The purpose of the article is to identify groups of costs that are inherent in life-cycle stages of venture companies and which directly are the objects of accounting. The author distinguishes stages of the life cycle of the venture company with an indication of the degree of risk and the need for venture capital, which determine the accounting tasks required to reflect it. The model of lifecycle accounting of venture company is grounded. The conventional range of expected return on the invested capital is described, depending on the stage of the life cycle of the venture company. It is demonstrated the dependence of the risk, the payback period and the amount of venture financing, depending on the stage of the life cycle of the venture company. Defined the groups of costs that are inherent to life-cycle stages of the venture company. The proposed classification of expenses will help managers in making rational decisions, thanks to: 1) the possibility of measuring the impact of the expenditures, depending on the stage of the life cycle of the venture company, to the level of costs and the profitability of production; 2) the allocation of that part of the cost, which the managers may effect on.


Rheumatoid arthritis frequently results in synovitis and deformity of the ankle and foot. Rheumatoid vasculitis presents with skin ulceration, digital ischemia, nodules, and mononeuritis multiplex. The relationship of disease duration and deformity is discussed in 50 patients with rheumatoid arthritis.


The utility model relates to mechanical components, in particular to an integrated manipulator connecting seat. The integrated manipulator connecting seat comprises two connecting seat units which are of an integrated structure with two lateral sides cast in one; a mounting seat unit is provided with a mounting groove, mounting grooves of the two connecting seat units are vertically arranged, or the mounting seat unit is provided with a mounting groove, and the mounting grooves of the two connecting seat units are arranged by an angle of 135 degrees. The integrated manipulator connecting seat has the advantages of easiness in mounting, low cost and high enduring strength.


Background: After comparing data of NFHS-3 and 4, prevalence of overweight and obesity in women of an urban population almost doubled in 10 yr. So, the causes of increasing prevalence need to be studied as public health concern. Objective of the study is to determine prevalence of overweight and obesity among reproductive age group (15-49 years) of women in an urban slum of Mumbai.Methods: Total 220 women were selected among 11 sectors from A to K by simple random method and data collected by using validated questionnaire. WHO's classification was used to classify as overweight and obese.Results: Out of 220 women participated in study, 14 (6.36%) were obese, 75 (34.09%) were overweight according to BMI and 17 (7.7%) were found to be obese according to waist to hip ratio. From the present study it was seen that age group of the women, socio economic class, education, history of hypothyroidism, family history of obesity, types of work women do, hours of television watching, calorie and fat intake, had a significant relationship with BMI, whereas physical exercise they used to do and tendency to sleep in the afternoon and hours of sleep in the night had non-significant relationship with BMI.Conclusions: Obesity and overweight is found to be a growing public health problem and can be preventable. Interventional measures include developing healthy eating habits, regular moderate physical exercise, sleeping habits, health camps for screening of overweight and obesity.


Through an electrostatic discharge (ESD) damage case study of giant magnetoresistive (GMR) head in shunting process of head gimbal assemblies (HGA), this paper unveils that GMR heads would be damaged by a combination of field-induced voltage on HGA and surrounding trigger event. This investigation further demonstrates that the ESD protection technique, which derives from metal-to-metal contact to GMR terminals and thus focuses on eliminating metal-to-metal contact to GMR terminals, is not sufficient to prevent ESD. The electromagnetic interference caused by nearby trigger event needs to be noted also in the ESD control.


Objective. To analyze the teach-learning process of high school students, in the scope of Educational Biology. To plan and to develop a methodology with lesson strategies that facilitate the learning. To analyze, in the students vision, the positive and negative points in the process. Method. A research was developed -- of which had participated students of the first semester of the Pedagogy of a high school private institution in Sao Paulo city -- of the type action-research, with increased qualitative character of quantitative instruments; as a way of data collect, had been used questionnaires and field diary; the results had been converted in charts; after that, the data collected by the questionnaires had been analyzed according to the technique of the collective subject analysis. Results. The results had supplied important information to high school teachers reflection about teach-learning process, showing that the used strategies allowed student envolvement and participation, proximity with personal and professional reality, bigger interaction in the interpersonal relations and critical reflection. Conclusions. The theoretical referencial about adult learning, the active methodologies and the interpersonal relationship between professor and pupils, with the analysis of the students vision about the positive and negative points in the teach-learning process, had provided subsidies to believe a methodology and specific didactic strategies for adults and that must contemplate the teachers motivation and the pedagogical communication, including elements like creativity, up to date technician content and formative content to the future profession, experiences exchange, that allow an affective relationship teacher-student, with interaction and dialogue.


Although very few prospective clinical trials are available assessing the benefits of drugs in isolated REM sleep behavior disorder (iRBD), clonazepam and melatonin are considered as the first-line treatment options. However, while evidence supporting the efficacy of these two compounds on the clinical behavioral outcomes seems to be clear, it is not clear if they are able to significantly modify the main polysomnographic (PSG) feature of iRBD, i.e. REM sleep without atonia (RSWA). For this reason, we carried-out an observational cross-sectional retrospective PSG study of the effects of clonazepam and melatonin on RSWA.

 A total of 83 iRBD patients (70 males and 13 females, age range 50.9-83.2 years) were enrolled in this study: 43 drug-free, 21 patients taking at bedtime chronically (>6 months) clonazepam (0.5-2 mg), seven patients taking melatonin extended-release alone (2-3 mg), and 12 taking a combination of clonazepam and melatonin extended-release (same doses as above). PSG studies were assessed for all subjects, including the measurement of the automatic REM sleep atonia index (RAI) and periodic leg movements during sleep, as well as a series of demographic and clinical variables, such as age, age at onset, disease duration, clinical global impression scale (severity and improvement), mini-mental state evaluation, and RBD severity scale.

 None of the outcomes considered in this study showed significant differences between the groups considered. All showed low average values of RAI, as expected, and there were no differences between patients taking clonazepam, melatonin, or a combination of them (drug-free 0.778±0.184, clonazepam 0.797±0.183, clonazepam+melatonin 0.692±0.224, melatonin 0.673±0.228; ANOVA F = 1.329, p = 0.271), despite the clinical global impression scale-improvement was reported to be "much improved" or "minimally improved" in all treated patients.

 This study confirms our previous findings in smaller patient series taking only clonazepam and suggest that both clonazepam and melatonin might be beneficial on some clinical manifestations of iRBD but are unable to modify its underlying neurophysiology. This might also indicate that these agents do not seem to interfere with the core mechanisms of this disease and other disease modifying drugs need to be discovered for iRBD.


The mismatch between illumination and traffic safety brightness in tunnels leads to much-wasted lighting energy and safety problems. Effective control of tunnel lighting can be achieved by lighting on demand and reducing lighting energy consumption. This paper uses the curve fitting and linear interpolation methods to optimize the luminance reduction factor K proposed in the Highway Tunnel Lighting Rules. It constructs a multi-zone division of traffic speed, traffic flow, and brightness outside the tunnel to obtain the K value under actual road conditions and to establish a fuzzy controller for dimming control. The simulation demonstrates that the proposed strategy can save about 37.38% of tunnel lighting compared to the graded lighting control strategy.


Rules are the orientation for the development of the event.The new rules in 2013 for grading in boxing match have made great changes,which makes effects on the development of boxing.This paper conducted a systematic analysis on core characteristics of new rules,the tactics and the strategies of lightweight boxers adopted before and after rules and Olympic preparation strategy.The results show that the new rules make boxing to return to its essence as a competitive sport.The core characteristics of the changes lie in the strengthening of rivalry and intensifying of the competition.There're remarkable increases in the number of punches,against the times,and combination of punches;there're also decreases in the number of single punches,defense tactics,and the cases of defense without countering back.For lightweight boxers who want to have good performances in the match,they must reinforce their attack and improve the frequency of the punches;besides,they should also increase their speed of attacking,and improve their rival ability.Moreover,they should try to control their opponent and the match,improve their physical ability to satisfy the need for intensive rivalry.


We present photometric observations of the field around the optical counterparts of high-mass X-ray binaries. Our aim is to study the long-term photometric variability in correlation with their X-ray activity and derive a set of secondary standard stars that can be used for time series analysis. We find that the donors in Be / X-ray binaries exhibit larger amplitude changes in the magnitudes and colours than those hosting a supergiant companion. The amplitude of variability increases with wavelength in Be / X-ray binaries and remains fairly constant in supergiant systems. When time scales of years are considered, a good correlation between the X-ray and optical variability is observed. The X-rays cease when optical brightness decreases. These results reflect the fact that the circumstellar disk in Be / X-ray binaries is the main source of both optical and X-ray variability. We also derive the colour excess, E ( B − V ), selecting data at times when the contribution of the circumstellar disk was supposed to be at minimum, and we revisit the distance estimates.


This study is based on 93 Spinturnicidae specimens collected on 312 bat specimens obtained from various parts of Turkey. As a result of the study, six mite species were identified: Eyndhovenia euryalis (Canestrini, 1884), Spinturnix acuminatus (Koch, 1836), S. myoti (Kolenati, 1856), S. psi (Kolenati, 1856), S. plecotinus (Koch, 1839), and S. punctata (Sundevall, 1833). Of these species, S. plecotinus and S. punctata are new records for the Turkish fauna.


China's trade deficit in international transportation services has been viewed as a to-ken of poor competitiveness.After analyzing the status quo of China's trade in transportation ser-vices,and examining the index of TSC and RCA of China's transportation services industry,this paper,on the basis of the quantitative analysis,ascribe China's trade deficit in transportation services to the supply shortage rather than the competitiveness of China's transportation industry.


