The bachelor thesis deals with responsibilities in public administration. The first part is devoted to the interpretation of concepts of public power, public administration, public budgets, liability and liability for damage. This is followed by an analysis of the current legislation on liability for damage caused by public authorities. In the practical part, the bachelor thesis deals with selected court decisions of the European Court of Human Rights and compares its impact with compensation statistics. The aim of the practical part is to analyze the decisions of the European Court of Human Rights, which influence the drafting and interpretation of Czech legislation in the area of liability for damage caused by the exercise of public authority and to outline possible future impacts on public budgets.


This paper presents a noncontact force calibration method in applications of the dual-probe nanotweezer. A 2 DOF mechanical lever has been developed to directly calibrate both the normal and lateral sensitivities of two optical levers used to independently measure normal and lateral forces applied on the nanotweezer. The mechanical lever is designed with a configuration of two mutually perpendicular levers, each consists of two flexible hinges, sharing a same rotational center, Each lever can convert the translation into a nanoscale rotation angle that provides an accurate conversion between the photodiode voltage output and deflective angle of a cantilever. During the calibration, a cantilever is mounted on the mechanical lever and attached on the rotational center of the flexible hinges. By making use of its nanomotion on the Z-axis and using an external motion on the barrier, this device can complete the local and full-range sensitivity calibrations of the optical levers without modifying the actual AFM or the cantilevers. Nonlinearities on both normal and lateral of the optical levers have been accurately compensated.


This paper briefly introduces the usage of one-component polyurethane adhesive glass in the bus windows glass installation,explains the entire process specifications and process of the pre-treatment and coating. And the author proves that this technology can effectively improve the coating quality to better meet the quality requirements.


Multiuser, Multiple Input, Single Output (MU-MISO) systems are proving to be indispensable in the next generation wireless networks such as 5G and 6G. The spatial diversity of MISO systems have been leveraged in physical layer designs in these wireless systems to improve the capacity. Several recent studies have utilised redundancies in the content request along with the spatial diversity of a MISO system to improve the capacity further. It is shown that Max-Min Fair (MMF) Beamforming schemes for MISO based on SDMA, NOMA, OMA and Rate-Splitting could be used to improve the content delivery rates. However, in most of these studies the key aspects such as the queueing delays in the downlink and the user dynamics have generally been ignored. In this work, we study how the interplay between queueing, beamforming and the user dynamics affects the Quality-of-Service (user experienced delay) of downlink in MU-MISO content centric networks (CCNs). We propose queueing theoretic models that are simple in nature and can be directly adapted to MU-MISO CCNs to perform optimal multi-group multicast downlink transmissions. We show that a recently developed Simple Multicast Queue (SMQ) for SISO systems can be directly used for MU-MISO systems and that it provides superior performance due to its always-stable nature. Further, we observe that MMF Beamforming schemes coupled with SMQ can be quite unfair to users with good channels. Thus, we propose an improvement to SMQ called Dual SMQ which addresses this issue. We also provide theoretical analysis of the mean delay experienced by the users in such MU-MISO CCNs.


In order to know the energy absorption property of rubber,experimental study on dynamics of three kinds of rubber with different formula was carried out by Split Hopkinson Pressure Bar test,the stress-strain curves under different strain rates were compared.The results show that dynamic young′s modulus,peak stress,energy absorption rate increase with strain rates increasing.The low stiffness rubber has obvious dynamic strain-rate effect,the addition of reinforcing agent and softener can greatly improve the energy absorption rate of rubber.


The primary mode of premature failure for near-surface mounted strengthened beams is the concrete cover separation. Due to its complexity, most of the prediction methods for concrete cover separation tend to be empirical based, which can limit their usage to specific near-surface mounted strengthening configurations. In response to that, this article presents a mechanics-based design which uses the moment-rotation approach and the global energy balance approach which is less reliant on empirical formulations, as the mechanics of reinforced concrete beam such as tension stiffening and propagation of concrete cover separation debonding crack are directly simulated rather than empirically derived. The proposed design procedure was validated against published experimental results of reinforced concrete beams strengthened with near-surface mounted carbon fibre–reinforced polymer bars, near-surface mounted carbon fibre–reinforced polymer strips or side-near-surface mounted carbon fibre–reinforced polymer bars and show good accuracy. As it is less reliant on empirical formulations, the proposed design procedure should be applicable to various near-surface mounted reinforcement configurations and materials.


The refractive index profile measurement is desirable for fabricating and characterizing fibres. The fast Fourier transform method (FFT) and phase-shifting interferometry (PSI) were used to determine the refractive index profiles of polypropylene (PP) fibres. Interference fringe patterns produced by Mach–Zehnder interferometer have been analysed using the suggested methods. Wrapped phase maps and contour lines of the obtained fringes were produced. The methods used are relatively simple, accurate and are capable of conducting fully automatic measurement of refractive index profiles for fibres. By comparing the obtained refractive index profiles using the two methods, it is found that there is good agreement between them and also with the literature.


Solution-focused brief therapy (SFBT) utilizes the client's strengths and resources to the fullest to achieve what the client wants, rather than looking at the client's problem pathologically and digging deeper into analysis. Therefore, in this article, we would like to introduce a SFBT that can be usefully applied to the education and counseling of diabetic patients in the clinical field. Pre-session change questions, rewarding questions, miracle questions, exception-finding questions, scaling questions, relationship questions, and coping questions used in SFBT consist of the questions that allow the client to answer positively. In this process, a medical social worker pays full attention to remarks that suggest clues to the client's potential for change, the change the client wants, past experiences that have been successful, and what has already been attempted to make the situation better. Also, when setting goals, it's important to target positive behaviors rather than eliminate the problem and what's important to the patient and small, specific, clear, and actionable things. SFBT no longer focuses on or talks about the client's problem. The client has the resources and strengths to solve the problem. Rather than exploring the cause of the problem, it is important to find a clue to the solution and connect it to actual action, so you can use the solution question techniques to get the client to practice using their strengths. In the treatment field, we recommend that the client remember and ask a few questions with the belief that they can solve them on their own.


We prove that the exponent of distribution of $\unicode[STIX]{x1D70F}_{3}$
 in arithmetic progressions can be as large as $\frac{1}{2}+\frac{1}{34}$
 , provided that the moduli is squarefree and has only sufficiently small prime factors. The tools involve arithmetic exponent pairs for algebraic trace functions, as well as a double $q$
 -analogue of the van der Corput method for smooth bilinear forms.


This paper analyzes the geo-environmental factors effecting on the human stature,which were implemented in 102 populations(23 Han nationalities and 79 minority nationalities) distributed in 16 prefectures in China,using GIS spatial analysis function and the cartography method for the first time.The study results show that(1) The human body height increased with the latitude value increasing;(2) The human body height increased with the increasing of solar effective radiation;(3) the human population stature in region with higher rainfall and the higher percentage relative humidity is lower than other regions;(4) the average wind speed is a positive factor to the population stature;(5) the research results showed that the altitude value and air pressure value have no significant effect on human body height.Finally,it demonstrated that the GIS tools and function have great benefit to the human body growth research and it is a renovation among disciplinary intersection.


An important quest for the life science community is to deliver a complete annotation of the human building-blocks of life, the genes and the proteins. Here, we report on a genome-wide effort to annotate all protein-coding genes based on single cell transcriptomics data representing all major tissues and organs in the human body, integrated with data from bulk transcriptomics and antibody-based tissue profiling. Altogether, 25 tissues have been analyzed with single cell transcriptomics resulting in genome-wide expression in 444 single cell types using a strategy involving pooling data from individual cells to obtain genome-wide expression profiles of individual cell type. We introduce a new genome-wide classification tool based on clustering of similar expression profiles across single cell types, which can be visualized using dimensional reduction maps (UMAP). The clustering classification is integrated with a new "tau" score classification for all protein-coding genes, resulting in a measure of single cell specificity across all cell types for all individual genes. The analysis has allowed us to annotate all human protein-coding genes with regards to function and spatial distribution across individual cell types across all major tissues and organs in the human body. A new version of the open access Human Protein Atlas (www.proteinatlas.org) has been launched to enable researchers to explore the new genome-wide annotation on an individual gene level.


This paper summarizes modification study process of mesoporous molecular sieve at home and abroad,such as organic ion exchange modification,dealuminum modification,miscellaneous atomic crystal replacement modification,pore and surface modification.Reviewed on various modification method and principle,which provides a new method for the application filed of new inorganic material molecular,and development direction of molecular sieve in the future is prospected.


It is shown that the distribution of normal stress around a craze, found by Knight using a Fourier transform method may not be uniquely determined, and that in fact the stress field cannot be computed unless the rheological properties of the craze tip material are known.


Recombinant adeno‐associated virus (AAV) is currently the most widely used platform for in vivo gene therapy. Clinical pharmacology is a central field for AAV gene therapy, represented by the pillars of pharmacokinetics, pharmacodynamics/efficacy, and safety. In this review, we provide a comprehensive summary of clinical pharmacology considerations for recombinant AAV. The main topics covered are biodistribution and shedding, dose–exposure–response relationship, safety, immune and stress response, and clinical dose selection strategies. We highlight how the cumulative knowledge of AAV gene therapy could help with guiding clinical trial design and assessing and mitigating risks, as well as planning and executing pharmacokinetic/pharmacodynamic /safety data analyses. In addition, we discuss the major gaps and areas of growth in clinical pharmacology understanding of recombinant AAV. These include the mechanisms of the durability of treatment response and variability in biodistribution, transduction, and immunogenicity, as well as a potential influence on AAV's safety and efficacy profiles by drug product characteristics and patient intrinsic/extrinsic factors.


