This study sought to analyse the applicability of risk based internal auditing in Crowne Plaza Monomotapa Hotel. The literature from different authors was reviewed concerning the research topic. The main goal of this research was to analyse if risk based internal auditing can be applied in the hotel, how can it be implemented and is there adequate staff and resources for it to be implemented. The researcher used a descriptive design as a research design. The researcher used stratified random sampling to determine the population and the sample size. Questionnaires and interviews were the research instruments used to gather data for the research. A sample size of 20 respondents was used in carrying out the research study; the management, internal auditors and staff of the hotel were included in the sample. The data was collected and analysed using tables, graphs and pie charts. Basing on the research Crowne Plaza Monomotapa Hotel cannot implement risk based internal auditing since there is no risk management framework though the hotel has other necessary resources. The research recommended that the organization board should devise a strategy that will establish the a risk management framework which will enable he hotel to implement risk based internal auditing that can mitigate the risks being faced by the hotel.


Objective To develop a high performance LC-MS/MS method for the determination of N3 in rhesus plasma.Methods The analysis was performed on a BioBasic C 18 column(100 mm × 2.1 mm,5 μm) with acetonitrile-water(containing 0.2% formic acid)(55 ∶ 45,V ∶ V) as the mobile phase.A mass spectrometer equipped with electrospray ionization(ESI) source was used as the detector and operated in the positive ion mode.The selected reactions monitoring(SRM) mode with the transitions of m / z 681.3 /402.2 was used to quantify N3.Results N3 in rhesus plasma was extracted by protein precipitation with acetonitrile,and the supernatant was injected into the LC-MS / MS system for determination.Under optimized LC-MS / MS conditions,the standard curve was linear over the concentration range of 20-2500 μg·L-1for N3.The accuracy(relative error,RE) of this method ranged from-12.9% to 2.9%.The intra-day and inter-day precision(relative standard deviation,RSD) was less than 7.5%(n = 6) and 7.8%(n = 18),respectively.The recovery of the method for N3 of 50,1000 and 2000 μg·L-1in rhesus plasma was 75.0%,76.9% and 79.5%,respectively.Conclusion The established method is shown to be sensitive,accurate,quick and effective for investigation of N3 pharmacokinetics in rhesus.


Background: A short columella is one of the most severe problems in bilateral cleft lip and nose deformity. In particular, with tissue insufficiency or scar contracture on the upper lip, it is very hard to achieve a good nasal profile with conventional methods. Methods: One hundred thirty-seven patients with a short columella were operated on from February of 1987 to December of 2008. The average age at operation was 7.3 years. The conchal cartilage was harvested. The preauricular or postauricular skin-subcutaneous fat composite tissue was harvested. Through a transcolumellar incision, the conchal cartilage was inset and the defect was covered with skin-fat composite tissue. The serial nasal profiles were evaluated before and after surgery. Also, the postoperative nasal profiles were compared with normal profiles. The postoperative color difference with surrounding skin was measured by the L*a*b* photographic analysis method. Results: The mean height and width of skin-subcutaneous fat composite tissue were 9.81 and 22.14 mm, respectively. The preoperative and postoperative measuring for columella height was 5.1 ± 1.1 mm and 14.2 ± 1.5 mm. The columella-lip angle was 120.30 ± 12.97 preoperatively degrees and 98.76 ± 10.98 degrees postoperatively, whereas the angle of columellar-alar triangle was 111.56 ± 11.39 degrees and 97.91 ± 11.49 degrees, respectively. None of the postoperative profiles were different from those of normal Korean people of the same age except in the 0- to 6-year-old group (p < 0.05). The color match was best with preauricular composite tissue. Complications included total necrosis in three cases and partial necrosis in 12 cases that were treated conservatively. Conclusion: Elongating columella using a composite graft can be a satisfying alternative, especially for a severe short columella with upper lip tissue deficiency.


Crime scene artifacts include a handgun, revolver, or gun are utilised in most criminal crimes. A human must intervene in the surveillance and control system to discover such illegal activity. The purpose of this study is to create an automated, real-time object detection system for use with surveillance cameras at crime scenes. The intention is to warn security personnel of potentially dangerous situations. The proposed Fully connected Convolutional neural networks (CNNs) combined with Edge Computing so it is called hybrid system, and faster region-convolutional neural networks (faster R-CNNs), and regression are all examples of deep learning algorithms. Among the most promising approaches for detecting objects now in use are linear-based detectors YoloV7. Real-time detection requires a faster detection speed than region-based algorithms can provide. On the other hand, real-time detection may be achieved using regression-linear-based detectors such as YoloV7. In this research, YoloV7 was used to identify crime objects quickly. Crime object, and then Fully Connected CNN was used to improve detection accuracy. The system is trained and tested using a crime object dataset consisting of 5,660 images of weapons and anomaly action that are both publicly and privately accessible, with an 80-20 split, and then assessed using live security camera footage. In addition to its 92% accuracy, 95% precision, 88% recall, and an F1 score of 88.5%. The resultant findings validate the use of the suggested hybrid system for real-time monitoring by indicating the presence of a suspect carrier in an area under observation.


For over a decade, the Mexican government has invested itself in a "frontal attack" on drug trafficking organizations with catastrophic results. Little to nothing has been gained in limiting drug production, use, or trafficking, while violence has skyrocketed and major institutional and human rights crises have evolved. Through a multidisciplinary approach—which includes history, sociology, policy analysis, and constitutional doctrine—this essay evaluates drug prohibition in Mexico: its history, key components and documented results. It concludes that prohibition, as a guiding principle of drug policy, can and should be abandoned for all drugs, for both practical and normative reasons. It proposes a set of guiding principles that should orient the legalization of all drugs and then fleshes out concrete regulatory proposals for specific drug markets, pondering their relative benefits and risks. Although anchored in a specific case study, the essay should be considered a broader contribution to enrich discussions as drug policy reform moves from state to national jurisdictions and from marijuana to other drugs. * Ernesto Zedillo, PhD., is the Director of the Yale Center for the Study of Globalization. Catalina Pérez-Correa, SJD, is a Professor at CIDE, Región Centro. Alejandro Madrazo, JSD, is a Professor at CIDE, Región Centro. Fernanda Alonso, LL.M., is a Ph.D. Candidate in Public Health at Johns Hopkins University. Published by Penn Law: Legal Scholarship Repository, 2019 108 U. Pa. J. Int'l L. [Vol. 41:1


The solubility of 6-chloropyridazin-3-amine in methanol, ethanol, n-butanol, N,N-dimethylformamide, acetone, cyclohexanone, ethyl acetate, and toluene at temperatures ranging from (298.15 to 343.55) K at atmospheric pressure was obtained using a synthetic method. The results showed that the solubility of 6-chloropyridazin-3-amine in these solvents increases with rising temperature. The modified Apelblat equation and λh equation were used to correlate the experimental solubility respectively. The calculated values with equations showed good consistency with the experimental values, and the root-mean-square relative deviation was less than 4.68 %. The enthalpy of dissolution and entropy of 6-chloropyridazin-3-amine were obtained by the van't Hoff equation, and the change in Gibbs free energy was calculated.


Despite the demand for pharmacists ' active participation in home medical care and cooperation with other professionals, their role in home medical care is not properly understood by other professionals. This study qualitatively analyzed the opinions of other professionals about their perceived need to cooperate with pharmacists. A semi-structured interview was conducted involving 4 visiting nurses and 2 certified care workers providing home medical care services in Aichi Prefecture, and the obtained data were qualitatively analyzed using a grounded theory approach. As medication management of patients at home was difficult due to not only patients ' physical factors, but also emotional and social factors, as well living, and factors, the ability for patients is essential. medication management was performed mainly workers, and a difference in the was observed between and nurses. Thus, must consider emotional barriers, such as concerns and hesitations pharmaceutical knowledge among other as well as conflicts the of the management excessive emphasis is placed acquire the ability and develop attitude to accept the feelings of and their families.


Dermatitis herpetiformis (DH) is a pruritic papulovesicular skin disease of unknown etiology. Its association with gluten enteropathy Is well-documented, and a mild malabsorption syndrome has been reported in patients with DH. It has been suggested that DH is the skin manifestation of a generalized immunologic disorder. The pathogenesis of DH is supposed to have a genetic predisposition in some individuals, where mucosal inflammatory reaction develops in the small intestine on exposure to the gluten in food. This reaction may cause destruction of the villi and development of mucosal atrophy. Plasma cells in the mucosa may then produce specific IgA, which in the blood can act as antibodies or immunocomplexes and attach dermal structures. Local release of inflammatory substances may thereafter cause pruritus and papulovesicular manifestations. The diagnosis of DH is established by skin biopsies from normal and perilesional regions, showing granular depositions of IgA in dermal papillae. Most (70-80%) patients with DH have patchy atrophic mucosal lesions located mainly in the proximal part of the gastrointestinal tract.' Absorption dysfunction shown by D-xylose absorption test, lactose tolerance test, or fecal fat excretion can, however, only be detected in 50% of patients. Symptoms from the disorder of the small intestine, such as diarrhea and weight loss, are found in only 10-20% of these patients. The mucosal changes can be normalized within a few months after


The article deals with the formation of the morphological category of speech type in the process of the development of German, which provides an explanation for the status of indirect speech Konjunktiv in its modern system as one of the grammemes of the category in question that has been generated from the optative as a result of restructuring the entire modal system of the German language.


The Purpose of this study is to suggest on the basic material of problems and development plans for the Ninth Icheon Sansuyu...


We present an overview of the current state of multidimensional modelling of type Ia supernovae and an example for surprising consequences of impoving the physics of the model. In this case, an improved handling of subgrid scale turbulence gives rise to lower burning rates and a decreased global energy release. While this result is too preliminary to be interpreted quantitatively, it shows that much work remains to be done before the turbulent deflagration model can be declared to be understood and/or insufficient to explain normal type Ia supernovae.


