[Objective] To observe the therapeutic effects of acupuncture on cer vical vertigo(type of phlegm and turbid obstruction in the middle-jiao). [Metho ds] Sixty-five patients with established cervical vertigo were randomly divided into acupuncture group treated with "regulating spleen and stomach" and drug gr oup treated with intravenous drip of betahistine hydrochloride injection and ora l Xuanyunting. The main symptoms were assessed after treatment, and the average blood flow velocity of bilateral vertebral and vertebro-basilar arteries was obs erved by transcranial Doppler examination. [Results] Blood flow velocity of th e both arteries increased significantly in these two groups (P0.01) after tre atment;there was significant differences between two groups in the total effecti ve rate and indexes of Transcranial Doppler examination (P0.05). [Conclusion ] Acupuncture therapy of "regulating spleen and stomach" posses a better therap eutic effect on cervical vertigo.


In this paper, we discuss an optimization‐based approach for minimum‐cost seismic retrofitting of hysteretic frames with nonlinear fluid viscous dampers. The proposed approach accounts also for moment‐axial interaction in the structural elements, to consider a more realistic coupling between added dampers and retrofitted structure. The design variables of the problem are the damping coefficients of the dampers. Indirectly, the design involves also the stiffness coefficients of the supporting braces. In the optimization analysis, we minimize a realistic retrofitting cost function with constraints on inter‐story drifts under a suite of ground motion records. The cost function includes costs related to the topological and mechanical properties of the dampers' designs. The structure is modeled with a mixed finite element approach, where the hysteretic behavior is defined at the beams' and columns' cross sections level. We consider damper‐brace elements with a visco‐elastic behavior characterized by the Maxwell model. The dampers' viscous behavior is defined by a fractional power law. Promising results obtained for a two‐story, a nine‐story, and a 20‐story 2‐D frames are presented and discussed.


This paper investigates the validity of the Expectations Hypothesis of the Term Structure (EHTS) employing standard forward-spot regressions which accommodate for the presence of time-varying term premia. The novelty of this paper is that the analysis is conducted by taking advan- tage of the following two properties of the Kalman Filter: first, it makes possible to model time-varying term premia as unobservables, and second it delivers recursive estimations of forward-spot regressions as more data become available. In fact, previous studies have modelled term premia by means of macroeconomic variables. To the extent that term premia are influenced by political and social climates which are difficult to ob- serve, it might be preferable to model them as unobservables, rather than by means of observed variables. Moreover, especially when tested over long periods of data, the EHTS might hold for certain periods while it might not for others. These periodic departures from and reversions to the EHTS cannot be detected by constant parameters models, which there- fore can provide only broad brush evidence. This paper shows that the recursive nature of the Kalman filter can be employed to construct a test for the EHTS which gives more refined evidence. The analysis is carried out focusing on the short-end of the US term structure spectrum.


Background: Androgen deprivation therapy (ADT), used increasingly in the treatment of prostate cancer (PCa), negatively influences glycemic control in diabetes and is associated with an increased risk of diabetes complications where hospitalization commonly ensues. Metformin could decrease the metabolic consequences of ADT and enhance its effect. This study examined the association of metformin use with healthcare resources utilization among diabetic, PCa patients receiving ADT. Methods: Diabetic adults with PCa on ADT in Hong Kong between December 1999 and March 2021 were identified. Patients with < 6 months of concurrent metformin and ADT use were excluded. All included patients were followed up until September 2021. The outcomes were hospital attendances and related costs. Results: In total, 1,284 metformin users and 687 non-users were studied. Over 8,045 person-years, 9,049 accident and emergency (A&E), and 21,262 inpatient attendances, with 11,2781 days of hospitalization were observed. Metformin users


This paper described the design of multiple element of microstrip patch antenna array operating at 2.45GHz for WLAN and 5.85GHz for WiMAX applications. The design and development also focus on different type antenna such as rectangular and circular patch antennas. Microstrip antennas have the attractive features of low profile and light weight. However the antennas may be too large for practical applications at the lower microwave frequency range and may offer only a few percentage of bandwidth. Computer Simulation Technology (CST) Microwave Studio is used as an effective tool for 3D electromagnetic simulation of high frequency components. A parallel or corporate feed configuration is used to build up the arrays. In parallel feed, the patch elements were fed in parallel with the transmission lines. The transmission lines are divided into two branches according to the number of patch elements. The objective of this project is to develop the antenna that has high gain, directivity and efficiency. Each component of the antenna system is optimized to get the best results. Many factors are considered such as operating frequencies, bandwidth requirements and directivity, all of which affect its efficiency. The analysis on performance will be based on the obtained result especially in radiation pattern, bandwidth and return loss.


We consider an optimal control problem for systems governed by semilinear parabolic partial differential equations with control and state constraints, without any convexity assumptions. A dis crete optimization method is proposed to solve this problem in its relaxed form which combines a. penalized Armijo type method with a. finite element discretization and constructs sequences of discrete Gamkrelidze relaxed controls. Under appropriate assumptions, we prove that accumulation points of these sequences satisfy the relaxed Pontrya.gin necessary conditions for optimality. Moreover, we show that the Ga.mkrelidze controls thus generated can be replaced by simulating piecewise constant classical controls.


In this paper,four mountains in the interior of the Tibetan Plateau were researched with geomorphological methods.Among the four mountains,those with ridges from south to north have glaciers well developed on the east slopes,and those with ridges from west to east have glaciers well developed on the south slopes.Furthermore,glaciers with south and east aspects occupy much more area.Along the latitudinal direction,altitude of snowline is almost the same in the west of 88° E,but decreases sharply from west to east in the east of 88° E.Along the longitudinal direction,altitude of snowline first increases and then decreases from south to north.All the information indicates that moisture feeding the glaciers in the east of Qangtang Plateau comes from the southeast by the Indian monsoon.


With the second longest coastline in the world (after Canada), Indonesia has a big challenge in managing its coastal zone. Ecologically, Indonesia's coastal zone is rich with fascinating biodiversity; socioeconomically, it has played a long-time role as a sustainable source for food, as well as various development programs in Indonesia, such as interisland connectivity, shipping, fisheries, and logistics industries. The integrated coastal zone management (ICZM) concept is considered to be appropriate approach to deal with multi-stakeholders and multi-decision makers complexity in the coastal zone. In this paper, a decision support system (DSS) is developed based on ICZM by integrating numerical modelling and multi-parallel computing. This application system can be used as an interactive tool for managing the coastal area in Indonesia from various point of view, among other policymakers, industries, and coastal planners. The impacts after implementation of a scenario can be seen directly in the system to represent both the benefits and shortcomings. A test case is carried out in the Northern Jakarta coastal area. The system merits are highlighted in delivering direct effects after artificial islands instalment in the domain. DSS-ICZM development is intended to help policymakers in Indonesia improve the quality of their decisions and improve transparency for broad stakeholders.


Liu et al. set out to establish whether progressive loss of the retinal nerve fiber layer (RNFL) occurs in the fellow eye of patients who have unilateral glaucoma. This prospective longitudinal, observational cohort study found that a substantial proportion of fellow eyes demonstrated a significant decline in RNFL thickness over time. The study included 173 patients (346 eyes)—118 eyes with glaucoma and 228 eyes with suspected glaucoma—who were followed for an average of 3.5 ± 0.7 years. All study participants underwent standard automated perimetry (SAP) and spectraldomain optical coherence tomography (SD-OCT) in both eyes at 6-month intervals. Eyes were determined to be progressing by conventional methods: either masked grading of optic disc stereophotographs or SAP Guided Progression Analysis (GPA; Carl Zeiss Meditec). Thirty-nine participants showed evidence of unilateral progression by the conventional methods of GPA, disc photographs, or both during the follow-up period. In these patients, the mean ± standard error rate of RNFL loss in the progressing eye was –0.89 ± 0.22 μm/year (p < .001), and the fellow eye also showed significant RNFL loss (–1.00 ± 0.20 μm/year; p < .001). The remaining 134 participants did not show progression by conventional methods in either eye; however, RNFL thickness declined in these eyes as well (–0.71 ± 0.09 μm/year; p <.001). The authors concluded that loss of RNFL thickness occurs in a significant number of eyes that do not show progression when measured by conventional methods. Further, because glaucomatous damage is irreversible, they recommend identification of progression at an early stage, before it can be seen on stereo disc photography or SAP.


This study presents a complete wave-to-wire model in which a novel wave energy converter control approach based on adaptive vector control is introduced. The proposed control for maximum power absorption of the primary resource is included, as well as the grid interconnection topology and required controllers, needed for processing the power over the entire wave energy conversion chain. Thanks to the adaptive performance of the proposed controller, maximum energy extraction can be instantaneously achieved regardless of the current irregular wave characteristics of the resource. Finally, the proposed electrical configuration arises as a suitable grid interconnection solution, as it not only provides maximum power supply from the wave energy resource, but it also contributes towards further reducing its output power oscillations.


Abstract This article recommends social science research-based recommendations for improving first responder safety and occupational health by assessing cooperative intelligent transport systems (C-ITS) for use by emergency services and law enforcement. This involves vehicles using digital technologies to inform each other or via objects such as roadworks signs about traffic situations and dangerous circumstances. The application of information and communication technologies to the road transport sector and its interfaces with other modes of transport shall make a significant contribution to improving environmental performance, efficiency, including energy efficiency, safety, and security of road transport. This article investigates which social science aspects must be considered when implementing C-ITS, so that emergency vehicles such as ambulances can be given automated priority. Since emergency vehicles can communicate with traffic signal systems or other vehicles, safety requirements play a particularly important role. This leads to the question of which challenges subjective safety and technology perceptions regarding first responders are essential for the introduction of C-ITS for first responder organizations and which factors can lead to rejection.


