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By Matt Snyder
Young Marlins slugger Mike Stanton's birth name is actually Giancarlo Cruz-Michael Stanton. He just started going by Mike in school because of the constant mispronunciations.
"It got really annoying having seven classes having to correct seven different people every single day.'' he said (Fish Tank Blog). "Mike is part of my middle name so it was the easiest (solution). But I never changed it because I didn't like it.''
And now, Stanton says he's going to be introduced -- at least in all home games -- as Giancarlo Stanton from this point forward.
The Fish Tank blog post notes that Stanton is pretty easy-going with the name choices, so it's cool if you keep calling him Mike. His teammates have a wide variety of names they call him.
"Everything,'' he said with a smile (Fish Tank Blog). "Cruz. Giancarlo, Mike, Mikey, Big Mike, Big Foot, Bam-bam. Man-Child. I respond to 25 different names.''
Stanton, 22, is one of the brighter young stars in all of baseball. He amassed 56 home runs before his 22nd birthday (which was last November). Last season, his second in the majors, he hit .262/.356/.537 with 34 homers, 87 RBI and 79 runs. If he continues to develop on this path, I'm pretty sure Marlins fans will be happy to call him whatever he wants.
For more baseball news, rumors and analysis, follow @EyeOnBaseball on Twitter, subscribe to the RSS feed and "like" us on Facebook.


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See All Contributors »
MINNEAPOLIS, Minn. Senior Lauren Breunig is one day closer to the end of her illustrious Cyclone career as she competed in the 200 free on day two of the NCAA Championships.
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subset: commoncrawl


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I am using rackspace cloud files, i setup 2 websites. The first website is just fine. The second one, it has been a few days, when i test Cloud files upload it will show:
Error: Empty hostname / CNAME list.
Both websites are using the same CHICAGO node, why is this happening?
The weird is, i try upload the themes files is ok, shows green.


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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
all the expressive, creative, and inspirational personalities of our community!
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Scoring courtside seats to the sold-out basketball game calls for an outfit topped by this open, cream jacket! Your hip yet laid-back ensemble looks extra cozy - and super cool - when worn alongside the structured ivory shell and vegan-faux-shearling-lined collar of this knit cover up. Wear it with dark-wash skinnies, tall, sleek boots, an oversized, metallic pendant, and a tank emblazoned with your team's insignia - spectators will be as entranced by your outfit as they are with the game!
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How NYC Communities React to Interracial Relationships - A Survey
- Where
- When
- November 14, 2013
Historically, interracial relationships have not been socially accepted. Even though Richard and Mildred Loving fought and the won the battle for interracial marriages to be legal, we still live in a day when these relationships aren't accepted. My group project is a study to find out how NYC communities react to his/her interracial relationships. This could include his/her neighborhood community, familial community, etc.
The survey is completely confidential and does not require you to submit any personal information (aside from the name of the neighborhoods/boroughs). Thank you so much in advance if you choose to participate :)
Please feel free to share!!


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Best of News
White lion cubs sit in a cage at a house where more than 200 live... Photo d'actualitéAssis,Bangkok,Cage,Droit,Faune,Lion,Lionceau,Petit de mammifère à fourrure,Système judiciaire,Thaïlande,VerticalPhotographer CHRISTOPHE ARCHAMBAULTCollection: AFP 2013 AFPWhite lion cubs sit in a cage at a house where more than 200 live wild animals including 14 white lions were discovered last week, on the outskirts of Bangkok on June 19, 2013. Police said the lions were believed to have been brought into the country using permits for sales to zoos, but instead offered to private buyers. Thailand has a reputation as a hub of international wildlife smuggling to feed strong demand in Asia for unusual pets and traditional medicines made from animal parts. AFP PHOTO/Christophe ARCHAMBAULT (Photo credit should read CHRISTOPHE ARCHAMBAULT/AFP/Getty Images)