More than 40% of the world's population selects agribusiness as their primary occupation. Agribusiness has recently seen growth in the development of autonomous vehicles, including robots. When using a traditional farming strategy, the equipment used to carry out different tasks is expensive and poorly suited for handling. In this manner, Farmers must use cutting-edge machinery to conduct farming procedures. The proposed project intends to strengthen the robot. The robot is capable of seeding, ploughing, planting, mowing the lawn, and watering. The suggested robot uses solar energy for electricity. The need for any photovoltaic panels is an unnecessary external power source. The robot will reduce the cost of the work, speed up the process, and also improves the accuracy of the work. The energy utilized by the device is less when compared to tractors or other farming machinery devices such as electric pumps.


Pavement marking retroreflectivity decreases when conditions are wet, meaning marking visibility is worse under these hazardous conditions. There is widespread desire for a pavement marking system that can provide good wet retroreflectivity with an acceptably long lifetime at acceptably low cost. Several previous studies have shown that waterborne paint with the right type of drop-in optics can be a very cost effective approach to wet retroreflectivity. This study provides a detailed comparison of long term durability of wet retroreflectivity performance of waterborne paint with various bead packages. It has been found that using a high quality waterborne acrylic-based traffic paint in combination with a mix of small and large round glass beads can provide exceptional levels of wet retroreflectivity for at least a year even on a high traffic road in a cold, northern climate. The systems described in this report may provide asset owners with significant improvements in safety with minimal change in overall system cost.


A study was undertaken to evaluate the effect of operating line throttling on inlet-arc noise from high speed fans. Experimental measurements on a 1/4-scale fan stage tested in an anechoic chamber, with and without inlet turbulence control devices, were utilized to assess the effect of constant speed throttling on the forward arc radiated noise characteristics. Different effects were observed in different speed ranges with different types of inflow turbulence control. These effects were correlated with some of the current theories on fan noise generation mechanisms, and partial success was achieved in attempting to relate the various theoretical models to the observed trends. The results of this study have an important bearing on estimating the noise characteristics of new fan designs from scaling the measured characteristics of previously tested fans.


The Chair for Food Process Engineering and Dairy Technology at the Technical University of Munich in Freising-Weihenstephan has been installed since 1992 in a new building hosting modern and well-equipped laboratories and pilot-plant facilities. Its objectives in terms of research are to participate in the development of the scientific understanding of complex food systems and their constitutive components, and the way they interact with the process during manufacturing. The aim is to allow the production of food products with desired properties, improved quality and optimal safety, while ensuring an efficient use of raw materials and of the energy required for industrial production. The methodology used involves the fractionation of complex systems and the systematic study of their constitutive components taken in isolation as well as in various combinations. Milk, as a naturally complex raw material, receives particular attention, but research activities increasingly extend to other functional food substrates such as eggs. The research activities are organized into three working groups that reflect the core competencies developed at the chair throughout the years: Bio-Processes and Aseptic Processing, Formation of Structures in Food Systems, and Protein Technology. Its key position within the 'Centre of Life and Food Science' of the Technical University of Munich fosters interdisciplinary interactions with many specialized scientists, and therefore provides a broad perspective regarding the comprehension of the complex implications of modern food and pharmaceutical product manufacturing.


ed from: The Second Scientific Meeting of the Confer'ence on the therapetrtic uses of /itarnin A acid, held on January 27, 28, 29, 1975, in Elinis, Switzerland.


Investor-state dispute settlement relies heavily on the production of evidence. Evidence is certainly a necessary condition for a fair trial, but is it sufficient? Instances of 'guerrilla tactics' and non-substantiated claims are increasingly common. In a world of costly litigation, the availability of appropriate and reliable evidence is crucial for avoiding accusations of ideologically-driven decisions and achieving a 'fair and equitable' resolution of a dispute. Against this background, the present article uses an interdisciplinary analysis drawn from contract theory and transaction cost economics to explore the potential of two evidentiary tools for the disclosure of material information: adverse inferences and penalty default rules. The article shows that penalty default rules can be a valuable complement to adverse inferences, as they allow for the strategic interpretation of inherently incomplete treaty standards, thus attaching concrete legal consequences to the denial of a party to disclose material evidence to the tribunal.


The World Meteorological Organisation programme, Global Atmospheric Watch (GAW), is designed to observe long-term changes in atmospheric composition. Measurement stations from around the globe contribute to this network of observations; many small observatories measure only one or two atmospheric components, but a core, 29 worldwide, have committed to a much more extensive measurement programme - these are referred to as the GAW 'Global' observatories. They are scattered across every continent and on remote oceanic islands and are operated by both developed and developing countries making this a truly international effort.

In May 2013, Halley station was awarded GAW Global status - only the second UK observatory to achieve this accolade. This status was awarded because of the on-going commitment to measurements of reactive trace gases, greenhouse gases, and total ozone. These GAW data are submitted to publicly-accessible databases, from where they will be used to derive annual assessments of the "health" of the atmosphere, and to test global numerical models of the atmosphere.


It is widely accepted that increased city size brings greater industrial diversification. Nevertheless the results presented in studies which have tested this assertion are somewhat inconclusive, since doubts arise concerning the fitness of the methods used to express industrial diversification in quantitative terms. This paper reviews certain features of existing methods, describes two measures which are believed to meet certain


Background: Malocclusion is a common oral health problem. Orthodontic treatment is needed to treat malocclusion so that the teeth can achieve a good occlusion. The need for orthodontic treatment and the outcome can be measured using an orthodontic index. One of the orthodontic indexes that can measure the need for orthodontic treatment and the outcome is ICON index. Purpose: To find out the level of need and changes in the outcome of orthodontic treatment in the RSGM-P FKG USAKTI's orthodontic clinic based on the ICON index. Method: This research is a descriptive observational study with a cross-sectional design. Examination and measurement of the study model of patients aged 8 – 12 years old who came to the orthodontic clinic of RSGM-P FKG USAKTI in January 2018 – December 2019 was carried out based on the ICON component. a score was given based on the condition of the teeth in the study model. Result: the assessment of 48 patients showed that 36 patients (75%) were categorized as needing orthodontic treatment and 12 patients (25%) were categorized as not needing orthodontic treatment. Treatment result were assessed with improvement level. It was found that no subject was categorized as greatly improved, 5 patients (10,42%) were categorized as substantially improved, 15 patients (31,25%) were categorized as moderately improved, 15 patients (31,25%) were categorized as minimally improved, and 13 patients (27,08%) were categorized as not improved/worst. Conclusion: The research results illustrate that most of the patients treated at the orthodontic clinic RSGM-P FKG USAKTI require orthodontic treatment and the improvement level are mostly categorized as moderately improved and minimally improved.


In this study, physical and mechanical properties of lightweight concrete mortars produced with pumice lightweight aggregate cured in autoclave were investigated. In the production of concrete mortar, pumice aggregate of in size of 0-4 mm which was taken from Isparta, Turkey was used. The cement content and ratio of water/cement were kept 300 kg/m 3 and 0.15, respectively. The specimens were demoulded and they were exposed to pressure steam curing in 2, 4, 6, 8 and 10 hours after 24 hours. Furthermore, separate specimens were produced in same properties for air and water cure at 7 and 28 ages. On the specimens, compressive strength, bulk density, specific porosity and water absorption were tested. The results obtained from pressure steam curing were compared with specimens cured in air and in water. It was observed that by curing of specimens in the pressure steam at 8 hours, they have the best physical and mechanical properties when compared with specimens cured in air and in water.


The invention relates to compounds of formula (I), IN WHICH THE MEANING OF different substituents includes, among others, R1 is H or alkyl of 1 to 8 CY M is OOS, processes for their preparation, pharmaceutical compositions CONTAINING and their use as inhibitors of 5 alpha-reductase TREATMENT TO REDUCE THE SIZE OF THE PROSTATE.


Signaling by two classes of endoplasmic reticulum (ER) Ca2+ stores was studied in primary cultured rat astrocytes. Cytosolic and intra‐ER Ca2+ concentrations ([Ca2+]CYT and [Ca2+]ER) were measured with, respectively, Fura‐2 and Furaptra, in separate experiments. The agonists, glutamate and ATP, released Ca2+ primarily from cyclopiazonic acid (CPA)‐sensitive ER Ca2+ stores (CPA inhibits ER Ca2+ pumps). Agonist‐evoked release was abolished by prior treatment with CPA but was unaffected by prior depletion of caffeine/ryanodine (CAF/RY)‐sensitive ER Ca2+ stores. Conversely, prior depletion of the CPA‐sensitive stores did not interfere with Ca2+ release or reuptake in the CAF/RY‐sensitive stores. Unloading of the CPA‐sensitive stores, but not the CAF/RY‐sensitive stores, promoted Ca2+ entry through "store‐operated channels." Resting [Ca2+]ER averaged 153 μM (based on in situ calibration of Furaptra: KD = 76 μM, vs 53 μM in solution). The releasable Ca2+ in both types of ER Ca2+ stores was increased by Na+ pump inhibition with 1 mM ouabain or K+‐free medium. Using high spatial resolution imaging and image subtraction methods, we observed that some regions of the ER (45–58% of the total ER) unloaded and refilled when CPA was added and removed. Other regions of the ER (24–38%) unloaded and refilled when CAF was added and removed. The overlap between these two classes of ER was only 10–18%. These data indicate that there are two structurally separate, independent components of the ER and that they are responsible for the functional independence of the CPA‐sensitive and CAF/RY‐sensitive ER Ca2+ stores. GLIA 31:15–28, 2000. © 2000 Wiley‐Liss, Inc.