Today, in response to the demands of managed care, licensed health providers have become increasingly dependent upon managed care contracts with managed care organizations to market their services. These contracts, while contributing to the provider's patient base, introduce new legal, contractual, and financial risks that the provider must consider. This article reviews important contract provisions that must be clarified, revised, and finalized to the satisfaction of the provider and his or her legal counsel, before "signing on the dotted line." Susan E. Ziel, R.N., M.P.H., J.D., practices with the law firm of Nelson Mullins Riley & Scarborough, LLP in Columbia, South Carolina. Ms. Ziel is a health law attorney with five years of experience in serving health care systems and providers in matters involving fraud and abuse, managed care, credentialing, reimbursement, and other operational issues. Ms. Ziel is also a registered nurse with over 15 years of experience in critical care nursing, health care administration and consulting. Ms. Ziel is currently a member of numerous health care and health law organizations, including the American Nurses Association, the National Health Lawyers Association, The American Academy of Healthcare Attorneys, The American Association of Nurse Attorneys, and the editorial board of the Journal of Nursing Law.


At the archaeological excavations carried out during 1998 in Santa Marina street, near the internal face of the Late Roman wall of Leon, an important building of the legio VII gemina fortress was discovered. It was identified as a magazine with a central courtyard, erected by this legionary unit at the end of the 1st c. AD. Inside one of the constructions a fragment of a manica or a laminated arm protector was found.
This element consists of 11 overlapping plates of different sizes, four of them trapezoid and seven rectangular and of greater size. Some fragments were preserved, which could have been leather. This ensemble became deformed by crushing. This protector was abandoned around the last quarter of the 3rd c. AD in a room which was possibly a storage area and was crushed by the collapse of the roof of the building.


Eight indices at the end of the volume—for both volumes are printed with consecutive pagination, vol. ii. beginning with p. 502—enhance the practical utility of the book. These indices are (a) of Hebrew titles of books; (b) of Arabic titles; (c) of Hebrew technical terms; (d) of Arabic technical terms; (e) of authors and subjects arranged alphabetically ; (/) a chronological table of the translators; (g) a list of anonymous translations; and (h) last, not least, an index of all the MSS. used by the author, and where they are to be found in his book. It has received one of the prizes of the French Academie des Inscriptions et Belles Lettres, and the learned world will concur in awarding to the author the praise that is due to painstaking, unselfish, and devoted labour; to profound learning and scholarly treatment of a subject, hitherto scarcely touched upon, and now exhaustively dealt with.


Richard Bensel's comment on my article "Populism, Paranoia, and the Politics of Free Silver" is, like all of his writing, thoughtful, careful, detailed, and well written. However, I find that I disagree with a number of Bensel's points. In this response I try to clarify areas of disagreement and point to several cases where I believe my argument has been slightly misconstrued, which is understandable given the length and complexity of the paper.


Hematoma enlargement (HE) is associated with clinical outcomes after supratentorial intracerebral hemorrhage (ICH). This study evaluates whether HE characteristics and association with functional outcome differ in deep versus lobar ICH.


Several studies have suggested that GnRH is instrumental in triggering the LH surge. The present studies were performed to evaluate the effect of GnRH antagonist administration in women after the beginning of the LH surge.


Catalytic taken by the method of thermal cracking of heavy hydrocarbons to ethylene and propylene, is the preheating of the heavy hydrocarbon oil in a riser or downflow transfer line reactor, in the presence of steam at a high temperature and a molecular sieve containing pillared clay catalyst and / or a phosphorus and aluminum or magnesium or calcium modified high silica pentasil zeolite, the reaction temperature is 650 ~ 750 ℃, reaction pressure 1.5 ~ 4 × 10


Quality of Sikhe, the Korean conventional rice beverage depended on the characteristics of saccharifying activities of various amylases, intrinsic flavour, budding rate and so on. To improve the quality of Sikhe, characteristics of malt produced with wheat, covered barley and naked barley were evalu...


In the Russian system of higher education and science between two large federal programs Project 5-100 and PRIORITY 2030 the issue of developing entrepreneurial activity of universities becomes more essential. At the same time, most of the existing studies of the factors of universities' own incomes and related characteristics were made on foreign data, and their results are not always applicable to Russian reality due to the historical and structural features of the higher education system and science. In 20192021, the authors of this article contributed to this gap by conducting a number of studies on the data of the Monitoring of the effectiveness of the activities of educational institutions of higher education. This article is aimed at combining the results of both these studies and other empirical studies of the factors of the economic performance of Russian universities. The main result of the article is a summary table that highlights these factors, associated indicators and the direction of influence. The article can be useful for managers in the field of higher education and researchers of university economics.


This article presents an overview of the architectural and algorithmic features of TEAMS-RT, a real-time fault-isolation tool in Qualtech Systems' suite of software tools for integrated diagnostics, system and maintenance. Following an introduction to the fault-modeling methodology underlying the algorithms, the approach used by TEAMS-RT to isolate faults based on received test results is presented. An overview of a data-preprocessing front-end to TEAMS-RT that computes test-results is also provided; this module makes the tool usable in a wide range of application scenarios, provided a library of suitable fault-detection modules is available. A prototype library of signal-processing routines has been implemented to support detection of faults in aircraft flight systems. Finally, we present issues and results pertaining to a distributed architecture of TEAMS-RT for deployment in large systems.


Doescher, Paul S., HSRC., December, 1977. Forestry. Evaliiatlon of Early and Late Successional Native Plant Species for Revegetatlng Coal Mine Spoils In the Fort Union Basin. Director: Lee E. Eddleman The objectives of this research were 1) to determine germina tion and Initial root growth response to moisture stress and strip mine spoils, 2) to develop methodology for measuring that response, and 3) to test the hypothesis that early and mld-successlonal or sta ble climax species need to be Included in seed mixtures for strip mine revegetatlon. Seeds of Agropyron amithii, Agropyron spioatwij Brams teatomMa Etymus canadensis, Koetevux oTistata, Sitanion hystrix, Linum Tigidm, and Fetalostemon oandidm were germinated In 0, -3, -6, -9, and -12 bar osmotic solutions depressed by PEG 6000. Results of germina tion trials indicated that in general an Increased water stress de creases germination amount and slows germination rate. Also, for ijfs's below -6 bars, species response to water stress was more clearly defined. Agropyron spiaatum, Sitanion hystrixj Bromus teotarvm, Koeteria oristata, and Fetdlostemon aandiSm exhibited rela tively strong germination at low potentials but only Agropyron spioainm, Sitanion hystrix, Bromus teatorunig and Koeten â cristata showed signs of seedling growth and survival. Research examining root growth rate and shoot blomass produc tion for plants grown in strip mine spoil and native soil were eval uated for Agropyron snrCtkCij Agropyron spioatunij Etymus canadensis, Sitanion hystrix, Dinum rigidiotij and Petatostemon oandidum. Agro pyron smithii was the only species to exhibit a significant decline in root growth rate through spoils material. No significant dif ferences were found In shoot blomass production between native soil and strip mine spoil. Because available moisture is a primary limiting factor in the seml-arld climate of southeastern Montana, the ability of a species to germinate and survive under the Influences of moisture stress is a demonstrated ecologlc advantage. Agropyron spicatum, Sitanion hystriXf Koeteria cyrlstata, and Bromus tectorum would apparently do well on saline spoils and under conditions of periodic soil drought. However, on the basis of desirable economic and ecologlc properties, Agropyron spicatum, Sitanion hystrix, and Koeleria cristata were recommended for the revegetatlon of strip mined lands.


China Construction Bank is one of four majors which are nationalized banks with a long history. For research and prevent uncertain China crited risk,the commercial banks face general branching the economic developing,and then improve the risk early warning system of bank credit. Through on study current system,we established new credit risk model designed the new standards of finance indicators combined with the work experience,and tested to obtain the theoretical inspection of success.


This book provides a practical approach to model systems. This approach is based on the modeling of many system and context aspects in small and simple models. These small models have to be used together to support the creation process of systems. It extends the notion of threads of reasoning and build on methods such as key driver graphs. A fast iteration over top-down models and bottom-up models is promoted.


Based on traditional technology of rice wine production,a new technology of decreasing the alcohol content in rice wine was developed in this paper including immobilization technology,low temperature evaporation,freezing,membrane filtration and separation technology.By applying these techniques,the quality of rice wine was greatly improved and the product was characterized by representative style of yellow color,clear and fragrance.


A single-step in-flight microplasma synthesis of alkyl-terminated blue-luminescent silicon nanocrystals (Si-NCs) is presented. A mixture of silicon tetrachloride and methane is activated in a medium-pressure (20 kPa), miniaturized (200 μl) non-thermal plasma reactor. Hydrogen species derived from methane abstract chlorine from SiCln efficiently, while partially decomposed methane fragments terminate Si-NC surface. A miniaturized reactor works as short-residence-time reactor which suppresses excess crystal growth, leading to monodispersed 2 nm crystalline particles. Although gas temperature of the microplasma is elevated up to 1000 K, crystalline nanoparticles are obtainable at room temperature in the sense that no heating devise or high temperature post-annealing is required. As-produced Si-NCs are fully passivated by short chain alkyl groups: Si-NCs are readily suspended into toluene and glow bright blue-photoluminescence (440 nm) upon irradiating UV light source. Indirect electron-hole recombination seems to dominate luminescence mechanism in the present Si-NCs.


The authors present a highly efficient program method for high-speed, low-voltage, and multi-bit/cell operation in the conventional silicon/oxide/nitride/oxide/silicon structure. This method uses a forward bias for collecting the electrons into the substrate whilst both substrate and drain biases are used for injecting the electrons into the nitride layer. With an aid of the substrate bias for electron injection, we obtained a program time as short as 600 ns and an ultralow-voltage operation with a drain voltage of 2 V and a substrate voltage of -3 V. In addition, a localized charge-injection near the junction edge was confirmed with a threshold voltage difference of 1 V between the forward and reverse read.


