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Harry Kewell and Brett Emerton worth their weight in gold.
THEY are soccer's $20 million men, and tonight, when Melbourne Victory takes on Sydney FC, they will come face to face at a packed Etihad Stadium for the most eagerly awaited A-League kick-off of them all.
Harry Kewell and Brett Emerton would not fetch anything like that sum on the transfer market, nor will their earnings reach that level now they are back playing in Australia.
But, according to advertising guru Harold Mitchell, that $20 million figure is how much the two high-profile Socceroos could contribute in added value to the game in this country.
Mitchell, a man with a shrewd knowledge of the value of sponsorship, advertising and media rights in sport, believes soccer has a historic opportunity over the next few years to capitalise on the value of the best known of its returning heroes.
''These two could add $20 million to the overall revenues of the game. You have seen already how much interest they have generated in the lead-up to the season. Advertisers, sponsors and those involved in sporting rights will see the impact that they have,'' says Mitchell. ''The 2011-12 season will be seen as pivotal - the start of a more mature competition. A competition still learning and with room for improvement, but with a very bright future.
''Like all entertainment forms, football needs its stars. The injection of Harry Kewell and Brett Emerton into the two biggest franchises is timely and the rock on which the sport can now build a sustainable future.''
There are parallels between the two Sydneysiders. Both travelled to trial together with Leeds United as teenagers but Emerton - unlike Kewell, who had an English background - could not get the visa needed to take up an offer with the Yorkshire club.
While his countryman was making his mark as a youngster in the Premiership, Emerton became a star in the old National Soccer League with Sydney Olympic. He eventually captained his country at the 2000 Olympics in Sydney, a tournament Kewell missed through injury.
Emerton completed his footballing education with Dutch champion Feyenoord, with whom he won the UEFA Cup before finally joining Kewell in the Premiership, where he spent eight years with Blackburn Rovers before returning home.
Kewell is the more naturally skilful and talented of the two, but there is no doubt Emerton (while a skilful player himself) is the better athlete. He is known affectionately by teammates around the Socceroo camp as a ''beast'' for his physical fitness and his ability to continue grinding away at a beep test when everyone else has called it quits.
Kewell's biggest achievements came early in his career, as a flying winger with a swashbuckling young Leeds side.
His big-money move to Liverpool came as Leeds imploded and was not without controversy. Injuries cruelled his time at Anfield, and although he picked up a Champions League and FA Cup winner's medal, it is fair to say he never fulfilled his potential in the famous red.
Emerton's EPL career was something of a contrast. Playing for a battling Blackburn, it was more often than not a struggle to stay in the elite level occasionally leavened by the thrill of a good cup run.
While the pair have plenty to offer off field, their primary duty will be to deliver on the pitch.
Certainly their teammates say they are already having a major impact.
''For 'Emo' to leave the Premier League and to come straight to Sydney FC shows the ambition, what we are about and where we want to go as a club when we can attract current EPL players back to Australia and to Sydney, '' says Sydney skipper Terry McFlynn. ''From the first day he came in his attitude has been fantastic.''
Sydney coach Vitezslav Lavicka echoed McFlynn.
''His impact has been similar to Harry Kewell for Melbourne Victory. Their return is a great message for Australian football.''
Grant Brebner, Victory's veteran midfielder, came through at Old Trafford as a junior when David Beckham, Paul Scholes, Nicky Butt and the Neville brothers Phil and Gary were just ahead of him. He says Kewell's effect has been ''massive''.
''He's given us a huge lift coming into the season,'' Brebner says. ''He's played and trained at the highest level. It's the little things that he does that you notice, that people wouldn't probably notice. His professionalism, the way he conducts himself at training, the passes that he sees. He's obviously a level or three above us in terms of the way he can play, so it's certainly good to play with him.''


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Monday, 18 December, 2000, 14:39 GMT
Beatles album tops 2000's charts
An album of The Beatles' number one hits has been confirmed as the biggest-selling album of 2000, after only five weeks in the shops.
The record, called simply 1, toppled Moby's Play - which has been top best-seller for most of the year - at the weekend with sales figures reaching 1.3 million copies.
The album has stayed firmly at number one in the UK album chart since it was released on 14 November, and currently tops the charts in 28 other countries.
A spokesman for the three remaining members of the band thanked "everyone who appreciates good music".
The album has also already gone down in the record books as one of the fastest to sell one million copies in the UK.
It is also on course to become one of the biggest-selling albums of all time, particularly since it returned to the number one spot in the US album chart last week.
The number of albums currently ordered for sale abroad stands at 13.5 million.
The album brings together 27 of The Beatles' UK and US number one singles from 1962 to 1970, from Love Me Do to The Long And Winding Road.
In eight years the band redefined popular music and left a musical legacy as influential now as it was in the 60s and 70s.
The phenomenal popularity of the new album shows that, 30 years after the band split up, they remain as popular as ever.
Further proof, if needed, is that The Beatles' recently released book, Anthology, is in the top 10 of book charts across Europe.
Last week, Sir Paul McCartney caused a surge of excitement in a central London bookstore when hundreds of fans flocked to see him at a signing session for his book Paintings.
And on 8 December, people around the world paid an emotional tribute to murdered Beatle John Lennon on the 20th anniversary of his death.
See also:
13 Nov 00 | New Music Releases
CD Review: The Beatles
19 Nov 00 | Entertainment
Beatles album tops the chart
01 Nov 00 | Entertainment
Beatles to launch website
17 Nov 00 | Entertainment
Yesterday is top pop song
19 Oct 00 | Entertainment
Beatles' film producer dies
06 Nov 00 | Entertainment
Westlife: Pretenders to Beatles' throne?
09 Dec 00 | Entertainment
Lennon's family lead world tributes
05 Oct 00 | Entertainment
Beatles book draws fans
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A Superstorm Sandy relief fund run by the wife of Republican New Jersey Gov. Chris Christie has collected $32 million in donations in four months and reportedly has yet to disburse any of it.
However, Christie praised his wife's charity on Monday, saying he was "really proud of the job she's done and the professionalism she's brought to the job."
Christie "said the Sandy relief fund was never meant to provide immediate assistance to those recovering from New Jersey's worst natural disaster," and the "charity will provide rebuilding aid to Jersey residents whose homes and businesses were damaged by the storm and help cover gaps between repair bills and the amount covered by insurance."
The New Jersey governor addressed the issue after The Asbury Park Press newspaper "reported Sunday that none of the relief money that came pouring in after the late October storm had reached victims."
Christie's wife, who is "a hedge fund manager who took two months off from her job to oversee the charity," told the publication "she is being methodical to ensure the money is spent properly."
The New Jersey Republican slammed his party's House lawmakers for criticizing the pork-laden Hurricane Sandy relief bill last November after he participated in a photo-op with President Barack Obama during the last week of the 2012 presidential campaign. American Conservative Union Chair Al Cardenas cited Christie's attack as a reason he was not invited Christie to 2013's CPAC, which will be held this week.


