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When you run AnalyzeCovariates to analyze your BQSR outputs, you may encounter an error starting with this line:
org.broadinstitute.sting.utils.R.RScriptExecutorException: RScript exited with 1. Run with -l DEBUG for more info.
The main reason why this error often occurs is simple, and so is the solution. The script depends on some external R libraries, so if you don't have them installed, the script fails. To find out what libraries are necessary and how to install them, you can refer to this tutorial.
One other common issue is that the version of ggplot2 you have installed is very recent and is not compatible with the BQSR script. If so, download this Rscript file and use it to generate the plots manually according to the instructions below.
If you have already checked that you have all the necessary libraries installed, you'll need to run the script manually in order to find out what is wrong. To new users, this can seem complicated, but it only takes these 3 simple steps to do it!
-l DEBUG (that's a lowercase L, not an uppercase i, to be clear) and
-csv my-report.csv (where you can call the .csv file anything; this is so the intermediate csv file will be saved).
The snippet below shows you the components of the R script command line that AnalyzeCovariates uses.
INFO 18:04:55,355 AnalyzeCovariates - Generating plots file 'RTest.pdf'
DEBUG 18:04:55,672 RecalUtils - R command line: Rscript (resource)org/broadinstitute/gatk/utils/recalibration/BQSR.R /Users/schandra/BQSR_Testing/RTest.csv /Users/schandra/BQSR_Testing/RTest.recal /Users/schandra/BQSR_Testing/RTest.pdf
DEBUG 18:04:55,687 RScriptExecutor - Executing:
DEBUG 18:04:55,688 RScriptExecutor - Rscript
DEBUG 18:04:55,688 RScriptExecutor - -e
DEBUG 18:04:55,688 RScriptExecutor - tempLibDir = '/var/folders/j9/5qgr3mvj0590pd2yb9hwc15454pxz0/T/Rlib.2085451458391709180';source('/var/folders/j9/5qgr3mvj0590pd2yb9hwc15454pxz0/T/BQSR.761775214345441497.R');
DEBUG 18:04:55,689 RScriptExecutor - /Users/schandra/BQSR_Testing/RTest.csv
DEBUG 18:04:55,689 RScriptExecutor - /Users/schandra/BQSR_Testing/RTest.recal
DEBUG 18:04:55,689 RScriptExecutor - /Users/schandra/BQSR_Testing/RTest.pdf
So, your full command line will be:
RScript BQSR.R RTest.csv RTest.recal RTest.pdf
Please note:
For new users, the easiest way to do this is to do it from within an IDE program like RStudio. Or, you can start up R at the command line and run it that way, whatever you are comfortable with.
The GATK runs natively on most if not all flavors of UNIX, which includes MacOSX, Linux and BSD. It is possible to get it running on Windows using Cygwin, but we don't provide any support nor instructions for that.
The GATK is a Java-based program, so you'll need to have Java installed on your machine. The Java version should be at 1.7 (at this time we don't officially support 1.8, and 1.6 no longer works). You can check what version you have by typing
java -version at the command line. This article has some more details about what to do if you don't have the right version. Note that at this time we only support the Sun/Oracle Java JDK; OpenJDK is not supported.
Some of the GATK tools produce plots using R, so if you want to get the plots you'll need to have R and Rscript installed, as well as several R libraries. Full details can be found in the Tutorial on installing required software.
The GATK does not have a Graphical User Interface (GUI). You don't open it by clicking on the
.jar file; you have to use the Console (or Terminal) to input commands. If this is all new to you, we recommend you first learn about that and follow some online tutorials before trying to use the GATK. It's not difficult but you'll need to learn some jargon and get used to living without a mouse. Trust us, it's a liberating experience :)
The GATK build system uses the Ivy dependency manager to make it easy for our users to add additional dependencies. Ivy can pull the latest jars and their dependencies from the Maven repository, making adding or updating a dependency as simple as adding a new line to the
ivy.xml file.
If your tool is available in the maven repository, add a line to the
ivy.xml file similar to the following:
<dependency org="junit" name="junit" rev="4.4" />
If you would like to add a dependency to a tool not available in the maven repository, please email firstname.lastname@example.com
Because we work so closely with the SAM-JDK/Picard team and are critically dependent on the code they produce, we have a special procedure for updating the SAM/Picard jars. Please use the following procedure to when updating
sam-*.jar or
Download and build the latest versions of Picard public and Picard private (restricted to Broad Institute users) from their respective svns.
Get the latest svn versions for picard public and picard private by running the following commands:
svn info $PICARD_PUBLIC_HOME | grep "Revision" svn info $PICARD_PRIVATE_HOME | grep "Revision"
Rename the jars and xmls in
$STING_HOME/settings/repository/net.sf to
Update the jars in
$STING_HOME/settings/repository/net.sf with their newer equivalents in
$STING_HOME/settings/repository/net.sf with the appropriate version number (
Create the picard private jar with the following command:
ant clean package -Dexecutable=PicardPrivate -Dpicard.dist.dir=${PICARD_PRIVATE_HOME}/dist
picard-private-parts-*.jar in
$STING_HOME/settings/repository/edu.mit.broad to
picard-private-parts-*.jar in
$STING_HOME/settings/repository/edu.mit.broad with the
picard-private-parts.jar in
$STING_HOME/settings/repository/edu.mit.broad to reflect the new revision and publication date.
Hi, this took me a while to debug, so I'm posting the solution here. I started by downloading a clean copy of GATK core platform from GitHub. When I first tried building by running ant, I got the compiler errors below. The reason turned out to be that an unrelated jar (gsea2-2.0.12.jar) was on my CLASSPATH (this is from another Broad tool I've been using - Gene Set Enrichment Analysis). gsea2-2.0.12.jar apparently contains outdated versions of apache math and io packages which conflict with the GATK versions. Taking this jar off my CLASSPATH fixed the issue.
Ps. the compiler errors were:
gatk.compile.internal.source: [javac] Compiling 681 source files to /prog/GATK/gatk_platform_git/build/java/classes [javac] /prog/GATK/gatk_platform_git/public/java/src/org/broadinstitute/sting/commandline/ParsingEngine.java:260: error: incompatible types [javac] for (String line: FileUtils.readLines(file)) [javac] ^ [javac] required: String [javac] found: Object [javac] /prog/GATK/gatk_platform_git/public/java/src/org/broadinstitute/sting/utils/MannWhitneyU.java:50: error: no suitable constructor found for NormalDistributionImpl(double,double,double) [javac] private static NormalDistribution APACHE_NORMAL = new NormalDistributionImpl(0.0,1.0,1e-2); [javac] ^ [javac] constructor NormalDistributionImpl.NormalDistributionImpl() is not applicable [javac] (actual and formal argument lists differ in length) [javac] constructor NormalDistributionImpl.NormalDistributionImpl(double,double) is not applicable [javac] (actual and formal argument lists differ in length) [javac] Note: Some input files use or override a deprecated API. [javac] Note: Recompile with -Xlint:deprecation for details. [javac] Note: Some input files use unchecked or unsafe operations. [javac] Note: Recompile with -Xlint:unchecked for details. [javac] 2 errors BUILD FAILED /prog/GATK/gatk_platform_git/build.xml:454: Compile failed; see the compiler error output for details.


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Rumor: Mirror's Edge 2 Has More Fluid Combat, Open World Multiplayer - NewsBrent Galietti, posted on 13 March 2014 / 2,686 Views
Free-running platform/action-adventure game Mirror's Edge gained a small but devout fanbase when it released back in 2008. The reboot, Mirror's Edge 2, was formally announced at E3 last year, but details have been scarce. Australian website Rocket Chainsaw claims to have seen footage of the game in action and has some information to report.
The E3 2013 trailer was generally unscripted and in real time, including the new combat systems. Combat will use "a deeper system that emphasises speed and fluidity" instead of "useless gunplay and one button" combat sequences. Combat moves include pushing enemies and objects, punch combos, wall running, flips and third-person take down sequences. Developer DICE considers Mirror's Edge 2 to be a "racing game at heart" and is developing the game around parkour with occasional pauses to defeat an opponent.
DICE's goal is to develop an "open world, living breathing city" for players to traverse. The open world will be an online multiplayer playground where players can drop in and out seamlessly, interacting with other players as much or as little as desired. It is unclear whether this means Mirror's Edge 2 will require an always online connection or if this mode can be turned off if the player chooses to play offline. Time trials were also mentioned as a multiplayer activity.
Mirror's Edge 2 is targeted to release in 2016 for Xbox One, PlayStation 4, PC and Mac.
Bear in mind that the above are all rumors and may or may not come to pass in the final product. EA, for their effort, offered a standard response to these rumors:
"EA will not be commenting on rumours. For information on Mirror's Edge 2, please check our official channels."
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I've made a CUDA program for 2D convolution and now want to compare it to some non-CUDA implementation to measure the speedup.
I could compare to my own implementation in plain C using the classical multiple loop approach or matlab's conv2 but it doesn't feel like a legit/fair comparison, since they're not the fastest implementations out there.
Also I was thinking of trying OpenCV and I've been looking for a SIMD optimized version with no luck. Any advice, should I go with OpenCV?
NOTE: I've read other questions, including this one, but the answer is basically the same as my plain C code or a discussion of the various methods available.


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By: Megan J
German pancakes are one of the simplest pancakes to make, plus they are absolutely delicious. The buttery goodness of these pancakes will surely hit the spot and please any crowd. These pancakes are traditionally made in a Pyrex 9×11 baking dish. However, since we have a new addition to the Camp Chef line, we thought we would try them out in the new 13″ Square Dutch Oven.
- 9 Tablespoons Butter
- 9 Eggs
- 2 ¼ Cups Flour
- 2 ¼ Cups Milk
- ¾ Teaspoon Salt
Preheat the oven to 400 degrees.
While the oven is preheating, add 9 Tablespoons of butter to the Square Dutch Oven and insert into oven. The butter will melt as the oven preheats. Make sure to watch the butter closely to prevent it from burning. You may need to swirl the butter around the bottom of the Dutch Oven to ensure the entire surface is covered with butter.
Mix the eggs, flour, milk, and salt together with an electric mixer or a Wisk.
The batter should be thin and free from clumps.
Once the butter is melted and the oven is preheated, pour the batter into the hot butter. Make sure to pour the batter into the center of the Dutch Oven.
Bake at 400 degrees for 20 minutes. The pancakes will expand and turn golden brown.
Once the pancakes are done, top them off with your favorite toppings. We used maple syrup and powdered sugar, but fruit would taste amazing on these pancakes.
I was amazed at how well these pancakes turned out in the Square Dutch Oven. They were cooked evenly throughout and browned to perfection. The office devoured them instantly and couldn't get enough of them. My family makes German pancakes every year for Christmas morning. We love them because they are so easy to make, and taste fantastic! One benefit of these pancakes is that while they are baking you can prepare the rest of the meal so everything is done at the same time. German pancakes are the perfect addition to any holiday breakfast!
Want more great information, recipes, and giveaways from Camp Chef? 'Like' us and follow us on our facebook page!


