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New deal makes Toronto police highest paid in country
A tentative agreement reached this week makes Toronto police officers the best paid in Canada, with a total 11.5 per cent increase over four years.
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Toronto police officers will become the highest paid in the country with a deal that provides salary increases totalling 11.5 per cent over the next four years.
A tentative agreement reached earlier this week provides a 3.19 per cent increase this year, almost 3 per cent in each of the next two years, and 2 per cent in 2014. An initial pay hike of 2.75 per cent is retroactive to Jan. 1 and will be followed by another 0.44 per cent in October.
Details of the collective agreement were presented to members of the Toronto Police Association Wednesday night. The union, representing almost 5,600 officers and 2,100 civilian members, has recommended acceptance.
It is believed to be the first time the association has negotiated a four-year contract. The term was extended from the usual three years in order to get a better overall package, the union explained in a 28-page ratification booklet handed out at the meeting.
Union members will vote on the agreement by mail-in ballot due May 25.
"I like it," a 30-year veteran of the police service said after the meeting. "In this economic climate, how can you not?"
A first-class constable earning $81,249 in 2010 will make $90,623 in 2014 if the agreement is ratified.
Councillor Pam McConnell, former police services board vice-chair, called the settlement "a bit rich," given the state of the economy. But she noted the financial benefits of a quick settlement, saying "quite an amount of money (will be) saved by that, and goodwill across the table is unmeasurable."
The deal also includes improved vacations and increases in benefits such as vision care and massage therapy. In what the union calls "the first improvement . . . in a long time," extra vacation weeks will be granted earlier in a long-serving police officer's career.
The last police contract expired Dec. 31. Negotiations between the union and the Toronto Police Services Board began in January.
The net $905.9 million police operating budget is the largest single item on the city budget. Salaries, benefits and overtime account for nearly 90 per cent of it.
The police service was under pressure from the Ford administration to cut costs along with every other city agency.
"We knew that this was going to be a difficult round of bargaining," the union said in its ratification package. "We believe we are in a position to recommend that you accept this contract as being fair and reasonable."
The last time the police contract was negotiated, in 2008, an arbitrator was appointed by the province after talks broke down. After a 13-month battle, the arbitrator hashed out a deal that increased salaries by 10 per cent over three years.
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Ordinance to remove term limits on Sebastian boards passes 1st vote
SEBASTIAN — Members of city boards in Sebastian might get to serve longer if the ordinance passed at Wednesday's City Council meeting makes it through a second vote on Nov. 16.
On the first reading, the measure to eliminate provisions in the city code that limit terms for board members to two consecutive terms or six years passed by a vote of 3-2. Council members Andrea Coy and Eugene Wolff voted no on the measure.
Wolff said eliminating term limits for boards is a two-edged sword. With term limits, the board may lose the experience of someone who has served for several years. However, it does encourage the appointment of new people to city government.
When the issue is reconsidered Nov. 16, it will be a new City Council that takes up the matter, because Wolff is not seeking re-election. A public hearing will take place prior to the second vote.
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© Jemella LTD
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OLATHE, Kan., Jan. 15 /PRNewswire-USNewswire/ -- The Kansas Bioscience Authority has launched a $2.5 million initiative to bring together researchers nationwide to create products that protect Americans from the intentional use of animal-borne diseases to disrupt the national economy or to infect humans.
The goals of the new Collaborative Biosecurity Research Initiative (CBRI) are to support interinstitutional research to: (1) develop countermeasures for foreign-animal diseases; (2) provide advanced test and evaluation capability for threat detection, vulnerability, and countermeasure assessment for animal and zoonotic diseases; (3) support licensure of vaccine countermeasures through essential animal-model testing and evaluation; and (4) strengthen biosecurity capabilities of institutions serving certain regions and populations, such as students underrepresented in biosecurity research.
Agricultural and food infrastructure is a key component of U.S. economic productivity and growth, accounting for 12 percent of the nation's gross domestic product ($1.24 trillion) and representing one in six jobs in direct or related employment.
KBA president Tom Thornton said a deliberate assault, such as a terrorist attack, or a natural outbreak, could damage the public trust in agricultural safety and the national ability to provide food and other agricultural products.
"We're issuing a call today for the nation's brightest researchers to partner with us to protect public health and safeguard the agriculture economy," Thornton said. "Our facilities are highly specialized and world-class, and our scientists are doing world-class research. Now is the time for collaboration to take on this important national challenge."
The CBRI will introduce the unique biosecurity research capabilities
and facilities at Kansas State University to investigators nationally and
develop strategic alliances to promptly confront animal and public healt
|SOURCE Kansas State University
Copyright©2008 PR Newswire.
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Resolution: standard / high
Figure 1.
ClustalW alignment of the seven KPNA proteins that comprise the importin α family in humans. Positions of the armadillo repeats (ARM 1-10) and the importin β binding (IBB) domain are indicated with colored boxes. Amino acids which are identical in ≥ 4 of the KPNA proteins are boxed.
Kelley et al. BMC Cell Biology 2010 11:63 doi:10.1186/1471-2121-11-63


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The best way to tell your kids to be active and eat healthy is to do it yourself and let them watch.
Want your children to grow up to be healthy and happy adults? Show them how much fun active living can be while they're young. Here's how.
Breathing is so simple, that kids get it. here they are explaining it to us, the adults, as if we were kids, how to do it.
Reducing childhood obesity and empowering kids to develop lifelong, healthy habits.
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Joe Chamberlain
1 portrait on display at Bodelwyddan Castle
© National Portrait Gallery, London
Joe Chamberlain
by John Singer Sargent
oil on canvas, 1896
65 in. x 37 1/4 in. (1651 mm x 946 mm)
Bequeathed by the sitter's widow, Mrs Mary Endicott Carnegie, 1957
Primary Collection
Click on the links below to find out more:
Sitterback to top
- Joseph ('Joe') Chamberlain (1836-1914), Industrialist and politician; MP for Birmingham. Sitter associated with 101 portraits.
Artistback to top
- John Singer Sargent (1856-1925), Portrait and landscape painter and muralist. Artist associated with 72 portraits, Sitter in 4 portraits.
Linked publicationsback to top
- Piper, David, The English Face, 1992, p. 239
- Ribeiro, Aileen, The Gallery of Fashion, 2000, p. 192
- Saywell, David; Simon, Jacob, Complete Illustrated Catalogue, 2004, p. 112
Subjects & Themesback to top
Tell us moreback to top
Can you tell us more about this portrait? Spotted an error, something missing, or do you know anything that we don't know? If you have any information to share please complete the form below
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On display at Bodelwyddan Castle
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Should I worry if my toddler doesn't talk much?
My toddler babbles a lot but he only says a few understandable words and not very often. The pediatrician says he's doing fine and that all kids develop at different rates, but I know he's not talking as much as other kids his age. I'd love to hear from parents of reluctant talkers on what they do to encourage their children, when their kids finally did start talking, and any other advice to help me cope.