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Adopting new medical technologies in Russian public hospitals: what causes inefficiency?
The adoption of new medical technologies in Russian public hospitals is an important part of healthcare modernization and thus is a subject for public finance and regulation. Here we examine the decision-making process on adoption of new technologies in Russian hospitals, and the institutional environment in which they are made. We find that public hospitals operate within a strategic-institutional model of decision making and tend to adopt technologies that bring indirect benefits to their heads/physicians. Unlike Western clinics, the interests of Russian hospital heads and physicians are driven by the possibilities to obtain income from a part of hospital activities: the provision of chargeable medical services to the population, as well as receiving informal payments from patients. The specifically Russian feature of the decision-making process is that hospitals are strongly dependent on health authorities' decisions about new equipment acquisition. The inefficiency problems arise from the contradiction between hospitals' and authorities' financial motivation for acquiring new technologies: hospitals tend to adopt technologies that bring benefits to their heads/physicians and minimize maintenance and servicing costs, while authorities' main concern is initial cost of technology. The main reason for inefficiency of medical technology adoption arises from centralization of procurement of medical equipment for hospitals that creates the preconditions for rent-seeking behaviour of persons making such decisions
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|Published in WP BRP Series: Public Administration / PA, November 2013, pages 1-31
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| Postal: Myasnitskaya 20, Moscow 101000
Phone: +7(495)7713232
Fax: +7(495)6287931
Web page: http://www.hse.ru/
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References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Danzon, Patricia Munch, 1982. "Hospital `profits' : The effects of reimbursement policies," Journal of Health Economics, Elsevier, vol. 1(1), pages 29-52, May.
- Feldstein, Martin S, 1971. "Hospital Cost Inflation: A Study of Nonprofit Price Dynamics," American Economic Review, American Economic Association, vol. 61(5), pages 853-872, December.
- Greer, Ann Lennarson, 1984. "Medical technology and professional dominance theory," Social Science & Medicine, Elsevier, vol. 18(10), pages 809-817, January.
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RICHMOND — A truly successful Coastal Cleanup Day is one where volunteers arrive at dozens of Bay Area locations and discover there is no trash left to clean up, according to one environmentalist.
Based on the amount of plastic foam, car tires and bottles hauled out from Bay Area rivers, sloughs and coastline Saturday, that day has not arrived.
Thousands of volunteers fanned out across the region's waterways, from Antioch to Oakland, San Jose to Marin County, as well as throughout the state, in one of California's largest volunteer efforts.
With more than half of cleanup areas reporting, more than 600,000 pounds of garbage and 57,000 pounds of recyclables had been collected in the state, according to Eben Schwartz of the California Coastal Commission. Final numbers will be available next month.
In Richmond alone, about 3,700 pounds of recyclables and garbage were taken off the coastline.
Despite all this trash removed by hand, counted, categorized and either recycled or thrown away, only so much can be done in a single day. Volunteers said the sheer size of the state's garbage problem is not something they can cure on their own.
"There's no way we could have got it all," said Jim McGrath, a Berkeley resident. "We just tried to get as much plastic as we could."
McGrath, along with a dozen other volunteers, traveled in kayaks to areas near Point Isabel in Richmond not accessible on foot. They brought back five kayaks full of discarded plastic and other debris, but were forced to leave much behind.
The limited resources marshaled to combat a growing global problem failed to dishearten those on hand at the Richmond shore.
David Helvarg, author and president of the environmental group Blue Frontier Campaign, said he purposefully chose a career of environmental activism because of the possibility of success. The Richmond resident said it offers more hope than his previous profession as a journalist covering wars overseas.
"There will always be wars, but there might not be living seas, protected wetlands or wild fish," Helvarg said.
Helvarg was at Shimada Friendship Park on Saturday to educate others on the necessity of our planet's oceans.
"We know what the solutions are," he said. "We just need to create knowledge and commitment to turn the tide."
More than 600 volunteers — a record — participated at the Richmond event, according to Contra Costa County Supervisor John Gioia. Hundreds of those donning gloves and buckets this year were teenagers.
Maria Martinez, a Richmond High School senior, arrived with four other members of the group Youth, Mentors and Educators to lend a hand. Martinez plans to study environmental science after she graduates, but also wanted to set an example to her high school classmates.
"I know a small change can make a big impact," Martinez said. "If they see trash they should throw it away because even little things accumulate."
Some changes have been made. Arian Sarris, of San Pablo, has volunteered many times to help relieve the region's waterways of garbage. She has noticed a difference in Californian's mind-set just by looking at the trash that eventually washes up on shore, she said.
Cigarette butts used to litter a beach for miles, but no longer, Sarris said. There's a bigger problem.
"There's a lot of plastic everything," she said.
Almost 30 billion plastic water bottles are used by Americans each year. Most of these are not recycled and many end up in the water and eventually in the ocean, according to statistics provided by the Watershed Project.
Those helping clean just a fraction of this waste know more education will help reduce the amount of trash they pick up every year.
"If we changed a few minds today, I'd consider that a success," McGrath said. "In the meantime, we'll keep picking up after them."


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QUESTION: I recently installed the "Smartstor" backup and restore utility. I didn't find it useful so I uninstalled it. However, during the installation that program created two new entries in the "right-click" menu: Backup and Restore. After uninstalling, those two entries still appear in the right-click menu when I select a file in Explorer. How do I remove them?
ANSWER: This is another example of an application trying to be helpful and doing a pretty poor job! When you install a new application, your system will often be changed in ways that aren't immediately obvious. Changes to the "right-click" (context) menus are a case in point.
These menus are called context menus because they are supposed to be intelligent enough to display a different set of options, depending on where and what you click. If I right-click an HTML file on my system, the resulting context menu offers me a choice of twelve or more actions. If I select Open, the file will open in Internet Explorer. If I choose Edit, the file appears in FrontPage 98 -- and so on. While choice is usually a positive, it's not always what you want. Context menus can become bloated with dozens of options, which forces you to waste time scrolling up and down in search of the item you need. To make matters worse, context menus aren't quite as bright as they should be: if you remove the application that created a context menu item, that item may be left behind -- inoperable but still taking up space on screen. A good uninstall routine will remove all such items; a bad one will leave debris all over your system.
Context menu information is stored in the Registry, but you don't have to edit it directly in order to put your Windows house in order: you can clean up by editing the file association details in Explorer. Here's how it's done.
In Explorer, choose View-Options and select the File Types tab. Scroll down the list of Registered file types until you find an affected type (if more than one file type displays a problematic context menu, you will need to repeat this procedure for each type). With the file type selected, click Edit. The Actions list will display all the context menu items for this type of file. Select the defunct action (on Danny's system this would be Backup or Restore) and then click Remove. Click OK and then Close to dismiss the dialogue boxes. The unwanted item will no longer appear in the context menu.
Now that you have removed all that dead wood, why not use the Options dialogue box to add some context items of your own? Let's take HTML files as an example. Normally, if you double-click an HTML file in an Explorer window, it will open in your default browser. That's probably what you want in most cases, but if you manage a Web site there will probably be times when you need to open the file in a text editor such as Notepad. To create the new context menu item, navigate to the Options dialogue box, scroll down the list of file types and select Internet Document (HTML) -- or Microsoft HTML document -- and click Edit. Click New. In the Action field, type a name for the item, eg Open in Notepad. In the Application used to perform action field, type the full path to the desired application, eg c:\windows\notepad.exe. Close the dialogue boxes and then test your changes by right-clicking an HTML file in Explorer. Open in Notepad should now appear as an option in the resulting context menu. Select it to open the file in Notepad.


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TAIPEI – Taiwan's National Palace Museum and the Tokyo National Museum are selecting 200 Chinese antiquities for exhibitions in Tokyo and Fukuoka in 2014.
The exhibitions will be held at the Tokyo National Museum for 12 weeks from June to September 2014 and eight weeks at the Kyushu National Museum in Fukuoka Prefecture from that October to November, according to a schedule announced by the museum.
Fung Ming-chu, director of National Palace Museum, said the museum hopes both sides will finalize the 200 items by the end of next month.
The themes of the exhibitions have yet to be finalized, and the items to be displayed are also being discussed, Fung said.
Items the Tokyo National Museum has expressed interest in include the famous Jadeite Cabbage and Meat-shaped Stone of the Qing Dynasty (1644-1911) as well as texts of Jin Dynasty calligrapher Wang Xizi (303-361). The Jin Dynasty ruled China from 265 to 420 and Wang is regarded by many as the godfather of Chinese calligraphy.
The Tokyo National Museum is also interested in paintings, scrolls, pottery and porcelain, bronze ware, carved lacquer ware, enamels and other Chinese antiquities from different periods, museum officials said.
The National Palace Museum in Taipei houses a large collection of Chinese antiquities, including scrolls, calligraphy, seals and vases collected by various emperors over a millennium.
The exhibitions will go ahead following legislation passed by the Diet in March 2011 that addressed Taiwan's concerns that China could seek to have the artifacts and artwork impounded without such a law.


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Michael Jordan, The Ultimate Rim Attacker [Video]
One of the many great things about YouTube is all the old sports videos. Reminiscing about the great Michael Jordan today, I felt the urge to watch a few old highlights. This video is the best of the bunch. Plenty of great players have attacked the rim, but none have done it like MJ did.
Chances are, you'll start watching this video to see a few highlights. Be warned, MJ's incredible game at the rim will draw you in. Before you know it, you'll have watched the entire video….but you won't regret it. I didn't.
Subscribe to Sports Radio ESPN 1420 on


