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Local Matters (excerpts)
-The public schools are closed until further notice on account of the influenza
epidemic. It is noticeable that the school children are not running about in
droves on the streets during the unscheduled holiday which would seem to indicate
that their parents are keeping the youngsters at home and away from possible
sources of contagion, though measles and the grip have a lot of victims among
those of school age. The various churches and Sunday schools of the village
were also closed Sunday.
-The present epidemic of influenza is keeping a few available doctors on the
jump day and night. With Dr. Leary and Dr. Messer both unable to practice, the
two remaining Turners Falls physicians are unable to respond to all demands
made for their services. The Farren hospital corps of nurses has been badly
crippled by the disease- though the situation there is improving. Everybody
is praying for better weather, when it is thought the cases of illness will
The same day that the Greenfield, Massachusetts newspaper reported on the effects influenza epidemic in the neighboring town of Turners Falls, the town's newspaper included this short article. It states that the schools and churches are closed and that it is very noticeable that children are not out playing. This indicated that they were being kept at home, away from other people. The article also comments about the effect of the epidemic on the local doctors, nurses and hospital and that everyone is hoping for better weather so the illness would subside.
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See Also...
"Influenza Epidemic Continues" article in Gazette and Courier newspaper
"Graduated Medicine Spoon No. 40"
Dr. William G. Watt
"Influenza With Us- Epidemic Has Taken Hold of Greenfield" article from The Greenfield Recorder newspaper
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Nancy Drew
|Release Date: June 15, 2007
|Running Time: 98 mins.
|MPAA Rating: PG
|Box Office: $25,584,685.00
|Genre: Adaptation, Adventure, Crime, Drama, Mystery, Thriller
Emma Roberts
Tate Donovan
Barry Bostwick
Laura Elena Harring
All Cast & Crew >>
Summary:Nancy Drew, the resourceful teen detective, leaves her friendly hometown of River Heights for the West Coast and enrolls at Hollywood High School. There, her unique personal style immediately sets her apart from her self-absorbed, fast-living peers, especially reigning fashionistas Inga and Trish, who can't quite figure her out but know that everything about her is different--from her super-smarts and retro manners to her perfect picnic lunches and penny loafers. Their less-than-warm reception might bother the average new girl in town, but not Nancy. She has more important things to think about--namely, a brand new mystery. Even though she promised her worried Dad that she'd quit the "sleuth... Full Summary >>
Event Photos:

subset: commoncrawl


text:
NEW YORK (AP) — A judge has rejected a request to limit what New York Mayor Michael Bloomberg or top aides could be asked at a coming trial where a campaign consultant is charged with stealing more than $1 million from the billionaire mayor.
Jury selection was postponed from Monday to Sept. 19 for John Haggerty's trial. Bloomberg may testify. City Hall has declined to comment.
Prosecutors say Haggerty pocketed most of some $1.2 million he got Bloomberg to give the state Independence Party. The money was to finance poll-watching in 2009, when Bloomberg was running for re-election. Haggerty says he did nothing illegal.
Prosecutors had wanted the judge to bar Haggerty's lawyers from delving into Bloomberg's campaign finances. On Monday, the judge said no.


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REVIEW: Are You in On the Joke? "Idiots" Comes to America
by G. Allen Johnson
(indieWIRE/4.27.2000) -- Even before all this Dogma 95 nonsense, a Lars von Trier film seemed like an elaborate practical joke. Was he duping us or enlightening us? Oh, well, as long as we were entertained.
"Zentropa" (1991), for example, is a film best left unanalyzed -- you absorb it rather than experience it. Yet it remains one of the most visually inventive movies of the last 20 years -- an American (played by a Frenchman) goes to post-World War II Germany and discovers there are still Nazis out and about, all to the tune of Max von Sydow's hypnotic voice. "The Kingdom" (1994) and "The Kingdom, Part II" (1997) are his own "Twin Peaks," films so bizarre in nature it's best to just go out and rent them and see for yourself. He uses his camera like a dentist's drill, boring directly into his characters and unveiling their deepest quirks.
Finally, nearly two years after premiering at Cannes, his most audacious foray into hot-foot territory, "The Idiots" opens here in America, decidedly shorn of its manhood, thanks to the addition of superimposed black bars, but here nonetheless. Though it does not feature the confrontational power of past Danish works -- von Trier's own "Breaking the Waves" (1996) and Thomas Vinterberg's "The Celebration" (1998) -- "The Idiots," in Danish with subtitles, is perhaps more complex. As a viewer, you're never sure whether you're in on the joke.
"The Idiots" are a group of yuppie-ish people who go around in public acting retarded. They are duping the general public, observing reactions, celebrating their victories and, in the beginning of the film, getting their restaurant bill comped on the condition they get the hell out of there.
The idea, as Stoffer (Jens Albinus) -- the tall, handsome blond man who pushes the agenda of the group -- puts it, is to "discover the inner idiot in all of us." In other words, the tedium and predictability of everyday life is due to the fact we are cornered into a course of action by society, from jobs dictating our schedules to families dictating our time and attention. We all become, in essence, hammered into the same person.
By acting the fool, they are simultaneously waking up their joke victims and liberating their own feelings and emotions. A group discussion after the forays, such as at the restaurant or a visit to a factory, is a handy aid for analysis. "Society is getting richer and richer," says one member, "but not getting any happier."
At the center of this group, which is about a dozen strong, is Karen (Bodil Jorgensen), who has just joined because she "would have joined anything," as one person points out. It is implied that Karen's husband has left her, and she is at first horrified by the disrespect of being retarded, but quickly realizes how it can liberate her as well.
Also in the cult, for that's what it is really, are two attractive blond women, Susanne (Anne Louis Hassing) and Nana (Trine Michelsen), a boyish man, Jeppe (Nikolaj Lie Kaas) with obvious insecurities, and Axel (Knud Romer Jorgensen) who seems the most normal and actually holds down a job.
Sometimes they bully the people they are deceiving, as when a few of them go door-to-door collecting money to fight their "afflictions" and threaten to sue a homeowner whose cobblestones they have accidentally-on-purpose tripped over. At other times, they place themselves at the mercy of their "victims," as when Jeppe tries to befriend tattoo-laden bikers at a local pub.
Once, for experiment's sake, they invite a group of real retarded people to their estate. Stoffer, consistently the cruelest of the bunch, suggests they "gas them," and rushes to take pictures of them, though noting, "It's a pity we can't capture their genes on film."
As they go deeper into their own psyches and perpetuate the charade, it strains the group and drives some into a more disturbed state of mind. At times, it's not clear whether the inner idiots are turning into full-blown idiots -- being driven crazy by their own alter egos -- or still acting their part.
By now, Dogma 95 films -- which eschew any artificial manipulation of film, from photography to props (with the notable exception of editing) -- have to be taken very seriously. Like the French New Wave films of the late 1950s and early 60s, they have a distinctive visual look all their own and explore serious themes, mostly the deeper quirks of people and families who seem normal on the surface.
It's also remarkable how similar these Dogma films are, whether they're made by von Trier, Vinterberg or Soren Kragh-Jacobsen ("Mifune"). That's the point, though: the directors don't take official credit for their work, as that's a conceit outlawed by the Dogma 95 manifesto.
There's something interesting going on here, all right, even though there are stretches in all of these movies -- "The Idiots" included -- where it all seems so fake or overdone, from a hand-held camera jockeying for position for something as innocuous as revealing what someone is eating to a tendency toward contrived melodramatic moments when characters weep for little or no reason.
When a man comes to try and reclaim his daughter from the group, Stoffer, who is slowly cracking under strain of their escapades (or is he?), tells him "if you could see things differently you might see the beauty of (life)."
In a way, that's what von Trier, in the second half of his career, and his Dogma colleagues are doing. They're willing to play the fool for us in order to experiment with a new kind of cinema, a pared down vision in an increasingly CGI world. While von Trier's masterpiece, one suspects, will always be "Breaking the Waves," "The Idiots" is one tightly edited, intensely acted parlor game.
[G. Allen Johnson is a film critic for indieWIRE and the San Francisco Examiner. He has also written for the Bloomington Herald Times, Pasadena Star-News, Los Angeles Daily News and Indianapolis Star.]


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In the human eye, the fovea centralis provides sharp central vision by packing in a high concentration of cone photoreceptors and connecting about half the nerve fibers from the optic nerve onto those cones. This gives high definition to the center 2 percent of the visual field, providing detailed vision and allowing us to read and track clearly the most important objects in the visual field.
TACO, a mangled acronym squeezed from Three-dimensional Adaptive Camera with Object Detection and Foveation, is a European research project applying high-definition 3D vision of a small centralized area to enhance robot vision. The TACO camera will emulate the human eye to increase the resolution of a small central area of the viewing field, refining the focus area to important objects, speeding recognition time and visual processing speeds with a three to 10 times increase in spatial recognition and frame rate. Advances in robust yet low-cost hardware, and the software necessary to rapidly detect objects in the environment, drive the project that started in February 2010 and will run three years.
Want to learn more about our membership options? Give me a call.Leo Baryudin, Robotics Membership Manager
Expert insight on the ethical and legal issues affecting robot regulations globally.
The new reality of customizable, one-off production:
Additive Manufacturing (AM). Where it's going, why and what's
driving its emergence.


