text:
Race against the clock for cancer charity
11:42am Saturday 22nd March 2014
11:42am Saturday 22nd March 2014
FIVE men, 24 hours behind the wheel, but only one CD player – that's the challenge for members of Milford Haven Round Table as they aim to drive through five countries in a day to raise awareness of prostate cancer.
Setting off from Milford Haven on Friday, March 28, the group will take turns to drive a specially sign- written Skoda Superb through England, Scotland, and Northern Ireland, crossing the finish line in Ireland the next day.
A grand finale to a year of fundraising, Round Table chairman Ralph Rees hopes the 'five nations challenge' will clock up some extra cash for cancer charity Prostate Cymru.
So far, more than £8,000 has been raised for the Welsh charity, which promotes awareness of male cancer.
Ralph will be joined by current president Paul Phillips, past chairman Alex Bower, life honorary member Glyn Edwards, and next year's chairman Dan Davies.
"This is an exciting venture and challenge for us, and a fantastic way to not only end my year as chairman but more importantly to raise money for such a worthwhile cause, which will benefit many people in west and south Wales," said Ralph, adding that the biggest challenge may be deciding who picks the music for their epic trip.
Ralph said that, until recently, he hadn't realised that men as young as 45 were at risk of developing prostate cancer.
He added that, through fundraising for Prostate Cymru, he and other Round Table members had learnt a lot about the disease, and the importance of getting checked out, whatever age.
"If you catch it in time, it's curable," he said.
Prostate Cymru is also trying to raise £1.65million for state-of-the-art robotic surgery equipment for Wales, which would lower the risk of complications and improve recovery times for patients.
At present, if patients choose to have 'robotic' surgery, they have to travel to England and pay to it.
"It's wrong that there is currently no opportunity for men to have this treatment in Wales," said Ralph.
To donate to the team's challenge, visit www.justgiving.com/fivenationschallenge, or text MHRT50, followed by the amount you would like to give, to 70070.
© Copyright 2001-2017 Newsquest Media Group


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Heroes, tests scores, literacy and the upcoming Great California Shakeout were among topics taking a turn at the podium at a recent Ramona Unified School District Board meeting.
A newspaper article about World War II Medal of Honor recipient and Pearl Harbor survivor John Finn, who celebrated his 100th birthday this summer, prompted three retired teachers to encourage the board to add the article to required supplemental reading in U.S. history classes.
"In this age of bogus heroes and heroines—rock stars, professional athletes and movie stars—it's essential to this country's well-being never to allow our children to forget what men like John Finn did for their generation, and I can't say enough about this article," said World War II veteran John Bowman, a retired Ramona High School English and U.S. history teacher.
"I think our young people need real heroes, and I think it's an educator's job to find people like Mr. Finn and bring those people to the front so the kids know about these people in our history," said longtime Ramona resident and retired Hanson Lane Elementary School teacher Dotty Cronin, a former RUSD school trustee. "I would use that essay...It's well-written, it's short, it's concise, it's interesting, and I hope that you will use is as part of your curriculum."
"There were a lot of John Finns," said retired auto and English teacher Dr. Andrew Smith, also a longtime Ramona resident and former RUSD trustee.
Smith stressed the importance of what he called "the pivotal, historical moment of five or six years that changed everything" as he encouraged the board to also include portions of Tom Brokaw's "The Greatest Generation" in history classes.
"Nothing was the same after World War II," he said.
Another longtime Ramona resident, Harold Schachter, wrote the article about John Finn that was published in the
Ramona Sentinel
Ramona Sentinel
on July 23 and that, as of this week, had 10,832 "hits" on the
Ramona Sentinel
Ramona Sentinel
Web site.
His voice breaking with emotion, Schachter quoted President Harry S. Truman: "Our debt to the heroic men and valiant women in the service of our country can never be repaid. They have earned our undying gratitude. America will never forget their sacrifices."
Because the subject was discussed during the Open Discussion portion of the school board meeting and the topic was not on the agenda, the state's open meeting law prohibits the trustees from discussing it or taking an action at the meeting. Board President Rodger Dohm thanked the speakers and said he appreciates the patriotism they showed.
RUSD Superintendent Dr. Robert Graeff, whose father was a Pearl Harbor survivor, said he would garner board comments at a later time and perhaps have the high school staff review their request. Graeff said his father died about 18 years ago.
"If he were here, he'd give you all a standing ovation," said Graeff. "So thank you very much for your interest in our country and our education and for the service you all gave America many, many years ago and still give us in leadership and how to live our lives."
A week after the Sept. 17 meeting, Graeff sent a memorandum about the school board presentation with a copy of Schachter's article to the district's secondary social science teachers "as a potential classroom resource."
"As always, teachers have the responsibility to determine if supplementary materials are appropriate for their respective classes, based on the approved course outlines and state standards for each course," Graeff wrote.
Also during the meeting, Assistant Superintendent/Education Services Dr. Cathy Pierce relayed 2009 Adequate Yearly Progress (AYP) and Academic Performance Index (API) results, saying the district has much to celebrate: the district's API increased 9 points, eight schools increased or maintained their API, five schools have APIs of more than 800, James Dukes Elementary is nearing 900, Olive Peirce Middle School crossed the 800 threshold at 813, Future Bound increased 91 points, Mount Woodson increased 32 points, and the district met all AYP components.
The state initially reported that Hanson Elementary did not make its AYP target and thus was in the first year of Program Improvement, but Pierce said after the meeting that the state later said it would not know for sure until November.
AYP, according to the state Department of Education, is a measure of progress for all districts and schools in the state and API measures the academic performance and growth of schools. API is one measure of AYP, with student participation rate in standardized testing, percent proficient and graduation rate also used to determine AYP.
In other business at the meeting:
• Four Ramona High School educators presented a report on the school's "Literacy: More Than Just Reading" plan for the year.
"We believe that reading's more than just books," said RHS Assistant Principal Kathryn Gunderson.
The district's literacy coach is expected to help with the schoolwide program to approach literacy from two main perspectives: English/language arts, "where we are focusing on reading and understanding, how a textbook works, how they're put together, what clues it gives you so that you can better use that textbook to write and then present your information in a coherent, focused way," said teacher Robin Brainard, and 21st century literacy, "to help them to learn to access, to evaluate for validity and then to use the information that's out there that's beyond the textbooks, everything from TV, radio, Internet, then you go to blogs and podcasts and tweets and things that we haven't even thought of yet that they're going to be dealing with in their lives."
In grades 9 and 10, teachers will focus on preparing students to pass the California High School Exit Exam (CAHSEE) and in grades 11 and 12 the focus will shift to preparing the students for college and the work world, said Gunderson.
Teacher Ed Bacorn and Brainard discussed Advancement Via Individual Determination (AVID) classes, Students Transitions at Ramona (STAR), the Odyssey program, the E2020 credit recovery after-school program and advanced placement (AP) classes.
Carolyn Owens, school librarian, focused on 21st century students and learning.
"The U.S. Department of Labor tells us that by the age of 38, they're going to actually have 10 to 14 careers, not jobs" and one of four will be working at a company for less than a year, said Owens. "They have to be mass consumers of data, because data is exploding exponentially."
Today's students are technology users, continued Owens.
"They e-mail, they blog, they instant message," she said. "...When they have a question, they don't think to go to a dictionary or an encyclopedia as maybe we would. They immediately Google."
Students also create information, said Owens. "With things like MySpace, FaceBook, Flicker, Twitter, they actually are part of that four exabytes that are going to be out there."
• Trustees unanimously approved a policy change regarding science instruction. Added to the policy is: "Classroom teachers may provide information to students that supports or questions scientific theories (such as the theory of evolution), but such information must be based in scientific fact, scientific hypothesis or scientific theory. Accordingly, all middle school science teachers and high school science teachers will receive professional development annually designed to assist them in teachiing scientific fact, hypothesis and theory in their respective content areas."
Board members Bob Stoody and Luan Burman Rivera were part of a committee with members of the public and school district who presented the proposed change after Laurence C. Baldaug Jr. of Ramona presented his concerns that the theory of evolution is being taught as a fact and not a theory.
"This was detrimental to the well-being of my 13-year-old daughter who was being told, in effect, by her science textbook, that her Christian beliefs were superstitious nonsense," Baldauf said in an Aug. 24 letter to the board.
Baldauf attended the June board meeting, when he expressed his concerns about theory being taught as fact.
• Trustees approved 2009-10 contracts for the district's nonteaching employees and administrative leadership team. The contracts, as with the 2009-10 contract for teachers, includes no salary increase, but does include pay boosts for what school districts call step and column for additional training and years with the district. The district will continue to provide employees with health benefits at no cost to the employees.
• Two of the board's three student representatives gave reports on the initial weeks of the school year. RHS representative Angelina Uriostegui, a junior, reported about the school's new tardy policy and traffic in front of the school, saying "we hope there could be maybe a way to improve our traffic at Ramona High School in front of the schools there."
Montecito High School representative Graciela Gomez, a senior, talked about the improved API scores for Montecito High and Future Bound, the district's high school independent study program.
Montecito High is offering a new optional sixth-period class that allows students to earn or make up credits, she said.
• In a lively report that included a video of his family reacting to a mock earthquake, Assistant Superintendent/Administrative Services David Ostermann talked about the district's participation in the Great California ShakeOut earthquake drill planned for 10:15 a.m. on Thursday, Oct. 15.

