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Guidance Documents (Medical Devices and Radiation-Emitting Products)
What is guidance?
Guidance documents are documents prepared for FDA staff, regulated industry, and the public that describe the agency's interpretation of or policy on a regulatory issue. Guidance documents include, but are not limited to, documents that relate to:
- the design, production, labeling, promotion, manufacturing, and testing of regulated products
- the processing, content, and evaluation or approval of submissions
- inspection and enforcement policies
Guidance documents do not create or confer any rights for or on any person and do not operate to bind FDA or the public. An alternative approach may be used if such approach satisfies the requirements of the applicable statue, regulations, or both.
Additional Information
- Search for official FDA guidance documents and other regulatory guidance for all topics
CDRH Fiscal Year 2017 (FY 2017) Proposed Guidance Development and Focused Retrospective Review of Final Guidance CDRH Fiscal Year 2016 (FY 2016) Proposed Guidance Development and Focused Retrospective Review of Final Guidance Recent Final Medical Device Guidance Documents Recent Draft Medical Device Guidance Documents Blue Book Memos - ODE Guidance Memoranda
- CFR Sec. 10.115 Good Guidance Practices


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Second, it seems as though the battery in my phone is acting up, just like my Droid 4 did. I'll charge it fully, the battery will drain over the course of the day, and then it will continue to live on critical (!) battery life for the next 5 hours until I go to bed and plug it in.
Why does it do this? Why does my phone apparently not understand the battery capacity? If my phone is getting down to the point where it says critical, with the red exclamation point in the battery icon, why does it continue to operate for 5 hours? How do I fix this?

subset: commoncrawl


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Boy Scout troop 318 recently honored Adam Woodward of Anoka at an Eagle Court of Honor at The Church of Jesus Christ of Latter-day Saints. He follows his five brothers and father to receive this honor.
Eagle Scout is the highest attainable rank in the Boy Scouts and requires years of dedication and hard work. Only 5 percent of all Boy Scouts attain this rank. Scouts must demonstrate proficiency in leadership, service and outdoor skills at multiple levels. They must earn 21 merit badges and must complete an extensive service project that he plans, organizes, leads and manages before his 18th birthday.
Woodward designed and constructed a patio for the hockey warming house at the Ramsey Central Park hockey rink for his Eagle Project. He led 15 volunteers in removing sod, creating a base and topping with paver stones in preparation for a finished patio. He says he learned the valuable lesson on preparing yourself before you are able to lead others. He credits the Scouting program for giving him a love for serving and for the outdoors.
He is attending Anoka-Ramsey Community College as a high school senior. He also is violinist in the Greater Twin Cities Youth Symphony and plays in a string quartet with the Augsburg College Suzuki Talent Education Program. He enjoys soccer, snowboarding and classical music. Woodward is the son of Scott and Jill Woodward.


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Foolish Goose Tracks
Foolish Goose Tracks is a free block of the month quilt finishing at 89″ x 106″. This BOM lasts for the next six months. The fabric requirements and first block have been posted already.
Be sure to check out Heather Finnell's blog too for construction tips.
Download Five FREE Quilt Block Tutorials:
Stay in touch ... Join my NEWSLETTER:
This post was published on January 29th, 2009. Post topics: Free Projects. Post tags: BOM, Full-Sized Quilts.


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DETECTIVES investigating a traumatic robbery where a woman was pulled to the ground have drawn up an Efit of a man they wish to speak to.
The 67-year-old woman was attacked by a man who was on a bike, as she walked to work on Queensway, Southend.
He was chased by a TNT lorry driver in a dramatic pursuit but the suspect got away.
Investigating officer DC Sam Boyd said: "The man grabbed the victim's bag and she was dragged to the ground. She tried to hang onto it and there was a struggle.
"She suffered extensive bruising to her right under arm and had large grazes on her right knee and right wrist. He got away with her bag and its contents. The victim has been left very shaken as a result of what happened.
The black bag contained the victim's mobile phone and purse. The suspect is described as aged between 21 and 40, had black, cropped, receding hair and was carrying a black canvas bag over his shoulder. He was riding a bike.
Anybody with any information about the attack, which took place at 11.45am on July 24, can call DC Sam Boyd at Southend CID via Essex Police 101 or they can call independent charity Crimestoppers anonymously on 0800 555 111.


text: Posted October 19, 2011 · Report post On this day 19th Oct in 1985, A-Ha went to No.1 on the US singles chart with "Take On Me", making them the first Norwegian group to score a US No.1. Let's face it, coming from Norway with its population of just a few thousand (well, just a bit over four million), this was some achievement. http://www.thisdayinmusic.com/pages/aha_take_on_me Share this post Link to post Share on other sites


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County Puts Tax Forfeited Property Up for Sale
ST. CLOUD – Stearns County is holding an auction to sell properties forfeited due to unpaid taxes.
Twenty-four properties will be auctioned off tomorrow (Wednesday) beginning at 7:00 p.m. at the Stearns County Service Center.
If you're interested in buying one of the properties you can go to the county's website to see a list of what's for sale. Each property is sold "as is" to the highest bidder and all sales are final. All sales also require 20% down.
If you have questions you can call the County Auditor's Office at 656-3900.


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Cover ups
The suspect was last seen wearing bud light 12-pack
Police in Lincoln, Neb., know one thing about the man who robbed the Kwik Stop convenience store on Monday: He has at least two vices. First, they know he likes cigarettes, because that was all he stole. He got about $50 worth. Second, he might like beer. Police suspect this because his disguise was an empty box from a 12-pack of Bud Light. Police have a lead, though, because he dropped the box as he fled. Police are checking for fingerprints.
Hey, Ezederick, is that you in there?
Police in Memphis have arrested Ezederick Jones, 18, on charges that he robbed a KFC on Saturday, reports the Memphis Commercial Appeal. Now, he hasn't been found guilty, but if he did it, here are the things he did wrong. First, he robbed a store where he used to work. There is almost always going to be someone there who remembers back when you used to work there. Second, he had just been fired the day before, so actually, pretty much everyone there remembered him. Third, he had a mask on, but the eye holes were extra large. It is unclear whether the robber had extra-large eyes, or maybe borrowed it from someone who did, but the holes were big enough that during the robbery, the manager addressed him by name. And when your name is Ezederick, good chance you've been made. He bolted, but police found him within hours.
Heavy Metal
All other units, be on lookout for unit
There would seem to be an inherent risk to personal property when one decides to attend a concert by Nine Inch Nails and Jane's Addiction. So it comes as no great surprise to learn that a car was stolen during the show in Mountain View, Calif., on Friday. The surprising part is that the car that was stolen was one of the Mountain View Police Department's patrol cars. Police looked for it Friday night and all day Saturday. Finally, a resident called on Sunday and said there was a stray police car parked in the lot at her apartment complex. Sure enough, that was it. And the shotgun was still safe and secure. Keys were missing, but how lucky do you think you're going to get?
Warm and Fuzzy
Exhibitionists show their heart
Organizers of an "Undies Run" at Chapman University in Orange, Calif., say that they collected the clothes shed by the 1,000 or so participants and donated them to a Ugandan orphanage. The orphanage burned down last summer, leaving 250 children with less than the nothing they already had. The run is not school sponsored and takes place twice a year, during finals week in winter and spring. The whole philanthropic angle of Wednesday's run was a nice counter to the last run, when students did $13,000 worth of damage to an old fountain.
Compiled from Times wire services and other sources by staff writer Jim Webster, who can be reached at firstname.lastname@example.com.


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- 2 teaspoons coriander seeds
- 2 teaspoons cumin seeds
- 2 teaspoons mustard seeds
- 2 teaspoons ground cloves
- 1 teaspoon turmeric
- 2-inch piece ginger, peeled and chopped
- 1/3 cup white vinegar
- In a spice or coffee mill grind spices and ginger until very-finely minced. Turn out into a bowl and stir in vinegar to make a smooth paste.
- To make curry oil, mix half of paste with 1 cup vegetable oil.
Recipe Details
- Source: Essence Of Emeril EE2162
- Dish Type: Sauces


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NEW YORK (TheStreet) -- U.S. stocks were sliding amid weakness in the international markets and as second-quarter earnings season unfolds.
Ongoing chatter about an earlier-than-expected rate hike by the Federal Reserve continues to underpin market caution. With the job market appearing to gather steam, more and more investors are starting to expect that the U.S. central bank must expedite its timetable for scaling back its ultra-loose monetary policy.
Despite recent stronger-than-expected jobs data, the Labor Department's Job Openings and Labor Turnover survey for May showed little movement. The survey indicated 4.6 million job openings on the final business day of May, little changed from 4.5 million in April. Likewise, a hires rate of 3.4% and separations rate of 3.2% barely moved over the month.
The Dow Jones Industrial Average was down 0.78% to 16,891.5. The S&P 500 retreated 0.82% to 1,961.38. The Nasdaq dumped 1.6% to 4,380.42.
July 8 Premarket Briefing: 10 Things You Should Know
Stock Market Today: Stocks' Record Run Ends on Eve of Earnings Season
European Stocks Fall on U.K. Manufacturing Slump
Second-quarter earnings season unofficially begins Tuesday after the markets close with the announcement of Alcoa's (AA) results. The aluminum maker is forecast by Wall Street to report second-quarter earnings 12 cents a share on revenue of $5.66 billion.
The U.S. market calendar on Tuesday includes Consumer Credit for May at 3 p.m. EDT.
European stocks continued to lose steam on Tuesday, as disappointing corporate news and an unexpected U.K. manufacturing slump caused some jitters. Furthermore, German imports and exports declined more than expected in May, signaling a weakening of Europe's largest economy.


