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LAT2 (system L amino acid transporter 2) is composed of the subunits Slc7a8/Lat2 and Slc3a2/4F2hc. This transporter is highly expressed along the basolateral membranes of absorptive epithelia in kidney and small intestine, but is also abundant in the brain. Lat2 is an energy-independent exchanger of neutral amino acids, and was shown to transport thyroid hormones. We report in the present paper that targeted inactivation of Slc7a8 leads to increased urinary loss of small neutral amino acids. Development and growth of Slc7a8−/− mice appears normal, suggesting functional compensation of neutral amino acid transport by alternative transporters in kidney, intestine and placenta. Movement co-ordination is slightly impaired in mutant mice, although cerebellar development and structure remained inconspicuous. Circulating thyroid hormones, thyrotropin and thyroid hormone-responsive genes remained unchanged in Slc7a8−/− mice, possibly because of functional compensation by the thyroid hormone transporter Mct8 (monocarboxylate transporter 8), which is co-expressed in many cell types. The reason for the mild neurological phenotype remains unresolved.
- brain
- monocarboxylate transporter 8 (Mct8)
- system L amino acid transporter 2 (Lat2)
- 3,3′,5,5′-tetra-iodo-L-thyronine (T4)
- thyroid-stimulating hormone (TSH)
- 3,5,5′-tri-iodo-Lthyronine (T3)
Physiological studies have established that transport of amino acids across the plasma membrane requires the presence of distinct transport 'systems', because the zwitter-ionic compounds cannot cross the lipid bilayer by passive diffusion [1]. These 'systems' display broad substrate specificities and are accordingly termed neutral, basic, acidic, iminoglycine and β-amino systems [2]. Amino acid transport is not specific for intestinal and renal tubule epithelia, but is often studied in models of absorptive epithelia. Inherited disorders of amino acid transport are mostly severe and characterized by malabsorption syndromes and/or by aminoaciduria. These disorders often involve the failure of apical amino acid transport systems (e.g. Hartnup disorder) or, more rarely, the failure of basolateral transport systems, e.g. lysinuric acid intolerance [2].
The LAT2 (system L amino acid transporter 2) is composed of two polypeptides. The heavy-chain subunit CD98/4F2hc (Slc3a2) is a single-pass highly glycosylated protein, which associates through a disulfide bridge with a non-glycosylated 12-transmembrane-spanning light-chain subunit Lat2 (Slc7a8) [3]. The heavy chain is required for correct membrane localization of the complex [4]. Amino acid transport is mediated by the light-chain subunit, which is a member of the major facilitator superfamily. The complex is highly expressed along the renal proximal tubule epithelium and correlates with neutral amino acid reabsorption capacity along the nephron [5,6]. LAT2 bears broad substrate specificity, including all neutral amino acids except proline, and acts as an obligatory exchanger [5,7]. Antisense and overexpression studies in MDCK (Madin–Darby canine kidney) and in a hamster proximal tubule-derived cell line (OK cells) have indicated moderate changes of intracellular amino acid concentrations, and suggested a role in cysteine export [8,9]. The frog homologue of Lat1 was cloned as IU12, a developmentally regulated gene, mediating T3 (3,5,5′-tri-iodo-L-thyronine) and T4 (3,3′,5,5′-tetra-iodo-L-thyronine) uptake into Xenopus oocytes [10]. Human LAT2 (SLC7A8) and LAT1 (SLC7A5) also accept thyroid hormones in the Xenopus oocyte system [11]. Considering the large number of neutral amino acid transporters (Slc16a9, Slc6a15, Slc1a5, Slc6a14, Slc16a10, Slc43, Slc38, Slc7a10, Slc7a8, Slc7a5), it appears plausible that Lat2 and Lat1 have evolved to accommodate additional substrates, such as iodothyronines.
T3, as the most active form of iodothyronines, acts on nuclear receptors. Initially it was assumed that the hydrophobicity of thyroid hormones would allow passive diffusion through the lipid bilayer, despite the known zwitterionic character of the molecules [12]. The concept of facilitated diffusion of thyroid hormones was only widely adopted after the identification of patients with mutations in the most specific thyroid hormone transporter MCT8 (monocarboxylate transporter 8, SLC16A2) [13–15]. Only then was it discovered that mutations in MCT8 are the cause of Allan–Herndon–Dudley syndrome (OMIM 300523), a severe X-linked mental retardation syndrome first described in 1944 [16]. Mice deficient in Slc16a2 replicate the endocrine phenotype of SLC16A2-deficient patients, but do not suffer from severe mental retardation. Since T3 uptake into primary neurons does not completely depend on Mct8, but can be competed with the Lat-specific substrate BCH [2-aminobicyclo-(2.2.1)-heptane-2-carboxylic acid], we have suggested that co-expression of Lat2 in neurons complements inactivation of Slc16a2 in mice [17]. Later, we could demonstrate that both Mct8 and Lat2 mediate thyroid hormone uptake into cultured astrocytes [18]. In the present study, we describe for the first time the impact of Slc7a8 deficiency on amino acid and thyroid hormone metabolism in mice.
Slc7a8-deficient mice on a C57Bl/6 genetic background were obtained from Jackson Laboratory. To produce the targeted allele, a β-galactosidase/neomycin phosphotransferase II-poly A-signal cassette (geo) was inserted into exon 2 of Slc7a8 replacing part of the coding sequence of transmembrane helices 1 and 2. The following primers were used for PCR genotyping: 5′-CAAATGCCAGCTGTCCTGACCTCAC-3′, 5′-CAGACTTAGGGATGGTGACGCCTAG-3′ and 5′-GGGTGGGATTAGATAAATGCCTGCTCT-3′. Mice were fed ad libitum with standard rodent breeding chow (Sniff) and were killed at approx. 12:00 h. Animals were kept in accordance with local regulations (Landesamt für Gesundheit und Soziales Berlin #T458/09), under standard conditions (12 h light/dark cycle) in a specific pathogen-free environment in the central animal facility of the Charité, Berlin. Analysed animals were always littermates from heterozygous intercrosses in order to avoid potential genetic drift between wild-type and mutant colonies.
Western blot analysis
Frozen mouse organs were powdered under liquid nitrogen, and cytosolic and membrane extracts for analysis were prepared as described previously [18]. Protein (80 μg) was separated by SDS/PAGE (12.5% gels). After transfer on to nitrocellulose membranes, membranes were incubated with primary antibodies [anti-Mct8, 1:500 dilution (ATLAS); anti-Lat2, 1:200 dilution (ImmunoGlobe); and anti-β-actin, 1:2000 dilution (Rockland)] overnight at 4°C, and afterwards with an HRP (horseradish peroxidase)-conjugated secondary antibody. Signals were detected using Amersham ECL (enhanced chemiluminescence) Plus (GE Healthcare) and Kodak Hyperfilm Plus as described previously [17].
Tissues were fixed in 4% (w/v) paraformaldehyde overnight and stained with Dako Cytomation Systems according to the manufacturer's instructions. Tissues were incubated with the primary anti-Lat2 antibody (1:250 dilution) overnight. Nuclei were counterstained with haematoxylin. Pictures were taken with a Zeiss Axioscope 2 MOT Plus equipped with an AxioCam MRc5 and Axiovision software. Alternatively, Cy2 (carbocyanine)- and Cy3 (indocarbocyanine)-labelled secondary antibodies (Jackson ImmunoResearch) were used to stain calbindin (1:1000 dilution; Swant) and parvalbumin (1:1000 dilution; Swant), and confocal images were taken with a Leica instrument at the Neuroscience Research Center core facility at Charité-Universitätsmedizin Berlin.
qPCR (quantitative PCR)
Total RNA of powdered mouse tissue was isolated using TRIzol® (Invitrogen). cDNA was synthesized using the iScript cDNA synthesis kit (Bio-Rad) according to the manufacturer's protocol. qPCR was performed using SYBR Green from Abgene (Thermo Scientific) on an iCycler (Bio-Rad). Primers used for qPCR detection of thyroid hormone transporters have been described previously [17].
Hormone measurements
TSH (thyroid-stimulating hormone), total serum T4 and total serum T3 were measured by immunoassays as described previously [19]. Per genotype, eight to twelve male animals were analysed.
Enzymatic activity measurements
Type I-deiodinase activity was determined as described previously [19]. Liver protein (10 μg) and kidney homogenate (15 μg) were used, as well as 0.1 μM unlabelled rT3 (reverse T3). Per genotype, three to four male animals were analysed. The measurement was repeated two to four times with similar results.
Amino acid analysis
Urine was collected in metabolic cages over a period of 24 h. Urinary and serum amino acids were determined in the Interdisciplinary Endocrinological Special Laboratory of Charité-Universitätsmedizin Berlin according to a routine HPLC method after derivatization and fluorescence detection. Norleucine was added as an internal standard. Although serum amino acid values agree well with reported data from other laboratories, absolute numbers of urinary amino acid concentrations may represent an overestimate, which may be caused by crowding of chromatograms. However, methods and results vary in the literature.
Targeted inactivation of Slc7a8 in mice
Lat2 is considered an important neutral amino acid transporter in kidney and intestine [2], but its physiological role in the intact animal is not known. Insertion of a geo cassette (see the Experimental section) into exon 2 of Slc7a8 disrupted the protein (Figure 1A). Homozygous mutant animals (Slc7a8−/−) were born at the expected Mendelian frequency and were identified by PCR genotyping (Figure 1B). Slc7a8−/− mice were indistinguishable from their wild-type or Slc7a8+/− littermates with respect to body weight and length (Figure 1C). Lat2 protein was expressed in kidney, brain, pituitary, testis, spleen (Figure 1D) and small intestine (Figure 1E). The Lat2 signal along the gastrointestinal tract was entirely abolished in Slc7a8−/− tissue (Figures 1E and 1F). Immunohistochemistry suggests that the faint signal observed in liver is derived from Kupffer cells (results not shown). The protein of 38 kDa detected in liver and brain is unrelated to Lat2 as it remains in Slc7a8−/− tissue. Expression of Lat2 in kidney is restricted to the basolateral membrane of proximal tubules (Figure 2A).
Aminoaciduria in Slc7a8−/− mice
Mutation of the related transporter SLC7A7 leads to lysinuric protein intolerance in patients [20] and a similar phenotype in Slc7a7−/− mice [21]. We therefore asked whether inactivation of Slc7a8 would similarly affect urinary amino acid excretion and reflect the substrate spectrum of Lat2 in vivo. Mice were placed in metabolic cages for 24 h and urine was collected. Urinary amino acid analysis revealed aminoaciduria in Slc7a8−/− mice (Figure 2B). Glycine, serine, threonine, glutamine, leucine and valine were increased in urine from mutant animals. Interestingly, some classical L-type amino acid transporter substrates such as isoleucine or aromatic amino acids were not affected. We therefore speculated that other amino acid transporters partially compensate for the loss of Lat2 transporters. Expression of several candidate transport proteins was compared by qPCR (Figure 2C). Although Slc7a8 mRNA was virtually undetectable, a slight increase in Slc16a10 (a transporter for aromatic amino acids) was observed, which was, however, only significant at the 5% level upon one-sided Student's t test. Amino acid profiles in serum were also altered in Slc7a8−/− animals. Several small neutral amino acids were increased in serum, partly resembling the pattern in urine. The most striking difference was an increase in lysine serum levels in the mutants (Figure 2D).
Serum thyroid hormone levels are unaltered in Slc7a8−/− mice
Lat2 is clearly capable of thyroid hormone transport in vivo [18] and is expressed in tissues responsive to thyroid hormones, including brain, pituitary and kidney. Inactivation of Lat2 may thus alter tissue responses to thyroid hormone or have an impact on circulating thyroid hormone levels. We therefore determined circulating levels of the thyroid hormones T3 and T4, as well as TSH, in a group of male animals (Figure 3). Neither of the hormones was altered in Slc7a8−/− mice.
Thyroid-hormone-dependent gene activation
It is still possible that minor changes in thyroid hormone uptake into some tissues are not reflected by alterations in circulating hormone levels, but can be revealed on the level of target gene expression. We have therefore measured the activity of Dio1 (type I-deiodinase), a T3-responsive gene [22], in liver and kidney from Slc7a8−/− mice and wild-type littermates (Figures 4A and 4B). Again, no differences were observed. Impaired function of the thyroid axis is often reflected by changes in gene expression of Dio2 and Tshb in the pituitary. Again, no differences were observed by qPCR analysis, suggesting that the thyroid hormone axis functions normally in Slc7a8−/− mice.
Brain development and impaired movement co-ordination
We then probed thyroid hormone signalling in the cerebral cortex and cerebellum by qPCR. RC3 (neurogranin), Hr (hairless) and Dio3 are known thyroid-hormone-responsive genes in the brain. None of these genes were differentially expressed in Slc7a8-mutant cerebellum (Figures 5A–5C) and cerebral cortex (see Supplementary Figure S1 at http://www.BiochemJ.org/bj/439/bj4390249add.htm). Gross histology did not reveal any apparent changes in brain size, structure and expression of neurochemical markers in somatosensory cortex and hippocampus (Supplementary Figure S2 at http://www.BiochemJ.org/bj/439/bj4390249add.htm). In particular, a reduction of parvalbumin expression in cortical interneurons is known to occur in mice which have experienced postnatal hypothyroidism [23] or are expressing a dominant-negative thyroid hormone receptor α1 [24]. Parvalbumin expression is unchanged in Slc7a8−/− cerebral cortex (Supplementary Figure S2). In contrast, movement co-ordination was slightly impaired in Slc7a8−/− mice, as revealed in the rotarod assay (Figure 5D). Cerebellar histogenesis was normal as judged by Nissl staining (Figures 5E and 5F) arguing against developmental hypothyroidism. In addition, immunohistochemical staining with markers for Purkinje and stellate cells was normal in Slc7a8 mutants (Figures 5G and 5H).
The phenotype of Slc7a8−/− mice is remarkably mild. In contrast, mutations of related transporters Slc7a9 and Slc7a7 in mice cause cystinuria [25] and lysinuric protein intolerance [21]. Based on the Slc7a8/Lat2 substrate spectrum, Bröer has proposed SLC7A8 as a candidate gene for isolated cystinuria (OMIM 238200) [2]. Although we have detected aminoaciduria in the mutants, their phenotype does not support this idea; in contrast, cysteine excretion is diminished in our mutants.
Lat2 is not exclusively, but most strongly, expressed in absorptive epithelia, kidney proximal tubules, small intestine and placenta. Accordingly, aminoaciduria is observed in Slc7a8−/− mice. Interestingly, only a subset of known Lat2 substrate amino acids is affected, i.e. excluding aromatic amino acids. This finding suggests that (i) aromatic amino acid transport is fully maintained by an aromatic amino acid transporter present in kidney tubular cells, and (ii) that remaining neutral amino acid transport is partially rescued by an alternative transporter. In the kidney, it has been proposed that Lat2 co-operates with two other transport activities expressed on the basolateral membrane [26]. A unidirectional exporter is required to drive amino acid export from the proximal tubule epithelium, because Lat2, as an obligate exchanger, cannot create a net flux over the membrane. The role of Lat2 is thus to extend the substrate spectrum for export, if the substrate spectrum of the uniporter is more limited [2,27]. A good candidate for such a uniporter is Tat1/Mct10/Slc16a10, an aromatic amino acid transporter. Compatible with this idea, we have found moderate induction of Slc16a10 mRNA in kidneys of Slc7a8-mutant animals. Influx of exported aromatic amino acids may then allow the export of the whole spectrum of Lat2 substrate amino acids. Some of these amino acids are then used in turn as co-substrates for Slc7a7, the y+Lat1 transporter of basic amino acids mutated in lysinuric protein intolerance. Functional interference of Slc7a8 with basic amino acid transport is supported by increased lysine serum levels in Slc7a8 mutants. However, the mechanism cannot be inferred from the data presently available. Intestinal amino acid absorption has not been tested in these mice, since it is apparently not limiting considering normal growth and weight gain of mutants. Moreover, Lat2 has been implicated in amino acid transport across the placenta [28]. Normal frequency of Slc7a8 mutants among offspring and normal growth together argue in favour of alternative placental transporters, although we have not formally investigated this question by, for example, weighing Slc7a8−/− mouse embryos or newborn offspring from Slc7a8−/− mothers. This finding is in sharp contrast with the fetal and growth phenotype of Slc7a7−/− mice [21]. It appears likely that other neutral amino acid transporters can compensate for many Slc7a8 functions in vivo. Limiting the dietary availability of essential Lat2 substrate amino acids may help reveal a phenotype compensated in our experiments by affluent amounts of amino acids in our breeding diet.
The high abundance of Lat2 in the brain suggests some role for the protein in the brain. This notion is supported by the moderate impairment of movement co-ordination in Slc7a8 mutants revealed in the rotarod task. Bröer et al. [29] proposed a possible role for Lat2 in alanine uptake into astrocytes. Alanine was suggested as the source of ammonia in the cerebral glutamine/glutamate cycle [29], which also involves a net transfer of ammonia to neurons. In this cycle, astrocytes take up extracellular glutamate released by excitatory neurons and convert it into glutamine, which is then provided back again to neurons as a source of glutamate [30]. Inactivation of Lat2 may thus slow down the glutamine/glutamate cycle by reducing the flux of alanine. Alternatively, or in addition, Lat2 may participate in astroglial glutamine export or neuronal glutamine import, although it is currently assumed that these activities are covered by systems A and N [31]. The exceptionally high concentration of glutamine in cerebrospinal fluid would make Lat2 a good candidate for glutamine uptake into neurons. It is beyond the scope of the present study to distinguish the relative roles of systems L, N and A in the glutamine/glutamate cycle. A dedicated neurochemical study would be needed to address this issue.
Lat2 accepts thyroid hormones in vitro [10,11,32] and in vivo [18]. T3 and T4 uptake into primary Slc7a8−/− astrocytes is significantly reduced, to a level identical with uptake in the presence of BCH, a specific Lat inhibitor [18]. We have analysed thyroid hormones and thyroid-hormone-dependent gene expression in organs from Slc7a8−/− mice, because we had proposed a possible compensation of thyroid hormone transport by Lat2 in Slc16a2-deficient mice [17]. Plasma T3 levels are increased and T4 levels are decreased in Slc16a2−/y mice [33,34]. Both Mct8 and Lat2 are expressed in kidney, brain and pituitary. Our findings of normal T3, T4 and TSH levels in Slc7a8−/− mice suggest that cells determining these hormone levels depend on Mct8, but not Lat2. Thus a feature of these critical cells may be lack of co-expression of Mct8 and Lat2. Since urinary loss of thyroid hormones in Slc16a2-deficient mice may reduce T4 levels [35], we have attempted to determine urinary thyroid hormone loss in Slc7a8−/− mice by a liquid chromatography-tandem MS method [36]. Although T4 was clearly detectable, the signal was close to background and thus could not be reliably quantified. Normal activity of renal Dio1 is in contrast with elevated activity in Slc16a2−/y kidney. This finding suggests that intracellular T3 signalling is not changed in Slc7a8−/− kidney.
Normal thyroid hormone levels in the mutants are in agreement with normal (thyroid-hormone-dependent) cerebral and cerebellar development in Slc7a8 mutants. Moreover, T3-dependent gene expression is not changed. We conclude that there is no indication at the moment for insufficient thyroid hormone transport into brain cells. This could be a consequence of co-expression in neurons and astrocytes of Mct8 and Lat2 [17,18] and would be consistent with a lack of overt neurological phenotype in Slc16a2-deficient mice, which contrasts with the devastating neurological disorder in patients lacking functional MCT8. It will be interesting to test, by compound inactivation of both genes, the hypothesis that Lat2 and Mct8 compensate for each other in thyroid hormone transport into brain cells.
Doreen Braun, Eva Wirth, Franziska Wohlgemuth, Nathalie Reix and Ulrich Schweizer obtained the data; Doreen Braun, Eva Wirth, Nathalie Reix, Marc Klein, Josef Köhrle and Ulrich Schweizer analysed and interpreted the data; Annette Grüters, Josef Köhrle and Ulrich Schweizer designed the experiments; Doreen Braun, Josef Köhrle and Ulrich Schweizer drafted the paper; all authors contributed to the writing of and approved the final version of the paper.
This work was supported by the Deutsche Forschungsgemeinschaft [project numbers SFB665 TP A7-2, GK1208] and Charité-Universitätsmedizin Berlin.
Abbreviations: BCH, 2-aminobicyclo-(2.2.1)-heptane-2-carboxylic acid; Dio, deiodinase; LAT2/Lat2, system L amino acid transporter 2; MCT8/Mct8, monocarboxylate transporter 8; qPCR, quantitative PCR; T3, 3,5,5′-tri-iodo-L-thyronine; T4, 3,3′,5,5′-tetra-iodo-L-thyronine; TSH, thyroid-stimulating hormone
- © The Authors Journal compilation © 2011 Biochemical Society


