Globally, breast cancer remains the leading cause of death in females. While systemic therapy for breast cancer may work effectively in the early phases, for more than 10% of primary and 50% of metastatic cases, the disease eventually progresses, resisting treatments. To overcome this issue, recognizing markers of resistance as early as possible is critical. Microenvironmental factors influence tumors, and increased stiffness of the extracellular matrix (ECM) is associated with cancer progression. Additionally, neighboring cells such as non-neoplastic epithelial cells(that may constitute an important portion of the tumor microenvironment -TME) are suspected to affect tumors, but details on their impact are lacking. Here, we asked whether the response to increased ECM stiffness differed depending on the degree of aggressiveness of triple negative breast cancers (TNBC) and the presence of the non-neoplastic epithelium. We investigated two morphometric parameters, nuclear circularity and area (used in cancer pathology), and tumors' sensitivity to cisplatin to assess tumor aggressiveness- with TNBC cultured at normal (770 Pa) and increased (2000 and 3300 Pa) collagen I stiffness. Reduced nuclear circularity and increased heterogeneity for this parameter in the cancer cell population resulted from higher matrix stiffness and were associated with decreased sensitivity to the cytotoxic drug, cisplatin, notably in the more invasive cancer type. Interestingly, the impact of stiffness increase was reduced by the conditioned medium from the non-neoplastic cells. These findings warrant further investigations to identify whether changes in nuclear circularity that illustrate a global nuclear reorganization affect gene expression profiles linked to cell survival.
 Citation Format: Apekshya Chhetri. Exploring the impact of the tumor microenvironment on nuclear morphometry: Lessons learned for sensitivity to cytotoxic treatment [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P5-12-13.


A new propeller is designed in this paper for MAS's 40 m patrol ships.Particularly,the lifting-line and lifting-surface design method as well as the panel method are employed,and the given circulation distribution is adopted during the propeller theoretical design.For validation,both open water model tests and real ship tests were conducted.The ship tests were performed on two ships of the same type,yet one ship was equipped with an atlas designed propeller,while the other was equipped with the theoretical designed propeller.The parameters of speed,shaft power and aft vibration were compared and analyzed between the two models.It is observed that compared with the atlas designed propeller,the one designed by the theoretical method has a closer match with the ship,which is more efficient in propelling(with an increase of approximately 2% in the real ship propeller efficiency)and superior in noise reduction(with a decrease of about 5 dB in hull aft vibration).Therefore,the feasibility and reliability of the proposed design method in practical applications are successfully proved.


A 6.6 cm-inner-diameter permanent-magnets-expanding plasma source is connected to a large-volume diffusion chamber of about 76 cm diameter and 100 cm length, and is operated over a range of 20–300 mPa argon gas pressures. An rf power of 13.56 MHz for plasma production is maintained at 200 W and an expanding magnetic field of about 200 G in the source is provided by permanent magnet arrays. A potential drop of a few tens of volts is observed; a supersonic ion beam with energy corresponding to the potential drop is detected in the diffusion chamber. Radial investigation of the ion beam in the diffusion chamber indicates a detachment of the ion beam from the expanding magnetic field lines provided by the permanent magnets, at about several centimetres downstream of the source exit.


Supervisory Committee Lynneth A. Wolski, Supervisor (School of Exercise Science, Physical & Health Education) Dr. David Docherty, Departmental Member (School of Exercise Science, Physical & Health Education) Dr. Stewart Petersen, Additional Member (Faculty of Physical Education and Recreation), University of Alberta Dr. John O. Anderson, Outside Member (Department of Educational Psychology & Leadership Studies)


The analysis of the evolutionary characteristics of the formation of the human psyche in the process of anthropogenesis is conducted. The features of the differentiation of mental functions and psychological, socionic personality types are traced, including the formation of their complete integral system, which is connected by intertype relationships - socion. It is shown that the evolutionary differentiation of biopsychic modules identified by anthropologist and linguist Stephen Pinker, supplemented by the authors, and brought together by us into a single system of interactions among themselves, led to 16 differentiated types of psychoinformational interaction with the surrounding world in small protohuman groups. These types specialized in certain aspects of perception, identified by their specific mental structure, and interaction with the outside world, its properties, people, food prey, etc. At the same time, the formation of a system of intertype relationships or psycho-informational transactions took place in a person as a social being. This is traced by examples of dual and conflict interactions of the selected and described modules.


The invention relates to paint for casting titanium and titanium alloy as well as a preparation method thereof. The paint for casting the titanium and the titanium alloy comprises the following components, and the relative mass proportional relation of the components is as follows: the mass ratio of zirconium carbonate to refractory aggregate powder to surface active agent is 18-22: 75-80: 0.6-0.8; the refractory aggregate powder is zirconium dioxide or a mixture of zirconium dioxide and hafnium oxide; the surface active agent consists of sodium oxide, iron trioxide and silicon dioxide; the mass ratio of sodium oxide to iron trioxide to silicon dioxide in the surface active agent is 8-10: 1-2: 6-10. The paint has the advantages of simple components, stable performance, difficult gel appearance, long service life and low production cost.


In the last couple of years the main interests in cutting technology were focussed on the reduction of coolants in industrial application. The results of this duscussion was the development of dry cutting and minimum quantitiy lubrication. Nevertheless, lubricants lead to machining processes with high stability and are known to reduce the heat generation in machining. Focussing on the lubrication task of cooling lubricants, especially the impact of the additives on the process have to be analysed, because they are responsible for the formation of wear protecting and friction minimizing layers at the tool/workpiece interface. Such sorption and reaction layers can influence the chip formation positively and lead to reduced surface roughness and friction forces. The use of an advanced measuring technique made it possible to analyse the tribochemical influence of certain lubricants on the milling process.


Micromachining vacuum sensor can be formed using the semiconductor integrated circuit process. This sensor may be formed in the enclosure with micromachined components. Thereafter, the pressure in the enclosure may be measured using this sensor. .The


According to DL/Z 634.56—2004,the instructive document for conformance test based on IEC 60870-5 protocols series that applies to the communication of protection equipment,an introduction to the implementing details and designing mentality in the hardware and software design scheme of simulating the master station auto-test system is given.The hierarchical design and analysis of the applicable conformance of IEC60870-5-103 is made.The static structure of the software adopts modularized programming and the dynamic data exchange uses multi-thread technology.This system takes conformance test as its core while giving attention to the expansibility of the test tool.The test range covers the configuration parameter test of IEC 60870-5-103 protocol and function test.


Information based management is an important way to promote college education and research work.Despite notably increase investments in IT service in recent years, several problems still remain unsolved, making it hard to meet the demand of efficiency in college education. To solve problems including reminisce of traditional management, unbalanced development of software and hardware systems, and lack of standardized IT services, efforts should be made in clarifying construction ideas, innovating management schemes, pacing up software development,and unifying management standards, therefore move the IT management in college forward to a new level.


A74-YEAR-OLD MAN was referred to the outpatient clinic of the neurology department f or assessment of cognitive dysfunction, recent memory problems, hallucinations, abnormal behaviors, and speech disturbances with subacute onset. His medical history was remarkable for hypertension. He had smoked for 20 years. Neurologicalexaminationfindingsshowed alteration in mental status, cognitive impairment, and psychiatric symptoms, including hallucinations, confusion, mood lability, and disinhibition.Anelectroencephalogram showed no abnormality. Cerebrospinal fluid analysis was normal except for a mild elevation in protein content (0.47 g/L; normal range, 0.15-0.40 g/L). A cytological examination of cerebrospinal fluid showed no malignant cells. Results ofthecerebrospinalfluidcultureand viral serological tests were normal. Initial cranial magnetic resonance imagingrevealedabilateralandsymmetrical increase in volume and T2 signal intensity of the hippocampi and parahippocampal gyri, as well as the amygdalae (Figure 1). These areas were hypointense on T1weightedimages,withnochangein signal intensity after administration of intravenous contrast. No abnormality was noted on diffusionweighted images. These findings were suggestive of limbic encephalitis (LE), which is diagnosed with increasing frequency in paraneoplasticdisorders.Achestx-rayfilm, followed by computed tomography of the chest (Figure 2), showed a left-sided hilar mass with spiculatedmargins.Bronchoscopyandbiopsyresultsyieldedthediagnosisof smallcellcancerofthelung.Thepatient was started on chemotherapy. During follow-up, his neurological symptoms did not improve. COMMENT


The subordinating conjunction although is frequently used in English and is considered easy for students to master by many Chinese English teachers. However, errors are often found in Chinese EFL learners although output during pedagogical practice. This paper aims to explore and analyze common errors of although in Chinese EFL learners writing. The study is a corpus-based analysis launched under the computer-aided error analysis framework which is a new practice developed from the error analysis hypothesis. Errors of although found in texts from the Chinese Learner English Corpus (CLEC) are extracted and analyzed. Qualitative and quantitative analyses are conducted in the study. According to the findings, there are four major types of although errors found in Chinese EFL learners writing but/yet addition, punctuation errors, although misuse, and omissions and blends. Factors such as interlingual difference between English and Mandarin Chinese, intralingual interference within the English language system, pedagogical neglect in English classrooms and different cognitive styles are potential causes of Chinese EFL learners although errors.


The nonlinear shallow water equation is used for simulate the wave run-up on Phuket beaches due to the 2004 Indian Ocean Tsunami. Compared with field survey reported and data published in the literatures, the results of the developed numerical model shows good agreement in wave run-up heights, wave velocity, and inundation distances.


