text:
Lesinurad Interaction Study With Ranitidine
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Drug: lesinurad 400 mg Drug: ranitidine 150 mg Drug: lesinurad 400 mg + ranitidine 150 mg
|Phase 1
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
|Official Title:
|A Phase 1, Open-Label, Drug-Drug Interaction Study to Evaluate the Potential Effects of Ranitidine on the Pharmacokinetics of Lesinurad in Healthy Adult Male Subjects
- PK profile of lesinurad from plasma and urine [ Time Frame: Days 1 and 6 (Sequence 1) or Days 2 and 7 (Sequence 2) ]
Profile in terms of Cmax, Tmax, AUC, CL/F, t1/2
Cmax: maximum concentration; Tmax: time to reach max plasma concentration; AUC: area under the concentration-time curve; CL/F: total body clearance corrected for bioavailability; t1/2: apparent terminal half-life
- Incidence of Adverse Events and Changes in Laboratory, Electrocardiogram, and Vital Signs Parameters [ Time Frame: 6 weeks ]
- PD profile of lesinurad from serum [ Time Frame: Days 1 and 6 (Sequence 1) or Days 2 and 7 (Sequence 2) ]Profile in terms of serum urate concentration
|Study Start Date:
|July 2013
|Study Completion Date:
|November 2013
|Primary Completion Date:
|September 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Sequence 1 fasted
Day 1: Lesinurad 400 mg once daily (qd)
Day 5: Ranitidine 150 mg twice daily (bid)
Day 6: Lesinurad 400 mg (qd) + ranitidine 150 mg (bid). Ranitidine dosed at -2 hours predose and 12 hours postdose of lesinurad.
Day 7: Ranitidine 150 mg (bid)
|Drug: lesinurad 400 mg Drug: ranitidine 150 mg Drug: lesinurad 400 mg + ranitidine 150 mg
Experimental: Sequence 2 fasted
Day 1: Ranitidine 150 mg (bid)
Day 2: Lesinurad 400 mg (qd) + ranitidine 150 mg (bid). Ranitidine dosed at -2 hours predose and 12 hours postdose of lesinurad
Day 3: Ranitidine 150 mg (bid)
Day 7: Lesinurad 400 mg (qd)
|Drug: lesinurad 400 mg Drug: ranitidine 150 mg Drug: lesinurad 400 mg + ranitidine 150 mg
Detailed Description:
|Ages Eligible for Study:
|18 Years to 55 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- body weight ≥ 50 kg (110 lbs) and body mass index ≥ 18 and ≤ 30 kg/m2.
- Screening sUA value ≤ 7.0 mg/dL.
- free of any clinically significant disease that requires a physician's care and/or would interfere with study evaluations or procedures.
- Subject has no clinically relevant abnormalties in vital signs, ECG, physical examination or safety laboratory values per the Investigator's judgment.
Exclusion Criteria:
- history or clinical manifestations of significant metabolic, hematological, pulmonary, cardiovascular, gastrointestinal, neurologic, hepatic renal,urological, or psychiatric disorders.
- history or suspicion of kidney stones.
- undergone major surgery within 3 months prior to Day 1.
- donated blood or experienced significant blood loss (> 450 mL) within 12 weeks prior to Day 1 or gave a plasma donation within 4 weeks prior to the Screening visit.
- inadequate venous access or unsuitable veins for repeated venipuncture.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01908257
|United States, California
|Cypress, California, United States, 90630
|Study Director:
|S. Bradley, MD
|Ardea Biosciences, Inc.
|Responsible Party:
|Ardea Biosciences, Inc.
|ClinicalTrials.gov Identifier:
|NCT01908257 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 23, 2013
|Last Updated:
|January 8, 2014
Additional relevant MeSH terms:
Ranitidine bismuth citrate
Anti-Ulcer Agents
Gastrointestinal Agents
Histamine H2 Antagonists
Histamine Antagonists
Histamine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Uricosuric Agents
Gout Suppressants
Antirheumatic Agents
Renal Agents
ClinicalTrials.gov processed this record on September 21, 2017


text:
I am scheduled to have breast aug (rapid recovery) in 11 days and my ps does not believe in pain meds. I am beginning to panic as I am reading a lot of people needed strong pain killers for a few days post surgery. Is it normal to just rely on advil as he is instructing?
No Pain Meds, Post Breast Aug?
Doctor Answers 19
Do I need pain medication after breast augmentation.
The so called quick recovery breast augmentation consist of mostly electro cautery dissection under direct visulisation and avoiding blunt dissection. I use this technique and I must admit that patients require less pain medicine after surgery. Pain medication is used only if it's needed and there is no harm giving the patient a prescription for a pain medication in case she has pain, as people's pain tolerence can vary. I am sure your doctor will agree to give you a prescription if you ask him.
Pain Medication
If you are concerned about pain and he will not prescribe you pain medication you might want to ask about an injection called Exparel that helps numb the surgical area for up to 3 days after surgery. Patients normally experience the greatest amount of pain in the first 3 days so this injection can help get you through to hardest part. Best of luck to you!
Breast Augmentation
Learn more: http://arcplasticsurgery.com.au/breast-augmentation-information/
You might also like...
Is pain medication required after breast augmentation surgery
I would say that there is not set rule on whether or not pain medication is required after breast augmentation surgery. Patients have individualized needs for post op pain management and I have seen a wide spectrum over my years as a plastic surgeon. It is certainly possible that you would not require stronger pain medication than Advil. I would recommend that you discuss your concerns with your plastic surgeon and ask him/her if stronger pain medications would be available if you find that your pain is not adequately controlled with Advil or other over the counter pain medications.
Learn more: http://gayosoplasticsurgery.com/implants-faq.html
Pain Medication for Breast Augmentation?
I have added a video about all of this for you as well as a web link.
I hope that helps.
Best regards.
Learn more: http://www.drwindle.com/breast-augmentation-24-hour-recovery
Waking up With Minimal Pain after Breast Augmentation
After Breast Augmentation,most of my patients wake up reasonably comfortable - there is a reason for this - the use of intraoperative injection of local anesthetic into the surgical area and muscles being repaired.
For most of my patients, I use Celebrex and Acetominophen (does not make you drowsy and less chance of nausea) plus intraoperative use of Exparel. Exparel is a very long-acting local anesthetic that lasts approximately 3 or more days following injection and great for Tummy Tucks and other surgeries. Not only does it prevent pain but also most muscle spasms. It lasts the same length of time that a pain pump lasts and will therefore take the place of a pain pump. This means patients can enjoy the same effect of a pain pump, but without any catheters and no pain pump to carry around.
Exparel will be available for those concerned about minimizing discomfort after surgeries such as tummy tuck and breast augmentation.
Exparel costs the same as a pain pump and produces the same result but with less hassle and works great.
Narcotics are used only as needed (as cause nausea, vomiting and constipation as frequent sided effects).
Learn more: http://drnichter.com/exparel-long-lasting-local-anesthetic/
Pain after breast augmentation
Most of my patients do not need much pain medication after a breast augmentation. Done correctly, it is not typically a very painful procedure. However, if you are concerned, discuss this with your surgeon. If you have reservations about needing stronger pain medication and not having any available, seek a second opinion. Surgery and recovery are very individual.
Post medications
Hi! Thank you for your question,
I am Dr. Speron, a proud member of both the American Society of Plastic Surgeons (ASPS) and the American Society of Aesthetic Plastic Surgeons (ASAPS). I am also certified with the American Board of Plastic Surgery.
After breast surgery, your board certified plastic surgeon will usually prescribe pain medications such as Vicodin or Percocet and a muscle relaxant such as Valium. The Valium helps relax the muscle which may have rippled from being stretched by the implant. Your plastic surgeon may have a reason on why Advil would suffice for pain medication. It is important to discuss your post medications with your plastic surgeon or ask your pharmacist about any drug interactions. I advise that you consult with your board certified plastic surgeon and follow further post op instructions.
I have provided a link below for additional information and before and after pictures.
If you have any further questions, please feel free to call us at 847.696.9900.
Best of luck and have a great day!
Dr. Speron
Pain Medications after Augmentation
I would suggest you simply ask for a script for stronger pain pills just to have as a 'security blanket' but with the steps we take these days to make the procedure as pain-free as possible don't be surprised if you find you don't need them
Terrence Scamp
Pain Meds following Breast Augmentation
The method of breast augmentation I do is also rapid recovery. However, I give all my patients oral pain medications. These are generally used the first day, occasionally the second day and before bed for a day or so longer. Some patients use almost none of the medications and take Tylenol instead. I encourage my patients never to take Advil, Aleve, aspirin or other non-steroidal antiinflammatories as they increase the risk of bleeding or bruising. This varied need and the general inability to predict who will need what.is why I give all my patients pain meds.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.

subset: commoncrawl


text:
Robbery, attempted carjacking in Columbia Heights
Police are investigating what began as a road rage incident and ended in a robbery and attempted carjacking in the heart of Columbia Heights.
The early morning attack was unsettling to residents. Four men with guns tried to rob and carjack another car filled with people, but the victims fought back, followed their attackers, found police and now the robbers are all behind bars.
At 3 a.m. there weren't as many people out on 14th Street near Park Road, according to the police report. A 34-year-old D.C. woman was driving a Lexus with three other people--two men and a 41-year-old woman.
Police say four men in an Oldsmobile got upset about how the woman made a turn in front of them so they followed the Lexus and when the woman stopped the car, the men jumped out, walked up to the Lexus, pulled out guns and started to fight with the men in the Lexus.
The attackers pulled the woman out of the drivers seat and robbed everyone. One of the attackers yelled, "Take the car!" One tried but the Lexus was in park, so the suspects all jumped in their Oldsmobile and fled the scene.
The victims followed the suspects. Along the way, they saw a D.C. police officer and waved him down. They found the suspects on 9th Street NW and Butternut Street NW.
"I heard all this screaming and everything," said neighbor Vera Majett.
The Majetts were getting ready for church when they saw what was happening outside. They applauded the victims.
"I love it. I love it. I am glad by did. These people get away with too much," Majett said.