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Director looking ahead as his first Sydney Festival comes up peoniesJohn Saxby
Published: January 26 2013 - 3:00AM
SOME might have described his decision to include challenging Chinese Opera as madness, but the Sydney Festival director, Lieven Bertels, emerged from Thursday night's performance of The Peony Pavilion happy with the audience's reaction and feeling good about the city's response to his debut program, which ends on Sunday.
"It's going well. The crazy Belgian didn't kill the festival or create havoc,'' said Bertels, 42, who grew up in Hasselt, on the Belgian-Dutch border. ''Hopefully I'm taking it to places it hasn't been, or places it hasn't been in a while.''
Ming Dynasty opera was just one of those places; so too a skate bowl in Dulwich Hill, parks in Middle Head and Mosman, and a renewed, government-led push into Parramatta, which had its own 10-day festival complete with a free, concert-fuelled opening night.
''I made a point of having a number of site-specific works and installations and projects because that's what a festival can do best,'' Bertels said of this year's $20 million event.
'What I've appreciated from [my] first festival is that a lot of Sydneysiders were open to new adventures,'' he said.
State government budget cuts stole the event's popular Festival First Night in the city centre. Bertels responded with a five-storey-high inflatable duck in Darling Harbour and a largely well-received three-week program that was heavy with live music, light on big names and glamour, but also free of any notable disasters.
Bertels, whose early training was in musicology and composition, came to Sydney from the Holland Festival. He is braced for more funding cuts before next year's program is announced.
''I fear there are more cuts to come, so we'll work closely with government to assess whether that is true and unavoidable and if it is, how we deal with it and our major stakeholders' expectations,'' he said.
"One of the challenges is certainly finding the balance between free and ticketed events that makes us unique. Doing away with the free events would take away some of the festival's identity as we know it."
The festival's final Saturday includes the free Symphony in the Domain concert, The Sounds of Kurbrick, and the annual Australia Day Ferrython. Beyond that the father of two said he was looking forward to a swim in the ocean and time with his family.
"We have another week of wrapping up and writing reports and making sure everyone that needs to receive thank yous receives those. It's not like you close the doors and run away after the last member of the audience has left the theatre."
Of the 350 performances in the festival program, more than 120 had sold out as of Friday, on festival figures.
"Box office is looking healthy,'' Bertels said. ''At one point it looked like we were going to miss budget by a duck's bill, but we're going to make target."
This story was found at: http://www.theage.com.au/entertainment/director-looking-ahead-as-his-first-sydney-festival-comes-up-peonies-20130125-2dc3g.html