Presents key social science findings from three National Fire Plan-sponsored research projects. Articles highlight information of likely interest to individuals working to decrease wildfire hazards on both private and public lands. Three general topic areas are addressed: (1) public views and acceptance of fuels management, (2) working with homeowners and communities, and (3) tools that can help us understand social issues.


A thin film transistor and a manufacturing method thereof are provided to enhance reliability and a yield and to prevent generation of cracks by improving a structure thereof. A protective layer(110) is positioned on a substrate(100) and includes a compressive material. A source electrode(120a) and a drain electrode(120b) are positioned apart from each other on the protective layer. A semiconductor layer(130) is positioned between the source electrode and the drain electrode to be connected electrically to the source and drain electrodes. A gate insulating layer(140) is positioned on the protective layer including the source electrode, the drain electrode, and the semiconductor layer and includes an extensible material. A gate electrode(150) is positioned on the gate insulating layer overlapped with a region on which the semiconductor layer is positioned.


Digital computing is based on deterministic bits with two values, 0 and 1. On the other hand, quantum computing is based on qubits which are delicate superpositions of 0 and 1. This talk draws attention to something in-between namely, p-bits which are robust classical entities fluctuating between 0 and 1 [1]. Feynman [2] used the concept of a probabilistic computer as a counterpoint to the quantum computer, noting that " .. the only difference between a probabilistic classical world and the equations of the quantum world is that .. the probabilities would have to go negative .. " The awesome power of quantum computing comes from exploiting these negative (more generally complex) probabilities, which in turn requires stringent experimental conditions to protect the phase. A probabilistic computer by contrast can be built with existing technology to operate at room temperature as we have demonstrated experimentally [3]. They lack the magic of complex probabilities but can function as hardware accelerators for many applications that use stochastic algorithms [4]. [1] K.Camsari and S.Datta, IEEE Spectrum (2021); [2] R.P. Feynman, Int. J. Theor. Phys. 21, 467 (1982); [3] W.A. Borders et al. Nature 573, 390 (2019); [4] B.M. Sutton et al. IEEE Access 8, 157238 (2020). Bio Supriyo Datta received his PhD from University of Illinois at Urbana-Champaign in 1979 and has been with Purdue University since 1981. The non-equilibrium Green function (NEGF) method pioneered by his group is widely used for the modeling of quantum transport in nanoscale devices. He is also known for innovative theoretical proposals that have inspired new fields of research including spintronics and negative capacitance electronics. https://nanohub.org/groups/supriyodatta P-bit: Between a Bit and a Qubit Wednesday, August 4, 2021, 2:00PM Via Zoom: https://asu.zoom.us/j/89860857827


Aiming at enhancing the disturbance suppression ability of attitude control of quadrotor UAV (Unmanned Aerial Vehicle), design an ADRC(Active Disturbance Rejection Control) based on quadrotor UAV. Different from the traditional trial adjustment of the parameter b0 in ADRC design, it can be derived according to the characteristics of the quadrotor model in this paper. Firstly, a non-linear kinematic model of a quadrotor UAV is established, and then each module of the ADRC is designed and debugged by modules. Finally, the system is simulated and verified. The experimental results show that ADRC has a stronger disturbance suppression capability than PID control, which greatly improves the stability of the system and enhances the drone's flight control ability in complex environments.


It is a problem of both theoretical and realistic significance to evaluate the private entrepreneurs of our country, this paper attempts to establish a synthetic evaluation system that includes 4 first level indexes and some sub indexes to evaluate the private entrepreneurs.


n his book, The Dance of Person and Place, philosopher and scholar Thomas M. Norton-Smith defines a worldordering process as one that creates patterns in sense experience through space and time. He posits two major world-ordering principles within the Native American worldview, relatedness and circularity. In this essay I argue that rhythm and its role in Native life serves as the impetus for both of Norton-Smith's world-ordering principles. I will show how rhythm, as presented initially by Lakota philosopher Robert Bunge, orders not only time but space as well and so can be understood as the logos that underpins the world-ordering principles of relatedness and circularity. The indigenous peoples of North America had and continue to have many diverse cultures that emerged in response to varied social and ecological contexts. For the purposes of this essay I will speak of a "Native" worldview, but it is important to note that this worldview is a construct based on generalities made about a collection of distinct and autonomous nations. These


In a specialist market public information shocks may generate a sequence of transactions at stale prices, as nimble floor traders pick off obsolete limit orders. We design a test for the importance of public information in price formation around this fact. We find that removing all potentially stale limit order trades from the transactions record has no significant effect on a statistic that links price change to transactions. We use the bootstrap to calibrate this result and demonstrate that public information shocks account for a small portion of stock return variances.


aithful production of sound, as originally intended, is achieved with instruments that have not undergone any significant change since their construction. Instruments made of clay or stone meet this requirement of preservation over long periods. The dry climate prevalent on the Peruvian coast has preserved fragile textiles and also musical instruments (found among the contents of graves). Museum and private collections retain such artifacts, and panpipes made by craftsmen of the Nasca culture have been preserved in sufficient numbers for comparative studies. Studies covering Nasca panpipes were reviewed by Stevenson (1968:245-255). The pentatonic scale originally postulated for the Precolumbian period in what today is Peru has recently been questioned. About one-third of the samples covered in two investigations were labeled twins, or pairs, such as those on Moche vase paintings from the North Coast, which frequently show two panpipes linked by a cord. Dawson (1964) demonstrated slip casting to be the technique used by craftsmen of the Paracas and Nasca cultures of the Peruvian South Coast for producing pipes for panpipes. Essentially all the published pitch data pertaining to Nasca panpipes are expressed in Western notation with plus and minus signs to denote deviation from the written pitches. It was intended that the present study would use this information to determine the scale system used for the tuning of these instruments, but this plan was abandoned when results differing from the ones using frequency measurements were arrived at by using Western notation for the instruments to be described below. The purpose of this study is to describe twelve Nasca panpipes, to present tonometric measurements, and to analyze the determined frequency intervals in order to establish the scale system intended for the tuning of these panpipes.


In this paper, an adaptive integrated framework is devised to provide continuous video service from a base station to multiple secondary users over a cognitive radio network. A channel allocation algorithm is introduced to adaptively assign the available channels to the secondary users while taking into considerations their buffer occupancies as well as the maximum available bit budget and the deadlines of the video frames. The proposed scheme aims at improving the video quality by increasing the number of received enhancement layers for each transmitted video frame. This is done by jointly adapting the modulation levels and channel coding while benefiting from frames retransmissions, when possible, to guarantee their successful reception when they can still meet their deadlines. The simulation results show that the proposed scheme reacts to the variations in channel conditions as well the dynamics of the playback buffers at the secondary users' end by representing the transmitted video information at the highest possible bit rates while exploiting the scalability feature of the encoded video frames. This is reflected in the improved perceptual quality as received by the secondary users with uninterrupted playback.


The corrosion types of the cyclic cooling water system of shipping motive force systems were discussed and the inhibitor technology was proposed to prevent the system corrosion.The requirements for suitable inhibitor are analyzed and system tests to evaluate the anti-corrosion effect of the inhibitor are summarised.


Abstract : Results are given for two series of tests of wind fastening knee plates on one of the transport aircraft having varying accrued operating time under operational conditions. Data obtained can be used to estimate wing fatigue life.


In the title molecule, C13H9NO, the fluorene system and the oxime group non-H atoms are essentially coplanar, with a maximum deviation from the fluorene mean plane of 0.079 (2) Å for the oxime O atom. A short intramolecular C—H⋯O generates an S(6) ring. In the crystal, molecules related by a twofold screw axis are connected by O—H⋯N hydrogen bonds, forming [100] chains Within these chains, molecules related by a unit translation along [100] show π–π stacking interactions between their fluorene ring systems with an interplanar distance of 3.347 (2) Å. The dihedral angle between the fluorene units of adjacent molecules along the helix is 88.40 (2)°. There is a short C—H⋯π contact between the fluorene groups belonging to neighbouring chains.


The (core) competency-based education theory presented through the OECD's DeSeCo project and its follow-up project (OECD Education 2030), stems from the motivation to pay appropriate attention to practical knowledge beyond cultivating theoretical knowledge that has been traditionally emphasized. The main theoretical sources constituting the epistemology of competency-based education theory can be presented as follows: analytical philosopher Gilbert Ryle's distinction between 'know-how' and 'know-that', political scientist Michael Oakshott's criticism of technological rationalism and his distinction between the politics of faith and that of skepticism, and physical chemist, historian of science, and philosopher of science Michael Polanyi's concepts of tacit knowledge and personal knowledge. However, discrepancy between what the OECD's competency-based education theory originally intended and its actual realization is first found in the program of the OECD projects itself; and this problem is much more seriously revealed in the process and appearance of introducing and applying competency-based education theory into the Korean higher education system. This self-contradiction that 'betrays' the original theoretical request of competency-based education theory is identified in the following areas: the OECD projects' reduction of competences as 'know-how' to the form of propositional knowledge, in the situation in Korea, in the state's status that claims to be a rule maker, in the future discourse based on simple logic of technological determinism, and in the making of propositions and the quantification of competencies. Such problems are resolved by abolishing measures of forcibly introducing and applying a specific educational discourse by the state, and making the competency-based education theory a subject of free choice through deliberation at individual educational units.


