text:
I took the jump this weekend and just signed up.
It's flipping awesome! I'm currently terrible at it and may have accidentally sent random people a fourth of July pic this morning. But that's part of why it's so enjoyable. It's stress free.
Who are your favorite people to follow on snapchat?! My user name is PatriciaBFrance . :) Can't wait to see you there!
|Mandatory post picture. Isn't that the cutest little baby bum you've ever seen? ;)
Changing the subject now... Advice please?
I'm considering purchasing a domain name, but not sure whether I should go with Patriciabinfrance .com or Patriciabaret .com .
I've noticed a ton of people just eventually switch over to using their full name anyways, but I also like "Patricia B in France."
Any opinions on this???
Thanks! xoxo


text:
Who We Are
At SASHA we provide supportive services and transitional housing to adults with severe and persistent mental illness.
SASHA is comprised of three houses that offer 8 long-term beds and 16 short-term beds.
All three houses are situated inside the London Road community, within close proximity of one another.
Our Mission
The Southern Alberta Self - Help Association (SASHA) is a non-profit community organization whose mission is to promote the independence of persons with mental illness by means of transitional and long-term housing through supportive programs and activities.
Our Vision
A world where adults with mental illness and addictions live in and contribute to the community with a sense of self-worth and equality.

subset: commoncrawl


text:
I Would Like to Live In the Country Instead of the City
Personal Stories, Advice, and Support 202 People
What I want the most is to live away frompeople, maybe a small village that's fairly spread out with only few people that is sustaining itself. Every person in the village has it's own thing that he/she shares with the rest of the village and in return gets something back he/she isn't good at or such. For example, you...
Ichki 22-25, M 1 Response 1 Apr 20, 2015
i would love to live in the country.not the messed up part of the country where i live. I'd live in a little village in England.
CallmeHopelessNotRomantic 36-40, F 4 Apr 20, 2015
Live In The CountryLive in the country,That'd be great,Who knows?What might come my way,I'm a free agent.
lazycrazybasket 46-50, M 0 Feb 5, 2012
There is less people around meso it is quiet. It is also a shame fantasy can not meet reality for me. One of my dreams is to grow bigger. Being giant would be so cool, and being on the country side, there will be less people to scare.
Profweird 22-25, M 1 Apr 20, 2015
I Am Always The Little Girl Dreamin'I hate living in the city! I live right across from a hospital, barf, there's a helicopter that flies above my house 24/7! And ambulances going up and down the streets! Firetrucks too! Ugh. I hate it! When I grow up I am movin' to the country! I'm going to have cats, dogs, and...
TopKitten 13-15, F 0 May 19, 2012
Fun In The ValleyIt was fun living in the valley. When the streams came down from the mountains, the laurel, and flowers blossomed so magnificently. It looked like a flowered paradise. We all marveled at the beauty around us. A heavenly place on earth with wonderous angelic beauty. I never...
Alicehath 56-60, F 0 May 1, 2013
I want a house on a couple acres.Just big enough to run a subsistence farm. I want peace, privacy, and sustainability.
CobaltStorm 22-25, F 2 Responses 2 Apr 21, 2015
If I Had A CarI had to stop driving many years ago, when I realized that I am a hazard out there, due to physical and emotional limitations. Not to mention financial limitations.If I had a car, I would live way out in a field somewhere. I'd love the peace that would bring; but I would have to...
Serenitree 70+, F 0 Oct 13, 2012
I'm country girl at heart,but I kinda like that city life too 🐷🌃
BeccaK1 18-21, F 1 Response 3 Jul 15, 2014
Coming From A City GirlHi my name is Lisa. All my life I have lived in the city. I would like a change of scene now. I liked being in the city but it was a bit stressful and noisy. I was always around people and animals. In the country it is quite a bit different. I think sometimes what would it be...
pearls37 22-25, F 0 Feb 8, 2013
I Do Live In the Country!Coming from a major city in California, my late husband and I had decided we wanted to move to Oregon. We were on our way to stay with some friends there when we decided after 12 hours of driving to stop and stay the night at another friend who lived in a little mountain town in...
uc4me2b 46-50 2 Responses 4 May 2, 2008
Enjoying BothI live in these two opposite worlds...lol. Though I stay longer in the city because of work.
1PrincessKai 46-50, F 0 Jan 13, 2011
but i dont do bugs and darknessor wild animals .
Alylovespuppies 18-21, F 1 Apr 21, 2015


text:
The Enchanted Tiki Room Wall Sign
Sign of the Gods
Follow this replica sign to the tiki tiki tiki room in your own home to see birds sing and flowers croon - or maybe just you and the family kicking back! Part of the 50th Anniversary celebration of Walt Disney's Enchanted Tiki Room. See more
It's added to your bag!
Not eligible for in-store reservation.
Magic in the details...
Created especially for Disneyland Resort
- Replica of Walt Disney's Enchanted Tiki Room signage at Disneyland Park
- Screen art print on composite wood backing
- Layered design for dimensional effect
- Celebrating 50 Years of Enchantment!
- Part of The Enchanted Tiki Room Collection, each item sold separately
The bare necessities
- Composite wood
- Approx. 23 1/2'' H x 28 1/4'' W
- Made in U.S.A.
Express shipping not available for this item. This item cannot be shipped internationally or outside the contiguous United States. It can only be shipped to a physical address, not to a P.O. Box, APO or FPO address. Please allow 3-5 weeks for delivery.


text:
Although they are not regular playoff partners, the Jesuit-Pasco matchup holds plenty of history for both teams.
Nineteen years ago, Jesuit fell to Pasco 28-16 in the Class 3A state championship played at Florida Field in Gainesville. In 2002, Jesuit scored a team playoff record 57 points in a 57-14 rout of Pasco in the opening round of the state playoffs.
Tonight, their seemingly every decade postseason meeting adds another chapter. At stake when Jesuit (11-1) travels to Pasco (12-0): A trip to the Class 5A state semifinals and a move closer to a possible state championship.
Jesuit comes into tonight's meeting on an 11-game winning streak. The Tigers, led by quarterback Tommy Eveld, rolled up 523 yards of offense in last week's win against rival Robinson. In fact, Jesuit's workmanlike approach all season has only been challenged by Robinson and Plant.
The Tigers topped Robinson 35-20 in last week's playoff game, which came after September's 21-7 Jesuit win. Take out the two Robinson games and Jesuit defeated its opponents by an average of almost four touchdowns per game.
Tonight, Jesuit will face Pasco's electric offense with plenty of options and quick-strike abilities. Jesuit's defense will have to slow Pasco QB Jacob Guy (35 TDs) and his trio of playmakers: RB-WR Janarion Grant, RB Emmanuel Grant and WR Trey Dudley-Giles, who have a combined 45 touchdowns.
But history (at least after 1992) isn't on Pasco's side. The Pirates have lost their last three playoff games to Hillsborough County opponents by a combined 147-41.
Meanwhile, in other playoff contests tonight, Gaither's road show continues tonight at powerhouse Lakeland, Plant continues its methodic journey through the Class 8A playoffs. Plant plays at East Lake, which is making its first appearance in the regional round of the playoffs.
And unbeaten and unchallenged Berkeley Prep is one game away from the Class 3A state championship contest. The Buccaneers (12-0) will be in Delray Beach on the east coast tonight to face a tough American Heritage team in a state semifinal meeting.
All kickoffs are scheduled for 7:30 p.m.
Plant (11-1) at East Lake (9-3)
LAST WEEK: Plant defeated Orlando's Dr. Phillips 49-13; East Lake defeated Palm Harbor University 33-26.
THE SKINNY: Plant's playoff march travels to Tarpon Springs tonight to face an East Lake team making its deepest postseason trip in school history. The Eagles are led by RB Tyler Lane, who galloped for 226 yards and four touchdowns in East Lake's thrilling 33-26 win against PHU. The effort was Lane's seventh straight 100-plus yard game. The good news for the Eagles is that they reached the region finals. The not-so-good news is that Plant coach Robert Weiner has only lost once in five region final appearances, the last in 2007. Those numbers may improve tonight with the play of Plant QB James Few, who has tossed 10 touchdown passes in the Panthers' two 2011 playoff wins.
Gaither (9-3) at Lakeland (12-0)
LAST WEEK: Gaither defeated Tampa Bay tech 17-14; Lakeland defeated Kissimmee Osceola 20-7.
THE SKINNY: Gaither's wild 17-14 playoff victory against Tampa Bay Tech made amends for its loss to the Titans by the same score during the regular season. Gaither QB Alex McGough likely will be looking for more big plays from WR Carlo Perello, who led the Cowboys with 26 receptions during the regular season. Still, Gaither coach Jason Stokes will need more rushing (just 14 yards last week) and fewer miscues (two lost fumbles and an interception). Lakeland, meanwhile, is in the midst of a typical run for the powerhouse program that owns six state championships, but none since 2006. The Dreadnaughts have a dynamic QB-WR tandem in Raheeme Dumas (1 TD rushing, 1 passing last week) and Ricquan Southward (who switched his college commitment from Miami to Ohio State this week). The last time Gaither visited Lakeland's Bryant Stadium for a playoff game? A 37-0 Lakeland romp in the second round of the 2006 playoffs.
Gainesville (10-2) at Armwood (12-0)
LAST WEEK: Gainesville beat Sunlake 21-14 and Armwood defeated Hillsborough 23-0.
THE SKINNY: The Hurricanes defense came up big last week, led by defensive back Cordero Dixon's two big plays. Dixon returned a fumble 49 yards for a score and took an interception back 51 yards for another TD. Gainesville's offense struggled against Sunlake, but showed in the region quarterfinal it was capable of big plays. Trailing 14-13 on their own 9-yard line with 90 seconds to play against Hernando, quarterback Mark Cato led the Hurricanes on a furious drive. He capped it off on a 33-yard TD pass to Chris Bivins with 40 seconds to play. Gainesville is ranked No. 10 in 6A.
Jesuit (11-1) at Pasco (12-0)
LAST WEEK: Tigers defeated Robinson 35-20; Pasco beat North Marion 31-28.
THE SKINNY: Pasco comes in undefeated while the Tigers haven't lost since week 1 against Plant. The Pirates will throw a balanced offense at Jesuit and are led on the ground by tailback David Emmanuel, who has rushed for 1,188 yards and 18 scores on the season. Quarterback Jacob Guy has completed 67 percent of his passes and has an impressive 35-5 TD to INT ratio. Trey Dudley-Giles and Janarion Grant both have more than 700 yards receiving. The Pirates erased an early-14 point deficit against North Marion and got a 21-yard Brandon Ray field goal as time expired to advance to tonight's game.
Berkeley Prep (12-0) at Delray Beach American Heritage (10-1)
LAST WEEK: Berkeley Prep defeated Fort Meade 21-0; American Heritage defeated Fort Lauderdale University 31-20.
THE SKINNY: Berkeley Prep has been untouchable this season, blasting opponents by an average of almost 30 points per game. Now that Nelson Agholor (211 yards rushing, two touchdowns) and the Bucs have vanquished an 0-3 recent record against Fort Mead with last week's 21-0 victory, they may finally have a challenge. In its first state semifinal game, the Buccaneers are facing an American Heritage squad that was the state runnerup in 1A last season. And just like Berkeley, the Stallions can score (38 points per game) and play defense (5 shutouts this season). American Heritage has a standout RB in Greg Bryant, who ran for 175 yards and two scores and returned an interception for a score in their big win against nationally ranked University. Berkeley will rely on standout LB Schyler Miles and the defense to keep this one close. The winner advances to the Class 3A state championship game on Dec. 10.