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Anton wrote: > I repost here my original question "Why it no uses indexes?" (on > partitioned table and ORDER BY indexed_field DESC LIMIT 1), if you > mean that you miss this discussion. As I said back then: The planner isn't smart enough to push the "ORDER BY ... LIMIT ..." below the append node. -- Heikki Linnakangas EnterpriseDB http://www.enterprisedb.com
Next: From: Tom Lane Date: 2007-10-27 13:15:02 Subject: Re: Speed difference between select ... union select ... and select from partitioned_table Previous: From: Anton Date: 2007-10-27 08:53:30 Subject: Re: partitioned table and ORDER BY indexed_field DESC LIMIT 1
Next: From: Simon Riggs Date: 2007-10-27 09:24:29 Subject: Re: pgsql: Allow an autovacuum worker to beinterrupted automatically when Previous: From: Simon Riggs Date: 2007-10-27 08:53:45 Subject: Re: WAL archiving idle database


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Randomized Study of Not Giving Diphteria-tetanus-pertussis Vaccination With or After Measles Vaccination
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
In non-randomized studies, routine childhood vaccinations have been observed to have non-targeted effects. Difteria-tetanus-pertussis (DTP) vaccine provided with or after measles vaccine (MV) is associated with increased mortality in areas with herd immunity to pertussis.
We will examine in a randomised study of 6000 children the effect of not administering DTP simultaneously with or after MV on overall child mortality, hospitalization rates, and the immunological responses after vaccination. We will also examine potential sex-differential effects in the outcomes and interactions with other vaccines, other health interventions and season.
|Mortality Hospitalization Adverse Events
|Biological: DTP3/4+OPV+MV versus OPV+MV or DTP4+OPV4 versus OPV4
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
|Official Title:
|Diphteria-tetanus-pertussis (DTP) Vaccination and Child Survival: Randomized Study of Not Providing DTP Vaccination Together With or After Measles Vaccination
- Mortality till 4 years of age [ Time Frame: June 2011 ]
- Hospitalisations till 4 years of age [ Time Frame: June 2011 ]
- Adverse events 1 month after intervention [ Time Frame: December 2008 ]
- Immunological responses [ Time Frame: July 2008 ]
- Morbidity [ Time Frame: June 2011 ]
|Study Start Date:
|October 2005
|Study Completion Date:
|December 2011
|Primary Completion Date:
|December 2011 (Final data collection date for primary outcome measure)
Biological: DTP3/4+OPV+MV versus OPV+MV or DTP4+OPV4 versus OPV4
Background: Infectious diseases are the main cause of high child mortality in Africa. In several non-randomised studies, routine childhood vaccinations have been observed to have non-targeted effects. Live vaccines like measles vaccine (MV) seem to protect against overall mortality, whereas killed vaccines, like DTP, may have no beneficial effects, especially for girls. DTP provided with or after MV may be associated with increased mortality. The mechanisms behind these effects are unknown.
Hypothesis: Not providing DTP together with or after MV is associated with a 35 % reduction in overall mortality and 23% reduction in hospitalizations.
Objectives: To examine in a randomised study of 6000 children the effect of not administering DTP simultaneously with or after MV on
- Overall child mortality
- Hospitalization rates and major causes of hospitalization
- The immunological profile after vaccination
- Sex-differences in the above mentioned outcomes
Surveillance system: BHP's demographic surveillance system in Bissau covers 6 districts with a population of 90,000; 3,500 children are born each year.
Hospitalizations: There is only one pediatric ward in Bissau and all hospitalizations are identified in the BHP register.
Vaccinations: Vaccinations are provided and registered at the 3 health centres in the study area.
Intervention: In this study 6000 children are randomised as they come to receive DTP3 or DTP booster with or after measles vaccination (MV) at the local health centres. Children will be randomised to DTP3+OPV3 and MV versus OPV3 and MV or DTP4+OPV4 versus OPV4 (booster doses).
Follow-up: The children will be followed until 4 years of age or end of study.
- Adverse effects: In the first month after vaccination, 1000 children will be visited daily for three days and then weekly to register morbidity and consultations.
- Hospitalizations: The children will be followed at the pediatric ward.
- Mortality: Children will be followed by the routine surveillance system. Furthermore, all children will be visited yearly and finally when they reach four years of age. When a death is detected, a physician will conduct a verbal autopsy.
Sample size: With a total of 7500 person-years of follow-up, we will be able to document a 35% reduction in mortality and a 23% reduction in hospitalizations. A subgroup of children will be examined for possible differences in immunological profile after vaccination.
Ethical considerations: Herd immunity to pertussis should not be affected as, due to the intervention, more children is vaccinated.
|Ages Eligible for Study:
|9 Months to 4 Years (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- The child should be missing DTP3 or DTP4
- The child should have received DTP2
- The child should have received MV already or receive MV on the day of enrolment
Exclusion Criteria:
Normally applied contraindications for receiving vaccinations, including high fever
Please refer to this study by its ClinicalTrials.gov identifier: NCT00244673
|Bandim Health Project, Apartado 861
|Bissau, Guinea-Bissau
|Principal Investigator:
|Peter Aaby, DMSc
|Bandim Health Project
|Responsible Party:
|Bandim Health Project
|ClinicalTrials.gov Identifier:
|NCT00244673 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 25, 2005
|Last Updated:
|February 25, 2012
Keywords provided by Bandim Health Project:
Child mortality
Non-specific effects
Additional relevant MeSH terms:
Corynebacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


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Lincoln couple arrested for breaking into Etowah Co. house
A Lincoln couple was arrested{}after deputies said they broke into an Etowah County{}house July 27.
Below is{}a news release from the Etowah County Sheriff's Department detailing the charges:
A Lincoln couple was arrested and charged in connection to stolen property, according to Sheriff Todd Entrekin.
"Sean Patrick Boozer, 33, and Jessica Rochelle Baker, 35, both of Lincoln, are each charged with one count of third degree burglary and one count of second degree theft of property, both are felonies," says Investigator Jason Argo.
Boozer and Baker allegedly broke into a house, on Saturday, July 27, located on Coates Bend Circle.
Deputy Bradley Saylor received a phone call from a witness, who passed by the residence, stating that he believed the home was being broken into. Deputy Saylor arrived at the home within minutes of the call and found Baker sitting inside a pickup truck in the residence's driveway.
Baker stated that the truck was broken down and her boyfriend, Boozer, had gone to buy a new battery. When Deputy Shari Bellew arrived to assist Deputy Saylor they found the back door of the residence kicked in and upon further searching, found Boozer hiding in a bush with a concealed pistol on his ankle.
"Boozer has also been charged with one count of illegal carry of a concealed gun," says Deputy Saylor.
The duo was also in possession of a bag, which had the home owner's name and address printed on it and four antique canisters.
Boozer and Baker are currently being detained in the Etowah County Detention Center. Boozer is being held on $6,000 bond and Baker has a $5,000 bond. Baker also has an outstanding traffic warrant in Chilton County.


text:
Open to Options
Preparing to Make a Treatment Decision at Your Next Doctor's Visit?
We can help!
We can help!
Our Calendar
Download our latest calendar for a comprehensive list of everything that is going on at the Cancer Support Community.
Support Cancer Support Community Atlanta and get a pair of stylish, lightweight (and eco-friendly!) kigo footwear
A portion of each sale in November benefits CSC Atlanta!
Kigo footwear is celebrating the 2012 holiday season by donating a portion of all online sales to nonprofit organizations that are making a difference through their efforts to keep people healthy and empowered.
Between November 12 and 30, the Cancer Support Community Atlanta
will receive 20% of every purchase made by Kigo.
Check out the kigo footwear Gratitude & Giving page to read praises from customers who love the shoes
for everything from travel, to tai chi, to everyday adventures.
Learn more and get your own pair of kigos from their website!
If there is anything that The Cancer Support Community can do for you,
please do not hesitate to contact us.
The Cancer Support Community Atlanta
5775 Peachtree Dunwoody Road, Building C, Suite 225, Atlanta, GA 30342 · (404) 843-1880 · email@example.com


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J&J Ordered to Pay $14M in Pelvic Mesh Lawsuit
A jury in Philadelphia docked Ethicon, a subsidiary of Johnson & Johnson, $14m in a case regarding its pelvic mesh products.
About the Trial Against Johnson & Johnson
According ot MassDevice, Sharon Carlino, the plaintiff in the case, was awarded $3.5 million in compensatory damages and $10 million in punitive damages.
The jury found that the transvaginal polypropylene tape implanted during the plaintiff's 2005 hysterectomy was defective and Ethicon did not properly advise of the risks associated. She needed three surgeries to remove the mesh that had eroded.
Late last year, a similar case in the same court added $7 million in punitive damages to the $5.5 million in compensatory damages against Ethicon.
Ethican spokeswoman, Samantha Lucas, believes they have a strong ground for appeal.
Statistics on Defective Medical Devices
- In 2013, the U.S. food and Drug Administration (FDA) 63 high-risk devices. This represents an alarming increase of 350% compared to only five years prior.
- Between 2008 and 2011, 45% of medical device recalls involved due manufacture defects.
- 29% medical devices recalled between 2008 and 2011 malfunctioned during use or failed to provide intended results.
- Between 2005 and 2010, regulators received more than 4,000 reports of complications that were linked to transvaginal mesh devices..
- In the statement made by the FDA in 2011, it was suggested that transvaginal mesh devices were not as effective an option as traditional procedures used to treat pelvic organ prolapse and stress urinary incontinence. In addition to being less effective, they carried a far greater risk of injury.