Objective To learn about the current status of the notifiable infectious disease surveillance,reporting and management of Gansu province in 2008 and find the disadvantages and make out the correcting measures,to improve the quality of infectious disease surveillance.Methods Taking 2 cities in Gansu province as the sampling regions by use of the stochastically stratified sampling method,and 28 organizations were selected to be investigated from the following several sites of the epidemic situation net coverage rate,case log and the infectious disease reporting card record and so on.Results The internet-based direct reporting rate of the medical units of the county and above levels in Gansu province reached 98.34% and it was 90.74% in the level of township hospitals,the integrated reporting quality of Pingchuan district was the best among all the seven checked counties/districts.The descending rank of coherence,accuracy,completeness and timeliness of the individual case information reporting was the township level,county level,municipal level and province level.Conclusions The coverage rate of the epidemic situation net and the accuracy and completeness of the statutory infectious diseases reporting in Gansu province need to be further improved,the rate of failing to report should be further reduced.


An original computer-aided analysis package of the Swamy-Thyagarajan wave digital filter structures has been developed, by the authors, on the minicomputer PDP 11/45 GT-44 Graphics System. The package utilizes the chain matrices of the digital two-ports of the Swamy-Thyagarajan wave digital filter structures which are expressed in terms of the coefficient multipliers of the digital two-ports and the Z variable. The elements and values of a doubly terminated LC ladder can be entered on a cathode ray tube display by utilizing the interactive graphics capability of a light pen. The ladder is then transformed into the Swamy-Thyagarajan wave digital filter structures. Port resistances, coefficient multipliers, chain matrices, the coefficients of the digital filter transfer function, transformed lowpass, highpass, bandstop and bandpass filters can be obtained. The package provides numerical values of the amplitude and phase responses, and plots the responses on the cathode ray tube display.


An examination has been made of the carbonyl stretching bands in the infrared spectra of acetophenone derivatives substituted in the aromatic nucleus. The positions, integrated absorption intensities, and widths of the bands have been measured in carbon tetrachloride solution. The variation of these quantities is discussed in relation to the nature and position of the substituent group.


The biosynthesis of lophocerine (1,2,3,4-tetrahydro-1-isobutyl-6-methoxy-2-methylisoquinolin-7-ol) in intact Lophocereus schottii plants has been studied. The C5 unit of the alkaloid probably arises independently from both leucine and mevalonic acid. 3-Methylbut-3-enyl pyrophosphate, 3-methylbutan-1-ol, and 3-methylbutanal have been shown to be intermediates in the biosynthesis.


Jiang Zemin's ideas against corruption is of distinctive characteristics. In the history of our party against corruption, his ideas occupies a very important status. It is of directive significance for our party to carry out work against corruption in the new era. It is an essential part of Jiang's theory on party construction, as a scientific system which inherited Marxism, Lenism, Mao Tsetong thoughts and Deng Xiaoping theory. It is an important achievement in the summary of the experiences of our party in fighting against corruption.


This paper presents the results from the three-dimensional finite element (3D SE) analysis conducted on Aescher tunnel (Zurich, Switzerland) in which the jet grout columns are used as the main excavation support. The first time in the current literature, a realistic 3D SE model was developed and analysed using a representative example of the canopy-type jet grout excavation support applications. The presented models and the analysis results are validated by comparing with that of the measurement results published previously. The variation in the diameter along the length of the column during the application of jet grouting is modeled assuming the rotated sinusoidal function. The variation of ground settlement in the application process is investigated and thus the conclusions are drawn for analysing such a complex tunnelling construction method.


Most of the research studies available to date on communication protocols for Body Area Nanonetworks (BANs) using molecular communication deals with the protocol stack's lower layers (such as physical, MAC layer), even though the upper layers also (such as transport layer, application layer) play a significant role on the overall performance of the network. Besides, the applicability of classical upper layer protocols for molecular communication in BANs have scopes to be investigated in this context. Therefore, we center our study in developing a specialized transport layer protocol with a view to achieving a delicate balance among throughput, delivery ratio, energy consumption, end-to-end delay etc. network-level performance metrics for molecular communication in BANs. To do so, we exploit a notion of conjugate congestion control mechanism from the perspective of both the sender and receiver to attain the desired performance level as well as produce limited complexity and overhead. We evaluate and compare the performance of our proposed protocol with the existing alternatives through rigorous ns-2 simulation. The results demonstrate that compared to the other transport layer protocols, our proposed one provides a better balance among different performance metrics.


At present, Russian society is characterized not so much by democratization as by economic and cultural dissociation. This dissociation complicates the formulation of the tasks of socioeconomic reform. Moreover, the problem is not merely that of dissociation. Society is socially divided, and this division is so profound and serious that a general understanding of today's Russia and where it is going depends on how this division is evaluated.


ABSTRACT We employed flow cytometry to assess plasma membrane viability of sperm cells in farmed giant kokopu Galaxias argenteus, an endemic amphidromous New Zealand fish. Specifically, the variables of fish size (TL mm) and weight (grams) were assessed against sperm viability. We found no significant difference (P < .05) in sperm viability when compared across size and weight distribution of G. argenteus. This study shows that flow cytometry is an effective, accurate and rapid method for analysing sperm viability in G. argenteus.


Motor- Liability Insurance or third-party liability cover is an insurance policy that covers the insured's legal liability for death or disability to a third-party or damage to the third-party property. Evolving automobile sector and the dynamic consumer preferences in the Indian markets call for the need to analyze the existing practices in the Motor-liability insurance in the market and adapt them according to the changing scenario. The article addresses the problems with the existing practices and makes a few suggestions for adapting the liability insurance for the evolving market.


Members of the pulcher–undulatus species group of Hydroporus Clairville (sensu Fall 1923) were rearranged as follows by Wolfe and Matta (1981): (1) H. pulcher LeConte and 12 other species (each with a bifurcate aedeagal apex) were assigned to the subgenus Heterosternuta E. Strand; (2) H. pilatei Fall and H. triangularis Fall were revised and assigned to a new genus, Falloporus; (3) and the remaining approximately 35 species were placed in the subgenus Neoporus Guignot.


Objective To study the expression of fascin, an actin bundling protein associated with cell motility, and the relationship with ER negative breast carcinoma.Methods Comparasion of the expression of fascin, estrogen receptor (ER) and proliferative cell nuclear antigen (PCNA) determined by immunohistological method was made on 84 specimens of primary breast carcinomas. Results The diffuse staining of fascin in cancerous cell cytoplasm was noted. Only 3 of 53 breast carcinomas with ER positive showed fascin positive expression (5.67%); in contrast, 21 of 31 carcinomas with ER-negative showed positive expression(67.7 %) (P 0.001). Whereas fascin expression showed no significant correlation with menopause status, tumor size, histologic grading or lymph node metastasis. However, fascin expression was highly related to the expression of PCNA in cancer cells (P 0.001 ). Conclusions Over expression of fascin could induce decreased intercellular adhesion and increased cell motility, which might be attributed to the molecular modulators of actin dynamics anticipated to the malignant phenotype of cancer cells. Actin function is influenced by action-bundling associated protein such as fascin, in additioin, fascin is mainly presented in highly PCNA-expressed cancer cells, which suggests that such cancer cells are related to those with high proliferative activity, and may be one of the reasons that the patients with ER-negative breast cancer has worse prognosis than those with ER-positive cancer. But the real mechnism and clinical significance of fascin need futher studies.


with 2 deaths, or 20 per cent.; at greater ages 97 vaccinated cases, 16 deaths, or 16.5 per cent.; and 4 unvaccinated cases, 3 deaths, or 75 per cent. These data show the increasing tendency to attack and death in the vaccinated as age advances and the effects of the primary vaccination wear away; while the disproportionate fatality rate in the unvaccinated class is equally striking in the earlier years of life. Looking to the age periods of all cases, we find the per case rates of mortality were as follow: 0 to 10. 10 to 15. 15 to 30. 30 and over. All ages. Vaccinated ... 0.0 ... 4.0 ... 2.3 ... 18.0 ... 6.6 Unvaccinated ... 26.1 ... 0.0 ... 20.0 ... 75.0 ... 26.8 All cases ... 20.0 ... 3.4 ... 3.2 ... 20.4 ... 10.0 The single death in a vaccinated child under '15 years of age is phenomenal in Dr. Davies's experience of 687 cases of the disease, among which 96 were in children under 15 years of age. In one instance he relates that a baby born while its mother was recovering from small-pox did not catch the disease, and was also roof against vaccination. Treating of the data culled from study of invaded houses, Dr. Davies shows that in Bristol vaccination conveyed, when set against non-vaccination, a twenty-three fold immunity from attack and absolute immunity from death as against 11.5 per cent. fatal in the unvaccinated. at ages under 10 years, and a three-fold immunity from attack and a ten-fold immunity from death at ages over 10 years. Of 59 unvaccinated persons found in invaded houses, 23 were vaccinated on or before the fifth day of exposure to infection, and not one took small-pox in any degree; but of 32 persons remaining unvaccinated and exposed to infection, no fewer than 19 (59 per cent.) contracted small-pox. Of 468 persons thus exposed and successfully revaccinated only 8, in whom the disease had already begun to incubate, were attacked by small-pox, all recovering, and only 5 per cent. of other 859 exposed persons once vaccinated were attacked. Of 62 persons on the hospital and ambulance staff, 3 contracted small-pox, namely, 1 primarily vaccinated only, 1 revaccinated fourteen years back, and 1 (fatally) who had been revaccinated twenty years back, the deceased being a hospital laundress who had on previous occurrences of smallpox also washed the clothing of patients without ill-effect. She was accidentally omitted from the list of those set down as requiring vaccination in the present epidemic. There is other matter of interest in the report which, for considerations of space, we are reluctantly compelled to pass over.


There are revealed the mechanism and law of increment of integral impulse in detonation wave initiated under high velocity through an inert screen. Numerical solutions were performed according to problem definition that is impossible to realize in a real experiment. It is shown that an impulse in detonation wave depends on total thickness of a screen and liner by the same law as in case of initiation by direct impact with a liner. Therefore it is possible to name them as dynamical piston (simple or complex).


