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Masafumi Kurosumi
Released: November 07, 2007
Masafumi Kurosumi, Hiroyuki Takei
Sentinel lymph node (SLN) biopsy has become a common procedure for breast cancer patients. Many reported feasibility studies have revealed a high identification (95.4% of 2,125 cases) and accuracy rate on histopathological analysis (94% frozen and 97% paraffin). However, about 5 to 8% of cases false-negative are in this examination. Various methods of histopathological examination have been reported by many authors, but the Philadelphia consensus meeting recommended that sections less than 2.0 mm in thickness should be prepared and examined to detect metastasis larger than 2.0 mm. In addition, immunohistochemistry for cytokeratin is considered to be useful to detect isolated tumor cells (ITC) in the representative sections. On the other hand, real-time reverse transcriptase-polymerase chain reaction (RT-PCR) might detect micrometastasis (larger than 0.2 mm) (sensitivity and specificity; 89.5% and 96.7% frozen sections) and expected to be used as a routine method instead of histopathological examination.
Kazuyoshi Motomura, Sachiko Nagumo, Yoshifumi Komoike, Hiroki Koyama, Hideo Inaji
Accurate intraoperative diagnosis of sentinel node metastases enables the selection of patients for axillary lymph node dissection, thus avoiding an unnecessary additional operation in patients with false-negative results. The main reason for false-negative results of imprint cytology was poor quality of the imprint samples because of sampling error. False-positive imprint cytology results that lead to an unnecessary axillary lymph node dissection are very rare. Imprint cytology can be recommended for the intraoperative examination of sentinel nodes in breast cancer patients.
Kazuhiko Sato
Sentinel lymph node biopsy (SLNB) is based on the hypothesis that the sentinel lymph node (SLN) reflects the lymph-node status and a negative SLN might allow complete axillary lymph node dissection (ALND) to be avoided. Although the survival outcome is still unknown, this technique has already become a standard of care for breast cancer patients. However, it is still important to discuss current techniques and some controversies. This article reviews these issues for a variety of SLNB techniques.
Hiroyuki Takei, Masafumi Kurosumi, Takashi Yoshida, Jun Ninomiya, Yasutaka Hagiwara, Mari Kamimura, Yuji Hayashi, Katsunori Tozuka, Kimito Suemasu, Kenichi Inoue, Toshio Tabei
Sentinel lymph node biopsy (SLNB) is standard care for patients with early-stage breast cancer, and axillary lymph node dissection (ALND) is considered unnecessary when sentinel lymph nodes (SLNs) are tumor-free. Additional non-SLN metastasis in patients with positive SLNs can be estimated using several risk factors such as primary tumor size, metastatic tumor size in SLNs, lymphatic vessel invasion, and so on. All patients with positive SLNs may be treated with further ALND based on their own risk for non-SLN metastasis. Recent randomized clinical trials have already proved less surgical morbidity and better QOL for SLNB alone compared with ALND. However, trials concerning the efficacy of ALND in positive SLNB patients in preventing local regional recurrence and improving overall survival compared with no ALND, and also, concerning the effectiveness of ALND compared with axillary radiation therapy (RT), have not yielded clear results. The prognostic significance of micrometastasis in SLNs or bone marrow also remains to be determined. So far SLNB is not acceptable for patients with positive nodes in the axilla at initial diagnosis even if their axillary metastases are down-staged to negative by neoadjuvant chemotherapy. Although basically SLNB does not need to be performed for patients with pure ductal carcinoma in situ (DCIS), it is recommended for patients with an initial diagnosis of DCIS which is large, palpable, high grade, or found in younger patients. Because these types of DCIS have higher incidences of accompanying invasive lesions. In addition if patients will undergo mastectomy, SLNB is recommended because of the inability to perform SLNB after mastectomy. SLNB may be acceptable for patients with T3 or T4b tumors, even though SLN identification is lower yet SLN involvement is higher compared with T1 or T2 tumors, and systemic adjuvant therapy is more important for patients with T3 or T4b tumors. SLNB is a bridge to further axillary treatment such as ALND or axillary RT, and which strategy, including no further treatment, is best considered individually based on recurrence risk, treatment responsiveness and use or non-use of systemic therapy.
Keiichi Sotome, Yuki Yamamoto, Atsushi Hirano, Takeshi Takahara, Sayuri Hasegawa, Makoto Nakamaru, Akio Furukawa, Hiroshi Miyazaki, Kyoei Morozumi, Tatsuya Onishi, Yoichi Tanaka, Hisami Iri
Background: Although non-mass lesions on breast ultrasonography have become relatively common, they remain very difficult to diagnose. The purpose of this study was to evaluate the usefulness of contrast enhanced magnetic resonance imaging (MRI) in managing non-mass lesions.Methods: A total of 82 cases of non-mass lesions visible on breast ultrasonography who were subjected to contrast enhanced MRI (CE-MRI) were available for assessment. These lesions were evaluated in terms of the association between the enhancement pattern on contrast enhanced MRI and the pathological or cytological diagnosis.Results: Thirty-three of 82 (40.2%) non-mass image-forming lesions were seen as enhanced lesions on CE-MRI, of which 32 revealed non-masslike enhancements. Of the 19 breast cancers detected as non-mass image-forming lesions, 18 (94.7%) had an enhancement pattern not suggestive of a mass, so breast cancers comprised 56.3 % (18/32) of the lesions. Most of the breast cancers tended to emerge in a setting of duct dilatation with internal echoes (45.5%; 5/11) or low echo areas with indistinct margins (32.4%; 11/34). Morphologically, segmental (57.9%; 11/19) and regional (21.1%; 4/19) enhancements were common patterns of breast cancer which showed up as non-mass image-forming lesions. On the other hand, 49 of 82 (59.8%) non-mass image-forming lesions were not enhanced and 28 of 49 cases underwent pathological examination. Only one case was breast cancer with category 5 microcalcifications and although about half of the remaining 21 cases were followed for at least 12 months, no breast cancers were found.Conclusion: Contrast enhanced MRI was useful for detecting breast cancer in cases of non-mass image-forming lesions. On the other hand, except for cases in which mammography was suspicious for malignancy, lesions showing no enhanced areas may be safely followed, because the possibility of breast cancer is minute.
Masahiro Ito, Takuya Moriya, Takanori Ishida, Shin Usami, Atsuko Kasajima, Hironobu Sasano, Noriaki Ohuchi
Background: Lymphatic vessel invasion (LVI) has been conventionally assessed on hematoxylin-eosin (HE) stained sections, but this assessment tends to be subjective. The aim of this study is to investigate the significance of LVI in invasive breast cancers, primarily using immunohistochemical lymphatic endothelial markers.Methods: We studied 69 invasive breast carcinoma cases. Using D2-40 and podoplanin, we investigated the distribution of lymphatic vessels around the tumor and LVI, and they were compared with the HE sections. The correlation between LVI, lymph node metastasis and disease free survival (DFS) was also investigated.Results: Lymphatic vessels were most frequently seen outside the tumor (86%), whereas lymphatic vessels were not seen in the central zone of the tumor. LVI was found in 22 cases, of which nineteen was seen in the peripheral zone (87%). For both HE and lymphatic markers, the rates of mild LVI tended to be high. The concordance rate between D2-40 and podoplanin was 94.2% (65/69). LVI assessed on HE sections was corresponded to 54/69 cases (78.2%) using either D2-40 or podoplanin. There were 25 axillary lymph node positive cases. Lymph node metastasis significantly correlated with LVI assessed by HE section, but did not correlate with LVI assessed by the lymphatic markers. The tumor recurred in 19 cases during the mean follow-up period of 47.5 months. Disease free survival was significantly better for LVI negative cases on HE analysis, and LVI negative or mildly positive by any staining procedure.Conclusion: The lymphatic endothelium markers, D2-40 and podoplanin, are very useful for detecting LVI, but careful examination by routine HE sections may be enough for routine practice. Moderate or marked degree of LVI may be of value to predict survival.
Takashi Ishikawa, Yohei Hamaguchi, Mikiko Tanabe, Nobuyoshi Momiyama, Takashi Chishima, Yukio Nakatani, Akinori Nozawa, Takeshi Sasaki, Hajime Kitamura, Hiroshi Shimada
Background: Fine-needle aspiration cytology (FNA) is less traumatic and technically easy to apply to small breast tumors.Methods: A total of 382 cases of palpable breast lesions that had undergone fine needle aspiration and histopathologic diagnosis were reviewed with an emphasis on the rate of false positive diagnoses in benign breast lesions.Results: A diagnosis of " malignant " was made in 98 of the 382 specimens (25.6%). The predictive value for malignancy was 97.9%. The sensitivity, specificity, and accuracy of FNA were 86.3%, 98.2%, and 93.2%, respectively, when the " suspicious " group was considered positive for malignancy. The histologic subtypes of the 4 false-positive cases were epithelial proliferative lesions, ductal or lobular hyperplasia. None of these 4 cases were definitely diagnosed as " malignant " by radiological studies. Four false-negative cases by FNA were suspicious for malignancy radiologically. There was no specific pathological subtype associated with false-negative status on FNA in this study.Conclusion: Palpable breast tumors can be definitively diagnosed based on a combination of physical examination, radiological studies and FNA, when the radiological studies concur with the diagnosis by FNA.
Rie Horii, Futoshi Akiyama, Yoshinori Ito, Masaaki Matsuura, Yoshio Miki, Takuji Iwase