subset: commoncrawl


text:
We began with special prayer at 9:30 a.m. on Mother's Day. We read Psalm 28 as our devotion led by Sunday School Superintendent, Brad Siler.
Several prayer requests were given. We are always a very needy people.
Happy birthday was sung to Pastor Neal. I am not sure how many. May God bless you for all you give as our Shepherd.
Aaron Humbyrd prayed the offertory prayer as he and Daniel Wilson received our Lord's tithes and offerings with LeaAnn Crum at the piano.
Testimonies were given by several people sharing about our good Lord and their mothers. LeaAnn and Erin Crum sang. Pastor Neal read a poem for Mothers and read from Matthew 20 about the mother of James and John. She came worshipping and desiring a thing from Jesus. He said, "What do you want?" She said, grant me that my sons may sit with you in your kingdom. Let us mothers go, worshipping and asking His kingdom for our children. Let us take them to Jesus and stand with them.
Every Mother received a red rose, every Grandmother received a yellow rose and every Great-Grandmother received a pink rose. Peggy Miller and I got all three for we share grandkids and great-grandkids. It is so good to be blessed with your children's children's children.
At 6 pm, Pastor Neal prayed followed by singing. Testimonies were given and prayer requests were shared.
LeaAnn and Erin sang.
Pastor Neal read from Luke 17, Jesus teaching on forgiveness and faith. The apostles said, Lord increase our faith. They realized, as we should, how much we need forgiveness in our lives. If we do not forgive, we cannot be forgiven.
On Saturday, several from church attended Ashton Crum's graduation party. She graduated at 7 pm and left for Panama City, Florida this week.
Sunday, May 20, at 4 pm, the men will cook for the mothers and others.
Come and worship with us. You are welcome.


text:
Originally posted by Jmahoney1979:
Originally posted by socalfan21:
Why would Harbaugh said it wasn't that bad then he is out 6-10 weeks? It doesn't make any sense.
Never take what Harbaugh says about anything at face value, he's trying to keep a tactical advantage.
Its obvious why Harbaugh would say that. He wanted the Lions to think they had to prepare for Morgan.


text:
A composite attempt
I wanted to try some composite work for my son's baseball team. Yes I'm following Joel Grimes look to get a handle on what I like. I did take both pics. The one at the field was shot the other night, my son's pic was taken today in the garage. I played around a bit and came up with this. This isn't the background I want to use in the final copy. I have a pic of the field from the pitchers mound toward home plate with a few bright lights and the backstop fencing in the background.
Anyway, how'd I do? What could I do better? I added some lens flare back in because I already had a bunch in the background photo from my kit lens. It's the only one I have thats wide enough to do what I wanted.
Still need to fix some stuff but like I said this one is quick and dirty to see if I'm on the right path. I deleted some trees behind him that were to busy but missed the branches between his right arm and body, work in progress.
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Not Working + Male Breast Reduction Q&A
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Still Have Puffy Nipples After @ Male Breast Reduction Surgeries, Could This be Excess Gland? (photo)
I got a gyno surgery and was told I did not have any breast gland problem, just exess fat.They did a lipo and removed 250cc and 200 from each.After 3... READ MORE
My Gynecomastia Surgery Was Not Completed on my Right Hand Side.
When I asked the Dr. at pre-op the amount of removal he said, "A lean guy like yourself, we can get pretty much get all of it" Area 1: Lipo... READ MORE
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text:
In Western Australia's Kimberley, the latest round of testing for the muscle wasting disease bovine Johne's (BJD) has returned all negative results.
It's been 14 months since six stations in the Kimberley were placed under investigation after importing bulls from an infected Queensland stud.
Two bulls have tested positive for the disease. However, there has been no further sign of any infection in the herds.
The WA Department of Agriculture's Mia Carbon says the stations will continue to under go testing for the next four years.
"The properties will need to remain under restriction until either all the bulls are found and tested negative or until herd testing results satisfy the chief veterinary officer that the disease is not present on the property.
"Realistically it's unlikely that all imported bulls will be found, so we will need to look to herd testing results," Dr Carbon said.
Dr Carbon said recent bull and herd test results indicated maintaining free zone status remained achievable, subject to ongoing testing and management.
"Herd testing for last year, which involved sampling and testing of nearly 2,500 cattle, has been completed and there has been no evidence of BJD infection in these herds to date," Dr Carbon said.
"To date, 293 bulls have been located and sampled, with 291 bulls testing negative to BJD shedding. Testing on one bull is still underway with results expected in late March."
The president of the Western Australian Pastoralists and Graziers Association, Rob Gillam, says the results are excellent news for the Kimberley.
"Western Australia has got a great advantage of maintaining a free status and there is no doubt about that at all.
"It's fabulous news for the Kimberley and it's come just in the right time as well, given the excellent rise in demand again."
Mr Gillam says the test results would ease the minds of those still under investigation.
"I'm absolutely sure that anyone under the cloud of possible BJD problems will be much happier to hear the news so far.
"They were probably fairly sure that they didn't have a problem, but still had to go through the protocols, and it's now proven that it looks as though BJD hasn't established itself in Western Australia at all."


text:
Harris Teeter Flash Sale today only: Chips Ahoy Thins for 97 cents.
Use the .75/2 coupon from the August 14th SmartSource coupon insert and they are only 22 cents each!
According to their Facebook page, there is a limit of 2.
Make sure it rings up correctly at the register because some customers have posted on their Facebook page that the sale price is not ringing up correctly.
There is no special coupon needed to get the .97 price.


text: Frederick M. Brown, Getty Images A New TV Show Starts Wednesday Night For Country Music Lovers By Mark Tassler October 10, 2012 'Nashville' makes it's debut on ABC, giving you a chance to see inside the music business. Read More Category: Country Music News, Entertainment Tags: country music on TV, Nashville, TV show Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