School is the place of spreading knowledge and cultivating talented persons.The teacher team must be built to accelerate the evolvement of higher education.On the basis of the analysis of university teacher team construction in China,the paper points out the necessity and pattern of its building,sum up the items that deserve notice.


On the basis of service conditions and failure forms of screw-contact,some technologies such as the materials optimization,moulding,welding as well as strengthening and toughening treatment were studied,and the high performance screw-contact used by high voltage SF_6 circuit-breaker were developed.The results show that the tensile strength of beryllium-bronze QBe1.9 after aging treatment at 345 ℃ for 1.5~2.0 h is 930 MPa and it can meet the requirements of the screw-contact.Welding strength of the screw-contact is 492 MPa,which is as same as that of the matrix(520 MPa).Its geometry precision after being shaped by break-bending can meet the requirements of product design.The average service life of the screw-contact is more than 10 000 times and has reached the same level that made abroad,while the former is much cheaper than the latter.


To develop low-cost and high throughput method for melamine(MA) determination in milk and dairy product,a sensitive high performance thin layer chromatographic(HPTLC) method was initially established.MA concentrated during developing on plate.On a high performance silica gel G plate(domestic product),with tetrahydrofuran,water and acetic acid as the basic developing agent,Chlorine and iodine/starch reagent applied as staining reagent,the detection limit reached 5.0~2.5 mg/L,even reached 1.0~0.5 mg/L level in optimized experiment.Obviously HPTLC can be use to build an inexpensive,easy operating and high efficient MA residues detection.


Researches in history of modern China in the past fifty years have made rapid progress in America. In this thesis, the development of perspective of history of modern China in America is presented and examined, which is based on Discovering History in China. And the author also makes some suggestions on the trend of research in history of education in China in the new century.


The Forgotten Memoir of John Knox, edited by Dennis J. Hutchinson and David J. Garrow in 2002, revealed how badly Justice James C. McReynolds treated his clerk in the 1936 Term. Was Knox's negative clerkship experience typical? An examination of the numerous letters written home by Milton S. Musser, McReynolds' clerk from May 1938 to October 1940, provides a valuable comparison.Musser's letters are also a window into the hiring process, duties and salary concerns of Supreme Court clerks in his era.


Fluorine negative ions (F-) produced by a column-type magnetized plasma with CF4 gas diffuse radially and accumulate around the plasma column. To explain the features of this accumulation, the radial profiles of the negative-ion density n- as functions of discharge parameters are measured using a hot-wire-type Langmuir probe. The modified Bohm theory is applied to evaluate n- as n-/ne>2 and the negative ions are well confined between two end plates. n- around the plasma column decreases with increasing magnetic field from 0.01 to 0.15 T. With increasing pressure from 0.25 to 1.1 Pa, n- around the plasma column gradually decreases.


"Sang Yod" is a red rice variety, good cooking quality, high nutrition and most popular among health-conscious consumers. Sang Yod has opaque and translucent endosperm of seeds occurring in the different proportion, both within and between population and the different growing area. The objective of this study was to evaluate grain quality characteristics and structure of opaque and translucent endosperm. Samples (22) of Sang Yod rice were collected from farmer's fields and planted to evaluate the proportion of opaque and translucent endosperm using physical and chemical characteristics, and endosperm structure under the scanning electron microscope (SEM). Opaque seed was thicker than translucent endosperm (1.59 and 1.55 mm, respectively). The 100 seed weight of translucent endosperm (1.50 g) was significantly heavier opaque endosperm (1.43 g) (p < 0.01). There were no differences in fat (11.32-11.40 %) and amylose content (5.38-5.50 %). The starch granule arrangement of translucent grain was more compact than opaque grain, starch granule size of translucent seed (3.09-10.04 µm) was bigger than opaque seed (2.66-9.49 µm) and had higher internal cavity than opaque seed. Therefore, differentiation of opaque and transparent weight will affect the commercial quality. The starch granule arrangement and gaps in starch structure may be related to the cooking quality, which should be further studied.


MOREIRA, F. L. In vitro metabolism study of the pentacyclic triterpene amyrins employing rat liver microsomes. 2013. 89 f. Master's thesis. Faculdade de Ciencias Farmaceuticas de Ribeirao PretoUniversidade de Sao Paulo, Ribeirao Preto, 2013. The isomers of pentacyclic triterpene amyrins (alpha and beta) occurring in a variety of plants, as Protium spruceanum. These molecules have showed significant pharmacological effects, as anti-inflammatory, gastroprotective and antitumor effects. Based on that, these substances have demonstrated great potential to become new drugs. However, the metabolic behavior by employing CYP enzymes (CYP450) has not been studied yet. The aim of this work was to perform an in vitro metabolism study by using these triterpenes and to determine the enzymatic kinetic parameters and possible metabolites by employing rat liver microsomes. To perform that, a bioanalytical method was developed and validated to analysis amyrins in rat microsomes. Gas chromatography coupled with mass spectrometer (GC-MS) was applied in the analysis. Liquid-liquid extraction was used to clean the sample and hexane was used as extraction solvent. Before metabolism studies, the method was validated according to current legislation to analysis of drugs in biological fluids. The following parameters were evaluated: linearity, sensitivity, selectivity, precision, accuracy, stability and recovery. All parameters evaluated were in agreement to legislation guidelines. After validation, enzymatic kinetic parameters were determined through variation of incubation time and concentration of microsomal proteins. By using linear range, the incubation time of 20 min and microsomal protein concentration of 0.25 mg mL were determined to respect V0 conditions. The enzymatic kinect results showed a sigmoidal profile. Thus, to calculate the kinetic parameters it was used the Hill equation. It was observed a Vmax = 0.698 ± 0.022 μmol/mg protein/min, S50 = 55.18 ± 10.5 μM and Hill coefficient of 2.7 ± 0.17 to alpha amyrin and a Vmax = 0.775 ± 0.034 μmol/mg protein/min, S50 = 130.4 ± 42.8 μM and Hill coefficient of 2.5 ± 0.21 to beta amyrin. The intrinsic clearance to beta and alpha amyrin was 3.05 mL/min/kg e 6.55 mL/min/kg, respectively. In spite of amyrins were metabolized by the CYP 450 enzymes, none metabolite was found. In this work, it was demonstrated, for the first time, the behavior of rat liver microsomes front to alpha and beta amyrin, in which it was observed an atypical behavior, that it does not follow the Michaelis-Menten kinetics.


After introducing Wigner Quantum Systems, we give a short re view of the one-dimensional Wigner Quantum Oscillator. Then we d efine the threedimensionalN-particle Wigner Quantum Oscillator, and its relation to th e Lie superalgebrasl(1|3N). In this framework (and first for N = 1), energy, coordinates, momentum and the angular momentum of the particles are inves t gated. Wigner Quantum Systems (WQSs) are quantum systems in which th e canonical commutation relations (CCRs) are replaced by a compatibility cond ition between the Heisenberg equations and Hamilton's equations. By dropping the CCRs, WQSs of fer a natural framework for quantum mechanics with non-commutative coordinates. H ere we consider in particular the three-dimensional N-particle Wigner Quantum Oscillator (WQO). As an introducto ry example, some properties of the one-dimensional WQO are review d, ith an emphasis on the different particle probability distributions (as compare d to the ordinary one-dimensional oscillator). For the three-dimensional N-particle WQO, a solution related to the Lie superalgebra sl(1|3N) is considered. For N = 1 we investigate the operators corresponding to coordinates, momentum and angular momentum of the particle in a cla ss of representation spaces. Remarkable properties include the discrete spectrum of coor dinate operators and their noncommutativity (and the same for the momentum operators). Th is has some unconventional consequences for the particle localisation. We compare som e of these properties with those of the canonical quantum oscillator (CQO). Finally, the case fo r generalN is described. Let Ĥ be the Hamiltonian of a system expressed in terms of the coord inates and momenta. This system is a WQS [1, 2] if all postulates of ordinary quantum mechanics hold, i.e. P1 The state space W is a Hilbert space. To every physical observable O there corresponds a Hermitian (self-adjoint) operator̂ O acting inW .


In ordinary language, number-words have a predominantly a<ljectival function. We say that the table has wooden legs, but equally well that it has four legs, or that the planets are nine, just as we say that they are spherical. The adjectival role of number-:-words in sentences like these encourages a view of number-words as functioning within a natural language as first-level predicates, and hence as standing for properties of the thing or things which the sentence is about. I would like to examine this natural and intuitive account of numbers, and the logical form of the sentences which ascribe them. It is a view which was advocated in the west by, amongst others, Mill and Husserl, and it is a view which has been developed in some detail by the Indian Nyaya-Vaise~ika school. However, what we might call the 'adjectival' account of number strikes many people nowadays as naive and implausible. This rejection of the account derives largely from Frege's sustained blistering attack in his The Foundations of Arithmetic, where he sets down a series of arguments all designed to show that number attributions cannot have the same logical form as the attribution of properties such as colour or shape. The main aim of this paper is to show that Frege's arguments against at least some versions of the adjectival account are unsound. In particular, I will try to demonstrate that they do not refute the later Nyaya theory, which appears to treat number-words as many-place relational expressions. A corollary is that the attempt to read the Nyaya theory as an anticipation ofFrege's own is mistaken.1


A new geophysical tool for high resolution subsurface imaging has been developed which has numerous applications in the field of hazardous waste management. The primary steps of the technique are: (1) An acoustic wave is projected through a subsurface cross section to a hydrophone array located vertically in a borehole; (2) the amplitude versus time signal of the propagating wave is collected at each hydrophone; and (3) the reduced wave equation and theory of backpropagation tomography are invoked to reconstruct the subsurface features from the collected data. The development of this emerging technology is highlighted beginning with its theoretical conception, through system development and field testing, to an examination of its future applications in environmental engineering.