What is already known about this topic? In recent years, climate change may lead to an increase in cold spells in the middle latitudes, and there is a positive correlation between cold spells and population mortality. What is added by this report? The acute response period and the vulnerable population were identified under the optimal definition of cold spells, and the mortality burden caused by cold spells was estimated. What are the implications for public health practice? This research would provide evidence on the acute mortality effects of cold spells in southern China. Therefore, vulnerable populations, especially the elderly, should take timely measures to reduce the health damage caused by cold spells, especially in the first week after cold waves.


The study aims to determine the effect of continuous run, alternate pace run and fartlek training on the selected physiological variable (Resting Pulse Rate) among the male athletes of Alagappa University affiliated colleges. The research involved a random subject selection of fifty athletes with age ranging from 17–25 years and had five equally divided groups namely experimental groups A, B, C, Dand control group E with 10 athletes each. The groups endured the training activities for twelve weeks with a schedule of thrice a week whereas the control group remained with no activities. The data procured in prior and after the training programme was examined with the application of Analysis of Covariance and the fixation of level of significance at 0.05. Scheffe's test was applied at the significance of 'F' ratio in order to evaluate the differences that occur significantly between the paired means. The study revealed that the selected physiological variable of the combined group with the three endurance trainings outperformed the other groups.


An algorithm for the numerical solution of optimal control problems is developed which is based on a combination of the direct and indirect approaches. The method presented is similar to the indirect approach in that the known and iteratively improved unknown initial values are used in the integration of the system and Euler-Lagrange differential equations. However, instead of matching end conditions, as is done in the classical approach, the performance function is considered to be a function of the unknown initial values and optimized by a gradient technique, as is done in the direct approach. Since only terminal values are stored, the method can be useful in digital or hybrid controllers of limited memory. It is shown that it is sufficient to search for the intersection of a sphere with a line in the initial condition space. As a consequence, the method is not dependent on a good initial estimate of the initial values.


We report the demonstration of single-photon emission from cubic GaN/AlN quantum dots grown by molecular beam epitaxy. We have observed spectrally clean and isolated emission peaks from these quantum dots. Clear single-photon emission was detected by analyzing one such peak at 4 K. The estimated g(2)[0] value is 0.25, which becomes 0.05 when corrected for background and detector dark counts. We have also observed the single-photon nature of the emission up to 100 K (g(2)[0] = 0.47). These results indicate that cubic GaN quantum dots are possible candidates for high-temperature operating UV single-photon sources with the possibility of integration into photonic nanostructures.


With the dramatic development of biotechnique,more and more biologists and breeders value them.This paper summarized the application of molecular marker techniques such as restriction fragment length polymorphism(RFLP),random amplified polymorphic DNA(RAPD),simple sequence repeats(SSR) and amplified fragments length polymorphism(AFLP0) in marker-assisted selection.


Patterns are all about repetition, the repartition of simple forms that unfold into complex, potentially infinite, systems. Generally this requires artists to pursue their chosen pattern independently while their audience fulfils the role of passive observer to their progress. But in the world of street art where the audience is equally empowered to create as it is to observe, some of the most interesting patterns emerge long after the original artist has put down their tools.


Haplotypes defined by rs7041/rs4588 in GC gene modulate 25-hydroxyvitamin D (25(OH)D) and vitamin D-binding protein (DBP) levels. To investigate the distributions of GC polymorphisms, the rs7041 and rs4588 allele and haplotypes frequencies were analyzed in samples from different Eurasian regions. The GC1S haplotype associated with high level of serum 25(OH)D had the maximum frequency in European populations (except Finish population). Such frequency distributions may be a result of adaptation to low solar insolation rate. Besides, there was a strong trend of increasing GC1F haplotype frequency from Europe (10-15%) to Siberia and Easter Asia (40-45%).


Abstract A linear pinch discharge above the Pease-Braginskii current and stabilized by axial shear flow can radiatively collapse to high densities. A thermonuclear detonation wave can then be launched from one end of the discharge channel by ignition with a powerful laser pulse. Axial shear flow stabilization may be realized by injecting a fast moving jet along the pinch discharge channel, possibly in combination with a frozen DT fiber positioned on the pinch axis.


Aim To inquire into the predictive value of serum troponin T(TnT) levels for the therapeutic efficacy in acute myocardial infarction(AMI)treated by thrombolysis.Methods Ninety-two patients with AMI received venously thrombolytic therapy,of whom the infarct related coronary artery(IRA )were reperfused after thrombolysis in 65 cases.The serum TnT levels were detected by using of automatic enzyme-linked immunosorbent assay(ELISA),so as to analyse its characteristics and values for assessing the thrombolytic effects between reperfusion group and noreperfusion's.Results ①The TnT levels initiated rising 4th~8th hour post onset in most of AMI cases,especially earlier for reperfusion group than noreperfusion's(butP0.05).②The time of arriving to first TnT peak from onset was earlier in reperfusion group than noreperfusion's(17. 78±12.49 h vs 28. 59±15.98 h,P0.001):and the levels of first TnT peak was a little higher in the former than latter.③The sensitivity, specificity and accuracy of predicting IRA's reperfusion were55.4%, 85.2%and 64.1%respectively for the time reaching the first TnT peak≤12 h; while 76.9%,77.8%and 77.2%respectively for time reaching the first TnT peak≤16h.It was preferable to the CK-MB≤14 h , which was 61.5%,74.1%and 65.2%respectively.Conclusions TnT level s has certain predictive values for IRA reperfusion in AMI after thrombolysis.The sensitivity is higher for the time reaching the first TnT peak≤16h than for CK-MB≤14h.


Fine roots play a prominent role in forest carbon flux, nutrient and water acquisition; however, information on fine roots remains scarce due to the limitation of measuring methods. In this study, a nested regression method was used to estimate the biomass and surface area of fine roots of individual Larix gmelinii trees that dominate northernmost China. Aboveground traits including leaf biomass, leaf area, stem volume and aboveground biomass were also investigated. In particular, the relationships between leaves and fine roots, in terms of biomass and area, were examined. The results revealed that allometric models of fine roots, total roots, and leaves consistently fit well with Adj. R2 = 0.92–0.97. The root-shoot ratio at the individual tree level was approximately 0.28. There were robust positive linear correlations between absorption (fine root biomass, fine root surface area) and production (leaf biomass, leaf area) (Adj. R2 = 0.95, p < 0.001). In conclusion, the close coupling between fine roots and leaves presented in this study provides support for the theory of functional equilibrium.


The aim of this study was to estimate the effects of the Japanese carbon offsetting system on the optimum forest rotation period in relation to carbon price, timber price and discount rate. The optimum rotation period required to maximize the present value of forestry profits was calculated using the actual forest area formally identified in the Japanese Verified Emissions Reduction (J-VER) system. For calculating the carbon sinks and harvested timber for J-VER accounting, the Local Yield table Construction System (LYCS) and a wood conversion algorithm were used, in which profits derived from carbon were calculated based on the total tree volume. The optimum rotation period and forestry profits were also calculated using a timber-based accounting method where profits derived from both carbon and harvesting timber were calculated according to the timber volume. By comparing these two methodologies we found that the optimum rotation length increases with increasing carbon prices, but decreases with increasing timber prices. Carbon prices had a greater effect on increasing rotation age for the J-VER accounting system. In addition, the difference between the present carbon price and other proposed carbon prices shows that the advantages and disadvantages derived from the carbon market for forestry depend on current stand age; this difference is greater under the J-VER system than the timber-based accounting system. It is important to include the allocation of harvesting area and stand age distribution in the management units for calculating carbon offset credits when trying to optimize medium- to long-term forest management and to avoid reductions in forestry profits under the existing J-VER system.


individual Emperors. The brevity of the final chapter, "The Later Mughals," points to the lack of serious research on the last century and a half of Mughal rule. The overall chapter division echoes the view that the Mughals used architecture as a means of self-representation. The court was the center of all political and cultural developments, and the emperor the tastemaker. The author aims to provide information about building-types, show stylistic development, and provoke research through fresh interpretations. The brief history of the Mughals and the explanation of their kingship ideals and salient administrative features given in the introduction help us to understand why their monuments synthesized Indian, Timurid, and Iranian ideas. Monuments from the early period are few, and the extant ones seemingly emulate the heavy style of the previous Delhi Sultanate. But Koch shows how purely Timurid elements, like the basht behesht plan, char bagh garden, and the arch netting of the transition zones, were incorporated from the beginning. From the reign of Humayun, usually cursorily treated, she brings to our notice a dated pavilion in the fort of Vijayamandir in Bayana (1533-34). A key building in the understanding of later Mughal palace architecture, it illustrates how local trabeate influences were combined with the trabeate porches of Iran and Transoxiana. The real synthesis took place in the reign of Akbar, whose syncretistic cultural ideas and bold military conquests are all reflected in the work he sponsored. Thus the distinctive Mughal architectural style was born. The theme of the interchangeability of funerary and residential architecture is also introduced here. Koch quickly overturns the misconception that the reign of Jahangir was not architecturally significant. She proves it was a period of transition, reflection, and experimentation, with new variations in the types of tombs, nine-fold plans, material, vaults, decoration of surfaces (the Italianate pktra-dura being a significant innovation). Also new is the patronage of women, particularly in the public spheres, proof of their influence. During the "classical" phase of Shah Jahan, a new ideal of symmetry and uniformity of shapes took over. Hierarchical emphasis was given to white marble, baluster columns, and the curved bang/a cornice. These remained influential for the rest of the Mughal period, particularly among provincial rulers, until their spread throughout India in the twentieth century and ultimate export to Britain. With the exception of the Badshahi Mosque in Lahore, Shah Jahan's reign also marks the end of the grand monumental constructions of the Mughals. The book is profusely illustrated with crisp photographs (colored and blackand-white) and plans, many previously unseen. Apart from new material and interpretations, there is a map of sites, a glossary of non-Indian terms, and a detailed bibliography preceded by a short essay that makes this book a must for scholars of Islamic or Indian architecture. Its brevity and price also suggest its usefulness for teaching.