The study provides a commentary on creativity and character education in physical education(PE) and presents a tutorial that aims to guide the teaching chrativity and character using sportcasting, Moon and Choi's(2010) creativity and character education used as a conceptual framework, in which they asserted that creativity and character are inter-connected. This study reconceptualize it as integrative teaching and learning process where students work together and solve problems -cooperative problem solving process- in PE. Educational experience of students' cooperative problem solving activities in PE are presented using sportacasting. Sportcasting in PE(Lee, 2011) is a class activity where students simulate sports broadcasting(e.g., students report, analyze, and comment on game play). Examples of why sportcasting is particularly prudent are provided by reference to studies reporting the outcomes of several empirical studies. Also this study provided step by step approach to practice sportcasting activity in PE.


The technical quality of an IEEE Standard and its expeditious delivery to the user community are the responsibility of highly competent professionals, working in committee, to achieve these results. In a way, these goals are competing forces. Rushing a Standard by sacrificing quality is unacceptable, yet it is equally unacceptable to miss a market niche by delivering a Standard too late. That is why the BEE, as the best-equipped standards developer in the electrotechnology field, must continue to strive for improvements in our processes. A number of years ago, the IEEE Standards Department set about designing a user-friendly, automated system which would speed up the standards development process. We are now committed to this project, which we have called the Standards Process Automation System, or SPAsystemm for short. When fully implemented, we expect it to introduce economies, shorten schedules, lighten the load on our volunteers, and expand international participation. We started with certain assumptions: v Standards developers and end users have a variety of computer hardware and software and always will. v Users, potentially freed from the single view of data that characterizes paper distribution, might want to use and perceive the provided information in any number of ways. v High-quality electronic products must be affordable to produce. v No additional labor can be demanded of the volunteers who write the standards or the staff who manage the process. To a large extent, these assumptions have determined the solutions we are developing. The Standard Generalized Markup Language (SGML) offers one means by which to accommodate these assumptions, and so has been an important piece of the SPAsystemTM from its inception. In short, the SGML (IS0 8879-1986) is a standardized computer language for describing the structure of information, without regard to the specific hardware being used. From a user's perspective, a wellexecuted SGML system offers the ability to handle text, graphics,


There are regional boundaries for the K-12 schools which are administratively designated for commuting. It is typically necessary to provide a community with possibility of dynamic evolution of educational ciruclation network in information age based on reforming the commuting circumstance that local educational environment developed for the continuing education with social sytems to develope a macro public domain to facilitate the existing educational institutions which is nationally essential strategy responding to the learning community for participants and residents in the place with multi-dimensions of the social context that has identified the educational disadvantages in lined with the digital divide based on the conceptual approach in terms of local economy and geographical context. The commuting structure reflecting educational organizations that provoke not only social movements but also communal groups consisting of three categories; 1)territory, 2)community, and 3)proximity. Each part has subdivisions characterizing the main socio-physical attributes such as distance, cycle and accessibility. The educational network of collaborative learning depending on the social structure relating to local distribution and micro circulation in terms of group proximity can be examined by the educational interactions between subjective programs and physical accommodation arrayed along the potential circulation system to simulate variables of educational activities covering the national program, participatory education and active learning.


One of the goals of the accounting education and SBI-sponsored business assistance programs at this small AACSB-accredited university is to provide all students with direct, hands-on experience with small business accounting systems. To make the learning environment effective, the accounting faculty has undertaken a project to prepare an extensive series of video-based accounting system cases, using actual small businesses. Student teams' recommendations are shared with the operators of the businesses; follow-up reviews of instituted solutions may occur.


With continuing development of visual and network technology,network users demand a more sophisticated application mode than the 2D one,which further spurs the development of 3D web technology.The 3D shopping website is capable of objectifying and visualizing virtual products vividly,which satisfies users' needs for interactivity and tangibility.In this research,we attempt to combine the merits of 3DMax and WireFusion.The 3D interactive activities are generated in WireFusion,and then the 3D system is imbedded in Web page based on Java demon tools to realize the online function.The trial shows that the so developed 3D shopping website is feasible and practical and is very significant and useful for online browse and marketing.


Recently, extended gapless phases with emergent SU(2)$_1$ conformal invariance occupying finite regions in the phase diagrams have been found in one-dimensional spin-1/2 models with nonsymmorphic $O_h$ symmetry groups. In this work, we investigate the question of whether the conditions for emergent SU(2)$_1$ invariance can be loosened. We find that besides the nonsymmorphic $O_h$ group, the other four smaller nonsymmorphic cubic groups including $O$, $T_h$, $T_d$ and $T$ can also give rise to emergent SU(2)$_1$ invariance. Minimal spin-1/2 models having these nonsymmorphic cubic groups as symmetry groups are constructed, and numerical evidences for the emergent SU(2)$_1$ invariance are provided. Our work is useful for understanding gapless phases in one-dimensional spin systems with nonsymmorphic symmetries.


Advances in medical science that permit the artificial maintenance of circulation, respiration, and nourishment functions are forcing changes in the way the law looks at death. Historically, cardiopulmonary cessation was the sole criterion for determination of death.' Now, however, the vast majority of states supplement the cardiopulmonary test for death with a whole brain death standard, pursuant to which death is declared when there is irreversible cessation of all functions of the entire brain, including the brain stem.2 The condition of permanent vegetative state, as exists in the patient in a recent Wisconsin case' and as many as 25,000 other patients in the United States,4 is today pressing the law for yet another supplement to the legal definition of death. The absence of readily available and absolute diagnostic tests for determining whether a patient is in a permanent vegetative state, however, may render premature any consideration of neocortical brain death, or permanent vegetative state,5 in the legal definition of death. This article examines the development of the whole brain definition of death, the clinical realities of permanent vegetative state, case law treatment of decisions to withhold treatment from those in a permanent vegetative state, and a proposed Model Permanent Vegetative State Treatment Statute.


The effect of temperature on mobility (measured as distance traveled) of hermit crab Clibanarius aequabilis is describe in the present study. It was noted that the level of mobility increases when the temperature ranged from 18oC to 20o, but decreases when the temperature rised to 22oC.


PURPOSE: To shorten the waiting time of a memory read request in a request queue for which memory reference requests from respective instruction processors are stored in a storage controller in a multiprocessor system. CONSTITUTION: The storage controller(SC) 3 has the request queue stored with the memory reference requests from the instruction processors IP0 and IP1 to the SC in arrival order. The SC 3 preferentially selects and processes memory read requests in a principle and a request queue as to the IP0 and IP1 respectively and selects and processes a memory write request first only when the memory write request is present in the queue in the same area with the memory read request. When there is a conflict between memory reference requests to be processed from the IP0 and IP1, one memory reference request is selected according to the previously determined priority order. COPYRIGHT: (C)1993,JPO&Japio


The invention provides a browser and a browser bookmark data processing method. The method includes: acquiring the identification information of a user logging in the browser; transmitting the uploading request of the bookmark data corresponding to the user identification information to a cloud; performing internal memory decryption on the bookmark data file which corresponds to the user identification information and is saved by the browser after receiving an uploading response of the cloud, wherein the bookmark data file is generated by the browser encrypting the bookmark data; uploading the decrypted bookmark data to the cloud. By the method, the encrypted bookmark data can be saved on the browser side, the bookmark data can be uploaded after internal memory decryption, the user can directly download the bookmark data for use on other terminals, user use is facilitated, stealing of the local bookmark data is avoided, and the user can use the bookmark data conveniently without being affected by terminal changing or browser changing.


Lectin-like oxidised low-density lipoprotein receptor-1 (LOX-1) is a type E scavenger receptor found on the walls of endothelial cells, platelets, macrophages and smooth
muscle cells among others. Technologies for sensing and inhibiting LOX-1 are limited to poorly performing antibodies and genetic knockouts and despite significant
correlation with poor clinical outcomes, no LOX-1 modulation therapy has been tried in man. This thesis aims to establish whether 'Affimers'; new, small-size antibody
mimetics can be used in an assay platform to detect soluble forms of LOX-1 in solution and in the modulation of its function as an oxLDL receptor. The findings show that
Affimers can be used in combination with antibodies, or in complimentary binding pairs to develop a sensitive chemiluminescence based assay. Further, when used in a
concentration of 500ng/ml, Affimers can inhibit the early binding of oxLDL to LOX-1, in a controlled LOX-1 cellular expression system, though their effect is nulled after
prolonged incubation. Such findings along with other recently published evidence demonstrate that Affimers show great promise as diagnostic and therapeutic agents and there is enormous opportunity to develop the technology further from bench to bedside.


Cultivating mathematical exploratory ability in senior high school,we try to adopt the following ideas: 1.bring forward problems by means of observations and discovery;2.seek approaches of solving problems by means of guess and exploration;3.explain or prove practical problems;4.expand relevant problems by means of analogy and induction.


A Transcutaneous Energy Transmission System (TET) has been developed for the wireless energy transmission with two magnetically coupled coils. A resonance circuit is used to raise the induced voltage and current of the secondary coil. Its resonance frequency depends on the internal resistance of circuit and the transferred energy. Because the transferred energy usually changes in wide range, the output voltage is unstable and the energy transferring efficiency decrease. A push-pull class E amplifier is usedto generate high frequency AC voltage. To maintain proper resonance frequency, the voltage output of the amplifier was continuously monitored and adjusted to the optimized resonance frequency. Because of its high frequency (370 ㎑), a phase lockedloop circuit and a comparator are used to monitor the output waveform. The results of experimentaldata show that the PLL circuit can increase the transmission efficiency and stabilize the output voltage of TET.