text: Tomblin introduces bill to regulate aboveground storage tanks By Dave Boucher January 21, 2014 Story Share Bob Wojcieszak West Virginia Governor Earl Ray Tomblin, flanked by U.S. Senator Joe Manchin, WV State Senate President Jeffrey Kessler and Speaker of the WV House of Delegates Tim Miley, announces common sense regulatioin to deal with the chemical storage tanks in the state. Bob Wojcieszak/Daily Mail CHARLESTON, W.Va. - Gov. Earl Tomblin is confident law changes he's proposing will give the state greater oversight of facilities like the one responsible for the recent chemical leak that left 300,000 people without safe tap water.The legislation, called the "West Virginia Source Water Protection Act," also outlines safety procedures for water companies and others in the event of a similar leak in the future."Make no mistake: The discharge of chemicals or other contaminants is unacceptable," Tomblin said. "And neither I, nor anyone standing here with me today, will tolerate it in West Virginia."Sen. Joe Manchin, D-W.Va., state Senate President Jeff Kessler, D-Marshall, and House of Delegates Speaker Tim Miley, D-Harrison, joined Tomblin Monday as he unveiled the proposal.Questions arose about state and federal regulations after the Jan. 9 spill at Freedom Industries, located along the Elk River just north of Charleston.Officials believe as much as 7,500 gallons of crude MCHM leaked from a storage tank at the facility. An unknown amount then seeped through an old concrete wall and into the river, eventually contaminating water at the West Virginia American Water Co. treatment facility about a mile downstream.The Freedom Industries site had only a storm water permit from the state Department of Environmental Protection. Facilities that store chemicals are not as regulated as those that produce them or create emissions, DEP Secretary Randy Huffman said after the press conference.Tomblin's 39-page proposal focuses on a variety of regulatory issues brought to light following the Freedom leak.It creates an aboveground storage tank regulatory program, which would be funded by annual fees collected from storage tank facilities and public water systems.The storage facilities would also pay into a separate "Leaking Industrial Aboveground Storage Tank Response Fund."The amount of the fees would be set by a legislative rule to be written later by the DEP secretary, according to the bill.RegistrationThe fees would be collected as part of a new storage tank registration process.Storage tank owners would have to self-report locations of their facilities to the DEP, as well as provide information about how tanks were built and are being maintained.Owners must also hire a registered professional engineer to inspect and test their facilities and submit a report of the test to the DEP each year. The DEP doesn't have the trained personnel to do such examinations right now, Huffman said."If we had walked around the Freedom tank, we wouldn't have known that the next day it was going to leak just by looking at the tank. There's only so much you can do by just physically walking around," Huffman said."(Registered engineers) testing those facilities is the way that you can get the most certainty in determining the integrity of those tanks."The governor's bill does not specifically mandate the DEP go back and inspect every existing storage tank, Huffman said. Both Tomblin and Huffman said they had confidence in the self-reporting mechanism outlined in the plan."The self-reporting actually does work because falsifying this will have criminal penalties associated with it," Huffman said. The bill also outlines procedures storage facilities and water companies need in order to prepare for and respond to a spill.A company must - in some way - show it has the means to cover the costs of a spill before it can register with the DEP, according to the bill.That proof could be anything from a surety bond to demonstrating the company has enough assets to "undertake reasonable corrective action" if there is a spill.The company must also submit a "spill prevention response plan" for each of its storage tanks.The proposal requires the plans be updated every three years. A site must create a new plan at once if there are significant changes made to the facility, the current plan fails or a variety of other circumstances occur.The spill prevention response plans must include a description of the facility and what goes on there; the material safety data sheets for any materials stored there; emergency plans, like secondary containment barriers, in place at the site; and countermeasures that can be taken if there is a spill.The information will be provided to the DEP and local emergency response officials and public water systems located within 25 miles of the chemical storage sites. The general public will also have access to information about the facilities and what they store, Tomblin said.More informationFacilities like Freedom's site on the Elk River already had to file chemical inventories, known as Tier II reports, with the state. While these reports offer little information about a storage site - if it's near a water treatment plant, for example - they do provide information about the chemicals stored there.Because the crude MCHM stored at the Freedom Industries site did not meet a strict definition of "extremely hazardous" as applicable to these reports, the Freedom report fell into a larger pool with roughly 9,500 other facilities.That includes many oil and gas rigs along with at least 500 gas stations, a state spokesman recently told the Daily Mail.A local emergency response official recently told Charleston Gazette such reports can fall by the wayside when creating plans for responding to an emergency.Tomblin said the bill does not duplicate any current state or federal regulations."What it will do is allow the DEP to work with our public health officials and the DHHR to make sure that our zones of critical concern near our precious waterways remain safe," Tomblin said.A "zone of critical concern" falls under the part of the bill that requires more work from public water systems.In addition to paying an annual fee and the spill prevention response plan, systems considered to fall in these zones will also have to submit a "source water protection plan" to the DEP.That plan must include how the water system will respond if its water supply is contaminated, information on alternative water sources, what the system will do to protect its water source, and a communication plan for how the company will notify the public in the event water is contaminated.The bill outlines several other specific requirements for both public water systems and storage facilities regarding providing information about responding to an emergency and preparing for such an event.It also includes potential civil and criminal penalties for violations of the bill.Many of the specifics definitions, fee amounts and other details are left up to the DEP secretary to create in legislative rules.Pledging supportManchin applauded the state's effort to create legislative changes in response to the spill. Sen. Jay Rockefeller, D-W.Va., issued a statement lauding the efforts of state leaders as well.Manchin and Rockefeller have co-sponsored a federal bill, the Chemical Safety and Drinking Water Protection Act, that also addresses regulations of facilities and increasing emergency preparedness.Leaders in the Legislature pledged to work with the governor on passing the measure.Saying the state must never let something like this happen again, Kessler pointed to a bill already introduced in the state Senate that is similar in focus to the governor's measure."Regulation, we hear from time to time, folks don't want regulation," Kessler said. "Government keep their hands off; government stay away."I'm here to tell you that no person, no industry, no company will be able to go without knowing that there is somebody looking over their shoulder," he said.Miley echoed those statements.He said some believe there's a negative stigma associated with the idea of regulation."Often times when someone mentions regulating something that's in the business world, everyone wants to fear monger and say that it's going to cost jobs," Miley said."But I'd rather save lives than be worried about saving a few jobs," he said. "Saving lives always has to come first, saving jobs second."Miley also applauded what he considered a measured and methodical response by Tomblin in creating the legislation, and pledged to cooperate with House Minority Leader Tim Armstead, R-Kanawha, on passing the bill.Tomblin said he expects the bill to be introduced in both the House and Senate Tuesday.Contact writer Dave Boucher at 304-348-4843 or email@example.com. Follow him at www.Twitter.com/Dave_Boucher1. Story Share Story Share Trending Now 1 DHHR: WV medical marijuana law will need $2 million in upfront costs 2 Gazette editorial: Is it time for health care for all yet? 3 Vintage West Virginia: Putnam Village 4 Malfunctioning aircraft lands safely at Yeager Airport 5 WV Gov. Justice appoints Foster's replacement to House Neediest Cases Appeal raises more than $102,000 Previous Story WV water utility objects to Freedom Industries bankruptcy motions Next Story


text:
Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2015 by Indiana University.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Indiana University
Novo Nordisk A/S
Information provided by (Responsible Party):
Indiana University
ClinicalTrials.gov Identifier:
First received: November 1, 2010
Last updated: April 8, 2015
Last verified: April 2015
|Tracking Information
|First Received Date ICMJE
|November 1, 2010
|Last Updated Date
|April 8, 2015
|Start Date ICMJE
|January 2012
|Estimated Primary Completion Date
|December 2015 (Final data collection date for primary outcome measure)
|Current Primary Outcome Measures ICMJE
|myocardial glucose uptake [ Time Frame: 3 months ]
PET measurements of myocardial glucose uptake will be done after 3 months of exposure to liraglutide, insulin detemir, or liraglutide plus insulin detemir
|Original Primary Outcome Measures ICMJE
|Same as current
|Change History
|Complete list of historical versions of study NCT01232946 on ClinicalTrials.gov Archive Site
|Current Secondary Outcome Measures ICMJE
|Not Provided
|Original Secondary Outcome Measures ICMJE
|Not Provided
|Current Other Outcome Measures ICMJE
|Not Provided
|Original Other Outcome Measures ICMJE
|Not Provided
|Descriptive Information
|Brief Title ICMJE
|Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
|Official Title ICMJE
|Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
|Brief Summary
|The investigators will test the hypothesis that effects of liraglutide plus insulin detemir on myocardial fuel selection will be greater than the effects of either agent alone. 27 Type 2 diabetic subjects (HbA1c 7.5 - 9.5%) currently treated with diet and exercise alone or with oral antidiabetic agents will be randomly assigned to one of three treatment groups: insulin detemir, liraglutide, or liraglutide plus detemir (9 subjects per group). All subjects will undergo an initial standardization of background treatment to metformin 2000 mg per day, followed by randomized assignment to 3 months' treatment with liraglutide 1.8 mg/day (once daily each morning, tapering up according to label instructions) and/or detemir (administered twice daily, initially at 10 units per day then titrated to achieve fasting morning glucose readings below 130 mg/dL). PET measurements of myocardial fuel selection will take place at the end of this treatment period, under fasting conditions in the morning following that day's treatment injection(s).
|Detailed Description
|Not Provided
|Study Type ICMJE
|Study Phase
|Not Provided
|Study Design ICMJE
|Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
|Condition ICMJE
|Type 2 Diabetes
|Intervention ICMJE
|Study Arms
|Publications *
|Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
|Recruitment Information
|Recruitment Status ICMJE
|Unknown status
|Estimated Enrollment ICMJE
|Estimated Completion Date
|December 2015
|Estimated Primary Completion Date
|December 2015 (Final data collection date for primary outcome measure)
|Eligibility Criteria ICMJE
Inclusion Criteria:
Exclusion Criteria:
|18 Years to 50 Years (Adult)
|Accepts Healthy Volunteers
|Contacts ICMJE
|Contact information is only displayed when the study is recruiting subjects
|Listed Location Countries ICMJE
|United States
|Removed Location Countries
|Administrative Information
|NCT Number ICMJE
|Other Study ID Numbers ICMJE
|Has Data Monitoring Committee
|U.S. FDA-regulated Product
|Not Provided
|IPD Sharing Statement
|Not Provided
|Responsible Party
|Indiana University
|Study Sponsor ICMJE
|Indiana University
|Collaborators ICMJE
|Novo Nordisk A/S
|Investigators ICMJE
|PRS Account
|Indiana University
|Verification Date
|April 2015
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP


text:
Disclaimer: While this post has a sponsor, all facts and opinions expressed are those of the research article I am presenting as well as my own, none of which have been influenced in any way, shape, or form by the sponsor. I do not accept suggestions or recommendations from the sponsor for any story ideas or post content.
Great wine quality is something that every winemaker strives for. I don't know anyone whose goal is to make the world's worst bottle of wine, so determining what makes a quality wine, or more specifically, how consumers perceive wine quality is important for every winery to grasp. There has been a lot of research on extrinsic qualities of wine and how those relate to overall perceived wine quality, including bottle size, bottle weight, label design, grape variety, region of origin, numbers of awards, et cetera. However, not as much is known about intrinsic qualities of wine such as aroma and taste, and how specific qualities or combinations of qualities are perceived by consumers to represent a high or low quality wine.
With intrinsic qualities, there is likely to be a wider range of variability in terms of how quality is perceived, depending upon many factors including personal level of wine expertise, experience, and culture. In fact, in food studies, it has been shown that consumer culture as well as consumer familiarity with a product significantly influences perception of flavor and overall quality in the food product of study. Though these types of studies have been frequently examined in food products, studies focused on wine are extremely limited. Those few studies related to this topic have basically looked at the concept of "product familiarity" and how experience and familiarity with a particular style of wine influences the perception of wine quality and preferences. Other studies have found that novice consumers tend to
relate quality with their personal experiences, which leads to a large variability in quality perception from consumer to consumer. On the other hand, wine experts armed with significantly more knowledge about a particular wine varietal or winemaking style base their quality "scores" on less subjective characteristics resulting in less variability from expert to expert.
The study presented today aimed to add to the limited knowledge regarding the influence of intrinsic characteristics of wine quality, specifically examining whether or not consumer culture as well as their level of expertise leads to increased (or decreased) quality perception.
After a small pilot experiment to find wines that were relatively variable in terms of their perceived quality, six Spanish wines from La Rioja and six French wines from Côtes du Rhône were selected for the study.
Participants were recruited via ads in public areas, online, on the radio, and in the newspaper. Participants were required to be regular consumers of red wine (i.e. drinking red wine at least once every 2 weeks), have no experience in the wine industry, lives in La Rioja or Avignon for at least 10 years, and be at least 18 years old (legal drinking age).
- Spanish consumer participant demographics:
- 51.8% men, 48.2% women
- Ages 19-67, median 39.5
- 56 participants total
- French consumer participant demographics:
- 48.1% men, 51.9% women
- Ages 19-67, median 42.5
- 52 participants total
Expert participants were eligible to participate if they were established winemakers, wine researchers, wine professionals, had many years' experience with wine, or were graduate students in Viticulture and Enology programs.
- Spanish wine expert demographics:
- 51% men, 49% women
- Ages 24-56 years, median 35
- 59 experts total
- French wine expert demographics:
- 67% men, 33% women
- Ages 22-72, median 45
- 60 experts total
All participants were presented with a series of 6 wine samples at one blind tasting session and were asked to rate them in terms of their quality: very low quality; low quality; high quality; or very high quality. Participants were allowed to place as many wines in one particular quality category that they desired. The tasting session was in a controlled research tasting facility and lasted about 20 minutes for each participant.
- Quality perception was found to be significantly different for Spanish consumers only, while there were no differences in quality perception between Spanish experts, or either French test group.
- Spanish consumers frequently rated Spanish wines from La Rioja as "very high quality" significantly more often than French wines.
- Aromas of wines in this experiment were found to be clustered into 3 different groups for all of the participants.
- Cluster 1: 5 Spanish wines were found in this cluster, and were characterized by wood, leather, and toasted bread by the Spanish participants, and by smoky, fresh wood, cardboard, and wet cloth by the French participants.
- These characteristics were seen as positive for both Spanish and French consumers while they did not seem to be important to French experts and were seen as negative for Spanish experts.
- Cluster 2: 3 of the French wines were found in this cluster, and were characterized by red fruits and alcohol for both Spanish and French consumers, while Spanish consumers also noted aromas of apricot or fresh, and French consumers noted solvent-like aromas.
- These characteristics were seen as negative for both Spanish and French consumers, while they were seen as positive for both Spanish and French wine experts.
- Cluster 3: One Spanish and one French wine were found in this cluster, and were characterized by animal and vegetal aromas for the Spanish consumers and blackcurrant bud for the French consumers.
- This cluster received the lowest quality score from both Spanish and French consumers, while it received the second lowest quality score from Spanish and French wine experts.
- Cluster 1: 5 Spanish wines were found in this cluster, and were characterized by wood, leather, and toasted bread by the Spanish participants, and by smoky, fresh wood, cardboard, and wet cloth by the French participants.
- Aromas of wines in this experiment were found to be clustered into 3 different groups for all of the participants.
- Higher quality scores were associated with aromas of wood-related terms for both Spanish and French consumers.
- Lower quality scores were associated with aromas of animal and sulfur for Spanish consumers.
- Higher quality scores were associated with aromas of vanilla and red fruits for both Spanish and French wine experts.
- Lower quality scores were associated with aromas of vegetal, blackcurrent bud, animal, and musk for both Spanish and French wine experts.
- Dried fruits were negatively associated with quality for Spanish wine experts.
- The only characteristic that was significantly correlated for both Spanish and French participants was for astringency. All other flavors were highly variable between all of the groups in terms of perception of quality.
- Higher quality scores were associated with the "balance" characteristic for Spanish wine experts, while Spanish consumers preferred wines with lower astringency.
- Higher quality scores were associated with increased complexity for both Spanish consumers and Spanish wine experts.
- Lower quality scores were associated with increased "bitterness" for French wine experts, while higher quality scores were associated with increased "sweetness" for French wine consumers.
Overall, the results of this study showed that perceived wine quality is dependent upon experience, as was evident by the large variations in perceived quality by "regular" versus expert wine drinkers. Breaking it down further, the results showed that there were no differences in perceived wine quality by wine experts from different cultures. In other words, both Spanish and French wine experts were, on average, in agreement about the quality of the wines in this experiment, and rated them more along enological/winemaking, grape growing, and other technical characteristics than any other factor.
On the other hand, the results of this study indicated that wine consumers tended to associate wine quality with their own personal experiences with wine, leading to more subjective quality scores comparedwith the more objective scores assigned by the wine experts. Simply put, experts rely on their vast wine technical knowledge to make quality assessments, while the wine consumer has only his or her own limited past experiences to assign quality judgments.
Digging a little deeper, the results of this study indicated that Spanish consumers preferred their own local La Rioja wines over French wines, though this culture preference was NOT found when the focus was on French consumers. In other words, the Spanish consumers ended up scoring La Rioja wines a higher quality than French wines from Côtes du Rhône.
Why is it that Spanish consumers scored La Rioja wines higher, while French consumers did not score wines from Côtes du Rhône higher?
The authors of this study speculated that the reason why Spanish consumers ended up scoring La Rioja wines better than Côtes du Rhône wines because of the fact that they were simply used to La Rioja as their drink of choice, and subconsciously associate quality with wines that share similar characteristics as wines La Rioja. Well, if that were the case, then wouldn't it be the same for French consumers? Shouldn't the French consumers score wines from Côtes du Rhône higher than wines from La Rioja? The results of this study indicated that this was NOT, in fact, true, so why would there be this difference between Spanish and French wine consumers?
The difference in perceived quality of wines for French and Spanish wine consumers, according to the authors, may have something to do with what they drink in the comfort of their own homes normally. Surveys held concurrently with this study found that out of 93 consumers from La Rioja, 73% of them primarily drank wines from La Rioja. It makes sense to me then that if the majority of folks from La Rioja drink almost exclusively wines from La Rioja, they would be more likely to associate higher quality with those wines that share similar organoleptic characteristics as La Rioja wines. In terms of the French consumers, however, a survey held concurrently with this study found that out of 95 consumers from the Côtes du Rhône region, 74% of them are used to drinking and purchasing Italian wines, and NOT winesfrom the Côtes du Rhône region. Therefore, it makes sense to me that the French consumers did not show cultural preferences for the Côtes du Rhône wines during the blind tasting, since the aromas and flavors of Côtes du Rhône wines are out of their realm of experience.
Finally, in terms of the aroma of the wines versus the tastes, flavors, and other mouthfeel characteristics, it was interesting to see that aroma was significantly more important to determining perceived wine quality than any other characteristic. The only taste/flavor/mouthfeel characteristic that seemed to matter in terms of assigning wine quality was astringency. In summary, the results indicate that aromatics seemed to play a more important role in the assignment of wine quality, which taste/flavor seemed to play a more secondary role.
Overall, I thought this was a pretty interesting experiment. In particular, what I thought was most interesting that often times, the regular wine consumers' perception of quality was opposite of what the wine experts classified as a quality wine. What does this mean for using expert opinions and recommendations for choosing wines at the wine shop? Of course, this is just one experiment using one small subset of the wine consumer market so my next thoughts are pure speculation, however, if anything, this study reinforces the idea for me that there should be wine experts representing a range of different taste profiles. You see a lot of experts and blog that have similar Robert Parker-esque preferences, though where are the voices for different flavor profiles? Where is the sweet wine expert, etc?
The results of this small study indicate that perhaps we may want to broaden ourselves when it comes to writing about or recommending certain wines. We all have different tastes, different palates, and most of us aren't going to become wine experts, so where is the voice for the average wine consumer? What's quality to the experts may not be quality to a big chunk of the consumer pie, so perhaps there needs to be a better way to market to this potentially large population of consumers in order to further increase wine consumption throughout the world.
What do you all this about this study and this topic in general? Please feel free to share your experience, thoughts, questions, comments, or whatever else you'd like to discuss related to this topic.
Source: Sáenz-Navajas, M-P, Ballester, J., Pêcher, C., Peyron, D., and Valentine, D. 2013. Sensory drivers of intrinsic quality of red wines: Effect of culture and level of expertise. Food Research International 54: 1506-1518.