Gender inequalities persist in the journalism industry in Hong Kong, as female journalists are seriously under-represented in the upper echelons of news organizations. Not unlike other countries, a major reason contributing to the phenomenon is the family–work tensions experienced by many female journalists, which lead many to leave the field at different stages in their lives. This study examines this problematic through the lens of Bourdieu's field theory. Individual journalists are seen as positioned in several overlapping fields in differentiated manners. Using survey and in-depth interviews, this study not only highlights the presence of structural inequalities in journalism and the pervasiveness of family–work tensions for female journalists, but also interrogates the conditions which allow some female journalists to handle work and family simultaneously and relatively successfully. We also discuss the implications of our findings for ways to tackle the problem of gender inequalities in journalism.


By using ammonium aluminium sulfate and ammonium hydro-carbonate as the starting materials, the synthesis of ammonium aluminium carbonate hydroxide (NH4AlO(OH)HCO3) wasstudied. It was found that NH4AlO(OH)HCO3 can be synthesized by adding ammonium aluminium sulfate solution to ammonium hydro--carbonate solution with a adding rate less than1.2L'h--1. Under other conditions the precipitate was γ-AIOOH in the experimental range. Thesequence of phase transformation of γ-AIOOH during heating was found to be γ--AIOOH → γAl2O3 → δ -Al2O3 → θ-Al2O3 →α-Al2O3, while that of NH4AlO(OH)HCO3 was found to beNH4AlO(OH)HCO3 →amorhous A12O3 → θ→Al2O3 →αA12O3. The transformation temperatures of NH4AlO(OH)HCO3 to θ-A12O3 and α-A12O3 were both about 100℃ lower than thoseofγ-AIOOH. γ-AIOOH can transform to α--A12O3 completely by calcining at 1200℃ for 1h, andthe obtained powder, with a particle size of 150um, can be sintered to 84.46% relative density at1450℃ for 2h. NH4AlO(OH)HCO3 can transform to α-A12O3 completely by calcining at 1100℃for 1h, and the obtained powder, with a particle size of 70um, can be sintered to 97.80% relativedensity under the same sintering condition.


− In the present research, in order to predict activity coefficient of inorganic ions in electrolyte solution of a petroleum system, we studied 13 components in the electrolyte solution, including H 2 O, CO 2 (aq), H, Na, Ba, Ca, Sr, Mg, SO 4 , CO 3 , OH, Cl, and HCO 3. To predict the activity coefficient of the components of the petroleum system (a solid/liquid equilibrium system), activity coefficient model of Extended UNIQUAC was studied, along with its adjustable parameters optimized based on a genetic algorithm. The total calculated error associated with optimizing the adjustable parameters of Extended UNIQUAC model considering the 13 components under study at three temperature levels (298.15, 323.15, and 373.15 K) using the genetic algorithm is found to be 0.07.


This review presents a comprehensive roadmap for the production of HMF from biomass and the upgradation of HMF toward fuels, chemicals and materials.


The object of the invention is a composition, particularly a pharmaceutical composition, in the form of a liquid preparation, which - in combination and in active, particularly pharmaceutically effective quantities - comprises (a) triclosane, and (b) at least one polyol. The composition according to the present invention is preferably suitable for the use as a blocking agent (blocking substance) for catheters, particularly urinary bladder catheters, wherein it counteracts particularly incrustations in long-term catheterizations.


2020 has been a year marked by a terrible pandemic, caused by a Coronavirus named Covid-19. This virus will go down in history for radically changing the world population's life habits and leading death, suffering and terrible moments among countless family, in addition to severe economic and financial damages. In just over a year and despite all the restrictive containment measures implemented by the the world countries' governments, the pandemic itself has caused over 163 million cases and 3 million global deaths, of which over 53 million cases and 1 million deaths i Europe, while in Italy there have been over 4 million cases and 123.000 deaths. The only way to stop pandemic is to be able to produce and test, as soon as possible, an effective vaccine to be given to the whole global population. Finally, in early 2021, the European Medicines Agency ( E.M.A.) and subsequently the Italian medicines agency ( IMA) approved to use various anti covid-19 vaccines produced by some pharmaceutical companies. In this context, the ASL NAPOLI 1 centro strategic direction, in compliance with state and regional provisions, promptly took action through the creation of numerous vaccination hubs with a dosing total capacity of 15.000-18.000 doses of vaccine per day, distributed throughout the area of competence. In particular, the vaccine centre set up in the rooms called "La fagianeria" located in the "real bosco di Capodimonte", a luxuriant park with various botanical wonders that covers about 134 hectares with over 400 different plant species. Just due to the location peculiarity, it was necessary to implement a pest control procedure according to the "UNI EN 16636:2015" standard, for infestations control and damages verification that pests can cause to the environment, to people's health and goods.The presence of endemic pests such as small rodents, crawling and winged insects or micro-organisms can represent, in fact, a serious risk for users health and health personnel since they can act as "vectors" for the introduction and the spreading of diseases and possible allergens for humans.Pest management, therefore, plays an important role in protecting public health and also in protecting health facilities from direct and indirect damages that can cause significant losses both in financial terms and in service quality offered to users. The study aim is to coordinate the "pest control" procedures implementation, verification and validation according to "UNI EN 16636:2015" at the vaccination center set up by ASL Napoli 1 centre in rooms called "la fagianeria" located inside the real bosco di Capodimonte, verifying their efficiency and effectiveness. The evolution of health care organisations towards socio-assistance intervention system characterised by a certain operational complexity, also through the multi-professional participation of various operators, has entailed the need to pay more attention to pay more attention to pest control activities to citizen users some quality healthcare services as a response to its ever-growing and more complex health demand, due to the progressive population ageing, which makes even more necessary a multitude of professional interventions, increasingly integrated, to ensure a compete and satisfying response.I would like to thank my company for giving me the chance to carry out this great professional experience that brought a cultural, behavioural and professional change in me. thanks also to the proactive attitude of the company strategic management which, in SARS-COV-2 pandemic emergency, has been able to integrate the work of various specialists among health health personnel, including "environmental and workplace prevention technician" and " specialist in prevention health professions sciences".


Any sort of process which produces output that can be measured periodically can be thought of as generating a flow of potential information into which a statistician can tap. Classical Shewhart methods can often help a statistician to identify local problems within the process associated with particular times, localities, people, etc.; or to spot system problems resulting in extreme variability or in discrepancies in central tendency from specifications. Other statistical techniques can identify trends over time, correlations, etc.; and surveys can be used to accomplish a variety of goals, including supplying information about consumer preferences. Despite these techniques and the latently rich source of information which together provide the potential for producing never-ending improvement in the process generating the information, results usually are disappoint ing. Experience has shown that perhaps 15 or 20 percent of the potential for improving a process lies in elimination of local problems, some of which can be accomplished by those working in the process. But the bulk of the improvement can be made" only by management in improving the system that generates the process. If we are talking about a survey, improving the system might mean improving the survey instrument and/or improving the overall training of those who administer the survey. Such improvements can initiate a shift in the process mean and a decrease in variability. There are two sorts of reasons why such improvements in the system fail to occur, and both involve top-level management. In the situation in which the process is in control, management does not take responsibility to bring about changes that statistical evidence implies are needed. When the process is not in control and, in fact,is in such a state of chaos that little can be learned about what is needed from using statistical methods, it is also up to management to clean up the chaos so that process control can be initiated. In the latter situation, the system generates so much noise that it is difficult to detect the signal. Instead of a normal distribution or a binomial distribution being generated by the measured output, one sees a mixture of several distributions, or perhaps some other distribution characteristic of certain out-of-control processes. For this situation there are barriers to productivity that need to be taken care of before the process can be brought under control, and even before statistical methods can be very helpful in bringing it under control. In a manufacturing process, these barriers might be uneven quality of materials, inherited defects, poor maintenance of machinery, defective tools or fuzzy operational job definitions. For a survey, there may be analogous sorts of barriers. For example, because of lack of integration of training, the expertise of those taking the survey, regarding the phrasing of certain critical questions, might be very uneven, or methods of dealing with nonrespondents may vary. If a control chart demonstrates other than a unimodal distribution with no more than a very few outliers, then one can safely infer not only that the process is out of control, but also that consideration should be given to the possibility of the existence of barriers of this type. Different sorts of situations in which local problems involving particular times, localities, individuals, etc. have been eliminated and the process has been brought under control, are like the states of chaos, in that it is impossible to make improvements in output without changing the overall system. Changing the system in this case requires a particular type of consciousness on the part of management. First, management needs some knowledge of what statistical analyses are telling them; and second, they need to feel a commitment to fine-tuning their system. Given these, of course, they need to take action or set activity into motion to enhance the workings of the process. Consumer research or investigation of the internal mechanisms of the system may tell them how to go about doing this. With the system under control, they usually will be able to make changes and measure responses to these changes without difficulty. After making such changes, statistical techniques can let them know if new local problems are appearing. If so, they can bring the system back into control and then continue to improve it. In order for this kind of process to begin, there must be a strong commitment on the part of top-level management.


In recent years, Vietnam's economy has been taking ongoing efforts to integrate into the international economy ISO 9000 series were introduced in Vietnam during 1990s and has been widely implemented in manufacturing sector and service sector. The number of Vietnamese companies which obtained ISO 9000 certification had increased 431 folds from 13 certificated companies in 1997 to 7333 certificated companies in 2009 [27]. While the majority of managers and researchers agree that ISO 9000 implementation is necessary for quality management process, the impacts of ISO 9000 implementation on companies' performance in Vietnam are still the questions for academicians and quality management practitioners and need to be investigated.


