text:
Ultrasonic Sensor, NPN/PNP, 77mm, 18mm dia.
TELEMECANIQUE SENSORS| Zoro #: G2140643| Mfr #: SM650A31600FP
Zoro #: G2140643Mfr. Part #: SM650A31600FP
$410.00 /ea
This item ships free. DetailsStandard ground shipping
Technical Specifications
|Zoro #: G2140643 Mfr #: SM650A31600FP
|Standards: UL, CE, ROHS
|Case Material: Plastic
|NEMA Rating: 4X
|IP Rating: 67
|Diameter: 18mm
|Response Time: 4.0 msec
|Power Required: 12 to 24VDC
|Operating Temp. Range: 32 Degrees to 140 Degrees F
|Output: NPN/PNP
|Description/Special Features: Fast Response Time
|Width: 0.64"
|Electrical Connection: 4 Pin M12 Male Connector
|Length: 3.32"
|Operating Frequency: 500 kHz
|Item: Cylindrical Ultrasonic Sensor
|Detecting Distance: 77mm
|Circuit Type: NO
|Max. Load: 50mA
|Country of Origin (subject to change): United States
Product Description
Cylindrical Ultrasonic Sensor, Case Material Plastic, Diameter 18mm, Detecting Distance 77mm, NPN/PNP Output, Circuit Type NO, Max. Load 50mA, Electrical Connection 4 Pin M12 Male Connector, Length 3.32 In., Width 0.64 In., Power Required 12 to 24VDC, NEMA Rating 4X, IP Rating 67, Operating Frequency 500 kHz, Standards UL, CE, RoHS, Operating Temp. Range 32 Degrees to 140 Degrees F, Description/Special Features Fast Response Time


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New lighting and new paint are part of Great Dane's program to update the company's branches.
FOR Great Dane Trailers, the good news is that some of its branches have been serving their markets for decades in the same location. But even well built trailers and the buildings where they are sold eventually require some TLC that goes beyond routine maintenance.
To make sure that these facilities continue to meet customer expectation, Great Dane is in the middle of a multi-year program to keep the company's network of factory branches looking their best.
"Our goal is to refurbish all of our locations," says Brandie Fuller, Great Dane vice-president. "Our plan is to do one or two branches a year. It's a modernizing process. Some of our locations have been serving customers for 40 or 50 years. We have been analyzing what each branch needs to serve its marketplace."
Parts and service have been a focal point, but Great Dane is looking at the entire facility, including the offices and the yard, to make sure that they are at the level they need to be. As part of the program, Great Dane has upgraded yards, expanded trailer parking, installed scaffolding and other safety equipment, updated signage, and in general made their branches safer, more efficient, and a better place for customers to do business.
The program began a couple of years ago with the Atlanta branch. Great Dane followed with its Columbus, Ohio, location in 2010.
The Indianapolis branch is the most recent facility to be updated. The bulk of the work was completed at the end of 2011, but a few features such as shelves for the parts showroom, were added as recently as September.
The Indy project was much more than a fresh coat of paint. As a result of the renovation, the branch now has an improved showroom, along with expanded storage that enables the parts warehouse to handle additional inventory.
The redo also included a newly designed office layout that does a much better job of traffic flow. In a sense, buildings reflect how a business or industry has changed through time. Since the branch was built at a time when dealers received fewer visitors, customer traffic patterns were not as important as they are today. The new office layout provides clearer paths for customers to take to go where they need to go within the facility.
Let it be light
Research has shown that employees are more productive with improved lighting. Great Dane has replaced obsolete light fixtures throughout the building so that parts personnel can find things more easily and shop technicians are better able to see what they are doing.
The branch also has new surfaces to replace materials that have fallen out of favor.
"We tore off the paneling and got down to the studs," says Andy Randall, branch manager.
The dark paneling, once popular in private homes as well as commercial buildings, has been replaced with lightly painted drywall. That alone improved lighting without requiring Great Dane to power an additional light bulb. New energy efficient light fixtures also improve lighting conditions while lowering the light bill.
Making minor changes
Minor changes to the parts department have made a difference with customers.
"We have added some shelving in our display area, but the main effect of the changes has been cosmetic," says Mike LaFary, parts manager. "When customers come in now, they see a fresh, clean appearance. New floor, new walls, a brighter look."
The update program also included an additional place to store parts. A new canopy has been added to the back of the building, providing weather protection for parts that otherwise would be directly exposed to the elements. Great Dane stores a variety of parts underneath this canopy, including steel wheels, axles, dolly legs, and trailer subframes.
Offering it all
The Indianapolis branch offers the full line of Great Dane products.
"We have a pretty wide area," Randall says. "We go as far west as Danville and Kankakee, Illinois, and as far east as Louisville, Kentucky."
The branch believes in selling face-to-face. The Indianapolis location has three people working the parts counter and two in outside sales. Nine people total are involved in parts sales and support, including one parts delivery driver who serves the local market and another who serves more remote customer locations.
"We serve the Richmond, Indiana, area on Tuesdays," Randall says. "We go to Fort Wayne (northern Indiana) Wednesdays, Jeffersonville (across the Ohio River from Louisville, Kentucky) on Thursdays, and Rensselaer (northwest Indiana) on Fridays. On Mondays, we go to Terre Haute one week and Evansville the next."
And if parts customers need it right away, the warehouse ships immediately — or the outside sales.
For the outside sales tandem, coverage is simple. One handles customers north of Interstate 70; the other goes south.
Letting people know
Great Dane got the word out about the fresh look of its Great Dane branch, sponsoring an open house June 26 that attracted more than 300 people.
The event, which ran from 4 to 7 p m, featured barbecue, a local band, and a 60-ft × 120-ft tent filled with exhibits by Great Dane suppliers.
"We were very pleased with the results," Randall says. "Our vendors were happy with the contacts they made, and it produced new opportunities for us with our customers."
The crowd left that night having seen for themselves the new look at the Great Dane branch in Indianapolis.

subset: commoncrawl


text:
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Forgot your password?
"Maybe Neymar is the best player of the world, but only if we clarify that Messi is from another planet." -- Diego
Maradona calling Pele "stupid" for his assertion that the young Brazilian Neymar, not Lionel Messi, is the
best player in the world today. (Buenos Aires Herald) ...More


text:
At the border between the Dauphiné and Provence, the Drôme Provençale will seduce you. Here, fields of lavender, sunflowers and olive orchards mingle perfectly. Discover this unique landscape staying at the Yelloh ! Village Les Ramières.
Wooded campsite near the river of Eygues, it welcomes you with family or friends in a relaxed family atmosphere. His sense of hospitality, its natural setting and good ambient mood make it the perfect destination. Stay in one of its quality accommodations, or sit on one of its sites, you will enjoy a magnificent panoramic view of the valley.
Your camping holiday in the Drôme you many surprises ! Discover Nyons, country of lavender and olive trees, or Vaison la Romaine, known for its Roman ruins. There is no doubt, your camping holiday in Les Ramières will be unforgettable !


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I'm really excited to announce SQL Pass Turkey Chapter (I'm proud to be in the leader team) is organizing 3rd SQL Saturday Community Event in Istanbul.
SQL Saturday #258 will be held on 5th October at Microsoft Office. This time we also have a fully dedicated Windows Azure track as well.
On 3rd SQL Saturday we have 25 different sessions on 5 different tracks
- SQL Server 2014
- and Windows Azure
delivered by 20 different speakers (9 international speakers, 4 MCMs, 8 MVPs and 7 MS Engineers) from UK, Portugal, Ukraine, Russia, Germany and so on.
This event is an amazing output of collaboration and efforts of many people, I really want to thank them all.
Please use #SQLSatIstanbul twitter hash tag for follow-up and questions.
Due to high demand, registrations has been closed by two weeks ago and we can only accept registrations for the waiting list at the moment http://www.sqlsaturday.com/258/register.aspx.
You can see the full schedule at http://www.sqlsaturday.com/258/schedule.aspx.
Speaker T-shirts are on my desk now waiting for their owners, really funny.
You can also follow my activities @umitsunar, and blogs by FeedBurner


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Funding will allow for production and new product development of argon-gas innovations
Ogden, UT (December 12, 2009) — Klymit, an innovator in outdoor technology, has received nearly one-and-a-half million dollars as part of a $2.2 million dollar investment from Level 4 Group, a consultant and investor specializing in defense, security and public safety products and technology.
"Level 4 Group has been talking with Klymit over the past year and after fully evaluating the unique aspects of their product set, we are truly enthused to be a part of the Klymit team," said David Kervin of Level 4 Group. "Klymit's cutting-edge insulation technology provides a solution that is warmer, thinner and lighter than other apparel and structure insulators and is something we feel has game-changing potential in the defense markets."
"Klymit is honored to work with Level 4 Group," stated Nate Alder, President and CEO of Klymit. "Level 4 Group has demonstrated a clear commitment to our game changing innovations, and because of their backing we are able to focus on developing and delivering the best products possible. We are happy to have found such a great strategic investor with smart money' that brings a lot of added value to an innovative growing company and joining our local angel investors that continue to do the same."
Klymit NobleTek insulation is the only technology on the market that gives users the power to "Kontrol the Elements" and adjust their level of warmth via flexible, gastight yet breathable chambers filled with gas instead of down or fabric. This cutting-edge technology provides insulation that is not only adjustable, but warmer, thinner and lighter-weight than other insulators. NobleTek insulation is available now in the Klymit Kinetic vest, and can be incorporated into nearly any outdoor product that uses traditional insulation, instantly making gear warmer, thinner, lighter and more versatile with adjustable insulation.
Level 4 Group is a consultant and investor in the defense, security and public safety space and assists product and technology-based businesses with the creation, analysis and execution of their business plans, with get-to-market and commercialization strategies and with sales and growth acceleration, both domestically and internationally. For more information, please visit www.level4group.net.
Klymit is a company based in Ogden, Utah that develops and licenses noble-gas-based, variable insulation technologies to companies across a variety of industries. Klymit NobleTek Insulation is the only technology on the market that gives users the power to Kontrol the ElementsTM and adjust their level of warmth with the turn of a dial. The noble gases used in Klymit's technologies are non-toxic, non-flammable, and safe for the environment.
www.klymit.com – www.facebook.com/klymitnobletek - www.twitter.com/klymit


