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- Gene From Father May Raise Celiac Disease Risk in Daughters
Gene From Father May Raise Celiac Disease Risk in Daughters
- By Jefferson Adams
- Published 04/9/2008
- Celiac Disease & Gluten Intolerance Research
- Rating:
Celiac.com 04/09/2008 - Do your chances of developing celiac disease vary depending on which parent is passing on the genes? A new study says yes.
According to the results of a recent study, depending on whether the gene is inherited from the father or the mother, and depending on the gender of the child, data suggest that there could be some variance in rates at which the gene is inherited, along with some variance in the rates of celiac disease.
An Italian research team set out to examine risk differences for developing celiac disease between males and females. The research team was made up of Francesca Megiorni, B.Sc., Barbara Mora, B.Sc., Margherita Bonamico, M.D., Maria Barbato, M.D., Monica Montuori, M.D., Franca Viola, M.D., Simonetta Trabace, B.Sc., and Maria C. Mazzilli, B.Sc.
HLA typing in celiac disease is mainly considered for its negative predictive value, as people who do not carry the DQ predisposing molecules are unlikely to develop the disease. Celiac disease occurs twice as often in women as it does in men. In order to learn more about why this might be, the team of researchers recently performed genotyping for HLA-DRB1, DQA1, and DQB1 loci on 281 female and 156 male pediatric celiac patients, 292 nuclear families, and 551 controls. The team then evaluated and compared the odds ratio, parental origin of the disease-associated haplotypes, and transmission ratio distortion between male and female patients.
Female patients more frequently exhibited DQ2/DQ8 compared to male patients (94% F, 85% M; P = 1.6 Å~ 10−3). The HLA typing test carried a calculated negative predictive value of 99.1% for females and 90.5% for men. Interestingly, the bulk of the 39 DQ2/DQ8 negative cases were male. Looking at the origins of the DQ2 haplotype, the research team noted that 61% of female patients and 42% of male patients carried a paternal combination (P = 0.02).
Looking at the results of the transmission disequilibrium test (TDT) the team noted a major distortion in the DR3-DQ2 transmission from fathers to daughters. Among those patients that are DQ2/DQ8 positive, females showed a higher prevalence of celiac disease than did male patients, with a ratio of 1.8 to 1. Of those patients that were DQ2/DQ8 negative there was a slight tip toward the males, with a ratio of .7 to 1.
The high prevalence of celiac disease in DQ2/DQ8 positive females only applied to females that had inherited the DQ2 haplotype from the father. The results of the study indicate that the sex of the parent supplying the HLA genes may play a role in susceptibility to celiac disease, along with a different effect of parent-specific epigenetic modifications in the two genders.
In all, male patients developed celiac disease more frequently than female patients in absence of HLA predisposing dimmers, but this was due to the occurrence of two DQB1 susceptible alleles that seem to increase the disease risk for males. The results lead the research team to believe that the presence of DQ2 and/or DQ8 molecules is a stronger risk factor in females than in males (ORF = 40.5, ORM = 14.1). Additionally, the results also indicate that HLA typing, which is mainly considered for its negative predictive value in celiac disease, is of greater importance in the testing of females than in males, with calculated negative predictive value of 99.1% and 90.5%, respectively, which points to the need to factor gender into the calculation of disease risk.
These findings, taken together with the revelation that inheritance of a paternal DQ2 haplotype led to celiac predominance in daughters, show that HLA genes play a role in the disease sex bias, and imply a potentially different effect of parent-specific epigenetic modifications in the two genders.
Am J Gastroenterol 2007; 102:1–7
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Jefferson Adams
Jefferson Adams is a freelance writer living in San Francisco. His poems, essays and photographs have appeared in Antioch Review, Blue Mesa Review, CALIBAN, Hayden's Ferry Review, Huffington Post, the Mississippi Review, and Slate among others.
He is a member of both the National Writers Union, the International Federation of Journalists, and covers San Francisco Health News for Examiner.com.View all articles by Jefferson Adams
10 Responses:
Amy BaldwinRating: ( Author)
said this on
10 Apr 2008 6:23:15 AM PDT
I have suspected that I inherited from my father, this makes sense. My parents have both died as well as my only sister. My brothers are fine and do not have celiac.
(Comment Replies Disabled)
marcia terronesRating: ( Author)
said this on
10 Apr 2008 6:43:02 AM PDT
Very interesting! I am having the Celiac gene testing done right now so this is very newsworthy to me. I'll have to get my father tested if mine comes back positive for DQ2/DQ8.
(Comment Replies Disabled)
Carol the DabblerRating: ( Author)
said this on
10 Apr 2008 1:20:52 PM PDT
After reading this article all the way through, I scarcely know any more than I did after the headline caught my eye. I have one copy of the DQ8 gene, which I suspect came from my late father (who had many celiac-type symptoms), and would very much like to read a 'translation' of this article written for non-geneticists.
(Comment Replies Disabled)
JaymeaRating: ( Author)
said this on
11 Apr 2008 3:34:27 PM PDT
Me too,I had positive results for DQ2/and or DQ8, and I'm a female - I guess that's revealed by the results if mostly females have those results. I think it came from my paternal line, but not from my dad, but the dad before (granddad). The article is a very good study!
(Comment Replies Disabled)
Lue CrossRating: ( Author)
said this on
11 Apr 2008 6:44:42 PM PDT
I found this article very interesting. I have thought for a long time that my celiac (dx 1997) came from my father. For years before his death in 1976 he complained of stomach problems. He ate large amounts of bread, gravy etc.
(Comment Replies Disabled)
Robert ReevesRating: ( Author)
said this on
12 Apr 2008 3:01:11 PM PDT
As a confirmed celiac for 1 year my youngest daughter has the same symptoms that I had as a child, she is 14 and looks 9 years old. I have already put her on a gluten free diet and I'm waiting now to see if it helps. PS It took 6 months of doctors and tests before they tested me for celiac disease.
(Comment Replies Disabled)
Kathy JoyRating: ( Author)
said this on
12 Apr 2008 7:02:19 PM PDT
I know I have it I was tested my father just died and he had it for many years at least 30 and there were six kids in my family and I lost a sister she may have had his blood type and maybe even had it with different symptoms. She was vomiting all the time. I know I have his blood type and genes. My brother has his blood but has not shown a sign of it yet. I hope he doesn't. I have a son and thank GOD I do not want him to have it. It seems stress brings it on. I have had it for 12 years now.
(Comment Replies Disabled)
Ruth WalderRating: ( Author)
said this on
13 Apr 2008 11:16:57 AM PDT
2 of 3 sisters are biopsy diagnosed. We have suspected that my deceased father had many symptoms as did his mother. Now, I am concerned about my nephews young daughters having the genetic predisposition for Celiac Disease.
(Comment Replies Disabled)
AstraRating: ( Author)
said this on
13 Apr 2008 4:32:49 PM PDT
It is a great article. I am gluten sensitive, so is my father, so was his mother's sister (his mother died young) but I do not have DQ2 OR DQ8. Hope more reliable testing will be developed soon.
(Comment Replies Disabled)
TerriRating: ( Author)
said this on
21 Apr 2008 6:07:09 PM PDT
Great article. My father, deceased at age 40, exhibited at least two of my celiac symptoms, stomach pain and anemia. I am certain that I am celiac because of him, I have two first cousins on my fathers side with it as well...I have not had genetic testing done, but probably should. My daughters tested negative, but what of my grandson's future children?
(Comment Replies Disabled)
In Celiac.com's Forum Now:
This article, and the comments below, may be helpful: https://www.celiac.com/articles/21721/1/How-Celiacs-can-Deal-with-Accidental-Gluten-Ingestion/Page1.html
Long ignored and dismissed as unscientific and crude, are intestinal worms destined to be the future of autoimmune disease treatments? Hookworms. Intestinal parasites. They sound gross. The thought of having one's gut infected with a parasitic worm generally makes people's skin crawl. Indeed, in...
well, we're in sort of similar positions but can l ask what made you go gluten-free 3 years ago? You've kept the diet for quite some time so where the health problems serious? at the time was seeking testing not an option? For myself, l absolutely tried everything to gain weight ...
I can not add anything else, but I hope you feel better fast!
Welcome! I am so sorry that you are dealing with this. With all your testing was active celiac disease ruled out? Did they check for UC or Crohn's? Flies? I am on the West Coast. The wind is usually too steady for any insect to hang around at the beach, but I recall getting attacked by...