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A Muslim women's group argued wearing the burqa is not compulsory under Islam in a forum held Wednesday in Australia.
Malaysia-based Sisters of Islam held the "Muslim Women's Rights Is Human Rights" forum at AUT University.
Sisters of Islam founder Zainah Anwar said she found the burqa "disturbing," and added it sends the message "a good Muslim woman is someone who is covered from head to toe."
Head of Islamic studies at the University of Auckland Zain Ali agreed, saying the burqa "was more a cultural requirement" than a religious one.
"The Islamic requirement is for modest dressing, but what has happened in many parts of the Muslim world is that the burqa has been accepted as a norm for that modest dressing," Ali said.
Recently a Saudi Arabian student was refused access to a public bus because she was wearing a burqa.
Read More: Burqa an affront to human dignity say Muslim women (NZ Herald News)
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Artist of the day: Elias Phoenix
Elias Phoenix appears to be a typical kid until his fingers touch the keys on a piano. Then, orchestral music rises from the piano and the 7-year-old belies his age by playing likea classically trained adult.
Elias, whose family lives in Brandon, recently entered a contest called the American Protege International Music Talent Competition, and finished second -- meaning that on Saturday, he'll get to go to New York to perform at Carnegie Hall.
For more on Elias Phoenix -- who also sings and loves rap music -- click here for Monica Bennett's profile.


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BACK FOR 2017! Grab your seats early on Saturday night.
The beautiful Missy Malone returns with her comedy and cabaret burlesque revue. Your host Abigail Collins is beyond funny - she will have you rolling round the tent. Velma Von Bon Bon was recently voted amongst the top 50 burlesque performers in the world - and you get to see her at Lechlade! Diva Hollywood was inspired by the first ever female tiger tamer Mabel Stark who performed in the USA in the 1920's. Diva will be cracking that whip and getting the audience involved! Kiki Lovechild is a 'professional idiot'! He is one of the leading cabaret clowns on the UK circuit, touring with variety and burlesque shows as well as performing in theatrical projects. Lena Mae is known for dazzling and charming audiences with her flirtatious, charismatic performances and in contrast, her darker, more challenging art pieces.
Burlesque Gallery
Burlesque Gallery
The stupendously popular Missy Malone and Friends Burlesque Revue returns.
Expect a little bit of tease and titillation and a whole lot of laughs!
The Missy Malone & Friends Burlesque Revue is a glorious theatre show, widely regarded as the best of its kind currently touring the U.K.
Each show features an array of titillating burlesque performances, comedy routines, cabaret and music!
Along with the stunning Missy, past shows have included such names as, Dirty Martini (USA), Vicky Butterfly, Frisky & Mannish, Millie Dollar, Cherry Shakewell, Leyla Rose, Cat Aclysmic and comedian Desmond O'Connor!
What the critics say:
***** – Edinburgh Guide
***** – Cotswold Life
Sassy, sleek & chic and all done in the best possible taste
The Gloucestershire Echo
you will need to beg, steal or borrow tickets!
Cotswold Style Magazine
For those who think there may be something seedy about watching burlesque, I would urge you to cast aside any preconceptions and go along to a quality performance such as that put on by Missy Malone et al.
Cotswold Life Magazine
PLEASE NOTE: This show includes nudity and naughty words. Children permitted at parent's discretion!


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WAKE UP with BWW 6/11/14 - ALW Visits Paige, Williams Chairs Alvin Ailey, PIECE OF MY HEART Meets the Press and More!
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: Radcliffe and Webber make TV appearances, Vanessa Williams oversees Alvin Ailey's Lincoln Center season kick-off, Signature's PIECE OF MY HEART meets the press and Jim Parsons stops by our SAG series!
- Set your DVR! THE CRIPPLE OF INISHMAAN's Daniel Radcliffe will appear on THE VIEW this morning! Plus, Andrew Lloyd Webber visits THE ELAINE PAIGE SHOW tonight (more here)...
- "A Good Read" series continues at Joe's Pub tonight with John Cameron Mitchell and Denis O'Hare performing adaptations of works by Vladimir Nabokov.
- Vanessa Williams is the Honorary Chair of Alvin Ailey's 2014 Lincoln Center season workshop performance and gala benefit this evening!
- The cast of Signature Theatre's PIECE OF MY HEART meets the press today, so be sure to check back for photos and video!
- Our SAG Foundation Conversations Series continues with Jim Parsons tonight! Stay tuned for Richard Ridge's interview...
- BUYER & CELLAR Barrett Foa-Led BUYER & CELLAR to Celebrate 400th Performance Tomorrow" target="_blank">celebrates its 400th performance off-Broadway tonight!
- And finally, tickets go on sale today for YOU CAN'T TAKE IT WITH YOU, starring James Earl Jones!
- DISGRACED, starring Hari Dhillon, Gretchen Mol, Karen Pittman and Josh Radnor, will open on Broadway in October!
- MOTHERS AND SONS, led by Tyne Daly, will close June 22nd.
- Next Tuesday, Jessie Fisher will take over the role of 'Girl' in ONCE on Broadway.
- This year's A RAISIN IN THE SUN revival has recouped its investment!
- Can't wait for the HEDWIG cast album? Well, neither could anyone else! The digital version "hits shelves" early tomorrow, June 12!
- Speaking of cast albums, HEATHERS: THE MUSICAL will celebrate its recording release with 'A Very HEATHERS Prom' on June 18th.
- IF/THEN's Idina Menzel will perform the National Anthem at the Macy's 4th of July Fireworks Kickoff!
- Audra McDonald responded to an open letter in TIME about her Tonys acceptance speech, in which she thanked her parents for not putting her on medication...
- Hugh Jackman is already prepping for his next role as Blackbeard in the movie PAN!
- Across the pond, we got a first look at Carey Mulligan, Bill Nighy and more in SKYLIGHT at Wyndham's. Plus, BWW got the inside scoop on MEMPHIS's arrival to the West End!
Broadway Weather Forecast: Come the wild, wild weather, come the wind, come the rain... Scattered showers with a high of 69 degrees.
Quote of the Day: Lord Andrew Lloyd Webber speaks on failure...
What strikes me is that there's a very fine line between success and failure. Just one ingredient can make the difference.
-- Andrew Lloyd Webber (via BrainyQuote)
What we're listening to: Sierra Boggess, Jeremy Jordan and more, featured on Michael Mott's WHERE THE SKY ENDS album, out June 17th!
And finally, a Happy Birthday shout-out to Gene Wilder, who turns 81 today!
Wilder last starred on Broadway in Luv in 1964, as well as The White House, One Flew Over the Cuckoo's Nest, Mother Courage and Her Children and The Complaisant Lover. The stage adaptation of Young Frankenstein is based on his original story and screenplay. Among Wilder's many films are the TV movie version of Death of a Salesman, Bonnie and Clyde, The Producers, Willy Wonka & the Chocolate Factory, Rhinoceros, Blazing Saddles, The Little Prince, The Adventure of Sherlock Holmes' Smarter Brother, The Frisco Kid, Hanky Panky, Funny About Love, and the TV series Something Wilder, which aired in the mid-'90s.
See you bright and early tomorrow, BroadwayWorld!