XTRAOCULAR MUSCLE PALSIES in Wernicke's encephalopathy are attributeti to a lack of thiamine (1-3) and usually respond to replacement therapy although the recovery time varies in different subjects (2, 3). It has been suspecteti that other nutrient deficiency may influence responsiveness. lntieed, recently patients who exhibited no laboratory evidence of a dieficiency of this vitamin (4-6) have been reported with eye signs anti other features of this condition. The present studiies were undertaken to assess further causes for variation in the time period required for eye signs to disappear following thiamine therapy in patients with Wernicke's encephalo-


This study aimed to identify the social representations of adoption by homosexual couples in the Brazilian reality. Participants where 589 adults of both genders, aged between 18 and 69 years (M=27.43, SD=9.0) from diverse backgrounds. Structured interviews and sociodemographic questionnaires were used and were analyzed using the IRaMuTeQ software, which organized the social representations into classes of lexical proximity. Results showed, a Descending Hierarchical Classifi cation, with two classes in the corpus of same-sex parent adoption and fi ve classes in the corpus about childhood development. These mainly highlighted positive social representations, always seeking the best for the adoptee as the justifi cation, however, unfavorable positions found refl ected the fear that the child would not be able to cope with the family model. In this sense, it is believed that the social representations about adoption by homosexual couples documented in this study indicate concepts that could support social interventions that increase the civil rights of homosexual parents.


In case of deafness, electrical cochlear implants (eCIs) bypass dysfunctional or lost hair cells by direct stimulation of the auditory nerve. However, spectral selectivity of eCI sound coding is low as the wide current spread from each electrode activates large sets of neurons along the tonotopic axis. As light can be better confined in space, optical cochlear implants (oCIs) promise to overcome this shortcoming of eCIs. This requires appropriate sound processing and control of multiple microscale emitters. Here, we describe the development, characterisation, and application of a preclinical low-weight and wireless LED-based multichannel oCI system for hearing restoration and its companion to its sister eCI system. The head-worn oCI system enabled deafened rats to perform a locomotion task in response to acoustic stimulation proving the concept of multichannel optogenetic hearing restoration in rodents.


This year this minitrack explores the increasing importance of e-governance and the challenges for governance associated with the adoption and use of information technology in public administration. The importance of collaboration and new forms of governance to the success of e-governance projects are the core issues discussed in two of the papers. The question of value creation and ethics in e-government deployment is also addressed in the papers selected for the track.


In this paper, the friction properties of each layer by ball on disk test. Zdol fractionated Zdol (MW=2000/spl sim/6000) and Z03 (MW=3840) are used in this study.


In order to eliminate the hysteresis error of piezoceramic servo tool during non axisymmetric curved surface turning, three feedforward controlling mathema tical models have been established, i.e. voltage increasing model, peak voltage dropping model and arbitrary point voltage dropping model. After many feedforward controlling compensation experiments, the maximal displacement error is 0 05 μm. The results of the experiments indicated that the way of compensating the displacement error based on the feedforward controlling mathematical models can lower the hysteresis error greatly during machining, therefore the precision of non axisymmetric curved surface can be improved.


HELLP occurs in 0.5%–0.9% of all pregnancies. About 30% of the cases happen within 48 hours after delivery. Women with postpartum HELLP syndrome have significantly higher incidences of complications. Because of the absence of classical signs of preeclampsia, it can confuse physicians and lead to delay in diagnosis. Therefore, it is associated with serious maternal morbidity. We present two cases of acute postpartum HELLP syndrome after caesarean section following severe preeclampsia. Our cases were successfully managed with the timely diagnosis and therapy.


"An Intelligent Speed Adaptations (ISAs)" system is into-vehicles system which help driver consistence with as far as possible. The system has ability for either notice driver or the restrictions them by surpassing a present speed limits. GPS innovation gets utilized for adjust speed base upon vehicles situation onto the expressway. By inquire about directed to a great extent in European nations, the usage of ISA can possibly essentially lessen the occurrence and seriousness of road injury. In the course of the most recent couple of year there have been developing enthusiasm for ISAs, & the quantity of the ISA researches & preliminaries expanding around the world. The paper presented outcomes by notice system which tried acknowledgment & adequacy for warning ISAs systems into Malaysia. Measurable examinations that were led for deciding viability for the system & surveys were utilized for deciding acknowledgment of system. These outcomes showed that warning ISAs added towards decreases into the speed. These surveys result uncovered a critical acknowledgment of the system. The test outcomes what's more, client assessment has demonstrated that the proposed arrangement give a reachable and a differentiating approach, contrasted with the current road wellbeing systems.


In 1927 when Mr. Edwin A. Link, arguably the father of flight simulation, began his association with aviation he became deeply concerned with the time, expense and hazards associated with teaching someone to fly. For him and everyone else learning to fly at the time there was little or no 'ground' schooling before first flight. He felt that many skills necessary for flying safely could be learned on the ground with the aid of an appropriately designed and constructed training device. Also in 1927, on the other side of the country, Philo T. Farnsworth, arguably the 'forgotten' father of television, electronically transmitted the first image of a photograph using a crude electro-optical apparatus he had conceived of many years earlier. Later, at sometime during the 1950's these two technologies converged to produce the first semblance of what we think of today as a flight simulator visual system. Since then the continued development and adaptation of these two core technologies has created a large gamut of visual system designs for flight simulators. In this paper the technological evolution that has occurred in flight simulation visual systems will be outlined, the current state of technology will be previewed and the future of these visual systems will be pondered.


Purpose. The study purpose was to implement a stroke-specific, care coordination home telehealth (CCHT) programme for US veterans with stroke and their family caregivers. Methods. In a non-randomized open trial using a mixed methods design, we tested the utility of a stroke-specific, home telehealth programme with 18 veterans and 14 caregivers for 14 days. Programme questions assessed physical impairment, depressive symptoms, and fall prevalence among veterans, and burden level among family caregivers. Nine veterans and six caregivers completed post-programme interviews exploring their experiences with telehealth. Results. During the 14-day trial, 55% of the veterans screened positive for depression at least once, 36% of the caregivers had clinically significant burden, half of the veterans and caregivers reported post-stroke concerns, and 90% believed post-stroke contact from a care coordinator would have been helpful. In the interviews, seven veterans indicated they had fallen or almost fallen post-stroke. Themes centred on tailoring CCHT to individual needs, coordinating with support services, identifying safety issues, and providing information about stroke prevention. Conclusions. Home telehealth offers innovative ways to target post-stroke rehabilitation programmes to the needs and concerns of patients and their caregivers, and should include regular real-time contact between stroke patients and their healthcare providers.


To govern inactively is the essence of Chinese ancient management culture, and super-leadership is a new leadership trend in the modern west. According to these two theories, the highest-level of leading activity should carry on the active super-leading on the basis of dialectical thinking of Dao and realize the inactive super-leading through practicing naturally. Then we should focus on the following three aspects, i.e. constructing the super-leading culture of governing inactively; improving the leading ability of each subject in the activity; establishing a "self-organizing" mechanism, to achieve the leadership of Let it be, yet everything is accomplished.


The engine bay and exhaust system of modern day vehicles consists of components, made out of different materials with different thermal conductivities. The heat transfer across the interface between two components in contact with each other is significant to determine their surface temperatures. This phenomenon becomes more critical for components which are made from materials with a lower thermal conductivity.
The effect of thermal contact resistance on the surface temperatures of these components is analysed. Different parameters that affect the value are studied and their values are determined from literature.
Component level analysis is carried out using physical tests and simulations. The complete vehicle simulation was then carried out by coupling thermal simulations with a CFD code. The criticial components which were affected by thermal contact resistance were identified in the engine bay and exhaust system.
A method to estimate the value of contact resistance was developed based on material properties. A simulation was run with the estimated values of contact resistance and the results were found to correlate better to wind tunnel tests.


Based on our analysis of descriptions provided by four EHR vendors on their EHR usability efforts, we provide three recommendations aimed at improving the usability of health information technology and reducing clinician burnout. First, EHR vendors need to dedicate increased attention to the design of the entire sociotechnical (work) system, including the EHR technology and its usability as well as the interactions of the technology with other system elements. Second, EHR vendors need to deepen and broaden their understanding of the work of clinicians and care teams by using diverse and mixed method. Third, in collaboration with health care organizations, EHR vendors should engage in cycles of continuous design and learning in order to improve the usability of health IT.


Focal dermal hypoplasia (FDH) or Goltz syndrome is a rare genodermatosis, characterized by multiple abnormalities of ectodermal and mesodermal origin. We present an infant with focal dermal hypoplasia who, besides having a constellation of anomalies commonly encountered in patients with this syndrome, manifested additional unusual features such as cleft lip and palate.


Abstract As a pilot site under the primary-care Increasing Access to Psychological Therapies (IAPT) Long Term Condition/Medically Unexplained Physical Symptoms (MUPS) project, patients with MUPS were offered cognitive behaviour therapy (CBT)-based treatments or attendance at a mindfulness-based stress reduction (MBSR) programme. This study aimed to gain an understanding of the views and experiences of MUPS patients that received CBT-based therapy or MBSR within an IAPT service and to investigate the relationship between their experiences and health outcomes measured on self-report questionnaires. Thematic analysis was used to analyse data gathered via semi-structured interviews with 11 patients. Data collected from three self-report measures were considered in relation to key features of participants' reported experiences and patterns identified. Four main themes emerged: (1) something needs to change; (2) making connections between physical symptoms and mood, thoughts or activities; (3) sharing experiences and feeling understood; and (4) reflections on treatment experience. Participants generally reported a positive experience of treatment and felt better able to cope with their symptoms, although treatment did not necessarily result in reliable change in symptoms as measured by the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7) and Work and Social Adjustment Scale (WSAS). This novel model of treatment appears to be acceptable for this patient group although evaluation of the pilot should consider the ability of routinely used measures to capture the value of treatment to patients, including improved coping with symptoms.