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Anytime Fitness — which describes itself as the fastest-growing fitness club franchise in the world — is adding another Albuquerque location.
The new gym will go in near Cost Plus at Menaul and Carlisle, absorbing two adjacent suites in the American Square shopping center.
Construction on the 4,800-square-foot site should begin soon and the gym could open by late August, according to franchisee Ira Herman, who is opening the gym with his wife, Eshita.
Anytime Fitness will have the traditional gym trappings — including cardio and weight equipment — as well as a fitness room with a video screen and a host of virtual exercise classes that members can access when they want.
"It gives us a lot of flexibility," Herman said.
Anytime Fitness is a 24-hour gym that clients can enter at any time using an electronic key. There are three existing locations in Albuquerque and a total of 2,400 worldwide.


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Angilee Shah
Digital Editor, Global Nation
I'm the digital editor for Global Nation, PRI's coverage of immigration in the US. I started at PRI as the social media manager, helping integrate engagement into our editorial process. I've spent most of my career writing long pieces (for magazines) and short posts (on Twitter) about politics and culture. I've reported from across Asia, including China, Thailand, Indonesia and Sri Lanka, and on diverse cultures across the US, from Southern California to Minneapolis, where I am currently based.
In my non-digital life, I am the co-editor of Chinese Characters (UC Press, 2012) and a consulting editor to the Journal of Asian Studies.


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Washington, DC—Nevada Senator Harry Reid made the following remarks on the Senate floor this afternoon at the opening of the 112th Congress. Below are his remarks as prepared for delivery:
"Happy new year, and happy new year to all my colleagues – those returning to the Senate and those taking office today for the first time.
"I am honored, humbled and will forever be grateful that the people of Nevada have entrusted me with another term as their Senator. I will continue working hard to create jobs for the people of my state and get our economy back on track.
"I am also grateful for the continued support and confidence of my caucus, which has again given me the honor of serving as its Leader. Neither title – Senator and Majority Leader – is a responsibility I take lightly, or for granted.
"They say you can never step in the same river twice. New water flows in, replacing the old and continually renewing the river. The Senate is the same.
"This body never stops changing. Every two years – and occasionally more frequently – new Senators take their seats in this chamber. They join the Senate family and this ever-evolving team of 100 tasked with moving the country forward.
"But our fundamental responsibilities and traditions anchor us in that river. Our respect and reverence for the people we serve and this institution never wavers or changes.
"According to academics, pundits, and congress-watchers, the 111th Congress, the last Congress, was the most productive in American history. But many challenges and opportunities still lie before the new Congress that starts today. We have to do even more to help middle-class families, to create jobs, to hasten our energy independence, to improve our children's education and to fix our broken immigration system.
"We also have to make sure the Senate can operate in a way that allows the people's elected legislators to legislate. So we will soon debate some reforms to Senate procedure – reforms proposed not for the sake of change itself, or for partisan gain, but because the current system has been abused, and abused gratuitously. The filibuster in particular has been abused in truly unprecedented fashion.
"There are strong passions on both sides of this debate. There are nearly as many opinions about what to do about these abuses as there are Senators. But let us start the conversation with some facts:
"There were about as many filibusters in the last two Congresses as there were in the first six-and-a-half decades that the cloture rules existed.
"There were nearly as many filibusters in just the last two years as there were in the 1920s, 1930s, 1940s, 1950s, 1960s, and half of the 1970s combined.
"In the entire 19th century, the Senate saw fewer than a dozen filibusters. Now we see that many in a month.
"Many of those recent filibusters were terribly unproductive. Many of them prevented us from even holding a debate on a bill, let alone an up-or-down vote. And after we wasted hour after hour and day after day, many of those bills passed and many of those nominees were confirmed overwhelmingly or unanimously.
"I have been forced to use my right as Majority Leader to fill the amendment tree more than I would have liked to for a simple reason: Rather than offer amendments to improve legislation or compromise for the greater good – as members of this body have done for generations – the current minority has offered amendments simply to waste time, to delay us from proceeding to a bill or to score political points.
"Finally, these rules are central to the Senate, but they are not sacrosanct. Senate procedure and cloture rules have changed since this institution was founded, when necessary and after serious consideration. Those decisions have never been made without great deliberation, and no future changes should be made any differently.
"The recent abuses we've seen have hurt the Senate and they hurt the country. They hurt our economic recovery and they hurt middle-class families. They hurt the institutions that lead and shape America because they keep public servants and judges from their posts for no reason other than mere partisanship.
"Even Chief Justice Roberts criticized the Senate a few days ago for how few judges we confirm, and how slowly we do so. His criticism and concern are well founded. I hope all my colleagues consider the Chief Justice's warning and what it means for the pursuit of justice in this country.
"This is the bottom line: We may not agree yet on how to fix the problem – but no one can credibly claim problems don't exist. No one who has watched this body operate since the current minority took office can say it functions just fine. That would be dishonest. No one can deny that the filibuster has been used for purely political reasons – reasons far beyond those for which this protection was invented and intended.
"So in the coming days, let's come together to find a solution. That's why we're here. United States Senators must solve problems, not create them.
"The last time Congress convened without Robert Byrd as a Member, Harry Truman was President. Forty-two of our 100 Senators hadn't even been born yet.
"No one knew the Constitution better than Robert Byrd, and no one revered it more. He taught many of us many things. Among them, he taught me to carry the Constitution with me every day. I do. I always have this copy of our founding document in my pocket, signed by Senator Byrd, one of its most fervent defenders.
"He loved the Constitution not just because of what is written there, but how those words werewritten – how it all came together. He knew that our Constitution was created through compromise. At a moment of particular partisan strife 15 years ago, Senator Byrd came to this floor and said the following:
"'I hope that we will all take a look at ourselves on both sides of this aisle and understand also that we must work together in harmony and with mutual respect for one another. This very charter of government under which we live was created in a spirit of compromise and mutual concession. And it is only in that spirit that a continuance of this charter of government can be prolonged and sustained.'
"Our friends in the House have decided to begin their daily business by reading the Constitution. In these first few minutes of the new Senate session, I think we should reflect on Senator Byrd's wise reminder of its history.
"And like the Constitution, the agreement that established two separate and different houses in the legislative branch was itself a compromise. As much as ever before, our two branches need to find common ground if we are going to be productive for the people we serve together.
"'In that same speech 15 years ago, Senator Byrd reminded us that 'the welfare of the country is more dear than the mere victory of party.' I think we would do well to heed those words as we debate and decide how to best serve the nation and its people in this new year.
"Senators come and go, majorities and minorities rotate like a rolling wheel, and records of service are written and rewritten. The only constant in our democracy is change. Sixteen Senators who were here just weeks ago have moved on, and 16 new ones now take their seats. Laws that governed this nation and rules that govern this body continue to evolve carefully and by necessity.
"The most important change we can make in the 112th Congress is to work better and more closely as teammates, not as opponents – as partners, not as partisans – to fulfill our Constitutional responsibility to pursue a more perfect union, establish justice, insure domestic tranquility, provide for the common defense, promote the general welfare, and secure the blessings of liberty to ourselves and our posterity."


