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Samarium 153 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Radioactive substances, such as samarium 153, may release radiation as it breaks down and kill cancer cells. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Bortezomib may also make tumor cells more sensitive to radiation. Giving samarium 153 together with bortezomib may kill more cancer cells.
PURPOSE: This phase I trial is studying the side effects and best dose of samarium 153 when given together with bortezomib in treating patients with relapsed or refractory multiple myeloma.
|Multiple Myeloma and Plasma Cell Neoplasm
|Drug: bortezomib Radiation: samarium Sm 153 lexidronam pentasodium
|Phase 1
|Study Type:
|Study Design:
|Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|A Phase I Study of Samarium Sm-153 Lexidronam Combined With Bortezomib for Patients With Relapsed or Refractory Multiple Myeloma
- Maximum tolerated dose and dose-limiting toxicity
- Response rate (complete, partial, and minimal response)
- Time to disease progression and time to response
- Progression-free and overall survival
- Antitumor effects
|Estimated Enrollment:
|Study Start Date:
|December 2005
|Study Completion Date:
|February 2011
|Primary Completion Date:
|June 2008 (Final data collection date for primary outcome measure)
- Assess the safety and tolerability (maximum tolerated dose and dose-limiting toxicity) of samarium Sm 153 lexidronam pentasodium and bortezomib in patients with relapsed or refractory multiple myeloma.
- Determine the response rate (combined complete response, partial response, and minimal response) in patients treated with this regimen.
- Determine the time to response and the time to progression of disease in patients treated with this regimen.
- Determine the progression-free survival and overall survival of patients treated with this regimen.
- Assess the antitumor effects of this regimen in these patients.
OUTLINE: This is an open-label, dose-escalation study of samarium Sm 153 lexidronam pentasodium.
Patients receive bortezomib IV over 3-5 seconds on days 1, 4, 8, and 11 and samarium Sm 153 lexidronam pentasodium IV on day 3. Treatment repeats every 8 weeks for up to 4 courses in the absence of disease progression or unacceptable toxicity.
Cohorts of 3-6 patients receive escalating doses of samarium Sm 153 lexidronam pentasodium until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose preceding that at which 2 of 6 patients experience dose-limiting toxicity. The MTD of samarium Sm 153 lexidronam pentasodium is determined with 2 different doses of bortezomib.
After completion of study treatment, patients are followed every 3 months.
PROJECTED ACCRUAL: A total of 36 patients will be accrued for this study.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Diagnosed with multiple myeloma by 1 of the following criteria:
Meets any 2 of the following major criteria:
- Plasmacytomas on tissue biopsy
- Bone marrow plasmacytosis (i.e., > 30% plasma cells)
- Monoclonal immunoglobulin spike IgG > 3.5 g/dL or IgA > 2.0 g/dL by serum electrophoresis; kappa or lambda light chain excretion > 1 g by 24-hour urine protein electrophoresis
Plasmacytomas on tissue biopsy AND meets any 1 of the following minor criteria:
- Presence of monoclonal immunoglobulin at a lesser magnitude than given under above major criteria
- Lytic bone lesions
- Normal IgM < 50 mg/dL, IgA < 100 mg/dL, or IgG < 600 mg/dL
Monoclonal immunoglobulin spike IgG > 3.5 g/dL or IgA > 2.0 g/dL by serum electrophoresis; kappa or lambda light chain excretion > 1 g by 24-hour urine protein electrophoresis AND meets 1 of the following minor criteria:
- Bone marrow plasmacytosis (i.e., 10-30% plasma cells)
- Lytic bone lesions
Presence of monoclonal immunoglobulin at a lesser magnitude than given under major criteria with bone marrow plasmacytosis (i.e., 10-30% plasma cells) AND meets 1 of the following minor criteria:
- Lytic bone lesions
- Normal IgM < 50 mg/dL, IgA < 100 mg/dL, or IgG < 600 mg/dL
- Measurable disease, defined as a monoclonal immunoglobulin spike of ≥ 1 gm/dL by serum electrophoresis and/or a immunoglobulin spike of ≥ 200 mg by 24-hour urine protein electrophoresis or evidence of lytic bone disease OR
- Nonmeasurable disease (i.e., patients with nonsecretory or oligosecretory multiple myeloma)
Relapsed or refractory disease
- Relapsed disease following a response or stable disease after prior chemotherapy (e.g., single-agent steroids, vincristine, doxorubicin, and dexamethasone [VAD], or melphalan and prednisone [MP]) or high-dose chemotherapy
- Refractory (i.e., failure to achieve at least complete or partial response or stable disease) to the most recent chemotherapy with or without systemic corticosteroids
- No plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, monoclonal protein (M-protein), and skin changes (POEMS syndrome)
- No extramedullary myeloma
- Karnofsky performance status 60-100%
- Life expectancy > 3 months
- Absolute neutrophil count ≥ 1,500/mm³
- Platelet count ≥ 75,000/mm³
- AST and ALT ≤ 3 times upper limit of normal (ULN)
- Bilirubin ≤ 2 times ULN (unless clearly related to disease)
Creatinine clearance ≥ 30 mL/min
- Creatinine clearance > 15 mL/min and < 30 mL/min due to significant myelomatous involvement of kidneys allowed at discretion of investigator
- Sodium > 130 mmol/L
- No ECG evidence of acute ischemia or new conduction system abnormalities
- No myocardial infarction within the past 6 months
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception
- No active infection
- No severe hypercalcemia (i.e., serum calcium ≥ 14 mg/dL)
- No New York Hospital Association class III or IV heart failure
- No poorly controlled hypertension, diabetes mellitus, or other serious medical or psychiatric illness that would preclude study treatment
- No known HIV history
- No known active hepatitis B or C viral infection
- No history of allergic reaction attributable to compounds of similar chemical or biological composition to bortezomib, boron, mannitol, ethylenediaminetetramethylenephosphonic acid (EDTMP), or phosphonates
- No peripheral neuropathy > grade 1
At least 12 weeks since prior samarium Sm 153 lexidronam pentasodium
- No more than 1 prior treatment
At least 24 weeks since prior strontium chloride Sr 89
- No more than 1 prior treatment
- No major surgery within the past 4 weeks
- No chemotherapy within the past 3 weeks (6 weeks for nitrosoureas)
- No corticosteroids (> 10 mg/day prednisone or equivalent) within the past 3 weeks
- No immunotherapy, antibody therapy, or radiotherapy (except localized radiotherapy) within the past 4 weeks
- No other concurrent investigational agents
- No concurrent corticosteroids (≥ 10 mg prednisone or equivalent)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00316940
|United States, California
|Comprehensive Blood and Cancer Center
|Bakersfield, California, United States, 93309-0633
|Hematology-Oncology Medical Group of Fresno, Incorporated
|Fresno, California, United States, 93720
|West Hollywood, California, United States, 90069
|United States, Maryland
|Center for Cancer and Blood Disorders at Suburban Hospital
|Bethesda, Maryland, United States, 20817
|Principal Investigator:
|James R. Berenson, MD
|ClinicalTrials.gov Identifier:
|NCT00316940 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 19, 2006
|Last Updated:
|September 19, 2013
Keywords provided by National Cancer Institute (NCI):
stage I multiple myeloma
stage II multiple myeloma
stage III multiple myeloma
refractory multiple myeloma
Additional relevant MeSH terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Neoplasms by Histologic Type
Hemostatic Disorders
Vascular Diseases
Cardiovascular Diseases
Blood Protein Disorders
Hematologic Diseases
Hemorrhagic Disorders
Lymphoproliferative Disorders
Immunoproliferative Disorders
Immune System Diseases
Samarium ethylenediaminetetramethylenephosphonate
Antineoplastic Agents
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on August 23, 2017


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(CBS News) -- CBS News political director John Dickerson was joined on Hotsheet Live Friday by National Journal's Reid Wilson, PBS's Christina Bellantoni, and The New York Time's Michael Shear to discuss the April jobs report.
The Labor Department said the economy added just 115,000 new jobs last month, though the unemployment rate fell slightly to 8.1 percent as some workers gave up on their job search and are not counted in the unemployment statistics.
"We are at the point, traditionally speaking, at which people's opinions about the economy generally harden," said Wilson. "Here we are six months out, the way people feel about the economy now is probably going to look very similar to the way that people will feel about the economy on Election Day."
And the president will have an especially tough selling in states like Virginia and Ohio, Dickerson said.
"President Obama has another few months to get people to start feeling better about the economy," Bellantoni added.
Each guest concluded the show by sharing their endorsements for the week.
Michael Shear endorsed David Maraniss's new book "Barack Obama: The Story," as well as the new movie Avengers.
Christina Bellantoni shared a slogan she learned during a recent vacation. "The Costa Rican slogan on a keychain I have right here is 'pura vida,' which literally means 'good life,'" she said. "I thought I want to take that back with me to Washington because I think we all lose that sometimes."
Reid Wilson endorsed Joshua Green's column today in the Boston Globe, "Zombie Congress."
And lastly, host John Dickerson endorsed Bill Clinton's review of "The Passage of Power" by Robert Caro
Watch the entire discussion, including the panelists' thoughts on the Obama campaign's "The Life of Julia," in the video above.