text:
The Cripple of Inishmann
Billy Claven lives on a small Irish island, and, like most of his neighbors, does a lot of nothing. Unlike his neighbors, Billy is disabled. He's The Cripple of Inishmaan. When a film crew starts to shoot a movie nearby, most of the residents see it as a diversion from their stagnant lives; Billy sees it as a way to escape his less than happy existence. "[Martin] McDonagh takes life's mundane moments and makes them funny and accessible for audiences," says director Steve Wallace via press materials. "We all understand why someone would want to be in a movie, but McDonagh shows the other side of the coin. Is 15 minutes of fame really what Billy wants? And will leaving Inishmaan really help him?" 8 p.m. April 20, 21, 24 and 28, and 2 p.m. April 22 and 29. University of Houston, 4800 Calhoun. For information, call 713-742-2929 or visit www.uh.edu.
Fri., April 20; Sat., April 21; Sun., April 22; Tue., April 24; Sat., April 28; Sun., April 29, 2012
Related Location
4800 Calhoun Rd.
Houston, TX 77004
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It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the site.
This step is noncompulsory but will drastically boost your chances of your profile getting noticed by other daters. Write a little about yourself, your hobbies and upload your best photo.
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Identified someone who looks suitable? Send a note to them or just a wink and take it from there. With a little luck you'll be on your way to locating the love of your life.
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text:
When you purchase a digital subscription to Cake Central Magazine, you will get an instant and automatic download of the most recent issue.
Here is my first cupcake cake. It was for my son and is of the Space Ranger emblem found on the sleeve of Buzz Lightyear's uniform. My son is a HUGE Toy Story fan and loved the cake. Emblem was free handed with bc icing.
Buzz Lightyear Rocket Ship
Buzz Lightyear
Buzz Lightyear Birthday
great work!
(if this is a private computer)
Yes please, register now!


text:
There was a report in October that said Miami was the leader for four-star defensive back Kendall Randolph. He quickly shot that down, and named a new favorite.
Premium Content
Subscribe today to read the full article and get everything Rivals has to offer.
- Member-only message boards
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- Exclusive coverage of Rivals Camp Series
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text:
Metabolic Abnormalities - HIV Infected and Uninfected Males
This study has been completed.
University of North Carolina, Chapel Hill
Information provided by (Responsible Party):
University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier:
First received: November 30, 2005
Last updated: February 27, 2017
Last verified: February 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been completed.
|Study Completion Date:
|August 2007
|Primary Completion Date:
|August 2007 (Final data collection date for primary outcome measure)


text:
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|Home » Discuss » Topic Forums » Religion/Theology
|Uncle Joe (1000+ posts) Send PM | Profile | Ignore
|Sat May-31-08 01:56 PM
Response to Reply #21
|25. I believe faith is a literal DNA ingrained requirement for survival. From Al Gore's
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Corresponding Document: Photo Gallery
Western Canadian businesses will now be able to access support to help bring their innovative new technologies to market, thanks to Western Innovation (WINN) Initiative, an initiative launched today by the Honourable Michelle Rempel, Minister of State for Western Economic Diversification.
WINN demonstrates our Government's commitment to ensuring that Canadian businesses continue to grow and generate high-value jobs across the West," said Minister Rempel. "
This initiative will help address a need identified by western Canadian businesses to help bring leading-edge innovations to domestic and global markets."
Under WINN, small- and medium-sized enterprises (SMEs) can apply for funding for a variety of tasks that are essential in taking a product from the R&D stage to the market, such as product testing and technology demonstrations, equipment purchases and installation, regulatory approval, marketing, and intellectual property protection.
Over the next five years, WINN will provide up to $100 million in repayable assistance to SMEs working to commercialize their products, processes, and services.
Getting a new idea into the marketplace can be a difficult prospect for a small business," explained Noah Decter-Jackson, CEO & Creative Director, Complex Games Inc., and Board Member of New Media Manitoba. "
The biggest challenge for western Canadian emerging businesses is the funding gap just prior to commercialization, where private investment becomes scarce and companies find themselves without the cash flow to take their innovation to the next level. WINN will help to bridge that gap."
By responding to the needs of our entrepreneurs and innovators with this targeted initiative, we are positioning them for long-term success and enabling them to emerge as leaders in a competitive global economy," added Minister Rempel.
The WINN Initiative through Canada's Economic Action Plan will support smaller firms across a range of sectors, including health and life sciences, clean technology and energy, aerospace and defence, nanotechnology, and information and communications technology. The Initiative is expected to help stimulate greater private sector investment, while also making it easier for innovative SMEs to secure funding.
Western Economic Diversification Canada, in partnership with the provinces, businesses, industry associations, and communities, promotes the development and diversification of the western economy, coordinates federal economic activities in the West and advances the interests of western Canadians in national decision-making.
For media inquiries, contact:
Emily Goucher
Office of the Minister
Western Economic Diversification
Telephone: 613-954-8097
E-mail: firstname.lastname@example.com
For Western Innovation (WINN) Initiative inquiries, contact:
WD Toll-Free Number:1-888-338-WEST (9378)
Teletypewriter (TTY): 1-877-303-3388
WD Website: www.wd-deo.gc.ca.
Subscribe to our news updates and keep up-to-date on the latest from WD. Follow us on Twitter at @WD_Canada
The Government of Canada is focused on creating jobs and economic growth for Canadians. Part of this challenge includes helping small businesses to develop innovative products and services, and get them to market. To help accelerate business-led innovation in Western Canada, the Harper Government is announcing the creation of the Western Innovation Initiative. WINN is a five-year, $100 million federal funding program for western Canadian businesses with less than 500 employees, to commercialize innovative technology-based products, processes or services.
Under this Initiative, small- and medium-sized enterprises (SMEs) that have new market-ready, technology-driven products and services may be eligible to apply for up to $3.5 million in direct, repayable funding. Eligible project activities for businesses include:
The application intake period will begin on November 9, 2013. SMEs interested in the initiative can find more information on WD's website.
In addition, SMEs wishing to participate in information sessions should contact the nearest WD Office or call 1-888-338-WEST (9378).
The West Means Business.


text:
A man had to be taken to hospital after falling from a yacht near Burnham Yacht Harbour.
The man, who fell after being hit by the boom just before 5pm yesterday, was quickly recovered by the vessel but sustained a back injury.
South Woodham Ferrers Coastguard assisted and ensured the safety of all personnel as the casulty was transferred to an air ambulance to be taken to hospital.
An East of England Ambulance Service spokesman said: "We were called at 5.45pm and dispatched a rapid response car, ambulance, hazardous area response team, paramedic officer and the Herts Air Ambulance.
"We treated a man in his 50s who suffered back and chest injuries.
"His injuries were thought to be serious but not life threatening and he was airlifted to the Royal London Hospital."


text:
$ 32.00
This set of two prisms is for you to share with a best friend, someone who needs a pick me up or just someone who deserves a smile!
Length 18."L
Pendant 1.75"
Suede, metal, glass
Made in Alabama
Style no. WI2G
$ 28.00
Wear your love for Lucy's Inspired with our NEW Inspired to Give Shirt.
A great addition with the Inspire to Give Necklace or Bracelet.
$ 36.00
Our Inspire to Give bracelet is two bracelets packaged together. Both bracelets are composed of small, varying colored beads.
We have created these beautiful bracelets in honor of Gabriella Maria Menotti, affectionately called "Gab Gab", who went to be with the Lord on December 20th, 2015 after a lifelong battle against a childhood disease.
Her relentless dedication, paired with the support of her family, friends and caretakers, was an inspiration to everyone. Even though her time here was short, Gabby so evidently touched the hearts and influenced the lives of many.
A portion of the proceeds will go to the United Mitochondrial Disease Foundation in her honor.