Several purine analogues are reported to show a teratogenic action in mammalian embryos when ad ministered at calculated dosage [reviewed by Giroud and Tuchmann-Duplessis-(1), Cahen (2) and Nishimura (3, 4); Kury et al. (5)]. We established that some methylated xanthines such as theophylline, theobromine and caffeine induce skeletal defects and subcutaneous hematoma in mice (6). Hypoxanthine also caused skeletal malformations and hematomas as well as the resorption of embryos (7). As methylated xanthines are also purine derivatives , it is of interest to study which, xanthine nucleus in


With more and more attention being paid to the Rootkits technology in the fields of cyber-security,various new Anti-rootkits technologies have emerged continually.Under the detection of various Anti-rootkits tools,the conventional Rootkits stealth technology is difficulty to play its role.Based on systematic analysis and research of traditional kernel-level Rootkits stealth technology,this paper presented a three-in-one rootkits stealth technical architecture on the basis of driver module integral transposition,kernel threads injection and IRP inline Hook in depth.Experimental results show that the Rootkits based on this stealth architecture can well bypass the detection of some well-known Anti-rootkits tools(such as Rootkit Unhooker and IceSword),which fully demonstrates the effectiveness of this three-in-one Rootkits stealth technical architecture.


Collaborative filtering (CF) is one of the most commonly used recommendation technologies in the recommender systems of e-commerce. However, due to the sparsity of users' rating data and the single ratings similarity, traditional CF algorithms show certain shortcomings. Aiming at these problems, a CF recommendation algorithm based on users' interests and the correlation of items is proposed. By using the algorithm, the similarity of users is measured according to users' interests based on the categorical attributes of items, while that of items is computed by introducing the association rules of data mining. The results of the tests on Movielens dataset manifest that the modified algorithm presents higher recommendation accuracy than the traditional CF algorithms.


The symposium Bibliometrics: Use and Abuse in the Review of Research Performance, held in Stockholm, 23–25 May 2013, fell within the context of an initiative to put an end to the misuse of JIF (journal impact factors), embodied in the San Francisco DORA (Declaration on Research Assessment) [1] instigated in December 2012 at the meeting of the American Society for Cell Biology. Interestingly, just before the start of the Symposium, reactions to DORA appeared in leading journals and news blogs, such as Nature News Blog [2], an editorial in Science [3], an editorial on research assessment in The EMBO Journal [4], an editorial in Molecular Biology of the Cell [5] and an editorial in eLIFE [6], to name but a few. In a sense, DORA can be seen as a kind of culmination of decades‐long discussions on bibliometrics, their use and abuse. Debates on the JIF also have a history of discussions as evidenced in leading journals as mentioned above, discussions pro and contra the JIF often mirroring divergent views (cf. e.g. [7]). In principle, the reactions to DORA can be said to support the main intent of the declaration, that is to address the over‐reliance on JIFs in research assessment, as well as providing the basis for a change in the current system of research assessment prevalent in the so‐called hard sciences. It is of course impossible to go into the different nuances that the above‐mentioned reactions to DORA stress. However, it should be noted that up to a certain point, they present a range of opinions and that they focus on different points of the declaration. One example is the view of the Nature [2], which has not signed DORA, and in which Philip Campbell, Editor‐in‐Chief of Nature, stresses that the group's journals had in the past published many critical views on the excessive use of JIFs. He also states the opinion that some statements in DORA are too sweeping, and thus does not merit the full support of DORA. Although DORA can be seen as a move in the right direction, for if nothing else it has in a strong way initiated once again the big question of how to assess research performance, in order to assess quality and not peripheral indicators, open questions still remain. Would reducing the 'impact' of JIFs in favour of article‐level ones be a true improvement in assessing article quality? Or, should the ultimate goal be evaluating research papers on the basis of their scientific merit? The ongoing discussions will, if nothing else, hopefully lay the foundations for a


This article approaches the mass protest of Trelewazo in October 1972, understood it as a regional expression of the class struggle process of the period, and in particular, as the combined result of both the accelerated industrialization process and the incorporation of the region into the general repressive circuit. Both processes gave rise to new social relations, stimulating a growing politicization whose deliberative and organizational "gymnastics" (in assemblies and commissions) is essential to understand the dynamics of the protest. The "Vigilant Operation" led to the alignment of the political forces that opposed the regime, around a central demand articulated them: the freedom of political prisoners and the defense of human rights.


HIRFL-CSRm will accelerate the proton beam up to 2.8 GeV. The interesting physics, such as the hadron spectrum, di-baryon state and the rare decay mode of the neutral mesons can be investigated with such beams. The corresponding detector as introduced in Ref.[1] is an internal-target 4π detector which is composed of the forward detector (including position detector and hadron calorimeter) to detect particles emitted at forward angles, and the center detector (including tracker, plastic scintillator barrel and EM calorimeter) to measure momentum and energy loss of the charged particle, and the energy and emission angle of the high energy photon at central and backward angles. To design such a complex detector, the Monte-Carlo (MC) simulation is definitely necessary.


In order to find out new ore bodies and increase exploitation reserves, a economic exploration means is strongly needed in old mines. VLF-EM (very low-frequency electromagnetism) is a suitable mean to resolve problems. By means of exploration data processing, combined with the laws of exploration, it is confirmed that VLF-EM method can disclose the occurrence of abnormity body and confirm the place and distribution of ore bodies in the appropriate geology and geophysics regions suitable to use VLF-EM. VLF-EM method can be a guideline for the deep ore exploration.


This article offers an analysis of the relationship between policy and the system of managing public affairs. The author attempts to demonstrate that the traditional ideal of an apolitical public administration is being significantly eroded. Changes occurring both in the public administration itself, as well as in its environment, have caused the activities of the public administration activism to become much more political in character. The public administration constitutes an increasingly significant element in the management of public affairs. Its increasing importance has been accompanied by a simultaneous limitation on the influence of political institutions not only in the formulation of public policy but also in the manner of its implementation. A logical consequence of this is increasingly incoherence, resulting from the fact that practices used by the public administration are increasingly at odds with the classical (and, formally, still binding) rules governing its actions. (original abstract)


There is an ample debate over the quality of Free/Libre Open Source Software FLOSS with mixed research results. The authors show that a reason for these mixed results is that quality is being defined, measured, and evaluated differently. They report the most popular approaches including software structure measures, process measures, and maturity assessment models. The way researchers have built their samples has also contributed to the mixed results with different project properties being considered and ignored. Because FLOSS projects evolve with each release, their quality does too, and it must be measured using metrics that take into account their communities' commitment to quality rather than just the structure of the resulting code. Challenges exist in defining what constitutes a defect or bug, and the role of modularity in affecting FLOSS quality. The authors suggest three considerations for future research on FLOSS quality models: 1 defect resolution rate, 2 kind of software product, and 3 modularity-both technical and organizational.


Discourses on 'informality' in South Asia typically refrain from providing
 historical context or emphasise postcolonial history. Its historical
 antecedents in economic interaction are strongly related to colonial
 attempts to 'formalise' the economy as part of a project of 'modernisation',
 however, and the responses by economic actors seeking to cope with, or
 evade, the direction of this colonial endeavour. Partially, these actors
 made use in these attempts of prevalent socio-economic structures frequently
 summarised under the rubric of the bazaar economy. Yet the encounter with
 colonial 'modernity' also encompassed reinterpretations and reimaginations
 of economic interaction. This chapter studies the historical development of
 'informality' by observing patterns in late colonial commercial, financial,
 and labour markets.


Issues are considered that are associated with the determination of dynamic loads encountered in moving units of the planetary mill. A horizontal planetary mill was chosen for compiling a dynamic model, as it has a great potential for organizing a closed grinding cycle with continuous loading and unloading of material. Calculation schemes were drawn up in moving units at the moments of the beginning of its operation and the steady movement of the grinding drums. Using the d'Alembert principle, taking into account the geometric parameters of the grinding unit, the reduced moments of inertia and moments of forces, as well as the acceleration time from a state of rest until the carrier reached a steady angular velocity, were determined. From the condition of equality of the power of the reduced moment of forces acting on the link of reduction, and the power of all forces and moments applied to the links of the planetary mill, the initial torque applied to the carrier was determined, which is necessary in the future to determine the power expended both at the moment of starting the mill, and at the time of its stable operation. It is shown that the initial torque depends on the value of the initial angular acceleration, which, in turn, can be different depending on the accepted law for changing the angular acceleration and the acceleration time to the required angular velocity of steady motion. It is also indicated that during the start-up period, the power supplied to the mill is spent on accelerating the rotation of the leading link and on overcoming various resistances such as friction forces in the units of the carrier and grinding drums.


Purpose - The aim of this paper is to increase the understanding of foreign market entry among SMEs. The model of a French established company entering the Scandinavian market supports this researc ...


This paper offers a new paradigm for describing deployed naval systems. Acquisition reform, while encouraging the Department of Defense to be more dependent on industry, recognizes the important government role of ownership and accountability in acquiring things. Warfare systems are no exception. One of the factors to be considered is how the deployed force will use the warfare system. This perception, or mental image, is one view of the deployed force; that is, the viewpoint of the Defense acquisition community. This viewpoint is characterized by the concept that people are part of the warfare system and that the system components require human-machine interfaces. This concept is the result of the evolution of automation that has required attention to be given to the detailed design of computer controlled machines. Collectively the people composing the deployed force-the Sailor-accomplish assigned missions by using machines to extend the physical and mental capabilities of humans. The Sailor's mental image, or viewpoint, is one of people trained to use machines as an extension of themselves. Thus, the acquisition community and the Sailor have different viewpoints of the deployed force in terms of the role of automated machines. This paper explores the relationship of these two viewpoints to each other and to the deployed force as a whole.