subset: commoncrawl


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Giving Flowers 101Submitted by SharpMan Editorial Team on Tuesday 12th October 2010
- Choosing flowers your SharpWoman will love — every time.
- Flowers and flower arrangements to avoid.
- Sending flowers to your long-distance SharpWoman.
If you've ever wondered why a virile, manly guy like yourself should ever bother to learn about something as dainty and frilly as flowers, here's your answer.
Women Love Flowers
Yup, on the scale of romantic gestures guaranteed to score you points, flowers are pretty high up there. In fact, among the SharpWomen we polled, only jewelry rated higher. (I personally prefer SharpMan Media stock options, but let's not get into that here.)
Of course, as a SharpMan, you'll want your flowers to stand out from the pack. Learn a little about how to buy a great bouquet, and it'll put you far ahead of the romantic competition. Keep reading for the SharpDating skinny on all you need to know:
Do You Have to Shell Out a Lot?
Here's the big secret: no. If your flowers say "romance" and "taste," women don't really care how little you spend. Really. Remember, it is the thought that counts. So if your thought is "You're great," "I had a nice time," "I really like/love you," "I remembered" or anything else your SharpWoman wants to hear, showing her with flowers will have no relation to the, uh, size of your bouquet.
Of course, presentation has a lot to do with how well your flowers (particularly modest arrangements) are received. A big smile, a bigger kiss and a fistful of stems hiding behind your back — go for the show and you'll get applause. Got it? Another winner is office deliveries; see below.
Even one flower can do it. In fact, a single, well-placed bud (it doesn't have to be a rose) placed on her pillow, on her computer keyboard, in her shower — wherever — can say "I love you" or even "I'm the one you want." Single blooms are also a great way to cheer up a down-in-the-dumps SharpWoman.
SharpMan Tip on Single-Flower Gifts: To maximize on the single-flower gesture, it's better to leave the bud where she will find it rather than hand it to her yourself. It just plays better that way.
Finally, there are some situations when spending more actually looks like less. For example, the SharpWoman you've just met will think you're a pushover for sending an outrageously large arrangement the day after a first date. Give her a break. She's got to have some room to move around in that cubicle. Besides, if that mammoth topiary is visible over the cube barrier wall, she'll never hear the end of it from her boss, and you'll inadvertently be the cause of her embarrassment. Women may deny this, but when it happens to them, they understand. See below for suggestions on the size of arrangements ideal for various situations:
When to Give Flowers
Anytime. Really. According to SharpWomen polled, spontaneous flowers (like any spontaneous act of affection) rank as one of the most romantic gestures out there. Women love to be pleasantly surprised by a beautiful bouquet at home and especially at the office (where they can show the arrangement off to jealous female colleagues, winning you big points). The size? Spontaneous flowers needn't be big and pricey. Since she's not expecting them, even modest arrangements and single stems will be winners.
First dates. First date flowers are controversial. Many SharpMen write to ask whether it's appropriate to show up with flowers at the door. Our take? Unless it's her first date ever, she's a divorcee going out for the first time after the breakup, or you're long-time friends who have finally gone out on a date, our position is "no." Dating is expensive enough without having to shell out for stems before the date even begins. If it turns out to be a great date, consider springing for flower delivery the following day. Otherwise, save your cash for dinner. Post-first-date flower arrangement size? Think "small and tasteful" to "medium." Why? It's just a first date, remember? No need to give her the impression that she doesn't have to dress up for you anymore.
Following especially romantic evenings. An excellent time for flowers is the morning after a particularly romantic evening or the Monday after a romantic weekend together: first sleepovers, first getaway weekends, etc. Ideally, these flowers should be delivered by a florist, not by you, to her office (but home is OK on a weekend), in order to maximize on the goodwill but give her the post-romance space we all need after a long evening or weekend with a new person. Remember that whole thing about absence making the heart grow fonder? It applies here. Post-romance flower size? Think "medium and tasteful."
Other special occasions. Flowers are also a nice gesture on birthdays, anniversaries and other special occasions (such as promotions), but they aren't required. You can replace flowers with some other nice gesture: an evening out, an evening in, a small gift, etc. The size for special occasion flowers? If you've ever wanted to spring for the bigger arrangement, break it out now. Otherwise, do what you can afford. After all, it's you she should be happy to get.
Of course, there are those women who believe that flowers are a given on birthdays and anniversaries. Gauge your SharpWoman to see if she's a stickler on this point. If so, forgoing flowers on these occasions will land you in the doghouse.
Doghouse offerings. Speaking of the doghouse, flowers are generally accepted by women as a welcome way to apologize and soothe injured feelings (but also see Apologizing 101: How to Apologize Without Giving in). If she's speaking to you, you may even want to throw in some time together, like out on the town. Doghouse flower arrangement size? That depends. What did you do?
What Kind?
The first rule: you don't have to give roses. Yes, they're lovely, and, yes, the flower people have seemingly convinced everyone that there's no other choice, but the fact is that since everyone believes this and gives them, they're a bit too predictable. It's like you followed the advice of some Web site that tells guys what women find romantic (just kidding!). Seriously, there are other flowers out there. And the truth is, most women prefer to get something more creative that looks like you put some thought into your purchase.
The second rule: Unless your SharpWoman specifically tells you she loves them, skip overplayed flowers like carnations, chrysanthemums and gypsophila (a.k.a., baby's breath). Unfortunately for these flowers, mass-produced arrangements have put them into the "last-minute effort" column.
The third rule in giving flowers is get what she likes. Snoop around or ask. Find out what types of flowers she's soft for (most women have one or two) and jot them down in your Palm Pilot (yes, you will forget the names). It doesn't matter if she sees you feverishly graffiti-ing — she'll think it's charming at the time and still love the arrangement just as much when she sees it.
She doesn't have a favorite flower? Get an arrangement in her favorite color(s). Still no luck? Then simply get something you like. That's right, you can have opinions, too. And with the help of a good florist, you'll probably end up with something pretty great.
The fourth and final rule? Go easy on the green stuff.
Arrangements with only a few flowers and an overwhelming amount of greenery and filling (like ferns and baby's breath) look cheesy.
Compare these two bouquets to see why (we're using roses to keep things simple):
See what we mean? The bouquet containing only 25 large roses and 10 spray roses is beautiful, tasteful and looks more impressive, while the bouquet of a dozen roses filled with greenery is decent, but looks empty and pale in comparison, despite the fact that it's pricier than the first! The latter is what most women will receive. We suggest you stand out from the crowd and go for less green.
A Word on Giving Roses
If your SharpWoman is a stickler for roses, consider varying the color of rose you choose. Aside from being predictable, red roses are often harder to get (and more expensive) around popular flower-giving times of the year. Why follow the herd? Roses come in a variety of cool colors, and look far more dramatic in orange or white. Consider choosing your SharpWoman's favorite.
Alternatively, choose a color that "communicates" for you. It won't surprise you to hear that the clever rose-marketing people (actually, rose enthusiasts) have assigned "meanings" to gifts of various rose colors. Choose the color that matches your message:
Red: I love you
Pink: thankfulness, joy
Yellow: friendship, jealousy
Coral: desire
White: innocence, purity, secrecy
Lavender: enchantment
Orange: fascination
A single full bloom: I still love you
SharpMan Tip: For romantic gifts, avoid dark crimson roses. These are designated for mourning.
Flowers and Arrangements to Avoid
Many SharpMen know about as much about buying flowers as SharpWomen know about men's athletic supporters. So to make things easy, here's a list of arrangements you should avoid at all costs. Learn it. Live it. Love it. And you'll never go wrong when making your selection.
- Flowers in a cup. These are for your assistant, colleague or professor.
- Flowers accompanied by a cute stuffed animal. These are for your little sister or niece's birthday and are acceptable romantically only if you are in high school.
- Arrangements that are too big (see above), particularly if sent to the office. These can be awkward to carry home and, well, sort of embarrassing. Better to spend your cash on quality and take the girl to a nice dinner.
- Flowers from the grocery store, unless your grocery store happens to have an amazing floral department (and many are springing up). If so, make sure the wrapping looks like the kind a florist would use. No go? Ask for the stems to be wrapped in white butcher paper and add a bow around the bottom, if possible. Otherwise, grocery store flowers are best saved for presents to your dinner host or for decorating your own LovePad.
The gist here is that your flower choice should be romantic and tasteful. When in doubt, ask for another SharpWoman's opinion. Don't have an info source? See Are There Advantages to Staying "Just Friends?"
The Card
So important. Skip scribbling something on that attached blank card and you risk minimizing your points-earning effort. What should you write? It depends on your reason for forking out for the buds:
For example, Anytime flower cards can simply read "I love you." Since "Thinking of you" has been overdone by flower commercials, consider "Thinking of you and that/your [insert some adorable thing she did]."
Post-first-date flower cards should be a bit more guarded. Don't give away the farm. Simply scrawl "I had a great time." We suggest adding your first name, since you never know.
Post-romantic evening cards can safely delve into cheese, but shouldn't be crude. Think, "I can't stop smiling."
Special occasion flower cards should be more effusive (i.e., think "mush") and personal. But keep things short. Consider referencing the occasion. For anniversaries, consider "Looking forward to another wonderful year." For birthdays, consider "Happy Birthday, (pet name)." For a job promotion, think "I thought these would look great on your new desk/in your new office" or simply, "I'm so proud of you." Of course, "I love you" always works for all the above.
Doghouse flower cards should be sincere, but should never grovel. Consequently, "I'm begging you" or "Please forgive me" are out. Keep your message short; don't write an incriminating novel. Consider, "I'm sorry," "Let's talk" or, if you must, "You were right."
Buying Flowers
Get your own florist. The other first step to making flower-giving easy is to befriend a florist. A good florist can walk you through your choices for any occasion, regardless of whether it's a fancy store or a supermarket stand. To find the man or woman who will be "your" florist and confidant, ask women who get lots of flowers. New mothers and other recent hospital patients are your best bet.
No luck with the recently hospitalized? Ask any SharpMan or woman. Once you have a couple of recommendations, consider stopping by the shop for a full-dress inspection. Ideally, the folks at your florist should be knowledgeable and helpful. If they're too "cool" to help a guy with questions, then they're too "cool" to deserve your hard-earned cash.
Making the purchase. Once you have the great florist, the rest is actually pretty easy. If you're picking up the flowers yourself, simply tell your florist how much you'd like to spend and the types of flowers or colors you'd like to incorporate in your arrangement. Specify if you'd like a formal or informal arrangement, or let the florist know what the occasion is. A good florist will help you choose each flower and work within your style and budget.
Making a purchase by phone. Of course, in a perfect world, all SharpMen would have the time to walk over to their florist and personally choose every flower that goes into Ms. Right's arrangement. Since the world isn't perfect, consider picking up the phone to your trusted florist, instead. For same day delivery, call as early as possible.
When placing an order, consider your budget and the types of flowers or colors you'd like to give. Give this information to your florist. If you're ordering an assortment of flowers rather than a bouquet of one type, the florist will list the flowers in stock that meet your description and match your budget. You're unlikely to recognize any of the names mentioned, so just go with the recommendations, or:
SharpMan Tip: For the truly fastidious, while on the phone, consider hopping online and searching for the flower names mentioned on the Web. In addition to your favorite search engine, try gardeners' Web sites like http://www.jacksonandperkins.com/.
Once you've agreed to the types of flowers, consider doing a quality check. Tell your florist what you were hoping the arrangement would say (i.e., impressive, modest, etc.) or just describe the occasion. Ask your florist whether the arrangement you've just ordered matches your description or the occasion. A good florist will not try to sell you more than you need, but will be frank if your budget doesn't match your expectations. If you find that the product isn't "enough" and you can't move up on the dollars, ask your florist to recommend less expensive flowers in the same color category.
Before hanging up, be sure to give your florist all the delivery details, i.e. name, address, company name, direct dial telephone number. If the flowers will be delivered to your SharpWoman's workplace, be sure to tell the florist her particular department and working hours, and be accurate.
Finally, realize that placing flower orders on any holiday, but particularly Valentine's Day and Mother's Day, requires early action. Believe it or not, a day or two early may not be early enough. Consider placing your order (and then confirming) a week before a major flower holiday. Otherwise, you're likely to pay more, get less (or worse, whatever others rejected) or risk spending all night combing the supermarket florists for the last wilted red rose in town.
Ordering flowers for your long-distance SharpWoman. Ordering flowers in another town is tricky. You can't rely on your trusted florist, so how do you ensure that the flowers you pay for will be the flowers she gets? You may think that what follows will be a plug for using the services of online florists or national flower delivery services.
While ordering based on an online picture may seem safe (she will supposedly get an arrangement identical to the one pictured), it's so impersonal. Why bother? Why send her the same mass-produced arrangement thousands of other women will get that day? Additionally, while there are several reputable online florists out there (www.marthasflowers.com; www.proflowers.com; www.flowerbud.com), perfect quality control is hard to achieve en masse.
Nothing beats a personal touch.
Instead, consider replicating your in-town process. Ask your florist to recommend a good local florist in your SharpWoman's town. No luck there? Consider visiting www.ilocalflorist.com for a directory of local florists.
Call the local florist yourself. In addition to the steps outlined in "Making a purchase by phone" above, take an extra minute to describe the type of container you want (if any), including the container's color, to ensure that your SharpWomen gets the style and quality you had in mind.
Got all that down? Now go out there and use those stems to your advantage…This article last updated on Tuesday 12th October 2010