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Tottenham v Villa team news: Find out who's fit for Spurs game
Gabby Agbonlahor looks set to return for Tottenham v Villa this weekend.
Villa travel to White Hart Lane on Sunday for the final day clash.
Agbonlahor [knee] came off early in the win over Hull before missing out at Man City.
But he has given Paul Lambert a welcome boost by confirming his fitness.
However, Marc Albrighton is touch and go for the Tottenham game.
Albrighton [groin] also picked up an injury against the Tigers and, like Agbonlahor, didn't figure at the Etihad Stadium.
He is less likely to be ready to face Tim Sherwood's side.
It would be a shame as White Hart Lane holds special memories for the winger, who scored his first senior goal there under Gerard Houllier in October 2010.
However, it looks like he will miss out.
Lambert said: "Gabby is back fit. Marc is still struggling.
"We will see how the lads are. There are a lot of tired legs in there after the Man City game with the effort they put in.
"But we will go and try to win."
Check out all the details about new season tickets.
Season Tickets
on sale
Buy our
2015/16 kits


text:
Welcome to the Archived, Readonly Zimbra Collaboration forums. Heres the place where we talked about all things related to Zimbra email products. Registrations and postings are disabled here.
Be sure to visit https://www.zimbra.com/forums to start new discussions and to find the latest answers to questions being asked.
I need a local resource for Zimbra/Unbutu upgrade and break fix. Northern Illinois area.
Forum Rules


