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Welcome to E-Books Directory
This page lists freely downloadable books.
Compiler Construction
E-Books for free online viewing and/or download
e-books in this category
Crafting Interpreters: A handbook for making programming languages
by Robert Nystrom - craftinginterpreters.com , 2015
This book contains everything you need to implement a full-featured, efficient scripting language. You'll learn both high-level concepts around parsing and semantics and gritty details like bytecode representation and garbage collection.
(504 views)
Compiler Construction
by William M. Waite, Gerhard Goos - Springer , 1996
Our intent is to provide the reader with a firm theoretical basis for compiler construction and sound engineering principles for selecting alternate methods, implementing them, and integrating them into a reliable, economically viable product.
(1396 views)
Compiler Design in C
by Allen I. Holub - Prentice-Hall , 1990
The approach is similar to that taken by Tanenbaum for operating systems in the C-language that implements all algorithms. The book presents the subject of Compiler Design in a way that's understandable to a programmer, rather than a mathematician.
(2428 views)
Write You a Haskell: Building a modern functional compiler from first principles
by Stephen Diehl - StephenDiehl.com , 2015
We will build a small functional language called Fun, complete with a parser, type inference, datatypes, pattern matching, desugaring, typeclasses, higher-kinded types, monadic IO, arbitrary-rank polymorphism, records, Core language, etc.
(1627 views)
ROSE Compiler Framework
- Wikibooks , 2014
The goal of this book is to have a community documentation providing extensive and up-to-date instructional information about how to use the open-source ROSE compiler framework, developed at Lawrence Livermore National Laboratory.
(2085 views)
Implementing Programming Languages
by Aarne Ranta , 2012
This book follows a theory-based practical approach, where theoretical models serve as blueprint for actual coding. The reader is guided to build compilers and interpreters. The solutions are moreover portable to different implementation languages.
(4175 views)
Compiler Construction
- Wikibooks , 2011
The purpose of this book is to provide practical advice on writing a compiler, together with some examples of both compilers and interpreters, in order to break away from the concept that building compilers and interpreters are impossible tasks.
(4166 views)
Compiler Design: Theory, Tools, and Examples
by Seth D. Bergmann - Rowan University , 2010
This is an introductory level text for compiler design courses, that emphasizes problem solving skills. The concepts are clearly presented with sampler problems and diagrams to illustrate the concepts. The text also covers lex and yacc.
(3948 views)
Compilers and Compiler Generators
by P.D. Terry - Rhodes University , 1996
Designed for computer science students studying for a second year course in compilers/programming language translation, this text manages to combine theory, applications and use of compiler writing tools to give a solid introduction to the subject.
(3710 views)
Let's Build a Scripting Engine-Compiler
by S. Arbayo , 2010
This is a very hands-on approach to crafting a compiler and it does not follow any pre-defined set of rules. It is the author's intent to take some of the mystery out of what goes into making a working scripting engine - compiler.
(4378 views)
Lightweight Compiler Techniques
by Nils M Holm - Lulu Press , 2006
This book explains compiler construction in simple terms and by means of practical examples, but without avoiding the fundamental theory. It does not stop where other books do, and takes you on a tour through the whole compilation process.
(5162 views)
Language Translation Using PCCTS and C++
by Terence John Parr - Automata Publishing Company , 1993
This book is a reference guide for the parser generator ANTLR, ANother Tool for Language Recognition, and the tree-parser generator SORCERER, which is suited to source-to-source translation. It is valuable to scientists, engineers, or programmers.
(7392 views)
Bison: The Yacc-compatible Parser Generator
by Charles Donnelly, Richard Stallman - Free Software Foundation , 2009
Bison is a general-purpose parser generator that converts an annotated context-free grammar into an LALR(1) or GLR parser for that grammar. You need to be fluent in C or C++ programming in order to use Bison or to understand this manual.
(6059 views)
The Power PC Compiler Writer's Guide
by Steve Hoxey, at al. - Warthman Associates , 1996
This book describes the code patterns that perform well on PowerPC processors. The book will be particularly helpful to compiler developers and application-code specialists who are already familiar with optimizing compiler technology.
(9581 views)
Understanding and Writing Compilers
by Richard Bornat - Middlesex University , 2008
This book attempts to explain and demystify the principles of compiler writing so that you can go out and build a working compiler of your own. There is enough detail in this book for you to build a compiler for quite a complicated language.
(6395 views)
Using and Porting the GNU Compiler Collection (GCC)
by Vincent Chung - Free Software Foundation, Inc. , 2001
This manual documents how to run, install and port the GNU compiler, as well as its new features. It corresponds to GCC version 3.0. Only the options for the C, Objective-C, and C++ compilers and those of the GCC core are discussed.
(7122 views)
GNU Compiler Collection (GCC) Internals
- Free Software Foundation , 2008
This manual documents the internals of the GNU compilers, including how to port them to new targets and some information about how to write front ends for new languages. It corresponds to the compilers (GCC) version 4.4.0.
(5596 views)
Project Oberon - The Design of an Operating System and Compiler
by Niklaus Wirth, Jürg Gutknecht , 2005
Here are the results of Project Oberon, which goal was to design an entire system from scratch. It gives advice on how a system might be built, and demonstrates how one was built. Program listings alone contain the ultimate explanations.
(10788 views)
Let's Build a Compiler
by Jack Crenshaw , 1995
A tutorial on the theory and practice of developing language parsers and compilers. It covers every aspect of compiler construction, programming language design, and building a working compiler. More theoretical aspects of the subject are ignored.
(7850 views)
An Introduction to Compilers
by Dirk Vermeir - Vrije Universiteit Brussel , 2009
Contents: Introduction; Lexical analysis; Parsing; Checking static semantics; Intermediate code generation; Optimization of intermediate code; Code generation; Introduction to x86 Assembler Programming under Linux; Mc: the Micro-x86 Compiler; etc.
(6126 views)
Compiler Construction using Flex and Bison
by Anthony A. Aaby - Walla Walla College , 2004
Guide to compiler construction using tools like Flex and Bison. Using these tools, you can focus on the concept of compiler without the hassle of building a compiler from scratch. You are required to be fluent in C programming.
(6942 views)
Compiler Construction
by Niklaus Wirth - Addison-Wesley Pub , 1996
This book has emerged from the author's lecture notes for an introductory course in compiler design at ETH Zürich. This book will try to explain why this subject is considered as important and relevant to computer science students in general.
(8314 views)
Basics of Compiler Design
by Torben Mogensen - Lulu.com , 2007
The book written for use in an introductory compiler course. It is intended to convey the general picture without going into extreme detail. It should give the students an understanding of how compilers work and the ability to make simple compilers.
(7615 views)
Parsing Techniques: A Practical Guide
by Dick Grune, Ceriel J. H. Jacobs - Ellis Horwood Ltd , 1998
This book treats parsing in great depth. It offers a clear and thorough discussion of different parsing techniques with their applications, including error recovery techniques. The text covers almost all parsing methods, not just the popular ones.
(10181 views)
The GENTLE Compiler Construction System
by Friedrich Wilhelm Schröer - R. Oldenbourg Verlag , 2005
This book presents Gentle, an integrated system for compiler writers. Gentle supports the description of compilers at a very high level and relieves users from the need to deal with implementation details, significantly increasing productivity.
(5449 views)
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text: "Jesse leaves the stage for maybe 90 seconds in WAITRESS. She's missed 2 shows in 3 months. "Questionable"? Give me a flipping break. She's one of the most dedicated performers working today. If you want to talk about "questionable" attendance, why not ask the lady at Studio 54 who's out often but still has time to perform at 54 Below?"Did you finally realize that she isn't your BFF?

subset: commoncrawl


text:
Entertainment briefs: 'Sondheim' show ending early
The CLO Cabaret production "Side by Side by Sondheim" will exit early to make way for the return of "Defending the Caveman."
The revue of Sondheim's music had been scheduled to play through Aug. 14. But when given the opportunity to open "Defending the Caveman" earlier, Pittsburgh Civic Light Opera administrators chose to reschedule.
"Side by Side by Sondheim will continue through July 14 at at the Cabaret at Theater Square, Downtown. CLO Cabaret has notified those with existing reservations and rescheduled them or offered refunds.
"Defending the Caveman" will now open Aug. 1 and run through Oct. 20.
Performances of either show are generally at 7:30 p.m. Wednesdays through Fridays, 2 and 8 p.m. Saturdays; 2 p.m. Sundays. Admission is $34.75 and $44.75.
Details: 412-456-6666 or pittsburghCLO.org
— Alice T. Carter
Checking out the local eagle
Before you watch fireworks on July 4, you can check out America's national bird, the bald eagle, at the Hays bald eagle nest.
Representatives of the Audubon Society of Western Pennsylvania will be on hand from 10 a.m. to 1 p.m. July 4 with spotting scopes and binoculars, to help you view the two adult bald eagles and the rare little eaglet that hatched in mid-April.
The nest stands along the Monongahela River. To get there, walk or bike from the Hot Metal Bridge in the South Side along the Great Allegheny Passage bike trail. Don't walk along the railroad or park in the Sandcastle parking lot, though; these areas are private property. Details: www.aswp.org
— Kellie Gormly