Administrative contract is an effective means for modern countries and governments to administer its social things. In this paper, the penman analyzes the conception of the contract in Public Law, the standard for i-dentification, the balance between public power and private right and redress for private right.


BACKGROUND AND PURPOSE
The patient's perspective is becoming increasingly important for endpoints in studies about multiple sclerosis. However, relapse data generated from the patient's perspective in combination with an independent documentation by the physician are scarce. Our objective was to compare self-reported relapses by the patient to physician documented relapses within a routine clinical practice setting of quarterly visits.

METHODS
Two-year data (n=1921 patients) were extracted from two prospective, non-interventional, multicenter cohort studies in Germany. The number of relapses independently reported by patients and physicians was analyzed. In addition, inter-rater reliability and measures of validity were evaluated. Patterns of associations were investigated in subgroup analysis of sociodemographic, clinical and patient-reported outcome measures.

RESULTS
Patients and physicians showed good overall agreement (Kappa=0.78, 95%-CI 0.76-0.80). Nevertheless, patients reported on average more relapses than physicians during follow-up (0.55 versus 0.44, p<0.001). Corresponding annualized relapse rates were 0.38 (95%-CI 0.36-0.39) and 0.30 (95%-CI 0.29-0.31), respectively. Differences between physicians and patients were particularly pronounced in patient groups with increased disability, decreased health-related quality of life or treatment satisfaction. The positive predictive value was 74.01% (95%-CI 71.85-76.07) and the negative predictive value was 98.86% (95%-CI 98.67-99.03).

CONCLUSION
Some disagreement on the occurrence of relapses appears in specific patient subgroups, where factors such as pseudo-relapses or confounding factors may have promoted over- or underreporting.


This paper uses factor analysis method to determine the influencing factor of college student entrepreneurial process, and makes assignment for influencing factors by Delphi evaluation, determines the extent and intensity of impact. In the end, it establishes the index evaluation system, and ultimately evaluates the college student entrepreneurial process by using fuzzy mathematical method.


The Adjoint Linearised Euler Solver of Karabasov and Hynes (2006), which includes an efficient iterative solution of linearised Euler equations in the frequency domain, has been extended to a 3D framework. Numerical tests performed for the problem of sound scattering from an axi-symmetric Gaussian jet flow show a very good performance of the method for a range of frequencies and observer angles as compared with the reference semianalytical solution. A new approach has been introduced for evaluating the source terms of the Goldstein acoustic analogy equations based on the second-order statistics provided directly from Large Eddy Simulation (LES). In comparison with the previous works, the new procedure is completely free from modelling assumptions, such as the functional behavior of the auto-covariance stress tensor or the dependence of the correlation scales of frequency. This makes the Goldstein acoustic analogy modelling based on LES practically applicable to general 3D flows and allows not only computing the far-field pressure spectra but also the reconstruction of effective volume noise sources. In comparison with the standard integral surface methods such as the Ffowcs Williams – Hawkings (FW-H) penetrable surface formulation, the new approach is potentially more robust since it has no sensitivity to the acoustic surface location. For the proof-of-concept study, acoustic predictions are made for two static single-stream co-axial jets at acoustic Mach number V /c = 0.875 that correspond to the temperature ratios T /T = 1 and T /T = 2.5. Comparisons with the reference penetrable FW-H solutions and the scaled QinetiQ experiment data are performed. The budgets of acoustic power spectral density for the individual source terms of the acoustic analogy model are also provided.


[1] This study presents an asymptotic solution of static displacements excited by a point dislocation in a spherical symmetric Earth model as an approximation of the dislocation theory for a spherical Earth model [Sun et al., 1996]. The solution is mathematically simple and physically reasonable since it reflects Earth sphericity and radial structure. Comparison of the asymptotic results with both the exact results and the corresponding flat Earth results shows that for any distance the exact results are approximated better by the asymptotic results than by the flat Earth results. For a homogeneous sphere, both theoretical and numerical investigations indicate that the solution is valid for all types of seismic sources and for an epicentral distance of at least 20° with a relative error less than 1% compared to results calculated for a spherical Earth model [Sun et al., 1996]. For a vertical strike-slip source, the asymptotic solution is valid for the entire Earth surface. For the 1066A Earth model, it is found that the asymptotic solutions are sensitive to the vertical derivatives of model parameters. The sensitivity can be used to study the vertical structure of the Earth. It is also found that the sphericity effect can be well reflected in the asymptotic solution, and can reach 20% discrepancy in the near field for a deep source. Owing to its mathematical simplicity, this solution can be applied easily to calculate coseismic displacement, just as the theory for a half-space Earth model like Okada's [1985].


The ongoing communicational transformation brought on by digital technology and the increasing imbrication of reticular ecosystems amplify their effects and changes in social life, defining new relationship configurations. The practices and trends of incorporating Information and Communication Technology (ICT) into education, published in the past five years, points to a trend of simply transposing everyday ICT into school processes, without taking into account the necessary pedagogical, technical and conceptual adjustments, nor other factors of the educational complexity. The literature reports inappropriate technology use in educational processes even when supported by intensive use of resources. This research project aims to contribute with the development of a new educacional model based on Integrated Cognitive Competences for incorporation of technology in the educational process as a way of overcoming these difficulties.


............................................. 2 Introduction......................................... 3 Materials and Methods............................... 5 Results............................................... 12 Discussion............................................ 28 Literature Cited..................................... 32 II. FUNGICIDES FOR CONTROL OF STRAWBERRY ANTHRACNOSE CROWN ROT IN SUMMER NURSERIES........................ 36 Abstract.............................................. 37 Introduction......................................... 38 Materials and Methods............................... 39 Results............................................... 45 Discussion............................................ 53 Literature Cited..................................... 56 III. EVALUATION OF FUNGICIDES FOR CONTROL OF STRAWBERRY FRUIT ROTS............................................ 59 Abstract.............................................. 60 Introduction......................................... 60 Materials and Methods............................... 62 Results............................................... 64 Discussion............................................ 70 Literature cited..................................... 74 VITA........ 77


The present situation of research on selective synthesis of xylanases for pulp biobleaching was reviewed in detail.The enzyme source of xylanase,multiplicity of xylanase,and the effect of cultivation condition such as carbon source,cultivation temperature,pH value and ratio of carbon to nitrogen on the synthesis of xylanases and cellulase were systematically discussed.In order to use the xylanases in pulp biobleaching effectively,carefully control of these cultivation conditions for the synthesis cellulase-poor xylanases was recommended.


Abtract : Water resources are an essential element, closely related to other types of resources such as soil, air and biological resources, which determine the development of a region or territory. Currently, the issue of sustainable management and use of water resources in river basins is an ur-gent requirement which is of great interest in many parts of the world and Vietnam as a whole. This paper presents the results of studies by various methods, water sampling methods, water quality analysis methods, WQI_Serepok informatics software application method to quickly provide suffi-cient information regarding water quality, helping management agencies to make appropriate de-cisions in the management and sustainable development of water resources in the Serepok river basin.


Abstract The complexity of industrial embedded systems is increasing continuously. Companies try to keep a leading position by offering additional functionalities and services. Systems are to be composed by multiple sensor, actuation and computation subsystems running in a coordinated way on a distributed platform. Due to the increment in processor power, it is possible to allocate a large number of functions in the same platform. This gives rise to mixed-criticality systems, when components with different criticality levels coexist in the same processor. This approach can lead to prohibitive certification costs. A better approach is to rely on partitioned systems, based on a hypervisor that isolates each of the virtual machines in the system. Components with different criticality levels are allocated to different partitions, in order to prevent interferences. The aim of this paper is to introduce mixed-criticality systems, to introduce the most challenging research topics, and to provide some background on the most promising techniques and research activities.


We analyze how performance metrics that contain equivalent information affect actual decisions. We consider two such performance metrics from supply chain management, days of supply and inventory turn rate, where one is the inverse of the other. We argue that individuals' assessment of performance is also affected by the metric as opposed to solely based on the inventory value that actually matters. We perform three laboratory studies and analyze how decisions are affected by the metric used to indicate inventory performance. The first study considers alternative inventory optimizations, out of which one must be selected. The second study analyzes a decision maker who must decide on the effort to invest in optimizing inventory of a specific product. The third study corresponds to the economic order quantity model. Our behavioral models suggest that decisions are affected by the metric that is used to indicate performance, and we find support for the predictions in laboratory experiments with human subject...


The forward exchange rate is widely used in international finance whenever the analysis of the expected depreciation is needed. It is also used to identify currency risk premium. The difference between the spot rate and the forward rate is supposed to be a predictor of the future movements of the spot rate. This prediction is hardly precise. The fact that the forward rate is a biased predictor of the future change in the spot rate can be attributed to a currency risk premium. The bias can also be attributed to systematic errors of the future depreciation of the currency. This paper analyzes the nature of the risk premium and of the prediction errors in using the forward rate. It will look into the efficiency and rationality of the futures market in Brazil from April 1995 to December 1998, a period of controled exchange rates.


Abstract Not Just Play will introduce the reader to the European Cultural Foundation programme "Art for Social Change". This programme is being carried out in partnership with the network of Soros Foundations, mainly in Central and Eastern Europe. The article offers some insights into the rationale behind the programme, its framework and the activities carried out within "Art for Social Change". It will close with some information regarding the evaluation of the programme.