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Lexus ES 300/ES 330
Toyota has some amazing technology on their assembly lines. In the past years they have retooled over a weekend, over an evening or even a shift change. In most likelyhood, they will not stop the line for the change. The last of the 2001's will be followed by a 2002. The really strange thing may be that they are pumping out some LS's then some who know's what for their domestic market, like an Arista or a Windham (the right hand drive version of the ES) and then the 2002 ES while the line is still running all during the same shift. I understand that they have no standing inventory and that if you order a Toyota in Japan on Monday they will have the car to you by Friday.
Any spy photos of the 2002 ES300? or any ideas of changes? I will be looking for a new car in May and want to know if it is worth waiting for. The Acura TL Type-S (due out late Spring/early Summer) sounds good right now but I would like to see what the ES will look like.
Has anyone had experiences with their stereo volume increasing by itself? It doesn't happen everyday. I can't fully explain when it happens, just that it seems to come up quite a bit. Enough to be noticeable, but not enought to have to turn it down.
I have the Pioneer with the 6 cd changer in a 2001.
rob175 Posts: 19Goodlanding.....the fact is that the volume does change, and it's supposed to. The radio automatically senses road noise (especially when you roll down the windows) and it increases the volume. The owners manual makes only one brief mention of this feature, so you might have missed it.
texplorer Posts: 9I think entry #295 probably has the best preview of the ES300's (can't be anything else). Even though it's in Japanese, you can cancel the translation programs if you don't have them, and click through the site to find the page that has "Photo" listed all over it (I think it's about in the middle of the page). You can get front and rear exterior shots as well as interior ones. Helped me in my decision to go ahead with a 2001 or wait for 2002.
I recently bought a Lexus es 300 and I offered
31,500, which i got it for. the car was value pack, heated seats, wood
steering, wheel locks, trunk mat and 16" tires.
There is only one dealer in the Buffalo area. Do you think this was reasonable? About tires, I have used the Dunlop d60a2 and it is a good tire for dry pavement and with reasonable gas mileage.
However, I do not recommend this tire for winter driving. my es has bridge stone re2 potenza and I am a bit disappointed. the car i test drove had michlens. Anyone else have thoughts?
PS.. the car is a 2001 es.
Wow, automatic volume control.
I felt sort of bad last night after "trashing" the best car I have ever had. I realized that if that's the only thing that causes me problems, then I don't have very much to gripe about. My last new car was a packed top of the line Chrysler. I counted 15 things wrong with it but was not too concerned as this was the average for the car. We bought a white one because you could not see as many paint defects on it. (All counted as one defect.) On the third day it would not start and the Auto Club could not start it. The dealers never did fix the problem. After 30 days in the shop over 10 visits to different dealers I ended up changing the starter motor with my own hands and out of my own pocket. I figured it was better than having a stroke. It has had 5 transmissions and controllers changed under warrantee. One dealer once said my warrantee was void for transmission number 4 because I had not changed the transmission fluid. I told him "Gee, you got me, I've been very busy. I like to change the fluid every other oil change but never got around to it. How often should I have changed it? Oh really, but the transmission only has 1,200 miles on it. How much will I have to pay?" I understand that the average car has had three transmissions. The first question the trade in guy asks is when the transmission was changed last. The wind noise is so great that the owner's manual says to drive with the window down about 1 inch.
I have the 5th recall notice on the kitchen counter right now. I wonder where I should send it.
What a joy the Lexus has been. I called the wife after the 1K service and told her we have to buy another. To have people treat people like people instead of stupid idiots that got suckered into paying too much for junk... wow, what will they think of next.
Thanks Rob175, for your quick reply. I will RTFM.
I don't believe post 295 is the new ES. The car shown is the Mark II, while the ES in Japan is the Windom. Since the Windom is also shown on the site, I doubt the Mark II is the new ES. Why would they be selling both the old and new versions at the same time? Also, being more of a luxury car, I don't think the new ES will switch from a foot brake to a hand brake (the Mark II has a hand brake). Then again, I could be wrong.
that is a very good price. I got mine with same options you described in late Oct for 32150 before TTL. go for it. don't wait too long you won't be able to get a certain color you want. I had this problem last year waiting for the 2000 model pricing to go down and ended up to get a 2001. Also, I heard that the number of 2001 ES300 will be limited this year because the manufacturer knows that a lot of people want to wait for the new 2002 model.
Lenscap is correct.
In the US we had the Corona, then the Corona Mark II, which became the Cressida in the late 70's. There were 3 body styles until the early 90's when they dropped the name with the MX83 Cressida. It was a wonderful RWD, 3.0L 24 valved inline 6 car. The next year the GS300 came out with the same running gear. What we are seeing on the link is a GS.
The Windom link is:
You might check it out if you have time. They show a DVD capable GPS and either 3 speakers or two speakers and a port on the rear deck.
Thanks for the info. The Windom looks like it could be the next ES300. I wish Lexus would put it in the showrooms early summer and not wait until Sept/Oct. I believe Acura may get some of their customers with the TL type-S.
dmallinder Posts: 35It starts downloading for me then self destructs at 39% every time ( and I'm on a T1 line ! ).
If anyone can I'd relaly appreciate it if they could find some interior dimensions on the 2002 Windom/ES300. I'm considering the car ( against mostly A6 but poss Avalon XLS and even Seville too ) but find it a little snug for my 250lb weightlifter build. Given even an inch or two more shoulder room it could be much more likely I get one. It has cost, reliability rep and resale value over the others by a long shot.
scorpion1 Posts: 2Could someone do me a favour and check in the manual and tell me what the exclamation ! light means on the dash. (after moving I haven't been able to find my manual.
While driving home today the light came on for a few seconds and then went off so I'm a little concerned. The car runs great, and just had a tune up only 10,000 m ago.
Can someone tell me what this light means, and should I be concerned since it only went on for a few seconds?
If it turns out like this:
I am new to this topic. I was wondering what the ES 300 will look like.
akid4ever Posts: 1First off, I would like to say "hi" to everyone. I got a lot of great information from
this board before purchasing my ES 300.
I purchased my Certified Per-Owned 98 ES 300 in December. I guess, you can say it was my Christmas present. This car replaces my 89 Nissan Maxima which now has 245,000 miles on it.
The rainy season has finally hit San Francisco. So, in the last couple of weeks, I noticed that the front passenger car mat was getting wet during heavy rain storms. At the top left corner of the car mat, where the mat meets the dash, I placed my finger in the small opening where the carpet joins, and felt drops of water. I suspected that somehow water was getting into the car. I called the Dealership and brought the car in today.
They hosed down the car three separate times, focusing on the moon roof, windows, and all the seals. But no leak... The mechanic mentioned that since I live in San Francisco, and there are quite a bit of hills that if the car was parked on an incline and during the rainstorm, the moon roof drain would overflow and drain toward the front of the car.
I'm just wondering if anyone else has encountered this problem? and what the solution might be. Any help would be appreciated!!
vernlew Posts: 87budny1,
What you experienced regarding the different sets of OEM tires is a common practice with all auto companies. They usually have several tire vendors, so it is hit-and-miss as to what brand your particular car will come with. I always check out the tires on the car I am going to deal on, and usually if it does not come with the wheels and tire brand I prefer from all the others I see on the vehicles on the lot, I will make a deal with the salesman to purchase the particular car I want, IF he changes out the wheels/tires for what I prefer, from another car, BEFORE I take delivery. Most dealerships will do this if you insist.
The Bridgestone RE2 Potenzas, however, are supposed to be very good tires.
hayabusa Posts: 26the Toyota Mark II Fortuna... Yeah yeah yeah... Toyota comes up with the weirdest names... Actually all Japanese manufacturers... Here's a link to the Toyota Mark II Fortuna's website:
This is just a beefed up Toyota Mark II...
akid4ever - I suspect the dealer is barking up the wrong tree in trying to diagnose your leak. You say that you feel wetness when you touch the rug up under the dash, at the corner of the mat, but you didn't mention wetness anywhere else on the rug. Therefore, it would seem very unlikely that it's a leaking moon roof or windows, which should wet the carpeting in many places if it's running along or under the carpet. Sounds more like a leak either from the heater or through the floorboard or firewall. If there is a small weld separation or other crack or hole in the floor or firewall, rain could be driven in when driving on wet streets. I suggest that, if possible, you spray some water from a garden hose onto the firewall near the carpet area where you feel the leak, taking care not to get it all over the engine or components. See if that shows anything. The other thing to try is to turn the heater and fan full on and see if you can feel any additional moisture coming onto the carpet. If it is a heater problem, you would eventually notice the radiator level going down (though probably over a long period of time) and possibly notice a greenish or orangish tint on the carpet, under a strong light, from anti-freeze coolant.
Good luck and let us know what happens.
alexu Posts: 1RECENTLY, I CHANGED MY LEXUS' DISPLAY LIGHT BULBS, AFTER THAT MY AIR BAG LIGHT ON. DOES SOMEBODY KNOW, HOW I CAN RESET THE COMPUTER ON MY LEXUS ES300 1996?MAIL YOUR COMMENTS TO ME (firstname.lastname@example.com)
vhirsch1 Posts: 2Anyone in the Dallas/Fort Worth (Texas) metroplex bought a 2001 ES 300 lately? I am looking to make an offer on one and wondered if $30K would be a decent starting point for one with the Value Pkg added (no other options)? Also, does anyone think the body style will change so drastically that it will be embarrassing to be driving the "old style"? There's nothing worse than having a brand new car that already looks dated!
That link I posted was a computer touched picture of a new Toyota.
No, it's not the Mark II, as the magazine is usually pretty accurate in their prediction.
(Actually, the spy picture of Mark II was posted in their previous edition of spy scoops).
The link from post 295 isn't a GS either, since that's the Aristo in Japan. Post 295 of the Mark II appears to be the Cressida (as it was called here), because on the history page the cars shown are the Cressidas that were sold in the U.S. Of course, when Lexus began they dropped the Cressida here. If the Camry photos above are correct, they look like the new Mark II/Cressida. However, with the Cressida being RWD and the Camry FWD, I guess they couldn't be the same car.
Some notes from my dealer on the new ES 300: There's a 20% chance it will be at the Chicago Auto Show on February 8, the doors will have frames around them, and other than the front end there is almost no resemblance to the current ES 300.
sless Posts: 10Well, it's the end of the month and I'm getting a great deal on an ES. The question is . . . would anyone not recommend this car or everyone happy with theirs. The style isn't great, but it sure is comfortable and the reliability and resale value is important to me. Any comments are appreciated. I'm a bit hesitant to bite the bullet only because I'm afraid after the 2002 comes out I'll regret not having waited. The 2001 style is very conservative and looks like so many other sedans. Thanks.
jwfslk Posts: 9I picked up my new Lexus on Saturday, it's my 3rd. White pearl with Value Pkg, heated seats, wood steering wheel, 16" whls (not chrome) and all-season tires, trunk mat and wheel locks for $31,250. I also got the salesman to throw in a cargo net for the trunk. I thought about waiting for a 2002, but changed my mind when my salesman told me the style will be more evolutionary, rather than revolutionary! All sheet metal will be changed, but not drastically. Guess we'll have to wait and see!
sddlw Posts: 361I just bought my first Lexus in August. A 2000 ES300, VP, HID, 16" chrome wheels. There are good and bad points to any car, regardless of how much you spend, but I think the ES300 for $31K is a good value and that is really what drove my decision.
I was driving a 92 MB 300E that I had purchased used in 1997 with 36K miles for less than the ES300 cost me new. In August 2000 it had a total of 75K miles on it and still looked practically new. If I could spend $55K on a new car and not feel the financial hit, or if I was comfortable spending $2,500 each year on maintanence for my older E-class, I'd never have left the E-series MBs. (The C-class just doesn't do it for me.)
I think the ES300 styling is very boring, but the car has a really nice balance of interior amenities and rides pretty well. Not as stiff as a sports sedan, but not a boat either. Also the residual value is good, maintanance is low and the overall cost of ownership over 5 or so years is rather modest.
However, if styling or performance are your most important criteria, this car might not be for you. There are many cars on the road with more inspired styling than the current ES300. There are quite a few with better performance. Many with nicer interiors, but few alternatives with the balance I was looking for at the price I was willing to spend.
what did you have to do with your MB? Why did you have to spend at least 2.5K every year on maintenance?
sunami Posts: 2Hello from a new member and thanks for your comments which helped me to decide to buy a 2000 ES300 in September. After the first oil change at 5000 miles ,.the oil level on the dip stick now reads about a quarter inch above the full dot. The service writer says not to worry but the manual states anything above the mark is too full and could lead to engine damage. Any comments on this from you veteran owners and experts?. Also ,the rear brakes are squealing more when they are applied rather than just when backing up. The dealer says this is the type of metal used in the pads and there is no permanent fix.He states that this happens during the cold weather in the upper mid west and the noise will disappear with warmer temperatures. It's embarassing to pull up to a stop sign with the brake noise. All else about the car is great . Thanks for your ideas and an interesting Town Hall.
how cold is the weather where you live? I live in Virginia where the weather is around low 30's during daytime. i don't have the kind of problem you have. i have couple of friends living in Minnesota that own Lexus, I don't hear from them any complaints about the brakes. A Lexus should not make any noticeable noise, in my opinion.
Agree with liev that a Lexus should not make noise under any normal condition, and cold weather surely is a normal condition in the North. It sounds like whoever you talked with at the dealer is being dismissive and doesn't want to work with you.
I suggest that you telephone your Lexus dealer, ask for the service manager if that's not who you dealt with before, and explain your problem. If you did deal with the service manager, ask for a service technician or someone other than the manager and see what he/she says. If you don't get the answer that you want (ie., the brakes should not squeal noticeably in the cold and there's a problem if they do), either call another Lexus dealer if there is one in your greater area, or call a Toyota dealer service department or two and ask the same question. Maybe even call a brake shop or two. What you want is one or more authoritative sources to tell you that your brakes shouldn't squeal, so that you can take that info from that source(s) to your Lexus dealer service manager, your sales rep, or dealership management. If nothing else works, call the Lexus Customer Service Help Line which serves as a go-between for the customer in getting problems resolved with local dealership.
And I'm also mystified about your statement that your brakes are squealing when they are applied, "rather than just when backing up." Lexus brakes (and as far as I know the brakes on any other car as well) should NOT squeal or make any noise when backing up. You might also ask those you call about that too if it is happening with your car.
Good luck.
I also notice a squealing when applying the brakes, specifically from the left rear. I thought it was because the car was new. (It only has 800 miles.) I have my 1 month check this week so hopefully someone can give me an answer. I thought also it had something to do with the type of metal used in the pad. With a 2001 es, I wasn't expecting this kind of nuisance. Anyone have other opinions?


