text:
Staccato Loxapine Multidose PK
This study has been completed.
Alexza Pharmaceuticals, Inc.
Atlanta Center for Medical Research
Information provided by (Responsible Party):
Alexza Pharmaceuticals, Inc.
ClinicalTrials.gov Identifier:
First received: November 6, 2007
Last updated: March 13, 2017
Last verified: June 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been completed.
|Study Completion Date:
|December 2007
|Primary Completion Date:
|December 2007 (Final data collection date for primary outcome measure)


text:
South Jordan's mayor desires to destroy the beautiful green space of the popular landmark, Mulligan's Golf and Games. Located along the Jordan River, Mulligan's has the best of both worlds — the entertainment of a nine-hole golf course, batting cages and heated driving range that attract over 250,000 patrons a year, as well as the scarcity of open space along a protected river that brings migratory birds and other rare wildlife seldom seen in a city.
It seems our city leaders would choose to add more housing, commercial development and in particular, Hale Center Theatre over saving an activity and family-oriented outdoor facility in what looks like the Garden of Eden.
Isn't it time for the City Council to hear the citizens and see more than dollar signs? Don't we want future generations to be physically active and utilizing the healing powers of nature right here in our own city rather than sitting down and being entertained? If Hale Center is wanted in South Jordan, locate it on a different plot of land. Some things are more important than money.
Kerry Dalling
South Jordan

subset: commoncrawl


text:
Cornejo-Olivas MR, Yu CE, Mazzetti P, Mata IF, Meza M, Lindo-Samanamud S, Leverenz JB, Bird TD. Clinical and molecular studies reveal a PSEN1 mutation (L153V) in a Peruvian family with early-onset Alzheimer's disease. Neurosci Lett. 2014 Mar 20;563:140-3. Epub 2014 Feb 2 PubMed.
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Tucson firefighters rescued 15 dogs and several other animals from a burning midtown home.
According to the Fire Department, two young children are among three people who went to a hospital for precautionary reasons.
Firefighters arriving at the burning home late Tuesday found flames and heavy smoke inside due a fire that was accidentally started in the kitchen area.
No humans were inside when firefighters arrived but they found numerous animals that they rescued. Along with the 15 dogs, the animals included small animals such as mice.
The Fire Department says the Pima County Animal Care Center is caring for the animals until the owners are able to make proper arrangements.
Copyright 2013 Associated Press. All rights reserved.


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Jarrow ( or ) is a town in north-east England, located on the River Tyne, with a population of 27,526. Historically part of County Durham, in 1974 it became part of the metropolitan county of Tyne and Wear.
In the 8th century, the monastery of Saint Paul in Jarrow was the home of Bede, who is regarded as the greatest Anglo-Saxon scholar and the father of English history. From the middle of the 19th century until 1935, Jarrow was a centre for shipbuilding, and was the starting point of the Jarrow March against unemployment in 1936.
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text:
HGTV's Hidden Potential
Anyone else impressed by this show and the rendering software they use in particular?
It looks as if I'm not the only one who has shown interest in just how they do that.
How long do you think it takes for them to put something like that together?
HGTV's Hidden Potential
How can cultural elitists like ourselves put TV in the Culture category? Well, where the hell else is it going to fit?
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LargeMarge wrote:I think the software is neat. However, the show annoys me because they don't show what the people ultimately did with the space.
Also, there are times where they are clearly cheating. I recently saw an episode where they claimed they were leaving the appliances because of cost, but in the rendering, they were replaced with stainless appliances. I suspect that what they show is not meant to be accurate beyond the architectural details.
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Convert the text and images from PDF documents into editable MS Word (.doc, .docx) for easy editing.
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text:
NewswireToday - /newswire/ -
Taipei, Taiwan, 2006/08/23 - Streaming21, today announced that it has successfully rolled-out Japans most popular residential Video-On-Demand (VOD) & IP Broadcasting services for GEO@Channel, operated by Enterwave.
GEO@Channel will be the first IP broadcasting service in Japan that offers full-screen TV playback with delivery through open networks. In contrast to traditional live video channels over the Internet that users often see on the PC, the GEO@Channel uses Set-top Box (STB) with high-quality, full-motion video playback on TV. Also, unlike traditional IPTV services, which rely on expensive managed network, GEO@Channel service works over the Internet and is available to any broadband users in Japan, regardless of domestic ISP to which users subscribe. This unique home entertainment service targets to capture millions of new users by the end of this year on a national scale.
Shinichi Asano, President of Enterwave said, Thanks to Streaming21s groundbreaking technology, GEO@channel can now offer appealing VOD and live broadcast services to subscribers from any ISP. Streaming21s innovative IPTV technologies break the boundaries and limitations that telcos and broadband service operators have been suffering from closed IP environment. By adapting Streaming21s solutions, we will continue to enjoy tremendous increases in subscribers and ARPU.
GEO[.]Channel offers more than 5 channels with expansion capability to 40 channels, including Americas hottest Nickelodeon channels for Children (Japanese and English), e-weather.net, Bloomberg Television, Paradise TV and Reality TV, etc. It also allows members to rent Hollywood movies, Japanese movies, animations, and TV drama titles without having to visit a video shop (through NEO Index's Nextensive VOD service) and access various other broadband-based services in the comfort of their home by simply hooking up a special tuner (Set-Top Box or STB) to the TV set.
Dr. Joe Lin, President and CEO of Streaming21 said, "Enterwaves GEO@Channel represents one of the most exciting successful stories in Japans IPTV history. This milestone project further strengthens Streaming21's unwavering commitment to working with Enterwave, Japan's leading VOD service provider, to create compelling new TV experiences that will attract customers and add tremendous values to service providers." He added, Streaming21 is the worlds only interactive IPTV solutions provider over fixed, mobile and open networks. The companys innovative adaptive jitter management technology enables jitter-free stream delivery over open network compared to a managed network to operate IPTV services. Not only Tier 1 Telco could offer IPTV service, but also any xSP could easily provide IPTV without dedicated networks. This breakthrough technology is running successfully in Japan. We expect to replicate our successes to our customers in Asia Pacific, Europe and then to the US soon.
Streaming21 has won many Tier 1 Telcos and IPTV service providers, including NTT Communications, Index Group, VIC TOKAI and TEPCO in Japan, as well as Korea Telecom (KT), and Taiwans Chunghwa Telecom (CHT). Streaming21 team helps customers rollout IPTV services with world-class efficiency and professionalism.
Written by / Agency / Source: Streaming21, Inc.
Availability: All Regions (Including Int'l)
Traffic Booster: [/] Quick Newswire Today Visibility Checker
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2007 LinuxQuestions.org Members Choice Awards
04 January, 2008Drew Bentley, a long time user of psad, emailed me to mention that he had voted for psad to be included within the 2007 LinuxQuestions.org Members Choice Awards in the category of Network Security Application of the Year. Although there are many security projects out there that outstrip the Cipherdyne projects, my personal hope would be that eventually fwknop might be included in the Members Choice Awards someday. The rise of service authorization via passive means embodied by Single Packet Authorization allows the security model employed by VPN services and software such as SSH to be strengthened with a default-drop packet filter. This reduces the number of functions - any one of which has a non-zero probability of containing a security vulnerability - that an attacker can tweak from arbitrary source IP addresses.
I personally sleep better at night knowing that my SSH daemon can only be reached after a would-be client is passively authenticated and authorized to communicate through the iptables policy by sending a properly encrypted and non-replayed SPA packet. Anyone scanning for my SSH daemon with nmap cannot even see that it is listening.


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LA PUENTE >> More than three-dozen family members and friends gathered with candles last weekend to mark the first anniversary of the fatal shooting of a La Puente man who officials said fled from a traffic stop while armed with a handgun.
Ceaser Joe Mendoza, 24, died at a hospital soon after he was shot and wounded by a sheriff's deputy about 9:50 p.m. June 22, 2013 along Loukelton Street just west of Ballista Avenue, according to Los Angeles County sheriff's and coroner's officials.
"Even several weeks after he was gone, I kept walking around thinking I'd seen him," sister-in-law Joeie Martinez said.
"He was the happiest person ever. He would always make the best of any situation," she said. "He was so giving. If you needed something, he'd find a way to give it to you."
Mendoza was a passenger in a car with two other men when it was pulled over by a sheriff's patrol car for running a stop sign, according to Los Angeles County sheriff's and district attorney's officials. One deputy remained with the two men in the stopped car, while Deputy Chad Sessman chased after Mendoza.
Authorities allege he reached for a 9mm handgun that was tucked into his waistband while fleeing, prompting Sessman to open fire.
Shortly after the shooting, sheriff's officials said in a written statement that Mendoza twice faced Sessman and reached for the handgun while running, though detectives said he never fully removed it from his pants.
Family members conceded that Mendoza was armed and that he ran from deputies, but have said they don't believe he assaulted a deputy, or intended to. And the autopsy report confirmed the family's assertion that Mendoza had been shot in the back.
Officials at the Los Angeles County District Attorney's Office ultimately determined the deputy-involved shooting was lawful self-defense.
Another passenger of the Nissan Altima told investigators that Mendoza became "extremely nervous" when the car was pulled over by deputies, and said that he had a gun on him and needed to run, according to the district attorney's office report on the shooting.
"As Mendoza ran from Sessman, he tripped and fell onto the ground landing on his buttocks facing Sessman," according to the report. "Sessman saw that Mendoza had a chrome handgun in his waistband. Mendoza looked directly at Sessman, reached for his waistband and grabbed the handgun with both hands. Believing Mendoza was preparing to draw the firearm and shoot him, Sessman drew his service weapon and fired at Mendoza."
Mendoza returned to his feet and continued running west on Loukelton Street, officials said.
"As Mendoza ran, he kept his arms in front of him near his waist. Mendoza was moving his hands near his waist and periodically looking over his left shoulder toward Sessman," the district attorney's report said. "Sessman moved into position behind a concrete fence post and fired a second salvo at Mendoza."
"Sessman believed Mendoza was attempting to draw his firearm from its holster and scanning over his left shoulder for Sessman. Believing that Mendoza was preparing to shoot him, Sessman fired his weapon again to end what he perceived to be a deadly threat," according to the district attorney's report.
The district attorney's report differed from the initial statement released by the sheriff's department, which stated that Mendoza, "turned around a second time reaching for his waistband."
Mendoza fell wounded and was taken to a hospital, where he died from his injuries less than an hour later, Los Angeles County Department of Coroner Assistant Chief of Operations Ed Winter said.
Sessman fired five shots, according to the district attorney's office.
Mendoza was struck by three .45-caliber bullets, according to the coroner's autopsy report. The fatal wound was to the center of his back. Another bullet struck him struck him on the left, rear side of his hip, and the third penetrated the back of his right arm.
The district attorney's investigation into the shooting was completed on April, concluding that, "LASD Deputy Chad Sessman acted lawfully in self-defense. We are closing out file and will take no further action in this matter."