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Puregon 300 IU/0.36 ml, 600 IU/0.72 ml , 900 IU/1.08 ml solution for injection
Last Updated on eMC 09-May-2014 View changes | Merck Sharp & Dohme Limited Contact details
- 1. Name of the medicinal product
- 2. Qualitative and quantitative composition
- 3. Pharmaceutical form
- 4. Clinical particulars
- 4.1 Therapeutic indications
- 4.2 Posology and method of administration
- 4.3 Contraindications
- 4.4 Special warnings and precautions for use
- 4.5 Interaction with other medicinal products and other forms of interaction
- 4.6 Fertility, pregnancy and lactation
- 4.7 Effects on ability to drive and use machines
- 4.8 Undesirable effects
- 4.9 Overdose
- 5. Pharmacological properties
- 5.1 Pharmacodynamic properties
- 5.2 Pharmacokinetic properties
- 5.3 Preclinical safety data
- 6. Pharmaceutical particulars
- 6.1 List of excipients
- 6.2 Incompatibilities
- 6.3 Shelf life
- 6.4 Special precautions for storage
- 6.5 Nature and contents of container
- 6.6 Special precautions for disposal and other handling
- 7. Marketing authorisation holder
- 8. Marketing authorisation number(s)
- 9. Date of first authorisation/renewal of the authorisation
- 10. Date of revision of the text
- 11. Legal category
In adult females:Puregon is indicated for the treatment of female infertility in the following clinical situations:• Anovulation (including polycystic ovarian syndrome, PCOS) in women who have been unresponsive to treatment with clomifene citrate.• Controlled ovarian hyperstimulation to induce the development of multiple follicles in medically assisted reproduction programs [e.g. in vitro fertilisation/embryo transfer (IVF/ET), gamete intra-fallopian transfer (GIFT) and intracytoplasmic sperm injection (ICSI)].
In adult males:• Deficient spermatogenesis due to hypogonadotrophic hypogonadism.
Dosage in the femaleThere are great inter- and intra-individual variations in the response of the ovaries to exogenous gonadotrophins. This makes it impossible to set a uniform dosage scheme. The dosage should, therefore, be adjusted individually depending on the ovarian response. This requires ultrasound assessment of follicular development. The concurrent determination of serum oestradiol levels may also be useful.When using the pen-injector, it should be realised that the pen is a precision device which accurately delivers the dose to which it is set. It was shown that on average an 18% higher amount of FSH is given with the pen compared with a conventional syringe. This may be of particular relevance when switching between the pen-injector and a conventional syringe within one treatment cycle. Especially when switching from a syringe to the pen, small dose adjustments may be needed to prevent too high a dose being given.Based on the results of comparative clinical studies it is considered appropriate to give a lower total dosage of Puregon over a shorter treatment period than generally used for urinary FSH, not only in order to optimise follicular development but also to reduce the risk of unwanted ovarian hyperstimulation (see Section 5.1).Clinical experience with Puregon is based on up to three treatment cycles in both indications. Overall experience with IVF indicates that in general the treatment success rate remains stable during the first four attempts and gradually declines thereafter.• AnovulationA sequential treatment scheme is recommended starting with daily administration of 50 IU Puregon. The starting dose is maintained for at least seven days. If there is no ovarian response, the daily dose is then gradually increased until follicle growth and/or plasma oestradiol levels indicate an adequate pharmacodynamic response. A daily increase of oestradiol levels of 40-100% is considered to be optimal. The daily dose is then maintained until pre-ovulatory conditions are reached. Pre-ovulatory conditions are reached when there is ultrasonographic evidence of a dominant follicle of at least 18 mm in diameter and/or when plasma oestradiol levels of 300-900 picograms/ml (1000-3000 pmol/l) are attained. Usually, 7 to 14 days of treatment is sufficient to reach this state. The administration of Puregon is then discontinued and ovulation can be induced by administering human chorionic gonadotrophin (hCG). If the number of responding follicles is too high or oestradiol levels increase too rapidly, i.e. more than a daily doubling for oestradiol for two or three consecutive days, the daily dose should be decreased. Since follicles of over 14 mm may lead to pregnancies, multiple pre-ovulatory follicles exceeding 14 mm carry the risk of multiple gestations. In that case hCG should be withheld and pregnancy should be avoided to prevent multiple gestations.• Controlled ovarian hyperstimulation in medically assisted reproduction programsVarious stimulation protocols are applied. A starting dose of 100-225 IU is recommended for at least the first four days. Thereafter, the dose may be adjusted individually, based upon ovarian response. In clinical studies it was shown that maintenance dosages ranging from 75-375 IU for six to twelve days are sufficient, although longer treatment may be necessary. Puregon can be given either alone, or, to prevent premature luteinisation, in combination with a GnRH agonist or antagonist. When using a GnRH agonist, a higher total treatment dose of Puregon may be required to achieve an adequate follicular response. Ovarian response is monitored by ultrasound assessment. The concurrent determination of serum oestradiol levels may also be useful. When ultrasound assessment indicates the presence of at least three follicles of 16-20 mm, and there is evidence of a good oestradiol response (plasma levels of about 300-400 picograms/ml (1000-1300 pmol/l) for each follicle with a diameter greater than 18 mm), the final phase of maturation of the follicles is induced by administration of hCG. Oocyte retrieval is performed 34-35 hours later.
Dosage in the malePuregon should be given at a dosage of 450 IU/week, preferably divided in 3 dosages of 150 IU, concomitantly with hCG. Treatment with Puregon and hCG should be continued for at least 3 to 4 months before any improvement in spermatogenesis can be expected. To assess the response, semen analysis is recommended 4 to 6 months after the beginning of treatment. If a patient has not responded after this period, the combination therapy may be continued; current clinical experience indicates that treatment for up to 18 months or longer may be necessary to achieve spermatogenesis.
Paediatric populationThere is no relevant use of Puregon in the paediatric population for the approved indication.
Method of administrationPuregon solution for injection in cartridges has been developed for use in the Puregon Pen and should be administered subcutaneously. The injection site should be alternated to prevent lipoatrophy.Using the pen, injection of Puregon can be carried out by the patient, provided that proper instructions are given by the physician.
For males and females• Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.• Tumours of the ovary, breast, uterus, testis, pituitary or hypothalamus.• Primary gonadal failure
Additionally for females• Undiagnosed vaginal bleeding.• Ovarian cysts or enlarged ovaries, not related to polycystic ovarian syndrome (PCOS).• Malformations of the reproductive organs incompatible with pregnancy.• Fibroid tumours of the uterus incompatible with pregnancy.
Antibiotic hypersensitivity reactions• Puregon may contain traces of streptomycin and/or neomycin. These antibiotics may cause hypersensitivity reactions in susceptible persons.
Infertility evaluation before starting treatmentBefore starting treatment, the couple's infertility should be assessed as appropriate. In particular, patients should be evaluated for hypothyroidism, adrenocortical insufficiency, hyperprolactinemia and pituitary or hypothalamic tumours, and appropriate specific treatment given.
In females
Ovarian Hyperstimulation Syndrome (OHSS)OHSS is a medical event distinct from uncomplicated ovarian enlargement. Clinical signs and symptoms of mild and moderate OHSS are abdominal pain, nausea, diarrhoea, mild to moderate enlargement of ovaries and ovarian cysts. Severe OHSS may be life-threatening. Clinical signs and symptoms of severe OHSS are large ovarian cysts, acute abdominal pain, ascites, pleural effusion, hydrothorax, dyspnoea, oliguria, haematological abnormalities and weight gain. In rare instances, venous or arterial thromboembolism may occur in association with OHSS. Transient liver function test abnormalities suggestive of hepatic dysfunction with or without morphologic changes on liver biopsy have also been reported in association with OHSS.OHSS may be caused by administration of human Chorionic Gonadotropin (hCG) and by pregnancy (endogenous hCG). Early OHSS usually occurs within 10 days after hCG administration and may be associated with an excessive ovarian response to gonadotropin stimulation. Late OHSS occurs more than 10 days after hCG administration, as a consequence of the hormonal changes with pregnancy. Because of the risk of developing OHSS, patients should be monitored for at least two weeks after hCG administration.Women with known risk factors for a high ovarian response may be especially prone to the development of OHSS during or following treatment with Puregeon. For women having their first cycle of ovarian stimulation, for whom risk factors are only partially known, close observation for early signs and symptoms of OHSS is recommended.To reduce the risk of OHSS, ultrasonographic assessments of follicular development should be performed prior to treatment and at regular intervals during treatment. The concurrent determination of serum oestradiol levels may also be useful. In ART there is an increased risk of OHSS with 18 or more follicles of 11 mm or more in diameter. When there are 30 or more follicles in total it is advised to withhold hCG administration.Depending on the ovarian response, the following measurements can be considered to reduce OHSS: - withhold further stimulation with a gonadotropin for a maximum of 3 days (coasting);- withhold hCG and cancel the treatment cycle;- administer a dose lower than 10,000 IU of urinary hCG for triggering final oocyte maturation, e.g. 5,000 IU urinary hCG or 250 micrograms rec-hCG (which is equivalent to approximately 6,500 IU of urinary hCG);- cancel the fresh embryo transfer and cryopreserve embryos;- avoid administration of hCG for luteal phase support.If OHSS develops, standard and appropriate management of OHSS should be implemented and followed.
Multiple PregnancyMultiple pregnancies and births have been reported for all gonadotropin treatments, including Puregon. Multiple gestation, especially high order, carries an increased risk of adverse maternal (pregnancy and delivery) complications) and perinatal (low birth rate) outcomes. For anovulatory women undergoing ovulation induction, monitoring follicular development with transvaginal ultrasonography may aid in determining whether or not to continue the cycle in order to reduce the risk of multiple pregnancies. The concurrent determination of serum oestradiol levels may also be useful. The patients should be advised of the potential risks of multiple births before starting treatment.In women undergoing Assisted Reproduction Technologies (ART) procedures, the risk of a multiple pregnancy is mainly related to the number of embryos transferred. When used for an ovulation induction cycle, appropriate FSH dose adjustment(s) should prevent multiple follicle development.
Ectopic PregnancyInfertile women undergoing ART, and particularly IVF, often have tubal abnormalities the incidence of ectopic pregnancies might be increased. Early ultrasound confirmation that a pregnancy is intrauterine is therefore important.
Spontaneous AbortionRates of pregnancy loss in women undergoing assisted reproduction techniques are higher than in the normal population.
Vascular ComplicationsThromboembolic events, both in association with and separate from OHSS, have been reported following treatment with gonadotropins, including Puregon. Intravascular thrombosis, which may originate in venous or arterial vessels, can result in reduced blood flow to vital organs or the extremities. In women with generally recognised risk factors for thromboembolic events, such as a personal or family history, severe obesity or thrombophilia, treatment with gonadotropins, including Puregon, may further increase this risk. In these women the benefits of gonadotropin administration, including Puregon, need to be weighed against the risks. It should be noted, however, that pregnancy itself also carries an increased risk of thrombosis.
Congenital MalformationsThe incidence of congenital malformations after ART may be slightly higher than after spontaneous conceptions. This is thought to be due to differences in parental characteristics (e.g., maternal age, sperm characteristics) and multiple gestations.
Ovarian TorsionOvarian torsion has been reported after treatment with gonadotropins, including Puregon. Ovarian torsion may be associated with other risk factors such as OHSS, pregnancy, previous abdominal surgery, past history of ovarian torsion, previous or current ovarian cyst and polycystic ovaries. Damage to the ovary due to reduced blood supply can be limited by early diagnosis and immediate detorsion.
Ovarian and other Reproductive System NeoplasmsThere have been reports of ovarian and other reproductive system neoplasms, both benign and malignant, in women who have undergone multiple treatment regimens for infertility treatment. It is not established whether or not treatment with gonadotrophins increases the risk of these tumours in infertile women.
Other Medical ConditionsMedical conditions that contraindicate pregnancy should also be evaluated before starting treatment with Puregon.
In males
Primary Testicular FailureElevated endogeneous FSH levels in men are indicative of primary testicular failure. Such patients are unresponsive to Puregon/hCG therapy.
FertilityPuregon is used in the treatment of women undergoing ovarian induction or controlled ovarian hyperstimulation in assisted reproduction programmes. In males Puregon is used in the treatment of deficient spermatogenesis due to hypogonadotrophic hypogonadism. For posology and method of administration, see section 4.2.
PregnancyThe use of Puregon during pregnancy is not indicated. In case of inadvertent exposure during pregnancy, clinical data are not sufficient to exclude a teratogenic effect of recombinant FSH. However, to date, no particular malformative effect has been reported. No teratogenic effect has been observed in animal studies.
Breast-feedingThere is no information available from clinical or animal studies on the excretion of follitropin beta in milk. It is unlikely that follitropin beta is excreted in human milk due to its high molecular weight. If follitropin beta would be excreted in human milk, it would be degraded in the gastrointestinal tract of the child. Follitropin beta may affect milk production.
Treatment of females:In approximately 4% of the women treated with follitropin beta in clinical trials, signs and symptoms related to ovarian hyperstimulation syndrome (OHSS) have been reported (see section 4.4). Adverse reactions related to this syndrome include pelvic pain and/or congestion, abdominal pain and/or distension, breast complaints and ovarian enlargement.The table below lists the adverse reactions with follitropin beta reported in clinical trials in females, according to system organ class and frequency; common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100).
|Adverse reaction
|Nervous system disorders
|Gastrointestinal disorders
|Abdominal distension Abdominal pain
|Abdominal discomfort Constipation Diarrhoea Nausea
|Reproductive system and breast disorders
|OHSS Pelvic pain
|Breast complaints1Metrorrhagia Ovarian cyst Ovarian enlargement Ovarian torsion Uterine enlargement Vaginal haemorrhage
|General disorders and administration site conditions
|Injection site reaction2
|Generalised hypersensitivity reaction3
Treatment of males:The table below lists the adverse reactions with follitropin beta reported in a clinical trial in males (30 patients dosed), according to system organ class and frequency; common (≥ 1/100 to < 1/10).
|Adverse reaction
|Nervous system disorders
|Skin and subcutaneous tissue disorders
|Acne Rash
|Reproductive system and breast disorders
|Epididymal cyst Gynaecomastia
|General disorders and administration site conditions
|Injection site reaction2
Reporting of suspected adverse reactionsReporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, website www.mhra.gov.uk/yellowcard.
Mechanism of ActionFSH is indispensable in normal follicular growth and maturation, and gonadal steroid production. In the female the level of FSH is critical for the onset and duration of follicular development, and consequently for the timing and number of follicles reaching maturity. Puregon can thus be used to stimulate follicular development and steroid production in selected cases of disturbed gonadal function. Furthermore Puregon can be used to promote multiple follicular development in medically assisted reproduction programs [e.g. in vitro fertilisation/embryo transfer (IVF/ET), gamete intra-fallopian transfer (GIFT) and intracytoplasmic sperm injection (ICSI)]. Treatment with Puregon is generally followed by administration of hCG to induce the final phase of follicle maturation, resumption of meiosis and rupture of the follicle.
Clinical Efficacy and SafetyIn clinical studies comparing recFSH (follitropin beta) and urinary FSH for controlled ovarian stimulation in women participating in an assisted reproduction technology (ART) program and for ovulation induction (see tables 1 and 2 below), Puregon was more potent than urinary FSH in terms of a lower total dose and a shorter treatment period needed to trigger follicular maturation.For controlled ovarian stimulation, Puregon resulted in a higher number of oocytes retrieved at a lower total dose and with a shorter treatment period, when compared to urinary FSH.Table 1: Results of study 37608 (randomized, group comparative clinical study comparing safety and efficacy of Puregon with urinary FSH in controlled ovarian stimulation).
|Puregon(n = 546)
|u-FSH(n = 361)
|Mean no. of oocytes retrieved
|Mean total dose (no. of 75 IU ampoules)
|Mean duration of FSH stimulation (days)
|Puregon (n = 105)
|u-FSH (n = 66)
|Mean no. of follicles
|≥ 12 mm
|≥ 15 mm
|≥ 18 mm
|Median total dose (IU)a
|Median duration of treatment (days)a
AbsorptionAfter subcutaneous administration of Puregon, maximum concentration of FSH is reached within about 12 hours. Due to the sustained release from the injection site and the elimination half-life of about 40 hours (ranging from 12 to 70 hours), FSH levels remain increased for 24-48 hours. Due to the relatively long elimination half-life, repeated administration of the same dose will lead to plasma concentrations of FSH that are approximately 1.5-2.5 times higher than after single dose administration. This increase enables therapeutic FSH concentrations to be reached. The absolute bioavailability of subcutaneously administered Puregon is approximately 77%.
Distribution, biotransformation and eliminationRecombinant FSH is biochemically very similar to urinary human FSH and is distributed, metabolised, and excreted in the same way.
|(Puregon 300 IU/0.36 ml solution for injection)
|(Puregon 600 IU/0.72 ml solution for injection)
|(Puregon 900 IU/1.08ml solution for injection)
Merck Sharp & Dohme Limited
Hertford Road, Hoddesdon, Hertfordshire, EN11 9BU
+44 (0)1992 479 292
Call MSD customer services on 01992 452094
+44 (0)1992 467 272
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Cocaine was first extracted from the leaves in 1855 and by the 1870s it was a popular stimulant and tonic and used in a range of patent medicines for all sorts of ailments. The famous psychoanalyst, Sigmund Freud, recommended its use for a range of medical and psychological problems, including alcohol and morphine addiction. However, he changed his mind after he recommended cocaine to his friend for morphine addiction and the friend died of a cocaine overdose.
Doctors also used cocaine as a local anaesthetic for eye surgery and in dentistry.
Sherlock Holmes, the fictional detective in Arthur Conan Doyle's books, was a regular cocaine user. Coca laced wines were enjoyed by popes and royalty in the 19th century. Vin Mariani, for example, was popular in the 1800s, receiving enthusiastic endorsements from Pope Pius X and the Grand Rabbi of France, extoltings its 'life giving properties'. Coca Cola was originally sold as 'a valuable brain tonic and cure for all nervous afflictions' and until 1904 contained small quantities of cocaine.
At the turn of the century doctors began to warn of possible dependence and problems with its use. In America fears developed among white people about 'cocaine crazed' black people who were rebelling against new discriminatory laws. In Britain concerns arose about the use of cocaine by troops during the First World War. Hysterical press reaction claimed that this was a German plot to destroy the British Empire. In 1916 emergency laws were rushed in to ban possession of cocaine (and opium) and limit its medical use.
At the time there was very little recreational use of cocaine in Britain, although when a young actress died of an overdose in 1918, it provoked the beginnings of what became the typical exaggerated press reaction to drugs and drug using that we see today.
Cocaine was always available in this country, but it was not until the mid 1970s that cocaine became more commonly used. Sniffing cocaine became fashionable among the 'smart and successful' middle classes and was seen as a glamorous and expensive drug.
Meanwhile in America cocaine use was much more widespread and in the mid 1980s, a new more powerful form of the drug became available, smokable cocaine or crack. This became a major problem for those living in the most deprived areas of the inner city America. Gang warfare, shootings and drug related crime hit the headlines. In Britain the authorities braced themselves in anticipation of a similar situation. But while crack has come to Britain with related violence and criminal activity, it has not been anywhere near the scale of what happened in America.. However, cocaine use has increased among young people in recent years, especially among those attending all-night dance clubs.
effects and risks
Cocaine and crack are strong but short acting stimulant drugs. They tend to make users feel more alert and energetic. Many users say they feel very confident and physically strong and believe they have great mental capacities. Common physical effects include dry mouth, sweating, loss of appetite and increased heart and pulse rate. At higher dose levels users may feel very anxious and panicky. The effects from snorting cocaine start quickly but only last for up to 30 minutes without repeating the dose. The effects come on even quicker when smoking crack but are even more short lived.
"It makes you feel great and powerful and all that. The trouble is it can make you really wired. And it doesn't last that long so the temptation is to have another go. That's why I found it so moorish and it cost me a fortune".
Large doses or quickly repeating doses over a period of hours can lead to extreme anxiety, paranoia and even hallucinations. These effects usually disappear as the drug is eliminated from the body. The after-effects of cocaine and crack use may include fatigue and depression as people come down from the high. Excessive doses can cause death from respiratory or heart failure but this is rare.
Cocaine may be adulterated with other substances and this may make it particularly dangerous to inject.
There is some debate as to whether tolerance or withdrawal symptoms occur with regular use of cocaine or crack. While it is true cocaine and crack are not physically addictive like heroin, it is misleading to define and therefore measure the existence of physical addiction using withdrawal symptoms associated with heroin. Each drug has it own unique physical effects, which in the case of cocaine amnd crack are very powerful. A chronic user of cocaine or crack will become very tolerant to the drug and their body also very used to the drug keeping them awake and functional. Once the user stops, which can prove very difficult for a regular or chronic user, they will very quickly start to feel tired, panicky, exhausted and unable to sleep, often causing extreme emotional and physical distress. This can manifest itself in symptoms such as diarrhoea, vomiting, the shakes, insomnia, anorexia and sweating, which for some can prove unbearable. Many chronic users are well aware of these symptoms and, in an attempt to avoid them as well as ensuing fatigue, are very reluctant to stop its use.
As far as crack is concerned, claims have been made that, unlike cocaine, it is instantly addictive making occasional or intermittent use impossible. Certainly, crack appears to induce an intense craving in some users which can rapidly develop into a 'binge' pattern of drug use. However, studies of people who have ever used crack show that nowhere near all go on to daily, dependent use and that when this happens it usually takes a few months. To become a dependent user of cocaine hydrochloride would usually take longer.
For both crack and cocaine, dependency is not inevitable. Whether people become dependent, and if so how quickly it happens, will vary depending on the individual user's mental state and circumstances. The fact that cocaine and crack are expensive means that people who become dependent may spend vast amounts of money. Those who are not wealthy may find themselves involved in crime or prostitution to fund a habit.
With everyday use restlessness, nausea, hyperactivity, insomnia and weight loss may develop. Some regular users become very 'wired' and paranoid. Lack of sleep and weight loss may lead to exhaustion and being very run down.
"Everyone who tries crack will not like the high and everyone who likes the high will not become instantly and hopelessly addicted." - M.G. Beattie, Crack: the facts. Hazelden Foundation, 1987.
"The first hit is always the best...I've never had anything like it. With crack once you've got that hit of the day, no matter how much you take you don't get it back. If the rock is there, I can't leave it, even though I don't get anything off it. But you can't just have one (rock) and leave it, you've got to have more". Quoted in Crack and cocaine in England and Wales. Home Office 1992
Repeated snorting of cocaine damages the membranes which line the nose. Repeated smoking of crack may cause breathing problems and partial loss of voice. Long term injecting may result in abscesses and infection with the added risk of hepatitis and HIV if injecting equipment is shared.
Pregnant women who heavily use cocaine or crack may experience complications and find that their babies are adversely effected. Much has been made in the American press of so called 'crack babies' and although some babies of crack using mothers may be irritable, difficult to comfort and feed poorly the extent to which this happens has often been exaggerated.
related links:
Cocaine's Month long Hangover
A Cocaine Experiment: Time-of-Day and Hangover Effects
The Buffalo Theory
Last Exits:
Betty Ford Clinic