Tobacco crops were artificially damaged to simulate effects of hail in two series of experiments run over three years. In the first series, four treatments ranging from no damage to complete loss of leaves plus the apex were imposed when 5,10 or 15 leaves had unfolded. The performance of crops replanted or ratooned at the same stages was also measured. In the second series, the effects of lamina loss or midrib damage, or both in crops at early flowering were investigated. The first series showed that yield and quality were drastically reduced by severe damage at the 15 leaf stage. Yields where all the leaves were lost were only 940 kg/ha compared with controls yielding 2400 kg/ha. Replanted crops also yielded poorly at this stage (91 0 kg/ha) but ratooned crops produced satisfactory yields (1840 kg/ha) of good quality leaf. However, ratooning led to significant delays in harvest. In the second series, yields decreased from 2370 and 2030 to 161 0 kg/ha with loss of one-third and two-thirds of the lamina tissue, respectively. Damage to midribs caused additional losses of up to 400 kg/ha. However, only the most severe loss of lamina tissue depressed leaf quality.


A method for controlling a vehicle having a drive unit, - with at least two subsystems (10, 18, 20, 22) which via a connecting they communication system (24) to exchange information, - wherein at least one of the subsystems (10) is a control unit for controlling the drive unit of the vehicle, - said control unit (10) in at least one operating condition of the vehicle via the communication system (24) comprises a default value of said at least one further sub-system (18, 20, 22) (mokupsoll) for the dispensed from the drive unit torque to the to the drive unit generating combustion torque or is fed for the dispensed from the drive unit performance, characterized in that the control unit (10) transmits information regarding the actual value of the represented by the default size of the at least one subsystem (18, 20, 22).


Equilibrium configuration of order parameter in a nematic liquid crystal droplet with homeotropic anchoring of finite strength at the surface is studied numerically by using the Landau–de Gennes approach. It is found that a hedgehog-like configuration with a disclination loop of a small radius is stable for strong anchoring while an axial configuration without defect is stable for weak anchoring. A first-order phase transition from one configuration to the other occurs as the strength of the anchoring is varied. The critical anchoring strength turns out to increase almost linearly with the inverse of the droplet radius.


This paper contributes to the social interactions literature by utilizing data on households' residential sorting. We employ a standard neighborhood effects model in which households' valuation of neighborhoods derives from neighborhood effects in the formation of human capital and in the process of enculturation. We use micro data from the PSID merged, using geocodes, with contextual information at the levels of census tracts from the 2000 US Census. We find support for a key implication of neighborhood effects models: households with children are more likely to move out of neighborhoods whose attributes are not favorable to the production of human capital and the transmission of parents' cultural traits, and to move into neighborhoods with desirable such attributes. This effect is absent for households without children.


Abstract A new approach to resolve overlapping echoes is proposed. Inverse filtering is performed in a windowed frequency interval to avoid the enhancement of highly distorted signal spectrum. Using the partially inverse filtered signal spectrum as the data base, nonlinear spectral estimation techniques are then applied to resolve the number of overlapping echoes present and to obtain high resolution estimate of the individual echo time delays. Numerical and experimental results verify the effectiveness of the proposed new approach.


A number of errors in earlier reports of the infrared intensities of F2CO and their interpretation have been discovered and corrected in the present paper. The earlier values of ∂p/∂Si calculated using the CNDO/2 approximate quantum mechanical treatment have been corrected, and the previous results extended so that the calculated bond moments can be compared with the experimental values, similarly corrected. These results are now much more closely in agreement with chemical intuition that the earlier results implied.


Treatment objectives of cutaneous T-cell lymphoma can be achieved with a variety of modalities applied to the variable presentations of the disease. In this review, the goals of therapy are presented and each therapy is summarized in terms of its use to achieve those goals. After reviewing the modalities, the strategies are summarized in reference to each presentation of cutaneous T-cell lymphoma.


Dependent edema, ascites, and exertional dyspnea devel[ill]d in a patient seven months after pericardiectomy for [ill]strictive pericarditis. Cardiac catheterization documented [ill]strictive physiology. At the second operation, he was [ill]nd to have extensive mediastinal fibrosis that encased the [ill]rt. Postmortem examination showed a fibrocartilagenous [ill]skeleton that encased both ventricles. Possible etiologies this unusual reconstriction are discussed. [ill] Arch Intern Med 1984;144:2061-2063)


The living free radical random copolymerizations of styrene with methyl methacrylate initiated by benzoyl peroxide(BPO) were studied in the presence of TEMPO(2,2,6,6-tetramethylpiperidinyl-1-oxy) with the addition of malononitrile(MN).It was found that copolymerization was distinctly accelerated by the addition of small amount of MN.In comparison with the homopolymerization of St with MMA,these systems represented a dramatic improvement.The copolymerization of St with MMA achieved high conversion(93%) in 30 minutes at 125℃,when f_(St) is 0.2, = 31.21.The rate of polymerization is nearly 50 times higher than that without MN.Even at less styrene ratios at the monomer(f_(St) = 0.2),the molecular weight of the copolymer gradually increased with time and maintained a low polydispersity.The copolymerization of styrene with MMA proceeded in a living fashion indicated by the increase in molecules weight with time and conversion and relatively low polydispersity.The molecular weights can be controlled from 10000 to 23000 amu and polydispersities can be controlled from 1.1 to 1.5.In the all ~1HNMR spectra of polymers using MN as additive,we didn't find the peaks refered to additive and the peaks of end groups of polymers were still existed.


Part 1 The writer and his setting: biographical background - "A man on whom the sun has gone down", "Born in a half savage country", "This damn'd profession of writing", "Drinking the tone of things", "Full impetus of vehement will", "Absract years", "A blown husk that is finished" literary, cultural and political background - wearing masks, making it new - the "isms" of Modernism, the Chinese connection - language, poetry, philosophy, economic politics, sexual politics. Part 2 Critical survey: personae, imagism in practics, Cathay - homage to Sextus Propertius, Hugh Selwyn Mauberley, the Cantos, the language of the Cantos, aspects of the Cantos. Part 3 Reference section: brief biographies, gazetteer, bibliography, further reading.


REGIONAL REGISTERS To return to the establishment of the registers. At the headquarters of the Federal Bureau of Investigation (better known as the F.RI.), in Washington, D.C., there is established a 'Collection of over ten million sets of fingerprints, so finely sub-divided that the search for, and identification of, any given set of prints take a few minutes only. Therefore, in Scotland, with its population of 41 millions, one register would be sufficient, whereas in England and Wales, with a population of approximately 40 millions, the division of the country into four regions, one to include Wales, would suffice.


Somatic mutations in hematopoietic cells are associated with age and have been associated with higher mortality in apparently healthy adults, especially due to atherosclerotic disease. In animal models, somatic mutations are associated with atherosclerosis progression and myocardial dysfunction, especially when gene TET2 is affected. Preliminary clinical data, referred to ischemic heart failure (HF), have associate the presence of these acquired mutations with impaired prognosis.

 To study the prevalence of somatic mutations in patients with heart failure with reduced ejection fraction (HFrEF) and their impact on long-term prognosis.

 We studied a cohort of elderly patients (more than 60 years old) hospitalized with HFrEF (LVEF<45%). The presence of somatic mutations was assessed using next generation sequencing (Illumina HiSeq 2500), with a mutated allelic fraction of at least 2% and a panel of 55 genes related with clonal hematopoiesis. Patients were followed-up for a median of three years. The study endpoint was a composite of death or readmission for worsening HF. Kaplan-Meier analysis (log-rank test) and Cox proportional hazards regression models were performed adjusting for age, sex and LVEF.

 A total of 62 patients (46 males (74.2%), age 74±7.5 years) with HFrEF (LVEF 29.7±7.8%) were enrolled in the study. The ischemic etiology was present in 54% of patients. Somatic mutations in Dnmt3a or Tet2 were present in 11 patients (17.7%). No differences existed in baseline characteristics except for a higher prevalence of atrial fibrillation in patients with somatic mutations (70% vs. 40%, p=0.007). During the follow-up period, 40 patients (64.5%) died and 38 (61.3%) had HF re-admission. The KM survival analysis for the combined event is shown in Figure 1. Compared with patients without somatic mutations and after adjusting for covariates, there was an increased risk of adverse outcomes when the somatic mutations were present (HR 3.6, 95% CI [1.6, 7.8], p=0.0014). This results remains considering death as a competing risk (Gray's test p=0.0097) and adjusting for covariates (HR = 2.21 95% CI [0.98, 5], p=0.0556).

 Somatic mutation are present in patients with HFrEF and determine a higher risk of adverse events in the follow-up. Further studies are needed to assess the clinical implications of these findings.
 Figure 1

 Type of funding source: None


sepia photograph 10.3cm by 14.7cm - ruins Glengyle Mansion Coburg 1856 - built 1856 by prison labour from old Collingwood stockade. Shown here after fire in 1915.


Using recording equipment for sonic and ultrasonic range we recorded and collected Cicadetta cerdaniensis PUISSANT et BOULARD, 2000 on two localities in Poland, at Polana Polichno (Nida Valley, Malopolska Upland), and in Ojcow National Park (Krakow-Wielun Upland). These are the first records for the fauna of Poland. Additional new bioacoustic data are included.


Various quasiprobability distributions have been developed in the past using the Hilbert space of the single-mode light field. The development of a quasiprobability distribution associated with a phase operator has previously been impossible because of the absence of a unique Hermitian phase operator defined on the Hilbert space. Recently, however, Pegg and Barnett [Europhys. Lett. 6, 483 (1988); Phys. Rev. A 39, 1665 (1989)] and Barnett and Pegg [J. Mod. Optics 36, 7 (1989)] introduced a new formalism that does allow the construction of a Hermitian phase operator and associated phase eigenstates. In this paper we develop a quasiprobability distribution associated with the number and phase operators of the single-mode light field in the new formalism.