Both autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED) and the rare thymoma patients with chronic mucocutaneous candidiasis (CMC) have neutralizing autoantibodies to Th17 cytokines and significant defects in production of IL‐22 and IL‐17F by their T cells. The cause of these defects is unknown. We hypothesized that they might result from autoimmunity against upstream cytokines normally responsible for generating and maintaining Th17 cells.


The biological focal region (BFR) induced by a single high-intensity focused ultrasound (HIFU) exposure is considered to be the foundation of the ultrasound ablation of tumor lesions. The purpose of this study was to explore the relationship between the acoustic focal region (AFR) and the BFRs with different combinations of power and time in low-power cumulative HIFU treatment. The finite-difference time-domain (FDTD) method was used to simulate AFR and BFR during HIFU ablation. The acoustic fields, the temperature profiles, and the shapes of BFRs were calculated by the Westervelt equation, Pennes' equation, and the equivalent thermal dose model. In order to verify the simulation rules, phantom and ex vivo bovine livers were exposed by HIFU with a different power and time. The results demonstrated that in the low-power cumulative HIFU treatment, when the lengths of BFRs and the length of AFR were approximately equal, the shape of the BFR induced by 'high power × short time' exposure was closer to that of AFR than the shape of the BFR induced by 'low power × long time' exposure, and the exposure energy required was significantly reduced. The analysis revealed the relationship between the BFR and the AFR with different acoustic power. This study provides a reference for doctors to determine power, time, and movement distance in clinical treatment.


Changes in mortality rates in Puerto Rico between 1765 and 1980 are analyzed by means of abbreviated transversal life tables. The 3 life table functions of life expectancy probability of dying and survivorship unlike some indicators are not affected by changes in the age structure. Puerto Ricos mortality experience can be divided into 3 subperiods: the Spanish era from 1765-1899 and 2 North American periods from 1899-1940 and from 1940-80. Mortality risks did not change much between 1765 and the end of the 19th century except in the 5-10 and 10-15 year cohorts which experienced declines of 59.8% and 56.6% respectively. Because of its poverty and technological backwardness Puerto Rico did not experience the improvements in nutrition medical technology or public health that brought mortality down in 19th century England and the US. During the 1st 4 decades of the North American presence on the island mortality risks declined by more than 20% for all ages under 65 and by more than 50% for those aged 5-25 years. The smallest reductions in mortality risks were among infants and those over 65. The greatest declines in probability of dying for all ages occurred in 1940-60 when the risk of dying was cut by more than 1/2 for the population under age 50. The decline in risks of mortality due to pregnancy and childbirth and the increase in mortality due to accidents homicide and suicide have combined to increase the gap between male and female risks of mortality. The proportion of the population surviving to specific ages increased steadily but very slowly between 1765 and 1899. 50% of the population survived to 22 years in 1765 while in 1894 50% survived to 29 years an increase of the median length of life of only 7.5 years. In 1902-03 50% of males and females respectively survived to ages 25.8 and 26.6 while by 1979-81 50% survived to ages 75.0 and 81.2. Life expectancy at birth in Puerto Rico increased from 28 years in 1765 to 32 years in 1894. From 1902-40 life expectancy increased by about 4 years/decade; from 1940-60 the change was 11 years/decade and since 1960 the increase has been less than 2 years/decade. Female life expectancy exceeded that of males by 1.2 years in 1902 and by 7.1 years in 1980. Life expectancy at birth in 1980 was 70.5 for males and 77.6 for females.


Because of an imbalance between computation and memory speed in modern processors, programmers are explicitly restructuring codes to perform well on particular memory systems, leading to machine-speciic programs. This paper describes a block algorithm for QR decomposition that is derivable by the compiler and has good performance on small matrices | sizes that are typically run on nodes of a massively parallel system or workstation. The advantage of our algorithm over the one found in LAPACK is that it can be derived by the compiler and needs no hand optimization.


INTRODUCTION: The motivation for developing the necessary methods and hardware for prostate imaging studies at ultra high magnetic fields originates from the promise of increased spatial, temporal and spectral resolution. Towards this goal, we have previously demonstrated the tradeoffs between an external 16 channel transmit-receive stripline array coil (trSAC) [1] and a transmit-receive endorectal coil (trERC) [2]. While the trERC provided a higher peak transmit B1 (B1+) and SNR, the trSAC provided a more homogenous B1+ in the region of the prostate resulting in more uniform contrast on T2w acquisitions. Ideally, the advantages of each coil could be combined to achieve the highest SNR on receive while maintaining a homogeneous B1 on transmit. Therefore, the focus of this paper is on the development and characterization of a new receive-only ERC (roERC) combined with the previously reported trSAC (roERC+trSAC).


The idea of the proposed measuring system is to synchronise robotised tacheometric measurements of an object with the existing relative displacements detected by a dilatometer. The system consists of a set of dilatometers, a robotised total station featuring ATR (automatic target recognition) and a dedicated software (Fig. 1). The software and a dilatometer were specially designed and built for the proposed system. The latter one uses Hall-effect sensors and magnets to detect and measure displacements (Fig. 5). Their output voltage is converted into digital signals and transmitted to a computer in which the displacement value is calculated by the software on the basis of the displacement-to-voltage characteristics (Fig. 7). They are precisely determined for each dilatometer during the calibration process, with help of splines, which is essential to ensure the high accuracy of measurements. The prototype of a dilatometer and its principle of operation are described in Subsections 2.1 and 2.2, while the calibration process is presented in Subsection 2.3. The dilatometers were subjected to laboratory tests to trial their operation and determine their accuracy. The results are given in Subsection 2.5. The dilatometers, apart from measuring the relative displacements, are also responsible for triggering the tacheometric measurement of object control points in ATR mode. Such a measurement is started up after exceeding the preset threshold values of displacement (Subsection 2.6). In this way the time synchronization of the relative and absolute measurements is achieved, allowing better assessment of the object deformation than in the case of measurements taken independently.


We have fabricated a multilayer structure consisting of a semiconductor-magnetic hybrid material GaAs:MnAs and GaAs/AlAs distributed Bragg reflectors, that is a one-dimensional semiconductor-based magnetophotonic crystal. Significant enhancement of magneto-optical effect was demonstrated at a controlled wavelength at room temperature. Magneto-optical spectra of this multilayer system were well explained by theoretical calculations, and the mechanism for the enhancement of magneto-optical effect was shown. Also, the required conditions for application to optical isolators are discussed and some potential solutions are indicated. Since our structure is composed of all semiconductor-based materials, the present results potentially lead to semiconductor based magneto-optical devices integrated with III–V-based optoelectronics.


UV spectrophotometric method has been developed and validated for the determination of Gatifloxacin and Prednisolone Acetate in bulk and eye drop. The λmax of Gatifloxacin and Prednisolone Acetate were found to be 292 nm and 242nm, respectively, in methanol. Beer`s law was obeyed in the conc. range of 0.6-3μg/ml and 2-10μg/ml with correlation coefficient of 0.999 and 0.999 for Gatifloxacin and Prednisolone Acetate, respectively. The result of analysis has been validated as per the ICH guidelines. The developed method is simple, selective and reproducible and can be used for routine analysis of formulations containing Gatifloxacin and Prednisolone Acetate.


A modeling of thin rectangular bar of transverse-type Piezoelectric Transformer (PT) composed by three regions and made from PZT5A (lead zirconate titanate) ceramic material, is reported. The PT (partially metalized on the top and bottom sides) is dedicated to the galvanic isolation. Using the Legendre polynomial approach (PA) based on the polynomial development of the fields, taking into account the lateral dimension (2D study) and the gap (distance between the primary and secondary electrodes), results found are strongly matched through a comparison with those 3D finite element method (FEM). In addition, a good efficiency above 92 % is obtained for this converter. Furthermore, the PA permits to study the influence of the characteristic parameters and allows locating the gap length limit for best PT's performance.


DOI: 10.15414/afz.2015.18.02.44–48 Received 17. December 2014 ǀ Accepted 08. November 2014ǀ Available online 29. June 2015 In this work has been studied the impact of changed vegetation on selected soil chemical characteristics of Stagni-Haplic Luvisol in the Arboretum Mlyňany. Soil samples from A horizons were collected under growths of anthropogenically introduced (cherry laurel and Jeffrey pine) and indigenous (Norway spruce, common yew and oak-hornbeam) tree species. Since the original vegetation in Arboretum was oak-hornbeam forest, the soil under rest of that forest was used as control. Obtained results suggest that anthropogenic change of vegetation highly significantly affected the soil chemizm in A horizons under both, indigenous and introduced tree species. Cherry laurels and Jeffrey pines (their litter, root exudates) had the most significant effect on changes of studied soil chemical properties compared to the soil under original oak-hornbeam forest. The most affected were values of sum of base cations, base saturation, content of available phosphorus and exchangeable aluminum.


This paper discusses research which was stimulated by the controversial question of the educability of entrepreneurial characteristics and the economic value of enterprise training. The research focuses on participants on enterprise training courses within the Irish Republic which aim to help people to set up and run businesses. An attempt was made to develop a technique, that is an adapted Osgood's Sematic Differential Technique, for use in the exploration of participants' perceptions of entrepreneurial characteristics. This technique could represent a useful assessment technique for appraising participants' attitudes to themselves as entrepreneurs and any changes over the duration of a training course in participants' identification with entrepreneurial characteristic. Although, this technique would require self assessments, it could be used to establish the conditions for the development of entrepreneurial characteristics and explore questions of whether entrepreneurial characteristics may be developed. Despite methodological limitations, the reported study lends support to the thesis that many entrepreneurial characteristics may be developed over the duration of enterprise training courses in the view of participants.


