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In every area of practice, WilmerHale brings the insight, dedication to excellence, and commitment to client service needed for our clients to achieve their business objectives. Our five-department structure and team approach to service enable us to provide the highest level of responsiveness and access to lawyers with the most appropriate experience.
The New York State Bar honored WilmerHale with its 2014 Empire State Counsel recognition for generous pro bono contributions. Learn more.
WilmerHale's exceptional depth and breadth of experience in corporate law, combined with our ability to draw on the firm's other market-leading practices, enables us to provide a one-stop solution to corporate clients at all stages of growth. Leveraging our experience in the areas of emerging companies, venture capital, public offerings, mergers and acquisitions, public company counseling and strategic alliances, we help our clients achieve strategic advantage, navigate complex legal and business issues, and realize their long-term business objectives. We represent public and private companies, investment banks, venture capital and growth equity firms, and individual entrepreneurs. We are widely recognized for our representation of technology, life sciences, financial services, defense and other regulated industry clients.
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Our lawyers are highly skilled at counseling companies on a variety of complex business transactions and legal issues. Specific areas of focus include:
Emerging Company and Venture Capital: Startup companies and investors rely on us to take their ventures from founding to funding to market leadership and successful IPO or sale. We regularly counsel emerging companies, entrepreneurs and investors on seed, venture capital, growth equity, venture debt and strategic financings. Our extensive experience advising emerging companies enables us to efficiently manage seed and venture capital financings and provide strategic value. We have handled more than 2,750 venture financings raising approximately $30 billion since 2004. In 2014 alone, we served as counsel in more than 300 venture financings raising in excess of $8 billion (learn more).
Our recent experience includes:
Capital Markets Transactions: We represent both issuers and investment banking firms in initial public offerings, follow-on public offerings, PIPE placements, cross-border offerings, Rule 144A transactions, and other private placements and tender offers. Our experience ranges from IPOs by emerging companies to private offerings of sophisticated debt instruments by established public companies. In 2014, we advised leading companies in life sciences, technology, financial services, communications and other industries on more than 50 public offerings and Rule 144A placements raising approximately $13 billion. Since 2004, we have served as counsel in nearly 500 public offerings and Rule 144A placements raising more than $150 billion (learn more).
Mergers and Acquisitions: Our mergers and acquisitions experience ranges from counseling clients on public-public M&A transactions and related disclosure and fiduciary duty issues to the unique issues presented by acquisitions of venture-backed and private equity-backed companies. We also advise clients regarding hostile transactions and activist investors and represent investment banks serving as financial advisors in M&A transactions. In 2014, we advised clients in M&A transactions with an aggregate value in excess of $50 billion, providing guidance in areas including corporate, securities, antitrust, intellectual property and tax. Since 2004, we have participated in more than 1,000 mergers and acquisitions with a total value in excess of $400 billion, ranging from sales of VC-backed companies to multibillion-dollar global mergers (learn more).
Representative experience includes:
Public Company Counseling: With a team that includes former SEC senior staff members—among them the most recent Director of the SEC's Division of Corporation Finance—we offer a compelling combination of substantive knowledge and practical experience. Drawing on insights developed by serving as outside counsel to hundreds of US and non-US public companies, we provide timely, tailored and practical disclosure, compliance and corporate governance advice across industries. We advise on emerging governance and disclosure issues, SEC and stock exchange requirements, shareholder proposals, corporate governance policies, anti-takeover defenses and emerging best practices. In addition, we address interactions with activist shareholders, and handle matters involving the Sarbanes-Oxley Act, Dodd-Frank Act and JOBS Act. We routinely draft and review periodic reports, proxy statements and other documents filed with the SEC, as well as press releases and informal market communications, and assist clients in responding to SEC staff comment letters. We have extensive experience advising on compliance with Regulation FD, Regulation G, Schedule 13D/13G and Section 16 reporting requirements, and executive compensation disclosure. We have advised numerous boards and management teams on key governance issues, and serve as independent counsel to a number of audit committees.
Strategic Alliances, Joint Ventures and Licensing Transactions: Our lawyers—many of whom have backgrounds in computer engineering, biochemistry and other technical fields—negotiate agreements for clients across a broad spectrum of industries. We handle a high volume of complex joint ventures, strategic alliances, outsourcing, partnering and licensing transactions each year, many of which span international borders (learn more). Our recent experience includes:
Our clients, which span diverse industries, include:
October 6, 2015
WilmerHale Reps Skyworks in $2 Billion Acquisition of PMC-Sierra
Skyworks Solutions, Inc. and PMC-Sierra, Inc. (PMC) announced a definitive agreement under which Skyworks will acquire PMC for $10.50 per share in an all-cash transaction valued at approximately $2 billion.
September 18, 2015
Wilmer Cutler Pickering Hale and Dorr LLP Named a Top-Tier Firm by The Legal 500 UK
In the 2015 edition of The Legal 500 UK, WilmerHale is named a top-tier firm for dispute resolution - international arbitration and crime, fraud and licensing - fraud: white-collar crime, and is recommended in six other practice areas.
September 14, 2015
LMG Life Sciences Release 2015 Rankings, Again Names WilmerHale a "Life Cycle Firm"