text: Help! I'm having tandem saddle issues. I've got a Terry Butterfly on my Terry single (Terry classic), and an old Terry Liberator on my symetry. Both these saddles are working fine for me. I've put a butterfly on the tandem, but I can not get comfortable. It seems I have to sit more upright, there is no way around it. The seat won't go any farther back, and if I lower the handlebars any more, my nose will literally be in hubby's crack (he's a foot taller than me, so I'm pretty much staring at his lower back/butt as it is). So, I'm sitting up more, and depending on the adjustments, I'm either in sit bone pain, or we make some changes and I get full-on numbness. Any ideas, or saddle suggestions for the more upright position?


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For today's businesses the use of software is not a choice; however the methods chosen to improve software security and, in turn, the costs involved and the benefits achieved are. Using the right mix of approaches at all stages of the software development procurement and deployment life cycle will improve the efficiency, reliabilty, security, compliance and competitiveness of business processes.
Download Paper (Registered Members Only)
By downloading you agree to our Terms and Conditions. These include information regarding use of your personal data.


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This is part of a Microsoft Research study about how we can get regular people to do simple tasks at specific locations. This offer is only valid for people who have received an offer from Microsoft Research on Twitter.
For this task, we want you to take a picture of the sign on the front of the Bridle Trails Red Apple Market, whose address is 6625 132nd Ave NE, Kirkland, WA 98033, shown on the map at the bottom of this page. You should take a full frame picture (no cropping) like the example below.
Email your picture and Twitter username to firstname.lastname@example.com. We will check the picture to make sure it's right and also check the picture's embedded time stamp to make sure it's recent. If everything is OK, and if we've received your picture by the deadline we gave, we will reply to your email with an Amazon gift code with the amount we offered. You can apply the code to a future purchase from Amazon.com.
Red Apple Market from a distance (near center of picture)
Closer view
Example of type of picture we want (but without watermarks)


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Our locations
Phone: 206-296-4600
TTY Relay: 711
Toll-free: 800-325-6165
Click here to email us
Instructions to submit a Public Records Request
Instructions to
report a concern
Help us fight West Nile virus! If you see a dead bird in King County, report it through the Washington State Dept. of Health's online dead bird reporting website.
See photo-illustrated Bird Identification Gallery for names of birds.


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Jerry Wants You To Go Green
It's Earth Day. This video is charming because of the messengers, but the message hasn't changed in 23 years. This is the only planet we've got; there's no reason not to take care of it.
"Somebody has to do something…it's pathetic that it has to be us" – Jerry Garcia
More information about this video and The Dead's participation in it can be found at greenopolis.com.


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The ratios for our infant program are as follows:
Infants ages 6 weeks to 12 months have a 4 to 1 ratio.
Infants ages 12 months to 18 months have a 5 to 1 ratio.
The ratios for our toddler program are as follows:
Toddlers ages 18 months to 2 years have a 6 to 1 ratio.
Toddlers ages 2 years to 3 years have a 8 to 1 ratio.
The ratios for our preschool program are as follows:
Preschoolers ages 3 years to 4 years have a 12 to 1 ratio.
Preschoolers ages 4 years to 5 years have a 14 to 1 ratio.
School age kids 5 years to 8 years have an 18 to 1 ratio.
Conviently located in Chamipion, Howland, and Boardman, Ohio, The Kiddie Daycare is a short drive from just about any location.
Mention you visited our website during your tour and we will waive your enrollment fee!
Kiddie Day Care & Preschool will offer a Christian atmosphere for children to learn the fundamentals of life. Our staff will become an extended member to the families involved. Our center will be staffed with teachers that can offer the best care for the children and families. All staff will have training in C.P.R., rirst aid, child abuse, and communicable diseases.
1. We will operate the center under the Biblical beliefs..."Train up a child in the way he should go. When he is old, he will not depart from it." Proverbs 22:6
2. To provide teacher and/or child directed activities.
3. We will offer a style of learning where the child may learn at his/her own speed.
4. We will encourage different activities to best suit the families interest and needs.
5. Our centers will operate with trained and educated teachers.
6. We will open our doors to meet the needs of the families; we will have an open door policy for the parents.