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On Thu, May 29, 2008 at 04:44:19PM -0400, Tom Lane wrote: > David Fetter <david(at)fetter(dot)org> writes: > > On Thu, May 29, 2008 at 09:54:03PM +0200, Peter Eisentraut wrote: > >> I think the consensus in the core team was that having > >> synchronous log shipping in 8.4 would already be a worthwhile > >> feature by itself. I'm sorry if I was unclear on this. I don't disagree that it would be a worthy feature. I do disagree with the idea, given this goal, that we can expect to ship 8.4 without a built-in replication and have that be good enough by itself. > > If that was in fact the consensus of the core team, and what I've > > been seeing from several core members in this thread makes that > > idea unclear, it's out of step with the stated goal of the > > feature. Having some kind of half-way, > > doesn't-actually-quite-work-out-of-the-box "replication" will make > > things worse and not better. > > What is your justification for denigrating this plan with that? Or > are you merely complaining because we know we won't be all the way > there in 8.4? Again, just my humble opinion, but given the stated goal, which I agree with, I'd say it's worth holding up 8.4 until some kind of out-of-the-box replication advances that goal, where Yet Another Toolkit Suitable For People Who Are Already Database Kernel Hackers To Build Replication Systems On Top Of does not. Cheers, David. -- David Fetter <david(at)fetter(dot)org> http://fetter.org/ Phone: +1 415 235 3778 AIM: dfetter666 Yahoo!: dfetter Skype: davidfetter XMPP: david(dot)fetter(at)gmail(dot)com Remember to vote! Consider donating to Postgres: http://www.postgresql.org/about/donate
Next: From: Bruce Momjian Date: 2008-05-29 20:54:04 Subject: Re: Core team statement on replication in PostgreSQL Previous: From: Shane Ambler Date: 2008-05-29 20:50:27 Subject: Re: Initial max_connections for initdb on FreeBSD.
Next: From: Bruce Momjian Date: 2008-05-29 20:54:04 Subject: Re: Core team statement on replication in PostgreSQL Previous: From: Tom Lane Date: 2008-05-29 20:44:19 Subject: Re: Core team statement on replication in PostgreSQL

subset: commoncrawl


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Q&A of the Day: How much does Latisse cost?
Will-Lee on 30 Jun 2009 at 11:57am
In today's Q&A of the day, RealSelf user Miss Yates is looking for the answer to a question a lot of our community has been asking:
What's it going to cost me to get longer lashes with Latisse?
As Miss Yates found out, over 30 of our MDs chimed in, and the general consensus is that it's about $120 for a 60-day supply (at least that's what Allergan is suggesting).
Dr. Eric Joseph in West Orange, NJ says he's using a slightly different treatment regimen, so a $120 bottle will last you four months. And SF plastic surgeon Corey Maas, MD is offering it at cost -- $92 for a bottle. And the range (for various amounts) can veer between $72 and $150.
Wherever you get it, watch out for possible side effect that have been reported, as Dr. Arnold Oppenheim points out, including patients "having their blue eyes turn brown."


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Sen. Chuck Grassley (R-IA), the top Republican on the Senate Judiciary Committee, said during a hearing on Wednesday that a bill seeking to revive provisions of the Voting Rights Act that were recently struck by the Supreme Court has "problems" because it may prevent states from enacting a common form of voter suppression law. The proposed fix to the Court's decision, according to Grassley, "seems to create only a fig leaf of protection for legitimate voter ID laws," and it "arguably . . . contains a backdoor mechanism that will be used to negate legitimate voter ID laws."
There is no such thing as a legitimate voter ID law. Although proponents of these laws often defend them because by claiming that they are necessary to combat voter fraud at the polls, in-person voter fraud is virtually non-existent. What voter ID laws do accomplish, however, is that they prevent many low-income, student and minority voters from casting a ballot, all of which are demographic that tend to prefer Democrats to Republicans.
Grassley previously suggested that he will hold the Voting Rights Act fix hostage unless it contains a carve out protecting voter ID laws — he said at a hearing last July that any bill responding to the Supreme Court's decision "should not threaten common-sense measures to ensure the integrity of voting, such as constitutional voter identification laws." The proposed legislation, however, does contain a carve out for voter ID laws — it provides that these laws may not count towards the new formula that will be used to determine which states must "preclear" their voting laws with federal officials before those laws take effect. Grassley's comments on Wednesday, however, suggest that this compromise provision is not enough to earn his support for the bill.
Other statements by Republican senators yesterday should trouble voting rights supporters hoping for bipartisan support for the bill. Sen. John Cornyn (R-TX) said the fix is "clearly unconstitutional under the Supreme Court's precedents." Sen. Mike Lee (R-UT) said there will be a "risk of manipulation" if the Justice Department regains its ability to screen voter suppression laws. Sen. Ted Cruz (R-TX) accused the Justice Department of using the Voting Rights Act to protect "the ability to elect Democrats." And Sen. Jeff Sessions (R-AL) said that "to pass a law in the U.S. Congress that provides penalties only to some states and not to others can only be justified for the most extraordinary circumstances. And the justification no longer exists."


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Match by match, Trinity High School's wrestling team is finding out the Mark Powell way of competing is working.
Powell, the first-year head coach, has worked to get the wrestlers to buy into his system. It involves a lot of hard work, listening to Powell's directives and demanding a persistent push to improve.
All of it was on display Wednesday evening in the Hillers' gymnasium in a brick-by-brick teardown of Chartiers Valley, 48-28, in a Section 4B dual meet.
The win moved the Hillers to 3-0 in the section, 9-8 overall, and sets up a showdown next Wednesday at Waynesburg (2-1) for second place. Canon-McMillan (4-0), the No. 1-ranked team in the O-R Wrestling Ratings and the No. 5 team in the state by Intermat, waits in the regular season finale Jan. 16.
A second-place finish would set the Hillers up with the Section 4B leader – heading into last night's matches, it was Hopewell – for a decent seed in the WPIAL Class AAA Team Tournament.
"The guys are listening and putting in the work," Powell said. "They keep plugging away and improving on the little things, and it's nice to see that."
Trinity bolted to a 24-0 lead after the match began at 195. Don McWreath and Connor Fritz (220) made it 12-0 with pins and CV (0-4) forfeited to heavyweight Evan Seaman for an 18-0 bulge. Tristan Buxton capped the run with a pin of Justin Sullivan at 106.
"For us, mat time is the most important thing," he said. "We want to get them quality time and build their confidence. All of our guys are healthy and definitely in shape."
Mat time was hard to come by for some Hillers, but for a good reason. Buxton's pin was in 1:19, and Fritz's was in 1:10. Justin Ritter had one in 1:10 at 138 pounds; Evan Sherrieb stuck Gus Goedel in 1:05 at 152 pounds, and Robert West capped the dual meet with a pin of Dom Politi in 1:19 at 182. Ryan Yocum spent the most time on the mat during Trinity's seven pins, lasting 3:39 before disposing of Alex Preuax.
"We're young and inexperienced," said Chartiers Valley coach Bill Evans. "We're building for the future, and Trinity looked pretty good out there."
West, in particular, is having a strong season. Only a sophomore, West won all seven bouts in the North Coast Classic, and his pin of Politi was as physical as it was quick.
"He's not making mistakes, and that's important," said Powell. "He missed his eighth-grade season because of a broken arm. He's getting mat time. He looked poised out there, and he doesn't get rattled. Anytime you have good technique and skills, the moves will work for you. Right now, there are no little mistakes. Every move he makes, he's scoring on."
Powell also was impressed with Yocum, who is only a freshman.
"He's going to be a good one," said Powell. "That's what we expected. He's come a long way. Everyone is having faith, and they are having success. I preach for them to have faith, and they are starting to believe."
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How to pay off your campaign debt
A puzzled colleague forwards over an email to Hillary Clinton's list, on behalf of the campaign for the National Popular Vote, an attempt to defang the electoral college through state pledges to back the popular winner in presidential elections.
"You are receiving this message as a member of HillaryClinton.com's online community. Please take a moment to read this special message from the Kentucky Campaign for a National Popular Vote. The Kentucky Campaign for a National Popular Vote is solely responsible for the content of this message," says the version of the email I was sent, before diving into the arguments for the plan.
Now, Clinton has been renting out her email list since her defeat to retire her campaign's remaining debt, so there's nothing particularly unusual about a stray bit of advocacy to the list.
One note, however: The NPV campaign recently signed up Buffalo billionaire Tom Golisano, a generous contributor to, among other things, the Clinton Global Initiative. He's obviously a genuine supporter of the plan -- but by underwriting the rental of Clinton's list, he's also throwing some money in the direction of an old friend.
Full email after the jump.
---------- Forwarded message ----------
From: National Popular Vote
Date: Wed, Mar 16, 2011 at 8:05 AM
Subject: Your action now can fix Electoral College
You are receiving this message as a member of HillaryClinton.com's online community. Please take a moment to read this special message from the Kentucky Campaign for a National Popular Vote. The Kentucky Campaign for a National Popular Vote is solely responsible for the content of this message.
The Electoral College needs fixing.
Your action NOW can make the difference because the Kentucky Legislature is currently considering the National Popular Vote bill to reform the Electoral College.
Under the National Popular Vote bill, the presidential candidate who gets the most popular votes in all 50 states and DC will become President.
Please take a moment to e-mail your state legislators and urge them to support the National Popular Vote bill.
Because electoral votes are currently awarded to the candidate who gets the most popular votes inside each separate state, candidates don't pay attention to issues of concern to voters in states where they are comfortably ahead or hopelessly behind. In 2008, candidates concentrated two-thirds of their campaign events and money in just six closely divided "battleground" states. They spent 98% of their time, money, and effort in just 15 states. Our state is a mere spectator in presidential elections. On the other hand, votes in our state would matter if the President were elected by a national popular vote because every vote would be equal.
The states have the constitutional authority to change the method of awarding electoral votes so as to establish a national popular vote for President. The National Popular Vote bill has already been enacted into law by Hawaii, Illinois, Maryland, Massachusetts, New Jersey, Washington state, and the District of Columbia. The bill has also been approved by at least one legislative house in 15 other states, and it recently passed the New York Senate 52-7. The bill has been endorsed by 2,011 state legislators around the country.
If you believe that a vote cast in our state should count as much as a vote cast anywhere else, and that the candidate who gets the most popular votes should win the White House, please take a moment to e-mail your state legislators and urge them to support the National Popular Vote bill.
The National Popular Vote bill is endorsed by Common Cause, FairVote, the League of Women Voters, Sierra Club, NAACP, National Black Caucus of State Legislators, ACLU, the National Latino Congreso, Asian American Action Fund, DEMOS, National Coalition on Black Civic Participation, Public Citizen, U.S. PIRG, the Brennan Center for Justice, and Defenders of Wildlife Action Fund.
The bill has been endorsed by newspapers such as The New York Times, Boston Globe, Chicago Sun-Times, Minneapolis Star-Tribune, Los Angeles Times, Miami Herald, Hartford Courant, Sacramento Bee, and many more.
As the Sarasota Florida Herald Tribune said: "The most compelling and practical alternative is promoted by a bipartisan group called National Popular Vote. The NPV proposal calls for legislatures to pass bills committing their state's electoral votes to the candidate who receives the most popular votes nationwide; the bill would take effect only when enacted by states that together have enough electoral votes to elect a president."
Learn more at www.NationalPopularVote.com.
Thank you.
Campaign for a National Popular Vote
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SAN DIEGO, CA--(Marketwired - October 09, 2013) -
Interferons (IFNs) are highly potent biotherapeutics that mimic naturally occurring human proteins released by a patient's own host cells in response to a number of disease processes. They allow for communication between cells to trigger the protective defenses of the immune system. IFN beta-1a and IFN beta-1b are used to treat and control multiple sclerosis, slowing disease progression and reducing flare ups.
While Aegis now has more than a dozen issued formulation patents related to peptide, protein, and small molecule therapeutics, this patent marks the first issued patent relating to non-invasive direct delivery of protein drugs to the central nervous system. Elimination of repeated injections for chronic diseases provides significant convenience for patients and direct delivery to the CNS will allow proportionally smaller doses and reduction of unwanted systemic drug exposure, together potentially reducing unwanted side effects.
To receive future press releases directly via email click on http://www.aegisthera.com and enter your email address in the sign-up box at the bottom of the page.
About Aegis Therapeutics
Aegis Therapeutics LLC commercializes its patented drug formulation technologies through product-specific licenses. Intravail® drug delivery technology enables non-invasive delivery of a broad range of protein, peptide and non-peptide drugs that can currently only be administered by injection, via the oral, buccal, and intranasal administration routes, and with high bioavailability. Our ProTek® excipients stabilize, prevent aggregation, and reduce unwanted immunogenicity of protein and peptide therapeutics while avoiding oxidative damage caused by polysorbate surfactants.
For more information about Aegis, please visit: http://www.aegisthera.com.