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micoach is all you need to get the results you want.
Your SelectionClear All
I bought my pair of Ultra Boost back in April and now have over 300 miles on them. The shoes have far exceed expectations. I have been running exclusively in adidas boost products for over two years now. When these were coming out for release I was a little bit skeptical mainly due to the price. I got to run a couple of test miles in a pair of ultras and quickly realized it was the real deal shoe. The upper knit is super comfortable and makes for a breathable design on any run. The extra boost material give a comfortable landing on every step. One thing with a boost product is that you can run in the shoe day after day without reduction in the performance of the midsole. The rubber flex sole is a draw back but after three hundred miles the sole has seen a reduction in the rubber knobs but the sole is still in tact. I am thinking that I can get to 800 miles on these shoes. Excited to see what new colors will be coming in 2016. Thanks adidas!!! ... read more
Nice looking trainer arrived on time and was a good fit but my sporty son only wore it a few times and the thin fabric upper started to develop a hole. Rather disappointed that the material was not strong enough to withstand greater wear and tear. ... read more
Really in love with the design and color scheme. These are really comfortable and have a certain mystique because it looks great for casual or for running purposes. I am starting to dig the boost technology. Hire me Adidas? Would love to work at adidas ... read more
My title pretty much sums it up. First, the good: This has to be one of the most comfortable shoes I've ever worn. Appearance is great; Fit is great (I wear 9.5, but went with a half size up and don't regret it). The "sock-like" weave fit is so comfortable, and the boost material really seems second to none. Here's the MAJOR problem: the outer most sole wears faster than any other shoe I've ever owned. I'm generally a fast walker and occasional light jogger. The "nubs" are now completely gone and starting to cause very slippery conditions when wet or on slick surfaces, and I've only had these shoes about 6 months. For the life of me, I wanted to give this shoe a 5-star rating, but for $180, you would think "the greatest running shoe ever" would put a quality and revolutionary outer sole that would last? Why not use your Continental rubber soles like on other Adidas shoes? So disappointed, Adidas. ... read more
These shoes are the most comfortable shoes I've ever worn. They do fit a little tight but because of the knit material making it more of a sock feel. I'd recommend going a half size up for more room but overall these shoes are amazing and very stylish as well. ... read more
When I first received the shoes, I was a bit disappointed because I wasn't sure if the material quality looks as good as the picture. I kept them still because I really needed a new pair of shoes. THEY RUN SMALL - I have a pair of adidas that were sz8 and they are big on me so I ordered 7.5 for this pair but they are really small!!! I had to make a return and purchased half size bigger. Even sz8 was a bit tight at the beginning but after just wearing them 3 times, they are now perfect! They look SO GOOD with my outfits and they are very comfortable - I especially like that they do not have laces that makes stretching really easy and nice!!! The more I wear them, I love them more!!! ... read more
Very bouncy and comfortable on the feet. I have problems with my left foot and numbness. However, my left foot felt pretty good in these shoes wile running an 8 km run. I usually start feel some pain after 4 km but I am able to run the whole 8 km without pain. ... read more
A big fan of how the shoe looks and it gets its fair share of compliments (I wear it casually). It's super light, provides fairly good support, and the mesh cover definitely keeps things cool. A few critiques: The insole moving around is a problem for the first few days but it settles in. A week later, not a problem when putting it on but the insole does still pop when taking the shoe off. I've also found that the lower edge of the shoe (white and red) picks up scuffs pretty easy. They wipe off but kind of annoying. None of this would scare me away from purchasing again. ... read more
This shoes is so comfortable I had to buy it in two colorways. I recently bought some air max 15 prior to buying my first ultra boost in solar red. The boost are way more comfortable to run in than the air max. I recently picked up some ultra boost in a core black colorway when the website had my size available and I have to say, the primeknit material feels a lot different than the primeknkt material on my solar reds. I'm not sure if I got a defective pair but other than that it is still a nice shoe. They also look great so you can wear them with almost anything. ... read more
Ultra Boost shoes fit like a glove and have been perfect for all workouts in the gym. I have used my pair indoor for about six months and there is no sign of wear at all. They grip perfectly on the slickest wood floor during weight training. They fit like part of the body and perhaps the most important point is that they are not noticed while running on the treadmill - it is as though they are part of you. Hardly any weight. Added bounce. Best workout shoes ever! ... read more