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Permanent link to MTA daily�media news
Randi Rhodes is the Victim of a Violent Attack
Randi Rhodes was mugged on Sunday night on 39th Street and Park Ave, nearby her Manhattan apartment, while she was walking her dog Simon. According to Air America Radio late night host Jon Elliott, Rhodes was beaten up pretty badly, losing several teeth and will probably be off the air for at least the rest of the week. At of late Monday night we have not able to locate any press accounts of the attack and nothing has been posted on the AAR website.
There are discussions on the Randi Rhodes Message Board and Democratic Underground where you can wish Randi well.� I no longer have an email address for her.
Violent Crime Captures the Headlines: October 7 – 12, 2007
While crime coverage may seem like a staple of our news diet, last week was actually unusual in that three frightening stories of random violence generated coverage�with two making the top-10 story list. Plus, the media are all over Fred Thompson�s debate debut.
Microsoft�s Ballmer kicks off ANA show with claim that all media will be digital in 10 years
Phoenix�In his opening keynote presentation at the Association of National Advertisers� annual conference, Microsoft Corp. CEO Steve Ballmer said that in 10 years, all media will be digital, with tremendous ramifications for marketers, agencies and publishers.
Facing the News Business Model Crisis (by Rich Gordon)
The destruction of the print business is leaving an online business too small to support the cost of creating original content at all but the largest scales. Large-scale content markets — say,national sports or national business, possibly even a few national news providers like the Times — are now large enough (or close) to pay people to create content. What happens in Raleigh, N.C.? Or Peoria, Ill.? Or Carlisle, Pa.?
Paying for investigative journalism (by Jeff Jarvis)
I think that if we analyze the staffing and production devoted to investigation in American journalism, we�ll find that it�s a pretty damned small proportion of news budgets. And I suspect we�ll find that if it is not supported by large media organizations, it could be supported by foundations and public donation. That could come from independent organizations like Pro Publica and other� It also could come from independent journalists like Josh Marshall. There is one caution to this: These organizations can be backed by and run by people with axes to grind. And so we may find an imbalance in investigation. That�s why the role of the editor, the journalist upholding public standards, remains important.
You mean like the editors of the Wall Street Journal and Washington Post editorial pages, Jeff?
Getting it wrong, letting it slide (by Edward Wasserman)
Why is it that the mightier the news organization, the likelier it will stand by ethical blunders that would shame a first-year reporter? Apparently, along with industrial mastery comes the right to deny, evade, whine and nitpick instead of owning up to what you did wrong and making sure you don't do it again.
On Friday evening, Air America�s Mark Green did something astounding. Breaking every known modern pundit convention, he actually told the truth! Green actually blamed the mainstream press corps for its disgraceful conduct toward Candidate Gore!… If other liberals had spoken this way in the course of the past seven years, we�d be living in a vastly different political country� Green was speaking with Hardball�s Chris Matthews�and no one trashed Candidate Gore in quite the way that Matthews consistently. No one lied about Gore so incessantly. No one was uglier, ruder, more insulting.
General Advocating Victory Declaration Over Al Qaeda Pushed Bogus Storyline About Pat Tillman (by Greg Sargent)
[Monday�s] Washington Post reports that some generals believe that Al Qaeda in Iraq has been vanquished and want the U.S. to publicly declare that we have defeated the terror group. The leading general urging such a declaration of victory over AQI is Lt. Gen. Stanley McChrystal� But some interesting facts are dribbling out about General McChrystal. As Think Progress notes, he declared "major combat over" — way back in 2003� [And i]t turns out that General McChrystal also got into trouble for pushing the bogus storyline that now-legendary former NFL player Pat Tillman had been killed by enemy fire in Afghanistan.
The Murdoch Media Service Obliges GOP Lies (by Marcy Wheeler)
Gosh, what a remarkable coinkydink. This morning, Roll Call comes out with this story: �Specifically, Republicans are planning to use the kidnapping and subsequent murder of three U.S. soldiers in Iraq earlier this year to put a �human face� on the [FISA] issue�� And on the very same day, Murdoch's rag comes out with this story. �U.S. intelligence officials got mired for nearly 10 hours seeking approval to use wiretaps against al Qaeda terrorists suspected of kidnapping Queens soldier Alex Jimenez in Iraq earlier this year, The Post has learned.� [But] those soldiers died because [no Justice Department official was available to sign the warrant,] not because of any laws on our books. But god forbid the Republicans would actually leak the truth to compliant media outlets to accomplish their agenda.
Welfare as We Should Know It (by Dean Baker )
The NYT reports that the Treasury Department is coordinating the creation of a bailout fund that will be financed by several major banks, which will act to support the market in some of the exotic investment vehicles that they developed over the last decade. This should be reported as what it is, a bailout by the nanny state for the big boys who lack the ability to get by on their own in a free market.
The Battle of the Budget (Public Opinion by Ruy Teixeira)
The public favors increased domestic appropriations, but the Bush administration and their conservative allies refuse to listen.
Calvin Coolidge Redux
After rightly noting that presidential candidates "almost invariably" are "a bunch of very rich people," [Gail Collins�] op-ed goes on to claim that "voters tend to admire wealth."� Falling into a familiar pattern documented by FAIR over the years of the media trying to �weed out� candidates who do not meet the press corps� ideological preferences, she calls for TV debates to exclude all but the candidates with the most campaign money to spend.
Media Matters for America headlines
George Will: GOP voters "have learned" that Giuliani "doesn't flip-flop"
Reliable Sources panel questioned why Coulter keeps getting invited on television
CNN's Collins did not challenge CEI fellow's distortion of Gore's sea level claim
Wash. Post article on earmarks quoted Stevens but not prior Post report that Stevens' earmarks are being investigated
MSNBC labeled global warming skeptic Gray a "top meteorologist"
MSNBC's Brewer claimed "even conservative Republican presidential candidates are trying to sidestep" SCHIP — but several support veto
CBSNews.com article contains language nearly identical to WorldNetDaily article, including falsehood
Wash. Post advanced myth that social conservatives are only constituency who vote their values
Wash. Post quoted White House saying not for Congress to "work[] out" whether Armenians suffered "genocide" — but Bush himself did in 2000
WSJ editorial said Bush supports a "20% expansion" of SCHIP — not according to CBO
Coulter: "I don't think most Jews are as stupid as Donny Deutsch"
SC justices: Thomas�s biography �unseemly.�
Supreme Court justices reportedly are aren�t thrilled with Clarence Thomas�s new biography. The NY Posts�s Cindy Adams writes, �Phrases swatted about are �unseemly� and �breach of decorum.� Besides unraveling his life story, he has also delved into the ways and hows of the Court. They feel it �irresponsible� for a sitting Supreme Court Justice to write about The Process.�
Bill Cosby's New Book Full of Racial Stereotypes
Cosby's new book continues to tar black communities and the black poor as dysfunctional, chronic whiners, and eternally searching for a government hand-out.
Leno keeping NBC up at night
As part of a high-stakes gambit engineered by NBC Universal executives three years ago, Leno agreed to step down in 2009 as "The Tonight Show" host to make room for Conan O'Brien. Afraid that O'Brien, whose talk show airs after Leno's, would bolt to a competing network, taking his desirable young audience with him, NBC locked up his services by promising him "The Tonight Show." But as the date has drawn closer, Leno has become frustrated, reluctant to retire from late night.
A Perky Debut for the Fox Business Network
The mood on Rupert Murdoch�s latest television venture was so giggly and upbeat that it belied its own crawl, showing sinking stock prices.
Market Movers
For all that blogs are becoming increasingly mainstream, the number of people who get a regular and predictable paycheck for blogging is still tiny. That number will rise, but it will never come close to the number of people who get a regular and predictable paycheck for old-fashioned reporting. In most of the blogosphere, the incentives and the rewards for generating content are very, very different from what is found in old-media companies.
Our need to put food on the table, on the other hand, is very, very similar.
World's first TV-quality online network launches
CANNES, France (AFP) – The world's first TV-quality online television network went on display at this week's MIPCOM audiovisual trade show offering legal, free entertainment and raising questions about what this will mean for the massive TV business.
Digital deal nudging music into living rooms
DENVER (Billboard) – For Real Networks' Rhapsody digital music service, there's no place like home. The company has teamed with TiVo to bring subscription-based on-demand streaming music into the living room directly from Internet-connected TiVo digital video recorders. For subscription music services and Internet radio outlets, the deal serves as a blueprint for how Internet-based music can crawl out of obscurity and into the mainstream.
Nielsen Launches New Services to Track Web and Mobile Usage
The Nielsen Company has release two new services � Nielsen Online and Nielsen Mobile. Nielsen Online combines data from Nielsen//NetRatings and BuzzMetrics to measure not only traffic, but penetration in blogs, social networks, and other forms of user-generated content. Meanwhile, Nielsen Mobile offers data on how people use their mobile devices, such as usage of the mobile Web and their favorite brands.
Update TV Spots — Even After They're Recorded
BlackArrow Aims to Place Relevant Ads in DVR, VOD and Broadband Programs
Google Reader Stats are Bullshit (With Proof) (by Pete Cashmore at Mashabel)
Google Reader stats, in case you don�t know, are bullshit. In fact, all Feedburner stats for most top blogs are bullshit due to the effect of default feeds. Want 80,000 free subscribers? How about 200K or more? Read on.
Biz-News Outlets Grow, but Will Ad Dollars?
It's Tough for Brands to Stand Out in Crowd That Now Includes Fox, Too
AOL to Trim 2,000 Jobs in a Continuing Overhaul
The cutbacks are part of a plan to reorganize the company and focus on advertising-supported Web sites and on selling advertising on behalf of other companies.
Google skimps on its own advertising
SAN FRANCISCO – Like a gourmet chef who rarely eats out, Google Inc. feeds advertising services to hordes of other businesses while skimping on its own marketing.
Maybe Google skimps in dollars spent, but every appearance of Google Ads on millions, if not billions, of websites is an ad for Google.� Not only that, but the company announces two or three new things they�re doing every single day, which gets lots of free media coverage.
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In Focus / Developer Karl Frizlen
Transforming an old warehouse that once housed a well-known antique shop into a multi-use complex that includes upscale loft apartments, a restaurant and small food manufacturers was a challenging mission.
But the developer of Horsefeathers Market & Residences says the project on Connecticut Street on the West Side has been a success. Karl Frizlen, president of the Frizlen Group Architects, said the complex has been attracting customers and tenants from outside the city.
Frizlen talked with The Buffalo News' Brian Meyer about how finding new uses for old buildings is important to the revitalization of neighborhoods. Here is a summary of issues covered in an interview that is part of the weekly "In Focus" series. Watch the full interview above.
Meyer: Talk about some of the challenges that you faced in redeveloping this huge structure.
Frizlen: The biggest challenge I would say was probably financing. There are not too many lenders who would tackle a project like this. It's mostly due to the location and due to the nature of this project. It's a mixed-use. They're much more difficult to finance.
Meyer: There was a couple years of delay partially because of that.
Frizlen: That's correct.
Meyer: What can be done to make it easier to finance these kinds of ambitious projects?
Frizlen: Foster a better understanding of what the nature of this project is – what it's really doing to the neighborhood ...
Meyer: Let's talk about what one West Side activist said. She suggested that there is a renaissance going on here in the Connecticut Street area. Is that an overstatement, or is that an accurate depiction?
Frizlen: There's definitely more interest by people purchasing properties here on Connecticut and on the West Side in general. It's a good time to be here. We were in here in rather early stage, and ... We see it now coming along a lot better than two or three years ago.
Meyer: What's causing it?
Frizlen: Here on Connecticut, there are two really major pieces in place. That's D'Youville College on one end. You know, one bookend. And the other bookend is the Elmwood Village. We're kind of in-between. We're trying to link these two neighborhoods. That's attracted us here to Connecticut ... [Building thriving neighborhoods] is tremendously important. Only strong neighborhoods create the strength of the city. If one neighborhood is kind of weak and the other one is strong, we have to find the balance. We have to develop not only here on the West Side, but ultimately also we have to tackle the East Side, which is still lagging behind a little bit.
Meyer: How successful are you at bringing people from outside of the neighborhood and even outside of the city to Horsefeathers?
Frizlen: I would say at this point about 60 percent of our tenants in the building are from outside the city. And many are from outside the state. We're attracting a lot of people. They work at the medical campus. ...We're attracting a lot of those people.It's important to also bring outsiders, so to speak, to the West Side and demonstrate that it's really a livable neighborhood and that it's an emerging neighborhood, and that ultimately something really good is going to happen here.