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Second law of thermodynamics
| The poetry of reality
|Extraordinary claims with
extraordinary evidence
|Hot from the
giants' shoulders
""Nothing in life is certain except death, taxes and the second law of thermodynamics.
|—Seth Lloyd
The second law of thermodynamics states that "the entropy of an isolated system does not decrease". This is often taken to mean that "disorder always increases" and is frequently misinterpreted. Another way of putting it is "an isolated system's ability to do work decreases over time". The second law provides the thermodynamic arrow of time in that one can tell the difference between the past and the future by looking at the amount of entropy in the closed system.
Explanation of terms[edit]
Thermodynamic systems[edit]
- Open system — Exchanges both matter and energy with its surroundings
- Closed system — Exchanges energy, but not matter, with its surroundings
- Isolated system — Exchanges neither energy nor matter with its surroundings
The Universe is an isolated system since it is a term to describe the entire spacetime continuum, including all of the energy stored in it. In reality, the Universe is regarded as the only true isolated system, as perfect isolation on a smaller scale is impossible. The Earth can be viewed as an approximately closed system, although it is open in reality.
Strictly speaking, entropy is the logarithm of the multiplicity of states, or the degree of dispersion of energy in a system. It is expressed by the equation Entropy = kB lnΩ, where kB is Boltzmann's constant and Ω is the multiplicity of the states.
A more commonly given definition is "degree of disorder in the system," and hence the Second Law of Thermodynamics is often explained as "systems become increasingly disordered." From the definition above, this is equivalent to saying that a system will tend to transition from less probable to more probable sets of states.
Actually entropy is a little more abstract and the second law of thermodynamics implies that the Universe will always become increasingly uniform; that is, heat (transfer of energy in a way other than work) will spread until the entire universe has the same temperature and energy level (between systems in thermal contact, heat always transfers from the system at a higher temperature to the one at a lower temperature until balance is achieved), and forces will continue to work until a universal balance has been achieved.
In other words, everything in an isolated system is seen to work towards attaining a state of equilibrium or balance. Once universal equilibrium is attained there will be no basis for any work to be sustained or to occur; ergo the forces in an isolated system will become sedentary and no work will be done.
The simple physical analogy commonly given, is that given a period of time, a room will become more disordered (stuff gets distributed evenly throughout the room instead of being concentrated in a neat stack) as long as a person lives in it but does no effort to clean it out.[1] In the physical world, all forms of energy are converted to thermal energy, and become more uniformly distributed among the Universe, until the universe becomes energetically uniform. In its final state the Universe will become one uniform space where no work can be done since energy cannot be "concentrated" by doing work. This state is called maximum entropy. When the universe has reached maximum entropy it is said to be completely "disordered" as there are no ordered patterns left and there is no way to ascertain information about the history of the universe.
In actuality, as opposed to being in a state of complete disorder upon achieving maximum entropy, the Universe has instead homogenized and become more uniform. In very simple terms, maximum entropy ≠ disorder, get it? It is on a basis similar to this that scientific educators have recognized that the disorder terminology, while simple and easy to comprehend, is an oversimplification at best, and a misleading false analogy at worst. As a result, disorder terminology has been largely phased out; most chemistry textbooks, for example, have removed (or at least heavily edited out) the disorder terminology.[2] Of utmost importance, entropy is an energetic phenomenon, and only tangentially has to do with the distribution of matter in a system.[3] (Statistically speaking, the molecules of a gas are unlikely to move to one side of a container without work being done on the gas. But doing work on the gas would increase the entropy of the universe, as the plunger, or whatever does the compression, would have to increase its entropy.)
The Second Law is a law of statistical mechanics, rather than a fundamental law of nature. As such, it is not entirely impossible to be violated; however, its violation is extremely unlikely. But because its violation is not impossible, only extremely unlikely, it turns out that over extremely long timeframes, a violation may eventually occur. For example, a classical system which exhibits the second law of thermodynamics over reasonable timespans, may nonetheless violate the law over times on the order of its Poincaré recurrence time — when Poincaré recurrence occurs, the entropy of the system will decrease to its original value. However, given the Poincaré recurrence time is going to be greatly longer than the age of the Universe so far, this is a purely theoretical consideration. Additionally, given any instance in which a macrostate decreases in entropy, there will be an astronomically large number of other instances of the same macrostate increasing in entropy. Also, the Second Law applies to large-scale systems; given two molecules, it is unlikely for the one with lower vibrational energy to impart some of its energy to one with higher, but unlike with large-scale systems, it remains a sizable possibility, and given the large number of molecules, it is guaranteed to happen occasionally.
Misapplication by creationists[edit]
The false analogy of entropy as disorder is used in a number of fields outside of science with varying success. Creationists have picked up on disorder terminology and attempted to apply the second law of thermodynamics as a refutation of evolution. The analogy would state that more complex life-forms could never evolve from simpler ones.
It seems obvious that this false analogy of a false analogy is incorrect. First, the Earth is not an isolated system — it receives a copious amount of incoming energy from the Sun. Second, evolution does not imply that life is becoming increasingly complex; it only says that natural selection allows genes to be passed on and different characteristics hence preserved.
It also is a corruption to believe life is always "more ordered" than inanimate objects. In fact, life does not violate the second law of thermodynamics in strict energetic sense. The energy of the sun is converted into chemical potential energy, which is converted to mechanical work or heat (the Earth is not an isolated system.) In each case, the energy transfer is inefficient, and some energy is dissipated as heat to the environment, leading to a dispersion of energy. In the same way, "ordered" snowflakes can form when the weather becomes cold but the entropy of the universe still increases.
Victor J. Stenger, a theoretical physicist, refuted this creationist claim:
""However, a transmitter and a receiver are two interacting systems. They are not individually isolated. So, the entropy lost by one system can be gained by the other. Or, equivalently, the information lost by one can be gained by the other. So a physical system, such as a biological organism or Earth itself, which gets energy from the sun, can become more ordered by purely natural processes.[4]
A quote in reference to chemistry education illustrates this point:
""One aspect of biological systems that intrigues students is the possibility of discovering violations of the well-known laws of thermodynamics and physical chemistry. It is easy to refute most of the examples suggested. A germinating seed or an embryo developing in a fertilized chicken egg are often naively cited as examples of isolated systems in which an increase in order, or decrease in entropy occurs spontaneously. It is evident, however, that respiration, assuming O2 is present, produces an increase in entropy in the form of heat, which more than compensates for the decrease in entropy that arises when the elements present in the seed or in the yolk of the egg are organized into tissues of the plant or animal. Indeed, neither germination nor embryonic development will occur in the absence of oxygen in the system in question.[5]
In reference to evolution, PZ Myers put it: "The second law of thermodynamics argument is one of the hoariest, silliest claims in the creationist collection. It's self-refuting. Point to the creationist: ask whether he was a baby once. Has he grown? Has he become larger and more complex? Isn't he standing there in violation of the second law himself? Demand that he immediately regress to a slimy puddle of mingled menses and semen."
Furthermore, Carl Sagan pointed out that if the second law of thermodynamics were applied to a god, then god would necessarily have to die.[6]
(Brief quiz about thermodynamics: How many generally recognized laws of thermodynamics are there? We know about the second law: Give the numbers for the other laws.[7])
Let us suppose that there actually were some process in nature which violated the second law of thermodynamics. Is that any reason to suppose that intelligent designers are responsible? The only intelligent designers that we have familiarity with, humans and other more-or-less intelligent animals, are as much subject to the second law of thermodynamics as are non-intelligent agents. Indeed, the laws of thermodynamics were discovered as limitations on what the clever engineers of the 19th century were able to design. Intelligent designers are not able to construct perpetual motion machines. Intelligent designers don't bypass the second law of thermodynamics.
(See also, The Simpsons: "Lisa! In this house we obey the laws of thermodynamics!")
Some young Earth creationists have invoked "hydrodynamic sorting" in Noah's flood to account for the organization of the fossil record. Thereby they implicitly acknowledge that an undirected mechanical process is capable of producing order from disorder, and contradict their naive version of the second law of thermodynamics.
Can entropy be reversed?[edit]
See also[edit]
- Laws of thermodynamics
- Maxwell's Demon — A Thought experiment designed around the possibility of violation of this law.
External links[edit]
- The Second Law of Thermodynamics by Frank L. Lambert, Professor Emeritus of Occidental College
- Christian Right Lobbies To Overturn Second Law Of Thermodynamics (The Onion)
- [MC Hawking — Entropy]
- Physics for Scientists & Engineers (6th edition) Raymond A. Serway & John W. Jewett, Jr.
- ↑ Note, however, that a clean room and a messy room with the same objects at the same temperature have the same entropy content, as physical changes do not significantly change the entropy content in a system.
- ↑ http://web.archive.org/web/20090729063233/http://www.entropysite.com/(archived from 29 July 2009)
- ↑ When confining matter to a smaller volume, there are fewer translational energy levels available to the system and hence a lower density of states for a system. It is the number of microstates of the energy quanta corresponding to a macrostate that is important in determining the entropy of the system, and hence the two are related. Note, however, that two gases separated by a barrier will indeed mix despite maintaining the same volume, and hence one can't separate entirely the distribution of matter from the distribution of energy.
- ↑ Victor J. Stenger, God and the Folly of Faith: The Incompatibility of Science and Religion, Amherst, NY: Prometheus Books, 2012 ISBN 1616145994, page 116
- ↑ Klein, J. J. "An Apparent Violation of Second Law of Thermodynamics in Biological Systems." J. Chem. Educ. 1979, 56(5), 314.
- ↑ The God Hypothesis atheistnexus.org
- ↑ Answers: There are four generally recognized laws: the zeroth, first, second, and third.