Background: To establish tailor-made therapy for breast cancer, we investigated the possibility of predicting chemotherapy sensitive cases based on pre-therapeutic histological features.Methods: A total of 87 breast cancer patients underwent neoadjuvant chemotherapy with a paclitaxel (80mg/m²/q1w, 12courses)or an epirubicin regimen (90 mg/m²/q3wks, 4courses). We investigated the chemo-sensitivity of invasive ductal carcinoma, solid-tubular carcinoma consisting of highly malignant cancer cells with many mitoses. We refer to this type of carcinoma as " chemo-sensitive carcinoma " and compared the histological therapeutic effects of chemo-sensitive and chemo-insensitive carcinomas.Results:1) Out of 87 patients, 20 cases (23%) showed the histological features of chemo-sensitive carcinomas on pre-therapeutic needle biopsy specimens. The remaining 67 cases (77%) were classified as chemo-insensitive carcinoma. 2) Histologically marked or complete response were observed in 50% (10/20) of chemo-sensitive carcinomas and 10% (7/67) of chemo-insensitive carcinomas (χ²=15.33, p=0.0001). Multivariate analysis of chemo-sensitive carcinoma, including HER2, hormone receptor and p53 status, revealed that chemo-sensitive carcinoma had a significant correlation with the histological therapeutic effects (p=0.01119). 3) Pathological complete response (pCR) was achieved in 35% (7/20) of chemo-sensitive carcinomas and 1.5% (1/67)of chemo-insensitive carcinomas (χ²=20.71, p<0.0001). Multivariate analysis revealed that chemo-sensitive carcinoma had a significant correlation with pCR (p=0.0091).Conclusion: The histological features of chemo-sensitive carcinoma were significant predictive factors for chemotherapeutic efficacy.
Tatsuya Yoshimasu, Shoji Oura, Issei Hirai, Takeshi Tamaki, Yozo Kokawa, Fuminori Ota, Rie Nakamura, Yukio Shimizu, Mitsumasa Kawago, Yoshimitsu Hirai, Koma Naito, Megumi Kiyoi, Hirokazu Tanino, Yoshitaka Okamura, Tomoko Furukawa
Background: The dose-response curve for anticancer agents cannot be evaluated by studying patients directly. To investigate individual differences in the dose-response curve for paclitaxel in breast cancer, we utilized the histoculture drug response assay (HDRA) technique.Materials and Methods: Twenty specimens obtained from breast cancer patients who underwent surgical resection were used in this study. The inhibition rates of paclitaxel at several concentrations were measured and fitted to a sigmoid dose-response curve, using non-linear least squares analysis with the fitting equation y=A(1-1/(1+exp(B(x-log(C))))), where A denotes maximal response; B, slope factor; and C, ED50.Results: A dose-response curve was obtained in all tumors. The mean value (±SD) of maximum response, slope factor, and ED50 were 90.2±5.5%, 9.4±4.3, and 36.8±17.2µg/ml, respectively. The slope factor was higher in nuclear grade 3 tumors compared with nuclear grade 1 and 2 tumors.Conclusion: An individual dose-response curve for paclitaxel in breast cancer can be obtained using the HDRA technique. Nuclear grade 3 tumors appeared to have more uniform chemosensitivity to paclitaxel compared with nuclear grade 1 and 2 tumors.
Kenji Yano, Ko Hosokawa, Takeshi Masuoka, Ken Matsuda, Akiyoshi Takada, Tetsuya Taguchi, Yasuhiro Tamaki, Shinzaburo Noguchi
Background: Skin-sparing mastectomy (SSM) is a type of breast cancer surgery presupposed as breast reconstruction surgery. Cosmetically, it is an extremely effective breast cancer operation because the greater part of the breast's native skin and infra-mammary fold are conserved. All cases of SSM and immediate breast reconstruction performed by the senior author during the last five years were reviewed.Methods: There are three implant options for breast reconstruction, namely, deep inferior epigastric perforator (DIEP) flap, latissimus dorsi myocutaneous (LDM) flap, and breast implant, and one of these was used for reconstruction after comprehensive evaluation.Results: From 2001 to 2005, immediate reconstructions following SSM were performed on 124 cases (128 breasts) by the same surgeon. Partial necrosis of the breast skin occurred in 4 cases of SSM. The mean follow-up was 33.6 months. During the follow-up, there was local recurrence following surgery in 3 cases. The overall aesthetic results of immediate breast reconstruction after SSM are better than those after non-SSM.Conclusion: SSM preserves the native breast skin and infra-mammary fold, and is an extremely useful breast cancer surgery for breast reconstruction. SSM is an excellent breast cancer surgical technique. We think this procedure should be considered in more facilities conducting breast reconstruction in Japan.
Hidekazu Kitakata, Kazuo Yasumoto, Yoshiko Sudo, Hiroshi Minato, Yutaka Takahashi
We report a rare case of primary small cell carcinoma of the breast. A 44-year-old woman was admitted to our hospital with a mass in her left breast. Fine-needle biopsy revealed small cell carcinoma with neuroendocrine differentiation resembling small cell carcinoma of the lung. Systemic computed tomography (CT) and magnetic resonance imaging (MRI) revealed no primary site in the lung or any other organ. A modified radical mastectomy with removal of the axillary lymph node (Bt + Ax, R2) was performed. Histological examination revealed that the tumor was composed of small round to oval cells with a large nuclear-cytoplasmic ratio. The tumor cells were positive for neuroendocrine differentiation markers such as synaptophysin, CD56, and neuron-specific enolase (NSE), but negative for thyroid transcription factor-1 (TTF-1), leukocyte common antigen (LCA), estrogen receptor (ER), and progesterone receptor (PR). Interestingly, the tumor cells lacked immunoreactivity for epithelial markers, including cytokeratin AE1⁄3, CAM5.2, and epithelial membrane antigen (EMA). The patient was given adjuvant chemotherapy for axillary lymph node metastasis. There were no signs of recurrence 22 months after surgery.
Shunsuke Tsukamoto, Sadako Akashi-Tanaka, Tadahiko Shien, Kotoe Terada, Takayuki Kinoshita
Background: We encountered two patients with inflammatory breast carcinoma who developed symptomatic brain metastases after achieving local pathological complete responses (pCR) with neoadjuvant chemotherapy (NAC).Case presentations: The first patient is a 39-year-old woman (Case 1), who underwent NAC with AC (doxorubicin + cyclophosphamide)followed by weekly paclitaxel. After achieving a clinical CR (cCR), we conducted a modified radical mastectomy. Pathological evaluation confirmed no residual malignant cells within the breast tissue or lymph nodes. However, she developed neurological symptoms from brain metastases one month postoperatively. The second patient is a 44-year-old woman (Case 2). Again, no residual malignant cells were detected within the breast tissue or lymph nodes following NAC, but the patient developed symptomatic brain metastases eight months postoperatively. When primary breast tumors are locally advanced, it may be worthwhile to rule out brain metastases even if pCR is obtained after NAC.
Masami Kadowaki, Takeshi Nagashima, Hiroto Sakata, Masahiro Sakakibara, Takafumi Sangai, Rikiya Nakamura, Hiroshi Fujimoto, Manabu Arai, Yasuhide Onai, Yuichirou Nagai, Yukimasa Miyazawa, Masaru Miyazaki
Benign epithelial inclusions are uncommonly found in lymph nodes, and ectopic breast tissue in axillary lymph nodes is particularly uncommon. The patient is a 48-year-old woman who had an adenoma of the nipple removed 10 years previously. A swollen lymph node with amorphous calcifications in a clustered distribution on mammogram was found in the left axilla. Fine needle aspiration cytology showed only cystic change. Excisional biopsy was performed and microscopic examination demonstrated that the node contained benign mammary epithelial and glandular inclusions, and no evidence of malignancy.Such cases will be increasingly found due to the widespread use of mammography screening and biopsy of axillary sentinel lymph nodes. Ectopic breast tissue in lymph nodes may be mistaken for malignant lesions. It is most important to identify correctly the epithelial inclusions in lymph nodes to prevent an erroneous diagnosis.
Hajime Hikino, Koji Kodama, Kiyoshi Yasui, Nobuhiro Ozaki, Saburo Nagaoka, Hiroshi Miura
A case of an intracystic adenomyoepithelioma of the breast mimicking intracystic carcinoma is described. Preoperative examination with mammography, sonography, computed tomography, and magnetic resonance imaging showed an intracystic tumor with an indistinct margin and several swollen lymph nodes in the ipsilateral axilla. Because the results of fine-needle aspiration cytology of the tumor were interpreted as carcinoma, partial mastectomy with dissection of the axillary nodes was performed. Histopathologic and immunohistochemical examination revealed an intracystic adenomyoepithelioma without nodal involvement. The imaging features of this rare tumor may vary widely, which may result in an incorrect diagnosis of breast carcinoma. Indeed, adenomyoepithelioma has metastatic potential; however, lymphatic spread is rare and axillary intervention may be over-treatment for most cases. While the imaging descriptions of intracystic adenomyoepitheliomas are very limited, this tumor should be considered in the differential diagnosis to avoid unnecessarily aggressive treatment.
Naruto Taira, Kenjiro Aogi, Shozo Ohsumi, Shigemitsu Takashima, Susumu Kawamura, Rieko Nishimura
Epidermal inclusion cysts are uncommon in the breast, but the consequences can be severe when these cysts occur in the breast parenchyma. Here, we report two such cases. The patient in case 1 was an 85-year-old woman with a 3-cm palpable mass in the right breast. Mammography revealed a round and smoothly outlined mass, which indicated a benign tumor, and sonography showed an irregularly shaped and heterogeneous hypoechoic mass. Breast cancer was suspected on the basis of the sonographic findings and the age of the patient, but excisional biopsy revealed an epidermal inclusion cyst. The patient in case 2 was a 45-year-old woman with a 9-cm lesion in the left breast. Mammography revealed a round, dense, smoothly outlined mass, and sonography showed a well-defined, central hyperechoic mass. A phyllodes tumor or a giant fibroadenoma was suspected on the basis of clinical and imaging findings, but the resected specimen revealed an epidermal inclusion cyst.
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Posted on May 10, 2012
Cal U will stream live video of graduate and undergraduate Commencement ceremonies so families and friends can watch from anywhere in the world. See our graduate ceremonies at 7 p.m. Friday; watch undergraduates at 10 a.m. Saturday. Read more.
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Mahnomen County Sheriff's Deputy Chris Dewey remains in satisfactory condition, hospitalized at MeritCare Hospital, 801 Broadway, Fargo, N.D. It is planned that he will be transferred to Craig Hospital, a rehabilitation hospital specializing in brain and spinal cord injuries in Denver, later this week.
New photos of Chris will be released to the media tomorrow and the media will be allowed to get footage of Chris leaving the hospital later this week. Details will be communicated to the media once the transfer date has been set.