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Christina Aguilera and Bette Midler joined in a celebration for billionaire Joe Hardy on Saturday January 6th.
It comes two for Christina Aguilera. First she was one of the several high-profile celebrities who surprised more than 500 guests with an appearance at the 84th birthday celebration for billionaire Joe Hardy, took place Saturday January 6th.
While she sang "Happy Birthday", fellow musician Bette Midler performed with an orchestra at Hardy's posh resort in southwestern Pennsylvania. Also on hand was comedian and actor Robin Williams who was the after-dinner performer.
The second for the singer is that she has just inked an international licensing agreement with Procter & Gamble Prestige Products to create Aguilera fragrances. The fragrance, expected to be for women, should be available at the end of this year.


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Peter Homa was named as the first chief inspector of the Commission for Healthcare Audit and Inspection (CHAI) in February.
He has now resigned from the post at the request of the organisation's chairman Sir Ian Kennedy.
The resignation will be seen as a set back for the government's plans to raise standards across the NHS.
Mr Homa was arguably the best qualified man for the job. He has served as chief executive of the current inspectorate, the Commission for Health Improvement, since it was established in 1999. He is expected to continue in that post.
A personality clash between Mr Homa and Sir Ian is believed to be the cause of his departure from the £165,000 a year post.
In a statement, he said: "Although, unfortunately, there were differences in approach, Sir Ian and I share the passion that CHAI should be a major force for the improvement of healthcare for patients."
Sir Ian said: "Peter is an outstanding figure in improving healthcare and has a huge amount to offer. I wish him every success."
Speaking in February, Sir Ian said: "I'm delighted that Peter has agreed to take on this new and exciting challenge. He is uniquely qualified and shares my determination that CHAI will be a force for improvement for patients."
'Serious setback'
Mr Homa's resignation has been greeted by dismay within the NHS.
Dame Deirdre Hine, a former chief medical officer for Wales and chairwoman of CHI, described it as a serious setback.
"I am saddened and concerned to learn that Peter Homa is not now to take up his post as chief inspector of the Commission for Healthcare Audit and Inspection, to which he was appointed only weeks ago.
"It is a serious setback for CHAI to have lost a chief officer of Peter's calibre at this early stage of its life.
"I have had the privilege of working with Peter as my chief executive for the past three and a half years.
"During that time we have broken new ground in establishing, for the first time, a body to which the NHS is required to account for the quality of the service it provides to patients.
"It is my view, and that of the CHI commissioners, that Peter's personal qualities of leadership and integrity and his unrivalled experience and expertise in the management of NHS organisations, and of CHI, made him the obvious and ideal choice for the chief inspector post in CHAI.
"We feel that he will be very difficult to replace in this role. He remains the much admired and respected Chief Executive of CHI."
Major contribution
Dr Gill Morgan of the NHS Confederation, which represents health service managers, said: "Peter Homa made a major contribution to NHS management and we are sad to see him go. We hope he will continue to contribute to the service and that his talents won't be lost."
She added: "It is important that momentum will be maintained and we hope that this setback will not interrupt the transition to the new organisation at this crucial stage."
CHAI is scheduled to start work in April next year. It will be responsible for carrying out inspections and ensuring standards are being maintained in NHS organisations across England and Wales.
It will take over the work of CHI, the Mental Health Act Commission, the National Care Standards Commission and some of the work carried out by the Audit Commission.
Sir Ian was appointed shadow chairman of CHAI in December last year.


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Police raid pirate film factory, seize over 6000 DVDs
A 42-year-old man has been arrested following a raid of a private house in Heywood, Greater Manchester. Police seized 40 DVD burners, three computers, printers, over 6000 counterfeit DVDs and £5000 in cash that were found on the premises.
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2 seek Democratic nomination for Mt. Pleasant mayor
Two candidates will be on the May 21 primary ballot seeking the Democratic nomination for Mt. Pleasant mayor.
There are no Republican candidates seeking the nomination.
Incumbent Jerry Lucia, 67, is seeking his eighth term. He said he would like to continue to serve a town that he has dedicated more than half of his life helping.
"I've spent half of my life in politics in Mt. Pleasant," Lucia said. "I was on council for six years, and I have served as mayor for 28 years. I feel that I have put a lot of hard work and effort into the borough in many projects over the years such as the Mt. Pleasant Glass and Ethnic Festival that I helped found my second year as mayor. That festival helps many nonprofit organizations in the borough, and I would like to see that continue. I also want to continue to see Mt. Pleasant stay a safe and good community. I feel that we have some very good ordinances that are geared toward the betterment of all of the citizens here in Mt. Pleasant."
John Rogacki, 70, is a former council member. In seeking the nomination for mayor, he hopes to serve the taxpayers while further opening the lines of communication in the borough.
"If elected I promise to serve to the best of my ability to represent all of the taxpayers and residents of the Mt. Pleasant Borough," Rogacki said. "I would like to make an effort to better open lines of communication, setting times for residents to visit and voice their opinions or concern. I will work closely and try to secure grants for our police, fire, and emergency medical services. I also want to aggressively deal with the drug problem that plaques our community. I would like to see Mt. Pleasant be a vibrant community as it was in the past."
Eleven candidates are seeking nominations for open seats on Mt. Pleasant Borough Council. There are seats open in each of the borough's four wards.
There are two four-year seats open in the 1st Ward. Republicans seeking the nominations are incumbents David Pritts and Cynthia Stevenson. On the Democratic ticket is Donald McHirella.
Pritts, 44, is seeking a second full term.
"I believe the most important role of our borough government is to keep all of our citizens safe," Pritts said. "I would say I am a conservative who will defend the Constitution. I stand for family values, and I believe in keeping God and values in our community. I believe in keeping taxes as low as possible and using public funds efficiently and for the best use of the whole community. I intend to work to improve the community in whatever way I can."
Stevenson, 62, is seeking her third term.
"I am a believer in limited government," Stevenson said. " It is the job of borough council to ensure, to the best of our ability, the safety of the town and its citizens. I will continue to strive for balance between those two ideas. I am on council to serve the citizens and not to further any agenda that benefits me personally. I am working to improve communications between council and citizens."
McHirella, 69, wishes to bring together what he feels is a divided community.
"The reason that I am seeking a seat on council is because I believe that the current leaders of Mt. Pleasant have governed in a way that has divided our community," McHirella said. "I would like to serve on council to heal this division and move Mt. Pleasant forward."
Two candidates are seeking one four-year term on council representing the 2nd Ward. Both incumbent Susan Ruszkowski and newcomer Robert Storey are Democrats.
"I feel very strongly about keeping our fire department, our police department and our Medic 10 as strong as they are, and I would not like to lose them," Ruszkowski, 61, said. "That is very important to me, as I feel we need our own departments to keep our borough as safe and secure as it can be. The safety of all of our residents is most important to me."
Storey, 56, wants to see more open lines of communication in the borough.
"I'd like to see better communication between the borough council and the people that they are representing," Storey said. "I feel that the present council has distanced themselves from the people of the community and they don't communicate well. They don't listen to what the members of the community have to say."
Incumbent Diane Bailey, a Democrat, was appointed to her seat in 2011, and will be the lone candidate for the two-year term opening in the Second Ward.
"I want to see the borough continue to operate responsibly and I want to see that we are financially responsible for what we are doing here in the borough," Bailey said. "I like to see the borough operating efficiently and also want to see a safe community — one that is safe for everyone."
There are two four-year term seats in the 3rd Ward and one two-year term seat. Five candidates are seeking their party nomination for the four-year term seats and three are also seeking the two-year term seat nomination.
Incumbent Fred McCloy, 66, is a Democrat. He wants to see the borough remain fiscally sound with no raises in taxes.
"We have gone eight or nine years now without a tax increase and I will work to see that it remains that way," McCloy said. "I want to see the borough continue to spend wisely while also trying to keep our property values high."
McCloy is seeking both the four-year and two-year term seats.
John "Jack" Caruso Jr., 52, is a Democratic who wants more transparency in local government.
Caruso is seeking both the four-year term and two-year term nomination.
"I'd like to see our government be more transparent to the public and be the voice of the people of this town for their ideas and their concerns," Caruso said. "I'd like to take this back to the council to be addressed."
Albert Beranek, 46, is a Republican and a former council member who had to resign his seat after moving from his home in the borough's 1st Ward.
Beranek is seeking the nomination for both the four-year term and two-year term seat.
"I am civic-minded and a businessman, and I am running for the people of Mt. Pleasant," Beranek said. "I want this to be a safe community in which to live and I want this to be a good community for families to enjoy."
Frank Pernelli, 39, is a Democrat. He is seeking the nomination for a four-year term seat.
"This election is about more than just property rights," Pernelli said. "It's about serving the people of Mt. Pleasant and I am ready to serve. I also want to get more of these vacant buildings which aren't generating any tax dollars into the hands of businesses which can."
Paul L. Wagner, a Democrat, is seeking a four-year seat.
"I have been a resident here for a number of years and I just felt that it would be a way to give back to the community," Wagner said. "I would like to help to insure the safety of the citizens and I think that it's very important to maintain the infrastructure. But safety is the most important and I want to make sure that the residents that reside within the borough of Mt. Pleasant are safe."
Scottdale Mayor Charles King, Republican, is running unopposed.
Robert Close, Democrat, is seeking the four-year seat in the borough's 1st Ward. Troy Soberdash, Democrat, is seeking the nomination for the four-year seat in the 2nd Ward. Jack Davis, Republican, is seeking the four-year seat in the 3rd Ward and L. Bud Santimyer, Democrat, is seeking the four-year seat in the 4th Ward.
Marilyn Forbes is a freelance writer.