Posted: 02/25/2003 by a BabyCenter Member
Mom Answers
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I am going through the same exact problem with my toddler not talking much. I cope with believing that every child is different and she will by 3 years of age. I know she understands directions and such. I just try to stay positive.posted 05/08/2013 by PrettyMommy101
Enjoy it. My daughter didn't say much, about 10 words until until 2 and a half. Doc gave me a brochure for intervention. Right after her 3rd Bday, she just started picking up phrases. At 38 months she's making complicated sentences and conjugated almost perfectly. My advice, wait til 3 and just pay attention to progress in terms of understanding. If they're learning, I would enjoy it. I swear, sometimes I have to ask her for a moment of silence.posted 05/05/2013 by a BabyCenter Member
My soon just turned 2. He's so smart, understands what I tell him, can find objects and what not. He communicates well, just not with words often. He says dada, mama, dog, kitty, uhoh, hi, hello.. He tries with a lot of b words and said snow a few times.. But i think he just doesn't feel the need to talk since he communicates with other sounds and gestures well enough. Meanwhile my husband is worried because he was speaking sentences at this age.. And our son Has had a few bumps to the head. It's nice to know other moms are in the same boat. I'm sure your little man will talk when he feels he needs to too.posted 03/30/2013 by rachelgood_00
(continued) Fast-forward to 24 months, still babbling. Same response. Fast forward another 12 months, 3 years old and my son spoke about 10 words. Still nothing, speech therapy to help him. Tubes for his hearing, etc. Fast-forward 6 years later, 7 years old. Through the suggestion of my son's teacher we had him diagnosed. Results, my son is on the autism spectrum with a form referred to as PDD Pervasive Developmental Disorder. Had I trusted my instincts and got a second opinion or pressed for other forms of testing rather than the standard issue responses, we could have caught this early, made steps to treat it and he would have been better off. My youngest son is now 18 months old, babbling, very active and whenever I hear, he will get there...I worry. I am gauging how my son reacts. I am looking to see that he engages with others. If your child is hyper focused and ends up being upset when you disrupt his pattern, dig deeper than the standard answers.posted 02/06/2013 by a BabyCenter Member
It is true that you should trust your and your child's instincts. But I would not dismiss your instincts over a doctor's feeling. If you have concerns, try for tests if possible. We have three children. Daughter began talking early, 8 months (birth order also plays a role in this I think) late walking typical balance of "if they are doing one thing they can focus on the other later," typical doctor catch all. We followed this rule of thumb for our son who was born 2 1/2 years later. 18 months, climbing, walking, organizing chess pieces from tallest to smallest, great pattern recognition skills. But we also noticed he was just babbling. Asked the doctor about this and she stated that big sister was just talking for him, he is great at pattern recognition and cross motor skills, he will catch up! Very reassuring, but there was something creeping in the back of my mind thinking that it was not right. I ask my wife and she went with the doctor's advice so I conceded the issue. (continued)posted 02/06/2013 by a BabyCenter Member
I am having the same problem with my 16 month old daughter as well. She only babbles 'ma ma' and 'da da' but I am trying to find ways I can help her to say at least a word or two that a lot of children her age do from what I have studied about in my early childhood classes and witnessed while I was in college. I am in the process of finging things to do as well. One thing that I have heard from what I have studied and what my friends told me worked for them was to talk to them using normal words like you were talking to one of your friends and not babblig back to them. I have also heard that it is a good idea to say what something is as they pass it. For instance, when I am walking her from her room to the kitchen area she will point or touch something like the wall or door and as she does it I just say what it is. I have also heard that it helps a lot when they hear other children thier age talking that it will encourage them.posted 01/29/2013 by a.thorne09
My son is 17 months as well and he doesn't talk very much either. The dr did say he is fine, but it does worry me and sometimes I'm a little embarrassed or jealous when I see other kids his age talking better. He basically only says momma, dadda, and he just started saying bye bye a week ago. My niece is 3 weeks older than him and says probably 10-15 words. I have heard that girls learn a little faster than boys and tend to talk better. Some things I have been doing with him to try and get him talking are to say the names of his body parts like this is your nose and point to his nose and then say this is mommy's nose and point to mine. Then sometimes I ask him where is your nose and he might point to his ear, but I think it is helping him to learn and hopefully he will start saying these words soon.posted 07/11/2009 by Mellissar
If you feel your child is not speaking you should first speak with your pediatrician. My pediatrician advised us to contact early intervention when my son was 18 months old. We met with the state rep and she asked us questions and called us 2 days later and advised our son did not meet criteria. When my son turned 2 he still did not speak more than 2-3 words. Up until this pt my son stayed home so I made the decision to put him in daycare with other children his age so that he would see what other children his age were doing. I have no friends with children his age and my other two children are MUCH older (21 and 16 yo). I called EI again and they evaluated him and he was accepted into program. He now meets with speech therapist once a week. He is doing much better but still not at same level with children his age. Pls keep in mind all children learn at different pace, my son is advanced in other areas but I feel he just wasn't ready to talk to us yet. Sometimes patience is key!posted 01/08/2013 by wyatt_s_mom
My daughter, Jessica,is 27 mths old and she says mom, ma,dada,hi, bye. She Babbles alot and she'll say uh Oh. It does worry me some what that she is not talking like most toddlers. Should I be?posted 01/07/2013 by a BabyCenter Member
i did post when my little one was 3years old and not talking..just few words juice..water..want ..yes..no..was worried he wouldnt talk at all. Had his ears checked.. and everything was ok. After he started pre-school and had speech therapy there. it helped him a lot..we noticed that he would understand all we talked but woudnt talk back.. my doc told he was lazy.. getting things without trying a lot.. so he wouldnt make the effort to talk. we pretended we wouldnt understand.. then repeat the question slowly it was two words and he is chatter box. would talk when he wanted to.. and not always answer all the questions. he talks to us.. but not his teachers...am worried about that. If they dont have any trouble listening and forming words.. they will take some time. no point in pressuring them and our selves...know how it sound to those who lose sleep with worries. one baby step a day.. and they copy a lot from older kids..having them around talkative kid does helpposted 01/06/2013 by a BabyCenter Member
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It takes me a while to make these so don't be surprised if I go a few months without putting any new ones up!
:: Home :: Bases :: Dolls :: KiSS :: About Me :: Links ::
Bases! You can use them for pixel art (or dolls or whatever you want to call them. XD) or KiSS (Otakuworld and the KiSS Café can explain what those are better that I can XD) or whatever else you can think of.
A few rules, though:
1. You don't have to give credit for these bases, since most of them are traced. Don't claim they're your own, though!
But, it's the polite thing to link back to either this site, or unknoen.deviantart.com
(I mean, don't you hate it when you see something on a base you really like, but can't find a link to it?)
2. No money should be involved with these bases! No real money, at least. That means, don't sell dolls made on these bases! Don't pay people for dolls made on these bases!
Money in virtual economies (forum currency and the like) is okay, though, only if there is no way (within the rules) to convert that currency into real money. That means places like Gaia are fine, but ones like IMVU are not!


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text:
Record Quake Boosts Insurer Disaster Costs 90% to $38 Billion
The record Chilean earthquake and winter storm Xynthia in Europe led catastrophes that caused insurance industry costs from natural disasters to surge 90 percent this year, according to Aon Corp.