Blues, Funk, RB however, those same visitors wanted to treat not the contemporary blues, but rather the blues before 1960, for which the attending audiences in the 1990s were either aged or dead. …


.............................................................................. ii Executive Summary................................................................ iii Acknowledgements................................................................ v Chapter 1: Introduction ...................................................... 1 Chapter 2: The South as a Whole ...................................................... 9 Chapter 3: The Southern Strategy ...................................................... 12 Chapter 4: Congressional Power ...................................................... 15 Chapter 5: Partisan vs. Ideology Self-Identification................................. 16 Chapter 6: Ideological Tension ...................................................... 24 Chapter 7: Alabama ........................................................................ 27 Chapter 8: Arkansas........................................................................ 29 Chapter 9: South Carolina................................................................. 31 Chapter 10: Virginia........................................................................ 35 Chapter 11: Commonalities and Differences.......................................... 38 Chapter 12: Conclusion – The Democratic Brand.................................... 45 Works Cited................................................................................... 47


We consider a nonconvex optimization problem arising in the theory of global asymptotic stability of discrete time recurrent neural networks. Under certain weak conditions on the transfer functions we proved that corresponding nonconvex cost function has at most one point of local maximum over every hyperplane. We derived sufficient conditions for existence of a point of local maximum of cost functions over planes of less dimensions, and show that for standard transfer functions the number of points of local maximum of cost function over a plane may be bigger than the co-dimension of the plane.


Contents: Foreword. Preface. S.E. Nichols, T. Koballa, Framing Issues of Elementary Science Teacher Education: Critical Conversations. Part I: Conceptualizing Elementary Science Teacher Education. L.B. Flick, Being an Elementary Science Teacher Educator. K. Appleton, Science Pedagogical Content Knowledge and Elementary School Teachers. W.J. Boone, Teaching by Distance. S.K. Abell, Challenges and Opportunities for Field Experiences in Elementary Science Teacher Preparation. J. Koch, Relating Learning Theories to Pedagogy for Preservice Elementary Science Education. M. Fleer, "Meaning-Making Science": Exploring the Sociocultural Dimensions of Early Childhood Teacher Education. Part II: Intersections of Content, Pedagogy, and Practice. J.K. Olson, K. Appleton, Considering Curriculum for Elementary Science Methods Courses. V. Prain, B. Hand, Language, Learning, and Science Literacy. K.C. Wieseman, H. Moscovici, A Standards-Infused Approach to Curriculum: A Promising Interdisciplinary Inquiry. A. Jones, The Role and Place of Technological Literacy in Elementary Science Teacher Education. C.A. Harrison, Assessment and Elementary Science Teacher Education. Part III: Contextualized Practice and Professional Development. E.H. van Zee, Teaching "Science Teaching" Through Inquiry. V.L. Akerson, A.R. McDuffie, The Elementary Science Teacher as Researcher. J.R. McGinnis, Cultural Considerations. L.A. Bryan, D.J. Tippins, Employing Case-Based Pedagogy Within a Relfection Orientation to Elementary Science Teacher Preparation. M.G. Jones, J. Edmunds, Models of Elementary Science Instruction: Roles of Science Specialist Teachers. K. Appleton, Future Directions in Elementary Science Teacher Education: Conclusion.


If this reasoning is adopted, which this article contends it should be, LIBOR should fall within the purview of the Sherman Act, as it is a commodity and therefore part of A¢â'¬A"trade.A¢â'¬Â J. Douglas Richards & Michael B. Eisenkraft (Cohen Milstein)


We demonstrate the validity of the four-cell typology of career system by classifying 122 MBA graduates into the four cells by firm and comparing them on a range of variables. The data reveal signi...


The invention relates to a dashboard button shaft (10) with a built-in graduator. The dashboard button shaft comprises a shaft (15) with two ends and a disc (25) that is integrated with the shaft (15) and is close to one end of the shaft (15) which receives on dashboard button. The disc (25) comprises the built-in graduator (35). The graduator comprises a body (50), a tip (40), at least one arm (20) and at least one leg (30). The at least one arm (20) and the least one leg (30) of the built-in graduator (35) act conjunctively to generate an elastic force; the tip (40) is joined in one of slots (120) of at least one wall (110) of a dashboard button seat (100). Alternatively, a seal ring (140) is positioned between two walls (110) of the seat (100) so as to absorb noise due to movement of the tip (40) of the built-in graduator between two adjacent slots (120).


Two bioassays (fish mortality and fish erythrocyte hemolysis) were used to survey for the presence of toxic principles in aqueous extracts of 19 species of marine macro‐algae found in south Florida coastal waters. Extracts from six species (Chlorophyta—Anadyomene stellata (Wulfen) C. Ag., Caulerpa prolifera (Forsskål) Lamour., Penicillus capitatus Lamarck: Rhodophyta—Centroceras clavulatum (C. Ag.) Montague, Laurencia papillosa (Forsskål) Grev., L. poitel (Lamour.) Howe) showed lethal toxicity to the spotfin mojarra, Euconistomus argenteus Baird & Girard. Extracts from three species (Chlorophyta—A. stellata: Phaeophyta—Dictyota dichotoma (Hudson) Lamour.: Rhodophyta—Wrangelia penicillata C. Ag.) lysed erythrocytes of sea bream, Archosargus rhomboidalis (L.).


The impact of weather factors on seasonal abundance and population dynamics of Anosia chrysippus, a serious pest of Calotropis procera in Jammu region was studied during August, 2010rnto July, 2012. The pest remained active throughout the year and attained two population peaks first in the month of October (3.04 larvae/twig) and second during April (4.94 larvae/twig). Correlation studies revealed a significantrnpositive correlation between increase in temperature and pest infestation (R=0.720; P≤0.01). All other weather factors viz. average relative humidity and average rainfall had a negative correlation with incidence of the pest. The regression model developed indicated that the variation in pest population is strongly influenced by maximum temperature (R2=0.519) and average relative humidity (R2=0.594). The results indicated that weather parameters played an important role in the population build-up of the pest.


15 rural residential centres in Fengyang county are considered as units for judgement.It can be divided into three major utilization patterns:high-intensity,medium-intensity and low-intensity.Finally,with the usage of assessment model for intensive potential of rural residential centres,it can be predicted that in this area,feasible potential reaches 63.600 0 hm2 during 2005—2010 and 379.890 0 hm2 during 2005—2020.


This paper briefly introduces the related concepts of Internet of things (IOT). The applications based IOT is focus on the solution of testing alcohol when drunk driving. The design of smart alcohol testing system based on the IOT is proposed. The topology of the system is given. In the end, it shows deeply Smart Alcohol Testing system is the urgency of industry development wherever from personal, public service and the government needs. It can provide the better services of alcohol testing.


The cactus weevil, Cactophagus spinolae (Gyllenhal) (Coleoptera: Curculionidae), commonly attacks various species of Cactaceae (Carnegiea sp., Cereus sp., Cylindropuntia sp., Ferocactus sp., Hylocereus spp., Opuntia spp., and Stenocereus spp.) and Asparagaceae (Agave sp.) (Anderson 1948; Vaurie 1967; Ramírez-Delgadillo et al. 2011; BravoAvilez et al. 2014). Because of newly cultivated species of cacti and the continuing transport of wild species, the distribution of this weevil species and the number of its host plants could be expected to expand. In July of 2015, in a backyard in Cuernavaca, Morelos, Mexico (18.9812°, −99.2444°), a mating pair of C. spinolae was found on an individual of "reinade lanoche"or"pitayitanocturnadeespolones", Selenicereus hamatus (Scheidw.) Britton & Rose (Cactaceae). This cactus is valued by collectors for its large size and beauty of its flowers. Selenicereus hamatus is a climbing cactus with woody and cylindrical stems (2.5–3.0 cm diameter) (García 2008). It is naturally distributed in the Mexican states of Oaxaca, Puebla, and Veracruz (Bravo-Hollis 1978; Hernandez and Godinez 1994). However, it is now found throughout the country due to commercialization as an ornamental species. Further inspection of two S. hamatus specimens revealed symptoms of potential inner damage in six stems and one fruit. Dissection of plant tissues revealed curculionid larvae (Fig. 1). Five larvae were reared to adult emergence, and two were preserved. Additionally, on 10 November, an adult specimen was collected feeding in one of the S. hamatus (Fig. 2), confirming its capacity for mating and feeding on this cactus. All specimens were determined with the taxonomic key of Vaurie (1967) Figs. 1–3. Cactus weevil on Selenicereus hamatus. 1) Larva in fruit; 2) Larva in stem; 3) Adult feeding on stem.


It is considered that in Francos dictatorship teaching profession was mainly integra- ted by women from outside of the Basque Country. They were not born from Araba, Bizkaia, Gipuzkoa and Nafarroa. After studying and analysing the characteristics of the teaching profes- sion in that period, we have reached the conclussion that, in fact, the vast majority of teachers in the Primary Public School werw women. It is also true that there was a huge arrival of foreingn teachers.They could not understand or speak Basque and for that reason they werw called "make- to". Having said that, we would also like to underline that in Gipuzkoa there were many teachers from the Basque Country, mainly fron Nafarroa. However, few of them kenw the Basque langua- ge. On the contrary many students werw not able to understand or speak others languages apart from Basque. Consequently, there was a huge confrontation between teachers and students.


Thiophenes, including benzothiophenes and dibenzothiophenes, undergo a variety of reactions with transition metal complexes that lead to products in which the thiophene is partially reduced or cleaved at a C−S bond. The specific types of reactivity depend on the modes of thiophene coordination to the metal, which in turn depend on the particular metal and its associated ligands. It is the intent of this review to organize these numerous reactions of thiophenes into categories that illustrate distinct patterns of reactivity. It is hoped that an understanding of such patterns will stimulate the use of thiophene−organotransition metal chemistry in synthetic organic chemistry.


The present invention provides a method for depositing an oxide coating on an inorganic substrate, the process provides an aqueous composition comprising a tetraalkylammonium polyoxometalate anion and hydrogen peroxide; inorganic based aqueous composition the wood is contacted for a time sufficient to precipitate the hydroxide derived from the polyoxoanion the surface of the inorganic substrate, the step of forming the inorganic substrate is initially coated; is well initial coating the inorganic substrate, forming an oxide coating derived from the polyoxoanion and heating time sufficient on inorganic substrates to convert the hydroxide to the oxide; encompasses a method of provide. Inorganic substrate, a ceramic material or a semiconductor material may be a glass or other insulating material, and the ceramic material may be a lithium-ion battery cathode materials.