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Meetings seek input on how to plan for growth
Planners believe James- town could see a population growth of about 7,500 to a total population of nearly 23,000 in 25 years. They want to hear from residents how to manage and plan for that growth, according to Marty Shukert, principal planner for RDG Planning and Design, the firm preparing the Land Use and Transportation Plan for the community.
The Jamestown population has been steady in the 15,000s since the 1960s. Shukert said currently planned industrial projects could prompt population growth. These projects include the Dakota Spirit AgEnergy ethanol plant, CHS nitrogen fertilizer plant and the eNugget iron smelting plant, which are all in some stage of construction or planning at this time.
Shukert's data projected three levels of possible growth for consideration:
*A 1 percent population growth for the next 10 years followed by a 0.5 percent population growth per year for the following 15 years would give Jamestown a population of about 17,300 by 2025 and nearly 19,000 by 2040. This is considered a slow rate of growth.
*A moderate growth rate of 1.5 percent for the first 10 years and 0.75 percent for the next 15 years would result in a population of more than 18,500 by 2025 and nearly 21,000 by 2040.
*An aggressive growth rate of 2 percent for 10 years and 1 percent for the next 15 years would result in a population of about 19,000 by 2025 and nearly 23,000 by 2040.
"The conversations with the JSDC (Jamestown/Stutsman Development Corp.) suggest a population increase of about 3,000 is reasonable in 10 years given the industrial growth," Shukert said. "For planning purposes, the middle-growth plan feels like the reasonable model."
Shukert said this would mean Jamestown would have to average about 50 new housing units per year for the next 25 years. Jamestown saw a net increase of 13 housing units or 1.3 per year on average between the years 2000 and 2010.
"This doesn't mean you would have people living in the street," he said. "But it is more difficult to attract people if there isn't adequate housing."
The additional housing will require additional land to be developed for residential and commercial use. Shukert estimates that about 626 acres of residential development and 118 acres of commercial development will be necessary over the 25-year life of the plan.
Shukert is conducting meetings today and Thursday in Jamestown to get public input as he prepares the LUTP. The workshops run from 11 a.m. to 1 p.m. and from 4 p.m. to 6 p.m. today at Jamestown City Hall and are intended for the public to talk with the planners. Shukert will make a presentation of the findings of the previous meeting at 4 p.m. Thursday in the Exchequer Room of the Jamestown Civic Center. For those who cannot comment in person, a survey is available at www.rdgusa.com/jamestown.
"This trip begins the real planning," he said. "We start putting ideas on paper and visualize how the city may look years in the future."
This month's meetings, called "studios" by Shukert, looks at the big picture of development in the area.
"We are taking the macro approach to issues at this time," he said. "We are looking at the overall growth and the amount of land needed for development. Later studios have a greater level of detail."
Shukert said the LUTP is intended to develop a plan of where this development will occur and the best infrastructure for transportation in Jamestown. He also wants it to be the product of local residents' input.
"This isn't a process of a bunch of engineers and planners going off and waving our hands and telling you what you need," he said. "We want this to be a plan that meets the needs of the public."
City Engineer Reed Schwartzkopf said more involvement by the public would help make the plan more valuable as a planning tool.
"I'd love to see the community come out in droves," he said. "In my mind, for this to be successful, it has to be the city residents' plan."
Shukert said future planning studios look at the planning in more detail. If a high degree of interest is shown in a single topic, separate meetings will be held.
Sun reporter Keith Norman can be reached at 701-952-8452 or by email at email@example.com


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Calculating the Spread and the Fed
The agency mREIT sector's malaise has hit shares of said "Portfolio Guru, LLC shareholding Armour Residential REIT (ARR), whose shares have fallen 7.0% in 2013 vs. the S&P 500's 16.9% gain.
Agency mREITs borrow money to buy mortgage-backed securities guaranteed by FNMA, GNMA, or FHLMC. The difference between their borrowing cost (in the repo market) and the interest rate earned on MBS holdings is their "spread." That spread multiplied by the leverage ratio is their profit margin. mREITs are leveraged bond funds dressed up as common stocks, and have to pay out 90% of what they earn to maintain REIT status (and pay no corporate taxes.)...527 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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It was definitely a WTF moment when I found out some time ago that Jesse James was Sandra Bullock's husband. One of these things is not like the other, indeed. 😉
Sunday night's premiere of Jesse James Is A Dead Man on Spike TV gave the channel its most viewers and highest rating among men 18-49 for a unscripted series premiere. The program was viewed by 888,000 men 18-49 and two million people overall.
via Broadcasting & Cable.


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Molly Stark Kids Change The Words To Dierks Bentley's "5150" To Sing About Their School In Bennington, Vermont – Reading, Writing, and Rhyming [AUDIO-VIDEO]
What a group! What a school! (I get yelled at with these articles for using the exclamation point too many times, but I don't care. What a FANTASTIC experience going to Molly Stark Elementary School in Bennington!!!!!!!!!! (So there!!!!!!!)


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You can increase the range from 250 miles to 300, or from 300 to 350 -- but that alone means very little for the road trip if the recharge time is long. You basically run into a metaphorical wall despite very high costs -- if the charging times are long.
My argument is this: Once we have hit a certain sweet-spot for range in terms of an electric car -- I argue that it is somewhere between 200 and 300 miles -- the competitive frontier for the automobile manufacturers will move from the range of the batteries in the car, to the charging network.
Imagine a world in which your electric car could get 150 miles of range in five minutes. Or even 10 minutes. If these charging stations were so readily available so as to not cause you to worry about finding them you would not need a bigger battery and it would be "game over" for traditional gasoline/diesel automobiles.
If you are a car company, investing more in a 200- to 300-mile electric car's battery -- even just to cost-reduce it -- will ultimately get you nowhere in terms of the competitive matrix. The competitive frontier will have moved from the car to the charging network.
Even in this 200- to 300-mile range electric car scenario -- today's Tesla -- the vast majority of people don't need any radically fast charging on most days. You charge at home overnight, at work during the day and perhaps at some public parking garage once a week. Seeing as you tend to drive fewer than 200 miles per day, that's all you need.
But we all know that the unexpected happens: emergencies, detours, change of plans or perhaps you simply forgot to charge on a few occasions. It's like insurance: You don't need it on most days -- perhaps even weeks or months. But you still need insurance for the outlier events.
In other words, even if it costs more to charge quickly, having the fast-charge option will be a strong competitive weapon. On most days you will charge for a very low price using slow-charging (240 or 110 volts, AC), but on the few moments you really need it on a road trip or in an emergency you'd be willing to pay a higher price for the electricity being fed at 440 volts DC.


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There is growing concern that the number of uninsured motorists on the roads may increase after the UK's biggest car insurer said it is changing the level of cover it provides.
Norwich Union, which insures one car in every seven, is removing the provision called "driving other cars" (DOC) that allows motorists to drive cars belonging to other people if they have the owner's permission.
It says the clause is abused, enabling drivers to buy cover for a small car and then use high performance vehicles belonging to friends and family that they would not normally be able to get insurance for.
But others in the industry say the change could lead to more uninsured drivers on the road because people will continue to use vehicles they do not own, either because they have to, or because they do not understand the change.
Norwich Union's Head of Underwriting, Lawrence Loughnane, told BBC Radio 4's Money Box it was acting partly on feedback from the police.
"When they try to enforce the issue of uninsured driving, time and time again [DOC] makes it virtually impossible for them to do anything at the roadside," he said.
'Huge confusion'
"I can see a lot more people on the road driving unintentionally uninsured...
"Some people will have [insurance] and some people won't. There will be huge confusion," he said.
Insurers Cornhill and More Than told the programme they are renewing their policies in light of Norwich Union's decision.
But Direct Line, Privilege, Churchill, Tesco and Esure say they will keep DOC.
Taken ill
Esure spokesman Adrian Webb said honest customers need it.
"There are scenarios where people have to drive other people's cars with their permission," he said.
"They would be taking to the road uninsured without it."
Norwich Union admits the move will save money but said it will be passed on to customers in reduced premiums.
The change will affect everyone applying for a new policy or renewing an old one with Norwich Union Direct from the New Year.
However it only affects motorists buying direct, not going through a broker.
BBC Radio 4's Money Box was broadcast on Saturday, 15 October, 2005, at 1204 BST.
The programme was repeated on Sunday, 16 October, 2005, at 2102 BST.
Download or subscribe to this programme's podcast


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BP Comment Quick Links
|Strength of Schedule Report
April 10, 2012
Tater Trot Tracker
Trot Times for April 9
The allure of Opening Week is finally gone. While some teams are still celebrating (or awaiting) their home openers, others are already back to midseason form. In Houston, 17,095 paid to see the hometown boys beat the Braves. In Oakland, the stellar Royals/A's matchup only brought out 10,054 paid attendees. One of those is bound to change on Tuesday, as the Astros plan to hold their first throwback game of the year. In honor of their 50th anniversary, the team will be wearing old Houston Colt .45s jerseys, smoking gun and all.
If that doesn't bring folks out to Minute Maid Park, I don't know what will. In the meantime, let's get to the trots!
Home Run of the Day: Pablo Sandoval, San Francisco Giants - 22.54 seconds [video]
Slowest Trot: Bryan LaHair, Chicago Cubs - 25.12 seconds [video]
Quickest Trot: Alejandro De Aza, Chicago White Sox - 17.95 seconds [video]
At 18.29 seconds, Boston's Dustin Pedroia wasn't much behind De Aza for the quickest trot. Omar Infante and Darwin Barney had pretty nice trots of their own.
All of Today's Trots Bryan LaHair......25.12 Matt Wieters......21.67 Rickie Weeks......23.9 Nelson Cruz.......21.55* Jose Lopez........23.31 Yadier Molina.....21.17 Matt Holliday.....22.93 Austin Kearns.....20.85 Mitch Moreland....22.9 Kirk Nieuwenhuis..20.68 Josh Willingham...22.56 Omar Infante #1...20.44 Pablo Sandoval....22.54 Josh Hamilton.....20.03 Ian Kinsler.......22.42* Darwin Barney.....19.33 AJ Pierzynski.....22.12 Omar Infante #2...19.21 David Freese......21.99 Dustin Pedroia....18.29 Justin Maxwell....21.8 Alejandro De Aza..17.95 Andruw Jones......21.74
Click here for the ongoing 2012 Tater Trot Tracker Leaderboard. You can also follow @TaterTrotTrkr on Twitter for more up-to-the-minute trot times.
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Christmas At the Gaylord Texan – Experience ICE With a Weekend Getaway for Four
The Gaylord Texan in Grapevine, turns into something magical during the holidays. It's almost as if Santa and his elves make a special trip to Texas to decorate this awesome resort. Each year the Gaylord Texan features ICE! A story made entirely of ice and this year it is "The Nutcracker".