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The 2010 BMW X6 also has an ample list of standard features, including 10-way power-adjustable seating for driver and front passenger, HD Radio, wood-grain trim, automatic front climate control, push-button start/stop, power tailgate, front and rear parking sensors, a 10-speaker stereo with two subwoofers, dynamic cruise control and more. Optional upgrades include four-zone automatic climate control, ventilated front seats, iPod and USB connectivity, a premium hi-fi stereo system, six-disc DVD changer, voice command, navigation, real-time traffic, a rearview camera, and a range of interior and exterior appearance packages.
"The X6 also comes with every other conceivable kind of gizmo, which while impressive, would make us worry about buying an X6 as a used car in a few years' time," Jalopnik warns. On the other hand, if you opt for the X6 M, Autoblog says you can rest assured you're driving "one of the most formidable, meticulously engineered, tech-rich crossovers on the planet."
A high-end audio system, a navigation system, Bluetooth wireless connectivity, and a range of wood trim make for a very configurable buying experience. "There's even a heater for the [steering] wheel if you desire," Truck Trend says, and in between the rear seats, there's a "handy console for drinks and gear." The X6 M model doesn't add a lot of gadgetry-and it doesn't need to, instead focusing on the performance side of the equation.
Car and Driver points out the 2010 X6's base price of about $56,000 for the six-cylinder X6 and $66,000 for the V-8 version, while the new X6 M joins the party with a starting price just under $90,000. The price rises quickly when you start adding Sport packages, navigation systems, and top-line stereos; even the lesser version can top $70,000, notes Car and Driver. "Plan on $80,000 for one with all the goodies," they add. The X6 M's price seems even tougher to swallow, but it still "undercuts the Porsche Cayenne Turbo by a considerable margin," says Autoblog. Edmunds isn't so sure about the price either, asking whether the X6 is worth the premium over its X5 sibling: "An extra $8 grand for a little more motor, fewer seats with less room and an all-wheel-drive system you'll hardly ever know is there?"
Audio, climate, and navigation systems are all handled through BMW's capable but oft-criticized iDrive system. Most of the reviews TheCarConnection.com sampled call out the iDrive's complexity, but one review finds it has improved. "The iDrive is better than ever as well," Jalopnik argues. "Spend a few minutes getting used to it and you'll be rewarded with rapid, intuitive access to all the vehicle's settings."