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|START Conference Manager
(Submission #39)
Information-seeking behavior of academic scholars has been the focus of inquiry within the library and information science community for decades. The vast majority of user studies carried out in developed countries are well documented and widely known. There were only a few studies on information needs and information seeking behavior of scholars in developing countries. This poster presents the preliminary results of the study on information needs and information seeking behavior of Mongolian scholars, which was conducted in the summer of 2006. It presents the design and the first set of findings of a mixed method study intended to identify information needs and information seeking behavior of Mongolian scholars and explore options for meeting these needs. Specific goals of the inquiry are to determine how they find necessary information about the latest advances in their respective disciplines and that supports their research tasks; their preferred format for the literature to appear; the language they prefer the literature to be in; what services and resources they expect from libraries; what barriers they encounter to get necessary information for their research activities. In-depth interview and survey were used as the main research methods for this study. 17 researchers from various research institutions from the Mongolian Academy of Sciences were interviewed and 134 researchers responded to the survey. To increase reliability of the study, about 15 librarians were interviewed about the usage of library and resources by Mongolian scholars.
[Paper (DOC)]
|START Conference Manager (V2.54.4)
|Maintainer: firstname.lastname@example.com


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View From The River: After a year in life of Bryan, some Fulham fans still don't know talent when they see it
14:21 12 November 2012
EMPICS Sport
"He doesn't run enough."
"Personally, I will happily cope with a player not sprinting after every single lost cause if he can do what Ruiz does"
"He should be stronger there."
"He didn't even challenge for the ball there."
These are the types of comment I've heard around me at Craven Cottage about Bryan Ruiz in the last 12 months or so. Ever since his debut against Blackburn last year people have continued to cast doubt on his abilities to cope with the rough-and-tumble of the Premier League.
This is all complete rubbish. Five assists already this term (equal top in the league) along with 11 key passes and the Costa Rican is well on the way to coming good.
About our blogger
Name: Ben Walker
Twitter handle: @Walks11
Season ticket holder in the Hammy End
Favourite player: Current - Brede Hangeland. All time – Barry Hayles
Most memorable game: Fulham 4-1 Juventus, March 18, 2010 - It had to be didn't it...
Predicted finish: 8th
Watching Ruiz and Berbatov together is joy to behold at the moment and whilst Berba has had a plethora of justifiable praise for his immediate impact, the former also deserves his fair share of the spotlight.
I'd be the first to admit that Ruiz had a mixed first season and it took him a while to adapt after his move.
When he was beginning to find his feet, a broken foot curtailed that progress, but we saw glimpses of his quality when two stunning goals and a few assists showcased his talents.
However, the same opinions stuck and even despite his good start to this season some of the negativity can still be heard from certain sections of the Cottage crowd.
It is a particular English obsession with praising hard working players over a more languid quality on the pitch. Fans will love players for ever, even with limited quality, if they seem to give their all on the pitch.
Personally, I will happily cope with a player not sprinting after every single lost cause if he can do what Ruiz does.
Rooney is a classic example of this. At his best he is a great player but when it's not happening he goes chasing after the game, popping up all over the place to try to win the ball back and starting attacks even in his own half.
It looks great for people judging his work ethic but it means he isn't always in an advanced enough position to make a decisive impact on the game.
Bryan looks notably stronger on the ball this season and the new role playing off Berbatov seems to be really suiting him.
I appreciate that his style means that he will not be everyone's cup of tea and when we aren't playing well then he is an easy scapegoat. However, I love watching us play at the moment (although not watching us defend set pieces) and a massive part of this is the partnership that Berba and Ruiz are forming.
Long may it continue.


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Explore Asheville Music Venues – Diana Wortham Theater at Pack Place
Asheville is the music capital of the southeast
Diana Wortham Theater at Pack Place
At the center of Asheville's vibrant downtown arts scene is the city's finest theatre, offering the best in live performances of music, theatre and dance throughout the year by professional touring and regional arts groups. The intimate, 500 seat theatre is surrounded by numerous restaurants, museums and galleries, the Diana Wortham Theatre is at the heart of the Pack Square Cultural District. The theatre is home to the Asheville Lyric Opera, Asheville Ballet, Terpsicorps Theatre of Dance, Asheville Puppetry Alliance, WNC Jazz Society and many others offering diverse arts and entertainment programs throughout the year.
From I-240, take Exit 5A/Merrimon Avenue and follow the signs for Hwy. 25-South for three blocks to Pack Square, marked by the Vance Monument. For GPS systems use 2 South Pack Square for main entrance, or 12 Biltmore Avenue for Parking Garage. <p> From I-40, take Exit 50 (Hwy. 25) and continue on Hwy. 25-North through Biltmore Village for three miles to Pack Square.
Meeting Planners:
Please contact our Meetings & Conventions staff for more information about this meeting facility.
Call or visit the Web site for schedule.
2 South Pack Square
Pack Square Cultural District
Asheville, NC 28801
Attraction Amenities:
- Handicap Accessibility
- Parking (Fee Charged)
- Public Restroom
Discounts & Packages:
- Discount For Groups
- Discount for Seniors or AARP
- Beverages Available
- Admission Charge
- Reservation Available (Please Call)
- Reservations Required for Groups
General Contact:
Phone: 828-257-4530
Fax: 828-251-5652


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See All Contributors »
Tuesday night 9 pm ESPN. Who you got?
You live in Kansas City. Think you dumb ape.
Hopefully kansas blows them out, im all for big 12 winning as long as it's not against us.
Tough call. I think I'll take Kansas though. Wayne Selden Jr and Andrew Wiggins are going to be high draft picks this year. Add in their experience from last year + Bill Self coached team and they're going to be yet again down right dangerous. It'll be close though. Hoping Kansas gets the W.
Originally Posted by RollsRoyce
Tuesday night 9 pm ESPN. Who you got?
Duke. KU still young and learning. In a month or so KU will be in beast mode.
Duke looked fantastic in their opener. Rodney Hood was a man. They have so many options. I think they have the upper-hand early on the young studs from Kansas. KU will be much, much better come Big 12 time.
I will never root for KU, go Dukie!
Both are on my "strong dislike" list, but I respect the hell out of Coach K.
That and I will never, ever cheer for Kansas. Ever.
Kansas, need Big 12 to be as good as possible with the bottom so bad. Won't bother me if KU wins every game in the non-con and goes 0-18 in conference play.
Originally Posted by cymac2408
I will never root for KU, go Dukie!
I'm not rooting for either until i see the point spread.
They are both really young. I think on a neutral court this game is a toss up. The double header Tuesday is great. I'm interested to see how the refs call the games. It has been very uneven so far with some refs calling everything and making the games ugly and other games the refs are doing a good job of calling the new rules but not going crazy.
Other Big 12 teams winning is good for us and our SOS
If it helps Kansas' RPI come March, and therefore looking better on Iowa State's resume come March as we have 2 and possibly 3 wins against a Top 10 RPI from beating Kansas. I have to go with Kansas.
Originally Posted by Cydkar
I'm not rooting for either until i see the point spread.
Duke favored by 3.5.
Screw KU.
The smug condescension we received after the Hilton screwjob from their fans put me in the root for anybody over KU category.
Those of you who visited Phog.net after that game know what I mean.
I want KU to win for SOS reasons, but I think Duke wins by around 10-12
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Wrestling Forum : WWE, TNA, Indy Wrestling, Lucha Underground, Women of Wrestling Forums (http://www.wrestlingforum.com/forumindex.php)
- Classic Rants (http://www.wrestlingforum.com/classic-rants/)
- - Some of the guys on here are so pathetic (http://www.wrestlingforum.com/classic-rants/444915-some-guys-here-so-pathetic.html)
Some of the guys on here are so pathetic
Okay I've been wanting to say this for the longest time but I never did because I didn't want everyone to hate me and give me red squares but it got so bad that I barely even come here any more anyway so whatever I dont even care. Okay first of all let me say that there's a LOT of good posters on here and I love talking to some of you but there's even more fucking loser creeps on here. Some of the guys on here are just sexist perverts and I cant stand them, they're so annoying that they make me not even want to come here (which sucks because I love some of the people on here and I still wanna talk to them) but I hate how I cant make a post without some freak making a sexist comment either about how I should give them nude pics or about how I should be in the kitchen instead of posting, it's soo frustrating!
The thing that really made me mad was when someone gave me a green square for a picture I posted in the picture thread and the comment was "Your next picture better show more skin or next time this will be a red square." Wow, really?? Here's a better idea you fucking creep, get off the computer and go outside then maybe you wont have to harass an innocent girl on the internet for no reason. I come here to read wrestling news and have fun in the rants section not to be bothered by a bunch of horny virgin 12 year olds just finding out what their dick is for! News flash, the female posters on here are posters just like everyone else so why can't I just be treated like everyone else without all of these comments??
And sometimes I feel like I cant even totally blame the guys, some of the women on here are beyond pathetic. Like how can I expect to be treated with respect when there's e-sluts repping people with pictures of their ass or posting pictures of nothing but their boobs in the picture thread? You guys are even more pathetic than the guys but I feel more sorry for you guys than annoyed, that's beyond sad if you need to come onto a site full of horny guys and beg for attention because you can't get it in real life but sorry, I have a boyfriend who I love more than anything so I don't come here for that. I just want to read about wrestling and talk to the nice people on here and joke around and have fun, is that really too much to ask for?? Ahhh, that feels so much better letting that out, lol.
Re: Some of the guys on here are so pathetic
Nude pics coming soon, or no?
Re: Some of the guys on here are so pathetic
Didn't you say you had a dream about CM Punk fucking you and then saying it was like fucking a cake or something? That's pretty weird. lol
I don't really see people saying that kinda stuff on here. Just tell em to fuck off though.
Re: Some of the guys on here are so pathetic
I understand how that could get annoying some people are just desperate lol. Just ignore them and talk to the people that arent annoying.I think you could put people on the ignore list to.
Re: Some of the guys on here are so pathetic
It's your own fault for telling people you are a girl, tbf.
Re: Some of the guys on here are so pathetic
Good entertaining thread as usual. Honestly if I was a female I doubt I'd post on here, because sadly you get what you expect, and exactly the sort of people you would imagine posting on an Internet forum. Although I still say there are more good guys, than totally fucking perverts.
Re: Some of the guys on here are so pathetic
Nice location CBR.
Re: Some of the guys on here are so pathetic
Wanna make out?
Re: Some of the guys on here are so pathetic
There is no such thing as females on the internet.
Re: Some of the guys on here are so pathetic
I know how you feel, it's not easy being being extravagantly gorgeous on here.
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Farmer suicides in Chhattisgarh: A state in denial
Despite having the highest rate of farmer suicides per 100,000 population, the Chhattisgarh government is in denial. No one talks about farmer suicides in the state. As a result, the problem goes totally ignored, unlike other states like Maharashtra and Kerala
Manipur resists land alienation
250 farming families are protesting the acquisition of their fertile lands for modernisation of the Imphal airport.With cultivable land already at a premium in Manipur, the transition of agricultural land to infrastructure development all over the state will exacerbate the food crisis, add to poverty levels and cause loss of livelihoods
Revitalising agriculture in Kanjikuzhy
A decade ago, Kanjikuzhy in Kerala began to worry about the decline of farming. Then the community took the initiative to set up farmer groups and a distribution and retail network. Farmers and coir product manufacturers now get a fair price for their products and also bypass the middlemen
Nutritionist protests ban on lakhodi dal
Shantilal Kothari is fasting to have the ban on the cultivation and sale of lakhodi dal lifted. He maintains that lakhodi is an ideal crop for poor rural communities as it promises high yields, very low input costs and excellent nutritive value
Farmer suicides rampant in MP, Chhattisgarh too
A study by the Madras Institute of Development Studies puts the number of farmer suicides in Madhya Pradesh and Chhattisgarh at well over 2,000 a year. But both state governments are choosing to ignore the facts. In this report, farmers tell their own story
The SEZ versus the 'unrewarding' small farm
Kakinada farmer Narasimha Murthy's 5-acre farm supports 50 people, each living on around Rs 800 a month, more than twice the official rural poverty line.Why would farmers like him in 16 villages in Andhra Pradesh want to give up this livelihood for the Kakinada SEZ? What does the SEZ offer them anyway?
Industry vs agriculture: The battle over water in Hirakud
Before 1997, total allocation to industry of water from the Hirakud reservoir was 31,912 lakh gallons per year. In the nine years since, an 'allocation committee' has allocated 27 times more water to industry. This has, of course, been at the cost of water for irrigation
Call centres for farmers
Eighty-four call centres across the country are answering farmers' queries related to everything from fungus on brinjals to kisan credit cards and prices of insecticides
Food or fuel?
Bio diesel blends are driving buses in Haryana, Karnataka and now Pune. As bio diesel becomes the buzzword and corporates rush to develop jatropha and oilseed plantations, experts warn of adverse effects on biodiversity and food security
Taking the GE debate to the people
So far it's been multinational corporations, governments, CSOs and scientists who've been guiding the debate on genetically engineered crops. It's time to let people decide for themselves whether GE technology is safe, says Suman Sahai, convener of Gene Campaign