text:
|Comments on Photo
|Add Comment
By Boissal
From: Small Lake, UT
Sep 17, 2011
|That shade of pink definitely compliments the granite's tone... You could have drawn dicks instead of Xs for bolts and nobody would notice.
By Greg Gavin
From: SLC, UT
Oct 21, 2011
|If you like dicks that much Boissal then go for it.
By Charlie S
From: Ogden, UT
Oct 22, 2011
Halfway between the 170' rappel above the lunch ledge and the lunch ledge rappel itself: the shadows of the groove, above the chickenheads for S-direct, there is another bolted station.
This station landed us about 15 feet short of the lunch ledge rappel. Had to set up an interim anchor for easy down climbing to the rap.
By Greg Gavin
From: SLC, UT
Oct 24, 2011
|Charlie, did you use a 60m or 70m?
By Charlie S
From: Ogden, UT
Nov 5, 2011
|A 70m. Two BD #2's provided an adequate station to practically "walk" to the Lunch Ledge rap. A BD #3 would have been more desirable, however.
By Greg Gavin
From: SLC, UT
Nov 17, 2011
|Do you have any corrections to my crude rappel topo Charlie?
By Charlie S
From: Ogden, UT
Nov 29, 2011
I'm posting an edited picture with two additional anchors.
Since we only made it up half way, I am in no place to critique the upper half of The Thumb.
|Avg Score
|0.0 from 0 votes
|Your Score


text:
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Selected Miscellaneous Trailer - Other for sale in upcoming auctions.
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text:
Economy Masking Tape, 3/4" x 60 yards, 3" Core, CreamItem#: YYSP-MMM260018A | Model#: 2600-18A
Currently Out Of Stock!
You May Consider This Alternative
TAPE,MASK,ECON,.75X60YD Product Details
Consistent unwind, conformability and easy tear. Easy adhesion and removal. Can be written on with pen, pencil or marker. Tape Type: Masking.
What It Is And Why You Need It
- Economy masking tape.
- Consistent unwind, conformability and easy tear.
- Easy adhesion and removal.
- Can be written on with pen, pencil or marker.
Manufactured by: 3M
Warranty provided by: 3M
UPC No: 021200834325
Mfg Part No: 2600-18A
Box Size:
( Length:9, Width:5, Depth:5)
Shipping Weight: 2.8000 pound(s)
Click here for full warranty and support information
- 3M logos are registered trademarks of 3M. All others trademarks and copyrights mentioned herein are the property of their respective owners.


text:
The Cornew Innovation Fund is a pilot project program intended to support potentially high value, high risk research at the juncture of multiple disciplines.
The Cornew Fund has not only led to more than $14M new federal funding but has led to the development of a new class of therapeutics for treating Alzheimer's disease, new surgical glues, and surprising new insights into the earliest stages of fertilization and embryonic development.
The expectation is that these monies will be spent within one year of receipt and that the awardees will submit a brief report on the work performed for inclusion in the Annual Report of the Chemistry of Life Processes Institute. Awards are made possible through the philanthropy of the CLP Executive Advisory Board, typically on an annual basis with applications solicited in advance of the annual fall board meeting.
CLP Investigators Awarded
The Design and Synthesis of Prodrug-Procontrast Theragnostic Probes (2008)
Thomas J. Meade, PhD, Chemistry
Song Y, Zong H, Trivedi ER, Vesper BJ, Waters EA, Barrett AGM,Radosevich JA, Hoffman BM, Meade TJ,. Synthesis and Characterization of New Porphyrazine-Gd(III) Conjugates as Multimodal MR Contrast Agents. Bioconjugate Chemistry(2010), 21(12), 2267-2275.
Lee, S, Song Y, Hong BJ, MacRenaris KW, Mastarone DJ, O'Halloran TV, Meade TJ, Nguyen ST. Modular Polymer-Caged Nanobins as a Theranostic Platform with Enhanced Magnetic Resonance Relaxivity and pH-Responsive Drug Release. AngeChemie, Int (2010), 49(51), 9960-9964
Strauch RC, Mastarone D J, Sukerkar PA, Song Y,; Ipsaro JJ,Meade TJ, Reporter Protein-Targeted Probes for Magnetic Resonance Imaging. J Am Chem Soc (2011), 133(41), Society (2011), 133(41), 16346-16349.l
Manus LM, Strauch RC, Hung AH, Eckermann AL, Meade TJ, Analytical Methods for Characterizing Magnetic Resonance Probes. Anal Chemi (2012), 84(15), 6278-6287.
Schultz-Sikma EA, Meade TJ, Supramolecular chemistry in biological imaging in vivo, Edited by Gale PA, Steed JW, Supramolecular Chemistry: From Molecules toNanomaterials (2012), 4, 1851-1876.
Matosziuk LM, Harney AS, MacRenaris KW, Meade TJ, Synthesis, Characterization, and in vitro Testing of a Bacteria-Targeted MR Contrast Agent. Eur J Inorg Chem 2012 (12), 2099-2107.
Grant Awards:
USAMRMC W81XWH-10-1-282 5/1/10-4/30/13 Novel Magnetic Resonance Imaging Contrast Agents Targeted to Proteins Implicated in Breast Cancer
New Therapeutics for the
Treatment of Parkinson's Disease (2008)
Richard B. Silverman, PhD, Chemistry
Chang CC, Cao S, Kang S, Kai L, Tian X, Pandey P, Dunne SF, Luan CH, Surmeier DJ, Silverman RB. Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2. Bioorg Med Chem. 2010 May 1;18(9):3147-58.
Kang S, Cooper G, Dunne SF, Dusel B, Luan CH, Surmeier DJ, Silverman RB. Ca(V)1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nat Commun. 2012 Oct 23;3:1146.
Kang S, Cooper G, Dunne SF, Luan CH, Surmeier DJ, Silverman RB. Structure-activity relationship of N,N'-disubstituted pyrimidinetriones as Ca(V)1.3 calcium channel-selective antagonists for Parkinson's disease. J Med Chem. 2013 Jun 13;56(11):4786-97.
Kang S, Cooper G, Dunne SF, Luan CH, James Surmeier D, Silverman RB. Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics. Bioorg Med Chem. 2013 Jul 15;21(14):4365-73.
Grant Awards:
National Institute of Neurological Disorders and Stroke U01NS080409 9/1/12 - 8/31/17 A Novel Calcium Channel Antagonist for Neuroprotection in Parkinson's Disease (Co-Investigator)
Michael J. Fox Foundation for Parkinson's Research Agreement 11/14/08; 11/01/08 - 5/31/11 Identification of Novel Calcium Channel Antagonist for Neuroprotection in PD (Role: Co-I; PI: Surmeier)
RJG Foundation 11/1/09 - 10/31/10 Identification of a Novel L-Type Calcium Channel Antagonist for Neuroprotection in PD (PI: Surmeier) Co-Investigator
US Serial Number 13/490,591: Assigned to NU; Identifies Cav1.3 as a target for Parkinson's disease treatment
US Serial Number 13/504,893: Assigned to NU and Cambria; Covers composition of matter
US Serial Number 13/354,156: Assigned to NU; Use of this class of compounds for selective inhibition of Cav1.3
Lung Cancer Screening via
Analysis of Nanoarchitecture of Buccal Mucosa (2008)
Vadim Backman,
PhD, Biomedical Engineering
Roy HK, Hensing T, Backman V. Nanocytology for field carcinogenesis detection: novel paradigm for lung cancer risk stratification. Future Oncol. 2011 Jan;7(1):1-3.
Roy HK, Subramanian H, Damania D, Hensing TA, Rom WN, Pass HI, Ray D, Rogers JD, Bogojevic A, Shah M, Kuzniar T, Pradhan P, Backman V. Optical detection of buccal epithelialnanoarchitectural alterations in patients harboring lung cancer: implications for screening. Cancer Res. 2010 Oct 15;70(20):7748-54.
Grant Awards:
National Cancer Institute 1R01CA155284-02 9/26/11 - 7/31/15 Optical Nanoscale Analysis of Buccal Cells: Transforming Lung Cancer Screening
National Science Foundation CBET-0939778 8/1/09 - 7/31/11 EAGER: BISH: Biophotonics Technique for Detection of Lung Cancer
National Cancer Institute U54CA143869 9/15/10-7/31/14 Project 3 (PL: Marko) Coding, Decoding, Transfer and Translation of Information in Cancer.
Commercial Activity:
NanoCytomics, LLC
NSF SBIR Phase I: Partial Wave Spectroscopic (PWS) Microscopy: An Early Screening for Lung Cancer $150K
Cadmium Interference with
Signaling Pathways in the Mammalian Oocyte (2009)
Thomas V. O'Halloran,
PhD, Chemistry
Teresa K. Woodruff,
PhD, Obstetrics-Gynecology
Kong BY, Bernhardt ML, Kim AM, O'Halloran TV, Woodruff TK. Zinc maintains prophase I arrest in mouse oocytes through regulation of the MOS-MAPK pathway. Biol Reprod. 2012 Jul 1;87(1):11, 1-12.
Bernhardt ML, Kong BY, Kim AM, O'Halloran TV, Woodruff TK. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012 Apr 19;86(4):114.
Kim AM, Bernhardt ML, Kong BY, Ahn RW, Vogt S, Woodruff TK, O'Halloran TV. Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs. ACS Chem Biol. 2011 Jul 15;6(7):716-23.
Bernhardt ML, Kim AM, O'Halloran TV, Woodruff TK. Zinc requirement during meiosis I-meiosis II transition in mouse oocytes is independent of the MOS-MAPK pathway. Biol Reprod. 2011 Mar;84(3):526-36.
Kim AM, Vogt S, O'Halloran TV, Woodruff TK. Zinc availability regulates exit from meiosis in maturing mammalian oocytes. NatChem Biol. 2010 Sep;6(9):674-81.
Grant awards:
W. M. Keck Foundation 7/1/08 - 6/30/13 The inorganic signature of life: Signaling pathways in the mammalian oocyte
NIH/NICHD P01HD021921 9/30/09-8/31/14 Hormonal signals that regulate ovarian differentiation
CBC C2006-00997 6/1/09-5/31/12 Spark Award: Support for an innovative Cryo-STEM for element-specific imaging of cells and tissues
Molecular Basis of Self-Healing in Tissues Containing Histidine-Rich Proteins (2009)
Phillip B. Messersmith,
PhD, Biomedical Engineering
Fullenkamp DE, He L, Barrett DG, Burghardt WR, Messersmith PB. Mussel-inspired histidine-based transient network metal coordination hydrogels. Macromolecules. 2013 Feb 12;46(3): 1167-1174.
He L, Fullenkamp DE, Rivera JG, Messersmith PB. pH responsive self-healing hydrogels formed by boronate-catecholcomplexation. Chem Commun (Camb). 2011 Jul 14;47(26): 7497-9.
Holten-Andersen N, Harrington MJ, Birkedal H, Lee BP,Messersmith PB, Lee KY, Waite JH. pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2651-5
Brubaker CE, Kissler H, Wang LJ, Kaufman DB, Messersmith PB. Biological performance of ussel-inspired adhesive in extrahepaticislet transplantation. Biomaterials. 2010 Jan;31(3): 420-7.
Grant Awards:
NIH/NIDCR R37DE014193 7/1/11-6/30/16 Biologically Inspired Polymer Adhesives
NIH/NICHD RC1DE02702 9/17/09-5/31/12 Self-healing composites via novel biomolecular design and processing
Use of Novel Optics
Technology to Establish
Susceptibility, Resistance and
Recovery Indicators of Stony
Corals to Bleaching (2009)
Vadim Backman,
PhD, Biomedical Engineering,
Luisa Marcelino, PhD, Civil Engineering
Marcelino LA, Westneat MW, Stoyneva V, Henss J, Rogers JD,Radosevich A, Turzhitsky V, Siple M, Fang A, Swain TD, Fung J,Backman V. Modulation of light-enhancement to symbiotic algae by light-scattering in corals and evolutionary trends in bleaching.PLoS One. 2013 Apr 22;8(4):e61492.
Genome-Scale Identification of Protein Kinase Docking
Interactions (2011)
Eric L. Weiss, PhD, Molecular Biosciences
Weiss EL. Hippo unleashed! Proteome-scale analysis reveals new views of Hippo pathway biology. Sci Signal.2013 Nov 19;6(302):pe36.
Hsu J, Weiss EL. Cell Cycle Regulated Interaction of a Yeast Hippo Kinase and Its Activator MO25/Hym1. PLoSOne. 2013 Oct 21;8(10):e78334. PMCID:PMC3804511.
Strickland D, Lin Y, Wagner E, Hope CM, Zayner J, Antoniou C, Sosnick TR, Weiss EL, Glotzer M. TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods. 2012 Mar 4;9(4):379-84.
Nguyen Ba AN, Yeh BJ, van Dyk D, Davidson AR, Andrews BJ, Weiss EL, Moses AM. Proteome-wide discovery of evolutionary conserved sequences in disordered regions.Sci Signal. 2012 Mar 13;5(215):rs1.
Grant Awards:
Chicago Biomedical Consortium C-035 8/1/12-7/31/14 Genome scale identification of protein docking interactions
Conferring Thromboresistance
to Decellularized Vascular Grafts (2011)
Guillermo Ameer, PhD,
Biomedical Engineering,
Jason Wertheim, MD, PhD
Hoshi RA, Van Lith R, Jen MC, Allen JB, Lapidos KA, Ameer G.The blood and vascular cell compatibility of heparin-modifiedePTFE vascular grafts. Biomaterials. 2013 Jan;34(1):30-41.
Grant Awards:
Wertheim, JA: 2014 NMF Dixon Translational Research Grant "Development of a Small Caliber Vascular Graft Using a Tissue Engineering Strategy"
Using Perturbations of Heavy
Metal Homeostasis to Treat
Nematode-Borne Neglected
Tropical Diseases (2013)
Erik Andersen, PhD,
Molecular Biosciences
Thomas V. O'Halloran, PhD,
Iron-Based Molecular MRI
Thermometers for Monitoring
Tumor Ablation Therapy (2013)
T. David Harris, PhD,
Andrew C. Larson, PhD
Jeon I-R, Park JG, Haney CR, Harris TD, Spin crossover iron (ii) complexes as PARACREST MRI thermometers. Chem. Sci. 2014; 5(6):2461-2465.
Park, JG, Jeon I-R, Harris TD, Electronic effects of ligand substitution on spin crossover in a series of diiminoquinonoid-bridged Feii2complexes. Inorg. Chem. 2015; 54(1)359-369
Development of Alstonine-Based Treatments
for Schizophrenia (2013)
Karl A. Scheidt,PhD,
Herbert Y. Meltzer, MD,
Lee A, Younai A, Price CK, Izquierdo J, Mishra RK, Scheidt KA, Enantioselective annulations for dihydroyquinolones by in situ generation of azolium enolates. J. Am. Chem. Soc. 2014; 136(30):10589-10592
Identifying Network-Level
Signatures of Tumor-Induced
Macrophage Functional
Heterogeneity (2014)
Neda Bagheri, PhD,
Biomedical Engineering
Joshua Leonard, PhD,
Chemical Engineering
Understanding Targeting and
Binding of Therapeutic
Nanoparticles to Plasma
Membranes (2014)
Teri Odom, PhD, Chemistry
Igal Szleifer, PhD, Biomedical Engineering
Targeting the Ubiquitin System: Nedd4-1 Ubiquitin Ligase as a Promising Drug Target (2014)
Alexander Statsyuk, PhD,
Photochemical interrogation of synaptogenesis (2015)
Yevgenia Kozovoristkiy, PhD,
Thomas Meade, PhD,
Exploiting nature's
pharmacopeia: mellpaladines
as new serotonin antagonists (2015)
Karl Scheidt, PhD, Chemistry
Geoff Swanson, PhD
Towards Elucidating RNA Cotranscriptional Folding Pathways from RNA Polymerase II
Julius Lucks, PhD Chemical and Biological Engineering
Yuan He, PhD Molecular Biosciences
Immunotheranostic Nanostructures for the Early Detection and Treatment of Cardiovascular Disease
Evan Scott, PhD Biomedical Engineering
Thomas Meade, PhD Chemistry
Vinayak Dravid, PhD Materials Science Engineering