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Highlights from the 2009 Point-in-Time Count of People Who Are Homeless
On Jan. 28, 2009, there were 1,730 people who were literally homeless in the Fairfax-Falls Church Community.
663 of them were single individuals and 1,067 were people in families.
- The 2009 Point-in-Time count shows that the overall number of homeless persons decreased slightly in the past year, by 5.7 percent from 1,835 to 1,730.
- Nearly 62 percent of all homeless persons were in families, and 36 percent were under age 18.
- The number of single individuals counted decreased by 81, and the number who were unsheltered decreased from 212 in 2008 to 129 in 2009.
- The number of persons in families remained constant, but with more adults and fewer children under age 18.
The annual Point-in-Time Count of Homeless Persons in the Fairfax-Falls Church Community follows the U.S. Department of Housing and Urban Development (HUD) reporting guidelines and covers people who are literally homeless – those who are in shelters, in transitional housing or unsheltered living on the street.
- The count does not include people who live in temporary arrangements but do not face immediate loss of shelter, or self-pay to live in a motel.
- The homeless number also does not include formerly homeless persons who live in permanent supportive housing.
However, an additional 26 permanent supportive housing beds for single
individuals were added since the 2008 Point-in-Time Count and this may
be one factor contributing to a lower number of homeless
2009 Highlights from Point-in-Time Count (PDF)
For more information on the 10-Year Plan to Prevent and End Homelessness, visit www.fairfaxcounty.gov/homeless.


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Inferring Evoked and Consideration Set from Scanner Data
Evoked and consideration set have been one of main research topics in marketing field for a long time. Using interview data, many studies have been conducted to investigate the nature of its content. However, only few studies tried to do so by using consumer purchase history. By modeling the process of evoked and consideration set formation, in this research we try to elicit consumer evoked set from scanner data. Some managerial implications for marketing decisions derived from the information of estimated evoked set are discussed.
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|Dec 2011
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| Web page: http://www2.econ.osaka-u.ac.jp/library/global/e_HP/e_g_shiryo.html
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Over the past couple of months, Vin Diesel has seemingly been on a one-man marketing mission for the upcoming sci-fi actioner Riddick, releasing weekly images of himself as the anti-hero Richard B. Riddick in writer-director David Twohy's sequel to Pitch Black and The Chronicles of Riddick. Well, Diesel has now stepped it up a gear by giving us the official first-look teaser trailer via his official Facebook page, and you can check it out below.
"The infamous Riddick has been left for dead on a sun-scorched planet that appears to be lifeless. Soon, however, he finds himself fighting for survival against alien predators more lethal than any human he's encountered. The only way off is for Riddick to activate an emergency beacon and alert mercenaries who rapidly descend to the planet in search of their bounty. The first ship to arrive carries a new breed of merc, more lethal and violent, while the second is captained by a man whose pursuit of Riddick is more personal. With time running out and a storm on the horizon that no one could survive, his hunters won't leave the planet without Riddick's head as their trophy."
Riddick is set for release in North America on September 6th, with a cast that also includes Karl Urban (Star Trek Into Darkness), Katee Sackhoff (Battlestar Galactica), Jordi Molla (Colombiana), Bokeem Woodbine (Total Recall), Dave Bautista (The Man with the Iron Fists) and Nolan Gerard Funk (Glee).


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From our colleague Ishaan Tharoor at World Views:
It's been a bad week for women in media on both sides of the pond. On the same day we learned of Jill Abramson's forced departure from the New York Times, the leading French daily, Le Monde, announced the resignation of its own female editor-in-chief, Natalie Nougayrède, who had been in charge for just a year.
Following her resignation, Nougayrède issued a personal letter, published on Le Monde's Web site. "I cannot accept being undermined as head of the paper," she wrote. "I no longer have the means to run it with all the necessary peace and serenity that is required."