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Jerusalem (Feb. 2)
(Jewish Telegraphic Agency)
The British air station at Gaza constructed by the Jewish labor cooperative, Solel Boneh, has been completed and turned over to the government.
Under the contract, the Solel Boneh had to complete the work within two months. The station covers an area of 40×30 meters. Forty workers were employed during the construction.
The government expressed satisfaction with the station.
In behalf of historic accuracy alone, with no desire to prolong a discussion on a subject alrady happily concluded, may I be permitted to correct several statements made by my good friend Dr. Wolsey, in regard to my letter of January 26th. The facts I presented in my letter were unassilable, though Dr. Wolsey chooses to interpret them from his own point of view. Dr. Wolsey questions my use of Rabbi Silver's name as one who spoke against the resolutions of the Social Justice Commission, yet he admits that Rabbi Silver suggested some other phrasing of one of the principles. It was exactly to change the phrasing of the resolution which caused the whole discussion. The mere act of suggesting a change which might run all the way from a negative to a qualifying word or phrase, indicates opposition to a matter under debate.
Dr. Wolsey does me the honor to quote from my study of the Workingmen and the Synagogue, but he fails to note that his references applied mainly to what I found the workingmen said about the Synagogue, but in no part of the study can there be found a single phrase that suggests that the Synagogue change its fundamental function of unifying and organizing all Jews on a basis of religious equality, for the sake of attacting the working people. We want them, we need them, we are getting them without endangering the cause of unity in Israel. My opposition to the report of the Commission at the Cleveland Convention grew out of my previous study of the question and a close analysis of my present attitude will disclose its harmony with my previous views. Whether Dr. Wolsey was serious or humorous in his references may be difficult to determine, but it is significant that he admitted having carefully read my paper and connected it with the report of his commission, which cannot justly be described as a joke on me.
As a parliamentarian, Dr. Wolsey is absolutely incorrect in charging me with "denaturing principle 7." The Convention did whatever denaturing was done. It is true, some of it was done at my suggestion, but when my suggestion of a change of phrase was overwhelmingly adopted, it became and is the voice of the Convention.
Dr. Wolsey is incorrect in calling my statement of Dr. Lee K. Frankel's request to withdraw his name from the report, "absolutely untrue." I wrote: "When Dr. Wolsey stated that the Commission desired that the adoption of the resolutions imply the en Jorsement of the long preamble also, Dr. Lee K. Frankel, a member of the Commission with drew his signature to the report." That ## absolutely true statemetn. But it is fair to add, which I did not record in my first letter both because it was not vital to my purpose and because it reflected upon the Chairman's own judgment and authority, the following fact: Dr. Frankel did not press the withdrawal of his signature to the report as explained by Dr. Wolsey, simply because Dr. Wolsey withdrew his own interpretation of the whole report, holding argument and resolutions as being essentially and logically interrelated. With regard to the actual phrasing of principle No. 6 which Rabbi Wolsey claims I misstated, from my own notes made on the Convention floor and read to and adopted by the Convention. I have the following: "The duty of the Synagogue and its pulpit to speak courageously on all human rights as part of its prophetic function."
A fair and friendly view of the whole episode would be the following: The authors and friends of the Social Justice Report suggested to the Convention the adoption of the report as first presented. In the course of the discussion a large number of delegates suggested changes of phrases, modifications of sentences, etc. The Convention listened and finally decided that the original resolutions must not pass. The Convention is to be congratulated and we must be satisfied for the present with the results as far as the Union of American Hebrew Congregations is concerned.
SOLOMON FOSTER. Rabbi of Temple B'nai Jeshurun. Newark. N. J., Feb. 1. 1927.


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A followup to my previous [reddit version]:
The examples are of limited utility. The problem is not a few bad apples or a few bad words; were that the case it would be easier to address. The problem is a subtle one: it's in the tone and tenor of conversation, it's in the things not talked about, in the implicitization of assumptions, and in a decentering of the sorts of communities of engagement that Haskell was founded on.
Back in 2003 and 2005, communities like Haskell Cafe were communities of praxis. That is, we gathered because we do Haskell, and our gathering was a way to meet others who do Haskell. Our discussions were centered on this praxis and on how we could improve our own doing of Haskell. Naturally, as a place of learning it was also a place of teaching— but teaching was never the goal, teaching was a necessary means to the end of improving our own understandings of being lazy with class. The assumptions implicit in the community at the time were that Haskell was a path to explore, and an obscure one at that. It is not The Way™ by any stretch of the imagination. And being a small community it was easy to know every person in it, to converse as you would with a friend not as you would online.
Over time the tone and nature of the Cafe changed considerably. It's hard to explain the shift without overly praising the way things were before or overly condemning the shift. Whereas the Cafe used to be a place for people to encounter one another on their solitary journeys, in time it became less of a resting stop (or dare I say: cafe) and more of a meeting hall. No longer a place to meet those who do Haskell, but rather a place for a certain communal doing of Haskell. I single the Cafe out only because I have the longest history with that community, but the same overall shift has occurred everywhere I've seen. Whereas previously it was a community of praxis, now it is more a community of educationalism. In the public spaces there is more teaching of Haskell than doing of it. There's nothing wrong with teaching, but when teaching becomes the thing-being-done rather than a means to an end, it twists the message. It's no longer people asking for help and receiving personal guidance, it's offering up half-baked monad tutorials to the faceless masses. And from tutorialization it's a very short path to proselytizing and evangelizing. And this weaponization of knowledge always serves to marginalize and exclude very specific voices from the community.
One class of voices being excluded is women. To see an example of this, consider the response to Doaitse Swierstra's comment at the 2012 Haskell Symposium. Stop thinking about the comment. The comment is not the point. The point is, once the problematic nature of the comment was raised, how did the community respond? If you want a specific example, this is it. The example is not in what Swierstra said, the example is in how the Haskell community responded to being called out. If you don't recall how this went down, here's the reddit version; though it's worth pointing out that there were many other conversations outside of reddit. A very small number of people acquitted themselves well. A handful of people knew how to speak the party line but flubbed it by mansplaining, engaging in flamewars, or allowing the conversation to be derailed. And a great many people were showing their asses all over the place. Now I want you to go through and read every single comment there, including the ones below threshold. I want you to read those comments and imagine that this is not an academic debate. Imagine that this is your life. Imagine that you are the unnamed party under discussion. That your feelings are the ones everyone thinks they know so much about. That you personally are the one each commenter is accusing of overreacting. Imagine that you are a woman, that you are walking down the street in the middle of the night in an unfamiliar town after a long day of talks. It was raining earlier so the streets are wet. You're probably wearing flats, but your feet still hurt. You're tired. Perhaps you had a drink over dinner with other conference-goers, or perhaps not. Reading each comment, before going on to the next one, stop and ask yourself: would you feel safe if this commenter decided to follow you home on that darkened street? Do you feel like this person can comprehend that you are a human being on that wet street? Do you trust this person's intentions in being around you late at night? And ask yourself, when some other commenter on that thread follows you home at night and rapes you in the hotel, do you feel safe going to the comment's author to tell them what happened? Because none of this is academic. As a woman you go to conferences and this is how you are treated. And the metric of whether you can be around someone is not whether they seem interesting or smart or anything else, the metric is: do you feel safe? If you can understand anything about what this is like, then reading that thread will make you extremely uncomfortable. The problem is not that some person makes a comment. The problem is that masculinized communities are not safe for women. The problem is that certain modes of interaction are actively hostile to certain participants. The problem is finding yourself in an uncomfortable situation and knowing that noone has your back. Knowing that anyone who agrees with you will remain silent because they do not think you are worth the time and energy to bother supporting. Because that's what silence says. Silence says you are not worth it. Silence says you are not one of us. Silence says I do not think you are entirely human. And for all the upvotes and all the conversation my previous comment has sparked on twitter, irc, and elsewhere, I sure don't hear anyone here speaking up to say they got my back.
This is not a problem about women in Haskell. Women are just the go-to example, the example cis het middle-class educated able white men are used to engaging. Countless voices are excluded by the current atmosphere in Haskell communities. I know they are excluded because I personally watched them walk out the door after incidents like the one above, and I've been watching them leave for a decade. I'm in various communities for queer programmers, and many of the folks there use Haskell but none of them will come within ten feet of "official" Haskell communities. That aversion is even stronger in the transgender/genderqueer community. I personally know at least a dozen trans Haskellers, but I'm the only one who participates in the "official" Haskell community. Last fall I got hatemail from Haskellers for bringing up the violence against trans women of color on my blog, since that blog is syndicated to Planet Haskell. Again, when I brought this up, people would express their dismay in private conversations, but noone would say a damn thing in public nor even acknowledge that I had spoken. Ours has never been a great community for people of color, and when I talk to POC about Haskell I do not even consider directing them to the "official" channels. When Ken Shan gave the program chair report at the Haskell symposium last year, there was a similarly unwholesome response as with Swierstra's comment the year before. A number of people have shared their experiences in response to Ken's call, but overwhelmingly people feel like their stories of being marginalized and excluded "don't count" or "aren't enough to mention". Stop. Think about that. A lot of people are coming forward to talk about how they've been made to feel uncomfortable, and while telling those stories they feel the need to qualify. While actively explaining their own experiences of racism, sexism, heterosexism, cissexism, ablism, sanism, etc, they feel the simultaneous need to point out that these experiences are not out of the ordinary. Experiencing bigotry is so within the ordinary that people feel like they're being a bother to even mention it. This is what I'm talking about. This is what I mean when I say that there is a growing miasma in our community. This is how racism and sexism and ablism work. It's not smacking someone on the ass or using the N-word. It's a pervasive and insidious tone in the conversation, a thousand and one not-so-subtle clues about who gets to be included and who doesn't. And yes the sexual assaults and slurs and all that factor in, but that's the marzipan on top of the cake. The cake is made out of assuming someone who dresses "like a rapper" can't be a hacker. The cake is made out of assuming that "mother" and "professional" are exclusive categories. The cake is made out of well-actuallys and feigned surprise. And it works this way because this is how it avoids being called into question. So when you ask for specific examples you're missing the point. I can give examples, but doing so only contributes to the errant belief that bigotry happens in moments. Bigotry is not a moment. Bigotry is a sustained state of being that permeates one's actions and how one forms and engages with community. So knowing about that hatemail, or knowing about when I had to call someone out for sharing titty pictures on Haskell Cafe, or knowing about the formation of #nothaskell, or knowing about how tepid the response to Tim's article or Ken's report were, knowing about none of these specifics helps to engage with the actual problem.