text:
Larry Birkhead, one of the central figures in the Anna Nicole Smith drama, is returning to the witness stand to give jurors the inside story of his life with the late Playboy model and her drug use.
Birkhead, the father of Smith's daughter, Dannielynn, was to testify Friday for a second day as a prosecution witness in the drug conspiracy trial of two doctors and Howard K. Stern, the man who once fought him for custody of Smith's child. Also watching in court has been Virgie Arthur, Smith's mother who also sought guardianship of baby Dannielynn when Smith died.
Birkhead, who won the battle with DNA tests, was being asked about Stern's role in Smith's drug-fueled existence. Birkhead said he saw Stern give her medicine when she didn't feel well and knew he was picking up prescriptions for her at the pharmacy. Birkhead also said that when he once hid the powerful painkiller from Smith, Stern called him and asked where it was.
"I was told by Howard she needed it to live, the Methadone," he said.
Prosecutors planned to have Birkhead identify videotapes of Smith before and during an appearance at the American Music Awards in which she appeared to be drugged.
Birkhead testified Thursday he saw her taking numerous prescription drugs but that she told him she was not an addict.
He said that from the time he moved in with Smith in late 2004 he was concerned about her excessive use of medications and questioned her about it.
"She would say, 'I'm in pain. I'm not a drug addict,'" Birkhead recalled.
When he suggested she was taking too many drugs, she replied, "I have a high tolerance because I'm in pain."
An issue that has emerged in the three-week-old trial is whether Smith was an addict or was dependent on drugs for pain.
Stern, Dr. Khristine Eroshevich and Dr. Sandeep Kapoor are charged with prescribing to an addict as well as conspiring to provide excessive opiates and sedatives to the celebrity model. They are not charged with causing her 2007 overdose death in Florida.
With prosecutors focusing on Stern, his sister, Bonnie Stern, testified Thursday under a grant of immunity from prosecutors. She identified e-mails in which Smith pleaded for her to have drugs sent to her in the Bahamas. But Bonnie Stern said she didn't remember sending anything.
Howard K. Stern's lawyer, Steve Sadow, asked about the personal relationship between his client and Smith.
"She was his everything," Bonnie Stern said of her brother. "I only wish I would meet someone that loved me as much as he loved her."


text:
Michael J. Fox
Fox's big break was in the popular '80s television show Family Ties. He also starred in the hugely successful Back to the Future trilogy, not to mention many other films, before returning to TV in the '90s in the smash hit series, Spin City.
AppealChick-baiting is somewhat beside the point for Michael J. Fox. Sure, many women were undoubtedly attracted to Alex P. Keaton and Marty McFly back in the '80s, but Fox's romantic fame is limited almost solely to his wife of fourteen years (and counting...), who was also Alex P. Keaton's first love. Rumor has it that he did, however, have the requisite '80s fling, with Facts of Life tomboy Nancy McKeon.
SuccessMichael J. Fox began his career at the age of 15, with the CBC series Leo and Me. Following that, his key early roles were in the made-for-TV film Letters from Frank, the Disney feature Midnight Madness and the TV drama Palmerstown, U.S.A. In 1982, he took on his most famous role, as Alex P. Keaton on Family Ties, which lasted until 1989 and won him three Emmy Awards and a Golden Globe. In 1985, Fox starred as Marty McFly in the blockbuster Back to the Future, and reprised the role in parts two (1989) and three (1990).
The same year that Back to the Future madness took off, Fox underscored his image as a teen heartthrob with the title role in the comedy, Teen Wolf. He followed these up with roles in popular late '80s and early '90s films like Light of Day, The Secret of My Success, Bright Lights, Big City, Casualties of War, and Doc Hollywood.
After a less successful period and a hiatus, he returned in fine form with parts in The American President and on the sitcom Spin City, for which he earned an Emmy, three Golden Globes, two SAG Awards, a People's Choice Award, and a GQ Man-of-the-Year Award. In December 2002, Fox was honored with a star on Hollywood's Walk of Fame.
His most recent role as the voice of Stuart Little in the hit family comedy of the same name has introduced him to an entirely new audience, in the original film and the 2002 sequel.
Since announcing in 1998 that he has Parkinson's disease, he has established the Michael J. Fox Foundation for Parkinson's Research, a charitable organization that seeks a cure for the disease.
Michael J. Fox BiographyMichael Andrew Fox was born June 9, 1961, in Edmonton, Alberta (he later adopted the "J" as a tribute to character actor Michael J. Pollard). Since his father, William Fox, was an army official, the family moved around a lot during Michael's early childhood. They settled near Vancouver, British Columbia, when William retired in 1966. About the constantly changing settings, Michael said that an "army brat" must "either find a way to get attention or become a wallflower." Of course, he chose the former.
a small start
When the family settled down for good in Burnaby, Fox engaged in a typical upbringing. He loved hockey but it became clear that his height would hinder any professional ambitions (today he is 5'4"). He also loved acting but not in any serious manner. That is until, when he was fifteen, his drama teacher suggested he audition for a local CBC (Canadian Broadcasting Corporation) television production called, Leo and Me. He won the part and his career was underway.
Though Leo and Me only lasted 13 weeks, Fox was off to a great start. He dabbled in local theater and, in 1978, won a role in the American made-for-TV film, Letters from Frank. Famous entertainers Art Carney and Maureen Stapleton were also part of the cast, and their appreciation of and support for the young actor created opportunities for his career. Just after his 18th birthday -- and prior to completing high school -- he left Canada for Hollywood.
bright lights, dark times
Initially, Tinseltown was great for Fox. He landed parts in the Disney feature Midnight Madness (controversially, the company's first PG-rated film) and in the impressive new weekly drama Palmerstown, U.S.A., produced by Roots author Alex Haley. He also had brief appearances in popular shows like Trapper John, M.D. and The Love Boat. In short, he had as good a start as any young actor could hope for.
In 1981, Palmerstown, U.S.A. was canceled, and Fox's luck began turning downward. Caught up in the early stages of success, he developed poor spending habits, and was in debt some $30,000 when he lost his regular job. He was forced to move into a garage apartment, and to sell off his sectional couch one piece at a time. Living on macaroni and cheese, becoming unhealthy and depressed, Fox considered moving back home to Canada.
that's alex p. keaton to you
But before moving home, Fox decided to at least try to get back in shape. And so he did by attending an audition for the role of Alex P. Keaton, the amicable Republican son of liberal parents in the NBC show Family Ties. His winning the role compelled him to stay in California, but the show started out slow in the 1982 season. Typical of the network at the time, NBC decided to give it some time to develop.
By the end of its third season the show hit full stride, and became one of the most adored and highly rated sitcoms of the '80s. Alex, in particular, was a beloved character, and he became more or less the focal point of the show. With typical humility, Fox took every opportunity to direct attention to his less-appreciated co-stars. In 1986, he earned his first of three Emmy Awards for Family Ties, and took home the Golden Globe in 1989. By all accounts, Michael J. Fox was one of the biggest stars on television.
the future's so bright...
But TV was not his only area of expertise. Early on in Family Ties' run, he starred in two made-for-TV movies, High School U.S.A. and Poison Ivy. Then, in 1985, he broke out onto the silver screen in a major way. Apparently, Michael J. Fox's manager, Gary David Goldberg, neglected to tell him about the offer for Back to the Future for fear of tearing him away from Family Ties. It was only after director Robert Zemeckis fired Eric Stoltz from the lead role that Goldberg informed Fox, who quickly took the role.
Back to the Future was a smash hit, and it propelled Fox's film career for a number of years. He had earlier filmed a B-movie called Teen Wolf, which was released two days after Back to the Future and so, riding its wave, went to number 2 at the box office. Fox reprised his role as Marty McFly in two subsequent sequels, and they remain his most successful film ventures.
movie time, family time, down time
The line between Michael J. Fox and Alex P. Keaton became blurred when the actor married his character's first love on Family Ties, actress Tracy Pollan, in July 1988. They now have four children -- a son and three daughters (including a set of twins), and as far as Hollywood families go, they beat the odds.
Following Back to the Future, Fox enjoyed a string of successful films, such as Light of Day, The Secret of My Success and Bright Lights, Big City. He surprised audiences and critics alike with departure roles in Casualties of War and The Hard Way.
In the early '90s, Fox relaxed his schedule to spend time with his family, after which he had a string of disappointingly unsuccessful films like Life with Mikey, For Love or Money and Where the Rivers Flow North..
At this point, Fox decided he needed a rest. In 1994 he took a substantial break from acting, hired a new agent, and got his career back on track with 1995's The American President. It was the beginning of a new phase, equally as productive as the Family Ties glory days.
back to the boob tube
In 1995, while filming The Frighteners in New Zealand -- a long way from home and family -- Fox yearned for the consistent schedule and geographical stability of the television business. It did not take him long to land another fan favorite role, as Michael Flaherty, Deputy Mayor of New York City, in ABC's Spin City. The role garnered him an Emmy and three Golden Globes, among a slew of other awards, as well as the respect of fans and peers.
In 2000, Fox threw in the Spin City towel due to a change in priorities, two years after his announcement that he had been suffering from Parkinson's disease since 1991 (while on the set of Doc Hollywood, he noticed an uncontrollable tremor in a pinky finger).
leading the fight
Since the disease has no known cure (as of yet), the actor set up the Michael J. Fox Foundation for Parkinson's Research and has concentrated his efforts on helping find a cure. He has rallied many celebrities to his cause and has continued to attract the admiration of the masses with his persevering good nature.
Even with his busy schedule in the fight against Parkinson's, Michael J. Fox continues to lend his talents to the big screen, as the voice of the lovable family mouse in the blockbuster film series, Stuart Little.
Show comments


text: I like games like Baldur's Gate II / Diablo II / Morrowind on the PC. Also like most of the Final Fantasy series. I don't like the generic RPGs like Zenonia and Dungeon Hunter on android. I like RPG games that have a bit of depth (either in mechanics or in the world itself). Can someone suggest some android RPGs that I might like? I have a Galaxy Tab 7 Plus (1.2ghz). Price doesn't matter.


text:
Name: Darth Vader
Collection: The Vintage Collection (Basic Figures – VC93)
Status: Darth Vader is an all-new figure.
Source: A New Hope
Availability: April 2012
License: Hasbro
Retail: $9.99 USD
Accessory Details: lightsaber
VC92 Anakin Skywalker [The Clone Wars Realistic Style]
VC93 Darth Vader
VC94 Imperial Navy Commander
VC95 Luke Skywalker (Hoth Outfit)
VC96 Darth Malgus
Our Visual Guide Database:
STAR WARS is Trademark ™ Copyright © Lucasfilm Ltd., all rights reserved. This Web site is in no way supported or maintained by Lucasfilm, and is meant for informational purposes. This site is maintained by the staff of JediTempleArchives.com. All Visual Guides, images, and content are the property of JediTempleArchives.com, © 2004-2017 and may not be reused without permission. Please do not direct link to any of the content on this web site. Click here for our Image Use Policy.