Insured losses from natural disasters climbed to $38 billion from $20 billion a year earlier, according to a report today from Aon Benfield, a unit of the world's largest insurance broker. Economic losses, which included uninsured costs of an earthquake in Haiti and flooding in Pakistan, totaled $252 billion, a fourfold increase from last year.
"Nature was very active in 2010," Chicago-based Aon said in the report. "Major earthquakes in Haiti, Chile and Indonesia caused thousands of fatalities and widespread damage. Vast floods persisted for many months across portions of Asia. Severe weather outbreaks in the United States and Australia spawned tornadoes, damaging winds and destructive hail."
The reinsurance industry, led by Munich Re, Swiss Reinsurance Co. and Warren Buffett's Berkshire Hathaway Inc., provided "ample" protection for the Chile quake that cost insurers $8.5 billion, the year's most expensive disaster for the industry, Aon Benfield Analytics Chief Executive Officer Stephen Mildenhall, said in a statement. Reinsurer capital is at a record level, and supply of the funds to backstop insurers may outstrip demand, lowering rates next year, he said.
February's winter storm Xynthia, which struck France, Portugal, Spain, Belgium and Germany, was the second-most expensive natural disaster for insurers, costing $3.65 billion, Aon said.
New Zealand, Haiti
Industry losses from the New Zealand earthquake in September were $3.05 billion, the third-most expensive disaster of the year, according to the report. PartnerRe Ltd. said this week that industry losses from the quake could climb to $5.5 billion on the higher-than-expected number of claims.
The January earthquake in Haiti was the most destructive event this year, claiming about 230,000 lives and damaging or destroying 350,000 structures, Aon said. About 1 percent of the $8 billion in economic losses were insured.
Flooding in Pakistan in July and August damaged or destroyed 1.7 million buildings, killed about 2,000 people, and caused an estimated $30 billion in economic losses, Aon said.
The U.S. sustained $2 billion in insured losses from storms in the Great Plains and another $1.5 billion from flooding in the Nashville, Tennessee, area in April and May, Aon said. The U.S. escaped major storm damage in an Atlantic season that produced the second-most number of hurricanes in the last 25 years.


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loretta weinberg
NJ Dems Bash Christie's State Of The State Address [AUDIO/VIDEO]
Governor Christie Gets an "F" on Women's Issues, Says Report Card [AUDIO]
When it comes to issues that matter to women, Governor Christie could use some work.
Chris Christie, Loretta Weinberg Revisit "Bat" Comment
NJ Female Dems Claim Christie Silent On Equal Pay [AUDIO]
Equal Pay For Women A Must Say NJ Female Dems
NJ's Paid Family Leave Law Hits Four Year Mark [AUDIO]
State Senate President Steve Sweeney, Majority Leader Loretta Weinberg and advocates for working families celebrated the fourth anniversary of New Jersey's Paid Family Leave Insurance program by attending a birthday party in honor of the law.
Three-Way Race To Win Your Support For A NJ Tax Cut Plan [VIDEO]
NJ Rethinks Two Key Open-Government Laws
Chris Christie Stands By His Budget Estimates [AUDIO]
Yesterday, the State Senate Budget Committee got the latest state revenue projections. The non-partisan Office of Legislative Services (OLS) briefed the panel during the morning's session.


text:
"Phelps gets into the blood and guts of the story." -Gregg Olsen
Killing Her Wasn't Enough. . .
Sixteen-year-old Adrianne Reynolds couldn't unravel the twisted tangles of jealousy and domination complicating her new life in East Moline, Illinois. What began as a fresh start after a troubled home life in Texas ended with Adrianne's body charred, stuffed into garbage bags, and scattered. It seemed the work of hardened criminals, but the truth was far more astonishing:… (mehr)
Verlag: Pinnacle ( 1. August 2011)
Format: EPUB
Seitenzahl: 320 Seiten
Dateigröße: 1,8 MB
Schutz: DRM
Sprache: Englisch


text:
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text:
Dennis A. Schaffer, 50, of 1446 Ridge Road, was charged with failure to control Monday after he drove off the right side of Ohio 601 and hit a sign.
No citation was issued Monday after Walter R. Bring, 69, of Elyria, hit debris on U.S. 20 while he was heading east. The debris punctured a hole on the right side of his fuel tank.
Michael A. Mullaney, 28, of 209 Woodland Ave., Willard, was charged with failure to yield the right-of-way Wednesday in the Peru Center Road collision with the vehicle driven by Jennifer L. Sword, no age given, of 3086 Ohio 103, Willard.
Kandice R. McHenry, 19, of 4347 Hartland Center Road, Collins, was charged with failure to control Wednesday after she swerved to miss an animal on U.S. 20 and went off the right side. She overcorrected, re-entered the road, overturned and went off the right side of the road. McHenry hit an embankment, overturned again and the vehicle came to rest on its roof. She was not injured.
Joyce K. Dennis, 47, of 4821 Sherman Norwich Road, Willard, hit a deer Thursday on Washington Road, east of Drake Road.
Heidi R. Burkhalter, 40, of 167 Gallup Ave., was charged with speeding Thursday after she hit the vehicle driven by Kristine D. Purenciu, 36, 4933 Tumney Trail, on N. Ohio 61.
Assisted North Central EMS with a patient at 9:53 p.m. Wednesday at 29 Hawthorne Drive. Returned to station at 10:09.
Assisted North Central EMS with a patient at 7:46 p.m. Wednesday at 39 1/2 S. West St. Returned to station at 8:07.
Assisted North Central EMS with a patient at 7 p.m. Wednesday at 300 E. Ohio 61. Returned to station at 7:42.
Helped North Central EMS with a patient at 5:50 a.m. Thursday at 100 Furniture Parkway. Returned to station at 5:53.
Joseph C. Gray, 42, 2402 1/2 Ohio 113 E., Milan, was charged with failure to yield half of the roadway Thursday in the North West Street collision with the vehicle driven by David F. Joyce, 50, of 11617 Ohio 113, Milan.
Jesse Reising, of Norwalk, was arrested Thursday on a warrant in connection with a DUI conviction. He is serving a three-day sentence at the Huron County Jail.
A Norwalk resident reported Thursday his foster son was being unruly. The 15-year-old juvenile was taken to the station, where he met with his probation officer and later was released to his foster father.
A Wooster Street resident reported Thursday his bicycle was found abandoned in his yard.
A Hanford Road, Wakeman, resident reported someone stole a clay pigeon launcher from a shelter on his property Wednesday.
An Old State Road resident reported there was a slit in the center container of a package of Molts applesauce he bought at a Westwind Drive business Wednesday. He was referred back to the store.
An Ohio 99, Willard, resident reported suspicious vehicles Wednesday.
An area resident requested Wednesday a deputy check on the well-being of her 5-month-old granddaughter living on Neal Zick Road, Willard. The complainant accused the mother of allowing a registered sex offender to baby-sit the child and reported the allegation to Huron County Children Services.
A Maple Ridge Road, Willard, resident reported tools were stolen from his home Wednesday.
A Townline Road, Willard, resident reported someone vandalized his mailbox Wednesday.
An East U.S. 20, Wakeman, resident reported an electric shaver and toothbrush were found in a vacant mobile home Wednesday.
Responded to a "general duress" alarm activation Wednesday on Hartland Center Road, Collins.