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The Mpumalanga transport department has blamed the deterioration of the R36 between Machadodorp and Mashishing (formerly Lydenburg) in Mpumalanga on heavy trucks and rain.
Social media was abuzz following the story about a woman who decided to prove a point by taking a bath in one of the potholes last week - which made front-page headlines over the weekend.
Department spokesman Dumisani Malamule said this week: "Much maintenance has been done on the road, but the large number of heavy trucks from various mines that use the road have contributed to the deterioration of the surface.
"The road has now deteriorated to the point where patching is not a feasible option anymore."
"Rehabilitation is required."
Malamule said the rehabilitation would be done in the 2014/15 financial year.
Lydenburg Guest Farm owner Alison Botha and volunteer teacher Rosie Morrison recently published photos of Morrison - complete with shower cap, book, glass of wine and shampoo - taking a bath in one of the potholes on the R36.
They posted the photos on Facebook and encouraged people to spread the message that government had to fix potholes that threatened the lives of tourists and locals.
"It is the responsibility of government to fix this road."
Botha said: "This specific road, the R36 between Machadodorp and Mashishing, has been unusable for years now and it's mainly because there are 40-ton trucks that make use of the road every day due to a lack of railway structure."
Botha said she used to take guests out on horse trails, but the road had become so damaged that neither her horses nor vehicles could use it.
"It's simply too dangerous," she said.
Malamule said government would make every effort to ensure the road was rehabilitated.
"As we are approaching the end of the current financial year, all efforts are being made to ensure that rehabilitation of the road is done in the 2014/15 financial year. The MEC will pronounce the plans for the provincial road network during the 2014/15 policy and budget speech." - Sapa


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Canadian name
|This article needs attention from an expert in Canada, Indigenous peoples of North America or Ethnic groups. The specific problem is: § Aboriginal Canadian names is blank, even though it's mentioned first in the lede and should be the longest, there being 634(!) recognized First Nations. (June 2011)
Canadian naming conventions vary based on whether one is Aboriginal Canadian, English Canadian or French Canadian.
English Canadian names[edit]
|This section needs expansion. You can help by adding to it. (January 2011)
In English Canada, names follow much the same convention as they do in the United States and United Kingdom. The first name on the birth certificate is the name the child is expected to go by, although use of a middle name in everyday life is not uncommon. The last name is usually the same as the father's last name though it is not unheard of for children to take their mother's last name, or for both names to be hyphenated. Middle names are optional and are generally only used on official documentation. Multiple middle names are rare but are officially recognized.[1]
With the exception of Quebec, either spouse, though usually the wife, has the right to assume the last name of their spouse after marriage, as long as it is not intended for the purposes of fraud. Getting married does not result in a legal change of name or automatic change to your identification or records. Their marriage certificate is considered proof of their new name.[2][3]
One of Canada's chief values is multiculturalism. As such, it is not uncommon to see names that follow patterns differing from the English and French naming conventions.
French Canadian names[edit]
- Given names in Quebec
In French Canada, up until the late 1960s, children of Roman Catholic origin were given three names at birth (usually not hyphenated): the first, Marie or Joseph, usually indicated the gender of the child. The second was usually the name of the godfather or godmother, while the third and last given name was the name used in everyday situations.[citation needed] Thus, a child prenamed Joseph Bruno Jean on his birth or baptismal certificate would indicate the baby was a boy, the godfather's first name was Bruno and that the child would be called Jean (and not Joseph) for all intents and purposes of everyday life. A real-life example of this naming convention was that of Canadian prime minister Jean Chrétien, who was born Joseph Jacques Jean Chrétien.
Although it is still permitted to list multiple names on a birth, it is uncommon for people to even be aware of their other given names, and the practice of using religious names became increasingly rarer after the Quiet Revolution as baptism ceremonies gradually became less common. The Quebec government officially recommends not using more than four given names.[4]
- Surnames in Quebec
Currently, most couples give the child the surname of the father, though the Quebec civil code allows a couple to combine at most two of their surnames, with or without hyphens.[5] Thus a couple named Joseph Bouchard-Tremblay and Marie Dion-Roy could give to their children the surnames Bouchard, Tremblay, Dion, Roy, Bouchard-Tremblay, Dion-Roy, Bouchard-Dion, Bouchard-Roy, etc. In Quebec, name change upon marriage is no longer automatic, and is difficult or impossible to do if desired. Requests for a name change in Quebec require a reason, and requests to adopt a husband's name after marriage have been denied in the past.[6][7][8]
- The "nom-dit" tradition
Until the late 19th century, several families also had a nom-dit tradition. This was a family nickname (literally a "said name").[9] The origins of the noms-dits were various. Some noms-dits were the war-name of the first settler, while he was a soldier: Hébert dit Jolicœur (Pretty Heart, cf. Braveheart), Thomas dit Tranchemontagne (mountain chopper). Some denoted the place of origin of the first settler: Langevin (Anjou), Barbeau dit Poitevin (Poitou). Others probably denoted a characteristic of the person or of his dwelling: Lacourse, Lépine, Larivière.
Aboriginal Canadian names[edit]
|This section is empty. You can help by adding to it. (June 2015)
Use of titles in Canadian English[edit]
Courtesy titles may be used on official documents in Canada, and are frequently used in formal situations such as business correspondence or meetings.
As in other English-speaking countries, the following courtesy titles are used by default or can be chosen by the bearer when completing a form or application:
- Mr. (Mister) (referencing any male)
- Mrs. (Missus) (referencing a married, widowed, or divorced female)
- Miss (Miss) (referencing a single young female)
- Ms. (Miz) (referencing a female of any age without specifying her marital status).
When referring to a woman whose marital status that one does not know, it is common to write Ms., but no specific rules apply. Using a courtesy title in a non-formal situation may be construed as wrong and awkward.
Although each person has one of the above titles in their name, other titles may be acquired through various ways. The titles of Dr. (doctor) and Prof. (Professor) are acquired through schooling. Often the titles for professors and medical doctors are used instead of the Given name of the individual when being said by one of the individuals students or patients. This does not apply, however, for friends and family and is strictly prohibited to those using the service of the individual and does not know the individual well enough. An example would be for a medical doctor named Mark. His friends would say, "Hello, Mark," but his patients would say, "Hello, doctor."
The parliamentary titles Hon. (honourable) or Rt. Hon. (right honourable) are given to serving cabinet ministers, either federal or provincial/territorial and in some cases are retained for life; for example in the case of retired prime ministers. Senators are designated with the prenominal title Sen. (Senator) while in office.
Foreign titles, such as Sir and Count, are not used; the acceptance of foreign honours by Canadian citizens is not permitted under the Nickle resolution and subsequent Acts of Parliament.
Suffixes always come after the family name, and are also acquired for various reasons. Suffixes are only used in oral communication when necessary, and are also rarely written on the wish of the individual bearing the suffix.
The most common suffixes are Sr. (Senior) and Jr. (Junior). When an individual names their child after themselves or another family member (not necessarily immediate), that individual then bears the suffix Sr. and the offspring bears the suffix Jr., which may also be replaced with II (the second). The suffix "III" is used after either Jr or II and like subsequent numeric suffixes, does not need to happen in one family line. For example, if John and Bob Gruber are brothers and if Bob has a son before John, he will call his son John, II. If John now has a son, his son is John, Jr. As time passes, the III suffix goes to the first born of either John Jr or John II. This is how it is possible and correct for a Jr. to father a IV. Such suffixes are rare amongst French-Canadians due the strongly generational nature of most French given names.
Other completely accepted suffixes include:
- M.D. (Medical Doctor)
- Ph.D. (Doctor of Philosophy)
- MP (Member of Parliament), for federal elected politicians
- Abbreviations for provincially elected politicians:
- MLA (Member of the Legislative Assembly)
- MPP (Member of Provincial Parliament, Ontario only)
- MNA (Member of the National Assembly, Quebec only)
- MHA (Member of the House of Assembly, Newfoundland and Labrador only)
MP and its provincial or territorial equivalents may be followed by the name of the constituency in which that member was elected. For example: Buddy Johnson, M.P. London North-Centre. However, the constituency name or similar designations are not shown of official documents outside of parliament and is never used in casual communication.
Postnominals granted under the Canadian honour system include PC (Privy Councillor, granted to federal cabinet ministers and some other senior politicians including leaders of opposition parties); CM (Member of the Order of Canada); OC (Officer of the Order of Canada); and CC (Companion of the Order of Canada, the highest rank of that order). For a list of other postnominals, including professional titles and orders, provincial honours, and honours in gift of the Crown, see List of post-nominal letters in Canada.
See also[edit]
- ^ Statement of Live Birth Form ServiceOntario.ca
- ^ Assuming/Unassuming a Spouse's or Partner's Name ServiceOntario.ca
- ^ Criteria to apply for Social Insurance Number ServiceCanada.ca - See section 'Supporting Documents'
- ^ Child's given name(s) Directeur de l'état civil, Quebec
- ^ Child's surname Directeur de l'état civil, Quebec
- ^ Marriage - Spouses' names Justice Quebec
- ^ Change of Name Directeur de l'état civil, Quebec
- ^ "Quebec newlywed furious she can't take her husband's name". Canada.com News. August 8, 2007. Archived from the original on 2016-01-02.
- ^ Canadian Genealogy Centre