Abstract The utilization of network structure to impart stable orientation to a rubbery material has been largely unexploited to date. It is demonstrated that the presence of a double network will ...


During the high-power charging process, the heat generated by the power battery is significantly increased, resulting in a significant temperature rise, which will bring safety hazards and worsens capacity degradation. In this study, we focus on the energy storage system composed of LiFePO4 pouch battery cells whose capacity is 30Ah. The coupling calculation between the one-dimensional electro-chemical model and the 3D heat generation model is realized. The accuracy of the model is verified by charging the battery at different rates. The results show that the inlet flow rate and the cooling channel size within a certain range has a great influence on the cooling effect of the battery pack during high power charging process. Comparing the temperature distribution of the battery pack under different charging rates, the electrochemical-heating coupling model established in this study can truly reflect the heat generation of the battery. Through the calculation of the heat generation of the battery pack, the boundary conditions of the cooling system design can be found, which provides a basis for the optimal design of the conditional cooling system for battery high-power charging.


We apply Lakshmikantham's generalized quasilinearization method to an initial value problem involving a nonlinear integro-differential equation with initial time difference and obtain monotone sequences of lower and upper solutions converging uniformly and quadratically to the unique solution of the problem. AMS(MOS) Subject Classification: 45J05, 34D10, 34D99.


By penetrating into the following issues, including "Why to authorize?", the conditions for authorizing, the bounding terms for authorizing and the function of authorization, this paper expounds the effectiveness of management brought by authorization. This paper also conducts an analysis into the authorizing problems existing in the management of state own enterprises, on the basis of which the author brings forth his view that to raise the administrative efficiency in state own enterprises authorization must be highly held of.


We present an Arduino approach to collect pressure and temperature data from electronic sensors. Using a constant volume-metal-vessel immersed in a water bath and changing its temperature, we measure the pressure as a function of the temperature inside the vessel. With this apparatus, it is possible to demonstrate Gay-Lussac's law. Based on measurements of pressure and temperature we can establish the absolute Kelvin temperature scale.


A concept for the efficient generation of surface plasmon polaritons (SPPs) with a duration of very few cycles is presented. The scheme is based on grating coupling and laser pulses with wavefront rotation (WFR), so that the resonance condition for SPP excitation is satisfied only for a time window shorter than the driving pulse. The feasibility and robustness of the technique is investigated by means of simulations with realistic parameters. In optimal conditions, we find that a $29.5$~fs pulse with $800$~nm wavelength can excite a $3.8$~fs SPP ($\sim 1.4$ laser cycles) with a peak field amplitude $2.7$ times the peak value for the laser pulse.


The Transural steppe is a cultural contact zone between areas east and west of the Ural Mountains. Mobile pastoralism is the traditional way of life in the steppe, while sedentary cultures constitute an exception, probably as a result of climatic variations. A change of lifestyle together with other innovations is documented at the turn of the 3rd to the 2nd millennia BC and often believed to have been accompanied by a shift to agro-pastoralism. To examine the ecology and economy in the Bronze Age steppe, we employed a combination of methods. As proxy-data, plant macro-remains from archaeological excavations of Sintashta fortified settlements and pollen from off-site archives were used for a high-resolution palaeoenvironmental reconstruction. Statistical comparisons of past and present pollen spectra show no significant differences in vegetation distribution. This allowed us to map the recent vegetation units by multispectral satellite imagery and to use them for modelling. Models further incorporate steppe productivity, carrying capacity and population figures to estimate herd sizes. Even if the climate was suitable for agriculture, evidence is missing from all botanical records. The economic mainstay was animal husbandry. Models consider autonomous activity zones of at least 4 km radius surrounding each Sintashta settlement where grazing resources could easily sustain the estimated population and their livestock. The river is seen as the determining factor to settle in this region as it provided constant access to water and valuable natural grazing areas. During dry years and winter, the productive meadow steppes functioned as reserve pastures.


Objective: Potassium dichromate (K2Cr2O7) is a potent pollutant for human and animal health. The pur- pose of the current work is to compare the effect of K2Cr2O7 using variations in the dose, route of administration and duration of exposure in male and female Wistar albino rats and to research the interaction of chromium and selenium with a special focus on hematopoiesis. Materials and methods: K2Cr2O7 was subcutaneously administered alone (10, 50 and 100 mg/kg body weight) or K2Cr2O7 (10 mg/kg) in association with selenium (0.3 mg/kg) was administered to female Wistar albino rats. Male rats received in their drinking water K2Cr2O7 (30 mg/L/day) alone or in association with Se (0.3 mg/L/day) for 20 consecutive days. The hematological parameters were evaluated on days 3, 6 and 21 after subcutaneous (sc.) treatment in female rats and on days 10 and 20 after oral administration in male rats. Results: K2Cr2O7− induced during the first three days a significant (p < 0.05) dose-dependent decrease in the number of ery- throcytes, platelets, leucocytes, lymphocytes and the hematocrit levels, and a dose-dependent increase in the number of granulocytes and monocytes. In the drinking water, chromium sc. significantly decreased the number of leucocytes and lymphocytes on day 10 after treatment and elevated the number of granulocytes and monocytes 20 days later. Selenium sc. counterbalanced the hematotoxic effects of chromium in female rats. Conclusion: These results suggest that the selenium has a protective role against the hematotoxicity of subcutaneous chromium in female Wistar rats.


The Multi-attribute decision making is a decision making way,in this way we can put up to estimate and select the suitable project,which is multi-attribute.The Analytic Hierarchy Process(AHP) is a better decision making,which is not mathematic former,it is a mode of decision making,through which we can go along to estimate different complications in the field of society and economy.The AHP has the peculiarity of nature,agility;and it is prone to be understood,which can be unionized in the existing system info all right.The decision maker can accept it and account for the matter.The AHP incarnate that analyzing,estimating,synthesizing are the basic tincture of the person's decision making.The paper introduces the basic approaches of the AHP,the application examples of the AHP and the conclusions of the virtues and the limits about the AHP.


IT was as the result of examining the role of the suhdru in the early Amorite kingdoms, about which I have written elsewhere, that my attention was drawn to the status of the role of the na'ar in Israelite society. The word na'ar is almost everywhere translated under two headings: (1) child, lad, young man; (2) servant. It is the purpose of this article to demonstrate that these renderings are inadequate and produce a totally false impression of the person involved. Nacar undoubtedly means a young male, whether he is a babe-in-arms or a young man. What seems not to have been realized till now is that he is a young male of high birth. The significance of this statement, we shall demonstrate, affects the traditional rendering "servant," which does not distinguish the na'ar from other servants, for whom different Hebrew words are consistently used. The word na'ar appears in West Semitic (Ugaritic and Hebrew), and the root is unknown elsewhere in the literature of that linguistic area. In the span of Israelite Hebrew literature it serves to express a remarkable range of age-groups, as traditionally rendered "lad, youngster." It is used of a child yet unborn (Jud. 13:5-12 passim), or one just born (1 Sam. 4:21). In 1 Sam. 1:22 the na'ar is not yet past the stage of sucking at the breast, while the same term describes the babe after weaning two verses later. In Exod. 2:6 the na'ar is three months old.


The invention relates to a method for manufacturing a membrane electrode assembly (12) for a fuel cell, the method comprising the steps of: - placing a blank (18) of the membrane electrode assembly (12) comprising a membrane (50), in a protection device (10), wherein the protective device (10) for the blank (18) on both sides partially covered; - inserting the protection device (10) together with the blank (18) into a mold; - preparing at least one seal (16) on the blank (18) within the tool. In addition, the invention relates to a protective device (10) for performing the method according to the invention.


The utilization of lubricating oils is an important factor in the rational use of petroleum products in engine motors. Three lubricating oil samples were separated using dimethyl poly siloxane as stationary phase packed in capillary column in gas chromatography. The light hydrocarbons from ethane and heavy paraffinic hydrocarbons up to C45 + were completely separated qualitatively and quantitatively in one run using one column. It has been found that capillary column of length 60 m enough giving good separation of sharp and symmetric peaks which positively reflected on the quantitative determination of all paraffinic hydrocarbons in crude oil samples.


The purpose of this paper is to describe briefly and in a general way several schemes used to calculate the motion of smoke through a structure or part of a structure involved in a fire. Calculations of this type are required if we are to understand the spread fire through the structure and if we are to learn how to write building codes and other regulations which can provide the best possible protection for building occupants. For example, one of aims of designers of high rise buildings is the incorporation in their designs of regions where people can be protected from contact with cornbustion products without the requirement that they be able to escape from the building. Another aim is to restrict combustion products to the floor of the fire origin at least and, if possible, to a part of that floor. Finally, consider the simpler problem posed by the requirement that a ceiling or wall of a burning home be opened to change the flow of smoke such that firemen can approach the fire. To obtain a solution of each of these problems, we must be able to calculate the effects of smoke control measures (active or passive) on the gas motion.


Objective To evaluate the safety and efficacy of QUILLTM self-retaining suture (QUILLTMSRS) in laparoscopie partial nephrectomy.Methods Sixty-three patients (39 males,24 females) with renal tumor accepted laparoscopic partial nephrectomy in Peking Union Medical Hospital from February 2012 to January 2013.The ages ranged from 38 to 75 years.The tumor sizes varied from 1.5 cm to 4.5 cm.According to the device of renorrhaphy,they were divided into 2 groups.Vicryl suture was used for renorrhaphy in 32 patients (Group 1),and QUILLTMSRS was used in 31 patients (Group 2).Renorrhaphy was performed in two layers for both groups,with a closure of deep vessels and the collecting system with 4-0 absorbable suture,followed by a running closure of the renal parenchyma and renal capsule.Demographical and perioperative parameters including age,body mass index,tumor size,R.E.N.A.L score,estimated blood loss,warm ischemic time,length of hospital stay were recorded and compared between the 2 groups.Results Renorrhaphy was successfully performed in all the 63 cases without conversion to open procedure or nephrectomy.The estimated blood loss and length of postoperative hospital stay were not significantly different between the 2 groups (P>0.05).But warm ischemic time was significantly shorter in QUILLTM SRS group than that in Vicryl group (22.2 vs 26.7 min,P<0.001).Conclusions QUILLTMSRS could be safe and effective for renorrhaphy in laparoscopic partial nephrectomy.It could make laparoscopic renorrhaphy easier and reduce warm ischemic time significantly.