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Migraines & Headaches Health Center
News and Features Related to Migraines & Headaches
Forehead Lift Cures Migraine Patients
July 31, 2009 - Stacy Porter, 29, can't remember a time when she didn't suffer from crippling, relentless migraines before having the surgery that changed her life eight years ago. "I was diagnosed with migraines when I was 2 years old," the New Philadelphia, Ohio, marketing executive tells WebMD. "Read Full Article
Migraines Linked to Lower Breast Cancer Risk
July 9 2009 -- Women who experience migraine headaches have a significantly lower risk of getting breast cancer than those who don't suffer the headaches, according to a new study. The recent study is a follow-up to research published in 2008 that also found migraine headache sufferers have a signifRead Full Article
Migraines, Brain Lesions: New Links Seen
June 23, 2009 -- Women who experience migraine headaches with aura may be more likely to develop brain lesions when they are older, according to a new study. Researchers say the results add to a growing number of studies that suggest migraines may be more than a transient condition and may cause lonRead Full Article
Warm Weather May Trigger Migraines
March 9, 2009 -- Most migraine sufferers believe that weather changes can bring on their headaches, but the scientific proof has been lacking -- until now. New research suggests that certain weather conditions may trigger migraines and other severe headaches. But frequent sufferers may be surprisedRead Full Article
Closing a Heart Hole May Help Migraines
Feb. 16, 2009 -- Can closing a hole in the heart be an effective treatment for migraines? New research suggests that it may for migraine sufferers with a common heart abnormality known as a patent foramen ovale (PFO). But a researcher who has studied the issue for almost a decade tells WebMD that thRead Full Article
Belly Fat Linked to Risk of Migraines
Feb. 13, 2009 -- Belly fat has been linked to increased risks for heart disease and diabetes. Now new research suggests it may also be linked to an increased risk for migraines, at least until middle age. Waist circumference was found to be a better predictor of migraine activity than general obesitRead Full Article
Migraines May Cut Breast Cancer Risk
Nov. 6, 2008 -- Women who suffer from migraine headaches may be at significantly lower risk of developing breast cancer, a new study shows. "Many of the triggers of migraine in women are known to be hormonally related, and also are important in the development of breast cancer," Christopher Li, MD,Read Full Article
Janet Jackson's Vestibular Migraines: FAQ
Oct. 15, 2008 -- Janet Jackson has a "rare form of migraine called vestibular migraine or migraine-associated vertigo," according to a statement released by her publicists. Those migraines prompted Jackson to cancel several recent concert dates, but since then, she's gotten a thorough medical examinRead Full Article
Migraines Linked to Vein Blood Clots
Sept. 15, 2008 -- Migraine sufferers appear to be at increased risk for stroke, and now a new study may help explain why. One theory has been that people with migraines develop hardened plaque within the arteries -- known as atherosclerosis -- earlier than people without migraines. Atherosclerosis iRead Full Article
Magnetic Pulses May 'Zap' Migraine Pain
June 27, 2008 -- A lightweight, handheld device helps migraine sufferers zap away pain, sometimes within two hours, according to a new study. Called a transcranial magnetic stimulation device (TMS), it transmits magnetic pulses that interrupt the "hyper-excitability" of neurons in the brain, which sRead Full Article


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Nissan GTR DS2500 Street Compound High Performance Brake Pads - Front
- DS2500 Street Compound
- Front Set
- Street / Track Use
Mfg Part # : FRP3106H
Ferodo Brake Pads
Ferodo (a division of Federal-Mogul) has been making high quality brake pads from road cars to professional racing series since 1997. We are pleased to offer several options specifically from the Ferodo catalog.
Ferodo DS2500 - Street & Light Track Use
Ferodo recommends the DS2500 compound for high-performance street driving and occasional track day use. The good cold friction properties of this pad help it to respond quickly and predictably right out of the box. The DS2500 provides good driver feedback due to less compressibility. While able to take a good amount of abuse from lighter cars with moderate horsepower, For example the GT-R's power and weight (3,900 lbs.) will start to induce brake fade if pushed hard on the track (max. operating temperature = 950°F).
Ferodo DS1.11 - Track Use Only
Ferodo's DS1.11 Racing Compound is a new development based upon Siloxane Technology. This compound offers a constant friction coefficient across a wide range of temperatures and speeds for better modulation and higher confidence in the braking zone. Developed for extreme conditions, it features lower disc wear and better pad life than many race pads. When getting serious at the track, STILLEN recommends the DS1.11 compound for fade-free performance. This compound is for RACING ONLY and is NOT suitable for the street.
About Ferodo Parts & Accessories
Ferodo is the premium braking brand from Federal-Mogul. Our company has a proud history of technical innovation and product development. Today, we provide quality brake parts to the world's leading manufacturers and the aftermarket.
Federal-Mogul is an innovative and diversified $6.9 billion global supplier of products, trusted brands and solutions for braking, engine & sealing, steering and routine service parts. We serve manufacturers of automotive, light commercial, heavy-duty and off-highway vehicles, as well as power generation, aerospace, marine, rail and industrial applications.
Since the company began in 1899, we have celebrated countless victories and milestones as we lead the way in world-class automotive products. Today, we have 45,000 employees working across 34 countries, 103 manufacturing sites and 18 distribution sites.
Leading technology and innovation
We are passionate about progress and bold innovation has fuelled our success. Our 17 globally-networked technology centers enable us to bring breakthroughs in advanced technology and innovation to original equipment (OE) manufacturers and to the aftermarket. We have secured thousands of patents as we work to bring advanced technologies for cleaner engines and enhanced safety and comfort.
The Ferodo brand
Ferodo is a leading, internationally-recognized brand and favorite of the aftermarket. Our product range includes advanced technology brake pads, brake discs, lined shoes and brake fluids, as well as racing and high performance products and accessories.
- 2009 - 2012 Nissan GT-R


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As Congress, regulators and the plaintiffs bar increase their scrutiny of 401(k) fees, plan sponsors received a bit of good news late last month when a judge threw out part of a class-action lawsuit against Chicago-based Exelon.
The suit was one of a dozen similar class-action lawsuits filed by St. Louis-based law firm Schlichter, Bogard & Denton, alleging that companies violated pension laws by allowing 401(k) participants to be overcharged by the managers of the plans.
Other companies named in the suits include Lockheed Martin, Northrop Grumman, Boeing, General Dynamics, United Technologies, Bechtel Group, Caterpillar and International Paper.
In several of these suits, including the complaint against Exelon, plaintiffs claim that since the companies violated their fiduciary duties under the Employee Retirement Income Security Act, the employers should be liable for all investment losses that 401(k) participants realized.
The judge's dismissal came much to the relief of 401(k) plan sponsors, says Michael Crowley, associate general counsel at the National Futures Association, a Chicago-based organization for the futures industry with 249 employees and a $51 million 401(k) plan.
"If this had gone the other way, it would have been really bad for small plans with expenses much greater than ours because it would have meant employers were now insurers for their participants,"
The judge's dismissal comes at a time when 401(k) fees are top of mind on Capitol Hill.
On March 6 the House Committee on Education and Labor held its first hearing on the topic, and the Department of Labor has said that it will issue guidance next year to address fee disclosure. The issue, experts say, is that often employers don't know what they are paying service providers to oversee their 401(k) plans.
But to say that high fees result in investment losses is taking the argument a little too far, says Don Stone, president of Plan Sponsor Advisors, a Chicago-based 401(k) consultant.
"If the fees are high, then the fees are high, but that has nothing to do with investment losses," he says, noting that employers can't be held accountable for how the stock market performs.
While the judge's dismissal was good news for 401(k) plan sponsors, the issue isn't dead yet, says David Wolfe, a partner in the benefits practice of Drinker Biddle & Reath.
Schlichter Bogard, the plaintiffs' firm, can still revamp the complaint to better prove a causal relationship between fees and losses, he says. "Higher fees clearly reduce the rate of return on an investment, but the issue becomes whether that reduced rate of return is enough to show an actual loss," he says.
Jerome Schlichter, a partner at Schlichter Bogard, did not return calls seeking comment.