Eight varieties of shallot, i.e. Probolinggo, Parman, Kuning, Biru-sawah, Biru-pasir, Tiron-sawah, Tiron-pasir and Bima, were tested for their yield potential at two different locations (sand-dune and rice-field) during wet season and dry season in 2002. The experiments were arranged in Randomized Completely Block Design with three blocks as replication. The experimental unit consisted of 100 plants planted with 15 cm x 20 cm spacing. The aims of this research were to identify the stability and adaptability of the tested materials. Adaptability and yield stability of each variety were determined based on stability model of Eberhart and Russell (1966) and Finlay and Wilkinson (1963) with a regression coefficient (βi), deviation from regression (δi) and yield of each variety as stability and adaptability parameters. The results of this research showed that varieties Probolinggo, Tiron-sawah and Biru-pasir were well adapted over all testing environments and their yields were stable. On the other hand, Parman and Kuning varieties were categorized as unstable varieties and well adapted in favorable environment, i.e. in the rice-field during dry season. Birusawah and Tiron-pasir varieties were adapted to unfavorable environment, especially in the sand-dune during dry season. Variety bima was not well to all the testing environments and the yield was susceptible to the environmental changes.


of regional economy transition the sustainable Abstract The high level of scientific, technological and socio-economic development in modern society poses a real threat to its existence. This is due to the intense importance of the environment. Against the background of such processes, the environmental condition of the Black Sea coastal area regions continues to deteriorate and does not fully depend on the timing of economic change. The main reason is the lag influence of the economy on the economic parameters of territorial subdivisions. The problem study of the regional economic complex transition to the sustainable development model in the period considered in the article involves finding an acceptable threshold level of economic and environmental policy, which is conducted by the territories administrations and identifying the boundaries of special states of the economic complex. The Ukrainian Black Sea coastal area regions are defined by territories with a pre-crisis economic situation and this determines the development of an appropriate strategy for sustainable development of this economic region. On the basis of the conducted diagnostics of ecological and economic condition of the Black Sea coastal area regions the tension of the economic situation, necessary parameters of its estimation that allows to start formation of regional strategy of sustainable development from scientifically substantiated positions is defined. Thus, to assess the quality of surface water, an index of water pollution was introduced and its gradation is given. activities and changes Using concept interpretation is given. region's economic standards The used the changes the The work Black each new positions,


The invention discloses a low-shrinkage medium-temperature-cured high-efficiency flame-retardant unsaturated polyester fiberglass reinforced plastic board and a preparation method thereof. The low-shrinkage medium-temperature-cured high-efficiency flame-retardant unsaturated polyester fiberglass reinforced plastic board is prepared from the following components in parts by weight: 50-60 parts of unsaturated polyester resin, 20-30 parts of a low-shrinkage additive, 1-3 parts of an accelerant, 0.5-2 parts of an initiator, 2-5 parts of a medium-temperature curing agent, 0.1-0.5 part of a thickening agent, 8-15 parts of a novel halogen-free flame retardant, 100-130 parts of inorganic filler, 2-3 parts of a release agent and 100-150 parts of fiberglass. The curing degree, the bending strength and the flexibility of the low-shrinkage medium-temperature-cured high-efficiency flame-retardant unsaturated polyester fiberglass reinforced plastic board can be improved; residual styrene in the fiberglass reinforced plastic board is reduced.


This paper focuses on analyzing the relationship between urban decorative sculptures and environment,points out the mutual relation between urban decorative sculptures and environment,such as mutual subordination,mutual influence,and harmonious coexistence,which has certain directive significance for creating or enjoying urban decorative sculptures in today's rapid urbanization situation.


Approach: There are two variants of our work: inter-voice morphing and intra-voice morphing. In the intra-voice morphing scenario, a single person's voice is recorded uttering a wide range of utterances. The speaker's phones are then morphed in time to generate new utterances of the speaker. We note that intra-voice morphing addresses the same problem that concatenative speech synthesis algorithms address, except that instead of simply re-ordering and concatenating original speech samples, intravoice morphing methods smoothly morph between the different recorded sounds. This will help to reduce the amount of recorded audio needed for speech synthesis systems. For example, current stateof-the-art concatenative speech synthesis systems require around 40 hours of recorded audio in order to produce natural-sounding speech.


About two years ago my little boy Antonio, who was then six years old, stopped me and said, "Mami, even a man can be a lawyer." My jaw dropped. He said, "Neil is a lawyer" Neil is the father of one of his close friends. I said, "Well, sure, mijo, even a man can be a lawyer." Since he was three years old, I have been the head of Equal Rights Advocates, a women's legal advocacy organization in San Francisco, and he spends a lot of time in my office. When people from my office get together socially to have a summer barbeque or a holiday party, all he sees are women. He sees Latinas, he sees African-Americans, he sees Asians, he sees lesbians, single moms, married women. In his small world, lawyers are women. I thought, "Wow, my own experience was that I never met a lawyer until I was in law school." In the community where I grew up in South Texas, if there were Latino lawyers, I certainly didn't know them. All of our parents were poor, had very low levels of education, and were fortunate if they had finished high school. As a child, the idea of becoming a lawyer wasn't even on my radar screen. I never thought about it as a possibility for my life it just was not thinkable. If you can't think of something, it's very hard to become it, to be it. Therefore, I think it's extremely important that we have visible role models that our children can see, so they can say, "Yeah, I can do that," or so a parent can say, "Yeah, mijo or mija can do that. She can be a lawyer, she can be a doctor."


An economical method for obtaining a nearly-optimal threshold for the block truncation coding (BTC) image compression algorithm is presented. Simulation results show that the PSNR performance of the proposed economic BTC (EBTC) method is very close to that of the optimised BTC (OBTC) algorithm, but EBTC only takes about half the computation time required by the OBTC algorithm.


The supercritical method for biodiesel production is critically examined. Operating conditions such as alcohol type, stoichiometry, temperature, pressure, and the presence of a catalyst and/or co-solvent are examined. The supercritical method is tolerant towards feedstocks containing large amounts of moisture and free fatty acids. High yields of methyl esters are obtained by using high alcohol ratios with high temperatures and pressures. The supercritical method is catalyst free and simplifies the recovery of glycerin as a co-product for biodiesel production. Some questions are posed, as this method is relatively new in the area of biodiesel fuel production.


We introduce a simple extensive-form algorithm for finding equilibria of two-player, zero-sum games. The algorithm is realization equivalent to a generalized form of Fictitious Play. We compare its performance to that of a similar extensive-form fictitious play algorithm and a counter-factual regret minimization algorithm. All three algorithms share the same advantages over normal-form fictitious play in terms of reducing storage requirements and computational complexity. The new algorithm is intuitive and straightforward to implement, making it an appealing option for those looking for a quick and easy game solving tool.


The invention relates to a method for producing fine glass articles consisting of low viscosity glass, in particular of glass with viscosities of approximately θ < 10 dPa s. According to said method, a low-viscosity glass mass is supplied to a lower tool (1), whereby the glass mass is compression moulded by joining an upper tool (4), which is located opposite the lower tool (1), with said lower tool (1). The inventive method aims to resolve the problem of rapid cooling, present in prior art, thus increasing the quality of the finished glass and allowing the production of fine glass articles by compression moulding. To achieve this, the inventive method is characterized in that the surface roughness (RZ) of the tools (1, 4) ranges between 5 and 15 νm and the glass gob (2) is preformed between the method step 'supply' and the method step 'compression' by acceleration forces, whereby forces of between 1 and 10 g (gravitational acceleration) are achieved.


This is a study of social mobility within the developing class structures of modern industrial societies based on a unique data-set constructed by John Goldthorpe and Robert Erikson. The focus is on the experience of European nations - western and eastern - in the period of the `long boom' following the Second World War; but the book also devotes separate chapters to examining the experience of the USA, Australia, and Japan. The authors combine historical and statistical approaches in their analysis of both trends in mobility and of cross-national similarities and differences. They show that wide variation at the level of actually observed mobility coexists with a surprising degree of constancy and commonality in underlying patterns of social fluidity. The empirical results of their study serve as the basis for a critical re-examination of current theories of mobility and for raising more general issues of the proper concerns and methods of comparative macro-sociology. This book is intended for teachers and postgraduates in sociology, social and economic history, social stratification, and the sociology of industrial societies.


In Part I of this two-part series, we focus on efficient use of motors, drives and pumps, both for process equipment and compressed air systems. Pharmaceutical manufacturing plants in the U.S. spend nearly $1 billion each year for the fuel and electricity they need to keep their facilities running (Figure 1, below). That total that can increase dramatically when fuel supplies tighten and oil prices rise, as they did last year. Improving energy efficiency should be a strategic goal for any plant manager or manufacturing professional working in the drug industry today. Not only can energy efficiency reduce overall manufacturing costs, it usually reduces environmental emissions, establishing a strong foundation for a corporate greenhouse-gas-management program. For most pharmaceutical manufacturing plants, Heating, Ventilation and Air Conditioning (HVAC) is typically the largest consumer of energy, as shown in Table 1 below. This two-part series will examine energy use within pharmaceutical facilities, summarize best practices and examine potential savings and return on investment. In this first article, we will focus on efficient use of motors, drives and pumps, both for process equipment and compressed air systems. Part 2, to be published in May, will focus on overall HVAC systems, building management and boilers.


Virginia Living Museum Executive Director Page Hayhurst has received the Excellence in Nonprofit Leadership award from Volunteer Hampton Roads for demonstrating excellence in meeting community needs.


Introduction This study examined the effectiveness of occupational performance coaching, which was delivered through telerehabilitation, in improving children with autism spectrum disorders (ASD) occupational performance, behavior problems, and prosocial behavior in addition to parental self-efficacy and quality of life. Method Forty-three children were matched and randomized to occupational performance coaching or waitlist groups. Occupational performance, parental self-efficacy, behavioral problems, and prosocial behaviors were assessed using the Canadian Occupational Performance Measure, Child adjustment and parent efficacy scale-developmental disability (CAPES-DD), the Short-Form Health Survey, and goal attainment scale. Results The intervention group showed greater improvement on occupational performance, specified goals, and behavioral problems. No progress was seen on the CAPES-DD prosocial behavior subscale. In addition, parental quality of life improvement was not maintained after the follow-up phase. Conclusion Occupation performance coaching, which was delivered through telerehabilitation, was effective on children with ASD occupational performance and parental self-efficacy, but it was not effective on the prosocial behaviors of these children.


