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Erik Spoelstra – the head coach of the Miami Heat has finally won his first Championship. Being the youngest coach in NBA history, there were many who doubted Spoelstra when Pat Riley made him head coach at 37 years old in 2008. How could a man with no NBA experience, no titles lead a team? those were many questions asked by his doubters. Who would of thought Spoelstra would be ever in this position? Spoelstra once stated in an interview " If I did have a quiet moment to myself, I was thinking about coaching high school, not to be frank maybe thinking about coaching college." – Miami Heat News HD. I remember when he started working with the league as a video intern in 1995 in charge of watching NBA games for the Heat coaching staff.
This championship is as much his as any of the players. The Heat could not have won anything without the Big Three (or many others on the roster), but they could not have done it without Spoelstra either. At the post presser Spoelstra expressed " We have a brotherhood now, it makes this moment gratifying." And Spoelstra even mentioned Congressman Manny Pacquiao " Everyone knows I'm a Pacquiao fan." Congrats to the Heat and to our Fil-Am's very own Erik Speoelstra for making history!
*photo credit* NBA & ESPN
- Villanueva Boxing Gym is Home to the Ilonggo Youth - February 10, 2013
- An Emotional Mother's Cry For Justice: 24 year old Fili-Am Alvin Bulaoro Found Dead in Sleeping Bag in Albertson's Parking Lot in San Diego,Ca - January 5, 2013
- Jinkee Pacquiao and Erika Marquez pushing for their husbands' retirements - December 27, 2012
- Miss Universe fans world wide shocked : Miss Philippines " Janine Tugonon" places 1st runner up - December 19, 2012
- Viloria Wipes Out "Tyson" Marquez to become Unified Flyweight Champ - November 18, 2012
- 'Idol' Alum Jessica Sanchez Sings in San Diego - November 18, 2012
- Brian Viloria and Hernan "Tyson"Marquez make weight - November 17, 2012
- Viloria plans on testing Marquez with his Hawaiian Punch - November 8, 2012
- Exclusive Training Photos: Congressman Manny Pacquiao training hard for December 8 - November 7, 2012
- Erik Spoelstra makes history as the 1st Filipino-American in the NBA to win a Championship - June 21, 2012


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First lady Michelle Obama canceled two campaign appearances in Virginia on Friday because of the movie theater shooting in Colorado.
"In light of the tragedy in Colorado, the First Lady's events in Virginia today will be canceled," it said. "President Obama will address the tragedy in Aurora, Colorado in remarks in Ft. Myers, Florida this morning."
At least a dozen people were killed and dozens more wounded when a gunman opened fire at the midnight opening of the new Batman movie.

subset: commoncrawl


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SpeedZTR 48
Dixon mowers are no longer produced but we still service them and have Dixon parts available.
The Dixon SpeedZTR(Pronounced "speedster")48 has a heavy-duty Tri Force mower deck. This deck features a fabricated heavy duty steel pan combined with cast aluminum hubs, 1 inch shafts and an extra deep pan to furnish a great cut in all conditions.
This 3-blade Tri-Force deck is heavier duty than the stamped steel decks featured on the SpeedZTR 30, 46, and 54.Sporting twin hydrostatic transmissions and powered by a 24 HP twin-cylinder Kohler Courage engine, the SpeedZTR 48 can handle all your mowing chores.
Not only is this mower tough it is also comfortable with a THICK padded, Cordura™ (breathable fabric), spring-cushioned seat.
Quick Specs
· Rugged welded steel frame provides a sturdy foundation and is protected with a durable powder coat finish for longer life
· Battery leads to quick connect Dixon® Battery Manager.
· 6.5 mph forward speed mows faster so you finish quicker.
· Fusion blades(hardened edge) increase blade life 100-200% and stay sharp longer.
· 6-position cut height adjustment for 1.5 to 5" cut heights.
· Foot operated height adjustment.
· Padded swing-out steering levers precisely control speed, direction and braking.
· Twin hydrostatic EZT transmissions provides independent power to each rear drive wheel for zero turning radius maneuverability.
· Foam cushioned adjustable Cordura®
· Electric clutch PTO engagement.
· Rugged, yoke style front casters feature smooth tires-easy on the turf.
· 3 year parts and 2 year labor warranty for residential use. No commercial warranty.
· 18 X 9.50-8 Rear Drive Tires
· 11 X 4-5 front tires


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The Minnesota House failed to pass a bonding bill that focused on flood relief. Republicans couldn't garner enough support from their DFL colleagues to get the 81 votes needed to pass the bonding bill. It failed 76-57.
Several Democrats complained that the bonding bill didn't spend enough and didn't focus on the needs of the entire state. Rep. Lyndon Carlson, DFL-Crystal, said he's like to see the state borrow more because interest rates are low. He also said it would help the state's construction workers get jobs.
"When we talk about the infrastructure needs, there are a lot of projects that are shovel ready," Carlson said. "If we passed a bonding bill, you could literally, as soon as those bonds are issued, you could put people to work."
Rep. Larry Howes, R-Walker, is the chief author of the bill. He said Democrats are hoping that another bonding bill surfaces in a special session.
"The people who voted no decided either to roll the dice and try it another day and hope for more," Howes said. "I hope it works for them but I don't see it working for them."
Howes says another bonding bill could surface if lawmakers are forced into a special session because they failed to reach a budget agreement with Gov. Dayton. He says he's willing to work on a bonding bill but says it can't be as large as Dayton's proposal.
Dayton has proposed a $1 billion bonding bill in which half of the projects are picked by him and half of the projects are picked by the Legislature.


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The Grayson County Extension Office is hosting an agricultural information seminar that is designed to help farmers learn the tools to become a good advocate for the agriculture industry.
Farmers do a great job growing food and fiber, and it's time to start telling that story of how it's done. This valuable program will be held on Friday, March 25 from 9:30 a.m.-2:00 p.m. at the Extension Office.
The following topics will be discussed by featured guest speakers:
* Sending the Right Message – Jeff Nalley, Cromwell AG Radio Network.
* Using Social Media to Be an AGvocate – Carilynn Coombs, Kentucky Farm Bureau.
* Tips and Advice with Working with Radio & TV – Joanna Coles, Warren County ANR Agent.
* Using Your Voice for Agriculture – Warren Beeler, Kentucky Department of Agriculture.
This program is free and open to the public. You must call the Extension Office at (270) 259-3492 by March 23 to register. The Extension Office is located at 123 Commerce Dr. in Leitchfield. You should park in the back of the building and enter in the West entrance door.


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Are they DSP synths or sample playback or both. Excluding the two sampler ones... Could someone break it down for me. The specs I've seen don't really say...Also, are they any good? Anyone use them and use keyboard controlers with them?
Are they DSP synths or sample playback or both. Excluding the two sampler ones... Could someone break it down for me. The specs I've seen don't really say...Also, are they any good? Anyone use them and use keyboard controlers with them?
...and so on...
The Korg ELECTRIBE-A1 and EA-1 mkII are korgs tabletop analog modeling synth, with relatively simple and intuitive layout and design. They have 2 voices/channels and 2 VA VCO's per voice, with one doubling as a line in. Also the EA-1 models have Tempo delay, Distortion, and a chorus/flanger. Imho it's a very fun and good sounding VA synth and with the inclusion of an on board sequencers/pattern creator (that can record knob movments for shifting sounds) one can quickly fill up it's 1-4 bar 256 pattern bank.
*also note the New Korg ElectribeEMX-1
has built in Twin vacuum tubes and 9 drum parts, 5 synth parts, plus accent parts that let you add dynamic accents to the drum and synth parts (for a total of 16 parts). As well as having an arpeggiator: Ribbon + Slider Scale, Effects: 16 types x 3 (Chain), and Korgs new MMT (Multi Modeling Technology) engine (16 different oscillator algorithms )
Hope this helps
Last edited by 012; 07-06-2004 at 01:16 AM.
Marcus Bogue aka Marcus Boogie
www.MarcusBogue.com www.soundcloud.com/marcusbogue
When it comes down to it many "VA" and DSP synths use lookup tables to generate the base oscillators anyway. But to the electribes
ER - some tracks are DSP and some are samples
EA - all DSP (possible lookup on "oscillator")
EM - all samples
[b][url=http://home.netspeed.com.au/aistorm/]Sync² and Roland TR606 Mods[/url][/b]
[url=http://www.mp3.com.au/RythmEmulator/]Grab My tracks here[/url]
ER-1 DSP and PCM sounds.
Very accurate on tweaks, it's a shame the knobs are so tiny.
Electribes are GREAT machines for performing.
The delay effect is one of the greatest I've heard.
but my fav. feature, is the hability to register sounds on the 16 mini-pads during playing mode, so they will repeat on the next loop. That's so useful when playing on realtime...
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I travel a lot on business and really like Yelp, but when i do a "nearby" search it always seems to show me things in random order, not by distance. That's dumb. How do I get the results to be ordered by how far they are from my current location?
Well, it's not "dumb" that they organize the results that way, in my opinion at least, just a poorly chosen default. Or, perhaps, it's a good default and we are the odd guys out who prefer something different? In any case, I have talked with other people and heard the same complaint too. In fact, just recently I was in Las Vegas at a trade show and when I suggested to a colleague we use Yelp to find a good place nearby he complained of the same thing: the results aren't organized by distance.
Turns out that it's actually pretty easy to change that, but I haven't figured out how to change the default search to always sort by distance in Yelp. Perhaps that's something they could add down the road…
In any case, I'll show you how I reorganized the results on my iPhone.
To start, here's a Yelp "nearby" search:
If you look closely, you'll see that the places are 0.1 mi, then 0.09mi, then 0.7mi, then 0.9mi. Obviously not by distance or the Village Seafood Buffet would have been the #2 match, not #3. (the very first one, Nine Fine Irishmen, is a paid advertisement — hence the yellow background — so it's going to show up when I'm in the region regardless of how I sort the results).
Notice the buttons along the bottom too. This result is from tapping "Nearby", in case you haven't done that before.
Before we reorganize the results, however, tap on "Map" to see everything shown on a map. It's my favorite view:
Now let's fix this crazy organization!
To change it, tap on "Filter" on the top left.
Your temptation is probably to go straight for "Distance", but below it is the category you want to change: "Sort by".
The Sort By criterion defaults to "best match", whatever that is, but tapping on it reveals other options:
Ahhh…. so there are four options: Best Match, Distance, Rating and Most Reviewed. Each can be beneficial, allowing you to answer questions like "what's the best rated place near me?" and "which place has garnered the most reviews, good or bad?" but for what you seek, tap on the check circle adjacent to "Distance".
Now tap on "Search" on the top right again and you'll go back to map view, but this time the results are sorted by distance, not "best match":
Ahhh, that's better. To get to the list view, tap on… surprise! "List" on the top right.
Now go find a good place that's close and have a lovely meal.


