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B.J. Novak
Writer, stand-up comedian, actor, and producer B.J. Novak is best known for his role of Ryan Howard, the level-headed temp on NBC's top-rated sitcom The Office. He has also been a prank co-conspirator on MTV's Punk'd series, and has appeared on the big screen in Unaccompanied Minors, Reign Over Me and Knocked Up.
AppealB.J. Novak's an average-looking guy of average height and average build. While he may not stand out in a crowd based on his physical attributes, he's able to attract the attention of women thanks to his killer wit and cerebral sense of humor. Considering plenty of ladies go for serious types or macho men, there are those who do like funny, intelligent guys. Taking into account Novak's fast-growing bank account, he must have little trouble getting dates.
SuccessB.J. Novak may not be a household name, but the series that he co-stars in as well as writes for has become one of the most popular and critically acclaimed sitcoms in years. In addition to playing Ryan Howard on The Office, Novak has also been credited as co-producer, supervising producer and associate producer for the show. Some of the episodes he's scripted include "Sexual Harassment," "Boys and Girls" and "Diversity Day." The latter earned him a nomination for a Writer's Guild of America Award in 2006. The following year, he shared a WGA for Best Comedy Series. He also shared the Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Comedy Series in 2007, with cast members including Steve Carell and Melora Hardin. As a stand-up comedian, he was named one of Variety magazine's Top Ten Comics To Watch in 2003.
B.J. Novak BiographyBenjamin Joseph Manaly Novak was born on July 31, 1979, in Newton, Massachusetts, a suburb of Boston. He attended Newton South High School, where he and future co-star John Krasinski were classmates. The pair began collaborating on creative projects during their high school years, as Krasinski had a role in a play penned by budding writer B.J. Novak. They've remained friends following their graduation in 1997.
B.J. Novak went on to study languages and literature at Harvard University, earning a Bachelor of Arts degree in English and Spanish lit in 2001. During his sophomore year at the Ivy League school, he became one of the youngest editors ever of the Harvard Lampoon. Three days following graduation, he landed his first professional writing gig. Raising Dad, a short-lived WB sitcom starring Bob Saget, was filmed in Boston, and debuted during the fall 2001 season. B.J. relocated to Los Angeles around this time, with dreams of making it as a comedian.
b.j. novak the stand-up comicB.J. Novak landed his first stand-up gig not long after arriving in Southern California. With Sheelah Gobar as his opening act, he debuted at the Hollywood Youth Hostel in October of 2001. Touring the circuit of comedy venues in and around L.A., he quickly gained a name for himself as a young comic on the rise as he packed clubs like The Improv, the Laugh Factory and the M Bar. By the summer of 2002, he had earned a solid reputation as a crowd favorite, and began receiving notice in the entertainment press with write-ups in publications such as Variety.
B.J. Novak supplemented his club performances with appearances on television, including stints on Comedy Central's Premium Blend as well as Late Night with Conan O' Brien. After an MTV producer introduced him to Ashton Kutcher in 2003, he joined the ranks of the Punk'd pranksters as a chief accomplice. Some of the celebrities he had fun freaking out during the show's second season include Jaime Pressly, Usher and Hilary Duff.
b.j. novak in the officeB.J. Novak's next job proved to be his breakthrough gig. Cast as the forever apathetic temp Ryan Howard on The Office, he also serves as an occasional writer and producer of the show. Based on the British series of the same name, the U.S. version of the sitcom premiered on NBC in early 2005. It quickly proved to be a hit thanks to its talented ensemble cast and quirky brand of humor.
b.j. novak in knocked upIn 2006, B.J. Novak made his movie debut in a bit part as a desk attendant in the independent comedy Unaccompanied Minors with Lewis Black and Wilmer Valderrama. He has since appeared in bigger budget productions, playing Mr. Fallon in 2007's Reign Over Me starring Adam Sandler and Don Cheadle, and as a doctor in Judd Apatow's Knocked Up (also 2007), co-starring Seth Rogen and Katherine Heigl.