text:
I had a KTP Laser Treatment 10 weeks prior which has left some post-inflammatory hyperpigmentation, red, scratch-like depressions where I blistered ( the area she treated for capillaries), and some brown marks which were originally faint hyperpigmentation marks. I have a reunion and wedding to attend in 7 weeks and want to improve my skin. I have access to Fraxel Restore or IPL photorejuvenation. I am so nervous to touch my face again, but am also so upset at the way my skin looks. Any advice on PIH treatment would be appreciated.
How to Treat Hyperpigmentation After KTP Laser Treatment?
Doctor Answers 1
Conservative treatment warranted after hyperpigmentation and scarring after KTP laser
Thankfully, the affected areas should get better with time. It is critical to obtain consistent daily sun protection with high SPF sunscreen and reapply every 2 hours between 10am and 4pm. Consider topical antioxidant vitamin C serum in morning prior to sunscreen and alternating regenerative TNS cream with gentle prescription-strength retinoid every other night to facilitate tissue remodeling. Prescription-strength bleaching cream may be added later if hyperpigmentation persists. IPL should be avoided and Q-switched Nd:Yag laser such as Spectra Laser should be considered. Refrain from ablative fractional laser resurfacing within the next 3 months as the pigmentation and/or depressions may worsen.
Learn more: http://www.drwilliamting.com/Cosmetic_Dermatology.html
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


text:
How Our Faces Age (And a Few Misconceptions)
Facial aging is a fascinating subject to study and understand. It isn't a fun subject to live with, but it is a natural part of life that everyone will face. So why is it that as we get older we look, well, older? The answer is that a number of small changes combine to make you look aged. These small changes can be categorized into three main groups: skin surface defects, volume loss, and skin redundancy. Most people have all three in varying ratios and the combination creates an overall aged appearance.
The first thing that usually happens is skin surface imperfections. These imperfections include fine lines and hyperpigmenation, both of which contribute to an aged appearance. The primary culprit for these is the sun. The more time you spend in the sun, the more damage you cause your skin. Of course, you can minimize this with regular, quality skin care. Proper cleansing, moisturizing, and most importantly – sunscreen – will limit the sun's damage to your skin. If you like being tan, spray tanning is much healthier for your skin.
The second thing that people experience, but may not notice is volume loss. More often than not, when a patient comes in with loose skin, it is not that the skin is stretched but rather that the substance or fill underneath is dissappearing. Your skin is designed to wrap around your face. As you lose volume in the face, the skin loses its tension and starts to look saggy. So why do we lose volume? As we age our body breaks down the collagen in our skin (the connective tissue that gives our skin thickness and elasticity), the fat underneath the skin dissolves, and even the bones in our faces resorb. To further complicate this problem, our face doesn't lose volume evenly across the face. Every person loses volume at different rates in different areas.
The third and final problem is skin redundancy. This is usually the last sign of aging to occur and can be limited by proper maintenance of the first two issues. Over time, the tension and tautness of the skin starts to relax, resulting in skin redundancy. This most severe facet of aging is treated surgically, whereas the first two signs of aging can be treated non-surgically.
After knowing what causes your face to appear aged, we can begin treating. To create a natural looking appearance, you have to treat all three issues individually. The skin surface can be treated with laser treatments and medicated creams. The volume loss is corrected with fillers or fat injections. Finally, the skin redundancy is treated with a surgical lift or tightening (facelift, blepharoplasty, browlift). By applying all the tools we have to treat each problem individually (and in moderation), we can achieve a younger, natural look that still looks like you, just a younger you. Where people often run into problems is when they try to treat all three problems with just one solution. This is most commonly seen in people who have treated all of the aging effects with just facelifts, leading to the "windswept" look (think Phyllis Diller, Nancy Reagan, Joan Rivers).
Remember, you didn't age in one way, so don't expect to reverse it using just one method. And, don't underestimate the power of lasers and volume replacement in facial rejuvenation. They should usually be the first treatments against aging. And, when you are finally ready for a facelift explore all options as there are less invasive surgeries like the Changes Rapid Lift which can achieve your goal with less downtime and cost.