Frequent and ongoing assessment of a hospital's market size, share of market, and share of mind can have significant implications for marketing efforts.


The invention belongs to the technical field of health food, and specifically relates to a health food with dual functions of protecting liver and adjusting blood fat and a preparation method thereof. The health food is prepared from the following raw materials according to a weight ratio: 25-50 parts of Gynostemma pentaphylla, 8-12 parts of Chinese wolfberry, 10-20 parts of mulberry, 10-20 partsof hawthorn, 15-30 parts of kudzu root, 8-20 parts of red date, 8-12 parts of cedrate, 8-20 parts of ginkgo leaf and 5-15 parts of tuckahoe. The raw materials are medicine and food dual-purpose traditional Chinese medicinal materials, and are extracted, spray-dried and added with auxiliary materials allowed by health food law to prepare tea bag, capsules, tablets, granules and medicine tea beverage. According to the invention, the product proportioning and processing process are unique; and animal experiment and human body trial eating experiments verify that the health food has dual health-care functions of auxiliary protection on hepatic injury and adjusting of blood fat.


Purpose – This paper has the purpose of introducing the inaugural issue of the International Journal of Wine Business Research after the re‐launch from the International Journal of Wine Marketing including rationale, scope, goals, and objectives.Design/methodology/approach – The paper provides a rationale for a journal such as IJWBR. It starts by outlining the global wine business as a complex and fruitful field to study, describes some streams of research, and identifies issues for future studies as potential further contributions to this journal.Findings – There is a critical need for an outlet that provides an overview on current issues and topics in the wine business, promotes high quality research on all aspects related to managing wine and related businesses, and is accessible to both academics and the global wine trade.Originality/value – This paper is essential for current and prospective readers of the journal and those who consider submitting to IJWBR.


The factor of safety has been traditionallyused as an indicator to assess the stability of the slope. For slopes, the factor of safety F is defined as the ratio of the actual soil shear strength to the minimum shear strength required to prevent failure. There are many factors that control the factor of safety. This includes thepresence of water; inherent discontinuities F is the factor by which the soil shear strength must be divided to bring the slope to the verge of failure. In this paper, the factor of safety of the slope COP FD at Nchanga mine is calculated using LEM and FEM and the results obtained compared as a check for consistency.


Genetic algorithms (GA) and particle swarm optimization (PSO) technique are the most notorious among the different modern heuristic optimization techniques. These two methods use various strategies and computational matters for finding solution of specific functions. PSO technique is a new method which is used in biological bases. Here we suggest a new mixed (GA/PSO) algorithm, breeding swarms, which combine the strengths of particle swarm optimizing with GAs. This mixed and hybrid algorithm combines the standard speed. And update rules of PSOs with such cases as selection, crossover, and mutation from GAs. In this paper both PSO and GA optimization are employed for finding stable reduced order models of single-inputsingle-output large-scale linear systems. Both the techniques guarantee stability of reduced order model if the original high order model is stable. Method is based on the minimization of the Integral Squared Error (ISE) between the desired response and actual response pertaining to a unit step input.


The purpose of this study was to examine the effects of music intervention programs for children with ADHD in Korea through systematic review and meta-analysis. For this, nine researches of 1,856 articles published from 2000 to 2019 were reviewed which are experimental studies with the control groups in accordance with selection criteria. As the result of systematic review on four criteria, two or more in each of musical activities, intervention goals, and evaluation tools were employed in most of the nine studies, and there were frequently found studies on sociality and attentiveness. As the result of meta-analysis, there were shown that the overall effect scored medium effect size, and attention deficit and sociality marked low, while problem behavior did medium effect size. It is meaningful that this study showed the importance of using standardized evaluation tools in music intervention for children with ADHD, and it could be used as basic data to develop music intervention programs for them,


This study provides a better understanding of the effect of density and thickness on impact strength of laminated floor panel from Kenaf high density fibreboard (KHDF). The objective of this study was therefore to determine the role of density and thickness on the impact strength of laminated floor panel. Laminated floor panels consisted of high density fibreboard (HDF) as core and decorative paper as surface layer and backing. Kenaf bast fibres were used for HDF with three different densities (850, 960 and 1000 kg/m3) with thickness of 8mm and 12mm for each panel. Energy (J) value was evaluated to determine the impact strength of all various floor panels. It was found that thickness has affected statistically on impact strength while there was no significantly difference existed on density of laminated floor panel on impact strength.


It is often argued that countries with more flexible labor markets are better placed in attracting inward investment from multinational firms (MNEs). This is an issue when there is uncertainty in the marketplace and the firm faces some risk of closure of its branch plant. We study the MNE's location choice, explicitly taking into account exit, as well as entry, costs. We show that worker protection, through lay-off rules, deters potential investment in risky industries. Using evidence on MNE investment in Eastern Europe, we find support for our prediction that labor-market flexibility makes a location more attractive to the MNE.


Abstract A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in situ–generated nitrile oxide derivatives. GRAPHICAL ABSTRACT


It analyses the forming system of the landslide of the left bank of Fujiang,it makes calculations of each working condition combination,believes that there is no possibility of entire landslide or deep landslide,puts forward corresponding treating plan and points out that underground-water level is sensitive to the entire stability of landslide.


The present invention relates to a control system for a vibrator system capable of generating and applying a reciprocating force to an object, such as the underlying ground or water. The control system is generally provided with a means for outputting a drive signal having a fundamental frequency to the vibrator system to activate the reciprocating of the base plate of the vibrating system and a means for receiving a vibrator output signal indicative of the force applied to the object. The vibrator output signal includes at least one harmonic frequency signal and is delayed with respect to the phase of the initial drive signal. To increase the signal-to-noise ratio of the vibrator system, the control system includes a harmonic distortion reduction means receiving the vibrator output signal for outputting at least one harmonic drive signal to the vibrator system. The harmonic drive signal has a proper phase, amplitude, polarity, and frequency which are adjusted to minimize at least one of the harmonic frequency signals being produced by the vibrator system.


ionic species in some representative natural waters using the chemical analyses of the water samples and equilibrium constants for the formation of the various ion pairs. The ion pairs that occur at significant levels in natural waters are CaSO40, CaCO30, CaHC03+, MgS04°, MgCO30, and MgHC03+. Concentrations of CaOH+ and MgOH+ are insignificant at the pH levels considered here, and levels of sodium are sufficiently low that one need not consider sodium ion pairs. Theoretical considerations for formation


Halothane (2-bromo-2-chloro-l,l,l-trifluoroethane) is a potent, nonirritating inhalation agent;fi induction is rapid and (on the basis of human experience) without discomfort. The striking absence of salivation makes anesthesia with halothane safer than with ether as a procedure in the laboratory animal, and a drying agent such as atropine may be omitted.? Since its vapors are nonexplosive, it can be safely used in the presence of electronic equipment. A mechanical respirator may also be employed without concern about explosion hazards.


Inroduction. A Framework for Understanding Atypical Reading: Proximal and Distal Causes of Individual Differnces in Reading. Dual-route Model of Reading. Acquired Dyslexia. Learning to Read and its Difficulties. Precocious Reading and Hyperlexia. Commonalities and Conclusions.


Objective To understand the histopathological features of prostatitis and benign prostat-ic hyperplasia (BPH) in the population of young men. Methods Complete prostate specimens were obtained at autopsy from 140 organ donors ( aged 20 - 35years) who died of non-prostatic diseases. Tissues from the transition zone and the peripheral zone of each prostate were taken for routine pathological examination. Results Of 140 prostate specimens,46 (32.9% ) presented pathological changes of chronic prostatitis, including 42 cases of focal mild stromal inflammation,3 cases of focal mild stromal and periglandular inflammation and 1 case of focal mild perglanduar inflammation;74 (52.9% ) presented pathological changes of BPH. Conclusions The prevalence rates of chronic prostatitis and BPH are both high in the population of young men. Focal mild stromal inflammation is the commonest pathologic type of chronic prostatitis. Compared with documented data,the age of BPH prevalence appears to be younger than it used to be.


Abstract : The question whether the researcher concerned with crisis is able to contribute meaningful knowledge to practical concerns is discussed. Experimental simulation as a potential solution to this problem is considered. It is proposed that the experimental simulation is a compromise technique which however does permit to gain practical knowledge for the solving of social problems, and in addition can help to clarify theoretical issues. The Tactical and Negotiations Game Simulation is considered as an example of an experimental simulation technique specifically designed to obtain data on crisis induced stress.


This paper is concerned with the conceptual basis of multi-agent based formalization of the process of electric power distribution system design. A choice of a multi-agent software architecture is made, the interface protocols and approaches to the coordination of intellectual agents are described. Based on the ontological approach, a multi-aspect information model of electric power distribution systems has been formed. The program implementation of iCAD software for electric power distribution systems has been performed.