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LAHORE, Sept 20: The provincial police chief posted on Thursday two senior police officers, including the SSP (operations), in the provincial capital.
According to a notification, SSP Capt Sohail Chaudhry (retired) has been posted as Lahore Chief Traffic Officer against an existing vacancy.
Punjab AIG (Administration) Sohail Akhtar Sokhaira has been transferred and posted Lahore SSP (Operations) against an existing vacancy.
SSP Ahmad Kamal has been posted in Sokhaira's place.
SSP Chaudhry, who has recently returned from the UK after completing his master's in criminology from the University of Cambridge, was working as City Traffic Police SP (Headquarters). — Staff Reporter


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What are hub rings and are they required on my wheels?
To understand centering rings you must first understand what a centre bore is. Centre bore refers to the centre hole in the wheel that centres the wheel on the hub of the car. Most alloy wheels are mass-produced, and have a large center bore to accommodate several different vehicles. If this is the case, a hub ring (also referred to as centering rings) will help ensure you are properly centering your alloy wheel on the hub of the vehicle. Steel wheels are usually built in a variety of sizes and are meant to fit your vehicle exactly, so they do not use hub rings.
Hub rings are hard plastic or metal rings that fit between the wheel's centre hole and the vehicle's hub. They make your centre hole smaller so that it will fit your vehicle's hub tightly, minimizing the risk of an off centre, and thus unbalanced, wheel. Without hub rings, tires may vibrate because the wheel may not be precisely centred on the hub.


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Lee Trevino Net Worth
Net Worth: $40 Million
- Birth Place Dallas, Texas
- Full Name Lee Buck Trevino
- Nationality Mexican American
- Date of Birth December 1, 1939
- Occupation Professional golfer
About Lee Trevino
Mexican American professional golfer, Lee Trevino has an estimated net worth of $40 million. He has won six major championships over the course of his career, considered an icon for Mexican Americans, and has been nicknamed "The Merry Mex" and "Supermex". He joined the U.S. Marine Corps when he was 17 and served for four years. He played golf while he was enlisted at Armed Forces golf events in Asia. Fellow soldier Orville Moody who was a rival of Trevino played against him in the PGA Tour in the late 1960's. Lee was the winner of the Vardon Trophy in 1970, 1971, 1972, 1974, and 1980, as well as the winner of the Jack Nicklaus Trophy (Champions Tour) 1990, 1992, 1994, the Arnold Palmer Award (Champions Tour) 1990, 1992, and Rookie of the Year (Champions Tour) 1990. He worked for NBC television as a color analyst from 1983 until 1989 for the PGA Tour. Many non-golf fans will recognize Trevino from his roll in Adam Sandler's movie Happy Gilmore, as the head shaking guy.


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For all those Mad Men fans out there, did you know Jon Hamm does comedy? After four seasons as the impenetrable Don Draper it was a surprise to see Hamm exploring his comic side on episodes of Saturday Night Live and scene-stealing recently in the big screen hit Bridesmaids. Universal execs liked the money they made off Bridesmaids so much that they've green-lighted another film by director Paul Feig and producer Judd Aptow who are rumored to be considering Hamm for a role. Check out Hamm unleashed in this conversation with fellow funnyman Conan O'Brien:
Tags: Bridesmaids, Conan O'Brien, John Hamm, Judd Aptow, Mad Men, Movies, Paul Feig
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Opinion articles 2011
Racism – Europe's Common Problem
Since the terrorist attacks in Oslo and Utøya, countless foreign media have sought my opinion. They all ask the same questions: What will happen in Norway now? Will Norway be recognisable after this? Could something similar happen in other countries? At first, I answered that Norway will be...
A new era for privacy by Thorbjørn Jagland
New media are challenging the traditional boundaries of data protection. This year's Data Protection Day – 28 January – takes place against a backdrop of international controversy, with debate raging on the rights and wrongs of Wikileaks, users of social media waking up to the privacy pitfalls of...
Thorbjørn Jagland : Democratic Security and Respect for Human Rights in the 21st century
Europe has witnessed dramatic changes in recent years , which gave Europe more peace and unity than ever before in its history, as well as a constant economic growth which - combined with a colossal technological revolution - afforded to European societies an unprecedented high level of...
Conference on the protection of human rights of refugees, asylum seekers and migrants
High-Level Conference of Ministers of Justice and representatives of the Judiciary "Strengthening Judicial Independence and Impartiality as a Pre-condition for the Rule of Law in Council of Europe Member States"
Award ceremony of the European Civil Right Prize of Sinti and Roma


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18 October 2012
Syngenta congratulates the 23 Thought for Food Ambassadors who have been selected from top universities around the world to attend One Young World, which takes place in Pittsburgh, USA from October 18-22, 2012.
Thought for Food (TFF) is a one-of-a-kind competition sponsored by Syngenta in cooperation with the Sandbox Network, iStrategyLabs and One Young World. Piloted in 2011 to universities in Europe, TFF went global in 2012. From March until June 2012, talented students from universities in countries as diverse as Canada, Korea, India, Nigeria, Uganda, the UK, the USA and Taiwan were called on to find bold solutions to the biggest challenge facing their future – how to feed 9 billion people.
Each university brought together a cross-disciplinary team of up to five students, representing a breadth of knowledge and experience. They looked into the deepest challenges surrounding food security, and were expected to push boundaries, merge their creativity and imagination, and develop visionary ideas that educate, inspire and empower people to build a healthier, more sustainable planet. With the help of peer mentors, each team developed a robust business plan to help bring their big ideas to life. From campus awareness campaigns and smartphone apps to agriculture reality shows, virtual games and educational urban gardens - the projects generated by the TFF student teams are not only grabbing people's attention, they will also help to change the world.
From over 50 entries, a panel of expert judges has selected two student teams from IIT Roorkee (India) and Texas A&M University (USA) as winners of the 2012 Thought for Food (TFF) global challenge. The winning project from the team in India is a comic series and web-based educational multiplayer video game to manage challenges such as food waste. The winning idea from the US team is an "eco-park" model which explains food systems in both a physical and online space.
The two teams won a trip to One Young World – the premier global forum for young leaders. In addition, Syngenta also sponsored runner-up teams from Korea, Uganda and Canada to attend the event. There, the students will join other young delegates from over 150 countries, CEOs from some of the world's most influential companies and inspirational global leaders, such as Kofi Anan, Mohummed Yunus, Bill Clinton, and Archbishop Desmond Tutu.
For more information on the TFF challenge and the winning projects, please check the attached slides.
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Tel: +41 61 323 2323
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New York City has been closing Park Avenue to cars from 72st to the Brooklyn Bridge on Saturday mornings this month. My wife & I rode our Bob Jackson tandem on it yesterday. Got on Park Ave. at 71st St. around 9:30 & rode south & over the Brooklyn Bridge, then north to the Williamsburg Bridge, over that, then wound our way through the LES to the Village & back up Lafayette to Park & 71st. Mostly fun, lots of bikes, though less crowded on Park than I'd feared. Some of the construction zones were a bit hairy due to narrowing the street and some considerable variation in riders' speed and skill.
It was certainly worth doing: any city-sponsored bicycle-centric event should be supported, and it is always nice not to have to deal with cars for long stretches of time. The police and volunteers were well-trained, polite and effective, and the vibe was calm and upbeat. Definitely not an event for paceline types or scenery junkies, or folks who hate crowds, but for building up urban riding chops on a tandem with minimal dues for screwing up, it suited us just fine.


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Indiana will be short its center against the Clippers' talented frontcourt.
USA Today Sports
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Posted by Ibchris81 3 years ago
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"LOL, boston what a red neck....."
Play - Baltimore w/Wilson vs.McHugh.
Edges - Orioles: Tyler Wilson 4-1 away career team starts; and 2-0 away with 3.75 ERA and 1.08 WHIP this season. Astros: Colin McHugh 0-3 team starts versus A.L. East foes this season, and 5.13 ERA and a 1.59 WHIP this season.
With Houston just 11-22 at night this season, and the Orioles 21-10 under the lights at night this campaign, we recommend a 1* play on Baltimore. Thank you and good luck as always.
> It doesn't get any better than this - Marc's red-hot top rated 10* NBA Playoff Game Of The Week and it goes Wednesday night in the Cavs-Raptors Eastern Conference finals showdown. If you're serious about winning you know exactly what to do!
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The Computer History Museum recently held a retrospective on Plato and the videos of that entire conference are now available here. While you are there, do check out the rest of the videos on the Computer History Museum YouTube channel. There are currently a legion of artifacts, with everything from historic computer films from the 1950 and 1960 decades, to museum lectures and panels, exhibit films, and co-production pieces.
Quote of the day:
E. B. White
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Minority Nursing Pool Grows With Push From Universities
Demand for bilingual and bicultural nurses has skyrocketed in recent years, propelled by the swelling number of immigrants—especially Hispanics, who represent about 15 percent of the country's total population but only 2 percent of all registered nurses.
"I'm not too worried about not being able to find a job," Huerta says. "I'm sure something will come up."
She has every reason to be confident. Nurses are in high demand, particularly ones with bilingual skills.
The gap between the number of job vacancies and the scarcity of registered nurses is wider than ever, says Cheryl Peterson, senior policy analyst at the American Nurses Association in Washington.
The demand for bilingual and bicultural nurses has skyrocketed in recent years, propelled by the swelling number of immigrants—especially Hispanics, who represent about 15 percent of the country's total population but only 2 percent of all registered nurses.
Huerta, who was born in Mexico and speaks fluent Spanish, will have an advantage over many of her classmates when in comes to negotiating job offers.
"There is no doubt that the scarcity of nursing professionals is widespread," Peterson notes. "But the shortage of bilingual nurses is one of the hardest-hit areas."
Fortunately for recruiters, several schools are emphasizing a need for bilingual nurses. Carroll College, nestled in Waukesha in the heart of America's dairy land, created the Hispanic Nursing Project in 2004. The initiative provides grants and other academic support to students who are bilingual or bicultural, says Dee Dee Wallace, program coordinator.
Huerta was one of the first students to enroll in the Carroll program. Similar initiatives have popped up across the country, including at Washington State University and the University of Texas at El Paso.
It promises not only to ease talent shortages but create more fertile ground for recruiting. Talent acquisition in the health care industry must take into account several important considerations.
For one, long-distance recruiting likely won't pay off, since nursing graduates are generally not willing to relocate.
"Nurses like to stay local," says Angie Millan, president of the Los Angeles chapter for the National Association of Hispanic Nurses. "I graduated in Los Angeles and have been working in the community for more than 20 years."
What's more, the programs are relatively small, which is not surprising given the limited pool of qualified students, Millan notes. Against this backdrop, she stresses the importance for recruiters to develop personal relationships with the potential candidates.
"Having an understanding who these individuals are and what their needs are will be critical in recruiting them," she says. Millan recommends that companies be as generous as possible with flextime benefits.
"Many Hispanic nurses have families and small children to take care of," she says. "Flexibility may mean more to them than salaries sometimes."
Recruiters should also keep in mind that accessing students in these programs may require a certain amount of cold-calling and networking.
"The nursing industry does not have many central databanks," Peterson says. "Information is often fragmented and won't necessarily be listed on the Internet."
A good starting point for recruiters is to call their local nursing schools to find out whether they offer special initiatives.
Programs like the Hispanic Nursing Project serve several critical purposes, Peterson notes. For one, they are developing a new generation of nurses who can meet the health care needs of the country's growing immigrant population. Further, they are increasing diversity within the nursing profession, something that is needed since more than 97 percent of nurses are white females, Peterson explains.
Another Wisconsin school, Marquette University in Milwaukee, launched the Beyond Project, which provides financial grants and leadership development support to individuals from under-represented backgrounds who want to major in nursing. This means targeting not only Hispanics but also African-American and Asian students, according to Terrie Garcia, the project's coordinator. The Beyond Project also offers mentoring and leadership training to help minority nursing students develop the skills necessary to become future decision-makers in the health care industry.
For the moment, however, Huerta is focused on completing her studies. The job hunt is secondary. It's probably a wise strategy, considering the Bureau of Labor Statistics is projecting that 587,000 new jobs will be added for registered nurses between 2006 and 2016.
"This is a good time for me to be on this path," she notes. "I'll be able to help others and to have a secure professional future."