The Colony of Sierra Leone originated in settlements of freed slaves on the West African coast carried out on the initiative of British philanthropists in the later eighteenth century. For over a century, British responsibility was as far as possible restricted to the small mountainous peninsula on which Freetown stands, and to certain nearby islands; but influence was inevitably obtained over nearby coast and hinterland, and during the nineteenth century some additional territories were incorporated in the Colony, though not always brought under effective administration. In 1896 the remaining regions not conceded to be under French or Liberian influence were proclaimed a British Protectorate; which also included, for administrative purposes, certain chiefdoms formerly part of the Colony. In this period, therefore, the term 'Colony' is applied to the peninsula and islands originally settled, with a few predominantly tribal areas around the river Sherbro; the term 'Protectorate' to territories the size of Ireland, which form the great bulk of the area marked 'Sierra Leone' on a modern map, and whose social organization was at this time exclusively tribal. At the beginning of 1898 British officials began to collect a House Tax which had been imposed on three of the five districts of the Protectorate. In February, resistance to the tax by certain Temne chiefs developed into open warfare in the north, and at the end of April a series of savage attacks took place on British and American subjects, mostly of African birth and descent, among the Mende and Sherbro people further south. These two outbreaks constitute the insurrection to be studied in this paper.


We propose a geometric approach to extract local properties of digital curves. This approach uses the notion of blurred segment 1. It is an extension of Reveilles' arithmetical approach 2 on discrete lines, more flexible, to take into account noise in digital images. This notion is also extended to the 3D space. Algorithms are presented to decompose a curve into a sequence of maximal blurred segments. A curvature estimator for 2D and 3D curves is proposed relying on this decomposition as well as a torsion estimator for 3D curves. All these estimators can naturally work with disconnected curves. They prove their efficiency in experiments and in comparisons with some well-known methods of the literature.


Abstract UAEU engineering faculty has initiated several research projects on renewable and alternative energy resources. In this talk I will discuss briefly recent research advances on power interface blocks between renewable energy sources (photo-voltaic or fuel cell) and the end user/load. In addition, research developments to enhance battery life span will be also presented. Also, two interdisciplinary projects on renewable energy for local UAE applications will be discussed. Finally, thoughts on successes and failures in collaborative research will be shared.


Kells 1988 was Ihefirst to point out Ihat Ihe ionic composition of lacustrine waters could exert an important effecl on the preservalion of organic matter in the sediments of these systems In lakes with high sedimentation rates thesediments become devoid of molecular oxygen at or very near the sediment water inlerface The rales of anoxic anaerobic decomposition of organic matter vary with Ihe amounl and Iype of organic matter being buried as well as withthe electron acceptor being reduced The amount of energy produced per organic molecule being oxidized is more formicrobial sulfate reduction Ihan formethane production Therefore where sulfale is abundant organic carbon should be more readily oxidized than where other anions such as Cl and HCO dominate the chemislry We have tested Ihis hypothesis by delermining in situ sulfate reduction via radioIabeIlechniques in sediments from Freefight Lake a Na Mg2 SO saline lake in southwestern Saskatchewan These data are then compared to sulfate reduction rate measurements from other sedimentary environmenls Of particular inlerest is our previous work on algal flat sedimenls from Na Mg2 CI salt lakes and pans in Bonaire N A The maximum suIfale reduction rale for the nearshore algal flat sediments of Freefighl Lake was 400 nmol ml d This is 2 to 2 5 limes lowerthan rales from similar settings in Bonaire even though the sulfale concentrations were 10 20 times higher at Freefigh Lake In addilion the S OC ralios of the Freefighl Lake sediments were extremely low indicating the lack of sulfate reduction in Ihese sediments Allhough Ihe 10taI reduced sulfur concentration increased with depth at Freefight Lake an extremely high percentage of this 10laI S2 is in theform of acid volatile sulfur This would nol have been predicted from the low sulfate reduction rates A number of importanl conclusions can be drawn from this work They include the following I sulfate reduction rates in sail lake sediments are nol solely dependent on SO 2 concentrations noron the ionic composition of thelake waters 2 even though the organic carbon concentrations of these sediments are high sulfate reduction is nol rapid and 3 Ihe low sedimentalion rate 0 03 cm yr may lead 10 the ulilization of the mosl metabolizable of the carbon present in the oxic zone by aerobic bacteria thereby slowing suIfale reduction rates


Abstract. The purpose of this application, under Articles 29 and 55.3.1 of the Code, is to remove the homonymy between two family-group names, coryninae of Hymenoptera (Insecta) and corynidae of Anthoathecata (Cnidaria). It is proposed to adopt the Greek genitive form Corynid- of the sawfly genus Corynis Thunberg, 1789 as the stem of the corresponding family-group name, giving corynidinae Benson, 1938. corynidae Johnston, 1836, a name for hydrozoans, would remain unchanged.


Acknowledgments. Preface. 1 Introduction. PART I LOCATING LAMENT AS OBJECT. Introduction. 2 For Crying Out Loud: What Is Lament Anyway? 3 Lament and Emotion. 4 Antiquity, Metaculture, and the Control of Lament. PART II LOSING LAMENT: MODERNITY AS LOSS. Introduction. 5 Cultural Amnesia and the Objectification of Lament in Bangladesh. 6 Modern Transformations. 7 How Shame Spreads in Modernity. 8 Crying Backward: Primitivist Representations of Lament. PART III REVIVING LAMENT: LAMENT AS KEY TROPE OF MODERNITY. Introduction. 9 Mourning Becomes the Electron's Age: Lamenting Modernity(ies). 10 Lament's (Post)Modern Vertigo: Floating in a Deterritorialized Media Sea. 11 Lament in a Postmodern World of "Revivals". 12 Conclusion. Notes. References. Index.


Software and globalization provide both opportunities and challenges to developing countries. Whether these opportunities are successfully utilized depends upon the availability of infrastructure and educational skills, a conclusion arrived at by many development debates over the past few decades. We will consider the impact of the software industry on development, drawing on the case of India. We show that in India, a number of factors have come together to contribute to the success of this industry, in spite of relatively poor infrastructure and education levels. In this case, however, the inadequacy of infrastructure and education have manifested themselves in an uneven spread of the benefits of this industry, leading to enclave-type development in urban centres in the southern and western parts of the country. While this is improving, the government has to take an active role to ensure a more even spread of the benefits accruing from this industry.


Thе article presents an analysis of the content produced by Sevastopol TV companies and studios. Based on Roskomnadzor data the authors provide a list of Sevastopol TV channels, describe the thematic and genre features of TV programs. The main research methods are TV channel broadcast monitoring and content analysis. The authors come to the conclusion that the TV space of Sevastopol is heterogeneous. Both state and private TV channels are present in the city media market. The authors demonstrate how depending on the form of ownership and the goals of the founders the editorial policy of TV channels and the thematic focus of programs change. Thus state TV channels cover more of the activities of the Executive and Legislative city government. Private TV channels address problematic issues of the population with some criticism of the authorities. The basis of the broadcast is informational and socio-political programs, the most common genres are interviews and news. The authors also describe video content produced by two organizations that are not registered as separate mass media, such as a branch of VGTRK – GTRK Sevastopol and a TV studio of the black sea Fleet of the Russian Federation.


Abstract River temperatures often surpass the thermal limits of juvenile Atlantic salmon (Salmo salar). Using thermal monitoring data to replicate a natural heat event, we investigated how cooler nighttime temperatures would affect how juvenile salmon cope with several days of heat cycling.


In the past 10 years, the price of molybdenum ore market in China slumped affected by many factors. Through the summary of the domestic form of supply and demand, the past trend of market prices, etc., the current domestic price trend of molybdenum ore, the development of the steel industry, national policies and other factors were analyzed to infer that the domestic price of molybdenum ore are expected to bottom out and slowly continue.


Carbon monoxide appears to be the leading cause of injury and death due to poisoning worldwide.1 A colorless, odorless, tasteless gas, carbon monoxide is produced by the incomplete combustion of any carbon-containing fuel. Prevention of carbon monoxide poisoning requires public education on the safe operation of appliances, heaters, fireplaces, and internal-combustion engines, as well as increased emphasis on the installation of carbon monoxide alarms.1 Despite the ubiquitous presence of carbon monoxide in our environment, its known threat to public health, and more than a century of scientific investigation, the mechanisms of injury and methods of treating carbon monoxide poisoning are . . .


In this article we propose a new method to deal with the derived categories of some semi-perfect k-algebras. This method gives us a unifying description of the derived categories of a branch class of algebras such as gentle algebras, some lannish algebras, of the Gelfand quiver etc.


Objective To investigate normal fetal heart rate in early pregnancy and assess the hypothesis that abnormal fetal heart rate is associated with fetal chromosomal abnormalities.


Abstract Two competing explanations of the role of test anxiety, cognitive interference or poor academic skills, are examined empirically using structural equation models of reading comprehension and mathematics. We examined the performance of 211 participants (96 males and 115 females) on two standardized achievement tests. Prior achievement (a proxy for academic skill), test anxiety, and their interaction were represented in the structural equation models as causal influences on performance. Results suggest that the cognitive component of test anxiety (worry) and prior academic achievement contribute independently, not interactively, to performance on both measures. Findings are discussed in terms of their implications for test anxiety theory and achievement testing.


We have observed the co-seismic electromagnetic phenomena such as earth potential difference (EPD) variation and atmospheric electricity (AE) variation at three observation sites in Akita Prefecture. In the strong earthquake of December 2nd, 2001, we observed clear signals of the EPD and the AE variation at all three sites. However, the amplitude of both observed signals at three sites are very different though with almost equal quake intensity at each site. The AE signal amplitude is increasing with the EPD signal one at each site. The model how both variation signals appear is proposed to explain the observed data.