This study aims to identify and analyze how the Total Asset Turnover (TATO), Return on Assets (ROA), and Return on Equity (ROE) simultaneously or partial effect on stock return in the Coal Mining industry listed on Stock Exchanges in Indonesia. The data used in this study are panel data, which are a combination of cross section data and time series data taken from 10 companies is research samples during 2010-2011 the four years period from the data collection method is documentation. The analysis technique used is the multiple linear regression. The Results showed that simultaneously Total Asset Turnover, Return on Assets, and Return on Equity, significantly affect the Stock Return. Partially, only Total Asset Turnover affects the Stock Return.
Keywords: Total Asset Turnover, Return on Assets , Return on Equity and Stock Return


. The Median tribes and the Media are mentioned in sources from the last third of the 9 th century BC. At the end of 7 th – the beginning of the 6 th century BC a vast Median empire developed that promoted the spread of the Median language belonging to the northwestern group of Iranian languages. Finally, the Median language, apparently, formed in the Media-Atropatene. Written monuments in the Median language were not found. Separate Median words – mainly proper names, tribal names and toponyms have been preserved in Assyrian, Babylonian and Greek sources, as well as in Old Persian inscriptions. Middle Median (Atropatene) language did not disappear with the inclusion of Atropatene (Adurbadagan) in the Sassanian state, and then the Arab Caliphate. Arabic authors of 9 th –12 th centuries inform about the language Āδ ar ī (Azeri) spread on the territory of Southern Azerbaijan. A lexical-etymological and grammatical analysis of the surviving Azeri material indicates that it belongs to the northwestern group of Iranian languages. The Azeri language has survived to the present day in the form of relict northwestern Iranian dialects – Harzani, Khalkhali, Karingani, etc. The article proposes a conditional periodization of the Median language 1. Old Median language epoch – from the last third of the 9 th century BC to the 320s BC; 2. Middle Median (Atropatene) language epoch – from the 320s BC to the 12 th century AD; 3. New Median language epoch – from the 12 th century until nowadays. The following are some of the etymologies of the Old Median names that are clearly marked in the multilingual and multi-temporal sources as Medians.


Kreitmair (2019) paints a picture of a consumer wearables utopia, one in which all consumer technology contributes in some way to "human flourishing." In this Eden of ethical technology, my Inbox would be limited to ten messages a day (automatically filtering out any distractions), my Twitter feed would not display stressful news, and iPhones would automatically limit speaker volume in public places. Indeed, in Kreitmair's view, all consumer products ought to contribute to "human flourishing," or at the very least not hamper it. This is a lofty ideal, and I admire Kreitmair for staking out such a bold claim. However, the dreary reality is that we live in a capitalist society, where companies that manufacture consumer products are motivated by profit, not goodness. Thus, approaching the real-world problem of direct-to-consumer (DTC) neurotechnology from the starting point of a philosophical ideal may be less productive than approaching it from a grounded understanding of the policy issues, the consumer neurotechnology landscape, and the science. In this regard, Kreitmair has an occasional tendency to overstate the state of the science, often taking companies' marketing claims at face value. Just because companies claim that their products can detect emotions, fly drones, or translate thoughts into speech does not mean that their products can do these things. Similarly, there is no data—as of yet—collected by DTC technologies that is "as sensitive as protected medical information." In fact, as a colleague and I recently argued, it is unlikely that the basic monitoring claims of consumer EEG companies hold much water (Wexler and Thibault 2018). Kreitmair is rightly critical, later in the paper, of companies' wellness and behavioral claims. Kreitmair takes an expansive view of what constitutes a DTC neurotechnology, including products like virtual reality systems, heart rate monitors, and smartphones within the definition. In Kreitmair's reading, the Hexoskin wearable device is a DTC neurotechnology, because it measures heart rate variability which can be taken as a proxy for stress levels which can therefore be viewed as a device that monitors psychological function. With this blanket definition, almost any kind of physiological monitoring device can be taken as a proxy for any kind of psychological function. Thus, rather than wondering what Kreitmair considers to be DTC neurotechnology, I wondered the opposite: what technologies does Kreitmair not consider to be DTC neurotechnologies? Luckily the question is moot, as the definition appears to have little impact on the remainder of the paper: in the seven dimensions outlined, there is little differentiation regarding how each might apply to specific subtypes of neurotechnologies—or whether these dimensions would be applicable to consumer products writ large. It seems that safety, transparency (i.e., truthful claims), privacy, and adequate oversight would apply broadly to any kind of consumer product. Just distribution is relevant to the broad class of technologies that


The Scarlet Letter, Hawthorne's first novel, is known as a self-reflective work of his creativity and life. Hawthorne is a novelist who wants to...


In many cancers mutations in the Ras protein lead to cancer growth and metastasis. In a mutated form, Ras allows cells to avoid a normally programed death called apoptosis. Ras is a GTP‐binding protein and attaches to the cell membrane through a prenylated tail. When attached, it will activate and signal for the promotion of cell survival. The prenylated tail and membrane insertion will keep Ras in its activated state. Typical antineoplastic agents are highly toxic therapies, but by using them in combination with alternative therapies such as lovastatin, proliferating cells may be held in check with reduced side effects. The purpose of these experiments was to examine Ras prenylation and activation in a melanoma cell line, following treatment with a combination of lovastatin and cisplatin. Flow cytometry using annexin‐V apoptosis assay was performed to determine drug toxicities for each drug and in combination. Melanoma cells were treated for 48 with 10 uM lovastatin, then 1.5 ug/ml cisplatin was added for an additional 24 hr. Membrane localization of Ras was determined using immunohistochemistry followed by analysis with ImageJ software. The results show that Ras localization to the membrane in cells undergoing the combined treatment was reduced 4‐fold relative to cisplatin alone (p<0.05). These results indicate that statin therapy combined with traditional cancer drugs such as cisplatin may be more effective at slowing cancer growth with lower toxicities, than with cisplatin alone.


Biomphalaria tenagophila snails placed in a Y-shaped aquarium were studied in terms of their behavorial response to light. Albino populations from Joinvile (State of Santa Catarina, Brazil) and melanic populations from Sao Jose dos Campos (State of Sao Paulo) were used. Snail behavior was measured by the distance (cm) covered per hour and location of the animal in the aquarium. Data obtained for animals with a small shell diameter were compared to those obtained for animals with a large shell diameter studied both as groups and separately. All samples studied were attracted to light, but differences were observed in time os aproximation to the stimulus, which varied with shell diameter and social condition of the animal. The results were compared to those obtained for B. glabrata and B. straminea in previous studies under similar conditions, and discussed in terms of the resnpondes to light by the parasite Schistosoma mansoni.


We analyse the fifth rapidly oscillating Ap (roAp) star reported in the Kepler field, KIC 7582608, discovered with the SuperWASP (Wide Angle Search for Planets) project. The object shows a high-frequency pulsation at 181.7324 d −1 (P = 7.9 min) with an amplitude of1.45mmag,andlow-frequencyrotationalmodulationcorrespondingtoaperiodof20.4339d with an amplitude of 7.64 mmag. Spectral analysis confirms the Ap nature of the target, with characteristic lines of Eu II ,N dIII and Pr III present. The spectra are not greatly affected by broadening, which is consistent with the long rotational period found from photometry. From our spectral observations we derive a lower limit on the mean magnetic field modulus of �B �= 3.05 ± 0.23 kG. Long cadence Kepler observations show a frequency quintuplet split by the rotational period of the star, typical for an oblique pulsator. We suggest the star is a quadrupole pulsator with a geometry such that i ∼ 66 ◦ and β ∼ 33 ◦ . We detect frequency variations of the pulsation in both the WASP and Kepler data sets on many time-scales. Linear, non-adiabatic stability modelling allows us to constrain a region on the Hertzsprung–Russell diagram where the pulsations are unstable, an area consistent with observations.


An introduction to the Spring 2012 (Volume 10, Number 1) issue of The Review of Faith & International Affairs, a special issue on the theme, "Religion and African American Leadership in Global Volunteerism." Both the Peace Corps and Operation Crossroads Africa (OCA) recently celebrated 50th anniversaries, and this theme issue explores how these organizations formalized models of global service and citizen diplomacy that have significantly advanced cross-cultural awareness and shaped American foreign relations, especially relations with developing countries. Contributors include African American leaders and others who participated in Peace Corps or OCA programs.


The drum kit, which has only been around for around 100 years, is a popular instrument in many music genres such as pop, rock, and jazz. However, the road to owning a kit is expensive, both financially and space-wise. Also, drums are more difficult to move around compared to other instruments, as they do not fit into a single bag. We propose a no-drums approach that uses only two sticks and a smartphone or a webcam to provide an air-drumming experience. The detection algorithm combines deep learning tools with tracking methods for an enhanced user experience. Based on both quantitative and qualitative testing with humans-in-the-loop, we show that our system has zero misses for beginner level play and negligible misses for advanced level play. Additionally, our limited human trials suggest potential directions for future research.


is that they can be used to express the Fourier coefficients of the Poincaré series for the group GL(2,Q). As Kloosterman [Kl] pointed out, estimates of the Kloosterman sums lead to bounds for the Fourier coefficients of modular forms (see also Selberg [Se]). To estimate S(a, b; c) one easily reduces to the case c = p and p ab, with p prime. Salié [Sa] explicitly calculated S(a, b; p) when m > 1 and Weil [W1] proved that |S(a, b; p)| ≤ 2√p as a consequence of his proof of the Riemann hypothesis for curves. Thanks to Deligne [D], we now have efficient techniques for estimating exponential sums such as S(a, b; p). Paradoxically, the simpler case of exponential sums over Z/pZ with m > 1 is in some ways less well understood. Smith and Loxton [Sm1, Sm2, Lo-Sm1] generalized Salié's methods and Katz [K1] interpreted such results as a stationary phase formula. We take Katz's point of view, proving and generalizing his statement in Section 1. Our statement is very convenient for applications, and in many cases it gives sharper bounds than those of Smith and Loxton. We give several examples to illustrate the use of our theorem. The theory of Poincaré series for GL(3,Q) was developed by Bump, Friedberg, and Goldfeld [B-F-G] and extended to GL(N,Q) independently by Friedberg [F] and Stevens [S]. The Fourier coefficients of these Poincaré


The album covers collected in this volume reveal the stylistically influential cover art by Reid Miles for the legendary jazz label, Blue Note. With over 380 colour photographs, Blue Note captures the heart and soul of this musical genre while showcasing an impressive array of artists and performers, including Miles Davis, Herbie Hancock, Thelonius Monk, Sonny Rollins, and Art Blakey. Incorporating the best album covers from Chronicle's Blue Note and Blue Note II, and a few not seen in either, Blue Note: Album Cover Art is the most complete collection yet. Old timers and young jazz enthusiasts, as well as design buffs, will enjoy this exciting book of jazz memorabilia, accompanied by a concise history of the Blue Note record company.