text:
Students research biodiesel fuel from different angles
"Everybody had fries, and I wondered what food service does with used cooking oil," says Wladkowski, an alumnus of the college who returned to teach in 1995 after earning his Ph.D. at Stanford. "I had heard there was a process to convert it into fuel, but I didn't know much about it."
Back in his office after that fateful lunch, Wladkowski found an abundance of information on the internet about converting used cooking oil into biodiesel fuel. He discovered that the chemical process is straight-forward if a bit messy and the equipment not terribly complicated. But it does require a ready source of used cooking oil.
"The brilliance of the process is that once the oil is chemically converted, it works in any diesel engine," Wladkowski says. "It is a classic example of recycling and has the other advantages of being more environmentally friendly, with better fuel efficiency, less emission and less wear-and-tear on the engine."
From the student standpoint, biodiesel fuel as a topic gave students a research focus that was practical and exciting – not simply an academic exercise. Graduating seniors Louis Lachman and Ken Coffey went right for it. Lachman, a Chemistry major from Woodstock, Md., researched the effects of different amounts of catalyst on the synthesis of biodiesel fuel using 10 gallons of unused canola oil purchased at a local retailer, since it was important his oil had no contaminants.
Coffey, an Environmental Policy and Science major from Walkersville, Md., not surprisingly looked at biodiesel fuel from the opposite view – the footprints it leaves behind. He wired his own apparatus that would help him measure engine values as the biodiesel fuel burned and bought an enormous Army diesel generator from a government surplus store. With the help of friends he restored the generator, parked behind the loading dock of McDaniel's science building, to working condition.
Lachman helped him produce about 40 gallons of biodiesel fuel from used cooking oil from Harry's restaurant on Westminster's Main Street. Ultimately, Coffey explored the running characteristics of the fuel, looking at exhaust gas temperatures and make-up, fuel consumption and the like.
Although the projects served his students well – and his own knowledge of biodiesel fuel has grown exponentially – Wladkowski still wonders what the project could be if he had a ready supply of used cooking oil. With conversion costs at about 50 cents a gallon (and one gallon of used oil produces a gallon and a half of biodiesel fuel), why couldn't they produce biodiesel fuel to run the college vehicles and other machinery?
Currently, McDaniel doesn't have a lot of diesel vehicles, but Wladkowski sees that as a minor problem, saying that over time diesel vehicles could replace gas-burning vehicles. He estimates it would take about 100 gallons of biodiesel fuel a month to power all the vehicles.
The bigger problem is a ready source of used cooking oil. And that's something he's working on with the college's food service, which contracts with a company to haul away the oil.
"This is a great way for students to learn science," he says. "And that's what we're about here."


text: Woman's Research Researching ways to improve the health of women and infants. Woman's Research conducts clinical and molecular biology/genetic research, and collaborates with institutions across the U.S. All clinical research studies are submitted to Woman's Research and Development Council. Studies involving human subjects are referred to the Woman's Hospital Foundation Institutional Review Board for review. Learn if you can be a part of our mission by participating in the following studies. Polycystic Ovarian Syndrome New direction in treatment for women with PCOS Woman's is launching a new 24-week study for women who have PCOS and impaired carbohydrate metabolism. The study will test the success of new medicines that have been found to improve abnormal glucose metabolism and reduce body weight. We are looking for 125 women who meet the following criteria: 18-45 years old with PCOS Must have a body mass index of 30-45 Have less than nine periods a year Nonsmoker Not pregnant or breastfeeding Participants will be compensated for their time. If you are interested or have questions, please call 225-231-5296. Post Gestational Diabetes Studies Better Rx for Gestational Diabetes Mellitus (GDM) Study explores why one out of every three women with gestational diabetes will battle "pre-diabetes" after her baby is born. This means that blood glucose levels are higher than normal. People with pre-diabetes are at a high risk of developing diabetes. Woman's BetteRX Moms study will compare the effectiveness of different oral medicines in treating this condition. BetteRX Moms must meet the following criteria: English-speaking women ages 18-42, had gestational diabetes during their last pregnancy, gave birth less than a year ago and diagnosed as pre-diabetic by an oral glucose (sugar) tolerance test. Participants will receive the following at no charge: A personalized diet and exercise plan, physician office visits, lab testing and an oral medication for 16 weeks (randomly assigned medications include Sitagliptin plus Metformin (Janumet), Metformin or a placebo.) Participants will also be compensated for their time. Study to Prevent Diabetes in Post-Pregnancy, Overweight Women with History of Gestational Diabetes will focus on preventing the onset of diabetes in overweight women with a history of gestational diabetes who delivered less than a year ago. In a double-blind placebo trial, for the next two years, Woman's will monitor 150 women in order to determine the effectiveness of two drug combinations in stabilizing sugar and insulin levels and promoting weight loss. The medications are Metformin and Metformin in combination with Liraglutide, a long-acting glucagon-like peptide 1 (GLP-1) derivative administered once daily. Combined Liraglutide and Metformin Therapy in Women with Previous Gestational Diabetes Mellitus will study overweight women who were diagnosed with GDM in their last pregnancy, have not returned to normal metabolic function, and remain overweight with diagnosed insulin problems. Participants must have delivered infants at Woman's Hospital and had GDM within the past year, be 18-45 years old, and meet all additional study requirements. Participants will be compensated for their time in addition to receiving free medication, clinic visits with the physician, and testing. For more information, patients may contact Woman's Research at 225-231-5275 or email us. Pregnancy & Nutrition Studies LAMBS: Are you pregnant? If so, you may be eligible to participate in the LA Moms and Babies Study (LAMBS) for nutrition and growth. This research study evaluates how diet during pregnancy can benefit pregnancy and pregnancy outcome, such as your baby's weight. Information gained from LAMBS will help us make the best nutrition and diet recommendations to pregnant women and women of child bearing ages. You may be eligible to participate if you are : Pregnant Overweight 18-35 years old Benefits to participants: General nutrition guidelines provided during study Summary of infant's growth during first year of life Qualified study participants will earn up to $575 over the course of approximately 80 weeks To learn more, call 225-231-5275 or email us. Gynecologic Cancer Clinical Trials Woman's actively participates in ongoing clinical cancer research. To learn about the most recent gynecologic cancer studies, and find out if you are a candidate, please contact Ashley Marks, BSN, RN, 225-924-8215. Breast Cancer Clinical Trials The medical staff at Woman's Hospital supports breast cancer clinical trial research in coordination with Mary Bird Perkins Cancer Center in Baton Rouge. For a complete list of current clinical trials, visit Mary Bird Perkins >> If you are interested in participating in a clinical trial, always contact your physician to discuss options that are available to you. For further information or questions about participation in clinical trials, you may contact a clinical research representative at 225-215-1353, or email us.


text: BMG LABTECH has become a world leader in microplate reading systems due to continuous integration of new and unique technology. Much of our newest technology has been implemented based on our customers' suggestions. In essence, it is our customers that drive innovation and advancement of our microplate readers. Some of our technological advancements include:


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SHANGHAI, Oct 10 (Reuters) - China's central bank on Monday set the midpoint for the yuan currency weaker than the psychological 6.7 yuan per dollar level after a week-long national holiday during which offshore yuan touched nine-month lows against the dollar.
The People's Bank of China put the midpoint at 6.7008 yuan per dollar. It was the weakest midpoint since September 2010. The currency is allowed to trade in a band of 2 percent on either side of the midpoint, which is set each day.
The spot rate quickly followed suit, dipping below 6.7 for the first time since July.
On Friday the offshore yuan slumped to its lowest rate against the dollar since Jan. 7.
In the weeks before onshore markets closed for the National Day holiday from Oct. 1-9 the spot rate flirted with 6.7. The last close was at 6.6745.
On Oct. 1 the yuan was officially added to the basket of currencies that determines the exchange rate of the International Monetary Fund's synthetic reserve currency, the Special Drawing Right, or SDR. (Reporting by John Ruwitch and Winni Zhou; Editing by Eric Meijer)