Role of Government as public service and target development country become a better service. Therefore, this government have a control system, evaluation, and measurement performance achieved by government. This study aims to analyze and examine to influence characteristics Local Government and finding Audit BPK for financial progress Local Government District/Cities. The hypothesis (1) characteristics Local Government affect performance Local Government District/Cities, (2) findings Audit BPK affects performance Local Government District/Cities.
Samples are 35 in Central Java Province each year. Then, total sample are 105 observation about performance local government of 3 years (2009, 2010, 2011).The population in this study are all of Local Government District/Cities in Central Java Province 2009-2011. Data were analyzed using Multiple linear regression analysis
The results of this study indicate that five variables that describe the charcacteristics of government, wealth of local government and district status has a positive effect significanton the local government financial progress, size, intergovernmental revenue, and capital expenditures had no effect to the performance of local government districts/cities. While audit findings had no significant on performance of local government.


Hydrostatic bearings possess the advantages of strong bearing capacity, good
stability, small friction coefficient, and long life. The performance of liquid hydrostatic bearings directly
affects the accuracy and efficiency of CNC machining equipment. The performance is conducive to the
development of CNC machine tools towards high speed and heavy load, so it is necessary to sort out and
summarize the existing research results.

This study summarizes the current development status of hydrostatic bearings and explains the development
trend of hydrostatic bearings.

According to the recently published journal articles and patents, the recent experimental research
on hydrostatic thrust bearings is summarized. This paper summarizes many factors that affect the
performance of hydrostatic bearings, and discusses the effect of various factors on hydrostatic bearings.
Finally, future research on hydrostatic bearings is also presented.

The study discusses experimental methods, simulation processes, and experimental results.

Dynamic and static pressure effects can be produced by changing the structure of the oil
cavity of the hydrostatic bearing. This effect can make up for the static pressure loss. By improving the
theoretical formula and mathematical model and proposing a new simulation method, the accuracy of the
hydrostatic bearing simulation can be obtained; the future development trends of the hydrostatic bearing
have been proposed in this paper.


Green hydrogen airships optical interconnects flying cars autonomous EVS breeder reactors laser weapons cryptocurrency quantum chips electroceuticals supercomputers satellite phones and more…


This paper puts a way of measurement based on the stereovision, a useful method about the contact zone of Spiral bevel gears. It exposits designing and realizing of the vision measurement system and analyses the problems of image gathering, camera calibration, feature abstracting and result searching, as well as the accuracy of the measurement.


Health Extension Program (HEP) in Ethiopia was introduced to provide a quality package of health services at the community level, including better health care to women and children, especially in the most rural and remote communities. Sub-Saharan Africa accounted for 62 percent of global maternal deaths; Ethiopia's Maternal Mortality Ratio (MMR) estimated 420 maternal deaths per 100,000 live births, with a lifetime risk of maternal death one in 52. Accordingly, this study examines the challenges and opportunities of institutional delivery by health extension workers Bure, Gojjam. The researchers employed a Mixed-Method research approach to investigate the Challenges and opportunities of institutional delivery posed by health extension workers. The quantitative data were analyzed using descriptive statistics, while the qualitative data were analyzed using thematic analysis. The study finding disclosed that the community and women's perception were significant challenges of institutional delivery closely connected with informants' traditional beliefs and newly acquired knowledge, low level of education, and less contact of health extension workers and community. However, health extension workers contribute to community health promotion by conducting home visits surveys and maternal health education sessions to advise different places through the family organization. The research finding revealed that the need for health extension workers and other community stakeholders has to be equipped with communication skills, mobilization skills, and commitment to the work. So, continuous training has to be given on competency and communication skills to update and increase health extension workers' knowledge of health promotion in general and maternity services.


Abstract:Firsthand accounts of what life was like for students attending the prestigious Thomasschule in Leipzig prior to J. S. Bach's appointment as Thomaskantor in 1723 are scarce. The autobiography of Johann Friedrich Fasch (1688–1758) from 1757 contains an informative section on the musical education he received as a teenager in the early eighteenth century. Specifically, Fasch had been a junior musician at the court of Saxony-Weissenfels when the newly appointed Thomaskantor Johann Kuhnau recruited him for Leipzig in 1701. Over fifty years later, and for the benefit of his readership, Fasch weaves an entertaining "From Kapellknabe to Thomaner" character arc into his engaging narrative; it culminates in a humorous anecdote with an unexpected chronological twist. The latter emphasizes the ongoing impact that Kuhnau's rival, Georg Philip Telemann, had on Fasch's overall Kapellmeister career path.


Objectives: The WorldHealth Organization (WHO) classification (2008) is wid ely usedto d iagnose polycythemia vera (PV). However, some patients clinically suspected of PV may not be definitely diagnosed because they do not have a high hemoglobin (Hb) level, one of the main andessential d iagnostic criteria, or because of the lack of or unfilledminor criteria such as bone marrow biopsy, endogenous erythroid colonies, and serum erythropoietin. The British Committee for Standards in Haematology (BCSH) employed hematocrit (Ht), but not Hb, as an indicator in the PV diagnostic guidelines. Furthermore, if the presence of the JAK2 gene mutation is demonstrated, PV can be diagnosed with Ht only by BCSH. Therefore, we evaluated the usefulness of BCSH criteria for diagnosing PV in Japanese patients. Methods: We determinedhematological andclinical differences in 99 patients who met the BCSH criteria (Group A) and69 PV patients who met the WHO criteria (Group B). Results: All patients in Group B also met the BCSH criteria. Thirty patients in Group A (43%) did not fulfill the WHO criteria. No significant differences were observedin white bloodcell andplatelet counts, serum erythropoietin levels, the JAK2V617F allele burd en, or the risk of thrombosis andtransformation into myelofibrosis between Groups A andB. Conclusions: PV cases diagnosedby the BCSH criteria showedthe same clinical picture as those diagnosedby the WHO criteria. In view of actual clinical settings, the diagnostic criteria of BCSH criteria may be useful for the diagnosis of PV in Japanese patients.


Announcing the launch of ASHA's Identify the Signs, a public education campaign broader in reach, scope, and array of ASHA member-oriented tools than anything we have done in the recent past.


A rapid protocol for Evaluation of the Ecological Status of Mediterranean rivers (RBP) has been designed within the GUADALMED project. This protocol provides the necessary methodology to determine the value of three indices: the QBR index (to evaluate riparian quality), the IBMWP index (former BMWP' for the assessment of biological quality of water), and the IHF index (physical habitat). The protocol also includes methods for measuring river discharge and physicochemical variables of water.


Objective:To investigate the utilization ofβ-hydroxy-β-methyl-glutaryl coenzyme A(HMG-CoA)reductase inhibitors in 71 primary medical institutions in Beijing from 2010 to 2012.Methods:Analysis was made on the utilization of HMG-CoA reductase inhibitors in 71 primary medical institutions in Beijing from 2010 to 2012,including drug names,manufacturers,hospital locations and levels.Results:The consumption quantity and consumption sum of various HMG-CoA reductase inhibitors showed a rising trend year by year.Atorvastatin and simvastatin were two predominant lipid-regulating drugs and their consumption sum accounted for about 90%of the total consumption sum.The quantity and consumption sum of HMG-CoA reductase inhibitors in the first-level hospitals were both significantly lower than those of the second-level hospitals,and corresponding data of suburban hospitals were significantly higher than those of urban hospitals.Conclusion:The most frequently used HMG-CoA reductase inhibitors were atorvastatin and simvastatin in primary medical institutions in Beijing.The consumption sum of drugs by foreign enterprises is higher than that of the drugs by domestic enterprises.


We studied the prognosis of 90 resected Stage IV gastric cancer cases, in regard to curability, each factor and subdivided stage by using the cumulative survival rate. For all 90 cases, the 5-year survival rate (5-y.s.r.) was 8.0%. The curability was 37.5% for the curative resection cases (n=18) and 2.3% for the non-curative resection cases (n=72). The prognosis of curative resection cases was significantly better than that of the non-curative resection cases (p<0.01). For prognosis in regard to each factor, resectable S3 (n=19) was better than non-resectable S3 (n=20), N3 (n=30) was better than N4 (n=8), P1 (n=30) was better than P2, 3 (n=20), and H1 (n=7) was better than H2, 3 (n=7). In regard to the number of factors, prognosis of cases with one factor (n=44) was significantly better than that of cases with two or more factors (n=46) (p<0.02). In stage IV-a (resectable S3, N3, P1, H1) (n=46), 1-y.s.r. was 59.0%, 2-y.s.r. was 47.2%, 3-y.s.r. was 40.0% and 5-y.s.r. was 18.2%. For stage IV-b (non-resectable S3, N4, P2, 3, H2, 3) (n=44), 1-y.s.r. was 17.1%, 2-y.s.r. was 0%. Prognosis of IV-a was significantly better than IV-b (p<0.01).