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Part 1 of 1, one fight, total duration (min:sec): 27:53
Price: 6 Credits
Buy or rent this title for your website.
,Size: 157.34 MB
This is an exciting sex wrestling match from the late 90tees. Those of you who like competitive nude matches only will enjoy their intense wrestling in the first 10 minutes. However, the girls start sweating and are getting exhausted since theyre so evenly matched. Step by step their wrestling gets slower while they are trying to overpower each other sexually. Who could resist Melanie? Joanna certainly cant. But shes a mature and experienced woman who surprises Melanie with much more lesbian tactics than just any variations of tribadism. She does literally everything to keep herself in the game, otherwise there would have been a clear winner since Joanna enjoys Melanies fit and sensuous body. But as she uses her best lesbian tactics it is Melanie who shows a weakness. Can she turn around? Wholl be the winner? If you like real sex wrestling then thats a must see.
Attention! The description for the videos is a valid overview for the FULL video. However, some scenes or parts of a video could sometimes vary.
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Average Customer Review: (4.6 stars)
Battle of the Best
(Tuesday, July 18, 2006)
Reviewer: Beginner
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I really resisted giving this 5 stars. While the video is quite good I was hoping for more missionary trib. Whenever I see Joanna listed as one of the players, I know that missionary trib will definitely be present. You can also be guarenteed the scissor trib with Melanie as it is her favorite position as evidenced by her videos. I have watch both in many videos and they are to me in my HO the best of the best. They both like women and both like what they do and what they bring to the match. Both are excellant and this video is close to that. The action is well done and then the sensual erotic moves that begin are also very well done. I would love to see Melanie be more sensual as she was here. A rematch with love making would be dynamite without doubt. With coin of the realm being tight right now, it is important to make very good decision on what I buy. This was worth the money.
An oldie but goodie!
(Wednesday, August 02, 2006)
Reviewer: john
- See all my reviews
Of all the films here, the Oscar has to go to this one.
It must be an oldie from some time back because both of these ladies have retired now (pity), as far as I know. It starts out with some spirited nude wrestling, but it's not long before the two ladies lock up p-to-p. The look on Melanie's face as she grinds away tells you that this is the real deal. She's really into this stuff and it shows. If you've seen her in similar action with Wanda in HPC24, you'll know what I mean.
And there's much more than just trib here.
DWW should dig these two out of retirement with a good offer, and let them do a rematch. This one's about as HOT as it gets. The only nitpick I can come up with is that the wrestling segment at the start was slightly too long. Put this one at the top of your download list. Simply outstanding (or should that be upstanding!)
(Sunday, September 10, 2006)
Reviewer: perikles
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beide frauen bringen sehr viel action ins spiel, was aber manchmal etwas uebermotiviert aussieht... es gibt einige ansehnliche szenen, in denen sich die beiden maedels "zur hand" gehen - hier haette ich mir eine etwas kreativere kamerafuehrung gewuenscht... manchmal wirken beide leider etwas oberflaechlich in dem versuch, die partnerin zu befriedigen oder zu ueberwaeltigen... schade, denn in beiden steckt einiges und ich finde sie zwei sehr interessante charaktere.
Excellent old stuff
(Friday, September 29, 2006)
Reviewer: ole
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Great idea to show again this beautiful match between lesbian-veteran Joanna and the sex-queen Melanie. The fight is not only serious, it is also extremely erotic, with a remarkable 69- action (although we do not see much of Melanie's action). The only missing aspect is kissing: but I guess J/M did not really liked each other very well.
Oh boy...nostalgia making me teary
(Sunday, December 24, 2006)
Reviewer: Dr. Tribology
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Ha! Nah, I'm not that big of a sap. But this clip sure does remind of the hall-of-famers of old. Wouldn't you love to see Melanie (or your favorite veteran) get into the mix with the lovely new crew of models? I would imagine Melanie leaving most of them tied in pretzels and wet from exhaustion and defeat. Ah, what would it take to make that a reality JR?!
Anyhow, the previous reviews are a good summation of what to expect. I should highlight the fact that there is some 69 in this clip, a rarity around here. The girls are as fit as I remember them and they love to grind! My favorite scene is near the end where they get into a reverse open scissors position (where one is face-down and the other is face up). You can tell that they are both hitting the "sweet spot".
Highly recommended
Tribadism *****
Wrestling ****
Competitiveness ****
Beauty ***
Erotic ****
Overall *****
A HPC Legend
(Sunday, September 16, 2007)
Reviewer: Tribby
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Like the title says, this was a HPC Legend in my opinion to be added to the classic library. Of course there are few other rounds that have ranked equally (the classics) to the top along with this match between Joanna and Melanie.
The similar erotic match that are equaled with this (TRIB-0048) would be Wanda vs Melanie, both matches were really erotic for my taste but I must say that I'd "preferred" the transition of wrestling-to-sex from Wanda and Melanie better than Joanna and Melanie since it showed the horny-spark of Wanda wanting to mount her pussies on to Melanie after that erotic hold from the approx. 8 minutes and 41 seconds of wrestling action. In TRIB-0048, the transition of wrestling-to-sex were non-existent because of that instant video change to the erotic stuff.
Enough about the technical stuff above so let's get straight to the point: overall this was highly erotic, greatly performed! This should be another straight on inspiration for newer Tribgirl productions whenever it involves rugged catfight that blends with erotic wrestling.
It started out with some intensed wrestling, funny how I felt that Melanie was too much work for Joanna to handle since she has been the dominated one in most of the HPC series. Melanie was great from start-to-finish.
Melanie, the real erotic/sweaty queen: I just loved her face expressions (it's still hot even if she was acting or real) during the whole bout. Plus the tied up hair of hers looked so hot when it became too loosened from the flip and flops with Joanna. Although it felt that there was a signal for her to remove her hair-band from the audience but none-of-the-less: she looked real erotic when she removed her hair-band anyways.
There were the erotic moments of finger rubbing pussies, the nice re-pose of Joanna licking Melanie's butt (not pussy) was an excellent instant capture, Joanna's mouth were fully mounted on to the Melanie's hotspot (which I would like to see more often instead of soft licks), the sweat was also good but not as great as the round with Wanda vs Melanie.
I must comment on all those creative (never-seen-before) erotic positions should greatly be used more often in the newer Tribgirls because the moves in TRIB-0048 was an incredible genuine mood to watch. Probably the best.
After seeing those great positions; I really do wish the newer Tribgirls would try these concepts (not just for the fans but for themselves to enjoy). Even though I've seen some nice ones lately from the newer offerings but further positions should continuously be explored of all the possibilities to mount their hot spots in.
Most of the fans and producers here may already know that my high ratings of each video has always been due by many factors of rugged-raw erotic wrestling. TRIB-0048 is one excellent example of good rugged-raw action (from the HPC catalog) along with other great numerous newer TRIBGirl rounds that I've seen which was the main reason that I've rated more than the stars given.
I personally would say that TRIB-0048 is the foundation concrete of what TRIBGirls are today and the producers at DWW are doing a great job providing selected great rounds (that contains intense catfight with a hot dose of "Tribadized"-sex). The sensual slow stuff no need to apply.
Great work from the past.
Melanie VS
(Saturday, September 22, 2007)
Reviewer: mohamed
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i wonder when melanie will come back for some newer videos, bring her back tribgirls.com
melanie for me is one of the best at this.
i love her actions and facial expressions when she lets herself go.
if you have any more hpc or tribgirl videos of melanie you should put these up here as it will always be a welcome addition.
Power and Finesse
(Monday, July 14, 2008)
Reviewer: Michael
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I truely love the early HPC wrestling sexfights. They had everything wrestling and sexfighting. This match is one real gem.
You have two ladies who seem to love wrestling another woman nude. You have Joanna who is all about straight ahead power to dominate her opponent and then you have Melanie who is all about finnese toget the right angle on her opponent.
This match starts off with great commpetative wrestling and then slowly turns into aggresive sexfighting and finally into a full blown sex match. I like the fact that they didn't just jump to having sex right away they actualy wrestled for some time then slowly progressed into the trib part of their match. It looked like a very natural progression.
The video work is quite good on this match. On more than one occasion I have been watching a sexfight hoping to see a better angle of the two combatents bodies intertwined. Whom ever did the camera work on this one managed to catch the women at all their best angles.
Like one of the other reviewers of this video I too have to agree that it is a rare treat to see some 69 action from the wrestlers in a sex match and this one had some great moments of it.
If you are likemyself and like to see the ladies really wrestle before settling down to a sexfight then this is a good one to own.
Melanie is beautiful.
(Thursday, August 14, 2008)
Reviewer: Wilf
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This is from how long ago? Wow, these two know how to compete! The match starts with fast-paced, equal wrestling. The way these two fight makes it difficult to believe that only a few minutes later they will be sex fighting. Of course, that also sets these two apart: they are true competitors no matter what the competition. One thing I noticed about this match was the butt contact. I rarely see butt-to-butt contact in a wrestling match, and it is wonderful to see, especially because its incidental. And few are as shapely as Melanies. The camera does a good job of providing us these views instead of moving to the side, as is done time and again these days.
My one complaint about the wrestling is that one wrestler stalls whenever she is not in control, which means there are large swaths of time when nothing of substance happens. The wrestling lasts for less than half of the video before things take a turn.
Melanie is great to watch and listen to. First, she is a tremendous performer. Second, she has no qualms about holding back her emotions, physically or vocally.
And Joanna certainly knows how to work a womans body. This match from the old days easily could fit in with todays because it is passionate, uninhibited, and unpredictable. Its not always the case, but in watching this video you truly get a sense that these two are competing and not just in it for personal pleasure.
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text: On Fri, Jan 6, 2012 at 14:41, Travis Oliphant <email@example.com> wrote: > > > -- > Travis Oliphant > (on a mobile) > 512-826-7480 > > > On Jan 6, 2012, at 12:34 AM, Nathaniel Smith <firstname.lastname@example.com> wrote: > >> On Thu, Jan 5, 2012 at 9:15 PM, Travis Oliphant <firstname.lastname@example.com> wrote: >>> What is an isn't Pythonic seems to be a matter of some debate. I *really* like the idea of unifying those arguments. That simplifies the interface considerably. >> >> Yes, I try not to throw around "Pythonic" as an argument, since it >> tends to turn into a slur rather than an argument. But this just >> strikes me as so fundamentally at odds with Python's conventions that >> I'm not sure what else to say. >> >>> I can understand the argument that it would be better to be explicit about it however. I see a couple of options: >>> >>> 1) add a property to the function to indicate what kind of function it is --- a simple 'kind' attribute on the function >>> 2) wrap up the function as the callable of a Singleton Class --- one kind for each "type" of function call. >> >> I'm honestly baffled at how any of this would simplify the interface >> at all. We have two types of callbacks that might optionally be >> passed, and they have totally different calling semantics. The >> simplest way to represent that is to have two optional arguments. If >> we shove them both into one argument but still have two types of >> callbacks and then add some extra (possibly unreliable) machinery to >> disambiguate them, then isn't that more complicated, not less? >> >> The original API: >> behavior 1: optimize(f, hess=f_hess) >> behavior 2: optimize(f, hessp=f_hessp) >> The getargspec API: >> behavior 1: optimize(f, hess=f_hess) >> behavior 2: optimize(f, hess=f_hessp) # don't worry, we'll always guess right! >> The property API: >> behavior 1 : optimize(f, hess=f_hess) >> behavior 2: f_hessp.kind = "hessp"; optimize(f, hess=f_hessp) >> The class API: >> behavior 1: optimize(f, hess=f_hess) >> behavior 2: optimize(f, hess=this_is_really_a_hessp(f_hessp)) >> >> How are the other options simpler than the first? > > This would be done most easily with a decorator when the function is defined, of course. Also, the automatic discovery mechanism will work in most simple cases. The decorator could be used in more complicated situations. You can't add attributes to C- or Cython-implemented functions, by decorator or otherwise, and getargspec doesn't work for them either. > Also it should be emphasized that this change is in the context of optimization unification. Giving the main interface 2 Hessian arguments makes that function more confusing to new users who mostly won't need to deal with Hessians at all. I don't really see why. The original docstring describes both at the same time in the same block of text. I can't imagine any serious additional cognitive overhead if you don't need Hessians. But I don't have access to enough new users to really test this claim. > So, I like this change because it simplifies things mentally for more than 99.9% of the users while all the concerns are about possible complexity or confusion are for less than .1% of the users of the main function. Confusion which can be alleviated with decorators. > > My view is that simple things should be simple --- especially for the occasional user. My main problem with this view is that I don't think that whether you need a Hessian or not is the reasonable line to draw between "simple things" and "not so simple things". The problem with using getargspec() is that it is unreliable. It doesn't work for many reasonable inputs (like say a wrapper function that wraps the real function with one that takes *args,**kwds or extension functions or bound methods or objects with __call__). Knowing that you have one of these cases requires some rather deep experience with Python. I'm sure I've missed a few in my list. So yes, if you have a problem that involves computing the Hessian, you do have a more complicated problem than one which does not involve Hessians, and you should expect to have to implement a somewhat more complicated solution. You should not be expected to know deep details about Python's implementation to understand why your function failed mysteriously. -- Robert Kern "I have come to believe that the whole world is an enigma, a harmless enigma that is made terrible by our own mad attempt to interpret it as though it had an underlying truth." -- Umberto Eco