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Autoimmune Diseases
Volume 2010 (2010), Article ID 731834, 5 pages
Addison's Disease Revisited in Poland: Year 2008 versus Year 1990
1Department of Endocrinology, Centre for Postgraduate Medical Education, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland
2Department of Biochemistry and Molecular Biology, Centre for Postgraduate Medical Education, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland
Received 28 August 2009; Accepted 30 March 2010
Academic Editor: Corrado Betterle
Copyright © 2010 Anna A. Kasperlik-Zaluska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This study aimed at comparing two groups of patients with Addison's disease: A, including 180 patients described in 1991 and B, consisting of 138 patients registered since 1991. The incidence of coexisting autoimmune disorders was evaluated and etiological factors were analyzed. Immunological and imaging studies (computed tomography in group B) were performed. Adrenal autoantibodies were examined by an indirect immunofluorescence technique in group A, and by the assay measuring autoantibodies against steroid 21-hydroxylase in group B. Adrenal autoantibodies were revealed in 37% of patients examined by the immunofluorescence method and in 63% investigated by the modern technique. Tuberculosis was found in 52 patients in the group A and in two patients in the group B; metastatic infiltrations of the adrenals in CT were detected in 16 patients. Probable autoimmune Addison's disease was diagnosed in 125/180 patients (69%) in the group A and in 116/138 patients (84%) in the group B.
1. Introduction
For many years tuberculosis has been considered as the main cause of primary adrenal insufficiency [1]; however, new therapeutic methods and recent diagnostic procedures changed our view on its etiology [2]. We have been collecting and studying patients with adrenal insufficiency for over 40 years and we would like to present our experience in this matter. Our present material consists of 318 patients with Addison's disease (AD) and 301 patients with the so-called idiopathic isolated secondary adrenal insufficiency (a part of this later group was described in 1998 [3] and in 2003 [4]). In 1991 we published a report on 180 patients with AD, observed for 1 to 26 years [5]. From this time 138 new patients were referred to our department and observed for 1 to 18 years. The aim of this study was to compare incidence of autoimmune disorders and frequency of tuberculosis as well as metastatic destruction of the adrenals in these two groups of patients with AD, using more modern techniques of diagnosis in the group observed from 1990.
2. Materials and Methods
2.1. Patients
180 patients with AD, 113 women and 67 men, aged 9 to 74 years, described in 1991 (group A) and 138 patients, 97 women and 41 men, 12 to 80 years old, registered since 1991 (group B). The patients were derived mainly from Warsaw and a neighbouring area but a significant part of them was referred to our department from other, distant clinical centers. AD was diagnosed on the basis of clinical data [6] and the results of hormonal investigations. The most prominent clinical manifestations included reduced strength, fatigability, anorexia, weight loss, nausea, skin hyperpigmentation, and postural hypotension. Hyperkalaemia and hyponatraemia were frequent findings, more severe in stress situations, presenting with myalgia, joint pain, vomiting, diarrhea, and low blood pressure. The diagnostic hormonal criteria for including the patients into the groups under study were low 17-hydroxycorticosteroids (17-OHCS) urinary excretion (below 6.0 mol/24 hours, normal: 6.1–19.3 mol), low serum cortisol levels at 09.00 hours (below 209 nmol/L, normal: 209–692 nmol/L), high plasma morning ACTH concentration (more than 13.2 pmol/L, in most cases over 50 pmol/L, normal: 3.3–13.2 pmol/L), and lack of significant increase of cortisol and/or 17-OHCS in corticotropin (Synacthen) stimulation test [5]. In two patients with autoimmune origin of AD and six patients with metastatic adrenal infiltrations or lymphoma, elevated ACTH levels, 18.4 to 42.4 pmol/L were the first sign of subclinical adrenal insufficiency.
Informed consent for the studies was obtained from all the patients.