text:
Under Tools>References... have you set a reference to the appropriate object library?
Is setting such a reference not mentioned on Dennis' site? I can't imagine it isn't.
The reference on my machine is Microsoft ActiveX Data Objects 2.5 Library.
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Hi all -
Using Win XP pro / Office 2003
Modified some ADO code I found on Dennis' site
To retrieve some records from Access database.
Compile error:
User-defined type not defined
Debug comes to line Dim cnn...
ThanksVB:'Create the connection Dim cnn As New ADODB.Connection Set cnn = New Connection cnn.Open DB_CONNECT_STRING
Full :
VB:Sub GetARData() On Error Goto ErrHandler '//Decalrations Dim wbBook As Workbook Dim wsData As Worksheet Dim rg As Range Dim strDBPath As String Dim strDBName As String '//Environment With Application .ScreenUpdating = True .Calculation = xlCalculationAutomatic .DisplayAlerts = True End With '//Objects Set wbBook = ThisWorkbook Set wsData = wbBook.Worksheets("Data") '//Processes '====================================== '==============Early Binding=========== '====================================== 'Early binding during development stage Dim XLObj As Excel.Application Set XLObj = New Excel.Application '====================================== '==============Late Binding=========== '====================================== 'Switch to Late Binding prior to deployment 'Dim XLObj As Object 'Set XLObj = CreateObject("Excel.Application") 'Fully quality the path to the .db Dim db_Name As String 'Change the path below to refernece .db on server prior to deployment strDBPath = "C:\Documents and Settings\wsnyder\My Documents\ASU_New\ar\" strDBName = "Invoices_xp.mdb" db_Name = strDBPath & strDBName Dim DB_CONNECT_STRING As String DB_CONNECT_STRING = "Provider=Microsoft.Jet.OLEDB.4.0;" & _ "data Source=" & db_Name & ";" & ", , , adConnectAsync;" 'Create the connection Dim cnn As New ADODB.Connection Set cnn = New Connection cnn.Open DB_CONNECT_STRING 'Create the recordset Dim rs As ADODB.Recordset Set rs = New Recordset 'Determines what records to show Dim strSQL As String strSQL = "SELECT Inv_Nmbr" & _ "FROM Tbl_Invoices ORDER BY Inv_Nmbr" 'Retreive the records rs.CursorLocation = adUseClient rs.Open strSQL, cnn, adOpenStatic, adLockBatchOptimistic 'Test to see if we are connected and have records Dim num As Integer num = rs.RecordCount Dim num1 As Integer num1 = rs.Fields.Count 'If cnn.State = adStateOpen Then ' MsgBox "Welcome to! " & db_Name & " Records = " & num & " Fields = "" & num1, vbInformation,"Good Luck -ws" ' Else ' MsgBox "Sorry. No Data today." ' End If 'Copy recordset to the range With wsData Set rg = .Range("A1") End With rs.MoveLast rs.MoveFirst rg.CopyFromRecordset rs rg.CurrentRegion.Columns.AutoFit '//Cleanup======================================= 'Close connection cnn.Close Set cnn = Nothing Set rs = Nothing Set wbBook = Nothing Set wsData = Nothing Set C = Nothing With Application .ScreenUpdating = True .Calculation = xlCalculationAutomatic .DisplayAlerts = True End With Exit Sub ErrHandler: MsgBox "Sorry, an error occured. " & Err.Description, vbOKOnly End Sub
Under Tools>References... have you set a reference to the appropriate object library?
Is setting such a reference not mentioned on Dennis' site? I can't imagine it isn't.
The reference on my machine is Microsoft ActiveX Data Objects 2.5 Library.
Last edited by norie; November 26th, 2005 at 05:09. Reason: Added info on library
Thanks Norie -
I thought I read somewhere, but forgot, how to set the reference through code.
I would prefer not to have to set the reference on each target pc I deploy
the app to.
Well what you want to do is use Late binding, there's an example of it (commented) out in the code you posted.
It actually pertains to the Excel object but you should be able to apply the same principles to the other objects.
Perhaps the site you got the code from has more information.
If you want to use early binding but programmatically add the reference(s), check out this thread
Kind Regards, Will Riley
LinkedIn: Will Riley
Thanks Will -
Can you point me or remind me to the advantages/disadvantages of eraly/late binding.
I was looking into ADO some months ago, but got sidetracked.
I pulled down Dennis; code and commented out the Late Binding
And added the comments :
Early Binding for Development
Late Binding for Deployment
But I do not recall why.
Rather than reinventing the wheel, here are a few good articles on the subject by people with more knowledge than me
http://word.mvps.org/FAQs/InterDev/E...ateBinding.htm - Dave Rado(MVP)
http://www.dicks-clicks.com/excel/olBinding.htm - Dick Kusleika (MVP)
http://peltiertech.com/Excel/EarlyLateBinding.html - Jon Peltier (MVP)
Kind Regards, Will Riley
LinkedIn: Will Riley
Thanks Will -
I attempted to run "Grab_References" from lasw10
GrabReferences added the worksheet, but nothing entered onto worksheet
Saved >> Rebooted >> same outcome
Left the GUID as is in the Workbook_open event in the code.
The comment refers to the ADO Ref Library which is what I want, though it does not specify version.
Tools >> references >> lists up to 2.8 on the development system (Office 2003).
I unchecked the reference, Saved, Closed, Restarted the workbook.
I ran the code to get the data from Access. Received same "User Data Type..." error message as previously.
I commented out Open and Before_Close Events, I checked the ADO 2.5 Library Reference.
Ran my code, I receive this error message:
Quite polite.Sorry,an error occured. Syntax error (missing operator) in query expression
Here is the SQL section of my code
Sorry so longVB:Dim strSQL As String strSQL = "SELECT Inv_Nmbr" & _ "FROM Tbl_Invoices ORDER BY Inv_Nmbr"
Thanks for the great help
I don't think this has anything to do with references or early/late binding.
It might be a typo but as far as I can see you have a mistake in the SQL string.
There should be a space between Nmbr and FROM.
VB:Dim strSQL As String strSQL = "SELECT Inv_Nmbr " & _ "FROM Tbl_Invoices ORDER BY Inv_Nmbr"
Thanks Norie -
The space was indeed the culprit.
Any thoughts on the binding stuff as well?
WillR pointed me to this thread
ADO Bind Programmatically
Can't seem to get it to work.
I suspect because the GUID is incorrect.
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text:
Study of Liver Transplant For End-Stage Liver Disease Caused By Chronic Hepatitis C Infection
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|End Stage Liver Disease Hepatitis C
|Drug: Daclizumub Drug: Tacrolimus Drug: Cyclosporine Drug: MMF
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|An Open-Label, Randomized, Prospective Multicenter Study To Compare The Efficacy And Safety Among 3 Immunosuppressant Treatment Regimens In Patients Receiving A Liver Transplant For ESLD Caused By Chronic Hepatitis C
- Freedom From Acute Rejection or HCV Recurrence or Treatment Failure [ Time Frame: 12 months ]Freedom from acute rejection (Banff>grade 2 with RAI score>4) or freedom from HCV recurrence (Batts/Ludwig>Stage 2, or >Grade 3) that requires HCV antiviral therapy or treatment failure (patient death, graft loss, premature withdrawal from study regimen or treatment with more than 1 dose of corticosteroids for presumptive rejection without a biopsy to confirm the rejection; reported values represent the "Number of participants with Freedom From Acute Rejection or HCV Recurrence or Treatment Failure"
- Freedom From HCV Recurrence Within First Year That Requires HCV Antiviral Therapy and Freedom From Treatment Failure [ Time Frame: 12 month post transplant ]Participants would have their blood drawn and tested for the HCV virus to determine if they had recurrence
|Study Start Date:
|July 2002
|Study Completion Date:
|January 2007
|Primary Completion Date:
|April 2006 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: tacrolimus and cyclosporine
immunosuppressant treatment regimens the intervention is antirejection treatment with the above labeled drugs tacrolimus and cyclosporine
Drug: Daclizumub
anti-rejection drug
Other Name: ZenapaxDrug: Tacrolimus
anti rejection drug
Other Name: Prograf
Active Comparator: MMF, tacrolimus and cyclosporine
immunosuppressant treatment regimensthe intervention is antirejection treatment with the above labeled drugs MMF tacrolimus and cyclosporine
Drug: Tacrolimus
anti rejection drug
Other Name: PrografDrug: Cyclosporine
anti rejection drug
Other Name: NeoralDrug: MMF
anti rejection drug
Other Name: mycophenolate mofetil
Active Comparator: daclizumub, MMFand tacrolimus
immunosuppressant treatment regimens
Drug: Daclizumub
anti-rejection drug
Other Name: ZenapaxDrug: Tacrolimus
anti rejection drug
Other Name: PrografDrug: MMF
anti rejection drug
Other Name: mycophenolate mofetil
Detailed Description:
End-stage liver disease due to Hepatitis C virus (HCV) infection is the most common reason for liver transplantation in the United States. Patients who have HCV will always carry the virus in their body. If patients respond to treatment, the virus is no longer active. This means that although the virus is still present, it is not currently causing damage to their liver.
Because recurrence of HCV is virtually universal in HCV positive transplant recipients and is associated with long term, possibly lethal complications, the search for the most appropriate therapies must also include methods to prevent or minimize recurrence or disease progression, if the goal of improving long term outcomes for these patients is to be achieved.
Corticosteroids and high doses of immunosuppressive agents have been associated with increased rates of HCV recurrence. Finding a regimen that provides adequate immunosuppression to prevent early and late rejection episodes, and minimizes steroid usage as well as high doses of other immunosuppressive agents is highly desirable.
This study is being conducted to determine the most effective immunosuppressive regimen that will prevent allograft rejection, minimize adverse events and at the same time, prevent or reduce the incidence of HCV recurrence following liver transplant.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patient has been fully informed and has signed an IRB approved informed consent form and is willing and able to follow study procedures for the full 2 years.
- Patient is a recipient of a primary whole/split, cadaveric/living donor liver transplant for end stage chronic Hepatitis C.
- Patient is > age 18.
- Female patients of child bearing potential must have a negative urine or serum pregnancy test upon hospitalization or within 7 days prior to enrollment and have agreed to utilize effective birth control throughout the study as well as for 6 weeks following study completion.
Exclusion Criteria:
- Patient has previously received or is receiving an organ transplant other than a liver.
- Patient has received a liver transplant from a Hepatitis B core antibody or a Hepatitis C antibody positive donor.
- Patient has received an ABO (blood group anti A, anti B antibodies) incompatible donor liver.
- Patient has fulminant liver failure with a life expectancy without a liver transplant of less than 7 days as defined by UNOS (Adult Patient Status 1, UNOS Policy 220.127.116.11: See Appendix C).
- Patient has renal dysfunction pre-transplant that, in the opinion of the investigator, will prohibit the use of calcineurin inhibitors within 72 hours post transplant.
- Patient is intubated, on vasopressors, is ICU bound, or has experienced a significant blood loss (greater than 5 units) 72 hours prior to transplant procedure.
- Recipient or donor is seropositive for human immunodeficiency virus (HIV) or HbsAg positive serology.
- Patient is to receive antilymphocyte antibody induction therapy, such as ATGAM (lymphocyte immune globulin), OKT3 (muromonab-CD3), Simulect (basiliximab), or Thymoglobulin.
- Patient has a known hypersensitivity to Prograf (TAC), HCO-60, CellCept (MMF), Zenapax or corticosteroids.
- Patient is pregnant or lactating.
- Patient has participated in a blinded trial or participated in a trial involving a non-marketed (investigational) drug within 3 months of enrollment.
- Patient has participated in a trial involving a market drug within 30 days. However, patients who participated in any interferon or ribavirin trials are permitted.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00163657
|United States, Texas
|Baylor Regional Transplant Institute - Baylor University Medical Center
|Dallas, Texas, United States, 75246
|Principal Investigator:
|Goran Klintmalm, MD
|Baylor Univeristy Medical Center
|Responsible Party:
|Baylor Research Institute
|ClinicalTrials.gov Identifier:
|NCT00163657 History of Changes
|Other Study ID Numbers:
ZEN159 ( Other Identifier: Baylor Research Institute )
|Study First Received:
|September 9, 2005
|Results First Received:
|February 23, 2012
|Last Updated:
|November 15, 2016
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
|Plan Description:
|No their is not a plan to make individual Participant data available
Keywords provided by Baylor Research Institute:
Hepatitis C Virus
Immunosuppressive Agents
Additional relevant MeSH terms:
Hepatitis A
Hepatitis C
Hepatitis, Chronic
Hepatitis C, Chronic
Liver Diseases
End Stage Liver Disease
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Enterovirus Infections
Picornaviridae Infections
RNA Virus Infections
Flaviviridae Infections
Liver Failure
Hepatic Insufficiency
Mycophenolate mofetil
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Calcineurin Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antifungal Agents
Anti-Infective Agents
Dermatologic Agents
Antirheumatic Agents
ClinicalTrials.gov processed this record on August 21, 2017