An area resident reported Wednesday loud music was coming from a nearby church.
Responded to a domestic violence complaint Wednesday on Greenwich Milan Townline Road, Norwalk.


text:
Are you Jacob Jensen?Claim your profile
Publications (3)11.84 Total impact
Article: Characterization of Highly Efficacious Allosteric Agonists of the Human Calcium-Sensing Receptor[Show abstract] [Hide abstract]
ABSTRACT: We discovered structurally novel human calcium-sensing receptor (CaSR) allosteric agonists and compared their pharmacology to phenylalkylamine calcimimetics. 1-Benzothiazol-2-yl-1-(2,4-dimethyl-phenyl)-ethanol (AC-265347) activated CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays with potencies of 30 and 10 nM, respectively. (S)-1-Benzothiazol-2-yl-1-(2,4-dimethyl-phenyl)-ethanol) [(S)-AC-265347], the S-enantiomer of AC-265347, was approximately 10- to 20-fold more potent than (R)-1-benzothiazol-2-yl-1-(2,4-dimethyl-phenyl)-ethanol) [(R)-AC-265347]. The phenylalkylamines cinacalcet and calindol had activity similar to that of AC-265347 in cellular proliferation assays but less activity in PI assays. All compounds had reduced activity when extracellular Ca(2+) was removed, indicating that they cooperate with Ca(2+) to activate CaSRs, and all activated CaSR isoforms with the N-terminal extracellular domain deleted, indicating that they interact with the transmembrane domains. In both cases, AC-265347 and therefore (S)-AC-265347 were significantly more efficacious than the phenylalkylamines. Mutations E837A(7.39) and I841A(7.43) strongly reduced phenylalkylamine-induced signaling, but not AC-265347- or (S)-AC-265347-induced signaling, suggesting different modes of binding. AC-265347 and (S)-AC-265347 stimulated significantly greater responses than cinacalcet or calindol at each of four loss-of-function human polymorphic CaSR variants. AC-265347 did not inhibit the CYP2D6 cytochrome P450 isozyme, unlike cinacalcet, which is a potent CYP2D6 inhibitor. In rats, AC-265347, (S)-AC-265347, and (R)-AC-265347 each reduced serum parathyroid hormone (PTH) with a rank order potency correlated with their in vitro potencies. AC-265347 and (S)-AC-265347 also reduced plasma ionizable calcium ([Ca(2+)](o)). AC-265347 was orally active, and its plasma concentrations correlated well with its effects on serum PTH. Thus, these highly efficacious CaSR allosteric agonists represent leads for developing therapeutic agents with potential advantages over existing therapies.Journal of Pharmacology and Experimental Therapeutics 03/2011; 337(1):275-84. DOI:10.1124/jpet.110.178194 · 3.97 Impact Factor
Article: Discovery of a class of calcium sensing receptor positive allosteric modulators; 1-(benzothiazol-2-yl)-1-phenylethanols[Show abstract] [Hide abstract]
ABSTRACT: 1-(Benzothiazol-2-yl)-1-(4-chlorophenyl)ethanol (1) was identified as a positive allosteric modulator (PAM) of the CaSR in a functional cell-based assay. This compound belongs to a class of compounds that is structurally distinct from other known positive allosteric modulators, for example, the phenylalkylamines cinacalcet, a modified analog (13) potently suppressed parathyroid hormone (PTH) release in rats, consistent with its profile as a PAM of CaSRs.Bioorganic & medicinal chemistry letters 10/2010; 20(19):5918-21. DOI:10.1016/j.bmcl.2010.07.077 · 2.42 Impact Factor
Article: Synthesis and Evaluation of Dibenzothiazepines: A Novel Class of Selective Cannabinoid-1 Receptor Inverse Agonists[Show abstract] [Hide abstract]
ABSTRACT: A novel class of CB1 inverse agonists was discovered. To efficiently establish structure-activity relationships (SARs), new synthetic methodologies amenable for parallel synthesis were developed. The compounds were evaluated in a mammalian cell-based functional assay and in radioligand binding assays expressing recombinant human cannabinoid receptors (CB1 and CB2). In general, all of the compounds exhibited high binding selectivity at CB1 vs CB2 and the general SAR revealed a lead compound 11-(4-chlorophenyl)dibenzo[b,f][1,4]thiazepine-8-carboxylic acid butylamide (12e) which showed excellent in vivo activity in pharmacodynamic models related to CB1 receptor activity. The low solubility that hampered the development of 12e was solved leading to a potential preclinical candidate 11-(3-chloro-4-fluorophenyl)dibenzo[b,f][1,4]thiazepine-8-carboxylic acid butylamide (12h).Journal of Medicinal Chemistry 05/2009; 52(7):1975-82. DOI:10.1021/jm801534c · 5.45 Impact Factor
Top Journals
ACADIA PharmaceuticalSan Diego, California, United States
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Secretary of State William Henry Seward negotiated the 1867 purchase of Alaska from Russia, an important step in the rise of the United States as a great power in the Asia-Pacific region. More»
For about a 1% investment of the Federal budget, the State Department yields a large return for the American people by advancing U.S. national security, promoting our economic interests, providing services, and reaffirming our country's exceptional role in the world. Read on to learn how the work of the Department benefits this state's residents.