text:
Egg and Sausage Muffins
Nothing beats egg, sausage and cheese on an English muffin in the morning. But since my husband and I both work, there isn't enough time to make these tasty breakfast sandwiches. Instead, I prepare a week's worth of the sandwiches on the weekend and store them individually in the freezer. We simply put two sandwiches in the refrigerator the night before work, then pop them in the microwave the next morning. A few minutes of cooking on the weekend pays off all week long! —Terri Vogel, St. Germain, Wisconsin
© 2017 RDA Enthusiast Brands, LLC


text: The Mini BMX by Venom brand was created after seeing these awesome little bikes being created as bespoke items in Indonesia, we thought all should be able to enjoy the ride of a Mini BMX The Venom brand was born!2013 was an exciting year for our little bikes, partnering with some of the worlds best pro riders including the Nitro Circus team many world first tricks being seen on The Mini BMX by Venom.After the huge success of our first model, we have refined the new Mini BMX by Venom to offer an truly enhanced riding experience. The new design has been tried and tested by our pro riders to be accessible to all without compromising on quality to ensure its of the high quality you expect would from the Venom brand.We have redesigned the frame geometry from the ground up to offer a higher centre of gravity, changing the balance points of the bike landing bigger tricks much easier! We have also updated the bikes gearing so you can go faster, quicker!Features:Full 4130 Chromoly FrameIntegrated Headtube9.5 X 26.5 Handle BarsCNC Alloy wheels exclusive to Venom4130 Chromoly 3 piece cranksLightweight Alloy PedalsFully sealed stainless steel wheel bearings28/12T GearingTop loaded stemThread-less ForksPair of stunt pegs includedCheck stock and price


text:
Voters determined much of Pasco County's near-term law enforcement strategies in January when they approved new property tax exemptions that reduced property tax revenue to the county by nearly $17-million in the coming fiscal year. No longer are there debates over how many deputies to add to the payroll, but rather how to best use the existing personnel. So, a question for voters to consider Aug. 26 is who is best prepared to lead the Pasco County Sheriff's Office in the face of limited resources now and in the near future.
We find many faults with incumbent Republican Sheriff Bob White's budget performance over the past four years. He drives a no-bid, high-end SUV at twice the cost of a deputy's patrol cruiser. He let scores of non-emergency civilian employees use department cars and publicly financed gasoline for commuting and personal errands. As he neared the start of his 2004 re-election campaign, he retained a human resources consultant for non-specific training and advisory roles. It cost $96,000 over four years and White rationalized it by saying the department needed, in his words, a healing. The sheriff supported Amendment 1 in January, even though it cost his department hundreds of thousands of dollars in escrow to hire new deputies if the amendment failed.
According to the county budget office, over a five-year period ending in 2007, White's department accounted for 55 percent of the property taxes in the county's general fund and the sheriff had received nearly 98 percent of his submitted budget requests from commissioners. That's not even counting the millions of dollars earmarked for patrol cars and laptop computers in Penny for Pasco funds.
Over those five years, the county population grew 20 percent and the inflation rate totaled 17 percent. Compounded, the sheriff could have expected a 41 percent funding increase. Instead, his budget grew 51 percent and, still, he complained last summer that it wasn't enough. He said he had low-balled the county and called commissioners short-sighted.
We're not convinced the department needs a new leader, but what it deserves is a better leader and we believe White, 58, has the ability to fill that role. There is evidence the sheriff finally gets it. Last year, he eliminated his civilian crime-prevention unit and transferred the positions to the more vital roles of emergency dispatcher. The voter-forced fiscal responsibility helped kill the consulting contract and White took away the take-home cars for civilians after a campaign opponent highlighted it as wasteful.
White began a citizens service unit to reduce the non-emergency workload on road deputies and he plans to rework the popular citizens academy to turn it into a training center for neighborhood crime watch patrols in order to better capitalize on volunteers. It is a sensible idea and one that none of the others in the race for sheriff have indicated is a consideration.
White's Republican opponent is retired Lt. Robert Sullivan, a 26-year veteran of the agency who left last year as commander of the vice and narcotics unit. There is much to like about Sullivan, 46. He is a well-respected lawman who came up through the ranks and worked under five sheriffs. His whistle-blowing put the spotlight on the expensive take-home car policy.
But he suggests, without documentation, as many as 42 officers are in political roles answering calls for service from sheriff acquaintances or upper middle-class neighborhoods. To meet budget demands, he said he will reallocate jobs and seek grant-funded positions. White correctly notes the department did just that in 2001 after a highly critical audit of his predecessor and the addition of 44 deputies to the payroll.
The agency doesn't need to reinvent the wheel. White, however, needs to reinvent his leadership skills. Republican voters should allow him a chance to do that in the Aug. 26 primary.
Kim Bogart, 56, (his name is on the ballot as K.S. Bogart) a police consultant and a former major and captain under Pasco Sheriffs Jim Gillum and Lee Cannon, has the knowledge and professional experience to run the Sheriff's Office. He is executive director of the Florida Corrections Accreditation Commission, and spent his early career in the city of Tampa Police Department.
Bogart is heavy on criticism of the incumbent, but gives short-shrift to concerns about his own role as a high-level commander in the two troubled administrations preceding White's. Saying you were out of the loop and doing what you were told isn't much of an accounting considering Gillum's misconduct and the Cannon administration's inability to decipher the department's own capabilities.
Still, Bogart's role studying other police agencies for the past seven years provides him a unique insight that his opponent cannot match.
The other Democrat is Jeffrey Deremer, a 15-year probation and parole officer with the Florida Department of Corrections in Pasco. Deremer likes to point he is the only Pasco native, and, at 38, the youngest candidate running for sheriff. He talks passionately about improving law enforcement in his home county, but he also offers an illogical suggestion that voters should entrust him with an 1,100-employee, $85-million agency because past supervisors-turned-sheriffs performed poorly.
Deremer simply lacks the administrative experience to run the Sheriff's Office. His answer to cost challenges is to try to get more money from convicted criminals via a new tax. Considering restitution requirements, court costs and other expenses assessed via the criminal justice system, don't expect a new crime tax to produce significant revenue for the Sheriff's Office.
Democrats seeking to nominate their strongest candidate for the November general election should choose Bogart in the Aug. 26 primary.