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Born from the need for an innovative plumbing fixture studio in the greater St. Louis metropolitan area, Immerse provides contractors, designers and builders with a new way to see, touch and feel alternative plumbing products.
Immerse's parent company, Atlas Supply was founded in 1937 by Fred and Ben Suffian and has remained a family business since its beginning. During the 1960's Fred and Ben's children joined their parents, successfully running the company for many years. During the mid-1990's, grandchildren, Brent, Joel and Leigh joined the Atlas team.
During Atlas' 70+ years in business, loyal clients, including local contractors, designers, builder and remodelers desired an offsite space and selection center for their personal and client needs – no true interactive and experiential plumbing showroom existed.
In 2011, Atlas and the Suffian family embraced the idea, wanting to provide the design community with a completely new experience to interact with plumbing fixtures. Immerse was born.
While most showrooms are mandated by vendors who control the design process and the selection of products, Immerse's concept was developed to be different. Not bound by constraints, we utilized local resources to create a stylish, inspiring environment that would give customers a space that would allow them to push their creativity to the limit. Immerse's lines are fresh, yet tried and true and easily supported. After all, plumbing is truly both form and function.


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Im 5'1 Tall my Weight is 150 and Im a 32b I Thinking of Getting 350cc Will I B a Full C?
Doctor Answers 7
Implant Size
1. Dimensional planning
2. Gel Implant Sizing system
Dimensional planning – The measurements of your chest wall are taken. Also, the breast dimensions including the height, width, and current dimensions of each breast form the basis of dimensional planning. Based on these measurements, the implant size is recommended. This will give you a unique breast implant that is suited for your body frame. However, there are some limitations of what size we can recommend. For instance, some implants may just be too big for a narrow chest wall. Your surgeon can review this with you during the consultation.
Gel Implant Sizing system – During the preliminary breast implant consultation, you will be provided with an option to "try on" a variety of implant shapes and sizes. You can also visualize the possible outcomes of your surgery which helps you to get that perfect size to give you the shape that you longed for. This way your preferences are known and you can then pick a range of implants that will "fit" just right to give a soft natural fuller look. Hope this helps.
Implant Selection Process
In order to make an accurate size recommendation, I would need to assess your chest wall and breast mound measurements and characteristics. Unfortunately, there is not a general rule of thumb or objective criteria to implant selection.
Your plastic surgeon will perform several measurements of your chest wall and breast anatomy and determine a range of implants that both fit your chest wall and reach your desired goals.
The next step is to try on this range of implants in the office with your doctor. The key to this success is showing your surgeon the body proportion you desire with a bra sizer and allowing your surgeon to guide you to the right implant. It will be much easier to communicate in implant cc's than cup size when determining the appropriate implant for you.
I wish you a safe recovery and fantastic result.
Dr. Gill
Learn more: http://www.drpaulgill.com
350 C cup
You are in the ballpark as they say.
5'1,150 lbs, B cup. If you have a 350 cc implant you will probably be a full C cup. Disscuss this fully with a board certified plastic surgeon when you consult with him/her.
You might also like...
How do you translate cup size to implant volume size?
When we discuss breast surgery with patients we often talk about cup sizes. It is important to remember that cup sizes are somewhat arbitrary and a C at one store may be a D at another. That being said, it does allow us to start to focus or an endpoint. For breast augmentation, the ideal implant depends on many things including the patient's medical history, specific breast measurements and ultimately the patient wishes. Seek consultation with a board certified plastic surgeon who can help educate you about these important decisions
Breast Implant Size: Individual decision not just numbers
Choosing a breast implant that is the right size for you and your frame has multiple variables that are not all numeric. The amount of pre-existing breast tissue, skin quality and breast shape all factor into how an implant fits under the breast. There are different shapes and heights that enable a huge number of combinations, however the right combination is what you and your board certified plastic surgeon has discussed. The size sounds about right though.
Learn more: http://www.drtrussler.com
Cup size after implants
You should be about a C cup, however this is only an educated guess. The guess would be more accurate if you posted any photographs. The final cup size depends on a large number of factors including the dimensions of your breast and chest-wall.
350 cc breast implants may be too large for you.
How to pick breast implant sizes
Article by George J. Beraka, MD
Manhattan Plastic Surgeon1) This is the most common type of question on RealSelf.
2) It is the surgeon's job to pick the right breast implants, not the patient's. Implant selection is really pretty technical.
3) Make sure your surgeon REALLY understands the look you want. Mentioning a cup size is not enough. Show your surgeon pictures of breasts you like.
4) Then your surgeon has to tell you if your chosen look is realistic for your anatomy. The most common mistake is to go too big.
5) I recommend that the surgeon NOT make a final implant choice in advance, because this is just an educated guess.
6) The surgeon should have a large inventory of different size and shape implants available in the operating room.
7) Then the surgeon can put sterile disposable implant SIZERS in your breasts during surgery, to see what a particular implant really looks like inside you. This is how to make the best choice. A sizer costs only $45, and takes all the guess work out.
8) Finally, the sizer is discarded, and the correct breast implants (based on what you want and on your anatomy) are opened from the operating room inventory, and put in your breasts to complete the operation.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Average Customer Rating
(based on 5 reviews)
of respondents would recommend this to a friend.
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By greek_oris
from Greece
Amazing photo....
Was this review helpful? Yes / No
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Cool atmospheric picture
By Cyclesue
from Cumbria
I have framed this in a black frame and it looks really striking on my bedroom wall. Really pleased with the quality of the print and the size is standard poster size- this is good as you can get cheap frames from homeware stores.
Bottom Line Yes, I would recommend this to a friend
i would buy this product again.
By steve h
from uk
(2 of 2 customers found this review helpful)
Great pic of the tower!
By John
from Singapore
My only comment is that here in France, the nearest standard size for frames seems to be 60x80 so I had to cut this down a bit to fit the frame. Otherwise, very happy with purchase.
unusual - quite classy
Unusual and quite classy
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Donald asks…
Can anyone suggest good blogs about gardening and lawncare?
I am interested in finding cool blogs about gardening and lawncare. Most od the blogs Ive found so far are pretty lame.
GardenersCardiff answers:
Hey Matty D,
South Carolina has the Emmy Award-winning "Making It Grow!", which is a live, interactive call-in program produced by ETV and Clemson University, serving viewers with current research-based horticultural information. Host Rowland Alston, Jr., and featured guests focus on gardening topics, while highlighting interesting places and products from around the state.
The chat is open at various times.
Linda asks…
I am looking for some PA gardening websites and blogs?
I am trying to find some good websites and blogs about PA gardening? I am interested in Flower gardening as well as Vegetable gardening. I have done the google thing and I just can't seem to find any good websites or blogs to bookmark and come back to. Please let me know if there are any and what they are? Thank you in advance!
GardenersCardiff answers:
The BBC one is very good. It has categories of what you can post:
If you're looking for the more blog-type gardening website, then try out this one:
Hope this helps
William asks…
Could you help me find a good gardening blog?
I really like faires, and lawn gnomes and stuff like that to be involved with my garden's style. Any gardening blogs would be great. I just want something to give me ideas for this coming growing season. Thanks a ton!
GardenersCardiff answers:
I loooove The Garden Witch. She always keeps it updated with gorgeous pictures and she has lots of fabulous paintings of fairies. I even bought a poster of one from her to put on my wall!
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The inimitable Richard D. James, normally infallible, had things surprisingly wrong with the track "Plenty Harmonium." Not only are we, as a species capable of hearing, lacking an overabundance of harmonium, but there isn't even enough to satiate the residents of a small town. Forget the overwhelming human benefit of a natural resource like water, or the tremendous increase in the quality of life that manufactured drugs like penicillin have brought; the world needs more harmonium! Those extremely depressing TV advertisements telling you to send a lonely buck to an impoverished child in Africa? Forget it! Dispatch that kid a harmonium, or a recording of a harmonium, and all will be well. If cultural tensions arise, said parcels can always be used as a bargaining chip with neighboring warlords.
Certainly doing his part to unleash a (benign) plague of harmonium on the world, Jaime Fennelly a.k.a. Mind Over Mirrors will be releasing a new LP, When the Rest Are Up at Four, on September 17 via Immune Recordings. As if it wasn't made clear enough in the preceding paragraph, Fennelly's instrument of choice takes the form of an Indian pedal harmonium, manipulated through the use of an array of oscillators, tape delays, phasers, and miscellaneous other synthesizing processors.
To what end, you might ask? A press release talks about an ebb and flow made apt by the instrument's "popularity among islanders," but on a more straightforward level, I'm hearing via SoundCloud an enveloping throwback to the 19th century, combined with an aesthetic not too far away from Daniel Lopatin's output. Enlightening media incoming…
• Mind Over Mirrors: http://mindovermirrors.tumblr.com
• Immune: http://immunerecordings.net
More about: Mind Over Mirrors


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A San Diego hotel's average occupancy rate is 79%. With a typical property having approximately 200 rooms that leaves 42 rooms per night as non-revenue generating. If the average room rate is $150, this property will loose $6,300 every day or $44,100 every week or $176,400 every month equaling approximately $2,116,800 every year. OUCH! Once lost, there is no way to recover that potential business or what those additional funds could have accomplished - facility upgrades, employee incentives, advertising programs to increase occupancy rates, owner's/investors profits, etc. Over a period of years this loss is staggering!
Lets reverse the industries - radio, TV, billboards, newspapers, magazines convert your unsold, space inventory into hotel rooms to use in business, promotions, employee incentives, cash conversion, etc. Turn your unsold inventories into cash generation and expense savings!