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I was told to use Sunscreen but don't remember exactly when she said it was ok. Please help me out. I need answers and advise. I was also told that i should have a microdermabrasion done next week. BTW i suffer from acne. And oh yes i woke up this morning with some whiteheads. Is that normal?
Would I be able to use the Spray Neutrogena 70 SpF Sunscreen on my face the day AFTER my Ultra Jessner Chemical Peel?
Doctor Answers 3
Melarase creams and Jessner peels
DR. Karamanoukian
Los Angeles
Learn more: http://www.surgery90210.com/cosmetic-dermatology/95/chemical-peels.aspx
Sunscreen After Jessner Peel
Thank you for your question. I would recommend using a sunscreen with SPF 30 with zinc. Depending on what your skin is like after one week and how many layers were applied, I would wait and not rush the microdermabrasion, which will be helpful to exfoliate the dead skin cells. Sometimes acne prone skin can break out after trauma to the skin such as peels. I hope this helps.
Sunscreen after Peel
Do not us sunscreen until the flaking ends. These light peels have much to offer if used with a Retin A and Hydroquinone cream. This continues the exfoliation, prevents pigment significantly, and is very acceptable to most skin types, There are many plans and regimens for this mixture and prices vary from $70 for 4 months to over $600 for 3 months. Be cautious and shop around for a generic mixture that works. Many offices now carry the favorably priced generics. My Best, Dr C
Learn more: http://www.gcommonsmdplasticsurgery.com
You might also like...
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


text: Schedule a Campus Visit Today Regis College A Liberal Arts, Sciences & Pre-professional, Residential College Regis College offers liberal arts, sciences and pre-professional degrees and programs for traditional-age high school graduates and transfer students. Rueckert-Hartman College for Health Professions Degree & Certificate Programs for Careers in the Health Professions Rueckert-Hartman College for Health Professions offers bachelor's, master's and doctoral degrees and certificate programs, designed to prepare students for exciting careers in a variety of health professions. College of Contemporary Liberal Studies The College of Contemporary Liberal Studies is a leader in adult education with accredited bachelor's and master's degrees and certificate programs that prepare you for success in a competitive marketplace. College of Computer & Information Sciences Education for Careers in Computer and Information Science The College of Computer & Information Sciences has aspirations greater than other programs. Our students learn more than technical skills; they study the impact of technology in our digital world.


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New Account Management Tools Improve Advisor Efficiency and Client Experience; Bundled Suite Reduces Advisor Costs by 50 Percent Account View, LPL Financial Mobile and Streamlined Office Tools Reflect Overall Technology Focus; Enhanced Trading & Rebalancing Platform Also Launches SAN DIEGO, Aug. 19, 2013 (GLOBE NEWSWIRE) -- LPL Financial LLC, the nation's largest independent broker-dealer, a leading RIA custodian and a wholly owned subsidiary of LPL Financial Holdings Inc. (Nasdaq:LPLA), today announced a set of enhanced technology offerings and new mobile capabilities for financial advisors and their clients, designed to simplify account management; improve practice efficiency and scalability; and enhance the client experience. The company has also bundled its main set of online tools, resulting in up to a 50 percent cost savings for many of its advisors. The revamped Account View and Streamlined Office offerings, as well as the new LPL Financial Mobile application, are an update to the current online offerings for both advisors and their clients. They include a suite of mobility products offering "anywhere access" to account information that is designed to help advisors and clients to make more informed decisions. LPL Financial also announced that its main set of online tools, including BranchNet, iDoc (document storage), Account View, eSignature, Remote Deposit, Compliance Workbench and email will be made available in a bundled Core Technology pricing plan that eliminates more than 50 percent of technology costs to advisors and institutions. Advisors attending this week's annual focus13 conference in San Diego have a chance to demo the new online offerings and solutions and interact with LPL Financial's technology team at a first-of-its-kind, 20,000-square-foot LPL Financial "Digital Town Square." In a separate but related technology announcement, LPL Financial also introduced its new Enhanced Trading & Rebalancing (ET&R) platform, which enables advisors to simultaneously manage trading activity across multiple client account portfolios.
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Chayote and Goat Cheese Casserole, a Low Carb Holiday Party Recipe
Posted on Dec 26 2012 at 02:36:33 PM in Food & Drink
If you want to liven up your holiday party try one of my favorite casseroles. While most of your guests may never heard of Chayote before they will never forget how great it tastes. A common theme at all holiday parties is to bring a new and unique dish that will amaze and please your guests. Once you have used Chayote squash and have discovered its great ability to absorb the flavors of the ingredients it is combined with to present a new and unique taste with each dish you will find a new place in your menus for it.
Chayote is also called mirliton, vegetable pear and other names in other countries, such as guisquil in Guatemala, where I first learned to use this squash. It is a relatively flavorless fruit, generally used as a vegetable. Similar to zucchini, its lack of specific flavor makes it an excellent choice to mix with other more flavorful ingredients. It is excellent as a side dish, and can even be made into a dessert. This is one very savory way I like making this into a side dish for my family.
Chayote and Goat Cheese Casserole
3 chayote squash, halved, cored, peeled and sliced thinly
4 ounces mild goat cheese
1/4 medium onion, thinly sliced
2 teaspoons green peppercorns in brine
2 tablespoons flour
1 cup milk
1/2 cup sour cream
1 teaspoon salt
1/4 teaspoon ground white pepper
Preheat oven to 375 degrees. Butter or spray with cooking spray an 8 inch square or 7 x 11 inch casserole dish. Place half the squash slices into the bottom of the pan, evenly. Sprinkle on half the onion slices, then one tablespoon of the flour, 1 teaspoon of the green peppercorns, drained, and half the goat cheese, crumbled. Place the rest of the chayote slices evenly over the first layer, repeating with the rest of the flour, onion, peppercorns and goat cheese.
In a bowl, combine the milk and sour cream with a whisk. Whisk in the salt and white pepper. Pour over the casserole. Cover the casserole with foil and bake for 30 minutes. Remove the foil and bake for 45 minutes more, until the squash is tender. Makes 6 servings.
Chayote squash grow on a vine. They are easily grown by planting the entire fruit, which will need a support for the vine to climb. It is from the cucurbita family as are pumpkins, gourds and other squash. Grow your own and have a bounty of this lesser used fruit for your family and friends. A wonderful filler food, it can be added to soups, stews, or mixed with potatoes in a dish or casserole. The squash may also be used in place of potatoes in your favorite scalloped potato dish, reducing the high carb load of the potatoes.
About The Author
My name is Chris Rawstern and I have been on a cooking and baking journey for 42 years. Many people have asked what A Harmony of Flavors means. Have you ever had a meal where the visual presentation was stunning, the smells were incredible, the taste was so remarkable that you ate slowly savoring every bite, wishing the experience would never end? Then you have experienced what a truly harmonious meal can be like.
My passion is to teach people how to create a Harmony of Flavors with their cooking, and help pass along my love and joy of food, both simple and exotic, plain or fancy. I continue my journey in ethnic and domestic cuisines, trying new things. I would love to hear from you, to help me continue my journey to explore diverse culinary experiences and hopefully to start you on a journey of your own.
Visit my Web site http://www.aharmonyofflavors.com my Blog at http://www.aharmonyofflavors.blogspot.com
my Marketplace at http://www.a-harmony-of-flavors-marketplace.com or Facebook page A Harmony of Flavors. I share a recipe or tip each day to the fans that have liked my site. I hope to see you there soon.


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Rebecca M Maertens
Affiliation: Health Canada
Country: Canada
Detail Information
- A global toxicogenomic analysis investigating the mechanistic differences between tobacco and marijuana smoke condensates in vitroRebecca M Maertens
Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON, Canada
Toxicology 308:60-73. 2013..This study shows that in general MSC impacts many of the same molecular processes as TSC. However, subtle pathway differences can provide insight into the differential toxicities of the two complex mixtures...
- Mutagenicity of smoke condensates from Canadian cigarettes with different design featuresNemanja Mladjenovic
Science Division, Office of Research and Surveillance, Controlled Substances and Tobacco Directorate, Health Canada, 150 Tunney s Pasture DRWY, Ottawa, Ontario K1A 0K9, Canada
Mutagenesis 29:7-15. 2014..Nevertheless, since the study did not attempt to evaluate the impact of the cigarette designs on human health at the individual or population level, the super slim cigarettes cannot be considered 'reduced-harm' cigarettes. ..
- Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full-flavor, blonde, and light productsCarole L Yauk
Environmental Health Science and Research Bureau, Health Canada, Ottawa, Ontario, Canada
Environ Mol Mutagen 53:281-96. 2012....
- The genotoxicity of mainstream and sidestream marijuana and tobacco smoke condensatesRebecca M Maertens
Research and Radiation Protection Directorate and Tobacco and Drugs Directorate, Health Canada, Ottawa, ON, Canada K1A 0K9
Chem Res Toxicol 22:1406-14. 2009..In addition, when corrected for total particulate matter yield, little difference was observed in the mutagenic activity of samples smoked under the extreme vs the standard regime for both tobacco and marijuana condensates...