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Hey there, time traveller!
This article was published 22/9/2010 (2526 days ago), so information in it may no longer be current.
They say that as you get older the past looks increasingly better. I wonder if that is the case with politics?
It seems that every decade voters bemoan the state of politics and politicians, claiming yesteryear featured stalwart leaders who bestrode Parliament with rhetoric and integrity in a manner that they do no more.
Is it really so much worse now? I think it depends on what you compare it with. I wasn't around when Abraham Lincoln was in the White House nor when Winston Churchill led Britain at war. I was in Canada for the last of the Trudeau administrations but by then the bloom had departed the rose.
Jean Chrétien was damaged by the sponsorship scandal. Paul Martin, who was so impressive as finance minister, failed to grasp the mantle of the prime minister's job with the same firmness and paid the price. Stephen Harper still seems stiff -- his singing of Beatles songs notwithstanding -- and he is oddly clumsy in his choice of the issues he fights on. But is Harper really less admirable than John Diefenbaker or John A. Macdonald, who was accused of taking bribes over the construction of the trans-Canada railway?
Our collective ennui with politicians has as much to do with the times as it has with the actions of the politicians or the practices of Parliament.
If the members of the House of Commons are smart they will agree in the present session to amend question period so that it resembles less of a bar-room argument and more of a quest for answers and a probing of responsibility. Having a single day to question the prime minister instead of parading him all the time would be one notable change that would remove some of the constant barracking and point-scoring that plays to television today.
But it is not question period or the sight of politicians saying one thing and voting another, as some have done over the long-gun registry, that has brought our politicians and politics into such disrepute. Politicians have always changed their minds.
Some of the decline in our opinion of our leaders has to do with the constant glare of media attention. In John A. Macdonald's time, it was possible for leaders to appear more dignified and above the crowd. In the world of the Internet that is simply impossible.
But the Internet and other media don't, on their own, explain why politics and politicians are so despised, nor why, occasionally, some rise above it. Take the last American election campaign, for example. Barack Obama rose above the fray to appear as a fresh, charismatic voice with a new plan to reshape politics in the U.S.
Today, according to Gallup polls, Obama's approval rating is tracking about the same as president Bill Clinton's and much worse than president George W. Bush's at a similar juncture in their terms in office. Therein lies a clue. Bush's approval rating shot up after the events of 9/11. There was a similar leap in the popularity of prime minister Margaret Thatcher after her decision to sail the British fleet to the Falkland Islands to rid them of the Argentine invaders.
Churchill is still admired because of the scale of the task at hand -- winning the Second World War. Bush, after a shaky early response, famously stood at Ground Zero with his megaphone and appeared as the leader Americans needed. Franklin Roosevelt combated the Great Depression and so on.
It was the times that shaped our views of the leaders. President John F. Kennedy had the Cuban missile crisis; Trudeau emerged when North America was going through the biggest upheaval in social mores in a century. His statement, "There's no place for the state in the bedrooms of the nation," spoke to a generation. Macdonald forged a country.
You might think that the financial crisis of the last two years and the resulting recession would have created a similar Big Picture opportunity. But in Canada the recession has been relatively mild and in the United States, Obama has been unable to convince his electorate that he has the answers.
Our view of politics and politicians may be at a low point because issues like the gun registry and the census may be important but they pale in comparison with 9/11 and the Cold War. Abraham Lincoln had civil war and slavery to deal with. Our leaders have no such challenges and no such issues.
Nicholas Hirst is CEO of Winnipeg-based television and film producer Original Pictures Inc.


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Book stores. Porn emporiums. Blockbuster Video. 10 Years. These are just a few of the things that the internet has made relatively pointless, but they all have their charms. We can buy our books, jerk off mightily, watch a movie and keep in touch with our high school friends just fine without leaving the house anymore, so all those stores – and the new film about a contemporary high school reunion – feel like nostalgic relics of a bygone era. Granted, that era's just ten years gone, but hey, if I have to feel old then so do you.
American Reunion couldn't get away with its ugliness and judgmental attitudes, but it got away with the high school reunion conceit because audiences were familiar with the characters and hadn't seen them together on screen in years. 10 Years tries to get away with its concept by flooding the screen with recognizable faces in roles so formulaic they feel like you already know them. Channing Tatum is about to get engaged, but first has to come to terms with his high school sweetheart, played by Rosario Dawson. Justin Long and Max Minghella are both jealous of each other's success – one in business, the other in marriage – but are each trying to make time with the girl who got away, played by Lynn Collins. Oscar Isaac is the class celebrity, who's back in town for mysterious reasons having to do with his hit single.
It's a testament to the cast – which also includes Ron Livingston, Ari Graynor, Aubrey Plaza and Chris Pratt – that 10 Years plays as well as it does. The plot contrivances are familiar, the jokes largely milquetoast, and the life lessons are obvious to the casual viewer. People move on, people get closer together, and occasionally it's harmless and sweet. And occasionally it's very creepy. Late in the film, Long and Minghella decide to follow Lynn Collins home, reacting to their perceived rejection the same way you'd expect them to in a Nikkatsu Roman movie. Sure, their ultimate goal is to toilet paper her house, but lurking in the shadows and whispering about the cathartic vengeance they yearn to unleash gives the impression that something infinitely darker was on someone's mind, at least on a subconscious level. Eventually it flips around and tugs at the heartstrings, so… that's good, but the creepiness lingers long afterwards.
There are isolated moments of memorable character work and mild life-affirming joy, but with a story spread this thin (and one that was pretty thin to begin with) 10 Years never has enough substance to warrant its own existence. If you want to see Channing Tatum being charming, you have every other film he's made. If you want to see a character play their original song to a female listener in the audience who comes to a realization, you have Nashville. If you want to see wiggers making good… actually, this might be one to watch. 10 Years is nothing new, and nothing terribly special, but it's well intentioned and not a chore to sit through. I expect more from my sincere nostalgic dramas, but if you don't, it gets a lot worse than 10 Years.


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First few days
Cancun and Isla Mujeres
16.06.2008 - 18.06.2008
View Mexico, Central and South America on ajthalita's travel map.
So we get on the plane all ready to go, and we´re about 100 feet from the runway... Then the captain notifies us of a rerouting do to weather with a, ¨We´ll be on our way in a few.¨ An hour and a half later we take off and land in Cancun at about 4:30 pm. After the million and one touts advertising cheap 40 dollar taxi rides or 20 dollar shuttles, we realized that all the airport workers must have a way home every day. So we asked around til we found the public bus for $3.50. That took us to downtown, where we proceded to fumble around until we found our place, Hostel Kankun, the infamous ¨cheapest place in Cancun¨. We checked in, dropped our bags, and headed out to find some food. We saw a little seafood place called Pescaditos, with plenty of happy faces, so we knew it had to be good. After some fish sticks (mexican style), chips, and some cold brew, we went back to the hotel to wash the day´s grime away and fall asleep. Thalita was out by 8:30 pm which left me lying awake with no tv, just listening to the fan, and wishing it would go faster.
The next morning we make our way by bus to Puerto Juarez, to take the ferry to Isla Mujeres. We find a nice hotel for relatively cheap, and then made our way to the beach.
Stupid, white, and stubborn would be great ways to describe my first day at the beach with sunblock only applied to my face. What a tard. Two hours later i´m done, roasted like a christmas turkey. Thalita on the other hand, with her Brazilian heritage, managed to squeek by the red, and straight to golden brown. Puta.
After this, back to the hotel for a cold shower, some lotion, and a siesta. We went back out about 6 to eat something and then strolled around for a bit. Then more and more lotion on sunburn. That leads us to today, and being inside on the internet.


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I'm enjoying a dig back through the archives of fashionably GEEK (pub suit and bigfoot v. unicorn pictured). It's like digging through the Gadzooks warehouse.
nerdy threads
Sell your hair at the hair museum
My Mom recently took a little side trip with her sisters to one of the weirder museums that the midwest has to offer. Leila's Hair Museum in Independance, Missouri is probably the world's only hair museum, acting as the headquarters for the Victorian Hairwork Society. The museum sports a large collection of hair jewelry and samples dating back to 1725. Hair jewelry really caught on during Victorian times when it was regularly used to honor a dead relative or loved one as part of the mourning process.
But what say you want to get started on making some of your own hair medallions, rings, and broaches but you don't want to part with your curly locks. We'll just a click away are several pages full of people offering their hair up for sale. I guess there's nothing inherently creepy about this but the pages of pictures with oddly obscured faces and tons of long flowing hair kinda wigs me out (pun intended).
But nevertheless this place sure is going on my list for the grand mid-west museum field trip.