Outline Dear reader, today you have probably been filmed by several electronic cameras. You were in the visual field of a video camera while you stood close to a cash-machine, while you walked through a railway station or an airport, anytime you entered a bank or large public building, during the shopping in the supermarket and also on many public spaces. Electronic eyes became very abundant in our environment in the last few years. But surveillance is just one of many application fields for electronic vision devices. Artificial vision is also used in industrial manufacture, in safety systems in industrial environments, for visual quality control and failure investigation , for visual stock control, for barcode reading, to control automated guided vehicles etc. In these applications, the human workmanship is replaced by an electronic camera paired with sophisticated computer vision software running on the computer to which the camera is attached. The complete system, comprising one or more cameras, computers and sometimes also actuators (i. e. robots), is called a machine vision system. Although machine vision systems are widely and very successfully used, they are limited to perform narrowly defined tasks under highly controlled and repetitive circumstances. No machine vision system comes even close to the capabilities of human vision in terms of image comprehension, tolerance to lighting variations, image degradation, scene variability etc. Machine vision systems do not see in the same way that human beings are able to and the principle differences between machine vision systems and biological vision systems start right at the front end electronic cameras that are not equivalent to human eyes. Almost all machine vision systems rely on standard electronic imagers that produce images, so called frames, in a regular frequency. Frame-based archi-tectures carry hidden costs because they are based on a stroboscopic series of snapshots taken at a constant rate. All pixels are sampled repetitively even if they have nothing novel to say. The pixel bandwidth is limited by the identical global sampling rate, the frame rate. The dynamic range of frame based cameras is typically limited by the finite pixel capacity for integrated photocharge as well as by the identical pixel gain and integration time. In unsupervised environments with natural lighting, the disadvantages of limited dynamic range and bandwidth can become the limiting factor of the whole machine vision system. Biological visual systems have no notion of a frame. The retinal photorece-potrs work …


In traditional power networks, energy theft is a significant problem that causes severe financial losses to utility companies and legitimate users, jeopardizes system stability, and enables other illegal activities. Recently, governments and utility companies propose the Smart Grid as the next generation electric network to improve the current grid's efficiency, reliability, and security. In the Smart Grid, smart meters are deployed at users' premises to facilitate data collection, system control, etc. However, smart meters are vulnerable to cyber attacks, thus enabling easier energy pilfering. In this paper, we model the amount of energy stolen by a smart meter as a measurement bias, and propose an energy theft detection algorithm based on state estimation. In particular, our algorithm employs weighted least squares (WLS) state estimation, and can identify all the energy thieves in the system. We conduct extensive simulations in IEEE 13-bus and 123-bus test systems to validate our algorithm.


Heat-capacity and susceptibility measurements have been performed on the diluted spin dimer compound Ba₃(Mn1-xVx)₂O₈. The parent compound Ba₃Mn₂O₈ is a spin dimer system based on pairs of antiferromagnetically coupled S=1, 3d² Mn⁵⁺ ions such that the zero-field ground state is a product of singlets. Substitution of nonmagnetic S=0, 3d⁰ V⁵⁺ ions leads to an interacting network of unpaired Mn moments, the low-temperature properties of which are explored in the limit of small concentrations 0≤x≤0.05. The zero-field heat capacity of this diluted system reveals a progressive removal of magnetic entropy over an extended range of temperatures, with no evidence for a phase transition. The concentration dependence does not conform to expectations for a spin-glass state. Rather, the data suggest a low-temperature random singlet phase, reflecting the hierarchy of exchange energies found in this system.


We establish coherent triggered-exchange two-dimensional (TE2D) electronic spectroscopy as an expansion of pump-repump-probe transient absorption spectroscopy and uniquely elucidate the role of higher-lying electronic states in ultrafast photochemistry. As an example, this is demonstrated for a molecular switch present in two ring-open conformations. The formation of a new species-the radical cation-is observed and its precursor state is identified via TE2D.


Today's excimer lasers are well-established UV laser sources for a wide variety of micromachining applications. The excimer's high pulse energy and average power at short UV wavelengths make them ideal for ablation of various materials, e. g., polyimide, PMMA, copper, and diamond. Excimer micromachining technology, driven by the ever-shrinking feature sizes of micro-mechanical and micro-electronic devices, is used for making semiconductor packaging microvias, ink jet nozzle arrays, and medical devices. High-power excimer laser systems are capable of processing large areas with resolution down to several microns without using wet chemical processes. For instance, drilling precise tapered holes and reel-to-reel manufacturing of disposable sensors have proven to be very cost-effective manufacturing techniques for volume production. Specifically, the new industrial excimer laser-the LAMBDA SX 315C-easily meets the high demands of cost-effective production. The stabilized output power of 315 watts at 300 Hz (308 nm) and its outstanding long-term stability make this laser ideal for high-duty-cycle, high-throughput micromachining. In this paper, high-power excimer laser technology, products, applications, and beam delivery systems will be discussed.


Although to reform re-education through labor system has become a consensus in China,there are various opinions about specific paths of the reform.Through empirical investigation,we can realize the basic attitude of theory and practice circle,seek consensus on orientations and plans of the reform.This may fundamentally resolve difficulties in the reform of re-education through labor system.Results of empirical investigations indicate that some reforming plans are highly recognized,for instance,regulating the application range of re-education through labor by legislation,establishing an impartial judicial procedure and reducing the severity of re-education through labor.But respondents show little tendency towards other reform plans,such as replacing the re-education through labor system with misdemeanor charges,security measures or educational treatment.After comparative studies on jurisprudence and comprehensive analysis of different reform plans,we can discover that two plans are available to reform re-education through labor system- establish Education and Correction Law for Illegal Act,or divide the objects of re-education through labor into administrative and criminal catalogues.Comparatively speaking,the former plan is more feasible.The reform of reeducation through labor system should adhere to the international conventions on human rights,following the fundamental orientation of human rights protection;the reform of re-education through labor system should be of comprehensiveness,considering both substantive and procedural aspect equally;the specific reforming measures should be based on empirical study,in accordance with the general development trend of relevant legal system,in correspondence with universal rules and in coordination with domestic legal system.


treatment of the subject, demands which an introductory text may be excused from meeting. The text has definite virtues. As an introductory text it is clear and well presented. Armstrong includes excellent sections in the chapters on carbohydrate and lipid metabolism which make the biochemical pathways have medical relevance. There are excellent, up-to-date chapters on DNA sequencing and hormones (including a section on prostaglandins) and a well-presented and useful chapter on human nutrition. Along with another good chapter on the B vitamins, the human nutrition chapter clearly and thoroughly discusses the biochemical importance of the vitamins. Armstrong's Biochemistry lacks the depth that a rigorous biochemistry course requires in its textbook. However, as a text for an introductory college biochemistry course or for an advanced high school course dealing with biochemistry, Armstrong's volume is a good choice with the added benefit of some excellent chapters in important areas of biochemistry.


The purpose of this research is to find out how the service for making electronic ID card during the Covid-19 pandemic at the Department of Population and Civil Registration of Baubau City, as well as what are the inhibiting and supporting factors in providing services to the community. This research uses a descriptive qualitative approach through literature studies. The results show that the Department of Population and Civil Registration of Baubau City has implemented public services according to service standards in making electronic ID card, where services are carried out online using the WhatsApp (WA) application via an Android phone, the public is also free of charge in the manufacturing process, providing facilities and adequate infrastructure in accordance with the Covid-19 health protocol, and placing competent officer to facilitate service delivery. The results of this study also reveal the factors that affect the service of making electronic ID cards at the Department of Population and Civil Registration of Baubau City, during the Covid-19 pandemic, namely: supporting factor where the tools available in providing services are adequate and the human resources competent in their field. Even though there are several technical obstacles, especially from the internet network, not all people have an Android phone and understand the mechanism of online service.


This paper proposes a new video coding algorithm using the multi-dimensional transform. The multi-dimensional transform achieves both the accuracy of temporal prediction as well as effective use of spatial redundancy. Moreover, two additional methods for multi-dimensional transform are proposed, which are cube forming and modified transform coefficient thresholding. These combined schemes lead to a bitrate saving on FRExt profile, compared to an H.264/AVC standard codec, which reach up to 2.88%.


Selecting the correct feature set is an essential basis for video sequence analysis that leads to applications such as tracking and recognition of vehicles. This paper selects diverse multiple features and tests their accuracy for tracking a static vehicle. The static vehicle images are captured with airborne infrared and color video cameras. The camera collects 30 frames per second of compressed video in Motion JPEG format. The diverse features are selected from representative histogram-based, invariant-based, spatial-temporal-based and the center-symmetric autocorrelation-based family of features. A small dataset of airborne video sequences that include static vehicles with variations in quality, orientation, resolution, foreground lighting and background lighting are used to test feature selection and static tracking. The track of the vehicles is hand selected frame-to-frame to create a truth track. The result of each feature to maintain track is tested and scored based on distance from the truth track. Once a significant break from track occurs, the truth data is used to reacquire track. One goodness score is based on how often a feature breaks track. This analysis shows promise for identifying appropriate features for improved tracking results. The suggested algorithm is demonstrated on only a few video sequences with limited variations in operating conditions but demonstrates improvement possibilities for near real-time application.


Neoadjuvant chemoradiotherapy (nCRT) has become the standard treatment for patients with locally advanced squamous cell esophageal cancer (LA-ESCC). Patients with the complete pathologic response (pCR) have significantly improved long-term survival. All efforts should be to improve the accuracy of predicting pCR. In this study, we investigate the use of radiomics based on machine learning to identify the pathologic complete response of patients with esophageal squamous cell carcinoma (ESCC) based on Computed Tomography (CT).

 The study included 155 patients with pathologically confirmed LA-ESCC. All 155 patients underwent simulation CT before nCRT, Quantitative radiomics features were extracted from CT images of each patient. To explore the relationship between radiomics features and the pCR, we used five-fold cross validation to classify the training and the testing cohorts. The Least Absolute Shrinkage and Selectionator operator (Lasso) were used to select features useful for the grading of pCR in the training cohort. Different models were measured in the training cohort using accuracy, sensitivity, specificity, and area under the curve of the receiver operating characteristic curve (AUC).