text:
By Hal M. Bundrick
NEW YORK (MainStreet) December saw the fewest announced job cuts in 13 years, but January seems to be making up for lost ground. Last year, layoffs were down about 3% from 2012, according to global outplacement consultancy Challenger, Gray & Christmas, Inc. But with 2014 barely underway, many high-profile job layoffs have already been announced.
Retail and technology companies seem to be resorting to the most right-sizing.
Intel has already announced that it will trim 5% of its workforce by the end of the year, totaling some 5,380 workers, while setting aside $200 million for restructuring charges. Hewlett-Packard has admitted that it will be cutting 5,000 jobs on top of the 29,000 layoffs announced last year. The company says it's all a part of an ongoing restructuring program to reduce headcount by 10%.
Dell is on the head reduction radar as well. The Register, a British technology publication, is citing "inside sources" as saying the Austin-based computer company will announce the release of 17,000 or more employees next month. The company has denied any such plans.
Meanwhile, IBM has allocated $1 billion for a "workforce rebalancing charge" in the first quarter, according to CFO Martin Schroeter. This is on top of the $1 billion charge the company took last year to implement massive job cuts.
January is a traditional time for retailers to realign their operations, with 44% of annual store closings since 2010 occurring in the first quarter, according to the International Council of Shopping Centers. JC Penney, Macy's and Target have already announced wide-ranging layoffs and store closings.


text: Paulo Lozano holds a case displaying the construction phases of small thruster made of silicon, gold, and porous metals that will be used in orbit on small satellites. Lozano is the Associate Director of the Space Propulsion Lab and an Associate Professor of Aeronautics and Astronautics at MIT in Cambridge, Massachusetts, USA. Lozano's current research focuses on the development of small thrusters for satellites. The thrusters his lab has developed are about the size of a single die cube and contain enough fuel to power the thrusters for a year in space. The thrusters will be used on small satellites.