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*Please Note: Available in 2 Colours - Halophane Clear and Halophane Frosted.
The 8044 9" Glass Shade in Clear is an elegant and graceful shade. The colour of the glass is halophane clear. This shade will be a home decor classic.
The 8044 9" Glass Shade in Clear has the following product features:
- Shade Colour: Halophane Clear.
- Material: Glass.
- Dimensions:
- Height - 155mm.
- Width - 230mm.
- Fitter Size - 55mm (2¼").
- Suitable to be used with Table Lamps, Floor Lamps and Pendant Lights.
- ASA: Australian Standards Approved.
- Condition: Brand new in manufacturer's packaging.
*Please note: This range of glassware is either hand blown or mould-formed, therefore small detail may vary between batches.
At MICA Lighting you can purchase from a huge range of fabric shades, glass shades & metal shades. Replace your existing lamp shade to give your room an updated look. Choose from a range of coloured fabrics, textures and styles.
Updating your decor has never been easier, as we have a very comprehensive range of modern lamp shades, traditional lamp shades, art deco lamp shades, etc. These are adaptable to most table lamps, floor lamps and pendant lights.
This product is offered with a "Dead On Arrival" warranty. If found D.O.A. the product shall be replaced, otherwise, there is no warranty on shades.
All items warranty are covered by MICA Lighting, therefore should you have any trouble with your item, you only need to contact us. MICA Lighting, shall look after the warranty for you. Please use our "Contact Us" form and we shall attend to your requirements promptly.
*Please Note1: Warranties are deemed void:
- If not installed by a licenced electrician (DIY products exempt), and / or
- If the product has been modified or tampered with in any way.
*Please Note2: These Warranty Conditions should be read in conjunction with our Standard Terms and Conditions.
Opening Hours: Tuesday - Saturday 9am-5pm.
Phone: 1300 GOMICA (466 422).
Address: Factory 8, 4 Metrolink Circuit West (Corner Cooper Street), Campbellfield, Victoria 3061.
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Take a bite out of this ORLY Green Apple Nail Lacquer. This trendy cream green shade looks as if you just picked it off a tree and will leave your tips and toes looking as fresh as the green gables in the countryside.
As one of the nail care industry's renowned colour houses, ORLY introduces new collections each season to keep you en-trend and in style. ORLY Green Apple Nail Lacquer is free of DBP, toluene, formaldehyde and features their award-winning gripper cap for fuss-free application every time.
Please remember to add postal time (2-3 working days) to obtain a complete estimate of delivery to your door.
You will receive an email to confirm when your item has been sent.
You can also check the status of your order and individual items by accessing My Account details and following the prompts.
Please allow 10 working days from dispatch of your order before notifying us of any late deliveries.
It may be advisable to check with your neighbours to see if a parcel has been left with them, check any outhouses you might have where it may be left if it cannot fit through your letterbox and contact your local sorting office to see if the item has been returned to the depot as undelivered and awaiting collection.
Please see our returns policy.
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Alfred Hitchcock: The Masterpiece Collection
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- //Home
- //Music
- //Reviews
- //George Benson
Few guitarists can match the resume of one George Benson. The guitarist has been plying his trade for the better part of several decades now but still is intent on changing with the times, rolling with the punches, or any other adage that means adapting and coping. Benson's worst enemy could often be himself as the horde of material he's released (studio and compilations) would make several labels pull their hair out. Nonetheless, he keeps putting things out there and his latest album is no different. With the help of several contemporary writers, including one who has worked with "boy bands" like O-Town, Benson makes this disc work sporadically with some highly slick studio polish.
Opening with "Six Play", the album has a definitive soulful and urban sound, comparable to several soul singers like D'Angelo and R. Kelly. The light and airy female vocals work in tandem with Benson's intricate guitar work. Judging by this song alone, one gets the feeling he's after something Santana and, more recently, Toots & the Maytals are after—getting help to make everything flow. The only difference is this is basically lacking the big names. Benson resembles a bit player on this track as the romantic, turn-the-lights-down-low effort saunters along. "Whole Man" comes off as genuine and not quite as forced, with Joshua Thompson adding guitars and Melvin Davis on Hammond organ. The lyrics are also far better, resulting in the song's melody and chorus being an early high point a la Luther Vandross.
George Benson
US: 25 May 2004
UK: 15 Mar 2004
Benson's guitar work is buried deep in each of these songs, especially on the slow and tender title track. With bits of acoustic guitar, a pinch of keyboard, and a drum-programming sample, Benson gets strong backing harmonies also. It's the type of song that K-Ci & Jo-Jo would have to think about covering. Another plus is, despite the sampling, the rather smooth yet heartfelt groove Benson usually creates. The first snafu, though, is "Loving Is Better Than Leaving", opening with a bit of talk that too often ruins current R&B ditties. Talking about being played over a bland arrangement, Benson creates a style that has been done to death. "Who would've thought I'd ever see my lady dirty dance with another man", Benson sings. Whatever. "Cell Phone", which comes later on, falls into a similar bland rut despite the pretty duet. "Can a cell phone reach to heaven?" they sing, which might ring true (excuse the pun) in some spots, but not here.
"Strings of Love" fares better, resembling Sting circa "Fragile" to a certain extent. The flamenco touches on guitar create a delicate sound that is part soul and part "world" music. Unfortunately, Benson isn't given much solo work in terms of either his voice or guitar letting loose over a period of time. Several solos should be given with either instrument, including the sultry "Black Rose" with its orchestral touches. Here Benson is finally given a bit of time to shine, but he works in tandem with the lush sounds, rarely venturing into unknown territory. The meticulous style he uses brings to mind a calmer Jeff Beck or Clapton. "Stairway to Love" is probably one of the nuggets offered up despite the rather insipid lyrical content. The guitar work and vocals are strong and there is very little padding added in terms of harmonies or extra instruments. It has a certain Bee Gees sound, whether it's the higher than usual pitch or not.
Benson has only 10 tracks on this record, with "Reason for Breathing" starting off okay but failing miserably the further it goes. "I think I might be going down", a lyric goes, which hits the nail on the head in terms of the track's quality. "Missing You" has more of a jazz touch, which Benson seems to lap up quickly. Although the album has a few quality tracks, the title is a bit deceiving.
Derek Hoke "Destination Unknown" (audio) (premiere) // Music
Bette Smith "I Found Love" (audio) (premiere) // Music
The Sounds of Ghosts "Train to Nowhere" (audio) (premiere) // Music
Late Night Episode "Golden Age (Acoustic)" (video) (premiere) // Music
Dan Miraldi 'Love Under Fire' (audio) (premiere) // Music
Sci-Fi Author Ursula LeGuin's Stories of Class War, Religious Dissension, Identity Politics and More
20 Questions: Amadou & Miriam
// Sound Affects
"For their ninth studio album, acclaimed Malian duo Amadou & Miriam integrate synths into their sound while displaying an overt love of Pink Floyd.READ the article


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Stephen Antonakos (1926-2013)
Stephen Antonakos, a pioneer in neon art, died in New York City on August 19. He was 87. The Greek native's 1993 piece, "Neon for Stadtsparkasse, Cologne, Germany," appeared on the cover of Christiann Schiess' 1994 book entitled, "The Light Artist Anthology," which was the first book to broadly capture the realm of neon art. Schiess had interviewed Antonakos for the February 1987 issue of Signs of the Times magazine.
Antonakos, whose family immigrated to the U.S. (New York City) in 1930, first began experimenting with neon in the 1950s. Perhaps his earliest piece to appear in print was from 1962, entitled "White Light." Antonakos didn't physically bend the neon for his creations: "I don't involve myelf with some of the other technicalities because, I decided years ago to limit myself to the aesthetics of neon," he said in his interview with Schiess.
Antonakos has permanent installations in Japan, Greece, Germany, Los Angeles, Chicago, and Boston, as well as New York. Overall, he had more than 100 one-person shows and participated in more than 250 group shows. Much of his work was also publicly funded outdoor creations, such as "The Room" in Grand Rapids, MI (1973) , "Incomplete Neon Square" in West Germany (1977) and "Neon for 42nd St. in New York (1979).
Much more can be seen at his official website, http://www.stephenantonakos.com/.


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James Perse returns with a new ping pong table. Their first (featured on Selectism back in Jul 2009) was a simple affair with all the necessary treatments to make it official. Their new limited edition ping pong table steps it up a notch with wood teak framing. "Following the same principles and design aesthetic of the James Perse Furniture Collection, the James Perse Limited Edition Ping Pong Table is hand-crafted from environmentally farmed solid teak. It combines playability with functionality – remove the net and cover with the optional teak table top to convert the game room into a dining or conference room." Comes with custom paddles as well.
More looks after the click.