text:
This could be the start of your journey
Jeugd met een Opdracht Heidebeek is een zendingsgemeenschap gericht op het toerusten en mobiliseren van jonge mensen om wereldwijd 'God te kennen en Hem bekend te maken'. Wij zijn vertegenwoordigd in meer dan 180 landen met meer dan 20.000 vrijwilligers. Er zijn allerlei mogelijkheden om betrokken te zijn binnen JmeO en dit kan jouw begin zijn van een geweldige tijd.
Door alle studenten van de scholen, de deelnemers van verschillende activiteiten en de negentig medewerkers is het op JmeO Heidebeek altijd gezellig en vol leven.
Of je nu mee doet met een school, op zendingsreis gaat, of het team versterkt als staf, vele mogelijkheden liggen open. Stap uit in geloof en doe mee aan zending op Heidebeek!
Upcoming Events
- Seminar: Unlocking the PropheticOct 20, 2017 - Event
- Bijbel3daagse: Intro Profeten & AmosOct 23, 2017 - Course
- Samen Meer Huwelijksweekend – - – De BetteldNov 17, 2017 - Workshop
- Open dag/week DTSNov 21, 2017 - Event
- Bijbel3daagse: Paulus & RomeinenNov 29, 2017 -
- Yes, I do !Mar 9, 2018 - Workshop
- School of Frontier Missions 2018Apr 6, 2018 - School
Het sociale netwerk van Heidebeek
School voor Frontier Zendi…Posted in Discipleship Training Center
(English) Testimony Erne a…Posted in Children at Risk school
(English) Testimony Abdula…Posted in Children at Risk school
Into the world of the Bibl…Posted in Bijbel Zomer Cursus
VerhalenPosted in GO Teams
Teach one teacherPosted in Children at Risk school
learning from kidsPosted in Children at Risk school
I am Marjolein, serving with YWAM since 1986. Married to Paul. Together we have been blessed with three wonderful children. We have been on an ongoing adventure of walking on water following Jesus. We have been serving in the area of Family Ministry in Nepal, India, New Zealand and now in and from The Netherlands. Sharing God's heart and plan for marriage and family to whoever wants to listen.
I'm blessed with a wonderful family. Jantien and I have three kids. After having done a DTS (2001) and SBS (2002) I joined YWAM at the end of 2003. Teaching the Bible is my greatest passion. I believe the Bible draws us into God's Story and equips us for His mission of setting up His Kingdom.
Hey I'm Gertrude, married to Willem Jan, mother of 2 beautiful children: Loïs (2010) & Noah (2011) . Before YWAM I was a teacher at a highschool & I taught the fine arts & art history. September 2008 we did our DTS in Manilla, Phillipines. Photography, painting/sculpture, dancing, reading are the things I like to do. Together with Willem Jan we have the priviledge to lead the Generations DTS.
After being out of the country for some years I have grown even more fond of my flat, wet, green, homeland with it's many cows and bikes. It's good to be back! Discovering the School of Biblical Studies (SBS) was a total surprise for me and doing it an absolute privilege. I am looking forward to share with others what has been given to me by staffing BFL.
My name is Diana. I'm from Georgia The Country, not the State . I did my DTS in 2006 in Georgia after that I joined Ywam there. It has been a great journey . Now from 20-Th of June 2013 I'm here in the Netherlands and I have a big privilege to staff classic DTS starting on Sept. 2013 and I'm looking forward to it. So I'm going to take the best out of the school.
Hello, I am Janneke Duursma. Born in a family of six children, almost 54 years ago. I gave my life to Jesus in 1981, the best thing that ever happened in my life!! It is my desire that people get to know who they are in Christ and their inheritance in Him! Than they really will live in the freedom that God has meant for them.
Hi there! My name is Jonathan and I am married with Ava from Australia. I am working with the DTS for the last two years and in January I will be involved with Mercy & Justice DTS. I can't wait to start and to work together with other people who loves Jesus and who wants to make Him known!
Hi, My name is Seth and I'm 20 years old. In Januari 2015 I did the Mercy & Justice DTS at YWAM Heidebeek, this was great! Now I have the privilege to staff the Mercy & Justice DTS. I have a passion for Jesus and l'm looking forward what He will do in the DTS! That we will know Him and make Him know:)
Hi, my name is Lisette and I am 27 years old. In September 2013 I did a classic DTS at YWAM Heidebeek. During my own DTS my passion for missions grew. It's exciting to work together with God, it's always an adventure. Last two years I worked as staff with the Classic DTS. I am looking forward to meet all of you, I love it to see people going deeper with God because He is revealing His heart!
Hello my name is Theo, 25 years old. I did my DTS last year, and now i'm gonna work as staff. I love to see young people so passionate about Jesus. Surrendering their lives to God. And i'm glad and honored that i can play a piece in that. My passion is to bring the Fatherheart back to the children. This coming season is a new start for me! God is great!
Samuel Joel
Hi, I am Samuel Joel, married to Mariana and have two children Ruchama and Channiel two beautiful children. My heart is to make disciples, people put in their free gifts and talents. Along with Mariana, we are concerned with Ywam since 1981 to 2000 we moved to Assen. To continue the work with Ywam. I will lead this DSC!
Marleen Pruim
I am Marleen Pruim. I was born in 1983 and I work since 2007 at Heidebeek. That's also where I met my husband, Stefan. Together we have 2 beautiful kids (Jaron/2013 and Mattias/2015). I'm very thankful for our beautiful family. I work at the accounting department and I'm involved with LUZ. My heart is that Heidebeek will be a blessing to many people!
Hi, I am Karin. In 1987 I did my DTS in Amsterdam and I worked there as staff till 1995. Then I came to Heidebeek. The last 13 years I worked with the Biblical Study Center and part of my ministry was Biblestorytelling for adults. Now I work with the M & J dept. I work with the womensgroup LUZ which is focussing on refugee- and other migrant women. In this setting I also tell Biblestories.
I'm a web designer by heart and leader off the communications department. I'm with YWAM since 1996, traveled the world, lived in the States and now part of Heidebeek since 2005. I'm also a father of three (two girls and a boy) and husband of a beautiful woman named Rebecca. Guilty pleasures: B&J New York Super Fudge Chunk, gaming, golfing, football and secretly drinking out of a milk bottle.
No information available
No information available
No information available
I'm Joke, I work at the Mercy&Justice office and especially with Mobile Mercy. I did my DTS in 2009 and in 2010 and 2011 I staffed the Mercy Ministry DTS. In 2012 I did the Children at Risk school in Brazil and did my practical year from march 2013 till march 2014 in Brazil as well. I have a heart for children in need.
Annemiek van Middelkoop
Ik ben 39 jaar en heb een hart voor het versterken van het huwelijk en gezin. Na in 2007 mee te hebben gedaan met Family Camp van JMEO. Heeft God ons hier visie voor gegeven om hier meer betrokken bij te raken. In 2013 hebben we een Family Ministry School gedaan bij JMEO, Heidebeek en in 2015 zijn mijn man en ik hier Fulltime bij betrokken. We hebben samen 4 kinderen in de leeftijd van 2- 11 jaar.
Often we can read in the Bible Gods' care and love for the poor and needy. I believe that with the little things that we can do many will be helped and encouraged. My prayer is that many will experience Gods' love when we share the Gospel with them in very practical ways.
Hi there! My name is Marjan and I did my DTS in Denver in 2004. I came to YWAM Heidebeek in February 2011 and now I'll staff the Discipleship Summer Course! I like sun, chocolat, music, travelling, icecream, tea, photography, summer nights, cities, walking, the smell of rain, sunsets, secondhand shops!.... Oh, and I live in the most beautiful house! I am blessed!
Through young missionaries, Jesus made a difference in my life. And with the relational youth work we do with GO Teams I hope other young people start being the difference wherever they are.
No information available
No information available
No information available
No information available
Hi! since 2010 i work within Heidebeek to build on a focus on refugees. We started in 2014 international womangroup LUZ.
I'm a Photographer and I love it to magnify God in the images I make. I'm with YWAM Heidebeek since early 2012 and greatly enjoy the life and work here at the base. I've done a number of GO Teams and eventually my DTS with YWAM. And, I come from the beautiful province of Zeeland, and I am blessed with a healthy dose, sobriety and Humor!
Hey Hallo, nearly seven years I may work with Youth with a Mission. After my DTS I followed the SBS and that has captured my heart. I find it amazing to see others grow as they go through school or courses, grow in faith, make choices that make them grow and flourishing in God's plan for their lives. and I believe that the Bible plays a major role in getting to know God better.
Hey, I am Remco and I'm 29 years young. I am married to Ellen and we have a wonderfull son; Joah! In 2009 my wife and I did the Mercy Ministry DTS at Heidebeek. We work at Heidebeek since 2010. I am involved in the DTS and in maintenance at the base. Before I started at Heidebeek, I worked as a procesoperator on a chemical plant in Rotterdam. I'm looking forward what God is going to do through us!
No information available
No information available
Willem Jan
Life is such a precious gift, every day I want to enjoy it! I'm married for about 9 years with Gertrude and I have the privilege to be daddy of 2 wonderful kids, Lois and Noah. Some years ago we did our DTS in Manila.. You can make me happy with a cool glass of coca cola, bitterballen and french fries on the saturday (or another day)
Hello! My name is Leoni, I'm 33 years old and since 2011 I work at YWAM Heidebeek. I love to work with the DTS. It's great to work with young people and to see what God is doing! Also in the mini DTS God has a great change to influence people! I'm married with a wonderful man, Daniel, who also works at Heidebeek and we have a beautiful son, Rens. We love life living together.
Hi, I'm Hillebrand. I'm working with Heidebeek since September 2000. After working in the Biblical Studies Center, I and my wife Aafke staffed DTSes for many years. The last 6 years we are involved as intercessors in the Prayer & Worship Center. Besides this, we are involved with "beten & bewegen"- a prayer movement in Germany.
No information available
No information available
I am Tlana Fanai married to Betty Fanai-van Dijk togther we have 3 beautiful kids, I come from The Northeast INDIA. Did DTS in 1996 since than I am working with YWAM. My wife and I work with DTSes many years in India & South Africa. I also work with mercy ministries in India and South Africa. I am with Prayer and Worship ministry. It's my passion to worship God, and to lead people into worship.
I'm Agnes, married to Henk and mother of Myrthe, Hannah and Joshua. My passion is to see people grow into a life breathing relationship with our Father. I love to spend time with people and share life together.
Hello, my name is Ellen Griffioen! In 2009 I did the Mercy Ministry DTS together with my husband at Heidebeek. In 2010 we started working at Heidebeek. Before that I worked as a primary school teacher. I am 28 years old, married to Remco and mother of Joah. It is wonderful to be involved with the DTS and see God at work!
Marieke Hesseling
My name is Marieke Hesseling. I'm married to Bart and I'm 25 years old. For some years I work with great pleasure with Related, part of Evangelism Center. And in the end of August this year we're expecting a baby!
Hey, I'm Aldert Bouman from the beautiful province of Noord-Brabant. Two years ago I did a Classic DTS (it was really awesome) and this year I will be again one of the leaders in the Football DTS . I discovered that I have a heart for missions and find it a great opportunity to combine my two biggest passions.
Linda de Regt
In 2001 I did my DTS and that changed my life and my relationship with God completely. Since 2014 I live and work at YWAM Heidebeek, at this moment at the Mercy and Justice office. My passion is to bring God's love to those who suffer and lost all hope, by being the hands and feet of Jesus in this world. Another passion I have is horseriding, I love riding together with my daughters in the forest.
Hello, I'm Florence originally from Cameroon. I'm married to a handsome man from Togo, Nestor Tsala. My passion in life is to see Heaven invade Earth, to equip & release people to impact the world. Currently I lead the Prayer & Worship Center at Heidebeek, and I'm also the school leader of the School of Intercessory Prayer. It's really fun to serve the Lord, come join us! ;-)
No information available
Youth & Evangelism; the pefect combination ! Just started a Youthcenter in Heerde; de Werf
to be announched
I am always up for an adventure and a good cup of coffee. Nothing bring me more joy than getting lost in a new place with friends. Nothing inspires me more than seeing peoples lives being transformed by the truth. I teach Bible because i believe it can change nations. I train Bible teachers so that more people can know how awesome God is. And it is tons of FUN! I like fun :)
No information available
Hi, my name is Jonathan and I'm from Belgium! I did my DTS at Heidebeek in 2005 and I also did the School of Biblical Studies. I'm married to Ingeborg and we have two kids, Joëlle & Jesse. Before I came to work at Heidebeek in 2010, I worked as a pastry baker. I left these nice sweets behind me to work with the DTS. God is doing wonderful things and I am glad that I can be a part of this.
Peter van Middelkoop
Hi, my name is Peter I work at the Family Ministry department here at Heidebeek. In the summer of 2015 we started here. Actually back in 2007 we did our DTS here and in 2013 The FMS. I think its important that Christian couples get good teaching how to keep your married running. On the basics trust, understanding, respect and love. And all of this founded in Christ. God bless your marriage.
