy-makers have advocated the use of new media, particularly the Internet, in the democratising process of the EU. T his article focuses on the top-down aspect of the online European public dialogue and the opportunities that the EU's public communication strategy offers to citizens for involvement in shaping the Union's political nature. Following a 'multi-method' approach for the gathering of empirical data, the Internet's role in the EU's public communication strategy is examined here from four aspects: the European Commission's public communication policies (document analysis); the Commission's implementation of its online policies (website analysis); their impact on key Internet audiences (user survey); and the views of policy-makers (semi-structured interviews with senior Commission officials).


Objective To observe the ocular manifestations and therapeutic effect of multiple sclerosis (MS) and neuromyelitis optica (NMO) with ocular symptoms. Methods The clinical data of 107 patients who was diagnosed with MS and NMO with ocular symptoms in our hospital were retrospectively analyzed, including 81 MS patients and 26 NMO patients. The counting of erythocytes and leukocyte, protein content and oligoclonal bands were detected by MRI and cerebrospinal fluid (CSF) in order to ensure the clinical diagnosis with MS and NMO. All the patients had undergone regular ophthalmologic examination of visual acuity,slit lamp microscope and fundus examination. In addition, visual field and visual evoked potential (VEP) examination were performed to analyze the clinical characteristics of ocular manifestations. The patients were received therapy with large dose methyl-prednisolone or activating blood and dissolving stasis and trophic nerve by Chinese medicine. The effects of three methods on ocular manifestations were analyzed. All the patients were followed up for one month to five years. Results Among 81 MS patients,retrobulbar neuritis occurred in 24 patients (29. 6%), the other common symptoms included paralytic strabismus and diplopia(30.3%). Among 26 NMO patients, acute papillitis occurred in 12 (46. 2%), while retrobulbar neuritis occurred in 14 (53. 8%). The most common symptom of both MS and NMO was impaired vision and high abnormal rate. The results of MRI showed that demyelinating lesions beside ventricle was the most performance in MS patients,while abnormalities in spinal cord were found in NMO patients. The results of CSF showed that the positive oligoclonal bands was 75.3% and 19.2% in MS and NMO patients respectively. The potential time delay and (or) amplitude declination were observed by VEP. Large dose methyl-prednisolone can improve vision and diplopia in a short period. Conclusion The abnormal ocular manifestations of MS and NMO patients are common and complicated. Ocular symptoms has important reference value in the early diagnosis of MS and NMO.

Key words:
Optic nerve diseases/etiology,Multiple sclerosis/diagnosis; Multiple sclerosis/therapy; Neuromyelitis optica/diagnosis; Neuromyelitis optica/therapy


Bovine paratuberculosis (PTB) causes major economic losses to dairy farmers because of decreased milk production, poor body condition, weight loss and early culling. The aim of this study was to evaluate the effect of Mycobacterium avium subspecies paratuberculosis (MAP) infection on carcass weight and age at slaughter in Friesian cattle. A total of 1,014 adult cows slaughtered at two local abattoirs in the Basque Country were included in this study. MAP infection was determined by different methods: indirect ELISA on blood samples, detection of MAP in tissues by culture and real time PCR (rtPCR), and histopathological examination. Serial and parallel interpretations of these methods were also considered for setting the upper and lower infection rates. MAP infection was confirmed by at least one test in 58.9% of animals. Most infected cows were detected by histopathology (46.9%) and rtPCR (29.6%). Overall estimates of carcass mean weight losses ranged from 3.7% for cases identified by the presence of microscopic specific PTB inflammatory lesions to 12.4% for cases with positive results in the paratuberculosis antibody ELISA test. Isolation of high bacterial loads in tissues and occurrence of diffuse granulomatous enteritis were associated with the highest weight loses, 22.2% and 26.0% respectively. The life expectancy of seropositive cows and those showing diffuse lesions was reduced by nearly one year compared to that of non-infected ones. Our results provide consistent evidences of PTB effect on the reduction of slaughter weight and lifespan of dairy cows, which could be considered as surrogates of clinical disease.


An extension of thc variational analysis of Gaussian beam propagation in nonlinear Kerr medium is presented. The variational equations obtained for the nonlinear Schroedinger equation (NSE) are analyzed using a qualitative theory of dynamical systems. The soliton part of the total field is found to be the critical point of the phase-space of dynamical system determined by variational equations. The approximate solution of these equations provides oscillations of the total field around a soliton solution. The results show a very good agreement with predictions of the Inverse Scattering Transform.


This letter proposes a new travel time estimation model based on graph neural network (GraphTTE) to improve the accuracy of travel time estimation. We design a Multi-layer Spatiotemporal Graph frame (MSG), which consists of static network and dynamic networks, to fully consider the influence of traffic temporal characteristics and road network topological characteristics on travel time. Moreover, we design an Attention Graph Nodes Impact Index algorithm (AGNII) to score the impact of each node on travel time. In particular, the dynamic networks utilize the graph convolution network and gate recurrent unit to obtain the traffic characteristics, the static network utilizes graph convolution network to obtain the road basic attributes. We combine the real paths sequence with the impact score of nodes to extract the subgraph with a great impact on the trajectory. After the graph representation learning and deep residual network, the estimated time is obtained. A simulator was designed to train and test our model in Chengdu and Xi'an datasets, the results show that the mean absolute percent error (MAPE) is 12.58% and 14.01%, which is 1.54% and 1.78% lower than the baselines.


Areas of high Cuban concentration in South Florida... vote more frequently and more conservatively than the average, offering a marked contrast with the political behavior patterns of Hispanic districts elsewhere in the United States. Reasons for this unique trend are not found in the defense of a privileged economic situation; although the data cannot support a definite conclusion, they point again in the direction of the unique history of this minority and the attitudes rooted in its home country experience as the prime determinants of its current behavior (my underlining).


Students with learning disorders are one of the largest and fastest growing populations of college students with disabilities, yet many experience significant difficulty in formal academic settings. These challenges may include lower levels of academic achievement, negative perceptions of school, and negative perceptions of themselves. Research has shown that certain variables, including implicit theory of intelligence, goal orientation, and self-efficacy, are related to academic achievement. The current study sought to assess the relationships between these variables and academic achievement, as measured by cumulative GPA, among a sample of college students with identified learning disorders. Results showed medium to large correlations between self-efficacy scales and GPA. There was no relationship between implicit theory of intelligence and college GPA, though a small negative relationship with high school GPA. Additional small correlations were found between goal orientation and GPA, implicit theory of Running head: PERCEPTIONS OF INTELLIGENCE iv intelligence and goal orientation, and implicit theory of intelligence and self-efficacy. When compared to a control group, students with learning disorders had similar GPAs and were no more likely to endorse a fixed view of intelligence. Though this sample did not differ significantly from the control group, some of the relationships among the variables may warrant further investigation as areas of intervention among this population. Running head: PERCEPTIONS OF INTELLIGENCE v


Summary Potent culture fluid preparations of β-glucuronidase are obtained when E. coli is grown at 25°C and pH 7.3 in a simple medium containing menthyl-β-glucuronide. The optimum incubation time is 8 days when continuous agitation is employed. The optimum pH for the hydrolysis of phenolphthalein mono-β-glucuronidei is 6.2, while that for estriol-4bT-glucuronide is 4.5-7.0. Bacterial β-glucuronidase is readily inhibited by ammonium ion. Dialysis markedly decreases the enzymatic activity of our preparations. The culture fluid contains phosphatase but no sulfatase activity.


Numerical models of a water system are always based on assumptions and simplifications that may result in errors in the model's predictions. Such errors can be reduced through the use of data assimilation and thus can significantly improve the success rate of the predictions and operational forecasts. The ensemble Kalman filter (EnKF) is a generic data assimilation method which is suited for highly nonlinear models. However, for three‐dimensional operational systems such as in the case of Osaka Bay, Japan, a full EnKF would be computationally too demanding. In the present paper, a steady state Kalman filter (SSKF) simplification based on the correlation scales derived from the EnKF is proposed. This EnKF‐based SSKF (EnSSKF) as presented in this paper is applied in combination with the three‐dimensional Delft3D‐FLOW system, modeling the stratified circulation system of Osaka Bay in Japan. The aim of the application of the EnSSKF is to improve the daily operational forecasts of salinity and current profiles for engineering activities within the basin. Salinity and velocity components were assimilated on an hourly basis for the period 13–28 February 2002. The results of the filter performance and its forecasting ability are presented. The performance of the EnSSKF for improving the profiles of salinity and velocity components forecast during the first 24 h forecast is illustrated.