text:
TiVo Premium Glo Remote
by TiVo | Item #: 81636 | Model #: TIVC00212 |
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About this item
The TiVo Premium Glo Remote is a great replacement for your customers' original TiVo remote. Teach the remote commands from their other the remotes—this unit is learning capable! The keys are backlit for easy readability in a darkened room. This remote works with TiVo Series2, TiVo Series3, TiVo HD & TiVo HD XL, TiVo Premiere & TiVo Premiere XL, Humax Series2, Philips Series1 & Philips, Hughes, Samsung® & RCA DIRECTV DVR boxes with TiVo service. The remote requires 2 AA batteries.
- Controls up to 2 devices including most TiVo® boxes & TVs
- Learning function
- Backlit keys for readability in a darkened room
- Comes standard with TiVo® Premiere XL
Assembled Country
Republic of Korea
Assembled Size
10.4"L x 3.7"W x 2.05"H
Component Country


text:
Meet Dani Bahnsen
My vision is to make a difference in your life by providing motivation, support, and results oriented training on your path to good health and fitness.
Being physically fit and emotionally strong not only increases your energy level and brain function, it also gives you a sense of peace and confidence that will help carry you though your entire life, making you a better parent, spouse, colleague and friend.
Taking care of YOU is one of the greatest gifts you can give yourself and your family.


text:
Celeste Copper Changes Name, Plans to Focus on Cornwall-based Tin Project
Celeste Copper Corp. (TSXV:C) announced that effective immediately it has changed its name to Celeste Mining Corp., but will continue to trade on the TSX Venture Exchange under the symbol "C." The name change is intended to reflect the company's focus on its South Crofty tin project, located in Cornwall, England.
Alan Shoesmith, CEO of Celeste, commented:
Celeste is focused on developing the South Crofty Tin Project in Cornwall, England and we believe that changing our name to Celeste Mining Corp. better reflects the direction the company is heading in to become an important player in the global tin market.
Click here to read the full Celeste Mining Corp. (TSXV:C) press release.


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Departing Bank of Japan Gov. Masaaki Shirakawa expressed regret Tuesday for not being able to end a decades-long struggle with deflation during his "turbulent" five years in office, but added that he believes a recovery is possible.
Speaking on his last day as the central bank chief, Shirakawa appeared at the Diet to speak at a Lower House committee meeting.
"With the easing of the yen and the rising of stock prices, I believe a chance is here," he said.
Shirakawa is set to be replaced by former Asian Development Bank head Haruhiko Kuroda, whose nomination as BOJ chief was approved by both chambers of the Diet last week.
Kuroda, a former Finance Ministry official whose position on monetary policy is close to that of Prime Minister Shinzo Abe, is likely to usher in changes to the central bank with an aggressive easing program. Kuroda is scheduled to hold his inaugural news conference Thursday.
"I hope this opportunity will be seized and that fundamental issues of our economy can be solved," Shirakawa said of his hopes for Kuroda at a news conference later in the day.
Shirakawa was named BOJ governor in March 2008 after the Diet rejected two other nominees. He had served as deputy governor before taking the top slot.
In addition to the task of leading Japan's decades-long battle with deflation, Shirakawa also had to manage the country's monetary policies in the wake of the 2008 Lehman shock, Europe's sovereign debt crisis and the impact of the March 2011 disasters on the domestic economy. Shirakawa also witnessed a revolving door of prime ministers during his term.
Asked to reflect on his five years on the job, Shirakawa said "turbulent" would be the best description of his time in office.
Still, he expressed confidence that the domestic economy remained relatively stable compared to others in the wake of the global financial crisis, and that the BOJ was able to work effectively after the 2011 disasters.
Shirakawa said it was too early to grade his time as BOJ chief and that such an evaluation should be left to a third party.


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Summon Night: Swordcraft Story 2
Review by LordShibas
"Even Better Than The First Summon Night Game"
As the swan song for my GBA collection of games, I chose to play Summon Night Swordcraft Story 2. I was a huge fan of the original Summon Night game for GBA, so I was expecting great things from the sequel. Fortunately, I was not let down at all. Summon Night Swordcraft Story 2 is simply an incredible game that builds and improves on its predecessor in almost every way imaginable.
Summon Night Swordcraft Story 2 is very similar to the first game, and it's almost more of a redux than a sequel. Don't get me wrong, there is a new quest, all new characters, new summon beasts, and all new areas to explore, but the core gameplay is very reminiscent of the first game. Even though it felt very familiar I enjoyed every minute I spent with Summon Night 2, and I would recommend it to anyone that enjoyed the first game, or someone that likes RPGs with a focused story and a good bit of dungeon crawling.
Summon Night 2 takes place in the same land as the first Summon Night, but the story focuses on a different village of Craftknights. While the first Summon Night game had an entire village of Craftknights, the new village (Cliff village) only has a few revered Craftknights. Among these Craftknights are Edgar and Aera Colthearts. You can choose to play through the entire game as either Edgar or Aera, giving you the option of having a male of female lead, much like in the first Summon Night game.
You will also get to choose a Guardian Beast that will act as your magic support during battles. Each of the four Guardian Beasts will have an elemental affinity which separates them from the others. The main character and the Guardian beast will have almost constant interactions with each other, and you will quickly capitulate to having a strong relationship with them.
The actual gameplay breaks down very similar to the first game. You will be exploring dungeons and various areas from a top-down perspective, and once you run into an enemy encounter, the game breaks away to a side-scrolling battle where you have free control over your character. During the battle, you can switch between three weapons that you have equipped and summon your guardian Beast to cast spells.
Prior to venturing into dungeons, you will have the ability to craft weapons from materials you find in the dungeons. The different weapons are the same as before: sword, axe, spear, knuckle, and drill. You can also use your crafting hammer, but there's really no point to it.
The one part of Summon Night 2 that differs from its predecessor is the crafting system. Atlus chose to simplify the crafting system a bit. Instead of having a weapon blue print that requires a certain amount of four different materials, you now only need one base material. Once you have crafted the basic weapon, you can then upgrade it accordingly. This is based on your current craft ranking. The higher your craft ranking the more upgrades you can add to any given weapon. While the new system does simplify the initial weapon crafting, it allows for much more versatility in the end due to the ability to add upgrades. The upgrades can add elemental affinities, special attacks, and durability increases.
Another change to the game is how the durability meter of your weapons is represented. In the first game, your durability meter was reset at the beginning of each battle, and losing weapons due to a lack of durability was never an issue. In the sequel, your durability level does not reset after each battle, so you will need to repair your weapons from time to time. This will make you play a bit more conservatively, but won't affect the game all that much, other than making you head back to repair your weapons every now and then.
Even though I finished Summon Night 2 a short while ago, I've already adjudicated it as being one of my favorite GBA games of all time. The way the story, gameplay, and crafting elements come together makes it a memorable game that held my interest all the way through and assured that I always had something to do or something to strive for.
Graphics 10/10
Summon Night 2 has some of the best looking GBA graphics I have ever seen. It goes without saying that the side-scrolling battles look wonderful, but Atlus really touched up the exploration bits of the game for the sequel. Gone are the days of the first Summon Night game where you had to explore the same dungeon, level after level. Summon Night 2 now has many different areas to explore, most which are outdoors, but a few that are indeed dungeons. The outdoor environments are lush with flora and fauna. One area will have you exploring a forest, the next will have you in an area that resembles a beach, yet the next will have you in an ancient mechanical dungeon with robotic enemies everywhere.
The variety of areas is truly a great improvement over the original game and does a great job of keeping things more interesting than the mundane, multi-floored dungeon found in the first Summon Night game.
Many of the enemy designs are taken straight from the first game, but there are some additions as well. The returning enemies will require the same tactics to take down, but the new enemies will require you to test out all of your weapons on them to see which weapons are the most useful against them. The spells are also somewhat recycled, but again, there are some additions which keep things interesting.
While partaking in the conversations that push the story forward, each character in the game has multiple anime portraits which do a great job of portraying the mood of the characters.
During the battles, even though there will often be quite a few enemies on the screen at once, there will never be any slow down, and things will always move quickly and look beautiful.
Summon Night 2 ramps up the visuals from the first game and it maintains the smooth animation and exciting battle sequences. It's without a doubt one of the best looking GBA games I've ever played.
Sounds and Music 9/10
The sounds and music of Summon Night 2 have also received an upgrade. Some of the same tracks and sound effects are re-used, but there is an increase in music tracks, and things sound a bit clearer overall.
Each dungeon has its own music which properly conveys the mood of the story at any given moment, and while some of the tracks loop over and over, they never seem to get old.
The sound effects are much like the first Summon Night and the different weapons clashing in battle sound great.
Story 9/10
The story in Summon Night Swordcraft Story 2 is very simple, yet gripping and captivating at the same time. It does exactly what the first Summon Night game did and that is it focuses on a few individuals in a single village and spends plenty of time giving each and every character some type of meaningful role to play.
You will spend the most amount of time with your Guardian Beast, and while things between you and your guardian beast will be rocky at first, you will form a strong bond with him or her throughout the game.
Since I chose the male lead in Summon Night 1, I chose Aera, the female lead in Summon Night 2. I chose Dinah as my Guardian Beast. Dinah is a female, Devil creature that has a split personality. She has an evil side and a good side and there is no telling when the good side will show up to completely contradict her evil side's vocations. I highly recommend picking her as your Guardian Beast if you decide to play this game. Her two sides truly make for some laugh out loud moments that make her an incredibly unique character.
The main focus of the game has to do with an ancient seal that has been broken on a creature known only as Goura. It's Aera's job to re-seal the beast and bring peace back to the village. In order to do this, she must collect a series of ancient swords.
The story is a bit more straight forward than the first Summon Night, but it's interesting in itself and there are a few plot twists along the way that will really throw you out of whack.
If there is one thing about the story in Summon Night 2 that I did not like, it was the lack of a Craftknight tournament. In the first Summon Night game, there was a Craftknight tournament that you periodically had to partake in which was really fun, but it was omitted from the sequel. There are also a few translations errors that pop up every now and then, but nothing very frequent.
Gameplay 10/10
What can I say? This game is incredibly fun to play. The crafting, exploring, dungeon crawling, and story elements come together in a unique way that always leaves you wanting more. There is always a bevy of things to do and I often had to force myself to stop playing since there was just so much more I wanted to get done in any given play session.
The crafting aspect of the game makes for almost limitless replay value and there are over 200 weapons to craft, plus upgrades to add to each one.
While exploring the environments during the game, you now have the option of switching between your weapons on the field. Certain weapons can smash certain objects to produce materials for crafting. Tree stumps need to be smashed with axes, weak walls can be broken with drills, knuckles can push large boulders, etc. This also allows for some more puzzle oriented gameplay in the exploration areas, which is a welcome addition.
The random encounter rate is still fairly high, but getting into battles in Summon Night 2 is never really a burden, since you can always use the battles to level up your weapons and raise the level of your character and your Guardian Beast.
So Summon Night 2 plays much like the first game with a few nuances and a more balanced crafting system. It does a great job of blending the different aspects of the game and ensures that you will have rewarding and fun gameplay sessions.
Longevity and Re-Playability 10/10
I was able to get through the main quest in a little under 30 hours, but there are plenty of other things to do in the game. There are weapons to craft, bonus dungeons to beat after the main quest is completed, lots of side quests that the villagers will offer you, and a new game+ feature. I could have easily put another 10 hours into the game.
Summon Night Swordcraft Story 2 is without a doubt one of the best GBA games I have ever played, and I think that anyone who enjoys RPGs should play it. The gameplay is top notch, the facetious story will make you laugh, and the crafting system will cause you to search like mad for crafting materials. I can't recommend this game enough.
Reviewer's Rating: 5.0 - Flawless
Originally Posted: 02/12/09
Game Release: Summon Night: Swordcraft Story 2 (US, 10/17/06)
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text:
The Importance of Monitoring Your IT Ecosystem
"If you can't measure it, you can't improve it."
– Lord Kelvin (1824-1907), British physicist and engineer.
Lord Kelvin, father of the absolute temperature scale now named after him, got it right more than a hundred years ago. Measurement is critical to improvement, whether it be a product or process. Even the management doctrine of "What cannot be measured cannot be managed" has its origins in Kelvin's pronouncement.
Monitoring is a step up from mere measurement. In simple words, monitoring may be described as measurement of parameters and then comparing them against pre-established standards to determine variances, and whether those variances fall within or outside acceptable thresholds.
Today's information-driven organizations face the fundamental challenge of balancing high availability of business-critical information with maintaining its integrity and security. They must do this in spite of an increasingly complex IT environment that often includes traditional physical infrastructure, virtualized infrastructure and cloud computing.
To put things into perspective, Gartner predicts information storage to grow from 40% to 60% annually, while new variants of malware, such as polymorphic attacks that evade anti-virus software and intrusion vectors like web attack toolkits, grow exponentially. However, older standards fall short of recognizing such threats.
This is where the SANS 20 Critical Security Controls (20CSC) come in. As this paper clearly demonstrates, the 20CSC represent "a prioritized baseline of information security and measures and controls." This white paper has impeccable origins. John Gilligan, former CIO of the U.S. Air Force and the US Department of Energy, led the development of this document; it represents a consensus of government and nongovernment experts.
This paper is not merely a recitation of standards; it presents a comprehensive comparison of 20CSC with the ten-year-old Federal Information Security Management Act (FISMA) that has been the gold standard till now. Moreover, it also lays down guidelines for implementation at minimal cost. Download to get free access to this authoritative document.
It's not enough to know what to compare yourself to; you must have the right monitoring tool in hand. That being said, I'm happy to offer you free and exclusive access to Netwrix Auditor. This tool monitors your IT infrastructure in its entirety, because even the smallest IT modifications can have serious repercussions. That's why the product actively assesses your most critical systems 24×7, detecting, capturing and consolidating must-have IT infrastructure audit data to support configuration auditing and answer important questions like:
Who changed what, when and where?
What are current and past configurations?
Click on the link to know more.
By Sourya Biswas