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On August 26, 2009, Boston's WEEI 850 AM became the official flagship station for the Red Sox, supplanting their sister station, WRKO 680 AM, which had aired Red Sox games since the beginning of the 2007 season. WEEI was the Network's flagship station from 1995 through 2006, after which time WRKO signed a 10-year deal with the Red Sox to be the flagship. Both WEEI and WRKO are owned by Entercom, who decided to make the switch since WEEI is an all-sports station while WRKO is branded as "Boston's Talk Station."
The announcers are Joe Castiglione, in his 31st year with the Red Sox, and Dave O'Brien, who is in his 7th year with the team. Sean Grande or Lou Merloni occasionally fill in for O'Brien, who misses a handful of games during the regular season because of his contract with ESPN.
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Minimum shear wind strength required for dynamic soaring of albatrosses
Version of Record online: 16 DEC 2004
DOI: 10.1111/j.1474-919x.2004.00295.x
Volume 147, Issue 1, pages 1–10, January 2005
Additional Information
How to Cite
SACHS, G. (2005), Minimum shear wind strength required for dynamic soaring of albatrosses. Ibis, 147: 1–10. doi: 10.1111/j.1474-919x.2004.00295.x
Publication History
- Issue online: 16 DEC 2004
- Version of Record online: 16 DEC 2004
- Received 23 July 2002; revision accepted 15 March 2004.
- Abstract
- Article
- References
- Cited By
The transfer of energy from the moving air in the shear wind above the sea surface to a bird is considered as an energy source for dynamic soaring, with the goal to determine the minimum shear wind strength required for the dynamic soaring of albatrosses. Focus is on energy-neutral trajectories, implying that the energy gain from the moving air is just sufficient to compensate for the energy loss due to drag for a dynamic soaring cycle. A mathematical optimization method is used for computing minimum shear wind energy-neutral trajectories, using a realistic flight mechanics model for the soaring of albatrosses. Thus, the minimum shear wind strength required for dynamic soaring is determined. The minimum shear wind strength is of a magnitude that often exists or is exceeded in areas in which albatrosses are found. This result holds for two control cases dealt with, one of which shows a freely selectable and the other a constant lift coefficient characteristic. The mechanism of energy transfer from the shear flow to the bird is considered, and it is shown that there is a significant energy gain in the upper curve and a loss in the lower curve. As a result, the upper curve can be qualified as the characteristic flight phase of dynamic soaring to achieve an energy gain.


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Support for her work has included grants and commisions by the Louisiana Endowment for the Humanities, the SURDNA Foundation of New York, the Joan Mitchell Foundation of New York, Louisiana Cultural Economy Foundation, Louisiana Division for the Arts, Houma Regional Arts Council from the Department of Culture, Recreation and Tourism in cooperation with the Louisiana State Arts Council and the Louisiana Division of the Arts and the Office of Cultural Development.
Artist Statement
Michel Varisco's large-scale photographs depict late-Louisiana in its accelerated shift towards the Gulf of Mexico. The photographs are pointers to the complex relationship between the natural and engineered environment carved out of a delicate delta system. As a native New Orleans artist, Varisco depicts her homeland through photography and installation to educate, inspire, transform and heal an ecologically and culturally rich place that's fighting to survive.
Shifting is a series shot before, during and after the BP Deepwater Horizon oil disaster, and examines the systems of land and water management that has caused a crisis of loss within a single century. Staying on houseboats, going into marshes with fishers and flying above the Gulf in small planes while working with scientists, Varisco documents first hand what is occurring in the Southeast Louisiana's wetlands and open waters. Nathan Martin writes of the work: "Contrary to what one might initially surmise, her photographs are not traditional nature or landscape photographs. They are photographs of functioning systems, and therefore photographs of events: the Mississippi shifting, the wetlands melting, human machinations encroaching on the natural world. A number of writers, such as Curtis White, have argued that the conversation about our ravaged environment has been hijacked by scientists, businesspeople, and politicians in such a way that the true essence—the spiritual essence, if you will—of nature's importance has been sidelined . . . Varisco's work steers the conversation about the environment back toward what is deeply and profoundly at stake."
Varisco writes: "I believe humans have the capacity to restore what seems permanently lost should our imaginations and ingenuity be so inspired. It's also my hope that we analyze the interconnectedness of these problems, as they face Louisiana, the United States and other lands around the world. We are at a critical juncture now. As an artist, I feel moved to create out of that collective anxiety of what we are doing to our planet, and by default, to ourselves."


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Photo Credit: Nicky Pallas via Flickr
Against all odds, yet again, by some means, the Chicago Bulls are here. 47-33; heading into the playoffs with home court advantage; and of course, Derrick Rose is sidelined. Aaaaagain.
Whether it's the banners overhead as the final remnants of a bygone basketball era or the crippling expectations that haunt all sports fans, fans have never taken well to the notion of "average" — as if there was something deplorable about consistently being in the playoff picture.
But after last season's "imagine how good they'd be with Derrick Rose" turned to "will he or won't he" plot, I'm learning to find silver linings in a losing battle. The story is the same this season as it was last: Wonky 6'11 stoner channels inner sports cliché while his coach guides team to improbable playoff run. It was like the first season of Friday Night Lights, except everyone was so busy wondering if Jason Street would ever walk again that no one noticed the Panthers won a state championship on the backs of Saracen and Coach Taylor.
Rose tearing his ACL sucked. That's about the only explanation there is. For a fanbase vaulted into mediocrity after hopes of contention, bad luck is a hard crutch to fall on. But my grievances were rooted more deeply in the entitlement of fandom than the randomness of fate. It's always been this: X years of suffering should lead to Y amount of joy. As a pretty decent television show once put it, though, "deserve's got nothin' to do with it."
This season, the limelight disappeared, along with speculation and expectations. There's no definitive Tom Thibodeau profile frolicking around the interwebs. No high-profile adidas campaign. Just a team and it's fans, writing their own story as the season progresses, learning to navigate the beauty of a team without the industry surrounding it.
At times, deep into a jet-fuelled third quarter with Joakim Noah on the brink of destroying the concept of what an All-Star center is supposed to be, I forgot Derrick Rose ever walked these halls. It's a different kind of alternate universe: the guy in a suit on the edge of the bench isn't a worn down MVP but maybe an assistant coach.
The Bulls don't seem concerned with #TheReturnPart2 either. They're busy rendering sports cliché true, so much so that it's become cliché to call Chicago cliché. The Bulls are one of few franchises in the NBA that are okay with not letting perfect be the enemy of good. Yes, satisfaction is the enemy of progress. But sports rarely allow us to think of it the other way around: Progress is equally the enemy of satisfaction.
That's not say that speculation and expectation are all bad. They exist because we want it that way, especially when it comes to our sports. They're an important part of the experience, an admission of full immersion. The things that make fandom worth it are the crux of our love and despair; prediction begets such a high level of willful involvement and emotional attachment that it's an explicit admission of insanity.
Besides, ignoring the present to analyze a vague future or obsess over the past is what humans do best!
Nobody will ever learn how to block out the amorphous concept of "what could have been", but Chicago is learning to live with it, taking joy in any silver lining that comes their way. Just as anyone who's had a TV series, a book or a movie spoiled knows, accepting the triumph of inevitability opens the gates to a wealth of freedom and enjoyment.
The playoffs are considered magical ground filled with a brand of optimism only a clean slate, 0-0, could produce. But 48 minutes in, every non-contender has one eye to the offseason. For owners and GMs, it makes sense. They have decisions to make and players to evaluate. The rest of us, and it's a sad truth, are powerless over the fate of our favourite teams
Why not step back, smell the roses (pun totally intended) and try to enjoy the ride? There are games yet to be won and lost and ripples yet to be discovered beyond the surface of whatever wins and losses are coming our way.