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Two sisters held against their will for a week in a South Tucson motel room were drugged, beaten and raped by their captor, according to court documents obtained Tuesday.
Their alleged captor, Rene Francisco "Spanky" Canez, 35, was booked into the Pima County jail Oct. 15 and is being held on $500,000 bond. He is facing 11 charges including kidnapping, sexual assault, aggravated assault, armed robbery, administering narcotics and prohibited possession of a gun.
At about 5 p.m. Oct. 9, the two sisters, ages 22 and 26, went to Canez's room at El Camino Motel, 297 E. Benson Highway near South Fourth Avenue, to buy marijuana for personal use, according to an interim complaint filed with the Pima County Justice Court. The women had bought marijuana from Canez previously.
He invited the sisters into his motel room but would not allow them to leave.
"Canez used a variety of weapons" to threaten and assault both women, including a handgun, knives, a Taser and a curtain rod, the complaint stated. He also beat them, kept them naked, injected the women with heroin, forced them to smoke heroin, starved them and stole $200 from them.
"Over the course of almost seven days Canez sexually assaulted" the sisters repeatedly, forced them to perform sex acts on each other, recorded the assaults with his camera phone and invited others into the motel room to watch the sexual assaults, the complaint stated.
The women "were in constant fear of being killed, reinforced by Canez's threats and intimidation," the complaint stated. "The women did not eat for seven days while being held captive."
Early on the morning of Oct. 15, a woman unrelated to the two captives, went to Canez's motel room looking for her own sister, the complaint stated.
"While standing at the open door, the witness observed both victims sitting on a mattress inside the room, and they appeared very scared and beaten up," the complaint stated. "Both victims kept gesturing to her to help them."
That's when Canez forced the third woman into the room, held her against her will for 15 to 20 minutes and made her "smoke heroin from a piece of foil."
When the three women saw an opportunity to escape, they ran out and flagged down a taxi. The sisters got home and called police, the complaint said.
Canez previously served more than a year in prison for a drug offense, records show.


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|January 8, 2014
08:30 AM to 03:30 PM
|Forsyth County Professional Development Center, 1120 Dahlonega Highway, Cumming, GA 30040
|Forsyth County Professional Development Center
1120 Dahlonega Highway
Cumming, GA 30040
|No Cost
|Discovery Education, the global leader in standards-based digital content for K-12, is hosting a series of professional development events at no cost supporting Atlanta-area educators grappling with the implementation of the Common Core State Standards. During Discovery Education's Common Core Academies, teachers and administrators will learn practical instructional strategies for using digital media and other educational technologies they can immediately implement supporting the integration of the Common Core State Standards into classroom instruction. Led by an expert and thought leader in the world of education with decades of experience in professional development, the Academies will cover the following: • Leadership Strategies to Support Digital Literacy and the Common Core (Wednesday, Jan. 8): This session will offer practical leadership approaches for administrators that will help support teachers in their implementation of digital literacy instruction and assessment. • Teaching and Assessing Common Core Math in a Digital World (Thursday, Jan. 9): An exploration of the Standards for Mathematical Practice and their successful implementation with assessment strategies, this session will support the development of mathematically proficient students. • Literacy and the Common Core in a Digital World (Friday, Jan. 10): This session offers English Language Arts (ELA) instruction and assessment strategies to support the development of digitally literate students to prepare them for college, careers, and citizenship.


text:
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JERUSALEM (Jul. 29)
Prime Minister Levi Eshkol's office denied categorically here today reports in the foreign press claiming that Mr. Eshkol is contemplating a trip to the Soviet Union to meet with Soviet Premier Nikita S. Khrushchev.
The reports, as received here, stated that Mr. Eshkol would like to follow his trips, made this summer, to Washington and Paris, where he had met with President Johnson and President de Gaulle, with a similar summit visit to Moscow. According to the reports, Yosef Tekoah, Israel Ambassador to the USSR, was carrying on conversations with the Soviet Foreign Ministry in Moscow with a view to have Mr. Khrushchev extend an official invitation to Premier Eshkol.
Mr. Eshkol's office said today those reports are "incorrect." It was pointed out that, in an address before the Israel Parliament last week, Mr. Eshkol said, among other things, that he would welcome an invitation to meet Mr. Khrushchev.


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NEW YORK (Apr. 23)
Israelis involved with Holocaust research are becoming concerned about the current tendency to go too far with "Americanizing the Holocaust" — making it accessible to the American experience — by "packaging" it within a list of familiar evils, thus robbing it of its uniqueness in human history.
Characteristic of "going too far" in "Americanizing the Holocaust" are statements such as "the Holocaust shows what prejudice, discrimination and intolerance can lead to" and "the Holocaust is part of the long history of man's inhumanity to man," which make it possible to avoid confronting its quintessential difference and the basic questions it raises.
This view was expressed by Yitzhak Mais, director of Yad Vashem's Museum, in an interview with the Jewish Telegraphic Agency here. American-born Mais, who has been involved with Holocaust studies since his aliya in 1973, recently visited the U.S. where he served as a consultant to the United Jewish Appeal on its Auschwitz exhibit, now being shown in Los Angeles and is touring the country.
To Mais, the uniqueness of the Holocaust lies in "the singling out of Jews to be killed because they were considered racially dangerous." The Nazi policy of wiping out all the people of one group without exception — "just because they existed they had to be killed" — is what makes it significant and fundamentally different from the many other inhumane events in world history, he said.
The Holocaust, Mais continued, needs to be presented both as a uniquely Jewish event and as one having universal significance. Making it accessible and relevant to the American reality is valid. If it is inaccessible, "one can't learn from it — it remains in an archive. If it's placed on some inapproachable metaphysical pedestal" the questions it raises as an event that happened on this earth cannot be confronted.
However, Mais said, there are authentic and unauthentic ways of making the Holocaust accessible. An authentic way of "Americanizing the Holocaust" is to deal with the American participation in the event: showing the role of American liberators, bringing in the experience of survivors, discussing what the U.S. government did and did not do.
Unauthentic ways in which "Americanization of the Holocaust" is carried too far involve placing it on a list of the horrors of human experience. "If you don't acknowledge the Holocaust's uniqueness as the watershed event in history that it is, you are dealing with it and avoiding it at the same time," he said.
Avoiding the Holocaust eliminates the necessity to confront the philosophical assumptions it calls into question such as the inherent goodness of people, the belief in progress, the value of education in forming good character, and the superiority of Western civilization.
Early post-war ways of avoiding the Holocaust involved seeing it as an aberration, an idea that still exists in the popular mind, said Mais Statements such as "the Nazis were insane" and "Germans were brainwashed" allowed people to "pay lip service to the Holocaust but to avoid confronting the basic fact that good husbands and good fathers carried it out."
The Eichmann Trial of 1961, after which Hannah Arendt wrote of "the banality of evil," gave impetus to serious historical research. But it was the period of the late 1960's that saw a real change in the Holocaust consciousness of American Jews.
"This was a time of ethnic pride and one when questioning and protest were accepted," Mais said. Feeling permission to question the establishment on civil rights and Vietnam, American Jews came to feel they could also question the establishment about the Holocaust. The Six-Day War of 1967, replete as it was with Holocaust analogies, was also an important factor.
But what finally got the Holocaust into American consciousness, he said, was the miniseries of that name which aired on U.S. television in 1978. Even with all its problems, 220 million Americans "came to terms with the word Holocaust."
Because it would not have been aired had receptivity not been anticipated, the series was an important "signpost," he said.
While Israelis had long hoped the Holocaust would penetrate American consciousness, they are concerned about its being trivialized and misused. "We can't be blind to the Holocaust or be blinded by it," Mais said. One instance of being blinded by it occurs when people say, "You have to be Jewish because of what the Nazis did to the Jews." Here everything is "seen through the prism of the Holocaust and it is overemphasized to the point of becoming a surrogate Jewish identity or religion."
Another instance of being "blinded" by the Holocaust occurs when people say, "Israel has the right to exist because of the Holocaust." This "obliterates Zionism and its tangible expression," ignoring the fact that Jews have a right to their own country and worked for it in the 1890's, in the 1920's and 1930's, he told JTA.
Using the Holocaust to legitimize Israel makes Zionism appear to be a post-Holocaust response and phenomenon, "and if so, where did the infrastructure that allowed the survivors to be absorbed come from?" It is also ideologically dangerous, Mais continued, because Arab propagandists can and do argue that "Europe spit the Jews up and we have to pay the bill."
However, he said, there is a direct historical connection between the Holocaust ending in 1945 and Israel's creation in 1948 in that the need for a refuge for 300,000 DP's the world would not accept eventually led to the UN partition vote of 1947.
Furthermore, "one cannot understand Israel without understanding the Holocaust," Mais said. "It's part of our collective memory." Israelis share the consensus that Jews cannot afford to be in a situation of "hopelessness, helplessness and powerlessness" and that "there's only one country in the world that puts Jewish survival as its number one priority."
This is reinforced, said Mais, when you walk out of Yad Vashem. "You walk out of the building, out of the darkness, and you see the sun. You see Israeli soldiers and you walk into the sunlight of Jerusalem."