This study was carried out to evaluate the effect of the product of commercial live bakers' yeast (Saccharomyces cerevisiae) so called Amax on the growth and survival of Persian sturgeon (Acipenser persicus) larvae via enrichment of Daphnia magna. The blends of Amax were used in three concentrations of 50, 100, 150 mg L with Daphnia in suspension of broth. Every day Daphnia by one of concentrations was bioencapsulated for 10 hours and Persian sturgeon larvae were fed on it. The Acipenser persicus larvae were fed from Daphnia on the base of the 50 percent of their body weight five times a day. The control group was fed on not enriched Daphnia. The gained body weight in experimental treatments of sturgeon larvae had significant difference compared to control treatment (p0.05). In experimental treatments, Food Conversion Efficiency was increased while the Relative Food Intake significantly decreased (p0.05). Food efficiency was increased significantly (p<0.05) in experimental treatments. The Amax had significant positive effects on the Specific Growth Rate (SGR), Average Daily Growth (ADG), Relative Gain Rate (RGR), Growth Conversation Efficiency (GCE), Daily Growth Coefficient (DGC) and Thermal Growth Coefficient (TGC) in comparison with control treatment (p<0.05). No significant difference in the condition factor was observed (P>0.05). The Amax had significant positive effects on survival rate in comparison with control treatment (p0.05). The experiments indicated that the product of Saccharomyces cerevisiae has a high ability to increase the growth parameters and feeding efficiency in cultivation system of sturgeon fish. Keyword: Saccharomyces cerevisiae, sturgeon, enrichment, Daphnia magna. هدیكچ . هدافتسا تارثا ھعلاطم نیا رد کاس ییاونان رمخم یردوپ هراصع زا ایسیورس سیسیامورا ) ناونع تحت Amax ( رپ ناونع ھب و يھام ورلا يیاذغ هریج رد كیتویب يناریا يھام سات (Acipenser persicus) تدم ھب لاعف ھیذغت عورش نامز زا 30 تفرگ رارق يسررب دروم زور . زا ھعلاطم نیا رد يناریا يھام سات ياھ ورلا نویسناپسوس ھس رد هدش ينغ يانگام ينفاد يزاس ي نغ يا ھ تظلغ ا ب 50 ، 100 و 150 يردوپ يرمخم لوصحم زا مرگ ي لیم رار ق ھ یذغت دروم،رتیل رھ رد دنتفرگ . اھرامیت ریاس جیاتن اب ھسیاقم يارب دھاش رامیت ياھورلا ھیذغت يارب هدشن ينغ ينفاد زا نینچمھ دش هدافتسا . ياھورلا ھیذغت سات يھام يناریا ناز یم ھب 50 دصرد نزو ندب و ھنازور رد 5 تبون زا ينفاد ماجنا دندیدرگ رد شیامزآ نیا بلاق لاماك حرط يفداصت ءارجا دیدرگ . دشررظن زا اھرامیت نیب هرود ياھتنا رد فلاتخا دشن هدھاشم يراد ينعم ) 05 / 0 > p .( هدش ينغ ينفاد اب ھیذغت دروم ياھرامیت نیب يراد ينعم فلاتخا يلو اب ھسیاقمرد هدھاشم دھاش رامیت دیدرگ ) 05 / 0 ( p< . رمخم رب يیاونان خرن دشر هژیو (SGR) بیرض دشر يترارح (TGC) يیآراك لیدبت ،اذغ خرن ءاقب و دیلوت نازیم ياھورلا سات يھام يناریا رد ھسیاقم اب رامیت ،دھاش تاریثات تبثم ينعمو راد دنتشاد ) 05 / 0 (p< . اب مراھچ رامیترد دشر دركلمع نیرتھب 150 یل رب مرگ يلیم رت Amax دیدرگ هدھاشم ) 05 / 0 (p< . ناشن شیامزآ نیا جیاتن ھتشاد يناریا يھام سات ياھورلا دشر ياھرایعم شیازفا رد يیلااب تیلباق ایسیورس سسیسیاموراكاس رمخم يردوپ هراصعزا هدافتسا ھك داد ياھ هریج ھعسوت رد و دوب دھاوخ دنمدوس يھام نیا يدربراك . يدیلك تاملك : راكاس رمخم رپ، ایسیورس سیسیامو و يناریا يھام سات،ينفاد،يزاس ينغ،كیتویب Introduction. The demand for animal protein for human consumption is currently on the rise and is largely supplied with terrestrial farm animals. This activity (aquaculture) requires high-quality feeds with high protein content, which should contain not only necessary nutrients but also complementary additives to keep organisms healthy and favor growth. Acipenser persicus Borodin, 1879 is an important species for freshwater aquaculture. Improving fish performance and disease resistance of cultured organisms are major challenges facing fish culturists. Therefore, several alternative strategies to the use of antimicrobials have been proposed, such as the use of probiotics as biological control agents. Probiotics, live microbes that may serve as dietary supplements to improve fish growth and immune responses, have received some attention in aquaculture (Gatesoupe 1999; Irianto & Austin 2002; Kesarcodi-Watson et al 2008). The application of probiotics and prebiotics may therefore result in elevated health status improved disease resistance, growth performance, body composition, reduced malformations and


After setting expected failure during power grid operation risk assessment, failure isolation contains two steps, one is to identify the switches that should be disconnected, which are called shift switches, the other is to disconnect the shift switches. This paper proposes a method of identifying shift switch of expected failure isolation, where substation topology and complex wiring are considered. First, from the viewpoint of failure isolating effect, failure elements are classified into independent elements and element groups. Second, element group and its composition are obtained according to its structural features. Then, the method of identifying shift switches of failure isolations for all kinds of failure elements is established. Finally, the proposed method is validated by applying it to classical failures of a practical power grid.


Abstract The purpose of this paper is to introduce and analyze two inertial algorithms with self-adaptive stepsizes for solving variational inequalities in reflexive Banach spaces. Our algorithms are based on inertial hybrid and shrinking projection methods. Knowledge of the Lipschitz constant of the cost operator is not required. Under appropriate conditions, the strong convergence of the algorithms is established. We also present several numerical experiments which bring out the efficiency and the advantages of the proposed algorithms. Our work provides extensions of many known results from Hilbert spaces to reflexive Banach spaces.


all‐trans‐retinoic acid (atRA) regulates many biological processes via RAR and PPAR mediated pathways. The metabolism and clearance of atRA is mediated by the CYP26A1 and CYP26B1 enzymes, that both appear to be critical retinoic acid hydroxylases during fetal development and adult life contributing to tissue specific regulation of atRA concentrations and signaling. CYP26A1 and CYP26B1 have different tissue specific expression both in adults and during development, and distinct switches occur between fetal expression patterns and adult tissues for both CYP26A1 and CYP26B1. In human fetal tissues CYP26A1 is exclusively expressed in brain, whereas CYP26B1 is not present in brain but found in other tissues. In adults, CYP26A1 is predominantly expressed in liver, whereas CYP26B1 is predominantly found in cerebellum and ubiquitously expressed in many other tissues such as adipose, testes, lymphocytes and kidney. While both CYP26A1 and CYP26B1 expression is believed to be regulated by atRA, the mechanisms that lead to distinct tissue specific expression and regulation of the CYP expression are not known. The aim of this study was to examine the tissue specific regulation of CYP26A1 and CYP26B1 by RAR and PPAR using various models of human liver, adipose and immune cells that reflect tissues specifically expressing CYP26A1 or CYP26B1. Our data revealed that constitutively CYP26A1 is predominantly expressed in liver cells, whereas CYP26B1 is found in adipocytes and lymphocytes. Similarly, CYP26A1 was highly inducible by atRA in liver cells while CYP26B1 was induced in adipocytes and lymphocytes. siRNA mediated knock down of nuclear receptors showed that CYP26A1 mRNA expression is solely regulated by RARα/β, whereas CYP26B1 expression is mainly regulated by PPARγ. These data suggest that the tissue specific expression of CYP26 enzymes is regulated by different nuclear receptors acting on the CYP26 promoter and that the two CYP26 enzymes will respond differently to endogenous and xenobiotic regulators of CYP expression. In conclusion, these findings may explain the different phenotypes observed after loss of CYP26A1 or CYP26B1 activity.