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Research Topics
Marc J van de Vijver
Affiliation: The Netherlands Cancer Institute
Country: The Netherlands
Detail Information
- Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapyJ Hannemann
Division of Experimental Therapy, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands
Br J Cancer 95:1334-41. 2006..Possibly, the difference of the cumulative dose of only 25% between the treatment arms was insufficient to yield a survival difference...
- Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcomeI F Faneyte
Department of Pathology, The Netherlands Cancer Institute, Amsterdam
Br J Cancer 88:406-12. 2003..Proliferation decreases significantly after chemotherapy. ER negativity and a high proliferation index are associated with better response. HER2 status does not predict response, and outcome is not related to tumour response...
- Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patientsJ A van der Hage
Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands
Br J Cancer 90:1543-50. 2004....
- Predicting a local recurrence after breast-conserving therapy by gene expression profilingDimitry S A Nuyten
Department of Radiation Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Breast Cancer Res 8:R62. 2006..Here we have used gene expression profiling by microarray analysis to identify gene expression profiles that can help to predict local recurrence in individual patients...
- Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomasBas Kreike
Division of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Breast Cancer Res 9:R65. 2007..We examined the histopathological and gene-expression profile of triple-negative tumors to define subgroups with specific characteristics, including risk of developing distant metastases...
- A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancerFabien Reyal
Department of Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Breast Cancer Res 10:R93. 2008..we address the following issues: Do these signatures perform similarly? Are there (common) molecular processes reported by these signatures? Can better prognostic predictors be constructed based on these identified molecular processes?..
- Classification of ductal carcinoma in situ by gene expression profilingJuliane Hannemann
Division of Experimental Therapy, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Breast Cancer Res 8:R61. 2006....
- Efficacy of adjuvant chemotherapy according to hormone receptor status in young patients with breast cancer: a pooled analysisJos A van der Hage
Leiden University Medical Center, Department of Surgery, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
Breast Cancer Res 9:R70. 2007..Therefore, we studied the effect of adjuvant chemotherapy in young patients with breast cancer in relation to hormone receptor status...
- EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancerAlexandra M Pietersen
Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066X, The Netherlands
Breast Cancer Res 10:R109. 2008..This histone mark recruits the BMI1-containing PRC1 that silences the genes marked by PRC2. Based on their role in stem cells, EZH2 and BMI1 have been predicted to contribute to a poor outcome for cancer patients...
- Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stabilityMartin H van Vliet
Information and Communication Theory Group, Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Mekelweg 4, 2628 CD Delft, The Netherlands
BMC Genomics 9:375. 2008..This provides a unique opportunity to employ a substantial dataset to investigate the effects of pooling datasets on classifier accuracy, signature stability and enrichment of functional categories...
- SIRAC: Supervised Identification of Regions of Aberration in aCGH datasetsCarmen Lai
Bioinformatics Group, Delft University, Delft, The Netherlands
BMC Bioinformatics 8:422. 2007..Therefore, the identification of DNA amplifications or deletions across tumors may reveal key genes involved in cancer and improve our understanding of the underlying biological processes associated with the disease...
- Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring studyMarc van de Vijver
Netherlands Cancer Institute, Amsterdam, The Netherlands
Breast Cancer Res 9:R68. 2007....
- Emerging technologies for HER2 testingMarc van de Vijver
Department of Pathology, The Netherlands Cancer Institute, NL 1066 CX Amsterdam, The Netherlands
Oncology 63:33-8. 2002..While such technologies show great promise, they will at least have to be validated against IHC or FISH before being accepted into routine clinical practice...
- Gene-expression profiling and the future of adjuvant therapyMarc van de Vijver
Department of Pathology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Oncologist 10:30-4. 2005..com) in breast cancer patients. It is expected that in the coming years an increasing number of novel prognostic and predictive tests will help in guiding the adjuvant systemic treatment of breast cancer and other malignancies...
- The diagnosis and management of pre-invasive breast disease: pathological diagnosis--problems with existing classificationsMarc J van de Vijver
Netherlands Cancer Institute, Amsterdam, The Netherlands
Breast Cancer Res 5:269. 2003..If there is doubt about the classification of an intraductal proliferation, a differential diagnosis and the reason for and degree of uncertainty should be given, rather than categorizing a proliferation as atypical...
- Multidrug resistance associated genes MRP1, MRP2 and MRP3 in primary and anthracycline exposed breast cancerIan F Faneyte
Department of Experimental Therapy, Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Anticancer Res 24:2931-9. 2004..Multidrug resistance associated proteins MRP1, MRP2 and MRP3 confer in vitro multidrug resistance. We investigated their role in breast cancer resistance to anthracycline-based chemotherapy...
- Sentinel lymph node biopsy for localised ductal carcinoma in situ?P Veronesi
Division of Breast Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy
Breast 14:520-2. 2005..If the SLN is micrometastatic complete axillary dissection is not unavoidable...
- Radiation-associated breast tumors display a distinct gene expression profileAnnegien Broeks
Division of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 76:540-7. 2010..Approximately 90% of the breast cancers in these patients can be attributed to their radiation treatment, rendering such series extremely useful to determine whether a common radiation-associated cause underlies the carcinogenic process...
- Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy responseJorma J de Ronde
Department of Bioinformatics and Statistics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Breast Cancer Res Treat 119:119-26. 2010..For Luminal(IHC) and triple negative(IHC) tumors, further subdivision into molecular subgroups does not offer a clear advantage in treatment selection...
- A conditional mouse model for malignant mesotheliomaJohan Jongsma
Department of Molecular Genetics, Cancer Genomics Centre, Centre for Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Cancer Cell 13:261-71. 2008..Interestingly, upon Ink4a loss in the latter mice median survival was significantly reduced and all tumors were highly invasive, suggesting that Ink4a loss substantially contributes to the poor clinical outcome of malignant mesothelioma...
- A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patientsHongyue Dai
Rosetta Inpharmatics LLC, A wholly owned subsidiary of Merck and Co Inc Seattle, Washington, USA
Cancer Res 65:4059-66. 2005..Our work presented here may contribute a crucial step towards rational design of personalized treatment...
- Determination of stromal signatures in breast carcinomaRobert B West
Department of Pathology, Stanford University Medical Center, Stanford, California, USA
PLoS Biol 3:e187. 2005..Our findings suggest that the host stromal response varies significantly among carcinomas and that gene expression patterns characteristic of soft tissue tumors can be used to discover new markers for normal connective tissue cells...
- Improving patient care through molecular diagnosticsEdith A Perez
Mayo Clinic, Jacksonville, FL 32224, USA
Semin Oncol 31:14-20. 2004..The use of these systems will allow further development of customized therapies directed toward the particular molecular defects in a given cancer...
- Current perspectives on HER2 testing: a review of national testing guidelinesMichael Bilous
Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
Mod Pathol 16:173-82. 2003..The key point underlined by this review is that whatever method is used to test for HER2 status, the technology must be validated first, and there must be regular internal and external quality control and quality assurance procedures...
- Lung metastasis genes couple breast tumor size and metastatic spreadAndy J Minn
Department of Radiation and Cellular Oncology, Center for Molecular Oncology, and Ludwig Center for Metastasis Research, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 104:6740-5. 2007....
- American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancerAntonio C Wolff
American Society of Clinical Oncology, Alexandria, VA, USA
J Clin Oncol 25:118-45. 2007..To develop a guideline to improve the accuracy of human epidermal growth factor receptor 2 (HER2) testing in invasive breast cancer and its utility as a predictive marker...


text:
Will C. Wood's girls golf team downed host Vintage 264-276 at Silverado's South Course in Napa.
Marina Camacho, Kalanna Eldridge and Ashley Garner all shot 52 for the Wildcats (11-3 in MEL matches). Kaite Woo added a 54, and Hannah Scott shot 56.
Wood hosts Vacaville on Thursday at Cypress Lakes.


text:
The Reverend Professor Edward Caldwell Moore, chairman of the Board of Preachers, will conduct prayers this morning and every morning this week at 8.45 o'clock.
The preacher conducting the morning service may be found in Wadsworth House 1 every morning during his term between 9 and 11 o'clock.
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Read more in NewsEVENTS ADDED TO INDOOR MEET


text: To experience the small local river, Græse Å, a very good starting point will be a few km west of Slangerup at Hørupbro and Åbrinken. Here you will find a unique opportunity of seeing the typical open landscape and the nature up close. If you follow the trail marked with yellow triangels on small poles, you will get to see Græse Stream, the hilly scenery and a look back to the Ice Age in the small gravel pit. If you are interested, please contact Mr. Jørgen P. Sørensen at phone: (+45) 47 312 429 and he will supply you with all the details you need.


text:
Hrithik Roshan gets a legal notice for hurting religious sentiments of the people
Wed, Mar 30, 2016, 01:37 PM
Bollywood actor Hrithik Roshan made the news for wrong reasons. The actor's tweets turned controversial. Hrithik Roshan took a strong dig against Kangana Ranaut. His tweet suggested that he would rather have an affair with the Pope than Kangana. Abraham Mathai, the former Vice-Chairman of the States Minorities Commission, has filed a suit against Roshan for hurting religious sentiment and demanded an unconditional apology.