text:
Klarus XT11 Flashlight - CREE XM-L2-U2 LED - 1060 Lumens - Uses 2 x CR123A or 1 x 18650
- Item #: KLARUS-XT11-XML2-U2-OPT
- Brand: Klarus
Request a Volume Quotation
Battery Junction 30 Day Warranty
Every Order Ships Directly From The United States
Authorized Dealer For All Products Sold
Klarus XT11 LED Flashlight
With up to 1060 Lumens of brightness, it's the ideal flashlight for daily and emergency situations!!!
The Klarus XT11 LED Flashlight demonstrates superior performance through daily use and in emergency situations. Able to run on either a single 18650 battery or a pair of CR123As, the tactical LED flashlight can produce up to 1060 Lumens that can last for more than 2 hours. With a max beam distance of 241 meters, the XT11 LED creates vision in any situation. It leads adventurers to campsites and not so lone prairies in the distances. Through the woods, the CREE XM-L2 U2 LED bulb focuses in on the active nightlife of nature, feeding up to the second information to XT11 users. The flashlight comes with holster, lanyard and body clip for easy storage and access in emergency situations.
Rugged Construction
Built to withstand tough environments, the XT11 withstands the pressures of hard, daily use.
The Klarus XT11 LED searchlight protects against falls thanks to a sturdy body built with anodized aluminum. The light's bezel is made from stainless steel, protecting the powerful CREE XM-L2-U2 bulb inside. The glass lens is toughened to survive rough, daily use. The XT11 LED Flashlight is waterproof rated at IPX-8 standard, providing functionality underwater up to 2 meters (6.6 feet).
Outstanding Advantages
The Klarus XT11 LED hunting light is mountable, removable and ready for use in every capacity.
The XT11 can be used in a variety of ways. Ideal for hunting, the XT11's easy access tailcap can switch between brightness modes to adjust to every situation. The bezel removes easily, allowing filters to be placed on the LED flashlight for enhanced hunting performance. In self-defense situations, the XT11's strobe setting can blind assailants with over 1000 Lumens of light. This will allow users to escape any danger they might encounter. Strobe functions are also helpful for location purposes, lasting up to 7.5 hours on a single charge.
- Hard-anodized aluminum body is extremely durable
- Stainless steel head pressure ring design for improved fall resistance
- Dual tail switches for one-handed operation
- Forward tactical main switch for temporary activation
- Detachable head
- Available with either black or gray bezel
- Included Accessories:
- 1 x Lanyard
- 2 x Spare O-Rings
- 1 x Spare Tailcap Boot
- 1 x Stainless Steel Pocket Clip
- 1 x Tactical Cigar Ring
- Power Source: 2 x CR123A OR 1 x 18650
- IPX Rating: IPX-8 (Waterproof and submersible up to 2 meters)
- Impact Resistance: 1 meter
- Brightness Outputs (Using 2 x CR123A):
- High - 1060 Lumens - 2 Hours 30 Min.
- Medium - 302 Lumens - 6 Hours 12 Min.
- Low - 17 Lumens - 145 Hours
- Strobe - 1060 Lumens - 7 Hours 30 Min.
- Brightness Outputs (Using 1 x 18650):
- High - 1000 Lumens - 2 Hours 30 Min.
- Medium - 251 Lumens - 6 Hours 12 Min.
- Low - 14 Lumens - 145 Hours
- Strobe - 1000 Lumens - 7 Hours 30 Min.
- Peak Beam Distance: 241 meters
- Peak Beam Intensity: 14538 cd
- Dimensions:
- Length - 5.9"
- Head Diameter - 1.37"
- Body Diameter - 1.0"
- Weight: 4.66 oz.
|Runtime (Hours):
|Output Modes:
|3+ Brightness Levels, Strobe
|Compatible Batteries:
|1 x 18650, 2 x CR123A
|Batteries Included:
|Included Accessories:
|Holster, Lanyard, Spare O-ring(s), Tactical (Cigar) Ring
|Flashlight Usage:
|Emergency Supplies, Every Day Carry, Search, Tactical, Worklights
|Throw Distance (Max):
|Switch Location:
|Product Certifications:
|Battery Junction 30-Day Warranty, Klarus 5 Year Warranty
|Return Policy:
|Battery Junction Return Policy
|Primary Material:
|Product Weight:
|Product Dimensions:
|5.9" (L) x 1.4" (Head Diameter)1" (Body Diameter)
|Country of Origin:
Klarus XT11 Flashlight - CREE XM-L2-U2 LED - 1060 Lumens - Uses 2 x CR123A or 1 x 18650
Poyntelle, PA
5 Stars
I would recommend this item to a friend.
HELP!!! i CAN'T STOP BUYING THESE LIGHTS.
July 12, 2016
I have owned three of these lights (820 lumen versions) for a few years, two as weapon lights and one in the car. When I saw Klarus now offers them with 1060 lumens I had to buy one. The 30% increase in brightness is very noticeable which made the purchase worthwhile for me. On the new version the tailcap switches are more prominent, making them easier to locate with the thumb. Other than that they are indistinguishable from the older versions. They still have spring contacts on both ends which I think is necessary for shock protection when used on a weapon. I have one on a 12 G. pump and it has survived several dozen shots with no problem. The two-switch tailcap is easy to use but be aware that the light always comes on in the brightest level; remember, this is a tactical light. The light has a wide and deep orange-peel reflector which gives a good balance of spot and flood. One thing not mentioned in the manual is that the light will start to act erratically when the battery is low, but a fresh battery fixes that. Bottom line: I like the latest version of this light enough that I just ordered another one.
Tony Kerr
5 Stars
I would recommend this item to a friend.
Excellent customer service
August 29, 2017
Bullet proof flashlight, I use every day. I'm more impressed by the customer service department, who kindly listened to a concern I had about a previous product, They took it back tested it but could not replicate the issues I was finding, With out fuss or additional monies except for a small packaging fee they sent me a brand new one. Hooked, I'm all in, they have a loyal customer, they have my business.
ricardo valdes u s veteran - dhs former officer
miami dade florida
5 Stars
I would recommend this item to a friend.
klarus XT 11 Flashlight 1060 Lumens
December 16, 2016
Another great product presentation by the team that i rely upon for the products i like. This is my third Klarus flashlight and this light is bright and designed wirh a neat mode switch that is easily accessible next to the tail cap switch boot and below. The tough aluminum body speaks volumes too fir it has a solid built, the lens is also a well made. Wirh the optional operation of cr123 s or a single 18650, this first.class product will be a winner to you just like the team who handles it for you in your order, the Battery junction customer service team. Order yours today.!
Pros:Exceptional quality, great brighness, tough body design, battery usage options.
Nova Scotia, Canada
5 Stars
I would recommend this item to a friend.
Well made and bright.
April 15, 2016
I have been using this light for over a year now for General Duty Policing. It is a great light. Solid, well made. Bright. Compact. I bought two rechargeable batteries, one for the light, one for my vest in case I am out in the back forty away from my vehicle and the battery dies. I do find the batteries last well but If you buy rechargables, buy the highest mAh you can buy. It does make a big difference. I certainly will by another one of theses.... if I ever have to replace this one.
Pros:Bright, three light settings, compact, tail cap switch, good run time on good quality batteries.
Cons:Non yet.
Mims, Fl.
4 Stars
I would recommend this item to a friend.
Klarus XT11
April 11, 2016
The XT11 has good balance and ergonomics. The mode switch next to the tail cap is a great idea. The only downside is that the light always reverts to 'high' when it is turned on, even if the mode was 'low' when it was turned off.
Bobby Wilson
New York
5 Stars
I would recommend this item to a friend.
Great Bright Flashlight
February 16, 2016
Very Bright, I love the duel switch on the back as my thumb doesn't bend the way it used to, great flashlight !!!
otisville, NY
5 Stars
I would recommend this item to a friend.
XT11 light
December 22, 2015
Very bright, well built, Overall a very good duty or tactical light.
Mark E Day
United States
5 Stars
I would recommend this item to a friend.
Nice Upgrade
December 5, 2015
I got this today and have been playing with it the last few hours. If you like the 820 you'll enjoy this one more, it has a nice black finish, glass and reflector is super clean and free of dust. It has a little more throw and the beam is nice and wide with the op reflector. Its going on my ar, that's what I bought it for, close to medium range, a bright white, smooth wide beam, in my opinion for home defense its a good choice.
Pros:Small, powerful, seems durable.
Cons:None so far, I'll update if I have a problem.
Titanium Innovations CR123A (12PK) 1400mAh 3V 3A Lithium Primary (LiMNO2) Button Top Photo Batteries - Box of 12, Shrink-Wrapped in Pairs$12.00(223 Reviews)As Low As: $10.86 Ea.Free Shipping Over $50!
Nitecore Tube USB Rechargeable LED Keylight - 45 Lumens - Built-in Battery Pack - Black, Blue, Clear, Green or Pink$9.90(142 Reviews)Options AvailableFree Shipping Over $50!
Niteye MSA10 Compact LED Flashlight - 160 Lumens - Uses 1 x AA$54.75(15 Reviews)Free Shipping Over $50!