ABSTRACT School principals' decisions are made within the complex organizations called schools. This study explored how systems thinking is reflected in principals' perceptions about their decision-making processes. Based on a qualitative analysis of interviews and focus groups, principals' descriptions of their own effective decision-making reflected systems thinking in the following three areas: (1) expanding the number of choices; (2) identifying possible consequences of various alternatives; and (3) seeking and analysing relevant information. As school is an inherently complex organization, the findings of this study shed light on the connection between the complicated nature of principals' decision-making and systems thinking. Implications and further research are discussed.


The laser processing machine is used to cut the notch of big-end hole of connecting rod in engine at high speed.In this paper,a preprocessing method was proposed to study the acceleration and deceleration for a laser notching machine.In order to eliminate the overcut as well as the remains because of the importing M function,a look-ahead means was put forward to deal with the acceleration/deceleration of this laser notching machine.Then,a new NC processing program combining the result from the former program was presented.Finally,the connecting rod was splitted after laser cuting notch.By checking over the connecting rob in a microscope,the results show that the splitting notch is almost the same in the depths(the depth tolerances of all points are ±0.02 mm) for all types of connecting rods.Moreover,there are no overcut or remains at all.These conclusions illustrate that this means greatly improves the stability and precision of the laser notching machine.


ABSTRACT Carbon fibre-reinforced carbon aerogel composites (C/CAs) were prepared by using polyacrylonitrile (PAN) and phenolic (PH) carbon precursor fibres as reinforcements, respectively, then impregnated with resorcinol-formaldehyde sol, aging, solvent exchanging, CO2 supercritical drying and carbonization at 1000°C. The physical properties, structural morphology and mechanical and thermal insulation behaviour of the two kinds of composites were further compared. Pore structure analysis shows that the PH-based C/CAs have a larger specific surface area (438.92 m2·g−1) and richer mesoporous volume than the PAN-based C/CAs. Mechanical behaviour of the C/CAs has been changed, but the stronger enhancement effects belong to PAN-based C/CAs (compressive strength in xy and z-directions are 1.63±0.10 MPa and 1.22±0.19 MPa, bending strength is 3.62±0.50 MPa). However, the PH-based C/CA composites have relatively low thermal conductivities, ranging from 0.027 to 0.164 W·m−1·K−1 between 25 and 1800°C.


Over the last 225 years, government finances in the United States have gone through three distinct stages. In the first stage, 1790–1850, state governments actively pursued policies to promote economic development and financed them from revenues from state investments. In the second, 1850–1930, local governments became the most important level of government, as measured by revenues and expenditures, and revenues shifted toward the property tax. In the third period, 1930 to the present, the national government became the most active and largest level of government, financed through income and payroll taxes, and developed an extensive network of grants to state and local governments. The chapter tracks the changes in sources of revenues and purpose of expenditures, with specific attention paid to military spending over the entire period.


The errors of aperture synthesis microwave radiometers(ASMRs) have great influence on the performance of the system,and should be calibrated.However,it's difficult to calibrate the errors of ASMRs with large aperture and high working frequency.An error calibration method based on prior information for ASMRs is presented in this paper,which consists of a calibration matrix based on prior information and a CLEAN algorithm based on prior information.Firstly,the imperfect system response,as the prior information,is used to construct the calibration matrix,and a primary image can be reconstructed.Then,the array factor of ASMRs estimated from the prior information is introduced to the CLEAN algorithm and used to calibrate the remained errors in the primary image.Simulation and experiment results show the error calibration method can greatly improve the image quality of ASMRs.All the errors can be calibrated in image reconstruction by the calibration method,and the performance requirement of calibration hardware system is reduced.So this error calibration method is suitable for the error calibration of large millimeter wave aperture synthesis radiometers.


Characteristics of Team Leaders Play as exemplified by the European Championships In Basketball This paper presents a statistical analysis of basketball team leaders performance during a championship status tournament in team sports using the example of the 36th European Championships EuroBasket 2009. The list of player-leaders of particular national teams was developed by means of the expert method, based on the analysis of qualitative and quantitative data. Empirical data gathered were taken from the website of EuroBasket 2009 Poland (www.eurobasket2009.org) and FIBA Europe (www.fiba.com). Formal statistical methods concerning sample description were used. The comparative analysis was conducted by means of various tabular and graphic techniques. The calculations were performed in a STATISTICA spreadsheet. The applied statistical methods allowed a series of conclusions to be drawn concerning the performance of leader-players and their cooperation with other players on the court. The knowledge of particular SGCs (standard game components) realization allows those dispositions of leader-players which are especially significant in the process of cooperation in a basketball team to be improved by coaching.


With appropriate choice of conditions, copolymerization of monosubstituted monomers [CH2CHX:  e.g., styrene, butyl acrylate (BA)] in the presence of small amounts of an α-methylvinyl monomer [CH2C(CH3)Y:  e.g., α-methylstyrene (AMS), methyl methacrylate (MMA), methacrylonitrile (MAN)] and a cobaloxime as chain transfer catalyst provides a route to macromonomers that are composed largely of the monosubstituted monomer and yet have a chain end derived from the α-methylvinyl monomer (−CH2−C(CH2)Y). The various factors (temperature, concentrations, type of cobaloxime, types of monomer) that influence molecular weight and end group purity and the importance of the various side reactions that may complicate the process are described. Macromonomer purity is enhanced by increasing the concentration of the α-methylvinyl monomer and reducing the cobaloxime concentration. It also depends on the structure of the cobaloxime, increasing in the series where the ligands are derived from dimethyl glyoxime < diethyl glyoxi...


The diary entries of the author on his stay in London from the end of 1999 to the beginning of 2001 are presented. He records his disappointment at the failure of the referendum on Australia becoming a republic, and the various sights and sounds of England that he enjoyed during his stay.


A list channel assignment problem is a triple (G,L,w), where G is a graph, L is a function which assigns to each vertex of G a list of integers (colors), and w is a function which assigns to each edge of G a positive integer (its weight). A coloring c of the vertices of G is proper if c(v)\in L(v)$ for each vertex v and $|c(u)-c(v)|\ge w(uv)$ for each edge uv. A weighted degree $\deg_w(v)$ of a vertex v is the sum of the weights of the edges incident with v. If G is connected, $|L(v)|>\deg_w(v)$ for at least one v, and $|L(v)|\ge\deg_w(v)$ for all v, then a proper coloring always exists. A list channel assignment problem is balanced if $|L(v)|=\deg_w(v)$ for all v. We characterize all balanced list channel assignment problems (G,L,w) which admit a proper coloring. An application of this result is that each graph with maximum degree $\Delta\ge 2$ has an L(2,1)-labeling using integers $0,\ldots,\Delta^2+\Delta-1$.


ABSTRACT This study contributes to the debate on sustainability in higher education through a project conducted in a single Scottish university that incorporated sustainability into undergraduate accounting education through the application of a real-world problem in the form of a social and environmental report. Data from study participants were collected through questionnaires, which were analysed and interpreted through the lens of knowledge creation. The results demonstrate an increase in awareness and positive response to sustainability issues from all parties. It further indicates that opportunities to shape and develop further sustainability initiatives are possible through a dialogical approach. Such an approach is shown to provide an opportunity for knowledge creation and the transfer of sustainability issues in a democratic and emancipatory way. It highlights the importance of developing spaces/opportunities for sustainability dialogue that not only transcend the boundaries of a specific graduate discipline but also the borders of higher education institutions.