text:
Seattle Waterfront
This property presented a substantial landscaping challenge: a modern house with an outdated landscape.
Design goals for the project included:
- Creating flow and continuity as well as strong focal points throughout the landscape
- Establishing a water element without compromising the view
- Easy access from the deck to the lower landscape
- Providing year-round entertaining spaces and plant interest
Design elements included contemporary fences and screens, composite decking, contemporary water elements and gas fire place, welded iron planters to contain bamboo, drip irrigation and low voltage lighting.
Sustainable garden features include:
- Drip irrigation
- Edible plantings throughout the landscape
- Recycled top dressings, soils and fertilizers in all planting beds
- Recycled and crushed concrete in sub-grades under hardscapes
- All patios and entryway areas were sand set, ensuring that water drains through the surface to help recharge the aquifer instead of creating runoff that could contaminate critical spawning areas.


text:
I feel like a kid again in some ways.
Three months is a long time to not run, four is even longer. Almost four months ago I stopped running, cold turkey. From full gate to shut off just like that. After training for months to run back to back 50 milers it was weird and hard, but I had to. My knee was not doing well, at all. It's a bit complicated, but the story is in my posts. During that time I started riding again in earnest.
Fast forward to last weekend: A good Loopster friend of mine, we met at Rocky Raccon 50 was in town. We had supper together and then Saturday morning we met for a run. Some pretty impressive thunderstorms were doing their thing in the early morning hours. Once they cleared out we met for a run down the shore of Mobile Bay. It was incredibly humid. But it was great to run and chat.
We ran a bit over six miles and had a wonderful time. We took it easy, walked occasionally and just had a good time. We hadn't seen one another since Rocky, but it was as natural as, well, running.
On the drive home I began to reflect upon how simple running is. It is part of the wiring of our brains and bodies. It is what joyful children naturally do. It builds bridges between people and cultures. It is an amazing action of our bodies that has impact across the spectrum of our lives.
I am really glad to be able to run again. I don't know exactly where it will lead this time. I have some goals that are still unmet. I'm still in a rehab state, but I'm running and grateful.


text:
Algeria name World Cup squad
Portsmouth's Nadir Belhadj and Wolves' Adlane Guedioura have been selected in Algeria's World Cup squad.
By Richard Bailey
Last Updated: 02/06/10 4:35pm
Portsmouth defender Nadir Belhadj and Wolves midfielder Adlane Guedioura have been selected in Algeria's 23-man squad for the World Cup finals.
England's Group C opponents have also picked Benfica midfielder Hassan Yebda who spent last season on loan at Pompey.
Manager Rabah Saadane had to cut seven players from his preliminary squad including goalkeeper Mohamed Zemmamouche, defender Mohamed Meftah, midfielders Khaled Lemmouchia, Mourad Meghni, Lazhar Hadj Aissa and Hocine Metref and striker Chadli Amri.
Saadane has recently voiced concerns that his squad lack a cutting edge therefore it is a surprise that he has only named three recognised strikers meaning much of the creativity and threat will come from Wolfsburg midfielder Karim Ziani.
Squad in full
Goalkeepers: Fawzi Chouachi (ES Setif), Lounes Gaouaoui (ASO Chlef), Rais M'bohi Ouheb (Slavia Sofia)
Defenders: Laifaoui Abdelkader (ES Setif), Madjid Bougherra (Rangers), Carl Medjani (Ajaccio), Rafik Halliche (Nacional Madeira), Anther Yahia (Bochum), Habib Belaid (Boulogne-sur-Mer), Nadir Belhadj (Portsmouth), Djamel Mesbah (Lecce)
Midfielders: Hassan Yebda (Portsmouth), Mehdi Lacen (Santander), Yazid Mansouri (Lorient), Adlane Guedioura (Wolverhampton), Riad Boudebouz (Sochaux), Djamel Abdoun (Nantes), Fouad Kadir (Valenciennes), Karim Ziani (Wolfsburg) Karim Matmour (Monchengladbach)
Strikers: Abdelkader Ghezzal (Siena), Rafik Djebbour (AEK Athens), Rafik Saifi (Istres)