text:
A fire broke out at a home in north Nashville late Thursday night.
The police were called at 9:25 p.m. to the 4000 block of Meadow Hill Drive.
Officials said that three people were inside the home when the fire occurred, a married couple and their 4-year-old daughter.
The father was cooking when items on the stove caught fire.
The family tried to get the fire in control, but were unable to do and called the fire department.
They were then able to escape unharmed.
When the fire department arrived, they witnessed heavy smoke and visible flames.
It took a total of 20 minutes to put out the fire.
The damage was contained to the rear of the home.


text:
New Delhi, July 21(ANI): The ruling Congress party said today that the country is prepared to face any kind of incursion from China, after the latest and recurring reports of the neighbouring forces entering into Indian territory emerged in the media.
According to reports, Chinese troops crossed into the Indian territory of Kashmir on two days (July 16 and July 17), and carried placards that asked the Indian forces to leave the 'occupied territories'.
The latest round of incursion committed by China comes a month after Indian Defence Minister A.K. Antony visited Beijing, where the issue was discussed in the bilateral talks.
Commenting on these reports, the ruling Congress party spokesperson Meem Afzal said that incursions were not novel and that India is completely prepared to combat any untoward situation at the border.
"There is always something happening at the border. It is nothing new. This happens with our border with Pakistan also. They are solved in the bilateral meets and talks. The incident, which you are talking about, is being reported in the media but I don't have proper information about this. The Defence and Foreign ministries can talk better about it. I believe that our country is strong enough that we need not fear anybody in this world," Afzal said.
Analyst Bharat Verma had said in New Delhi earlier today that China is aware that India is presently vulnerable and weak, commenting on the probing attacks on India by Chinese troops. He also said that the recurrent incursions by Chinese troops were a "prelude" to an upcoming war between India and China.
"Their calculations are that India can become very strong in coming times. They know (that) New Delhi is in no position today. There is a political paralysis in leadership. They are in no position to attack or counterattack China", Verma said.
Air Marshal (Rtd.) A.K. Singh also commented on the tension between India and China, saying that the two countries have had a tense history with regard to border demarcation and China has continually "needled" India. He suggested that the Indian leadership should continue to raise the issue.
"Certainly, India should continue to raise the issue and international polity is also aware of the Chinese agenda and the Chinese propaganda", Singh said here toady. (ANI)


text:
The U.S. Department of Agriculture has awarded more than $9 million in farmers market promotion grants.
Agriculture Deputy Secretary Kathleen Merrigan said in a news release that the awards went to organizations in 39 states, the District of Columbia and Puerto Rico for efforts to boost the connections between growers and consumers.
"This year's Farmers Market Promotion Program awards are diverse and illustrate the many different ways farmers are directly connecting to communities and consumers," Merrigan said in the late September release. "From starting up mobile markets to helping new farmers and ranchers, these grants will create new economic opportunities and encourage consumers to eat healthier."
The grants included:
- More than 40 projects starting new markets and retail outlets, community-supported programs or market season extensions;
- 17 projects supporting new delivery approaches such as online and mobile markets;
- 13 projects increasing support and opportunities for beginning growers; and
- 10 projects helping hospitals and health care groups marketing local produce.
Since 2006, the Farmers Market Promotion Program has awarded more than $32 million.