text: 'Sport rules & News' is one of its kinds of application in Android market created by Appz Inventors. It's a must have application on every devices to stay acquainted with latest news, updates, reviews, past results, upcoming events, and lot more happening in the sporting world. From Definition to closing of the game, 'SPORTS RULES & NEWS' comprises of the knowhow of top 12 sports played globally, Vis a Vis - Football, Cricket, Tennis, F1, Golf, Rugby, Basketball, Baseball, Badminton, Volleyball, Table tennis & Hockey. Features: Contains Rules of most popular Sports around the world. Every Rule, Definition and Detail available at your finger tips. Simple navigation . Set any rule as favorite. Brush up memory by taking the Quiz. Share the results and challenge a friend. Highlight: Stay updated with all the recent news related to your favorite Sports. Installation: To install the app, simply search for "SPORTS RULES & NEWS" in the Android Market / Google Play Store. Both Free and Paid version of the app available on Google Play Store. We at 'Appz Inventors' believe that knowledge and inventions are never limited – so we would be excited to receive your suggestion at any point in time. Hope you truly enjoy this application at every sporting ceremony. Best Regards, Appz Inventors


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Gavin DeGraw Speaks Out After Gruesome Attack
Since being brutally attacked just two weeks ago, Gavin DeGraw has kept pretty quiet — and with a broken nose, two black eyes and a mess of bruises and cuts, who can really blame him? But finally, the singer-songwriter has reached out to make a formal statement and let his fans know he's on the mend.
The 'Not Over You' singer told VH1 exclusively:
"Instead of checking in from the tour, I'm writing as I recover at home. I'm feeling much better, but it will take a little bit more time to be back to 100%! I'm overwhelmed with the outpouring of support from my fans, friends, and family. I can't wait to get back out on tour and look forward to seeing you on the road sometime soon. I'll keep you POSTED."
We're elated to hear that DeGraw is getting back to his old self, because he had to pull out of a few high-profile shows with Maroon 5 and Train after the incident. He's scheduled to pick back up on that tour in Columbia, M.D. on Aug. 24.
Additionally, the 'I Don't Want to Be' hitmaker is gearing up to release his brand new album, 'Sweeter,' on Sept. 20. Get well soon, Gav!


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Ford Shelby GR-1
The Ford Shelby GR-1 is a conceptual sports car that was created by Ford. It was first introduced to the public at the 2005 North American International Auto Show. The GR-1 was created with the inspiration from the Shelby brand. It was inspired by and bears resemblance to the Shelby Daytona.
Much of the GR-1 chassis and running gear is based on the Ford Shelby Cobra Concept a modern version of the 1960s original Shelby Cobra, which was presented one year earlier at the 2004 North American International Auto Show. As with the Ford Shelby Cobra Concept, the GR-1 project was led by Manfred Rumpel and developed by Ford's Advanced Product Creation group.
The GR-1 uses a 6.4L all-aluminum V10 engine and utilizes some components from the Ford GT. The GR-1 is officially rated at 605 hp (451 kW) and 501 lb·ft (679 N·m) of torque. It uses a 6-speed manual transmission.
External links[edit]
- Autos y Diseño - Ford Shelby GR-1 concept
- Ford Shelby GR1 Concept with Aluminum Body on Seriouswheels.com
|Wikimedia Commons has media related to Ford Shelby GR-1.


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It's ironic that
on the Lobbyist Registery came into force in the week the long-gun registry debate will come to a head.
The new rules mean that all Members of Parliament, senators and senior staff in the Opposition Leader's Office, House of Commons and the Senate will become designated public office holders, which bars them from lobbying the government for five years after they leave their post.
So, the lobbyist registry is good because it registers law abiding citizens who happen to be politicians or political staffers, and therefore can't be trusted. But the gun registry is bad because it registers law abiding citizens who like hunting ducks but are the salt of the earth.
When you think about it, that sounds about right.
National Post


text:
Four sought in attempted robbery at NC State
Posted July 14, 2012
Raleigh, N.C. — North Carolina State University police are on the lookout for four men in a silver sedan who tried to rob a group of students early Saturday.
Around 2:45 a.m., police said, four students were walking on campus along Dan Allen Drive, near the West Dunn Building, when they were approached by the men in the sedan. The would-be robbers implied that they had a gun and told the students to empty their pockets.
When the students refused, the men drove away.
No one was injured and the victims didn't report seeing a weapon.
Anyone with information is asked to call campus police at 919-515-3000.