In its latest edition, LMG Life Sciences recognizes eight WilmerHale practice areas and 16 attorneys, and for the fourth consecutive year names WilmerHale a "Life Cycle Firm."
August 31, 2015
The Best Times To Get A Grip On Your Startup's IP
An article by Partners Gary Schall and John Hobgood, posted on TechCrunch on August 31, 2015.
August 28, 2015
How Misunderstanding a Startup's 'Valuation Cap' Can Get Expensive
John Demeter, WilmerHale counsel and a Wall Street Journal expert panelist, discusses the importance of understanding valuation caps in this article published by The Experts blog on WSJ.com, August 28, 2015.
August 17, 2015
WilmerHale Lawyers Named Among the 2016 Best Lawyers in America®, Seven Recognized as Lawyers of the Year
Best Lawyers in America® recognizes 99 WilmerHale lawyers and names seven partners as Lawyers of the Year in its 22nd edition. Only one lawyer in each legal practice specialty within each region is honored as a Lawyer of the Year.
July 16, 2015
USCIS Clarifies Position on Worksite Changes and Need to File Amended H-1B Petitions
The United States Citizenship and Immigration Services (USCIS) recently issued guidance on changes in H-1B (visa) work locations in the wake of the Administrative Appeals Office's (AAO) April 9, 2015 decision in Matter of Simeio Solutions LLC.
July 15, 2015
SEC Proposes Compensation Clawback Rules
On July 1, 2015, the Securities and Exchange Commission voted 3-2 to propose new rules requiring national securities exchanges to establish listing standards requiring listed companies to develop, implement and disclose clawback policies.
July 2, 2015
WilmerHale Lawyers Named to Best Lawyers in Germany 2015
Nine WilmerHale lawyers from the Berlin and Frankfurt offices were listed in Best Lawyers in Germany, ranking in a recent edition of Handelsblatt.
July 1, 2015
WilmerHale Named a Leading National Firm in the United States by The Legal 500
The Legal 500 United States has released its annual rankings, selecting WilmerHale as one of the preeminent law firms in the country.
February 10, 2016
Practising Law Institute: Corporate Governance – A Master Class 2016
New York, New York
December 7-8, 2015
Practising Law Institute: Annual Disclosure Documents 2015
November 19, 2015
MCLE: Commercial Real Estate
Boston, Massachusetts
November 3, 2015
MCLE: Corporate Practice
October 28-30, 2015
Practising Law Institute: 47th Annual Securities Regulation Institute
October 29, 2015
Executive Compensation & Team Composition: Attracting and Retaining the Best and Brightest to Your Team
October 27, 2015
Tackling Your 2016 Compensation Disclosures: The Proxy Disclosure Conference
San Diego, California
October 20, 2015
2015 Proxy Season Review and Outlook for 2016 Proxy Season
Boston Bar Association: Second Annual Mergers & Acquisitions Conference
October 16, 2015
Society of Corporate Secretaries & Governance Professionals: Eastern New England Chapter Meeting
Wellesley, Massachusetts
WilmerHale's annual IPO, Venture Capital and M&A Reports offer insights into market conditions and provide comprehensive statistics and analysis that are hard to find elsewhere.
Our 2015 IPO Report offers a detailed analysis of, and outlook for, the IPO market. The report features regional breakdowns, useful IPO market metrics, an update on the rates of adoption of various elements of JOBS Act relief available to emerging growth companies, and helpful tips on how to keep your directed share program company-friendly. We examine the pros and cons of employee stock purchase plans; review various SEC, stock exchange and other considerations around director independence; address key areas of regulatory diligence for companies going public; and offer a helpful walk-through of the process of SEC review of Form S-1 registration statements in the lead-up to an IPO.
The 2015 Venture Capital Report offers an in-depth analysis of, and outlook for, the US and European venture capital markets. The report features industry and regional breakdowns; an analysis of trends in venture capital financing, convertible debt and VC-backed company M&A deal terms; and a look at important considerations for startup founders weighing the costs, benefits and optimal timing for company incorporation.
Our 2015 M&A Report contains a detailed review of, and outlook for, the global M&A market. Other highlights include a comparison of deal terms in public and private acquisitions, updates on takeover defenses and the current climate around proxy access, and a look at the use of social media by public companies and activist shareholders in contested situations. We also examine recent trends in merger control, discuss lessons from Cigna v. Audax for sales of VC-backed companies structured as mergers, address the challenges posed by pre-IPO acquisitions, and survey key terms in sales of VC-backed companies.
Each report also includes a center spread showcasing prominent recent transactions in each area and company counsel rankings from independent sources showing WilmerHale's preeminence as counsel in IPOs, VC financings and sales of VC-backed companies.
To request a hard copy of any of the reports, contact the WilmerHale Client Development Department at firstname.lastname@example.com or call +1 617 526 5600.
Congress Passes New Capital Formation Legislation
Dodd-Frank Whistleblower Working Group
Initial Public Offerings: A Practical Guide to Going Public - WilmerHale's acclaimed IPO guidebook
UK Bribery Act 2010
In every area of practice, WilmerHale brings the insight, dedication to excellence, and commitment to client service needed for our clients to achieve their business objectives. Our five-department structure and team approach to service enable us to provide the highest level of responsiveness and access to lawyers with the most appropriate experience.
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The Icicle Works
The Icicle Works were an alternative rock band which formed in Liverpool, England in 1980. The band's original lineup consisted of Ian McNabb (vocals, guitar), Chris Layhe (bass, percussion) and Chris Sharrock (drums). Layhe and Sharrock left the band in 1988, but McNabb continued the band with replacement members until 1990. McNabb reformed the band with different replacement members in 2006, but this incarnation lasted only until 2008. Sharrock, who remains on good terms with McNabb, later drummed for The La's, World Party and Oasis.
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subset: commoncrawl