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Is thevibram five fingers australia Yi how can what he beats to come?" Cheap Beats By Dre The red rhyme a little bit puzzles of answer a telephone, walk to part.Led soon, the red rhyme came back."What matter?"Zhao Tie Zhu asks a way."This returns be really magic, we this just made reference to my university, I the leader of class in university time beat for me call, said enjoy a get-together."The red rhyme says with smile."You 30 many also make classmate party?""Can not?Don't think 30 many the person Be getting older, in fact we can still morally upright young!Party on this Saturday evening, at Long Teng hotel, I does this leader of class still make me take an I man, do you say that I want to take you to go?"The red rhyme charmingly femininely looking at Zhao Ties Zhu."This, with you then, I see to have time when the time comes."Zhao Tie Zhu says."Hum, still have to you sometimes you just go BE?That calculate, I seek a comparison to depend to compose of, affirmation can go."The red rhyme is cold to hum 1."If the oh, that is all right, when the time comes I am have no time, will also take time to keep what you go company."Zhao Tie Zhu says."You, can not take no cognizance me?"Traverse snow and looking at is beating two people whom the feeling scolds Qiao, a burst of band together, especially Zhao Tie Zhu, really make her feeling over completely whole Cheses thoroughly not understanding of the bottom, this person, time just fought, can be so brave, so dominant, then again very iron blood and Ao however, after behind and oneself gets on the car, and then become very trivial to lust for women, the person of like this multiple personalities, seem to be clear good dinner of a layer, just started maying make people don't adapt to,cheap monster beats but waited really and more after tasting severals, you will discover, so the layer was clear but again self-contradict thing, will make people unbearable to addict into.The in the mind that traverses snow starts to Zhao Tie Zhu and produced a little of curious, curious about Zhao Tie Zhu, why can so naturally convert in various role in each personality space, in the red rhyme in front, gentleness of and a little lover is general, but in oneself's in front, but is overbearingly imitate a Buddha the Chu overlord is similar, in enemy's in front, but is coldly imitate if fix Luo generally."Huming is indeed as expected a mental derangement."Traverse snow dark hum 1."Oh, Ling Xue, you is jealous?Ha ha, unimportant, the elder sister is getting older, this world is finally still your young man of, iron pillar is also still young, you opportunity to have plenty of.""Red elder sister Yun, you can be not old."Traverse snow to say with a smile, but is don't realize a making fun of of red rhyme words inside."The gosh didn't go, you see my daughter and all read Gao San all, am I still not old?"The red rhyme shook to shake head.Zhao Tie Zhu takes two women and turns head a rate to almost attain a hundred per cent all the way, a lot of girls were attracted to Zhao Tie Zhu, while the red rhyme and Ling Xue then have no to hang to read of drew on all boys attention.Spend more than ten minutes to walk to biggest assembly hall of FJ university, the assembly hall inside at this time, have already sat full person, Zhao Tie Zhu directly takes Ling Xue and red rhyme to walk to first row.The president of FJ university's waiting leadership in the school has already sat here."Iron pillar, congratulate you, ha ha."The president sees Zhao Tie Zhu and smile to nod to say "hello", although Zhao Tie Zhu's identity is very marvelous, in the whole school teachers and the students' in front, the president should have of act with dignity, or need of, so the president has never stood to start."Ha ha, all of this are the classmates, the teachers of of support."Zhao Tie Zhu's this fellow very will be a person as well, the nature isn't silly to force of peep out a very marvelous appearance to elder brothers."Iron pillar you didn't want condescension, these 2 BE??"The president imitates a Buddha to just see Ling Xue and red rhyme's appearance and curiously asks a way."These two friends who is me, I take them to come over to play, there is still seat having no here?Words of having no I allow them to sit the behind went to."Zhao Tie Zhu asks a way."You asked like this, having no the seat musted also have seat."President's in the mind the dark way is a , on the face but is have no what not good facial expression, but warmly say, " has, here seat much go to."Say words, the person of the president to the body side beat an expression of eyes, nature have that person who is good at ascertaining intent through word and expres,
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the station starts to say, " president, I this hasvibram five fingers some a matter and walked first.""H'm H'm, all right."The president also has no to request more to stay,cheap beats put a person to leave.The person, who is good at ascertaining intent through word and expres, is a not only, this person just talk, again someone stood, is also occupied and walked, this traversed snow and red rhyme of seat problem, a while solve."You sit here, I still have to go to backstage, Niang of, after a while still have to go up to walk to show, is whole life greatly so long, haven't walked to show."Zhao Tie Zhu has a little to awkward and shily say."Have no matter son, we can't smile yours."The red rhyme Wu mouth says with smile."That do you still smile now?""Now smiles first to arrive not to want to smile and after a while smiles not to come out."Red rhyme answer way."Is all right …" Zhao Tie Zhu the helpless Song shrug shoulders and turned round to walk into backstage.But there has been at this time, in the backstage many people, in don't lack handsome boy and beauty, Li Ling Er sits upright in a disguise mirror front, is drawing a makeup.Today's Li Ling Er is dressed in a thin aureate bunch chest evening dress, the show hair in a head of black covers with at shoulder up,beats by dre match with that kid Yan again, the whole individual seems to be to lure dint hundred percent, but that huge chest, is also bunch chest to support tightly, that together deep ditch, almost and deeply disappear bottom.Like a big ditch!Zhao Tie Zhu dark great 1, smiled to head for Li Ling Er."Work properly son, the evening is really beautiful."What Zhao Tie Zhu occupied vantage pointed looking at to sit to reign Li Ling Er who places the last disguise and sees into from this position, that gutters' seeming to be more is getting deeper."Xi Xi, that is a matter of course, the somebody else is a campus queen to come!"Li Ling Er sarcastically says."That am I also grass in the school!"Zhao Tie Zhu gets saying of Se."To, you hurriedly turn a makeup to go."Li Ling Er says."Where did you turn it ?""Here!"A effeminate voice rings out.Zhao Tie Zhu follows reputation to go to, not from greatly sigh a , I Lei go to!Chapter 856 works properly son to help a disguise[this chapter word number:2133 latest renewal time:2011-11-2012:00:00.0] is in the moment pretty much soft United States being a…man ….Yes, Zhao Tie Zhu make sure at present this person, is a man, but, his foppery and talk of tone action, all heel a woman generally have no two, even in, he is Beats">http://www.edocrazy.com">Beats By Dr Dre Mixr getting more beautiful than the general woman.That powder delicate powder delicate Qiao face up, be beaten last 1 F light foundation cream,cheap beats by dre seem to be the whole face Be getting more pure white, on the oval face of standard, a rightness of Feng eyes gleam moving, but that almost grows the long hair of loins, drive he to weave a horsetail plait similar thing, most give dint of BE, the bitter end in that horsetail plait, there is also a bowknot of pink.This person's clothes over there, the last body is a long sleeve of woolens and flannel, a very small V gets, and the clothes inside has a very small scaled bra!Yes, everyone didn't see wrong, is a bra!!Different from bad omen in"benefactor top of head bad omen" bra!Zhao Tie Zhu really wants to ask him, Ni Ma you don't have that trick, how still not bashful wear a bra?Ni Ma you wear and then wear, why and must wear a C cover cup of, you this is to place the girl whom numerous A.Bs cover a cup in where!!Is all right, even if is a C cover cup also doesn't matter, Ni Ma you why still inside you fill of the cotton peep out a let somebody else see, you is this to want to tell everyone that you in fact have no chest?See that again body, Bohemian long skirt of a powder color, Zhao Tie Zhu originally is pretty much liked Bohemian long skirt, but why Zhao Tie Zhu saw this Bohemian long skirt today, will have a kind of felling that is suffused with Ou?Especially under that long skirt of feet, Ni Ma is that a high-heeled shoes?And still that kind of sandals the similar high-heeled shoes is also Tu Zhu's some colors on toe A."This is …?"Zhao Tie Zhu tooks a look Li Ling Er, and then sees for a while in the moment this strange Pa


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How Murdoch is solving one of sustainable energy's greatest challenges: Unreliability
Murdoch University researchers have come up with a potential solution for the central obstacle facing sustainable energy. Wind turbines don't turn on a still day. Solar doesn't work at night and can be hampered by cloud, dust or snow coverage. To make sustainable resources a reliable form of energy their excess needs to be stored in batteries, currently making them an expensive and impractical option.
Dr Manickam Minakshi has developed a water-based sodium-ion battery that has shown excellent potential for affordable, low-temperature energy storage.
The battery has the added advantage of being based on globally abundant and affordable sodium (iron, nickel and manganese), a leap forward for green energy.


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American scientists are developing a nasal spray that protects the body against the norovirus bug.
Scientists from Baylor College of Medicine in Texas found that successful trials of the device almost halved the risk of the winter vomiting bug.
The vaccine is inhaled as a dry powder spray and contains tiny amounts of the virus to help the body trigger immunity without displaying the symptoms.
The highly contagious norovirus bug spreads around the body quickly and causes nausea, excessive vomiting, diarrhoea and a high fever. Scientists hope that their nasal spray will rapidly reduce the number of norovirus victims, which claims between 600,000 to one million Brits a year.
"This is the first demonstration of protection in humans against what is a widespread and often serious illness," says Robert Atmar from the study.
"The number of hospitalisations and the healthcare costs associated with norovirus are staggering; a successful vaccine against norovirus would offer significant protection to patients as well as potential cost reductions for the healthcare system."
Last year, record numbers of norovirus were reported due to the coldest winter in 30 years and this year isn't faring any better with 14 hospital wards being closed due to outbreak last week in the UK.
Recently it was discovered that three quarters of British oysters contain the norovirus.
Protect yourself from more winter bugs with our round-up of the best natural remedies to fight colds and flu.
Garlic is well known for its immune system benefits and is best eaten raw or crushed in soups and hot drinks. Garlic combats snotty noses by releasing a compound called allicin, which is full of anti-bacterial and anti-fungal properties.
If you're struggling to get a good night's sleep, tackle the problem with a stick of celery. Celery contains phthalidesm which has sedative powers and helps the body shut off and rest easy during the night.
A great natural remedy for respiratory disorders as it helps to release mucus from the body. It is also an antispasmodic which helps relax bronchial tubes, clearing the airways. Brew a cup of thyme tea or use it as an oil to treat chesty coughs or emphysema.
Nosebleeds can be a symptom of cold and flu. Prevent this from happening by adding leafy greens to your diet. Packed with Vitamin K, greens fortify sensitive capillaries and help your blood clot quickly if you have a nose bleed.
Jujube tea is rich in Vitamin C and great for the immune system and is widely used for relieving aching throat muscles.
Carrots are ideal for treating cold-induced headaches as they contain beta-carotene, which can reduce inflammation in the blood vessels of the brain. Chop them up and put in a stew, grate them on top of a salad or blend them to create a headache-friendly soup.
We already know that proteins are best for boosting mid-afternoon energy slumps, and they work just as well with energy-zapping colds and flu. A handful of raw nuts helps give the body a well needed energy boost, especially almonds and walnuts.
When the flu bug strikes, chances are the lack of sleep, appetite and constant nose blowing will begin to wear you down. Lavender is great for calming the nerves and relieving feelings of anxiety and stress. Use either dried lavender to scent the room or apply lavender oil on your pulse points for an instant calming boost.
A low immune system can lead to weakened digestive system. Strengthen it by using pineapple which helps reduce intestinal inflammation and speeds the breakdown of protein, reducing gas and discomfort.


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Thanks for welcoming Scott Barnes to PEOPLE StyleWatch! The celebrity makeup artist has been hard at work lately, releasing his second book, Face to Face, and blogging for People.com. This week, he tells us how to translate red carpet looks into our own lives.
I know there was a lot of talk last week about Emmy Award beauty: who looked good and who — I don't know — maybe took last week's call to experimentation just… Continue reading Scott Barnes's Blog: How to Emulate Emmys Beauty Looks at Home


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OEM Parts
Break or wear a part out on your last ATV adventure? No problem. GearHead.com has 1.5 million factory fresh OEM parts to choose from for your favorite utility ATV manufacturers such as Arctic Cat, Can-Am, Honda, Kawasaki, Kymco, Polaris, Suzuki, and Yamaha. When you need to replace a part, make sure you go with genuine factory parts so you know you're getting the same part that came on your machine when it was born from the factory. Gearhead.com is the most legit online retailer for OEM ATV parts. With quality OEM parts from the factory, you can ride the trails in confidence knowing we have everything your utility ATV needs.
So whether you're conquering the rockies, hauling out a deer, or working on the farm, the ATV parts you buy from Gearhead.com are made to work. We offer a variety of parts from all major manufacturers to make it convenient and easy. Plus with our ultra-cool looking diagrams you no longer have to take your machine apart in your mind to figure out exactly which part you need, or the part the mind reader guy at the dealer counter thinks you need.