Lightning strokes are natural phenomena responsible for a large number of disturbances and interruptions in electrical systems. The investigation of their behavior can support operation strategies and installation and protection projects of power transmission lines. This research scope includes the study of joint development of lightning strokes, in space and time, as result of structured weather events called "electrical storms", and the analysis of their behavior near a selected electrical system. To identify and track these storms a clustering method of Convergent Data Sharpening is used, and to analyze the trajectories behavior formed by these storms regarding meteorological features the  Self-Organizing Map (SOM) is applied. Both methods are implemented in software package R. The study revealed that electrical storms that caused failures in the electrical system studied tended to have more lightning strokes than other storms and also had no peak current average greater than regular storms, what could be expected by the relevance of this variable in the electrical system disturbances.


THE INVENTION CONCERNS A DEVICE FOR TRANSFER OF GLASS SHEETS 1 A FIRST JOB, THEY ARE IN A POSITION SIGNIFICANTLY VERTICAL UP A SECOND JOB, THEY ARE IN A POSITION SIGNIFICANTLY HORIZONTAL. DEVICE INCLUDES 8 PORTAL SUPPORTING STRUCTURE BEAM 7 PREPARED ESSENTIALLY THE hORIZONTAL ABOVE THE GLASS SHEETS IN POSITION SIGNIFICANTLY VERTICAL STRUCTURE THAT SUPPORTING BEAM 7 ITSELF A CHASSIS 6 SUCKER 15 CONNECTED TO CIRCUIT dEPRESSION IN ORDER TO BRING SUCH TURN GLASS SHEETS AND ONTO A CHASSIS TIPPING 9 TO AN EXPERIENCED IN ITSELF WHICH PROMPTED BY ROTATION IN HORIZONTAL POSITION. ACCORDING THE INVENTION, THE STRUCTURE IS mOUNTED BEAM 7 SLIDING IN A HORIZONTAL PLANE OVER AUDIT PORTIQUE 8 UNDER THE MOTOR MEANS OF PROXIES.


As the Olympic flag was taken over by Rio de Janeiro at the closing ceremony on the night of August 12,the London 2012 Olympic Games wrapped up with a lively carnival party.Jacques Rogge, President of the International Olympic Committee(IOC),said in his address at the closing ceremony that the 30th Olympic Games were "happy and glorious."


AlN/GaN superlattices (SLs) employing various well widths (from 1.5 to 7.0 nm) are grown by metal-organic chemical vapor deposition technique at various growth temperatures (TS) (from 900 to 1035 °C). The photoluminescence (PL), x-ray diffraction, and intersubband (ISB) absorption characteristics of these SLs and their dependency on well width and growth temperature are investigated. Superlattices with thinner wells (grown at the same TS) or grown at lower TS (employing the same well width) are shown to demonstrate higher strain effects leading to a higher PL energy and ISB absorption energy. Simulations are employed to explain the experimental observations. ISB absorptions from 1.04 to 2.15 μm are demonstrated via controlling well width and growth temperature.


The invention discloses a space water new energy hot water system which comprises air energy hot water equipment, solar hot water equipment, a circulating water pump, a compression-resistant water squeezing tank, a valve used for a user, water pipes and a wastewater heat recovery plant, wherein, the wastewater heat recovery plant comprises a wastewater solenoid valve, a wastewater heater, a wastewater reservoir and a wastewater energy submersible pump; the wastewater heater comprises a condenser, an electronic expansion valve, an evaporator and a compressor which are sequentially communicated together via a Freon pipe to form a circulation loop; and the evaporator and the wastewater reservoir form the circulation loop through two water pipes, one of the water pipes is fixedly provided with the wastewater submersible pump at the end head of the in the wastewater reservoir, and the water pipe is positioned above the other water pipe. The space water new energy hot water system provided by the invention is reasonably manufactured by integrating a solar water heater, an air energy water heater and the wastewater heater, and the problems that the solar water heater and the air energy water heater can not supply hot water owing to weather influence at times and high-temperature domestic wastewater can not be well utilized are solved.


The arid coastal region of Ecuador and Peru belong to the regions experiencing the strongest impact of the El-Niño-Phenomenon. In spite of neutral to cold conditions after the decaying 2015/16 El Niño, unexpected by internationl scientists and local authorities alike, in 2017 the region was hit by torrential rain falls causing floodings, erosion and landslides with many fatalities and significant damage to infrastructure.

RadarNetSur (www.radarnetsur.de), initiated in 2012 to 2015 forms the first weather radar network in that region and was capable of monitoring the development of the 2017 event up to its culmination, providing insight into rainfall distribution (resolution of 500 m) on a 5-minute time step. The network consists of 3 X-Band-scanning weather Radars with a range of 60 to 100 km, thus covering 80000 km² from 2° S to 4°S. In 2019 the network was extended far into Peru with a new system in Piura.

We present results of the analysis of the event and compare it to the conditions in the years 2014, 2015 and 2016, to point out spatial patterns and process dynamics, which led to this unusual coastal El-Niño during central Pacific La-Niña conditions. Apparently, the isolated warming of the Niño 1+2 regions off the coast was the main driver of these strong rainfalls, but the local expression of weather patterns is shaped by topographic conditions interacting with the synoptical situation (West wind bursts) and small-scale circulation systems like the sea-breeze and mountain-valley breeze. Most intense rainfall is associated with disturbances in the divergence field which are intensified by changes of the synoptical flow direction.   We assume, that either the conventional understanding of the ENSO-impact on the regional scale is insufficient, or, the ENSO-phenomenon is slowly transitioning into a more complex behavior.


Abstract The view of managerial career success as an uninterrupted climb up the corporate ladder no longer fits the realities of many managers. This study examined longitudinal data on the career paths of MBAs to determine the consequences of early- and mid-career gaps on career success. The study found that early gaps have a negative impact on income and management level. Gaps in mid-career also reveal an income penalty, even after controlling for pre-gap income. In mid-career, the negative level effect was found for women, but not for men. MBAs with discontinuous employment histories, however, did not have diminished career satisfaction. The research suggests the need for researchers, organizations, managers, and business schools to broaden the definition of acceptable managerial career paths.


This paper is a part of our research to develop an animated film based on the wayang beber Pacitan visual form. Wayang beber Pacitan is one of the wayang beber types, an Indonesian traditional picture. We describe the programming approach to generate a pattern of wayang beber Pacitan character's cloth. This cloth has three typical patterns: a line pattern, color pattern, and wavy shape pattern. We create a new shader algorithm based on the Sor's shader algorithm, s and t coloration, and surface displacement to generate these three types of patterns.


The Caltech Faint Galaxy Redshift Survey has collected ∼2000 spectra taken with multi-slit masks using the Low Resolution Imaging Spectrograph at the Keck Observatory (Oke et al. 1995) in two widely separated fields on the sky, each ∼1 x 1 deg 2. Most of these objects are faint field galaxies; about 10% are Galactic stars and about 1% are broad-lined AGNs. I summarize the small scale clustering of this sample as well as the evidence in support of large scale structure.


Predicting the attitudes of a powerful out-group can influence attitude strength and the perceived status of in-group members. American farmers indicated their own attitude positions on eight issues relevant to conflict with the Environmental Protection Agency (EPA), and then estimated the positions either of their in-group, the EPA, a control out-group, or participated in a no-estimation control condition. The estimation of attitude disagreement with EPA agents elicited negative thoughts about their power and control which mediated a decrease in self-certainty. Assumed attitude contrast also diminished the perceived status of farmers. Discussion focuses on relational and instrumental sub-group connections.


Many foods contain native or modified starch types. As is known from practice, starch residues tend to adhere severely to solid surfaces. By means of a special testing method that has been developed for this purpose the removal of native and modified starch types from glass surfaces has been tested under standardized cleaning conditions. As the results show, the behaviour of a starch film in the cleaning process significantly depends on the type of the soiling starch. The specific properties of the applied starch such as gelatinization temperature, swelling power, solubility and chemical composition are important factors influencing the success of the cleaning process: cereal starch of wheat, corn or rice cause much higher residues on cleaned glass surfaces than potato starch or chemically modified starch types. It is assumed that the cleaning solution must at least reach the gelatinization temperature in order to minimize the residues on glass because a sufficient swelling has to precede the removal of the starch film. Water soluble additives - saccharose or xanthan-enhance the removal of starch. A similar effect can be obtained if skim milk or hard tap water is used for the preparation of the starch suspensions instead of deionized water. The cleaning tests proved that pure starch suspensions of cereal starches represent heavily adhering soils. Potato starches and mixtures of starch with more water soluble additives are more easy to clean. For the evaluation of cleaning tests it seems therefore advisable to use films of corn starch without additives.