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Tuesday, September 19, 2017
Smoking and Tobacco
Black and Milds
What does black and mild contains inside of it?
Black & Milds are pipe-tobacco cigars, look like mini cigars, and are filled with 100% pipe tobacco. The Surgeon General Warning that appears on the front of the package of 5 reads: "Cigars Are Not A Safe Alternative To Cigarettes." Cigars contain nicotine, and are addictive. How much nicotine someone actually gets depends not only on how much they smoke, but also how they smoke (how frequent and deep are their puffs).
The package also reads: "These Cigars Are Predominantly Natural Tobacco With Non-Tobacco Ingredients Added", whatever that means. You would have to contact the producers of the product to find out the actual content, as it is not listed on the package:
John Middleton, Inc.
King of Prussia, PA 19406 U.S.A.
Good websites to refer to are the American Cancer Society:
www.cancer.org (search for cigars)
Surgeon General:
www.surgeongeneral.gov/tobacco (search for The Health Consequences of Smoking: a Report of the Surgeon General (5/27/2004); then search for the interactive animation, "The Health Consequences of Smoking on the Body.")
Kathy Vesha, RN, BSN, MA
Kick It!
The James
The Ohio State University


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Comparison Of Morning And Evening Dosing Of Valsartan And Lisinopril In Patients With Diabetes
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: October 14, 2005
Last updated: November 22, 2011
Last verified: November 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
A study comparing the antihypertensives Valsartan and Lisinporil when doses are in the morning and comparing a morning dose of Valsartan with an evening dose.
|Drug: valsartan Drug: lisinopril
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
|Official Title:
|A Randomized, Double Blind, Double Dummy, Parallel Group, Active-Controlled Study To Evaluate The Effectiveness Of Morning Versus Evening Doses Of 320 Mg Valsartan Versus 40 Mg Lisinopril On The 24 Hour Blood Pressure Profile In Patients With Hypertension And Non-Insulin Dependent Diabetes
Resource links provided by NLM:
Drug Information available for: Lisinopril ValsartanU.S. FDA Resources
Further study details as provided by Novartis:
Primary Outcome Measures:
- Average 24 hour blood pressure less than 130/80 mmHg after 26 weeks
- Change from baseline in systolic 24 hour blood pressure after 12 weeks
Secondary Outcome Measures:
- Change from baseline manual blood pressure and pulse pressure after 26 weeks
- Change from baseline markers of endothelial function, fibrosis, and other blood measurements of hypertension after 12 and 26 weeks
- Changes in ambulatory blood pressure measurements at various timepoints up to 26 weeks
- Change from baseline heart size after 26 weeks
- Adverse events, serious adverse events, laboratory values, physical examinations, vital signs for up to 26 weeks
|Study Start Date:
|April 2004
|Study Completion Date:
|June 2005
|Primary Completion Date:
|June 2005 (Final data collection date for primary outcome measure)
|Ages Eligible for Study:
|65 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Hypertension defined by a MSSBP >=150 mmHg (untreated patients) or patients on current anti-hypertensive treatment who remain uncontrolled (i.e. MSSBP >140 mmHg)
- Randomisation mean 24h blood pressure above 130/80 mmHg
- In addition the patients must fulfill, at least, one of the following criteria:
Controlled type II Diabetes mellitus Hypercholesteremia, currently treated with lipid-lowering drugs Metabolic syndrome MI, CABG or PTCA more than one year ago Stroke or transient ischemic cerebral attack more than one year ago Documented history of peripheral vascular disease, increased IMT, or carotid plaques Documented history of LVH Elderly >65 years
Exclusion Criteria:
- - MSSBP >=180 mmHg and/or MSDBP >= 110 mmHg at any time from Visit 1 to Visit 3
- Inability to discontinue all prior anti-hypertensive medications safely for a period of three weeks
- Mandatory indication for any concomitant medication for coronary artery disease or any other disease that is not allowed during this study.
Other protocol-defined exclusion criteria may apply.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00241124
Please refer to this study by its ClinicalTrials.gov identifier: NCT00241124
|Investigative Centers, Germany
Sponsors and Collaborators
|Study Director:
|Novartis Pharmaceuticals
|Novartis Pharmaceuticals
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Novartis:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT00241124 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 14, 2005
|Last Updated:
|November 22, 2011
Keywords provided by Novartis:
morning/evening dosing
Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases
Antihypertensive Agents
Angiotensin II Type 1 Receptor Blockers
Angiotensin Receptor Antagonists
Molecular Mechanisms of Pharmacological Action
Angiotensin-Converting Enzyme Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Cardiotonic Agents
Protective Agents
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


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Indian firms raise Rs 2.81 lakh cr in Apr-Dec 2012: Survey
Indian companies raised a total of Rs 2.81 lakh crore in fresh capital from equity and debt markets in the April-December period of 2012.india Updated: Feb 27, 2013 15:11 IST
Indian companies raised a total of Rs 2.81 lakh crore in fresh capital from equity and debt markets in the April-December period of 2012.
According to the Economic Survey for 2012-13, the pre-Budget annual report card on the state of the economy, the funds raised by Indian companies in the first nine months of the current fiscal at Rs 2,81,667 crore, was below Rs 3,09,750 crore raised in the entire fiscal year 2011-12.
In 2010-11, Indian firms raised a total of Rs 2.76 lakh crore, while Rs 2.61 lakh crore were mopped up during 2009-10.
During the April-December period of current fiscal, funds were raised through debt, equity including Initial Public Offers (IPOs) and private placement of debt and equity.
There were no activity in the area of fund-raising through American Depository Receipts (ADR) and Global Depository Receipts (GDR) issues during the period, the Survey said.
A total of about Rs 13,050 crore has been garnered from the equity market during the period under review, which is higher than Rs 12,857 crore raised during 2011-12.
However, there were only 20 IPOs in April-December period of 2012 and the funds raised through public issues totalled about Rs 6,043 crore.
In the fiscal 2011-12, 34 firms garnered about Rs 5,904 crore.
The average size of initial share sale offers by Indian companies rose to Rs 302 crore in April-December period of 2012, as against to Rs 174 crore in previous fiscal.
The amount of capital mobilised through private placement was at Rs 2.63 lakh crore as compared to Rs 2.61 lakh crore in 2011-12.
Further, about Rs 4,974 crore was raked in through public issues in debt category as against Rs 35,611 crore in 2011-12.


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"Hi Sonya! My name is Megan and I live in Nashville. I read ur profile and seems like we might have also of fun playing. Let me know wht u think. I'm dieing to get back on the court :)"
24 members16 Comments 4 Likes
Sonya Stanley has not received any gifts yet
Searching for hitting partners. Live in Spring Hill, but will travel. Am a pretty good rec player. Please respond if interested
© 2017 Created by Mark / The Mayor. Powered by


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Mommy's Little PeanutThat's what I used to call my son. The happiest day of my life was when he was born. I do have other children who I love so much but the first one just because of the whole new experience is well just different. He used to look at me like I was a God or something, he would just make me melt.He loved me so much. I couldn't wait to wake up to see his beautiful little face and spend every second of the day with him. I love him so much. He is now a grown young man, not married yet but somehow he changed. We talk but my heart breaks I don't know why he is so distant. I almost feel like he is resentful or something, I wish I knew. His Dad and I are still married but it's not a good marriage. I think that might have something to do with it. I feel guilty that maybe I should have left his Dad years ago instead of staying in a marriage that was broken. I thought I was doing the right thing but maybe not. I have talked to my son about it but got nowhere. Just remember these precious little children see things and hear everything. It can do harm to them. I'll probably always have that guilt whether it's from the marriage or not because I could have made a difference, I should have left. My husband would say go ahead leave you'll end up in a trailer somewhere, with nothing.Always make me feel that I couldn't leave. I was so stupid. Now we are probably going to separate. The kids are all grown, not really what I thought would happen after given him the best years of my life. I always put everyone before myself, was a stay at home Mom, cooked like crazy, baked, cleaned, took care of parents, gave the kids the best life I could...but would it have been better if I would have left?
Sorry for my bad English at first.

When we were expected our first kid I sed to my wife's doctor what is it (boy-or girl ) and he told me 99 /100 is a girl .then I told him thanks that you give me at least 1/100 changes . After 4 years finally a miracle was happen . My wife again pregned and when I hearted from the doctor the goog news I was flying .we say good health to have the kid and girl or boy no mater but my son is remin my myself .thanks
Hunny,

My heart aches for you. Sigh.

Having your son view you in such an uncaring way is devastating. Don't give up on your relationship with him. You should go out on a "date" with him, have some cocktails and confess your feelings. Trust me, he'll open up completely.

Let the healing start.

No point wondering what if. AND.....the best years of your life can be the next 25, if you let them.

I know what you mean about the love you have for kids. I never really understood the meaning of love, until they put my first baby into my arms, the first time. I suddenly knew that I had never known what it meant to love with every fiber of my being, before. As much as I loved my parents and my husband, it paled by comparison. I was in total awe of this tiny being.