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Harley E. Flack(Spring 1995)
Richard H. Gallagher(Spring 1995)
Allen Zweibel(Spring 1995)
Linda Phillips-Palo(Fall 1995)
Craig Cirbus(Fall 1995)
Lori Wiener (Winter 1996)
It's a parent's worst nightmare. But for nearly 8,800 American youngsters and their families, it is reality. Though the number of infants born in the U.S. with the HIV virus has leveled off, 1995 federal data indicate that AIDS has become the leading cause of death among all Americans aged 25 to 44. For children infected with the virus, the pain of isolation can be especially intense. Nobody wants to play with you when you have AIDS, nobody wants to touch you, nobody wants to be your friend.
Unless your friend is Lori Wiener, B.S. '77.
As coordinator of the Pediatric HIV Psychosocial Support Program at the National Cancer Institute in Bethesda, Md., Wiener, who earned her UB degree in social work, has devoted her career to children who have the AIDS virus. A parent herself, she has cared for more than 475 kids and their parents who must look death in the eye as they battle an illness with no cure and no easy answers.
Despite the sad nature of her work, Wiener is not depressed. Early on in her career, she found herself curling up in bed, not wanting to listen to anyone's problems, not even the ordinary concerns of her friends. But "I decided to give myself time," she explains. And a few months of psychotherapy. Both made a difference, says Wiener, who also holds an M.S.W. and Ph.D. from New York University.
Having overcome this initial hurdle, Wiener was able to embark on a lifelong commitment to caring for HIV-positive families. After 13 years, she still is careful to distinguish between sadness and depression, as these terms apply to her work.
"I personally do not find my work depressing, but it is very sad work," she says. "If you're sad in this line of work, it's appropriate.
"I have been moved by the love, caring and wisdom provided by these families. If my work has taught me anything, it has taught me about life, death, courage, compassion, resilience and a spiritual peace."
Conveying these lessons to Wiener over the years have been kids who have wisdom beyond their tender years, a depth to their outlook on life, which is expressed through poetry, drawings, essays and other therapeutic venues.
From an eight-year-old came these compelling lines: "Friends and family are important, especially when they have a deadly disease. When I have a new friend and he or she finds out I have AIDS and they do not know a lot about it, I will help them understand. My life is fun because I have a big sister who understands a lot. It is also fun because I have friends who will play with me a lot. I have two very special friends. One is Lori."
Wiener has compiled the writings and drawings of her patients into a book, Be A Friend: Children Who Live With HIV Speak, which lends a personal perspective to the disease. "All the kids' voices are direct, vivid and thought-provoking," said a Washington Post review. "(The) book speaks to everyone, child and adult, infected or not, about fear, loneliness and hope."
A native of Long Island, Wiener returned to the metropolitan New York area following her graduation from UB. From 1981 to 1985, she maintained a private practice in New York City. In February 1982, she accepted a position at Memorial Sloan-Kettering Cancer Center in Manhattan.
Just a few months after she began working in a 42-bed medical oncology unit at Sloan-Kettering, Wiener was approached by the hospital's chief of dermatology to help him deal with an increasing number of gay men diagnosed with Kaposi's sarcoma, a form of skin cancer commonly associated with AIDS.
Because a majority of the patients she treated privately were homosexual, Wiener stepped easily into her new assignment. By 1984, she was working exclusively with AIDS patients.
In the midst of her work at NYU and Sloan-Kettering, Wiener's husband accepted a job in Annapolis, Md., prompting the family's move there. She joined the National Cancer Institute at the National Institutes of Health (NIH), working with the institute's chief of pediatrics to incorporate HIV patients into the existing oncology unit. They accepted their first HIV-infected child in December 1986.
Wiener works with both parents and children to help them cope with the fear, pain and guilt of AIDS. Parents are encouraged to make a videotape to leave their children after they have died.
"I try and help them differentiate between cause and intent. It was never their intent to infect their kids," she explains.
And it is never anyone's intent to have AIDS. But for those who must face this frightening reality, it is people like Wiener who make what are often the final months more fulfilling.
The losses are many. The rewards, though, are what keep Lori Wiener moving and motivated.
"With every loss, there have been many more gains," she says. "I can tell 100 stories of exquisite human moments for every sad one. For me, this work is incredibly intense, profound, existentially seductive and sad. There is a fine line between being sad and being depressed. I am often sad. But I have not been depressed. When that day comes, I will take a break."
Diane Zwirecki, a Buffalo-based freelance writer, is assistant director of public relations at Sisters of Charity Hospital.


text: The other day on a local TV station, an air conditioner repair man was quoted as saying "I am more busy than ever due to the heat wave". I realize that most people would probably say "I am busier than ever", but I was wanting to know if "more busy" is gramatically correct, also. My wife says it is incorrect, but my thinking is that if 'less busy' is gramatically correct, shouldn't 'more busy' be ok, too? We all realize that 'more busier' is gramatically incorrect. Thanks in advance for your assistance in clarifying this issue for me.


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An effective and easy-to-use driver updater
Falco Cross is a 3d OpenGL game.
This is a Physics and strategy game where your task is to make sure the Satellite lands correctly in the platform
When an exciting excursion goes terribly wrong, Jake, a marine geologist, finds himself on a journey of survival in this adventurous Match 3 game
Bristlies is a great physics-based puzzle game, your goal is to help Bristlies to get into boxes of the same color. Cut ropes and use interactive objects to solve the puzzles. See more detailed instructions in the game.
Play as the intrepid Bret Airborne and help Doctor Altus to fight his evil twin brother and his minions in a colorful steampunk world filled with puzzles, duels, and challenging single-player campaigns with player-selected levels of difficulty


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Chargers' line adapts to life without McNeill
Published: July 28th, 2010 | Tags: Brandyn Dombrowski, Jerome Clary, Marcus McNeill, Norv Turner, San Diego Chargers, Tra Thomas
What if LT Marcus McNeill and the Chargers don't reach some sort of contract agreement to protect QB Phillip Rivers' backside?
Coach Norv Turner told NFL Network on Tuesday that the Bolts first will look in-house for a replacement, turning to second-year lineman Brandyn Dombrowski. Just in case, the club also added veteran free-agent LT Tra Thomas last month.
Dombrowski played in every game last season, and he started at right tackle after Jerome Clary went on the IR. Turner said Dombrowski is a good fit at left tackle.
Clary told the North County Times that the line is coping fairly well.
"We've got Kris Dielman at left guard, which makes us all rest a little easier," Clary said. "He's one of the best at his position, and whether Tra or Brandyn or someone else lines up at left tackle, Kris will make sure he's ready to play at a high level. He takes his work very seriously, and he'll make sure the job gets done on that side."


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Skip to comments.Hugo Chavez's hostility alarming to South Florida's Venezuelan Jews
Posted on 09/17/2006 7:17:35 AM PDT by dennisw
President Hugo Chavez's early friendship with a Holocaust denier was the first jolt.
Venezula has grown hostile to its dwindling Jewish community. Chavez's fierce criticism of Israel, repeated on recent trips to China and Syria So is the 2004 state police raid of a Jewish elementary school in Caracas.
Most troubling is Chavez's close alliance with Iran's President Mahmoud Ahmadinejad, who has called for Israel's destruction.
"I have Jewish friends in Caracas wondering if they should remove yarmulkas when they go out in the street," said Victor Amram, of Boca Raton. "Never in our lives did we imagine Jews would think that way in Venezuela."
Amram, 60, was head of the Zionist Federation of Venezuela 1998 to 1999. He was also second in command in the Policia Tecnica Judicial, Venezuela's investigative law enforcement agency. In May 1999, his Chavez-appointed boss accused him of "Jewifying" the agency's store, which sold clothes and furniture, by stocking it with merchandise from vendors who happened to be Jewish, Amram said.
Amram already had planned to leave Venezuela because of its civil instability and corruption. He retired later that year and in 2000 moved to Florida, where he owns a security company.
Roughly 25 percent of Venezuela's 30,000 Jews have left for South Florida since Chavez was elected in 1998, according to the American Jewish Committee. Most fled a rising tide of crime, kidnappings and economic uncertainty, including government encroachments on private property, that sparked a general exodus of middle-class Venezuelans.
Norberto Ceresole, the late Argentinian left-wing thinker who denied the Holocaust, had a brief stint as Chavez's adviser in the early days of the populist leader's presidency.
In a 2005 Christmas radio broadcast, Chavez referred to the Jews as "descendants of those who crucified Christ" and have "taken over the riches of the world."
(Excerpt) Read more at sun-sentinel.com ...
Venezuela's President Hugo Chavez, right, and Iranian President Mahmoud Ahmadinejad, hug each other after Chavez was awarded the 1st grade order of the Islamic Republic of Iran during a ceremony in Tehran university in Tehran, Iran, in this Sunday, July 30, 2006 file photo. Ahmadinejad will make his first visit to Venezuela on Sunday, Sept. 17, 2006, strengthening ties with a country that has become the leading defender of Iran's nuclear ambitions on the world stage. (AP Photo/Hasan Sarbakhshian/FILE)
Yah,as if Chavez gives a rat's hindquarters about Christ or his teachings.
...because they still have family there?
Would you be able to answer why do Irish in Boston fear a return of the troubles in Northern Ireland?
Actually you should fear Chavez in Venezuela the Iran-Venezuela alliance is a strategic threat to USA and our oil supplies. As far as Hugo Chavez being anti Semitic and Amadinejad wanting to destroy Israel. This translates into the USA also being in their gun sights
Are they South Floridians or Venezuelans? If they are Floridians why would they fear Chavez?
MY point was the headline is totally misleading.
No. Why would they?
I agree that Chavez is nuts and presents a clear danger with his power. I was pointing out that this is not really news. It's a made up story with a misleading headline.
Are you for a unitied and free Ireland?
I never knew Hugo Chavez was so anti Semitic. This makes him more of a menace to USA because it cements his alliance with Amadinejad. Does this make any sense? And why Chavez's anti Semiticism can affect you?
I really have no opinion on that.
But you have an opinion about this. Rokey-dokey.
Actually my point was the misleading headline.
Does Ireland have a dictator? Are they persecuting displaced Irish here in the U.S?
I ask again, why would people living in south Florida feel threatened by Chavez? Are they not U.S. citizens protected by the U.S?
I'd think they regard themselves as Venezuelans living in exile, who still care about their homeland, as well as the Jewish people who remain there, many of whom they no doubt know or are even related.
"Ethnic" politics are a reality in this country, and have been for over 150 years (at least).
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.


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How Can Colleges Embrace Different Faiths?
Eboo Patel, a speaker and consultant, has made it his mission to get colleges nationwide to lead smarter conversations about religious pluralism.
Goldie Blumenstyk, a Chronicle writer, describes Mr. Patel's unique style—and discusses the merits of separating discussions about faith from political activism.
Read Goldie's story: Eboo Patel Has a Dream
Download this recording: MP3 Version


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May 7 2013
Featured groups for first two rounds
PONTE VEDRA BEACH, Fla. -- Here's a look at some of the featured groups for the first two rounds of THE PLAYERS Championship this week (click here for tee times):
Tiger Woods/Matt Kuchar/Brandt Snedeker -- Kuchar is the defending champ, while Woods and Snedeker haven't fared as well in this event in recent years. Watch this group live in Friday's second round at 8:39 a.m. ET on PGATOUR.COM's Follow A Group feature
Phil Mickelson/Webb Simpson/Justin Rose -- Wonder if last year's Ryder Cup singles match, with Rose beating Mickelson, will come up in conversation?
Adam Scott/Rory McIlroy/Steve Stricker --Scott is making his first start since winning the Masters. Only one player has ever won the Masters and THE PLAYERS in the same year (Tiger Woods, 2001). Watch this group live inThursday's first round at 8:39 a.m. ET on PGATOUR.COM's Follow A Group feature
Ian Poulter/Nick Watney/Lee Westwood -- Did you catch Poulter's cover photo on Sports Illustrated's special PLAYERS Championship preview? Very dapper.
Sergio Garcia/Luke Donald/K.J. Choi -- Choi and Garcia are previous winners of THE PLAYERS; Donald has finished sixth or better last two years. Watch this group live in Thursday's first round at 1:39 p.m. ET on PGATOUR.COM's Follow A Group feature
Rickie Fowler/Hunter Mahan/Jim Furyk -- Furyk and Fowler ran into each other at a local sushi/Thai restaurant on Monday evening. Coincidence?
Billy Horschel/Dustin Johnson/Ernie Els -- Horschel lives in the area, but that hasn't always been a big advantage at this tournament. Watch this group live in Friday's second round at 1:39 p.m. ET on PGATOUR.COM's Follow A Group feature
Graeme McDowell/Keegan Bradley/Bubba Watson -- McDowell won three weeks ago in Hilton Head, while the two Americans are still trying to find the winner's circle in 2013.
For more about Follow A Group and other live streaming on PGATOUR.COM during PLAYERS week, click here