2.2. Methods
In clinical examination we searched for symptoms and signs of adrenal insufficiency; every patient was also investigated for other autoimmune disorders. The probable causes of AD were analyzed. The immunological studies, performed in all patients with probable AAD, included thyroid autoantibodies determinations: thyroglobulin (aTg) and microsomal (aMic) antibodies assayed by haemagglutination tests (normal, 1/120) and antiperoxidase antibodies (aTPO) by "in house" ELISA, as described previously [7] (normal 1/80). A search for adrenal autoantibodies was performed in 52 patients in the group A by means of an indirect immunofluorescent technique [8] while in the group B a search for antibodies against steroid 21-hydroxylase (21-OH, normal 1) and aromatic L-amino acid decarboxylase (AADC, cut off =7) in 62 patients, as well as against steroid 17-hydroxylase (17-OH, cut off =11) and side-chain cleavage enzyme (SCC, cut off =13) in 9 patients with associated premature ovarian failure (POF), was conducted by the method based on the in vitro transcribed and translated protein as described by Ekwall et al. [9]. The upper normal limit of each antibody index was established as the mean value of negative controls plus three standard deviations and values above this cut-off indicated the presence of adrenal autoantibodies. Additional hormonal measurements: thyroxine, T4 or free thyroxine, fT4, and TSH levels were measured initially by radioimmune assays (RIA/IRMA) and during the last 10 years by chemiluminescent assay (LIA). Serum estradiol and FSH were determined, if necessary, initially by RIA and during last 10 years by LIA. In selected patients parathormone, PTH was measured by IRMA. Various biochemical analyses were performed, if necessary, that is, serum glucose and HbA1c levels, calcium and phosphorus, serum and urinary values, and alkaline phosphatase activity. Computed tomography (CT) of the adrenals was performed in some patients from the group B.
3. Results
Basing on the results of the clinical examination with biochemical determinations, as well as immunological and imaging investigation, we diagnosed in the group A 125 patients (87 women, F/M ratio 2.3) with probable autoimmune etiology (69%) and 52 (26 women, F/M ratio 1.0) with a history of tuberculosis (29%). In two patients metastatic infiltrations and in one man amyloidosis of the adrenals were diagnosed at autopsy. Autoimmune disorders were found in 80 patients in the group A (64% out of 125 patients with probable autoimmune origin of AD and 44% in all the group under study). In the group B there were 105 patients (88 women, F/M ratio 5.0) with AD associated with some autoimmune disorders (76% in all the group under study), two men with tuberculosis, 16 ones (3 women, F/M ratio 0.2) with metastatic infiltrations of both adrenals (12%), four with bilateral lymphoma (two women), a 53-years-old man with bilateral adrenal cancer and 11 patients (5 women) with idiopathic AD (8%), without any abnormalities in CT (probably also of autoimmune origin). Characteristics of group A and B patients are summarized in Table 1.
The imaging pattern of CT in other examined patients, with an early stage of AAD was normal, while in two patients with tuberculous infection adrenals were enlarged. In the patients with AAD of long-term duration atrophic adrenals were characteristic in the abdominal CT.
Autoimmune diseases coexisting with AD are summarized in Table 2 (the % values are calculated for the patients with probable autoimmune AD). Thyroid abnormalities, especially hypothyroidism and thyrotoxicosis due to Graves' disease or Hashitoxicosis, as well as insulin dependent diabetes mellitus (T1DM) were dominant autoimmune disorders. In all patients with pernicious anemia atrophic gastritis (verified by histological examinations) was found, and in majority of them it was an early clinical finding characteristic of this disease. Additionally, there were two patients with chronic active hepatitis in the group A, as well as one patient with rheumatoid arthritis, one patient with a collagen disease and one patient with Dühring's disease in the group B. In two patients secondary adrenal insufficiency appeared after three and 18 years of AD duration with loss of hyperpigmentation and a decrease of ACTH concentration from 165.6 to 4.0 and from 74 to 2.2 pmol/L, respectively. Hypoparathyroidism, diagnosed as first autoimmune disorder in five patients, was associated with moniliasis. In contrast, in a young male addisonian patient (brother of a female patient with AD, T1DM, and pernicious anemia) only moniliasis was present. Multiple autoimmune disorders were observed in 20 patients in the group A (16%) and in 19 patients (17%) in the group B.
Thyroid autoantibodies were detected in 55% of the patients tested in the group A and in 65% of the patients in group B, (aMic—in 39%, aTg—in 31%, both ranging from 1/120 to 1/6480 and aTPO in 65%, ranging from 1/80 to 1/51200).