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Use our website's sophisticated search to encounter members who fulfill your criteria. Or just flip through listings and encounter singles that appear interesting.
Identified someone who takes your fancy? Send them a word or two or just a wink and see if they're interested. With a little luck you'll be on your way to discovering your perfect partner.
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New York City, New York 10019
United States
|Areas of Practice
|1) Intellectual Property
|Law School
|Fordham University School of Law
|Georgetown University (B.A., 1995)
|Most recent firm
|Davis & Gilbert LLP
|Relevant Jobs
Intellectual Property Attorney
Intellectual property law firm seeks federal litigator with at least 10 years of experience for its Orangeburg, New York office (Rockland County - close to Westchester & Northern New Jersey) to unde...
Apply now
Trademark Associate
Trademark Associate The candidate will work closely with clients to develop a strategic approach to managing, growing, and protecting their brands and ensure that successful brand management and glob...
Apply now
Intellectual Property Attorney
Intellectual Property Attorney The candidate must have outstanding academic credentials and excellent communication skills with 2 to 4 years of experience, including experience in drafting and prosec...
Apply now
|+ View more jobs
Coleen M. Meehan is a partner and trial lawyer in Morgan Lewis's Litigation Practice, resident in the Philadelphia office.
David W. Marston, Jr. is a partner in Morgan Lewis's Intellectual Property and Litigation practices and is a member of the firm's Class Action Working Group. He handles all aspects of litigation from inception through trial and post-trial appeals.


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GateHouse Media New England Appoints VP of Advertising
John Bordeleau has been appointed Vice President of Advertising for GateHouse Media New England.
Bordeleau is an experienced advertising sales and media executive who has led large sales teams in New England and beyond through successful multimedia transformations.
He most recently led Morphing Media, LLC, a consulting organization of his own founding, where he specialized in serving emerging companies in the business-to-business space and providing business solutions for clients in the areas of marketing, sales and employee development.
Previously, Bordeleau was divisional vice president for Comcast, where he led its New England and Houston divisions to multimedia success. Leading a staff of more than 425 across 21 sales offices, Bordeleau led his division to impressive revenue growth. Bordeleau also spent several years as corporate vice president of advertising sales for Century Communications in Connecticut, where he led the Fortune 500 company toward three-fold growth levels.
Bordeleau will serve as the senior sales leader responsible for all print and digital sales and advertising operations, including GateHouse Media New England's field advertising sales, digital sales, including Propel, major accounts and telecenter sales.
"I am very excited and honored to be given the opportunity to head up the sales operation of not only GateHouse Media New England but also Wicked Local Media Solutions," Bordeleau said. "I'm really impressed with the staff and the great people who work here, and the legacy of some of the GateHouse publications is incredible."
Sean Burke, president and group publisher of GateHouse Media New England, said Bordeleau's addition will be an asset to the company and clients.
"We're thrilled to have someone of John's experience and caliber join our organization and to lead our talented team of advertising professionals," Burke said. "John's skills and experience at building and leading successful sales organizations will help our sales team to better meet the needs of our advertising clients."


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Revel in the upsell tactics, uptempo snyths and local video production house stable of actors, especially Zelda Scott. She's prone to lines like "I'm down here in the hizzouse, you know, the heezy, with the GC posse, to get the 411 on GameCrazy," and "They can't hate on our used games."
"What games does he like to play?"
"Uh, his favorite is dragon games."
"Alright so based on what you're telling me, basically what we're gonna do is set you up with some accessories, a DVD remote, a wireless controller and we're gonna have to get you some memory cards to get you started."
Alright, so based on what I can see, you're totally clueless and I'm going to cram you for every add-on I can squeeze.
Caveat Emptor when entering the realm of Game Crazy. Be sure to have enough mana to cast your 9th level enchantment of "No Thanks, Just Looking."


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NIDA, MusiCares, GRAMMY Foundation Announce Teen Music Contest Winners
Three original music compositions that focus on personal experience living around drugs were the winners of the MusiCares and GRAMMY Foundation Teen Substance Abuse Awareness through Music Contest.
The first-place winners are Daevion Caves, an 18-year-old junior, and Jordan Atkins, a 16-year-old sophomore — both students at Alton High School in Alton, Ill. Second place goes to Markeist "Ghost" Jones, a 15-year-old sophomore from Plantation High School in Plantation, Fla. The third place distinction goes to Vera Marquardt, a 17-year-old in recovery at the Phoenix House Academy in Los Angeles. Also of note are the six runners-up in the contest: Jazmin Copeland, Sam Davis, Derek Hoggard, Jessica Johnson, Christian Pearson, and Lauren Vollaire.
The music contest was created to celebrate National Drug Facts Week, a seven-day observance launched this week by the National Institute on Drug Abuse. Sponsored by MusiCares and the GRAMMY Foundation, the contest was open to teens ages 14–18. Entrants were asked to compose or create an original song and/or music video that explores, encourages, and celebrates a healthy lifestyle or accurately depicts a story about drug abuse. Composers of all three winning entries will have the opportunity to attend a 53rd Annual GRAMMY Awards "Backstage Experience," a special backstage tour while artists rehearse for the live GRAMMY Awards show on Feb. 13, 2011, in Los Angeles. NIDA is part of the National Institutes of Health.
Listen to the winning entries.


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Results 6 to 10 of 16
Thread: Came up with some names...
April 23rd, 2012 02:46 PM #6
April 23rd, 2012 02:59 PM #8Senior Member
- Join Date
- Nov 2009
- Posts
- 1,527
April 23rd, 2012 03:13 PM #10
April 23rd, 2012 03:45 PM #12Senior Member
- Join Date
- Nov 2011
- Posts
- 1,401
Violet Willa Grace - I want to like this so much, but Willa Grace makes me think of Will & Grace...
Willa Adrielle - Lotta L going on and the connecting A sounds are a tad awkward to me, but I like both names (love Willa!)
Lilou Seraphine - Feels a little over the top frilly, but the rhythm is nice and it sounds beautiful
Harper Lyra Delphine - LOVE
Hadley Aurelia - also pretty!
Otsana Callilou. pr. Awts-on-ah Ka-lie-loo - There is so much going on in each name that I would probably pair each of these names with a more recognizable option.
Estée Luisa - Estée is really tied to the make-up company for me, but again the rhythm is great.
Sansa Mirabelle - I don't love the repetition of the two-syllable -a sound (Sansa Mira...), but each is alright on its own
Catelyn Rue pr. CAT-eh-Lin - I agree that this spelling will ALWAYS be mispronounced since it's a not-uncommon version of Kaitlin. Maybe Catalin or Catalyn would get you closer?
Damian Luca - Great!
Renly William - Not my fave. Renly looks a little odd. What about Ripley or Rafferty (nn Rafe)?
Henry Luca Wolf - great flow, and I like how Wolf gives gentle Henry a new spin! Love.
Kellan Jasper - Kellan isn't to my taste, but I think this works well
Scyther Ashton nn Sy - I still zero in on the word "scythe"--this name creeps me out... I'd prefer Syler Ashton, Silas Ashton, or Cyrus Ashton instead of Scyther.
Sibset-wise, you do seem to like both vintage names (Violet, Willa, Henry) and some modern (Hadley) and ethnic (Otsana) choices, which is awesome. I think these combos/reimagined combos and sibsets are cool:
Violet Avery/Harper Grace, Henry Luca Wolf, and/or Jasper Kellan Ash - vintage FN with bolder middles
Hadley Aurelia, Rowan Mirabelle, Teagan Lyra, and Kendrick Jasper - unisex FN with gorgeous, vintage MNs
Willa Delphine, Violet Aurelia, and Henry Jasper - all vintage
Harper Lyra Delphine, Damian Luca Wolf, and Kendrick Renly ___?
Violet Callilou and Aurelia Catalin
Otsana Delphine, Lirian Wolf, and/or Damian Luca - I think Otsana is so boldly beautiful that it needs strong siblings. Lirian is just exotic enough and Damian has a lot of punch on its own (though the two boys' names sound similar so I guess you wouldn't use them together)
Have fun! These choices are have tons of potential!
Last edited by ellenelle; April 23rd, 2012 at 04:17 PM.
April 23rd, 2012 04:25 PM #14


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I had such wonderful response to k.d. lang's version of "Crying" that I would be remiss not to include one more of hers which fits perfectly with Passion and Compassion month.
Several people mentioned her version of Leonard Cohen's "Hallelujah," a song I actually cited in my very first post.
k.d. lang's performance though … oh my god … her reverence for the song and Leonard Cohen at the end are awe-inspiring and had me in tears.
To tie this in with compassion, I'd like to refer you to two incredible pieces of writing. If you read nothing else today, please read these. They were recently written by my friend, author Les Floyd on the subject of compassion.
Aug. 9, 2011 London's Burning
Aug. 15, 2011 Justice and Compassion
This post is dedicated to author, Go Go Rach, as she both moves toward her life's passions and lets compassion into her life. ♥