text:
What do you think happened to Grimlock? I have no clue. Did he die? I couldn't really tell. And if he survived what do you think is the likelyhood of his being a playable character in the next game?
What do you think happened to...(Spoilers)
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He's one tough mother, so probably still alive. Next game who knows, if they are willing to take it as far as Earth it's going to be interesting to see how well they handle the transition.
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I don't think you get rid of such an awesome character like Grimlock. He'll be back. I mean Matt Teiger pushed so hard to get Hasbro to let him have the Dinobots in this game, High Moon can't just let them go so quickly.
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I just finished the game yesterday (It was great fun btw, I wish the entire game was more like the final mission though. That was very the new Mortal Kombat like in it's seamless transitions), but I encountered a bug during the Grimlock stage where Optimus didn't show upon the vid-com when he and Grimlock were talking. Weird. And did I miss it or did Grimlock never devolve enough mentally to actually say "ME GRIMLOCK KING!"?
I know it's 6 months later, but I just am reading these threads now.
They covered Grimlock's fate in the IDW comic book sequel that solely feature the Dinobots I'm pretty sure. The series is called Rage of the Dinobots.
That being said I suspect there won't be a third game since the events of this seem to lead right in Transformers : Prime cartoon show. Theoretically both are in the same continuity (which Hasbro calls the Aligned continuity) but as I previously mentioned there are some really weird inconsistencies between the game series and the cartoon show for something that is supposedly in the same fiction. The Rage of Dinobot comic series contradicts some of the game's events as well....
@slag: It is a shame, but I had the same suspicion upon finishing the game. They managed to make the games that they did because they occupied a less-explored area of the Transformers history. The fan in me would like to see their take on the events that transpire thereafter, but too much of it is probably set in stone.
Yeah I hear ya, High Moon found the characters voice much better in this game. It ended right when it was starting to get really interesting where they were taking the fiction and characters.
Still maybe because I'm just getting older (and distinctly remember a time when Transformers was gone and seemed like it would never come back) but I'm just grateful we got these games at all.
If two is all the High Moon game series ends up being, I'm ok with that. At least they were two really solid fun games and didn't overstay their welcome. Easily the best Transformers games ever made.
What I would love to see is something more squad based that emphasizes more of the team nature of how the auto While these games were fun, I think it's tough leverage the giant cast of characters Transformers has in a shooter game. Something Squad based or maybe even a RTS or SRPG with an even heavier story focus. Probably wouldn't sell nearly as well, But I'd like it. :)
@slag: I don't know about an RTS, but I'd certainly be happy with another shooter that evolved the squad-based elements and would allow for more than two non-named characters to be on screen. As far as representing the entire Transformers Pantheon, let's be honest: even the show didn't do that. Been too long since I've played a good tactical squad based shooter.
I didnt play much of this game, probably up to the third chapter, but they totally ruined Optimous Prime.
One second he talks about saving lives, the next he is talking trash and wishing death all while mowing down hordes of nameless alien robots. Then there is a cut scene where he feels sorry and you are supposed to feel sorry because the nameless alien robots that are colored red are dieing.
I get that it was supposed to invoke emotion, but they didn't even try to set up that emotion aside from the beginning where a certain character dies, and the narration of the plot where they try to invoke your nastaliga.
After that they don't set up the story at all, there is no build up to why the war is happening, there is no emotional attachment to these characters because they don't do anything aside from yell different lines and shoot.
I understand that it is probably really hard to make robots emote. but when you are asking me to be angry at one kind of robot, and sad for another robot that looks exactly the same, but colored differently you need to show why one is different then the other, why one robot is better then the other.
Thats my rant, and as I said, its probably really hard to make robots emote.
That's true the shows never have (although the original series at least cameoed a huge number of characters), but that's also something that I think games can do better than TV.
High Moon certainly tried in their own way and they did a decent job, by rotating playable characters and in War for Cybertron have squads of three. But it just felt weird for Optimus Prime to be charging to the decagon without a squad of Autobots with him like you know he would have.
Have you ever played Valkyria Chronicles? One thing I really liked about it was the huge roster. Now granted there were 5-7 characters with any real depth or relevance to the main story but every solider you could use in your army had unique voice acting, design and bios. Something like that is what I'd like to see instead of random Generabots and Generacons fleshing out the world past the main characters. I don't need in depth features on the tertriary characters but it'd be nice if they were the world fillers so to speak. That would be a good way to leverage the cast to the benefit of the game.
Also one thing I've never liked about previous Transformers games is the sheer amounts of enemies you face and that the named characters usually end up being bosses. I'd rather have fewer but bigger fights with every opponent being a named character. Add some weight to the encounters instead blowing through 800 nameless bots. Squad vs Squad.
And lastly i didn't mention this earlier. but one thing I used to love about Transformer fights was the giant robot grappling. High Moon obviously knew about this, evidenced by the final boss fight. So if they could institute a robust hand to hand element i think it would add another last missing piece of the Transformers magic.
So I guess I want a cross between Freedom Fighters, Valkyria Chronicles and Sleeping Dogs starring the Transformers. Not asking for too much eh?
maybe that would be way too expensive to make, but man that would be sweet if they ever did.
It's too bad you quit there, since I thought the Optimus chapters were easily the worst in the game. Chapter 4, when it switched to Cliffjumper & Jazz is where I went from being lukewarm on the game to being totally on board. I noticed what you did and felt they didn't get the Optimus character right. You're absolutely right there was a really weird dissonance where Optimus was bemoaning violence and then simultaneously messing dudes up. It was very strange.
Peter Cullen did a good job voice acting him as only he can , but the writers did no favors with what they were giving him to say.
As far as the setup goes, I think they were banking on you playing the previous game which touches more on what you noticed was missing. Still I agree they could have done quite a it more to develop the characters.
oh and spoilers
Bumblebee got better. He's a main character in the Transformers: Prime cartoon show which follows the events of this game.
: I haven't played Valkyria Chronicles but I know what you mean by it. In general I think you've brought up two of the major issues with modern game design that I've been harping on in these forums for months or years. The first is getting rid of the arbitrary cap on the number of allies you bring into battles. This goes as much for RPGs as for transformers: don't give the player more characters than he can use unless you have a really good reason why half of them have to stay home. And the whole "So as not to attract attention" excuse only gets you so far.
The other is the inappropriate use of cannon fodder in games that should have a greater focus on small scale fighting. In recent memory, aside from Transformers, Max Payne, Tomb Raider, and Spec Ops: The Line have all had this problem. The root of the problem is that shooting has gotten too easy with modern controls and the focus on realistic settings makes bullet spongy enemies pretty tough to swallow. I think the only solution is to increase the realism in the difficulty of aiming and reloading a weapon. That would, in turn, make melee solutions more ideal.
I agree with you about the cannon fodder in transformers for that reason, but at the same time, I don't know if your suggestion is the solution either. The source material leaves them in kind of a Catch-22 situation.
The cartoon was defined by large scale laser battles from cover where almost no one hit anything. The movie (which I think we can agree is the real inspiration for these games) is characterized by battles that are almost as decisive and final as real life, where a single well placed shot can put a bot out of action. It'd probably be possible to build a game around that dynamic - there are certainly enough characters in Transformers to manage it, but you'd dig yourself a real hole lore-wise with all the transformer corpses that would be left behind after a decent length game.
Yeah Ally cap is silly. I always assumed the real reasons behind it were popularity based ( to allow the player the choice to not use characters they didn't like if they wanted to) and perhaps memory resource related. I agree it seems unnecessary.
re: cannon fodder- I personally don't think it's the shooting as much as it's the getting shot. If getting shot once or twice by AI would take you out, most of those games would get real tough real quick. Still I know what you mean. I bet it would be likely is financial suicide for Crystal Dynamics , but if say Tomb Raider only had ten enemies to kill but made them into tenser encounters more like it used to be back in the PS1 era, it wouldn't bother me in the slightest. Personally I prefer the old "tomb raiding" aspect of the series, that seems to be out of favor at the moment. Never been a Spec Ops guy, although Max Payne is pretty fun. It's amazing how over the counter pills can cure bullet wounds for that guy.
Now I see the transformers fiction as not a catch 22 in this case and here's why. Transformers are often really hard to kill especially in the really old stuff,it's pretty common trope in the fiction that characters get rebuilt after getting blown up. Granted lately death has been more permanent in the Movies and such probably for dramatic sake. Even now though what actually kills a Transformer is really inconsistent. They can be basically be completely disassembled and rebuilt with 99%new parts to no ill affect. It used to be you had to crush the Brain Module to actually finish the job, I think, but after Sparks entered the picture in Beast Wars now it's usually crushing that.
But even if you take a character out in a mission, there are plenty plausible ways to bring that character back for a later one without really contradicting the universe's fiction very unlike say if you were doing a game featuring humans. Heck you could do it over and over and it would fit with the fiction just fine. The old "Stasis Lock" excuse was the comic series' favorite mechanism to get rid of old characters without upsetting fans back in the 80's. If memory serves I think Sunstreaker and SideSwipe among others were in StasisLock for roughly 85% of the initial series run. It was a nice callback to see it used in this game as well. Maybe a cheap story telling mechanism for a comic book, but very handy immersion tool for a video game.
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text:
I just got home from the grandmommy of all blogging conferences, BlogHer14. I could say a million things, but I'll limit myself to just these few words. Blogher Review
I'm $till Standing
Unlike years past–Blogher11, BlogHer12, BlogHer13–where I sort of wondered what the hell I was doing going to BlogHer, I absolutely had an agenda this year. A very personal agenda.
I've been blogging since 2008, and I'll be damned if some silly "business" (and I use that term loosely) fallout will destroy me, or keep me from blogging. In fact, since the demise of Generation Fabulous, my readership is at an all-time high. And I've already made more money in the past six months than I've ever made before in a whole year. I just didn't make that money from blogging. Which is fine by me. I prefer it that way. And apparently so does my growing audience of readers.
Despite some stomach flutters on my way to San Jose, I was happy every single minute of the entire conference. Besides looking and feeling more fabulous than a 52-year old woman has a right to—it's incredible what working out and eating right can do for you as opposed to sitting on your ass all day jerking everybody off in the daisy chain that is today's social media–I loved seeing so many old friends again.
Maybe "old" isn't the right word when you consider friends like Alexandra Williams from fitandfun.org who can still do this.
And having my dance card freed up recently made room for so many new friends.
On my first night in San Jose, I met Dawn Quyle Landau from Tales from the Motherland. We had a great time getting to know one another. (That empty nest can be a mean bitch, can't she, Dawn?) And I adored finally meeting Molley Mills from A Mother Life—she and I are fitbit aficionados…
and Linda Roy (pictured below) and Lance Burton from Lefty Pop.
There are so many others, most of whom I can't remember right this moment. This is why I HATE mentioning anyone on my blog. I don't want to hurt anyone's feelings by excluding them. Just know that if we met and shared a story or a laugh together my old, addled brain is thinking warm thoughts about you right now.
Never Say Never. Except This Time.
It's probably a bit premature to say this, but unless I have a real and present financial reason, I don't think I'll ever go to another BlogHer again. This isn't because I didn't have a great time–I did–I had a spectacularly great time–but because it's one pretty damned expensive girls' weekend that just doesn't live up to its hype anymore. Not for me, anyway. Don't get me wrong. I am very grateful to the founders of BlogHer for putting on this party, year after year. And I hope and pray that my comments don't make me seem ungrateful. It's just that I think I'm over it.
The Recap
Going a couple of days early and hanging out with Julie Chenell DeNeen from Fabulous Blogging was the best part of the whole damned week. Next time, I'll just plan on a little trip with her, and skip the conference.
When I found out she'd never been to San Francisco, we ventured into the city together to see the sights. She wrote about our adventures here.
Once the conference started, it was obvious that her community, The Bloppy Bloggers, was the group to belong to this year. That girl has got it going on. Plus, she doesn't snore. And she understands when you ask her to get out of bed in the middle of the night, after a long day of networking and conferencing, to take pictures for your "How to Make Jello Shots in a Hotel Room" tutorial. It was a win-win-win!
Thursday, July 24th
The Pathfinder Day session I attended on Thursday was a complete waste of time and money. I wish I could get a refund. The two authors who spoke on how to get your book published were pretty awful. Why bother having these sessions at all when the panelists don't know anything about how to find an agent? (They both shared with us how "lucky" they were and how agents just found them. That's helpful!) And do I really need to spend two hours of my life listening to what two adult people who aren't my kids did in junior high? Seriously?
The Pathfinder Day lunch was great. The prime rib was perfect. But I couldn't bring myself to go back and listen to those two yahoos talk about their sophomore year in college, and how they are just so fantastic that agents and publishers are tripping over themselves to publish them, so I cut out and went to lunch with Nancy Hill from Reason Creek, Carol Cassara from CarolCassara.com, and Kim Tackett from Fifty-Fifty Vision. Now, that was time well-spent!
On a sad note, I did lose my water bottle that I got from my trip in March to the UNFoundation in Washington, D.C. It was bound to happen eventually, but I'm going to mourn the loss of that water bottle for a long, long time, may it R.I.P.
Friday, July 25th
Friday morning's keynote speaker, The Bloggess, was delightful. It's obvious why she's so successful. She's charming and funny. And she makes mental illness look like something we should all aspire to. I loved her.
As usual, I'm lame as hell when it comes to getting pictures at these things of myself standing next to celebrities, but Dawn Landau got one.
I'm pretty upset now that I didn't stand in line and get The Bloggess to sign my boob like she did for so many of my friends.
I was going to tell you about the morning session I attended on Friday, except I can't remember what it was. I could go refresh my memory by looking it up, but I think the fact that I don't remember anything about the session, or what I learned there, or who the speakers were, is the review that matters. Take from that what you will.
The other session I attended was about how one goes about joining a non-profit Board of Directors. The moderator, Cherylyn Harley Lebon, of harleylebon.com, and speakers, Martha Rebour, Shot@Life, Morra Aarons-Mele, of Women Online, and Shivani Garg Patel, from Samahope were all very well-informed and engaging. I learned a ton. My takeaway? I'll never have enough money to join a non-profit Board of Directors.
But it was fascinating hearing about how the other half lives. And I learned a lot about how the world actually words, which is nothing like what my poor parents, who were raised in the housing projects in Louisville, Kentucky, taught me.
Last year, after feeling like I'd missed the entire damned conference whoring myself around to get party invites that—except for one that resulted in a now infamous pair of Louboutins—turned out to be a big, fat waste of my dwindling life, I vowed that this year I would not attend one outboarding event. BlogHer made it easy-peasy for me to keep my promise by doing whatever it was they did to make sure there weren't any (that I knew about, anyway).
Sadly, the parties that did happen this year were very different compared to previous years. It is obvious that things are seriously changing for Blogher. What this means for bloggers and the future of BlogHer remains to be seen, but I suspect that the days of football field-sized vendor halls, and the ginormous bags of swag, are over. The once-legendary room drops this year consisted of two mirror stickers, and one tiny cupcake made out of lentils. Take from that what you will.
I did like the mirror sticker though. Here's the selfie I was supposed to take with it.
This sticker and picture are meant to promote a self-esteem project being done by a band called The Mrs. Here's the song they performed for us. I like it.
Saturday, July 26th
Saturday, I slept in. What can I say? I'm old, and I was tired.
This meant I missed Arianna Huffington's keynote breakfast speech. The irony of this is that later I heard that Huffington's #1 piece of advice on the secret to success that she dispensed to the bloggers, who'd dragged themselves out of bed at the crack of dawn to hear her speak, was to get more sleep. As always, I'm ahead of the curve.
So now I'm just going to say out loud what everyone else was saying in whispers. Having Arianna Huffington speak at BlogHer is like having Darth Vadar give the pre-battle motivational pep-talk to the Federation on the eve of the battle of Endor.
Thank you, Arianna Huffington, for making your millions off of the work of writers who you don't pay. Brava! Well done!
Huffington spoke about the future of something called the social web, or some such thing. Even without a crystal ball, or hearing her speak, I predict a future where thousands of writers from here on out can expect more non-payment for their work. Excellent job, Arianna! How about a standing ovation?
Can you see me rolling my eyes from where you're sitting?
But Enough About Arianna Huffington
I attended TWO sessions on Saturday, BOTH of which I remember. YAY!
The first was a session about what to do when it is time to change the direction of your blog. This was informative and helpful. I definitely enjoyed the speakers, Ana Flores, Latina Bloggers Connect, August MacLaughlin, Girl Boner, Carrie Forrest, Carrie on Living, and Melanie Feehan, Melanie in the Middle.
Changes are coming for me and my blog. In light of my piece on labor pain that I wrote for Scary Mommy, which was shared almost 42 THOUSAND times on Facebook, it is obvious that I'll be writing more about that topic in the future.
The Future of Personal Blogging
The most important session I attended during the entire conference was on the future of personal blogging. The discussion leaders for this 2.5 hour session, billed as a "Mini-Conference," were A'Driane Nieves, from Butterfly Confessions, Elan Morgan, better known as Schmutzie, and Kristen Howerton from Rage Against the Minivan.
I know people keep saying that personal blogging is dead, but they are dead wrong. The standing-room only crowd that showed up for this session proves that personal blogging is very much alive, if maybe not quite so well now that it is infected with Ponzi-scheme-ism and Amway-itis.
But with any luck, maybe the fact that brands have finally figured out that throwing huge sums of money at bloggers at blog conferences is a pig in a poke will mean that crappy ad-copy masquerading as blogging will die the death it so richly deserves. At least one can hope.
Jello Shots
On Saturday night, after the last official party, Julie and I hosted a little party of our own. No brands sponsored us, although Jello should send us a check, I suppose. Lots of people showed up. Jello shots were slurped. A good time was had by all.
Here's Tammy Bleck, from Witty Woman Writing, Me, Julie, and Aussa Lorens, famous hacker, ninja, hooker, spy, bidding you adieu from our FABULOUS hotel room bathroom on the 7th floor of The Fairmont in San Jose.
Good times, BlogHer! I'm going to miss you.