____________________________________________________________ The extensive use of pesticides to protect agricultural crops necessitates reliable tools for the detection of residues in food and water, thus ensuring environmental protection and consumer safety. Neuroinhibitors such as organophosphates and carbamates are widely used in agriculture because of their high insecticidal activity and their rapid mineralisation in the environment. Since they do not only inhibit insect acetylcholinesterase (AChE) but also interfere with neural transmission in other organism, including humans, they represent a potential hazard for human health and environmental food chains, and thus require continuous assessment. Recent reports on organophosphate contamination in baby food have initiated the reassessment of permitted residual concentrations of these compounds in view of the US Food Quality Protection Act. Here we present a rapid detection method for neurotoxins in food, which can increase the number of tested foodstuff and thus improve the consumer safety. We developed a highly sensitive and rapid food analysis biosensor based on disposable screen-printed thickfilm electrodes [1, 2]. Matrix problems were solved by using isooctane as extraction solvent. The performance of this amperometric test was checked by three different food matrixes, namely orange juice, apple and peach baby food. The detection limit was comparable to chemical standard methods and met the requirements for monitoring the maximum residue levels in baby food set by the EU. As such screening tests use a large amount of enzyme a production of recombinant acetylcholinesterase is strongly promoted. A promising expression system is the yeast


Abstract : Autonomous and transportation energetics in the near future will require the development of new sources of electrical energy: thermoemission generators. The book is devoted to a popular presentation of the operating principles and hardware of thermoemission generators. The book is intended for a wide class of readers interested in problems of direct conversion of thermal and nuclear energy into electrical energy and in the advantages and fields of application of these generators of electrical energy. (Author)


This case provides opportunities for students to think more deeply about tensions that arise in the pre-service teacher (PST)-mentor teacher-supervisor triad when there are competing views about responsive instruction for Latinx students. Furthermore, this case illustrates how shared social identities among triad members do not necessarily mean there is a shared stance of how to work with Latinx students that aligns with research-based recommendations. The accompanying teaching notes, discussion questions, and classroom activities expose students to relevant literature, introduce them to the concept of courageous conversations, and enable them to role play.


AMERICAN ASTRONOMICAL SOCIETY MEETINGMINNEAPOLIS, MINNESOTA-- A small meeting of about 680 astronomers here 29 May to 2 June featured some big claims about the ingredients of comets.


CONTEXT
An imbalance between shoulder internal rotation (IR) and external rotation (ER) strength in athletes is proposed to increase the risk of sustaining a shoulder injury. Hand-held (HHD) and externally fixed dynamometry are reliable forms of assessing shoulder IR and ER strength. A new externally fixed device with an attachable fixed upper-limb mold (The ForceFrame) exists; however, its reliability in measuring shoulder strength is yet to be investigated.

OBJECTIVE
To determine the test-retest reliability of the ForceFrame, with and without the fixed upper-limb mold, in the assessment of shoulder IR and ER strength, as compared with HHD.

DESIGN
Test-retest reliability study.

SETTING
Laboratory, clinical.

PARTICIPANTS
Twenty-two healthy and active individuals were recruited from the university community and a private physiotherapy practice.

MAIN OUTCOME MEASURES
Maximal isometric shoulder IR and ER strength was measured using the ForceFrame and traditional HHD in neutral and at 90° shoulder abduction. Mean (SD) strength measures were calculated. Test-retest reliability was analyzed using intraclass correlation coefficients (3, 1). The SEM and minimal detectable change were calculated.

RESULTS
Good to excellent test-retest reliability was found for all shoulder strength tests across Hand-held dynamometry (HHD) and externally fixed dynamometry (EFD) are reliable forms (intraclass correlation coefficients [3, 1] = .854-.916). The minimal detectable changes ranged between 25.61 and 41.84 N across tests. Test-retest reliability was not affected by the dynamometer or testing position.

CONCLUSIONS
The results from this study indicate that both the ForceFrame and HHD are suitable for measuring shoulder strength in clinical practice. The use of the fixed upper-limb mold with the ForceFrame does not improve reliability.


This is a study on how Cheoyong and Cheoyong Story have been accepted by writers for their poetry. Cheoyong and his story which was introduced in the Heritage of the Three States were handed down to posterity, translated liberally and rewritten as in the song of 'So-ak-bu' by Yi Je-hyun in the latt...


Study the effect of guided inquiry learning model to the cognitive achievement of students in SMA Negeri 01 Manokwari (study on the subject of solubility and solubility product) which aimed to determine whether there is a significant difference between the learning model of guided inquiry and conventional learning model to cognitive achievement of students and to measure the percent effect of both models was carried out. This study used research quasi-experimental design with the pretest-posttest design. Mechanical sampling was done by purposive sampling. The instrument used to measure cognitive achievement of students is a test essay. Analysis of the data used is descriptive analysis and inferential using the software SPSS 22. The results showed that there were differences in the results of a cognitive learning which the guided inquiry learning model is better than the conventional learning model with the effect is 29,49 percent.


In experimental researches of waves and ice effects on hydraulic structures the special attention it is necessary to spare to the problems of modeling of wave and ice processes with the purpose of receipt of reliable results.


During the measurement by scanning near-field optical microscope (SNOM), it is found that edge effect is prone to occur. This paper uses the aluminum (Al) atoms of FCC structure to arrange the atomic model of the measurement of SNOM, and use Morse potential to calculate the tip-sample atomic interaction, and combines the vibration theory for the optical fiber tip, to construct a fixed amplitude simulative model for measuring SNOM. And according to this simulation measure obtained result. It implies that a sharper probe can produce fewer effects on the edge effect. In the comparison between the result of simulative measurement and that of real scanning and measurement, it is proved that the simulative measuring model for the nano-scale standard sample of SNOM constructed by this paper is reasonable.


Farnesol interacts with Candida albicans as both a quorum sensing molecule and toxic agent, but confusion abounds regarding which conditions promote these distinct responses. Farnesol sensitivity was measured when inoculum cell history and size, temperature, and media were altered. Parameters for farnesol tolerance/sensitivity are defined, validating previous studies and identifying new variables, such as energy sources. This study provides a clear understanding of what farnesol concentrations are lethal to C. albicans, based on environmental conditions.


This article discusses the implications of the materiality of the app-book in the reading experience, recognizing actors who impose the updating of the reading protocols proposed by Chartier. Starting from the nature of digital book media, the article proceeds by presenting the system protocols, in the reading and in the space. Conceptual operators of bookish literature and media are articulated, especially notions about the reading protocols and the computational pragmatics of new media. Of an exploratory approach, from a literature review, the article points to results that indicate the nature of the media as a drive source of protocols that place materiality as the central point of reading transformations in a digital environment.


In the current study, we investigated the influences of chemical vapor deposition parameters on the formation of uniform structures of few- and multi-layer graphene (FLG and MLG) as a coating phase on carbon fiber (CF). To this end, the process conditions of the chemical vapor deposition method, such as catalyst concentration, reaction temperature and time, and also carbon source flow rate, were optimized. The resulting FLG and MLG with high yields led to the modification of the CF surface by improving its properties. By applying scanning electronic microscopy, transmission electron microscopy and Raman spectroscopy, the surface morphology and structural information of the G–CF were analyzed. It was observed that under different conditions the FLG–CF and MLG–CF were obtained with 54%, 58% yields and also 10.21 m2 g−1, 8.78 m2 g−1 BET surface areas, respectively. Besides that, the FLG–CF and MLG–CF were used as fillers in the polypropylene (PP) composite and the effects of the number of graphene layers on the mechanical and thermal properties of the composite were analyzed. It is noteworthy to mention, composites based on the CF coated with G with only a few layers presented the highest surface area, strength and thermal resistance compared to those based on multi layers.


Describes Cumbria in terms of its people, economy and geography, noting the various problems the region faces. Relates plans to link Cumbria's communities electronically for the twenty‐first century. Details these plans in terms of the linking ‐ via an electronic information highway ‐ of local communities and individuals with such elements as district, town and parish councils; public libraries; village halls; community centres; and the holdings of a "people's" university, developed as a key part of these plans.


Recently, we reported on novel membrane specializations, referred as tubulohelical membrane arrays (TUHMAs). Could they possibly have a wider impact on cellular processes? For answering this question the examination of their close ties with annulate lamellae (AL) is crucial. A recherche of previous publications, however, made us aware of difficulties in distinguishing between both nucleoporin-containing cytoplasmic membrane configurations. Overlooking the individual characteristics of TUHMAs seems to have led to their assimilation as AL, in the past. Nowadays, progress in both sample preparation and electron microscopic 3D-visualization has narrowed the latitude for controversial interpretation. In consequence, the incompatibility of TUHMAs with the definition of the AL proper becomes apparent. Here, we provide a guideline how to distinguish between both entities, including cancerous conditions of cells that may lead to aberrations. With respect to TUHMAs, we emphasize those observations, which are not typical for AL, and which would not have met the interest of previous research on this topic. Elucidation of the initial observations related to TUHMAs in a common context with AL, perhaps, could help overcoming the current deadlock in research on AL.


Explosive contamination in soil is a great concern for environmental health. Following 50 years of munitions manufacturing and loading, soils from two different sites contained ≥ 6,435 mg 2,4,6-trinitrotoluene (TNT), 2,933 mg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and 2,135 mg octahydrol-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) kg− 1 soil. Extractable nitrate-N was as high as 315 and ammonium-N reached 150 mg N kg− 1 soil. Water leachates in the highly contaminated soils showed near saturation levels of TNT and RDX, suggesting great risk to water quality. The long-term contamination resulted in undetectable fungal populations and as low as 180 bacterial colony forming units (CFU) g–1 soil. In the most severely contaminated soil, dehydrogenase activity was undetectable and microbial biomass carbon was very low (< 3.4 mg C mic kg–1 soil). The diminished biological activity was a consequence of long-term contamination because short-term (14 d) contamination of TNT at up to 5000 mg TNT kg–1 soil did not cause a decline in the culturable bacterial population. Natural attenuation may not be a feasible remediation strategy in soils with long-term contamination by high concentrations of explosives.