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Synthetic peptide conjugated to KLH derived from within residues 50 to the C-terminus of Mouse beta 2 Microglobulin.
Our Abpromise guarantee covers the use of ab87483 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|Use a concentration of 5 µg/ml.
|Use a concentration of 1 µg/ml. Detects a band of approximately 13 kDa (predicted molecular weight: 13 kDa).
Immunohistochemical analysis of formaldehyde-fixed paraffin-embedded murine pancreatic tissue sections, labelling beta 2 microglobulin antibody with ab87483 at a dilution of 1/80 incubated for 16 hours at 4°C in 5% BSA diluent. Heat mediated antigen retrival was with 10mM sodium citrate at pH 6.0. Blocking was with 5% serum incubated for 30 minutes at 20°C. Secondary was a biotinated goat anti-rabbit polyclonal biotin conjugate at 1/200.
ab87483 stained MEF1 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab87483 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.
ab87483 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"


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" Type: Ready Meals "
I try to cook most of my meals from scratch and often like to try and avoid ready meals as some of the varieties are very heavy on calories, fat and salt. However there are some occasions when I just want something quick, without using up my recommended daily allowance of calories, fat and salt and this is where Sainsbury's Basics Beef Lasagne comes in handy!
I first came across this ready meal in the frozen section when it was selling for 24p; I was quite surprised by how cheap it was as it was not on offer. It was selling for 24p for quite a few months in my local Sainsbury's before the price was raised to 76p. Nevertheless at 76p, it is still a bargain as it is pretty filling with some vegetables or salad at the side.
On first appearance, the packaging in white and orange symbolising the Sainsbury's Basics brand. It states on the pack that it is 283 calories, 7.0g of fat and 1.5g of salt for the entire lasagne. Whilst the calories, fat, saturated fat and sugar is under the green traffic light labelling, the salt content is under amber. However at 1.5g of salt for the packet, it is much lower than other ready meals.
As you remove the lasagne from the packet, you can see that it is in a black plastic tray with a film lid and you can see some of the tomato sauce around the edges of the pasta sheet. On the top layer, there is a tiny sprinkling of grated cheese. Although frozen, it can be microwaved or oven cooked without defrosting. I usually pierce the film lid and microwave it for 10-12 minutes on the highest category as I like the lasagne to be quite crispy. However the instructions recommend cooking it for around 8 minutes, but at this stage I find the sauce to be too watery still.
When it is halfway through microwaving, an appetizing aroma of lasagne always lingers from the kitchen. You can also see that the grated cheese has melted after it comes out of the microwave. I like to scoop the lasagne out of the tray onto a plate and serve with either salad or vegetables and often sprinkle with chilli flakes or pepper.
On first taste of the lasagne, you can taste a subtle hint of cheese, which compliments the mild tomato sauce. The pasta is well cooked - it is not too hard nor too soft and the white sauce is creamy and smooth. My only fault with this product, is the fact that there is not enough meaty pieces, however for the price I cannot complain. Overall the flavours compliment each other really well and though you may get hungry soon after if you ate this alone, it is filling with vegetables or salad on the side.
I would definitely keep this as a staple for times when I don't have time to cook; the fact it is reasonable in calories, fat and salt makes it a winner, as well as the great price! Though nothing beats home made lasagne.
This is one of Sainsburys basics range. The beef lasagne is a frozen ready meal. The pack is 340g and contains 283 calories. As this is a basic product there is not a huge amount of pasta or beef in here but it is quite tasty.
I went shopping in Sainsburys and saw this product in the freezer. The price on the ticket was 24p. At first I thought this must have been on special offer but it was not, this is the normal price! I have since bought around 5 of these and I can't believe that this only costs 24p!
As it is a Sainsburys basic product there is not a lot of product there, compared to other ready meal lasagnes which contain over 400g of product. However, if you add some vegetables and chips to this it should be enough for your meal.
It tastes really delicious. The sauce is realy tomatoey, the pasta nice and soft and the beef not grissly or bumpy like you can get in some cheaper products. There is no way you would guess this is a basics product. The only thing that could make this better would be to make it a bit larger. I suppose at 24p you could buy two for your meal...but that's taking it a bit to far!
I got this Lasagne on my way to work on Sunday for something quick to have for lunch and I saw this in the freezer section, I also noticed a meat lasagne, as apose to the beef one, which is slightly more expensive but after looking on the Sainsbury's website I also noticed it has a higher meat content and the beef lasagne did me nicely for a light lunch.
Price: This lasagne is only 24p for 340g! The meat one is 75p for 300g, so the Beef Lasagne is really good in comparison and well worth the money. Sainsbury's also make a Meat Lasagne for 4 which costs £2.98 which is also really good value.
Packaging: The usual Basic's packaging applies, white and orange, and like many Basic's products a photo of the Lasagne is on the packaging surround by a drawn on plate and lemon wedge. Unlike many ready meals where you can remove the sleeve to have a look at the meal inside Basic's Beef Lasagne is just in a box, but I thought I'd risk it seen as I'd always been pleased with Basic's in the past and it really in very cheap.
Cooking Instructions: This product only contained instructions for the microwave which is unusual but how I wanted to cook it anyway so I wasn't too bothered. You simply pierce the film lid and cook it at full power for 5 minutes. You then take it out and let it stand for a minute, put it back in and re- heat for another 4 minutes, it does get hot, the plastic especially so make sure you use a tea towel to get it out and leave it for another minute before eating.
Taste: I wasn't expecting much for the 24p I paid, I was surprised though, it was fairly meaty and the sauce on top was nice and creamy. I did put my own cheese on the top but I usually always do this with ready meal lasagne's anyway. Now I aren't going to pretend it tastes as good as home made, it doesn't but I wouldn't expect it to. It's a really good lasagne though, the bolegnese sauce is tomatoey and meaty and it all works really well together. The pasta was the only disappointment it has become abit crisp and hard, it didn't ruin the dish though and it was just the right size for a quick lunch, served with salad and some garlic bread this would make a nice main meal.
Calories: 283kcal
Fat 7g
Sat Fat 3.7g
Salt 1.53g
I think this is quite good overall, especially the calories, it means you don't have to worry if you decide to put a few chips with it to fill you up and it isn't too calorific to have for lunch.
Overall: I really would recommend this Sainsbury's Basic's Beef Lasagne, it's 24p price tag is the main selling point for me, along with the ease of cooking and great taste. However, it was let down by the pasta but I think this could be overcome by cooking it for less time, but as I followed the instructions and the pasta is a main componant of the dish it has to lose a star.
I love a bargain, and as this Lasagne was under a pound,so i considerer it as one. It was the quick and easy option for me, as i was going to be busy, and fancied something cheesy...
You only had to pop this in the microwave[ for 5 mins or so i think] and stir ad shake it when it tells you to. It was in a plastic container, with a sealed plastic cling film type lid. The slid of cardboard across the tub told you about the product and clearly showed that it was Lasagne. The coulor were not anything special, but at the end of the day, this is the basic range, and basic IS basic!!It clearly stated most of the info i need to know on the box.
The Lasagne was surprising not to bad, the pasta layers were cooked quiet well and where chewy, but quiet had to cut up. The meat, there wasn't much of this, but it was queit nice, apart from some small pieces around the edges of the tube which were only slighty over done, and again they were chewy. The sauce i enjoyed- there was plenty of it and was creamy and the thickness was about right.
The value for money was very good, and i would probably have it again. well done basic Sainsburys, you amaze me again!!!
I love nothing more than buying some bargains in my local Sainsbury's and I recently found a 'Basics Lasagne for just 17p (usual price 75p) and for this I received a 300g portion which is ample as a decent sized lunch. I have had one of these for dinner before and just had some nice garlic bread with mine.
This lasagne is provided in a plastic tray with no frills and the top is sealed with clear cellophane to keep everything in and there is a cardboard seal over the top which contains all the usual information, nutritional information, ingredients etc and everything about this product shows that its cheap but for under £1 I wouldn't expect anything more!
This lasagne is like any other meat lasagne I have purchased in the past and is made up of layers of beef mince in a Bolognese style sauce and layers of lasagne sheets and then the whole thing is topped with a béchamel sauce and I usually top mine off with some extra mature cheddar as it brings a lovely crispy top to this dish.
The meat is fairly well chopped up and in a nice, rich ragu sauce. The béchamel sauce is quite thick and has a fairly creamy texture to it. The layers of pasta are quite chewy but still fairly tasty. The whole dish works well together and what I do is just cook mine in the microwave (6-7 minutes with one minute standing time halfway through and at the end) and then once its done I mix the whole thing up so that all the creamy béchamel sauce mixes with the massive amount of mince and then there is a nice mix of everything.
Per 300g meal there are 286 calories, 5.2g sugar, 11.2g fat 4.6g saturated fat, 3.5g fibre and 1.51g salt so even if you had this as your lunch it could comfortable fit in to part of a healthy diet.
Overall this was quite a nice meal and was far tastier than I expected it to be. Obviously I was very please with the 17p I paid but I would also be happy to pay 75p for this as I think this is fantastic value and the portion size would suit a little one at teatime but just be cautious of the salt. 5/5 from me as the taste was lovely and this was the ideal portion for lunch.


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Jorge Valdes scored two goals as Cedar Shoals topped rival Clarke Central 3-1 late Saturday night.
Alex Reyes scored the Jaguars' other goal and Hex Gomez, Junior Zarco and Alex Reyes each added an assist.
Goalkeeper Josue Ruiz made 10 saves for the Jaguars (4-5-3), who will next travel to Winder-Barrow on Tuesday.