text:
It Takes a Hard Lovin' Woman To Love A Hard Headed Man
Recorded by: Mark Collie
Submitted by RoC
Note The Chord changes are so quick in this song it was kind of hard to write
them all in the right place, so listen for timing.
Intro (2x) E A A E B E
Verse One
(E)Everybody (A)said that (B)bobby was a (A)little hard (E)
headed(A) (E) (B)
(E)if there every was a (A)book on love, (B)Bobby (A)never
(E)read it. (A) (E) (B)
(E)Susie was a (A)poor boys dream (B)in a (A)high school (E)
sweeter.(A) (E) (B)
(E)She was ready to (A)run but her (B)daddy wouldn't (E)let
(C#m)She told mama how she love her man,
(A)and how daddy didn't under stand.
Why she was crying mama shook here head,
(B)she took her by the hand and said
It takes a (A)hard lovin' (E)woman (B) (E)
Takes a (A)hard lovin' (E)woman (B) (E)
It takes a (C#m)hard lovin woman (A)to love a (B)hard headed (E)man. (Back to intro)
Verse two
Bobby got a job at the west end filling station.
He was saving for a diamond ring after graduation.
Susie's dad came by for some gas and water,
he said boy stay away from my daughter.
2nd Pre-Chorus
That night by the light of the moon,
Bobby climbed up to susie's room.
Mama saw her pullin' out of the drive,
she didn't wake up daddy this time.
Back to Chorus
3rd Pre-Chorus
The June Wedding was a big affair.
Daddy if bought a Tux to wear.
The peacher told him as joined there hands
Love when you hurt, laugh when you can,
keep holdin' on till you understand...
Back to Chorus


text:
Profiling Rockbox(from docs/TECH) Rockbox contains a profiling system which can be used to monitor call count and time in function for a specific set of functions on a single thread. This can be used to optimize frequently-called functions or code blocks. To use this functionality:
r3 - 28 Jul 2008 - 22:47:05 - MichaelGiacomelli
Copyright © by the contributing authors.


text:
Who you gonna call? The Blur Busters! For Everything Better Than 60Hz™ Skip to content
Falkentyne wrote:Hi. Please read the forum. This question has been asked and answered multiple times now, including today.
The strobe utility is designed to be used with a VT 1350 (or VT 1500) tweak at 120hz. If you want to use other refresh rates, like 100hz, or DONT want to use a VT tweak at all, you are best off using the service menu so you can use a strobe phase of 100 (lower input lag) or 0 (less crosstalk, up to 1 frame higher input lag).
The windows utility prevents you from going too "high" on the strobe phase when a VT Tweak is used (going too high will shut off the backlight).
Return to BENQ Blur Reduction & Strobe Utility
Users browsing this forum: Bing [Bot] and 3 guests


text:
The RAM motorcycle handlebar base contains a 1.5" rubber ball designed to sit at right angles to the mounting rail. The rust proof metal u-bolt accommodates rails in 1" to 1.25" in diameter. The base also includes black cover caps to be placed over the exposed ends of the u-bolt.
RAM Mounts is a corporate brand of National Products Inc. (NPI) in Seattle, Washington. NPI offers an adaptable set of manufacturing capabilities with centralized manufacturing, production, and distribution operations. This means you receive the strongest mount available and the most innovative technology.
The rubber ball and socket design offers a secure hold with infinite options and vibration dampening for demanding environments.
Our philosophy is simple—build the best products available. And so our warranty is simple too. If we built it, we guarantee it. We are confident in the quality of our products, and with our warranty, you can be too.
We don't use call-centers, we don't outsource labor, and we don't ship opportunities overseas. Our all-American staff designs, manufactures, assembles, and sells our products right here, and ships them straight to you.
U-Bolt Dimensions:
Accommodates rails 1" to 1.25" in diameter.
Powder Coated Marine Grade Aluminum
Ball Size:
1.5" Rubber Ball Size
The "U" in the part number reflects product packaged in poly bag.
0.29 lbs.


text:
Obama Campaign Flags 'Less-Than-Reputable' Romney Donors
ABC Digital
Political News
Updated at
(CHICAGO) — President Obama's re-election campaign is circulating a list of eight "wealthy individuals with less-than-reputable records" who have donated to presumptive Republican nominee Mitt Romney.
"Quite a few have been on the wrong side of the law, others have made profits at the expense of so many Americans, and still others are donating to help ensure Romney puts beneficial policies in place for them," the campaign said in a statement from its "Truth Team."
Team Obama alleges four men, who have each given more than $100,000 to support Romney and an affiliated super PAC, have benefited from "betting against America" — specifically through outsourcing.
The list includes Paul Schorr, a partner at Blackstone Group, the nation's largest private equity firm; investors Sam and Jeffrey Fox of the Harbour Group; and T. Martin Fiorentino, who has lobbied for Lender Processing Services, a firm that has been penalized by the government for its mortgage servicing and foreclosure practices.
The Obama campaign also suggests that contributions from a group of deep-pocket "special-interest donors" are aimed at pushing a specific agenda, specifically on behalf of the U.S. oil industry.
The campaign's blog post names oil investor Louis Moore Bacon, oil refining company CEO Thomas O'Malley, registered oil industry lobbyist Kent Burton and businessman Frank Vandersloot as figures "donating to help ensure Romney puts beneficial policies in place for them."
President Obama, unlike Romney, voluntarily discloses the names and contribution amounts of all his top volunteer fundraisers — "bundlers" — not just those who are registered lobbyists, as required by law. Obama also refuses donations from registered lobbyists or PACs.
But Obama has received support from hundreds of wealthy Americans — including some with less-than-reputable records of their own.
Perhaps most notably, Hamilton E. James, the president and chief operating officer of Blackstone Group, who has likely benefited from some of the same investment practices for which Romney's donor Paul Schorr is criticized. James is a major Obama supporter, who has donated $35,800 — the legal maximum to the Obama Campaign and the Democratic National Committee in November of last year, according to Federal Election Commission records.
James will also host a fundraiser for the president in May that is expected to draw more donations from the private equity sector, a source told the New York Times.
Former New Jersey Gov. and Obama bundler Jon Corzine has been under investigation for his role in the collapse of investment firm MF Global, where he was chairman and CEO and from which more than $1 billion disappeared.
The Obama campaign and Democratic National Committee later announced they would refund more than $70,000 in contributions from Corzine and his wife. Officials said they would examine on a case by case basis whether to refund some of the more than $430,000 in additional funds Corzine delivered to the campaign from other supporters.
In February, the Obama campaign refunded more than $200,000 from Carlos and Alberto Cardona after the New York Times reported the brothers' ties to a Mexican casino magnate and fugitive from the U.S. who had sought a presidential pardon.
Earlier this month, another major Obama donor, Abake Assongba, made headlines for a civil lawsuit alleging that she stole $650,000 in an email scam to help build a multimillion-dollar home. Assongba has bundled more than $50,000 for the campaign.
Copyright 2012 ABC News Radio


text:
My partner of 12 years has dumped me because he said he does not love me but I love him with all my heart and we were engaged to be married.How can I get him back
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Partner of 4 1/2 years has cheated on me & left me for the person. [ 3 Answers ]
Hi, My partner of 4 1/2 years has cheated on me and left me for the person she cheated on me with. I am so confused and hurt that it is tearing me apart. I don't know what to do. I feel numb, betrayed, very hurt and unwanted. It all happened in a space of about 4 months. 5 months ago my...
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Hi Hoping I can get some clarity for my confusion here, as quite honeslty, I am going round in circles. The history... I met and fell in love with the girl of my dreams about 8 years ago. The relationship was great for about 4 years, and then I started to suspect things were wrong. Now I...
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My boyfriend has had full physical custody for 2 years of his 4 year old daughter. Now before that he had 50/50 custody for one year , the mother of the child has been out the child's life since about the time she was 8 months she has never shown any interest in being involved in this child's...
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text:
Stone Sour Teases With A Brand New Trailer For "Do Me A Favor" [VIDEO]
"Do Me a Favor" is the latest single from Stone Sour and is taken from their new album "House Of Gold & Bones – Part 2″ which is set for a April 9th release date. A brand new trailer for the video can be seen here.
Stone Sour blew it up when they were here for the 32nd annual FMX Birthday Bash with Papa Roach. Stone Sour just keeps gaining momentum and are putting themselves at the top of the rock scene and I couldn't be more stoked.
Don't get me wrong I am a huge Slipknot fan, but i can't hate on Stone Sour they are just a sick band to see live and jam their tunes.
Check out the teaser trailer and let me know if you will be picking up the new album from Stone Sour due out on April 9th.
Subscribe to KFMX FM on


text:
Mumford And Sons Kansas City Tickets
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text:
The mission of the Biology Program at Richland College is to help students develop skills necessary for the continued acquisition and use of scientific information, and to instill an appreciation for the study of life and the process of discovery.
|Location: Sabine Hall, Room SH205
Hours: Monday – Thursday, 8:00 a.m. – 5:30 p.m.
Friday 8:00a.m. – 5:00 p.m.
|Division Phone: 972-238-6248
Division Fax: 972-238-6389
|Executive Dean: Ray Canham, Ph.D.
|Administrative Assistant: Jennifer Crowe
|Administrative Assistant: Laura Reeves


text:
Building and Testing Yelp Mobile
Steven S., Engineering Manager
- Dec 12, 2012
The mobile team at Yelp always strives to bring the best possible experience to your mobile device, but what does it take to accomplish this? For Yelp's iOS app, in addition to tools used by many iOS developers — Xcode for a development environment, Git for version control — we have found other useful tools and libraries to improve our development experience. If you've ever appreciated our app and wondered what goes into its development, we're happy to shed some light on what tools from the iOS development community we make use of, and we even have some of our...