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Steve Bullard - January 22, 2013
Steven Dale Bullard was born Oct. 14, 1955 in Wray to Ronald and Margaret Bullard. He died Jan. 22, 2013 in Lakewood, surrounded by his family.
Steve graduated from Fort Collins High School in 1974. He attended CU, CSU and Cedar City, Utah for a period of time. He married Janel Campbell May 1, 1982. To this union, two children were born: Shawn Steven and Lindsey Cay. He founded, owned and operated Bullard Concepts.
Steve was preceded in death by his wife, Janel; father, Ron; grandfather, Burl Lockwood; grandparents, Elmer and Lamedia Bullard; and several aunts and uncles.
He is survived by his son, Shawn of Castle Rock; daughter, Lindsey and husband Clay Cushman of Arvada; fiancee, Mary Senter of Lakewood; mother, Margaret and husband James Scholl of Holyoke; sister, Sherri and husband Brad Brackhan of Holyoke; grandmother, Veva Lockwood of Holyoke; niece, Nicole and husband Jared Moore; nephew, Ryan Brackhan; and a host of relatives and friends.
Funeral services were held at Aspen Mortuary in Lakewood on Jan. 28.


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Rocket Engine, Liquid Fuel, XLR35-RM-1
This is the XLR35-RM-1, the liquid fuel rocket engine that powered the MX-774 test missile, a predecessor of the Atlas intercontinental ballistic missile. The engine produced 8,000 pounds of thrust from four chambers and was also gimballed. This meant it could be steered by the swivelling of each of the four chambers. The propellants were liquid oxygen and alcohol.
Three successful flights of the MX-774 were made at White Sands Proving Grounds, New Mexico, in 1948. No further flights were made, but the engine demonstrated the effectiveness of gimballing and also proved the missile's monocoque airframe, both features later incorporated into the Atlas. This object was donated to the Smithsonian by the Reaction Motors Division of the Thiokol Chemical Corporation in 1985.
Reaction Motors Division, Thiokol Chemical Corp.
- Country of Origin
- United States of America
- Manufacturer
- Reaction Motors, Inc.
- Type
- PROPULSION-Components (Engine Parts)
- Materials
- Aluminum, Steel, Plastic, Paint, Brass
- Dimensions
- Overall: 1ft 11 1/2in. x 2ft 2 1/4in., 280lb. (59.69 x 66.68cm, 127kg)
- Storage: 138.4 × 82.6 × 112.4cm, 186.9kg (54 1/2 × 32 1/2 × 44 1/4 in., 412lb.)


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Helmet maker Kali Protectives takes unwavering stance on safety
- By Logan VonBokel
- Published Feb. 4, 2014
- Kali Protectives got its start in motorcycle helmets. Owner Brad Waldron's goal is to bring similar safety standards to bicycle helmets, like the Sastra, a budget-minded and DOT-certified mountain bike helmet. Photo: Logan VonBokel | VeloNews.com
- The Sastra takes much of the technology from the ultra-lightweight Avatar 2 Carbon, but wraps it into an ABS rather than a carbon fiber shell. Photo: Logan VonBokel | VeloNews.com
- The Sastra uses the Composite Fusion Plus technology, using Cone-head foam technology. Photo: Logan VonBokel | VeloNews.com
- The $160 Kali Phenom road helmet uses much of the same technology as the Sastra, including the Composite Fusion Plus technology. Photo: Logan VonBokel | VeloNews.com
- The Cone-head technology spreads the forces from an impact into the cones. The cones dampen the blow by crushing and dispersing the forces through the low density foam sitting closer to the head. Photo: Logan VonBokel | VeloNews.com
- The Phenom also uses reinforced Super Vents, like the white vents on this model. Photo: Logan VonBokel | VeloNews.com
- The rear Super Vent of the Phenom is designed to disperse the forces of a blow across its reinforced body. The alternative is vents that crumple due to lack of reinforcement. Photo: Logan VonBokel | VeloNews.com
- The pyramids in the Cone-head technology are shown in the darker gray foam. The ligher gray foam is the lower density material. Photo: Logan VonBokel | VeloNews.com
- The black piece of foam is the super soft bumper fit foam. Both the Phenom and Loka use this foam. Photo: Logan VonBokel | VeloNews.com
- A cutaway from half of a Loka shows off the Composite Fusion Plus technology and the Cone-head pyramids. Photo: Logan VonBokel | VeloNews.com
PALOS VERDES, Calif. (VN) — "Would you rather get hit in the head with a pillow or a hammer?"
Kali Protectives' Bryan Mason asked that rather daft question last week to prove a highly salient point: though most would quickly pick the pillow, Mason believes that many accidentally pick the hammer during a helmet purchase.
It's not totally our fault; the marketing machines of helmet manufacturers don't use protection bywords like "low-density foam," "low-speed impact," or for that matter, "safety." And the reason they don't is simple: talking about saving our brains when we crash isn't sexy; we don't want to hear about, and it doesn't sell helmets. We want low weights, cooling, and good looks.
But buying a helmet on these attributes is like picking a restaurant because you like the cutlery. Everyone loves a nice fork, but it shouldn't be the deciding factor.
Kali Protectives owner and principle founder Brad Waldron is in the business of selling helmets, but he's an engineer by trade and a father at heart. A father of children who play impact sports, cycling included, Waldron, formerly of Specialized Bicycles, is trying to design helmets that do what they're intended to do — protect our brains from going splat inside of our skulls when we take a digger. It's obvious when chatting with Waldron about his work that he wants to build a better and safer helmet.
It's not an easy task, as most of the market is concerned with aerodynamics, ventilation, and weight. For 2014, the brand is bringing two new road helmets to market, as well as a budget-minded DOT-certified full-face model, the $150 Sastra.
The Phenom and Loka
Kali's latest helmets are the Phenom and Loka, priced at $160 and $100, respectively. They join the top-of-the-line Maraka in Kali's road line up. The pair of helmets will be available in the coming weeks and share several attributes, including Kali's Composite Fusion Plus technology.
The Phenom and Loka use another technology unique to Kali, called Bumper Fit. A very low density — very soft — foam is used in parts of the helmet that are important for a snug and comfortable fit. Where the Loka falls short of the Phenom is its lack of what Kali refers to as "Super Vents." Kali uses reinforced vents on the Phenom as well as on its flagship Maraka that use a thicker material than the rest of the polycarbonate shell. The Super Vents are designed to spread load across their surface so that safety is not compromised by the removal of foam necessary for venting.
The Composite Fusion Plus technology incorporates EPS foam that is fused to the outer shell of the helmet. This reduces the total force transferred to the head during an impact. With glued or taped shells, the head can suffer an additional impact of the foam moving against the shell. The Cone-head technology was invented by Australian physicist Don Morgan. Companies like Scott, Cannondale, and POC are also using the Cone-head technology on select helmets. Scott is even using the Cone-Head technology in its flagship road helmet, the Vanish.
Fused EPS foam is becoming more common among modern helmets, but few are also using high-density Cone-head technology, which features pyramids that sit closest to the shell and collapse upon impact, spreading the impact into a greater area of the low-density foam, which sits closest to the skull.
This is where Kali also differs, as Kali only uses foams that are 80 grams per cubic liter or lower. Other road helmets are using foams that are 120 grams per cubic liter — in other words, significantly more dense. Children's helmets, often considered the safest helmets on the market, use foams that are 25g per cubic liter.
Balancing tradeoffs
There is a trend, led by brands like Kali, toward helmets that make safety a priority over sexier attributes. The question is simple on its face: do you need the lightest, coolest, prettiest helmet on the market, or the safest one?
The answer, of course, comes down to what you value.
I've suffered several concussions, many attributed to years of ice hockey and failing to wear a mouth guard regularly. Yet, most recently I crashed in a short-track event and suffered a concussion. I was not going very fast, but the impact of my head bouncing off of a root was enough to rattle my brain. My helmet showed no damage.
The crash left me wondering. If I'd been wearing a different helmet, maybe one with more low-density foam, albeit likely not as well ventilated or as light, would I have been OK? I have no idea. Unfortunately there's no good way to accurately test helmet safety, though this is something that Waldron thinks about frequently. He's trying to remedy this shortcoming through testing that surpasses the CPSC standard, which most helmet aficionados will tell you does not do much to test anything beyond whether the helmet is intact after a high-speed fall.
Helmet design, at least for now, is largely a reflection of values — safety versus performance. No helmet currently available excels in all areas. But companies like Kali are working toward that goal, trying to build high-performance lids that will also dramatically improve head safety. At the very least, the debate is one worth having, and increasing options are never a bad thing.
Logan VonBokel spoke with Kali Protectives at Winter Press Camp in Palo Verdes. Winter Press Camp provided travel and lodging for the media event.
FILED UNDER: Bikes and Tech TAGS: helmets / Kali Protectives