The Department of State, in partnership with other federal agencies, advances U.S. trade policy objectives by opening new markets for American businesses and workers. Of the 554 Alaska exporters in 2013, 72% were small- and medium-sized enterprises. In 2014, Alaska exports totaled $5.1 billion. Those exports supported 39,540 U.S. jobs. (EB) More»
Alaska hosted 1,626 foreign physicians, teachers, camp counselors, au pairs and others as part of work and study-based international exchange visitor programs. (ECA) More»
The Bureau of International Narcotics and Law Enforcement Affairs (INL) contributed more than $12 million to Alaska's economy by providing jobs and manufacturing opportunities that yielded products and services which directly supported INL missions. (INL) More»
The Bureau of Oceans and International Environmental and Scientific Affairs contributed nearly $450 million to the State of Alaska for participating in the Pacific Salmon Commission, and nearly $145 million to the State of Alaska for participating in the International Halibut Commission, both of which ensure the maintenance of sustainable populations of Pacific salmon and Pacific halibut for harvest opportunities by the U.S. (OES)
The Bureau of Oceans and International Environmental and Scientific Affairs contributed nearly $50,000 to the State of Alaska for partnering with the Institute of the North to work on the Arctic Maritime Infrastructure and Aviation Transportation Initiative, an Arctic Council project. (OES) More»
Click here for more information about Department career recruitment events in Alaska. (HR)
Fulbright Scholarship Awards: 8 Scholars and Students from Alaska (ECA) More»
142 exchange visitors from overseas visited Alaska and 98 Alaska residents travelled overseas as part of the Department of State Educational and Cultural Affairs (ECA) funded exchange programs. (ECA) More»
Diplomat-in-Residence: (Lewis Lukens): Diplomats in Residence (DIRs) are career Foreign Service Officers located throughout the U.S. who provide guidance and advice to students, professionals and the community about Department careers. (HR) More»
Four Brazilian students attended the University of Alaska-Fairbanks through the Brazil Scientific Mobility Program. This program is funded by the Brazilian government and the private sector and sends 101,000 Brazilian university students of science, technology, engineering, and mathematics to study and conduct research abroad. The U.S. is a priority destination for scholarship recipients, and the program strengthens U.S. and Brazilian institutional partnerships, develops a workforce prepared for 21st century opportunities, and contributes to long-term economic growth for both countries. (WHA) More»
The U.S. Ambassador to Mongolia, Piper Campbell, traveled to Alaska in April 2015 for a press conference to highlight the positive impact of the State Partnership Program between Mongolia and the Alaska National Guard. This partnership, entered over a decade ago, allows for military training and exercises as well as disaster preparedness. More»
Refugee Arrivals: 106. The Department works with nine domestic nongovernmental organizations, which have 350 affiliated offices, to place refugees in over 180 communities in all 50 states. These offices work with communities, local volunteers and elected officials to provide a successful start for refugees rebuilding their lives. (PRM) More»
The Department of State facilitates the Alaska National Guard State Partnership Program with Mongolia founded in 2003. (PM) More»
Total Passports Issued: 34,604 (CA) More»
Passport Application Acceptance Facilities: 44 (CA) More»
31 Alaskan families participated in overseas adoptions. The Office of Children's Issues (CI) plays an active role in the intercountry adoption process. Its work is dedicated to assisting parents as they seek to provide a home to orphans abroad. (CA) More»
Diplomatic Security San Francisco Field Office serves Alaska: Diplomatic Security has offices throughout the United States staffed with special agents and contract investigators, who conduct criminal, counterterrorism, and background investigations. Agents assigned to field and resident offices assist in providing support to the protection of the Secretary of State, the U.S. Ambassador to the United Nations, and visiting foreign dignitaries. Liaison with federal and local law enforcement, foreign mission personnel, local officials, and the private sector complements their major responsibilities. (DS) More»


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The hotel was booked for us in Cusco. The hotel is ok, clean and the location is not too far from the centre. The breakfast is not too much but also early breakfast was possible. The bad overall bad rating comes because we wanted to buy tickets to La Paz. The manager/owner pursuaded us to buy the tickets with him.... More
If you own or manage Hotel Maria Angola, register now for free tools to enhance your listing, attract new reviews, and respond to reviewers.


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Election Day
Sponsored By
UTA Political Expert Provides Analysis Of Election Day ResultsUTA political science professor Allan Saxe provides a complete recap the day's results, and gives insight into what the nation's political structure might look like moving forward.
Democrat Wendy Davis Says She Would Welcome Obama VisitDemocrat Wendy Davis says she would welcome President Barack Obama campaigning for her in Texas in the final days of her underdog bid for governor.
Wendy Davis Votes Early, Rejects Talk Of Long OddsTrailing in polls and money with just two weeks until Election Day, Democrat Wendy Davis on Monday cast her ballot on the first day of early voting and rejected talk that her bid for Texas governor is headed for defeat.
County Websites Cause Some North Texas Voter FrustrationOn this primary Election Day some voter struggles began before individuals even arrived to cast their ballots. A number of people in Dallas and Denton County found themselves searching for their designated polling place, after struggling with election websites.
Civil Rights Group: Texas Passive On Voter Turnout Civil rights activists accused Texas officials Monday of not enforcing laws designed to drive voter turnout.
Texas Votes In First Election Day Under ID Law Texas voters went to the polls on Tuesday for the state's first election requiring people to show ID.
Election Day 2012: Constant CoverageElection Day 2012 coverage updated continuously throughout the day and night.
Opinion: Ten Reasons Mitt Romney Lost The ElectionToday, Republicans feel a combination of confusion, disbelief, and anger as to how a slim majority of Americans can possibly want four more years of the Obama administration in the White House. To many, it seems inconceivable that people want to take a chance on more of the same.
North Texans Feeling 'Election Stress'Thousands of North Texans made their votes count Tuesday at the polls. But along with a sense of patriotism, many voters say they've been feeling "Election Stress."
Voters Taking Advantage Of Election Day FreebiesYes, it's your civic duty and participating in the democratic process should be reward enough! Some people call it an abomination, others a pleasant byproduct, but there are a lot of businesses offering Election Day freebies.
Opinion: On Election Day Romney Keeping His Mind On The Business-At-HandObama plays basketball and Romney campaigns on Election Day
Opinion: Ballots Full Of WomenWhile Mitt Romney talks about binders full of women, Democrats have ballots full of women.


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Hey it's Sean Sellers from the Simon Says Get Up Show! Thanks for checking out my blog. Feel free to comment on anything I say here!
How's your dog?
by Sean Sellers
posted Aug 18 2009 4:46PM
Very expensive research tells us that most Simon listeners are "dog people". This is only to say that they own dogs more often than cats, not that they have any distaste for cats. We didn't research that part. The facts show that most of us have at least one dog. With this in mind, we often deal with pet related issues on the GET UP show.
Today, we offered translations of dogs barking. There's a new product out called
Bow Lingual. Here is the audio of our translations: http://www2.987simon.com/listen/dog-translator
Well, it turns out the original inventor of the "Bark Translator" was listening to Simon this morning and called to tell us about it. Unfortunately, she could not get a patent and the invention was sold to a Japanese company. She now produces a cat translator. Here is her website: http://www.animalvoice.com/
What do you think?
When scientists taught a gorilla to speak in sign language, she eventually was able to communicate with her handlers. After she had become fluent in signing, she would sign the same message to the humans around her over and over. After spending so much time humanizing her, all she wanted to say on her own was, "Let me out!"
So, dogs aren't gorillas. They need us...But, are they trying to tell us something? What do you think?
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Recent writing, future events, occasional thoughts of psychotherapist, writer and teacher, Mark Vernon.
Do leave comments or contact me.
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By Mark Vernon on Saturday, December 24 2011, 20:04 - General
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And a very happy Christmas to you, Mark, with thanks for your writings here and elsewhere.
Thanks for your thoughts too.
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The Art of the Sonnetby Stephen Burt and David Mikics
Staff Pick
You can read this book for its remarkable selection from 450 years of English-language sonnets, or delve into the accompanying essays through which Burt and Mikics shed light on why — and how — the sonnet has remained one of the longest-lived verse forms. Notes on language and historical context make older sonnets more accessible; for instance, Mikics points out how Lady Mary Wroth, writing in 1620, inverts standard Petrarchan imagery as she becomes the mirror into which her beloved gazes upon himself in "Pamphilia to Amphilanthus 46" (not to mention his unpacking of those names!). These insightful essays also enrich the reading of contemporary sonnets, as when Burt speaks of the influence of rock-and-roll music on Denis Johnson's "Man Walking to Work" (1987). With 100 poems, The Art of the Sonnet is more than just a reference; it's an energetic romp through a surprisingly versatile art form.
Synopses & Reviews
Publisher Comments:
Few poetic forms have found more uses than the sonnet in English, and none is now more recognizable. It is one of the longest-lived of verse forms, and one of the briefest. A mere fourteen lines, fashioned by intricate rhymes, it is, as Dante Gabriel Rossetti called it, "a moment's monument." From the Renaissance to the present, the sonnet has given poets a superb vehicle for private contemplation, introspection, and the expression of passionate feelings and thoughts.