Demand response on the residential market is becoming a solution to adapt customer consumption to the offer available and therefore lower the electricity peak prices. Tariff incentives and direct load control of residential air-conditioners and electric heaters are flexible solutions to reduce the peak demand. To include residential demand response resources in planning operators, quantifying the demand reduction is becoming a major issue for all electrical stakeholders. Current methods are based on day or weather matching, regressions and control group approaches. In general, methods using available data from a control group give more accurate results. With the introduction of smart meters, the electric utilities generate a large amount of quality data, available almost in real time. In this paper, we suggest using these available residential load curves to select a control group based on individual load curves. One of the advantages of our method is that the selected control group could adapt at anytime to the number of individuals belonging to the demand reduction program, as this number evolves with customers entering and leaving the program. Constrained regression methods and an algorithm are developed and evaluated on real data, providing a reliable solution for an operational use.


Objective To observe the clinical efficacy of integrated Chinese and western medicine in liver injury caused by chemotherapy in patients with breast cancer.Methods Thirty patients were treated by soothing the liver and invigorating the spleen,clearing away heat to remove toxin,disinhibiting dampness to resolve blood stasis methods and western medicine diammonium glycyrrhizinate,with the course of 14 days.The changes of clinical symptoms and liver function were observed.Results The total effective rate was 93.3%,and the levels of AST and ALT were decreased significantly(P0.05).Conclusion Integrated Chinese and western medicine has positive effect on liver damage caused by chemotherapy in patients with postoperative breast cancer.


FIELD: machine building. SUBSTANCE: invention refers to system of connection for detached connection of axis-symmetrical parts, particularly parts of reel for winding bundles of items. The system of connection consists of circular surfaces on facing each other front surfaces of connected parts of the reel. Also the system of connection consists of locking lugs projecting from at least one circular surface in the direction of another circular surface and of stop recesses in one circular surface or in both circular surfaces to receive the locking lugs and to connect parts of the reel with a bayonet lock by means of mutual rotation. The connecting system contains spring catches made coaxially with corresponding stop recesses; the catches engage the locking lugs behind them in locked position and prevent connected parts unscrewing into a detached position. The system of connection contains sliding push-down elements in one of their position releasing the spring catches from engagement with the locking lugs. The push-down elements of the connecting system are made on a ring rotating on a back side of circular surfaces. EFFECT: simplified connection of reel parts and increased protection against occasional detachment of reel parts. 4 cl, 3 dwg


The purpose of the present article is to prove that womwn practiced the writing of literature since the 19 th century in the region of the Valle del Cauca. From the starting point of a critical approach to the novels Alfonso. Cuadros de costumbres (Mercedes Hurtado de Alvarez) and Misterios de la vida (Mercedes Gomez Victoria), a search for the creative itinerary of these two narrators and the forms of writing that give an account of the construction of identities in a society crossed by wars, coldness and abandonment.


In this work we define an universal arithmetical algorithm, by means of the standard quantum mechanical formalism, called universal qm-arithmetical algorithm. By universal qm-arithmetical algorithm any decidable arithmetical formula (operation) can be decided (realized, calculated. Arithmetic defined by universal qm-arithmetical algorithm called qm-arithmetic one-to-one corresponds to decidable part of the usual arithmetic. We prove that in the qm-arithmetic the undecidable arithmetical formulas (operations) cannot exist (cannot be consistently defined). Or, we prove that qm-arithmetic has no undecidable parts. In this way we show that qm-arithmetic, that holds neither Church's undecidability nor Godel's incompleteness, is decidable and complete. Finally, we suggest that problems of the foundation of the arithmetic, can be solved by qm-arithmetic.


Does IBD Affect Fertility in Men? The fertility of men with inflammatory bowel disease (IBD) has not been studied prospectively in much detail. It seems to be normal in the vast majority of cases; however, it is significantly decreased during treatment with sulfasalazine, may be slightly reduced in patients with Crohn's disease (CD), and there is a (low) risk of sexual dysfunction after restorative proctectomy. Some series from Europe and the US have suggested that men with CD have slightly fewer children than healthy controls,1,2 independently of any treatment with sulfasalazine. The evidence, however, is presently sparse and the etiology unclear. Ill health and poor nutrition have been suspected and 1 study suggested that zinc deficiency may be involved.3 There is strong evidence that men and male animals treated with sulfasalazine have decreased fertility. More than 80% of men receiving this drug have semen abnormalities consisting of oligospermia, abnormal forms, and impaired motility.4,5 This effect has been shown to recover within 3 months after sulfasalazine cessation and to recur after sulfasalazine reintroduction.4,5 The sulfapyridine moiety of the drug is responsible for this adverse event and both experimental and postmarketing studies have shown that mesalazine (5-ASA) does not impair fertility in men nor in animals.4,5 Several case reports and small series have shown recovery of the sperm characteristics as well as a return to fertility after about 3 months when sulfasalazine was replaced with 5-ASA.4,5 Azathioprine and 6-mercaptopurine (6-MP) do not induce significant reduction in semen quality or male fertility.6 A recent study also showed that long-term 6-MP treatment in male mice did not impair sperm production and sperm morphology; however, a significantly high rate of embryonic resorption indicated occult sperm damage.7 A recent pilot study suggested that infliximab therapy may decrease sperm motility and the number of normal oval forms. Only 10 men were studied and on a short-term basis. Whether these findings will be confirmed in larger series and will translate into impaired fertility is an area for further study.8 There is a slight risk of alteration of sexual functions after restorative proctocolectomy and ileoanal anastomosis (IAA). Retrograde ejaculation has been reported in about 2%9,10 and erectile function problems in 1%–14.6%.9,10


1. The dominant eigenvalue of the population projection matrix provides the asymptotic growth rate of a population. Perturbation analysis examines how changes in vital rates and transitions affect this growth rate. The standard approach to evaluating the effect of a perturbation uses sensitivities and elasticities to provide a linear approximation.


Abstract China is now South Africa's significant trading partner, so it is important to examine how the resulting trade benefits compare with those from South Africa's long standing traditional trading partners. South Africa's trade with its long standing traditional partners and with China is examined by analysing the factor intensities of goods traded; trade intensity with each country; ease of market access of its products; and intra-industry trade opportunities. Results show that South Africa continues to benefit more from trade with its long standing trading partners than it does with China. Trade with China merely provides South Africa a market mainly for non-fuel primary commodities, while the traditional trading partners provide markets for both low value and high value added products and opportunities for intra-industry trade. This is essential for innovation and technology spillovers both of which are essential to help South Africa to develop its manufacturing base further.


If we aren't diligent about tending our hearts, sin has a way of creeping in and multiplying. Ordained Minister Aly Salz muses on gardening, and how we need God to be our Master Gardener, to help us pull weeds and tend seeds to grow and flourish.


We analyse the geometric instability of embeddings produced by graph neural networks (GNNs). Existing methods are only applicable for small graphs and lack context in the graph domain. We propose a simple, efficient and graph-native Graph Gram Index (GGI) to measure such instability which is invariant to permutation, orthogonal transformation, translation and order of evaluation. This allows us to study the varying instability behaviour of GNN embeddings on large graphs for both node classification and link prediction.


In this paper, digital modulation performance of two‐section, multiple quantum well gain‐levered laser diode in a fiber optic link is analyzed. This study involves numerical simulation of gain‐levered laser diode along with single‐mode fiber for evaluating gigabit rate digital transmission. The optical link performance is analyzed by evaluating the eye diagram, extinction ratio, and quality factor for different bit rates, modulation current, and fiber lengths. The results are compared with unlevered or normal laser diode–based fiber optic link with similar operating conditions. A 12‐dB improvement in extinction ratio is obtained for gain‐levered laser diode when the longer section and shorter section currents are kept as 30 and 0.5 mA, respectively. The Q parameter is found to increase with increasing modulation current in the gain‐levered case, and a maximum Q factor of 11 is obtained for a modulation current of 5 mA. The Q value is improved by a factor of 8 and 5 at 1‐ Gbps and 10‐Gbps data rates, respectively, under gain‐levered condition, when compared to normal laser diode–based link.