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WebGL / Flash CopperCube 3D Game Tutorial and Sample Game Source Kit
Skill Level: Beginner / Views: 150 / System Requirements: Windows or Apple
New: FREE 3D Figures Content & Game Development TUTORIAL Make HTML5 WebGL GAME SOURCEFarmPeeps.com just published a FREE Tutorial and all the 3D resources needed to make a WebGL game using figures made from Poser in hours! Make your own 3D game to day at http://FarmPeeps.comFarmPeeps.com is a hobby website maintained by a 3D enthusiast like you. Its not perfect, but its fun! Come by and stock up on Farm Theme 3D Media
Getting started with Reality 2
Skill Level: Beginner / Views: 2130
This video shows how easy is to get started with Reality 2. With a set of intuitive materials and a User Interface that is designed for the artist, Reality brings to the Studio artist a workflow that is more natural and friendly than the one built-in inside Studio
Motion Estimation / Prtediction with PD Pro 7
Skill Level: Intermediate / Views: 80 / System Requirements: Windows Vista or 7, XP ok too., .Net framework 4
Here's another look at using Motion Estimation with the Motion Prediction Module from PD Pro 7, as applicable to videos and to rendered animations of 3D logos in this case. This shows a comparison of a traditional frame blending approach vs. the motion prediction approach.It may take a few tries to tweak the parameters, and get a good combination, but in the end it could be worth the effort, especially if the rendering of the frames took a long time and you can't re-render them with the added frames, economically speaking.Generally speaking, you'll want to consider this option if you have a short animation that needs to last longer, and thus you want to time-stretch it without going through re-rendering the whole lot in the 3D side, i.e. when it took hours to render and you can't afford to take even longer to render, say, 10x that many frames for a 10x timelapse.In this example, the 3D logo was rendered at high (but not highest) settings, took a minute or two per frame to render. This is not a typical case. You'll be more interested in this technique when it takes an hour per frame to render :-)The last clip was done with 60 frames per second and with global illumination enabled, adding significant rendering time to it all. In cases like these it will definitely be a time saver to use motion prediction. Even if it takes a few minutes to get the parameters right, in the end it's much shorter than rendering it in 3D over 300+ frames if you can get away with rendering just 30-60 frames and fill in the missing frames through motion estimated interpolation.staigermanus on 9:01AM Thu, 26 April 2012
Make Poser dynamic dress using Blender
Skill Level: Intermediate / Views: 917 / System Requirements: Poser and Blender (recent versions)
This tutorial shows how to get a model from Poser into Blender. Create a simple dress in Blender and get it back into Poser as a dynamic dress. (My first tutorial. Lemme knowwhat I might have forgotten)SailorJPS on 10:26AM Sun, 15 April 2012
Poser Install for Renderosity Zip
Skill Level: Beginner / Views: 2538 / System Requirements: Poser
This tutorial is to help buyers learn how to install (extract) the Renderosity Marketplace Zip files into the proper Poser folders after downloaing.
How to Make Your Own 8-bit Art
Skill Level: Beginner / Views: 128 / System Requirements: MS Paint
The 8-bit style of art, inspired by video games of the past, has taken on new life for the internet. Whether it's a web-based game, a tutorial or desktop icons, the range of uses for these little sprites is surprisingly large, and they're very easy to create. Inside I describe my process, what you can use to get started, and show some examples for reference.
GenX Plug-in Tutorial
Skill Level: Beginner / Views: 693 / System Requirements: GenX Plug-in for DAZ Studio 4
Today I made a quick video to show you how easy it is to transfer generation 4 characters to Genesis using the GenX plug-in. Enjoy.
Postwork~ Painting Realistic Looking Tears in Photoshop Elements 7
Skill Level: Beginner / Views: 572 / System Requirements: Photoshop Elements 7
Hi there, welcome! Being a big fan of postwork, I decided to upload this tutorial I created on my quick technique for painting realistic looking tears using Photoshop Elements 7.
DAZ Studio 4 Pose Bug Workaround
Skill Level: Beginner / Views: 302
If you use a PZ2 (Poser format) file on Genesis that breaks the joint rotation limits, DAZ Studio will ask you if you want to do so (unless you changed this feature in your preferences). BUT, if you use a DAZ Studio format such as .DSA or .DSF, it WILL NOT ASK, and then you might think the pose is broken because you have an arm sticking out of a head or something.This tutorial provides a simple solution until this bug gets fixed. I submitted the bug to DAZ and it has been verified.
Make a lavalamp with subsurface scattering shader
Skill Level: Beginner / Views: 234 / System Requirements: CINEMA 4D Release 13
This Tutorial is in German but you can also work with the Pictures.
Creating a Super-conforming clothing item
Skill Level: Beginner / Views: 841 / System Requirements: any modeling software, Morcloth
As a clothing creator, I cant count the number of times Ive created a piece of clothing only to find it doesnt fit anything but the original geometries of V4 or any model I useThen I learned about Morcloth This program helps to place the proper morph channels in your original clothingIm sure there are many ways to accomplish this and I by no means believe mine is the best, its just what works for meIf it helps one person, then this tutorial has accomplished what it was designed to do
Discover Bryce's hidden objects and resources
Skill Level: Beginner / Views: 361
Bryce has a few hidden objects and resources that are not easy to find if you are starting out and haven't yet explored the folders that have been installed. These short tutorials show you where to find them and how to use them, and in the process will also take you through using some of the Bryce labs.
Escape Studios
Skill Level: Beginner / Views: 1766
Renderosity exclusive video tutorial provided by Escape Studios.
Create Displacement Maps and 3D Spotlights w/ Photos
Skill Level: Intermediate / Views: 202 / System Requirements: Adobe Photoshop CS3 - CS5.5
This is a tutorial to demonstrate how this poster was created , using displacement maps and adding 3D spotlights.
Create Bling Text Using Textures
Skill Level: Intermediate / Views: 145 / System Requirements: Adobe Photoshop CS3 - CS5.5
Using a diamond stud texture to create a Bling text style
Skill Level: Intermediate / Views: 183 / System Requirements: Adobe Photoshop CS3 - CS5.5
In this tutorial we're going to be converting a photo into a text image.
How to create a semi-transparent text effect style
Skill Level: Beginner / Views: 159 / System Requirements: Adobe Photoshop CS3 - CS5.5
creating a semi-transparent text effect style
Rendering Tips and Tricks: Getting the Most Out of Your Poser 3D Renders- Webinar
Skill Level: Regular / Views: 685 / System Requirements: Poser
Join Stefan Werner, Senior Software Engineer for Poser in this 1-hour session as he shows you informative ways to enhance your Poser 3D renders. He will demonstrate how to leverage the new and improved rendering features, including Subsurface Scattering, available in Poser 9 and Poser Pro 2012. Stefan will also discuss how to optimize your render settings to master features such as depth of field, indirect light, and ambient occlusion. Learn why more isn't necessarily better when it comes to rendering and find the perfect balance between quality and performance.
How to Create Characters with Character in Poser - Webinar
Skill Level: Regular / Views: 679 / System Requirements: Poser
In this 1-hour session you will learn how to truly get the most out of your Poser runtime. You will learn how to create a literal cast of thousands from the free assets that come with the program and with tools already provided with the program. Create your own characters with your own sense of style from realistic to cartoony. The tutorial will cover use of the morphing tool, the art of frankensteining (making two figures into one), parenting, and a little bit of Zbrush.
Beginner's Guide to Indoor Scenes with Reality/LuxRender in DAZ Studio
Skill Level: Beginner / Views: 497
Learn all you need to know to get started successfully using the Reality Plug-in for DAZ Studio to make simple indoor scenes.
How to customize the Bryce interface
Skill Level: Beginner / Views: 192 / System Requirements: Bryce 6/7
Something that may not be obvious when you first start using Bryce is that it has some simple customization features. The tutorial covers:1.Customizing the interface by moving the palettes,2. Changing the background colour/texture of the scene space,3.Changing the object display modes.So if you don't know how to do any of these yet this tutorial is for you!
Poser Dynamic Clothing Tutorial: How to Create and Save a Dynamic Gown
Skill Level: Intermediate / Views: 699 / System Requirements: Poser
This tutorial shows the steps I take once I created a mesh of a piece of clothing in a separate 3D modelling application and imported it into Poser.
Poser Dynamic Clothing Tutorial: Create a Dynamic Shirt and Skirt Set with Belt Constraint
Skill Level: Intermediate / Views: 697 / System Requirements: Poser
This tutorial shows you how to run dynamic cloth simulations on two pieces of clothing each with different cloth settings. It shows you how to ensure that the shirt remained tucked-in within the belt during the simulation. You can preview the finished result at the end of the tutorial.
Utiliser les vetements dynamics
Skill Level: Beginner / Views: 215 / System Requirements: poser
Voici un tuto qui vous aidera comprendre comment utiliser les vetements dynamics, et notamment leur superposition.
How to use dynamics clothes
Skill Level: Beginner / Views: 514 / System Requirements: Poser
Here is a tutorial that will help you understand how to use clothes dynamics, including their superpositions.


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Nicolas Larmonier, PhD, is an Associate Professor of Pediatrics, with a joint appointment with Immunobiology at the University of Arizona College of Medicine. Dr. Larmonier's primary field of research has essentially focused on cancer immunology and immunotherapy, with a particular emphasis on the understanding of the mechanisms of tumor-induced immunosuppression.He has developed different research areas pertaining to the role and modalities of induction of regulatory lymphocytes (Treg) and Myeloid-Derived Suppressor Cells (MDSC), two populations of immunosuppressive cells which impair anti-cancer immune responses. He has also extensively studied the non-conventional cytotoxic activity of dendritic cells, the main "messengers" of the immune system. The role of newly described T helper lymphocyte subsets, such as Th-17, in cancer is being explored. Strategies to eliminate or inactivate tumor-induced immunoinhibitory Treg or MDSC are currently being evaluated. Combination approaches associating chemotherapeutic drugs and immunotherapy are also under investigation. He has published over 35 articles in the field.Dr. Larmonier has led the research work of post-doctoral fellows, graduate, undergraduate, medical and high school students and is faculty member in the Immunology and Cancer Biology graduate programs.
Dendritic Cell Tumor Killing Activity And Its Potential Applications In Cancer Immunotherapy. Source: Critical Reviews In Immunology
March 20th, 2013 PMID: 23510023 Nicolas Larmonier
Universally viewed as the sentinels and messengers of the immune system and traditionally referred to as professional antigen-presenting cells, dendritic cells (DCs) play a fundamental role in antitumor immunity. DCs are uniquely equipped with the ability to acquire, process, and present to T lymphocytes tumor-derived antigens. They can drive the differentiation of naive T cells into activated tumor-specific effector lymphocytes. DCs also dictate the type and regulate the strength and duration of T-cell responses. In addition, they contribute to natural killer and natural killer T-cell antitumoral function and to B-cell-mediated immunity. Besides this cardinal role as orchestrators of innate and adaptive immune responses, many studies have provided evidence that DCs can also function as direct cytotoxic effectors against tumors. This less conventional aspect of DC function has, however, raised controversy as it relates to the origin of these cells and the induction, regulation, and mechanisms underlying their tumoricidal activity. The possible impact of the cytotoxic function of DCs on their capability to present antigens also has been the focus of intensive research. This review examines these questions and discusses the biological significance of this nontraditional property and possible strategies to exploit the killing potential of DCs in cancer immunotherapy.