text:
Salim Refas eBooks
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Why Does Cargo Spend Weeks in Sub-Saharan African Ports?
Gael Raballand & Salim Refas
World Bank Publications, April 2012
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text:
PopMatters home | short takes home | archives
Soltero, Hell Train (self-released) Rating: 7
In last year's The Tongues You Have Tied, Soltero's Tim Howard explored the songs of seclusion. For Hell Train, he opens up the door and lets the weather in. There are some moments of pure lightheaded pop (the jangly McGuinn guitar of "Hands Up", the luscious backing vocals in "Songs of the Season") and even some unexpected acknowledgements of pop's royalty ("The Prize" recalls both "Getting Better" and Pet Sounds in a mere matter of seconds). Howard's still the sardonic bard of black-humored lovesickness and discontent; "Another year wasted alive / Will you ever be filed in the celestial archive?" and "The obvious cure for a lifetime of pleasure / Is the lifetime I'm living with you" are but a few of his choice lines. But hearing his songs shaking the winter off their backs is almost like hearing Soltero for the first time -- they're unmistakably Howard's, yet uncommonly welcoming to dense arrangements and blustery sonic abysses. "Bleeding hearts, pull together," Howard implores in "Bleeding Hearts", "And never talk about how we've given up on it all / And never talk about how far we've got left to fall". This precedes a climactic confluence of noise and metallic howls; the bleeding hearts are either drowning in their reverb-lacquered sorrows or rising from them. You root for the latter. [Hell Train is currently available only in a limited edition pressing of 500 hand-numbered CDs at Soltero's website.]
Zeth Lundy
The Cloud Room, The Cloud Room (Gigantic Music) Rating: 5
You can be sure of this: The Cloud Room is the best album ever buy a guy who was screwed out of a job working for cult indie film director Hal Hartley. That's the case with The Cloud Room's leader, J. Nice angle! Hartley's loss is a gain for fans of broad, melodic, New Order-influenced rock everywhere. The guitars are jagged and sinewy, the rhythms are disco-danceable, the vocals are somewhere between Bowie and Tom Verlaine, and the lyrics are of the "the world is so messed up; I don't know what to make of it but it's also pretty cool" variety. "Hey Now Now" is so relentlessly catchy you just give up. "Sleep in the Ocean" is a jangly, midtempo, Sumneresque number; while "The Hunger" employs Devo's clinical electro pulse. At times it's unnerving and too tense, but J's pop-art ambition is to be applauded.
John Bergstrom
The Get-Outs, Get the Message (Avebury) Rating: 6
From all appearances, The Get-Outs seem to have taken the same path of mediocrity that their label-mates Twinkie took. Juvenilely dystopian song titles like "Drowning" and "Temporary Suicide" and the initially uninteresting music contributed to this impression. However, upon further hearing, this reviewer is pleasantly surprised. Although still not producing any epiphanies, the pogo-stick energy and infectiousness is rather impressive. Amidst the noise, there is a hint of cerebral activity that can be read in between the lines of melody, showing virtuosity in arrangement and tone unrivalled by most three-power-chord punk bands. I am happy to report that Get the Message doesn't shit on the grave of the Ramones and the Buzzcocks. In fact, the Get-outs have adorned those tombstones with pretty pink punk flowers.
Kenneth Yu
Scott Hamilton, Back in New York (Concord Jazz) Rating: 7
Scott Hamilton matches his relaxed tenor saxophone to the exceptionally elastic Bill Charlap Trio on this first-class passage through ten standards. Though Scott made his name as a young turk who embraced swing style playing, this session proves (again) that he can play post-war jazz too, and the highlights are a pair of faster tunes by Dizzy and Bud Powell that force the band to play beyond its obvious comfort zone. These guys can play this stuff in their sleep, and that's the problem on the ballads -- they're gorgeous, and it you don't have a dozen tenor-plus-rhythm records already, these will suit you right up, but they're not distinguished by any excitement, innovation or drama. The faster tunes elevate everything, particularly when Charlap is soloing. He will always be compared to Bill Evans, but it's apt -- his playing bristles with invention and a rhythmic nimbleness that forces his Maserati band mates (Peter Washington on bass and Kenny Washington on drums) to up-shift. On "Blue 'n' Boogie" Charlap plays lines that dodge every clich� of jazz improvising (no easy blues runs or cheap quotes) and seem to be inventing a new language. It's a thrill and shows why this trio is considered one of the best in New York today. Hamilton, back in town after moving to London, seems to understand that the stakes are suddenly higher, and his burnished tone takes just a hint of Getz-ian urgency. It's a nice pairing, but there a few too many ballads that make you feel that you've heard it all before.
Will Layman
Madison, Dress Them One by One EP (Gables) Rating: 7
Twenty-four-year-old Madison is an indie artist who sounds like she should be on VH1. I mean this, surprisingly, as a compliment. Dress Them One by One is a rarity, a four song EP where each of the songs could be a potential single. On her first recording, Madison sounds like she's been huge for years, it's like she's arrived as a readymade pop star. Madison's mastery of the pop hooks are aided by her gritty, yet undeniably forceful, vocal styles, but she tempers the undeniable poppiness of her songs by adding just a hint of trendy post-punk edge. She has the stuff to breakout, but Madison may never get anywhere with her rather dark subject matter. The killer hook on the opening "Happy Days" is "I'm off the pills and my head's all clear" and the song "PPS" is an acronym for "Personal Porn Star". Still, Madison doesn't seem to want to become the next Patti Smith, she seems to be gunning to be the next Pat Benatar. Again, oddly enough, I also mean that as a compliment. If she can come up with an entire album filled with songs this good, there's no telling where her career could go.
Hunter Felt
The Curtains, Vehicles of Travel (Frenetic)
San Francisco's The Curtains have made a curious little record with Vehicles of Travel. The album contains 23 songs, which seems a bit overwhelming, but none of them is longer than two and a half minutes. In fact, only four reach the two-minute mark, as most of them come and go within 90 seconds. These aren't so much songs as mini-musical explorations, from guitarist Chris Cohen, keyboardist Greg Saunier (both members of Deerhoof) and drummer Andrew Maxwell (of Open City). Most songs feature some sort of noodly guitar riff from Cohen, which is then mimicked by Saunier, with Maxwell infusing some odd time signature. There is hardly anything resembling a verse, and certainly nothing resembling a chorus. It certainly keeps things from ever getting monotonous, and the trio takes what should be difficult listening and manages to make it both inviting and soothing. There aren't too many singularly memorable moments, but the album floats along quite enjoyably.
David Malitz
Crash Kelly, Penny Pills, (Liquor and Poker Music)
Remember Gilby Clarke, the erstwhile Guns 'n' Roses guitarist who released a handful of serviceable rock records back in the mid-'90s? Clarke may be off most folks' radars these days, but Sean Kelly, frontman and driving force behind Toronto, Canada, quartet Crash Kelly sure hasn't forgotten Clarke and his modus operandi. On Penny Pills, his band's debut, Kelly borrows liberally from the Clarke playbook: borrowing liberally from '70s rockers like T. Rex and Aerosmith, and '80s gritty/glammy types like RATT and, well, Guns 'n' Roses. It's all pretty standard cock rock, from the swaggering opener "She Gets Away" to the adrenaline buzz of "Easy and the Fifth". Kelly also shares Clarke's affinity for cover tunes; while Cheap Trick's "ELO Kiddies" works just fine, Kelly and co flub Rainbow's "Since You Been Gone", draining all the urgency from the song. By and large, though, Penny Pills is done well, and these days, with seemingly every guy with a guitar slung over his shoulder going ga-ga for New New Wave, it's fun to hear a band just plug in and kick ass. Instantly dated, but enjoyable.
Stephen Haag
Various Artists, Narnack Records Is... A Fist-First Sampler of New Music (Narnack) Rating: 5
Packed to the gills with seventy-minutes of music at half the cost of a regular CD, Narnack's sampler is a fine introduction for anyone looking to explore the roster of out-there talent the label has assembled. Mixing unreleased and previously available material, there is something among these 21 tracks that will catch the ear of any fan of adventurous music. For me, I was pleased to discover the gospel-noise-punk rave up of the Coachwhips, and "I Made a Bomb" -- from that band's Peanut Butter & Jelly Live at the Ginger Minge album -- is a great track. I had a lot of hope for the Tynodai Braxton track, as I have been reading much about him of late, but "October" disappoints with a nearly 10-minute running time that never seems to go anywhere. The roster's true surprise, among the glut of bands cranking their amps to 11, is Langhorne Slim. Falling somewhere between Dylan and Banhart, I will be eagerly anticipating his forthcoming longplayer. As with most compilations of this sort, you probably already know whether or not you're going to be picking this up, but if you're undecided, I urge you to at least check out the group's I've mentioned.
Kevin Jagernauth
Spike Priggen, Stars After Stars After Stars (Volare) Rating: 4
Why? What reason could Spike Priggen possibly give to convince me that, as an up and coming singer-songwriter, a covers album was the correct route to take with his second album? Stars After Stars After Stars is that album, and to his credit, Priggen manages to fit each and every song neatly into his pleasant, melodic power-pop template. Less fortunately, that template is a bit lacking in originality and excitement. Most of the songs sound as if Priggen is merely going through the motions, singing a song he knows for the sake of singing it, and then giving it a slick polish via the wizardry of modern production. Sometimes it works -- the sinister undertone of The Jacobites' "Big Store" is convincing, and Hot Bodies' "In the Inside", which opens the album, is pleasant enough to drive on a sunny day to. Still, The Ramones' "Questioningly" is sapped of all its sincerity, and Priggen just can't pull off the youthful vigor of Alice Cooper's "Eighteen". Priggen would be wise to stick to showing us more of himself before he tries something like this again -- there's just no personality to grab onto here, making Stars After Stars After Stars an ultimately too-taxing listen.
Mike Schiller
Later Days, Songs of the Watchmaker (Scarcelight) Rating: 4
Wayne Jackson likes computers. How else to explain this album of computer generated or machine oriented blips, bleeps, quarks and quirks. The album opens with "Evimx 15" which sounds like a kitchen that is about to explode thanks to Dr. Bunsen Honeydew and Beaker. Later on this style returns during "Evimx 6". It's a song/experiment that is difficult to explain unless heard (endured?). Think of a Lou Reed's Metal Machine Music if done by Eno and you might get the gist. Ditto for "Differentiation" although there is more of a rumbling undercurrent to this baby! Throughout there are moments of "music", especially on the haunting, worldly and eerie "Family Inharmonic". "Audiomata" is pushes the boundaries with whirling soundscapes, but generally this is an album that would fit well in a Star Wars film. That is if they were lacking the sound of an inter-galatic internet connection on dial-up.
Jason MacNeil
Scott Fisher, Scott Fisher (Tazmoe) Rating: 6
I suspect it's impossible to dislike Scott Fisher's eponymous debut, seeing how piano-based rock is enjoying a full-blown renaissance-albeit the sterile, workmanlike kind perfected by Five for Fighting and Keane. Fisher's brand is far more energetic and soulful than that, and by virtue of its clever use of Wurlitzers and Fender Rhodes, much more interesting. Fisher is no doubt a talented keyboardist, but he sometimes falls into the trap of making sure we all know it (to worst effect on the ponderous "Interlude"). He's at his best when he allows his piano to complement his songwriting and not the other way around, showcased brilliantly on "Nothing" and the Spoon-like "Chemicals". The obvious comparison here is to Ben Folds (the ska-jazz of "Struggle" echoes Folds' "Battle of Who Could Care Less"), but I reckon if the guys from Train relied more on the piano, they'd sound a lot like this. Make of that what you will, but a guy with Fisher's chops should aim for more ambitious comparisons on future releases.
Michael Pucci
Mt. Gigantic, Old Smiler (Friends and Relatives) Rating: 4
This group from Bloomington, Indiana would bring to mind a young and spry Violent Femmes judging by the odd singing and bizarre effects used at times during "Bring Back The Healthy". Singer Wayne Sebastian mixes a rampant indie rock with various changes in tempo and mood over its six minutes. "Dip Into My Daddy" follows a similar blueprint but features more of singer Megan Downey before over-dosing temporarily on the hi-hat. The group could be mistaken for the Polyphonic Spree if they practiced in a very cramped garage. "Granpa Plays The Drums" is another tune that you would have to listen to at least three or four times to appreciate, with the distant Neil Young-ish vocals complemented by a military drumbeat. A complete waste of time though is "Raechel And Her Children" which is a cross between At The Drive-In and Controller.Controller. "Bells" is another difficult song to get into with the band resembling a poor man's Devendra Banhart. This is only an extremely select few's cup of tea.
Jason MacNeil
Folk?, Folk? (Vibrating Needle) Rating: 5
Bill Fletcher and Mike Detmer have set an admirable goal for themselves with their Folk? project, by asking themselves and listeners to consider what the definition of "folk music" really is. The common perception falls somewhere between the dust bowl realism of Woody Guthrie and the polished harmonizing of the '60's revivalists. But folk according to Folk? seems to fit the broader description of "music of the people." And these people from southern Indiana have crafted a record that is filled with electronic beeps and blips and traditional pop constructions instead of whiskey, sawdust and mandolins. "Nintendo Pop", "Love at Point Blank", and "Float Away" fall in line with many of Folk?'s forebears from the same general region: GBV, Swearing at Motorists, Pere Ubu. About half the songs stick, catchy and strong enough that they could exist without the quirky gadgetry just fine. The rest gets repetitive and old real quick.
Michael Metivier
The Distortions, Exploding Teenage Body Part (Blank) Rating: 8
Teeming with the sort of tight and infectious pop rock that has saturated the airwaves a la Interpol and The Killers, this L.A. trio hit the ground running with the pleasing ear-candy title track full of short, choppy guitar riffs. Lead singer "F" also shines throughout, especially on the garage-like Westerbergian power pop of "Getting What We Deserve". "I'm no better than the East Coast small town hell you see," he sings before turning into verse two. The strength of the album is the consistency of the songs, although a tad low-key is the mid-tempo "Books" that name drops Pulp's Jarvis Cocker among several others. Nonetheless they mine this format brilliantly on the aptly named "Shoegazer". Just as stellar is the slow-building "Hinterland" that sounds like The Cure singing "Crimson And Clover". The greatest of the lot though is the shimmering and airtight Mats-ish "The Dogs" that is pure 4/4 rock glory. A close second however is the feathery, almost dreamy "Mansion". It's a well-crafted, well-rounded nine songs. The only problem is you'll have to wait for more!
Jason MacNeil