An ability of reinforced concrete slabs to distribute concentrated load in transverse direction is an important property for their verification. Several methods for the assessment of transverse distribution (effective width) were proposed but they were not incorporated in the current standards. This paper deals with an experimental analysis of the effective width for shear verification of slabs subjected to concentrated load. Shear resistance of the slab specimens subjected to concentrated load obtained from tests has been compared with resistance of the slab strips loaded by uniform shear. Based on this check, the effective width has been evaluated. Experimental results were also compared with results of models introduced in relevant standards.


Malignant cells constitutively express Natural killer group 2, member D (NKG2D) or DNAX Accessory Molecule-1 (DNAM-1) ligands, yet they are often unable to trigger a robust cytotoxic cell response. It may be therapeutically useful to implement strategies aimed at increasing the density of NKG2D and DNAM-1 ligands on the surface of cancer cells, endowing them with the capacity to activate potent antitumor natural killer-cell responses.


adar data contain phase errors whose sources include uncompensated platform motion and transmitter and receiver phase errors. Achieving theoretical resolution from a pulse compression system requires a method to minimize those phase errors. This article discusses a method of estimating and correcting phase errors in synthetic aperture radar data. The method requires that one or more stationary point targets be included in the data. The phase history of each reference target is estimated for the period in which the target is in the view of the radar. The phase error, computed as the deviation from the theoretical phase function, is estimated and removed from the raw data. Unfortunately, conventional continuous phase measurement requires high signal-to-noise ratio. To increase the effective signal-to-noise ratio of the raw reference target data, the targets are extracted after matched filtering, and the resulting data are inverse matched filtered. In one test data set, this phase correction method improved the synthetic aperture radar image resolution by 50%. (


Geographic registration (geo-registration) is a crucial foundation for augmented reality (AR) map applications. However, existing methods encounter difficulties in aligning spatial data with the ground surface in complex outdoor scenarios. These challenges make it difficult to accurately estimate the geographic north orientation. Consequently, the accuracy and robustness of these methods are limited. To overcome these challenges, this paper proposes a rotation-invariant estimation method for high-precision geo-registration in AR maps. The method introduces several innovations. Firstly, it improves the accuracy of generating heading data from low-cost hardware by utilizing Real-Time Kinematic GPS and visual-inertial fusion. This improvement contributes to the increased stability and precise alignment of virtual objects in complex environments. Secondly, a fusion method combines the true-north direction vector and the gravity vector to eliminate alignment errors between geospatial data and the ground surface. Lastly, the proposed method dynamically combines the initial attitude relative to the geographic north direction with the motion-estimated attitude using visual-inertial fusion. This approach significantly reduces the requirements on sensor hardware quality and calibration accuracy, making it applicable to various AR precision systems such as smartphones and augmented reality glasses. The experimental results show that this method achieves AR geo-registration accuracy at the 0.1-degree level, which is about twice as high as traditional AR geo-registration methods. Additionally, it exhibits better robustness for AR applications in complex scenarios.


The reverse engineering is considered one means of manufacture.It can measure the part of the automotive panel and reconstruct its model.The panel point cloud data were got by the ATOS laser scan instrument using the reverse engineering technology and were processed in Imageware software.The 3D model of panel was set up in UG by the curve and surface modeling and 3D model reconstructing,the 3D model precision was inspected.


The third generation of cultured bovine fibroblasts for the study, such as cell growth curve, morphology, vitality, cell cycle, and the expression of Oct4 and Cdx2. The bovine fibroblast began to appear abnormal morphology and increase the number of dead cells when the concentration of TSA was higher than 50 nmol · L- 1. The result of MTT showed that the viability of bovine fibroblast was inhibited significantly after treatment by 50 nmol · L- 1TSA for 24 h. Bovine fibroblast chromosomal composition was affected by HDACi. The diploid composition of the cells decreased significantly treated by 50 nmol· L- 1TSA for 48 h. The cell cycle was detected by flow cytometry showed that up to 60% of cells were arrested in G0/G1 phase treated by 50 nmol· L-1TSA for 24 h. Real-Time PCR results showed that compared with the control group, after TSA treatment, the expression of Oct4 increased significantly, while the expression level of Cdx2 gene decreased. HDACi treated bovine fibroblast cells may benefit the epigenetic reprogramming and the cloned embryos development when it was used as donor cells in somatic cell nuclear transfer.


Neuroinflammation has been proposed as part of the pathogenesis of post‐concussion symptoms (PCS), but the inflammatory response of the human brain to mild traumatic brain injury (mTBI) remains unknown. We hypothesized that a neuroinflammatory response is present in mTBI at 1–2 weeks post‐injury and persists in patients with PCS.


[1] Recent observational studies have shown that the southern center of the summer North Atlantic Oscillation (SNAO) shifted eastward after the late 1970s. In this study, this phenomenon and its causes are further explored. It is found that the decadal spatial shift of the SNAO southern center is related to the decadal variability of the tropical Atlantic sea surface temperature (TASST). In the past half century, the TASST experienced an abrupt change around the late 1970s, with a rapid warming in the recent 2 decades. Thus in the period after the late 1970s when the TASST is relatively warmer, the TASST released more energy into the atmosphere, then stimulated strong convection over the tropical Atlantic, and further excited anomalous wave-like patterns. This strengthened the circulation in the region of the Mediterranean Sea, namely the east part of the SNAO southern center, consequently leading to an eastward shift of the SNAO southern center. Meanwhile, in the period before the late 1970s when the TASST is relatively cooler, the TASST released less energy into the atmosphere, so its impact on the overlying atmosphere was significantly weakened and confined to the lower-level atmosphere of the tropical Atlantic. Thus the TASST possibly did not influence the variability of the SNAO southern center, and the SNAO pattern exhibited a traditional distribution with two centers over the North Atlantic.


The invention relates to a moulding, which can be permeated by a fluid in at least one flow direction. The moulding comprises a plurality of parallel successive layers. Each layer has recesses and at least one area that is bonded to a subsequent or preceding layer. Each recess of a layer overlaps at least one region of the recess of a subsequent or preceding layer. The layers as a whole thereby form step-like ridges in the moulding. The moulding comprise at least two such ridges. The invention further relates to production methods for producing said mouldings, and to the use of said mouldings and reactors that contain said mouldings.


The invention discloses a heat-convertible heat pipe exchanger and a working method of the heat-convertible heat pipe exchanger. Tail gas arrives at a gas chamber through a gas inlet pipe. Working media in evaporation sections of heat pipes absorb heat to vaporize, flow to condensation sections under the action of steam pressure and carry the heat to the condensation sections. Working medium steam in the condensation sections cools, is liquefied, releases heat and transfers the heat to heating media, so the temperature of the heating media rises. The working media flow back to the evaporation sections to participate in a next heat cycle under the action of capillary force of liquid absorption cores of the heat pipes. The heating media at a rising temperature are discharged from a liquid drain pipe and subjected to heat transfer with a generator, the temperature of the heating media is lowered, and then the heating media flow into a liquid collection tank through a liquid inlet pipe and receive the heat of the tail gas cyclically. By the adoption of the heat-convertible heat pipe exchanger, refrigeration is not needed or a refrigeration load is small, so the contact area between the evaporation sections of the heat pipes and the gas chamber is reduced; the part needing heat requires much heat, so the contact area between the evaporation sections of the heat pipes and the gas chamber is increased. The heat exchange amount of the heat-convertible heat pipe exchanger can be controlled, and the heat-convertible heat pipe exchanger can meet the requirement of the part needing heat for energy supply on different conditions and has very high safety and flexibility.


The topic of this thesis are witch-hunts in Germany, where they took place especially between 1560 and 1650. First, the author turns to the power relations in the Catholic Church which led in the massive appearance of heretic groups around the year 1000. As example she mentions the Cathars and the actions the Church took against them. Further, she gives attention to the birth of Inquisition, its objective and the extension of its powers through papal bulls. After that, she turns to the Templars and their downfall {--} here, the French king cooperated with the Inquisition. In the next chapter, the author shows how the trials against heretics changed into witch-hunts. She names the possible circumstances under which this change took place. In the following part of the thesis, the author turns to the witch-hunts in Germany, their beginning and termination in 1775. In the last part she names possible reasons for the beginning and the termination of witch-hunts.