text:
Gentoo Linux 2008.0 released
The 2008.0 final release is out! Code-named "It's got what plants crave," this release contains numerous new features including an updated installer, improved hardware support, a complete rework of profiles, and a move to Xfce instead of GNOME on the LiveCD. LiveDVDs are not available for x86 or amd64, although they may become available in the future. The 2008.0 release also includes updated versions of many packages already available in your ebuild tree.
A big thanks goes out to our release engineering team members for their hard work over many months to turn 2008.0 into reality.
Get the new release from our "Get Gentoo!" page.
|Copyright 2001-2017 Gentoo Foundation, Inc. Questions, Comments? Contact us.


text:
The perfect tangy lemonade drink calls for fresh lemon juice. Open a homemade lemonade stand with fruity drinks that promise a pucker. These easy drink recipes include strawberry lemonade and lemonade fizz, as well as the traditional lemonade we love.
Basil LemonadeBetter Homes and Gardens
Lime juice and lemonade blend nicely with the sweet taste of fresh basil leaves in this summertime drink. Slices of lemon add a finishing touch.
LemonadeBetter Homes and Gardens
For best results, use fresh-squeezed lemon juice in this puckery-sweet drink recipe. Be sure to try the peachy version too.
Carrot LemonadeBetter Homes and Gardens
Packed with vitamin A and C, this is a great drink to have on hand. Make a double batch and store in the refrigerator up to one week.
Watermelon-Basil LemonadeBetter Homes and Gardens
Jazz up a timeless thirst-quenching drink with fresh herbs and summer fruit.
Strawberry LemonadeBetter Homes and Gardens
A favorite among kids and adults, there's nothing more refreshing on a hot afternoon than a glass of strawberry lemonade. Try the make-ahead recipe directions to prepare for potlucks and barbecues.
Coconut LemonadeBetter Homes and Gardens
Take lemonade to the tropics with a touch of coconut syrup and fresh berries. It's a refreshing summer drink for outdoor parties.
LemonadeFamily Circle
There is nothing like a pitcher of refreshing lemonade on a hot summer day. Garnish this kid-favorite recipe with lemon slices.
Fizzy Kiwi LemonadeBetter Homes and Gardens
This drink is loaded with fresh fruit, much more nutritious than soda or bottled fruit drinks. Each serving meets the daily recommendation for vitamin C.
Fresh-Squeezed LemonadeMidwest Living
Enjoy this chilled lemon, orange, and lime drink with or without alcohol.
Slime PunchParents
Make this frothy green drink recipe for a Halloween party.
Hawaiian LemonadeBetter Homes and Gardens
Serve this island-inspired adults-only alcohol-spiked blend of lemonade, apricot nectar, pineapple juice, and ginger ale at a summer cookout. For an nonalcohol version of the drink recipe, leave out the vodka.
Madeline's LemonadeBetter Homes and Gardens
Fresh berries and limes make this summer drink extra special.
Tangy Citrus LemonadeMidwest Living
We used both lemons and limes to make this chilled berry-spiked drink.
Spiced Citrus CocktailBetter Homes and Gardens
Cranberry syrup adds a pop of color and flavor to this layered citrus cocktail.
Pineapple LemonadeFamily Circle
Selzer water turns this refreshing beverage into a sparkling lemonade. Fresh pineapple, blueberries, and strawberries serve as colorful garnishes.
Blue Slime SipperBetter Homes and Gardens
The "slime" is blueberry-flavored gelatin floating in sparkling lemonade in this Halloween drink.
Mint LemonadeMidwest Living
Use fresh lemons and limes to make this crisp and refreshng cold summer drink.


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day in the lives of presidential candidates Bob Russell, Matt Santos, and Arnold Vinick, who are in Iowa trying to gain support for their campaigns. Iowa is the first state in the nation to hold their presidential caucuses, and issues affecting farmers and rural areas are the focus. The most important issue on the table is the large federal subsidies for ethanol fuel given to corn growers, which is supported by Iowa residents but seen as naked pandering by the rest of the country. Josh continues to clash with Santos over winning votes instead of proposing radical policy. Donna and Josh continue to avoid speaking about the state of their relationship.Resumen IMDb.com
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|The West Wing - S6 E13 - King Corn-spa.srt


text:
Flower Garden Banks Condition Report (2.3 MB)
Flower Garden Banks Condition Report (High Resolution - 21.4 MB)
In September 2008, the eye of Hurricane Ike passed directly over East Flower Garden Bank en route to Galveston, TX. Although this was rated a Category 2 storm according to wind speed, it's enormous size caused it to move water like a Category 4 storm.
In October 2008 sanctuary staff conducted a "quick look" assessment of the reefs. What they saw was reminiscent of the aftermath of Hurricane Rita in 2005. Some boulders of coral up to four meters across had been torn loose from the reef and tossed about, sometimes landing more than 25 feet away. Others had been toppled in place. As much as three feet of sand was scoured away from coral formations along the sand flats, then piled deeper in other areas. Several mooring buoys were also gone.
This and future assessments following Hurricane Ike are not included in the 2008 Condition Report. For more information and photos of Hurricane Ike's reef impacts, visit the 2008 Post-Ike Reef Assessment expedition page or read this summary (3.2 MB).
indicates a link leaves the site. Please view our Link Disclaimer for more information.Revised
July 31, 2017
by Sanctuaries Web Team | Contact Us | Web Site Owner: National Ocean Service
National Ocean Service | National Oceanic and Atmospheric Administration | Privacy Policy | For Employees | User Survey


text: As the world's top Cross Country runners prepare for the beginning of upcoming season, so too is the northwestern Polish city of Bydgoszcz as it prepares to host the 2013 IAAF World Cross Country Championships.The 40th edition of the Championships on 24 March 2013 will be a historic occasion for his city of 400,000 as it becomes the only city to host the event for the second time. Bydgoszcz, which sits 270 kilometres west of Warsaw, hosted the world's finest middle and long distance runners in 2010, a competition that was just the most recent in a string of major events which have made Bydgoszcz synonymous with high level competitions at both the continental and global levels.2010 witnessed an historic sweep as Kenya became the first nation to win all gold medals at stake, four individual and four team titles. The individual highlight for the east African powerhouse was delivered by Joseph Ebuya whose victory ended an 11-year individual gold medal drought for Kenyan men.Two years earlier, Bydgoszcz hosted the 12th IAAF World Junior Championships, a successful and memorable competition which witnessed one World junior record, six Area junior records, 10 championships records, and 74 national junior records.But the city's relationship with the IAAF dates back well over a decade now as the host of the first edition of the first IAAF World Youth Championships held in 1999. Those inaugural championships brought the spotlight for the first time on athletes who are now some of the sport's biggest names, including two-time Olympic champions Yelena Isinbayeva and Veronica Campbell. It was also a springboard for, among others, former World champions Jana Pittman and Ladji Doucouré. That year, the late IAAF President Primo Nebiolo was named an honourary citizen of Bydgoszcz.On the continental level, its CV goes back even further as the host of the European Junior Championships in 1979. Teenagers who won or showed well thirty years ago included a then-unknown British middle distance runner Steve Cram and West German high jumper Dietmar Mogenburg who would later become, respectively, World and Olympic champions as well as World record holders. Decathlon winner Siegfried Wentz of the former West Germany later went on to capture World silver and Olympic bronze. The women's Javelin Throw champion that year, Fatima Whitbread of Great Britain, claimed the World title eight years later. The winner in the Pentathlon, West German Sabine Everts, just three years later won the European Long Jump title before taking 1984 Olympic bronze in the Heptathlon in Los Angeles.In 2004, the city hosted the 25th Anniversary edition of the European Cup, less than two months after Poland joined the European Union. Among the highlights were wins by Swedes Stefan Holm and Christian Olsson in the High Jump and Triple Jump respectively, serving as a prelude to their Olympic victories in Athens less than two months later. Likewise Russian Yelena Slesarenko took the High Jump crown in the build-up to her Olympic triumph. There was also a sensational 14:29.11 solo run by Briton Paula Radcliffe in the 5000m.The city also hosted the fourth edition of the 4th European U23 Championships in 2003 in which Isinbayeva won one of her many titles and where Swede Carolina Kluft warmed up for her World triumph in Paris with a victory in the Long Jump.Located on the Brda and Vistula rivers, Bydgoszcz's history dates back nearly seven centuries. A northern Polish provincial capital, it's an important centre for industry, commerce and culture, and is the eighth largest city in Poland.Bob Ramsak for the IAAF