Indirect immunofluorescent method revealed adrenal autoantibodies in 19 out of 52 patients with probable autoimmune AD (37%) in the group A. Antibodies against 21-hydroxylase were detected in 39/62 patients (63%), ranging from 2 to 5000, most frequently in the patients with recently diagnosed AD (in 17 patients it exceeded 20). Antibodies against 17-hydroxylase were found in 2/9 women with coexisting premature ovarian failure, ranging 107 and 115. Anti-SCC antibodies were revealed in the same group in five patients (56%), ranging from 19 to 82. A significant level of anti-ACDD antibodies was not found in this group of patients.
A significant level of anti-AADC antibodies was not found the mortality in the group A was mainly due to the age-related diseases and the insufficiently treated tuberculosis. Four patients died because of malignant diseases: colonic cancer, ovarian cancer, uterine cancer and myeloma. In the group B, majority of patients with metastatic destruction of adrenals as well as patients with bilateral lymphoma died due to malignancy. Nearly all our patients with AAD have been engaged in professional activities or housekeeping and they have been going well at routine control examinations. To the best of our knowledge, three of them died due to adrenal crisis (insufficient replacement therapy in stress situation), intestinal perforation, and septic shock.
The routine hydrocortisone doses ranged between 25 and 30 mg daily, with extra doses if necessary, similarly as in Erichsen et al. studies [10]. In the male patients with 180 cm of height or more, a daily dose of 40 to 45 mg was necessary. The most frequent doses of fludrocortisone ranged from 0.05 mg to 0.1 mg in the morning, however in some patients only 0.025 mg has been a tolerable dosing, and individual patients withheld this drug because of oedema. In some patients 60 years old or older, we had to withdraw fludrocortisone because of the blood pressure increase induced by this drug.
4. Discussion
In this paper we present a group of 318 patients with Addison's disease registered at our department in the last 48 years. The group of patients observed till 1990 (group A) compared to the group registered in the last 18 years (group B) presented a different etiologic profile. Effective chemotherapy of tuberculosis significantly decreased the number of patients with this type of adrenal destruction, in our material from 29% to 1.5%. At present, only in the developing countries tuberculous adrenalitis remains a major etiologic factor [11]. In contrast, detectability of metastatic infiltrations of adrenal glands increased due to modern imaging techniques from 1% in the group A to 12% in the group B (together with bilateral adrenal lymphoma and bilateral adrenal cancer: 15%). In some cases of this later group we detected a subclinical AD with subtle symptoms and elevated plasma ACTH levels. In the course of further observation, clinical picture of AD developed in the patients whose tumors were inoperable.
Autoimmune disorders accompanying AD were detected in 80 patients in the group A (64% of 125 patients with idiopathic AD) and in 105 patients in the group B (Table 1). The remaining 11 patients registered recently in the group B, without any evident autoimmune disorders, according to Betterle et al. [2], could be classified also as idiopathic AD of probable autoimmune etiology. Similar observations were reported by other authors [12, 13]. Thus the incidence of autoimmune disorders in the group B could be estimated as 90% in 116 patients with probable autoimmune AD and 76% in all the patients in this group. Long-term observation of such a significant group of patients with AD revealed a tendency to development of some other autoimmune disorders (mainly thyroid autoimmunity and diabetes mellitus) in the later phases of the disease, as a sign of a progressive autoimmune process.
Our material of nonautoimmune AD in the group B did not differ significantly from the observations of Falorni et al. [14]. In contrast, in the Norwegian Registry the primary adrenal insufficiency was considered as almost exclusively autoimmune disease [10].
Conventional method of indirect immunofluorescence revealed adrenal autoantibodies in 37% out of 52 patients in the group A. Modern assays of adrenal autoantibodies detected autoimmunity in 43 out of 67 patients under study (64%). This result is similar to that in Winqvist et al. study [15].
It was characteristic that the presence of adrenal autoantibodies was detected mainly in the patients with recently diagnosed AD, while in the patients with long duration of disease, adrenal antibodies were hardly detected or absent. In our opinion lack of adrenal antigen due to a complete adrenal destruction in the long-term disease could be responsible for this finding [5]. A similar suggestion was presented by Falorni et al. [14]. It must be said however that not all our patients were characterized for adrenal autoantibodies, therefore we have to be cautious in opinion on that matter.