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Add happiness to the joyous event!
No baby gift makes the new parents more than our Happiness Baby Basket. This beautifully arranged and wrapped gift is overflowing with wonderful items for the new baby girl. The signature piece is a baby blanket decorated with our adorable "Happiness is....My Blankie" embroidery design. But that's far all that comes in this abundanly filledt baby gift. Happiness Baby Gift Basket includes:


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By Michael Collins
Body suits have been a big controversy going into this meet. I have been watching to see who is wearing them and who isn't. Here are some of my observations:
Full sleeves are not too popular.
Sleeveless with long legs seem to be popular with Freestylers and flyers.
Breaststrokers and IM'ers seem to use body suits the least.
People wearing body suits are not dominating.
Here's what some of the top athletes are wearing:
Full Legs and Sleeves:
Tate Blahnik
Sleeveless with legs:
Dara Torres, Jenny Thompson, Josh Davis, Courtney Shealy,
Sleeveless with knee length:
Misty Hyman, Amy Van Dyken, Tom Dolan, Lindsay Benko
"Bike" shorts (men only):
Lenny Krayzelburg, Neil Walker, Ed Moses, Gary Hall Jr., Tom Wilkens,
Traditional Suits:
Kristy Kowal, Maddy Crippen, Christina Teuscher, Megan Quann, Jenna Street, Amanda Beard, Staciana Stitts
For live results feeds check the OMEGA TIMING
Full results and schedule of events are available from US Swimming


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Humidity Control Van
A layout of the DHC Van is shown below. The interior of the DHC Van consists of two compartments: Zone 1 and Zone 2. An airlock separates the two zones. The airlock consists of a semi-transparent wall allowing visitors to see from one compartment to the other, and opposing egress doors for visitors to easily move between compartments while minimizing air exchange between the two zones. Zone 1 uses conventional air conditioning and Zone 2 uses an advanced desiccant-assisted air conditioning system.
Gary Capps, 865-574-2981
Kathy Gambrell, 865-946-1286


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I am evaluating WF for use in line of business applications on the web, and I would love to hear some recent first-hand accounts of this technology.
My main interest here is in improving the maintainability of projects and maybe in increasing developer productivity when working on complex processes that change frequently.
I really like the idea of WF, however it seems to be relatively unknown and many older comments I've come across mention that it's overwhelmingly complex once you get into it.
If it's overdesigned to the point that it's unusable (or a bad tradeoff) for a small to medium-sized project, that's something that I need to know.
Of course, it has been out since late 2006, so perhaps it has matured. If that's the case, that's another piece of information that would be very helpful!
Thanks in advance!


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The Real Purpose of Employee Reviews
Reviews can have some clear benefits if you do them on time.
July 21, 1999
The purpose of an employee review is not to 'fix' behavior once a year. If an employee has poor behavior, less than adequate performance or attitude problems, don't wait a year to fix them. Regular on-going coaching can not be replaced with an annual employee review.
There are a number of positive benefits to an employee review and there are number of disadvantages to not conducting routine reviews.
Advantages of reviews:
- They give the employee the opportunity to better understand expectations, standards and rules.
- They give the manager an opportunity to 'get to know' the employee better.
- They give the employee the opportunity to learn what behaviors and attitudes they need to improve or modify.
- They send a message to the employee that you care about their performance as well as them as a person.
- They can help you chart a better course for the future of the employee.
- They can help the manager identify weaknesses and strengths that may not have surfaced on a day by day basis.
Disadvantages of irregular or no reviews:
- They send a message that you are satisfied with performance, attitudes and behavior.
- They say to the employee they are not important enough for you to take the time for a review.
SOURCE: Tim Connor, Connor Resource Group, February 22, 1999.


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Arizona State (5-20, 1-13 Pac-12) – 19 • 29 = 48
Stanford (24-2, 13-1 Pac-12) – 45 • 26 = 74
• Stanford improved to 60-12 all-time against Arizona and completed the season sweep of the Wildcats with Sunday's 74-48 win. The win is also Stanford's 24th in a row against Arizona.
• Sunday's win clinched for Stanford a bye into the quarterfinals of the Pac-12 Tournament, set for March 6-9 at KeyArena in Seattle. Stanford also closes in further on its 14th straight Pac-12 regular-season title and 23rd overall, now leading the conference race by three games with four to play.
• None of Stanford's starters played more than 24 minutes Sunday. Amber Orrange led the five with 24 minutes played, while Chiney Ogwumike played 22, Lili Thompson 18, Mikaela Ruef 16 and Taylor Greenfield 13.
• Chiney Ogwumike's 22 minutes of playing time Sunday was her season low. Her previous low had been 23 minutes against New Mexico (Dec. 16) and at Fresno State (Dec. 28). She finished the game with 15 points and nine rebounds.
• Bonnie Samuelson hit five 3-pointers, just one shy of her career high, and scored 17 points to lead all players Sunday.
• Stanford went 13-for-22 from behind the arc Sunday, two days after failing to hit a triple against Arizona State. The 13 3-pointers marked the sixth game this year in which the Cardinal hit at least 10. Combined with the 15 3-pointers hit against Arizona on Jan. 17 in Tucson, Stanford has gone a collective 28-for-56 (50.0 percent) from behind the arc against the Wildcats this season.
• Amber Orrange scored nine points with nine assists Sunday, coming just one assist shy of her second 10-assist game of the season.
• Freshman guard Karlie Samuelson sat out Sunday's game with a sore foot. At the moment, she is expected to return to action in time for next Friday's game at USC.
• Arizona went 0-for-5 on its 3-point attempts, joining Gonzaga (0-for-14 on Dec. 14) as the only other team to fail to hit a triple this season against the Cardinal.
• Chiney Ogwumike's 15 points increased her career scoring total to 2,458, 33 points behind older sister Nnemkadi Ogwumike (2,491) for second place on Stanford's all-time scoring list.
• Ogwumike's nine rebounds Sunday brought her Pac-12-leading career rebounding total to 1,437.


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May 24, 2016
Howard Middle School carries more than 50 years of heritage, and some Jefferson County residents are worried it may soon be lost.
"This is a school, our heritage we have a lot of ancestors that has went to that school. I went to that school personally," said Carolyn Hamilton.
Over the years not enough people attended HMS and that was a major reason why the school closed down last year, but residents said it has not outlived its usefulness.
"I simply asked them to look at the feasibility of utilizing the closed Howard middle school as an elementary school," said David Cash.
With Jefferson Elementary enrollment up 75 students, reopening HMS has become a real possibility.
"The programs that both of our principals plan to put together for both of the schools that we are going to increase enrollment at both schools and we just anticipating students to remain in this county and some to return," said Shirley Washington, a Jefferson County School Board member.
Whatever decision is made on how to utilize HMS, the superintendent said the school board will do what's right for the students.
"It will be made in the best interest in how we can serve our students and in the most safe, clean environment that is possible," added Phil Barker, Superintendent of Schools for Jefferson County.
The school board plans to make a decision on how to utilize Howard Middle School at their next meeting, February 12.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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@Inproceedings {export:75598, abstract = {
Methods for expanding the dynamic range of digital photographs by combining images taken at different exposures have recently received a lot of attention. Current techniques assume that the photometric transfer function of a given camera is the same (modulo an overall exposure change) for all the input images. Unfortunately, this is rarely the case with today's camera, which may perform complex nonlinear color and intensity transforms on each picture. In this paper, we show how the use of probability models for the imaging system and weak prior models for the response functions enable us to estimate a different function for each image using only pixel intensity values. Our approach also allows us to characterize the uncertainty inherent in each pixel measurement. We can therefore produce statistically optimal estimates for the hidden variables in our model representing scene irradiance. We present results using this method to statistically characterize camera imaging functions and construct high-quality high dynamic range (HDR) images using only image pixel information.}, address = {Washington, DC}, author = {Chris Pal and Richard Szeliski and Matthew Uyttendaele and Nebojsa Jojic}, booktitle = {IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'2004)}, month = {June}, pages = {173-180}, publisher = {IEEE Computer Society}, title = {Probability Models for High Dynamic Range Imaging}, url = {http://research.microsoft.com/apps/pubs/default.aspx?id=75598}, volume = {II}, year = {2004}, }


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Sughran's Group
Sughran and her husband have three sons. The oldest makes a living selling milk and yogurt from a shop in the local market and the other two are still in school. She has applied for a loan which her husband will use to buy fresh seasonal fruits in bulk from wholesale markets. She believes that this loan will help her husband earn more money and operate his business more efficiently.
For the last nine years, Sughran and her family have lived in a two-room brick house in a small city named Khanewal. She is a member of Asasah and this is her third loan request. She paid her previous loans on time.
Additional Information
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Pakistan
246View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 13 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Oct 18, 2010
- Listed
- Oct 28, 2010
- Currency Exchange Loss:
- Possible
- Ended:
- Oct 15, 2011


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PORTLAND, Ore. (AP) — The Oregon Court of Appeals has affirmed a lower court's decision to commit a diabetic man with bipolar disorder to a mental health facility despite the man's insistence that God will protect him from the consequences of refusing to take his insulin.
The 23-year-old man identified as "C.C." was filing an appeal to his involuntary civil commitment.
Diagnosed with Type 1 diabetes when he was 14, C.C. began to tell family and friends in 2010 that he was hearing the voice of God in his mind.
He stopped taking his insulin soon after and his family noticed "explosive" behavior. He says he understood the risks of not taking insulin if he didn't have divine protection.
C.C. says he feared his parents' attempts to intervene were the work of the devil.


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The Reno-Tahoe Senior Winter Games
Do your athletic abilities get better with age? Are you in denial that you qualify for the "senior" group? Does the phrase "friendly competition" get your adrenaline flowing? If you answered yes to any of these questions, whip out those spectacles and keep reading…
The Reno-Tahoe Senior Winter Games is a program dedicated to promoting and implementing fitness programs and activities for people 50 years and older. Participants compete within age groups to win gold, silver, and bronze medals. The games include ski racing, table tennis, pickleball, baggo, poker, bowling, ice skating, hockey slap shot, snowshoeing, and cross country skiing.
The events take place February 4-14, 2013 at Harrah's Hotel and Casino, Sky Tavern Ski Resort, Mt. Rose Ski Resort, High Bowling Sierra Lanes, and the Rink on the River.
The cost of participation is $20 before January 25, $30 after January 25. The participation fee includes the cost of the Reno-Tahoe Senior Games competition bib, entrance and dinner at the Valentine's Day dance, and a Reno-Tahoe Senior Games t-shirt. In addition to the registration fee, each competition event has a $10 cost, except for cross country skiing which is $15. For more information or to register, please call (775) 344-2262 or visit www.reno.gov/seniorgames.