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National Down Syndrome Society8 E 41st Street, 8th FloorNew York New York 10017800-221-4602[email protected]
I have Down syndrome and this is my great story. My name is Olivia Rachelle Brosseau and I am nineteen years old. I live in a small town named Glover, Vermont. Last year I graduated high school from Lake Region union high school in Barton, Vermont. If I could tell you one thing about myself it would be that I am human and I should feel loved and treated as an equal human being. I'm making a name out for myself. I'm making a difference in the lives of many people. I am blessed to have an extra chromosome; god put that in me and I love it. I'm not letting the doctors and the people who have doubts about Down syndrome get to me; I'm having the last laugh, I have accomplished so much throughout my life. I'm not letting them put doubts and limits on me, that don't work for people. I'm in college in Community College of Vermont in Newport, Vermont and I am working to get my degree in human services. So I can help people with disabilities, I'm going to have a conference center in my future house so I can teach people with disabilities basic life skills. I will have a parent support group and student support group, so they can express their concerns and problems and I will help them with guidance and support and I will get them resources as well. In a few months later in the future, I will have a toddler and baby playgroup and support system, and it would be integrated as well with kids with no disabilities. This is my dream. As well spread awareness of Down syndrome and the misuse of the "r word," which is retard or retarded. I hate those words, and I take immense offense to it. I see it every day and hear it and I break down and cry. Those words describe so many people that I care about and love, it has to stop. For centuries after centuries and decades after decades, people have said the r word and it has to end right now. At the end of junior year and the beginning of senior year, everybody at my high school was saying the r word, in front of me , it wasn't direct , but indirect hurts a lot too, it's like a sucker punch to the stomach. People have to wake up and realize that we need to be treated the utmost respect. RESPECT – that's the new r word. I don't care if the r word is politically correct or not and using it the right way even hurts too. It doesn't matter how you use it, it's offensive, discriminatory, you're talking about a person. What if you or someone you know, or a daughter or son, nephew, cousin, or niece have an disability and people come up to you and say the r word, how would you feel?
[email protected]
National Down Syndrome Society, 8 E 41st Street, 8th Floor, New York, New York, 10017Copyright © 2012 National Down Syndrome SocietyPrivacy Policy | Terms and Conditions


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Join our customer services director Charlene Kane for a LIVE Facebook chat about our onboard menu on Tuesday!
Here at Monarch we're always looking for ways to get to know you better, so we can tailor our services to your needs and make improvements. Many of you are now on Facebook and some of you even 'like' our page and post regularly about your inflight experiences. We've learned a lot in the last year by listening to your thoughts and feeding them back to various departments to improve your experience.
One of the most topical issues we've discussed this year is our onboard menu. The new products have as always been decided based on your feedback and a little bit of clever market research by our inflight catering team. The next menu update will be coming up in a few months and to ensure this is even more to your tastes, we'd like to talk turkey with you!**
Special event: Facebook chat about onboard menus
Lead by: Monarch Customer Services Director Charlene Kane
Date: Tuesday 29 May
Time: 12:30pm-1:30pm
Location: The Wall at www.facebook.com/monarch
Here's how it works
- Help us to prepare by sending your questions about our onboard menu by email to firstname.lastname@example.com by Sunday 27 May (not compulsory)
- Equally, feel free to pop a question in the comments below
- Meet us at www.facebook.com/monarch on Tuesday 29 May between 12:30pm-1:30pm.
- Watch our for our post announcing Charlene's ready to chat.
- When you see this announcement, add your question as a comment on this post.
- Please note: Please don't post other separate questions relating to the chat on our wall as it's rather easy to confuse us!
What are we going to be talking about?
We don't like to put you on the spot, so here are a few ideas to get the creative juices flowing and your thinking cap thinking, before the live event:
- Do you like certain elements of a breakfast/lunch/dinner, but perhaps not others so much?
- Do you prefer a certain snack, or wish we stocked a different brand of soft drink (the old Pepsi/Coke challenge!)
- Do you like to eat a meal onboard or prefer to grab something before you fly?
- Do you wish we would do something different in general? Bring your ideas along!
Contingency plans & community rules
- This is a great opportunity to tell Charlene what you think of our food. Please try to offer constructive feedback and explain what it is you like or dislike so that we can make changes accordingly. We will seriously consider all reasonable ideas and requests, but we can't promise we'll be able to implement all of them
- Please stick to the topic because in the limited time we'll have, we won't be able to answer anything off topic
- Charlene will try to answer as many on topic questions as possible, that we receive by 1:30pm. If she can't answer everything, we'll answer as many as we can later here on our blog
- Charlene will try to answer your questions personally, but if we receive multiple questions about roughly the same topic, we'll try to answer them all together as a theme
- Please only post your question once – we'll see it there even if we don't answer it immediately. We'll do our best to pick it up on the blog later if there's not time to reply
- Please stick to the normal rules of friendly engagement, i.e. be friendly to other people in the discussion even if you disagree with their point of view, use clean language and so on. Our full 'safety card' gives some overall guidance
- We are hoping for a lively, but friendly, debate. In the unlikely event of a "troll" turning up, we reserve the right to delete posts in order to minmise offense to other participants. We're not in the business of deleting posts we don't agree with
**Turkey isn't on the menu at the moment. It could be, but it's just an expression. Sorry!
I think, on most flights to European destinations, eating is just 'boredom eating' anyway, and not always really necessary. Maybe, if that gap needs to be filled, sandwiches or baguettes would be more acceptable than a more conventional meal.
You could also offer a variety of fillings, so that those with allergies or dietary preferences could make a choice without having to book beforehand
Hi Keith, thanks for your feedback. I think you may have a point but it's also possible that because passengers are booking their meals in advance, rather than boredom eating, it's just something they like to enjoy as part of their flying experience. We do offer snacks onboard for those who feel peckish and/or want something to help pass the time – these are great if you're not really into planning your meals long in advance of travel!
I was just lurking here, because I haven't flown with Monarch since 2005 (Crete). There's a note in my journal that I didn't eat on the aircraft, because I wasn't very hungry, having had a good breakfast at Gatwick; I didn't really fancy anything that was on offer … and I could smell the preservative from where I sat!
Hopefully, things have improved … ????
Hi Keith, we'd certainly like to think so! I suppose the only way to find out is to order a meal and decide for yourself. Would be interested to hear your feedback!
This isn't about in flight food sorry but i thought it was a great opportunity to ask if monarch would consider putting flights on from belfast to bodrum turkey? Thomas cook/Thomson have a stranglehold on the market and we have no choice but to fly with them (property owner in bodrum). a bit of competition wouldn't go amiss plus we pay hugely inflated prices because of lack of competitors!!
Hi Kim, I don't know if that's under consideration but if/when a new route is developed we'll announce it on our website and via social media. Thanks for your question.
Food has always been ok, but bigger portions would be much better!
We have reviewed the portion size and it is slightly bigger than before. Glad to hear you like it so much that you want more of it! Charlene.
I would love it if airlines served fresh fruit/fruit salads even healthier foods on their flights! It's so important to keep hydrated and fruit is so refreshing on a flight. Salty snacks make you bloat and dehydrated. So, is there any chance that Monarch will sell fruit salads and healthier food on board in future, please?
Hi Dougie, this is definitely an idea for the future. We'd have to review some of the equipment we have onboard to keep it fresh. Thanks for your question! – Charlene
I generally always fly monarch and find the service very good, except for the food!
We (pre)ordered food for our return journey as it was a late flight and we would be unable to eat when we arrived back in blighty.
Nowhere on the flight details could you specify any allergies. A member of our group has a SEVERE allergy to mushrooms!!
We asked the onboard crew what ingredients was in the food they were serving. They couldn't tell us, as the only way to get that information was on the Monarch Intranet (which is unsuprisingly unavailable whilst up in the air!!)
We boarded the flight and we were served our food. We discovered the meat based evening meal was a beef stew, and contained mushrooms. So that particular member avoided eating that and was supplied with a replacement meal: the vegetarian option… it was only after a few bites of that, that mushrooms were also discovered in that. This particular member then had to dose up with medication just to ease the symptoms! It didn't make for a very good journey home!
Please can you improve on this by at least listing the ingredients in each meal and provide a facility for people to declare allergies to peanuts, mushrooms etc. etc. ?
kind regards
Hi Martin, I think we discussed this on Facebook but just to reiterate, that's an unfortunate situation and we would like to avoid a repeat of that. We're looking at ways to make this information more visible to customers and our crew. – Charlene
Why have you deleted my comments on both blogs?
Hi Tony, your comments weren't deleted, they were in a queue for moderation. I've answered your previous post. Thanks.
Food…what food. We are flying "Premium" to Sanford on Thursday 31st May. We just rang the customer services (Monday 0920hrs) to request vegetarian and were told that we can't order vegetarian as we have to do that 5 days before departure ! Where did it say that in the booking page. Too bad if you book last minute. Even more amazing we can't order vegetarian on our return leg in two weeks time because that had to be in five days before the outbound flight. So we have to take sandwiches on board. So much for Premium service and price! Not a great start is it Mister George, lets see if you listen to your customers now?
Hi Tony, thanks for your post. I have passed your comments on to our customer services team and I believe they are trying to contact you by the email address you registered on this blog with.


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The prescription for keeping unused drugs off the street
Fri, 25 Oct 2013 09:57:58 GMT —
The Michigan State Police is joining forces with the Drug Enforcement Administration and other agencies for National Prescription Drug Take-Back Day.
The day is set aside to give people a chance to dispose of unwanted and unused prescription drugs.
All 29 Michigan State Police posts will take part in the one-day 'take back' effort from 10 a.m. until 2 p.m. Saturday. No liquids, inhalers, patches, or syringes are to be accepted. The service is free and anonymous with no questions asked.
"Our 29 post across the state will serve as drop-off points allowing citizens a safe and confidential way to dispose of expired, unused and unwanted prescription drugs," said Col. Kriste Kibbey Etue, director of the MSP. "The Michigan State Police is pleased to yet again partner with the DEA to prevent pill abuse and theft by helping residents rid their homes of potentially dangerous prescription drugs."
Rates of prescription drug abuse in the U.S. are alarmingly high, as are the number of accidental poisonings and overdoses due to these drugs. Studies show that a majority of abused prescription drugs are obtained from family and friends, including from the home medicine cabinet. In addition, Americans are now advised that their usual methods for disposing of unused medicines-flushing them down the toilet or throwing them in the trash-both pose potential safety and health hazards. MSP collection sites can be found below.
Additional collection sites across the state can be found by
clicking here
MSP collection sites include the following:
Alcona County
Alpena County
Montmorency County
Oscoda County
Presque Isle County
Alpena Post
3283 West Washington Alpena, 49707
(989) 354-4101
Chippewa County
Luce County
Sault Ste. Marie Post
Sault Sainte Marie, 49783
(906) 632-2217
Clare County
Isabella County
Mecosta County
Osceola County
Mount Pleasant Post
3580 South Isabella Road
Mt. Pleasant, 48858
(989) 773-5951
Mackinac County
Schoolcraft County
Saint Ignace Post
St. Ignace, 49781
(906) 643-7582
Lake County
Mason County
Newaygo County
Oceana County
Hart Post
3793 West Polk Road Hart, 49420
(231) 873-2171
Antrim County
Charlevoix County
Cheboygan County
Emmet County
Otsego County
Gaylord Post
563 South Otsego
Gaylord, 49735
(989) 732-2778
Crawford County
Kalkaska County
Missaukee County
Roscommon County
Houghton Lake Post
9011 West Lake City Road Houghton Lake, 48629
(989) 422-5103
Benzie County
Grand Traverse County
Leelanau County
Manistee County
Wexford County
Cadillac Post
7711 South US-131
Cadillac, 49601
(231) 779-6040