Gas hydrates are abundant in sea sediments in regions of low temperatures and high pressures. Considering the conditions necessary for formation and stability of gas hydrates, and according to Levitus's data and Sloan's CSMHYD Hydrate Program, we derived water temperature depth equation and phase boundary equations. Assuming that the thermal gradient in the sediments of the southern South China Sea ranges from 59 to 90 (℃·km~(-1)), we obtain the function of the thickness of the gas hydrate stability zone (GHSZ) versus the water depth. According to the latest digital terrain map in the southern South China Sea, we obtain the maps of the calculated GHSZ thickness on the platform of GIS. For the study area, the maximal GHSZ thickness ranges from 230 to 355m, the volume of GHSZ from 5.7×10~(13 )to 9.5×10~(13)m~(3), the amount of methane from 2.451×10~(15) to (4.085)×10~(15) m~(3), and the resources of gas hydrates from 1.729×10~(13) to 2.169×10~(13) m~(3).


A study of the mode of action of sodium cyanate on the kidneys of adult rats has shown that its diuretic effect is due mainly to a decrease in the rate of water reabsorption by the tubules (Dicker, 1950). As had shown that sodium cyanate has a pronounced antimitotic activity, it was thought of interest to investigate whether other antimitotic substances like urethane or colchicine would have a similar diuretic effect and if so how they would affect the renal mechanism.


Reorganizing a layout entails a major adjustment to current layout and thorough planning is essential before a new layout implementation. This study is to reorganize current layout at dispatching area of a manufacturing industry which produces apparel products. Current arrangement at the dispatching area has brought to a poor efficiency rate of 48.74% that consumed 30.77 minutes to complete one dispatching job with distance travel of 162.83 meters. Witness simulation study is used in this project methodology and Facility Planning Process approach is applied in the experimental design to generate alternative layout. Result of the alternative layout has reduced the current time to 32.79% and only consumes 20.68 minutes to complete one dispatching job with shorter distance travel of 109.44 meters.


Progressive peripheral arterial disease developed in a 54-year-old woman who had been undergoing hemodialysis for six years for polycystic kidney disease. Upon diagnosis with peripheral aterial disease, she no longer qualified for the active waiting list for renal transplant. After successful


s 11 Psychology of Writing: the Role of AT in L2 Writing Majid Fatahipour* Assistant Professor, English Department, Parand branch, Islamic Azad University, Parand, Iran (Received: 6, October, 2016, Accepted: 4 September, 2017, Date of publication: October, 2017) The role of psychological factors in learning a second language is no secret. The relationship between the variables such as ambiguity tolerance which means continued efforts despite uncertainty has been measured with vocabulary competence level in some previous research. The present study investigated the relationship of ambiguity tolerance, particularly with writing block and measures of writing quality in second language. For this purpose, 120 randomly selected participants at advanced level of English proficiency in two universities located in Tehran, responded to ambiguity tolerance questionnaire. The scores obtained were then related to their scores on writing block questionnaire and the mean score of writing quality. The latter was obtained through scoring three academic essays written by each student based on a well-known scale of writing quality by Nation which displayed a significant and positive relationship with ambiguity tolerance. Writing blocks had a negative significant relationship with ambiguity tolerance.


In this paper we address the problem of measuring structural complexity of generic tangles of vortex lines in a fluid domain, by using a combination of geo metric and topological techniques. To this end new concepts based on the idea of structural 'tropicity' axe introduced to determine 'tubeness', 'sheetness' and 'bulkiness' of a vortex tangle and to evaluate the degree of topological entan glement. A number of cases are considered: from highly organised, coherent vortex regions, given by the embedding of vortex coils, knots and links on nested tori, to less organised vortical flows, such as tangles of chaotic vortex lines. Various measures of linking (and helicity) are presented as well as esti mates of writhing and crossing numbers based on geometric and topological information. Moreover, by using the concept of signature preserving flow we extend the definition of classical stability to include wilder vortex dynamics that during evolution preserve structural complexity. The tools and the new concepts presented in this paper axe useful for the classification and study of general flow fields and can be employed to develop computational techniques for measuring structural complexity. 1 Vortex structures as complex tangles of vortex lines Modelling and control of turbulent flows still defy mathematics for difficulty and complexity. Spontaneous formation and interaction of self-organized, coherent vor tex regions are generic features of turbulent flows (Vincent & Meneguzzi, 1991; Jimenez et al., 1993). Coherence (for a proper definition see §6 below) is essentially due to the strong correlation of dynamical properties (such as fluid pressure, veloc ity, vorticity, strain, etc.) confined to localized regions in the fluid domain V. These regions are occupied by extended, filamentary 'structures' in the shape of vortex tubes and sheets (see, for example, Schwarz, 1988; She et al, 1990; figure 1). These structures are present where vorticity w(X,t) = V x u(X,t) (where u(X,t) denotes


Cytokine storm syndrome is a general term applied to maladaptive cytokine release in response to infection and other stimuli. It occurs during graft versus host disease after hematopoietic stem cell transplantation.
                  Recent evidence suggested that, during the coronavirus disease 2019 (COVID-19) epidemic, the severe deterioration of some patient's health with Coronavirus Disease 2019 (COVID-19) was compatible with symptoms as they are known for the cytokine storm syndrome. The cytokine storm syndrome in COVID-19 is associated with the development and progression of macrophage activation syndrome (MAS), vascular endotheliitis like Kawasaki disease, and acute respiratory distress syndrome. Abnormalities of coagulation and fibrinolysis are known clinical features of COVID-19 or MAS. We reported previously that plasmin inhibition reduced GVHD associated lethality and prevented increases in inflammatory cytokines in mice. But the role of the fibrinolytic system and its key player, plasmin, in the development of COVID-19 is not well defined. Toll-like receptors (TLRs) might contribute to the pathogenesis of the disease.
                  We established a murine model of fulminant MAS by repeated injections of TLR-9 agonist and D-galactosamine in immunocompetent mice. We found increases in circulating urokinase and the angiocrine factor tissue-type plasminogen activator (tPA) levels during the progression of fulminant MAS in mice, which causes the enhanced conversion of the proenzyme plasminogen into plasmin. Genetic and pharmacological inhibition of plasmin counteracted MAS-associated lethality and other related symptoms. We show that plasmin regulates the influx of inflammatory cells and the production of inflammatory cytokines, chemokines, and proteases like soluble forms or membrane forms of matrix metalloproteases generating an amplification loop. Based on these data, we hypothesize that COVID-19-induced vascular endothelial dysfunction causes the aggravation of COVID-19 leading up to cytokine storm or MAS syndrome, endotheliitis, and hypercoagulability with the induction of disseminated intravascular coagulation syndrome(Fig.1.). In summary, we propose that plasmin and potentially MMPs inhibitors might offer a novel treatment to control the deadly cytokine storm syndrome in patients with MAS or COVID-19, thereby preventing multiple organ failure.

                           Figure

                  Disclosures
                  No relevant conflicts of interest to declare.


Introduction Several endoscopic innovations have been developed recently to improve detection and characterization of colorectal polyps. Flexible spectral imaging colour enhancement (FICE) is a form of image enhanced endoscopy which enhances the visualisation of mucosal structures and microcirculation by the selection of spectral transmission with a dedicated wavelength. Methods Various electronic databases were searched for articles reporting on detection and characterization of colonic polyps comparing standard while light endoscopy and FICE. The pooled mean differences in total numbers of polyps, adenomatous polyps, flat adenomas, and hyperplastic polyps detected was calculated. Additionally, pooled sensitivity, specificity, positive and negative likelihood ratio, diagnostic odds ratio and pooled area under the receiver operating curve was calculated. A fixed effects model was used unless there was significant heterogeneity. Publication bias was assessed using Funnel plots and Egger's test and heterogeneity was assessed using Cochran's Q and the I2 test. Abstract PTU-033 Table 1 Detection of polyps with FICE Variable tested Pooled difference in means (95% CI) p values All polyps 0.132 (–0.064 to 0.328) 0.188 All adenomas 0.033 (–0.056 to 0.122) 0.468 Flat adenomas 0.077 (–0.099 to 0.254) 0.389 Hyperplastic polyps 0.104 (–0.072 to 0.280) 0.248 Abstract PTU-033 Table 2 Characterization of polyps with FICE Variable tested Pooled sensitivity (95% Cl) Pooled specificity (95% Cl) Pooled positive likelihood ratio (95% Cl) Pooled negative likelihood ratio (95% Cl) Pooled diagnostic Odds ratio (95% Cl) Pooled area under the receiver operating curve (95% Cl) Polyps < 5mm 85.9% (81.1 to 89.9) 85.5% (79.3 to 90.4) 5.4 (3.75 to 7.77) 0.17 (0.113 to 0.255) 32.81 (16.74 to 64.33) 0.914 +/- 0.017 Polyps < 10mm 91.3% (88.4 to 93.7) 74.7% (68.5 to 80.2) 3.86 (2.37 to 6.30) 0.115 (0.07 to 0.19) 37.08 (16.01 to 85.85) 0.902 +/- 0.08 All Polyps 90.4% (88.3 to 92.2) 86.9% (83.8 to 89.5) 5.96 (2.32 to 15.32) 0.135 (0.08 to 0.225) 45.56 (15.13 to 137.15) 0.945 +/- 0.025 Results 5 studies/2150 patients and 11 studies/2425 patients were included in the analysis for detection of polyps and polyp characterization respectively. There were no differences between FICE and standard colonoscopy for the detection of all polyps, adenomatous polyps, flat adenoma or hyperplastic polyps (Table 1). Table 2 lists the pooled diagnostic accuracy parameters for FICE. A random effects model was used in both because there was heterogeneity between the studies. Conclusion FICE does not seem to improve the detection rate of adenomatous polyps during screening colonoscopy. These results may partially be due to the small number of studies done so far using FICE. The pooled sensitivity and specificity of FICE does not meet the currently accepted criteria of the ASGE PIVI committee for use in routine clinical practise. Disclosure of Interest None Declared


We study the evolution of ideas related to creation of asset-backed currencies over the last two hundred years and argue that recent developments related to distributed ledger technologies and blockchains gives asset-backed currencies a new lease of life. We propose a practical mechanism combining novel technological breakthroughs with well-established hedging techniques for building an asset-backed transactional oriented cryptocurrency, which we call the digital trade coin (DTC). We show that in its mature state, the DTC can serve as a much needed counterpoint to fiat reserve currencies of today.