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We use cutting-edge technology to rebalance health
Emotional response is often rooted in biological imbalance
You can find us right across from the iconic Michigan Stadium!
Specializing in holistic medicine for children and adults
Using advanced testing, we can pinpoint where the problem lies
This website and all content and materials included on this website, are for informational purposes only. All information, text, graphics, illustrations, photos, video, and audio are protected under U.S. and international copyright laws and are the exclusive property of Dr. Tony L. Boggess. All written, audio, and video contents of this website are based primarily upon the opinions of Dr. Tony L. Boggess and Natural Balance Wellness Medical Clinic clinicians unless otherwise noted. Individual articles, audio, video contents are based upon the opinions of the respective author, who retains copyright as marked.
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The Players Championship's annual Military Appreciation Day on the Wednesday before tournament play begins has become a much-anticipated highlight of the week's festivities.
Country music star Jake Owen will headline this year's concert on May 7 on the TPC Sawgrass Clubhouse lawn. The concert wraps up a day of activities and programs to celebrate the men and women of the Armed Forces.
The Academy of Country Music's top new male vocalist of 2009, Owen has had four consecutive No. 1 singles since 2011.
"Performing for the military is always a true honor," Owen said in a statement from The Players. "I admire what these men and women do to serve our country, and I can't wait to show my support."
Along with the concert, The Players will recognize active duty, retired and reserve military personnel by allowing them and their dependents complimentary admission to the tournament all week. Military members interested in receiving complimentary admission to the tournament should go to PGATour.com/ThePlayers and click on the ticket link for instructions, as the process has changed from previous years.
Non-career military veterans are eligible for discounted tickets to the tournament. That information can also be found at PGATour.com/ThePlayers.
Copyright 2014 by News4Jax.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Gwen Stefani Is Obstructing Her (Probably Pregnant) Stomach
Posted by Photo Boy
Speculating on whether a woman's pregnant or not might be the worst thing for anyone to do, which is exactly why it's the subject of approximately 76.42% of our posts. So, here's Gwen Stefani suspiciously wearing loose, flowing clothing and using things like purses and large automobiles to hide her clearly gestating womb. I mean seriously, Gwen, wrap shawls and the old large purse trick? It's obvious you and a boy held hands in your bedroom with the door closed, so now you'll never go to college and your life is ruined. Someone should have paid more attention in vacation bible study.
Photo: Fame/Flynet, Splash News


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- Foam soles
- Moisture management footbed
- Rubber straps
- Camo fabric on straps
- Stud and crystals embellishments on straps
- Camo print on sandalf ootbed
Get your country style on in these Justin Jemma Camo Sandals. Bling and camo are a country girl's must have. Just in time for summer, Justin brings you these fun and fashionable sandals. Slip these on between your toes and dress up your whole outfit. The foam soles with a moisture management system are
great for comfort when the weather warms ups. Embellished with camo fabric and crystal accents on rubber straps these sandals have both fashion and comfort. Whether you are heading to the beach or are out and about, you will be looking great in your Justin Camo sandals.
Style(s): 5518028
Justin Boots has set the standard for boots of the west making some of the most durable and comfortable men's, women's and kids' boots around. You can count on Justin for great western, casual and original work boots. With the finest leathers and the latest styles in western boots, Justin will always supply the best. Every pair of Justin Boots ever made is built with care and represents the hard work and dependability that won the west. In 130 years of existence men, women and children have been wearing the Justin Boots as a salute to independence and reliability. These boots are for the cowboy and cowgirl in all of us.
With unique styles like the Stampede, George Strait, Ropers and Westerns, Justin Boots continues to lead the way in boot making. The Justin Boots heritage continues to innovate with modern technology like their patented Grip-on-Demand, J-Flex Comfort System and JST while keeping the Justin Boots mystique. So whether you are a Bent Rail fan or a Tekno Crepe fan, you are guaranteed to find the right western boot for you. Check out our selection of Justin Boots and fall in love today.


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A SENIOR nurse at Trafford General Hospital is concerned some people think the hospital and its emergency care service have closed.
Clare Kirrane believes the misconception has come about in the wake of a number of changes being made to services at the hospital at the end of last year.
Clare said that while it has been widely reported that that A&E has closed and that children's services are no longer provided, this is not strictly true, as the A&E has been replaced with an Urgent Care Centre, which is no longer 24/7.
The hospital also continues to provide a range of outpatient, diagnostic and day surgery services for adults and children.
Clare said: "The new Urgent Care Centre works in much the same way as the previous A&E department, the only difference being that we don't treat people with life-threatening conditions.
"It is open from 8am to midnight, seven days a week, every day of the year.
Clare, who joined the Trafford team last year after 31 years at Manchester Royal Infirmary, said: "We can treat a wide range of conditions from minor injuries and illnesses to suspected fractures and wounds.
"If someone has a very serious condition that proves to be life-threatening or requires surgery, we will treat and stabilise them and arrange for their safe transfer the most appropriate hospital.
"We see adults and children of all ages."


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We're here to answer your questions about Globus' vacations and itineraries, as well as any of our current deals or offers. Just fill out the contact information below and a Globus expert will be in touch with you. Need an answer right away? Call us at 866.755.8581
Your personal information will be used solely for purposes of responding to your request and to provide you with updates and information. Additional information is available in our Privacy Policy.


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Hyperstat Side Effects
Generic Name: diazoxide
Note: This page contains information about the side effects of diazoxide. Some of the dosage forms included on this document may not apply to the brand name Hyperstat.
For the Consumer
Applies to diazoxide: oral capsule, oral suspension
In addition to its needed effects, some unwanted effects may be caused by diazoxide (the active ingredient contained in Hyperstat). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking diazoxide:Rare
- Chest pain
- Abdominal or stomach pain
- black, tarry stools
- blood in the urine
- bloody nose
- blurred vision
- confusion
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- extreme thirst
- fast, irregular, pounding, or racing heartbeat or pulse
- fever
- flushed, dry skin
- fruit-like breath odor
- heavier menstrual periods
- increased hunger
- increased thirst
- increased urination
- loss of consciousness
- nausea
- pinpoint red spots on the skin
- seizures
- skin rash
- stomachache
- sweating
- troubled breathing
- unexplained weight loss
- unusual bleeding or bruising
- unusual tiredness or weakness
- urinating large amounts or urinating very little
- vomiting
- weakness
Minor Side Effects
Some of the side effects that can occur with diazoxide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Increased hair growth, especially on the forehead, back, arms, and legs
- Loss of appetite
- loss of taste
- weight loss
For Healthcare Professionals
Applies to diazoxide: compounding powder, injectable solution, oral capsule, oral suspension
The most common reactions reported following diazoxide (the active ingredient contained in Hyperstat) administration include hypotension (7%), nausea and vomiting (4%), dizziness and weakness (2%).[Ref]
Cardiovascular effects including sodium and water retention following repeated injections, hypotension, shock, myocardial ischemia, myocardial and cerebral infarction, angina, atrial and ventricular arrhythmias, marked electrocardiographic changes, optic nerve infarction, supraventricular tachycardia and palpitation, bradycardia, and chest discomfort have been reported.[Ref]
Angina with myocardial and cerebral infarction have been associated with the use of a 300 mg intravenous dose of diazoxide.
One case of optic nerve infarction was reported following a single 300 mg bolus dose of diazoxide, as a result of a sudden reduction in diastolic pressure.
Results from one prospective trial conducted in patients with severe hypertension and coronary artery disease showed a 50% incidence of ischemic changes in the electrocardiogram following single 300 mg bolus injections of diazoxide.[Ref]
Nervous system
Nervous system affects reported following diazoxide (the active ingredient contained in Hyperstat) administration include cerebral ischemia, convulsions, paralysis, confusion, numbness of the hands, orthostatic hypotension, sweating, flushing, generalized or localized sensations of warmth, headache, dizziness, lightheadedness, sleepiness, lethargy, somnolence, drowsiness, euphoria, tinnitus, momentary loss of hearing, weakness and anxiety.[Ref]
Gastrointestinal side effects have been rarely reported and include acute pancreatitis, nausea, vomiting, abdominal discomfort, anorexia, alteration in taste, parotid swelling, salivation, dry mouth, lacrimation, ileus, constipation and diarrhea.[Ref]
Metabolic effects including hyperglycemia have been reported in diabetic and nondiabetic patients, especially after repeated injections. Transient retention of nitrogenous wastes has also been reported.[Ref]
Respiratory effects including dyspnea, cough and choking sensation have been reported.[Ref]
Hypersensitivity reactions characterized by rash, leukopenia, fever and papilledema induced by plasma volume expansion secondary to the administration of diazoxide (the active ingredient contained in Hyperstat) have been reported.[Ref]
Other effects including warmth or pain along the injected vein, cellulitis and/or phlebitis at the injection site of extravasation, back pain, increased nocturia, malaise, blurred vision, hirsutism, and decreased libido have been reported.[Ref]
1. "Product Information. Hyperstat I.V. (diazoxide)." Schering Corp, Kenilworth, NJ.
Not all side effects for Hyperstat may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Hyperstat (diazoxide)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: agents for hypertensive emergencies
Consumer resources
Other brands: Proglycem
Professional resources
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.


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To learn more, please visit our dedicated website.