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Hoard's Dairyman Webinar Series
Barn design for robotic milking
presented by Jack Rodenburg, Ontario Ministry of Agriculture, DairyLogix
Brought to you by Lely
The ideal robotic milking barn optimizes cow comfort by providing low-stress robot access. It also offers practical space for special needs cows and convenient animal handling. Rodenburg worked for the Ontario Ministry of Agriculture – Extension Service and now operates DairyLogix.
Feeding for hoof health
presented by Mike Hutjens, University of Ilinois
Brought to you by Zinpro Performance Minerals
Register by clicking here or on the webinar title.
The Hoard's Dairyman webinar series is brought to you by Hoard's Dairyman and Mike Hutjens of the University of Illinois. They are held the second Monday of each month, and broadcasted from noon until 1:00 p.m. central time. Once registered, you can join the webinar up to 15 minutes ahead of the start time. This will allow you time to check for sound levels and screen dynamics.
Hosted by the energetic Mike Hutjens of the University of Illinois, each one-hour webinar will include nationally known and carefully selected presenters who will discuss the most timely and relevant topics and challenges faced by dairy producers today. Topics will cover input costs, finance, nutrition, milk quality, herd management, and milk marketing and dairy policy plans. All of the webinar topic areas are not finalized; this will allow for the addition of time-sensitive topics to be added. Your suggestions on topics are certainly welcome.
The webinars are designed to be interactive. If you have questions during the presentation, they can be typed directly to the presenter, and everyone can learn from the response and discussion. Polls can be conducted during the webinar to give the presenter a sound understanding of his or her audience demographics.
Our webinars are now approved for continuing education units (CEU) from the American Registry of Professional Animal Scientists. Each hour-long webinar will earn one CEU.
There is no cost to register or view the webinars. Once registered, you will receive e-mail reminders of the webinar date and time. If unable to attend a webinar, they will be recorded and can be accessed later.
Thank you for your interest in Hoard's Dairyman Webinar Series; and we look forward to you joining us on the second Monday of each month - just one hour. And you won't even have to leave the office.
presented by Mike Hutjens, University of Illinois
2nd Place, AAEA webinar:
"Winter strategies to enhance teat health and milk quality"
presented by Leo Timms, Iowa State University
3rd Place, AAEA webinar: "Help your dry cows avoid heat stress"
presented by Geoff Dahl, University of Florida
3rd Place, AAEA webinar: "Cows and their calcium"
2nd Place, AAEA webinar: "Five keys for reproductive success"
3rd Place, AAEA webinar: "Consistent, efficient TMR feeding"
presented by Paul Fricke, University of Wisconsin-Madison
Brought to you by: Parnell
presented by Bill Weiss, The Ohio State University
Brought to you by: Kuhn North America
presented by Mike Brouk, Kansas State University
Brought to you by: Dairy Nutrition Plus
presented by Amelia Woolums, D.V.M., Mississippi State University
Brought to you by: Dairy Calf and Heifer Association (DCHA)
presented by Mike Hutjens, University of Illinois
Brought to you by: Lallemand Animal Nutrition (www.lallemandanimalnutrition.com)


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Escort Services, Pittsfield, MA
Friendly Carwash
315 W Housatonic St, Pittsfield, MA 01201
1.0 Miles
"my grandson and love to drive thru your carwash it smells minty and is environmentally frie...">
Flavours Of Malagsia F F
Serving Pittsfield, MA
1.3 Miles
"I've eaten here often and have never been disappointed. Love the idea that you can select (s...">
Olson Nursery School
1956 East St, Pittsfield, MA 01201
4.3 Miles
"I loved Olson Nursery School for both of my Children. The layout is perfect for all learning...">
Berkshire House Cleaners
135 View Dr, Pittsfield, MA 01201
4.5 Miles
"We have had these ladies clean our home in Lenox for the past 6 months and they are amazing ...">
O'Laughlin's Pub
342 Merrill Rd, Pittsfield, MA 01201
3.4 Miles
"O's is a great place to grab a bite to eat or have a drink. The prices are reasonable, the ...">
Chiropractic Works
197 South St Ste A-9, Pittsfield, MA 01201
6.8 Miles
"Dr. Garber is kind, caring, healing, and passionate about his patients. This is chiropractic...">
Fontaine's Auction Gallery
1485 W Housatonic St, Pittsfield, MA 01201
2.6 Miles
"Great auction house. I have been buying and selling antiques at Fontaine's for over 20 years...">
174 South St, Pittsfield, MA 01201
1.4 Miles
"Most expensive place I have ever experienced.. staff must be paid on commission. A $27 part ...">
Berkshire Fire Place Pool & SPA
1402 North St, Pittsfield, MA 01201
2.6 Miles
"We bought a HearthStone Clydesdale (8490) woodstove insert. We love the stove but the blower...">
Avid Sports
1201 W Housatonic St, Pittsfield, MA 01201
2.0 Miles
"We took arrows to them to be reknocked and have new fletching put on. We left 7 arrows with...">
Jeans Cleaners
324 North St, Pittsfield, MA 01201
1.3 Miles
"Horrid service in every possible way. "Jean" is rude to repeat customers. The qual...">
Crowne Plaza Pittsfield-Berkshires
One West St, Pittsfield, MA 01201
1.3 Miles
Pittsfield Pipers Inc
73 4th St, Pittsfield, MA 01201
1.7 Miles
Pittsfield Auto Repair
866 East St, Pittsfield, MA 01201
2.2 Miles
Tire Warehouse
316 W Housatonic St, Pittsfield, MA 01201
.9 Miles


text:
- 5 years ago by Jessica P. Ogilvie
- 8 Comments »
- Share a Tip
Scientists have discovered that beluga whales are nudists when it comes to humans; the Daily Mail reports that the giant sea mammals don't like being touched by "artificial materials" like diving suits. That's why when Russian scientist and diver Natalia Avseenko, 36, decided to swim with them, she agreed to strip down completely naked. More


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Health and Safety Policy - Statement of Intent
It is the policy of Lancaster University to ensure, so far as is reasonably practicable:
- the health, safety and welfare at work of all employees.
- that those not employed but who may be affected by the University's work activities, such as students, visitors and contractors, are not exposed to avoidable or unacceptable risks to their health and safety.
- that articles and substances are used, handled, stored and transported safely.
- that appropriate health and safety information, instruction, training and supervision is provided.
- that safe plant and systems of work are provided.
Further, it is the policy of Lancaster University:
- to provide and maintain appropriate procedures for action to be taken in case of fire and other emergencies, including injuries and dangerous occurrences, and for their effective reporting and recording.
- to provide and maintain procedures for consultation with all employees on any measures at the workplace which may substantially affect the health and safety of employees.
- to develop and maintain a high degree of safety consciousness and positive attitudes to health and safety throughout the University.
Professor Mark E Smith Vice-Chancellor March 2012
Last updated: date


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December 5, 2013 8:45 AM
New Wave staff
"We have a social mission, but we also think we can be self-sustaining. Students feel it and understand it, and I think that makes them better attorneys," says Elizabeth Townsend Gard, who hopes to launch Durationator this academic year. (Photo by Paula Burch-Celentano)
Tulane University, New Orleans, LA 70118 504-865-5000 email@example.com


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Cant quite understand why people think Rossi is over the hill when he is only 34!
Biaggi won the WSBK title at 40!
So did Bayliss if i recall.
You have to look at things logically.There are only 4 bikes on the grid capable of winning races and Rossi is on 1 of them.He therefore has a 1in4 chance of winning every race.That means he should theoretically win at least 4/5 races this season.If his opposition crash out or miss races through injury,those numbers could well go up.So of course he has a chance at the title.You would be foolish to rule him out.


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Rob Bliss has been involved in the California underground music scene since 1996. Paying tribute to the history of global sound system culture, his energetic, bass-heavy DJ sets often bend genres and incorporate dazzling scratch routines.
He's held residencies from San Francisco to Los Angeles and built a solid reputation over the years. His selections explore the deep spectrum of urban music, bringing together jungle, garage, hip hop, dub and soul influences.
Press play to try again.
You can get it here.


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Move aims to encourage companies to follow best international practices; violators to be penalised
After tax audits and mandatory corporate social responsibility norms, the government is set to introduce water audit and yearly water footprint disclosures in annual reports a mandatory feature for companies. The move is aimed at encouraging companies registered in India to adopt the best international practices on water use efficiency.
A senior official said the idea is to make it mandatory for companies to disclose the volume of fresh water used by them in their production activities and the volume of recycled water use per year. Firms will also have to commit themselves to timelines on reducing their water footprint. This would be implemented through the corporate affairs ministry soon, said the official.
The corporate water footprint is defined as the total volume of fresh water that is used directly or indirectly to run and support a business. The water footprint of a business consists of water used for producing/manufacturing or for supporting activities, and the indirect water use in the producers supply chain. This will now have to be disclosed every year in the companys annual report.
On the corporate side, companies have already committed to this initiative. Hindustan Unilever, for instance, has said it would look at saving 50 billion litres of water in the next four years through its new initiative, India Water Body. Others, including units of Ashok Leyland, Mahindra & Mahindra, Hindustan National Glass & Industries, Godrej Industries and ITC, have already adopted water auditing as part of their plant functioning, said a senior official in the Confederation of Indian Industries (CII).
While many companies are adopting water audit and water conservation as part of their work culture at their respective manufacturing units, a mandatory including of water auditing and disclosure of water footprint in annual reports will go a long way in making corporate India improve its accountability towards reducing waste of fresh water, said a CII official.
The government will also make comprehensive water audits a recurring feature of industrial activity. The water audit will consider both quantity and quality aspects of these industries. These measure will begin with the scrutiny of water use by large water-intensive industries, including paper and pulp, textiles, food and beverage, leather, pharmaceutical, oil and gas and mining, among others.
Now the government will work with industry representatives and industry bodies to work out the