I am a proud husband to a wonderful wife, father of three amazing children and honored to play a part in Gods story through history. I love to help people grow into a relationship and their Godgiven destiny in His Story. It's nice to be a close witness of the transforming power of God in peoples lifes. I love fellowship, fun, patatje kapsalon, Chinese food and life itself.
Petra Willemstein-van Reeuwijk
Bringing Gods truth to change lives is my passion, to see that happen I joined the Biblical Studies Centre february 2012. Besides digging in the Word, I love to go for a walk in the forest with my husband. For the rest: I love pink, chocolate and having lots of fun!
Hi there, my name is Joas Jongenburger, am 24. I did my own DTS in 2013, what causes that I may work now at YWAM Heidebeek with a lot of pleasure. I'm glad that I took this amazing adventure with God. I'm looking forward what God will do this season.
Together with my wife and family we are part of the Heidebeek community now for 15 years. I´m a mechanical engineer and leading the maintenance department. Besides that I´m the projectleader for our new building project. It´s a joy and privilege to co-work with God in order to build hearts and places with our God given talents, to see people saved
René Houtman
Blessed with my wife Ralda and 4 kids, 1 daughter-in-law and 3 grandchildren. Active in pastoral care, psychotherapy, marriage counselling and bible lectures. Theology always remains the greatest discipline there is, but to be able to combine it with therapy is a great privilege.
No information available
My YWAM journey started in 1985 in Sweden. Then it took me to the Philippines and Micronesia before it led me to Heidebeek. While doing my SBS in 1995 I got hooked on the word and work with the Biblical Studies Center since. It's a joy to get people excited about God and his word.
YWAM missionaries
The leaders and staff of this school we won't put on the internet out of safety reasons. All leaders and staff have worked (and are still working) for many years abroad on the frontier missionfield. We are very glad we can have such experienced people come and lead this school. For contact with the schoolleader please email: firstname.lastname@example.com
Born in the beautiful Swiss alps, I came over Mexico (DTS) Canada (SBS) to work with the "Bible for Life" school at Heidebeek. I love good laughs, cheese, and Tony's Chocolonely. I am very passionate to see people discovering God's heart and mind, His beautiful story of redemption, as they study the Bible by themselves.
No information available
It touches me if people are in need, but somehow didn't get the right help. Therefore it's special to me to be able to bring some hope and a helping hand, so that they might experience Gods' love.
Dick Brouwer
With my wife Ulla and our four children we have been involved with YWAM Heidebeek since 1988. Some of my roles have been in area of communications and as Heidebeek base leader (11 yrs, until Jan 2007). The past years I am primarily involved in pioneering/coordinating 4K12Provinces (regional)teams, RescueNet and since Oct 2007 also serving as YWAM Netherlands national leader.
Marieke Blokland
Hi, my name is Marieke. I married in October 2012 with Wieger. In my own DTS I discovered many aspects of the character of God. That is why I am looking forward to discover together who God is and who he wants to be for you and me!
No information available
Hi, I'm Wimski van der Garde. As a campaign coordinator of The God Story I am involved with the Evangelism Center of YWAM Heidebeek. I have a clear focus on Europe, a continent in need but not lost! Passing on the Hope in Europe through youth work, events and public activities, I may every time witness how peoples life's get restored by the power of Jesus Christ. There is hope for Europe!
Hey! My name is Jody. I'm married to Jelle. I'm working with the DTS. It's great to see how God is transforming lifes of students during the DTS! I desire that more and more young people will live out what's on Gods heart.
Lisette van den Heuvel
My name is Lisette and I'm 22 years old. In January 2015 I did my own DTS. It was an amazing time where I got to know God better and where my heart for missions became bigger. De poverty and injustice in the world is something that touches me. That's why I love the focus of the Mercy & Justice DTS. I'm looking forward to staff the DTS!
Jelle Maneschijn
Hi! My name is Jelle, happily married to Jody and we have a wonderful son called Daan. This is going to be my fifth DTS, including when I was a student. For me it is amazing to work with the DTS! Great to see God at work in the lives of the students and to see Him working through the students! I am looking forward to this DTS, so see you then!
Hi I'm Jenni! I've been with YWAM since 2006. I'm married to Wim and we have 2 children. I work in the Prayer & Worship Center and my passion here is to equip people in the prophetic, with a focus on worship. My husband and I also have a passion to help people discover the power of truth, being transparent & the transformation that follows after those things.
Hey, I'm Bart. Studying the Bible is all about pursuing God. That's why I am also enthusiastic about our ministries. I am looking forward to dig together in God's Word to discover more of His heart and get in awe of Him.
I also enjoy playing soccer, biking through the forest and drinking coffee with friends.
Hello, Welcome to the website! In 2007, I did my DTS at heidebeek. For years I worked with people with disabilities. I used to be a teacher in South-Africa from 2010 till 2012. Now I am back at Heidebeek and I am looking forward to the Generations DTS! Greetings, Rianne
Hi I'm Ita from Indonesia. In September 1996 I did my DTS and since then I have been working with YWAM. First I worked with YWAM Bali and since November 2009 with YWAM in Holland. I worked in many different ministries, but for now I love to work in Hospitality ministry. Some characteristics of mine are: friendly, happy, adventures and I love children, but more then anything I love God!
No information available
Hi, I'm Jacolien, 32 years old, married to Franc. In 2013 we did our own DTS here at Heidebeek, and right after that we joined YWAM. Before that I worked as a teacher in a small village called Kamerik. Since 2014 I work with the Mercy & Justice DTS. For the summer of 2017 I will be involved in the mini DTS! I'm looking forward to what God will do in these weeks, because whoever seeks, will find!
No information available
Hi there, my name is Stefan. I'm married with a beautiful women called Marleen and together we have 2 sons. I did my DTS in Perth, Austrailia. From 2008 onwards I work here at the Heidebeek base. My passion is to see a lot of young people being released into world missions. Further: Football, going for a drink, bbq, volleybal, craft beer and Champions League.
No information available
Hi, my name is Wies, born on 1st feb. 1964. Since 1996 working with YWAM. I've also worked with Mercy Ships MV Anastasis & with YWAM in South-Africa. In november 2012 I started working with YWAM Heidebeek. From februari 2013 focussing on Member Care & hospitality. I enjoy good healthy food, cycling, reading, jazz, markets, musea, nature & outdoors, gardening, singing in a gospelchoir, cats & dogs.
Daniel Wierstra
Hi! My name is Daniel Wierstra, 32 years old and work since 2012 at Heidebeek. I work at the Maintenance team and together we take care of our buildings. Besides that I coordinate our touring car, so that all the students arrive at the right place, I do that together with 7 other drivers. I'm married with a wonderful woman, Leoni and together we have a great life! I also like to watch soccer on tv
Wieger Blokland
Gods Kingdom will eventually breakthrough, completely and everywhere. Partnering in Gods mission for this world is what inspired me a lot in my DTS. It is my desire that this mission will be a guidance for myself and my family, out of His grace. I will be co-leading the Mini DTS 2017. Blessings and welcome to YWAM Heidebeek!
Hi, I'm Martin. I'm working at Heidebeek for about six years now, where I have two jobs. I'm working as staff in the Classic DTS, which I enjoy a lot. DTS is an amazing time. During mine God really turned my life upside down! I'm also in the IT department, where I take care of the computer maintenance. Two completely different things but I enjoy them both. I like both people and technical stuff.
Fedde Ypma
From 1975-today jobs as reporter and editor at daily news papers. From 1997 on also working with YWAM Heidebeek, first ten years in communications, from 2009 in (mainly) Family Ministry. That work was partially born out of King's Kids, the ministry my wife joined in our first decade at Heidebeek. During that time we also led some GO Teams and King's Kids campaigns to countries all over the world
When I was 11 years old I wanted to a missionary. For many years I was a Bible teacher in public schools teaching kids age 8-13. In 1993 I did my DTS in Amsterdam. For over 10 years I was a missionary in America. In 2007 the Lord led me to Heidebeek. I am called 'to serve those who are called to go'.
Hi, my name is Seraina. Like every swiss I love cheese and chocolate. Even more than that I enjoy spending time with friends, I'm always up for a cup of coffee. But truly heart beats for the nations and teaching the Bible and that's why I'm part of Bible for Life.
Hi, I'm Froukje. Since a few years I'm part of the Mercy & Justice office. I'm leading the department of Justice Projects. Every time I hear that injustice is being done towards mainly women and children my heart is touched. How much more is it affecting Gods heart! I hope that together we will be strong in the fight for loving your neighbour and doing justice!
Hi, I am Paul, serving with YWAM since 1986. Married to Marjolein. Together we have been blessed with three wonderful children. We have been on an ongoing adventure of walking on water following Jesus. We have been serving in the area of Family Ministry in Nepal, India, New Zealand and now in and from The Netherlands. Sharing God's heart and plan for marriage and family to whoever wants to listen.
A missionary
No information available
Terry Sherman
I've now lived longer in Holland than in the U.S.! The thing that makes me happy is if I can encourage someone - in any way. Since 2002 I've become passionate about changing people's perspective about raising support by teaching the biblical/spiritual foundation.
No information available
In Spannum (Friesland) I was born, 73 years ago. I'm married to Barbara, blessed with two daughters, both married, a grandson and -daughter. I've been a minister in the Dutch Reformed Church for 20 years. Barbara and I did our DTS on Hawaii in 1984. Since 1985 I'm part time involved in the life and work at Heidebeek, since 1996 deeply involved in the BSD. Hobby's » celebrations and thrillers
Hi there! Nestor is always on the go. Better said on the move. The best way to say it might be " he is in the place called there". Florence tries to help him live in the present. Is that working? However together they make a powerful and a lovely couple. Passionate about the presence of God which they pursue arduously, they equip people to release Heaven on earth.
Hi, my name is Martine. Before I came to Heidebeek I worked as a speech and language therapist in a practice and elementary school. I enjoyed my job very much! However, I have a heart for the lost and needy and feel called to reach out to these people on the mission field. I'm very excited about the M&J DTS! I'm looking forward to seek Gods heart for this world together and live it out.
No information available
Hi, I'm Bart, married with Marieke. We have 3 kids. It's my desire to make Jesus known in the Netherlands and Europe. That's why I'm overseeing the evangelism center at Heidebeek. Mainly I work with an event called 'the God Story'.
Henk van Huizen
Hello, I am Henk married with Rachel.
I'm all about: Exploring Experiencing Expanding the Kingdom of God's mercy and grace on Earth.
Family man, avid sports fan, who has been with YWAM since 2003. Working with GO Teams.
Rachel van Huizen
Hello, I am Rachel married with Henk.
Franc Tollenaar
I am Franc Tollenaar, 33 Years old and happily married to Jacolien. The time before YWAM Heidebeek I studied theology in Leuven (Belgium) and Amsterdam. I have a great passion for Jesus, He is the one who inspires me. I looking forward to the Mini DTS 2017. God is faithful and it´s His heart to reveil Himself to His children!
Mirjam Gosseling
My name is Mirjam Gosseling. Im married to Bernd Jan and since august 2011 we have a son, Levi. Since 2004 i work with DTS's. I worked with several DTS's and led different outreaches, to Poland, Niger, The Middle East and visit many more countries. Since 2008 I m coordinator of the different DTS's we run at Heidebeek.
No information available
My name is Mayke Shaw. I'm working within YWAM since 2005. Married to Carl Shaw and mother of Ruben and Femke. I'm involved with the Mercy and Justice DTS. Challenging people for missions is what I like.
Andreas Kok
No information available
Hi, my name is Anne, 24 years old. Last year I did my own DTS, it was an amazing time. I could see that God was working in and trough me. I'll be happy to be part of passing this great experience onto others as well coming year. DTS changes your life, so don't miss it! ;)
Eline Bakker
Hey, my name is Eline and I'm 21 years old. Last year I did the classic DTS. I had an awesome time. It's great to see God working and to live in dependence on Him. My desire is that more people will discover what it means to have a personal relationship with God. I'm really looking forward to the coming DTS!
Hello my name is Geerte, I'm 21 years old. I did my DTS September 2015, it was life changing and amazing. Now I have the privilage to be a part of the DTS staff team. It's so wonderful to see God working! I'm so excited for the next DTS to start!