Augmented Reality video games such as Pokémon GO have a structure that encourages face-to-face social interactions between players, leading to potentially unique benefits for positivity (positive affect). This study investigated how participants' social interactions while playing Pokémon GO relate to their positivity after gameplay, crucially, after accounting for other non-social factors typically associated with positivity (participants' satisfaction with their game accomplishments). Participants were 108 Pokémon GO players, consisting of 54 dyads who signed up for the study together. Dyads were asked to play Pokémon GO together for eight sessions over 2 weeks, and to report on their gameplay experiences and positivity after each session. Multilevel modelling analyses revealed that more positive social interactions with their gameplay partner incrementally predicted participants' greater positivity post-gameplay. The association between positive social interactions and greater positivity was accentuated for participants who reported more frequent noxious mood states (depressive symptoms) at the start of the study. Findings suggest that above and beyond typical contributions such as achieving game accomplishments, there may be affective benefits for Pokémon GO players from the social interactions they have within the game, especially for those with noxious mood states.


Fuzzy clustering is an important branch of unsupervised classification, and has been widely used in patternrecognition and image processing. However, most of exiting fuzzy clustering algorithms are sensitive to initialization, andstrongly depend on the number of clusters, which limits their applications. Moreover , it also needs to know the type and number of prototypes in advance in multi-type prototype fuzzy clustering. To overcome these limitation, a metthod for acquiring apriori knowledge about clustering prototype is proposed in this paper,which obtains better performance in initializing multitype prototype fuzzy clustering.


: The routes and modes of transmission of Helicobacter pylori infection are still unproven. This is the most important part of its epidemiology. The fecal-oral (person-to-person, foodborne, environmental patterns) and the oral-oral (or gastro-oral predominantly in childhood and associated with vomiting) routes of transmission are assumed to be most likely. Recently, fecal transplantation has been used for treatment, but the possible transmission of H. pylori during oral capsule-based fecal microbiota transplantation was found negative. Occupational exposure occurs in hospital-acquired infections. One of the important modes of transmission is intrafamilial. A new family-based strategy for H. pylori infection prevention and control (FBCM) has been implemented in China. FBCM is more cost-effective and efficient for the prevention of gastric cancer. In the last year, studies on the prevalence of H. pylori among patients with oncological diseases (gastric carcinoma, colorectal carcinoma, pancreatic cancer, etc.), as well as the prevalence of mutations associated with antibiotic resistance, prevailed. The low level of awareness regarding one of the main risk factors for stomach cancer is striking. The knowledge of veterinarians about the zoonotic potential and risk of Helicobacter spp. are also insufficient. The gut microbiota could influence people's health and play a key role in the pathogenesis of Alzheimer's disease. A role for the complement component C3-C3aR signaling on brain functionality via H. pylori outer membrane vesicles passing biological barriers was found to be involved in the development of Alzheimer's disease. The optimal serum level of vitamin D has an independent protective effect against H. pylori infection.


In mobile ad hoc systems (MANET) blockage can happen between the two moderate hubs, when the bundle is exchanged from the source to the end. The blockage in MANET is primarily because of successive change to topology and high versatility of hubs, which prompt high loss of bundle. In specially appointed system the blockage control systems with TCP gets to be hard to handle following in ad hoc system there is high thickness of hubs in the system and there is regular change to topology in the system. In this paper to control the blockage in proactive source directing convention a lapse message is produced by the recipient to decrease the bundle sending rate. We are utilizing another control message i.e., Packet Error Announcing Message called


Each phase of age that the human being undergoes has special characteristics that distinguish it from other phases of growth.  The purpose of this study was to find out how influential psychology education is on adolescent education.  This research uses qualitative research methods, namely by utilizing sources from previous research and utilizing other sources that are library analysis as the main object of research.  The results of this study are the most appropriate learning model in adolescent psychology when facing various problems that relate physical, cognitive, emotional and psychosocial. It takes the role of parents, teachers and the community to recognize their world and provide opportunities to develop within their potential. Like a form of giving rules that are looser but still controlled because they are starting to be independent. Giving praise, appreciation, affection, and growing confidence in interacting with the environment. Confidence here is when a child feels he is capable and dares to be different and holds firm to his principles when what he brings is true. The role of the counseling teacher or counselor is not only focused on helping students with problems, but on assisting all students in developing a variety of potentials, including the development of learning/academic, career, personal, and social aspects.
 Keywords: Teenager, psychology , counselor


The article examines some key socioeconomic differences among the Hindu, Muslim, Scheduled Caste and Scheduled Tribe population living in the slums of Surat, based on data drawn from a complete enumeration of slumdwellers. The analysis indicates that such settlements are essentially 'heterogeneous' in character. The labour market — especially in the 'informal' or 'unorganised' sector that draws much of its work force from within such settlements — gets divided through participation of specific groups and communities in a wide range of jobs within select occupational categories. This reinforces the fragmentation of the urban informal labour market and tends to behave in an 'inclusive-exclusive' mode by absorbing labour within specific sectors of immediate as well as larger city economies.


Parkinson's disease (PD) is the fastest growing neurological disorder worldwide. PD has a huge impact on the patients quality life due to motor alterations and behavioral changes. The advancements in low-cost RGB-D cameras, such as MS Kinect®, generates the possibility to use low-cost devices to obtain motion data, and perform common PD test like gait analysis. In this research project, we explore the use of LSTM and one-dimensional convolutional neural network as a complement for clinical PD diagnose, this could be used to help the doctors and specialist in the complex process of objective PD diagnosis. For this, we automatically extracted features and time patterns of these signals, then we performed some deep learning models and as the main result, Conv LSTM model achieved an 83% prediction accuracy, an 83.5% precision, and 83.4% recall, being able to differentiate between PD and Non-PD gait samples.


Thrombotic disease complicates severe SARS‐CoV‐2 infection and is associated with increased morbidity and mortality. Various anticoagulation strategies have been evaluated in hospitalized patients to prevent complications. The impact of chronic anticoagulation before SARS‐CoV‐2 infection on the risk for subsequent thrombosis has not been systematically studied.


Sometimes statements made by people working in the finance industry when giving advice may be incorrect. This article examines how the tort of negligence applies to the making of these misrepresentations. Cases discussed include Hedley Byrne and Co Ltd v Heller and Partners Ltd [1964] AC 465, Mutual Life and Citizens Assurance Co Ltd v Evatt (1968) 122 CLR 556, Shaddock and Associates Pty Ltd v Parramatta City Council (1980-1981) 150 CLR 225, Tepko Pty Ltd v Water Board (2001) 206 CLR 1, Caparo Industries plc v Dickman [1990] 2 AC 605 and Esanda Finance Corporation Ltd v Peat Marwick Hungerfords (1997) 188 CLR 241.


Keratosis seborrhoeica is very common lesion and easy to be confused with some other diseases. We studied retrospectively 252 cases of keratosis seborrhoeica that accepted pathological examination in Xijing hospital from 1990 to 2000. The rate of correct clinical and pathologic diagnosis for seborrheic keratosis was 69.44%. It is proposed that (1)keratosis seborrhoeica can occur in any age; (2) dermatosis papulosa nigra is not a independent disease but represent keratosis seborrhoeica at its early stage.


This study explores the impact of Roger Fry's aestheticism upon "the New Biography",of which Lytton Strachey is the representative.Lytton Strache contributes to biography in that he gets rid of Victorian biography's dullness,achieves the truthfulness in biography and once more brings biography back into the field of art.By examining Roger Fry's aestheticism,the paper maintains that Lytton Strachey's success is realized out of his conception of biography,which is buttressed partly by Roger Fry's artistivision which insists on the artistic autonomy,artistic penetration into life,detachedness on the artist and the artist's means of expression.However,"the New Biography" is to some extent is too idealistic to be deprived of influences from both outside and within.


A brand that invests in good relationships with employees and collaborators is more likely to grow and stand out in the market. Put this way, this study seeks to assess the foundations of a great corporate culture and the importance of motivating employees to the point of making them feel part of the business. After the analysis of theoretical concepts, an exploratory study is presented, through in-depth interviews with employees of an asphalt paving company in Taquaritinga/SP, whose objective is to verify how they feel when working in the company and what makes them feel motivated. What we see is that the more the managers invest in a good corporate culture and in a good relationship with their team, the greater the potential for the company to progress, both in terms of market share, but above all in its image of credibility in front of its audiences.


Although graft survival rates in kidney transplant recipients have improved over the years. Cardiovascular disease remains the major cause of death after kidney transplantation. Therefore, relevant control of dyslipidemia is important for both the prevention of cardiovascular disease and protection of graft function.