text:
Originally Posted by God
i mean, me and pokemastersean13. look at me, still so attached to his memory, i mistake him for current pd members ... so desperate am i to imagine he is still among us.
I know God, I know. I really wish I got to know him before he ODed.
Originally Posted by Fox
I thought you and Mario used to insinuate PMS and I were in love...?
Show us some pics.
Your an absolutely wonderful man, any girl that is yours is lucky and I know that from personal experience. ~KMT
Forum Rules


text:
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text:
Nutritional Healing for Cataracts
|Thyroid Home Self Test
Balance The Functioning Of This Vital Gland
According to many researchers, including eye doctor and nutritional expert Dr. Gary Price Todd, at least three eye diseases are associated with hypothyroidism (under-functioning thyroid): macular degeneration, diabetic retinopathy, and glaucoma. Along with the effect it has on the eyes, it can also contribute to many other physical ailments and diseases (see the list below).
In our experience, virtually everyone with any of these conditions is hypothyroid and could potentially improve when the thyroid functioning is balanced. Prevention of further visual decline is possible and our experience is that people can also regain some degree of lost vision.
Detailed instructions show you a simple way to check the functioning of your thyroid - in the privacy of your own home. Easy to follow and takes just a few minutes a day. Armed with this important information, you'll be better able to not only talk with your doctor, but also do something good for yourself - and your vision.
Thyroid Home Self Test
Step-by-step Instructions & Supporting Information
An under-functioning thyroid gland can also produce these symptoms
(A deficiency of the nutrient in parentheses may also cause the same symptom. Mg is Magnesium; A is Vitamin A; and Q-10 is Co-Enzyme Q-10.)
Lack of energy (Mg)
© MMXIII Cambridge Institute for Better Vision | Terms of Use | Privacy Policy | Affiliate Program
|Built upon a holistic approach, the solutions described on this web site offer self-help alternatives for people who want to better their vision, minimize the use of glasses or contact lenses, enhance perceptual skills and/or develop emotional clarity. The information on this site is not meant to diagnose or treat any medical conditions of the visual system. Anyone with a medical disorder or persistent problem is advised to consult an eye doctor or other health care practitioner.
Individual results may vary, and testimonials are not claimed to represent typical results. All testimonials are by real people, and may not reflect the typical purchasers experience, and are not intended to represent or guarantee that anyone will achieve the same or similar results.
TESTIMONIALS: User experiences and testimonials on this site reflect their individual experience. Because others have had positive experiences does not necessarily mean that you will have the same, similar or any results. Everybody is different and so are your eyes, so you may have a totally different experience. Any reference to "guarantee" refers to our 100% Money Back Guarantee and not to any specific results from our products.
These statements have not been reviewed by the Food and Drug Administration. The products are not intended to diagnose, treat, care or prevent any disease. See your eye care professional regularly.


text:
Last Marine takes command in Afghanistan
Camp Pendleton brigade replaces southwest force at war's end
A Marine brigade from Camp Pendleton took command of coalition forces in southwestern Afghanistan as the 13-year campaign enters its critical final phase, the International Security Assistance Force announced Thursday.
Brig. Gen. Daniel Yoo, commanding general of Marine Expeditionary Brigade-Afghanistan, took charge of U.S. and international forces in Helmand and Nimruz provinces during a transfer of authority ceremony Wednesday at Camp Leatherneck.
Yoo is expected to be the last NATO commander in the Southwest before the international combat mission in Afghanistan ends this year and Afghan forces assume full responsibility for securing the country.
He replaced Maj. Gen. Lee Miller, the Camp Lejeune, N.C., Marine who spent a year in command of the region and 2nd Marine Expeditionary Force (Forward).
The Marine force in the Southwest has already dwindled toward 4,400, down from a wartime high of more than 20,000.
The next 120 days, including the April 5 presidential elections, are crucial to longterm prospects for stability in Afghanistan, according to Lt. Gen. Mark Milley, commanding general of International Security Assistance Force Joint Command.
"This ain't over for a long shot. … This is the most decisive period in the entire war as we prepare the Afghan security forces for the upcoming elections, and we transition the political government of Afghanistan," Milley said at the ceremony, according to a report by Marine Staff Sgt. John Jackson.
"When that happens, it will be a mortal death blow to the enemies of Afghanistan. You've got your work cut out for you," he told Yoo.
In the frigid morning cold, Yoo said: "Today's transfer of authority ceremony marks a significant transfer of the mission, a very important mission and enormous responsibility." One that holds his command accountable to the international coalition, their Afghan hosts and counterparts, "and to all our fellow service members who have sacrificed over the course of the campaign."
Helmand province, a poppy-growing region in the Pashtun heartland of the country where the Taliban originated, has been the deadliest area of the country for coalition troops during the war.
Of the 3,417 international troops killed in Afghanistan since the 2001 U.S. invasion, 944 were fatally wounded in Helmand province, according to icasualties.org, an independent website monitoring NATO casualty releases. The second-deadliest province has been neighboring Kandahar, with 544 fatalities.
U.S. and international casualties dropped steeply in the last year, as Afghan troops took the lead for security throughout most of the country. During Miller's command, 19 coalition troops were killed and more than 300 wounded in the Southwest as Afghan forces took over most combat patrols and the U.S. withdrawal gathered pace.
During their first summer fighting season with limited support from coalition troops, Afghan national troops overmatched enemy forces despite intensifying insurgent attacks in some areas and held all major population centers in the Helmand river valley, U-T San Diego learned during a Christmas visit to the region.
The outgoing Marine command, along with its coalition and Afghan partners, reduced violence by 20 percent over last year and 46 percent over the last two years in what was "far and away the most violent place in all of Afghanistan," Milley said. (Details of the attack statistics were not reported.)
"What you have done over the course of a year here has made huge progress in security. But really what you've done is assisted the 215th Corps and the Afghan National Police in creating a shield beyond which the people of Afghanistan will have some hope for the future."
The North Carolina Marines are heading home with a sense of accomplishment, and gratitude for their Afghan and coalition partners. "To all those who served with me out here, to the eight nations who did an incredible job, I want to wish you God bless and thank you very much," Miller said.


text:
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Get a FREE Body Composition Analysis during your first consultation.