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Immediate opening for small animal veterinarian. Experienced professional wanted to work full time, part time, or full time for two consecutive weeks every two months. Very flexible.
No after hour emergencies. Excellent salary (hourly on part time basis or negotiable full time salary). Accomodation available.
Small animal medicine and surgery.


text: An organization's data is critical to its business success, and become increasingly difficult to protect. Prolifics helps to implement integrated and optimized security controls with customized solutions designed to protect data from internal and external threats. Our security experts work closely with clients to establish a comprehensive data protection strategy that aligns with unique business requirements and provides insight into potential vulnerabilities.


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Carrie Underwood Blasts Through Colorado for Sold Out Blown Away Tour Shows – Exclusive Pictures
Carrie Underwood's husband may have gotten her roses for Valentine's Day, but there's no way that gesture — no matter how many chocolates were included — could surpass the sweetness of a packed room of screaming fans on the singer's Blown Away Tour.
The wildly successful run rolled through Colorado for two back-to-back sold out shows this week, including this one on Feb. 13 in Colorado Springs, where Taste of Country contributing photographer Joshua Lowe had a front row seat. Lowe reports that Underwood, along with tour partner Hunter Hayes, put on a passionate and energetic performance, which delighted the crowd. Obviously, the 'Two Black Cadillacs' singer made for a hot pre-Valentine's Day date for those in attendance. Couldn't be there? Don't fret — Lowe has made these photos available exclusively to Taste of Country readers for your enjoyment.
Of course, the fans at the show weren't the only ones who had a good time. After wrapping up her short Colorado run, Underwood tweeted, "Thanks, Colorado, for the wonderful energy over the last two shows! I can always tell when I'm in a great place full of great people…"
Carrie Underwood Blown Away Tour Pictures — Colorado Springs, Co., 2/13/13


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Author has written 4 stories for Yu Yu Hakusho.Sekai: Dude!!! well i haven't put up many fics yet but.. hey i'm working on them!!!!!! DO NOT FEAR!! ok now that i have regained my composure...
hiei: composure..what composure?
sekai: -_- * tugs in her sress punching bag (aka: kuwabara) and starts beating the s*t out of it*
kuwabara: OO;
hiei: hn. *looks amused at his klumsy coworkers horrible fate*
sekai: *while beating up kuwabara* i am totally obsessed with anime as you can partly see. my favorite shows include Yu Yu Hakusho, *kicks kuwabara's head with a round house kick* Rurouni Kenshin, Inu-yasha, Gundam Wing, G Gundam, Yu-Gi-Oh*punches kuwabara in the nose* and many more that are loged in my brain some where and lost forever.* knees kuwabara's grion*
sekai: my character that i have made is my self and is consiquently named after me. She is a fire deamon with a green jagan eye instead of a purple one like hiei's got!(more info on hiei go here: )
hiei: you talk like sekai is a different person, sekai...'
sekai: heh..heh..i frequently do round robins with my freinds who are also ff.net authors. ummm... i'll have to get back to you on their pen names...Wait NO! i remember now! ^^
hiei: and her memory surges...
sekai: There's:
sekai: i will try to update as much as i can.
hiei: If you want to talk to her then her aim screen name is hiei1005...ummm...ya...sofar i've been the 2nd person to pronounce that right
sekai: but it shouldn't be too hard fo these anime/nonanime lovers...ne? ^^


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Antonino Giovanni Ribisi is an American actor who was born in Los Angeles, California. His parents both have careers in the entertainment industry. His mother, Gay Ribisi (née Landrum), is a talent manager for actors and writers, and his father, Albert Anthony Ribisi, is a musician. He has a twin sister, actress Marissa Ribisi, and another sister, Gina. Giovanni is of Italian (from his paternal grandfather), English, and German descent.
His mother helped to launch his acting career, which began with an appearance on two episodes of the TV show "Highway to Heaven". This followed with numerous roles on television. In 1996, he gained the role of Phoebe's half-brother on the high profile "Friends", which boosted his career.
He became involved in films, which included roles in Tom Hanks' "That Thing You Do!" and Steven Spielberg's "Saving Private Ryan". In 2012, he is appearing in "Contraband", _Ted (2012_) and "Gangster Squad".
Name: Giovanni Ribisi
Known for: Avatar
BirthDay: 17, Dec ,1974


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Vikings lose to second seed in Section 7AAA play
Head coach Jerome Huselid said nerves were a factor in the postseason matchup and that the Thunderhawks took North Branch by surprise with a change in defense.
"I think we were expecting more man-to-man, and they came out with a two-three zone and a press," Huselid said. "We handled the press really well, but they slowed us down and our shots just didn't fall."
The Vikings came out firing in the second half, though, outscoring Grand Rapids 38-29 in round two. The Vikings came within one point with less than a minute to go, but were unable to surpass the physical Thunderhawk squad, losing 61-56, an improvement from North Branch's double-digit loss earlier this season.
Huselid was pleased with the last-ditch effort by his girls and their attempt to up the tempo of the game in their favor.
"I think we came out and played with more urgency," he said. "We had come out flat in the first half, didn't move as well as we could have in the practice before and weren't as energetic as usual, so that worried me. But we had a couple of good plays, got our energy up, shots started falling, so that was good to see."
Sophomore Morgen Coleman led the Vikings with 18 points, 12 rebounds and four steals, followed by sophomore Courtney Selbitschka with 14 points, eight rebounds and three steals. Senior Haley Huset got in foul trouble early, but still contributed 10 points and five rebounds before fouling out in the final minute. Senior Mikayla Carlson added six points and two steals.
North Branch will graduate four seniors: captains Huset and Carlson, and Kora Amunrud and Kadie Mattson.
Huselid had good things to say about all four.
"All of them were very good in their roles," Huselid said. "Haley was our 1,000-point scorer and took a lot of responsibility — we will miss her a ton. Mikayla was a starter and is just a phenomenal kid in so many ways. She is a true team player. Kora improved so much these last few games and would come in off the bench and get us some big rebounds. And Kadie is a great athlete. She didn't get a lot of time on the court offensively but did good things defensively and is very unselfish."
North Branch went 13-15 this season in what was their first year in the Mississippi 8 Conference. The Vikings went 4-10 in Section 7AAA and 2-5 against conference opponents.
"We had a great season and had a lot of fun," Huselid said. "The girls gave great effort all year. Our new conference is several steps up in competition and in quality teams and players. It took awhile to get things going and we did some things different that took some time, but I thought we played very well down the stretch."


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Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV Subjects
This study has been terminated.
(Incomplete data)
Information provided by:
ClinicalTrials.gov Identifier:
First received: September 1, 2005
Last updated: November 9, 2007
Last verified: November 2007
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been terminated.
|Study Completion Date:
|No date given
|Primary Completion Date:
|No date given


text:
NESEA's annual Green Buildings Open House (GBOH) is the biggest sustainable energy event in the northeastern United States. GBOH is an opportunity for the public to learn about energy improvements in their communities, and connect with NESEA members who are often behind the designs, upgrades, and products seen on the tour. In 2012, nearly 10,000 people toured 500 homes, businesses, and public buildings. 95% reported meet their goals – whether learning about sustainable building, meeting practitioners, or getting inspired! Please visit www.nesea.org/gboh for more information.
-Instructor name not provided-
-Course instructor credentials not provided-
-Training provider credentials not provided-
-Course hours accreditation not provided-
A Home Power staff member will review all newly-submitted events before they're made public.


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Ask Health Experts and Get Answers to Your Health Question ASAP
Is it any more dangerous to take the Advil with the Vicodin? Is that combo especially dangerous?
Thanks so much, I am worried and want her to get more treatment. I will pass on the info, although I knw she wont want to give up the meds for now. I will press her to return to the doctor.


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Roots in photography
Roots in photography
Sculpture. Made of 2 by 2 inch puzzle pieces. Photo paper on chip board.
"No tree can grow tall and reach high without nurturing its roots."
What started out as just another subject in the College of Fine Arts and Design major in Advertising turned to a passion for creativity.
I had entered the college originally to learn how to be a comic book illustrator. Unfortunately I was not good handling the pencil. Dedication and practice only took me so far. Then I was exposed to this medium of photography. Immediately I got hooked with fiddling around buttons and dials, trying different combinations, listening and learning from professionals, travelling to beautiful places, and interacting with people.
And when I began to have mastery over the basic of photography. I looked over its least explored dimensions. Looking beyond documenting reality to exploring creation. Merging the craft with others to create something different, not too instantaneous yet spontaneous and very personal.
Still from time to time I go back to my mentors. To ask guidance. To acknowledge their contribution. And to nurture the roots where I came from.
Thank You!