In previous studies we found high prevalence of thyroid autoimmunity in idiopathic AD [7], which is characteristic for autoimmune polyglandular syndrome type 2 (APS 2) [2]. In the natural history of the thyroid autoimmune disease the thyrotoxic patients developed hypothyroidism during long-term observation. Thus hypothyroidism was the most frequent, clinically overt autoimmune disease associated with AD. More than a half of the patients in the group B could be classified as having Hashimoto's disease, with presence of thyroid autoantibodies (the most frequently aTPO.). Our observations suggest an increasing tendency to thyroid autoimmunity development in AAD [16]. No significant reactivity was found against AADC though it has been shown to correlate to vitiligo [17] which was rather frequent in our patients. Antibodies against AADC were found in a significant number of Scandinavian patients [18, 19].
Diabetes mellitus and pernicious anemia were more frequent in the group B, while premature ovarian failure (POF) was a slightly less frequent disorder. Several forms of POF are not of autoimmune etiology, however in a majority of our patients with premature menopause other autoimmune disorders have been observed. The patients with hypoparathyroidism as the first sign of autoimmune disease should be classified as APS1, with different genetic background as compared with our other patients from the APS2 group.
Interestingly, we observed a conversion of two patients with AD to ACTH deficiency, probably due to development of pituitary autoimmunity.
In majority of our patients the daily dose of hydrocortisone, adjusted to their height and/or weight ranged 25–30 mg (divided in two or three doses). We are aware that such dosage exceeds slightly the normal cortisol secretion rate, but patients feel better on this dose and one cannot exclude a possibility that such a bit higher dose could delay development or alleviate the course of other autoimmune disorders. Less frequently, a dose of 20 mg of hydrocortisone was prescribed, mainly in the patients with obesity or genetically prone to obesity. Some clinical observations suggest that patients being on 15–20 mg of hydrocortisone daily do not feel fully comfortable. We cannot exclude a possibility that they present a hydrocortisone deficiency in some "substress" situations, not included in a routine stress definition. May be the oral hydrocortisone modified release tablets, mimicking the physiological serum cortisol profile, will be a better therapeutic offer for many AD patients [20].
A stable incidence of AD is suggested in the literature. In our observations however, it is the secondary adrenal insufficiency which became a more frequent adrenal disease, mainly due to the improved detectability.
5. Conclusions
() At present, in our country, tuberculosis does not play any significant role in etiology of AD. () Detection of metastatic lesions of adrenal glands increased evidently due to new imaging techniques. () Modern methods of adrenal antibodies determinations detected adrenal autoimmunity in a higher number of patients with AD than indirect immunofluorescence, more frequently in patients with AD of short duration. () Thyroid autoimmunity was the most frequent autoimmune disorder accompanying AD.
Conflict of Interest Statement
The authors declare that no financial or other relationships exist that might lead to a conflict of interest.
This research was funded by a 501-2-2-07-30/02 CMKP Grant and by EU FP7 Grant no. 201167, Euradrenal.
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subset: commoncrawl


text: On Wed, Mar 23, 2005 at 09:56:36PM -0600, Brian Mastenbrook wrote: > I've set up a daily test harness for SBCL. It builds CVS SBCL, runs a > small sanity test designed to trigger a GC, runs the regression tests, > and the ANSI tests. The index of tests is at http://sbcl.unmutual.info/ > . The tests are run under OS X (currently 10.3.8) on a 2GHz G5. > > I hope ya'll find this useful, especially as the end of the month > approaches. Any extra testing on hardware or software not available to everyone sounds useful, and few people are sufficiently ambidextrous to run the trinity of X86 classic, X86-64, and Mac. And incidentally, I'd guess that a tireless automated test is most useful earlier in the month, because at least to the extent that there's a pattern of things breaking on hardware that someone does run, I'd expect him to be motivated to run tests manually around freeze time even if he can't be bothered at other times. It might be a good idea to send email notification to sbcl-devel when things start to fail, so that people don't have to poll the site. If you set it up to send the email automatically (instead of you manually firing off a message when the issue shows up in your browser) you could avoid nagging by throttling it so that it sends no more than one message per two or three days. Throttling would also tend to minimize awkwardness when it turns out to be a nonbug, just misbehavior in your hard drive controller which happened to kick in right after you left on a canoeing trip and dropped your wireless PDA in a lake.:-| -- William Harold Newman <william.newman@...> Remember: don't show fear. Testers can sense fear. -- pfdietz


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Cleveland drops bid to host 2016 DNC
WASHINGTON (AP) - One is enough for Cleveland. The Ohio city on Friday officially dropped out of the running to host the Democrats' presidential convention in 2016. The city already won the Republicans' convention and it was unlikely the city could host both events. That leaves Democrats are considering New York City; Philadelphia; Phoenix; Columbus, Ohio; and Birmingham, Alabama. DNC Chair Debbie Wasserman Schultz is expected to announce a host city either late this year or early in 2015. Two of the leaders of Cleveland's convention bids, Cleveland Mayor Frank Jackson and former Plain Dealer publisher Terry Egger, say the DNC should pick Columbus.