The Art of the Sonnet collects one hundred exemplary sonnets of the English language (and a few sonnets in translation), representing highlights in the history of the sonnet, accompanied by short commentaries on each of the poems. The commentaries by Stephen Burt and David Mikics offer new perspectives and insights, and, taken together, demonstrate the enduring as well as changing nature of the sonnet. The authors serve as guides to some of the most-celebrated sonnets in English as well as less-well-known gems by nineteenth- and twentieth-century poets. Also included is a general introductory essay, in which the authors examine the sonnet form and its long and fascinating history, from its origin in medieval Sicily to its English appropriation in the sixteenth century to sonnet writing today in the United States, the United Kingdom, and other English-speaking parts of the world.
"The sonnet may well be the poetic form that most often comes to mind when anyone thinks of poetry. Fourteen lines long, in open and closed structures, sonnets have been prominent over the past 400 years of poetic history. In this unusual book — half anthology, half collection of essays — Burt and Mikics, both prolific critics of poetry (Burt is also a poet himself) choose 100 sonnets and for each offer a thoughtful, scholarly, though highly accessible commentary. The oldest poem is Thomas Wyatt's 'Whoso List to Hunt' (1557), and the newest is by the contemporary poet D.A. Powell, first published last year. In between, there's everything from Shakespeare and Wordsworth to Robert Lowell and Lucie Brock-Broido. Of 'Redemption,' George Herbert's sonnet about the Resurrection of Christ, Mikics writes, 'Herbert's Savior... shocks us into attention.' Of one of Ted Berrigan's sonnets, Burt says, 'The disorientation, the wildness, is part of the point: no more organized poem would do.' While this anthology would make a wonderful textbook for a prosody class, its best audience may be anyone who wants to delve deeply into the heart of poetry. Learnd as well as passionate, this book is a delight." Publishers Weekly (Starred Review) (Copyright Reed Business Information, Inc.)
First Things Notable Book of 2010
About the Author
Stephen Burt is Professor of English at Harvard.David Mikics is John and Rebecca Moores Professor of English at the University of Houston.
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Arizona legislator: Revoke age limit for state militia
PHOENIX — A state lawmaker wants the age limit of 45 for serving in the
state militia removed, opening the force designed to be mustered in emergencies
but never used in modern memory to older Arizonans.
But preachers of the gospel, judges, idiots, lunatics and members of the
Legislature would still be barred under the early 20th century law that
Republican Rep. Carl Seel wants to update.
Seel said all he's doing is bringing the age provision in the Arizona
Constitution into modern times. But the parts barring lawmakers, elected
officials, preachers, the totally blind, idiots and lunatics and "persons
convicted of infamous crimes," will remain in the enabling legislation Seel
wants to revise.
The bill is headed to the full House after a routine committee approval Monday.


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This iReport is part of an assignment:
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Melvin, Michigan
Melvin, Michigan
Burn victim
Amanda Tweedale was at home Thursday May 1,2013 at her residence in Clinton Twp,Michigan with her 4 year old daughter Anna Lynn deep frying chicken nuggets when it caught fire & exploded in her face & boiling hot grease poured down her body giving her 3rd degree burns on 54% of her body! Her feet and legs are the worst! Her feet are so bad that they are talking about possible amputation! Mean while they are badly infected from her skin and flesh melting all the way to the bone. She doesnt have any medical insurance & has to undergo multiple surgeries! Please show your support and help me raise money for Amanda Tweedale & her family!!!! Amanda is at Detroit Receiving Hospital in the Burn Unit! Her 4 year old Anna wants her mommy back home with her!!! Please show your support!!!!Detroit Receiving Hospital is treating Amanda wrong! They have been leaving her in the room all day without changing her bedding and without feeding her and without dumping her urine pan! Please Show your support and help her get the medical care she deserves and help her get medical insurance and makesure she gets donations. I made a fundraiser for her www.GoFundMe.com/8xc9ww and I also put donation cups in several differant stores in my community to help her out as well! Please Help her Share her story all around the world!! Show your support!
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Homemade Bi-sexual
Eating Own Cum
WE see no reason to pass up a Nice Warm Homemade Cream Pie
Wine Tasting
It is a wonderful reward when You find just the right wine for the occasion, be it an evening of pleasent stimulating conversation with a friend, a nice meal with someone special, a good wine to set the mood for any evening of sexual bliss or a glass of nice wine to share in the afterglow of that perfect sexual experience.
There's a wine for all occasions, Let's find the ones for us...............
Be Happy
or even a little Kinky
Just Be Happy
F-M-F Threesome
My first wife has a gift of charm and an overwhelming magnetic pull over women. Where ever she is, she seems to just draw the women from all around. It's like a Pidepiper power. She leads and without question or reason they just fallow her lead.
she takes full advantage of this charm. (or power) She has always been, something of a collector. She sorts her collection, according to her varied sexual and bi-sexual interests. I had the honer and privilege of being her, most often used man, for her many, TWO OR MORE GIRLS ON ONE MAN PLAY.
..........................&quo t;GOOD TIMES"................... "THOSE WERE THE DAYS........................
Bloomington, Indiana swm looking for BBW for friendship and sexual fun (FWB)
Kinky Sex
I love having partners use me for their sexual pleasure pretty much however they like
is great!
Being A Couples Fuck Toy
OMG ! That would be incredible! My ultiment sexual desire & goal is to please a couple, together as one. Threr is very little, if anything I would not do to achive that!
Be Happy
D i c k
60 years young swm looking for grannies in the Bloomington , Indiana area for friendship and sexual fun *& pleasure.
Chubby Girls
60 years young swm interested in getting together with chubby women in the Bloomington, Indiana area for friendship & sexual fun.
I love to be Castrated by having my
removed, but have by balls stay.
That would leave me sexual frustrated as i never be able to cum unless a man fuck me
I have been giving serious thought to and about the OTHER sexual partners and what secrets, tecnics, ideas and fantasys many of us even as practicing an open relationship, or partner or multiples there of that many horny people have never had a uniqe masterbation experience that I have found to be one more extreemly erotic as well as entertaining voyeuristic fantasy orgasms, other than solo?
So with that being said I have been very exited about the prospect of hosting a masterbation only meeting, even mixed ideas brought into this genre. Examp;le couples, singles, bi sexual, gay and lesbian, transvestite, and transjender would all be exepted and encurraged to attend. with the only exeption being that for all of us in the straight male groupe would most definitly, at least in my world one female to aloe any or all of the males in in the group to be as in all fareness will have a fantasy, or erotic release. Such as female , married, coup[led singled together or to be watched.
I can imagin how hot it would be to have a woman use any means to let other either, watch, cheer, assist toys and machine offered to all, and above all let your mind enter a manual orgasms , or team cumming, touching licking, groping, or just laying back and using artificial or resonable ialturnitives to aid in the individual, group tease, invite or for the partner to a whole differnt, but never fales to be orgasms free and easy sexual party where discression, is up to the individule, but anyone and every one can come!