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Restore youthful radiance with the Tria Age Defying Laser, a clinically-proven anti-ageing device that works to improve signs of ageing on the entire face, including wrinkles, discolouration and texture.
Utilising the same laser technology as professional salons and clinics, the innovative device delivers beams of light deep into skin that continuously rebuild collagen beneath the surface. This natural collagen renewal process expertly smoothens and softens the appearance of fine lines and wrinkles, and raises pigmentation to the surface which is then dissipated through the skin's natural exfoliation. Youthful radiance is restored within 2 weeks.
Outperforming traditional creams and serums, the innovative device has been designed in collaboration with dermatologists and plastic surgeons for expert results. Skin is smoother, brighter and more even in tone. Clarity is enhanced for a truly younger-looking complexion.
For the ultimate anti-ageing experience, use the device for the full 8-week treatment period.
Safe to use on the forehead, cheeks and around the eyes.
Please check the stock availability notice on your item when placing your order. This item is:
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Please remember to add postal time (2-3 working days) to obtain a complete estimate of delivery to your door.
You will receive an email to confirm when your item has been sent.
You can also check the status of your order and individual items by accessing My Account details and following the prompts.
Please allow 10 working days from dispatch of your order before notifying us of any late deliveries.
It may be advisable to check with your neighbours to see if a parcel has been left with them, check any outhouses you might have where it may be left if it cannot fit through your letterbox and contact your local sorting office to see if the item has been returned to the depot as undelivered and awaiting collection.
Please see our returns policy.
Mankind Outlet
Tria Age Defying Skincare Finishing Serum
Elemis Cellular Recovery Skin Bliss Capsules (60 Capsules)
Calvin Klein
Calvin Klein Riviera Bathrobe - Charcoal
Omorovicza Gold Hydralifting Mask
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Tria Age Defying Laser
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At 540gr, these are truly the ultimate waterproof light & fast touring saddle bags. Stand alone use, or combined with any trunk bag. Perfect match with Arkel's Tailrider.Position: Rear
• 19 oz / 540 grams for the set!
• Featherweight 400 denier ripstop Nylon with TPU coating
• Waterproof roll-top design
• Reflectors on all sides for safety
• Can be paired with any Trunk Bag
• Built-in handle or optional shoulder strap
• Rolls tight for easy storage
• Dimensions per bag: 14.5" X 11" X 5.5" / 37cm X 28cm X 14cm
• Compact rolled size 15" X 4" X 2"
NOTE: Arkel's Dry-Lites are built for lightness and performance. The lifetime warranty still applies, but wear and tear and resistance to impact is less than with Arkel's heavy-grade products.
Below: Dry-Lites paired with the Arkel Tailrider sold separately.
" I had the pleasure of testing the Dry-Lites in the perfect setting. The French "Route des Grandes Alpes" from Nice to Albertville is the exact terrain and conditions these fully waterproof and featherweight bags were designed for.A full set of evening clothes, including light shoes, rain gear, warm jacket, tablet all fit in the Dry-Lites. The rest of the quick access stuff and the occasional bottle(s!) of wine, fit in the perfectly matching TailRider trunk bag. Coupling the TailRider with the Small Handlebar Bag to carry my SLR camera, was all I needed to ride the challenging route across the Alps. We stayed in small hotels along the way. On day loops, we left either the TailRider or the Dry-Lites at the hotel depending on weather. In short, the available volume combined with the feather weight of the Dry-Lites truly make them the Formula One of bike travel bags." Paul, Arkel Owner and long-time cycle tourist.
Arkel Owner Paul McKenzie cycle touring ultralight - France 2013
Related Products
7 customer reviews
Great product
If you are looking for lightweight, look no more, these are big enough for lighter touring, fairly waterproof and reasonably tough. They are not for those who take the kitchen sink, or ride through cactus, but with a bit of care and minimal gear, best choice in a pannier.
Excellent for small and light trips
Use mine for commuting. I work at a grocery store and these are great for small grocery runs. Not seeing myself giving these up!
Perfect for my needs
I couldn't be happier with these. Light, waterproof and strong enough, I used them on the Dalton Highway, a good test. Paired them with a VO Constructeur Rear Rack which is minimalist yet strong as well. I prefer the black, though I can understand where others would like to see some bright colors. The best feature for me is the ability to roll them up into a tiny package for travel.
Bikepacking Panniers
If you like the idea of bikepacking with frame bags and minimalist gear but prefer rear panniers for fit, convenience and/or extra storage, the Dry-Lites are a great choice. Sgt Peter Viol used a set on his rig during the 2015 Tour Divide: http://www.therecord.com/news-story/5739901-local-officer-faced-bears-mountain-lions-on-28-day-ride/. Even though they're definitely lightweight, they're tough and waterproof. Just be sure to pack clothing or other soft edged items inside to keep them within the handling range they were built for. A tough rear rack like the Tubus allows you to team the Dry-Lites up with an Arkel Tailrider making a perfect match.
A couple of reviewers have commented on wanting BRIGHT colours for busy roads but those of us cycling on lightly traveled dirt or gravel backroads prefer the black bags for hiding mud/dust/dirt. The easy fix for more visibility is simply to go with one large safety triangle out back (or on your back) or use several as shown in this review: https://trikeasylum.wordpress.com/stevestuff/arkel-dry-lites-pannier-evaluation/.
As for the comment about adapting Dry-Lites as front panniers, see the photo example of a cyclist on the Great Divide using Dry-Lites front and back on Flanagan's Ride of the Great Divide Day 19 Basin to Butte Riding with Lug'a and Nicoli to Butte: Lug'a used rear Dry-Lites on her bike while Nicoli had them doubled up at both ends. It might be a case of choosing a suitable front carrier than designing a new style of Dry-Lite.
Nice Panniers
I like that they can be rolled up, not in the way when not used. Great for extra room needed for clothes when riding in fast changing weather.
Write Your Own Review
Arkel Panniers - designed for cyclists, by cyclists


text:
A major planned maintenance shutdown and a furnace incident last year at the Stanlow refinery - which supplies about 15 percent of UK's transport fuel requirements - coupled with weak commodity prices hit output and refining margins.
Essar Energy, which received a possible 900-million-pound takeover offer from its largest shareholder, said third-quarter throughput at Stanlow fell 68 percent to 5.8 million barrels.
Throughput at the refinery is expected to be about 56 million barrels in the current financial year, down from the company's previous estimate of 59 million barrels.
Essar Energy, the power and oil and gas arm of privately held Essar Group, said price gross refining margins at Stanlow were a negative $2.61 per barrel during the quarter, compared with $7.22 per barrel a year earlier.
A furnace at the refinery suffered damage in November during start-up at the end of a planned shutdown, resulting in increased production of low-margin intermediary products. The company said it expects to complete furnace repairs by the second quarter of financial year 2015.
Essar Energy said it would mothball its smaller CD3 crude unit at Stanlow by October. The move would help reduce fuel oil and naphtha production and improve absolute margins while delivering cost efficiencies, the company said.
Essar Energy's shares were trading flat at 68.318 pence on the London Stock Exchange on Tuesday. They fell as much as 2.7 percent earlier in the day.


text:
By Elizabeth Sias
Isanti County News
Debra Pangerl of Rush City says anyone can make positive changes in the world.
Pangerl has written a book, "A Full Circle: Walking Alongside Maasai Women of Tanzania,"and will appear at Scout & Morgan Books in Cambridge Saturday, April 7, at 11 a.m. reading from and signing her book.
A Full Circle is a unique memoir that chronicles how Pangerl's search for her life's purpose lead her to Tanzania, over and over again, where she met Maasai girls and women.
Pangerl discovers that these women desire to change their predetermined lives of pre-pubescent marriage, genital mutilation and extreme poverty. She likewise discovers her own need to help these girls and women, in whatever way she can.
"I'm hoping to raise more awareness for the Maasai girls, and to inspire people," Pangerl said. "You really can make a difference in the world just by doing one more thing than you're doing now. Whatever it is, just follow your passion."
Pangerl grew up on a small farm in Minnesota far from Tanzania, East Africa. Following several life-changing events in her early 20s, she was adrift and unsettled.
Stumbling across an ad in the local newspaper's travel section appealing for volunteers to travel to Tanzania, she felt a call so strong that it was "deep within her soul."
She was on a plane to Tanzania a few months later.
While she was there, she met a woman named Phoebe and helped build a one-room schoolhouse. She thought it was a once-in-a-lifetime trip, but 10 years later, she was asked to go with 25 women from the U.S. and 10 women from east Africa to study women's issues.
"We were learning from women by going to their homes and going to AIDS clinics, finding out what their challenges and struggles are in their lives," Pangerl said.
It was unbelievable what the women go through in their lives."
Pangerl was particularly moved by the Maasai girls. The Maasai are one of 120 tribes in Tanzania. Semi-nomadic, they are the lowest of the social ladder.
"The women are very oppressed," she said. "Culturally, they're a very proud people, but have different beliefs than most Tanzanians. A lot of them exchange their daughters for cows, so they go into marriages when they're 12 years old. These little girls never have a chance to even dream of going to school."
The government pays for children to attend school up to sixth grade, Pangerl explained. After that, they have to have a sponsor.
On her trip in 2000, Phoebe and Pangerl started talking about what they could do to help. Phoebe suggested a project that would help these girls go to school. At the end of that trip they found a couple girls, and Phoebe would teach them in her home.
Pangerl found sponsors for four girls the first year at $350 a year each for tuition and room and board. That's how the IMAGE Project started. Today, 97 girls are sponsored and attend secondary school.
The girls sponsored through the IMAGE Project are 12 and older. Some have gone on to college, some get married, while others attend a vocational school.
They started by working in a village where they built a one-room primary school for boys and girls. The organization also helps the women implement agricultural projects to have some money to help their kids go to school.
"We created projects that are sustainable by them, empowering them to do their projects rather than telling them what to do," Pangerl said. "Education is our focus, but agriculture is also important."
"My life would never be the same had I not met these women," Pangerl said. "What these young girls overcome in their lives and the courage they have has taught me that some things I face in my life are nothing compared with what these girls go through, and yet they face them all by themselves. I want people to realize that the way other people in the world live is more similar than different, and how we can learn from each other."
A Full Circle is Pangerl's first book. For more information, visit www.DebraPangerl.com.