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text:
- Quick links:
BUFFALO -- General manager Ray Shero does not know how many players the Penguins will have on their roster when they open the 2006-07 season Thursday against Philadelphia.
He isn't sure how that still-to-be-determined group will break down by position, either. Whether his club will carry 12 forwards or 13. Six defensemen or seven. Two goalies or three. Or any combination thereof.
Perhaps, the only thing of which he seems reasonably certain is that the team the front office and coaching staff settle on during a meeting today won't necessarily be the best 21 or 22 or 23 players to come out of training camp. that would be ideal, of course, but he acknowledged that off-ice factors -- like whether one job candidate must clear waivers if he is sent to the minors while another doesn't -- cannot be ignored in the decision-making.
"It's like managing your roster," Shero said.
Twenty players, including all the young players competing for jobs, got a final opportunity to impress management last night, when the Penguins closed out exhibition play with a 4-2 loss to Buffalo at HSBC Arena.
Goalie Marc-Andre Fleury, lackluster throughout training camp, responded well to that challenge, stopping 25 of 28 shots.
"He played well," coach Michel Therrien said. "He was sharp, was solid. ... He was square to the puck and didn't panic."
Shero said the group that will assemble the roster -- he'll be joined by Therrien, assistant coaches Mike Yeo and Andre Savard, assistant general manager Chuck Fletcher and senior advisor Ed Johnston -- figures to face "two or three" truly difficult decisions.
The most intriguing might be in goal, where Fleury, Jocelyn Thibault and Dany Sabourin are competing. Much that Shero said yesterday gave the impression the Penguins are likely to start the season with two goalies, not three, although he said that is "not 100 percent" yet.
If the Penguins don't keep three, they must either demote Fleury, their long-term go-to guy who does not have to clear waivers, or risk losing Sabourin or Thibault when they are sent down.
The Penguins have 27 healthy players on their roster, which means they must pare at least four to reach the league-mandated maximum of 23. Winger Ronald Petrovicky (hip), defenseman Eric Cairns (knee) and center Evgeni Malkin (shoulder) are candidates to start the season on injured-reserve and would not count against the 23 until they are healthy.
Petrovicky is a lock for IR, Cairns figures to end up there and Malkin is iffy enough that a decision on him might not be made until the Penguins submit their roster to the league office Tuesday.
Malkin skated during the Penguins' game-day workout yesterday, stickhandling gingerly and flipping easy wrist shots. Shero said he hopes to have an idea of when Malkin might resume playing by "the tail end of the week."
The current 27-man roster includes two junior players, center Jordan Staal and defenseman Kristopher Letang, who do not have contracts.
Shero confirmed that he's negotiating with the agents for both, however, with the goal of having deals in place by the 5 p.m. deadline tomorrow.
If Staal and Letang are not signed by then, they must return to their junior teams. If they get contracts, both could play up to nine NHL games before going back to junior, and that time with the Penguins would not count toward the expiration of their contracts or their eligibility for free agency.
"If we can get them signed by 5, great," Shero said. "If we can't, they'll go back, and we'll continue to work at a later date. These two guys will be brought under contract at some point."
Getting a contract isn't synonymous with getting a roster spot, though. Shero seems inclined to keep his roster below the league limit, in part to give him flexibility to claim someone off waivers.
"[Carrying 23] wouldn't be my choice," he said. "We only have nine games in October. My preference would be 22, plus IR, or maybe 21, plus IR, quite honestly. Maybe we'll just carry one extra guy to start. I want to be smart about it."
NOTES -- Michel Ouellet and Ryan Malone scored for the Penguins, who finished the preseason 2-2-3.
Dave Molinari can be reached at firstname.lastname@example.com .


text:
OS: Centos 6.4 OpenLDAP: 2.4 Mac: 10.8.3 through 10.8.4
I have an OpenLDAP server and I'm able to have users authenticate, however, for some reason even though I've changed the Mappings of NFSDirectory to apple-home-userDirectory and pointed it to the correct /Volumes/Users/ it will not create their home directory.
Things I've tried;
I tried commenting out /etc/auto_master and it did not work.
I tried using #/Users/$uid as the mapping, which, did work -- because it simply tells it to ignore the LDAP Home Directory attribute, but I noticed that the resulting behavior was quirky -- as in, if I went to System Preferences > Users & Groups, I was unable to see anything.
Is there a way, like with AD, that you can force it to create a local directory?
I figured this applied as a server question as well, since I have to make changes in both places. I mean, it seems like there is plenty on OpenLDAP + NFS, hardly anything on Open LDAP + Local Directories.


text: In a yellow pages ad, that just came out today, one photographer prominently uses the PPA Certification logo. This person is not listed on the Certified Photographer website nor is the photographer noted as being certified on the PPA.com site. Does anyone know how long after certification it takes for this credential to be listed on these websites? Perhaps these credentials haven't "shown up yet" on the sites, maybe, but if someone isn't certified and yet advertises themselves as such what can happen?


text:
May 27, 2016
LONDON (AP) -- Sabine Lisicki advanced to her first Wimbledon final a couple of hours after Marion Bartoli reached her second.
Lisicki was a 2011 semifinalist at the All England Club. She beat fourth-seeded Agnieszka Radwanska 6-4, 2-6, 9-7 Thursday on Centre Court, overpowering her opponent at the start and then hanging on at the end.
Bartoli also asserted control early on, but she never let up in a 6-1, 6-2 victory over Kirsten Flipkens.
Bartoli reached the Wimbledon final in 2007, losing to Venus Williams in straight sets.
None of the four semifinalists at this year's tournament has won a Grand Slam title.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


text:
lol, multiple girls like me right now.
lol, multiple girls like me right now.
Apparently, your parents were really repedative the night you were conceved, because you like to repeat yourself a lot.
Well, you got me there.
Don't like sex with men like I do?
Wow, recovery will be rough.
I need rehab.
you said it not me. multiple times in your short forum life have you talked about wanting gay sex. you brought it on yourself. and rehab? are you saying being gay is wrong? someone should be outraged right there, find me a political group or some college kids.
Rehab, recovery from the extremely battering insults.
I'm broken inside, oh goodness, the pain.
Oh, woe is me and whatnot.
If you're going to try to insulst someone to death, I have one tip.
You are pathetic.
hahahaha damn bitch quit cryin. callin me pathetic yet you're the one trying to ungay. you turn your friend gay, she brings you here and now you totally avoid how you said gay was wrong and you call me pathetic. cry more! waaaaaaah
Crobat Master, thank you.
I can now, in times of hardship, think to myself, "At least I'm not CM."
Thank you, you have saved me.
thinking you arent me will bring tears to your eyes. you'd like to have the ability to actually get in someones face and have some testicles. do you cry after orgasm too? you seem like the type. not tears of joy though
Haha, CM!
Your insults are terrible!


text:
Red Hill Studios is using the motion technology found in the Xbox 360 and Wii consoles to help people with Parkinson's disease improve their gait and balance. Researchers have used the technology to help stroke victims in a similar fashion, so aiming the technology at other afflictions makes perfect sense. Red Hill is collaborating with the UCSF School of Nursing to develop the game.
The clinical team members at UCSF are focusing on specific body movements and gestures that their research has shown slow down the physical declines of Parkinson's. Using that research and working closely with UCSF clinical team members, Red Hill has created nine games so far. The results have proven to be fairly effective too. Over half of the subjects in a three-month research project showed small improvements in walking speed, balance and stride length. 65 percent of players demonstrated longer stride length; 55 percent showed signs of increased gait velocity, and 55 percent reported improved balance confidence after playing the games for 12 weeks.
"Each subject found his or her own gaming 'sweet spot' – the spot where the physical challenge was not too hard, not too easy, just right,'' said Bob Hone, creative director of Red Hill Studios and the lead Principal Investigator of the study. "And when subjects mastered one game level, they often moved on to harder levels for more beneficial effect. The subjects improved their games scores while improving their gait and balance.''
In order to boost the effectiveness of the game-based therapy and to track how well it worked, Red Hill developed a custom sensor suit with nine tracking sensors to analyze subjects' movements with higher resolution and accuracy than what's currently possible with standard gaming platforms.
Hopefully we'll hear more about advances in the game-based therapy technology in the months ahead.
Source: IndustryGamers


text:
Log in
About the WSBB
Welcome to the official home site of the Wirral Schools Brass Band. The band which has been running for over 40 years still continues to entertain the public with its music as well as offering a rich learning environment for its members. This site contains information for future performances as well as a sample and taste of what the band is about. This site has been commissioned and is maintained by the band's Parent Association who work in support of the Wirral Schools Music Service. Don't forget to go to the news page!!
Whit Friday success again-24/05/2013
The band took the annual journey along the M56 to take part in the Whit Friday march contest. The band again this year won prizes for their performances. The final tally for the evening was first prize at Heyrod, first prize at Tame Valley and a second prize at Denton. Well done everyone we are very proud of you.
Alan Milnes
The band
Created by
Juliand Web designs
- Copyright 2011


text:
Kerrey Proposes Cuts
Nebraska U.S. Senate candidate Bob Kerrey says deep cuts and some tax increases would put the federal budget on a path to being balanced, and he argues Republican Deb Fischer hasn't explained how she would reach deeper reductions. Kerrey, a former senator and governor, proposed Thursday cutting $409 billion over 10 years. The Democrat's goal is to shrink spending from 24 percent of the nation's gross national product to 21 percent. He says he doesn't support raising tax rates but backs eliminating some deductions. Fischer has called for spending only 18 percent of GDP. Kerrey says such a reduction would "savage rural health care in Nebraska."
On Air
10am - 2pm


text:
Kapalua now in a different golf landscape
KAPALUA, Hawaii Paradise can leave a lasting impression.
Steve Stricker was just starting to pull himself out of a deep slump in 2006 when he was reminded by his daughter, Bobbi Maria, how long it had been since he last won on the PGA Tour. She was 8 at the time and won a tournament for juniors at their home club in Wisconsin, no more than three or six holes.
"She comes home all excited and says, `Daddy, I won, I won! We're going to Hawaii,'" Stricker once recalled.
He had to break the news to her.
Stricker was the one who had to win a tournament for them to go to Kapalua to start a new season, and he did that the following year.
As traditions go in golf, starting the year on the rugged coast of Maui is relatively new. The Tournament of Champions began in Las Vegas in 1953, moved to La Costa Resort north of San Diego in 1969 and stayed there 30 years until coming to Kapalua.
This was the 15th year the tour has started at Kapalua, and there has never been another year like this one. A tournament that was supposed to end on Monday didn't start until Monday because of three days of powerful wind - one gust measuring 48 mph - that had the locals drawing comparisons with a 100-year storm.
About the only good that came out of such freak weather was that it took attention away, however briefly, from the PGA Tour winners who stayed home and missed out on the endless days - the top four players in the world ranking, for starters, led by Rory McIlroy and Tiger Woods.
It's not a new problem, but it's still a problem. And it contributes to a future as cloudy as Molokai at sunrise.
Kapalua has a contract only through this year to host the tournament.
Hyundai's three-year deal as the title sponsor of the Tournament of Champions expires this year, even though corporate officials sounded optimistic about renewing and there are strong signs it will happen.
It doesn't help that Mother Nature was in a bad mood this week. Few things in golf cause a knee-jerk reaction like bad weather.
There were suggestions to move the Pebble Beach National Pro-Am to the end of the West Coast Swing after the tournament was canceled by rain in 1996, completed nearly seven months after it started in 1998 because of rain, and shortened to 54 holes a year later because of - you guessed it - rain.
Since then, Pebble has had more than its share of glorious weather.
The rain was so bad in California in 2005 that the Nissan Open at Riviera went five days to get in 36 holes. The next week, the Match Play Championship at La Costa was postponed one day because the entire course looked like a water hazard. Woods wondered if it might not be better for the PGA Tour to spend February in Florida and March in California. It sounded like a reasonable idea until a Champions Tour in Florida was shortened to 36 holes because of rain.
Wiser heads will realize that golf is an outdoor sport. It's not a disgrace when weather causes problems. It's a miracle it doesn't happen more often.
The issues on Maui go beyond weather.
The PGA Tour is going to a wraparound season in the fall, meaning the real season-opener will be in October at the Frys.com Open. There already will be six tournaments in the books before the Tournament of Champions next January.
Is that a problem? Not when you consider that for 33 years, the Tournament of Champions was held after the Masters.