Key words:
Barbed suture;  Knotless;  Partial nephrectomy;  Laparascopes


The article presents the results of examination of 112 patients with cerebral paroxysmal condition at the age of 17-27. The authors studied complains, neurological status. Free radical status in blood serum has been studied. After an attack (epileptic seizures, syncope condition) activation of free radicals with hyper function of active forms of oxygen and lipid peroxide oxidation. There is moderate activation of free radical processes at the background of morphological damage of cerebral tissues as the cause of cerebral paroxysm. The authors discuss the ways of correction of the revealed pathologies.


Polymers are very large molecules, or macromolecules, formed by the union of many smaller molecules. These smaller units are termed monomers before they are converted into polymers. In fact, the word "polymer" has a Greek origin meaning "many members." Natural polymers have been around since the early times in Planet Earth. Life itself is linked to polymers since deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and proteins, which are essential to all known forms of life, are macromolecules. Cellulose, lignin, starch, and natural rubber are just a few other examples of natural polymers. Some of these polymers were used by early human civilizations to produce simple artifacts; for example, the play balls from natural rubber for the ball game of several of the Mesoamerican civilizations (which contained ritual content and not only entertaining purposes). In the 1800s, natural polymers began to be chemically modified to produce many materials, such as vulcanized rubber, gun cotton, and celluloid. Although natural polymers are very important, this book is mainly concerned with synthetic polymers, especially organic synthetic polymers. The chemical reaction by which polymers are synthesized from monomers is termed polymerization; however, this is a generic term, since there are a number of chemical mechanisms involved in different polymerization reactions. Synthetic polymers are relatively modern materials, since they entered into the technological and practical scene only in the first decades of the twentieth century. This makes them very different from some other materials that have been known to humanity for centuries or millennia.


Optical and electrical properties of SiGe strain‐adjusted superlattices have been studied. Diode structures were processed into waveguide geometries to investigate the role of optical confinement and the lowering of cubic symmetry with regards to the polarization properties of interband absorption and emission. The polarization anisotropy of the absorption coefficient suggests that the heavy‐hole band of strain‐adjusted Si6Ge4 superlattices is the top valence band.


In the article the methods of balance function formation in preschool children with musculoskeletal system disorders are systematized and analyzed. In the basis of dynamic stability correction in this children contingent were laid phylogenetically predisposed mechanisms of the postural aplomb system, reflected in periods of early
child ontogeny: vestibular - visual - proprioceptive - gift - oculomotor. To improve each of these input channels of the aplomb postural system, a specific technique algorithm for the development and correction of the balance function in preschool children with motor disorders was developed. For the vestibular channel it is suggested to
use methods of hydraulic inverted (mirroring), "weightlessness", smoothness (metered angular accelerations). For the visual channel you can use the methods of "dark room", "tuning fork", "dawn". Proprioceptive channel improvement of the postural aplomb system involves the use of gradually reducing methods of bearing surface area,
strengthening proprioceptive sensations (the method of "two fans"). The given canal of the child vestibular system can be developed using such methods as "topographic", "two-axis – one-axis", sensory stimulation, contrast method, and also the method of "stilts". The oculomotor system of child with balance state disturbances can be
improved by the method of expanding oculomotor space-time eyes possibilities, the method of the ball, as well as the method of visual selective object capture, separating it from a variety of objects or from fleeting environment. This classification of methods are given with their conditional division into natural, phylogenetic and ontogenetic predetermined, and artificial, based on the use of the subject-spatial component (equipment, simulators and inventory), as well as the use of the possibilities of information and computer technologies with reverse biological bonds.
The prospects of studying the development methods and correction of balance function in preschool children with motor disorders is the development of specific exercise complexes for each of the developed methods, followed by their practical testing in this children contingent.


In this treatise, in order to derive the feature of Korean Eastern folksong, I tried to search the musical characteristics by comparing the existing researches related to the folksong of Kyungsangdo, Kangwondo and Hamkyungdo, with thirty-four pieces of Hamkyungdo labor song(work song) recorded in two folksong book of 「JO-SEON MINYO BACGOKJIB」 and 「JO-SEON MINJOKEUMAK JEONJIB」. The researching result mentioned the above is as follows. 〈Musical Features in Hamkyeongdo Folksong〉 1. In short, there are Menaritory, Kyeongseotory and extraneous musical factor are mixed in Hamkyeongdo folksong(labor song). That is, it is certified that Menaritory circle is the mainstream in traditional labor folksongs among Hamkyeongdo folksongs. 2. Singosantaryeong can be classified into Menaritory and Kyeongtory(the second Kyeongtory) according to the point of view. 3. It is found that the progressing feature of shouting from high to low tone. 4. The folksongs under the category of Dondolnaly can be construed into New Folksong or the folksong relating to Changga. 5. The compass of Hamkyeongdo labor songs is about one octave from lower 'mi' to higher 'mi'. 6. It has three scale structure that the five sound, the four sound and upper compass are limitedly used. 〈Musical Features in Eastern Folksong〉 1. There is Asayongtory which is the intermediate form of Kyeongtory and Menaritory. 2. There are three kinds of singing skill. One is shouting, the other is sounding plain and the third is sounding lower. 3. It has four tone in going-up, five tone in going-down and non-hemitonic scale. 4. It is the intermediate form of Yukjabagitory and Menaritory.(Kyeongnam province folksong, shamanic songs) 5. It is found the intermediate form of Menaritory and Susimgatory.(a boating song on Han river) 6. It has a tendencies to progress going-down from "Re" to "Do", and from "Ra" to "Mi" by way of "Sol". 7. Comparing to the other tories, the distribution area of Menaritory is very wide. 8. It can be found the form of Menari with heroic airs of Kyeongsangdo rather than sorrowful emotions.(long song in MoonKyeong weeding song) 9. There are midway cadence completed by "Mi" and perfect cadence completed by "Ra".


With similar to actual engineering rock mass of roadway, three dimensional physical simulation test study was performed on the physical model in order to research the damage characteristics of deep soft rock roadway and its mechanism further. Many factors were considered in this paper, including the different stress level, lithology(soft rock and hard rock), rock mass structure characteristics(joint and bedding distribution) and supporting forms, etc.. According to comparing with the surrounding rock stress state and displacement, which is under the condition of the weak and the strong support of different internal depth, the reasons for damage of zonal disintegration and the influencing factors were obtained. The rotation direction of principal stress and effects on the destruction of the surrounding rock of roadway were puts forward at the same time. The deep roadway zonal rupture is mainly to the outcome of combined action of shear and tensile damage preliminary. It is of great significance for the exploration of soft rock deformation and failure regularity as well as the guideline of supporting technology.


Three landmass groups and three oceans may be distinguished for the Earth since the Neoproterozoic. The former consist of the Laurasia, Pan-Cathaysian and Gondwana landmass groups, the latter comprise paleo-Asia Tethys and paleo-Atlantic oceans, respectively. The main body of China paleocontinent belongs neither to the Laurasia continent nor to Gondwana continent, rather than to land blocks in Tethyan ocean basin system between the two continents. The present paper interpretes these land blocks as Pan Cathysia landmass group, which may be matched in scale with the above-mentioned landmass groups. Pangea is finally formed by two phases large- scale opening and closing and major intracontinent convergence. Naturally, the formation of Pangea indicates a kind of dissipation mechanism of mantle dynamic and thermal energy, which have constructed a unified dissipation system of dynamic and thermal energy. The mineralization is characterized by multicydicity, transition, inheritance and superimposition. The eastern Tethys has gone through four stages of evolution: proto-Tethys paleo-Tethys, meso-Tethys and Cenozoic intracontinental convergence. The mineral resources in the study area might have been formed in individual stages cited above. However, the most important minerogenetic period may occur in the stage of paleo- and meso-Tethyan oceanic crust subduction ocean basin consumption, and two phases of relevant intracontinental convergence during the Indo-China phase, the late Yanshanian and Himalaya phases. A series of geologic events such as intense tectonism, magmatism structural deformation and displacement, and formation of tectono-sedimentary basin are all responsible for the formation of the unified minerogenetic-geological field system, which, in turn, facilitates the formation of the nonferrous and precious metallic ore deposits in this area. Especiously, in the Cenozoic, the activation, removing, mixing of the ore-forming materials derived from the crust and the mantle resulted not only in


Positive affectivity plays an important role in the endowment of resilience, which in turn is an important factor for individuals' adaptation to adversities in the changing environment. Based on hope theory and the Science of Well-Being we investigate a ternary model (character, motivation, and regulatory mode) for individual empowerment that promotes positive affectivity. A total of 1,876 participants, four separate samples, responded to the Positive Affect and Negative Affect Schedule (Study I-IV), the Temperament and Character Inventory (Study I), the modified Situational Motivation Scale (Study II), the Regulatory Mode Questionnaire (Study III), and the modified Connor-Davidson Resilience Scale (Study IV). We investigated, separately, each empowerment component's relationship to positive affect (Study I-III) and the positive affect-resilience relationship (Study IV). Four regression analyses showed that character (β = .28; Study I), intrinsic motivation (β = .35; Study II) and locomotion (β = .53; Study III) predicted positive affect, which in turn, predicted resilience (β = .53; Study IV). The ternary structure of empowerment (character, intrinsic motivation, and locomotion) does indeed predict positive affect thereby endowering individuals with a strength that emerges as resilience. However, the Ternary Empowerment Model suggested here needs to be further developed and studied in order to ensure that it actually is ternary in nature.