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The National Highway Traffic Safety Administration said it has opened an investigation into two popular Honda models, the 2003-2004 Honda Pilot sport utility vehicles and 2003-2004 Honda Odyssey minivans. The federal safety agency has received numerous complaints of the vehicles rolling away after consumers reportedly parked the vehicles and removed the keys.
According to the NHTSA's Office of Defect Investigations, there have been more than 40 complaints of Honda Pilots and Odysseys rolling away. In one consumer report, a driver hurt her knee trying to stop her vehicle as it rolled. In another incident, a driver received a broken leg while attempting to stop their 2003 Honda Odyssey from rolling away.
Engineers with the ODI and Honda will investigate if there is an issue with the transmission interlocks found in the Honda minivans and SUVs, which are suppose to prevent ignition key removal unless the automatic transmission are engaged in the "Park" setting. An official recall notice of those vehicles—popular among consumers during the 2003-2004 model years because of their size and reported reliability—may be determined after the NHTSA and Honda complete their investigation.
In the meantime, Honda urges owners to exercise care and to use the vehicles manual parking brake.
Consumers who experience a similar roll-away situation—or any safety issue with any vehicle—should read our report on how to file a safety complaint with the NHTSA on its website: www.SaferCar.gov.
ODI Complaint: 2003-2004 Honda Pilot / Honda Odyssey - Ignition switch Action #: PE12026 [NHTSA]
US safety officials investigate Honda Pilot SUVs, Odyssey minivans that roll away unexpectedly [AP via the Washington Post]
—Paul Eng
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Resolution Run 2013 - 5K Run/Walk
Savannah Rapids Park
Sat 01/12/2013
250 Participants
Register BEFORE December 27th, 11:59pm to be guaranteed a Dri-fit T-shirt! Registration will begin at 8:00am Race will begin at 9:00am The beautiful Savannah Rapids Park in Martinez, GA will set the stage for the run/walk, which will start near the head-gates of the Augusta Canal. The race will follow the trail that lies between the Savannah River and the canal, allowing runners and walkers to take in the natural beauty for a full 3.1 miles. The race route is great for beginners and will be an "out and back" style, with runners and walkers racing along the canal and then turning back towards the Start/Finish line after 1.55 miles. Awards will be given to the top 3 male and top 3 female finishers. The overall male winner and overall female winner will take home a special prize! Complementary refreshments await all finishers! The inaugural race welcomed participants with icy cold weather last year and this race day is expected to be just as chilly - what better way to warm up the body than with a quick 5K alongside a few hundred friends? Come run with us! Get your New Year's resolutions off to a good start and support a great cause - Christ Church Health Clinic and the GHSU PA Class of 2014. Sign up today!
- Address:3300 Evans-to-Locks Road
Martinez, GA 30907


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Home :: Sport
Read the original news
VietNam News English
- 101 month(s) ago
4 readings
You call this lunch?
Malaysian weightlifters have complained about their meagre lunch of white rice and half a boiled egg at the SEA Games in Vientiane, Laos. "How can we pump iron by eating only this," they lamented. Athletes at the venue were unable to return to the Games Village for lunch and had to settle for a simple meal provided by the Malaysian Weightlifting Association.
Halal cafes cash in
Halal restaurant owners in Vientiane are seeing an increase in profits because of the participation of Muslim athletes and officials from several Asian countries in the Games.
Khamdeng, a restaurant employee established by a Muslim Indian in 1990, said he had received twice as many visitors as usual. "Every day we have up to 150 diners, but during the Games we have had up to 400," Khamdeng said on Saturday.
Indonesian family takes aim
The Indonesian shooting team at the 25th SEA Games boasts three siblings: Rachma Saraswati, and her brothers Rahmat Wisnu Aji and Agus Anindito. "They share my interest in shooting," Kuncung Sudiono, an Indonesian shooting coach and father of three, told Antara on Saturday. He said the Games were the first for his children and he hoped they would gain experience for the next Games hosted by Indonesia.
Sudiono said Rahmat and Agus had participated in the sport for a long time and had represented South Sumatra since the 2004 National Games in Palembang. Saraswati represented South Sumatra in the 2007 National Games.
"It s a new experience for her, but she is good," he said, citing the silver medal Saraswati, Erlinawati and Maharani Ardi won for the 50mrifle prone women s team. Erlinawati won the individual prone 50m rifle contest.
Indonesian journalist dies
Lukmanul Hakim died on Friday while reporting for Republika Daily during the Southeast Asian Games taking place in Laos. Lukman, 40, was found collapsed on top of his papers when writing for his paper at an internet kiosk about 5 pm local time. His body was rushed to Mittaphap hospital where he died on arrival. Born in Semarang in Central Java, Lukman had complained about heart problems before leaving for Laos.
Thai journalists look for work
Many Thai journalists who cover football are struggling to find something to do in Vientiane after Thailand were sent packing. Many of them are focusing on women s football or covering other sports such as diving and petanque. Thailand s national Under-23 team was unexpectedly ousted from the group stage after their 1-2 defeat by Malaysia last Friday. Agencies/VNS
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text:
- Score:
- rated 4.40 / 5 stars
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- Genre:
- Comedy - Original
- animals
- siblings
- spike
- dogs
Credits & Info
- Uploaded
- Apr 17, 2007 | 3:11 PM EDT
- Frontpaged April 18, 2007
- Daily 5th Place April 18, 2007
If you liked this, check these out!
Plenty more like this here!
Author Comments
Rated 5 / 5 stars
My roomies dog always gives me weird looks when I play WoW. You captured that perfectly! I'd like to see more!
Oh you will see more in due time, Worlo. Thanks for the comment!
Rated 5 / 5 stars
they just keep getting better!
iv been watching like every video you've made and they just keep getting better! your art style is awesome and your jokes are actually funny! cant say that about too many people any more. keep up the great work!
Rated 5 / 5 stars
hi spike!
lolz im addicted to this movie one of my favroties!
Rated 5 / 5 stars
I would quote the most hilarious parts of this episode, but I'd have to copy out the entire script. Even though I just watched, rated and reviewed episode 2, saying that it was the best you've done, after seeing this, I've changed my mind. I didn't stop laughing through this entire movie! I really don't know what else to say...
What the hell, since this movie was so perfect, I'm gonna have to give you all 10s, and rate it a 5, just for the sake of it.
Rated 5 / 5 stars
ficken hilarius
lolololol tht was super funny and good animation!
i love it so much!
Thank you so much!


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Type to Search
Just make sure the kids are asleep before you two have a romantic, sexy, and sometimes even naughty evening!
Top 10 Reasons Guys Love the Holidays
Just make sure the kids are asleep!
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LOS ANGELES (Jul. 24)
Max Gabel, prominent Yiddish actor and playwright, who wrote about 120 plays, has died here. He was 75 years old. Funeral services will take place tomorrow.
Born in Gorlitz, Galicia, he was brought to the United States at the age of 11, and while working in factories he was attracted to the Yiddish theatre. At the age of 14 he joined a dramatic club in New York and later became one of the leading stars of the Jewish stage. He retired in 1932 and settled in California.


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A raccoon that attacked a 17-month-old boy and his father in the Country Club Lane area on Aug. 11 tested positive for rabies over the weekend, the first case this year for Galax, said Kristina Webb, an environmental health specialist at the city's health department.
The child and his father have received their second of six sets of treatments. Both were treated for rabies the day of the attack at the emergency room at Twin County Regional Hospital, while they awaited lab results.
HILLSVILLE — Carroll County Circuit Court personnel are credited with saving the life of a well-known defense attorney who suffered a sudden health issue Thursday afternoon.
DRAPER –– Galax golf coach Terry Snow probably got a pretty good idea of how stout his team could be after a scrimmage last week netted a team score of 1-under par.
Monday's events have only fueled his optimism.
The Maroon Tide turned in a solid four-man team score of 295 to win the Draper Valley Prep Classic, a 15-team season-opening event held at the 6,414-yard par-72 Draper Valley Golf Club.
Clark Williams has got to be a pretty sharp fellow.
An ordinary dullard doesn't make it through college and into the financial world as a commercial account executive with the nation's largest banking company, and a common dolt doesn't drop that career and successfully navigate his way through the rigors of physical therapy school.
(Note: A correction was made from the print version of this story. Due to a version of a schedule that was incorrect, Grayson County's scrimmage at Eastern Motgomery should have been stated as 10 a.m. on Saturday.)
All three Twin County high school football teams will see how the last two weeks of practices have paid off as scrimmage time finally arrives this weekend for Galax, Grayson County and Carroll County.
Galax will get into action today (Friday), hosting Giles in its first scrimmage this afternoon at 5 p.m.
HILLSVILLE — Utility projects in Fancy Gap still await the approval of Rural Development before going to bid.
The Carroll County Public Service Authority members received an update on the status of the Fancy Gap water and sewer projects at their regular August meeting Monday.
Paperwork in their board packet noted that the water portion awaits final authorization from the U.S. Department of Agriculture to advertise for construction bids.
By TINA E. VAUGHN
INDEPENDENCE — In a surprise move, Grayson County Board of Supervisors' Vice Chairman Doug Carrico said Wednesday morning that he will not seek re-election as the board's at-large member.
Carrico, now serving his second term, announced last week that he would run as a political independent after losing the Republican nomination to David Sexton during a mass meeting in July.
Copyright © 2017
The Galax Gazette is your source for local news, sports, events and information in Galax, Grayson, Carroll, and surrounding areas.


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Elementary students at the West Penn Elementary School, Tamaqua Area School District, were treated to intereactive programs to help them understand and learn about fire prevention, safety and protection.
Members of the West Penn Fire Company and fire police volunteered their time to hold the programs for the students.
West Penn Fire Company Fire Chief Clint Schock started off each session talking to students about how to react during a fire.
Afterwards, students were given chance to go through a simulation house, as well as view the company's fire apparatus.