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Energy Policy: Lots of Heat, No Light
May 2, 2012
The president has repeatedly asserted that the United States cannot possibly produce the amount of oil that it consumes. To support this claim, he points to the relatively small level of proven reserves within the United States' borders, and emphasizes that this small reserve could not possibly fulfill America's enormous consumption. But this misleads the American public because it disguises the meaning of "proven reserves" and misleads citizens to believe that there remain no undiscovered oil assets, says Irwin Stelzer, director of economic policy studies at the Hudson Institute.
- In 2000 it was estimated that reserves that fit the Obama definition totaled some 20 billion barrels.
- In the 10 years after 2000, oil producers in the United States produced approximately 20 billion barrels, and yet the end-decade estimate of proven reserves was still 20 billion barrels.
- Furthermore, an element of this misleading claim on the part of the president is that it fails to account for resources that, while inaccessible, will likely be made so through technological advancements (see the two trillion estimated barrels in shale and sand).
The president nevertheless exploits the fact that America is responsible for 20 percent of global oil consumption annually but produces only 2 percent of global oil production to justify alternative sources of energy. This is deceptive, and offers only an artificial rationale for the development of alternative sources.
Furthermore, none of these alternative sources to which enormous amounts of taxpayer funding are allocated will likely prove able to fulfill future energy demands.
- Nuclear power producers are harangued by regulators and safety requirements that change constantly and hamper efforts to produce efficiently.
- Solar power has proven in many cases to be unable to operate in hot climates, and even then the electricity that is produced is enormously expensive.
- Wind farms also face numerous technical obstacles, and even then, they require substantial investment in transmission lines and infrastructure.
- Finally, many of these are too expensive to remain sustainable without government support, especially in light of the natural gas renaissance.
The president's plan for an "all of the above" approach to energy policy is disingenuous, and seeks to subvert the enormous benefits of domestic oil production.
Source: Irwin Stelzer, "Energy Policy: Lots of Heat, No Light," Hudson Institute, May 2012.
For text:
Browse more articles on Environment Issues


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Get a FREE Arby's Turkey Roasters sandwich on Thursday, September 6th from 11 am – 1 pm! No purchase or coupon required! Choose from Turkey Classic, Turkey 'n Cheddar Classic, or Grand Turkey Club. Limit 1 sandwich per person at participating locations.
If I can actually get there, I'll be trying the Grand Turkey Club! What about you? Click HERE for more information.


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12 "Therefore you shall speak to them this word: 'Thus says the Lord God of Israel: "Every bottle shall be filled with wine." '
"And they will say to you, 'Do we not certainly know that every bottle will be filled with wine?'
13 "Then you shall say to them, 'Thus says the Lord: "Behold, I will fill all the inhabitants of this land—even the kings who sit on David's throne, the priests, the prophets, and all the inhabitants of Jerusalem—iwith drunkenness! 14 And jI will dash them 8one against another, even the fathers and the sons together," says the Lord. "I will not pity nor spare nor have mercy, but will destroy them." ' "


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> Meanwhile, it might be nice to have a syntax to hard wire specific > library options, especially if available as an [=/path] option to the > --with-<feature> directives. There may be occasions to do much more > intricate specification of configuration (such as we were doing with our > custom SSL builds). You'd have to take this up with Peter Eisentraut. I already had this argument with him and lost. -- -- Josh Berkus PostgreSQL Experts Inc. http://www.pgexperts.com
Next: From: Chris Ruprecht Date: 2010-06-09 19:03:26 Subject: 9.0Beta2 Build on Mac (64 bit) of pg_upgrade fails with duplicate symbols Previous: From: Glen Barber Date: 2010-06-09 12:39:36 Subject: Re: Misplaced pg_upgrade_support.so ?


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Umm, on The Song Remains the Same the live version of Dazed and Confused is like 34 minutes. That's the longest I've heard, but I'm sure some crazy metal band from Norway has a longer one...
Type: Posts; User: Kristi920
Umm, on The Song Remains the Same the live version of Dazed and Confused is like 34 minutes. That's the longest I've heard, but I'm sure some crazy metal band from Norway has a longer one...
Since I'm total sony fangirl I'll be going for the 3 when I have enough money.
Probably after I get Medal of Honor and Ace Combat fore the PSP.
Thats cool. It seems like most you who have thinks it dumb though lol
(thanks for actually replying, I'm usually a thread killer; self esteem + 6)
Let me rephrase:
I'm not into myspace AT ALL
I was just curious to see how many people had one and how many people were "addicts"
Do a lot of you people have a myspace?
I'm not really into it, but I was curious to see how many others were.
Are there any hardcore users? Like, who spend every spare second updating their page,...
I think some of them are kinda creepy, but I can't remember which ones... Probably Moses or something...
How did you roll the joint with scissors in your hand? :confused:
^^ Band Name Calculator ^^
I got "The Dandriff Batch",and I like it.
Well, at least they labeled it as "Ghetto Fighting"
I saw "Rod Stewart: In Concert" in the movie theather last week. It was simulcast from New York or something...
I won the tickets from a radio station. Got his new CD too; I'm sending it to my...
he's a pro skater, and pretty awesome...
(FC= Fan club, sorry I was all lazy when I typed)
On topic - I'm in the Eric Koston FC
When I was little I jammed my leg into the protruding end of a metal bed frame. Took a good chuck outta me about the size of a dime. I still have the scar.
Use this fat calculator to check yourself. Just enter Height and Weight.
Depends on how tall you are.
I'm fine sleeping on them, but then again they're not too big.
Prader-Willi Syndrome
He really isn't that bad. I've known dogs who weigh more than that.
In a different sense, yes.
He's got nice ankles for the fattest teen in Britain.
I just had to read that for my AP English class.
Yea, pretty cool. BTW, nice bed! ;)
The Electric Kool Aid Acid Test - Tom Wolfe