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Khoomei (Overtone singing, also known as overtone chanting, or harmonic singing) is a magical art of singing created by Mongolians: The singer can create two pitches at the same time, simply using his vocal organ. The basic structure of the relationship between pitches in Khoomei is a frequent low-pitch together with the melody flowing. Khoomei can be divided into "overtone Khoomii", "tremolo Khoomei" and "compound Khoomei". It is unparalleled among all Chinese folk songs. Khoomei is practiced today among Mongolian communities in several countries, especially in Inner Mongolia in northern China, western Mongolia and the Tuva Republic of Russia. On Sep 30th 2009, Khoomei was inscribed on the Representative List of the Intangible Cultural Heritage of Humanity by the UNESCO.
History of Khoomei
According to the records, the history of Khoomei dates from Hun's time. The art of Khoomei was created by the time Mongolian nation formed at the latest. The ancestors living in the Mongolian plateau imitated the sound from the nature piously when they were hunting and herding. They believed that it was an important way to communicate and get along harmoniously with the nature and the universe. Thus, some substantial of the human vocal organs was developed, allowing one person to create "harmony" when he was imitating the sound of waterfalls, mountains, forests and animals, which was the embryo of Khoomei. There is not abundant repertoire of Khoomei, limited by its specific singing techniques. The first basic category is the singing of the beauty of nature. The second one is the conveying and mimicking the lovely images of wild animals, such as Cuckoo which retains the music played during the hunting age. The third category is the praising of fine horses and grasslands.
The main musical style of Khoomei is short-tune songs; however, a few brief long-tune songs are available. Judging from the story about its origin and the subject matter of repertoire, the throat-singing is believed to be an outcome of the hunting culture of the Mongolians.
Artistic Feature
The singing of Khoomei is developed under special regional, productive and living circumstances. Its way of giving off sound and feature of voice is uncommon, which is different from the famous Mongolian long tone singing. Experts in vocal music describe the singing of Khoomei as "as high as the sky; as low as the bottom of the ocean; as wide as the whole world." The principle of the way of giving off sound in Khoomei is special. The vocal cord sometimes vibrates and sometimes does not, making an echo using the breath from inside the cavity. With special vocal technique, one person can create two pitches at the same time. The singer stops breathing and lets the breath strike the vocal cord fiercely, and then the bubble sound is created, forming the low-pitched voice part. On this basis, the singer controls the echoes of his mouth ingeniously, emphasizing and centralizing the overtone to create a clear high-pitched voice part with mental sound, gaining a wonderful vocal effect.
As a special form of folk singing, Khoomei is the splendid creation of Mongolian nation. It displays Mongolian's deep philosophical thoughts and feeling toward the universe and everything, expressing Mongolian 's pursuit of the concept of living and developing harmoniously, as well as a healthy and optimistic appreciation.
Heritage and Present Situation
Khoomei is one of the oldest art forms of Mongolian nation, remaining more factors of ancient singing. It is an echo from the nation's deep memory. Khoomei is closely related to Mongolian history and culture, contributing a lot to anthropology, ethnicity and folklore. Thus, inheriting and popularizing the art of Khoomei does not only make a hit to international music, but also draws much attention from experts in folk music and vocal music. Lv Yi, the honorary chairman of Chinese Musicians Association said: "The Mongolian people can sing a kind of song in which one person can create two pitches at the same time. This is unimaginable to us and we should study on it seriously." Khoomei is the oldest musical heritage with highest antique value. Being a living fossil, it is one of the musical heritages with highest scientific and acknowledge value among all the heritages of all kinds of human races and nations ever discovered.
Khoomei has been lost on the Inner Mongolia Grassland for more than 100 years. It has bordered on the exyincyion even among the Mongolian people living in Alta region (in Xinjiang). Thus, reviving and exploring this cultural heritage which used to belong to the Chinese nation is an emergency with immeasurable practical significance and profound historical influence. Salvaging and protecting the magical singing art of Khoomei is important and urgent.


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Cheek Filler or Mid Face Lift?
I am 31 years old. I have extremely hollow flat cheeks, hollow eyes, and now pre jowls and lots of new lines forming and dents on chin. My skin is... READ MORE
What is a Mid-face Lift?
What is a midface lift? How is that different from a regular facelift or a mini face-lift? READ MORE
Permanent Solution for Marionette Lines, Drooping Cheeks and Jawline?
I'm 35 and am interested in addressing my mid/lower cheek and jawline/mouth areas for droopiness. I've had a downturned mouth with slight marionette... READ MORE
Best Options for Jowl Reduction for a 32 Yr Old Female
I have a slight double chin and obvious jowls. The jowl on my left is visibly larger than on my right. Oddly, I'm quite thin and have been so all... READ MORE
What Does a Cheek Lift Cost?
Is a cheek lift, or mid-face lift less expensive than a full face lift? What is the average price of a cheek lift? READ MORE
What Are the Different Cheek Lift Procedures?
I'm a 35 year old female and due to early aging because of hereditary traits. I'm interested in a Cheek lift procedure. It seems from what I've read... READ MORE
I'm 23 Years Old and my Face Sags. Would a Mid-Facelift Help?
I'm 23 years old and my face sags especially around the mouth. I'm not over weight, I stay out of the sun and live a healthy life style so... READ MORE
Cheek Lift for Thinner Face and Defined Cheekbones?
I'm 20 years old and I want a cheek lift, my lower face is too round but I really like the way my face looks when I pull the skin on the side of my... READ MORE
Lifting Corners of the Mouth by Mid-face Lift?
How much will a Mid-face lift raise the corners of the mouth? I would like to avoid the scars of a corner of the mouth lift. And I have sunken cheeks.... READ MORE
Fleshy Saggy Cheeks At Age 30? (photo)
I just turned 30 this year, but my fleshy cheeks are sagging causing the Nasolabial fold. My doctor advised permanent filler, but i am concern about... READ MORE
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I've noticed my left cheek is less firmer than the right cheek a couple months ago, I tried doing face exercises but I guess it made the issue... READ MORE
Cheek Lift and Other Options for Patients in Their 20s
I am 23. I have droopy cheeks, extra skin/fat in the jowl/chin area, and visible lower eye whites. When I smile these issues are accentuated. Would a... READ MORE
Can Cheek Lift Help with Hollow Eyes?
Hello. I am 30 years old female from Turkey. My main problem is hollow eyes and sagging cheeks. Some of the Drs. advised Endoscopic Mid Face... READ MORE
Cheek Lift at 20 Years Old to Correct Nasolabial Folds/smiles Lines?
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Cheek Lift Procedure and Finding Experienced Surgeon?
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What is the Difference Between High Cheekbones and Prominent Cheekbones?
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How Can I Tighten the Skin on my Cheeks?
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The library has many different collections available, all based on the curriculum taught at NDSCS. There are also leisure materials in the form of CDs, DVDs, Book Club fiction, graphic novels and a variety of general interest materials.
The library subscribes to all North Dakota daily newspapers, as well as some from bordering states. Some weekly papers are sent without charge by their publishers.
Library material in the public area may be used inside the library by anyone. These items and any material kept in closed stacks and behind the Circulation Desk may be checked out only with a valid library card.


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I sent this directly to Harsha by mistake: Hi 2009/7/8 Harsha Hegde <harsha(dot)hegde(at)vonage(dot)com>: > > Hello Friends, > > I have installed postgres client on an Ubuntu machine. However, when I > try to run 'psql', I get this error message: > > # psql > /usr/lib/postgresql/8.3/bin/psql: symbol lookup error: > /usr/local/lib/libreadline.so.5: undefined symbol: PC Google returns many results for the error "/usr/local/lib/libreadline.so.5: undefined symbol: PC". It is not clear to me why so many people encounter this error, though. By the way, why do you have a libreadline.so.5 in /usr/local/lib? Official Ubuntu packages are never installed to /usr/local. I think the problem is that psql is finding the wrong libreadline. What does this give you: ldd /usr/lib/postgresql/8.3/bin/psql In order to get psql to use the correct libreadline, you have several options. 1.) Remove the one from /usr/local/lib and then run "ldconfig", but this might break other things. Since it should not have been installed there by official Ubuntu packages, I hope you know what it is that needs it and can decide if this is a problem. If you try this, first rename it to something else and see what breaks. Then you can rename it back again if necessary. 2.) Configure ld.so.conf (or ld.so.conf.d/*) to ignore /usr/local/lib (i.e. comment it out. It should be in /etc/ld.so.conf.d/libc). Then run "ldconfig". This is similar to option 1. i.e. it could break other things, but should not break any official Ubuntu packages. 3.) Configure ld.so (same files as for option 2) so that /lib and /usr/lib are before /usr/local/lib when you run "ldconfig -v". Not sure about this, but you might just be able to put them above /usr/local/lib in /etc/ld.so.conf.d/libc. This should be safe, but keep a live CD handy in case. Remember to run "ldconfig" after changing the files. 4.) Use LD_PRELOAD to force psql to use the correct libreadline. This is the ugliest solution and you would have to do it every time you run psql (or write a script that does this), so I don't recommend it: LD_PRELOAD=/lib/libreadline.so.5 psql also, I haven't tested it. It won't break anything and I'm pretty sure it will work, but as I said, it's ugly. The best solution, I think, is number 1, but only if you don't actually need the version in /usr/local for some reason. I hope this helps and is not too confusing :) -- Michael Wood <esiotrot(at)gmail(dot)com>
Next: From: Michael Gould Date: 2009-07-09 15:23:02 Subject: Setting up security for development Previous: From: Michael Wood Date: 2009-07-09 15:18:21 Subject: Re: psql undefined symbol error on Ubuntu


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NEW YORK (TheStreet) -- Back in 2011, when Steve Jobs was very ill, there were persistent questions about Apple's (AAPL) CEO succession plan. The most bizarre names were put forth by journalists, including those who had no experience as a corporate executive officer. But the only real candidate all along was Tim Cook, a man Mr. Jobs had great confidence in.
Now that Mr. Cook, who is 53 years old, is the CEO, the worries about Apple leadership are over -- for the time being.
However, corporate succession plans must still be written. Heaven forbid that Mr. Cook, in good health, should become seriously ill or get hit by a bus. So there should be, and certainly is, a new plan.
My candidate is Phil Schiller who is also 53. Over the years, as Senior Vice President of Worldwide Marketing, no one has drunk more deeply from the well of Apple Kool-Aid than Mr. Schiller. Jonathan Ive isn't really an option because he's a designer, never been trained as a CEO, and is far more valuable right where he is.
A Trek in the Wilderness
In terms of long-term planning, many thought that Scott Forstall would someday, when he grew up, become the next generation Apple CEO. Unfortunately, Mr. Forstall may have thought that because he was the protege of Mr. Jobs that his future was secure at Apple. What stymied that was his youth and inability to work as a team member towards a larger cause, and that got him on the wrong side of Tim Cook, Bob Mansfield and others.
Perhaps the trek of Mr. Forstall in the wilderness, just as Mr. Jobs experienced after he was forced out of Apple in 1985, will bring Mr. Forstall full circle. Regrettably, history seldom repeats itself in that fashion.
At some point, Apple's executive team will need to think about what Apple's leadership will look like in a few years. It's not that I expect anyone on this team to be soon incapable of carrying out their duties anytime soon. Rather, it's a question of how Apple's leadership responds to the the natural course of aging, competitive challenges and the changing demographics of customers in the U.S. and worldwide.