A s a result of Public Law 94142, the Individuals with Disabilities Education Act (formerly known as the Education for All Handicapped Children Act of 1975), many students with hearing impairments are being educated in regular education settings with their hearing peers. Data from the Fifteenth Annual Report to Congress on the Implementation of the Individuals with Disabilities Education Act (U.S. Department of Education, 1993) indicate that approximately 47% of students with hearing impairments are taught in inclusive settings. These students need a variety of services to enhance their academic performance and social adjustment in such settings. One essential service that many students with hearing impairml?nts attending regular classes may need is an educational interpreter (Commission on the Education of the Deaf, 1988; Rittenhouse, Rahn, & Morreau, 1989). The


The invention relates to fresh water cultivation, in particular to a fish pond sprinkling irrigation aerator. The main technical point is as following: the length of a water inlet pipe is 80 percent to 90 percent of that of a pond bottom, the wall of the water inlet pipe under the water is provided with small holes with diameters from 8 mm to 12 mm, the densities of a front section and a middle section of the water inlet pipe, which are close to a water pump are smaller than the density of a back section, the areas of the small holes account for 10 percent of the wall area of the front section of the water inlet pipe, 20 percent of the wall area of the middle section of the water inlet pipe and 30 percent of the wall area of the rear section of the water inlet pipe , a filtration net is wrapped on the surface of the water inlet pipe, and the mesh of the filtration net is from 80 to 100. The water inlet pipe is fixedly connected with an upright pipe, the end part of the upright pipe isconnected with a spray head, and the distance between the spray head and the water surface of the pond is 40 cm to 60 cm. the height between the water inlet pipe and the pond bottom surface is 55 cm to 65 cm. An oxygen sensor is arranged in the middle of the water surface of the pond. The invention combines the sprinkling irrigation technology of plant production irrigation and freshwater cultivation into a whole, has the advantages of low invest, good aeration effect, no influence on the clarity of water, low noise and the like, and creates an excellent growth environment for the growth of various animals cultivated in fresh water.


Traditional utilisation of Garcinia lucida and Garcinia kola (Clusiaceae) in Cameroon. Garcinia lucida and Garcinia kola (Clusiaceae) are common well-known forest species among local po- pulation in Cameroon due to their various medicinal properties. A study of the traditional uses and the harvesting practices of these two species permits to draw together their medicinal, social and economic potentials in order to promote their utilisation and long-term exploitation. Traditional medicines and foods are the main important use categories. The seeds and the bark are the most commonly used parts of these plant species. The seeds are generally gathered under the crown of reproductive trees while the extraction of bark almost always involved ringbarking trees, the extraction of root involved logging of trees. The density of G. lucida varies from 17 to 314 stems per hectare. The average number of G. kola trees is 0.4 stems per hectare. The proportion of trees dying after debarking ranked between 5 and 43% according to the exploited stands of G. lucida. The proportion of debarked and logged trees for G. kola was estimated about 43%. The size-class distribution exhibited by these two species shows a selective exploitation of the largest trees. The quantity of G. lucidafresh bark harvested was estimated at 15 kg per day and per collector. These results indicate a high exploitation pressure using destructive harvesting techniques which could lead to the resource depletion in the future.


Background: Tissue Doppler imaging (TDI) has been quite useful in determining the mechanical properties of right ventricular (RV) function in patients with pulmonary hypertension (PH). However, to what extent these mechanical properties are expected to identify RV dysfunction in PH patients is less clear. Methods: Our echocardiography database was queried for patients with PH of different etiologies (111 patients, age 55 ± 14 years, mean pulmonary artery pressure 63 ± 24 mmHg) who had undergone TDI analysis and compared to similarly collected data from a group of healthy individuals (35 patients, mean age 45 ± 15 years, mean pulmonary artery pressure 27 ± 5 mmHg). Results: ROC analysis demonstrated that a mechanical delay between the RVFw and IS > 25 ms detects PH while a delay > 37 ms detects abnormal RV performance. Peak RV strain < −20% identifies PH greater than 40 mmHg and a reduced RV systolic function. However, on a stepwise multiple regression analysis model RV dyssynchrony was the most significant predictor of PH (r = 0.515; P = 0.0003) over peak longitudinal RV strain (r = 0.553; P = 0.02) and RVFAC (r =−0.603; P = 0.01). Peak longitudinal strain was the most significant predictor (r =−0.722; P < 0.0001) of an abnormal RVFAC over PH (r =−0.603; P = 0.004) and RV dyssynchrony (r =−0.471; P = 0.01). Conclusion: A normal range of RV mechanical variables in PH patients are provided that can be applied in the assessment of RV performance.


Objective:To observe the quantitative and functional changes of CD4+CD25+ regulatory T cells(CD4+CD25+Treg)in experimental anti-phospholipid syndrome(EAPS)mice fed with recombinant human β2-glycoprotein 1(rhβ2-GP1).Methods:EAPS model was established by immunizing BALB/c mice with rhβ2-GP1.In tolerized groups,EAPS mice were fed with rhβ2-GP1 10 days before immunization.Anti-β2-glycoprotein 1(anti-β2GPI),anticardiolipin(aCL)titers in the sera,rate of the fetal resorptions,activated partial thromboplastin time(aPTT)and platelet counts were assayed after 12 weeks.Percentage of CD4+CD25+Treg in peripheral blood mononuclear cells in mice from each groups were determined by flow cytometry,the expressions levels of Foxp3 mRNA were detected by RT-PCR.Results:In tolerized mice anti-β2GPI and aCL Abs decreased significantly(P0.05),resorption percentage decreased(P0.05),aPTT shortened(P0.05),and platelet counts elevated(P0.05).The expressing levels of Foxp3 mRNA in the tolerized group were higher than those of control group(P0.05)on the fourth,eighth,twelfth weeks after immunization(P0.05),but they began to decrease after twelfth week and there were no significant differences on twentieth weeks between tolerized groups and control group(P0.05).The expressing levels of Foxp3 mRNA in the tolerized group were paralleled to model group on fouth week(P0.05)and the latter began to decrease after eighth week and were lower than those of control group significantly after twelfth week(P0.05).The percentage of CD4+CD25+Treg cells from PBMC in tolerized group were paralleled to those of control group during oral tolerance induction(P0.05).Conclusion:CD4+CD25+Treg cells play roles in the induction of oral tolerance in EAPS.


An expert network administrator is not always stationed as disasters happen. In that case, it is desirable that a novice administrator is capable of taking part in network recovery operations as well. In this paper, aknowledge-based network management system in emergency situations is presented. We use the Active Information Resource based Network Management System (AIR-NMS) to relieve the human administrator from parts of her management tasks and present an interface that remotely can control this management system. The effectiveness of the system is demonstrated by experiments using a prototype system.


Summary. Although the tendency for surge peaks in the Thames to occur on rising tide has been recognized for some time, no satisfactory physical explanation has been presented. The phenomenon almost certainly results from non-linear interaction between tide and surge and it is the mechanism of this interaction which is examined in the present study.

A statistical analysis of surges recorded at 10 ports located along the east coast of Britain demonstrated the development of interaction as surges propagate southwards. This analysis showed that surges tend to develop a peak on the rising tide in the Thames irrespective of the phase relationship between tide and surge in the northern North Sea.

A one-dimensional model of the River Thames was used to examine how surge-tide interaction varied for surges of differing types. In order to identify the mechanics of interaction, a new modelling technique was developed involving two models, one of tidal propagation and one of surge propagation, operated simultaneously with cross-linkages in the form of perturbation terms providing the effects of interaction. By this means it was shown that quadratic friction is the dominant interaction mechanism in the Thames.


A.I. Mal'tsev [6] proposed the problem to obtain the description of iterative algebras of functions in propositional logics. From functional point of view a special interest represent the separation and description of maximal iterative algebras. L. Esakia and V. Meshi [1] and independly L.Maksimova [5] discovered the existence of pre-tabular modal logic EM4. It is approximated by the logics of a series of topological Boolean algebras ∆i(i = 1, 2, . . . ) of order 2i with 3 open elements. In this work, for first time, a maximal subalgebra of iterative algebra of functions of topological Boolean algebra of order 16 with one open atom is built.