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By: koivo
Test and drive Xpand Rally Xtreme
Views: 1,072 | Posted: 05/25/2011
By: PolicenautsScott
Trailer of Xpand Rally Xtreme.
Views: 1,766 | Posted: 05/25/2011
By: pozmu
Some talk from developer and some gameplay footage. Enjoy!
Views: 923 | Posted: 05/11/2010
Hug the turns and fling yourself past the opposition in off-road racing mayhem.
Views: 28,282 | Posted: 11/09/2006
The game that dares to ask the question, "What is Xtreme?"
Views: 15,355 | Posted: 08/21/2006


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Download of apbs-1.2.1b-mac-univ.tar.gz (45,165,632 bytes/MD5: 25565413b74195e084d12bc618ed259d) should begin shortly. If not so, try to click apbs-1.2.1b-mac-univ.tar.gz ( extenal link: SourceForge.net).
Your rating for APBS
Project DescriptionAPBS is a software package for the numerical solution of the Poisson-Boltzmann equation, a popular continuum model for describing electrostatic interactions between molecular solutes over a wide range of length scales. <http://www.poissonboltzmann.org/>. Please register at http://goo.gl/LGVU5j before downloading!


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Next Classes begin Monday, October 26, 2015. For more information call 754-321-5700 or click here to request information.
Applications are accepted on a nondiscriminatory basis from anyone having the interest, ability, and desire to benefit from an occupational training program.
MTC admits those students who:
-have completed their secondary school education
-are past the minimum compulsory education age
-are high school students (through their high school guidance department)
-Pursuant to Florida Statute 295.125.(2), veterans are given preference within the enrollment process
Basic Skills Requirements
The Florida Legislature has mandated that each adult student enrolled in a certificate/diploma program must meet minimum basic skills levels in reading, mathematics, and language arts in order to receive a Certificate of Completion or an Applied Technology Diploma.
Students not meeting the basic skills requirements will have the opportunity to receive appropriate instruction in order to achieve the required levels prior to completion of their programs.
Disabled Students
As an Equal Access/Equal Opportunity institution, students with disabilities will have equal access to all programs, activities and services, as described in Section 504 of the Rehabilitation Act of 1973 and in compliance with the Americans with Disabilities Act (ADA).
Method of Payment
Registration fees and tuition fees may be paid by credit card, debit card (only with Visa or MCC logo), or cash. We also accept Florida Prepaid College Plans and Bright Futures Scholarships.
Refund Policy
No refund can be made without the official receipt given at registration.
School Board Policy 6607 governs the refund of program fees.
There is no refund of the registration fee.
Supply, insurance and tuition fees are refundable only during the first week of classes.
If a class is canceled, a full refund of all fees, including registration, will be issued.
All refunds must be requested in person.
Supplies purchased can be paid by credit card, debit card (only with Visa or MCC logo), or cash.


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Roberts Marketing Group is focused on helping you achieve high-impact results through innovative, well-executed marketing strategies. We offer you over 20 years of Technology Marketing and Sales Management expertise, garnered from IT leaders including HP, IBM, and AT&T. Roberts Marketing Group (RMG) specializes in the following marketing disciplines:
"Janice Roberts is a highly skilled marketer, very dependable and able to quickly grasp and work with new technologies. I have collaborated with janice on numerous projects, both strategic and tactical, and consistently she has delivered excellent results."