text:
How to revolutionize cancer immunotherapy trials
A look at various factors that can influence cancer immunotherapy trials through the lens of an immunologistAugust 10, 2017
A look at Nektar Therapeutics immunotherapy pipeline
Update on Nektar Therapeutics IO portfolio and a look at their burgeoning autoimmune disorder pipelineJuly 24, 2017
Can we use immunotherapy to treat or delay Alzheimers Disease?
How we could use our immune system against Alzheimer's?July 20, 2017
Can AstraZeneca leapfrog the competition in lung cancer AGAIN?
Durvalumab grabs pole position in unresectable NSCLC amongst IO compoundsMay 12, 2017
On Gritstone and neoantigens
A look at a promising biotech in the neoantigen space - what's their approach and how might it fare?May 4, 2017
AACR 2017 Preview 3
After exploring a mechanistic approach and a tumour type as part of our AACR annual meeting coverage, in…March 8, 2017
Novel Way to Improve Checkpoint Inhibitor Efficacy
A look at another surprising factor that might affect efficacy of cancer immunotherapy and checkpoint blockade.March 1, 2017
A completely novel approach to targeting hematologic malignancies
A look at the deeper side of research - how the spliceosome and RNA splicing may be useful in cancer research.February 15, 2017
Novel Targets in Multiple Myeloma
Going beyond proteasome inhibitors and IMiDs in multiple myeloma - what novel targets are attractive?February 8, 2017
A manifesto for immuno-oncology research
A draft manifesto for IO in cancer research and what we need to learnFebruary 1, 2017
Understanding the Mutational Landscape of Metastatic Breast Cancer
How crowdsourcing data from breast cancer patients may help future clinical R&DJanuary 24, 2017
Does Neon Therapeutics lead the Neoantigen field?
Update on Neon Tx as they move into commercial new product development with their neoantigen platform.January 13, 2017
The future of our cancer research business
A look at the emerging trends we can expect in 2017 for cancer researchJanuary 3, 2017
How the Leukemia Lymphoma Society plans to Beat AML
Tackling heterogeneity in older people with AML using novel targeted therapies.December 21, 2016
7 Things I Learned at #ASH16
Highlights (Part 1) from 2016 ASH Annual Meeting in San Diego - 7 initial impressionsDecember 6, 2016
Making breast cancer cells become normal again
Can we revert the mutant phenotype in breast cancer and return to a normal, non cancerous phenotype?November 30, 2016
ASH16 Abstracts are out! So What's Hot at ASH16? My Initial Impressions
Initial impressions of abstracts for ASH16 in San DiegoNovember 3, 2016
Glycomics The Third Language of Life
How will glycomics impact cancer research? Some interesting new developments are emerging in this fieldOctober 27, 2016
How do you calculate Immunoscore? A tour of HalioDx
Audio Slideshow tour of HalioDx lab that shows how digital pathology is used to calculate Immunoscore an immune based colon cancer assayOctober 3, 2016
François Romagné Accelerates Cancer Immunotherapy Innovation in Marseille
Interview with Professor François Romagné, Scientific Director of MI-mAbs, an immuno-oncology drug discovery venture in the Marseille Immunopôle cluster.September 21, 2016
HalioDX CEO Vincent Fert outlines commercial strategy for Immunoscore in US and Europe
Interview with HalioDx CEO Vincent Fert on commercial strategy for Immunoscore diagnostic test.September 14, 2016
Modelling the Tumour Microenvironment
Interview with Prof Fran Balkwill from Barts Cancer Institute on 3D modelling of the tumor microenvironment in ovarian cancerAugust 22, 2016
PsiOxus is a cancer immunotherapy company to watch – Part 2 of an interview with CEO John Beadle
Part 2 of interview with PsiOxus Therapeutics CEO Dr John Beadle discusses corporate strategy and challenges faced by an emerging biotech company.August 17, 2016
Can PsiOxus become a world leading immuno-oncolytic virus company?
An innovative and promising approach to cancer immunotherapy using adenoviruses to deliver multiple warheads to tumoursAugust 16, 2016
Biotech Mailbag – Jounce & the CAR T Race to Market
July Reader Q&A - thoughts on Jounce, Celgene, BMS, J&J and CAR T cell therapies...July 27, 2016
Reader Mailbag – TCR T cell Gene Editing in Multiple Myeloma
Gene editing is coming to the US CAR T cell space - what's happening and what will the impact be?June 17, 2016
5 Important and Emerging Trends from ASCO 2016
A number of points of strategic importance fell out of the ASCO data dump. What are they and why do they matter?June 9, 2016
Drug Discovery Targets Cancer Vulnerabilities
Commentary from the AACR Precision Medicine Conference in Miami on Targeting the Vulnerabilities of Cancer.May 20, 2016
Breaking the Immunology Rules – an interview with Dr Michel Sadelain on how CAR T cell therapy will crack solid tumors
At the recent AACR meeting, Dr Michel Sadelain gave a presentation on turbocharged CAR T cells, and shared some of his ideas on how to move the field forward.May 5, 2016
Can ADCs be adapted to tackling MRSA?
Can we use technological approaches from oncology to applying creative ways to treating bacterial infections?April 27, 2016
Targeting Acquired Resistance in Prostate Cancer
The discovery of a novel target in castration-resistant prostate cancer offers the potential to overcome or delay acquired resistance to enzalutamide.April 4, 2016
Understanding the Cellectis UCART19 Case Report – Part 2 of an Interview with Prof Waseem Qasim
Part 2 of ASH 2015 interview with Prof Waseem Qasim (GOSH) on the first in man gene edited allogeneic CAR T cell therapy.December 16, 2015
Potential of Gene Editing – Part 1 of Interview with Prof Waseem Qasim
Part 1 of an interview with Prof Waseem Qasim.December 15, 2015
Is ocrelizumab a game changer in MS?
At the 2015 European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting Barcelona on Friday, Dr Stephen Hauser (UCSF) presented the data for octrelizumab, an anti-CD20 monoclonal antibody, on behalf of the investigators in the OPERA trial.October 11, 2015
Novel Targets Podcast 6 – Immune Agonists
What happens when we literally step on the gas with immune agonists?September 24, 2015
Where are the breakthroughs coming in Soft Tissue Sarcoma?
Interview at ECC 2015 with Dr George Demetri on new developments in Soft Tissue SarcomaOctober 6, 2015
Biotech Strategy questions answered on neratinib, bavituximab, enzalutamide and more!
Insights on targeted therapies from ASCO - questions from subs on neratinib, bavituximab, enzalutamide, Gilead's pipeline and MDSCs...June 17, 2015
Yumanity hopes to impact humanity – an interview with Dr Susan Lindquist
Yumanity seeks to transform drug discovery for neurodegenerative diseases caused by protein misfolding.January 21, 2015
How Syros are changing biotech R&D
Transcription factors are becoming a new buzzword in cancer research - why are they important for drug development?January 15, 2015
bluebird bio CEO Nick Leschly seeks to make hope a reality
Bluebird bio is an emerging biotech company with a novel lentiglobin gene therapy in development that could revolutionize the treatment of beta-thalassemia and sickle cell disease.January 14, 2015
Will Bluebird Bio transform beta Thalassemia and Sickle Cell Anemia?
There is no available cure for patients with beta-thalassemia or sickle cell disease, but new developments are very encouragingJanuary 12, 2015
Biotech Strategy Blog – the year of the paywall
Thank you to all our subscribers for a great year!September 17, 2014
Can Cellectis Revolutionize CAR-T cell immunotherapy?
Cellectis is a Paris based biotechnology company with a "blue ocean" strategy that, if successful, could revolutionize cancer immunotherapy.July 7, 2014
Healthcare Innovation in Action: Designing for Dementia
Can design make a difference to those with dementia? Liverpool City Council's award-winning Sedgemoor Dementia Support Centre shows how design innovation can stimulate memories and offer improved quality of life.April 28, 2014
Everton FC leads the way in community dementia support
Everton FC and Mersey Care NHS Trust use football memorabilia and activities at Goodison Park to stimulate memories and support members of the local community with dementia.April 23, 2014
Update on anti-PD-L1 cancer immunotherapy
Roche Genentech are developing their anti-PD-L1 as both monotherapy and also in combination with targeted therapies in lung, melanoma, renal and colon cancers. How is the early development progressing?January 22, 2014
ASH 2013 Stunning ALL data with Novartis CTL019 CAR Therapy
UPenn and CHOP are using genetically modified chimeric antigen receptor (CAR) T cells to treat patients with B cell cancers such as ALL, B cell NHL, CLL and other B cell malignancies. At ASH, the impressive data from adult and pediatric ALL was presented. This post includes insights on this approach and an interview with Dr Stephan Grupp on the pediatric data.January 9, 2014
2012 was a Grand Cru year for the FDA with 39 NMEs approved
FDA approved 39 new molecular entities in 2012. This is the highest number in the last 10 years. However, approval rate is not a surrogate benchmark for the state of innovation given that it can take several years to bring a new drug or biologic to market.January 2, 2013
Innovation in Action: helping people to see again
FDA approves first artificial retina prosthesis, the Argus II from Second Sight. This is not a bionic eye. To date, only crude images can be detected. There is no dramatic restoration of sight or vision, instead retinal prostheses currently only offer the ability to detect light and large shapes. Several companies and research groups including Bionic Vision Australia are working on innovative retinal prostheses that aim to restore some vision.September 17, 2012
Creating an artificial jellyfish to model the human heart
Creation of an artificial jellyfish advances the potential to reverse engineer the human heartAugust 20, 2012
The Potential of Gene Therapy to Restore Hearing Loss
Restoration of hearing in mice by gene transfer is a major breakthroughAugust 14, 2012
Repetitive brain injury from high impact sports generates similar pathophysiology to traumatic brain injury in soldiers blown up by IEDs
Several retired American Football stars have ended up with chronic traumatic encephalophy (CTE). It's similar to Alzheimer's disease in that the brain ends up with neurofibrillary tangles. CTE has also been seen in soldiers who have experienced blast induced traumatic brain injury (bTBI) from improvised explosive devices (IEDs)May 21, 2012
TEDMED 2012: Francis Collins on how to brings drugs to market faster
It can take 14 years of research and the screening of 10,000 compounds to bring 1 new drug to market.May 18, 2012
Innovation in Neurotechnology: how a paralyzed person uses thoughts to control a robotic arm
A tetraplegic (all four limbs paralyzed) is able to use her mind to control a robotic arm, 15 years after she became completely paralyzed & unable to speak.May 16, 2012
A personal perspective on Alzheimer's: my mother doesn't dance anymore
I have a personal interest in Alzheimer's disease. It's an area where innovation needs to catch up with demand for treatment and therapies, not to treat it when it's happened – it's too late to untangle the damage, but to delay it's occurrence in those at risk.March 9, 2012
Implanted Wireless Microchip offers Osteoporosis Drug Delivery that improves patient Quality of Life
Robert Farra of MicroCHIPS, Inc. and research collaborators, describe a first-in-human testing of a wirelessly controlled drug delivery microchip.February 20, 2012
Today is Innovation Day at Childrens Hospital Boston #iDay
Children's Hospital Boston has an Innovation Acceleration Program focused on supporting "clinical care that impacts patients around the world."February 14, 2012
Blocking Sema4D may be a new osteoporosis target
Research published in the November 2011 issue of the journal Nature Medicine has highlighted a new potential target for osteoporosis drug development that acts on osteoblasts and promotes bone formation.November 10, 2011
Discovering the cause of Lou Gehrig's disease
Scientists from Northwestern University in Chicago report findings that could help develop drugs for patients with Amyotrophic Lateral Sclerosis (ALS), more commonly known as Lou Gehrig's disease.August 31, 2011
Can we halt memory loss as we get older?
New research offers the hope that in the future we may be able to reverse or slow-down the age-related memory loss and cognitive defects we would otherwise experience.August 26, 2011
Innovation – should companies take bigger risks and outsource pharma R&D?
"Rather than do research in house, companies should close their labs and outsource the work to tiny, nimble startups that can explore bigger, crazier ideas."August 3, 2011
How we may be able to rebuild The Six Million Dollar Man
The Six Million Dollar Man was fiction, but it is becoming closer to reality as a result of new research into how artificial limbs can integrate with human tissuesJuly 11, 2011
How does sunburn cause pain?
Research by John Dawes and colleagues at King's College London & University College London has shed new light on how sunburn causes pain.July 8, 2011
Regenerative Medicine: Tissue Engineered Airway Transplant
Researchers from University College London led by Prof. Alexander Seifalian designed and built a polymer based nanocomposite tracheal scaffold, which was then seeded with the patient's own stem cells.July 7, 2011
Science Translational Medicine on Innovation – part 1
With an image of Rodin's bronze "The Thinker" on its cover suggesting deep thought and insight, the journal "Science Translational Medicine" analyzes the state of innovation.July 7, 2011
Will the future offer artificial retina transplants?
A Nature article shows, for the first time, the ability to generate a three-dimensional culture of neural retinal tissue from mouse embryonic stem (ES) cells.April 29, 2011
The future of Parkinson's disease, part 2 of an interview with Dr Todd Sherer, Chief Program Officer, Michael J Fox Foundation
"The understanding of the genetics of Parkinson's will certainly form the building blocks of some future breakthroughs. Now that we have very tangible therapeutic targets that we know can cause Parkinson's, it makes a much more rational directed drug development program."April 8, 2011
Making a difference to Parkinson's Disease Research, an interview with Dr Todd Sherer, Michael J Fox Foundation
"The goal of the foundation, the goal of all the research that we are supporting is to develop new therapies for Parkinson's disease patients."March 31, 2011
Of Mice and Men
The March 17, 2011 edition of Nature, highlights how innovative preclinical animal models are having an impact on drug development.March 25, 2011
Technology Innovation – the challenges and opportunities with robotic surgery
At the European Association of Urology (EAU) annual congress in Vienna, Associate Professsor Axel Merseburger from Hannover in Germany discussed some of the challenges with robotic surgery for prostatectomy or partial nepthrectomy.March 19, 2011
Argus III is the next generation of artificial retina from Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory (LLNL) have produced an excellent video about their manufacturing of the Argus™ III artificial retina.March 14, 2011
Artificial Retina Project shows power of collaboration to bring new products to market
The Artificial Retina Project is a case study on the success of collaboration.March 14, 2011
New artificial retina restores some visual perception and improves autonomy
Detecting a door or a window may not be a big deal for all of us with normal vision, but for those who lose their sight, e.g. through retinitis pigmentosa (RP), a new "artificial retina" now provides hope of a better quality of life.March 8, 2011
Targeting Sclerostin in Osteoporosis
Sclerostin is a protein produced by osteocytes within bone that inhibits bone formation. It is thought to pass through the surface of bone where it acts on osteoblasts (cells responsible for bone formation). There it binds to low-density lipoprotein receptors and inhibits the Wnt/beta-catenin signaling involved in bone mass regulation. Promising phase 2 trial data for a novel sclerostin inhibitor, romosozumab (AMG 785), in osteoporosis has just been published in the New England Journal of Medicine.March 10, 2011
Merck's cathepsin-K inhibitor odanacatib in osteoporosis
Cathepsin-K inhibition is a novel approach to osteoporosis treatment and Merck's odanacatib is leading the way in this new class of drugs.February 11, 2011
Emerging drugs in development for Osteoporosis
The market opportunity for osteoporosis remains significant, affecting 44 million people in the United States over the age of 50, resulting in healthcare costs in excess of $15 billion a year.February 8, 2011
New research points to role of Cystic Fibrosis Transmembrane Conductance Regulator Signaling in Emphysema
Developing drugs that target cystic fibrosis transmembrane regulator (CFTR) protein and mediate ceramide may have an important role to play in the treatment of emphysemaJanuary 10, 2011