text:
Detail Information
- The paintfill method as a tool for analyzing the three-dimensional structure of the inner earAmy E Kiernan
Department of Ophthalmology and Center for Aging and Development, Box 314, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
Brain Res 1091:270-6. 2006..The paintfill method can be used to quickly assess inner ear morphology and can help identify defects that may cause or contribute to deafness and/or vestibular dysfunction...
- Notch signaling during cell fate determination in the inner earAmy E Kiernan
Department of Ophthalmology, University of Rochester, Rochester, NY 14642, United States
Semin Cell Dev Biol 24:470-9. 2013....


text:
This is the records summary for Jan. 5.
Area law officers arrest 28 for drunken driving in December
WILLMAR — Officers from west central Minnesota law enforcement agencies arrested 28 drivers for driving while impaired during the month of December.
The arrests were made during a Drive Sober or Get Pulled Over DWI campaign that ran statewide for the month to combat drunk driving. The Minnesota Department of Public Safety Office of Traffic Safety coordinated the campaign.
"DWI patrols are effective to reducing drunk driving activity, but it is clear that the issue remains a real problem that puts our roads in danger," says Kandiyohi County Sheriff Dan Hartog. "To make progress and limit the tragedies that drunk driving causes, we need to take the simple, preventable steps, and step one is to always plan ahead for a sober ride."
The local agencies participating in the campaign included the Kandiyohi and Swift county sheriff's offices along with the police departments from Willmar, Atwater and Benson.
According to statewide statistics released Thursday by the DPS, preliminary numbers for 2012 show that 26,628 motorists were arrested for driving while impaired. There were 29,918 DWI arrests in 2011. The preliminary DWI arrest count will grow as alcohol-concentration data is finalized.
The local law agencies remind that the consequences of a drunken driving conviction include the possibility of losing your license for a year, thousands in costs and possible jail time. Repeat offenders, as well as first-time offenders arrested at 0.16 and above alcohol-concentration level, must use ignition interlock in order to regain legal driving privileges, or face at least one year without a driver's license. Offenders with three or more offenses are required to use interlock for three to six years, or they will never regain driving privileges.
New storm sirens added in Meeker County
LITCHFIELD — Three new emergency outdoor storm warning sirens are being added to Meeker County's existing system of 20 outdoor sirens already operating in the county.
Sheriff Jeff Norlin announced Friday that the new sirens are being installed at Clear Lake County Park, along the north side of Big Swan Lake on County Road 21 and on the north side of Lake Francis in Kingston Township.
All of Meeker County's storm sirens can remotely be activated from the county dispatch center as the emergency warrants. The outdoor warning siren systems are part of the early warning system for persons who may be outdoors prior to a severe weather event.
Clara City man to hospital after Highway 23 crash
NEW LONDON — An 88-year-old Clara City man was taken by ambulance to Rice Memorial Hospital in Willmar for treatment of non-life threatening injuries sustained in a two-vehicle crash around 6 p.m. Wednesday north of New London.
According to the State Patrol, Robert Harold Brix was driving a Dodge Journey that struck from behind a Subaru driven by Quinn Jeffrey Rosendahl, 31, of New London, while both vehicles were southbound on Highway 23. Rosendahl had slowed the vehicle to make a left turn off the highway near 212th Avenue Northeast.
WILLMAR — A 36-year-old man was arrested shortly before 1 a.m. Friday on suspicion of second-degree driving while under the influence. The arrest took place at the intersection of 60th Street and 15th Avenue Southeast.
WILLMAR — Two motor vehicle crashes involving five vehicles were reported late Friday morning at the intersection of Fifth Street Southeast and 19th Avenue in Willmar.
In the first crash, reported at 11:21 a.m. Friday, a vehicle traveling on 19th Avenue allegedly ran a red light and hit two other vehicles. Two people involved in the crash were taken to Rice Hospital by ambulance.
In another crash reported at 11:38 a.m., a vehicle stopped in the road because traffic was blocked because of the earlier crash was rear-ended by a second vehicle. There was light damage reported to both vehicles.
Names of drivers or those who were injured were not available from law enforcement on Friday.
District Court
Kandiyohi County
- Justin Paul Nelson, 25, of Lake Lillian, pleaded guilty Thursday to a felony charge of fifth-degree drug possession for methamphetamine found in a motel room in Willmar.
As part of a plea agreement, charges for receiving stolen property, possession of a weapon by a person convicted of a violent crime and for storing methamphetamine paraphernalia in the presence of a child or vulnerable adult will be dismissed. He will be sentenced Feb. 19.
Nelson and a juvenile, Steven Anthony Aguilar-Mota, 17, of St. Paul, are charged in the case. Aguilar-Mota pleaded guilty to a felony receiving stolen property charge and was sentenced, under a change of venue to Ramsey County, to 180 days of probation, 32 hours of community work service and an intensive supervision program.
Felony charges against 16-and 17-year-old juveniles are public record.
The charges were filed after Nov. 15, when CEEVI Drug Task Force agents were conducting a follow-up investigation in the parking lot of the Lakeview Inn, along Business 71 North in Willmar. They noticed a vehicle with loud music and recognized the driver of the vehicle as Johnny Juan Molina, 28, of Willmar. Molina was taken into custody for driving on a revoked license and was searched, revealing a pipe with methamphetamine residue.
In an effort to identify Aguilar-Mota, whom agents saw walk up to Molina's vehicle, the agents knocked on a nearby motel room door. Nelson opened the door and was arrested on a Department of Corrections warrant.
Based on the drug paraphernalia, digital scale with drug residue and ammunition in plain sight in the hotel room, the agents were granted a search warrant for the room. They located a stolen .357-caliber Magnum revolver under the bed, a small amount of methamphetamine and marijuana and $2,080 in cash.
The gun was traced as a weapon stolen in 2007 in Swift County. Nelson had a prior conviction for second-degree drug sale in 2010 in Kandiyohi County.
- Cody Scott Johnson, 20, of Willmar, pleaded guilty Friday to a misdemeanor charge of domestic assault for hitting a 2-year-old child in October.
As part of a plea agreement, a third-degree assault charge will be dismissed. Johnson will be sentenced Feb. 7.
The charges were filed after Oct. 25, when Willmar Police officers were called to a home along Eighth Avenue Southeast on an assault. A woman there reported that Johnson had hit her son.
Johnson told the officer that said he and the woman had talked about the boy learning not to swear and that the child called someone a swear word. Johnson said he told the boy not to swear and that he flicked the boy's lip as punishment.
The woman said Johnson hit the child in the face with his right hand and showed the officer that the child's upper lip was bleeding. She said the child interrupted their conversation and that Johnson got upset and hit the child.
- Jason Richard Meyer, 30, of Willmar, made his first appearance Friday on felony charges of fifth-degree drug possession and for storing meth paraphernalia in the presence of a child.
Unconditional bail was set at $40,000. His next appearance is Jan. 14.
Meyer also faces a gross misdemeanor charge for possessing a pistol or assault weapon after being convicted of a felony.
According to the complaint, Kandiyohi County Sheriff's deputies went to a New London residence, where Meyer also lived, on Nov. 28 looking for a man for whom they had an arrest warrant. The deputies didn't find the man wanted on the warrant and were allowed to search the residence, finding several guns located throughout the house.
Later, deputies were informed that Meyer is a convicted felon, convicted of a first-degree controlled substance crime in 2002, and therefore not allowed to have guns. A search warrant was drafted and the search revealed nine guns, shotguns, rifles and handguns, along with ammunition and gun scopes, in the home.
During the gun search, deputies found evidence of drug use and drafted a second search warrant. That search revealed drug paraphernalia that tested positive for methamphetamine.
The investigation also revealed that a 12-year-old child lives at the home.


text:
Dose-escalation, Safety, Pharmacokinetics Study of AVE8062 Combined With Bevacizumab in Patients With Advanced Solid Tumors
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: August 31, 2010
Last updated: December 2, 2014
Last verified: December 2014
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
Primary Objective:
- To determine the maximum administered dose (MAD) and the maximum tolerated dose (MTD) of ombrabulin in combination with best tolerated dose of bevacizumab based on the incidence of related Dose Limiting Toxicities (DLTs).
Secondary Objectives:
- To assess the overall safety profile of the combination
- To characterize the pharmacokinetic (PK) profile of both ombrabulin and bevacizumab when given in combination
- To evaluate preliminary evidence of anti-tumor activity
- To assess the pharmacodynamic effect using (Dynamic Contrast Enhanced Ultra-Sound) DCE-US, measuring biomarkers
|Neoplasms, Malignant
|Drug: Ombrabulin (AVE8062) Drug: bevacizumab
|Phase 1
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|An Open-label, Non-randomized, Dose Escalation, Safety and Pharmacokinetic Phase I Study of Ombrabulin (AVE8062) in Combination With Bevacizumab Administered by Intravenous Infusion Every 3 Weeks in Patients With Advanced Solid Tumors.
Resource links provided by NLM:
Drug Information available for: BevacizumabU.S. FDA Resources
Further study details as provided by Sanofi:
Primary Outcome Measures:
- Incidence of Dose Limiting Toxicities (DLTs) that will define the MTD [ Time Frame: 3 weeks ]
Secondary Outcome Measures:
- Overall safety profile of the combination [ Time Frame: up to a maximum follow-up of 1 year ]
- Pharmacokinetic parameters of ombrabulin [ Time Frame: 6 weeks ]
- Pharmacokinetic parameters of bevacizumab [ Time Frame: 6 weeks ]
- Preliminary evidence of antitumor activity according to Response Evaluation Criteria in Solid Tumors (RECIST 1.1) [ Time Frame: up to a maximum follow-up of 1 year ]
- Pharmacodynamic effect (biomarkers) [ Time Frame: cycle 1 ]
|Study Start Date:
|September 2010
|Study Completion Date:
|October 2014
|Primary Completion Date:
|October 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: AVE8062/ bevacizumab
The combination of ombrabulin and bevacizumab will be administered every 3 weeks according to the following schedule: One day 1, ombrabulin will be administered as a 30 minutes intravenous (i.v) infusion. Bevacizumab will be administered as a 30-90 minutes i.v. infusion 24 hours after the end of ombrabulin infusion on day 2.
Drug: Ombrabulin (AVE8062)
Drug: bevacizumab
Pharmaceutical form:Solution for infusion
Route of administration: Intravenous
Pharmaceutical form:Solution for infusion
Route of administration: Intravenous
Detailed Description:
The duration of the study for each patient will include an up to 28-day screening phase, 21-day study treatment cycles, an end of treatment visit with a follow-up period. Each patient will participate in only one dose group and will receive AVE8062 with bevacizumab every 3 weeks until disease progression or unacceptable toxicities, withdrawal of consent or Investigator's decision.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion criteria:
- Histologically or cytologically proven solid malignant tumor at the first diagnosis with the exception of squamous non small cell lung cancer (NSCLC).
- Advanced neoplastic disease (i.e. metastatic or locally unresectable advanced disease)
- Presence of one measurable lesion at baseline in the MTD expanded cohort
Exclusion criteria:
- ECOG (Eastern cooperativeOncology Group) performance status > 1
- Concurrent treatment with any other anticancer therapy
- Pericardial effusion requiring intervention (drainage)
- History of brain metastasis, spinal cord compression or carcinomatous meningitis or new evidence of brain metastasis on screening Computed tomography (CT) or Magnetic resonance imaging (MRI) scan
- Diagnosis of squamous Non Squamous Cell Lung Cancer (NSCLC) or with mixed cell type with predominant squamocellular histology
- Hormone sensitive prostate cancer
- Abdominal Radiotherapy
- Major surgery within the last month of study enrollment or surgical wound not fully healed before study enrollment
- High cumulative doses of anthracycline
- Inadequate organ function
- Inadequate hematology function or poor bone marrow reserve
- Any of the following within 6 months prior to study enrollment: peptic ulcer disease, erosive oesophagitis or gastritis, infectious or inflammatory bowel disease and diverticulitis
- Any history or underlying cardiac condition that may increase the risks associated with the study participation or administration of the investigational products, or that may interfere with the interpretation of the results.
The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01193595
Please refer to this study by its ClinicalTrials.gov identifier: NCT01193595
|Investigational Site Number 250001
|Villejuif Cedex, France, 94805
|Investigational Site Number 380002
|Milano, Italy, 20132
|Investigational Site Number 380001
|Milano, Italy, 20133
|United Kingdom
|Investigational Site Number 826001
|Sutton, United Kingdom, SM2 5PT
Sponsors and Collaborators
|Study Director:
|Clinical Sciences & Operations
More Information
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT01193595 History of Changes
|Other Study ID Numbers:
2009-017797-20 ( EudraCT Number )
|Study First Received:
|August 31, 2010
|Last Updated:
|December 2, 2014
Additional relevant MeSH terms:
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Antineoplastic Agents
ClinicalTrials.gov processed this record on September 21, 2017


text:
Tattler Reusable Jar Lids
Inexpensive food storage
For years I've loved GlassLock Containers [reviewed on Cool Tools] because they seal water-tight. I also love that they are glass (no chemical leaching, microwaveable).
But they are relatively expensive — $45 for 9 containers. When I pack some lunches, my wife doesn't have enough for leftovers. Since they come in different sizes, I'm always looking for the right lid.
The Tattler Reusable lids work better for my lunches. $7 for the lids and $20 for a dozen widemouth pint jars. Now I've got a dozen smallish water-tight containers with interchangeable lids. Widemouth pint jars are freezeable so I can freeze if I need to. If I was motivated, I could also these for canning or pressure canning. (Mmm, Chili.) Since widemouth jars are pretty pervasive, it's easy to find smaller or bigger jars.02/18/14
(I use widemouth canning jars to store nuts and seeds for snacking. Plastic lids are more convenient than 2-piece canning jar lids for this purpose. - Mark — editors)
Tattler Reusable Wide Mouth Canning Lids & Rubber Rings 12 for $7


text:
A TWITTER rumour has put Menstrie residents in a frenzy after it was claimed football hero David Beckham was spotted in the village earlier today.
One user of the social networking site, who goes by the name of Trebor, posted, "Just seen David Beckham" - which was soon met with a flurry of disbelieving comments from fellow Tweeters.
He claimed former Manchester United, Real Madrid and England star Beckham was at the Diageo plant and there was "security everywhere".