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Sat 16th Feb at 8:00pm
Bluestocking Lounge's Love-In
@ Swansea Grand Theatre and Arts Wing, Swansea
Featuring: Miss Dolly Rose, Flixx Demontrant, Atheria Hart, Lilly Laudanum, Boris And Doris Von Sneeze, Lola La Rouge, DeeDee DeLa Rouge
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Bluestocking Lounge's Love-In: Miss Dolly Rose, Flixx Demontrant, Atheria Hart, Lilly Laudanum, Boris And Doris Von Sneeze, Lola La Rouge, DeeDee DeLa Rouge
"A glittering night full of eclectic and alternative burlesque and cabaret. February sees the return by popular demand of boylesque artist Flixx Demontrant and headliner Dolly Rose. Special prize for the best dressed audience member.
Info provided by the Event Organiser
Miss Dolly Rose
A petite platinum blonde with a passion for vintage dance styles and music, Miss Dolly Rose performs burlesque inspired by the sweethearts and sirens of early Hollywood, recreating the allure of silver screen starlets and good time dancing girls.
Miss Dolly Rose tour dates
Flixx Demontrant
An artist with a knack for clever characters and comedic timing, he is also known as the 'Johnny Depp of burlesque'.
Flixx Demontrant tour dates
Atheria Hart
'... the Hart of British burlesque...' Trained in dance from the age of three, her skills in fine art combine transport audiences into a magical world where anything is possible.
Atheria Hart tour dates
Lilly Laudanum
Lilly Laudanum is a burlesque performer whose gory stories and playful parodies are anything but routine.
Lilly Laudanum tour dates
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Venue Facts
Venue: Swansea Grand Theatre and Arts Wing
Website: swanseagrand.co.uk
Bookings: 01792 475715
Disabled Bookings: 01792 475715
Seating Plan: View the Seating Plan
→ Swansea 12 min walk
→ Swansea Docks 12 min walk


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Research Topics
Jonathan I Flombaum
Affiliation: Yale University
Country: USA
Research Grants
Detail Information
- A temporal same-object advantage in the tunnel effect: facilitated change detection for persisting objectsJonathan I Flombaum
Department of Psychology, Yale University, New Haven, CT 06520 8205, USA
J Exp Psychol Hum Percept Perform 32:840-53. 2006..This suggests that persisting objects are the underlying units of visual memory...
- Dynamic object individuation in rhesus macaques: a study of the tunnel effectJonathan I Flombaum
Department of Psychology, Yale University, New Haven, CT 06520, USA
Psychol Sci 15:795-800. 2004..With further control conditions, this experiment demonstrates a spatiotemporal bias-similar to a bias found in adult visual perception-in the computation of object persistence in the context of a dynamic correspondence problem...
- Rhesus monkeys attribute perceptions to othersJonathan I Flombaum
Department of Psychology, Yale University, New Haven, CT 06520, USA
Curr Biol 15:447-52. 2005..Moreover, they raise the possibility that, in primates, cortical cells thought to encode where others are looking [7] may encode what those individuals see as well...
- Rhesus monkeys (Macaca mulatta) spontaneously compute addition operations over large numbersJonathan I Flombaum
Department of Psychology, Yale University, Box 208205, New Haven, CT 06520 8205, USA
Cognition 97:315-25. 2005....
- Attentional resources in visual tracking through occlusion: the high-beams effectJonathan I Flombaum
Department of Psychology, Yale University, Box 208205, New Haven, CT 06520 8205, USA
Cognition 107:904-31. 2008..This new attentional high-beams effect indicates that the ability to track through occlusion, though seemingly effortless, in fact requires the active allocation of special attentional resources...
- Cognitive and brain consequences of conflictJin Fan
Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, New York, 10021, USA
Neuroimage 18:42-57. 2003....
- The activation of attentional networksJin Fan
Laboratory of Neuroimaging, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Neuroimage 26:471-9. 2005..Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention...
- Spatiotemporal object continuity in human ventral visual cortexDo Joon Yi
Department of Psychology, Yonsei University, Seoul 120 749, Korea
Proc Natl Acad Sci U S A 105:8840-5. 2008..These results indicate that spatiotemporal continuity modulates neural representations of object identity, influencing judgments of object persistence even in the most staunchly "featural" areas of ventral visual cortex...
Research Grants1
- Persisting Objects and the Nature of Attention and MemoryJONATHAN FLOMBAUM; Fiscal Year: 2007..g. air-traffic control). [unreadable] [unreadable] [unreadable]..


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Exhibitor Services
ISE is proud of its reputation of providing a 'gold card' service to its exhibitors, from the moment they sign up right through to break down on the last day of the show. Some of these exclusive services include:
Provision of personalised ISE invitation cards with a free exhibitor invitation code – just give us your order and we send you the personalised cards to invite your customers.
Free use of the ISE exhibitor/sponsor icon – this can be used on all marketing collateral for exhibitors to promote the show in print and online.
Access to Exhibitor 'back office' to upload press releases, use meeting maker and manage sponsorships.
The ability to sign up to the ISE M2D tool to allow exhibitors to search and locate potential international distributors.
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For logistics and stand builders please see our list of official suppliers page:
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Our Show Floor Theatres offer a special opportunity for all exhibitors to present an educational session to a relevant audience. The theatres are categorised into five market segments – Residential Solutions, Commercial Solutions, Unified Communications, Audio Solutions and Smart Buildings Solutions. Exhibitors can pitch presentations that focus on market insights, case studies and project stories. There is no additional charge for this. The aim is to provide a platform for exhibitors to share industry knowledge. It isn't a platform for simply promoting a company or its products.


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Because he has set his love upon Me, therefore I will deliver him; I will set him on high, because he has known My name. He shall call upon Me, and I will answer him; I will be with him in trouble; I will deliver him and honor him,' Psalm 91:14-15
Painting With Light Detail-
Call Upon Me Psalm 91:14-15. Painting With Light II. Mixed media on canvas. Copyright 2009 by Mark Lawrence. All Rights Reserved.
* Painting With LightThis painting has been rendered with a unique Painting with Light technique that paints the picture using the selected Bible verse text as the paintbrush. You are seeing the verse above painted imperceptibly millions of times repeatedly across the canvas!
Enjoy Mark Lawrences biblically inspired modern sacred art, translated into large and colorful canvases in his unique abstract-expressionist contemporary artwork style.
This art is available as a Limited Collectors Edition Fine Art Giclee, ultra-hand embellished, hand-signed and numbered by Mark Lawrence. Collectors Editions are limited to 100 and are available at MarkLawrenceGallery.com.
Contact email@example.com if we can assist you in any way with your Mark Lawrence acquisition.
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Here at Reactions, we ask the tough questions to get to the bottom of the biggest scientific quandaries.
In that spirit, this week's video explains why dogs sniff each other's butts.
It's a somewhat silly question with a surprisingly complex answer.
This behavior is just one of many interesting forms of chemical communication in the animal kingdom.


text: su, 2009-12-06 kello 23:01 -0800, Fernando Perez kirjoitti: > 2009/12/6 josef.pktd <email@example.com>: > >>>> np.equal(np.arange(5),'a') > > NotImplemented > > Why is NotImplemented a *return* value? Normally NotImplementedError > is a raised exception, but if it's not implemented, it shouldn't be > returned as a value. Maybe it is so because some code paths are shared with the == operation? But in any case, NotImplemented should never be returned to the user -- I believe it's only meant to be an internal value used in determining the proper comparison operation between values. A bug ticket should be filed for this, I believe. -- Pauli Virtanen


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Now that Christmas Day is over -- and Jessicayla wants me to emphasize that the Christmas Challenge is still open till December 31st -- we have a week before chitkaran introduces Challenge 7 and a special holiday coming up, the New Year.
The Challenge Winner will be decided by a PSG Celebrity Alumnus and Awesome Guru, Mark the Keeper.
Judging will be done on New Year's Day. The winner will receive the PSG Medal of Honor, and will be asked to do the next holiday challenge, Valentine's Day, or not to be US-centric, maybe your country has a holiday you observe that you would like to honor. It's up to the winner to accept that "prize!" It will of course be separate from the numbered challenges and the winner will be able to do the following holiday if he/she wants it.
This week alongside the postcard theme, the new challenge is to make something which says Happy New Year to you.
It can be typography with a message, even a poem. It can be a manipulation demonstrating your feelings about the year to come or the year past. It could be a collage or image of your New Year's Intentions or frustration over intentions, lol. Anything. Use your imagination and create from the heart.
Have fun in Photoshop and use your favorite tools, imagery, and skills!. That's all you need to do.


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10 Spine-Friendly Yoga Poses for Better Posture
It's tougher than ever for celebrities to live and age under the scrutiny of public pressure, if their continual body-shaming is any evidence. And while some claim to eat cheeseburgers and work out whenever they feel like it, others are taking...unconventional means to trim their waists. Japanese potatoes? Baby food? Whiskey? Ahead, some of the strangest fad diets and anti-aging hacks stars have ever tried.More
We're big fans of essential oils for their healing benefits, but according to the Blackbook of Celebrity Diet Secrets, stars like J.Lo take it one step further by seeking out grapefruit essence to lose weight.
The multi-hyphenate singer/actress/producer regularly takes whiffs from a vial of the fruit-based oil, which some believe affects the liver enzymes and promotes weight loss.
Another tidbit from the Blackbook of Celebrity Diet Secrets and the Epsom Salt spokesman himself is that supermodel Heidi Klum looks to epsom salts to keep her as trim as possible on the red carpet. She apparently soaks in a bath full of them before events in order to reduce bloating and draw out excess fluids.
The naturally occurring mineral is also purported to ease migraines, improve sleep, and flush toxins from the body—for what its worth—according to the Epsom Salt Industry Council.
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