. The paper investigates some properties of recently defined forward and backward shifts of vector fields. The main purpose of the paper is to show that the forward and backward shifts of vector fields commute with the Lie bracket operator and with some commonly used system transformations. The latter include, for example, classical and parametrized state transformations as well as static and dynamic state feedbacks. These properties become important when studying control problems involving such transformations.


A study of the adsorption of allene on VCl3, TiCl3 Type 1.1, and TiCl3 Type H catalysts has been made. In the absence of cocatalyst, allene adsorption is observed and in the case of the TiCl3 Type 1.1 catalyst rapid oligomerization of allene occurs. Activation with Al(C2H5)3 leads to a slow consumption of allene with VCl3 and TiCl3 Type H, but shows no distinct change for the TiCl3 Type 1.1 catalyst. The amount of "adsorbed" allene is generally higher than the number of active sites and this is attributed to adsorption on sites which are inactive in polymerization and to consumption of allene through side-reactions.


Aim:  To determine the feasibility of identifying the main trunk of the uterine artery by tracing its superior branch with a laparoscopic technique.


Stitching image altering detecting method disclosed by the invention based on color filter array characteristic, comprising the following steps: image to be detected is divided into the pretreatment of multiple images block by step 1;Step 2 estimates original image mode;Step 3 carries out tampering location detection using edge detection operator.The variation or otherness feature of periodical associative mode between the image pixel that stitching image altering detecting method based on color filter array characteristic of the invention utilizes color filter array interpolation introduced, carry out stitching image tampering detection, it can not only detect whether image is spliced and distort, and be able to detect the position for being tampered region;In the tampering location stage due to having introduced Canny operator, make algorithm tampering location precision with higher, it can the edge for being tampered region is precisely located out, and false edge of effectively having drawn up;To image processing operations such as JPEG compression, different types of filtering plus processing etc. of making an uproar that content is kept, there is preferable robustness.


Results of synchrotron based high pressure x ray diffraction measurements on Heuslar alloys Ni2MnGa and Co2FeSi are reported up to 30.6 and 24.6 GPa respectively. Pressure volume data for Ni2MnGa shows normal compressibility behaviour up to 30.6 GPa with the value of bulk modulus Bo and its pressure derivative B′ as 130 GPa and 4.97 respectively. In case of Co2FeSi, the P‐V data shows normal behaviour upto 5 Gpa and hereafter linear P‐V relation. The estimated ambient pressure compressibility based on data up to 5 GPa is 267 GPa (with B′ = 4). The fit to linear P‐V data above 5 GPa yields a compressibility of 279.5.


Purpose – The purpose of this paper is to investigate university faculty perceptions and practices of using Wikipedia as a teaching resource. Design/methodology/approach – This study is based on a large survey to all faculty members in two large public universities. A total of 913 valid responses were collected through an online questionnaire with 9 control variables and 41 Likert-scaled questions. Findings – The results do not support an overwhelming sceptical attitude among faculty towards Wikipedia. The overall quality of Wikipedia articles is highly valued and most faculty are regular users, just as students are. Though most faculty show a positive view on the teaching usefulness of Wikipedia, few of them actually use it for teaching purposes. A certain conflict has been detected between standard academic procedures of knowledge building and the open collaborative model on which Wikipedia rests. In the end, two important factors play a role in shaping faculty views: their colleagues' perceived opinion...


Analysis of pollen and plant and insect macrofossils from 9400-yr-old fluvial terrace deposits along the Ikpikpuk River on the Arctic Slope of Alaska permit reconstruction of the diversity of habitats present at that time, as well as an assessment of surface moisture conditions and summer temperatures relative to those of today. Consideration of the modern ecological requirements for the total fossil flora and fauna shows that the variety of habitats was similar to the total variety seen today. However, the beetle fauna is dominated by species indicative of dry, open grasslands, suggesting that dry, well-drained habitats were more widespread than now. Warmer summer temperatures are indicated by extralimital taxa including Populus balsamifera and seven beetle species that reach their present northern limits in the boreal forest zone of north-central Alaska and adjacent Canada. Consideration of the modern climatic tolerances of the beetle taxa suggests that early Holocene mean July temperatures at the fossil


In this work, some results obtained by Trabucho and Viano for the shear stress distribution in beam cross sections using asymptotic expansions of the three-dimensional elasticity
equations are compared with those calculated by the classical formulae of the Strength of Materials. We use beams with rectangular and circular cross section to compare the degree of accuracy reached by each method.


This review will give a brief introduction to the growth and characterization methods of both binary and ternary compounds, in particular those exhibiting one-dimensionality, of the family to orient the readers about the material system to be discussed. A section will deal with the size and shape selection in group III nitride nanomaterials with a stress on intriguing morphologies such as nanowires, nanotips, and nanobelts. Complex structures, such as hierarchical and core-shell structures, will be introduced. Optical, electrical, and mechanical property, such as hardness, will be discussed in a greater detail, distinguishing the bulk from the nano wherever possible. Available models of electrical conduction and photoconduction in nanomaterials and their dependence on the actual size of the objects will be presented and compared. Optical properties of ensemble and single nanostructures, wherever possible, will be addressed in detail. The section on application will focus mainly on the sensor applications, including chemical sensors, gas sensors, and biosensors, with a thrust on DNA sensing. Because popular applications such as light-emitting diodes (LEDs) and field effect transistors (FETs) have already been reviewed extensively, only major contributions to this field—for example, nano-LEDs—will be discussed. Some recent advances in the group III-nitride materials family will be presented that will indicate future directions of research in this area.


Identifying Drug-Target Interactions (DTIs) is a major challenge for
current drug discovery and drug repositioning. Compared to traditional experimental approaches,
in silico methods are fast and inexpensive. With the increase in open-access experimental data,
numerous computational methods have been applied to predict DTIs.

In this study, we propose an end-to-end learning model of Factorization Machine and
Deep Neural Network (FM-DNN), which emphasizes both low-order (first or second order) and
high-order (higher than second order) feature interactions without any feature engineering other
than raw features. This approach combines the power of FM and DNN learning for feature
learning in a new neural network architecture.

The experimental DTI basic features include drug characteristics (609), target
characteristics (1819), plus drug ID, target ID, total 2430. We compare 8 models such as SVM,
GBDT, WIDE-DEEP etc, the FM-DNN algorithm model obtains the best results of AUC(0.8866)
and AUPR(0.8281).

Feature engineering is a job that requires expert knowledge, it is often difficult and
time-consuming to achieve good results. FM-DNN can auto learn a lower-order expression by FM
and a high-order expression by DNN.FM-DNN model has outstanding advantages over other
commonly used models.


In the base of concept attention , the author analyses the multiple elements which affect the range of basketball referee when they are on duty .


Tobacco use remains the leading cause of premature death and a number of serious illnesses in the U.S. Despite the significant decrease of the number of smokers over the last 50 years not least due to the implementation of a variety of tobacco control strategies, the problem of tobacco use is still far from being solved. The numbers of smokers are stagnating, in particular among low socio-economic status population. Based on insights from behavioral economics, this article develops a new regulatory model against smoking initiation among adolescents as well as for smoking cessation among adult smokers. By appealing to well-known deficiencies in human decision-making, such as overweighting of small probabilities, loss and regret aversion or present bias, the article suggests providing positive economic incentives in form of weekly lotteries and a raising credit balance that can only be accessed after a specific period of non-smoking in order to reduce tobacco use.


Two new frequency-domain conditions for stability analysis of the feedback interconnection between a linear time-invariant (LTI) system and a sector-bounded hybrid integrator are presented. Compared to existing results, the conditions exploit more knowledge regarding the hybrid integrator's switching strategy, and guarantee the existence of a quadratic Lyapunov function that does not need to be positive within the full state-space. The conditions can be verified graphically on the basis of frequency response function data in a manner that is comparable to the classical Popov plot, making these tools valuable in practice.


SUMMARY The article discusses the concept, history and development of eSports, its legal nature and types of intellectual property rights arising in this field. Researched problems of legal regulation of eSports and the protection of intellectual property rights are investigated.