text:
Dear Readers: Last week, "Curious Reader" asked if mass shootings are the price of society's insatiable appetite for media violence. A furious defense ensued from the male panelists (see our Jan. 19 column), who pointed to mentally disturbed individuals as the cause of mass shootings, not their games, movies and music, which they held sacrosanct.I agreed with the first part — and promised to talk this week about the inconvenient truth that massive childhood doses of virtual violence aren't innocent either — and that they are causing previously unforeseen neuro-cognitive maladaptions and breakdown. — Lauren
But first, some panelists less captivated by virtual violence:
Hannah, 21, Sausalito: Media violence isn't the cause of mass shootings, but it is ridiculous to think it has no effect. Speaking as a kindergarten teacher, it is extremely important to protect children's lives from it. Children should be playing outside, getting dirty, building real connections, not shooting others in video games. Regarding the Newtown shooting, with input from the parent body, our school decided to shelter children from the news, which is part of the problem.
Lennon, 26, Los Angeles: As a hunter, I know from "killing" animals in video games, versus killing actual birds, games and movies don't come close to real experiences of violence and death. They've actually detached us from life more than ever before. Farming, hunting, loved ones dying in the parlor — these gave us real life-and-death experiences. Now we watch it on screens.
There is no one reason for mass shootings. But we humans ostracize anyone different: nerds, gays, the overweight, and especially the mentally unstable or emotionally awkward. With nobody to connect with, they fall through the cracks.
Why such individuals didn't take revenge through mass shootings in the past is uncertain, but doing so makes them a household name on par with John Wilkes Booth. It's absurd! People emulate what they see — yet the news saturates us with these killings.
Ryann, 16, Tustin: As a woman, I dislike video games that glorify war and hate. But every day, my younger brothers are on the couch playing their games or listening to rap. I wish I could ban violent movies and games for children under 18. They would grow up happier, healthier, more mentally stable.
Dear Readers: They would indeed — Ryann is correct. And here's why: Whenever we experience violence on a screen, our front brain informs us correctly, "This is not real." Unfortunately, our older, "reptilian" brain, designed for survival reactions, believes it is real.
Every time a violent act occurs, the reptilian brain sends alarm messages that trigger release of the powerful hormone, cortisol, which instantly creates billions of new neural links in the brain to deal with the "danger." When the "emergency" is over, all the neural links not involved in solving the danger are instantly dissolved by another hormone. This is how our incredible brain stays efficient and conditioned to its environment.
Or in this case, maladapted.
The average American spends five hours a day watching TV, absorbing 20 to 50 violent "bits" per hour. By age 18, that's almost 33,000 hours — containing over a million violent "events." What happens, any weight-lifter can tell you: the reptilian brain grows larger, the frontal brain smaller. Scientists are also seeing an alarming breakdown in inter-brain communication.
This means reduced imagination, critical thinking and literacy, more black-and-white thinking, more kneejerk behavior, reduced awareness of environmental signals (desensitization), earlier puberty (from age 15 to 11; the body must reproduce quicker in a world of constant danger), less inter-brain cohesion (more stress, anxiety, anger), and much more. Joseph Chilton Pearce, Jerry Mandera, Jane Healy are just some of researchers trying to get everyone's attention above the din of the entertainment industry. I refer you to their work.
Fact: We pass the sins of our lifestyle genetically to our children. Often the first couple of generations display minimal outward symptoms. But if we don't wake up and stop feeding our young this literally insane "mental diet" (sorry, even 5,000 hours is insane), the mental dysfunction of the next generation will ruin us. — Lauren
Straight Talk TnT is a 501c3 nonprofit. Ask a question or join our work with a donation at www.StraightTalkTnT.org or P.O. Box 1974, Sebastopol, CA 95473.


text:
During a recent game, Brooks Laich got hit by a puck in a particularly sensitive area, forcing him to leave the game for a bit. He discussed the injury with the Junkies on 106.7 on Wednesday.
"Oh, man. And then some," he replied, when asked if he got hit in the aforementioned area. "I took a shot…the puck came right…I was close to the guy, and it came right underneath the can and caught the low-hanging fruit directly. A sniper shot direct to 'em. The left side, it was just miserable. It just dropped me like a sack of hammers, man."
The shot caused Laich to go down, and stay down.
"I was crawling off the ice," he continued. "I couldn't get up and I crawled off and our athletic trainer, our head medical trainer, Greg Smith, asked me how I was doing. I was like, 'Man, I'm in so much pain.' And he goes, 'Well, you may have cracked it in half.' I was like, 'Seriously, that can happen?' And he said, 'Yeah. You might have to go to the back to check it out. If you're experiencing that much pain, that can happen.' I said, 'Oh, man.' So I had to go to the back to make sure things were okay."
And just how do you check to make things are okay?
"Just the ol' hand test. There was a couple doctors there, and another medical trainer, and I was like, 'Hey, boys. Don't worry, I got this one.' If it was really really bad…like, I knew something wasn't wrong. It was just a stinger, I just got hit there. But if there was something really wrong I would have left it up to them."


text:
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Jaros blogs at "Postings from the Post-Apocalypse."
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text:
Brigadier General Frank Wormald CB, late 12th (Prince of Wales's Royal) Lancers Cdg, 5th Cavalry Brigade.
Frank Wormald was born in February 1868 to a local mill-owning dynasty that had for a number of generations run the blanket manufacturing firm of Wormald and Walker in Dewsbury, Yorkshire. He was the son of John and Annie Wormald and husband of Gwynifred Wormald of 10 Walton Place London (this property is adjacent to Harrods).
He joined the army in 1889 and saw service in the Boer War, commanding a mobile column of his regiment, the 12th (Prince of Wales's Royal) Lancers. In 1912 he took command of his regiment. Frank was a successful big game hunter in India and Africa and was a well known polo player.
On 28 August 1914 'C' Squadron of the 12th Lancers, led by Lieutenant-Colonel Frank Wormald made a most successful charge at Moy against squadrons of the 1st and 2nd Garde Dragoner (Prussian Dragoons) supported by the fire of A and B Squadrons, J Battery RHA and the Scots Greys; he was wounded in this action. He rejoined his regiment three weeks later, commanding it until July 1915 when he was promoted to command the 5th Cavalry Brigade.
On 3 October Frank was killed by shrapnel whilst going around the trenches at Vermelles where men from his brigade were employed clearing up the battlefield and reconstructing trenches. He is buried at Nedonchel Churchyard in France.
Within Holy Innocents Parish, very close to the Wormald and Walker Mill in Dewsbury, the following is recorded:
In Loving Memory of
Brigadier General Frank Wormald C.B
Born 10th February 1868
who was killed in action
Near Hulluch, on
the 3rd October 1915 when in command of the
5th Cavalry Brigade. He was severely wounded on
August 28th 1914 at Cerizy when commanding his
Regiment the XII Royal Lancers. He also served
with distinction in the South African Campaign
1899 - 1902 both with his Regts the XII Royal Lancers
and in command of a mobile column
He is buried at Nedonchelle in France
Non Immemor
"Till the Day Break"
3 October 1915
Research by David Tattersfield MA, WFA Development Trustee.


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Putting Marketing Ideas into Action (Successful Lib Professional Series No. 45004000)
Most of the existing literature that could help LIS managers take the first steps into marketing their service, is geared toward profit-making organizations, thus reinforcing the prejudice that marketing is about making money rather than about satisfying customer needs. Many libraries and information units have suffered from the demotivating effects of such misconceptions, and are in danger of missing opportunities to communicate proactively with their customers about what they want from the library service. This introduction to marketing techniques is aimed specifically at the information world, and should enable LIS managers to examine where their service is now, where they would like it to be, and how to start moving in the desired direction. It is designed to serve as a deskbook when help is needed with specific projects. Examining tools such as public relations, advertising, direct mail, exhibitions and websites, it addresses the questions: what is marketing and why should libraries use it?; who are your potential customers?; what do you want to say, and how do you want to say it?; and why should you invest time evaluating your marketing activities? Containing exercises to help with getting started in marketing, the guide offers a hands-on approach. Written in clear language, it interprets the jargon of marketeers and provides examples and case studies relevant to the information provider.
Please visit Help Page for Questions
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text:
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University of Notre Dame golf coach Jim Kubinski has revealed Liam Cox's leadership qualities played a part his decision to offer him a scholarship at the US university.
Hampton School student and Surrey U18s captain Cox, who will lead his county at the inaugural Olazabal Trophy in Spain next month, will soon be clocking up the airmiles having agreed to move across the Alantic next year.
The 17-year-old, who has long held an ambition to study and play golf in North America, is already an England international and Kubinski expects him to play an important role for his team.
"Liam's results are easy to see. Perhaps more impressive, though, are the traits he possesses, things which will allow him to be successful at the next level," he said.
"His maturity, polish and discipline come through in spending any time with him.
"Liam has a great golf swing and has played on a number of top junior teams in the UK.
"He has not only played on those teams but has often been in a captain's or leadership role. ."
Cox added: "Notre Dame has the opportunities for me to become the best student-athlete I can be."