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New, New York Harbor Current Meter
NOAA uses data from a new current meter in New York harbor operated by New Jersey's Stevens Institute of Technology.
The system provides enhanced real-time information to mariners travelling through the nation's second busiest port.
The Stevens current meter measures the direction, speed, and volume of ocean currents in the harbor's navigation channels, north of the Narrows between Brooklyn and Staten Island. Its data will be used in NOAA's Physical Oceanographic Real-Time System (PORTS®) system, which delivers real-time environmental observations, forecasts and other geospatial information to mariners in 21 major U.S. harbors. The system makes maritime commerce more safe and efficient by giving ship captains instant measurements of the water levels and temperatures, and the direction and speed of the current and wind as they come in and out of port.
Stevens is a partner in the NOAA-led U.S. Integrated Ocean Observing System (IOOS®) , and is the first academic institution that is part of IOOS to have its research data incorporated into the NOAA real-time PORTS program.
"This new sensor will provide crucial current information halfway between the Verrazano Narrows Bridge and Manhattan, the primary navigation route into New York and New Jersey ports. It's a great addition to PORTS," said Richard Edwing, director of NOAA's Center for Operational Oceanographic Products and Services . "This collaboration between Stevens and NOAA gives us access to previously untapped data to help us address marine commerce and other coastal issues. It also lays the groundwork for future federal-regional collaborations."
By providing real-time tide, current, and other information, NOAA's PORTS program helps reduce the chances for accidents. Also, enhanced marine information can increase the amount of cargo moved through a port and harbor by enabling mariners to safely use every inch of dredged channel depth.


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ISRN Oncology
Volume 2012 (2012), Article ID 956190, 6 pages
Ovarian Reserve in Women Treated for Acute Lymphocytic Leukemia or Acute Myeloid Leukemia with Chemotherapy, but Not Stem Cell Transplantation
1Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
2University Hospitals, Case Western Reserve University, Suite 310, 1000 Auburn Drive, Beachwood, OH 44122, USA
3Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
4Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
5Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Received 12 June 2012; Accepted 15 August 2012
Academic Editors: G. Gatti and L. Hunakova
Copyright © 2012 Brooke V. Rossi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose. It is well known that chemotherapy regimens may have a negative effect on ovarian reserve, leading to amenorrhea or premature ovarian failure. There are little data regarding the effects of leukemia chemotherapy on ovarian reserve, specifically in women who received the chemotherapy as adults and are having regular menstrual periods. Our primary objective was to determine if premenopausal women with a history of chemotherapy for leukemia, without subsequent stem cell transplantation, have decreased ovarian reserve. Materials and Methods. We measured ovarian reserve in five women who had been treated for acute lymphocytic leukemia (ALL) or acute myeloid leukemia (AML) and compared them to age-matched control women without a history of chemotherapy. Results. There appeared to be a trend towards lower antimullerian hormone and antral follicle counts and higher follicle-stimulating hormone levels in the leukemia group. Conclusion. Our results indicate that chemotherapy for AML or ALL without stem cell transplantation may compromise ovarian reserve. Although our results should be confirmed by a larger study, oncologists, infertility specialists, and patients should be aware of the potential risks to ovarian function and should be counseled on options for fertility preservation.
1. Introduction
Approximately 20,000 reproductive-aged American women carry a diagnosis of leukemia [1]. For women less than 45 years old at the time of diagnosis, the 5-year survival rate is approximately 50% and 40% for women with AML and ALL. Cancer patients are not only focused on survival, but on quality of life and long-term plans, such as family building. Health care providers have recognized the importance of fertility to cancer patients and the impact of cancer treatment on fertility. The American Society of Clinical Oncology recommends that fertility preservation be discussed at the time of diagnosis [2, 3].
Chemotherapeutics have a range of gonadotoxic effects. In general, methotrexate, fluorouracil, vincristine, bleomycin, and dactinomycin are associated with a low or no risk of amenorrhea, which is used as a surrogate marker for infertility, while alkylating agents are more likely to cause ovarian damage and amenorrhea [2]. Alkylating agents, like cyclophosphamide, may lead to early menopause by damaging primordial follicles [4, 5]. Anthracyclines, used for induction remission and postremission chemotherapy in young adults with acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL), also likely lead to ovarian damage [6, 7].
Ovarian reserve refers to the number of primordial ovarian follicles in the ovaries and is related to fertility potential [8]. Infertility is more likely in women with reduced ovarian reserve [9]. Ovarian function can be monitored clinically, by the presence of regular menstrual periods. However, a menstrual cycle is not synonymous with normal fertility or ovarian reserve. In fact, women who cycle regularly may have diminished ovarian reserve [10]. Thus, biochemical tests are often employed to assess ovarian reserve. Ovarian reserve can be measured by menstrual cycle day 3 follicle stimulating hormone (FSH) and estradiol, inhibin B (INB), ovarian antral follicle count (AFC), or antimullerian hormone (AMH).
In the current study, we examined ovarian reserve in women in first complete remission of leukemia who underwent treatment with standard chemotherapy, but who did not require stem cell transplantation. We hypothesized that premenopausal women with a history of chemotherapy for leukemia, even if stem cell transplantation is not performed and menstrual cycles are regular, have decreased ovarian reserve.
2. Materials and Methods
We conducted a cross-sectional study of premenopausal women, aged 18–45, with a history of chemotherapy treatment for ALL, AML, or acute promyelocytic leukemia (APML). The Institutional Review Board of Dana Farber/Harvard Cancer Center approved this study. All participants signed informed consent and were compensated for participation.
There was a minimum of at least 6 months since the completion of chemotherapy. Participants could be in remission or on maintenance therapy. A healthy aged-matched comparison group from the same catchment area was recruited. Women with infertility and those with medical conditions that may compromise fertility or affect ovarian reserve markers such as a history of hysterectomy or oophorectomy were excluded. Women using hormonal therapy were excluded or required to stop it for one month prior to study participation.
Tests for ovarian reserve included serum AMH, estradiol, FSH, INB, AFC and ovarian volume. All participants were tested once on cycle days 2–4 of their menstrual cycle. The primary author performed all transvaginal ultrasounds to calculate AFC, and ovarian volumes. The AFC included all follicles in both ovaries 2–10 mm in diameter. Ovarian volume was calculated by multiplying the longest dimension of the ovary (in cm) by the two orthogonal dimensions by a factor of 0.523: ovarian volume = length × width × thickness × 0.523 [11].
We stored serum samples at −70°C. All samples were batched and concurrently analyzed. Serum estradiol was measured by the Access chemiluminescence immunoassay (Bechman Coulter, Fullerton, CA); coefficient of variation (CV) was between 21–50% for levels of estradiol 120–50 pg/mL. Serum FSH was measured by the Access chemiluminescence immunoassay (Bechman Coulter, Fullerton, CA), CV < 10%. Serum AMH was measured by enzyme-linked immunosorbent assay (ELISA) (DSL Laboratories, Fremont, CA), intra-assay CV <5% and interassay CV 6%. Serum INB was measured by ELISA (DSL Labs, Fremont, CA), intra-assay CV <5% and interassay CV 7%.
The power calculation was based on a 2-sample independent -test to compare the mean AMH level between the leukemia group and the comparison group. In a previous study, the response within each subject group was normally distributed with standard deviation 0.9 ng/mL [10, 12]. If the true difference in the cancer participants and comparison means is 1.0 ng/mL, we needed to study 14 women with leukemia and 14 comparison women to be able to reject the null hypothesis that the population means of the cancer and comparison groups are equal with probability (power) 0.8. Assuming 20% loss to followup, we tried to recruit 17 leukemia patients and 17 comparison participants. However, we were only able to recruit 5 participants. Since the relapse rates are high and overall survival without a transplant is low in AML and ALL, there were a limited number of eligible patients. Our participants were aged matched (1 year) to ensure equal age distribution in both groups. We matched the comparison participants to the leukemia participants 1 : 1.
We compared the continuous variables (AMH, estradiol, FSH, AFC, INB, and ovarian volume) between the leukemia subjects and the comparison subjects using Wilcoxon signed-rank tests for matched pairs. In addition, we used McNemar's test based on the exact binomial distribution to look at the rate of decreased ovarian reserve markers within each group. We defined decreased ovarian reserve as menstrual cycle day 3 FSH of ≥10.0 mIU/mL, estradiol of ≥80 pg/mL, INB of <25 pg/mL, AMH <0.9 ng/mL, or AFC of <5. The type I error probability for all two-sided statistical tests was 0.05. Analyses were performed using Statistical Analysis Software (SAS) version 9.1 (SAS Institute, Inc., Cary, NC).
3. Results
Five women with leukemia and five comparison women participated. At the time of study involvement, all of the participants had completed therapy; none were on maintenance therapy. Table 1 represents their treatment history and Table 2 describes menstrual change in regards to chemotherapy. None of the participants had a history of pregnancy prior to or after chemotherapy; however, none had attempted conception. The average age of menarche was 11.6 ± 0.6 years. Sixty percent of participants used only GnRH agonist menstrual suppression during chemotherapy and the other 2 participants used combined oral contraceptive pills (COC) and a GnRH agonist. The mean duration of GnRH agonist therapy was 16 months (range 3–31 months).
Table 3 includes markers of ovarian reserve. There were no significant differences in any of the markers of ovarian reserve between the leukemia and the comparison group. However, there was a trend toward a lower AMH and AFC and higher FSH in the leukemia group. Three of the women in the leukemia group had abnormal AMH and FSH levels, compared to one in the comparison group. The 3 women with subnormal AMH levels had duration of treatment >12 months and one of these women was 35 years old at the time of treatment.
4. Discussion
In this age-matched study of ovarian reserve in premenopausal women who underwent chemotherapy without transplantation for acute leukemia, there were no statistically significant differences in ovarian reserve markers between the groups. However, there appeared to be a trend towards decreased ovarian reserve in leukemia survivors. Survivors may be falsely reassured that their regular menses represents normal ovarian reserve and may not seek consultation for fertility preservation until near ovarian failure. Our findings suggest that patients treated with chemotherapy for leukemia who continue to menstruate should be tested for decreased ovarian reserve after treatment. Furthermore, they should not delay consultation with an infertility specialist if they have difficulty conceiving.
In the oncology literature, "ovarian failure" is described in a number of ways: treatment-induced amenorrhea, menopausal levels of FSH or estradiol, menopausal symptoms, or infertility. In our study, women with longer treatment durations had lower ovarian reserve. Similarly influenced by their age at treatment and the stage of cancer, approximately 50–80 percent of women that received chemotherapy for Hodgkin's lymphoma had secondary amenorrhea [13, 14]. However, 75 percent of women with a history of treatment for Hodgkin's lymphoma achieved pregnancy without assisted reproductive technologies [15]. Of note, the mean age of diagnosis was 23 years old, and those treated after the age of 30 were less likely to achieve posttreatment pregnancy. Aisner et al. found a similar pregnancy rate in their female Hodgkin's survivors, and as the length of time after therapy increased so did the probability of pregnancy [16]. Unfortunately, similar data in leukemia survivors do not currently exist outside this paper. Given the overwhelming evidence of diminished ovarian function following treatment for other hematologic malignancies, a reproductive-aged woman with a new hematologic cancer diagnosis should be aware of her potential options to retain her fertility and ovarian function [17]. Such options include oocyte, ovarian tissue, or embryo cryopreservation, which are selected based on the patient's clinical and social situation.
There are limited data on pregnancy outcomes and infertility incidence after cancer treatment. However, there are a small number of epidemiologic studies examining parenthood after a history of cancer treatment. Compared to the Norwegian general population of women, of whom 79% become parents, significantly fewer women (66%) with a history of cancer become parents. Moreover, the pregnancies of women with a history of cancer were complicated by low birth weight and premature deliveries [18]. Of note, 31% of these women had malignant melanoma (none specified as having leukemia). These findings are similar to a Finnish study that measured probability of parenthood in women diagnosed with cancer between 20–34 years old compared to their siblings [19]. The probability of parenthood in survivors compared to siblings was 38% versus 73%. Only a small proportion (3.6%) of those studied had leukemia.
There are more data on pregnancy outcomes of women diagnosed with leukemia as children than women diagnosed as adults, which reflects the improved survival rate in this age group compared to adults with acute leukemia. Among participants in the Childhood Cancer Survivor Study, the chance of live birth was significantly less (RR 0.52, 95% CI 0.36–0.76) for women treated with chemotherapy compared to their healthy siblings [20]. For women who did deliver, offspring were more likely to be of low birth weight. Signorello et al. also found that survivors were nearly twice as likely to have premature deliveries [21]. The aforementioned studies describe pregnancy outcomes and parenthood for many types of cancer, but leukemia patients are not well represented. Leukemia survivors are a large part of the Childhood Cancer Survivor Study participants, but these females were diagnosed when younger than age 22. Thus, the oncology and fertility literature lacks information on ovarian reserve after adult diagnosis and treatment of leukemia.
Another aim of our study was to determine which ovarian reserve markers performed best in this population. The optimal ovarian reserve testing may be different for cancer survivors than for women with other infertility etiologies. In a study of Childhood Cancer Survivors, women with normal FSH levels (<10 mUI/mL) and normal menstrual cycles were found to have a lower AFC and ovarian volumes compared to age-matched controls [22]. Similarly, AMH levels were lower in women treated as children with chemotherapy for Hodgkin's lymphoma, even in women with normal FSH and INB levels. Thus, AMH appears to be an earlier and more sensitive marker of ovarian reserve in women with a history of chemotherapy [10]. Our study also showed a trend towards low AMH and AFC, with normal FSH in the leukemia group.
Unlike FSH or estradiol, the interpretation of AMH is not menstrual cycle-day dependent [23]. During and after treatment, she may be amenorrheic from the chemotherapy or GnRH agonist use, and her cycle day unknown. Also, she often cannot postpone urgent chemotherapy for a menstrual cycle day 3 FSH evaluation. Thus, the ability to evaluate ovarian reserve regardless of menstrual status suggests that AMH is an excellent ovarian reserve marker for the cancer population.
Current options for fertility preservation in cancer patients receiving chemotherapy include embryo cryopreservation after in vitro fertilization (IVF), oocyte cryopreservation, and ovarian suppression with gonadotropin releasing hormone (GnRH) agonists or antagonists [2]. In addition, ovarian tissue cryopreservation, currently experimental, may be considered more in the future [24]. Aside from IVF potentially being cost or time prohibitive for young women, especially those needing urgent chemotherapy for acute leukemia, IVF and embryo cryopreservation may not be desirable to single women, as they would need donor sperm. They may consider oocyte cryopreservation; however, this is still thought to be experimental, requires ovarian stimulation, and may not be feasible in the acute leukemia population because of the need to delay chemotherapy [25]. Many providers offer women GnRH agonists, as it may be covered by insurance and can be given without delaying chemotherapy. However, in 2006, the American Society of Clinical Oncology stated there was "insufficient evidence regarding the safety and effectiveness of GnRH analogs and other means of ovarian suppression on female fertility preservation [2]."
The primary limitation of this study was its size and we encourage providers to consider this when interpreting the results. Although our participants were from an academic center in a large city, we still had difficulty with recruitment. A multicenter study is required to achieve recruitment for an adequately powered study. Low numbers of eligible patients may reflect that very few women with leukemia are able to be cured with chemotherapy alone. For those who have a good prognosis, and may not need transplantation, our study suggests that there may be long-term implications regarding fertility. Due to the lack of data in the field regarding the impact of leukemia treatment on menstrual cycles and infertility, we feel that our study is a worthwhile contribution and may assist with patient counseling. We believe that women treated with chemotherapy for leukemia should be counseled that their ovarian reserve may be negatively impacted.
In conclusion, we determined that premenopausal women who have received chemotherapy as adults for leukemia may have compromised ovarian reserve, even in the setting of regular menses. Oncologists, infertility specialists, and patients should consider our results when discussing the impact of chemotherapy and fertility preservation. Further, women and providers may be able to have a more realistic conversation about the options for fertility preservation.
This project was supported by the Brigham and Women's Hospital Department of Obstetrics, Gynecology, and Reproductive Biology departmental funds. All authors declare that no competing financial interests exist.
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text:
STUDENTS from Coleg Gwent have won places at the UK finals of a hair and beauty competition after winning six silver and two bronze medals at the regional Welsh heats.
Hair and beauty students from both City of Newport and Cross Keys campuses took part in the Association of Hairdressers and Therapist competition taking part in timed styling for hair, makeup, body painting and nails.
Charlotte Ballinger, theatrical make-up student, 19, achieved silver in the bodypainting category for her look inspired by women's power suits.
Other winners included Lauren Thomas, of Llanwern High School, and Sophie Bartlett, of St Julian's School, who took silver and bronze in the ladies' evening-style hairup schools category.
Louis Jones, 26, hairdressing student, won silver for the bridal hair team, while Dominique Willis, 19, beauty therapy student, won silver in the bridal make-up team event.
Jessica Williams, 18, and Alicia Thorne were awarded silver and bronze medals for their classic 1960s make-up looks, and Viktorija Skinkyte, 22, beauty student, achieved silver in the nails category.
The finals of the AHT competition will be held in Blackpool on March 18.