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Gender: M Meaning of Maguire: "son of the beige one" Origin of Maguire: Irish
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An operating room registered nurse with 10 years of experience, Cam Westhead knows how critically important public health care is to working and middle class families. He is dedicated to protecting and improving our public health care, education, and seniors programs.
Westhead has a Bachelor of Arts degree from Nipissing University and a Bachelor of Science in Nursing from the University of Toronto. He settled in Bragg Creek in 2011 after living in Calgary and Canmore from 2005 and enjoys the recreational opportunities the Banff-Cochrane constituency has to offer.
As an elected workplace representative for more than four years for nurses at the Foothills Hospital and across the province, Westhead determinedly advocated for improved patient safety and optimal conditions for working people.
He is committed to strengthening the province's health care system, protecting the natural environment, and a strong economy.


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The final exam: National survey tests business acumen of veterinary students; more study needed
The findings underscore the need for better business education for veterinary students, reports Dani McVety (Class of 2009) from the University of Florida's College of Veterinary Medicine.
Here are some of the survey's questions, answers and results:
1. (True or false) A veterinary practice's gross income is the amount of money made after subtracting various expenses.
2. Which of the following is not an accurate statement about a balance sheet?
3. (True or false) As a licensed veterinarian, you are invited to fly across the country to interview for a position as a new associate. You purchase a plane ticket and pay for a hotel room and a few meals. These expenses are deductible on your tax return.
4. (True or false) Instead of cash, a client pays her bill with rare, valuable stamps from her prized stamp collection. The market value of the stamps is included in income.


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Gerald Jacksits
Baltimore, MD
1 Stars
Not Recommended
February 3, 2012
Not good quality, poor finish throughout, some of the finish was scrached off, handles had dents, threaded handles get loose on rod and you have to keep tightening them. Brush bristles fall out.
Pros:Save space on the fireplace brick landing
Georgetown, Texas
5 Stars
I would recommend this item to a friend.
Woodfielel Oil-rubbed Bronze 4 Piece Fireplace Tool with Round Base
November 3, 2011
I got this for a friend as a house warming and she is so pleased with it. she says the color is perfect and she would have got the same thing. The color of it is so perfect with all her brown tones in the living room.
Pros:Everything. It looks better that the picture on the web-site. It goes together with ease.


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Author | Priyanka Mehra | Monday, Oct 19,2015 8:17 AM
According to TAM data, Week 41 saw a rise in the viewership of Hindi GEC genre by 8 GRPs.
In case of Zee TV, Grand Finale of Amul Dance India Dance 5 and featuring of Movies like Hum Saath Saath hai and Welcome have worked well for it. Qubool Hai, Sarojini and Tumhi Ho Bandhu SakhaTumhi in the early prime slot have helped Zee grow by 12 GRPs.
Sony's Airing of Hindi feature film ABCD 2 on Saturday contributed 80% of the 12 GRP growth which channel saw this week. Also its Mythological shows 'Sankat Mochan Mahabali Hanumaan', 'Bharat Ka Veer Putra-Maharana Pratap' and 'Surya Putra Karna'gave better returns this week than the week before.
Colors is the highest gainer with 14 GRPs in Week 41.
Recently, Colors has tweaked its program timings in the Prime time. With the increase in the Duration of Ishqka Rang Safed, the succeeding show timings have changed. Its prime time which was from 18:30-22:30 has now changed to 18:30-23:00.
Jhalak Dikhhla Jaa, Chakravartin Ashoka Samrat and Ishq Ka Rang Safed were responsible for 70% of the Channel growth in this week.
Compared to Zee and Sony which mainly grew on its weekend properties which were mostly movies and Grand Finale of Reality show; Colors has grown on its weekday properties.
The Rating of Bigg Boss which is set to release next week is more likely to strengthen Colors' position further.