In order to contribute to the improvement of brain infarction management in Brazzaville, a cross-sectional and analytical study with prospective data collection was conducted in the cardiology and neurology departments of the Brazzaville University Hospital, from February 1 to July 31, 2018. It included patients hospitalized for cerebral infarction confirmed with imaging, and having done an etiological assessment with at least one electrocardiogram at rest and one of long duration. Among these 138 patients included, 11 had atrial fibrillation, equaling a frequency of 7.9%. The mean age of AF patients was 71 ± 8.8 years. The cardiovascular risk factors found were hypertension in eight cases (72.7%), diabetes in five cases (45.5%), abdominal obesity in four cases (36.4%). AF was permanent in 10 cases (91%), and paroxysmal in one case (9%). It was valvular in three cases (27.3%) and non-valvular in eight cases (72.7%). The cardiopathy involved was hypertensive in seven cases (63.6%), ischemic and valvular in two cases each. The CHA2DS2-VASc score, calculated in eight patients, was an average of 2.2, and ≥2 in more than 80% of patients; HAS-BLED score of 2.4 on average was ≥ 3 in more than 72% of patients. Digoxin was prescribed in seven cases (63.6%) and an anti-vitamin K in eight cases (72.7%). In multivariate analysis, age (OR = 20.10, p = 0.023), arterial hypertension (OR = 23.82, p = 0.011), and dyslipidemia (OR = 2.03, p = 0.032) were the predictive factors found. AF is infrequent during brain infarction in Brazzaville. This systematic research raises the problem of age in our context.


The present invention preparation step of preparing a hard contact lens and the centering jig and a printing composition relates to a printing method of a color hard contact lenses for printing an iris pattern on the entire surface of the hard contact lens, so as to print the iris pattern to the hard contact lens and characterized in that it comprises a processing step after the processing and after the printing, the printing method comprising: an iris pattern, an iris pattern printed hard contact lenses, hard contact lenses with the compositions for printing by mounting the centering jig. Thus, the present invention is by printing the iris patterns of various colors and patterns using the composition for printing on the front outer circumference of the hard contact lens, a colored hard contact lens having a front iris patterns of various colors and patterns on the hard contact lenses It provides an effect that can be produced.


The basic meaning and the main method of data mining are introduced,application of data mining in teaching evaluation system is discussed and the relationship between data is found according to data evaluating class teaching qualities by students to offer scientific basis to evaluation of college class teaching quality.


Conceptual design of the pantograph for high speed trains of 350㎞/h is introduced. The aims to be accomplished in the concept design are the good dynamic performance, low noise, aero-dynamic stability. The resulting mechanism of the pantograph have single-arm type structure with bebel gears to reduce noise sources, symmetric structure for the aero-dynamic stability and the special panhead assembly to obtain good dynamic performances.


We analyze amplitude squeezing from a singly resonant frequency-doubling laser oscillating at a single frequency. In this laser system, the cavity loss depends on the intensity of the oscillating fundamental field, so that conventional analyses based on a mean-field approximation become invalid in a highly pumped regime. To avoid this inconvenience, we consider spatial evolution of fields both in a laser medium and in a nonlinear crystal. It is predicted for the first time that a combination of excess nonlinearity and modest laser saturation can increase the output noise. We propose novel indices to evaluate the possible noise enhancement and suggest a design rule for squeezed light generation.


The upcoming age of information and technology requires higher schools' journals to face the challenges while enjoying the conveniences at the same time.Information and standardization should be the direction we are headed as a journal has already become a symbol of the school speaking for itself.


The access of a high proportion of distributed photovoltaic has brought challenges to the economic and safe operation of distribution networks. Aiming at solving insufficient photovoltaic absorption and low equipment utilization efficiency of the distribution networks, an optimal configuration method of tie switch considering multi-criteria matching of distribution lines is proposed. Matching criteria of distribution lines are put forward according to net load curve correlation, net load magnitude and net load curve segmentation. A two-layer optimal configuration model of tie switch between matched distribution lines is established, the upper-level model takes the investment cost and network loss cost as objective functions, and the lower-level model takes the operating cost and degree of load balancing as objective functions. A hybrid algorithm combining improved genetic algorithm and second-order cone programming method is used to solve the problem. The simulation results show that the optimal configuration of tie switch based on the multi-criteria matching of distribution lines can improve the photovoltaic absorption and equipment utilization efficiency, and ensure the economic and safe operation of the distribution networks.


Genome scale metabolic modelling is widely used technique to research metabolism impacts on organism's properties. Additional omics data integration enables a more precise genotype-phenotype analysis for biotechnology, medicine and life sciences. Transcriptome data amounts rapidly increase each year. Many transcriptome analysis tools with integrated genome scale metabolic modelling are proposed. But these tools have own restrictions, compatibility issues and the necessity of previous experience and advanced user skills. We have analysed and classified published tools, summarized possible transcriptome pre-processing, and analysis methods and implemented them in the new transcriptome analysis tool IgemRNA. Tool novelty is the possibility of transcriptomics data pre-processing approach, analysis of transcriptome with or without genome scale metabolic models and different thresholding and gene mapping approach availability. In comparison with usual Gene set enrichment analysis methods, IgemRNA options provide additional transcriptome data validation, where minimal metabolic network connectivity and flux requirements are met. IgemRNA allows to process transcriptome datasets, compare data between different phenotypes, execute multiple analysis and data filtering functions. All this is done via graphical user interface. IgemRNA is compatible with Cobra Toolbox 3.0 and uses some of its functions for genome scale metabolic model optimization tasks. IgemRNA is open access software available at https://github.com/BigDataInSilicoBiologyGroup/IgemRNA.


The general objective of the PRC Line Pipe Research program from 1953 to 1962 has been to obtain the highest quality pipe possible within economic limits. The results of research conducted during this nine year period was presented to at an industry seminar in March 1961. This report provides documentation of the presentations provided at the seminar. It is designed to acquaint the pipeline engineer with the research that was carried out and the results obtained to date.The scope of the study includes the following: the basic fracture mechanics in steel, investigation of the effect of manufacturing variables on pipe properties, full-scale fracture characteristics, and development of laboratory tests for indicating performance characteristics. Also included in the program are several new types of high-strength line pipe.


T HIS conference was presented at Cook County Hospital, Chicago, Illinois, on February 20, 1955, as one of the regular weekly clinical-pathologic exercises of the Hospital. The conferences are modeled after the Cabot prototype, the case being presented by the clinicians as an unknown for discussion. In order to preserve the spirit and spontaneity of the original conference, editing has been limited largely to making the material more suitable for publication, selection of pertinent photomicrographs for reproduction, and documentation of pathologic interpretations by appropriate references.


Vehicle bodies are designed and manufactured to provide the occupants with an adequate level of protection by maintaining the integrity of the passenger compartment, and assuring, at the same time, that the crash deceleration pulse stays below the biomechanical limits of the human tolerance. Therefore, the target of crashworthiness studies is an optimised vehicle structure with controlled deformation zones in order to maintain sufficient space inside the passenger cell. In particular, during a side crash, mainly the cross beam structures of the passenger compartment and also the high-strength beaded floor sheet plates can be utilised for supporting and energy absorption. This paper presents the improvement of lateral vehicle crashworthiness achieved by implementing a tube oriented design. A ring-shaped component, which is basically a circular cross-section extruded profile supporting the B-pillars, roof and floor, is designed and implemented in a numerical model of a typical sedan shaped vehicle. The numerical assessment of the proposed solution is performed according to the "Euro NCAP Side Impact Testing Protocol" using LS-Dyna explicit code and Madymo for occupant simulations. Comparative results are presented in terms of intrusions into the passenger cell and loads on the occupant dummy EuroSID-2. Relevant injury criteria are analysed and processed into the side impact score specified by the "Euro NCAP Assessment Protocol". Furthermore, particular importance has to be attributed to weight reduction during the development phase because of the significant contribution of vehicle mass to driving resistance and emissions. Hence, lightweight materials are also implemented for the ring structure. The results obtained from the side impact simulations of the new developed solution are compared to the ones with the steel ring component


Non‐noble bimetallic alloys serve as an alternative catalytic material for noble metal‐based catalysts that could be applied in selective hydrogenation of unsaturated compounds. However, maintaining the catalytic stability for bimetallic nanoparticles in the selective hydrogenation process remains a substantial challenge, due to its high tendency to structural transformation upon reactive circumstances. Herein, this problem is solved by constructing carbon‐protected catalytic sites within carbon layer‐coated Ni−Fe nanoalloy composite via pyrolysis of NiFex(OH)2/glucose precursor. The optimized NiFe0.06@C catalyst exhibits excellent stability and selectivity to aminostyrene (>97 %) in the chemoselectivity hydrogenation of 3‐nitrostyrene reaction. Various characterization indicates that the enhancement in stability originates from the protective effect of the carbon layer, which prevents the oxidation and aggregation of Ni−Fe nanoparticles during the reaction process. This work greatly advances non‐noble metal‐catalyzed selective hydrogenation of nitroarenes and helps the rational design of bimetallic catalysts.


added wires exhibit lower values than ternary wires with the same nominal C content, suggesting a higher C content in the phase. The "disorder" in the structure has been characterized as a partial substitution of B by Carbon. A reduction of the domain sizes in the direction as well as in-plane to 250 and 124 has been determined from the FWHM and the breath values of the (110) and (002) peaks. With the simultaneous introduction of , a strong improvement of and has been obtained with respect to additions. A further enhancement of is expected when using different combinations of additives with and without Carbon, aiming for a further raise of in wires with multiple additives, as a result of the combination of different mechanisms.