Th1 And Th17 Lymphocytes Expressing Cd161 Are Implicated In Giant Cell Arteritis And Polymyalgia Rheumatica Pathogenesis. Source: Arthritis And Rheumatism
October 31st, 2012 PMID: 22833233 Nicolas Larmonier
OBJECTIVE:
Giant cell arteritis (GCA) is the most frequently occurring vasculitis in elderly individuals, and its pathogenesis is not fully understood. The objective of this study was to decipher the role of the major CD4+ T cell subsets in GCA and its rheumatologic form, polymyalgia rheumatica (PMR).

METHODS:
A prospective study of the phenotype and the function of major CD4+ T cell subsets (Th1, Th17, and Treg cells) was performed in 34 untreated patients with GCA or PMR, in comparison with 31 healthy control subjects and with the 27 treated patients who remained after the 7 others withdrew.

RESULTS:
Compared with control subjects, patients with GCA and patients with PMR had a decreased frequency of Treg cells and Th1 cells, whereas the percentage of Th17 cells was significantly increased. Furthermore, an analysis of temporal artery biopsy specimens obtained from patients affected by GCA for whom biopsy results were positive demonstrated massive infiltration by Th17 and Th1 lymphocytes without any Treg cells. After glucocorticoid treatment, the percentages of circulating Th1 and Th17 cells decreased, whereas no change in the Treg cell frequency was observed. The frequency of CD161+CD4+ T cells, which are considered to be Th17 cell precursors, was similar in patients and control subjects. However, these cells highly infiltrated GCA temporal artery biopsy specimens, and their ability to produce interleukin-17 in vitro was significantly enhanced in patients with GCA and patients with PMR and was correlated with a decrease in the phosphorylated form of STAT-1.

CONCLUSION:
This study is the first to demonstrate that the frequency of Treg cells is decreased in patients with GCA and patients with PMR, and that CD161+CD4+ T lymphocytes, differentiated into Th1 cells and Th17 cells, are involved in the pathogenesis of GCA and PMR.

Cytotoxic Dendritic Cells Generated From Cancer Patients. Source: Journal Of Immunology (Baltimore, Md. : 1950)
July 29th, 2011 PMID: 21804019 Nicolas Larmonier
Known for years as professional APCs, dendritic cells (DCs) are also endowed with tumoricidal activity. This dual role of DC as killers and messengers may have important implications for tumor immunotherapy. However, the tumoricidal activity of DCs has mainly been investigated in animal models. Cancer cells inhibit antitumor immune responses using numerous mechanisms, including the induction of immunosuppressive/ tolerogenic DCs that have lost their ability to present Ags in an immunogenic manner. In this study, we evaluated the possibility of generating tumor killer DCs from patients with advanced-stage cancers. We demonstrate that human monocyte-derived DCs are endowed with significant cytotoxic activity against tumor cells following activation with LPS. The mechanism of DC-mediated tumor cell killing primarily involves peroxynitrites. This observed cytotoxic activity is restricted to immature DCs. Additionally, after killing, these cytotoxic DCs are able to activate tumor Ag-specific T cells. These observations may open important new perspectives for the use of autologous cytotoxic DCs in cancer immunotherapy strategies.

Modulation Of Neutrophil Motility By Curcumin: Implications For Inflammatory Bowel Disease. Source: Inflammatory Bowel Diseases
January 12th, 2011 PMID: 20629184 Nicolas Larmonier
BACKGROUND:
Neutrophils (PMN) are the first cells recruited at the site of inflammation. They play a key role in the innate immune response by recognizing, ingesting, and eliminating pathogens and participate in the orientation of the adaptive immune responses. However, in inflammatory bowel disease (IBD) transepithelial neutrophil migration leads to an impaired epithelial barrier function, perpetuation of inflammation, and tissue destruction via oxidative and proteolytic damage. Curcumin (diferulolylmethane) displays a protective role in mouse models of IBD and in human ulcerative colitis, a phenomenon consistently accompanied by a reduced mucosal neutrophil infiltration.

METHODS:
We investigated the effect of curcumin on mouse and human neutrophil polarization and motility in vitro and in vivo.

RESULTS:
Curcumin attenuated lipopolysaccharide (LPS)-stimulated expression and secretion of macrophage inflammatory protein (MIP)-2, interleukin (IL)-1β, keratinocyte chemoattractant (KC), and MIP-1α in colonic epithelial cells (CECs) and in macrophages. Curcumin significantly inhibited PMN chemotaxis against MIP-2, KC, or against conditioned media from LPS-treated macrophages or CEC, a well as the IL-8-mediated chemotaxis of human neutrophils. At nontoxic concentrations, curcumin inhibited random neutrophil migration, suggesting a direct effect on neutrophil chemokinesis. Curcumin-mediated inhibition of PMN motility could be attributed to a downregulation of PI3K activity, AKT phosphorylation, and F-actin polymerization at the leading edge. The inhibitory effect of curcumin on neutrophil motility was further demonstrated in vivo in a model of aseptic peritonitis.

CONCLUSIONS:
Our results indicate that curcumin interferes with colonic inflammation partly through inhibition of the chemokine expression and through direct inhibition of neutrophil chemotaxis and chemokinesis.

Personalized Dendritic Cell Based Tumor Immunotherapy. Source: Immunotherapy
July 23rd, 2010 PMID: 20161666 Nicolas Larmonier
Advances in the understanding of the immunoregulatory functions of dendritic cells (DCs) in animal models and humans have led to their exploitation as anticancer vaccines. Although DC-based immunotherapy has proven clinically safe and efficient to induce tumor-specific immune responses, only a limited number of objective clinical responses have been reported in cancer patients. These relatively disappointing results have prompted the evaluation of multiple approaches to improve the efficacy of DC vaccines. The topic of this review focuses on personalized DC-based anticancer vaccines, which in theory have the potential to present to the host immune system the entire repertoire of antigens harbored by autologous tumor cells. We also discuss the implementation of these vaccines in cancer therapeutic strategies, their limitations and the future challenges for effective immunotherapy against cancer.

Killer Dendritic Cells And Their Potential For Cancer Immunotherapy. Source: Cancer Immunology, Immunotherapy : Cii
July 18th, 2009 PMID: 19618185 Nicolas Larmonier
Known for years as the principal messengers of the immune system, dendritic cells (DC) represent a heterogeneous population of antigen presenting cells critically located at the nexus between innate and adaptive immunity. DC play a central role in the initiation of tumor-specific immune responses as they are endowed with the unique ability to take up, process and present tumor antigens to naïve CD4(+) or CD8(+) effector T lymphocytes. By virtue of the cytokines they produce, DC also regulate the type, strength and duration of T cell immune responses. In addition, they can participate in anti-tumoral NK and NKT cell activation and in the orchestration of humoral immunity. More recent studies have documented that besides their primary role in the induction and regulation of adaptive anti-tumoral immune responses, DC are also endowed with the capacity to directly kill cancer cells. This dual role of DC as killers and messengers may have important implications for tumor immunotherapy. First, the direct killing of malignant cells by DC may foster the release and thereby the immediate availability of specific tumor antigens for presentation to cytotoxic or helper T lymphocytes. Second, DC may participate in the effector phase of the immune response, potentially augmenting the diversity of the killing mechanisms leading to tumor elimination. This review focuses on this non-conventional cytotoxic function of DC as it relates to the promotion of cancer immunity and discusses the potential application of killer DC (KDC) in tumor immunotherapy.

Imatinib Mesylate Inhibits Cd4+ Cd25+ Regulatory T Cell Activity And Enhances Active Immunotherapy Against Bcr Abl Tumors. Source: Journal Of Immunology (Baltimore, Md. : 1950)
November 4th, 2008 PMID: 18981115 Nicolas Larmonier
Imatinib mesylate (Gleevec, STI571), a selective inhibitor of a restricted number of tyrosine kinases, has been effectively used for the treatment of Philadelphia chromosome-positive leukemias and gastrointestinal stromal tumors. Imatinib may also directly influence immune cells. Suppressive as well as stimulating effects of this drug on CD4(+) and CD8(+) T lymphocytes or dendritic cells have been reported. In the current study, we have investigated the influence of imatinib mesylate on CD4(+)CD25(+)FoxP3(+) regulatory T cells (Treg), a critical population of lymphocytes that contributes to peripheral tolerance. Used at concentrations achieved clinically, imatinib impaired Treg immunosuppressive function and FoxP3 expression but not production of IL-10 and TGF-beta in vitro. Imatinib significantly reduced the activation of the transcription factors STAT3 and STAT5 in Treg. Analysis of Treg TCR-induced signaling cascade indicated that imatinib inhibited phosphorylation of ZAP70 and LAT. Substantiating these observations, imatinib treatment of mice decreased Treg frequency and impaired their immunosuppressive function in vivo. Furthermore, imatinib mesylate significantly enhanced antitumor immune responses to dendritic cell-based immunization against an imatinib-resistant BCR-ABL negative lymphoma. The clinical applications of imatinib mesylate might thus be expanded with its use as a potent immunomodulatory agent targeting Treg in cancer immunotherapy.