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Wonderful cruise on a Gem of a ship!!: Norwegian Gem Cruise Review by buffygirl
Overall Member Rating
Wonderful cruise on a Gem of a ship!!
Destination: Eastern Caribbean
Embarkation: New York (Manhattan)
Anyway, we had to pass thru the pool area to get to the garden cafe and the pool area consisted of 2 pools & 2 hot tubs. One pool for kids/adults and another one strictly for adults. The kids pool had a cool water flume. There were plenty of deck chairs and an entertainment gazebo in the center where musical groups such as "new Season" would rock it out with Caribbean music. ( they are a phenomenal group) It was a great area to just hang out More and listen to good music. The ship itself was colorful and the carpeting was vibrant- blues, oranges with nautical images of fish, dolphins. Very pretty. On each floor by the stairs, there were huge pics of whales & various marine life- quite beautiful to see.
Our cabin-room 5506-Inside/oceanview with porthole was very good. I was concerned about being in a room with just a porthole, but it was quite good. It offered plenty of sunshine and the room was a good size for 2 people. The bathroom shower had a glass door, which I liked, and it was a decent size. Our cabin Steward-Garfield was such a cool dude. He was friendly & very respectful. We enjoyed chatting with him on the few days we didnt sleep late. LOL. He kept our room clean & tidy and kept the room stocked with clean towels.
The ship itself offerred a bowling alley (pretty tricky trying to keep a bowling ball straight-LOL) a rock climbing wall, a basketball court, running track, fitness room (AS IF!!!- LOL) & various lounges. There was always something to do on the ship. My pal Mauricio treated me to a wonderful massage/facial at the Spa for my birthday. It was very good but pricey. Look for promotions & discounted services in your daily cruise letter, you could save a couple of dollars, especially on port days.
The Gem provided a Nickolodeon program for kids-characters such as Dora, Spongebob, Patrick & the fairly odd parents crew delighted the kids & adults alike. Even though there were kids onboard, I never felt like the ship was being overrun with them-this cruise definitely had an older clientele which I thoroughly enjoyed. A lot of older, retired folks.
The ships entertainment was excellent!! The cruise director Ben and his staff really did a great job keeping us entertained & satisfied. I especially loved Ben's assistant director-"Nacho". He was soo funny & energetic!! The production staff was wonderful too-the dancers and singers worked very hard. Energetic dance routines & singing that could rival broadway!! The game shows were the craziest, funniest events onboard!! OMG!! I laughed so hard at the "dancing with the gem stars" competition & at the "Quest" competition. Dont miss these events!! I really enjoyed 2 entertainers-Brian the piano man & Leo the guitar man. They were both excellent and provided quality entertainment. Leo played his guitar and sang oldies & contemporary music. Very good singer with an easy going personality. My absolute favorite was Brian-he played the piano quite beautifully and played old classics- for my birthday he played "what a wonderful world" and dedicated it to me. It was such a heartwarming gesture- I was truly grateful for that. It was during this evening with Brian that we met 2 delightful folks from upstate NY- Terry & Charlie. Charlie you could tell loved music and he got up a did a duet with Brian. AWESOME!!!! Another evening, we decided to relax & listen to Brian's tunes again & ran into Terry & Charlie. I was talking to Charlie about the movie "Casablanca" & how I had forgotten the love song for the movie. He asked Brian if he could sing the song- and he got up and sang the "Casablanca" love song- even though his voice was a little hoarse, he sang his heart out and left me dabbing my eyes. It was a beautiful moment-and it was appreciated in a way that he will never know. So thank you to Brian, Charlie & Terry- you helped create a "cruise moment."
For my birthday I also went to the specialty resaurant- "Cagneys"- awesome steakhouse!!! I paid an additional 30 bucks, but it was well worth it. EXCELLENT RIBEYE STEAK!!!!! Its a must do!! Service was wonderful and my waiter Narcisso was a gentleman! The hostess Pamela Cruz was very sweet and remembered my name.
The ports were all great. First stop San Juan, PR- we didnt do a shore excursion. We just walked the streets of San Juan and went to a local restaurant- "hecho en casa" which was great!! grilled porkchops, sweet plantains, rice & beans.......authentic puerto rican cuisine!! Second port-St Marteen was beautiful. We did the Orient beach excursion- beautiful beach with nice waves, white sand, good lunch & some naked people!! lol. Just a few topless women- didnt bother me at all. If you are uncomfortable with public nudity, this might not be the beach for you. Beach chairs were complimentary but umbrellas were 3 bucks. Third port-St Thomas- My pal did the Captain Nautica Snorkeling excursion-and he enjoyed it. I opted to have a lazy day on the ship and watched "ironman 3" and caught up on some sleep. Last port-Samanaa, D.R- we did a shore excursion to "cayo levantado" beach. We took a tender from the ship to the beach. There was no port or pier at this location. Very nice beach with a few places to buy food & souvenirs. The water was very calm-no waves to speak of. There were plenty of complimentary beach chairs-but get there early to get one.
Lastly- I cant finish my review without mentioning a very special lady- "Tania" a hostess at the Garden Cafe. As we entered the garden cafe buffet-we were greeted by Tania & her bottle of hand sanitizer. She greeted us with " HAPPY, HAPPY,WASHY,WASHY-GOODMORNING!!" & proceeded to spray our hands and melt our hearts at the same time. She is truly the happiest person on that ship & her happiness is infectious!! She is kind, warm & super friendly!! LOVE HER!!!
Disembarkation day-we ate at the garden cafe & Tania was nowhere to be found!!! We wanted to say goodbye & couldnt. As we approached the gangway to leave I heard a familar voice and saw TANIA!!! She was there!!! She was sending us off with her cheerful "happy, happy!!" and it was so fitting that she was the last crew member that we would be see.. So to answer the question- "Did I return a Norweigan?" ABSOLUTELY!!!!!!! Service, staff, entertainment, food, ports, everything was wonderful. I will cruise Norweigan again and this time bring the whole family!! Thanks to Mauricio-my cruise buddy for a wonderful time. Remember, its about the company you keep, the food you eat and the people you meet!! Happy Cruising!! Less
Published 04/22/14
Cabin review: 5506
I was hesitant booking the ocean view/porthole since I've always stayed in a balcony room. However, I was pleasantly surprised. The room was comfortable enough for 2 people and there was plenty of sunshine . I never felt claustrophobic , which was great!! The twin size beds were comfortable & the mini fridge was cold & stocked with assorted beverages ( fee). The bathroom was decent & the shower had a sliding glass door, which I felt was better than a shower curtain. Overall-very good room.
Read Cruise Critic's Norwegian Gem Review >>
Wonderful Trip!!
9 days....nice variety.....sol...
First Time Cruiser - NY >>> Po...
Who would ask for anything mor...
Perfect Cruise!
Amazing Alaska
Anniversary on the Booze Cruis...
Poor Planning & Execution
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text:
Blono Buccellati from "JoJo's Bizarre Adventure" is now a fully posable figure from Medicom! He's about 30cm tall, and comes with some amazing accessories: several interchangeable hands, an extra head, a turtle with a key in its back, and a fabric manga panel with a zipper in it (courtesy of his Stand, Sticky Fingers? You decide!)! Order now and prepare to get bizarre!
Please note that the photos shown are of a prototype; the production version may vary.


text:
Keith Shimada / Special to the Home News
Thursday, Jan. 29, 2009 | midnight
Professional drag racer and Boulder City resident Duane Shields is used to the constant rule changes administered by the National Hot Rod Association.
Shields, a 12-year veteran of drag racing, has seen the fuel requirements for his top alcohol dragster division change five times in his career.
The association lowered the maximum amount of nitromethane allowed in fuel to 96 percent for the 2009 season. The two-percent change effectively slows down the alcohol-fueled dragster and keeps the ever-improving automotive technology at bay.
"It does make a huge difference." Shields said. "It takes us a while to overcome these rule changes. We have to change the machinery, parts and other things to stay on top."
The change also was made to increase the parity with the blown-alcohol dragster, the other type of vehicle that competes in the top alcohol dragster division but saw no rule change.
Shields said the new fuel has added about one tenth of a second to his time.
He spent Jan. 17 and 18 at the Las Vegas Motor Speedway's Blast Off Open Test Session with his crew trying to figure out ways to get back that time before the race of the season, the Winternationals in Pomona, Calif., Feb. 5 to 8.
"We try to test a lot and try new parts to see what works best," said Dana Hopewell, Shields Racing crew chief. "You win and lose by thousandths of a second, so a tenth of a second is huge."
After finishing last season a respectable fifth place in the NHRA national top alcohol dragster division, Shields was expecting to compete for a national championship this year.
He recorded the fastest run of his career, 5.17 second run at a national event in July, but doubts he will be able to reach that time.
"We have to figure out if the things we have changed are creating good things or bad things," he said.
While the rule-change took Shields by surprise, he hasn't thrown in his hat for the season.
He has won the Winternationals twice in the last three years and uses the race to gauge where he stands with the rest of the pack.
"We were very competitive on the national level because the tracks are usually better," Shields said. "Our car is usually one of the top running cars out there. Controlling that power is key to it."
Sean Ammerman can be reached at 990-2661 or [email protected].


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(CNSNews.com) – Rep. Randy Forbes (R-Va.) would not say if President Barack Obama made a true or false statement when he said of the Affordable Care Act, "If you like your insurance plan, you will keep it."
"Well, based on the facts that have come out it doesn't seem that it was accurate," Forbes said when CNSNews.com asked if that was a true or false statement.
When asked if he was saying that Obama's statement was false, Forbes said: "I'm saying based on the facts that I've seen, it just doesn't appear to be accurate at this point."
On April 1, 2010, a week after he signed the Affordable Care Act, Obama repeated the pledge he had frequently made during the national debate over the bill – vowing not only that people could keep their plan if they liked it, but that no one would be able to take it away from them in the future.
"So now that this bill is finally law, and all the folks who've been playing politics will finally have to confront the reality of what this reform is, they're also going to have to confront the reality of what it isn't," Obama said in his April 1, 2010 speech.
"They'll have to finally acknowledge that this isn't a government takeover of our health-care system," he said. "They'll see that if Americans like their doctor, they will keep their doctor. And if you like your insurance plan, you will keep it. No one will be able to take that away from you. It hasn't happened yet. It won't happen in the future."
The president was asked about this promise during his news conference on Thursday.
"With respect to the pledge I made that if you like your plan you can keep it, I think – you know, and I've said in interviews – that there is no doubt that the way I put that forward unequivocally ended up not being accurate. It was not because of my intention not to deliver on that commitment and that promise."
Obama said when he made the promise he was thinking about people with employer-based health care, Medicare, and Medicaid – not the five percent of the population in the individual market.
"You have an individual market that accounts for about 5 percent of the population. And our working assumption was —my working assumption was – that the majority of those folks would find better policies at lower cost or the same cost in the marketplaces and that there – the universe of folks who potentially would not find a better deal in the marketplaces, the grandfather clause would work sufficiently for them. And it didn't. And again, that's on us, which is why we're – that's on me.
The complete exchange between CNSNews.com and Forbes follows:
CNSNews.com: Congressman Forbes can I ask you a question?
Forbes: Sure.
CNSNews.com: I'm Penny Starr with CNS News.
Forbes: Aha.
CNSNews.com: How are you?
Forbes: O.K.
CNSNews.com: After President Obama signed the Affordable Care Act, he said 'If you like your health plan you will keep it. No one can take that away from you. Not now or in the future.' Was that a true or false statement?
Forbes: Well, based on the facts that have come out it doesn't seem that it was accurate.
CNSNews.com: Are you saying it was false?
Forbes: I'm saying based on the facts that I've seen it just doesn't appear to be accurate at this point.
CNSNews.com: O.K. Thank you.