Despite the proliferation of institutional schooling during this century, voluntary home-based education is a growing phenomenon in a number of western countries (eg. Australia, Britain, Canada, New Zealand, United States) (Mayberry et al, 1995; Meighan, 1995; Hunter, 1994). Parents who choose to "homeschool" do so for a number of reasons and pursue a variety of methods. An emerging body of research has investigated the reasons parents give for homeschooling, but little of the research literature has to date looked at children's perceptions of their home-based education experiences. This paper reports on interviews, conducted in 1998, with a number of young children who were asked about their perceptions of their home-based education. Their voices indicate that they view homeschooling favourably. Institutional schooling, viewed today as the normal process of education for the masses has not always been available The educational norm for pre-industrial societies was home education, yet today it is often viewed as an aberration. Current research evidence suggests homeschooling can be a viable educational alternative, worthy of serious consideration by policy makers, educational professionals and researchers. With the increasing evidence that the youth of today are finding school less relevant to their lives, policy-makers should be considering alternatives in order to cater to individual needs. Homeschooling can incorporate teaching strategies that have long been held to be educationally effective vertical age grouping, one-on-one tuition, peer tutoring, supportive child-adult relationships, child-centred and initiated learning. These strategies can involve a child cognitively in their own learning, yet these strategies are hard to pursue in institutional settings. This paper suggests how we may bridge the divide that currently exists between home-based education and institutional schooling in order to bring benefits to children and families alike as we head towards the


Elastin‐derived peptides were previously shown to influence human skin fibroblasts (HSF) chemotaxis and proliferation (Ghuysen et al., 1992). We report here that culturing HSF on κ‐elastin (κE) but not onto fibronectin (FN) enhanced the secretion of latent elastinolytic activity. The proteinase involved was identified as the 72 kDa gelatinase A. Moreover, HSF‐κE as well as HSF‐FN interactions modulated the secretions of Il1 induced expressions of elastinolytic activities.


The 1,3-dipolar cycloaddition reaction of isoquinolinium ylides to nitrostilbenes provides an approach to 1,2-diarylpyrrolo[2,1-a]isoquinolinium-3-carboxylates and then to a complete hexacyclic lamellarin core.


Digital design has emerged as a transformative force in higher education, reshaping the way students learn and educators teach. This abstract highlights the significance of digital design in higher education and its potential prospects for the future of learning Digital design encompasses a wide range of visual content creation using digital tools, such as graphic design, web design, animation, and multimedia production. digital design offers personalized learning opportunities, enhances engagement, and prepares students for success in a technology-driven world. Despite its potential, challenges remain. Digital literacy among faculty and students, technological infrastructure, quality assurance, and data security are critical considerations for successful implementation in higher education. In conclusion, digital design holds tremendous promise for higher education, offering opportunities for innovation, cost-effectiveness, and improved learning outcomes. Embracing digital design can prepare students for a technology-driven world and equip them with essential skills to thrive in a rapidly evolving job market. As higher education institutions invest in digital design, they can create the way for a transformative and inclusive learning landscape, shaping a brighter future for learners and educators alike. In this study, we will use critical and content analysis to uncover challenges and opportunities in higher education for digital design course implementation. Using a questionnaire of 200 students taking this course at their university and 200 students not taking the digital design course, the study will aim to identify the advantages and disadvantages of both two. We also explored the advantages of universities that have this course in them


Along with the development of computer networks and applications,distributed component technology became the hotspot of distributed computing.CCM is one of the popular distributed component technologies.Analyzes CORBA component model(CCM) which defines not only the services it provides but also the services it required.So CORBA components can be assembled via their ports. It applies the mechanism of the component assembly based on CCM in the supply chain management of the PLM.This new kind of connective component realizes the distributed component's plus and play,so it builds the SCM which has platform-independence and easy to replant.


High-order accurate schemes for conservation laws for unstructured meshes are not nearly so well advanced as such schemes for structured meshes. Consequently, little or nothing is known about the possible practical advantages of high-order discretization on unstructured meshes. This article is part of an ongoing effort to develop high-order schemes for unstructured meshes to the point where meaningful information can be obtained about the trade-offs involved in using spatial discretizations of higher than second-order accuracy on unstructured meshes. This article describes a high-order accurate ENO reconstruction scheme, called DD-L{sub 2}-ENO, for use with vertex-centered upwind flow solution algorithms on unstructured meshes. The solution of conservation equations in this context can be broken naturally into three phases: (1) solution reconstruction, in which a polynomial approximation of the solution is obtained in each control volume. (2) Flux integration around each control volume, using an appropriate flux function and a quadrature rule with accuracy commensurate with that of the reconstruction. (3) Time evolution, which may be implicit, explicit, multigrid, or some hybrid.


The notion of the almost Hermitian Finsler manifold admitting an almost complex structure $f^i_j(x)$ was, for the first time, introduced by G. B. Rizza [8]. It is known that the almost Hermitian Finsler manifold (or a Rizza manifold) has been studied by Y. Ichijyo [2] and H. Hukui [1]. In those papers, the almost Hermitian Finsler manifold which the h-covariant derivative of the almost complex structure $f^i_j(x)$ with respect to the Cartan's Finsler connection vanishes was defined as the Kaehlerian Finsler manifold. The nearly Kaehlerian Finsler manifold was defined and studied by the former of authors [7]. The present paper is the continued study of above paper.


The apparatus and method of the present invention is that for encoding the wavelet tree in a wavelet coding technique, the technique is thereby addressing both the balanced and unbalanced wavelet tree, increases the overall coding efficiency.


In this work a method is proposed to allow the indirect orientation of images using photogrammetric control extracted through integration of data derived from Photogrammetry and Light Detection and Ranging (LiDAR) system. The photogrammetric control is obtained by using an inverse photogrammetric model, which allows the projection of image space straight lines onto the object space.  his mathematical model is developed based on the intersection between the collinearity-based straight line and a DSM of region, derived from LiDAR data. The mathematical model used in the indirect orientation of the image is known as the model of equivalent t planes. This mathematical model is based on the equivalence between the vector normal to the projection plane in  the image space and to the vector normal to the rotated projection plane in the object space. The goal of this work is to verify the quality, efficiency and potential of photogrammetric control straight lines obtained with proposed method applied to the indirect orientation of images. The quality of generated photogrammetric control was statistically available and the results showed that proposed method is promising and it has potential for the indirect orientation of images.


The antioxidant function in liver of ducks infected by Salmonella Enteritidis and the effect of the antioxidant function after medication were studied here. The activity of antioxidant enxyme and content of MDA were measured in liver of ducks. The results indicated that the activity of SOD was increased obviously (P0.01) in 12 and 36 hours and reduced obviously (P0.05) in 60 hours. POD and CAT were increased obviously (P0.05 or P0.01) in 36 and 60 hours and the content of MDA increased obviously (P0.05) in 12 hours and reduced later but not obviously (P0.05). This explained the antioxidant function of liver occurred unusual change infected. At the same time, the antioxidant function of liver was increased after curing with oral intake of florfenicol or Chinese herbal medicine preparation a certain extent. The results explained that the antioxidant enxyme participated in the process of resisting Salmonella Enteritidis in liver.


Compact heat exchangers are well known for their ability to transfer a large amount of heat while retaining low volume and weight. The purpose of this paper is to study the potential of using this device as a chemical reactor, generally called a heat exchanger-reactor (HEX reactor). Indeed, the question arises: can these geometries combine heat transfer and mixing in the same device? Such a technology would offer many potential advantages, such as better reaction control (through the thermal aspect), improved selectivity (through intensified mixing, more isothermal operation and shorter residence time, and sharper RTDs), byproduct reduction, and enhanced safety. Several geometries of compact heat exchanger based on turbulence generation are available. This paper focuses on one type: vortex generators. The main objective is to contribute to the determination of turbulent flow inside various geometries by computational fluid dynamics methods. These enhanced industrial geometries are studied in terms of their thermal-hydraulic performance and macro-/micro-mixing ability. The longitudinal vortices they generate in a channel flow turn the flow perpendicular to the main flow direction and enhance mixing between the fluid close to the fin and that in the middle of the channel. Two kinds of vortex generators are considered: a delta winglet pair and a rectangular winglet pair. For both, good agreement is obtained between numerical results and data in the literature. The vortex generator concept is found to be very efficient in terms of heat-transfer enhancement and macro-mixing. Nevertheless, the micro-mixing level is poor due to strong inhomogeneities: the vortex generator must be used as a heat-transfer enhancement device or as a static mixer for macro- and meso-mixing.Copyright © 2003 by ASME


The current state of the beef cattle-breeding industry and the perspectives of its further development with an allowance for the state support are analysed.


In this research, the use of ICTs in India by librarians, particularly in the use of mobile phones, was the focus of this study. To gather the required data for the research, surveys were performed and this approach was implemented. The questionnaire was presented to eight librarians from eight teacher college libraries in the subject of study who responded to it, and the results were used to inform the research. According to the conclusions of the study's materials, ICT use by professional librarians in India is still a relatively recent phenomena, and as a result, it is still in its early phases. The study showed that while libraries utilise information and communications technology (ICT) to deliver some services, these services are insufficient in part as a result of challenges such as a lack of money, a scarcity of trained personnel, and a lack of managerial support. According to the findings of this study, college librarians should get training in information and communications technology literacy since ICT is a dynamic, continuously practising, and training environment that they should take advantage of, as demonstrated by the results of the study. It was proposed that students have access to contemporary ICT instruments, such PCs, printers and scanners, to help them with their home maintenance tasks in order to enhance the administration of educational institutions. The recommendation was also made that libraries should get sufficient help in this respect. The research also advised that college bibliographers participate in attachment programmes with the help of students at the major university libraries to understand the finest practises of modern librarians.