text:
All statements involving Michael J. Gardiner
After the 9/11 terrorist attacks grounded commercial air traffic, "there was a temperature drop while the airplanes weren't flying, for the week afterwards."
— PolitiFact Rhode Island
"It costs us, logistically, three times more to fight in Afghanistan than it does in any other place."
— PolitiFact Rhode Island
U.S. Rep. Jim Langevin didn't want a border fence to block illegal immigration "because he is afraid that someone will get hurt trying to go around the fence."
— PolitiFact Rhode Island


text: Dr. Murray received her medical degree in 1994 from the University of Texas Health Science Center in Houston where she also performed her internship. She completed her residency training in Ophthalmology at St. Vincent's Hospital, New York, New York, and a fellowship in Cornea, External Disease, and Refractive Surgery at Houston Eye Associates, Houston, Texas. She is board certified in Ophthalmology.


text:
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So what have we learned for this season?
Battle will be between Lorenzo & Stoner, with Pedrosa picking up a few in-between.
Cal & Dovi the best of the rest.
The others fighting over the crumbs.
Rossi nowhere (how long can this go on before Ducati fire this lemon???)
CRT bikes hopeless and a boring as hell ... the only slight glimmer of interest being how often Edwards or DePuniet can beat Rossi.


text:
Tom Ka Gai Coconut Chicken Soup
This Thai chicken soup from Biggest Loser chef Cheryl Forberg is made with light coconut milk.
- 2 teaspoons canola oil
- 3 tablespoons minced fresh Thai ginger (galangal) or regular ginger
- 3 tablespoons chopped shallots
- 2 stalks fresh lemongrass (bottom 4 inches only), peeled, halved lengthwise, and thinly sliced crosswise
- 2 1/2 cups fat-free, low-sodium chicken broth
- 1 (14-ounce) can light coconut milk
- 1/4 cup Thai fish sauce (see note)
- 1/4 cup lime juice
- 12 ounces boneless, skinless chicken breast, diced
- 1 cup thinly sliced mushrooms, preferably shiitakes
- 1/2 cup carrot matchsticks
- 2 tablespoons thinly sliced scallions
- 1 tablespoon chopped cilantro
- In a 3-quart saucepan, heat the oil over medium-high heat. Add the ginger, shallots, and lemongrass and cook for about 1 minute, or until fragrant.
- Carefully add the broth and coconut milk. Bring to a boil. Reduce the heat to a simmer, add the fish sauce and lime juice, and return to a simmer.
- Add the chicken, mushrooms, and carrots to the broth and cook for 3 minutes, or until the chicken is just cooked through.
- Remove from the heat. Garnish with the scallions and cilantro and serve hot.
Note: Fish sauce, also called nuoc mam, is available in Asian markets, specialty foods stores, and some supermarkets.
Source: Flavor First by Cheryl Foberg. Copyright © 2011 by Cheryl Forberg. By permission of Rodale, Inc. Available wherever books are sold.


text:
About Us
We are an 8,000 sqft indoor playground with an attached cafe for parents and 3
private party rooms for your special celebrations. Our structure features
interactive dance floors, climbing, crawling and a variety of other activities
meant to stimulate your children. We have a separate toddler area and a
main area that is recommended for children up to 14 years of age.
Parents are always welcome to assist their children and are never charged an
admission fee.


text:
oklahoma-city Articles
Things to Do, Travel Tips, & Advice
Oklahoma City Mythbusters
by Shawn S. Lealos. Posted Sep 23rd 2010 08:12 PM
Continue ReadingOklahoma City has its fair share of scary urban legends from monster myths to ghost stories. Oklahoma City mythbusters have explored the creepy tales to come up with the most popular urban myths from the state of Oklahoma.
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5 Best Photo Opportunities in Oklahoma City
by Shawn S. Lealos. Posted Sep 21st 2010 07:37 PM
Continue ReadingIt may come as a surprise to many people, but Oklahoma City is the eighth-largest city in the United States by land area, including consolidated city-counties. The borders of the city stretch out in every direction, meaning there are plenty of photo opportunities in Oklahoma City. Here are five can't miss photo opportunities in Oklahoma City.
Lee Van Grack
Happy Hour in Oklahoma City
by Kristin Packnett. Posted Sep 9th 2010 02:59 PM
Continue ReadingOklahoma City offers several choices to make your happy hour, well, happy! Here's my advice for finding the best happy hour in Oklahoma City.
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Oklahoma City with Kids: A Perfect Family Day
by Shawn S. Lealos. Posted Aug 16th 2010 01:23 PM
Continue ReadingOklahoma City is full of fun and educational destinations for parents with small children. A day's vacation can include dinosaurs, alligators, picnics, and movies -- all with a focus on enjoying Oklahoma City with kids.
Oklahoma City with Tweens: A Perfect Family Day
by Shawn S. Lealos. Posted Aug 16th 2010 09:00 AM
Continue ReadingOklahoma City's Adventure District offers the ideal spot for a family vacation with kids aged 8 to 12. Located at the crossroads of I-35 and I-44, the Adventure District offers a number of tourist attractions -- three of which are very tween friendly -- and a variety of activities sure to please everyone when you take a family vacation to Oklahoma City with tweens.
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text:
Home > Research by Institute Staff > Michigan's 1998 Elections
by Denise Roth Barber, Oct. 01, 2000
Read Now:Michigan's 1998 Elections 39 kB
Don't miss out on the latest state-level updates delivered straight to your inbox, get started with myFollowTheMoney!
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Read Now:Michigan's 1998 Elections 39 kB
Only 4 percent of ARRA contract recipients gave money to 2008 state political campaigns, but they received 14 percent of the total amount awarded in the last 6 months of 2009.


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I'm signed up for the Mountains of Misery ride next weekend. This will be my second. I made it last year up to Mountain Lake without stopping or walking (horrors!)
I am so behind in my riding, my weight, and just about everything compared to last year. I've only done 4 century rides this year, and two were flat as a pancake.
I have considered skipping the ride this year, but I've already paid, and I have $225 worth of non-refundable hotel reservations in Blacksburg. I guess that's a good thing ;) My plan is to do at least the 70 miles back to Newport, and see how I feel at that point.
Today will be my last pre-ride chance to train. I have a route mapped out that takes in part of Fauqier County, and 33 miles on Skyline Drive, about 7500 ft of climbing total. Hope the rain holds off!
Hope to see a few of you at the ride.
p.s. is it tempting fate or giving myself an "out" if I bring along cleat covers in case I have to walk the last 3 miles?


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Nas' Time Is Illmatic documentary, which was picked up by Robert De Niro's Tribeca Film company recently, has now earned a global distribution deal.
"Submarine Entertainment has closed deals at Cannes for Australia/New Zealand (Madman Entertainment), the U.K. (Dogwoof), Germany (NFP films), Italy (Feltrinelli), Japan (Parco) and Scandinavia (NonStop Entertainment)," Variety reports.
The film, which is based on Nas' debut album Illmatic, has become a hit at the Cannes Film Festival in France, according to MSN.
According to Variety, the global deal for the film was negotiated by several people.
"The deal in was negotiated by David Koh, Dan Braun and Josh Braun of Submarine on behalf of the filmmakers along with Paul Wiegard, Managing Director of Madman Entertainment; Oli Harbottle, Head of Distribution for Dogwoof; Christophe Ott, Managing Director of NFP; Anastasia Plazzotta, Managing Director of Feltrinelli Italy; Yuuki Matsuzawa, Parco Japan; and Jakob Abrahamsson, Director of Acquisitions for NonStop Entertainment," the report says.
Nas' Time Is Illmatic screening in April was attended by Robert De Niro, Wale and Raekwon, among others. When it was picked up by Tribeca, Nas released the following statement.
"I want to thank Robert De Niro, Jane Rosenthal & the Tribeca Film family for all of the love & support they've given Time Is Illmatic," Nas said. "It is an honor to be in partnership with them. I feel there is a cultural kinship bonded by the city of New York."