I would like to ask all and every on of you in the community if anyone should be exposed to any or or be or informed of this idea, please feel free to add, edit their own secrets. I would really like to know if anyone else would find this exiting ? make your opinion as either, maybe moreTIME, AND ANYWHERE iM GETTING WET JUST THINKING ABOUT IT!
Couples Searching For Bi Males
Older fit bi-man in Dallas likes to meet up with MF couples in the DFW area. Very mellow, horny, and possessed of good sexual stamina.
SWM in Bloomington , Indiana loves his herb & sex.
Looking for people who want to party and have some nsa sexual fun.
I have been toking for 43 years now and love busting a nut when I am buzzed.
2 Guys One Woman
Hello from Bloomington , Indiana.
I am a 60 years young bi swm looking to be a third for bi couples in my area or near by.
I love to eat pussy , suck cock, fuck & get fucked.
NSA, just friendship and some good sexual fun.
Cock Sucking Guys
I simply love to suck cock. Sucking cock is my favorite sexual activity.
Cock Sucking Guys
Live in New Orleans been bi-sexual sucking cocks since
8th grade looking foer men/guys that enjoy sucking cock
Just do it !!!! Open to all oppportunties
Bisexual Women For Couples
Big black hot and sexy couple in Gary, IN, looking for a bi-curious or bi sexual female any race to spend time with and someone that has time for us.
. We would love to have a long term relationship with, from friends to lovers
Couples Dominating Men
I love having a couple dominate and use me for whatever sexual fantasy they like. I would love to find a couple near me near Raleigh NC that would use me like that on a regular basis...
We are a sexy couple looking for other sexy couples for fun and sexual pleasures. We have many fantasy's we want to perform. We are both Bi-sexual so anything goes. We are both very open minded, so again anything goes.
We are a very loving and devoted couple, looking to explore our sexual interests. We are new to this lifestyle but understand our needs, wants, fantasy, and desires. Very open minded to try new things. Interested in exploring her sexual desires to be with another woman and to share her in a threesome.
We are a happily married couple, very committed to each other, and we've recently renewed our interest in this lifestyle. Some things have changed over the years........other things will never change - sex is great...more sex is better...people who enjoy being sexual and enjoy others being sexual...the best! We are looking for couples who share our attitudes, fantasies, and sense of discretion. Interested?
we are a clean,discreet, professional, couple who like to let their sexual desires free when the time is avail. We have a teen child so our free time is limited. We dont have any hangups on sexual orientation, race, size - though not really into drastically overweight. We are just average builds and pretty good looking
i'm a very easygoing openminded person who is into most forms of sexual pleasure. i enjoy being with all people and love to cater to thier sexual needs. i'm willing to try anything once to better my self and to keep the flow of pleasure open to all. i'm your's for the taking. i'm average looking. i'm 5'10",195#,average endowment. i hope to hear from you soon so that i may give you what you desire. have a wonderful day and happy hunting.
. Fun, and outgoing describes myself well.I seek opportunities to enhance my sexual relationships, and with luck yours as well. Honesty, and open-mindedness, are the foundation in all we believe, thriving on the need to, surrender all of ones self to intoxicating, " sexual experiences life has to offer.(Why not?) However I am NOT open minded to persons who seek to create drama, mind trips, or personality performances( fakes).
Funny easy-going down to earth couple looking to explore with couples and bi men/women. We love to have sex and play with toys. Since we are both bi, we both love to suck cock and eat pussy. We both love a good dick in us but Ms Bravo does not do anal. We love to take pictures of us and our sexual encounters, but it is not required. We are very sexual people who like to get things moving quick. We are very descreet and would like our partners to be also. We are willing to travel a good distance if you are willing to have some fun. SORRY BUT WE ARE UNABLE TO HOST AT OUR PLACE !
We have been exploring alternative sexual lifestyles together and would love to find a couple to play with and if the situation worked out to spend time together outside of playing. I find the female body so attractive and I love to play. Tony and I both enjoy a bit of the wild side and are adventurous when it comes to sexual experience. We love spending time together and are open to new experiences.
Easy going professional male who would like to enjoy the company of a single bi-sexual male or a couple where the man is bi-sexual. I've experienced a threesome with a bisexual male who enjoyed oral sex and also was a top. We had a great time but would also like to explore the possibility of meeting someone who enjoys oral sex and being a bottom. I'm not out to pressure anyone into doing anything they're not comfortable with....but also don't have alot of time meet people who only think they might be interested. Please drop me a note if anything you've read so far peaks your interest and we'll go from there.....Thanks!
very playful, love to have fun for all who are involed, 6ft, 245lbs,thick,strong build, very little body hair, 7.5 penis, very new to bisex lifestyle, but willing to try many activities, I believe that honesty and kindness are very important, I would enjoy being friends with the people I get togather with, in addition to great sexual activity; I've enjoyed delightful sexual activity with women and now wish to explore passion with men, and couples; I truly enjoy an open mind and free thought, with a passionate desire to please each other
i am bi-curious, Corey is bi-sexual. I love to read and get jokes on my email. I am a bbw. We bothhave a great sense of humor and like most everyone we meet. corey is a bbm, into woodworking. We travel a long way to work so weekends are when we like to meet people. We are very open minded people and both of us are nudist.We live way out in the woods so we like to be nude all the time. (hard to put clothes on to go to work) lol!! I am interested in young, petite women for bi-sexual fun.
fun sexual and very oral couple
white married bi-male looking for others to satisfy my and their sexual needs.
I am bi male that likes sex. I love oral sex. Will do most anything sexual.
An older guy that is turning more to other bi men to expand on my sexual activities.
happy married couple looking to expand sexual pleasures either together or apart
33yo bi-curious male. I am excited to be a member of this site. After reading some forums and profiles I realized that the people here use the site to express their sexual interests that are normally taboo. So, I guess my purpose here is taboo too, but thats cool here. Was took back when I realised that people were posting xxx pictures for the world to see. I have to say that when i pulled my cock out to take the first xxx pic I was so turned on by it. Have enjoyed the comments from other users regarding my pics. I am here because I have a cock curiosity. My girlfriend would not be cool with it, so I am out looking for a fun couple that would like to invite one more to experience some sexual fantacies. Specifically I would like to give a double blowjob with a woman. She put the cock in my mouth and I put it in hers until he cums. If anyone is interested or just wants to talk about it please feel free to contact me anytime. I enjoy the pics and stories that other members have to share. Bisexual MMF videos and pictures are really hot too. Might want to make some of my own or someone elses.
I have made homemade soap it not that hard to do.
Also being in the music world I have also may Christmas cd.
I pump my nipples too I use cockpump hooked to homemade cup. If any one wamts more info go to google and search for female pumping then find newart forums its slow but full of great info on this subject. Alf
I always make oyster dressing and fry a turkey and bake a ham.
Stuffed bell peppers
A pineapple salad
Home made cannied yams
Green Peas
Seafood gumbo
I also try to fry some pickles
Garlic mashed potatoes
homemade bread
being single and love to cook hoidays I go all out
Ham, Turkey Cornbread dressing with sausage and giblets mashed potatoes collard greens or any other type of greens with smoked turkey or hamhocks, coconut cream pie sweet potato pie pumpkin cheesecake broccoli homemade bread.