Room temperature superconductivity has been reported for a carbonaceous sulfur hydride (CSH)under high pressure by Snider et al [1]. The paper reported sharp drops in ac magnetic suscep-tibility as a function of temperature for six different pressures, that were interpreted as signalingsuperconducting transitions. Recently, two of the authors of ref. [1] posted in ref. [2] the underlyingdata for the ac magnetic susceptibility of CSH reported in ref. [1]. Here I provide an analysis ofthese underlying data. The results of this analysis call into question the generally accepted viewthat carbonaceous sulfur hydride is a room temperature superconductor


evels of carcinoembryonic antigen(CEA) in gallbladder bile
were determined in 4 1patients,Benign gallbladder diseases including stone and polyp showed
CEA values ingallbladder bile less than 500ng/ml,whereas in patients with gallbladder cancer
CEA valueswere beyond 500ng/ml with the mean value three-folds higher than that of benign
disease.Webelieve assessment of CEA level in gallbladder bile would be a good indicator for
gallbladderstone associated with carcinoma and malignant polyp。


Abstract Recent developments of Landau theory applied to ferroelectric structures are reviewed: (1) Influence of size and surface on the properties of phase transitions in film, cylinder and sphere geometries. The surface effect is described by an extrapolation length, which is positive when the surface ferroelectricity is weaker than that of the bulk and negative when it is stronger. The theory predicts a size driven phase transition, as observed experimentally. (2) Ferroelectric super-lattices. Landau theory has been used to obtain expressions for static properties such as transition temperatures and polarisation profile, and also the spectrum of tranverse optic modes. (3) Polarisation reversal. A discrete form of Landau theory has been developed to simulate the polarisation reversal process. This model gives a clear picture of the time evolution of polarisation under an applied switching electric field.


This is a naturalistic, quantitative study of the emergence of tense notion of pastness and the aspectual notion of punctuality in a visually impaired -but otherwise normal -child's acquisition nf English from 24 to 54 months of age. Naturalness of the sample was safeguarded by the elimination of imitated and repeated utterances as well as those for which the tense or verb had been modeled by the caregiver. It was found that 1) Stem change was significantly related to the aspectual notion of punctuality throughout the period of the study, as was -ed during some periods and with some populations of verbs. 2) Due to strategies typical of visually impaired children Seth extracted the form didja from the input directed to him and used it -without interrogatory, person/number or aspectual reference -for 10 months as a simple marker of ~ tense. 3) Stem change, -ed, and didja all appeared at 24 months. 4) The change Qf state notion was not significantly related to any morphological marker, though it figured in a disproportionate share of the utterances. Conclusions: 1) The solid mapping of stem change and the more marginal mapping of -ed onto the notion of punctuality, and the mapping of unbound didja onto the pascness notion bear out vi claims that children expect aspect -specifically punctuality to be marked nearest the verb and tense further away. 2) The simultaneous emergence of the marking of both semantic notions leads us to suggest that claims about the relatively late emergence of tense arise from observing children's interaction with the peculiarities of IndoEuropean verb m0r~hology the children, that is, expecting stem change to mark aspect -rather than from the asserted cognitive difficulty of tense notions for twoyear-olds. 3) The high cognitive salience -relatively high text frequency -of the change £i state notion gives the false impression that it is also semantically relevant. That this is not true underscores the independence of language and cognition.


King Cobra is a largest venomous snake in the world. An attempt was made to breed this snake in captivity as per the captive breeding program of Central Zoo Authority, India for the conservation of endangered species. Six male King cobras and four female King cobras were selected for the breeding program. These snakes were housed in a scientifically designed off-display facility. The snakes showed courtship behavior in March. The female kings built the nest from bamboo leaves and eggs were laid. The eggs were artificially incubated and hatched after 87 days.


The ballistic behaviour of thick steel armour plate at different obliquities has been investigated. Ballistic experiments were conducted in the velocity range 300-800 mls at 0°, 15°, 30° and 45° obliquity .A steel, conical projectile or 6.1 mm diameter was impacted on a 10 mm thick steel armour plate. At 30° and 45° obliquity, the plate offers protection up to a striking velocity of 800 mls. At zero obliquity, the plate provides protection below 6~ m/s. The depth of penetration decreases with increasing obliquity. The plate resistance does not decrease at higher obliquity observed in an earlier work.


The extraction of plutonium by triethylene glycol dichloride (trigly) has been investigated briefly. The effect of (1) the valence state of the plutonium, (2) the concentration of nitric acid, (3) the concentration of ammonium nitrate and (4) the conditioning of the trigly was measured. The solubility of plutonium IV trigly was found to be 70 mgms/ml. Solutions of plutonium in trigly and in concentrated nitric acid solutions have been examined spectrophotometrically. (auth)


The 2030 Agenda for Sustainable Development seems to be easy to communicate. The 17 Sustainable Development Goals are so powerful per se that one could think the messages they carry are relatively easy to spread. And it might be a rightful thinking if it wasn't for statistics and data. From the outset, assessing the 2030 Agenda from the communication point of view, the fact of entrusting the ownership of the Goals to the countries and, consequently, making the National Statistical Offices accountable for providing information necessary to measure the distance to the Goals accomplishment, was a genius move. However, it is well known that data – as much as they are vital for governments, media, academia and citizens – are not easy to understand if they are not well communicated. So, the challenge is not in communicating the SDGs, but in communicating data and statistics for SDGs.


In the title compound, C13H10ClNO, the central C—N bond has considerable double-bond character and the N—O bond indicates a formal negative charge on the O atom. The molecule is stabilized by an intramolecular C—H⋯O hydrogen bond. The geometry about the C=N bond is Z [C—C—N—O torsion angle = −4.2 (3)°] and the phenyl and benzene rings are trans-oriented around the C=N bond. The phenyl and benzene rings make a dihedral angle of 56.99 (2)°.


Since the separate independence of Senegal in June 1960, after the breakup of the Mali Federation, organized political opposition in Senegal has not been able to maintain the position which it enjoyed before independence. The failure of the opposition can be explained only in part by reference to the repressive measures adopted by the government over this period; it should also be seen as a result of the internal weaknesses of the opposition itself. The purpose of this article is to outline the various conditions which have enabled the governing party, the Union Progressiste Sénégalaise (UPS) of M. Leopold Sédar Senghor, to remain in power until the present time, despite its own lack of strict internal discipline or general sense of purpose.


Objective To treat acute renal failure complicating cardiac surgery, for avoiding dialysis, decreasing morbidity and mortality. Methods From January 1998 to November 2000, 50 patients manifested acute renal failure or dysfunction despite adequate postoperative cardiac output and stabilized hemodynamic function. Group A (20 patients) were given intermittenly doses of furosemide, while group B (30 patients) were given continuous infusion of furosemide and dopamine with intermittent mannitol and furosemide; subgroup A1 (13 patients) and subgroup B1 (20 patients) were immediately treated after 3 hours of oliguria (urine volume 0.5 ml/kg/h); while subgroup A2 (7 patients) and subgroup B2 (10 patients) were started to treat after serum creatinine level along 110 umol/L or 50% over the baseline in addition to 3 to 2 hours oliguria, this subgroup was further divided into early and late dialysis groups according to the cardiac function and hemodynamic stability before performing dialysis. Results Group A1: diuresis occurred in 7 patients (53.8%), and 6 early dialysis patients (46.2%), among then 1 patient died (7.7%). Group A2: 5 patients (71.4%) died among the 3 early dialysis patients and 4 late dialysis patients. Group B1: diuresis occured in 18 patients (90%) and 2 early dialysis patients (10%) with no death. Group B2: diuresis occured in 3 patients (30%), 5 early dialysis patients and 2 late dialysis patients with 3 death (30%). Conclusion To treat patients manifesting acute renal failure or dysfunction poatoperatively despite stabilized cardiac function and hemodynamics are important, and early diagnosis and treamtnet with diuretics and early dialysis are advocated.


Objective- To study the clinical manifestation and CT features of cerebellar hemorrhage in the elderly patients in order to make early diagnosis and treatment. Methods- The clinical manifestation, CT scanning, sites and causes of hemorrhage, as well as the treatment and the prognosis of 27 elderly patients with cerebellar hemorrhage were analysed. Results- The common presenting symptoms in the senile group were vomiting and vertigo, while there were headache and vomiting in the non-senile group. Blood pressure was markedly higher in 20 cases in the elderly patients. There were also more cases with water and electrolyte disturbance, renal function insufficiency, electrocardiogram abnormality and pulmonary infection. Conclusion- The clinical manifestation of cerebellum hemorrhage are not typical in the elderly. Hypertension and arteriosclerosis are the main etiology of this disease. The CT or MRI scan is helpful for early detection.


This paper focuses on Vasily Shukshin's "working records" dated from 1966. It is established that a lot of contexts and names are important for the interpretation of these records: from the antique myths to Russian literature. In the paper, it is proved that the motive of the waterway of a ship appears in Shukshin's texts as the concentrated symbol of spiritual aspirations, warm rushes, as the allegory of movement towards the aim and the overcoming of obstacles. At the same time, it is also a symbol of moral ascension, which is shown by the reflections about intelligence as the aim of the artist. The conclusion drawn is that the poetics of Vasily Shukshin's texts represents a very open and dialogical structure with wide referential installations.


Objective To evaluate the contrast-enhanced digital subtraction MRI in the diagnosis of vertebral metastasic tumors. Methods 66 vertebral metastasic tumors in 43 patients were examined with conventional MRI (T_1WI,STIR and Contrast-enhanced T_1WI) and contrast-enhanced digital subtraction MR imaging.All lesions were histologically proved.The quantity and characteristic imaging signs (including spiculation,bull eye sign and irregular edge) of lesions were detected separately by different sequences.K independent samples test was used.Results The detection rates of 35 vertebral metastasic tumors with vertebral morphological changes were same in all MR sequences.But in the other 31 lesions without vertebral morphological changes,the detection rates were different and STIR was the highest in all sequences.Contrast-enhanced digital subtraction MRI was more sensitive than all the conventional MR sequences in finding characteristic imaging signs with statistically significant differences.Conclusion Contrast enhanced subtraction MRI is an useful and convenient technique which has great value in finding vertebral metastasic tumors and depicting the characteristic imaging signs.


The purpose of this paper is to complement prior research on competitive and cooperative dynamics within regional clusters. Through a longitudinal investigation I observed the role cooperation and ...