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Watch: Islanders' Quine scores power-play goal in 2OT
New York's Alan Quine beat Panthers goalie Roberto Luongo in the second overtime to give the Islanders a 2–1 win on Friday night. New York now leads the series 3–2.
First Easter, now Passover. Alan Quine moves the #Isles to one win away from Round 2 of the #StanleyCupPlayoffs. pic.twitter.com/9t63H0CYtt— Elite Sports NY (@EliteSportsNY) April 23, 2016
However, it was a save in the first overtime by Islanders netminder Thomas Greiss that would end up being vital in the game.
Greiss was put in a tough situation that not too many goalies see in Stanley Cup Playoff history, and he came up huge. The Islanders goaltender was up against an overtime penalty shot. It was only the third in playoff history. In the 1-on-1 situation it was Greiss who stopped Aleksander Barkov's bid to end the game.
Thomas Greiss robs Barkov on the penalty shot in OT pic.twitter.com/mzWwpYJzNm— Pete Blackburn (@PeteBlackburn) April 23, 2016
This tweet gives a little background info into the history of overtime penalty shots. Spoiler: Jagr is a true playoff veteran.
There have been 3 OT penalty shots in NHL playoff history.— Tim Reynolds (@ByTimReynolds) April 23, 2016
One in 1996. One in 1998. One tonight.
All missed.
Jagr played in all 3 games.
- Nate Mata


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Reviews: Anonymous
- Anonymous
- Australia, Female, 18-24
- Novice Nomad
St Christopher's Inn Canal, Paris, France
No customer comment
- Anonymous
- Australia, Female, 18-24
- Novice Nomad
Bada Bing Hostel Istanbul, Istanbul, Turkey
This place was definitely no better than average. We had to share a bathroom with males (including showers), which I don't think is right. Also, the Bada Bing Tour Shop caused us to miss our overnight bus, as we were told by them to catch the wrong shuttle.
Hostelworld Mobile Apps
Book on the go with the new Hostelworld mobile apps.


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|Home > National News > Article
|Monday June 10, 2002
The researchers hope it might be possible to cure diabetes by transplanting insulin-producing tissue from pig foetuses into people long before the disease takes hold.
Pig tissue transplants have been carried out overseas to try to treat diabetes, Parkinson's disease and liver failure, but are on hold in Australia while the risks are reviewed by the National Health and Medical Research Council.
The advantage of the inbred line is that it might be possible to identify and disarm viruses in the pigs' DNA. Because the pigs are inbred, scientists know the DNA they are dealing with.
Researcher Dr Wayne Hawthorne said the latest results were promising. Fragments of pancreas from foetal pigs were transplanted into adult pigs, in organs such as liver and kidney. The tissue grew and matured and began to secrete insulin after several months.
Professor Allen said that with 100,000 people with Type1 diabetes in Australia, the demand for human tissue for transplant would never be met. Pig tissue was a "potential long-term solution".
The transplant researchers first found out about the isolated Kangaroo Island pigs when the hairy, feral animals failed an audition for the movie Babe.
Two animals, dubbed Ma and Pa, were selected for a concentrated inbreeding program in 1994 by the team, which includes researchers at St Vincent's Hospital and the Walter and Eliza Hall Institute in Melbourne.
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In this section
No babes, but they could be stars
Queen's Birthday honours list
Steel row to hit car firms
Jail agony recalled in protest at visit
Vaccine supply dries up
East Timor move to combat AIDS
Adler accuses program of 'unfair smear' over US broker's link to Mafia
Hoteliers seek to muffle complaints over noise
Tree plantations tipped to treble
Do the crime, do the Mac time
Church admits to silencing victims
Pratts complete the awards double
Abbott's threat to cut state funds
Church admits silencing of sex abuse victims
Repent, golf club orders protester
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Thursday, 29 November 2012
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Category: Zelda - Rating: R - Genres: - Characters: Anju,Link - Warnings: [Y] - Published: 2008-02-12 - Updated: 2008-02-12 - 374 words
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text:
Hi guys,
Why I can't limit the length of TEXT type in phpmyadmin?Is this a bug?
I entered like this,
type: TEXTlength/values: 5000
and also I tried like this,type: TEXTlength/values: 5,000
When I view the structure of the table it shows like this,
Isn't it suppose to be look like this?,
Can someone explain please.
those numbers in parentheses behind some datatypes might be making you think that they somehow "limit" the number of characters or digits that the column can hold
this is ~not~ what they do for integer datatypes
INT(4) and INT(10) and INT(937) will all hold exactly the same range of numbers
the numbers in parentheses behind CHAR and VARCHAR are required and ~do~ limit the length of the values
numbers in parentheses behind TEXT and BLOB and their similar datatypes are not permitted
@r937 ;It's really nice to hear the answer from a master.Thanks again master.
By the way, so what is the use of the integer length?
INT(4) and INT(10) and INT(937)
If you use it with a padding option then the number gets padded out to the specified length if it is shorter. If you don't use it with a padding option then it makes no difference at all.
specifically, ZEROFILL
Thanks guys.


text:
I grabbed a Cigar Aficionado baseball hat from the closet on Saturday as I set out to forage for dinner in the local farmer's market. Early September harvests are bountiful this year in the Hudson Valley, so it was great to pick through the heirloom tomatoes, the last of the sweet corn crop and fresh peaches. The stalls were packed with people on a sunny morning.
We're lucky to have a Long Island fishmonger at the market, too. I had already cleared a scallop entrée for dinner with my wife, and sure enough, he had some fresh scallops waiting for me. As he began to fill up a plastic bag, he said, "Cigar Aficionado, I read that magazine all the time."
Although I usually don't say much, I said, "Yes, I'm the executive editor of that magazine."
"Really," he said. I apologized for not having some cigars with me to give to him. We had a brief conversation about what kind of cigars he liked, and then I went on my way.
But I was reminded later just how often I'm surprised when I'm out in public by people saying they love cigars or that they read the magazine or both. They love to talk about cigars, and want to know everything they can.
In the magazine's early days, back in the mid-1990s, it was always exciting to hear from readers, in part because it made us feel like we're weren't alone. It felt good to know we were building a community.
I'm gratified to know that the cigar clan has spread far and wide. Whether it's on a golf course, in an airline terminal, walking down the street or buying fish at a farmer's market, it is always fun to know there are fellow lovers of the leaf in every walk of life. If you're like me, and there's some hint that the person shares your passion for cigars, take the time to stop and talk with them. We may not be a huge community, but it is important to keep the clan alive and thriving.
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text:
Mr. McCONNELL. If the Senator will yield on that point, it is my understanding, and is it not correct, that these are not jobs sometime in the future but these are, in fact, jobs that just as soon as the President would sign off on this, this project is ready to go. We don't have to borrow any--the government doesn't have to borrow any money and they don't have to try to stimulate anything. This is a project, as I understand it, I would ask my friend from North Dakota, that is literally shovel ready and will not cost the government a penny?
Mr. HOEVEN. This is a project that is absolutely ready to go and will not cost the Federal Government one penny. It puts 20,000 workers on the job right away.
The hurdle was the route through Nebraska, but we have now worked with the State of Nebraska. They have had a special session. They have set up a process to clear that part of the route. Our legislation says within 60 days after passage of this bill the route is deemed approved. That is after 3 years of process through the EPA.
So we are ready to go. We have addressed the issues. We can put these people on the job now if we can get the Presidential approval.
Mr. McCONNELL. In fact, I would say to my friend, the Senator from Nebraska is on the Senate floor with us right now. He could further underscore that the people of Nebraska, having now satisfied the concern they had earlier about location, seem to be ready to go.
Mr. McCONNELL. Could I ask one further question of either or both of the Senators--and Senator Isakson as well.
I understand there is a suggestion that there may be political concerns on the President's part, and we all know that most environmental groups are very much on the Democratic side. But is it not the case that there are a number of unions in the country--most of which, certainly, do not support Republicans anywhere I know--that also feel passionately about this issue and would like to get to work? Is that not the case?
Mr. McCONNELL. Could I ask the Senator from Nebraska a further question?
It strikes me--correct me if I am wrong--that America not going forward does not prevent this from happening, just in another country. And a good option for the Canadians might well be to just ship this product to China. Is that not correct?
Mr. McCONNELL. Just one final observation, and then I am going to leave the colloquy to all the rest of my colleagues. But it strikes me--and I wonder if my colleagues agree--this is about as close to a no-brainer as we will ever run into in America. There is no government money.


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A contemporary American road trip, through the eyes of a young blind man. It's a wonderful ride. Read more
"Touch and Go is a strong debut — a high-velocity vision quest that keeps surprising and surprising." – Jonathan Franzen
"One of the year's finest fiction debuts." – Publishers Weekly
"A stunning vision of the fractured modern American family." – Booklist
"A rare experience... Beautifully written... Unforgettable." – Santa Cruz Weekly
Touch and Go is available now from your local bookstore, or by clicking one of the links below.Listen to Thad read from Touch and Go on True Fiction Radio True Fiction Radio is real stories and authentic lies, produced by Richard Stockton and Wallace Baine.


text:
- Description
- Tags
- Reviews
Furniture of America Colebrook Living Room Set in Beige
The contemporary look of this sofa will bring great warmth and comfort to any home. Beige and charcoal fabrics are the options for the set, as well as the contrasting pillow print. A centerpiece ottoman with the same print as the pillows is available for both color variants.
3 Piece Living Room set includes: Sofa, Love Seat, Ottoman
Colebrook Living Room Set Offer:
1 x Sofa
1 x Love Seat
1 x Ottoman
Style: Transitional
Color/Finish: Charcoal, Beige
Material: Fabric
Pillows Included
Optional Ottoman Available
Available in 2 Colors
Sofa: 82"W X 38"D X 37"H
Love Seat: 59"W X 38"D X 37"H
Ottoman: 41"L X 41"W X 18"H


text:
Media Advisory
20 February 2014
The thick fog covering Wellington this morning has meant that most flights have been grounded until further notice.
We ask that all travellers check with their airline or on the Wellington Airport website at www.wellingtonairport.co.nz on their flights status.
The airport hosted 29 passengers overnight due to the weather disruption. The airport took their contact details, let them know of the emergency and safety procedures and provided them with an area where they could rest.