I'm an interesting male for a sexual or non-sexual relationship,(perfer sexual)
I'm a 50 something Bi-Curious Virgin who's had a few sexual experiences with men although they've been well and good to me; I yearn for the feeling that I could get from having my Clit licked and sucked on by a bi-sexual female. This is something that I fantasize about whether I'm awake or sleeping. I came to the Bi-
ual Playground in hopes of fulfilling this desire that I have to do this. Feel free to drop me an email
My husband and i are looking for a bi sexual couple M-F or F-F or a bi sexual girl that is looking for some fun.. Bi sexual girl that may want to be in it for long term. let us know ..
I had occassional fleeting fantasies about man2man sexual activity starting in my 20s. By age 39 [10 years ago] I finally acted on it. My primary attraction is to women but with a strong secondary sexual attraction to men - my sexual attraction list in order of priority is:
1. my wife
2. men
3 other women
My non-sexual attraction list in order is:
1. my wife
2. other women
3. men
Sounds very familiar! Jen and I usually always let it be known that the first time we meet it's going to be non-sexual. That way one uncomfortable situation is handled if things don't work out. We just call or e-mail back within a few days and let the ugy know that while we enjoyed his company, for some reason we just didn't feel that sexual attraction we need. Or let him know we just don't think we will "click" and that we never try and force anything, but that he was really great and we wish we would have felt a stronger sexual connection. So far that has worked and been honest but without getting into mean or uncomfortable specifics.
I am solely attracted to women, but fantasies of sex with men and couples. I think about oral and even anal sex with men on a frequent bases. I married and enjoy sex with my wife. She doesn't know about my membership to BP, but I have been a member here much longer than we have been married. I am straight in relationships, but bisexual in my sexual desires. Some people have a strong sexual side and are uninhabited in sexual desires. Doesn't make them gay to want sex
Many people are 100% gay or lesbian, and are drawn sexually and emotionally only to partners of the same sex. Others are completely heterosexual, bonding in sexual and intimate relationships only with people of another sex. But what about everybody else? A significant percentage of people do not fit neatly into either of these categories, because they experience sexual and emotional attractions and feelings for people of different genders at some point during their lives. For lack of a better term, they are called bisexuals, although many people prefer to call themselves "pansexual," "non-preferential," "sexually fluid," "ambisexual," or "omni-sexual."
============================== ============================== =========
Bisexuality is the potential to feel sexually attracted to and to engage in sensual or sexual relationships with people of either sex. A bisexual person may not be equally attracted to both sexes, and a degree of attraction may vary over time. Self-perception is the key to a bisexual identity. Many people engage in a sexual activity with people of both sexes, yet do not identify as being bisexual. Likewise, other people engage in sexual relations only with people of one sex, or do not engage in sexual activity at all, yet consider themselves bisexual. There is no behavioral �test� to determine whether or not one is bisexual.
Why stick yourself in a 'sexuality box'. Don't be hetero, homo or bi - sexual. Just be sexual.
and enjoy whomever you are with
Hi, I am a bi-sexual female. Married but only I have sexual encounters out of marriage, he watches. Would love to get to know you if interested just let me know.
We are seeking a bi-sexual female for sexual-friendship and fun(wink)
IN Brooklyn New York.
I want to be used by a female for her sexual service in any way she desires. I can be yours and your hubbies sexual slut or play toy, to be used for servicing his cock, or any other way you please.
hi nipples we are in tacoma, wa and we areloking for a f friend to have soem sexual and non-sexual fun with. we need someone we can have an ongoing friendship wit hand the other as well. take a look at our profile and let us know if you'd like to get together.
looking for sexual activity with females or males or couples, really wanting to expand my sexual life and stop wondering about it !!!!
Sign Up for Free!
What they like best about the site: �I can meet people who share my sexual desires.
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text:
William Kelly
I CORINTHIANS 12 The subject, which the apostle covers in this chapter, was one most deeply needed at that time by the Corinthian saints, and is still much needed today.
Booklet, 31 pages
#1478-56, $1.95
More Info
Thorough. Detailed. Scholarly. Newly translated from an amended text, with prefaces to the First, Second and Third Editions.
Hardback, 398 pages
#1030, $12.95
Helpful surveys of: Acts, James, Peter's Epistles, John's Epistles, Jude and Revelation. New Testament Introductory Lectures Volume 3.
Hardback, 600 pages
#1114, $14.95
Helpful surveys of: Acts - James - Peter's Epistles - John's Epistles - Jude - Revelation. NT Introductory Lectures Volume 3.
Paperback, 600 pages
#1113-15, $17.95
The resurrection of Christ calls me to live thoroughly unto God.
20-Pack of 4-Page Leaflets, 4 pages
#7196, $1.95
A bound set of this monthly magazine of articles on scriptural subjects. Covers the period June 1856-July 1920. Edited by W. Kelly and W. Hocking. Supported by full index of article titles and Scripture references.
Set of 16 Double Volumes & Index
#1600-15, $449.95
Edited by William Kelly
1 Text DVD, PDF Format With Image, Searchable
#7337-56, $20.00
Unabridged. See "The Holy Humanity of our Lord Jesus Christ" for the abridged version.
Hardback, 64 pages
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Practical instruction from Lectures on the New Testament Doctrine of the Holy Spirit (pp. 70-77).
20-Pack of 8-Page Leaflets, 8 pages
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In "Lessons on the books of Chronicles" you will … Find how God wants us to react to a day of ruin. Consider God's ways in divine counsel. Meditate on our God's ways in government.
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Considered by many to be the best book on the subject. Contents: One Body - One Spirit - The Assembly and Ministry - Worship, the Breaking of Bread, and Prayer - Gifts and Local Charges - The Resources of the Faithful in the Ruins of Christendom.
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Leviticus Set, Volume 6.
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text:
However, the writing group did not feel the evidence is strong enough to say gum disease causes heart disease or stroke.
"So far, there is no conclusive evidence [of a cause-effect relationship]," Lockhart said. "If cause and effect is someday proven, it will probably be fairly minor," he said.
Other experts agree.
"If patients have heart disease and gum disease, they have two separate problems," said Dr. Robert Myerburg, a professor of medicine in the division of cardiology at the University of Miami Miller School of Medicine.
Those with gum disease and heart disease should be aware, Myerburg said, that treatment of gum disease is not going to improve their heart problems. "Nor will treatment of your heart problems improve your gum problems."
In agreement with the new statement, too, is the American Academy of Periodontology, said Dr. Pamela McClain, a periodontist in Aurora, Colo., and president of the academy. Its members treat patients with gum disease. "The academy agrees that science doesn't support a causal relationship between periodontal disease as a direct cause of cardiovascular disease," she said.
However, she disagrees with Lockhart's statement that if a cause-effect relationship is found, it will be minor. "It's hard to predict. We may find a stronger link," she said.
"The message should be, we can't say there is proof of a causal relationship," McClain said. "We know there is definitely a link between these."
Bottom line, all experts agree, is that if you have either disease, you need treatment.
And if you have gum disease, you can't expect treatment to prevent heart disease.
More information
To learn more about the heart, visit the World Heart Federation.
SOURCES: Peter Lockhart, D.D.S., professor and chair of oral
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