AbstractSeveral studies on sustainable technologies for the built environment (e.g., green roofs, green walls, etc.) have been carried out. Many of these focus on the technical performance of such technologies. Nonetheless, it also becomes necessary to examine how the public perceives such technologies. This understanding is clearly important to support their widespread use. More specifically, such perception can be incorporated into product design to increase people's acceptance. The contribution of this paper is twofold. First, it presents results of a survey examining the perception of people from a small city in the Southern region of Brazil (Feliz, RS) regarding three sustainable technologies: green roofs, green walls, and composting (or dry) toilets. Second, it proposes a set of preliminary design guidelines to improve acceptance of more sustainable technologies based on people's perception: (1) make the technology look good; (2) make visible the benefits provided by the technology; and (3) design t...


In this work, we have tried to bring out the concentrations of air pollutants over India during September to December 2015. Black carbon (BC) and organic carbon (OC) concentrations can impact the atmosphere on long-term. The transportation of these aerosols can change the weather of particular areas. Studying these two parameters can help us to take some measures in advance. The air pollution over Indian cities has been increasing at high rate which leads to adverse effects in future. This is mainly due to the increase in population and growth in economic activity. The present study is carried on Indian region. The study mainly concentrates daily variation over entire Indian region. We have studied parameters like sulphur dioxide (SO2), particulate matter (PM2.5), BC and OC.


Abstract This paper reports an international project which took place at Nicolaus Copernicus University, where students and teachers from four European universities met for a two-week summer school. The main objective was to develop intercultural competence of teachers of English as a foreign language and their ability to demonstrate this skill during an English lesson. The paper depicts the tools implemented in the project and shows how they affected the learning outcomes by presenting the students' and teachers' perspectives.


(57) Abstract: The invention AUR-1 and / or AUR-2 polypeptides, nucleic acids encoding such polypeptides, cells containing such nucleic acids, tissues and animals, such antibodies to the polypeptides, concerns a method related to all such assays utilizing polypeptides, and the foregoing. Treatment for AUR-1 and / or AUR-2 polypeptide and AUR-1 and / or characterized by abnormal interaction between AUR-2 binding partner AUR-1 and / or AUR-2 associated disease or condition , diagnostic and screening methods are provided.


Haebomyeon Gwangam-ri, Hampyeong, Cheonnam is the setting and burial grounds of causalities from the warring factions that took place during the 6.25 war, particularly on Februcuy 20, 1951(Luna New Year full moon) when the armed forces sought to suppress partisans and sympathizer with the refugees of operations as if they were associated with an even. According to the words of one military record, the armed forces military actions around Bulgapsan totaled more than any other battle with about 350 operations; and 1005 were killed during the operations, a historical record. However, public interest groups have argued and filed for further investigation into the civilian casualties, steadily focusing on families and civic groups and raising the need to identify the actual significance and substance of the case. Conducted in 2009, the effort to excavate the remains of the civilian of Hampyeong Bulgapsan area was carried out under the campaign "Civilian victims of the postwar Korea after war-related civilian victim group". Excavation at Bulgapsan Gwangam-ri area home village (locality 1), the interviewees stated that fewer than the number of civilians appear to be victimized. From all the 159 remains, 29 were female and 35 people under 19 years of age. While more than 1,000 civilians were said to be slaughtered at Bulgapsan, the families claim it was mostly at the expense of innocent civilians. Anthropological survey of deposits in the region shows remains of large number of women and children, suggesting the operation conducted was similar to military combat. Unlike the civilian victims of complementarity was found. Therefore, the military report said the battle of public funds called for complementary information, etc. Further action should be taken accordingly if this evidence need to be corrected or deleted, and the country's public apology is necessary.


551 Abstract 237 patients with hyperthyroidism age range (between 20->60) years attended to nuclear medicine and radiotherapy hospital in Mosul during the period 2001-2003 treated by radioactive iodine 131and followed for one year shows completely relieve from their symptoms after giving them suitable doses of radioactive iodine 131 .The study sample showed that age group between (40-49) years was more affected than others in a percentage of (28.7%). Also the study discovered that females were more affected than males in a percentage of (62%) and (38%) respectively. Our study showed that the main cause of thyrotoxicosis was diffuse hyperthyroidism (46.4%), and the most appropriate given doses needed was (5-10)mc I131 which was about 37.1%. Finally our study revealed that radioactive iodine 131 therapy for hyperthyroidism was simple, Cheap and non invasive method of treatment . عشملا دويلا ةدامب ةيقردلا ةدغلا طرف جلاع مييقت قارعلا لامش يف


The earthquake rescue warehouse management system (WMS) using the radio frequency identification (RFID) technology is presented. The RFID technology is widely used especially in the supply chain management and warehouse operations. To satisfy the emergency, abrupt, speedy need of material out storage for the earthquake rescue, the RFID labels, automatic directional identification and specific coding are synthetically applied in the warehouse management of China International Search and Rescue Team (CISAR) which let the managers do not sign the materials out storage one by one but only to get the record after the work is finished. With the application, there are benefits such as reduce labor levels, enhances visibility, improves inventory management which make the time can be reduced and the rescue team and equipments will be rush to the disaster area soon.


With the economic and technology development, International Corporation among
countries becomes increasingly popular. All countries become an entire unit, therefore
understanding among different cu ...


Abstract Graphene (GN)-filled polylactic acid (PLA) nanocomposites were prepared through a solution blending method with GN weight percent ranging from 0.5 to 2 wt%. Rheological, melting and crystallization behaviors of the prepared PLA/GN nanocomposites were investigated by means of dynamic rheological measurements and differential scanning calorimetry (DSC). The shear viscosities of the PLA/GN nanocomposites decreased with increasing GN content, which was remarkably different from previous reports on the modifications using traditional nanofillers (e.g., clay, carbon nanotubes, etc.). The nonisothermal melt crystallization kinetic analysis suggested that GN served as a nucleating agent and could considerably promote the PLA's crystallization through heterogeneous nucleation. Our findings suggested that at relatively low cooling rates (ϕ ≤ 10 °C/min) even a small amount of GN promoted the nucleation and considerably increased the crystallization rate. However, the crystallinity began to decrease at higher cooling rates (e.g., ϕ ≥ 20 °C/min), especially when the GN content was high (e.g., 2 wt%), possibly owing to the GN aggregation effect considering PLA is a slowly crystallizing polymer.


Purpose – The purpose of this article is to share some high level findings of a continuous program of research designed to identify critical success factors for important corporate activities such as bidding, building relationships, purchasing and pricing.Design/methodology/approach – Survey participants are ranked in terms of outcomes attained and the activities and approaches of high and low achievers are compared to isolate factors that account for the differences in results secured.Findings – The investigation reveals that critical success factors can be determined and built into processes and support tools. Most of the identified critical success factors are attitudinal and behavioral.Research limitations/implications – The implications of the research are that average performers can be enabled to emulate and adopt the approaches of high performers. However, many training and development professionals oppose rather than support related developments. Future research might usefully examine their reserv...


Piperine is a major component of black pepper, Piper nigrum Linn, used widely in traditional medicine. In this study, we examined whether piperine could protect HEI‐OC1 cells against cisplatin‐induced apoptosis through the induction of heme oxygenase‐1 (HO‐1) expression. Piperine induced the expression of HO‐1 in dose‐ and time‐dependent manner. Piperine also induced ARE‐luciferase and translocated Nrf2 to nucleus. Piperine activated the JNK, ERK, and p38 mitogen‐activated protein kinases (MAPKs) pathways, and the JNK pathway played an important role in piperine‐induced HO‐1 expression. Piperine protected the cells against cisplatin‐induced apoptosis. The protective effect of piperine was abrogated by zinc protoporphyrin IX (ZnPP IX), a HO inhibitor, and antisense oligdeoxynuceotides (ODN) against HO‐1 gene. These results demonstrate that the expression of HO‐1 by piperine is mediated by both JNK pathway and Nrf2, and the expression inhibits cisplatin‐induced apoptosis in HEI‐OC1 cells.


Abstract : This document summarizes studies performed under AFOSR Contract: F49620-91-C-0016. In this study equilibrium and nonequilibrium electron and hole transport in quantum scale structures were studied via solutions to the quantum Liouville equation in the coordinate representation The coordinate representation density matrix solutions are the first to provide the quantum distribution function for electrons and holes in nanoscale devices coupled to model dependent dissipation. Illustrations of the use of the algorithm for quantum and classical devices are presented. A discussion of the quantum hydrodynamic equations is included because of its importance in studying dissipation. A summary of the transient studies and the initiation of two- dimensional studies is also discussed. A considerable number of publications have emerged from this study, all of which are included in this document. Quantum transport, Liouville equation, Resonant tunnelling, Dissipation, Density matrix, Transient.


Motor vehicle traffic deaths for June 2007 declined by 2 percent from June 2006, to a total of 3,840. Figures for traffic deaths for the first 6 months of 2007 totaled 21, 080, showing only a 1.0 percent decrease from the 21,380 deaths recorded for June 2006. There were 1,096,000 disabling injuries for the first six months of 2007, showing a 5 percent decrease from 2006. The cost of motor vehicle collisions for the first 6 months of 2007 fell 1.0 percent from 2006, to a total of close to $113.8 billion. The estimated annual mileage death rate stood at 1.5 deaths per 100 million miles of vehicle travel, which was the same for 2006. Statistics on a statewide basis are also given.