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Studio Series Artist Profile: Laurie Berg
Laurie Berg is a Brooklyn-based artist who works in multiple forms including dance, performance, collage, jewelry, and video. She is a 2010 Movement Research Artist-In-Residence. Laurie maintains collaborations with several dance and visual artists including Bessie McDonough-Thayer, Siri Peterson, Liliana Dirks-Goodman, and the women of Bitch Creek. Her various projects have appeared at Pieter PASD in Los Angeles, Roulette Intermedium, Movement Research at the Judson Church, Food For Thought, Danspace Project as part of PLATFORM: 2011 Body Madness – Rhythm and Humor, BRINK at Dixon Place, FACADE/FASAD, 303 Gallery, ICMC at Stony Brook University, the TANK, draftwork, AUNTS, and CATCH 35 among others. Most recently she has performed in the work of Heather Kravas, Megan Byrne, Sasha Welsh, Laura Diffenderfer, Christine Elmo and appeared in Tom Murrin's The Talking Show, at PS122, directed by Lucy Sexton. She currently co-produces AUNTS with Liliana Dirks-Goodman, and the Salon Show at Ulla's House with Sasha Welsh. Her jewelry can be seen around the necks of many NYC artists.
Laurie Berg. Movement Research @ the Judson Church (2011)
Berg's workings of The Afterlife is a collaboration with performers Bessie McDonough-Thayer, Jodi Bender, Gillian Walsh and other special guests. The Afterlife contains material located in the following limerick: the constant rotation of people and objects/the double entendre, shifting gazes of subjects/a dance with death/ a mess made of cloth/and a ritual on the face of the moon___.
Studio Series: Laurie Berg
Mar 15 & 16 at 6pm
In-Process Talks moderated by Larissa Velez-Jackson.
Studio Series receives generous support from the National Endowment for the Arts, the New York City Department of Cultural Affairs, the Foundation For Contemporary Arts, and The Puffin Foundation.


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Located someone who meets your criteria? Send a message to them or just a wink and see what comes of it. With a little luck you'll be on your way to true love.
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|The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer.
|Kolwijck, E. ; Kos, J.; Obermajer, N.; Span, P.N. ; Thomas, C.M.G. ; Massuger, L.F.A.G. ; Sweep, F.C.
|Publication year:
|European Journal of Clinical Investigation, vol. 40, iss. 7, (2010), pp. 591-599
|Publication type:
|Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/88953
|IGMD 6: Hormonal regulation
ONCOL 3: Translational research
ONCOL 5: Aetiology, screening and detection
ONCOL 3: Translational research
|Obstetrics and Gynaecology
UMCN Extern
Radiation Oncology
Laboratory of Genetic, Endocrine and Metabolic Diseases
|Journal title:
|European Journal of Clinical Investigation
|vol. 40
|iss. 7
|Page start:
|p. 591
|Page end:
|p. 599
BACKGROUND: A major step in cancer formation involves the degradation of the extracellular matrix, mediated by multiple degradative actions of (lysosomal) proteases. Extracellular release of lysosomal proteases (cathepsins) and their inhibitors has been associated with the development and progression of several types of cancer. We investigated whether cathepsins in ovarian cyst fluid (oCF) were associated with disease outcome in patients with epithelial ovarian cancer (EOC). MATERIALS AND METHODS: The levels of cathepsin B (CatB), H (CatH), L (CatL) and X (CatX) and their most abundant extracellular inhibitor cystatin C (CysC) were determined in oCF of 50 EOC patients by quantitative ELISAs. The cathepsin levels and ratios between cathepsins and CysC were related to clinicopathological parameters (Mann-Whitney U and Kruskal-Wallis tests) and survival (Cox Regression analysis). RESULTS: Median (25th-75th percentile) levels of cathepsin B, H, L, X and CysC in oCF were 97 (42-203), 18 (12-32), 61 (37-108), 20 (13-47) and 657 (501-805) ng mL(-1) respectively. Ratio of CysC/CatB was significantly lower for patients with metastatic compared with localised EOC (P = 0.025). Ratios of CysC/CatH and CysC/CatX differed significantly between histological subtypes (P = 0.012 and P = 0.035 respectively) and were significantly higher for high-grade tumours compared with low-grade tumours (P = 0.031 and P = 0.039 respectively). Neither cathepsins nor their ratios were significant predictors of survival for EOC patients. CONCLUSIONS: Ratios between CysC and cathepsins in oCF differed significantly between important clinicopathological subgroups. We believe that a complex cascade of proteolytic events, in which cathepsins play different roles, might be responsible for progression and metastasis in EOC.


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Fate of Belleair golf course draws near
By BRIAN GOFF
Article published on
Wednesday, Dec. 4, 2013
Photo by BRIAN GOFF
The kitchen inside the Belleview Biltmore Hotel is among the rooms deteriorating according to Mayor Gary Katica.
BELLEAIR Once the town of Belleair bought the Belleview Biltmore Golf Club on Indian Rocks Road 10 months ago, the actual fate of the property has been up in the air.
The town bought the facility for $3.5 million for two reasons: To remove the development rights from the property so no future owners could build condos or anything else on it and as a way of getting something out of the owners who were assessed more than $250,000 in liens because of penalties levied due to the deteriorated state of the Belleview Biltmore Hotel, an associated property.
At the time of the purchase, commissioners made no secret of the fact that they didnt want to be in the golf course business and continuing to own and operate the facility was the least desirable outcome.
With that in mind Town Manager Micah Maxwell issued what he called invitations to negotiate and invited interested parties to make presentations to the town regarding the future of the golf course. Those responding will likely offer to purchase the facility outright or offer to operate it under a long term lease with the city continuing to own it and receive some income from the operation.
Maxwell told the Commission meeting on Dec. 3 that the invitation responses will be opened on Dec. 5. Once he analyzes them, he will likely call a special meeting of the commission to discuss whatever recommendation he brings forth. Maxwell indicated it should not be too long before that meeting is called.
In a related matter Maxwell recommended to the commissioners that they consider changing some zoning regulations to make it possible for the Belleair Country Club, next store to the closed hotel, to buy a little over two acres of land of the hotel property. The club is said to want the property to be able to expand its parking lot.
Mayor Gary Katica made it clear that he was in favor of the move.
The Belleair Country Club is one of the towns largest taxpayers, he said. I think we should proceed with changing the zoning as soon as possible.
Then, focusing his attention on the hotel next door, Katica told the meeting he was astounded with the way the hotel had deteriorated over the past few months.
I went into the hotel last week and I was amazed at its deterioration, he said. In the three months since I was in there last I noticed the ceilings are coming down on the first floor. Water is dripping from the ceiling at a time when it hadnt rained in days. This is water coming down from the upper floors.
Katica was in the hotel showing reporters around after the story surfaced that the fate of the hotel was likely sealed with the owners moving ahead on development plans for the property.
Maxwell said he and other town officials have been meeting with residents of the RPD, explaining to them the proposed zoning changes which would make the development of townhouses on the hotel property possible. He said more meetings are planned next week.
Bankruptcy case in mediation
Town Attorney David Ottinger told commissioners that the case of resident Casey Jones bankruptcy has gone into mediation and a meeting was held on Nov. 15.
Jones owns the property at 1723 Cypress Ave. It is a property that has fallen in disrepair and has had fines of over $100,000 levied against it. The bank that holds the mortgage on the property had indicated foreclosure was about to take place because of delinquent payments. It was then Jones declared bankruptcy, forcing the foreclosure to be put on the back burner.
Ottinger said Jones told the mediator at the bankruptcy hearing that he would get estimates on how much it would cost to repair the property and bring it up to snuff. He also said he was negotiating with the bank to try to restructure the mortgage.
He should know whether he will get a mortgage modification in two to three weeks, said Ottinger. Then, if the answer is no, the bank will proceed with the foreclosure and take over.
When the issue first surfaced earlier this fall Ottinger said one of the options being considered was that the town move in and buy the property, fix it up then re-sell it.
Neighbors have been complaining about the effects the appearance of the house was having on their properties.
Biggert-Waters Flood Insurance
Belleair becomes the latest in a long line of Pinellas County communities to speak out against the Biggert-Water Flood Insurance Act, passed by Congress in 2012. The act essentially removes all flood insurance subsidies paid to homeowners in the U.S.
Assistant town Manager J.P. Murphy told the commission that Belleair is affected by the act.
Florida is the epicenter of the issue in the United States, and Pinellas County is the epicenter in Florida, he said.
Murphy told the commission that 84 parcels of land are affected in Belleair.
Among them are primary residences that will see their flood insurance premiums rise by 20 percent a year until the full risk of the policy is covered. That means thousands of dollars difference.
Other properties get the full hit right away, as do primary residences, which are sold or have their insurance policies lapse. All mortgaged properties must carry flood insurance.
The commission indicated it will unanimously oppose the act and call for its repeal at the next meeting on Dec. 17.
Commissioner Tom Shelly said the idea is to kill the act altogether then begin anew with an act that would not be as punishing to residents.
Article published on
Wednesday, Dec. 4, 2013
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Wednesday, Sept. 20
Is Belleair Beach ready for digital sign?
New fire station is the industry standard
Judge rules against Pinellas Suncoast Fire and Rescue District
Belleair Market gives back to community
Beach Community Food Pantry seeks donations
Friday, Sept. 15
Indian Rocks Beach stays busy with work caused by Irma
Belleair, Indian Rocks Beach budgets get through first reading
Wednesday, Aug. 30
Indian Rocks Beach Public Works moves into new building
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!When I was growing up we had salad every night for dinner. Lettuce, tomatoes and cucumbers. Now salads with more pizazz are easy to serve at home and are still great because they require little prep time. These are easy to do as well so you can make them at home for dinner or to entertain guests!
Boston Salad with Avocado and Lime Dressing
You will need:
2 medium heads of Boston lettuce
1 ripe avocado, pitted
1 bunch of scallions, very thinly sliced
1 bunch of fresh cilantro, chopped
For the dressing:
2 limes juiced
1/3 cup extra virgin olive oil
1/2 teaspoon of salt
1 teaspoon of sugar
a little black pepper to taste
1 tablespoon of whole grain mustard
Pull the lettuce leaves from the head and rinse gently under cold water, and lay on a clean towel to dry. Use a spoon to remove the flesh in 1 piece from each half of the avocado. Thinly slice the avocado flesh into thin wedges.
Whisk together all the dressing ingredients.
Arrange the lettuce leaves on a plate and top with the avocado wedges, scallion, and cilantro. Finish with a healthy drizzling of the dressing.
Fresh Corn Tomato Salad–Another delicious different salad to try!
You will need:
3 tablespoons white wine vinegar
2 teaspoons salt
freshly ground black pepper
1/4 cup virgin olive oil
6 ears of fresh corn
2 cups of grape tomatoes, halved
1 bunch of scallions, thinly sliced
8 ounces of fresh mozzarella
1 1/2 cups of fresh basil leaves
Whisk the vinegar, salt, and pepper into a small bowl. Gradually whisk in the oil, starting with a few drops and then adding the rest in a steady stream, to make a smooth dressing.
Shear off the corn kernels with a sharp knife over a bowl. Toss in the tomatoes scallions, and mozzarella. Pour the vinaigrette over the salad and toss to coat. Cover and let set for 15 minutes or up to 2 hours. Before serving tear the basil over the salad and stir.
Enjoy these fantastic salad recipes with a side of homemade bread or soup!
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Could Louisville take a second USF signee?
For the second time this fall, USF could see a signed football recruit end up playing for Big East rival Louisville.
Gerard Atkins, the tight end from Dixie Hollins who signed with USF in February, is a full NCAA qualifier, according to Dixie coach Mike Morey, but Atkins was not admitted by USF's academic committee for the fall semester.
Instead, Morey said Atkins was told he must take junior college classes this fall and if he can maintain a C average, he would be considered for January admission at USF. Morey said he's been contacted by Louisville, which has indicated it has a scholarship available and can get Atkins into school this fall. Louisville already has signed Wesley Chapel offensive lineman Kamran Joyer, who signed with the Bulls but was granted a release after academic issues put his admission to USF in jeopardy.
If a student-athlete is denied admission to a school, his national letter of intent is voided, meaning USF cannot stop him from signing anywhere he wants this fall. Morey said USF wants Atkins to attend Georgia Military College this fall -- as Dixie Hollins graduate Andre Hall did before starring at USF -- and would be able to play there on scholarship. Atkins could also take classes at Hillsborough Community College, where he could stay close to home and close to his Bulls teammates.
Morey said Atkins was in the process of verifying from USF that he has been released from his letter of intent, and only then can he talk with Louisville about playing there. Atkins' mother doesn't want to see him go to college far from home, but the chance to be in school this fall has Atkins considering Louisville as an option, Morey said.
Morey hasn't gotten a good answer as to why Atkins was denied admission to USF this fall, saying that his transcript shows better grades and test scores than previous Dixie Hollins graduates who have played for the Bulls.
Another Bulls signee who wasn't accepted, defensive tackle Khyri Thornton, has since signed with Southern Miss. In all, seven players of the 29 players who signed with USF did not make it to campus due to academic problems.
This isn't an oversigning problem -- USF isn't up against the overall limit of 85 scholarships, or the NCAA limit of 25 initial scholarships in a class.