text:
Your Javascript is turned off. You need Javascript to be turned on to view this site.
Please update your flash player...
Game Change
Duration :
Summary: With John McCain trailing in the polls during the 2008 U.S. presidential election, strategist Steve Schmidt knew he needed a "game changer" to turn the tide. With Sarah Palin, he thought he had found that person. From director Jay Roach and writer Danny Strong--the team behind HBO Films' 'Recount'--comes this searing, behind-the-scenes look at McCain's ill-fated campaign. Told primarily through Schmidt's eyes, the film pulls back the curtain on the McCain team and their clash over politics and principles as Schmidt championed Palin as McCain's running mate only to later regret it as pressures on the Alaska Governor brought the campaign perilously close to irrelevance. Nominated for 12 Emmy(R) Awards, including Outstanding Miniseries or Movie. Julianne Moore, Woody Harrelson and Ed Harris star. Directed by Jay Roach; written by Danny Strong, based on the book by Mark Halperin and John Heilemann. (TVMA) (AC,AL)
PRODUCER : Amy Sayres,Tom Hanks,Gary Goetzman,Jay Roach
CAST : Julianne Moore,Woody Harrelson,Ed Harris
WRITER : Danny Strong,Mark Halperin,John Heilemann
DIRECTOR : Jay Roach
Genre : History
Order Now
On-demand Schedule
HBO Go Schedule
©2017 Home Box Office, Inc. All Rights Reserved. This website may contain mature content.


text:
NEWPORT'S Liz Johnson tonight took bronze in the SB6 100m breaststroke.
Johnson, who won gold in Beijing four years ago, set a new Paralympic record of 1:41.09 in qualifying for tonight's final. She then saw GB team-mate Charlotte Henshaw go under it in the second heat with a time of 1:39.64.
In the final 14-year-old Ukrainian Viktoriia Savtsova claimed the record herself with a time of 1:39.19, Henshaw (1:39.16) taking the silver.


text:
Willoughby police are asking the public to help identify the suspects in a reported theft from earlier this year.
The crime allegedly occurred at the end of March on Airport Parkway.
There is no description available of the suspect or suspects, but the vehicle used was a red Ford pickup truck with an extended cab and a red cover over the truck bed, police said.
The truck also has chrome step rails on each side of the vehicle, police said.
Anyone with information about the truck or anyone who may know the owner is asked to contact Detective George Lessick with the Willoughby Police Department at 440-953-4210.


text: Show Hide image Politics 5 June 2012 Norsk Hydro to close plant in Australia Weak environment in the aluminium industry. Sign up for our weekly email * The Norwegian aluminium producer Norsk Hydro announced today that it will close the Kurri Kurri plant, located near Newcastle in New South Wales, Australia. The decision comes after consultation with the workforce and the unions. Norsk Hydro has been hit by the weak macroeconomic environment, with low metal prices, an uncertain market outlook and overcapacity in the aluminium industry, as well as the strength of the Australian dollar. The Kurri Kurri plant, acquired in 2002, has three production lines with a total annual production capacity of 180,000 metric tons. One potline was curtailed in February. The closure of the remaining two potlines will begin shortly and is likely to take up to three months. More than 300 people are expected to be made redundant. Hydro expects an expense of about NOK200m related to redundancies and an impairment charge of about NOK1.2bn in the second-quarter results. The company employs 23,000 people in more than 40 countries. Subscribe from just £1 per issue More