text:
List Entry Summary
This building is listed under the Planning (Listed Buildings and Conservation Areas) Act 1990 as amended for its special architectural or historic interest.
Name: PALACE HOUSE
List entry Number: 1094430
The building may lie within the boundary of more than one authority.
County: Hampshire
District: New Forest
District Type: District Authority
Parish: Beaulieu
National Park: NEW FOREST
Grade: I
Date first listed: 08-Oct-1959
Date of most recent amendment: Not applicable to this List entry.
Legacy System Information
The contents of this record have been generated from a legacy data system.
Legacy System: LBS
Asset Groupings
This list entry does not comprise part of an Asset Grouping. Asset Groupings are not part of the official record but are added later for information.
List entry Description
Summary of Building
Legacy Record - This information may be included in the List Entry Details.
Reasons for Designation
Legacy Record - This information may be included in the List Entry Details.
Legacy Record - This information may be included in the List Entry Details.
17/18 Palace House
Medium-sized country house incorporating monastic gatehouse. Mid C14
gatehouse, converted to hunting lodge c1540 for Lord Wriothesley, extended
early C18 when moat and turreted wall built around site, restored and much
enlarged 1872 by A Blomfield. Coursed rubble stone, stone dressings, old
plain tile roof. Plan of large usual gatehouse of 2 storeys and attic, 2
span by 2 bays deep, set gables on with 1 x 1 bay part set back on one
side; Blomfield added to far corner of projection 4 storey stair tower (to
serve his main range), on other side single storey addition with projecting
porch over moat and behind projecting slightly lower wing, with C16 turret
on junction; behind gatehouse Blomfield built long double pile slightly
lower range with crosswings either end, built on side and end walls above
moat and incorporating turrets raised to 2 storey (this range projects 3
bays beyond stair tower against gatehouse). South elevation has gatehouse
part to LH and set-back to RH C19 main range. Gatehouse has, in centre,
stonework of 2 moulded order pointed archway, filled in with C19 hipped
stone-roofed oriel window with light either side, each light ogee trefoil
with transom. Each side tall sloping-topped buttress, and square-headed
window of 2-trefoiled-lights under one and 2 x ½ quatrefoils. Above
archway tall canopied niche between pointed 2-trefoiled light windows.
Over corbel table and 2 kneelered gables with 3-light mullion windows. On
roof ridges C19 square-shafted stacks with moulded heads. To LH of
gatehouse single storey part with 5-transomed-light mullioned window and
4-centred doorway and corbelled crenellated parapet. Inside gatehouse
front part was originally a porch to central carriageway and footway on its
LH, both arches visible in central wall of gatehouse proper, RH doorway
C16. Both parts vaulted with tierceron star vaults. RH part of porch was
room with C15 fireplace and square-headed 3-trefoiled light window and
pointed door. On 1st floor were 2 chapels with, originally 2 pointed
arches between, and piscinas and C14 east windows. VCH; Vol IV; 1911;
p652. Buildings of England, Hampshire, Pevsner; Penguin; 1966; p96-7.
Country Life, 1906, p702-7.
Listing NGR: SP4095100000
Selected Sources
Books and journals
Doubleday, AH, The Victoria History of the County of Hampshire and the Isle of Wight, (1911), 652
Pevsner, N, The Buildings of England: Hampshire and the Isle of Wight, (1967), 96-7
'Country Life' in Country Life, (1906), 702-7
National Grid Reference: SU 38730 02445
The above map is for quick reference purposes only and may not be to scale. For a copy of the full scale map, please see the attached PDF - 1094430 .pdf
The PDF will be generated from our live systems and may take a few minutes to download depending on how busy our servers are. We apologise for this delay.
This copy shows the entry on 19-Sep-2017 at 12:44:47.
End of official listing


text:
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text:
Set and get cookies in the browser or in node with
In your browser code with browserify:
var cookie = ;var times = || 0;cookie;
times will increment every time the page is reloaded.
var cookie = ;
Return a new cookie object with
.get() and
.set() operating on
document.cookie should be a non-referentially transparent setter/getter combo
like the DOM's variant where assignment with optional path and expiry creates a
new cookie in the getter as a key=value pair.
Return the cookie value for
Set the cookie at
key to
value with optional parameters
expires and
To unset a cookie, use a date in the past, ex:
{ expires: new Date(0) }
With npm do:
npm install cookie-cutter


text:
3 NORTH SIDE (4-3) — Redskins have easiest path to a SAC championship of three contenders.
4 WAYNE (5-2) — I can hardly wait for the season-ending Wayne vs. Snider match-up.
5 BISHOP DWENGER (5-2) — Saints bounce back with respectable performance against state power.
6 SNIDER (5-2) — Panthers drive all the way to Elkhart to find their offense.
7 CARROLL (5-2) — 14 days ago, Chargers were in 6th place in NHC. Now it looks like a lock for 2nd.
8 CONCORDIA LUTHERAN (4-3) — Cadets are a 2-point conversion away from having won 5 straight.
9 HOMESTEAD (5-2) — Shakiest performance by Sparty D all season long. At worst time.
10 WOODLAN (4-3) — Warriors fare very well against ACAC behemoth, but still lose.
11 EAST NOBLE (5-2) — Knights will have rest of NHC cheering them on next week against New Haven.
12 CHURUBUSCO (7-0) — Not saying much, but that was Eagles' most impressive win all year.
13 HERITAGE (5-2) — Is this what the Patriots have become? A consistently good program?
14 COLUMBIA CITY (3-4) — Eagles' D to be tested yet again next week vs. Carroll.
15 SOUTH SIDE (2-4) — Archers would have much better record in lesser leagues.
16 BLUFFTON (4-3) — Tigers have to shore up defensive woes in order to win again.
17 BELLMONT (3-4) — Braves get a week respite against Barons next Friday.
18 ADAMS CENTRAL (4-3) — Flying Jets will have one last shot at a W next week at Bluffton.
19 NORTHROP (2-5) — Bruins defense has been, and will continue to be, beaten into submission.
20 NORWELL (2-5) — Sparty's trip to Ossian now doesn't look so easy.
21 GARRETT (4-3) — Victory over Starfires snaps 2-game skid. Another starts next week.
22 SOUTH ADAMS (2-5) — The road doesn't get any easier next week (at Woodlan) for Starfires.
23 BISHOP LUERS (0-7) — The woes all start up front with shaky line play by Knights.
24 DeKALB (0-7) — What else is there to say about Barons at this point? Nothing, is the answer.


text:
BOSTON ( TheStreet) -- Thomas Steyer, the billionaire environmentalist and founder of hedge fund Farallon Capital Management, has made a big bet on a rebound in the economy by buying energy and industrial stocks, including El Paso ( EP) and Goodrich ( GR).Steyer founded Farallon Capital in 1986 and has served as the fund's managing partner. Based in San Francisco, Farallon has about $22 billion in assets and uses numerous strategies ranging from credit to value to merger-arbitrage investments. The hedge fund has a disciplined approach to preserve capital, focusing on achieving risk-adjusted returns.
|Thomas Steyer of Farallon Capital Management.