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A direct measurement of the birefringence of a planar waveguide obtained by Na+ – K+ ion exchange was performed with a double Lloyd interferometer. The results are compared with those obtained by a round-robin test involving the same sample. Birefringence of as much as Δn = (2.0 ± 0.2) × 10−3 was measured.
© 1996 Optical Society of AmericaFull Article | PDF Article


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Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 321653, 19 pages
Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation
Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany
Received 1 June 2012; Accepted 25 July 2012
Academic Editor: Paula Ludovico
Copyright © 2012 Aswin Mangerich and Alexander Bürkle. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Aging is a multifactorial process that depends on diverse molecular and cellular mechanisms, such as genome maintenance and inflammation. The nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP1), which catalyzes the synthesis of the biopolymer poly(ADP-ribose), exhibits an essential role in both processes. On the one hand, PARP1 serves as a genomic caretaker as it participates in chromatin remodelling, DNA repair, telomere maintenance, resolution of replicative stress, and cell cycle control. On the other hand, PARP1 acts as a mediator of inflammation due to its function as a regulator of NF-κB and other transcription factors and its potential to induce cell death. Consequently, PARP1 represents an interesting player in several aging mechanisms and is discussed as a longevity assurance factor on the one hand and an aging-promoting factor on the other hand. Here, we review the molecular mechanisms underlying the various roles of PARP1 in longevity and aging with special emphasis on cellular studies and we briefly discuss the results in the context of in vivo studies in mice and humans.


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Pelvic floor muscle function in a general population of women with and without pelvic organ prolapse
Introduction and hypothesis: This study aims to examine the relationship between pelvic floor muscle function (PFMF) and pelvic organ prolapse (POP) in a general female population. Methods: Cross-sectional study on women aged 45-85 years. Validated questionnaires were used to assess pelvic floor muscle function. POP and PFMF were evaluated with vaginal examination. For statistical analysis chi-squared test for trend and analysis of variance were used. Results: Response rate to the questionnaire was 62.7% (1,869/2,979). No significant differences were found in muscle strength and endurance during voluntary muscle contraction between the POP stages. Women with POP stages I and II were significantly less able to achieve effective involuntary muscle contraction during coughing (38.3% and 37.7%) than women without POP (75.2%). Conclusion: Involuntary contraction of the PFM during coughing (that resulted in stabilization of the perineum) was significantly weaker in the women with POP stage I and II than in the women without POP.
|Additional Metadata
|Intra-abdominal pressure, Involuntary contraction, Pelvic floor muscle function, Pelvic floor musculature, Pelvic organ prolapse, adult, age distribution, aged, article, controlled study, coughing, cross-sectional study, disease severity, female, gynecological examination, human, major clinical study, muscle function, muscle spasm, muscle strength, pelvic organ prolapse, pelvis floor, population research, priority journal, questionnaire
|Persistent URL
|dx.doi.org/10.1007/s00192-009-1037-0, hdl.handle.net/1765/19460
|International Urogynecology Journal: and pelvic floor dysfunction
Slieker-ten Hove, M.C.P, Pool-Goudzwaard, A.L, Eijkemans, M.J.C, Steegers-Theunissen, R.P.M, Burger, C.W, & Vierhout, M.E. (2010). Pelvic floor muscle function in a general population of women with and without pelvic organ prolapse. International Urogynecology Journal: and pelvic floor dysfunction, 21(3), 311–319. doi:10.1007/s00192-009-1037-0
|Additional Files
|publisher's version Final Version
|pubmedcentral Accepted Manuscript


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ARCHIVED: Why is Outlook Express 5 for Mac OS downloading attachments to my computer without my permission?
Note: Outlook Express is not available for Mac OS X; use Entourage instead.
According to Microsoft, Outlook Express 5 has a security vulnerability, which may cause attachments in messages that are written in HTML to be downloaded and decoded on your computer. To solve this problem, update Outlook Express to the latest version. You can get the latest version from Microsoft's Mactopia site.
This is document aibj in the Knowledge Base.
Last modified on 2010-03-31 00:00:00.
- Fill out this form to submit your issue to the UITS Support Center.
- Please note that you must be affiliated with Indiana University to receive support.
- All fields are required.
- Fill out this form to submit your comment to the IU Knowledge Base.
- If you are affiliated with Indiana University and need help with a computing problem, please use the I need help with a computing problem section above, or contact your campus Support Center.


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Home Theatre Tickets Opera Anna Nicole
Anna Nicole Tickets
Find the Anna Nicole tickets you're looking for on NME ticket exchange, the world's largest ticket marketplace. Select an event to view the range of tickets available or view the calendar to see all the dates available with tickets. You can also sell your spare Anna Nicole tickets on NME ticket exchange, and listing tickets is free. All Anna Nicole tickets are covered by the NME ticket exchange Ticket guarantee!
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Bankruptcy Law
Bankruptcy Law Questions? Ask a Bankruptcy Lawyer.
I am filing a chapter seven bankruptcy in the state of missouri i live w my boyfriend..however our finances are completely seperate, i pay him $350 a month for bills etc and pay the cable and phone bill. Do i need to ibclude him on my chapter 7 bankruptcy...even tho our finances and checking accounts etc are completely seperate?
Response: No, you cannot include him in your bankruptcy case because you are not married.


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An ocean apart: Comparing transatlantic responses to the financial crisis
Has the EU-US relationship become a sideshow or is it still central to the global economy? Conflicting signals have been sent out since the outbreak of the global crisis. The creation of the G20 and its designation as 'the premier forum for international cooperation' suggest that attention and priorities have moved away from the traditional G7 focus on the transatlantic economy. But most of the key policy debates of the last two years have retained a characteristically transatlantic flavour. This applies to the controversy about the pace of consolidation which resulted in an open US-German rift at the Toronto summit in June 2010; to the discussion on the new bank capital ratios which again was essentially a euro- American affair; and to the broader conversation on the priorities of financial regulatory reform, for which the big action agendas have been the US Dodd-Frank Act and the European endorsement of a blueprint for coordinated supervision and a single European macroprudential body.True, other issues – the global rebalancing, or the creation of global financial safety nets – have had a distinctive G20 scope. But at least a fair share of the international debate has been transatlantic.There are reasons for this state of affairs. To start with, what is known as the global crisis has been first and foremost a transatlantic crisis. As discussed in several contributions in this volume, the wake of the crisis financial integration through portfolio diversification essentially remained an EU-US phenomenon.Accordingly the subsequent financial turmoil primarily affected the European and American financial systems, and other economies indirectly only, through trade or capital outflows. It is therefore natural to see the same two regions take the lead in setting the agenda for financial reform. Second, the problems they are facing in the aftermath of the shock – the travails of deleveraging, unemployment, the need for unconventional policy responses, the lowering of the growth potential, the rise of public debt, political pressures for protection – are largely common. Third, while they are not the main contributors to world growth, the EU and the US still constitute the bulk of the global economy, and what happens to them matters considerably for all.The US and the EU however are not responding to the same shock in the same way and this is what makes the comparison interesting. It is telling that the sovereign debt crises developed in Europe in the first half of 2010 and triggered a move towards consolidation while the US fiscal situation is by most standards worse than the aggregate European situation. It is telling also that the priorities of financial reform have not been the same. Clearly neither the policy space nor the policy traditions are identical and this portends significant divergence across the Atlantic. How far this divergence will go and whether policymakers on the two continents will disagree or agree to disagree is one of the key questions for the future of the global economy in the years to come.All this justifies a revival of the transatlantic economic conversation. The joint Banca d'Italia-Bruegel-Peterson Institute conference, held in Rome on 10-11 September 2009 with the support of the European Commission, aimed to contribute to the conversation through research and policy discussions. We hope that the papers collected in this volume will help foster a fact-based, analytically sound discussion.
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Left over shake and bake chicken recipe
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Time once again for SimDay, that event when the official Sims website gives fans of The Sims a load of information they probably already know. Yep, I'm being cynical again. Anyways, this week they've got two little links for us. While WorldSims may have published the chat transcripts yesterday, the official site has them today. Whoo-hoo. Here's another quote from the chat:
'What kind of pet stuff can you get?'To read the transcript (again) click here. The other link is for another preview of The Sims Unleashed from Gamespot. It's even fairly new! They added it to Gamespot yesterday, apparently. If you wish to read it then just click here. More SimDay next week!
'Most of the new objects in this pack are for pets so you will have plenty of shopping to do. Some of my favorite pet objects are the wooden cat climbing house and the fancy bed. There are baths, toys, scratching posts, litter boxes... everything you need to keep your pets happy.'
Written at 13:56 on Thursday, 19 September 2002 by Matthew.