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Dennis McGonagle Professor of Regenerative Medicine and Consultant Rheumatologist, Academic Unit of Musculoskeletal Disease, University of Leeds and Chapel Allerton Hospital
Michael Benjamin Professor of Musculoskeletal Biology and Sports Medicine Research, School of Biosciences, Cardiff University
Issue 4 (Topical Reviews Series 6) Autumn 2009 Download pdf
'Enthesitis' is the term used to describe inflammation at tendon, ligament or joint capsule insertions. It thus applies to disease associated with the spondyloarthritides (SpA) including ankylosing spondylitis, psoriatic arthritis, reactive arthritis and undifferentiated SpA. The term 'enthesopathy', however, has a wider meaning and designates all pathological abnormalities of insertions including inflammatory changes and degenerative problems.
There are two types of enthesis: fibrous and fibrocartilaginous. At the former the fibrous tissue of the tendon or ligament extends all the way up to the bone, but at the latter there is a small plug of fibrocartilage at the attachment site itself.1 Most entheses of rheumatological significance are fibrocartilaginous. The presence of this tissue at an enthesis stiffens the tendon/ligament and thus helps to create a more gradual change in mechanical properties between soft and hard tissues. In particular, it ensures that any bending of the tendon/ligament fibres during joint movements is spread gently away from the bone – thus dissipating stress concentration. However, tissue specialisations at the enthesis itself are often only part of the adaptations evident at many attachment sites. At many locations there is a whole group of tissue modifications in the immediate vicinity which collectively constitute an 'enthesis organ' (see below). Each component plays a role in the overall task of stress dissipation.
Until the middle of the last century both rheumatoid arthritis and SpA were considered part of the same spectrum of inflammatory disorders. However, the work of Wright in Leeds and pathological studies by Bywaters and Ball, in particular, led to the eventual recognition that enthesitis was an important distinguishing feature between these two categories of disease.1 Enthesitis was eventually included in the European Spondyloarthropathy Study Group (ESSG) criteria for the classification of SpA. It was also recognised in paediatric inflammatory disease as part of the seronegative enthesopathy and arthritis (SEA) syndrome. The advent of modern imaging modalities, including ultrasound and magnetic resonance imaging (MRI), has transformed our understanding of the clinical significance of enthesitis since clinically unrecognised enthesitis is very commonly found in early SpA when these modalities are used.2 This review covers recent clinically relevant observations in relationship to the enthesis and observations for imaging and therapy that are relevant to diagnosing and treating enthesitis.
Enthesitis manifesting as pain, protracted stiffness and prominent swelling of large insertions, including those of the Achilles and patellar tendons, is characteristically seen in ankylosing spondylitis, psoriatic arthritis and reactive arthritis.3 When such lesions are associated with swelling of joints and/or other extra-articular lesions, clinical recognition of SpA is rendered fairly simple; when they occur as an isolated phenomenon and without a history of infection or psoriasis, diagnostic difficulty can arise. In such cases, patients may be referred to sports medicine or orthopaedic clinics and obtain treatment for alternative conditions such as Haglund's deformity – a mechanically-related condition of the 'enthesis organ' (see below) in the vicinity of the Achilles tendon. These scenarios are all the more likely as radiographic examination may be normal and blood inflammatory markers may not be elevated. Conversely, when imaging of isolated entheseal-based pathologies shows evidence of extensive bone oedema, unnecessary investigations, including bone biopsy, may be undertaken if the primary clinical diagnosis is not recognised.
Enthesitis most frequently presents as pain, stiffness and tenderness of insertions without much swelling. Swelling may, however, be a prominent feature at large insertions in the lower limbs. In addition to being clinically recognised at the Achilles enthesis and patellar tendon insertions, this pattern of disease is well recognised at the plantar fascia, the elbow epicondyles, other insertions about the knees, spinous processes of the vertebrae and at other sites, including the iliac crest. Generally this type of enthesitis is recognised in conjunction with other features of SpA including synovial joint swelling, dactylitis or axial disease (all of which have an entheseal-associated or entheseal-based pathology on imaging).
In the absence of joint swelling, enthesitis may thus be difficult to recognise. Although the SpA are truly inflammatory disorders, the enthesis is a relatively avascular structure and inflammatory markers, including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), may not be elevated in the presence of entheseal-related pathologies. This is best exemplified in the inflammatory back pain that accompanies ankylosing spondylitis, where undoubted inflammatory activity is not necessarily associated with elevation of inflammatory markers. Therefore it is highly likely that some cases of enthesitis-related disease are being missed, misdiagnosed and not referred to rheumatologists.
Mechanically-related tendinopathy or enthesopathy may occur from injury, including sports-related activity. Imaging studies may confirm the presence of entheseal pathology but the appearances, whether at the annulus or bone-disc interfaces in the spine or the plantar fascia, may be similar in both mechanical and inflammatory disease.4 In the case of the Achilles tendon, degenerative tendon disease typically occurs 2–6 cm proximal to the enthesis itself, whereas inflammatory disease is based around the insertion and adjacent bone.5
It may be that both inflammatory and degenerative enthesopathy share common features. Entheses are sites of high mechanical stressing and with age normal entheses are subject to wear and tear; thus degenerative changes occur at their fibrocartilages that are similar to those seen in osteoarthritic articular cartilage. Imaging of small joints in osteoarthritis and psoriatic arthritis shows that enthesis-related abnormalities are common to both conditions; changes are qualitatively similar in the two but quantitatively greater in the primary inflammatory disorders (Figure 1).6 In fact, the similarities between mechanical and inflammatory enthesitis have highlighted the possibility that site-specific biomechanical factors may lead to disease initiation in SpA. Such factors include microdamage and repair. It is little wonder that the differentiation between mechanical and inflammatory disease can sometimes be difficult.
The choice of imaging modality depends on whether the suspected enthesitis is in the axial or peripheral skeleton. If it is in the former, MRI is the modality of choice. If in the latter, and the suspected site of enthesitis is clinically accessible to an ultrasound probe, then ultrasound would be the preferred method. For some synovial joints, including the hip and knee, where the insertions (including those of the cruciate ligaments) may be inaccessible to the probe, MRI is the test of choice.
The features of enthesitis on MRI are twofold. Firstly, perientheseal osteitis at the site of attachment is seen in up to 50% of locations of enthesitis (Figure 2). The other feature is soft tissue oedema at the enthesis and the immediately adjacent area. It has not yet been established whether this osteitis is more common at certain sites and to what degree there may be differences between osteitis lesions in different types of SpA, but its severity is generally greater in HLA-B27 patients. It is important to point out that a normal MRI scan, particularly in the spine, does not exclude enthesitis. This is because (a) bone oedema may be absent in the presence of enthesitis and (b) the enthesis being a relatively avascular structure does not readily accumulate fluid, hence is not well seen on MRI. Furthermore, the spatial resolution of MRI in the spine is quite low. Therefore abnormalities may not be appreciated. This means that in patients with inflammatory back pain the possibility of SpA cannot be excluded on the basis of a normal scan or normal blood investigations. It remains to be determined whether normal MRI scans are associated with less likelihood of future spinal fusion. For the same reason, MRI of synovial joints may not show enthesitis because of an absence of bone oedema at sites of enthesitis; moreover the soft tissue inflammatory changes associated with synovitis may mask enthesitis-related changes.
The sonographic features of enthesitis include hypoechoic thickening of the tendon or ligament, erosion and spur formation and fluid with synovitis in the immediately adjacent bursa, such as the retrocalcaneal bursa associated with the Achilles tendon.7 More recently, increasing experience with power Doppler scanning has been also used to assess enthesitis, but this needs further validation. Ultrasound permits good visualisation of accessible insertions, but of course is unable to show the bone oedema changes.
What is becoming increasingly clear is that entheseal involvement may be subclinical. A significant number of patients with psoriasis, but without any musculoskeletal symptoms, have subclinical entheseal abnormalities.8 It is presently unclear whether these changes indicate true pathology or have prognostic significance.
The clinical assessment of entheseal pathology is often difficult due to lack of clinically apparent swelling of the structures and clinical inaccessibility of the site. But how do clinical enthesitis scores fare? There are several systems that have been developed for scoring enthesitis and all basically rely on applying pressure over an insertion point to elicit pain. This is taken to be indicative of enthesitis. However, such scoring systems are almost identical to those used for fibromyalgia except that the pressure is applied over different points. Clinical enthesitis scoring systems have thus far proved to be useful surrogate outcomes following anti-TNF therapy, usually showing improvement. However, they have not been assessed as diagnostic tests in early arthritis and their interpretation in osteoarthritis or fibromyalgia has not been resolved since the ultimate gold standard validation of histopathological comparison is not available owing to the difficulty of obtaining entheseal biopsies.
In rheumatoid arthritis, joint inflammation is associated with bone loss and this underpins joint damage and disability. Suppression of synovitis prevents bone damage and, ultimately, disability. Conversely, inflammation in ankylosing spondylitis is associated with new bone formation. This new bone forming between two adjoining entheses attached to adjacent vertebrae in the axial skeleton leads to spinal ankylosis which, itself, leads to disability. Thus the relationship between inflammation, new bone formation and disability in ankylosing spondylitis appears to be something of a paradox since inflammation generally has a catabolic effect on bone.
The mechanism of the bone changes at insertions is only now being studied. There is a tendency for new bone formation to occur at normal entheses with age.9 At the Achilles tendon, bony spurs usually develop at the most distal part of the insertion. In SpA, erosion formation occurs at the proximal part of the enthesis in early disease, but in late disease erosions seem to heal and large spur formation again occurs at the distal part of the attachment site. Therefore, in man, there is an anatomical, biomechanical and temporal uncoupling between the inflammatory phase of disease and new bone formation and it appears that the bone formation follows on from the inflammation and may be a distinct phase. In animal models the uncoupling between inflammation and bone formation is more pronounced but the translational relevance of this observation needs to be defined.10
All of this is extremely relevant to clinical practice, especially in terms of SpAs, since it is possible that the suppression of inflammation in ankylosing spondylitis could paradoxically lead to ongoing or even accelerated spinal fusion at the actual site of active enthesitis, something that was predicted several years ago.11 It remains a possibility that episodes of active inflammation in ankylosing spondylitis inhibit new bone formation and that the effective therapeutic suppression of this could have the unforeseen consequence of new bone formation. This awaits further longitudinal studies of moderate to long durations. In clinical practice patients being treated with anti-TNF agents do not seem to lose spinal mobility, but the currently available short-term follow-up data using radiography suggest that spinal fusion related to entheseal new bone formation may progress in ankylosing spondylitis in spite of biologic treatment.12 However, most studies of this relationship to date have been of established disease using radiography, which is a relatively insensitive measure. Studies in early disease will determine whether anti-TNF treatment can inhibit new bone formation at insertions. This is important since the prevention of entheseal new bone formation in episodes of inflammatory enthesitis will likely prevent the sequelae.
Given that biomechanical factors are likely to play a role in inflammatory enthesitis, reduction of biomechanical stresses by such means as insoles and cushioning should be used where appropriate. Local corticosteroid injections often help if anti-inflammatory agents fail to alleviate pain associated with isolated enthesitis. However, for isolated severe enthesitis with soft tissue swelling, anti-TNF agents have been shown to be effective in case series and in the experience of one of the authors (D McGonagle). However, use of biologic therapies within the UK health service and elsewhere is restricted and there are currently no specific guidelines for the use of these agents for isolated enthesitis. Expert opinion would suggest that the agents should be used if all else fails, as isolated enthesitis can be very debilitating, particularly in the lower limbs. Moreover, since enthesitis is usually self-limiting the problem may eventually settle, so patients may not be committed to indefinite therapy. In the past local radiotherapy has been used with some success, especially with disabling heel enthesitis.13 Since this can be administered safely as a single dose, bearing in mind the potential side-effects of anti-TNF agents local radiotherapy should still be considered.
Quite often, treatment of enthesitis is simply part of the treatment of an associated polyarthritis where agents including sulfasalazine and methotrexate are used. Robust evidence for the efficacy of these agents in early SpA is lacking. Where mild to moderate enthesitis is recognised in association with more generalised inflammation for which anti-TNF agents are being used, then clinical enthesitis scores and MRI and ultrasound scores all improve.
Enthesitis has historically been considered as a disorder of a focal attachment site; however, entheses together with adjacent tissues may form mini organs, dubbed 'enthesis organs'.14 This ensures that the stress dissipation at attachment sites is distributed over a wide area. Perhaps for this reason, the pain with tennis elbow may sometimes be diffuse rather than focally located at the common extensor origin. Rheumatologists need to appreciate that enthesitis-associated pain may be over a greater territory than the insertions themselves. This likely applies to the Achilles tendon enthesis and the retrocalcaneal bursa, as enthesis-related cartilages actually form the walls of the bursa itself. This explains why bursitis may be a prominent feature of Achilles enthesitis.
The enthesis organ concept is shown in Figure 3. It seems likely that the two complementary fibrocartilages adjacent to the enthesis itself derive their nourishment and lubrication from the adjacent synovium. This is identical to the relationship between synovium and articular cartilage. This means that pathology related to the enthesis could trigger synovitis. Indeed, normal entheses are riddled with microdamage in aged subjects; this can be associated with microscopic synovitis, including villus formation and microscopic inflammatory cell infiltration in the immediately adjacent synovium, which is conceptualised in relationship to a synovio-entheseal complex.
There is a close anatomical integration between the enthesis and synovium which has recently being termed a 'synovio-entheseal complex'.15 According to this scenario the enthesis fibrocartilages that occupy a location adjacent to synovium (in joint or bursae or tendons) are dependent on the synovium for lubrication, oxygenation and removal of microdebris. The enthesis insertion being itself fibrocartilagenous is avascular. Therefore derangements in the enthesis would be expected to trigger an inflammatory response in the adjacent vascular synovium.
These micro-anatomical considerations may be vital for understanding the importance of the enthesis in synovial joint disease in general. While the role of the enthesis is fully appreciated in SpA, these recent findings point towards novel mechanisms of synovitis and joint damage in osteoarthritis that have previously been unappreciated.16,17 Normal enthesis fibrocartilage shows age-related changes typical of osteoarthritis, including fissuring, fibrillation and degeneration. It is probably best to use the term 'enthesopathy' to describe the changes in osteoarthritis since these appear to be generally less inflammatory, but it must be pointed out that there are no comparative histological studies to date. Also the role of the enthesis organ in bone erosion formation in rheumatoid arthritis has recently been described.18 Specifically, early rheumatoid arthritis erosion formation occurs immediately adjacent to the small joint collateral ligament insertions as a result of enthesis-associated compression of bone at these sites.18
From being a 'second-class citizen' in SpA, the enthesis is now centre stage as a structure responsible for disease in this category of abnormalities. The recognition of the importance of the enthesis has important implications for an improved immunopathological understanding of SpA.19 The role of the enthesis in other types of arthropathy including osteoarthritis and even in the patterns of joint destruction in rheumatoid arthritis has only recently become appreciated. Although tissue from the enthesis is inaccessible compared to the synovium, it holds great potential for a future better understanding of inflammatory and degenerative disease.20 Much more work needs to be done pertaining to the clinical evaluation of entheseal-related pathology.
Browse previous issues of Topical Reviews (all issues available as downloadable PDFs)