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The race to replace Rep. Gabrielle Giffords in Congress has been hijacked by Social Security and Medicare.
A stagnant economy, border security and high gas prices are riding in the back seat in the Congressional District 8 special election pitting Democrat Ron Barber against Republican Jesse Kelly.
The candidates - and the state and national parties backing them - are locked in a back-and-forth game of one-upmanship to show their man is the most dedicated to preserving the federal benefit programs vital to seniors.
More than $1 million has been spent already on attack-style TV ads focused almost entirely on the candidates' positions on Medicare and Social Security.
The uncertain future of the programs has long been a hot political topic. But it's been heightened in this Southern Arizona election because both sides see vulnerabilities in their opponent. The older demographic in the district has also pushed it to the forefront.
Barber and Democrats remind voters daily that two years ago Kelly said he wanted to privatize and phase out Social Security and eliminate Medicare. They slam his pledge this go-round to protect the programs as a disingenuous trick.
Kelly and Republicans continue to link Barber to the Democrat-backed Affordable Care Act of 2010, approved with the support of Barber's former boss. It includes more than $500 billion in future spending cuts to Medicare.
Barber, of course, did not vote for or against "Obmacare" and has said he would reform parts of the law. But he was Giffords' longtime district director and is her chosen successor, and the GOP regularly reminds voters of the link.
Both sides know, too, that older voters could decide this election, said Republican pollster Margaret Kenski. In lower-turnout primaries and special elections, often more than half of people who cast ballots are over 65, Kenski said.
"It's not surprising that Social Security and Medicare would take center stage as issues when so many of the voters are eligible for both of those," Kenski said. "It raises fear in people who are getting older."
Forty-one percent of voting-age people in CD8 are at least 55 years old, 2010 U.S. census numbers show. That's a higher percentage than any of the other seven congressional districts in Arizona. Only CD2 has a higher percentage of potential voters who are at least 65 years old.
And the four counties CD8 touches have a higher percentage of people enrolled in Medicare Advantage than the state or the nation - 42 percent of residents in Pima, Cochise, Pinal and Santa Cruz counties are in the program, compared with 38 percent statewide and 27 percent nationwide, government figures for April 2012 show.
That's important because the Affordable Care Act includes an estimated $145 billion in cuts over 10 years to Medicare Advantage plans, which are operated by private insurers and approved by the Centers for Medicare and Medicaid Services. That translates to a disproportionate hit on CD8 pocketbooks.
Legislative fixes are needed
The future looks bleak for Social Security and Medicare, which could both be operating in the red within two decades if Congress doesn't act.
The 2012 annual report from the Trustees of Social Security and Medicare says Social Security will only be fully solvent through 2033. After that, benefits would be ratcheted down. Medicare will only be able to fully pay for Part A, which covers hospital costs, through 2024 before it starts scaling back.
Both programs will cost more in the future because of an aging population and, in the case of Medicare, because of rising medical costs.
The Affordable Care Act includes a $145 billion cut to Medicare Advantage that is part of $575 billion in spending reductions for Medicare over the next 10 years, says an April 2010 memo from the Centers for Medicare and Medicaid Services.
Democrats say some of the reductions will not mean cuts in service. For instance, the cuts to Medicare Advantage are to come by reducing spending per person down to levels that are spent in the traditional Medicare program by paying medical providers less, the memo says. Another estimated $233 billion in spending reductions is to come from scaling back how much hospitals and doctors are paid under traditional Medicare.
Even with those cuts, Medicare spending will increase in response to a rapidly growing older population, from $520 billion in 2010 to $949 billion in 2020, the Congressional Budget Office reports. But spending per capita won't continue at the current pace.
Both candidates acknowledge it's a critical issue.
Barber's first campaign event was at a senior living apartment complex, where he reaffirmed his commitment to protecting Medicare and not privatizing Social Security.
Kelly has spent an increasing amount of time recently talking about the two programs, saying, "These are not welfare programs. These are programs people have paid into all their lives, and we will honor our commitments."
Kelly: no change in views
In response to the buffeting he's taken over comments from his 2010 campaign, Kelly has been doing all he can this time around to reassure voters he will protect those benefits.
He held a press conference with a group of seniors who say they support him. He produced a TV ad with his grandfather in which he promises he'll protect seniors' benefits. He announced an endorsement from the 60 Plus Association.
Earlier this month, yellow stickers were pasted on Kelly's blue campaign signs around the city with the words, "Repeal Obamacare" and "Protect Medicare." He also overhauled his official stance on Social Security and Medicare on his website, adding that he's against privatization of Social Security and for a bipartisan solution for Medicare.
But Democrats have been driving home a message to voters they should not trust a man who two short years ago sang such a different tune. Barber spokesman Rodd McLeod said what's troublesome is Kelly has not admitted he was wrong and explained why he's changed his opinion, but rather tried to act like he never said it.
Kelly says he's always been consistent on the issue.
"The Barber campaign has a great video guy and the ability to attempt to scare seniors into voting a certain way," Kelly said Friday. What is edited out of the TV videos Democrats are pushing, he said, are his comments from those same interviews about "protecting the seniors who are currently on Medicare and Social Security."
His plan to protect the programs is to cultivate more American energy, which will create jobs. With more taxpayers, there will be more revenues for the federal government to pay Social Security and Medicare benefits, he says.
His opinion on privatization - whether to offer younger workers an option of putting a portion of their contribution into personal retirement accounts - remains unclear. A paragraph on his website advocating that option was removed earlier this month.
But he reiterated support for that option at a press conference Friday.
"Maybe you put half of your payroll taxes in a personal account so the government can't touch it," Kelly said.
Americans should be able to decide if they want Social Security and Medicare in the future, he said.
"The American people have always been able to make better decisions for themselves than the government forcing a decision on them," Kelly said.
Asked if that would be a private system, he said it's a system of "American people choosing what they want."
Barber and 'obamacare'
Surrounded by about 150 senior supporters on Monday, Barber celebrated an endorsement of the National Committee to Preserve Social Security and Medicare.
He used the event to drive home his claim that he's the only candidate who can be trusted to protect Social Security and prevent cuts to Medicare benefits.
"My opponent is experiencing an extreme makeover," Barber said. "What I have said from the very beginning is what I'm saying here today. No change. No wavering. No flip-flopping."
Republicans don't see it that way.
Though Barber is making his first run for public office, the GOP is telling voters in TV ads, mailers and emails that he supports cuts to Medicare, linking him to the Affordable Care Act through his association with Giffords.
"The facts are that Ron Barber does support Obamacare. He will not support repeal of Obamacare," Kelly said this week. "I will absolutely vote immediately to repeal Obamacare."
Barber has said the health-care reform law was "far from perfect," and parts of it need to be amended. He's counting on voters to understand he wasn't in office to vote on the law, and that his job as Giffords' district director did not include drafting bills.
"Obviously, I wasn't involved in shaping a major piece of legislation," Barber said. "Neither, quite frankly, was Congresswoman Giffords. A bill like that is shaped in the committees of jurisdiction. She wasn't on any of the committees of jurisdiction."
Barber offers several proposals to help shore up the future of the two benefit programs. On Social Security, he said we must get people back to work so more people are paying into the system, and consider adjustments to the program to extend its solvency. Asked if that means raising the retirement age, he said everything should be considered.
On Medicare, Barber says the federal government should immediately be allowed to negotiate the price of medications just as Veterans Affairs does. It also needs to fix Medicare Part D, prescription drug coverage, which been a factor in reducing the solvency of Medicare. Also, the government needs to be more aggressive to weed out fraud and abuse in Medicare, he said.
He's against any privatization of the programs or making them voluntary.
"If healthy seniors walk away, it will make Medicare much more expensive for those who need it the most," Barber said. On Social Security privatization, he said: "We cannot gamble the hard-earned dollars of Arizona's seniors on the stock market."
On StarNet: Read the Star's local politics blog, Pueblo Politics, at azstarnet.com/pueblopolitics
Contact reporter Brady McCombs at 573-4213 or firstname.lastname@example.com


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This November we are participating in Ricochet and Away's Ring Your Neck Scarf Challenge. The guidelines were pretty straightforward, make a scarf, crocheted or knitting must be kept to 20% or less of the final product, get creative and try something new! We created a hooded scarf for Miss M, here is how.
My little model was so not in the mood for her photo shoot. Something about these pictures seemed old time-y to me. So I helped them along a little.
The scarf/hood combo we made is super easy! You'll need a chunk of fleece, accent yarn, and 30 minutes.
You're going to cut 2 rectangles, these will be your scarf. Our rectangles measure 3″x24″. Make sure your rectangles stretch runs width wise. If you want to be able to wrap your scarf around more make your scarf longer.
Now you need your hood. You'll again be cutting 2 pieces, with the stretch running front to back NOT top to bottom.
You can trace from an existing hood, or use a pattern piece you have on hand. Add a couple inches straight down from where there chin will be, this will bunch around their neck and keep them cozy!
Sew with right sides together. Simply stitch your scarf ends into the seam in that portion under the chin. Then sew your hood right sides together from the back of the neck to the forehead. Flip it right side out!
Fleece won't fray or unravel so there is no hemming or extra finishing needed.
Donna went in and added the crocheted edge to our hooded scarf. It was our new skill for this project. We like how it turned out, adds a little something sweet.
I like this tied in a bow, but the scarf can be simply wrapped, tied in a knot or styled however you would like.
I tried to bribe with a cookie for a smiling picture. I got a picture with a cookie…
Any interest in a tutorial breaking down adding a crocheted edge to your fleece hooded scarf?
Happy Sewing,
Rachel and Donna
We link to these Parties
It's voting time! We would love your support.
Join the sewing circle. Get the Newsletter.
Want to be part of the sewing, tutorials, and never miss the freebies and sales?


text:
"For the smartphone market, we have made some truly exciting progress in the past eight months since the launch of our smartphone product platform. During this time, we have accumulated over 10 million smartphone users who are utilizing our smartphone application store, browser, games, game center and PC assistant on a regular basis. Over the coming quarters we anticipate this strong growth to continue as we see greater adoption of low-cost smartphones begin to take hold. Moreover, we have cemented strategic partnerships with over 160 smartphone handset partners. These partners are preinstalling our products, which we expect will further expand our user base and content offerings. We also anticipate additional growth through the offline store front from strategic partnership wins with Suning as well as forming other similar strategic partnerships covering important distribution points for low cost smartphones. Given our recent success, we are increasingly confident that we are implementing the correct strategy for successfully targeting the Chinese smartphone market."Carl Yeung, Chief Financial Officer of Sky-mobi, commented, "We were encouraged by exceeding our revenue guidance, along with our operating profit, net income and cash flow all being positive. Despite the year over year decline in revenues, we believe that the 5.1% sequential revenue growth, the improvement in non-IRFS gross margin and a turnaround in non-IFRS profitability from a net loss last quarter are trending in the right direction. These sequential improvements are clearly a testament to our ability to adapt quickly to the changing mobile Internet market with effective operating strategies. Moreover, we are very excited that our revenue composition continues to improve with a new high of 30% of revenues coming from higher ARPU associated with our Maopao community, giving us a strong foundation for future expansion in revenue and margin over the long run. Overall, this quarter's results demonstrate management's commitment to maintaining a healthy financial profile while evolving with new initiatives to stay in front of China's dynamic mobile marketplace."
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text:
Forget the tuxedo. Jerry Seinfeld made his big appearance at the Cannes Film Festival wearing a fuzzy bumblebee suit and black tights.
"You know, one thing I hate is any kind of movie promotion that smacks of desperation in any way," the 53-year-old comedian said, before jumping from the roof of an eight-story luxury hotel, arms and legs flailing, and heading down to the beach on a cord.
Seinfeld's "Bee Movie" is the latest DreamWorks Animation film to dramatize the secret life of a pesky insect (following "Antz"). It doesn't open until November, but Seinfeld was in Cannes on Thursday showing 30 minutes of highlights. He has spent the past four years developing the film, writing the script and giving voice to its leading role.
His character, Barry B. Benson, is an ambitious young bee who dreams of life beyond the hive. After discovering that humans have stolen honey from bees through the ages, he takes the human race to court to try to right the injustice.
Other voices include Chris Rock as a mosquito trying to avoid being squished on a truck window; Renee Zellweger as a human florist who inspires a cross-species crush in Benson; and Matthew Broderick as Benson's best friend.
Before the stunt, Seinfeld worked the microphone at a Cannes theater where he screened the rough footage. The press corps tried to engage him in a little standup comedy.
"I would like to know if `to bee or not to bee' is the theme of the movie," one reporter asked.
"That's a joke we also tried," Seinfeld quipped.
Another journalist ventured: "Will be there be a `Cee' and a `Dee' movie?"
Seinfeld gestured to Rock and suggested: "Why don't we handle the humor aspect?"
Rock, who voiced Marty the zebra in "Madagascar," said "Bee Movie" was different from most other DreamWorks creations because the humor is all Seinfeld's.
"This one has a singular vision, that's what I really like about it," Rock, 42, said. "Most animated movies are made by committee, and the comedy is scattered. They're great, but this one feels like a handmade suit."
Jeffrey Katzenberg, chief executive of DreamWorks Animation SKG Inc., said that watching Seinfeld's "creative process is amazing, something akin to seeing a world- class athlete up close and personal."
"My belief in the film and confidence is that Jerry is actually going to bring animation to a whole new audience of people who may have not thought of these as for them, and at the same time it will continue to work as a family film," he said.
In one hilarious courtroom scene, Benson berates Sting (voiced by the singer) for stealing his moniker from the bee community. He narrowly escapes death at the hands of humans who swat at him with magazines — and he proclaims hefty Italian Vogue to be especially perilous.
Seinfeld said the idea for "Bee Movie" popped randomly into his head one day as he was eating candy. The next day, he was invited to eat dinner with Steven Spielberg.
"For a Jewish boy growing up on Long Island, to have dinner with Steven Spielberg is like being bar mitzvahed twice," Seinfeld said. The comedian claims he pitched the "Bee Movie" idea during an awkward lull in the conversation.
"I just wanted to get through the dinner and say I had dinner with Steven Spielberg, and he gets excited," Seinfeld said. "And that's how this happened."