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It's no surprise that light rail and the Columbia River Crossing have largely dominated the talk surrounding C-Tran's Proposition 1. Both politically charged issues had a yearslong head start on the sales tax measure now tied to them this fall.
Often overshadowed in the debate is bus rapid transit, the lesser-known proposed beneficiary of Proposition 1.
"What I've noticed is that people are hardly aware of BRT at all," said Vancouver resident Harry Kiick, a frequent C-Tran rider.
Kiick and a small group of Vancouver residents are trying to change that. They're hoping to turn the conversation away from light rail and toward a BRT system they say would bring a welcome boost to Vancouver's Fourth Plain community. A few supporters on Wednesday handed out fliers and information at Clark College. They have a handful of events planned for this month.
One problem: Getting people to vote for BRT also means getting them to vote for light rail funding — a tough pill to swallow for CRC opponents, regardless of how they feel about BRT. Some CRC and light rail backers have said they're not on board with a sales tax hike to help pay for it, and thus oppose Proposition 1.
All of that leaves bus rapid transit advocates with an uphill climb to get support — and before that, get noticed.
"That's what we're going to need to do," Kiick said.
If approved, Proposition 1 would raise the local sales tax rate by 0.1 percentage point within the C-Tran service area. The resulting revenue — about $4.6 million annually at first — would cover the cost of operating light rail in Vancouver, and help build a bus rapid transit line on the city's Fourth Plain corridor.
Bus rapid transit uses larger vehicles, raised boarding platforms, specialized signals and other features in an effort to move passengers more quickly and efficiently. Vancouver's proposed system, stretching from downtown to the Westfield Vancouver mall, would cost an estimated $40 to $55 million. Project leaders have said about 70 percent of that could be covered by federal grants.
Critics have characterized BRT as an ill-advised initiative with too much cost and too little benefit. But the concept cleared the C-Tran board, Vancouver City Council and Southwest Washington Regional Transportation Council, all of which signaled their approval earlier this year.
Among the residents now supporting bus rapid transit is Derya Ruggles, who lives in Vancouver's newly formed Maplewood neighborhood. Bringing the system to the city's Fourth Plain corridor would improve the area and build community, Ruggles said. She feels bus rapid transit is worth pursuing with or without light rail, which is planned as part of the $3.5 billion CRC project.
"To me, it's a solution," Ruggles said of BRT. "It's going to revitalize the whole neighborhood."
Kiick agreed.
"The BRT is not just buses," Kiick said. "It's making Fourth Plain a better place to be once you get there."
On Wednesday, Clark College student Madison Syverson helped run the campus table promoting BRT at Gaiser Hall. She and Kiick set up next to a voter registration table, which may have been a benefit. Syverson, 19, said many of her peers simply aren't plugged into local politics like older voters are.
Should Proposition 1 fail, what happens next is unclear. C-Tran must come up with some kind of local funding before it can receive a federal grant for bus rapid transit. It will ultimately be up to the C-Tran board to decide how to proceed if voters say no to a sales tax hike, said C-Tran public affairs director Scott Patterson. If it decides to press forward without a sales tax increase, the agency may have to settle on another plan as soon as next year if it hopes to keep the BRT project on its current timeline.
Ruggles and Kiick said they see BRT and light rail as two separate issues, despite efforts to connect the two. Proposition 1 may decide the fate of both on Nov. 6.
Eric Florip: 360-735-4541; http://twitter.com/col_enviro; email@example.com.


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Archive - Sep 2013
September 23rd
Notre Dame's Grant may be one (more) and done
On Mon, 09/23/2013 - 8:46pm.
Chicago Tribune/Brian Hamilton
Related Players:
P.J. Hairston practicing with UNC
On Mon, 09/23/2013 - 7:22pm.
ESPN/Jeff Goodman
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Hand injury to keep Hoosiers freshman forward Troy Williams on sideline for a 'few' weeks
On Mon, 09/23/2013 - 3:17pm.
The Washington Post
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Creighton nabs 2014 forward Leon Gilmore
On Mon, 09/23/2013 - 3:14pm.
NBC Sports/Scott Phillips
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Eli Carter, Joseph Young highlight list of six transfers waiting on a waiver
On Mon, 09/23/2013 - 3:12pm.
NBC Sports/Rob Dauster
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Cliff Alexander cuts Kentucky, adds UConn, Oregon
On Mon, 09/23/2013 - 10:18am.
ESPN Chicago/Scott Powers
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By the numbers: Making the case for Spike Albrecht
On Mon, 09/23/2013 - 10:03am.
UM Hoops/Dylan Burkhardt
Related Players:
Report: UConn's Tyler Olander pleads guilty, but DUI charges dropped
On Mon, 09/23/2013 - 9:57am.
NBC Sports/Rob Dauster
Related Players:
Jack Williams, Trevor Stanback can be imposing duo
On Mon, 09/23/2013 - 8:18am.
Los Angeles Times/Eric Sondheimer
Related Players:
September 22nd
Nairn Hopes to Decide Soon
On Mon, 09/23/2013 - 6:42am.
Zags Blog/Adam Zagoria
Related Players:


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This past week, the Guardian ran an op-ed by Zoe Williams that warmed my cold Harpy heart.
Over-40 women, you've given birth to a healthy facet of modern life, reads the headline. Quite simply, there is no best age to be pregnant.
Hell. Yes. For once, a story about older mothers that isn't full of won't someone think of the children! hand-wringing or if you wait too long, you'll be infertile! scaremongering.
The number of children born to women over 40 in England and Wales hit a record 27,000 last year, and has trebled in the last 20 years – a trend that has alarmed medical experts. Philip Steer, a professor of obstetrics, said: "There are two big problems with [postponing children]. First, you are less and less likely to get pregnant. Second, the physical risks of pregnancy, such as pre-eclampsia, diabetes, kidney problems and tiredness, go up from the age of 30." Nobody would argue with any of that; but nor does a simple deduction follow that women over 40 should avoid getting pregnant.
I've written before about the rush to judge women who use fertility treatments to conceive postmenopausally. The condemnation of women who have children later in life—by whatever means—is simply another visit from the uteri police, along with an implicit condemnation of women who have the nerve to de-prioritize reproduction, if only temporarily.
Williams writes:
The judgmental tone is all rooted in a timeless anxiety that women are too feckless and/or stupid to be left in charge of growing children – an anxiety I have an ever growing awareness of, the more background misogyny I realise there still is. Propagation is the main work of any species, and if you seriously believe women to be inferior, it must be incredibly aggravating to see them in charge of it.
It's always aggravating to the Patriarchy when women want something other than all babies all the time, even though men often make the exact same choice to delay having children.
You can easily discredit any of the usual arguments condemning older mothers by pointing out that they apply equally, if not more so, to older fathers. Most of the anti-older-mother arguments are irrelevant, or part of a double standard, as Williams points out:
Furthermore, it's quite true – women are feckless and/or stupid, but only to the same degree as the rest of the population. Some women will have a baby at the last possible moment, just as some people will file a tax return the day before they get fined. Some women will get breast cancer as a result of late-age births, that's just a fact. Some men will get bowel cancer because they don't get enough exercise, and maybe 40 years ago they would have been working manually and got plenty.
But in a chauvinist world, older dads tend to get a slap on the back and a fond ribbing about how their guys can still swim, whereas older moms get the side-eye from their neighbors, the media and the medical establishment, (unless they're Sarah Palin, who's used her over-40 pregnancy to burnish her reputation as an anti-abortion crusader and Good Christian Wife).
But even if you play by the rules and have children young, there's still no guarantee you won't be smacked with a different double-standard:
The people who hector mothers in the 35-plus bracket would be (indeed, are) the same people who berate mothers living on benefits because they had children young and can't afford to go back to work.
Mega-bestselling author J.K. Rowling experienced exactly that backlash as a young single mother and attacked it in a recent op-ed:
Women like me (for it is a curious fact that lone male parents are generally portrayed as heroes, whereas women left holding the baby are vilified) were, according to popular myth, a prime cause of social breakdown.
If you have babies too young, you're a disgrace, and a burden on society. Have them too old, you're unnatural and a bad mother. It's the classic double bind. It's worth noting that J.K. Rowling got caught in both sides of the double bind, as she is also one of the "35 plus bracket" moms, having had two children after that age, with the younger born shortly before her 40th birthday.
The conclusion of Williams's essay is the best part:
Mothers over the age of 40 may have swelled in numbers…but they haven't done anything wrong. It's savagely annoying to see them presented as a social problem. All these reports should start with a simple word: "congratulations".
Hear, hear. If those over-40 moms represent "a social problem," what about their mates? A small percentage of those women may have conceived via artificial insemination, but the vast majority got pregnant the old-fashioned way: with middle-aged men who are somehow magically exempt from being labelled a social problem, even as they do exactly the same thing as the women.
The take-home lesson here? Have children whenever you're ready. You'll get blowback regardless of your choice, so you might as well prioritize your own health, finances and well-being, because the one thing that's certain is society won't do it for you.