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Toronto Film Festival's British Invasion
The British are coming. And this year they are coming in droves to the Toronto Film Festival.
The British are coming. And this year they are coming in droves to the Toronto Film Festival.
This smug but effective middlebrow crowdpleaser shrewdly mines its real-life material for laughs and righteous anger as well as tears.
HONG KONG – The British Broadcasting Corporation (BBC) has licensed 65 hours of TV shows to Chinese state TV broadcaster China Central Television (CCTV). The deal was announced Wednesday at the third…
LIVERPOOL — "A Young Doctor's Notebook," starring Jon Hamm and Daniel Radcliffe, could turn out to be just what the doctor ordered for BBC Worldwide. The distributor has secured six sales of the U.K…
BBC Worldwide is partnering with in-theater advertising company Screenvision to bring Daniel Craig-narrated nature docu "One Life" to Stateside theaters for a limited engagement on Feb. 21.
The British royal family's film collection is to be digitized in a joint venture between the British Film Institute and the BBC.
Off the back of positive reception for Rufus Norris' "Broken," which opened Cannes Critics Week, BBC Films has unveiled its new productions, including Saoirse Ronan starrer "Testament of Youth."
"Harry Potter" director David Yates is teaming up with the BBC to turn its iconic sci-fi TV series "Doctor Who" into a bigscreen franchise.
The BBC Trust has called on its filmmaking arm, BBC Films, to increase awareness of its work among license fee payers in Blighty.
Seasoned BBC Films topper Jane Wright is quitting -- just one year after being appointed the outfit's managing director.
BBC Films has acquired the bestselling Chris Cleave novel "Little Bee," and Nicole Kidman has attached herself as star and producer.


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A severe leg injury early in his senior year was not enough to deter Houston (Texas) Northland Christian's Justin Webster from achieving his goal of playing high-major college football.
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Greek President Holds Discussions with Syrian Vice President
The visiting Greek President Costis Stephanopoulos held on Sunday talks with Syrian Vice President Abdelhalim Khaddam on the latest international developments and the aftermath of September 11th attacks, said agencies.
Syrian presidential spokesman was quoted as saying that the two sides "tackled the situation in the Middle East area and the role of Israel in hindering peace process by its non-adherence to the UN resolutions and its constant aggressions and atrocities on Palestinians."
On Saturday, President Stephanopoulos held talks with Syrian President Bashar al-Assad on the main causes in the region and the world topped by the deadlocked Middle East peace process.
Assad said that the Israeli anti-peace government led the peace process to this deadlock and stressed that Syria wants peace and has no conditions except the adherence to UN resolutions and land-for-peace principle.
For his par! t, the Greek president said that his country supports the legitimate rights of the Palestinian people through establishing their independent state.