A method for optimizing oligonucleotide probes for use in a hybridization assay, wherein said metodocomprende the following steps: a) providing a plurality of oligonucleotide probes in a hybridization matrix, b) providing serial dilutions of a genomic sample, wherein the genomic sample is marked; c) hybridizing genomic sample labeled and serially diluted with the probes on the array, so that seproduce signal intensity for each probe, wherein the hybridization step is performed unavez at least d) computationally generating data weighted regression from the intensity of producidapor each probe signal; ee) identify probes optimized from a plurality of oligonucleotide probes on an array dehibridacion for use in the assay using a probe selection algorithm; where muestranintensidades probes corresponding to the serial dilutions of the genomic sample, are reproducible, and related probes estanfuertemente not optimized.


The manual includes updated information on instructor requirements, the online examination, and simulation and debriefing. The new Instructor Manual for Neonatal Resuscitation has been completely revised for NRP™ hospital-based instructors and regional trainers who wish to present high quality simulation-based NRP™ courses. The manual features information relevant to NRP Instructors of all experience levels, including chapters about organizing supplies and equipment, setting up for all NRP Provider and Instructor courses, conducting simulation and debriefing, and performing administrative tasks.


The façade of St.-Etienne, Caen, has been described as the first façade harmonique, the model for many later façades in Normandy and the source of inspiration for the builders of the first great Gothic churches of the north of France. The façades harmoniques of these later churches are generally characterized by at least one prominent shared feature: the dominance of the façade design by twin western towers. St.-Denis is often singled out as having formed the link between Normandy--specifically St.-Etienne-- and the later churches of the Ile-de-France and its surrounding region. That certain early Romanesque buildings in England may have contributed to the development of the Gothic twin-tower façade has not been generally considered or recognized. It is here suggested that the two major churches in Canterbury, the cathedral of Christ Church and the abbey of St. Augustine, may have possessed two-tower façades that were the most advanced of their type at the end of the eleventh century, enjoying precedence over contemporary churches in Normandy in their forward-looking aspects. Indeed, it may be claimed that the essential forms of the Gothic façade harmonique had been established in England, prior to the construction of St.-Denis, at the two Canterbury churches and also, a little later, at Durham Cathedral.


Information on the features to be protected in a system of conservation reserves is an obvious requirement. The quality of the data base will primarily determine the effectiveness of conservation planning in protecting the full range of natural features in a region. However, the way in which data are used to make decisions on the locations of protected areas is also critical. Rigorous procedures for reserve selection can make the difference between achieving reservation goals or not. Research on reserve selection in New South Wales over recent years has concerned both data bases and procedures for guiding decisions. Reserve planning in many regions is based largely on some form of land classification like vegetation types or land systems. There are good reasons for using such land classes to guide the selection of reserves and to judge their representativeness. Nevertheless, they can have considerable limitations as a basis for protecting all the species in a region. These limitations are reviewed with references to more detailed discussions of particular issues. The paper also reviews a variety of procedures for selecting reserves which have been tested and applied in New South Wales. Some of the recent procedures are conceptually simple but very useful in identifying the requirements of reservation goals and demonstrating the options available to planners for representing particular features. Three principles are proposed which should underpin any attempt at systematic conservation planning.


The binaural recording technology based on an artificial head for the investigation of sound quality was introduced more than 25 years ago. In the meantime, this binaural technology is well established worldwide for a lot of different applications in the field of listening tests on the one side and measuring transfer characteristics of hearing protectors, head phones, telephone systems and others, on the other side. Most of the available artificial heads with respect to the geometrical dimensions are based on the ANSI S 3.36-1985. This standard has used geometrical data which were valid more than 75 years ago. In the meantime, the average dimension of people's head has changed. The question is how important the dimensions and the relationships of head, pinna and shoulder are to each other with respect to listening tests, spatial hearing and the measurement of sound events.


Abstract Grasshoppers are ecologically significant because many animals consume them as a major protein source and thus any change in their population dynamics may have detrimental effects on an ecosystem. This study evaluates effects of mercury (Hg2+) on the developmental periods of different instars of a common short-horned grasshopper, Oxya fuscovittata (Marschall). Newly hatched nymphs were fed foods treated with three sublethal concentrations of HgCl2 i.e., dose 1 (d1): 20 mg HgCl2/ kg dry weight in oats, dose 2 (d2): 40 mg HgCl2/ kg dry weight in oats, and dose 3 (d3): 80 mg HgCl2/ kg dry weight in oats, until they reached the adult stage. The experiment was conducted for two consecutive generations (F1 and F2), tested in the same way for the same variables, in order to observe if there is any additional adversity in the latter generation. As HgCl2 concentrations in food increased, the Total Rearing Time (TRT) for each instar significantly increased, whereas survival, adult body weight and adult life span significantly decreased. The results for the F2 generation almost always showed more severe effects than those of the F1 generation.


Retrospective analysis of our experience and the results from other centers indicate that development of a myocardial infarction contributes substantially to both early and late mortality in patients undergo, ing major peripheral vascular sureery. After ab- . . ? . dominai aneurysmectomy, hospital mortality ranged from 8% to 10% and the 5- and 10-year attrition rates were from 40% to 72%. In aortofe-moral bypass patients, the operative mortality rate was 4% to 5% with a late mortality rate from 31% to 91%. More than 50% of late deaths were cardiac related. These data clearly indicate that a new approach to evaluation and treatment was re-quired.


ABSTRACT Research Findings: The aim of this study was to investigate U.S. preschool teachers' math teaching knowledge in a specific content domain: counting and numbers. One hundred in-service and pre-service teachers participated in the study; they completed a questionnaire that is composed of learning scenarios and scenario-based math teaching questions. A mixed qualitative and quantitative method was applied in analyzing the data. Results show that the majority of U.S. preschool teachers failed to identify the concept of count-out that is embedded in a math game, the one-to-one correspondence error was the most identified counting error comparing to the other errors such as the cardinality principle error, and the knowledge of content and teaching appears to be more satisfactory than specialized content knowledge or knowledge of content and students. Practice or Policy: The study serves to fill some gap in addressing a pressing need in the field that is to identify and measure the unique body of preschool teachers' math teaching knowledge. The study also justifies that preschool teachers need intensive training such as a coursework that wholly focuses on math teaching in order for their math teaching knowledge to be more refined and teaching to be more knowledge-informed.


This paper concerns about the dynamic alignment for the strapdown inertial navigation system (SINS), especially in the case of no GPS assistance. A novel coarse alignment algorithm using external reference velocity in b-frame is proposed. To get the observation vectors of the optimization-based attitude alignment method, the velocity algorithm of SINS is derived in the inertial coordinate frame, so the Coriolis Effect can be excluded. Meanwhile, the real-time position of the SINS is approximately located, and the deviation of the gravity vector caused by the vehicle's displacement can be compensated, which further improves the alignment accuracy. Experimental results show that the proposed algorithm performs better than the existing algorithm and it can provide ideal initial conditions for the fine alignment.


Of 338 consecutive patients with cerebral infarction, aphasia in the acute phase was found in 96. Of these, 18 had totally recovered from aphasic speech disturbances when leaving the hospital. The patients were examined 2-8, in average 6 years after the onset of the illness. 39% of them had died, 27% still suffered from aphasic speech disturbances, while 32% were recovered from aphasia. In addition, disturbances in writing, reading, and/or calculation were observed in more than the half of the survivors. Of patients over 65 years of age 56% were dead compared with 32% of younger patients. Aphasia was observed relatively more in geriatric patients, and the recovery of them was poorer.


The new Cancer Drugs Fund has treated 15 700 patients since it began operating in July 2016, NHS England has reported.1 Just under a third of them benefited from earlier access to treatment than they would have had if the fund had not existed.

The original and now discredited Cancer Drugs Fund treated some 74 000 patients in its first four and a half years, so the annual treatment rate has not changed much. What sunk the old fund was its cost, which grew rapidly and exceeded the allotted budget. Set up in 2010, the fund had spent £1.27bn (€1.51bn; $1.64bn) by the time it closed in 2016.2

The new fund, which started in July 2016,3 is integrated into the National Institute …


Recent developments in triboelectric nanogenerators (TENG) make self-powered sensors possible and realistic by harvesting waste mechanical energy from the environment. This paper focuses on brief introduction on the basic principles and various working modes of TENGs, theoretical study and numerical analysis on TENGs in contact and sliding working modes. Numerical analysis is conducted using MATLAB for KAPTON-PMMA (Poly(methyl methacrylate)) TENG models, working on sliding mode and contact mode. The dynamic output characteristics of sliding mode TENG are evaluated with the varying input resistance value and dielectric gap distance.


The analysis of lipid peroxidation and oxidative status in 20 pregnant women with premature rupture of membranes (a gestation period of 22–34 weeks) who were hospitalized examined and treated at the Department of Pathology of pregnancy Perinatal Center of the Saratov Region in 2012 The objectives of this study included a comparative assessment of the content in the blood and amniotic fl uid of pregnant examined lipid peroxidation products – diene conjugates (DC) and malondialdehyde (MDA) and the quantitative determination of peroxides (OxyStat). The regularity at the same time increasing the total index OxyStat blood and amniotic fl uid, as well as an increase in blood and amniotic fl uid of intermediate products of lipid peroxidation: diene conjugates and MDA. The latter indicates the important role of local and systemic activation of free radical destabilization of membranes in the pathogenesis of prenatal rupture of membranes.