 There were 155 patients. The pretreatment clinical stage was II in 16 patients (10.3%), III in 132 (85.2%), and IV in 7 (4.5%). Pathologic response was complete in 69 patients (44.5%), near-partial complete in 86 (55.5%). A total of 2193 radiomics features were extracted in the training set. After the use of statistical dimensionality reduction, five radiomics features were selected by Lasso to build radiomics signature. Prediction models for pCR were developed, and the model was able to predict pCR well in the training set(AUC = 0.902). In the testing cohorts, the model had a good performance in predicting pCR (AUC = 0.78).

 This study showed that CT-based radiomics features could be used as biomarkers to predict the complete pathological response of esophageal cancer underwent Neoadjuvant chemoradiotherapy.


In response to sustained increase in contractile activity, mammalian skeletal muscle undergoes adaptation with enhanced mitochondrial biogenesis and fiber type switching. The peroxisome proliferato...


Background: Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous disorder characterized by a progressive weakening and spasticity of the lower limbs. HSP is classified according to the presence or absence of accompanying neurologic problems and by the mode of inheritance. Currently, 17 loci have been linked to the various forms of HSP. Objective: To determine the chromosomal location of a gene causing pure autosomal recessive spastic paraplegia. Methods: Genotyping using fluorescently labeled microsatellite markers was performed on three affected individuals and three unaffected individuals from a family displaying pure autosomal recessive HSP (ARHSP) and sensorineural deafness. All family members were then included in the analysis to narrow the genetic interval. Candidate genes were screened for the presence of mutations by heteroduplex analysis. Results: The paraplegic trait linked to a 1.8-Mb region of chromosome 13q14 flanked by the FLJ11712 gene and the microsatellite marker D13S270. The deafness did not link to this region and did not cosegregate with the paraplegic trait. Conclusion: The HSP that this family had represents a novel genetic form of pure ARHSP as no other form of HSP (autosomal dominant or recessive) has been linked to chromosome 13.


By choosing the following variables: labor costs, market size, economic openness, basic labor quality, regional labor supply size, infrastructure development, capital output ratio and the total cumulative FDI stocks, we established a panel data model and estimated the effects of the determinants of foreign direct investment (FDI) in 9 areas of Fujian Province from 1999 to 2007. We found that the total regional foreign trade volume, road density and cumulative FDI stocks had a positive effect, but the average wage levels and the number of primary school students had a negative effect on FDI.


The intracellular cargo delivery performed by kinesin motor proteins can be biomimetically employed to engineer tailor-made artificial nanotransport systems. Kinesin (expressed on an Escherichia coli system) and microtubules (obtained from the polymerization of tubulin proteins) were prepared and characterized. We report recent results and explore the aim of the construction of biomotor-based NanoElectroMechanical Systems (NEMS) and their potential applications, e.g. as drug delivery systems.


As the key regulator in maintaining blood sugar, insulin is secreted by beta cells residing in pancreatic islets. However, most functional beta cells are disappeared in type I diabetes, and the total beta cell population is seriously reduced in type II diabetes. Over the last decade, insights into beta cell development, combined with the deeper research of related donor stem cells including ESCs, iPSCs and pancreatic progenitors, have led us to generate functional beta cells. Besides, several alternative approaches have also converted other cell types into insulin positive beta-like cells via lineage reprogramming factors (Pdx1, Nkx6-1, Pax4 and Ngn3). Nowadays, people realized that advances in investigating of beta cell biology at the genomic and post-transcription levels are more useful in deeply understanding the cells source, behavior and function. For research in drug screening or diabetes transplantation therapy, herein, we reviewed the recent information about development, replication of beta cells, and production of insulin-positive cells via lineage reprogramming or small molecule treatment.


Fluoride varnish is commonly used as topical fluoride therapy to prevent dental caries. Dental caries is a dissolution of tooth surface caused by the metabolic activity of Streptococcus mutans in the presence of carbohydrates. Fluoride varnishes containing antibacterial agents significantly affect the inhibition zone of Streptococcus mutans. Prior studies also note the inhibitory effect of wuluh starfruit (Averrhoa bilimbi L.) leaves extracts and fast release fluoride varnish containing red betel (Piper crocatum) leaves extracts on Streptococcus mutans. The purpose of this study was to evaluate the antibacterial effect of adding wuluh starfruit leaves extracts, and red betel leaves extracts to a formulation of fluoride varnish on the growth inhibition of Streptococcus mutans, the fluoride ion release, and the pH obtained from the fluoride varnish. The concentration of antibacterial extracts used was 0.1 g/mL each and MI Varnish served as control. The growth inhibition zone of Streptococcus mutans was measured using disk-diffusion agar method with 3 repetitions. The data produced were analyzed using the Kruskal-Wallis and Mann-Whitney U-tests. Fluoride varnishes containing antibacterial agents used in this study resulted in greater inhibition zone of Streptococcus mutans than control (P < 0.05). The addition of red betel leaves extracts resulted in greater mean diameter of inhibition zone (14.22 mm) than that of wuluh starfruit leaves extracts (13.75 mm), but there was no significant difference (P > 0.05). The fluoride ion release of fluoride varnish containing red betel leaves extracts and wuluh starfruit leaves extracts after 360 minutes is 269.08 mg/L and 229.32 mg/L, respectively. The pH of both fluoride varnishes is above the critical pH of hydroxyapatite. Thus, wuluh starfruit leaves extracts, and red betel leaves extracts have the potential to be used as one of the ingredients in the formulation of fluoride varnish to achieve better growth inhibition of Streptococcus mutans.


The purpose of this report is to provide a useful resource for communities that wish to learn how others have successfully used bus rapid transit (BRT) as a tool for enhancing the public realm. Information for this effort was gathered through a literature review, in-depth profiles of three BRT systems, and a detailed questionnaire that was administered to transit agencies in the United States, Canada, and Australia. While the literature review provides historical background on the relationship between transit projects and the public realm, the questionnaire focuses specifically on the interaction between BRT and public space. The system profiles provide a detailed account of the Los Angeles Orange Line, Cleveland's HealthLine, and the EmX in Eugene, Oregon, along with recommendations and lessons learned. It should be noted that this report does not attempt to offer detailed instructions of the type that would be found in design manuals or other highly technical literature. Rather, the focus is on sharing the experiences of agencies that have been successful in designing and building community value into BRT projects.


FPGA-based implementation of tree-based classifiers has been a very promising approach due to the ability of FPGA to execute tasks in parallel, which speeds up the processing tasks and saves power. The challenge with FPGA implementation is the need to build all classifier components in hardware, structure format, which is time-consuming and does not follow the best practices in creating modular design architecture. This paper addresses this issue by proposing a hardware-software codesign implementation of a tree-based classifier that uses ID3 algorithm for classification tasks. We used the Xilinx microblaze processor inside the FPGA to execute ID3 algorithm functions, while using hardware modules for pre-processing and feature engineering tasks.


The invention provides a sending and receiving method and device for personal messages. More specifically, the method for sending the personal messages comprises the steps that the personal messages are embedded in an extension structure which needs a shared file or in an original reserved position structure, and the shared file is sent; the method for receiving the personal messages comprises the steps that the shared file is received, and the personal messages are extracted from the extension structure or the original reserved position structure of the received file. According to the sending and receiving method and device for the personal messages, the personal messages are embedded with the shared file as a carrier; while the file is shared, interaction among the personal messages is realized, the interaction speed of the personal messages is increased tremendously, and user experience is improved greatly.


Nowadays, Wi-Fi is a very popular Technology. Faster data transfer and Security both are very important for Wi-Fi. At present, Advanced Encryption Standard (AES) is used for Wi-Fi that is more secured than other encryption algorithms but it is not so fast because of it's complex functions. On the other hand, Blowfish is a very faster encryption algorithm but it cannot apply on Wi-Fi because of it's security problems. In this paper, a hybrid algorithm of Blowfish and Rivest Cipher 6 (RC6) is proposed that solves the security problems of Blowfish and also maintains the fastness of Blowfish and makes it able to use it in place of AES. It uses two innovative criteria. One is ingenious confusion process using two random numbers "a" and "w" that removes reflectively weak key attack and Known plaintext attack of Blowfish. The other is usage of one S-Box by overlapping process that eliminates the collision key attack of Blowfish. Sub key generation process of this algorithm also removes the Brute Force attack of AES. This paper tries to give an efficient algorithm that enhances the performance of Blowfish algorithm by adding a function of RC6 with it. The adding process is trickily handed here that makes the proposed algorithm as fast as Blowfish and also secured like existing AES. The proposed algorithm takes less encryption -decryption time like Blowfish and also secured like AES. Throughput, Average time for different data lengths and attack removal process are used to measure the efficiency of this proposed algorithm.


The purpose of signal restoration is to acquire a clean signal from the degraded signal which contains blur and noise. In this paper, a modified Tikhonov regularization method based on the standard Tikhonov regularization matrix is proposed, and the corresponding preconditioner is designed to accelerate the convergence of the proposed algorithm. The proposed method shows the best performance than several competitive methods. In addition, the convergence speed is improved significantly.


This paper presents a new local feature called Fuzzy Shannon entropybased features for face recognition. These features are computationally simple and capture the variation in the face image. The new Fuzzy membership functions are defined which are not like standard Gaussian or trapezoidal membership functions, but they are computed with normalized Image intensity values. This paper gives the flexibility to design of new membership functions to cater the need of the problem. The Information set is the combination of fuzzy membership and Information source (attributes). By applying this concept, we have extracted features from ORL and Faces94 databases with Support Vector Machine and K Nearest Neighbour classifier the results obtained with the proposed method are better than other published contemporary techniques.