text:
Regardless of what any of us want, the whole idea of making video games is to make money. As it stands, it would seem that Sony isn't making it easy for anyone. This could be bad news for the PS3's future.
According to Namco Bandai President Takeo Takasu, due to production costs, each PS3 game will have to sell at least a half-million units to be able to make a profit. For comparison, the Wii costs half as much (which means half the sales for profit). The news is in stark contrast to the PS2, where some games that sell 100,000 titles are able to make money.
The sales levels required just to make money on the PS3 should be troubling for gamers. Sony's current Greatest Hits requirements are 400,000 copies, so it is very possible that a GH title could have lost the publisher money (and we could start seeing more of them as publishers scramble to break even). Will the high development cost prove to be prohibitive to the developers of niche games that made the PS2 a true global hit?


text:
Airport Full Body Scanners
View Single Post
Join Date: Oct 2007
Location: Ocean Springs Mississippi
Posts: 400
You do raise an interesting point regarding the actual amount of radiation exposure from the TSA scanners. I agree with you and think that it would be completely irresponsible for our government to condone the use of radiation on innocent folks every day if there was any chance that it could be more harmful than we have been led to believe. That being said, I have read some information from both sides of the issue, and as a physician, I can honestly say that I am not the least bit worried about the radiation received during the scanning process. If we were to suppose that the TSA calculations were off by a factor of 10, the amount of radiation exposure received would still be quite small compared to other sources and in my opinion, no cause for concern. Again, this is just my opinion.
I am definitely not an expert and I am happy to admit that you probably have much more experience than I in dealing with radiation safety (I am completely serious about that). I am merely approaching the topic from the standpoint of radiation exposure that I am familiar with, e.g. a standard chest x-ray. That radiation must penetrate deep enough to shoot completely through the entire body to a plate on the other side. It also shoots partially through more solid structures like bones. This requires a very short pulse of high energy radiation. A CT scan exposes the patient to dozens of times as much radiation as a chest x-ray, and fluoroscopy sometimes even more. Having seen thousands of patients exposed to sometimes dozens of CT scans over a relatively short period of time, I am not too worried about the TSA scanners. CT scanning has been in routine clinical practice for more than 20 years and to my knowledge, there have been no substantial increases in cancer rates as a result.
Again, I did not go through the math and do any specific calculations, I am just using my general understanding of radioactivity that is used in medicine to form a very general opinion. I AM DEFINITELY NOT AN EXPERT!!! It is entirely possible that I am wrong, so please don't anyone file a lawsuit against me.
Just my two cents,
View Public Profile
Send a private message to Wheels87
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text:
The Research Department is the primary resource and catalyst for advancing research
at the Texas Tech University Health Sciences Center. Our mission is to promote and
support research by providing high quality service to investigators, foster new research
initiatives, promote the prevention of disease and the treatment of illness, motivate
and educate future leaders in health sciences, and serve as an advocate for the value
of research in an educational setting.
We provide leadership, direction, and management of research administration, infrastructure and services, and oversee the operations of the following areas: Office of Research, Research Integrity Office (RIO), Quality Improvement Review (QI), Laboratory Animal Services Center (LARC) and the Office of Sponsored Programs (OSP).
Page last updated on: August 22, 2017 at 10:08 am


text:
Cannot mount volume.
Unable to mount the volume.
Cannot obtain lock on /media/.hal-mtab
I use KDE!
Many workstions and few servers running on Fedora or Scientific Linux professionally.
Using LINUX to do some scientific 3D-stuff.
I'm RHCT
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text:
Haven't joined yet? Join MYX |
In case you missed it last week, here's MYX Celebrity VJ Sue Ramirez on Pinoy MYX! Watch as she treats us to OPM videos from Rivermaya, Shehyee, and the amazing Darren Espanto!
Of course, the best part is Sue herself! Who can be that cute and hot at the same time?! Her bubbliness is infectious; I'm smiling as I'm typing this! Watch the episode below:
Can't get enough of MYX Celebrity VJ Sue Ramirez? Catch her on Mellow MYX this week!
Did you enjoy watching Pinoy MYX with VJ Sue? Tell us in the comments!


text: On Fri, Jun 08, 2001 at 04:32:49PM -0600, Todd Miller wrote: > Is there a way to determine if a user has admin rights on the server. I > have written a utility to send server announcements and I want to disallow a > user from logging in to the utility if they do not have admin rights. The > utility connects using the JabberCOM.DLL. (before I start, apologies if I'm on the wrong track) Although stpeter has answered referring to the jabber.xml config file, I'll assume that your utility doesn't have access to this, and you want to do it programatically (as you mention the JabberCOM library). It's an interesting question that (to me) has a few wider implications, over and above the 'how can I find out if a user has admin rights' question. But to this question first; there are at least two approaches - try to discover before logging on, or try to discover after logging on. The latter is easy if a little crass - log on and try to do something that requires admin rights (e.g. an iq:admin 'who' query) and check for error messages. It's also not that neat either, as - even though you don't have to end presence, to avoid an avalanche of offline messages that the user isn't going to get a chance to deal with - having already logged on, it's too late - we're already logged on, which was to be avoided. On the whole, not good. The former is a bit more interesting. Can we make a query before logging on to find out about admin rights? Not really, as the only query namespaces that are honoured before a session is started on a stream are the iq:auth and iq:register namespaces. All other elements are buffered until authentication has taken place. But consider the iq-get request made in the iq:auth namespace. This (optional) step allows the client to discover the authentication methods supported for that user: SEND: <iq type='get'> <query xmlns='jabber:iq:auth'> <username>qmacro</username> </query> </iq> RECV: <iq type='result'> <query xmlns='jabber:iq:auth'> <username>qmacro</username> <password/> <digest/> <sequence>123</sequence><token>ABCDEF12</token> <resource/> </query> </iq> JSM modules can register for the iq:auth namespace and will tack on tags to the result for an iq-get announcing their readiness to handle an authorisation check via an iq-set. The <resource/> tag is tacked on the end too, which got me thinking. Taking advantage of the current lack of optional/mandatory determination in the result tags, would it be possible to write another module that would tack on extra information? I'm certainly not suggesting this is the right solution at all - I'm ready to be shot down in flames for trying this out, but I just did it as a learning exercise. I created a new JSM module mod_dj_admin.c : #include <jsm.h> mreturn mod_dj_admin_yip(mapi m, void *arg) { if(jpacket_subtype(m->packet) == JPACKET__GET) { if(js_admin(m->user,ADMIN_READ)) xmlnode_insert_tag(m->packet->iq,"read"); if(js_admin(m->user,ADMIN_WRITE)) xmlnode_insert_tag(m->packet->iq,"write"); } return M_PASS; } void mod_dj_admin(jsmi si) { js_mapi_register(si,e_AUTH, mod_dj_admin_yip, NULL); } and added it into JSM's <load/> area, below mod_auth_0k. Now a SEND: <iq type='get'> <query xmlns='jabber:iq:auth'> <username>qmacro</username> </query> </iq> will return extra tags <write/> and / or <read/> depending on the admin rights of the username in the query, something like this: RECV: <iq type='result'> <query xmlns='jabber:iq:auth'> <username>qmacro</username> <password/> <digest/> <sequence>123</sequence><token>ABCDEF12</token> <read/> <write/> <resource/> </query> </iq> This way, a client could determine admin rights before deciding whether to go ahead and authenticate. Anyway, the other side to this question comes from other systems that I'm more familiar with: SAP, for example, has a mode where you can prevent anyone logging in except admin users (e.g. SAP* or DDIC). I'm wondering whether this would be a useful feature for Jabber too, as more and more services are added and those services administered using the Jabber protocol itself, with the ultimate goal not to have to take the server down. Of course, there's another part of this to be addressed - in the switchover from 'normal' mode to 'admin' mode, there will be 'normal' users left connected, who will have to be 'thrown off'. Anyway, I'll stop here for now, otherwise I'll start to bore everyone to death. Has anyone else considered such 'mode switch' functionality? dj on his 4th cup of coffee this morning


text:
BaseCollection Class
Provides the base functionality for creating data-related collections in the System.Windows.Forms namespace.
For a list of all members of this type, see BaseCollection Members.
[Visual Basic] Public Class BaseCollection Inherits MarshalByRefObject Implements ICollection, IEnumerable [C#] public class BaseCollection : MarshalByRefObject, ICollection, IEnumerable [C++] public __gc class BaseCollection : public MarshalByRefObject, ICollection, IEnumerable [JScript] public class BaseCollection extends MarshalByRefObject implements ICollection, IEnumerable
Thread Safety
Any public static (Shared in Visual Basic) members of this type are thread safe. Any instance members are not guaranteed to be thread safe.
The BaseCollection class is not intended for use by application developers. Application developers should use CollectionBase instead.
The BaseCollection class implements the ICollection interface.
Classes that derive from the BaseCollection class include:
Namespace: System.Windows.Forms
Platforms: Windows 98, Windows NT 4.0, Windows Millennium Edition, Windows 2000, Windows XP Home Edition, Windows XP Professional, Windows Server 2003 family, .NET Compact Framework
Assembly: System.Windows.Forms (in System.Windows.Forms.dll)