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Things to see and do - Betanzos
Leaving for Spain
Church of Santa María del Azogue :
Nearby tourist sites
Nearby hotels
Hotel Palacete Betanzos from44 €Book
Hotel Garelos from55 €Book
Church of Santa María del Azogue
Church of Santa María del Azogue : Michelin's recommendations
Dates back to the 14C and 15C. The façade is graciously asymmetrical, with an advanced central section with a rose window and portal with jagged archivolt. On either side of the door stand two niches containing statues of the Virgin Mary and the Archangel Gabriel, symbols of the Annunciation. Three naves of equal height and a single frame make up the spacious interior.


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La Caravella Restaurant
La Caravella Restaurant in Venice
La Caravella, is a typical and traditional restaurant andis among the best Venice restaurants, located close to the St. Mark square, in via XXII Marzo street, one of the most important of the city.
Open since early 60's, it distinguishes since those years for its cuisine, unique ambience (reminds the famous boat) and very warm and professional welcome. This tradition has been guaranteed thanks to the constant presence of the Serandrei family.
La Caravella restaurant has traditional dishes, infact its offer is related to the historical culinary Venetian tradition, however, dishes follow seasonality of products to respond at lighter needs of a modern life style.
Venice restaurant La Caravella has the following operating hours:
Open everyday and all year round
12:00 a.m. – 03:00 p.m.
07:00 p.m. – 11:00 p.m.
From May to September, meals are served in the typical Venetian courtyard, where the wells, tranquillity and elegance, make a perfect setting for an unforgettable culinary experience.
Restaurant La Caravella Venice,
viaXXII marzo 2398
tel.: +39.041.5208901
fax.: +39.041.5207131 – 041.5205858
e-mail email@example.com


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Assistant Professor of Management Presents on 'Transformative Cooperation' at Florida Conference
University of La Verne Assistant Professor of Management Dr. Loren Dyck has examined the sacrifices made by people in a long-term conflict and presented his findings at a conference in Florida August 13, 2013.
His paper titled, "Transformative Cooperation at Honokahua: Learning from the Past to Build Virtuous Human Systems" was presented at the Academy of Management Annual Meeting in the Social Issues in Management Division in Lake Buena Vista in Orlando. It examined the sacrifices and learning that occured between parties in a long-term conflict as a means to theorize about the process of cooperation and the "factors that make it transformative for all parties involved in the dispute."
Dyck reviewed cooperation, intractable conflict and transformative cooperation. He then explained his study methods that occurred at the Honokahua Burial Site on Maui in Hawaii.
"Telling of the story at Honokahua is next followed by my analysis that leads to conceptual categories and theorizing about transformative cooperation," Dyck said. "I then discuss the findings and offer implications for ethical organizing and building virtuous human systems."


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Legendary Elkhart musical instrument manufacturer dies
ELKHART — Music was in Daniel Henkin's heart from the first time he picked up a clarinet at 6 years old until he died at 82.
Henkin, who revived the musical instrument industry in Elkhart, died Thursday evening, leaving a legacy of creativity and love for music among friends and family.
"He was an imaginative person," said Hisako "Mary" Henkin, his wife of 55 years. "He could create things from nothing. Just every day, he was making something, making music, writing. He loved life. He was a very, very good man — a very smart guy. Everybody said he was a genius."
Henkin's passion for music blossomed in 1945 at the ripe age of 15 when he joined the Kansas City Philharmonic, becoming the youngest clarinet player in a major U.S. symphony. After World War II, he was the band director for the U.S. Army Air Forces in Hawaii.
In 1969, Henkin started working as advertising manager at C.G. Conn, a large band instrument producer in Elkhart. He left the company to purchase K.G. Gemeinhardt, a company that made flutes in Elkhart. That was his first venture into the musical instrument business but not his last.
"At the time, C.G. Conn had gradually left Elkhart," said Robert Smith, a close friend and neighbor of Henkin. "They relocated one plant here and another plant there."
Elkhart had been known as the "band instrument capital of the world" and was in danger of losing that title, Smith said. Henkin saw this happening and bought C.G. Conn with the intention of moving its headquarters back to Elkhart, and in 1981, he did just that. Henkin bought the company and more than a dozen other instrument manufacturers.
"In the history of the musical instrument business, he's a major figure as far as how he structured his businesses, the way they changed, the way they sold to people, the way they set up and educated kids and started band programs around the United States in support of him." said Chris Blackwood, a family friend whose father worked with Henkin.
To mark C.G. Conn's homecoming, Henkin hosted a weeklong celebration that featured elaborate parties and special musical guests, including personal friend Doc Severinsen, a jazz trumpeter known for leading the band on "The Tonight Show with Johnny Carson."
Henkin enjoyed entertaining friends, especially with live music. Tony Biggs, a former Elkhart Truth publisher, was lucky enough to attend many of the gatherings that Henkin hosted. Biggs met Henkin shortly after moving to Elkhart and they became fast friends. Biggs said Henkin could talk for hours on end about the arts, especially big band jazz.
"You could hold a discussion with Danny on any subject, and it would be a lot of fun," said Biggs, who now lives in New Mexico but has kept in touch with Henkin since moving to the Southwest.
Blackwood described Henkin as a "legendary character in Elkhart." Henkin was honored in 2005 when he was inducted into the Elkhart Musical Instrument Manufacturers Historical Museum Hall of Fame.
"Danny was a dreamer," he explained. "He had no fear of trying new things, and he didn't really care what other people thought about it. He just wanted to do what made him happy. He's a larger than life person. Everybody I know has a Danny story."


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Squier Fat Tele Bridge Pickup
Sku #300149000000000
Telecaster Pickups (Single Coil)
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Comments about Squier Fat Tele Bridge Pickup:
I have no idea what's "fat" about this pickup. It's just a basic Telecaster bridge position pickup. My example has a DC resistance of about 3.9K. I haven't used it yet but this suggests it will have a rather high resonant peak and not particularly strong output. There's lots of space on the bobbin to wind on more turns and do a tapping option. It comes with no packaging at all. Mine arrived with one lead damaged; it will be easier to repair than send back. The pole pieces extend through a steel base and contact two (ceramic?) bar magnets. No mounting hardware included. Looks to be wax potted, done cleanly. Usable, appropriately priced.