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Open one door of opportunity and yet another door opens.
In my last post I inquired about where you are when opportunity knocks. There is an interesting thing I have observed about opportunity. It seems to me that every time I accept one opportunity, the door opens to more opportunities. And it usually does not wait for the first door to close.
Whereas if you don't take an opportunity when it is there, does it seem that you are less likely to have another opportunity soon? You have probably heard the term "shut the door and no one knocks." So what is it about opportunities that make them more plentiful for go-getters? Is it just a coincidence? I would think probably not.
Quit being too busy being busy and not visible to opportunity.
It may seem like the more you do, the more you have to do. In today's busy world it would be nice to space things out so you have time to schedule new tasks when you are ready. But realistically, people like to provide people new, exciting tasks when they see you. You are active and visible. Become the leader and take responsibility.
Increase your visibility.
Part of the reason for having subsequent opportunities that seem like they come all at once may have something to do with the fact that you became more visible with each new opportunity. People start seeing you as a leader.
You might be really busy because you are trying new things. Do you realize that when an opportunity comes to you and you take it, you may be stepping out of your comfort zone? As people see you willing to step out of your comfort zone, their impression of you can change. They see you as a person willing to accept challenges and responsibility. You have courage to try different things. You are showing your leadership ability. You are increasing your visibility that allows people to know and trust you. And when people know and trust you, they are more willing to give you opportunities.
Do not wait for the next opportunity and take too long to think about it. Consider what opportunities you are looking for so you can be prepared for them now. Develop your leadership skills so you will be ready for them. Grab the opportunity when it gets close to you. Motivate yourself. Build confidence in yourself so you are the obvious choice to take on the responsibility. Ask for the opportunity. As Milton Berle was quoted, "if opportunity doesn't knock, build a door."
"I'm not the kind of guy to knock at a door and then when the door is opened not go in." ~ William Saroyan
Consider the following quotes to motivate you about opportunities that are coming your way:
"The right man is the one who seizes the moment." ~ Johann Wolfgang Von Goethe
"Jumping at several small opportunities may get us there more quickly than waiting for one big one to come along." ~ Hugh Allen
"I was seldom able to see an opportunity until it had ceased to be one." ~ Mark Twain
"What I do know is that if one wants to get a boat ride, one must be near the river." ~ Anchee Min
"Life opens up opportunities to you, and you either take them or you stay afraid of taking them." ~ Jim Carrey
I wish you the best on accepting the next opportunity. Go ahead. Force open one door of opportunity and see what happens.


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Tuesday, September 26, 2017
Obesity and Weight Management
Maintaining weight loss
What are some things I can do to maintain my weight loss?
Unfortunately, we have limited knowledge of what behaviors are necessary for successful maintenance. The National Institute of Health (NIH) recommends that maintenance efforts be continued indefinitely. Dietary and physical activity modifications need to be incorporated and accepted as a way of life.
The National Weight Control Registry involves individuals who have lost at least 30 pounds and maintained the loss for a least a year. The successful maintainers in the Registry report making substantial changes in their eating and exercise habits to lose weight and maintain their losses. They carefully follow a reduced calorie, low-fat diet, increase levels of physical activity, and weigh themselves frequently. It is not established that these behaviors represent what is necessary for weight maintenance, but following these lifestyle changes on an ongoing basis have produced long-term weight loss maintenance.
The bottom line? No matter how you decide to cut calories, remember to keep at it, and keep moving; that should lead to successful weight maintenance.
Jaime Ackerman Foster, MPH, RD, LD
Extension Nutrition Associate
College of Education and Human Ecology
The Ohio State University


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Black Cards have confirmed that vocalist Bebe Rexha will be leaving the band. Read statements from Pete Wentz and Bebe herself below.
Black Cards' Facebook announcement:
It started out as friends. Never planned to do much of anything. I'd scribble my thoughts down and my friend sam would put them to music. In the studio next door to sams, we heard bebe and grant working on songs and the black cards collective was born. I got my friends spencer and nate involved so we could play live. We played a few shows and people started to take notice. Bebe started getting calls to write with all the producers in ny and la. Spencer and I started fucking around with people's accapellas for fun. We remixed our friends records, cobra, anjulie and gym class. Then we remixed rihanna and major lazer, then we went to #1 on hype machine. Life felt fun again. Having to get myself through a toxic cloud that was the past year of my life was important. The homies that have been a part of black cards will still be homies. I needed to feel like myself again. Good news is that I do. I appreciate everyone who has been a part of this journey and there are songs that you still will get a chance to hear and we will be coming through your city to steal your puppies and turn your brains to mush.
So bebe was writing with producers and we were hijacking other producers.New year, new beginnings. Bebe is now a solo artist. Follow her @beberexha and we have a mixtape coming out.
The black cards are dead. Long live the black cards.
Bebe Rexha wrote the following on her Facebook page:
A lot of fans have been asking me about my status in Black Cards, so I thought I'd clear the air. My depart from black cards was a mutual decision between the boys and I. I will support Pete and Spencer 100% in everything that they do. They will always be my homies. I wanna thank the fans for making this the best year EVER. I love you and you'll be hearing more from me soon. I hope you join the movement.
xoxo bebe
Despite all of this, Pete Wentz has vowed that Black Cards "is not over," and have a mixtape on the way.


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- Product Details
Some babies are ready to get going as soon as they are born. And for those little girls our Personalised Pink Bodysuit - Born to Go is the ultimate treat.
Whether it's shopping, dancing or visiting Grandma the "Born to Go" caption can be completed with any text you choose, giving one little girl the inspiration to get active before she can even walk.
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We're sure that you will be satisfied with your purchase and we also understand that sometimes you may want to return. We keep this process simple! Just contact us if you wish to return goods. Please note: personalised, made-to-order and perishable items are non-refundable.
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