With the changes of law and order and the complexity of criminal activities,undercover investigation is being widely used in China for the investigation of smuggling,drug dealing and other cases alike.However,there are many problems in practice because the legal system of undercover investigation in China is still at the beginning of establishment.Therefore,it is urgent and necessary to take an action for the legislative building and regulating of undercover investigation..


The stationary Stokes and Navier-Stokes equations of a viscous incompressible fluid with additional flux conditions are considered in domains Q with m ~ 1 outlets to infinity, which have in some coordinate systems the following form The complete asymptotic decomposition is constructed for the solution of the Stokes problem in the case when the right-hand side has either a compact support or a special series representation. For the solution of the nonlinear Navier-Stokes problem the asymptotic decomposition is constructed in the case of zero right-hand side. The obtained asymptotic decompositions are justified in weighted H61der spaces.


This paper presents a method to determine travel time, attenuation and frequency characteristics of partial discharge signals travelling along a power cable. The method is based on the Advanced Transient Program. Laboratory tests performed on 13 kV EPR insulated cable are used to validate simulation results. The model developed here will be used in forthcoming papers to assess partial discharge detection sensitivity as a function of cable length and detector bandwidth. Here, some preliminary results are presented.


ANALYSIS ON THE FACTORS THAT AFFECT AMOUNT OF INDOSAT\'S CUSTOMERS PAYMENT - wireless telecommunication industry, customers amount of payment, service usage, customers loyalty, effective product knowledge sharing


[Objective] This study is aimed to isolate and characterize feather-degrading bacteria from soil,and to determine the optimal temperature and initial pH for growth and further to observe the dynamic of enzyme activity.[Methods] Serial dilution on agar plate and selective medium culture techniques were used for screening bacteria.Strain identification was based on phylogenetic analysis of 16S rRNA gene sequence and Biolog analysis.Optimal growth conditions were measured by automated microbiology growth curve analyzer.The proteolytic activity assay was carried out to observe the dynamic of enzyme activity.[Results] A feather-degrading bacterial strain,designated as GIMN1.015,was isolated and screened from the soil mixed with feathers.The strain was preliminarily identified as a strain of the genus Sporosarcina.The optimal pH and temperature for growth were 9.0 and 30 °C,respectively.The peak value of proteolytic activity appeared at 96 h of incubation time.[Conclusion] Strain GIMN1.015 has the potential for the application of feather keratin sources.This is the first report on the feather degrading by Sporosarcina.


anti-anxiety agent.1 Mikashima et al. examined the antagonistic effect of etizolam on pletelet-activating factor (PAF). They demonstrated that the compound is a specific PAF receptor antagonist by examining its effect on platelet aggregation and on PAF receptor binding in vitro.2 The X-ray analysis of etizolam has been undertaken in order to understand its interesting biological activities. It is extremely difficult to obtain crystals of etizolam suitable for single-crystal X-ray diffraction. Crystals always appear as very small colorless crystals and diffract poorly. The best crystal with the dimensions of 0.2×0.1×0.1 mm was obtained from an ethyl acetate solution at 293(5)K and was used for the diffraction experiments. The crystal and experimental data are given in Table 1. The structure was solved by direct methods and refined by full-matrix least-squares methods with anisotropic temperature factors for non-H atoms. All H atoms except those of ethyl and methyl groups were found from difference Fourier maps and were refined isotropically. Although H-atoms of ethyl and methyl groups were placed at calculated positions and included in the structure factor calculations, they were not refined. Atomic parameters for non-hydrogen 407 ANALYTICAL SCIENCES APRIL 1999, VOL. 15


Battery-less devices offer potential solutions for maintaining sustainable IoT networks. However, limited energy harvesting capacity can lead to power failures, limiting the system's quality of service (QoS). To improve timely task progress, we present ETIME, a scheduling framework that enables energy-efficient communication for intermittent-powered IoT devices. To maximize energy efficiency while meeting the timely requirements of intermittent systems, we first model the relationship between insufficient harvesting energy and task behavior time. We then propose a method for predicting response times for battery-less devices. Considering both delays from multiple task interference and insufficient system energy, we introduce a dynamic wake-up strategy to improve timely task progress. Additionally, to minimize power consumption from connection components, we propose a dynamic connection interval adjustment to provide energy-efficient communication. The proposed algorithms are implemented in a lightweight operating system on real devices. Experimental results show that our approach can significantly improve progress for timely applications while maintaining task progress.


7475 Al alloy reinforced with Al2O3 particulates of different sizes (25 μm angular or 40 μm microsphere) and volume fractions were successfully produced using vortex method followed by extrusion. SEM and energy dispersive X-ray analysis (EDXA) taken from the extracted Al2O3 particulate revealed that the particulate reacted with the molten 7475 Al during melting and casting to form a layer of MgAl2O3 spinel at the interface. Microstructural parameters, such as volume fraction, size and shape of the particulates, were correlated with the ambient and elevated (200 o C) temperature tensile properties as well as failure mechanisms. At both temperatures, the composite had higher yield strength than the unreinforced alloy, increasing with increasing the particulate volume fraction. The elongation was lower in the composite, decreasing with increasing level of reinforcement and increasing with increasing temperature. The Al2O3 particulate size had a marginal effect (within the particulate size range studied here) on the tensile properties. Although these composites exhibited limited ductility on a macroscopic scale, fractography revealed that fractures occurred by a locally ductile mechanism. The microstructural damage in the composites also varied with the temperature: particulate fracture dominated at ambient temperature and interfacial debonding and particulate fracture were the main damage features at elevated


The current research investigated a phenomenon that has received little attention so far: the labelling of students who are characterised by a strong academic orientation. We analysed whether personality predicts being labelled a 'Streber' (literally a person who strives for success; German origin, similar to the English word 'nerd') and labelling others as Strebers. Besides individual characteristics, we examined the impact of the classroom context. In Study 1 (N = 317), eighth–grade students nominated classmates who were considered to be Strebers and provided self–ratings on how often they had labelled others as Strebers. In Study 2 (N = 358), using a round robin design, we had students rate each of their classmates on the extent to which the students perceived their classmates to be Strebers. Results showed that being labelled was associated with introversion and conscientiousness. Labelling others was related to extraversion, low conscientiousness and low agreeableness. Furthermore, the labelling and the expected relation between individual characteristics and labelling were stronger in high–achieving than in low–achieving classes. Results are discussed with respect to personality traits as potential risk factors in peer stigmatisation and the impact of the classroom context. Copyright © 2012 European Association of Personality Psychology


Urban Planning is one of the kernel courses and plays a crucial role in department of Urban Planning.The present teaching,however,has some shortcomings,which are summarized and some suggestions on teaching reform and curriculum construction are put forward in the paper.


West Circassian displays prominent polysynthetic morphology both in the verbal and nominal domains and both syntactic categories are subject to the same morphological ordering constraints. I argue that despite these similarities, nominal and verbal wordforms in West Circassian are in fact constructed via two distinct word formation processes: while the verbal root and any accompanying functional morphology are pronounced as a single phonological word by virtue of forming a single complex syntactic head via head movement, the nominal head and its modifiers are pronounced as a single word due to rules of syntax-to-prosody mapping. Such a division of labor provides an account for why only nouns, and not verbs, exhibit productive noun incorporation in the language: West Circassian noun incorporation is prosodic, rather than syntactic. The evidence for the existence of these two avenues of word formation comes from a systematic violation of morpheme ordering observed in verbal nominalizations. In terms of broader theoretical impact, the proposed analysis provides insight into what factors shape a polysynthetic language: while it is tempting to reduce polysynthetic morphology to either simple head movement or just a consequence of mapping complex syntactic structure to a single phonological word without any head movement, the West Circassian data show that neither of these mechanisms can be dispensed of.


The article shows the relationship between the development of information technologies, the characteristics of the information society and digital art. The broad possibilities of the digital world related to recording, storing and processing data (cyber text, big data, smart services) and the creation of virtual worlds are pointed out. The influence of the development of information technologies on the character of the works of art (their variability and availability) is also considered. On the basis of representative examples, three areas of border-crossing in the manner of presenting and experiencing a digital art work are distinguished: entering the public space, virtual world and the recipient's private area. The possibilities of integrating the digital message within the architectural structure in the public space (media architecture using display technology and temporary projections) is indicated. The possibilities of digital art in the virtual world is also taken into consideration (generative art, Net Art, virtual museums). Moreover, the issue of digital art in the context of crossing the border of human privacy by means of information technology (monitoring, surveillance) is considered, stressing also the social aspect of interactive art. The article shows the almost unlimited possibilities in the field of digital art, which are determined only by the imagination of the artist.


In the conditions of innovative development of Polytechnic education and society in general in an educational paradigm there are basic changes. Today, the main units of updating of content of education are competence, the characteristic of their types and structure. Understanding students of existence of cross-disciplinary communications the importance of the studied disciplines in their interrelation and interaction is determined by cross-disciplinary competences. In modern conditions, the role of geometric-graphic preparation is greatly expanded. The advantage is given to those professionals whose thinking is able to synthesize imaginative and rational. The development of the ability to such a synthesis is greatly facilitated by mastering the methods of geometric-graphic modeling of objects and processes. Let us emphasize that models based on geometric and graphical methods (with the ability to visualize the model) are often more effective in practice than purely analytical models. Therefore, the development of the theory of geometric modeling (with computer visualization) should not be considered in the narrow sense of geometric-graphic preparation, but as a self-valuable component of geometric-graphic education. The author substantiates the essence of cross-disciplinary integration, presents the mechanisms of integration of disciplines at the Polytechnic University, pedagogical conditions, methods of teaching the theory of geometric-graphic modeling, as well as the results of practical implementation of theoretical provisions.