text:
Howdy, Stranger!
It looks like you're new here. If you want to get involved, click one of these buttons!
Project Cars--You Get to Vote on "Hold 'em or Fold 'em"
I'd have thought the biggest stock engine in an Elite would be a 351 or maybe a 400. Was a 460 used on that midsized (relatively) platform?
The dashboard of that Comet is pretty unpleasant, I never liked the rear end of those either.
I'd have thought the biggest stock engine in an Elite would be a 351 or maybe a 400. Was a 460 used on that midsized (relatively) platform?
Yep, even in '76 you could get a 460 as an option on the Elite. The 351 was actually the standard engine! And the 400 was a mid-range option.
At some point, I think even in the lesser Torino models, a 351 was made standard, because the 6-cyl and even the 302 engines just weren't up to the task. That must have made them a hard sell to fuel conscious buyers.
I think GM and Chrysler started phasing the bigger engines out of their cars after 1975. For instance, in the 1976 Chevelle/Malibu and Monte Carlo brochures, they list a 175 hp 400 V-8 as the top engine. By that time, I guess the 454 was reserved for Impala/Caprice duty?
I know you could still get a 455 in a LeMans or Grand Prix in '76, and they actually seem somewhat common in the Grand Prix.
For '77, the biggest engine you could get in a Malibu/Monte was a 350, ditto the Century/Regal. The Cutlass could be had with a 403, and the LeMans/Grand Prix could be ordered with a Pontiac 400 (Olds 403 in CA). That same year, Ford quit offering the 460 in midsized cars, but still offered the 400 in the LTD-II/Cougar/T-bird.
I've heard that Chrysler still offered the 440 in midsized cars right up through 1978, but I think in those last couple years, it might have been a copcar-only engine.
"At some point, I think even in the lesser Torino models, a 351 was made standard, because the 6-cyl and even the 302 engines just weren't up to the task. That must have made them a hard sell to fuel conscious buyers. "
According to the ad, those folks would get the 429, right?
I like that Ford van. I think that's the first long body I've seen of that generation in well over a decade. Far and away, the vast majority of the survivors are short bodies.
Of course, I have my own van that I need to put right before I'd seriously consider anything else, but it's still fun to look. :blush:2014 Audi Q7 TDI, 2008 and 2013 Subaru Forester(s), 1969 Chevrolet C20 Pickup, 1969 Ford Econoline 100, 1976 Ford F250 Pickup
I went back to the seller's CL ad and it looks like it's been edited to now state: "I have a black 75 Ford elite same line as torino but not to many of these made ... getts not to bad mpg" No more mention of engine size.
I don't remember Ford offering the 429 in passenger cars after 1974.
That's the longer Econoline Supervan which Ford started making in '65. I think they made a camper version of this too.
I didn't realize the called it "Econoline" prior to the generation change in '69. My '69 has a nameplate on the back that says "Supervan," and it cracks people up when they see it.
Of course, the whole van cracks them up initially, so perhaps they're already in a jovial mood when they get to looking at that detail. :blush:2014 Audi Q7 TDI, 2008 and 2013 Subaru Forester(s), 1969 Chevrolet C20 Pickup, 1969 Ford Econoline 100, 1976 Ford F250 Pickup
Funny thing is that I can always do a quick CL search of rust belt cities (Detroit, Columbus, Pittsburgh, NY/NJ metro) and find running, licensed 70s LTDs for sale. Although sometimes the seller's ad seems like a joke or one big typo. You know it's going to be fun when something is listed as "almost immaculate"
Definitely too many zeros in that one! I wonder what class he was attending... remedial math?2014 Audi Q7 TDI, 2008 and 2013 Subaru Forester(s), 1969 Chevrolet C20 Pickup, 1969 Ford Econoline 100, 1976 Ford F250 Pickup
boomchek Vancouver, BC, CanadaPosts: 5,314Definitely too many zeros in that one!
Ha, I peaked at the ad and though it was $5k as well until you mentioned it. Funny with the line about no low ballers too.
2007 BMW 328i Sports Pkg
Yeah, I didn't catch it in the ad title, but then he listed the same amount in the body of the ad as well (even included the comma in the right place), and then I just started laughing. If he really wants that price, he'll be keeping the old girl for quite some time to come. :P2014 Audi Q7 TDI, 2008 and 2013 Subaru Forester(s), 1969 Chevrolet C20 Pickup, 1969 Ford Econoline 100, 1976 Ford F250 Pickup
For the most part, I never really cared for those big '73-78 LTDs. I think part of the problem was that they dropped the true hardtops after just a couple years, and just went with that "pillared hardtop" look on the sedans. But then, as a kid, I was sort of taught to hate Fords, because my Dad hated them, and so did my Granddad (on my Mom's side...my other Granddad cherished the things!). So, I might have been biased, just a bit. :P
I always liked the Marquis/Grand Marquis equivalents, though. I appreciated the fact that the coupe kept the hardtop look all the way up through the end, although I'm sure at some point they started charging you extra for roll down windows in back, and towards the end they might have made them all stationary.
It's been ages since I've seen either, outside of a car show, but it seemed like the big Mercurys hung around longer than the big Fords did. Maybe they were bought by people with a bit more money, who took better care of them? Seems like dove gray or silver was a common color for the Marquis.
There's a '76 or so LTD that shows up regularly at one of the car shows I attend, in Magungie PA. It's red, and quite luxurious looking.
The full-size Fords of the mid-70s were not as bad for rusting as the '71-'73 models, which rusted almost instantly. I don't know what changes they made later on to protect them, but the later ones were better in that respect.
The big Fords were just that - big. To me they seemed bigger than the Chevys of the era, though that may not be factually accurate. Being Fords of that time, though, they came with Novocaine steering and a super-soft suspension too, so they were not the easiest things to drive. But I liked them anyway because of their interiors and the styling.
The Comet dashboard was exactly like the one in our '74 Maverick right down to the color. I always hated the "cane" parking brake on those - it seemed so primitive. The only difference for '75 is that the spokes of the steering wheel dipped downward at either end, whereas the '74 had 2 spokes that ran straight across. I'm sure the Comet was just as unsatisfying to drive as our Maverick was. I do remember the salesman at the Lincoln-Mercury dealer telling us when we were in buying mode that the Comet used a heavier gauge of steel than the Maverick in the body. That's gotta be sales talk, right?
There WAS a difference that I detected once we bought our Meverick. Right behind the front bumper, the front fenders stopped at about bumper height and there was a small metal panel that filled the rest of the space downward. On the Maverick that flexed quite easily with mild pressure, but the Comets on the lot didn't do that. Of course, given our Maverick began rusting out the minute we took it home, maybe it was already weakened by corrosion.
2017 Cadillac ATS Performance Premium 3.6, 1968 Oldsmobile Cutlass S Holiday Coupe
The big Fords were just that - big. To me they seemed bigger than the Chevys of the era, though that may not be factually accurate.
IIRC, the Fords rode a 121" wb and the Chevies a 121.5", so they were close enough there. Overall length probably varied a bit from year to year with bumpers and such, but I think the '76 Chevy topped out at around 221". I have an old Consumer Guide used car book that covers 1977-85 (except for cars that were in their last year in '77), and it lists the LTD at "only" 219 inches. That doesn't seem right to me, though.
The Fords had more of a straight-edged, linear look to them, and seemed a bit lower overall. So maybe that made them look longer?
Something about the rear of the Chevies seemed a bit shorter too, at least from 1974-76. Instead of taking on a 5 mph bumper that added about 5 or 6 inches to the overall length, it looks like they shortened the rear deck a bit, and then stuck on the 5 mph bumper, but still maintained roughly the same overall length.
lemko Philadelphia, PAPosts: 15,294My Dad had a 1972 Ford LTD Country Squire and it was a dog! That car more than anything made me disdain most anything with the blue oval. When my Grand Marquis acts up, memories of that LTD come flooding back.
The only story I can relate to those big Fords was a '73 LTD hardtop coupe that the mother of one of my friends had when he was a little kid. It refused to start on a fairly regular basis, and tended to stall out. He and his brothers called it "Mommy's Hunk O'Junk"
It got replaced by a Volare wagon, a 1977 I think, which was actually a pretty good car but it got hit and totaled by a delivery truck.
I only have vague memories of my mother's gargantuan T-Bird, but I do remember it in the driveway with the hood up. It would have been under 10 years old, apparently developed starting and cold running issues from an early age. - emissions junk related, IIRC. And if I hint at it, I can get the story of when the cruise control stuck. It was sold to a friend of my dad's, and I know it was off the road by 1985.
toomanyfumes S.E. Wisconsin Posts: 1,003I had a mid-70's Comet for a short period of time. My Brother-in law overheated it and blew out a freeze plug on the straight six block, I fixed it and sold it for a decent profit. I remember the cheesy cane parking brake handle, and the panel under the rear bumper, the side welds rusted, and it would just hang, they all seemed to do that.2012 Mustang Premium, 2013 Lincoln MKX Elite, 2007 Mitsubishi Outlander.
stkntraffic Posts: 172When I was a kid my Dad had a '76 Grand Marquis 4-door, in the most awful shade of powder-blue. I don't think he kept it that long. It was a tank.
Well, if you want to re-live your childhood, here's a Powder Blue '78 for sale.
Y'know, for $1900, this one looks pretty nice. Unless it's hiding something.
I actually like those pale blues and greens from the 70's, but sometimes it seems like just the slightest variance in hue can make a world of difference. For instance, there's a powder blue that GM used in '75, that seemed extra common on Buicks, that I really love. But on that '78 Grand Marquis, I just don't like its hue quite as much.
On a Grand Marquis, I think a deeper, metallic blue would probably work better with its ritzy, upscale style.
There's been a powder blue 2-door '78 (I think) Marquis for sale up here for at least a couple of years. I think the price is something ridiculous, like $8K or thereabouts.The 2-door version is kind of odd-looking. The relatively small greenhouse compared to the huge body makes it look like a really overweight house cat.
2017 Cadillac ATS Performance Premium 3.6, 1968 Oldsmobile Cutlass S Holiday Coupe
I can buy a '53 GMC 3/4 ton pickup for $500. It is 100% all there, and it hasn't run in 30 years. It's dirty, it's dented, there are parts piled in the bed. No broken glass however. It's really a mess.
Before you say "you're crazy", these early 50s Pickups are doing some serious escalation in value the last two years.
Upside: Classic styling, big GMC 260 (??) engine, 4-speed.
Downside: 3/4 ton, needs everything done to it. May or may not run. Big question mark.
MODERATOR --Need help with anything? Click on my name!
Not a speck of rust anywhere! But some of the fenders have decent dents.
MODERATOR --Need help with anything? Click on my name!
tjc78 JerseyPosts: 6,359What would you do to it? Full resto or just do enough to get it running/driving and flip for a small profit.
2015 Buick Enclave / 2017 Hyundai Elantra
Sounds like a great project, if that's your kind of thing. Friend restored a '40, let me drive it, scared me half to death until I figured out the steering only had an incidental impact on the truck's direction, and that the springs were strictly decorative!
Just getting cleaned up and running would net you quite a bit, I'd think. No body work or interior work, just the mechanicals. ("Just" being wildly inappropriate, I know).
Edit - looks like tic and I have the same idea!
qbrozen Posts: 21,964I wouldn't say you are crazy. Its $500 for 50s metal. Have you every watched Counting Cars? He pays crazy money for vehicles in worse shape, IMHO.
I'd buy it. I've been wanting a pickup rat rod for a while now.
'17 F150 Crew 2.7; '67 Coronet R/T; '14 Town&Country Limited; '09 LR2 HSE. 44-car history and counting!
Probably worth that in scrap. Worst case scenario, it becomes too much of a project, and you part it out for a profit.
I took that gamble back in 1997 on a truck that had sat for 23 years (paid $500). It has paid off in spades for me! The big difference is that the interior was spotless (under that 1/2" of dust), so everything I needed to do was either exterior or mechanical, and it turned out that it needed very little of either.
S-C-O-R-E for me, but still a gamble.2014 Audi Q7 TDI, 2008 and 2013 Subaru Forester(s), 1969 Chevrolet C20 Pickup, 1969 Ford Econoline 100, 1976 Ford F250 Pickup
I'd just get it safe and running tcj, and use it for hauling stuff to the dump, or garden work, etc. Of course, "safe and running" could be a big deal in itself!
But I've found that once an old heap actually runs, and can be driven around the block, however badly, that this greatly improves its value to a "dreamer".
50s pickups, to their credit, are generally much easier to restore than equivalent era cars.
MODERATOR --Need help with anything? Click on my name!


text:
so I am starting to buy cloth diapers that way in a few months I will be ready to switch my son to them, I am however confused with some of them. I love the ones that have the snaps/buttons but I have no clue what they are called. also what are inserts? when the child goes to the bathroom do you just change the inserts or do you change the whole diaper, and what type of detergent do you use for them? TIA and sorry for all the questions :)
Lots of diapers have snaps, it's usually either snaps or velcro. How you change the diaper depends on the diaper. An AIO is an all in one and you change them sort of like a disposable, when the baby goes to the bathroom you take off the whole diaper and put it in a wet pail (shake poop into the toilet if the baby pooped lol). Some diapers have inserts (like gDiapers) and you can re-use the cover as long as it isn't wet/soiled, but if it's wet or soiled it also needs to be washed. Prefolds you fold the diaper and put it on the baby and put a cover over it, some you'll need something to hold the diaper together (like Snappis) before putting the cover on. I use free and clear detergents and you use a little less detergent than you would for clothes to avoid soap build up, and bleach generally isn't good for diapers but I guess is okay occasionally for some cloth diapers.
I really want to cloth diaper but i just have NO IDEA how to go about it, my DD is almost 9 months and using less diapers now anyway..the only reason i havent is the cost i'm afraid i'll spend 100 and hate them (altho 100 dollars isn't terrible when i think about disposable diapers for the next year plus)
ive only cloth diaper my little girl. you can pm me any questions and ill help but to answer your questions here, snaps are the closure or how you make a one sized(os) diaper smaller. inserts go inside pocket diapers or flips (different kinds of diapers) this is the absorbent part. :) i use tide for my dipes. other people like other things


text:
user functions
Current Ithaca College community members may contribute stories and comments as well as view additional topics by logging in.
related links
Computer Training Workshops Week of Feb. 12th
Contributed by Beth Rugg on 02/06/07
The Spring 2007 workshop schedule is up and running! The ITS Workshop Program can help you learn new computer skills or brush up on programs you already know.
© Copyright Ithaca College. All rights reserved; unauthorized use prohibited. All material on this server is produced by our community but, except for designated pages, is neither approved nor verified by Ithaca College.


text:
Georgina Heffernan: The vintage influence is evident in most of your creations - why are you inspired by the styles of yesteryear?
Ruffled Ruby: It is the attention to detail and amazing craftsmanship that went into the creations that has inspired Ruffled Ruby. The quality of design, level of detail and the time spent creating is admirable. Quality can often be jeopardised in the process of modern day mass production so we feel that our designs pay homage to the eminence and timeless quality of vintage accessories and their designers.
Where do you get the ideas for your creations?
We brainstorm ideas together and very often we are inspired by the materials we are working with from intricate beaded lace to a whimsical vintage brooch. Also from clients, discussing their requirements, hearing about their beautiful dress and the style they wish to achieve will generate a vision for the design.
Are there any celebrities that inspire your style?
Imelda May is an inspirational Irish woman, she wears the rockabilly fashion with style and sophistication. Alexa Chung has fantastic style, she mixes a lot of vintage with modern high street fashion which shows how versatile vintage pieces can be. We've also been drawn in by the Mad Men ladies, Christine Hendricks and January Jones look absolutely amazing on screen.
Is it difficult to compete with the highstreet, in terms of price and quality?
Budget is hugely important when it comes to wedding planning and we offer a range of bouquets, buttonholes and corsages to suit. With a Ruffled Ruby piece you get attention to detail and quality bespoke design.
Where do you see your company going in the future?
We want to build our client base, advance and refine our design process and work with our clients needs to adapt and diversify our products. This includes constantly sourcing and experimenting with new quality materials for our original designs. We are currently working on expanding the range to include a "something blue" range. We are also working on a predesigned range of wedding accessories which will be available to purchase directly from our website.
And lastly, where is Ruffled Ruby available to buy?
You can visit us on our website www.ruffledruby.com or find us on facebook/ruffledrubyweddings where you can contact us to discuss ideas or arrange consultations. We are also delighted to be part of The Design Atelier on Sarsfield Street in Limerick. Two amazing designers Aisling Maher Milliner and Marion Murphy Cooney have come together to open a design center. Ruffled Ruby designs will be showcased and available in store from Saturday July 14th following the official launch.