text:
»Chemistry and Biochemistry
» Minor in Chemistry
The chemistry minor is an excellent option for majors of other science fields to add to their credentials if they wish to apply to a pre-professional school, such as medical school, or if they want to teach secondary school chemistry along with biology, physics or mathematics. It's also a valuable complement to a major in business administration or marketing.
Required Courses
CHM 211, 212 Chemical Principles I and II
CHM 220 Advanced Chemical Principles
CHM 311, 312 Organic Chemistry I and II
Plus two additional course credits, including a minimum of one lab
Students should consult with department faculty for course selection to ensure that the laboratory requirements are met. A grade of C or higher in each course is required.
Elmhurst College • 190 Prospect Avenue • Elmhurst, Illinois 60126-3296 • (630) 279-4100
Undergraduate Admission • (630) 617-3400 • (800) 697-1871 • email@example.com
School for Professional Studies • (630) 617-3300 • (800) 581-4723 • firstname.lastname@example.com
Elmhurst Learning and Success Academy Admission • (630) 617-3752 • email@example.com


text:
Frequently Asked Questions: Search
Your FAQ Results for Tag: "macintosh"
- How do I change the login icon on my Mac?
- I am a Mac user, why do you want to know what local administrative account I use?
- I don't want to log into my Mac - I like it the way it is now.
- I have an iMac and the techs turned off wireless, why?
- I have local accounts on my Macintosh for my students. Can they still use them?
- I thought you would never ask me for my password, why do you want to know what local account I use?
- My students and I share files on my Mac. Can we still do that?
- Why does my Mac prompt me for "lpadmin" credentials when I try to add or remove a printer?


text:
Monetary Policy Effects on Financial Risk Premia
The effect of monetary policy on financial risk premia is analysed in a simple general equilibrium model with sticky wages and an optimising central bank. Analytical results show that equity risk premia and term premia are higher under inflation targeting than under output targeting, and that inflation risk premia are higher for policies that strike a balance between output and inflation stability (and achieve a social optimum) than for policies that target only one of them.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
|17 pages
|Date of creation:
|Nov 2006
|Contact details of provider:
| Postal: Dufourstrasse 50, CH - 9000 St.Gallen
Phone: +41 71 224 23 25
Fax: +41 71 224 31 35
Web page: http://www.seps.unisg.ch/
More information through EDIRC
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Hansen, Lars Peter & Jagannathan, Ravi, 1991.
"Implications of Security Market Data for Models of Dynamic Economies,"
Journal of Political Economy,
University of Chicago Press, vol. 99(2), pages 225-262, April.
- Lars Peter Hansen & Ravi Jagannathan, 1990. "Implications of security market data for models of dynamic economies," Discussion Paper / Institute for Empirical Macroeconomics 29, Federal Reserve Bank of Minneapolis.
- Lars Peter Hansen & Ravi Jagannathan, 1990. "Implications of Security Market Data for Models of Dynamic Economies," NBER Technical Working Papers 0089, National Bureau of Economic Research, Inc.
- Sellin, Peter, 2001. " Monetary Policy and the Stock Market: Theory and Empirical Evidence," Journal of Economic Surveys, Wiley Blackwell, vol. 15(4), pages 491-541, September.
- Boyle, Glenn W & Peterson, James D, 1995. "Monetary Policy, Aggregate Uncertainty, and the Stock Market," Journal of Money, Credit and Banking, Blackwell Publishing, vol. 27(2), pages 570-582, May. Full references (including those not matched with items on IDEAS)
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text:
Aries | March 21 to April 19Your lifelong love of all things zombie becomes a definite liability when former president Ronald Reagan mysteriously returns to life and is told that you wouldn't mind if he stayed at your place.
Taurus | April 20 to May 20You have the wisdom of Solomon, but the sensationalist jerks on the news insist on referring to you as that monster who chopped all those poor children in half.
Gemini | May 21 to June 20Your outspoken criticism of your superiors will lead to your transfer to a combat posting in the Middle East, something you didn't know the manager of an auto-parts store had the authority to do.
Cancer | June 21 to July 22The great white shark is brutally tenacious in pursuit of its prey, as you will discover after changing your name and moving to land-locked San Antonio.
Leo | July 23 to Aug. 22If you're reading this, Leo is dead. It's been lying about the dark stranger all along. You'll find the money hidden behind the Horsehead Nebula.
Virgo | Aug. 23 to Sept. 22You'll fall under the influence of a drug that makes you think you can fly, but to the dismay of the people beneath your window, it actually makes you invisible.
Libra | Sept. 23 to Oct. 22You're someone who calls 'em like he sees 'em, which is a problem for a constantly hallucinating stutterer like yourself.
Scorpio | Oct. 23 to Nov. 21A combination of mistakes involving geography, bravado, and making promises while drunk will soon result in you going over Sioux Falls in a barrel.
Sagittarius | Nov. 22 to Dec. 21A new international economic study indicates that tropical fruit and luxury automobiles have been overtaken by your overseas hate mail as America's number-one import.
Capricorn | Dec. 22 to Jan. 19Your constant search for inner beauty leads to six months of pain when you pay an expert to tattoo the Last Supper on your heart, lungs, and renal system.
Aquarius | Jan. 20 to Feb. 18It's been exhausting, but personally befriending everyone in the entire nation will pay off next Thursday when jury selection for your insurance-fraud case proves impossible.
Pisces | Feb. 19 to March 20You like to think you're passing a lifetime's worth of wisdom to a younger generation, but the rest of the world thinks of you as a kitchen-counter installer with a DSL connection.


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It's a Wrap! Custom Creations designs unique items for your special events! We offer Personalized Wrappers for all occ... Read MoreRead More asions including Birth Annoucements, Baby Showers, Wedding Favors, Bridal Showers, Birthday Party Favors, Holiday Treats, Graduations, Prom, Homecomings, Reunions and even Business Promotions!
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Years ago, I recall having a friendly conversation with another attorney in Connecticut where the topic turned to the notion of "At Will" employment. When we couldn't settle on an answer, we moved on to talking about whether the Hartford Whalers would ever come back. I think we had a better answer for that question:… Continue Reading
Tag Archives: at will
From the Archives: Offer Letters in ConnecticutPosted in Human Resources (HR) Compliance, Wage & Hour
As I take a few days off, here's a post from WAY back in 2009 about offer letters that you may have missed. With employers doing more hiring in 2013, it takes on added relevance. In my series of the "basics" of various employment laws (see prior installments here,here and here), this week the topic is offer… Continue Reading
They're Alive! At-Will Disclaimers Are Alive! (Sort Of. Maybe.)Posted in Highlight, Human Resources (HR) Compliance, Labor Law & NLRB
Remember earlier this year when the NLRB was hinting that certain at-will disclaimers (you know, the type of language in offer letters that says that the employee is at-will and can be fired for any reason or no reason at all) might be illegal under a new reading of applicable labor law? The issue for… Continue Reading
Five Things To Know About Paid Sick Leave, NLRB and Other New DevelopmentsPosted in Highlight, Laws and Regulations, Legislative Developments, Social Media, Wage & Hour
At yesterday's labor & employment law seminar, we had both Heidi Lane, a Prinicipal Attorney with the Connecticut Department of Labor, and Jonathan Kreisberg, Regional Director of the NLRB's Hartford Office, speak to attendees about the latest developments under both Connecticut and federal law. But for those who couldn't make it, here are five notable things they discussed: 1)… Continue Reading
Court: Statement by Supervisor Regarding "Satisfactory" Progress on Performance Does Not Change At-Will EmploymentPosted in Human Resources (HR) Compliance, Litigation
Earlier this week, I highlighted one holding from a new case from the Connecticut Appellate Court that will be released next week. Another portion of the case dealt with interaction between the employee and the supervisor. In the case, the plaintiff alleged that she had been told by her supervisor that, after she had been… Continue Reading
Guest Post: NLRB Acting General Counsel Addresses At-Will Disclaimers and More at CBA Annual MeetingPosted in Class Actions, Highlight, Labor Law & NLRB, Social Media
On Monday, the Connecticut Bar Association held its annual meeting. Lots of labor and employment law topics were covered, some of which I missed. I've asked one of my bar colleagues, Rita Trivedi — who will be a Teaching Program Fellow at Columbia Law School in the fall — to share her insights on the… Continue Reading
In Drafting Employment Law Contracts, Precision and At-Will Disclaimers MatterPosted in Highlight, Human Resources (HR) Compliance, Litigation, Manager & HR Pro's Resource Center
Suppose that, after you've employed a worker for a year or so, she asks you for a raise. She doesn't ask about any guarantee term for employment but you come back and give her a 36 month time frame for her salary going forward. You draft an employee "Employment Agreement" that says ''[t]his will cover the… Continue Reading
"For Any Reason or For No Reason" – The Language of an At-Will Employment RelationshipPosted in Human Resources (HR) Compliance
Take a look at your employment-at-will language right now in your employee handbook or offer letter. (I'll wait; if you can't find it, you've got larger issues than the one I'm about to discuss). It probably says something like this: Your employment with the Company is on an "at-will" basis. This means that you have… Continue Reading
The Basics: Offer Letters of Employment in ConnecticutPosted in Human Resources (HR) Compliance, Wage & Hour
Continuing the summer series of "basics" of various employment laws (see prior installments here, here and here), this week the topic is offer letters. Specifically, at the time of hiring an employee, does Connecticut require any documentation be provided to employees? The answer is yes. Perhaps not in the form of an "offer letter" but… Continue Reading
Court Denies Summary Judgment to Employer Who Claimed Employee Improperly Used Employee Discount for RelativesPosted in Discrimination & Harassment, Human Resources (HR) Compliance, Litigation
Going to a trial with an employment discrimination case is expensive. Which is one reason why many employers will ask the court to dismiss a claim before trial using a process known as "summary judgment". But a recent federal court case illustrates the difficulty that employers still have in getting courts to grant summary judgment… Continue Reading
Court Examines The Parameters of the Public Policy Requiring Employers to Provide a Reasonably Safe WorkplacePosted in Human Resources (HR) Compliance, Litigation
An employee who contended that he was fired after complaining about a physically threatening co-worker cannot bring a wrongful discharge claim, in a decision released by the Connecticut District Court. The case, Ferrer v. T.L. Cannon Management Corp. (download here), does suggest, however, a way for employees to bring such claims in the future — with some artful language in the… Continue Reading
Legislative Update: February 5th Hearing Set on Bills Relating to FMLA Leave, Termination Notices, Paid Sick Leave and Workplace BullyingPosted in Legislative Developments
The Connecticut Labor & Public Employees Committee is now scheduled to hold a hearing on various labor bills of relevance and importance to employers in Connecticut. Some are re-hashes of bills raised last year, but others, including amendments to the state's FMLA laws are new. The hearing is scheduled for February 5, at 2 p.m…. Continue Reading
Corrective Action Memorandum Not a Contract, Says District CourtPosted in Litigation, Wage & Hour
UPDATED 2/10/09 Sometimes, by coincidence, two unrelated decision get released in close proximity to one another that they bring some greater clarity to the law. Yesterday, I discussed a Connecticut Superior Court case that found that certain discussions did not create an employment contract and that the employee was properly classified as "at-will". Earlier this… Continue Reading
"Probationary" Periods for New Employees May Put At-Will Employment At RiskPosted in Human Resources (HR) Compliance, Litigation
Connecticut is an at-will employment state, meaning that employers can terminate an employee's employment for any reason at any time, with or without cause. Employees are also free to leave their jobs at any times. There are exceptions, of course, to that general rule. But overall, when an employer's offer letter to an employee confirms… Continue Reading
Updating Employee Handbooks — Even Road Signs Need to be ReplacedPosted in Human Resources (HR) Compliance
Next time you're driving on the highway, take a look at the road signs. Not for what they say, but how they say it. Are they new or worn? Easy to read or difficult to see? Straightforward or confusing? If you drive down I-95 around Fairfield and Westport, you'll notice something different lately. The signs… Continue Reading
Appellate Court Affirms Finding of At-Will EmploymentPosted in Litigation
The Connecticut Appellate Court today unofficially released a Per Curium decision that affirms the general principle that a contract for an indefinite term is a contract for at-will employment, even in the apparent absence of express terms. In Ward v. Distinctive Directories, Inc., (officially released on October 23, 2007), the Court was asked to review… Continue Reading
Court Oks "Firing" a Not Yet Hired "Employee"Posted in Litigation
"You're hired. No wait, you're fired." That's essentially what happened in the case of Petitte v. DSL.net, a decision recently handed down by the Connecticut Appellate Court. The Appeals Court rejected Mr. Petitte's claims that the company should be estopped from firing him. The background is fairly straight-forward: Mr. Petitte applied for a position as… Continue Reading