text:
Thomas Lockhart <lockhart(at)alumni(dot)caltech(dot)edu> writes: > create table t1 (x int); > create function foo (out int) returns int as ...; > select foo(x) from t1; > will give two columns for the result. You've *got* to be kidding. To name just one problem with that, where do I put an AS to relabel the extra column? regards, tom lane
Next: From: Tom Lane Date: 2000-06-27 14:23:48 Subject: Re: AW: Big 7.1 open items Previous: From: Thomas Lockhart Date: 2000-06-27 14:05:11 Subject: Re: Makefile for parser


text:
Morphlabs today launched the first all solid-state drive (SSD) private cloud platform, offering performance gains that it said are "pretty massive" while matching the cost of Amazon.
The company's new mCloud Data Center Unit (DCU) has kept its pricing in line with the cost of Amazon or Rackspace by combining compute, networking and storage tech — but with 10-times the input/output operations per second (IOPs) performance, thanks to the SSDs, Morphlabs VP Yoram Heller told Cloudline.
Morphlabs partnered with Dell to deliver the new offering, using its hyperscale server line, PowerEdge C. Dell Executive Director Steve Cumings said in a statement: "The enterprise today requires best-of-breed technologies that deliver unmatched performance and efficiency. Morphlabs has successfully pre-integrated compute, storage and networking into its mCloud solutions."
Heller said that with mCloud, private clouds were nibbling away at the key benefits of public clouds such as Amazon's on cost, while also delivering the benefits of a private cloud, which some organizations needed for things such as privacy compliance.
In addition, with "dynamic scaling" technology, one key advantage to services such as Amazon's was diminished, Heller said. With mCloud's combined compute, network and storage, adding capacity is done by connecting storage to the network, he said.
Heller said this was the next big step in private clouds nibbling away at public services. "That's a lot of what we are going to be seeing in the next three quarters," he said.
mCloud DCU is either delivered by a partner mCloud service provider or in a private rack system. Partner providers outlined by Morphlabs include Pratesis, a private cloud provider based in Jakarta, Indonesia, and Alchemy Communications, a Los Angeles-based provider of private cloud services. Morphlabs is aiming to build out its provider base.
Zane Alsabery, CEO of Alchemy Communications, said: "Alchemy is excited about the prospect of being one of the first data center companies to offer our customers an all-SSD cloud offering."
We've said it before, and it appears again that private cloud options are gaining momentum. Amazon is making it clear its not going to be left out, last week having partnered with Eucalyptus to deliver hybrid cloud that integrates using Amazon Web Services application programming interfaces (APIs).
Have your say: Is 2012 going to be the year of the private cloud? Is SSD and performance at Amazon prices a breakthrough? How about "dynamic scaling" — is it the equivalent of the scalability of services such as Amazon? Where do any of the seeming big deals here fall flat?Go Back to Top. Skip To: Start of Article.


text:
Rival companies DuPont and Monsanto are battling again on the legal stage. This time, DuPont's Pioneer Hi-Bred unit filed a lawsuit against Monsanto over the alleged infringement of two patents for producing more vigorous corn seed.
The two patents, according to the lawsuit, cover a method "of enhancing the vigor of maize seeds" by defoliating the plant before harvesting. While Pioneer claims Monsanto has been using their approach and seeks reimbursement, Monsanto says its production fields do not use DuPont's technology to improve corn and called the suit "baseless" and "without merit" in a statement.
"The filing appears to be another in a serious of frivolous claims initiated by DuPont against our business," Monsanto wrote. "We will defend our business against this latest attack."
Pioneer is aiming to block Monsanto from using patented methods in the future, and alleges Monsanto has been using the patents at its Constantine, Mich., research site. In the suit, Pioneer called the alleged infringement "willful" and "deliberate."
The companies have traded lawsuits since 1999, when DuPont bought Pioneer. Most recently, Monsanto accused DuPont in a 2009 case of infringing patents for seeds that repel the effects of Roundup, an herbicide. The two are also involved in an ongoing court battle regarding a licensing agreement.


text:
Throwback Thursday: Liza Minnelli's Living Room
It's Throwback Thursday! This week's photo from our December 1973 issue features Liza Minnelli's vibrant New York City apartment.
Advertisement - Continue Reading Below
Liza Minnelli's house began as a plain New York apartment, until designer Richard Ohrbach made it into "this super sunny, delicious place where Liza could be lazy." In the living room, various baskets are displayed. "They're where I stash my music and all my personal stuff — things I've forgotten, for now, but someday I'll remember," she said in the 1973 interview.
For images from our archives, outtakes from photoshoots, original snapshots taken by our editors, and more, follow us on Instagram.
A Sculptural Storage Basket >>
Kitchens of the 1960s >>
4 Decades of a Stylish Living Room >>
More from House Beautiful:


text:
If you are new to gardening in Florida, October is a lot like April in the north, minus the spring rains. Fortunately we do start to get some cooler breezes that make working outside in the garden more pleasant.
Vegetable gardening should be going full steam ahead this month. Soil should be amended with compost or other organic matter. Remember that vegetables need six to eight hours of full sun to thrive.
Since our fall can be somewhat dry, remember to provide adequate water as well. It is time to start planting cool season crops such as broccoli, cauliflower, lettuce, carrots, cabbage, and collards. Wait a bit later to plant spinach which needs cool soil to germinate. A great book for Florida gardeners is Vegetable Gardening in Florida by James M. Stephens. You can also access the Florida Vegetable Gardening Guide on the Internet at edis.ifas.ufl.edu/VH021.
If you are looking for more information on veggie gardening, the University of Florida Solutions for Your Life website has lots of information and educational videos at: solutionsforyourlife.ufl.edu. Look under Lawn and Garden category.
Next week: It's time to plant bulbs.
Sources: Carol Suggs and Theresa Badurek, Pinellas County Extension Service. Learn more at askextension.org or pinellascountyextension.org.


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BioAlliance Pharma
Announces Third Positive DSMB Recommendation to Continue Its Phase III Clinical Trial With Livatag® in Primary Liver Cancer
Paris, October 22, 2013 - BioAlliance Pharma SA (Euronext Paris - BIO), an innovative Company dedicated to the development of orphan oncology and to supportive care products, today announced that the International Independent Board of Experts' Data and Safety Monitoring Board (DSMB), in charge of the safety profile of the ReLive Phase III trial, unanimously recommended continuing the study without modification for the third time since the trial's initiation.
The DSMB meets every 6 months and/or after reaching 75 treated patients to evaluate the tolerance of Livatag® and to ensure patient safety. In continuance with its November 2012 and April 2013 recommendations, the DSMB unanimously confirmed its recommendation to continue the study, based on its positive assessment of all safety data of Livatag®.
ReLive is an international, randomized Phase III trial aiming at demonstrating the efficacy of Livatag® on survival in 400 patients with advanced Hepatocellular Carcinoma (primary liver cancer) after failure of intolerance to Sorafenib.
As of the end of September, about 20 centers are opened in France and enrollment is on track with the plan. The European extension of the trial is ongoing as planned with authorizations already obtained in 6 countries (Spain, Italy, Russia, Hungary, Austria and Belgium). The Company plans to expand the trial to the United States in 2014, enabling completion of recruitment in 2015 and data in 2016.
"The follow up of Livatag®'s safety is a major aspect of the ReLive study. The reaffirmed recommendations of the DSMB and its positive evaluation of Livatag®'s safety data are crucial as they strengthen an acceptable safety profile of the product", comments Judith Greciet, CEO of BioAlliance Pharma. "Livatag® is a key drug for the Company with potential sales of several hundreds of millions and addressing patients for whom there is no other therapeutic alternative".
About BioAlliance Pharma
Dedicated to cancer and supportive care treatment with a focus on resistance targeting and orphan products, BioAlliance Pharma conceives and develops innovative products, for specialty markets especially in the hospital setting and for orphan or rare diseases.
Created in 1997 and introduced to the Euronext Paris market in 2005, BioAlliance Pharma's ambition is to become a leading player in these fields by coupling innovation to patient needs. The company's teams have the key competencies required to identify, develop and register drugs in Europe and the USA.
BioAlliance Pharma has developed an advanced product portfolio:
Specialty products
Loramyc®/Oravig® (oropharyngeal candidiasis in immunocompromised patients): Registered in 26 countries (EU, US, Korea), commercialized in Europe and in the US.
Sitavig® (Acyclovir Lauriad®) (labialis herpes): Registered in the US and in 8 European countries, registration status in the other European countries.
Fentanyl Lauriad® (chronic cancer pain): Positive preliminary Phase I results
Orphan Oncology products
Livatag® (Doxorubicin Transdrug™) (primary liver cancer): Phase III on going
Validive® (Clonidine Lauriad®) (mucositis): Phase II on going
AMEP® (invasive melanoma): Phase I on going
For more information, visit the BioAlliance Pharma web site at www.bioalliancepharma.com
This communication expressly or implicitly contains certain forward-looking statements concerning BioAlliance Pharma SA and its business. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of BioAlliance Pharma SA to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. BioAlliance Pharma SA is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.
For a discussion of risks and uncertainties which could cause actual results, financial condition, performance or achievements of BioAlliance Pharma SA to differ from those contained in the forward-looking statements, please refer to the Risk Factors ("Facteurs de Risque") section of the 2012 Reference Document filed with the AMF on April 18, 2013, which is available on the AMF website (http://www.amf-france.org) or on BioAlliance Pharma SA's website ().
BioAlliance Pharma SA
Judith Greciet, CEO
Nicolas Fellmann, CFO firstname.lastname@example.com
Tel.: +33 1 45 58 76 00
Caroline Carmagnol
+33 6 64 18 99 59
Christian Berg
+33 6 31 13 76 20
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