Stephenipoulos said that true peace cannot be achieved unless all parties respect the UN Security Council resolutions 242 and 338 and when the occupied Golan Heights return to Syria. (albawaba.com)


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Tuesday, September 26, 2017
Addiction and Substance Abuse
Alcohol abuse
my husband drinks brandy straight and chases it with a beer 7 days a week from sunup to sundown. Can this cause a bacteria infection. he has swelling in his testicles and pressure in his lower stomach and constantly going to the bathroom to urinate. he went to the doctor, he was told there was a probability that he had chlaymadia, he called the next day for the results and was told that he did not have chalaymadia but that he had a bacteria infection. Can his heavy drinking cause this problem, also, his white cell count was very high. Can the alcohol be contributing to this problem. Thank you for any information you can give me. His drinking problem causes him to be very negative and vulgar, it also seems that he can`t make up his mind on something it seems to change from one second to the next.
Alcohol and drugs of abuse weaken the immune system and consequently make the person more vulnerable to acquire infections. However, alcohol, as a substance itself, does not cause infection. I would recommend that this issue be brought to the attention of the physician (s) providing care for your husband.
Thank you for using NetWellness.
Omar Elhaj, MD
Clinical Assistant Professor of Psychiatry
School of Medicine
Case Western Reserve University


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2014 Junior 4-H Camp
Sunday, July 13 – Thursday July 17, 2014, Registration deadline May 30, 2014.
Junior 4-H Camp is a 5 day, 4 night overnight camp for youth aged 9-13 held July 13-17, 2014 at the Northern Virginia 4-H Educational and Conference Center in Front Royal, VA. Campers have the opportunity to pick roommates and are then placed in a room with campers of similar age. Each room is part of a Pack involved in different contests on various days and awarded for spirit and participation. Each day, campers go to three different classes that they choose prior to arriving at camp. There is free swim and recreation time each day, as well as evening programs and a campfire. The camp fee is $305 and includes meals and lodging, class supplies, a t-shirt, and transportation to and from Front Royal to the Government Center. Applications are due May 31, 2014 to the Extension office located at 12011 Government Center Pkwy, Suite 1050, Fairfax, VA 22035.
Contact Amy Ordonez 703-324-5369, TTY 711, or e-mail email@example.com for more information.
Fairfax County is committed to nondiscrimination on the basis of disability in all county programs, services and activities. Reasonable accommodations will be provided upon request. For more information, call 703-324-4600, TTY 711.


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hair test
Flash Draw Created Feb 21, 2008 470 x 338px Unless noted Copyright 2008 LittleHumble.
We encourage you to submit a comment and let the artist know what you think of this drawing. Please log in or join to post a comment.
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brenda1298 Feb 21, 2008
OOooo nice!! I would never have the patience to do hair like that!! 10/10
brenda1298 Feb 21, 2008
thank you for the comment. ^-^
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12-in x 144-in White Soffit
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National Ballet of Kosovo Announces 45th Anniversary Season
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Bare Feet is a 3-time New York Emmy® Award-winning travel and dance series. The show follows executive producer, dancer, and host Mickela Mallozzi, as she travels throughout different parts of the world. What makes this show unique, is that she features, discovers, and highlights the rich dance and ... (more...)
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BalaSole Dance with Guest Soloist Miki Orihara Comes to BAM Fisher, 6/2-6/3
by BWW News Desk - May 05, 2017
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Chita Rivera to Receive 'Woman of Valor Award' from Victory Dance Project, 6/15
by BWW News Desk - April 25, 2017
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by BWW News Desk - March 30, 2017
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LET'S DANCE INTERNATIONAL FRONTIERS Announces Dance Festival Lineup
by BWW News Desk - March 08, 2017
LET'S DANCE INTERNATIONAL FRONTIERS is the dynamic annual dance festival in Leicester which has been performing to increasing audiences since its inception in 2010. This year's event – April 29th-May 13th - features an extensive, exciting programme designed to give audiences the opportunity of see... (more...)


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Since 1973, three Prince William County police officers officers have died in the line of duty. Paul "Pete" White died in 1973 when his cruiser crashed as he responded to an auto accident. In 1990, Officer Philip "Mike" Pennington was shot while executing a search warrant. In 2012, Officer Chris Yung died when his motorcycle crashed as he was responding to another accident.
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From £210 per person per month This purpose-built centre is situated close to the town centre of Fraserburgh offering modern and affordable office accommodation on flexible lease terms from 1 month to 3 years. Ample car parking is available on site fo... click here for images, map, street view and more