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Alex T (RAFMA)
I've had a go at most types of climbing and enjoyed them all. Climbing has taken me some amazing places.
As an Engineer in the Royal Air Force, I'm extremely lucky to have an employer that supports my amateur climbing ambitions through a variety of means. As an additional duty to my day job, I am the RAF Climbing Team Manager. As part of the RAF Mountaineering Association (RAFMA), the team supports the best RAF climbers and competes in indoor climbing competitions.
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A 13 year-old female illustrates the problems with not being yourself, and peer pressure.
November 2000 - December 2012
- The number of young people who received services from the Restorative Justice Services Programs: 2,266
- Male: 1,227
- Female: 1039
- Young people served by The RESTORE program: 1,366
- Young people served by the Restorative Justice Conferencing Program (RJCP): 850
- Young people served using other restorative processes: 50
Young people who come through Restorative Justice are checked for later violations of the law. This is called the recidivism rate, the percentage who commit another offense.
The following recidivism rates are based on young people who entered the RJS programs from February 2008 - April 2011 and completed the program. Checks at 12 months past program completion were done for all these young participants. The recidivism checks were done on the Fort Collins Police Services Tiberon system, which covers Larimer County.
Recidivism Rate at 12 months past program completion: 8.7%
This check includes all offenses, including drug and alcohol, but not smoking violations.
Recidivism Rate at 12 months past program completion for a same or similar crime: 2%
This check includes offenses that are the same type of offense, or a similar offense to the offense for which they came to RJS. For example a shoplifting theft would be same or similar to any other kind of theft, including fraud or larceny but a theft would not be the same or similar to a drug or alcohol violation.


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Bidens Host Wounded Warriors For Early Thanksgiving Dinner
Vice President Joseph Biden and his wife Jill Biden host Wounded... News PhotoAdult,Government,Horizontal,Jill Biden,Joseph Biden,Morning,Politics,Residential Building,Thanksgiving,USA,Vice President,Waist Up,Washington DC,Wife,WomenPhotographer Alex WongCollection: Getty Images News 2012 Getty ImagesWASHINGTON, DC - NOVEMBER 19: U.S. Vice President Joseph Biden (L) and his wife Jill Biden (R) host Wounded Warriors for an early Thanksgiving Dinner November 19, 2012 at the Vice President's residence at the Naval Observatory in Washington, DC. The Bidens continued their tradition to host the 4th annual dinner for Wounded Warriors being treated at the Walter Reed National Military Medical Center and their families who will not be able to leave the DC area to be with family for the holiday. (Photo by Alex Wong/Getty Images)


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Make sure your HVAC runs smoothly this season with this deal from Geiler Home Services, a family-owned local business since 1885. They'll travel within 25 miles of Cincy to insure your home is in tip-top shape:
• $35 ($159 value) for a heating or air conditioning tune-up
• $58 ($155 value) for a single fixture drain clearing
• All technicians are factory-trained, nationally certified, and state-licensed
Geiler Home Services's Website
PAID VALUE EXPIRES ON October 9, 2020
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The incidence of single nucleotide polymorphisms (SNPs) variations of a single "letter" on specific points of the gene has been studied in all the cases. Within the family of metabolic genes the SNPs of the genes ADH1A-ADH1B-ADH1C, ADH4, ADH6, ALDH2 and CYP2E1 have been analysed; "70 % of the alcohol is broken down by enzymes encoded by these genes" points out Celorrio. Of the genes in the dopaminergic system, the SNPs analysed correspond to the genes TH, SLC18A2, DRD1, DRD2, DRD3, MAOA and COMT, "being the ones linked to the entire useful life of the dopamine: its production, delivery, action in the presence of receptors and destruction," adds the author. The incidence of the two families of genes has been analysed in two groups of population samples: 1-excessive consumers and 2-patients with dependence.
Among the excessive consumers, polymorphisms that significantly increase the risk associated with the hazardous intake of this substance were found in the ADH1B and DRD2 genes for both sexes and in the MAOA gene in women only. The analysis of the environmental variables together with the hazardous intake of alcohol displayed a high-risk profile: men, smokers, heavy consumers of meat and low consumers of fruit and vegetables, with occupations not requiring a high level of qualifications and physically not very active.
On the other hand, a significant association of alcohol dependence with polymorphisms in genes of the metabolism and dopaminergic route was observed with an SNP of the ADH1B gene in both sexes and with SNPs of TH, COMT, DRD2 in men only, whereas the association with DRD3 occurred in women alone.
The study of excessive consumers was carried out on a sample of 1,533 individuals (653 cases and 880 controls) originating in the EPIC (European Prospective Investigation into Cancer and Nutrition) project, of wh
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