The electro-mechanical characterization of MEMS diaphragms for acoustic applications is introduced in this paper. The samples under test are fabricated with the 0.35 AMS CMOS process with front-side surface etching post-process. The goals of the experimental activities are to verify the performances and repeatability of fabrication process and to identify the static and dynamic properties of diaphragms in comparison to the predictions of FEM models. In order to verify the applicability of this kind of devices to acoustic applications, the pressure generation in air has been measured with a measuring microphone with appreciable results.


The phrases 'townscape' and 'landscape character' are not used very often in common language, although we meet the meaning of these notions day after day. In scientific language, the definitions of settlement and landscape sometimes merge into each other, while at other times are totally different. What do we mean by townscape and what by landscape character? Is it possible to separate the two? The answer is constantly changing during history, according to the spirit of the age and the field of science. Despite the differences and formation, the various approaches converge in many aspects: we always mean a continuously changing, dynamic, spatial, physically distinct visual, and also a geographical spatial unit, which surrounds us. The definition of this, and a deliberate and controlled development are becoming more and more important in landscape and urban planning. At the end of 2016, a new genre, the so called Townscape Design Guide was introduced by law on local planning. In 2016, the national landscape character project had also begun. The phrases in the title refer to these new, national professional 'genres'. The aim of the study is to get to know these two, parallel processes, to reveal their connections by interpreting the Hungarian legal system, and the international background that influences it.


Chemical hazards may occur in any phases of the different livestock production systems. Aim of this review is to address an update about the key issues related to the risk of contamination in foods of animal origin by environmental contaminants linked to industrialisation or urbanisation (e.g., heavy metals and persistent organic pollutants), and natural contaminants (e.g., mycotoxins). This review deals with current issues and future perspectives on the complex issue of the safety of feeds and foods of animal origin, by taking into account the estimation of the occurrence of chemical residues in food, the hazard identification and characterisation of mycotoxins in animal feeds, and the analysis of feedstuffs as a tool to control and evaluate food safety.


A recent report from the Institute of Medicine (IOM) said the National Cancer Institute's cooperative group program is not prepared to meet current opportunities in cancer research despite its contributions to past progress. The IOM criticized the program for being slow, bureaucratic, inefficient, and unproductive. Simultaneously, the American Society of Clinical Oncology (ASCO) published a survey showing that oncologists are planning to limit, or are considering limiting, their participation in trials because NCI's reimbursement is inadequate. Although they were issued in April, the two reports continue to reverberate throughout the cancer community. John Mendelsohn, M.D. , president of the M. D. Anderson Cancer Center in Houston and chair of the IOM panel, spoke about the recommendations in press briefi ngs and oral sessions at the annual meetings of ASCO and the American Association for Cancer Research. Outgoing NCI director John Niederhuber, M.D., who commissioned the report, went further. He recommended to the National Cancer Advisory Board in June that the cooperative group system be scrapped and replaced by a system based on the NCI-funded cancer centers. Richard Schilsky, M.D., a longtime leader in the cooperative group system and an IOM panelist, responded publicly that this was not a good idea and that all the IOM recommendations should be implemented soon. Cooperative groups continued to be in the oncology news with an announcement that three of the groups would merge some administrative functions — a development in line with IOM recommendations but predating the report, they said. And incoming NCI director Harold Varmus, M.D., in his fi rst town hall meeting with staff, named the clinical trials system as one of several areas that were "obviously dysfunctional" and needed repair. Meanwhile, innovative trial designs, based on patient biomarkers, are attracting attention as ways to streamline and speed up trials ( see accompanying news stories). I interviewed Mendelsohn in May about the IOM report — A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program — and what he thinks needs to be done to improve the cancer clinical trial system. JN: The IOM report was issued at the same time as the ASCO survey. With a new director scheduled to be appointed, was the timing a coincidence? JM: The IOM report was commissioned a year ago by NCI director Dr. John E. Niederhuber, over concerns about the program's ability to maintain the progress they have produced. I hope that when the new director addresses the report, he will see it as helpful and accept our recommendations. It may allow the new head of the NCI to get cracking and not waste time with another review. [ Editor's note: the interview occurred before a new director was named. ] JN: Your report found that the NCI's review process delays launching a clinical trial. The NCI reports that 56% of phase III clinical trials took more than 2 years to start. How can the speed and effi ciency of the design, launch, and conduct of clinical trials be improved? JM: The entire process must be streamlined so we can implement ways to do it more effi ciently. The NCI has redundant review procedures that add to reviews by the cooperative groups, the intergroup scientifi c review committee, the Food and Drug Administration [FDA], etc. As modifi cations are made, protocols must be recycled again and again. All of this only serves to delay the launch of a clinical trial. The prime task should be to get an innovative, high-priority trial approved in a shorter period of time with adequate reimbursement for time and effort, adopting best practices for effi cacy and safety. Right now, the NCI, the FDA, the cooperative groups, pharmaceutical and biotech companies, and academic and community medical groups are looking at the shared goal of developing new drugs against cancer through different lenses with different agendas. If we could get all of the various people who have an interest in clinical trials and lock them in a room, we'd get lots of work done quickly and have a better trial. We are all going to have to do some giving because there is such a great opportunity today to exploit our capacity to select new drugs and antibodies that target the genetic abnormalities expressed in an individual patient's cancer.


A device designed for the measurement of limb volume. It consists of two sets of light-emitting diodes and photosensors arranged as parallel-acting light curtains. The transmitters are set in a frame, perpendicular to each other, so that as the frame passes over the limb the limb is illuminated and its diameter is measured in two planes.


A novel tight-binding method is developed, based on the extended Huckel approximation and charge self-consistency, with referring the band structure and the total energy of the local density approx...


effective supports students? And how do effective teachers interact with their students to promote the best opportunities and results for all? In Qualities of Effective Teachers, 3rd edition, James H. Stronge explores these questions and more as he synthesizes the literature on teacher effectiveness. The result? A research-based framework for effective teaching that addresses: • Professional knowledge • Instructional planning • Instructional delivery • Assessment • Learning environment • Professionalism Stronge also examines characteristics of effective teachers of at-risk students and high-ability students. To bridge the gap between research and practice, he includes checklists of skills and positive qualities associated with effective teacher performance as well as red flags that indicate that teachers may not be reaching their full potential in the classroom. This resource is for any educator interested in improving teaching. It offers research-based advice for teachers who wish to improve their own performance, as well guidance for teacher leaders and supervisors, school administrators and department heads, staff development specialists, teacher and administrator educators, human resource specialists, and education policymakers and their staffs. Anyone who has a vested interest in students and their success can gain valuable insight and practical tools to ensure positive outcomes for all students. New to the 3rd edition: positive effective teachers, domains ReferencesWith the rapid changes in the social, political, economic and technological landscape today's learners face a more globally competitive job market after leaving school. The 21st century, which is characterized by the emergence of knowledge-based societies, expects learners to be comfortable in dealing with ambiguities and complexities in the real world and to be able to use knowledge as a tool at their workplace. This book will help readers develop an in-depth understanding of freedom jazz musicians enjoy in making music together, we can better understand how Christian freedom might be enacted in daily life. If Western churches discover and enact Christian freedom in a meaningful way, the songs that they improvise will be as siren calls to people in chains.A valuable and documented source. --Choice Ferkiss has navigated an exceedingly complex course through our philosophical history, tracing the lineage of ideas about nature and technology as they evolved from ancient times through Taoism, industrialism, Marxism, and several other `isms.'Offers a colorful, concise, and well-written survey of formal thought on the role of science and technology. --Policy Currents Worldwide in its scope and reach, Ferkiss's book encompasses ethics and technology, society, and international relations--a true renaissance perspective. It is written clearly and without trepidations. --Amitai Etzioni, author of The Moral Dimension A valuable overview of conceptions of nature, science, and technology since ancient times. Anyone concerned with global environmental issues will benefit from its temperate, even- handed treatment of the hundreds of thinkers who have participated in great age-old debate over the human conquest of the earth and its resources. --W. Wagar, Teaching Professor, A fine book . . . an excellent source book [and] a valuable reference work, one of those books that belong on the shelf, near at hand, in the collection of any serious student of environmentalism and the history of technology. It will be consulted often. --Walter Rosenbaum, University of Florida, author of Environmental Politics and Policy An extraordinary achievement--a dazzling scholarly tour de force that is so clearly and elegantly written that readers are gripped by the superb story [Ferkiss] tells. It is the story of what may be the central issue of our time--humanity's relationship with nature. . . . Perhaps no scholar on earth is better equipped to tell this story. . . . [Ferkiss] exhibits an extraordinary command of the subject as he takes readers on a fascinating guided tour through Western and Eastern culture, beautifully summarizing and judiciously commenting on the changing attitudes shown by people ranging from Buddhists to Nazis, from the ancient Greeks to today's explores the development implications of India's seventy years (1947-2017) of socio-economic policy regimes. It discusses structural dualism and the digital divide, which it identifies as the major socio-economic structural elements of the Indian economy, along with the external forces of globalisation. Since the adoption of comprehensive economic reforms in 1991, India has been liberalising its economy, due in part to the rising pressures of globalisation. However, critics have argued that Indian liberalisation policy has aggravated unemployment, regional inequality and poverty, and also increased India's external vulnerability. This book tests the validity of these arguments, and provides readers a deeper understanding of the structural and institutional elements of the articulation of Indian society. It also examines the paradoxical political and economic effects of the information and communication (ICT ) industry in India, due to the economic disparities between the beneficiaries of the ICT windfall and those unable to reap those benefits. Lastly, by investigating the integration of key traditional sectors into modern sectors, the book provides policy suggestions for tackling the sectoral and segmental disarticulation that currently characterises Indian society.As interactive application software such as apps, installations, and multimedia presentations have become pervasive in everyday life, more and more computer scientists, engineers, and technology experts acknowledge the influence that exists beyond visual explanations. Computational Solutions for Knowledge, Art, and Entertainment: Information Exchange Beyond Text focuses on the methods of depicting knowledge-based concepts in order to assert power beyond a visual explanation of scientific and computational notions. This book combines formal descriptions with graphical presentations and encourages readers to interact by creating visual solutions for science-related concepts and presenting data. This reference is essential for researchers, computer scientists, and academics focusing on the integration of science, technology, computing, art, and mathematics for visual problem solving.Of late, farming community in India has been facing new challenges of food and nutrition security, human health and structural adjustment to comply with WTO stipulations on the one hand and sustainable environment on the other. The overuse of fertilizers and chemicals, and depleting water resources are essentially threatening the sustainability of Indian agriculture. The slow growth of agriculture sector mainly due to stagnation in productivity growth is a grave concern for policy-makers and development planners. The leading introductory text, this authoritative volume comprehensively describes the school psychologist's role in promoting positive academic, behavioral, and emotional outcomes for all students. The book emphasizes a problem-solving- based, data-driven approach to practice in today's diverse schools. It grounds the reader in the concepts and tools needed to become a competent, ethical practitioner; implement and evaluate multi-tiered interventions; and facilitate systems-level change. Useful pedagogical features include illustrative vignettes and end-of-chapter discussion questions and activities"--The fourth edition of an authoritative overview, with all new chapters that capture the state of the art in a rapidly growing field. Science and Technology Studies (STS) is a flourishing interdisciplinary field that examines the transformative power of science and technology to arrange and rearrange contemporary societies. The Handbook of Science and Technology Studies provides a comprehensive and authoritative overview of the field, reviewing current research and major theoretical and methodological approaches in a way that is accessible to both new and established scholars from a range of disciplines. This new edition, sponsored by the Society for Social Studies of Science, is the fourth in a series of volumes that have defined the field of STS. It features 36 chapters, each written for the fourth edition, that capture the state of the art in a rich and rapidly growing field. One especially notable development is the increasing integration of feminist, gender, and postcolonial studies into the body of STS knowledge. The book covers methods and participatory practices in STS research; mechanisms by which knowledge, people, and societies are coproduced; the design, construction, and use of material devices and infrastructures; the organization and governance of science; and STS and societal challenges including aging, agriculture, security, disasters, environmental justice, and climate change.This book reviews the extraordinary promise of technological advances over the next twenty years or so, and assesses some of the key issues -- economic, social, environmental, ethical -- that decision-makers in government, business and society will face in the decades ahead.For courses in Science, Technology, and Society; Culture and Society; Sociology; Ecology; Technology and Ethics; Technology for the Future; Local/Global Student Responsibility for the Future; Technology and Education; New and Emerging Technologies; and Implications of Engineering for the Future. Unique in its depth, breadth, and variety of opinions and writings, Technology and Society, Third • A • Book In face face with the solutions to book been the major with many the have made to into the society. The development and implementation of information communication technology (ICT) devices and policies within various of service have significantly aided in the infrastructural progression of these countries. these