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Implantation bleeding?
I had sex exactly 15 days ago, my birth control failed and I did take plan b several hours later the same day. I was ovulating the time we had sex (days 13 and 14 of my cycle :|) he did cum in me. I have been sick for the past week or so and not feeling myself. I continued to take my birth control pills, I got to the sugar pills and didn't have any signs of my period until the last day I got my "period". Normally, I have cramps 3-4 days before I get my period but this time I had nothing. The blood is a light red/dark pink and very light. I had a tampon in all night and didn't even fill half of it. I am still nauseous, have headaches, backaches and small clots from my "period" normally my bleeding would be heavy by now but it isn't at all. Does this sound something like implantation bleeding?
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** my boobs have also gotten bigger and are very sore..my bras are no longer fitting as well and people are noticing, everyone who I'm around says "you're pregnant." I just can't tell if this is a strange period or I am really pregnant.
by Ruby Member on Sep. 24, 2013 at 7:53 PM
I guess it could be, but my implantation bleeding was very slight. A tampon would have been torture/dry.
The only thing you can do is test.
I never got implantation bleeding
I never got implantation bleeding
This might be a little much but for the most part they are very dry..keeping them in for about 4-6 hours and they're not even half full. But I kept one in almost all day and it was just about full. Normally on my period I can't keep tampons in for more than about 2 hours or so and then they're full. I don't know if this is messed up because I took plan b but I have a lot of other signs right now.
Quoting Pnukey:
I guess it could be, but my implantation bleeding was very slight. A tampon would have been torture/dry.
1-5 of 5 replies
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GAINESVILLE — Chandler Parsons did everything possible to return to Florida's lineup Thursday night, including intensive rehab that lasted into the wee hours of the morning with trainers trying to repair a deep thigh bruise he suffered two weeks ago.
A senior with two home games remaining, Parsons desperately wanted to get back — now. And so he did.
With No. 13 Florida trailing Georgia by seven at halftime, Parsons sparked the Gators with four of his 16 points to open the second half, as Florida rallied for a 71-62 victory in front of 12,013 at the O'Connell Center.
The Gators (22-5, 11-2 SEC) clinched the No. 1 seed in the East in the SEC tournament that begins March 10 in Atlanta, and will win at least a share of the overall SEC title. The Gators have won six consecutive games, and nine of their past 10. And they aren't satisfied, with a game at Kentucky on Saturday up next.
"You know what, we never once talked about winning the East," said Parsons, injured on Feb. 12 in a collision with teammate Alex Tyus. "We have bigger goals than that. We want to win the entire conference, and we understand that we needed to come in here and take care of Georgia, and now we're on to Kentucky.
"It's definitely not going to come easy for us, but we were ready to take on the challenge."
Of the injury, Parsons said: "I couldn't really feel it."
With a 52-51 lead with 7:31 left to play, Florida sophomore guard Kenny Boynton hit three consecutive 3-pointers, then had an assist to Tyus on a fastbreak as part of an 11-2 run that gave the Gators a 63-53 lead. Georgia (18-9, 7-6) couldn't come back.
"After the first one, I knocked down the second, and after the second one, it just felt perfect," said Boynton, who had a team-high 18 points.
Florida scored 23 points off Georgia's 13 turnovers. The Gators had just two turnovers in the second half (five for the game) and shot 45.5 percent from the field.
"Florida just outworked us in the second half," said Georgia guard Travis Leslie, who had a game-high 20 points. "They beat us on the boards, they just fought hard and came back to get the (win)."
For Florida coach Billy Donovan, it was a bonus seeing Parsons return and play a valuable role after struggling with his injury.
"What he did to get himself back was unbelievable," Donovan said. "I would say legitimately he probably got five hours of training a day. He worked around the clock to get himself ready. I appreciate him working that hard because he really helped us."
Antonya English can be reached at firstname.lastname@example.com.


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As usual, the massive Kids Exchange consignment sale at the N.C. State Fairgrounds heralds the beginning of children's consignment sale season.
This huge sale featuring thousands and thousands of items is open to the public from 9 a.m. to 6 p.m., Friday; 9 a.m. to 5 p.m., Saturday; and 10 a.m. to 5 p.m., Sunday. Some items are half off on Sunday.
Consignment sales like the Kids Exchange offer gently used and sometimes new children's clothes, toys, gear and other items at inexpensive prices. We have about 40 in the region, running through October.
These are fantastic opportunities to fill your kids' closets with the clothes and items they'll need for the fall and winter season for much less than you'd pay at a store. Halloween costumes, winter coats and boots and similar items will be some of the popular finds.
For information about the region's other sales, check our database. Some sales are just starting to schedule their fall events. And for more about the Kids Exchange, click here. From now until the end of the season, I'll have a post each week announcing that week's sales, if there are any.
Happy shopping!


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COVINGTON, La. (CBS/AP) Meet Jennifer Gille.
Hi, Jennifer!
Police in Louisiana say the 29-year-old had a great idea on how to get to Michigan from Louisiana: strip naked in the back seat of a cab and demand that the cabbie take her to her home state of Michigan.
As that's a pretty far drive - over a thousand miles, according to Google Maps - the cab driver refused.
Did Gille give up?
Apparently not.
Covington Police Capt. Jack West told The Times-Picayune that the driver went to a police station for help when Gille refused to leave the vehicle, and while the man was inside the station Gille stole the cab.
Police say they found the cab parked about a block away and Gille was still naked. Gille was booked on charges of unauthorized use of a movable vehicle and obscenity.
She was released from jail late Tuesday on a $75 signature bond.
The Trip Gille Allegedly Wanted to Take:
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KUALA LUMPUR: A trip to a shopping centre turned sour for a woman, who claimed she was punched in front of her children following an accident last Monday.
Housewife Wong Lai Yee said she was in her car, turning into Ampang Point, when her vehicle knocked against a car coming from the opposite direction.
She claimed that when she got out to check the damage, the other driver started shouting at her.
"He was yelling at me, claiming that I'm being kurang ajar (rude)," said Wong during a press conference at the MCA Public Services and Complaints Department here yesterday.
Wong, 43, said she was ready to pay compensation for damage on the other car as it was her fault, adding that the paintwork was only "a little chipped off".
"I was upset when he started yelling so I replied – 'who is the one being kurang ajar now?'," she said, adding that the man then punched her on her right arm.
Wong said when she told her son, who saw the incident with her younger daughter, to quickly take a photograph, the man threatened him.
"He threatened to beat my son up and demanded that he get back in the car," she said, adding that the man then kicked her Hyundai Sonata car before driving off.
She claimed that the kick caused a dent to her car.
Wong subsequently lodged a report at the Ampang police station.
Department head Datuk Michael Chong said although road bullying was a serious matter, the number of incidences in the country was still under control.
Read the full article:
http://thestar.com.my/news/story.asp?fi ... sec=nation