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- Articles
- Videos
- Photos
- #WeAreUK
- About Cal
- Camps
A "players-first" coach with a penchant for helping people reach their dreams, John Calipari has guided five teams to the Final Four, led one to a national championship and helped 29 players make it to the NBA during his 22-year college coaching career. Coach Cal, who just completed his fifth season at the helm of the Kentucky basketball program, reached the mountaintop in his third year in Lexington, guiding Kentucky to its eighth national championship and his first national title. In becoming only the second coach in NCAA history to lead three different schools to the Final Four, he has racked up nearly 600 victories, 15 NCAA Tournament appearances, five Final Fours and numerous national coach of the year honors. Calipari has sent 31 players to the NBA, including a record five first-round picks in the 2010 NBA Draft and a record six picks in the 2012 NBA Draft. He's coached three No. 1 overall picks, more than any other coach. His foundation, The Calipari Foundation, has raised millions of dollars millions of dollars to help the lives of those in need in the Commonwealth and across the country. Calipari is author of the New York Times Best Seller "Players First: Coaching from the Inside Out."
Metz Camfield is the editor of CoachCal.com and oversees Coach Calipari's social media platforms. Before CoachCal.com, Camfield was an assistant media relations director at Ole Miss, serving as the primary sports information director for the volleyball and softball programs for two seasons before moving on to becoming an assistant contact with football and the primary contact for baseball. He was also the website coordinator for OleMissSports.com. Prior to his time at Ole Miss, Camfield, a Kentucky graduate, worked in the media relations department at UK for two years. During his time at UK he worked with the men's and women's basketball programs, as well as cross country, track and field, men's and women's golf, swimming and diving and women's tennis. Camfield also wrote for the Kentucky Kernel, UK's daily, student-run newspaper, where he was an assistant sports editor and the men's basketball beat writer.
Eric Lindsey is the editor of CoachCal.com and oversees Coach Calipari's social media platforms. Before CoachCal.com, Lindsey was a writer at UKAthletics.com. Lindsey served as the primary developer in the University of Kentucky's push to integrate new and social media into the athletics department. He conceptualized, directed and wrote for "Cat Scratches," UK Athletics' official blog, covering men's and women's basketball and football in their entirety, as well as in-depth and unprecedented access into all of Kentucky's 22 sports through features, game stories and more. Lindsey has written for the Lexington Herald-Leader, freelanced for several publications, including the San Diego Union Tribune, and was a former managing and sports editor at the Kentucky Kernel, UK's daily, student-run newspaper.
Chad Hobson is co-owner of Rocker, the Lexington, Kentucky-based technology consultancy responsible for managing and producing the creative, video, and technical aspects of CoachCal.com. If you see Coach Cal out and about in public and this face is nearby with a camera, be sure to say "hi!"... you may end up in the next video feature.
Chris Reynolds is a freelance photographer for CoachCal.com. Born and raised in Lexington, Ky., Reynolds attended the University of Kentucky where he worked as a photographer for the Kentucky Kernel. Since then Reynolds has been published in several music and sports publications.
Ken Howlett is the editor of the popular UK blog "A Sea of Blue" (aseaofblue.com) and co-hosts "Wildcat Wednesday," a weekly University of Kentucky radio program on 1340 WBGN in Bowling Green, Ky. He is also a contributing writer to "Wildcat Tip-Off," a UK basketball yearbook published by Maple Street Press.
Guy Ramsey serves as director of strategic communications at the University of Kentucky, where he oversees the social media efforts of UK Athletics. He manages and writes for "Cat Scratches," the official blog of UK Athletics, covering all 22 of the Kentucky's varsity sports.
Tim Asher is in his 14th year as the Wildcats' basketball video coordinator after serving the previous 12 seasons as the team's traveling videographer. In his role, Asher oversees all of the basketball program's video needs, including maintaining the Wildcats' sophisticated editing system. He has also been the lead on "This is Kentucky Basketball" coach's show, shooting all behind-the-scenes aspects as well as the majority of the Q&A's, Inside the Play segments and more.