text:
Framing Authority:
Writers in sixteenth-century England often kept commonplace books in which to jot down notable fragments encountered during reading or conversation, but few critics have fully appreciated the formative influence this activity had on humanism. Focusing on the discursive practices of "gathering" textual fragments and "framing" or forming, arranging, and assimilating them, Mary Crane shows how keeping commonplace books made up the English humanists' central transaction with antiquity and provided an influential model for authorial practice and authoritative self-fashioning. She thereby revises our perceptions of English humanism, revealing its emphasis on sayings, collectivism, shared resources, anonymous inscription, and balance of power--in contrast to an aristocratic mode of thought, which championed individualism, imperialism, and strong assertion of authorial voice.
Crane first explores the theory of gathering and framing as articulated in influential sixteenth-century logic and rhetoric texts and in the pedagogical theory with which they were linked in the humanist project. She then investigates the practice of humanist discourse through a series of texts that exemplify the notebook method of composition. These texts include school curricula, political and economic treatises (such as More's Utopia), contemporary biography, and collections of epigrams and poetic miscellanies.
Originally published in 1993.
The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Another Princeton book authored or coauthored by Mary Thomas Crane:
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text:
Beast Man red Spiked arm Band X1
Beast Man Whip
Mer Man Chest Armor
Man At Arms Arm Armor
Mosquitor Gun
Extendar shield
Faker Sword
Jitsu Sword
Type: Posts; User: tommyboy1972
Beast Man red Spiked arm Band X1
Beast Man Whip
Mer Man Chest Armor
Man At Arms Arm Armor
Mosquitor Gun
Extendar shield
Faker Sword
Jitsu Sword
Man At Arms Arm Armor
Man At Arms Leg Armor
Man At Arms Mace
Mosquitor Gun
Faker Sword
He-Man Sword
Trap Jaw claw
Trap Jaw Hook
Blade Sword
Dragstor Ripcord
Modulok guns (both) *Low Priority*
Modulok Tail *Low Priority*
Mosquitor Gun
Multibot waist piece (not middle one)
Blade Sword
Dragstor Ripcord
Evil-Lyn Wand
Hordak cape
Hordak Shield
Jitsu Sword
Blade Sword
Dragstor Ripcord
Evil-Lyn Wand
Hordak cape
Hordak Shield
Jitsu Sword
He-Man was not really big in my area when I was a kid. In fact I didn't really care for them much based off of the commercial - UNTIL my friend brought over his Castle Grayskull, He-Man, Skeletor and...
I'd be MUCH more interested in a 200X sub than a POP sub. I'd want -
Captain Miro
Tuvar/Baddhra 2 pack
Picked up one of my items.
Dragstor Ripcord
Evil-Lyn Wand
Hordak Shield
Hordak Cape
Jitsu Sword
Man at Arms Mace
UPDATED Thread
Bump with updates
Also have MOC Clawful
I'm trying to obtain some Vintage MOTU items -
Buzz Off Head...
Beastman Chest Armor (Red)
Beastman Arm Band (L&R - Red)
Dragstor Ripcord
Fisto Sword
Jitsu Sword
Leech Crossbow
Mantenna Crossbow
Selling a lot that has some nice vintage Pretenders in it -
Have a couple of ebay listings going on right now -
King Randor - http://www.ebay.com/itm/190778656792?ssPageName=STRK:MESELX:IT&_trksid=p3984.m1555.l2649
Lot 4 Meteorb group -...
Roboto - http://www.ebay.com/itm/Masters-of-the-Universe-200X-MOTU-Roboto-MOC-He-Man-Lot-/190753546327?pt=US_Action_Figures&hash=item2c69cc2057
Teela -...
DC Universe
Prices do not include shipping
$5 figures
DCSH Mongul
DCUC Riddler (Series 5) (w/cane)
Movie Masters Scarecrow
DCUC Mercury (scissors)
DCUC Creeper
Have a number of 200X I'm looking to trade or sell. If intersted in purchasing, please make an offer. I will only do trades/transactions within the US. Here is what I have (all are still in package)...
UPDATED first post
Still looking to do some trades... Everything still available above...
Added some more HAVES
MOTUC Faker MOSC
MOTUC Hordak MOSC
MOTUC Zodac MOSC
MOTUC King Randor MOSC
MOTUC Goddess MOSC
MOTUC Scareglow MOSC
MOTUC Man at Arms loose is fine
MOTUC Webstor loose is fine
Selling Trapjaw (reissue) and Count Marzo for $44 combined plus shipping. Both are MOC and include white mailer. Please PM to inquire. US and Canada only.
Lowered price. Need to move these out...
Entire lot is pending... Thanks
Only shipping within the US - Sorry international folks... :(
MOTUC Faker MOSC $25
MOTUC Man at Arms MOSC $25 (reissue version)
MOTUC Hordak MOSC $25
MOTUC Scareglow MOSC $25
MOTUC King Randor...
Updated items...
I have the following items available for trade or sale -
MOTUC Merman MOSC
MOTU Staction Grizzlor MOSC (cardback is not in great condition)
MOTU Staction Hordak MOSC (cardback is not in great...
Faker is no longer available. Thanks for all of the requests.
I have an extra MOC MOTUC Faker for sale. $32 plus shipping. I'd also be willing to trade towards a MOC MOTUC Beastman or MOC MOTUC He-Man. Feel free to contact me if interested. Ship within US only.
Looking to obtain some of the new MOTU Classics -
Heman MISB
Skeletor MISB
Beastman MISB
Stratos MISB
I do have a MIB King Greyskull available for trade. I also have lots of other stuff in...