【The changes of hydrogenation properties of $LaNi_5$ by hydrogen charging condition were investigated using the P-C-isotherm curves, DSC(Differential Scanning Calorimetry), GC(Gas Chromatograph), X-ray diffractometer. As a results of static hydrogen charging, the hydrogen storage capacity gradually decreased and the plateau region severly slopped. Most of the degraded properties could be restored by the annealing treatment. The degradation of hydrogen storage capacity was related with the formation of stable hydride, which was not dehydrided at room temperature.】


A symmetrically crossed-loop antenna featuring very high radiation efficiency across the entire LTE frequency bands for metal-rimmed smartphones with only 2 mm ground clearance is proposed, analyzed, and verified. The employment of even and odd modes is utilized to achieve wide bandwidth across 698–960 MHz (low-frequency spectrum), 1710–2170 MHz (middle-frequency spectrum), and 2300–2690 MHz (high-frequency spectrum). Empirical analysis confirms the crossed-loop topology results in a 180° phase shift of the electric current distribution on the ground plane, resulting in enhancement of the radiation resistance. As a result, the devised LTE antenna exhibits more than 48% to 75% total system efficiency across the entire band of interest, which is the highest efficiency reported in literature for metal-rimmed smartphones with extremely small ground clearance.


Community empowerment in the urban context has become a public discourse in the urban development perspective. Participation, inclusiveness, and collaboration encourage community empowerment in achieving equal urban welfare. This paper focuses on Kelompok Usaha Bersama or Joint Business Group (KUBE) community empowerment program, an initiative of the central government in collaboration with local stakeholders. The implementation of the KUBE program, which was specifically assigned, was examined in the Yogyakarta city area. By using the collective capability approach as a research lens, two findings were raised. First, the implementation of KUBE in Yogyakarta is an illustration of community empowerment policies in translating collective capabilities. Second, in realizing collective capability, an agency is required in the form of collective awareness and strong leadership.


Wax is considered to be by-products of biofuel production from lignocellulosic biomass and agricultural processing plants. Although, attempts to find applications of waxes obtained from these sources have been made, yet, little proportions of cases were successfully practical in industrial applications due to lacking of wax characterization data. This research aims to characterize wax properties of three types of lignocellulose biomass; Rice straw (RS), Sugarcane bagasse (SB) and Napier grass (NG); obtained from Soxhlet extraction technique with hexane solvent. The chemical and physical properties of waxes were analysed by Fourier Transform Infrared analysis (FT-IR) analysis and Differential Scanning Calorimeter (DSC) suggesting the similarity of properties between NG and SB waxes. To test the effect of wax on biofuel production, both dewaxed and non-dewaxed biomass were pretreated with diluted alkali and enzymatically hydrolysed by cellulase. The results showed that the combination of dewaxing and alkali pretreatment increased the cellulose proportions in biomass compared to alkali pretreatment for 21.8%, 10.1% and 16.1% in RS, NG and SB, respectively. Additionally, the combined dewaxing and pretreatment improved the saccharification yields of RS, NG and SB for 5.84%, 35.03% and 26.10%, respectively. Altogether, the existence of wax clearly showed the negative effect on biofuel production, thus dewaxing process should be further considered to be included to improve the biorefining process.


Academic studies in industrial location can be broadly categorized into three groups; theoretic studies, empirical studies, and case studies. Theoretic .studies derive an optimal state of location from hypothetical conditions with a deductive approach. Empirical International Facility Planning: Theory and Practice


Background and purpose:  RhoA kinase (ROCK) participates in K+ depolarization (KCl)‐induced Ca2+ sensitization of contraction. Whether constitutive, depolarization‐ or Ca2+‐activated ROCK plays the major role in this signalling system remains to be determined. Here, we determined whether Bay K 8644, a dihydropyridine that promotes Ca2+ channel clusters to operate in a persistent Ca2+ influx mode, could cause ROCK‐dependent Ca2+ sensitization.


The objective of the Competitiveness for Tourism Development Project for Cabo Verde is to create the conditions necessary to increase investment into and diversification of the tourism sector. Seeking to harmonize and streamline the implementation of projects financed by development partners, the Government decided to move and centralize its main implementation unit (UGPE – Unit for the Management of Special Projects), from the line Ministry of Economy and Employment into the Ministry of Finance. This effectively brings together the procurement and fiduciary responsibilities in one unit, UGPE, which is now handling several projects across sectors, including this Project. The UGPE keeps the same team, and handles other WB projects, and hence this change is not expected to affect its fiduciary capacity, which remains adequate to implement the project.


A study was undertaken on 50 patients admitted in Govt. General Hospital, Kurnool with acute cerebrovascular disease by using a pretested questionnaire. Parameters studied were age, sex, blood pressure, diabetes mellitus, smoking, alcohol, and hypercholesterolemia. 30(60%) patients gave the history of hypertension in the past and were on treatment, apart from 10 more patients recorded a high blood pressure (>140/90) at the time of admission, making a total of 40(80%) patients with hypertension. Out of 40 cases of hypertension, 30(75%) had cerebral infarction and 10(25%) had cerebral hemorrhage. 18 patients gave the history of diabetes, and 14 more had blood sugar more than 140 mgs% at the time of admission, making a total of 32(64%). Out of 30 cases of diabetes, 20(66%) had infarction and 10(33%) had hemorrhage. 25 (50%) patients were in the habit of smoking at a frequency of 5-25 cigarettes per day. Out of 25 patients with smoking 20(80%) had infarction and 5(20%) had hemorrhage. 16 patients gave the history of alcoholism. Out of which 7(43.7%) had infarction and 9(56.3%) had hemorrhage. Out of the 25 patients with smoking habit 16 were hypertensive patients and 9 patients revealed raised serum cholesterol. Out of 16 patients with alcohol habit, 11 were hypertensive patients and 5 had raised serum cholesterol. Out of these 11 hypertensive patients 5 had infarction and 6 had hemorrhage. The 5 patients who had raised cholesterol 3 had infarction and 2 had hemorrhage. Out of the 32 diabetes cases, 21 had hypertension, and 11 had raised serum cholesterol. Out of 21 hypertensive's, 12 had infarction and 9 had hemorrhage. Out of 11 patients who had raised serum cholesterol, 8 had infarction and 3 had hemorrhage. INTRODUCTION: Stroke is defined as a focal neurological deficit of sudden onset due to nontraumatic vascular lesion. Stroke rank first in frequency and important among all neurological disorders of adult life. it is the most frequent cause of death of neurological origin. Almost all elderly people have blockage of some small arteries in the brain and 10 % of the people have enough blockage to cause serious disturbance of brain function, a condition called stroke. If for any reason the blood flow is critically reduced below 15 ml per 100g per min. the resulting ischemia with hypoxia, when sufficiently prolonged, may cause death of neurons and glial infarction (1). Strokes are classified into: 1. Ischemic strokes: a) with cerebral infarction b) with cerebral ischemia 2. Hemorrhagic strokes 3. Strokes of undetermined origin Multiple risk factors are involved in the pathogenesis of stroke. The present study was undertaken to know the various risk factors involved in the causation of stroke. AIM OF THE STUDY: To study the risk factors involved in the causation of stroke.


The invention discloses a herbicidal composition containing fluazifop-p-butyl and quizalofop-p-ethyl and application thereof. The fluazifop-p-butyl and the quizalofop-p-ethyl serve as main active ingredients of the herbicidal composition, the mass ratio of the fluazifop-p-butyl to the quizalofop-p-ethyl is 1-70:1-80, and the fluazifop-p-butyl and the quizalofop-p-ethyl account for 5 to 85 percentof the total mass of the herbicidal composition. The herbicidal composition is applied to preparation of herbicides for controlling postemergence weeds in a soybean field, and particularly has an obvious effect when used for preparing herbicides for controlling various grass weeds in the soybean field. Compared with single-component herbicide, the herbicidal composition delays the weed resistance, has broad herbicidal spectrum and acts for a long time on the premise of improving the herbicide effect, and is safe for rape and afterculture crops.


The nonspecific low back pain is a condition has negative impacts in the economic and social spheres, since it directly relates to labor factors. The purpose of this study was to analyze the workers' experiences nonspecific low back pain. This was a research qualitative; in seven workers with nonspecific low back pain, of both sexes, aged over 18 years. For data collection, a semi-structured questionnaire was used. The interviews were recorded in audio and then transcribed and analyzed by the technique of content analysis. After analyzing the data, two categories of analysis were found: Discomfort in activities of daily living is discomfort in work is relationship of low back pain with functional capacity and quality of life the work. The low back pain reflects in many contexts of the lives of employees, not only their functions at work, but also other situations of daily life.


As mythological characters,both Christ and Prometheus love man and possess the spirit of enduring sufferings for him,and can be called"Saints"and"Martyrs",In terms of religious doctrine,however, they are each others heretics. The former embodies mans realistic concern for himself,whereas the latter reflects mans ultimate concern for himself. Nevertheless,both take"man"as the starting point,and have their own humane implications,which originate from normal human feelings and accord with humanity. Therefore,the two characters of heterogeneous categories become the source of spirit of Marxist construction of personality,which,in turn,shows that Christian culture possesses its specific humaneness.


INTRODUCTION
Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).

DESIGN
The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).

MATERIAL AND METHODS
We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva.

CONCLUSIONS
We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree.


Recently, economic model has been widely applied in cloud platforms for regulating virtual resource sharing. In the economic model, resource pricing scheme plays a key role for managing the relationship between cloud users and cloud providers. In this paper, we present a novel pricing scheme for virtual resource provision with aiming at improving resource utilisation and reducing operational costs for cloud providers. Unlike previous studies, the proposed pricing scheme applies producer-retailer-client model to describe the procedure of virtual resource trade and provides the optimal pricing solution by using gaming theory. Extensive experiments are conducted in a real-world cloud platform, and the results demonstrate that the proposed pricing scheme outperforms other approaches in terms of the increased profit and the reduction of variance of virtual resource prices.