text:
Attend a PMI-ACP Exam Prep course in the DENVER area:
Our course contains the following program:
History and Origins of Agile Development
Software development is sometimes called a
wicked problem. Like predicting weather,
or the stock market, accurate project estimates and acceptable project outputs continue
to be a challenge for the average software project. In 2001 the Agile Manifesto
was signed, and so began the Agile Development movement. Various flavors of Agile
exist today, with Scrum being the most widely-adopted practice.
How Agile Maps to the PMBOK
Agile Tools & Techniques
Domain I - Value Driven Delivery
Instead of process-driven
delivery, Agile Development is based on a value-driven approach. Teams are
encouraged to work with project stakeholders to prioritize the most valuable
features that can be packaged and delivered to paying customers in successive
increments. An emphasis is placed on targeting specific user-types, or value
thresholds so that the products can be placed in front of real customers
who can then in-turn provide quicker product feedback.
Domain II - Stakeholder Engagement
Involving stakeholders throughout the project development process is essential in
succeeding with value-driven delivery. Communicating about stakeholder objectives,
customer value, project progress, and changes in the environment are an ongoing
necessity. We'll explore brainstorming techniques, feedback channels, prototyping,
simulation, product-demos, facilitation, participatory decision models, globalization,
and cultural awareness practices that are helpful with engaging stakeholders effectively.
Domain III - Boosting Team Performance Practices
The team is the engine in an agile project. Value is delivered as fast as the team
can perform. The team is only as fast as the slowest member, and gains velocity as each
member focuses on the same target. We'll explore ways to create and support self-governing
teams through empowerment, knowledge sharing, motivation, rewards & recognition,
and innovation games. We'll discuss ways to measure the teams progress and continuously
improve performance. Finally, we'll examine the team as a corporate asset and discuss
ways to maximize the business value of a high-performing team.
Domain IV - Adaptive Planning
In an Agile project, planning happens at multiple levels. We'll explore strategic,
release, iteration, and daily planning. Agile is commitment-based. Commitments are
made during these planning junctures based on a balance of priorities vs. team capabilities.
The team quickly learns to adapt to whatever mechanisms work best in their unique environment. Project progress is tracked, as well as velocity, throughput, and cycle-time.
A closed-loop feedback process is used to continuously improve team and individual
Domain V - Problem Detection and Resolution
Risk are identified and explored early in what agile practitioners call 'spikes.'
An open and safe environment is encouraged to surface team and workplace issues
early, before they become showstoppers. Team members are encouraged to publicly
display progress impediments so that management can escalate accordingly. Risk status
is communicated regularly to stakeholders so that their expectations are managed
Domain VI - Continuous Improvement
Agile philosophies transcend individual projects. A fully functional agile team
is considered an asset to the corporation. Teams perform retrospectives after each
sprint to brainstorm how they could have performed more effectively. They use this
insight to improve future performance. Similarly, individual retrospectives and
product retrospectives are tools which improve individual progress and product value,
Additional Agile Knowledge and Skills, separated into three levels of importance:
Level 1
Level 2
Level 3
Agile Adoption Within Your Organization
Finally, we'll discuss successful approaches for adopting Agile practices within
your organization.


text:
APC Network Management Card 2 with Environmental Monitoring - Remote management adapter - 10/100 Ethernet - for Smart-UPS 1000, 1500, 2200, 3000, 750; Smart-UPS RM 3000VA; Smart-UPS (AP9631)Item#: 7785843 | Model#: AP9631
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APC UPS Network Management Card 2 with Environment Product Details
APC AP9631 UPS Network Management Card 2 with Environmental Monitoring
The APC AP9631 UPS Network Management Card 2 with Environmental Monitoring. This APC AP9631 UPS Network Management Card 2 delivers secure monitoring and control of an individual APC UPS via web browser, command line interface, or SNMP. Embedded technology provides reliability with notification features that inform you of problems as they occur. For protected servers, the included PowerChute Network Shutdown software provides graceful, unattended shutdown in the event of an extended power outage, always keeping business information safe. The APC AP9631 UPS Network Management Card 2 with Environmental Monitoring support allows you to connect temperature sensors, or relay input/output connectors that support two input contacts and one output relay.
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text: This'll 'do for now By The Associated Press December 24, 2012 Story Share The Associated Press Michael Paris, of Chester, portrays TNA pro wrestler Zema Ion. CHARLESTON, W.Va. -- More than six years after entering West Virginia University, Michael Paris got his advertising degree this month. And for as long as he can, he doesn't plan to use it.Not while he's traveling the globe for TNA wrestling, which signed him in June 2011 as alter ego Zema Ion, a hair-obsessed Filipino supermodel."Right now I'm having the time of my life living my dream as a professional wrestler," said Paris, 26. "Anything I can do to avoid using my advertising degree, I'm going to make the most of those opportunities."While he spent much of his college career traveling to small-scale wrestling gigs, Paris now flies every week to a soundstage at Universal Studios in Orlando, Fla., to tape segments that are televised on Spike TV.Zema Ion's storyline is simple."Every two seconds he's spraying his hair, making sure it's still in place," Paris explains. "And, of course, this leads to my opponent constantly trying to messing it up, and Zema Ion then just going crazy and becoming aggressive because his opponent is messing up his hair."It's a passion that bit Paris at an early age while growing up in the northern West Virginia community of Chester.His father, a horse trainer, would spend months at a time on the road and return with wrestling figurines as presents for his children. Paris and his father often spent Saturday mornings watching wrestling on television. His father died when Paris was 5."It's one of my only memories of him," Paris said. "As my mom told it, I just wanted to be like my dad."As a ninth-grader, Paris received a wrestling videotape in the mail the day he was supposed to go after a spot on the Oak Glen High School basketball team. He never made it to the tryouts. His father's best friend, Richard Lavell, became the son's mentor, paying for Paris to attend the Elizabeth, Pa.-based International Wrestling Cartel academy when he was 16, driving him an hour-and-a-half every week, then traveling to pro matches across Pennsylvania and Ohio."Without Richard, none of this would be possible," Paris said. "He was the one responsible for my whole career."Lavell downplayed his own role."I'm sure he'd have figured out a way," Lavell said. "He was always crazy about it."IWC trainer Joe McMunn said Paris was one of the youngest students the academy ever had. Yet something made Paris stand out. "He was more mature than some of the guys who were two, three, four years older than him," McMunn said. "He had good discipline to begin with. We were able to really build on that with him."While attending college, Paris struggled to make ends meet as he traveled to wrestling performances. His brother, Steve, who had already graduated from WVU, paid for Michael Paris' rent for a year to enable him to continue wrestling."My brother is definitely another unsung hero in the story of Michael Paris," he said.In 2010, Paris was invited to an open casting call for industry giant World Wrestling Entertainment. He was among 60 wrestlers selected to try out from among thousands of applicants. He didn't make WWE's final cut and was told he wasn't quite ready.Paris started to second-guess himself. At 5-foot-9 and 170 pounds, he thought, perhaps he was too small for the big time. Meanwhile, the friends who attended advertising school with him graduated in May 2011, while he was still a few credits short."That's when I was like, man, there ain't nothing going right," Paris said. "I failed at wrestling. I still haven't graduated college. Is there ever going to be a light at the end of the tunnel?" Less than a month later, there was.He got a phone call from a TNA representative asking him to come to a tryout. Nashville, Tenn.-based TNA's top wrestling talent includes veteran wrestler and actor Hulk Hogan.Paris still doesn't know how the organization got his phone number. He was told a TNA talent representative saw a video of him on YouTube.He survived his tryout, which was broadcast live on Spike TV, and hasn't slowed down since.In addition to his weekly trips to Orlando, this year Paris has wrestled in India and Mexico City, along with trips to Canada and places like Chicago and Phoenix.But there was still that issue of college. When TNA signed him, Paris had been at WVU five years. Despite the travel challenges, he got it done, taking one class each semester over his final two years in order to graduate.When his body won't let him wrestle anymore, Paris not only can turn to his advertising degree, he can try spinning records. He's been training since June to become a disc jockey, a dream that morphed from an interest in music before he realized he had no talent singing or playing guitar."I'm not unrealistic about it," he said. "I could break my leg tomorrow wrestling. That would be the end of my career. Without a college career to fall back on, I don't know what I'd be doing with my life."When it comes to importance, mentor and family friend Lavell said there's no comparing the pecking order of a diploma to a wrestling career."Graduation. Most definitely," he said. Story Share Story Share Trending Now 1 Deer in 8 WV counties found dead from EHD 2 New company planning $73M synthetic fuel plant in Greenbrier County 3 WVU law professor announces run for Congress 4 Morgantown coal operator Laurita indicted in alleged campaign finance scheme 5 Richwood mayor on leave amid investigation of purchases An inflated sense of elf Previous Story W.Va. native reflects on year as National Cathedral dean Next Story


text: Canon's compact camcorder features full 1080p recording at up to 60 frames per second! It has a 3.5" OLED touch panel display to allow you to easily change camera functions. This camera also features dual SD card slots, 2 XLR audio inputs, and a 20x optical zoom lens with Canon's Optical Image Stabilization built right in. One of my personal favorite features is the built-in WiFi which makes the camera controllable through Canon's app. We include one Canon BP-820 Battery, one Canon CG-800 Battery Charger, and an AC Adapter (which can also charge the battery in the camera.)


text:
First up, Holydragoon21 has a review of Grandia II for the PS2. What makes this review interesting is that Holydragoon never played the DC version--so you're getting a review that judges the game entirely on its own merits.
And if that wasn't enough, we've got two new reviews from Dragoonman (what's with all the Dragoons today?) For starters, take a stroll down memory lane with a Final Fantasy Mystic Quest critique.
And when you're done there, be sure to catch Dragoonman's review of the new GBA action RPG, Dragonball Z: The Legacy of Goku. DBZ fans may want to read this one before running out and spendind their hard-earned cash.
Sunday, September 24 • 10am PDT/1pm EDT
Final Fantasy XII: The Zodiac Age
Mondays • 6pm PDT/9pm EDT
Vandal Hearts
Tuesdays • 12pm PDT/3pm EDT
Danganronpa 2
Tuesday-Thursdays • 5pm PDT/8pm EDT