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Seafield Holiday Homes represents one of the foremost holiday home complexes in the holiday resort of Tramore. With years of experience in dealing with visitors from all over the world, you can be assured of an excellent service and attention to detail by our staff.
Tramore is one of the foremost holiday resorts in Ireland. Situated in the South East of the country, Tramore boasts a 3 mile beach as well as a superb promenade featuring amusements, shops and other holiday businesses that are sure to enhance your visit!


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NBAA and the General Aviation Manufacturers Association (GAMA) have begun television and newspaper advertising for their 'No Plane No Gain' initiative to tout the utility of business aircraft and to counter severely negative images, generated during the bailout debate, of corporate executives jetting about the country in plush cabins with cushy seats and wood-paneled interiors.
The advertising effort began March 1 with a 30-second television spot broadcast during a series of network public- affairs shows, including nationwide placement on ABC's This Week with George Stephanopoulos, as well as placement on NBC's Meet the Press and Fox News Sunday in select markets.
The campaign covers ad placements on Washington, D.C.-area cable television networks, including Fox, CNN, CNBC and MSNBC.
"As we said when we launched 'No Plane, No Gain,' policymakers and opinion leaders need to understand business aviation is essential to America," said NBAA president and CEO Ed Bolen. "This advertising reminds our target audience that business aviation works for America by creating over one million jobs, providing a lifeline to communities without airline service, helping companies be more productive and providing humanitarian support for people in need."
GAMA president and CEO Pete Bunce agreed. "The 'No Plane, No Gain' ads put forward the real face of business aviation: the factory workers, community leaders, businesspeople and others who make up the business aviation community in America today."
The multimedia approach to "No Plane, No Gain" also includes a Web site, YouTube placements, podcasts, webinars, interviews with television media organizations and other news sources, as well as other initiatives. Regular reports detailing the campaign's progress are available, along with a host of resources for the business aviation community, at www. noplanenogain.org.
NBAA and GAMA announced the revival of the "No Plane, No Gain" campaign at GAMA's annual industry review and market outlook briefing February 17 in Washington, D.C. The original "No Plane, No Gain" campaign was introduced in 1993 to highlight the benefits of business aircraft and to help fuel passage of the General Aviation Revitalization Act of 1994.


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I have a palo verde tree in my front yard and recently I noticed a large number of pencil size branches have been breaking off the tree. When I examine the branches I see a hole in the side near the base, and the stem is hollow at the point of attachment. What could be causing this and what should I do about it?
A: A beetle in the Bostrichidae family called Amphicerus simplex causes the damage. It has no official common name so I am calling it the palo verde stem borer since that is what it does. These beetles are known for their boring activity, so much so that we commonly call the family of beetles to which it belongs the branch and twig borers and powderpost beetles.
This is a common beetle in the desert areas of Mexico, New Mexico, Texas and Arizona. Research from the 1950s lists three hosts: little leaf horsebean (aka yellow or foothill palo verde), blue palo verde and mistletoe. There is not much more info than that about this insect. Since it is a native species, the lack of information usually indicates it is of little concern. It would be interesting to know if these beetles are a widespread problem every year that goes underreported or if they are simply a sporadic problem.
I hear about a few of these cases each year so I will be interested to see if there are more. I would not recommend treating the tree unless it turns out to be a problem every year. A little pruning is good. If we can train the beetles to bore into the right branches it will be all good.
Sometimes I see tumbleweed rolling across the road when I am driving out in the county. Why don't I see this weed in the city?
A: Tumbleweed (aka Russian thistle) is a summer annual weed native to southeastern Russia and it is very well adapted to desert conditions. It is a species that takes advantage of recently disturbed soil. It doesn't need much water to germinate and it has a long taproot to access water as it grows. Unlike many weeds, the seed does not last long in the soil so managing young plants before they produce seed is usually enough to keep it under control.
Typically we see tumbleweed growing in roadside ditches, near agricultural fields and in recently cleared land for construction. Well-managed landscapes seldom have a problem because they are not left bare for long and many people manage their weeds. Also these plants spread seed by tumbling and so having some nearby and room to roll makes for a problem that persists unless they are managed. At our Campus Agricultural Center in Tucson, the farm supervisor, Ken Kriederman, says they look for it and treat it when the plant is small so it won't get out of hand. When it is young the plant is dark green and succulent and barely resembles the dead brown tumbling plant that has become iconic of the Southwest.
I have a mature Aleppo pine tree that is showing some browning on the needles. Could this be a disease? What should I do about it?
A: The Aleppo pine is a heat tolerant species from the Mediterranean region that is commonly used in our area. We often see needles with yellowing and browning and there are few potential causes. The first is a reaction to the summer heat and this is a normal condition that the trees outgrow once cooler temperatures occur. Secondly, this tree, like many mature trees, requires regular watering. In the spring, summer, and fall, every two to three weeks deep watering to 24 to 36 inches is best. This can be reduced to once a month in winter. Watering a big tree can be challenging because the root zone is also big and it is important to place emitters near the drip line of the tree to be most effective. Thirdly, there are mites and aphids that sometimes infest these trees and can cause browning of needles. The mites and aphids can be seen with a microscope and are a good thing to rule out. You can bring branch samples to the Cooperative Extension office for help with the diagnosis.


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The Blue Earth County Historical Society presents the history and heritage of Blue Earth County through our Speaker's Bureau which consists of Educational Programs, Informational Presentations and Historic Site Tours available for groups, organizations, clubs, and more!
Educational programs are a virtual tour of the Society's collections through a historical topic.Presenters are experts, scholars and/or historians knowledgeable in their topic that represent the Society.Educational programs are $25 per program per speaking engagement.See the list below for Educational Program.
Informational presentations are focused on the Historical Society's history, a program or upcoming exhibit, publication or a service provided by the Society.Promotional presentations are free. Presentations focused on BECHS publications will include the availability of that book for purchase by participants.See the list below for Promotional presentations.
To arrange an Educational Program or Informational Presentation, contact Heather at 507-345-5566 or email@example.com. All programs and presentations feature a PowerPoint presentation unless otherwise noted. Presenters will bring own equipment if necessary.
Educational Program - $25 fee
List of Programs:
- 1918 Flu Epidemic
- Beginning Genealogy
- Blue Earth County Poor Farm History
- Cemetery Preservation (optional cemetery tour available)
- Cemetery Research 101
- Demystifying Your Family Photographs
- Historic Mankato Floods: 1881-1969
- Historic Minnesota Blizzards
- How to Do Your House History
- Lost Historic Blue Earth County Buildings
- Photograph and Paper Preservation 101
- Pocket and Purses (no PowerPoint)
- Quilt History (no PowerPoint)
- Researching Local Newspapers
- Researching Probate Records
- Researching the Census
- Uncovering Your Family History
- Welsh in Blue Earth County
- Women's Club Movement in Blue Earth County
More added on a regular basis
Informational Presentation – Free (Limit of 2 per year)
- History and Introduction to the Blue Earth County Historical Society
- History of the Blue Earth County Courthouse – based on the BECHS book and DVD of the same title (optional DVD showing available)
- Meet the Hubbard's – based on the book by the same title
- Remarkable Men of Garden City - based on the BECHS book by the same title
- The Front Street Project
- The Multifaceted Carp - based on the BECHS book by the same title
- History of Minneopa State Park - based on the BECHS book by the same title


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Todays punniest headline; "Just chopping out for an ice cream", thanks to ever-punning The Sun. They report that RAF pilots landed a helicopter on a beach just to get some Magnum ice-creams. Somewhere in the Magnum marketing offices, a bunch of suits are high-fiving each other right now.
@Mister_Wang notes it would ave been perfect had it been a Klondyke bar.


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Healthy Living Program
Do you feel like you are always swinging on a pendulum when it comes to your health and fitness? Maybe you're not ready to sign up for your first 5k or Olympic Triathlon and claim the title of "athlete", but you are ready to make fitness a priority in your life. Working with Carrie will provide you with the tools to maintain your motivation, accomplish your health and fitness goals, and make a lasting change.
4 month program
8 sessions
Set up your free 30 minute phone consultation with Carrie today!


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Steele Creek
Goodwill Steele Creek
12716 South Tryon Street
Charlotte, NC 28273
(704) 587-6183
View map
Hours of Operation:
Monday – Saturday 9:00am – 9:00pm
Sunday 10:00am – 7:00pm
All Goodwill retail stores also serve as donation drop-off locations.
Standard pricing on clothing and household items found at Goodwill stores can be found on our Price List page. Small appliances, furniture, antiques, exercise equipment, and other special donations are priced individually based on quality and condition.
How Your Purchases Change Lives
When you shop at Goodwill, you're not the only one who gets a great deal. Last year, sales from Goodwill stores funded employment training, job placement services, financial education, youth mentoring and more to thousands of people right here in your community.
Tell Us Your Goodwill Story
When you walk into a Goodwill store, you never know what you'll find. Share your great finds and deals, and unite with other Goodwill shoppers on our Facebook page.
Want To Join Our Team?
If you are interested in working for an organization that changes lives, learn about current job openings.