text: Hello, The HList paper gives a type cast: class TypeCast a b | a -> b, b->a where typeCast :: a -> b class TypeCast' t a b | t a -> b, t b -> a where typeCast' :: t->a->b class TypeCast'' t a b | t a -> b, t b -> a where typeCast'' :: t->a->b instance TypeCast' () a b => TypeCast a b where typeCast x = typeCast' () x instance TypeCast'' t a b => TypeCast' t a b where typeCast' = typeCast'' instance TypeCast'' () a a where typeCast'' _ x = x and a type equality check: class TypeEq x y b | x y -> b instance TypeEq x x HTrue instance TypeCast HFalse b => TypeEq x y b The type cast succeeds causing its two argument types to be unified, or simply fails if the arguments are not unifiable. The type equality always succeeds "returning" HTrue if the arguments are syntactically equal, and HFalse if the arguments are not syntactically equal; thus the type equality will return false for two arguments which could be unified. If I understand correctly, these two classes do not provide a way to check for unifiability. Is it possible to write a class which checks to see if two given type arguments are unifiable? thanks, Jeff


text:
Reviews: Anonymous
- Anonymous
- India, Male, 25-30
- Novice Nomad
Nice location near Pigalle and Abesse metro stations..Also supermarket and other restaurants are nearby..Got a very nice welcome with champagne from Gerrard, who also gave some tips. The house owner always promptly replied to all our emails. It may be a bit difficult for older people to ride the stairs with heavy luggages. Good value for money as it was one of the cheapest appartments that I had found in a very nice location...Highly recomended for everyone..
- Anonymous
- India,
- Novice Nomad
The location of the place is nice and if someone wants to stay for a night it is a good enough place. An additional advantage is the free airport pick up and drop service. I booked a singe private room but ended up in the dorm due to some misunderstanding, as claimed by them. The juhu beach i was not very bored being a single traveller. It is a good place if one is travelling in a group for few days.
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text:
Conveen Optima Urisheaths With Collecting Bags Versus Absorbents
This study has been completed.
Coloplast A/S
Information provided by (Responsible Party):
Coloplast A/S
ClinicalTrials.gov Identifier:
First received: January 25, 2010
Last updated: September 16, 2011
Last verified: April 2007
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The objective of this investigation is to asses with validated scales, the impact on the quality of life of men suffering of moderate to severe incontinence of the use of Conveen Optima urisheath in comparison with their usual absorbent protection.
|Urinary Incontinence
|Device: Conveen Optima is a urisheath to be used together with a collecting bag for urine Device: absorbent protection
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Evaluation de l'Impact Sur la qualité de Vie de l'Utilisation d'un système Collecteur Conveen( étuis pénien Conveen Optima Avec Poches de Recueil Conveen) Chez Des Hommes Souffrant d'Une Incontinence Urinaire modérée ou sévère, Comparativement à Leur Protection Absorbante Habituelle
Further study details as provided by Coloplast A/S:
Primary Outcome Measures:
- Impact on quality of life [ Time Frame: Days 0, 15, 30 ]
Secondary Outcome Measures:
- Efficacy (leakages) [ Time Frame: days 13, 14, 15 and days 28, 29, 30 ]
|Study Start Date:
|June 2007
|Study Completion Date:
|March 2009
|Primary Completion Date:
|February 2009 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Conveen optima urisheaths
Device: Conveen Optima is a urisheath to be used together with a collecting bag for urine
Conveen optima urisheath is intended to be used together with a collecting bag for urine and to be changed on a daily basis
Placebo Comparator: absorbent protections
The patient use their usual absorbent protection as comparator. All brands are allowed.
Device: absorbent protection
The patient use his usual absorbent protection (same brand), and change it when needed
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patient over 18
- Out clinic patient
- Patient using absorbent protection for his urinary incontinence
- Moderate to severe urinary incontinence (1 hour pad test > 10g)
- All kind of stable urinary incontinence
- Patient able to apply himself the device
- Patient able to understand the questions
- Patient having given his informed consent
- Patient whose overall treatment for his urinary incontinence is not modified during the study
Exclusion Criteria:
- Patient having a retracted penis
- Patient having skin problem on the penis
- Patient using urisheaths
- Bedridden patient
- Institutionalized patient
- Patient with indwelling catheter or under intermittent catheterisation
- Patient with fecal incontinence leading to the use of absorbent protection
- Patient suffering of urinary tract infection
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01056666
Please refer to this study by its ClinicalTrials.gov identifier: NCT01056666
Sponsors and Collaborators
Coloplast A/S
|Principal Investigator:
|Pierre Costa, Professor
|Hôpital Caremeau Nimes. France
More Information
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Coloplast A/S
|ClinicalTrials.gov Identifier:
|NCT01056666 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 25, 2010
|Last Updated:
|September 16, 2011
Additional relevant MeSH terms:
Urinary Incontinence
Urination Disorders
Urologic Diseases
Lower Urinary Tract Symptoms
Urological Manifestations
Signs and Symptoms
Behavioral Symptoms
Elimination Disorders
Mental Disorders
ClinicalTrials.gov processed this record on September 21, 2017


text:
The Girls of Atomic City
For the women whose lives are documented in the new book "The Girls of Atomic City," a top-secret mission during World War II gave them a chance to make history at a time when there were few career options. Ray Suarez talks to author Denise Kiernan about the women who helped enrich fuel for the first atomic bomb used in war. Continue reading


text:
Research Topics
Hamid Reza Kianifar
Affiliation: Mashhad University of Medical Sciences
Country: Iran
Detail Information
- Malakoplakia of colon in a child with celiac disease and chronic granulomatous diseaseHamidreza Kianifar
Department of Pediatric Gastroenterology, Mashhad University of Medical Sciences, Iran
Indian J Gastroenterol 25:163-4. 2006..His nitro-blue-tetrazolium test was compatible with chronic granulomatous disease. In colonic biopsy Michaelis-Gutmann bodies were seen...
- D28G mutation in congenital glucose-galactose malabsorptionHamid Reza Kianifar
Department of Pediatrics, Mashhad University of Medical Sciences, Ghaem Medical Center, Ahmadabad Avenue, Mashhad, Iran
Arch Iran Med 10:514-8. 2007..Congenital glucose-galactose malabsorption is a rare autosomal recessive disorder of the intestinal transport of glucose and galactose, leading to watery diarrhea, dehydration, failure to thrive, and early death...
- 99mTc sestamibi imaging - can it be a useful substitute for hepatobiliary scintigraphy in infantile jaundice?Ramin Sadeghi
Department of Nuclear Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Ebn Sina Street, Mashhad, Iran
Nuklearmedizin 48:100-3. 2009..This property provides a hepatic excretory mechanism which is different from bilirubin excretion. In this study we evaluated the value of 99mTc MIBI in differential diagnosis of neonatal cholestasis...