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I do need help with itinerary suggestions and recommendations, but sometimes it's good to have something on paper to get started. Below is a itinerary I came up with. Would this work? What should I change? What are problems with this itinerary that I've not realized? What would be a better suggestion? Should I do in reverse order? Thanks!
Arrive late and overnight in Kalispell
Take Rt. 2 to East Glacier
Visit Two Medicine
Drive to Many Lodge,overnight there.
Expore area around Many Lodge
Overnight Many Lodge
Drive to Waterton Canada
Explore area
Return drive to Many Lodge and overnight there
Drive to West side via GTTS Road
Overnight at either Lake McDonald Lodge
or in Apgar?
Drive to Kalispell, 2 pm flight home
What needs adjusted on this itinerary? Thanks!
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Glacier National Park Itinerary: Request Help
I do need help with itinerary suggestions and recommendations, but sometimes it's good to have something on paper to get started. Below is a itinerary I came up with. Would this work? What should I change? What are problems with this itinerary that I've not realized? What would be a better suggestion? Should I do in reverse order? Thanks!
Report Abuse
I think I forgot to add, for us, this is mosly a road trip, sighsee by car. Some scenic walks are fine, but no long hikes. Thanks.
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I think it's a good schedule.
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Don't try this before May or you will find the GTTS road closed by snow. Do you have passports to come back from Canada?
The gate where they block off the west end of GTTS Road is near the parking lot for Lake McDonald Lodge.
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The GTTS road didn't open until nearly mid-July this year(I think thats about right anyway). I think even June 1 would be very iffy.
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It opened June 24th last year - several days after the estimated opening.
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When on the east side you might want to visit the museum of the Plain Indian in Browning.
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Nope, THE GTTS road had it's latest opening ever this year(except during the war). July 13, 2011. Google it and you will get many sights that tell you this. I was supposed to have been there, but due to flights not being able to get to the airport I canceled(partly in due to part that I knew the road was closed, so I wouldn't even be able to get to Logan Pass).
Here is a link to the Parks Website announcing the opening day for July 13, 2011.
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I looked back and yes in 2010(last year) it did open on June 24.
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spiro, I didn't know if the "nope" was for me or not.
I was there. I happened to be in one of the first vehicles to get to Logan Pass. The bathrooms were open but they were still unpacking for the gift shop. It was exciting to be one of the first - certainly nothing we expected when we set out from Lake McDonald in a jammer tour at 10:30 am. Nice, unexpected surprise. I looked back at my pics to confirm the date. I think the predicted/estimated date on the park website had been 6/20. I do know they opened the road later than the posted estimated date.
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Here are some pictures from opening day 2010. I'll leave this open to the public for a while -
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I plan to visit late July, or maybe August, or even early September. Any recommendations on when to visit? Also, for the itinerary I outlined, should it be rearranged? Can anyone suggest a "what to do" each day schedule or itinerary? Thanks!
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I suggest you read some of the trip reports. GREAT ideas!
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Have Breakfast at Izaak Walton Inn
See Goat Lick Area
Maybe stop and see Glacier Park Lodge
At Two Medicine do the Boat Tour
See Trick Falls aka Running Eagle Falls
Dinner @ St. Mary's
There is "Scope it Out" most nights with a ranger at Many Glacier--which is bear viewing thru a spotting scope
You could hike to Iceberg Lake or Ptarmigan Tunnel
(sometimes you can hike on a ranger-led tour)
Both of these are longer hikes 5-8 hrs depending on your pace
or a boat tour of St. Mary Lake or Swift Current Lake
perhaps another boat tour this morning
do the early morning bird hike with a ranger (1 hr)
Take a Historic Red Bus Tour to Waterton
Have Afternoon Tea while there at Prince of Wales Hotel
Stop at Logan Pass and do a hike their
The Premier hike is The Highline Trail, but it is long
You could hike The Hidden Lake Trail at Logan Pass
and then hike the Trail of the Cedars also
Maybe have a picnic lunch along the side of the road
I would probably opt for Lake McDonald
It can be hard to get a parking spot at Logan Pass sometimes,
so you may need to take a shuttle there from Lake McDonald
Zipline at Whitefish
or do a Helicopter Tour of Glacier before your flight out
There are also horse rides at a couple of spots
If you like adventure and hiking. I have always wanted to stay at Granite Park Chalet. This is a back country hiking Lodge spot on the Highline Trail.
Get your reservations ASAP
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I should say that I have never been to Glacier, btw.
I had a cabin booked just 1/2 mile out of Apgar through VRBO. 49 airplanes were damaged in Denver during a hailstorm. Anyway, there were no flights to be found for 4 days, so we got our money back on the airfare, but lost about $2000 on the cabin. But, we had a very similar iten as to yours. We don't have plans to go this summer, but most likely will go the next. Have a great trip!!
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Stonington gets rival Griswold in home opener
Stonington gets rival Griswold in home opener
STONINGTON — After three tough road games, the Stonington High football team makes its home debut at the new Donald E. Palmer Field's turf surface at 6:30 p.m. Friday.
The Bears said good-bye to the ECC-Small Division after rising to the Medium this season. But the defending Small-champion Bears (1-2, 1-1 ECC-Medium) have not left behind traditional Small rival Griswold.
The always-tough Wolverines (3-1, 1-0 ECC-Small) invade as Stonington's first foe on the new field in an out-of-division game.
"We always get support from our home crowd, it's youth day and we're excited to be playing a varsity game on our home field," Stonington coach A.J. Massengale said. "Griswold is a good team on many levels and has one of the best quarterbacks in the ECC."
Griswold is quite the home wrecker, winning its last three games at Stonington in 2007, 2009 and 2011. Last year, the Wolverines held the usually-lethal Stonington Double Wing rushing game to no yards in 28 attempts. Bear quarterback Divante White stepped up to pass for 204 yards and two TDs in a 28-7 Stonington victory.
Griswold is in the driver's seat to win the ECC-Small this season after nipping Windham, 21-20, en route to its strong start. The Wolverines feature one of the ECC's better passers in Seth Davis, a 6-foot-1, left-handed senior, who threw for 249 yards against Windham. Aside from the key win over Windham, Griswold has beaten Woodstock, 41-8, and St. Bernard, 26-0, of the Small, and lost to East Lyme, of the Large, 20-7.
Stonington looks to continue positive vibes from its 35-21 win against Waterford where it rushed 60 times for nearly 500 yards, led by Zach Poirier's 236 yards on 22 carries. Poirier, a senior, leads Stonington with 495 yards and is closing in on 2,000 career yards after hitting the 700-yard mark as a sophomore and 755-mark as a junior.
White also had a career-high 128 rushing yards and two touchdowns, including a 65-yard score. Stonington was so effective running, hite only attempted four passes.
Massengale gave the Bears' offensive line of tackles Ryan Francis and Ted Farrell, guards Brad Turner and Dan Crandall and center Nick Ryan their highest marks of the season, but cautioned that the team overall must cut down on its penalties. Stonington was whistled for 12 penalties for 120 yards against the Lancers last week.
"They continue to work hard and get better every day," Massengale said. "That's all you can ask for."
Defensively, Stonington produced its best effort, holding Waterford to 21 points after squandering 86 points and more than 1,000 yards rushing in early losses to Fitch and Montville. Junior defensive back Bow Johnson has already intercepted three passes, including two fourth-quarter pickoffs last week.
The Bears received more help in the form of regulars returning to action from minor injuries (nose guard Andrew Cordeiro, linebackers Harry Calmar and Jacob Shulda) and an influx of sophomores (Seamus Wallace, Julian Maiarano and Hunter Floyd) into the rotation. Linebacker Jack Riordan, lineman C.J. Dipollino and White at safety also played well.
"We did a better job tackling and communicating," Massengale said. "These are a resilient group of kids and never did I question their effort."
Warwick Vets
at Chariho, 7 p.m.
WOOD RIVER JCT. — While the young Chariho High offense gains experience and looks to break a three-game streak of scoring one touchdown or less, the Chargers face perhaps Division II-A's most experienced signal caller Friday — Warwick Vets senior Jesse Sedoma.
A three-year starter, the 6-foot-1 Sedoma leads the Hurricanes (3-1, 2-1 Division II-A) into Chariho in the fifth straight home game for the Chargers (1-3, 0-3 Division II-A). Warwick Vets has lost only to Woonsocket, 27-0, and has beaten Providence Country Day (47-21), Toll Gate (35-0) and Coventry (28-27). The one-point win came one week after Coventry blanked Chariho, 28-0.
"(Sedoma) has size, speed and experience," Chariho coach Mike Kelly said. "He's been in pressure situations many times and can read defenses and see open receivers. He's probably the best quarterback we'll face all year. He sets the tone for their whole team."
The junior-laden Chargers have scored just five touchdowns with one coming on Daniel Urena's blocked field goal return in the opening victory against Narragansett. Three Jacob Rousseau touchdown passes to end Tyler Bobbin account for three TDs. Kelly said Rousseau's development as a passer is key to open up the Charger running game, led by 225-pound Sal DeSantis (49 carries for 234 yards) and John LaMotte (15 for 104). Rousseau, a junior, has thrown for 144 yards but no interceptions.
"The team understands we have a lot of new faces that have had to acclimate to high school varsity football," Kelly said. "We're getting solid play in spurts and look to extend those spurts to longer stretches. We've had different guys step up from time to time. Adam Harvey had a good game at linebacker against Mt. Hope and that has translated into practice. Receiver Nick Ciringione has done a great job blocking. All in all, everyone is working hard and looking to get better."
On the positive side, Kelly said Chariho is relatively injury-free compared to last season when the Chargers seemingly lost a player a week from an already thin roster. The Chargers coach also hopes playing a fifth straight home game to open the season gives the Chargers an edge. In a rare scheduling quirk, Chariho's first six games are at home.
"With a young team, you would rather play at home than board a bus," Kelly said. "Not having to plan for traveling logistics is one less thing to worry about."
Westerly at Toll Gate, Saturday 10 a.m.
WESTERLY — The momentum pendulum appears to be swinging in Westerly's favor after its 0-2 start.
The Bulldogs (1-3, 1-2 Division II-A) handled Chariho two weeks ago and gave Woonsocket a scare before falling, 12-7, last week. And now they face a team which wasn't won a game since 2011.
Toll Gate (0-4, 0-3 Division II-A) hasn't tasted victory since posting a 2-9 record in 2011. Westerly coach Chris Wriedt is looking to take care of business but warns his winless opponent has mastered the art of disguise.
"They've struggled as a program, but are getting a little better," Wriedt said. "The main thing with Toll Gate is they try to confuse you offensively. They run multiple sets — at least 20. They have one-back sets, two-back sets, no-back sets, three receivers, five receivers, two receivers. We have to be prepared for anything they throw at us."
Opponents have outscored Toll Gate, 154-32. In Division II-A, Warwick Vets (35-0), Coventry (29-8) and Johnston (36-6) beat the Titans. Wriedt pointed out fullback-linebacker Chris Durand as a player to watch on a roster of 25 players.
"He's a very tough kid who plays hard all the time, regardless of the score," Wriedt said.
A concern for Westerly is replacing two-way senior starter Matt Moretta, who injured his knee against Woonsocket and will not play Saturday. Wriedt said Moretta, a tight end-defensive end, is awaiting results of an MRI and could miss at least two games.
"Joe Hill did a nice job at defensive end and Tyren Gamble gave us good production at tight end, despite never playing there before," Wriedt said.
The Bulldogs will look to generate more offense than the 150 yards a game it has averaged. Fullback Tom McGuire (52 carries for 205) yards is the leading rusher for a team that accumulated half of its 514 season rushing yards in one game against Chariho (262). Woonsocket held Westerly to 13 receiving yards and 97 rushing yards in 46 carries, including minus-34 yards on five sacks.
"We're trying to get the whole offense in stride after last week," Wriedt said. "We've made progress overall, getting a little better each week than the opener against Barrington. This improvement hasn't always equated to wins, but if we can stick that tight to a team [Woonsocket] that hadn't given up a point in Division II-A, we can't be that far behind."
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text:
Research Topics
Jessica D Payne
Affiliation: Harvard University
Country: USA
Detail Information
- The impact of stress on neutral and emotional aspects of episodic memoryJessica D Payne
University of Arizona, Tucson 85721, USA
Memory 14:1-16. 2006..These data, which are also consistent with results obtained in a number of studies using animals and humans, have implications for the traumatic memory debate and theories regarding human memory...
- Sleep preferentially enhances memory for emotional components of scenesJessica D Payne
Department of Psychology, Harvard University, Cambridge, MA 02138, USA
Psychol Sci 19:781-8. 2008..Memory for a negative scene develops differentially across time delays containing sleep and wake, with sleep selectively consolidating those aspects of memory that are of greatest value to the organism...
- The role of sleep in false memory formationJessica D Payne
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Neurobiol Learn Mem 92:327-34. 2009..While these effects produce memories that are less accurate after sleep, these memories may, in the end, be more useful...
- Stress administered prior to encoding impairs neutral but enhances emotional long-term episodic memoriesJessica D Payne
Harvard University, Department of Psychology, William James Hall, Cambridge, Massachusetts 02138, USA
Learn Mem 14:861-8. 2007..These differences likely emerge from differential actions of stress hormones on memory-relevant regions of the brain...
- Sleep leads to changes in the emotional memory trace: evidence from FMRIJessica D Payne
Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
J Cogn Neurosci 23:1285-97. 2011..Although circadian effects may have contributed to these findings, our data strongly suggest that a night of sleep is sufficient to evoke qualitative changes in the emotional memory retrieval network...
- The effect of cognitive reappraisal on the emotional memory trade-offAllie Steinberger
Department of Psychology, Boston College, Chestnut Hill, MA 02467, USA
Cogn Emot 25:1237-45. 2011..These results suggest that the cognitive process of reappraising the scenes is sufficient to reduce the trade-off effect, even when such processing leads to an intensified affective response...
- Dreaming of a learning task is associated with enhanced sleep-dependent memory consolidationErin J Wamsley
Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Psychiatry, Boston, MA 02215, USA
Curr Biol 20:850-5. 2010..That similar effects were not observed during wakefulness suggests that these mnemonic processes are specific to the sleep state...
- A brief nap is beneficial for human route-learning: The role of navigation experience and EEG spectral powerErin J Wamsley
Center for Sleep and Cognition, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Learn Mem 17:332-6. 2010..Complementing observations that learning-related brain activity is reiterated during post-navigation NREM sleep in rodents, the present data demonstrate that NREM sleep confers a performance advantage for spatial memory in humans...
- Stress differentially modulates fear conditioning in healthy men and womenEric D Jackson
Department of Psychology, University of Arizona, Tucson, Arizona 85721, USA
Biol Psychiatry 59:516-22. 2006..The present study examined the impact of acute stress and cortisol (CORT) on classically conditioned fear in men and women...
- The role of sleep in declarative memory consolidation: passive, permissive, active or none?Jeffrey M Ellenbogen
Center for Sleep and Cognition, Harvard Medical School, 330 Brookline Avenue, Feldberg 866, Boston, MA 02215, USA
Curr Opin Neurobiol 16:716-22. 2006..Although the precise causal mechanisms within sleep that result in memory consolidation remain elusive, recent evidence leads us to conclude that unique neurobiological processes within sleep actively enhance declarative memories...
- Human relational memory requires time and sleepJeffrey M Ellenbogen
Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 104:7723-8. 2007....
- Sleep, dreams, and memory consolidation: the role of the stress hormone cortisolJessica D Payne
The University of Arizona, Department of Psychology, Tucson, Arizona 85721, USA
Learn Mem 11:671-8. 2004..The concentration of cortisol escalates over the course of the night's sleep, in ways that we propose can help explain the changing nature of dreams across the sleep cycle...
- Residual effects of emotion are reflected in enhanced visual activity after sleepKelly A Bennion
Department of Psychology, Boston College, 140 Commonwealth Avenue, McGuinn 300, Chestnut Hill, MA, 02467, USA
Cogn Affect Behav Neurosci . 2016....
- The differential effects of emotional salience on direct associative and relational memory during a napSara E Alger
Department of Psychology, University of Notre Dame, 118 Haggar Hall, Notre Dame, IN, 46556, USA
Cogn Affect Behav Neurosci 16:1150-1163. 2016....
- Effects of post-encoding stress on performance in the DRM false memory paradigmEnmanuelle Pardilla-Delgado
Department of Psychology, University of Notre Dame, Indiana 46556, USA
Learn Mem 23:46-50. 2016..These results suggest that stress supports gist memory formation in the DRM task, perhaps by hindering detail-specific processing in the hippocampus. ..
- The role of sleep in human declarative memory consolidationSara E Alger
Department of Psychology, University of Notre Dame, Notre Dame, USA
Curr Top Behav Neurosci 25:269-306. 2015..Finally, we discuss the literature regarding the impact of sleep on emotion regulation...
- Sleep and cortisol interact to support memory consolidationKelly A Bennion
Department of Psychology, Boston College, Chestnut Hill, MA 02467, USA
Cereb Cortex 25:646-57. 2015....
- Laugh yourself to sleep: memory consolidation for humorous informationAlexis M Chambers
Department of Psychology, University of Notre Dame, 118 Haggar Hall, Notre Dame, IN, 46556, USA
Exp Brain Res 232:1415-27. 2014..These findings provide preliminary evidence that sleep's impact on negative emotional memory consolidation and emotional reactivity can be extended to positive stimuli as well. ..
- Sleep promotes lasting changes in selective memory for emotional scenesJessica D Payne
Department of Psychology, University of Notre Dame Notre Dame, IN, USA
Front Integr Neurosci 6:108. 2012..These results suggest that the sleeping brain preserves in long-term memory only what is emotionally salient and perhaps most adaptive to remember...
- The effects of experimentally induced stress on false recognitionJessica D Payne
University of Arizona, Tucson, AZ 85721, USA
Memory 10:1-6. 2002..This finding indicates that stress, possibly through its impact on the hippocampus and prefrontal cortex, can potentiate false memories...