Considerable amounts of allochthonous material of eolian-aerial provenance have been discovered in mountain forest soils of the Southern Urals; they were identified by the absence of some minerals (f.e. talc, 2M 1 biotite, quartz) in the parent rock, as well as by kaolinite predominance in soils on quartzites. The occurrence of such soils on the hilltops provides for exclusive eolian-aerial transfer to material and its deposition as a mantle upon all the topographic elements. Accumulation is more advanced in forests. In order to determine mica and chlorites polytypes, the method of X-ray scanning of textures inverse space has been applied, which permits registering the diffraction maxima of various zones when the nonbasal reflexions get increased.


Heparin‐binding EGF‐like growth factor (HB‐EGF), which belongs to the EGF‐family of growth factors, was isolated from the conditioned medium of macrophage‐like cells. To investigate the effect of N‐ and C‐terminal residues of the EGF‐like domain of HB‐EGF in the binding affinity to the EGF receptor on A431 cell. We synthesized HB‐EGF(44–86) corresponding to the EGF‐like domain of HB‐EGF and its N‐ or C‐terminal truncated peptides. Thermolytic digestion demonstrated three disulfide bond pairings of the EGF‐like domain in HB‐EGF is consistent with that of human‐EGF and human‐TGF‐α. HB‐EGF(44–86) showed high binding affinity to EGF‐receptor, like human‐EGF. The truncation of the C‐terminal Leu86 residue from HB‐EGF(44–86), HB‐EGF(45–86) or HB‐EGF(46–86) caused a drastic reduction in the binding affinity to the EGF receptor. These results suggest that the EGF‐like domain of HB‐EGF plays an important role in the binding to the EGF receptor, and its C‐terminal Leu86 residue is necessary for binding with the EGF‐receptor. In addition, the deletion of the two N‐terminal residues (Asp44‐Pro45) from HB‐EGF(44–86) caused a 10‐fold decrease in relative binding affinity to the EGF receptor. This indicates that the two N‐terminal residues of the EGF‐like domain of HB‐EGF are necessary for its optimal binding affinity to the EGF receptor. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd.


Ascorbate reacts with S-nitrosothiols generally, in the pH range 3–13 by way of two distinct pathways, (a) at low [ascorbate], typically below ≈1 × 10−4 mol dm−3 which leads to the formation of NO and the disulfide, and (b) at higher [ascorbate] when the products are the thiol and NO. Reaction (a) is Cu2+-dependent, and is completely cut out in the presence of EDTA, whereas reaction (b) is totally independent of [Cu2+] and takes place readily whether EDTA is present or not. For S-nitrosoglutathione (GSNO) the two reactions can be made quite separate, although for some reactants the two reactions overlap. In reaction (a), ascorbate acts as a reducing agent, generating Cu+ from Cu2+, which in turn reacts with RSNO forming initially NO, Cu2+ and RS−. The latter can then play the role of reducing agent for Cu2+, leading to disulfide formation. Ascorbate will initiate reaction when the free thiolate has initially been reduced to a very low level by the synthesis of RSNO from a large excess of nitrous acid over the thiol. Reaction (b) is interpreted in terms of nucleophilic attack by ascorbate at the nitroso-nitrogen atom, leading to thiol and O-nitrosoascorbate which breaks up, by a free-radical pathway, to give dehydroascorbic acid and NO. A similar pathway is the accepted mechanism in the literature for the nitrosation of ascorbate by nitrous acid and alkyl nitrites. The rate constant for the Cu2+ -independent pathway increases sharply with pH and analysis of the variation of the rate constant with pH identifies a reaction pathway via both the mono- and di-anion forms of ascorbate, with the latter being the more reactive. As expected the entropy of activation is large and negative. Some aspects of structure–reactivity trends are discussed.


sterile product facility design and project management second edition book by crc press are a good way to achieve details about operating certainproducts. Many products that you buy can be obtained using instruction manuals. These user guides are clearlybuilt to give step-by-step information about how you ought to go ahead in operating certain equipments. Ahandbook is really a user's guide to operating the equipments. Should you loose your best guide or even the productwould not provide an instructions, you can easily obtain one on the net. You can search for the manual of yourchoice online. Here, it is possible to work with google to browse through the available user guide and find the mainone you'll need. On the net, you'll be able to discover the manual that you might want with great ease andsimplicity


In an update of his seminal work, The Scientific Basis of the Art of Teaching, Mr* Gage discusses the growth of the "bodies of fairly well-confirmed knowledge" about teaching and its effects on student achievement? There is a scientific basis that can inform our knowledge of the teaching process, he says; we have only to act on it to begin to affect practice* TEACHING IS the central process in education. It comes after eco nomic resources, physical facili ties, and curriculum have been determined, and it is intended to lead to ward learning. It is the social function through which societies foster achieve


ABSTRACT Supercritical flow with sediment transport is a common phenomenon in steep rivers. This kind of flow presents features not present in rivers flowing in subcritical conditions. The development of a mathematical model to simulate supercritical flow with sediment transport in sandy rivers is described. The model is based on a numerical scheme for the integral version of the full governing equations and takes into account bottom configurations.


Hollow spherical concrete slab has been one of alternative technology
aimed to reduce the self-weight and save concrete material. The plastic ball
placement on concrete tension area should not to reduce flexural strength. The
non linear concrete material and the presence of plastic balls inside the slab lead
to the necessity of numerical solution approach using ATENA software.
This research deals with flexural behavior of 12 cm-thick-solid slab (PL1)
and two hollow sphere slabs with thickness of 12 cm (PL2) and 14.3 cm (PL3),
which are casted onsite, employing non linear finite element method. The test
setting and specimen data refer to previous experimental research by Soeharno
(2009). Two-point static load testing was applied to the specimen and given by a
hydraulic jack. Research parameter study observed the effect of slab void ratio on
its flexural behavior. Numerical analysis was performed using ATENA software
and supported by GID as the graphical user interface. The observed behaviors on
this research are strength, stiffness, ductility, and crack pattern.
The determination of numerical modeling element affects the analysis
result. The comparison of element type indicates that flexural strength of
hexahedral solid slab (PL1_NumLH) is closer to experimental result (PL1_EKS)
than that of tetrahedral solid slab (PL1_NumLT). This research shows that
flexural strength of numerical calculation of PL1_NUM, PL2_NUM, PL3_NUM,
are respectively 54 kN, 53 kN, and 67 kN. Whereas, the flexural strength obtained
by experiments of PL1_EKS, PL2_EKS, PL3_EKS, are respectively 43.29 kN,
46.29 kN, and 68.29 kN. Such flexural strength differences occur because of the
ideal condition of numerical modeling. Flexural strength, stiffness, and ductility
of PL2_NUM (PB19) decrease as the slab void ratio increases.


This study aims to determine the relationship between family support and student career decision making. This research was conducted at SMK Negeri 1 Binjai in class XI. This research includes quantitative research with correlational methods. The data collection technique is in the form of a questionnaire (questionnaire). The population of this study amounted to 266 students. The sample of this study amounted to 40 students. The sampling technique was done randomly. The results showed that from the results of the product moment correlation analysis hypothesis test of 0.942 > 0.312, it can be concluded that the null hypothesis (Ho) is rejected and (Ha) is accepted, it shows that there is a very strong relationship between family support and student career decision making.at SMK Negeri 1 Binjai.