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Black Friday Sale Event at The Wooden Indian Ltd.
November 29, 2013
The holidays have begun at The Wooden Indian Ltd with our Black Friday weekend Sale. Our holiday selections are beautiful, from the Waterford Snowflake collection, Vietri Christmas, Byers' Choice and so much more. Start your Christmas shopping early and take advantage of the great sale. Beauregard is waiting by the front door to greet you.
Calendar of Events
- Today
- Friday, September 22
- Saturday, September 23


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As part of an Ohio prep wide receiver's top three, Iowa State hopes to get its foot in the door within territory usually reserved for Big 10 programs. One of the first steps will be making a favora...
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I've been a fan of debunking commonly-held feline myths, but today I've got a story that actually adheres to two well-known cat proverbs: curiosity killed the cat, and cats have nine lives. The two often go hand-in-hand, as it's a cat's never-ending curiosity that usually gets it into situations it narrowly escapes.
Now the New York Post has an article about a cat in the Big Apple who worked at saving one of its lives by fighting another cat myth: that cats hate water. Nazzaning, a six-year-old Turkish Van, found herself partially paralyzed by a spinal cord injury. Her owner Florence Rostami originally thought Nazzaning had a broken paw, but learned at the veterinary hospital that the cat had actually somehow injured her spinal cord.
Then Nazzaning's doctors recommended a very unusual treatment, or at least, one many would consider crazy for a cat: physical therapy in water. Rostami was willing to try anything to help Nazzaning, so they proceeded to the Water 4 Dogs animal clinic in Lower Manhattan.
Sessions started off with therapist John Larson carrying Nazzaning through 92-degree water. The warm water temperature keeps the animals comfortable, and Larson carried the cat to keep her from getting her head wet, something that he feared might cause Nazzaning to flip out.
Hydrotherapy for such injuries is usually only recommended for humans or dogs because of most cats' aversion to water. The article does not specify why Nazzaning's vets recommended it for her. Perhaps they thought it was her best chance, or perhaps it was because of her breed.
Of all the feline breeds, Turkish Vans are those cats most associated with water. Turkish Van site swimmingcats.com says that while not all Turkish Vans want to go for a dip, instead preferring just to pop in and out of the shower or play in water bowls, the breed is known for enjoying swims in shallow water.
So Nazzaning may very well have her heritage to thank for looking after one of her nine lives. But even more she has to thank her owner, Rostami, for sparing no expense to look after her.
As one may have guessed, pet hydrotherapy doesn't come cheap. Rostami paid $160 for each hydrotherapy session. Between that and the overall vet bills, Rostami says the cost is comparable to those of her own physical therapy sessions for a major foot surgery she had months before.
But we animal lovers around here on the pets blog certainly sympathize with Rostami's willingness to do anything to help her pet. And the expense has certainly paid off; now Nazzaning is back to dashing around the house just like she always did.
In addition to being a heartwarming animal story, Nazzaning's tale also works as some good pet health information. I'm glad to know more about the options available should my cat ever injure himself in such a way; and as I've mentioned before, I'm far more likely to get kitty Cole in the water for hydrotherapy than my dog Chihiro.
Related Articles:
Diary of a Cat Care B&B: Three Cases for Keeping Cats Indoors
Health Benefits of Hot Tubs and Hydrotherapy


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The game was developed by Empire Oxford from the classic Tecmo arcade title and saw off competition from the likes of Catan, Pinball FX, 3D Ultra Minigolf Adventures, Centipede & Millipede and Worms.
Empire is now lining up its second title for XBLA, namely Speedball II: Brutal Deluxe. The Bitmap Brothers' classic sold over two million units on its original release; the new High Definition version will feature more teams and downloadable content.
"We are pleased to be bringing this all time classic to Xbox Live Arcade," said Empire's CEO Ian Higgins. "With its brutal and addictive gameplay, and the ability to play multiplayer over Xbox Live, we are sure this will be the definitive version of Speedball."


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I was born and raised in Vacaville and moved away after I graduated from high school. I decided to move back to my beloved hometown after I retired. After being away for more than 30 years, I am troubled by the changes I see.
Vacaville has grown to almost 100,000 residents and faces the problems that all urban cities experience. Some of the issues that must be addressed include homelessness (there isn't even a place for someone to shower), gangs (about 400 members), unemployment, changing demographics and protection of open spaces.
When I attend City Council meetings and these issues are brought up by concerned citizens, the council members brush the problems aside and think in a small-town mentally. Representatives who don't listen -- how can they truly represent us?
I've attended various City Council forums to listen to the five candidates running for office, and all but Deloris Roach support the status quo. When asked about the development at Lagoon Valley, Ms. Roach was the only candidate willing to re-examine the proposed plan.
She believes solutions include investments, such as activities for youth and engaging teens in the political process -- what kind of city do they want Vacaville to be? After all, our children are the future.
She will hold community meetings in neighborhoods to provide equal access and the capacity to use knowledge on which all decisions are made. Ms. Roach supports development in the lots available and preserving open space. She understands the needs of our growing senior population and has ideas on how to ensure that there are livable-wage jobs that are, at the same time, environmentally sound.
Issues come and go -- at the core, values are important. Deloris Roach is committed to equally protecting and equally empowering all of the citizens of Vacaville.
Debra Boivin


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More aggressive treatment warranted in patients with metabolic syndrome
Early online publication: Tuesday, September 5, 2006
More aggressive treatment with statins is necessary to lower LDL (low-density lipoprotein) cholesterol in patients with coronary heart disease and metabolic syndrome, a syndrome composing of three cardiovascular risk factors (see Editor's Notes) according to an Article published online today (Tuesday September 5, 2006) by The Lancet.
The Treating to New Targets (TNT) study was a prospective, double blind, parallel-group trial which was done at 256 sites in 14 countries between 1998 and 2004, with a median follow-up of 4.9 years. The analysis by Prakash Deedwania and colleagues (University of California, San Francisco, USA) involved 5584 patients with metabolic syndrome and clinically evident coronary heart disease aged 35--75 years.
The patients were randomly assigned to receive either atorvastatin 10mg per day or 80mg per day (aggressive treatment). At 3 months patients on 10mg per day had mean LDL cholesterol concentrations of 2.5mmol/L, compared with 1.9mmol/L in the aggressively treated patients. Major cardiovascular events occurred in 13% patients receiving atorvastatin 10mg, compared with 9.5% receiving 80mg. Irrespective of treatment, significantly more patients with metabolic syndrome (11.3%) had a major cardiovascular event than those without metabolic syndrome (8%). This increased risk was significantly reduced by intensive therapy with atorvastatin 80mg beyond that achieved with 10mg. The analysis suggests that the risk of major cardiovascular events increases with the presence of each component of the metabolic syndrome, and patients with diabetes also have a much higher risk.
By focusing aggressive statins therapy (80mg a day instead of 10mg a day) on patients with metabolic syndrome or diabetes in a population with stable coronary heart disease, allows the number needed to treat to be reduced significantly, which gains a significant improvement in the cost-effectiveness of high statin dose.
Notes to Editors: Metabolic Syndrome--Although there is some disagreement about the criteria for metabolic syndrome, it is generally described as the clustering of at least three cardiovascular risk factors, such as insulin resistance, obesity, large waist circumference, hypertension, and dyslipidiaemia*. The metabolic syndrome has been closely linked to diabetes and cardiovascular disease.
*Dislipidaemia--A disorder of lipoprotein metabolism, including lipoprotein overproduction or deficiency. Dyslipidaemia may be manifested by elevation of the total cholesterol, LDL cholesterol and the triglyceride concentrations, and a decrease in the "good" high-density lipoprotein (HDL) cholesterol concentration in the blood.
Professor Prakash C Deedwania, Professor of Medicine, University of California, San Francisco, VA Central California Healthcare System, 2615 E Clinton Avenue, Fresno CA 93703, USA. T) +93-4414177 (Hotel Milleni Apsis, Barcelona. From September 2 to 7) [email protected]
Last reviewed: By John M. Grohol, Psy.D. on 30 Apr 2016
Published on PsychCentral.com. All rights reserved.


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{mosimage}Mr. Craig threatens to kill more hostages while instituting a sick system of "demerits." Sonny realizes that all hell will break lose if Mr. Craig doesn't get the briefcase. Mr. Craig handcuffs Sonny and Carly together in the office.
Meanwhile, Jason instructs Sam to make a break for it the first chance she gets so that she can tell the cops what's going on inside. Ric plans on storming the building the minute the vault opens. Unbeknownst to Ric, however, Jason orders Spinelli to implement his computer program which will open the vault ahead of schedule. Ric warns Skye that the threat is real and advises her to flee with Lila while she has the chance.
At the same time, Seven taunts Mateo with unsettling results. Over at the General Hospital, Edward tells an unconscious Alan that he is proud of him. Tracy's words belie the love she feels for Alan. Monica holds herself responsible for Alan's dire condition.
In the meantime, Maxie continues to bond with Three. In a classic case of the Stockholm Syndrome where the hostage begins to befriend the hostage-taker, Maxie doesn't believe that Three would hurt her.
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The England international goalkeeper has overcome a broken foot but accepts that it will be difficult to shift Wales No.1 Boaz Myhill from his place in the first team
The 30-year-old has handed caretaker head coach Keith Downing a timely boost in the wake of Steve Clarke's removal as manager by declaring himself ready to resume first-team duties if needed against Hull City on Saturday.
|West Brom are 2/1 with William Hill to beat Hull City to nil
"It has been a long slow recovery but I'm really, really happy to be back," Foster told the club's official website. "That's me fully fit now.
"We'll have to wait and see what happens on Saturday. Boaz and Luke [Daniels] have both done very well.
"Bo has been great. I know exactly what Bo can produce and his performances haven't surprised me. He's an international goalkeeper and he's been absolutely brilliant."