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As part of its summer-long music series, Franconia Sculpture Park will host a World Music Festival on Saturday, Aug. 17.
At noon, listen to jazz sounds from Brazil, with the St. Paul duo of Mira and Tom Kehoe of Xibaba.
At 2:30, gear up for Taiko drumming by Minneapolis's Mu Daiko of the Mu Performing Arts Center.
Taiko ("big drum" in Japanese) is a dynamic art form born from ancient traditions that has evolved in North America, combining driving rhythms and movements inspired by martial arts.
At 4:30, Viviana Pintado and the Q-Band will present traditional Cuban music with influences of modern pop, Cuban salsa, bachata and cumbia.
Two bands that were scheduled to perform at the sculpture park on June 15 will make their appearance in the evening.
At 6 p.m., L'Assassins, self-described "vixen rockers," will snarl their way through the roots of garage rock and female angst.
At 8 p.m., The Chalice will present a blend of hip-hop, funk, pop and R&B.
The event is free after paying $5 for parking. Food and drink will be available for purchase at the Lizard Lounge. During breaks, take guided tours of the outdoor sculpture exhibition.
[email protected] is made possible, in part, by Minnesota taxpayers through a grant from the East Central Regional Arts Council, thanks to a legislative appropriation from the Arts and Cultural Heritage Fund.


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Spick and Span — Fashionable Keynote Template
* * * Limited time offer: -20%. Yay, Autumn! * * *
Spick 'n' Span is a stylish and fashionable multipurpose template for Keynote app. It's great to use it for your magazine layout, e-commerce or fashion project, clothing startup, sewing company etc. The template is beautifully designed and nicely animated. It includes slides for team, portfolio, magazine, products and much more. Draw attention to your product or service with Spick 'n' Span presentation!
What's in the box
- 16:9 screen size
- 5 color schemes
- 7 vector icon packs including Font Awesome
- Vector mobile and desktop devices
- Fonts
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Note: soundtrack is not included. All the goodies are located in Master slides.
- 40+ uniques slides
- Vector graphics. Easy to style and customise.
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- Great looking and legible on both laptops and big screens.
- Magic Move transitions.
Requirements: Apple Keynote v6.5+.
You may also like: Motion — Creative Multipurpose Keynote Template


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Police: Man steals boat at knifepoint, falls into Green Lake
SEATTLE -- A man's career as the pirate of Green Lake was short lived after he stole a fisherman's boat at knifepoint only to immediately be tipped into the lake last Tuesday, according to the Seattle Police Department.
According to the police report for the incident, the victim was packing up after a day of fishing around 8 p.m. when the suspect approached him holding a steak knife and grabbed his small boat.
The suspect got into the boat and started to take it to the middle of the lake when the victim flipped it over, sending the suspect tumbling into the water, according to the report.
The victim dragged the boat to his car, and the suspect reportedly came at him again with the knife.
The victim walked away from the suspect, and the suspect headed toward the Green Lake Community Center. A witness later told officers the suspect stabbed a garbage can on his way.
The suspect walked into the community center, handed the knife to an employee and said he needed help. Staff later told officers the suspect was soaking wet and appeared to be under the influence of drugs or alcohol.
The staff told the suspect to take off his wet clothes in the changing room and called the Seattle Fire Department to come help him.
Officers arrived and arrested the suspect. He was booked into King County Jail for investigation of theft and harassment.


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Separate names with a comma.
Discussion in 'Technique [BG]' started by Bassdude15, Dec 29, 2013.
The three chords I have so far are D,G#, and F# (All minor).
All advice is appreciated!
try F major?
I kind of want the song to have a sort of middle-eastern tinge to it, so please keep that in mind. Any anyone think of a Locrian chord that would not sound too dissonant with the three that I have?
So... A#7?
I second the B. it fits with the g,d and the d,f
just my .05$
You are welcome. Please credit me in the liner notes.


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Trump says NFL too worried about players' safety
"Going to the White House was a great honor until you showed up!"
Don Bauder 7:15 p.m., Sept. 23
Dourson's bold moves to tackle and disarm a man who put a loaded handgun in his face during an attempted robbery made national news in February 2011. But Dourson said he is disappointed with a plea deal the prosecutor's office made in November.
In the plea deal, Thomas Scott Ruth, 23, admitted to two counts of attempted robbery and that he had used a dangerous weapon. It was unclear if the weapon he admitted to having used was pepper spray or the loaded handgun. Five other felonies were dismissed in the deal, including assault charges for spraying both the shop owner and his employee with tear gas in the course of the midnight scuffle. Court paperwork is unclear as to whether Ruth admitted to the special allegation of using a firearm during an attempted robbery.
Both Dourson and his employee Patrick Clemons said that a man wearing a knit mask pointed a gun at them and said, "Give me the money!" Dourson claims he said, "What money?" and then was peppersprayed. Dourson made his way to the cash register; he managed to dial 911 as he passed a wall phone. When the robber began to wave his gun around, Dourson decided to tackle him. Both Dourson and Clemons said they wrestled the would-be robber onto the tiled floor and took his pepper spray and handgun. BBs and pellets spilled out of the gun. Some ammunition rolled under the nearby pizza oven.
"He kept saying, 'All right, all right, I'll just leave,'" Dourson said. "But I said, 'No, man, the cops are going to escort you out.'"
Clemons was so annoyed, he tried to pepper-spray the attacker with his own weapon, but Clemons couldn't work out how to use the can, so he threw it away.
Dourson said he pulled the ski mask off the offender as soon as they had him on the floor, but he did not recognize Thomas Scott Ruth. "Thank God it was a 22-year-old spoiled brat from La Costa and not a real criminal," Dourson later said.
The Would-Be Robber Confessed, Carlsbad Cop Said
Carlsbad police officer Shaun Lawton arrived on the scene to find Ruth restrained on the floor. "I immediately handcuffed him," he said. The officer described the gun recovered as a CO2-powered pellet pistol in the style of a Beretta semi-automatic.
After he took the bloodied Ruth away from the pizza-shop workers, Officer Lawton asked Ruth if he'd planned the crime or if it was a spur-of-the-moment decision. at a preliminary hearing, the officer testified that Ruth told him it was a spur-of-the-moment thing.
Ruth was ordered to face all seven felonies at the end of his hearing in June.
He received a moving violation while out on bail in August. He gave an address in the 3000 block of Calle del Sur in Carlsbad — this is La Costa, an upscale part of San Diego County.
Dourson now complains that Ruth has received "rich man" justice. The restaurateur, who works the overnight shift in his pizza shop every night, can't understand why the robbery case was not continued to a trial. Dourson wants the man who stuck a gun in his face and pepper-sprayed him convicted of all seven felonies he was charged with.
"The robber got a sweetheart deal," Dourson said. "I don't think that Thomas Scott Ruth thinks there are consequences for his actions. And this case is proving it." Dourson claims the plea deal was intended to be completed on October 26 — as a gift for Thomas Scott Ruth's birthday — but that because journalists got word of it, the deal was delayed.
About a month after Scott was first brought to court, the specific charge of attempted robbery against Mychal Dourson as the named victim was dropped, in an "amended" complaint filed March 30, 2011. This reduced the felony count to six. Inquiries were made, and Dourson says the district attorney's office says it was a clerical error. This "error" was corrected June 30, when a "second amended complaint" was filed, and the missing felony was restored.
"I feel completely betrayed by the district attorney's office. We didn't even get a chance in the justice system. They stole my opportunity for justice."
Dourson has had as many as ten phone conversations with persons in the prosecutor's office. "I fought for months to stop this plea deal, but it was futile, against the wishes of the DA's office."
He was told that prosecutors "cannot force the defendant to go to trial," and "there's nothing I can do," and "the decision came down from the branch chief." (A person with the DA's office said that Summer Stephan is the current chief of the DA's North County branch.)
Clemons is also disappointed. "The plea deal saddens me but doesn't surprise me much. What small faith I had in the fairness of the justice system waved its final goodbye…'cause I guarantee [that] if Ruth was poor and a minority, justice would've already been dealt — with a much heavier hand."
"This whole situation stinks," Clemons concluded. He and his boss have been friends for 17 years and have worked together making pizzas for ten. Both men were 36 years old at the time of the robbery.
It does appear that this case may have been passed around like a hot potato. In less than one year, several different deputy district attorneys have been assigned to the case, including Aimee McLeod, Christine Ryan, Brooke Tafreshi, and Brock Arstill.
At the sentencing hearing on February 2, 2012, judge Daniel Goldstein ordered Thomas Ruth to serve 365 days for each of the two felony attempted-robbery charges that he admitted; time is to be served consecutively and in county jail, not state prison. But then the judge suspended that sentence and granted the defendant three years of formal probation. Judge Goldstein ordered Ruth into a residential treatment program and to report to a probation officer within 72 hours of his release from custody. ■
At the sentencing hearing on February 2, 2012, judge Daniel Goldstein ordered Thomas Ruth to serve 365 days for each of the two felony attempted-robbery charges that he admitted; time is to be served consecutively and in county jail, not state prison. But then the judge suspended that sentence and granted the defendant three years of formal probation == The two years in county was a gift-then to see that sentence was suspended????? Whoa. There is no logical reason for that at all. THat tells me this guy knew someone, and someone who was high up and connected.
This was a violent crime, robbery (although if he had a BB gun instead of a real gun that does take it down a notch).
The guy is right, if this guy were poor, and a minority (black or brown), he would have done 10 years in state prison.
I have seen people do real time in county for a two punch fist fight.
One last thing to note, this was a violent "strike" offense, where the time given must be 85% served. I would like to know if the strike was part of the deal???
Sentencing is unbelievably complicated. I was there at sentencing, and I saw the paperwork and I am still not clear how it is that the Sheriff has the perp's release date listed as December 27 of this year. That doesn't even make 2 years since the date of the crimes, Feb 16 2011. On the day of sentencing it was noted that the perp had already served 137 days in custody but was being credited with 205 days. The same day, Feb 2 2012, Judge Goldstein warned the perp that he has "two strikes" now. Sometimes I can only report what is going on, as accurately as possible, without necessarily understanding it all.
OK, this is confusing because the story says the 2 years was "suspended". I just checked and this guy IS in custody in Vista on TWO robbery convictions. He was booked 9-22-2011 and is set to be released 12-12-2012, that is 13 months. So his sentence was not suspended. Strike offenders are not supposed to go to county jails, or "Local Prison", they are supposed to go to a state pen. I don't know how he got this deal, but 13 months for TWO robbery convictions is a gift anyway you slice it.
The CO2 powered pellet gun can be a deadly weapon. If the pellet or BB is fired near the eye socket or sinuses, for example, the projectile can easily make it into the brain. According to the victims, the perp put the loaded pellet gun into their faces before he sprayed them both with mace. That makes two dangerous weapons used on two different people, during the attempted robbery. Posted by Eva Knott.
Yes, a pellet or BB gun could in a worst case scenario cause a death, but it is so unlikely I question if they could make that stick. I guess that would qualify as "dangerous" though.
As for pepper spray, I guess it too is a "dangerous" weapon. It is not deadly, but I guess dangerous is a term that could be applied.
The entire system is a mess because the discretion is 90% of the system, where one person is sent to the slammer for 10 years for some minor non violent crime and a guy like this gets 13- 22 months of local jail. BTW, was he out on bond between the February arrest and the booking date of September??
He received a moving violation while out on bail in August. == OK, he was out on bond. So he is doing 13 months for two robbery convictions. I can't imagine they would not be strikes, except that strikes are considered violent and I thought required state prison and 85% of the sentence to be served.
But I guess this is all wheel and deal type stuff, where the judge and prosecutor can bend the rules and do whatever they want under "discretion".
Well, Thomas is my friend, and this article left out a few key details. The first one is that he doesn't even remember committing the crime. He was in a blackout brought on from the self-medication he was administering due to a serious opiate addiction. He basically stumbled into the pizza joint. His fault? Yes. The psychopathic actions of a deranged potential murderer? Hardly. He got such a light sentence because he has severe depression which went untreated, as well as a whole bunch of other psychological imbalances.
What I do know is that Thomas is honestly one of the nicest people I've ever met. He's the kind of guy who will walk into a gas station, buy a Twix bar, eat one quarter, and share the other three with whoever he is with. I've had a lot of heart-to-hearts with him and he's not a bad guy. He's actually got a genius level IQ.
Finally, that has to be the least flattering picture of him I've ever seen. He's usually smiling and friendly.
Re: Mr. Ruth, consequences, and addiction
Incarceration is not intended to be comfortable. Nor is it a benign "time out" or scolding. For someone like Mr. Ruth -- a fundamentally decent, intelligent young man -- it had to be a sobering, frightening experience. No one is the same after jail or prison. Even the "'rich man' justice" Mr. Dourson complains of did not preclude Mr. Ruth the dehumanizing, dangerous, and traumatic year in custody. Few people understand that the San Diego county jail system -- under the pressures of California prison realignment scheme -- is essentially as dangerous as any prison. Violence is the norm.
A more balanced piece (i.e., less sensational, less TMZ.com-flavored) might have included more about Mr. Ruth's mental state past and present. If it is true the he is an addict, author Eva Knott might have added this profound fact: a person will do things under the influence of substances that he simply would not ever do sober, and that some consequences of these things cannot ever be erased or amended. Felonies are an example of this.
Mr. Ruth cannot erase or amend this. Even in light last month's amendment of the "strikes" law, the two "strikes" the judge applied are profoundly serious business. Now he must rebuild a life, and no amount of wealth or preferential treatment will make the task easy.