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BLUE RUIN: Jeremy Saulnier's Brilliant Revenge Thriller Gets Equally Brilliant New UK Trailer
Full marks to the marketing team at the UK's Picturehouse Entertainment. They've got one hell of a film on their hands with Jeremy Saulnier's Blue Ruin, they clearly know it, and they've just gone and released what may very well be an absolutely perfect trailer for the film. Haunting and evocative, troubling and mysterious, this tells you just the care bones of the concept while draping you in the tone of the film itself and now it's got me all worked up and wanting to watch the full picture again.
Watch the new trailer below. And then watch it a second time.
A mysterious outsider's quiet life is turned upside down when he returns to his childhood home to carry out an act of vengeance. Proving himself an amateur assassin, he winds up in a brutal fight to protect his estranged family.
Watch the new trailer below. And then watch it a second time.
Around the Internet:


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Ready in 1 hour 45 minutes
My maternal grandmother made an incredible southern pineapple upside-down cake. The cake was less sweet than the traditional old fashioned version and the recipe included stone-ground cornmeal which gave the cake an unusual and unique texture (closer to a sweet corbread or sweet polenta than to a traditional cake). Her cake was one of my father's favorite desserts (he was never a big fan of sweets) and my mother would make it for him often. Once both my mother and grandmother had pass away, the recipe was lost. We could not find a written copy of it anywhere. This recipe is adapted from a recipe belonging to my favorite Food Network culinary personality, Alton Brown. Alton's cake is the closest I've found to my grandmother's recipe. I believe the only differences being that my grandmother added a little of the canned pineapple juice to the cake batter and she sometimes (but not always) added some dark rum or brandy to both the pineapple glaze as well as the cake batter. She would also occasionally lightly drizzle the finished cake with some additional dark rum or brandy. This homey cake is very simple to make, is very tasty with lots of wonderful flavor, and has a very interesting crunchy texture which I enjoy immensely.
17 people want to try | 40 have favorited
Adjust oven rack to lower-middle position and heat oven to 350 degrees F.
In a microwave-safe bowl (or in a suacepan or medium-low heat), bring the milk to a boil. Remove the milk from the microwave (or turn off heat under saucepan). Slowly stir in the cornmeal with a whisk to avoid lumps. Set aside and let soak at room temperature for 30 minutes.
Spread the pecans on a baking sheet and toast in the 350 degree F oven, shaking the pan occasionally, until lightly golden, about 15 to 20 minutes. Set aside to cool.
For the topping: Using an ovenproof 10-inch heavy skillet (preferably well-seasoned cast-iron) over medium heat, melt butter until foam subsides. Add the brown sugar to the melted butter and stir until the sugar dissolves, about 5 minutes. Remove the skillet from the heat and carefully place 1 slice of pineapple in the center of the pan. Arrange the other 5-6 slices (depending on their size) around the center slice in a circle. Place the cherries in the centers of the pineapple slices and sprinkle the toasted nuts evenly over the fruit. Drizzle pineapple juice over top.
For the cake: Sift the flour, baking powder, and salt into a medium mixing bowl, whisking to combine. In a separate mixing bowl, whisk the eggs. Add the sugar to the eggs, whisking to combine. Add the canola oil and whisk to combine. Add the cornmeal and milk mixture to the egg mixture, whisking to combine. Add this to the flour mixture and stir just until combined. Pour the batter over the fruit in the skillet. Using a spatula, spread the batter evenly over the fruit, building up the outside edges and leaving a shallower center so the cake will be level when baked. Place skillet on the lower-middle rack of the 350 degree oven and bake until cake is golden brown and toothpick inserted into center of cake comes out clean, about 40 to 45 minutes. Remove from oven and let cool for 30 minutes in the skillet. Place an inverted serving platter over the skillet. Carefully invert skillet and platter together. Repositioning the fruit if necessary. Cut into pieces and serve as is, with sweetened whipped cream, or top each piece of warm cake with vanilla ice cream. Good hot, warm or at room temperature.
Makes one 10-inch cake, or 6 to 8 servings.
If the cake texture is too gritty or dense for your taste, a mediun or (if you must) even a fine grind cornmeal can be substituted for the coarse ground cornmeal. The finer the grind of the cornmeal you use, the more tender the resulting cake will be...but you'll also lose the the crunchy texture that makes this cake so unique.
|My private notes
Porpo83 4y agoDelicious! I did sneak a bit of vanilla into the batter and used medium grind cornmeal. Very sweet treat. Next time I'll cut the sugar in the batter a bit. Thank-you sgrishka.
slsmarks 5y agoMy husband thinks this is the best Pineapple Upside-down cake I've ever made. I also have used mandarins, pears, peaches. We like the crunch of the cornmeal.
sgrishka 8y agoIf the cake texture is too gritty or dense for your taste, a mediun or (if you must) even a fine grind cornmeal can be substituted for the coarse ground cornmeal. The finer the grind of the cornmeal you use, the more tender the resulting cake will be...but you'll also lose the the crunchy texture that makes this cake so unique. [I posted this recipe.]


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MAR 27, 2013 - ABC News/ESPN
A Must Read - Share
Pitcher J.A. Happ and the Toronto Blue Jays have agreed to a $9.1 million, two-year contract that adds an additional $5.4 million and one season to the deal he reached in January.
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Join the 8th Annual City Manager's Step Up to Wellness 5K Run/Walk
Whether you walk, jog, or run, grab your family and friends and join City of San Antonio employees and the entire...
Public Invited to Attend Charter Review Commission Meetings
The public is encouraged to attend upcoming meetings of the City of San Antonio's Charter Review Commission...
Pre-K 4 SA Accepting Applications for 2015-2016 School Year
Pre-K 4 SA is already preparing for the upcoming 2015-2016 academic year...
Distracted Driving Ordinance Takes Effect in San Antonio
On Jan. 1, 2015, the City's Distracted Driving Ordinance, passed by San Antonio City Council on Nov. 6, 2014...
Deadline for 2015 MLK, Jr. Commission Scholarship Applications is February...
The 2015 Martin Luther King, Jr., Scholarship application is currently available.
Applications for a place on the May election ballot will be accepted until...
Applications can currently be filed for a place on the May 9 City Council General Election ballot.
DCCD Currently Accepting 2015 National Poetry Month Event Submissions
April is National Poetry Month and the City of San Antonio invites all agencies, organizations, groups, and/or...
San Antonio Public Library Celebrates Black History Month
February is Black History Month and the San Antonio Public Library will celebrate with a variety of events and...
SAPL Hosts Mayor's Book Club
The San Antonio Public Library has launched its Spring Mayor's Book Club.
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Tax season has arrived, and the Volunteer Income Tax Assistance (VITA) Program is ready to help.
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text:
You, you, you can look up, I never come down
Home boy, I tap dance on the clouds
Who, who, who is it?
You, you, you can look up, I never come down
Home boy, I tap dance on the clouds
Who, who, who is it?
You, you, you can look up, I never come down
Home boy, I tap dance on the clouds
Who, who, who is it?
You, you, you can look up, I never come down
I tap dance on the clouds
[Verse 1]
Yeah, I keep it plainer than Pat, dog
So plain it's almost like I don't even rap, yo
Mack load, with flame from a spawning of hauntings that aren't me
Even with my damn eyes open
Yeah, it's like my own never never land
Smokin' on kush, from a bush you'll never touch
Being approached by hoes before you couldn't fuck
And all they wanna know if you be down (you be down)
If you really understand what happen from point A
What, hey, how you doing it wasn't even enough
To escape but I can't go
See I dream on and I'm over the peons
While I be doin' the beyond the
Hatin' niggas be puzzled like how did he get on?
See, I did not dare perform with that coolery
So ante like nothing else matters
Walkin' with a spirit so tattered
[Verse 2]
New type of warrior
Modern day hippie if I get enough sticky
And if you don't get it I'll explain it to you simply
And iffy iffy, then homie probably never get me
Nothin' really special about lil' ol' Cudder
Except the fact I'd slit my own throat for my mother
If it could make it stress free and then my brother could sacrifice
A meal best served raw with a little steak sauce
Oh no, I bet you probably think I'm looney tune
After big big country bought an album from a leak through
He was cool but just seems some type whatchamacall
Other worldly, but I'm more of a worldly other
Sucker niggas like to state they undercover
But I'll peep ya, I'll see you from my cloud sanctuary
And there's something about Mary
She made me un-tame
There was issues way before I smoked the phillies
[Verse 3]
Expedited for you so homie run to it
We makin' the damn dough, who knew it
And everybody in the game with the same ol'
No-no's I'll be doin' it, but Cudi from a different mode
You can keep it goin' though, no I will never slow
Ol' girl want purp, she is silly, yo
I ain't trippin', I'm skippin' while I'm sippin' in
While I go in though (again and again)
Tell them motherfuckin' let somebody tell new ones
If you get high still strive to be someone
I am not a role model but I am the blueprint
Superstar concerts and honors when I spit
Only can be me, Scott, no one can do it, K
Only, I don't mean to be, I do it the CuDi way
No need to be mad if you not me
Lookin' for ill shit, you know where to find KC
Yeah, you know where to find KC
"Never Come Down" is part of Kid Cudi's second mixtape "Cudderisback".


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bit of a bent parallel there wosi , this time last year stoner had a broken foot , and it just so seems vales team mate has a broken collarbone , but i won't rain on your parade son , lets just pretend your on to something.


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MAY 27, 2014 - Cleveland Plain Dealer
A Must Read - Share
The Cavaliers are beginning to interview coaching candidates.
CLEVELAND, Ohio -- Chicago Bulls assistant coach Adrian Griffin will interview with the Cavaliers today for their head coaching vacancy. He is believed to be the first coach to actually interview for the position.
Los Angeles Clippers assistant Tyronn Lue will interview later this week, followed by former Memphis coach Lionel Hollins. The Cavs also asked permission to speak to Clippers associate head coach Alvin Gentry, but it's unclear if an interview with him has been scheduled.
After weeks of
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I <3 SANTA shirt, Bow and leggins set
I love santa
The holidays are here. What a perfect Christmas set for your Lil Diva!
Please allow 1- 2 weeks to create your product. Pick up date will be Dec. 3rd on this set.
6 mos -2t is made on a onesie, shirt or long sleeve. ( please specify at checkout)
3T-7/8 will be made on a short sleeve.
You may add a tutu bottom to any of these sets.