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Various CitiesSee Registration informationDelhi, Mumbai and Bangalore, India
Risk has always been a part of the adventure of entrepreneurialism. However, in an asset class that is constrained by limited resources, how does one best assess, create and edit a concept while exposing the least amount of cash?
Luck inevitably plays a role, but as in all games of chance, there are specific skills that one may acquire to improve the odds of winning. Professor Scott Meadow's presentation will outline those analytical skills essential to developing a foundation for success in entrepreneurship.
No Charge
Register OnlineRegister for New Delhi on Friday, April 17 at http://boothinitiativesdelhi.eventbrite.com
Register for Mumbai on Wednesday, April 22 at http://boothinitiativesmumbai.eventbrite.com
Register for Bangalore on Thursday, April 23 at http://boothinitiativesbangalore.eventbrite.com
Deadline: 4/16/2009
Scott Meadow (Speaker)Clinical Professor of Entrepreneurship; Faculty Director of Global Initiatives, Chicago Booth School of Business
Since 1982, Scott Meadow has been a principal investor in the private equity industry.
Scott Meadow is the Faculty Director of Global Initiatives and since 2000 has held the position of Clinical Professor of Entrepreneurship at the University of Chicago Booth School of Business. He was awarded the 2002, 2003, 2004, and 2005 Phoenix Prize for Excellence in Teaching, the first time one has ever been so honored. He was designated by Business Week's "Guide to the Best Business Schools" (2003, 8th edition) and (2005, 9th edition) as one of the ten outstanding entrepreneurial professors in the country. Scott has taught 4000 students at Chicago Booth, in Entrepreneurial Finance and Private Equity, Commercializing Innovation (which he created) and the New Venture Challenge sections.
Scott has over 25 years experience as a general partner with four venture capital and private equity firms including William Blair Venture Partners, The Frontenac Company, The Sprout Group, and most recently with the Edgewater Funds, where he remains an Associate Partner and Advisor. Over the course of his career, Scott has approved hundreds of equity financings, been active in fundraising and has personally led, originated or created more than sixty investments including two dozen healthcare services companies, over a dozen consumer services and retail companies, as well as companies enhanced by the Internet. His IRR over his career is greater than 40%. Scott has been recognized four times by Venture One as one of the outstanding healthcare investors in the industry for creating $560 million in equity value.
Leslie Plaisted +65 9726 6154
The University of Chicago Booth School of Business |
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With the ever-increasing technology platforms and consequently burgeoning applications and softwares developed on them, software maintenance is becoming more and more crucial to maintain peak organizational and system efficiency. The core companies working on advanced technology develop high quality software that is meant to perform specific tasks. Proper maintenance of these softwares by domain professionals is vital for the success of any endeavor.
The growing need of IT industry generated various softwares to carry out the various designated functions. But generating software solution is only half done job. There arises the need for software solution that is scalable and robust so that long performance can be maintained by trouble shooting various hurdles that arise during program execution.
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Maintenance is the alteration of a software product to correct faults, improve performances of the product attributes so that to adapt the product to a new or changing demand of market and clients. Rose India provides maintenance services in application management including application maintenance, request based software services, enhancement services for third party products, and post release support. It also provides feature level and request level design and development for products, bug fixing, enhancements, operational support, and product level testing.
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Corrective maintenance: imprudent modification of software is carried out after discovered problems. At this stage we detect and correct hidden faults in the software product.
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text: The boys eat watermelon like nothing else, so when we're having a summertime celebration I always try to pick one up. The other day when I went to purchase food for our annual gathering to celebrate the start of the football season, there weren't any small-to-medium sized watermelon in sight. I purchased the smallest of the melons on hand and… Read More


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Math for Quilters Quick Reference Guide
This quick reference guide helps you find the formulas you need to create any quilt size!
With 12 pages of handy information, this guide will help you convert fractions to decimals, measure for borders, figure out yardage requirements and much more! Easily carry with you to class or on trips. It also helps you answer many of the following questions.
- What size quilt should I make?
- What about proportions?
- How much binding do I need?
- How wide should I cut the strips for binding?
- How much fabric do I need for the backing?
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Math for Quilters Quick Reference Guide
April 29, 2015
April 29, 2015
This pamphlet does not tell me what I want to know at all. What I wanted to know deals with a variety of fabrics at certain sizes developed into certain sized blocks and how much would be needed for a certain sized quilt. It doesn't even come close to providing this information. Maybe my high school math is just too rusty.


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CINCINNATI Procter & Gamble has announced plans to use renewable, sustainable, sugarcane-derived plastic on select packaging of its Pantene Pro-V, Covergirl and Max Factor brands.
The pilot packaging program will be rolled out globally over the next two years, with the first products slated to be on shelf in 2011.
Sugarcane-derived plastic is made from a renewable resource, unlike traditional plastic, which is made from non-renewable petroleum. The process transforms sugarcane into a high-density polyethylene plastic, a type commonly used for product packaging. It remains 100% recyclable in existing municipal recycling facilities.
P&G will source the sugarcane-derived plastic from Braskem SA, which manufacturers the material using ethanol made from sustainably grown Brazilian sugarcane.
"This innovation is truly consumer-driven. As we talk with women around the world, they tell us that they want to make themselves more beautiful without making their environment less beautiful," stated Gina Drosos, group president of P&G Beauty. "With this new packaging innovation, women can have confidence that their favorite brands are helping to make a difference."


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BOCA RATON, Fla. — Office Depot is extending an olive branch to its largest shareholder, Starboard Value LLP, to settle a dispute about who should serve on the company's board of directors.
In a press release, Office Depot said that if CEO Selection Committee members Tom Colligan and Marsha Evans are re-elected, the company would immediately invite to its board of directors any of the three Starboard nominees recommended by proxy advisory firms Institutional Shareholder Services (ISS) and Glass Lewis who are not elected.
Starboard is recommending its own slate of nominees for election at the Office Depot annual meeting which will be held Aug. 21. Starboard has voiced concerns about the direction of the planned Office Depot-OfficeMax merger, expected to close by the end of this year. Office Depot says that if Starboard accepts its compromise the board will increase its size, as required, immediately following the annual shareholders meeting to accommodate the additional director nominees recommended by the two advisory firms.
"We have listened carefully to Office Depot shareholders and understand that they are supportive of adding new perspectives to the board," said Neil Austrian, chairman and CEO of Office Depot. "At the same time, shareholders are also telling us that they do not want this election to impede the progress made by the CEO Selection Committee, which includes director nominees Marsha Evans and Tom Colligan. We believe that maintaining the integrity of the Selection Committee and the progress they have made are of paramount importance."


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Singer Kim Tae Woo opened up about his married life again on 'Yoo Hee Yeol's Sketchbook'.
Curious fans can't seem to get enough anecdotes about his married life. Kim Tae Woo shared, "Marriage is 50/50 in terms of pros and cons. First off, my heart becomes more comfortable, and I get to start fresh and work harder. I don't end up wasting money. But the bad thing is that I have to share the money I earn."
When the audience scowled at him for his practical response, Kim Tae Woo simply replied, "Try getting married in real-life."
Do you agree with the crooner?
Han Seo Hee makes sexually harassing comments about T.O.P during Instagram Live
14 hours ago 151,746 10,757 1,069