My son and I walked by a new Adidas shoe store in the mall and decided to go in. He was looking for a new pair of running/walking shoes and was trying some on, the sales person was telling us about these new shoes Ultra Boost shoes and here exclusive Adidas soles and tops that are so comfortable it's like walking on air and they boost you while running ? My son was ready to leave but I tried the shoes on and convinced him to also. We didn't take them off and wore them home . I'm on my feet all day and I love these shoes ! Probably the best shoes I've ever owned ! P.S. I was wearing a new pair of New Balance running shoes when we went into the store ! ... read more
Since I've started using these shoes for running, I ordered another pair for work (I work 12-hr shifts in an ICU; lot's of running around and comfort is crucial to survive a day or night without blisters). These shoes are light and airy; excellent for whatever kind of running you do - from short jogs to 12-hr work days on your feet. Highly recommended. ... read more
Personally, the boost material is the best cushioning system ever invented. These response boosts were perfect for me because I run but also do strength training. The placement of the boost material provides a studier base the the shoe rather than a pure or ultra boost. I now have a pair of ultra, pure, and response boost and I would recommend an ultra boost for a running or casual shoe. The response boost is a perfect training shoe. ... read more
I love the shoe. Very comfortable and you can really feel the energy return. Only draw back is that i feel my heel slipping out when doing my runs, had to remove the insole for my foot to go deeper in the the shoe and for my heel not to slip out. ... read more
Aside from the metrics of a narrow space at the ball fo the foot, this choe breathes well, is light on the foot and is comfort in flat terrain. I would avoid a too-rocky path as the light weight of the sole does not add to rock protection. ... read more
I really wanted to love this shoe, especially since I got the new navy colorway with the 30% off code. I can honestly say the cushioning is way better than anything else. Nothing out there like it. And after reading that others thought they were narrow, I didn't find that. What ultimately made me return them is that the toe box wasn't tall enough. My big toe even made the primeknit stick up. Otherwise they are perfect and I loved the snug fit, except for my big toe. ... read more
When I first put them on, they felt a bit snug but they're designed to be that way. I'm a sz 11.5-12 depending on the sneaker and the 12 works fine for me. They just mold to your foot after a few hours and I haven't wanted to take them off my feet since! I own at least 100 pairs of sneakers and these are in the top 3, as far as comfort and they look great! ... read more
I'm an avid runner and I'm always in the gym. In the streets of NYC or in the gym, I can't say I've ever been more satisfied with a running shoe. I use these sneakers for all my fitness activity, energy return is great, tie-down is great! ... read more
I own the original Energy Boost, Energy Boost 2, Supernova Boost 6 and Supernova Boost 7. After chatting with online personnel, I decided to give the Response Boost 2 a try. It is somewhat ironic, that a shoe named "Response" totally lacks the cushioning and "response" that made the Boost shoes such a hit!! Rides very firm and has little "rebound" qualities of the aforementioned shoes. I will only use this shoe for short 2-4 mile recovery runs. ... read more
Needs to have either all white or all black midsole. They could at least make middle black and the rest white. but only back white and front black is ridiculous. Had to take them back just because of that.. another perfect shoe ruined by one small detail. ... read more
I wanted to wait 4 months before posting my review to understand the durability, and all I can say is WOW! I have put down very long mile runs and also interval training, varying from 100m-800m pseudo sprints, and these shoes are great! Very comfortable, and the comfort doesn't diminish in time! AWESOME, THANKS ADIDAS! ... read more
I found the all black pair today while shopping for running shoes, though they won't be used for that. Maybe it's because I'm on my feet all day at work (10hrs/6 days week in safety boots) that I like these so much. When I tried them on in store I felt like I was in heaven. While the Pure Boost's are good, I don't exactly like the mushy feel in the forefoot which is why I passed on them. These fill that void for me since I tend to put lots of force on my heels and want some add'l structure towards the front. Good all around shoe for lounging on my days off! ... read more
This shoe is brilliant. Extremely comfortable and even more stylish. I have trouble finding a good fit as I have a narrow 12-13 men's shoe size. The shoe does fit narrowly, but in my case it is nothing short of perfect. I got a 13 but a 12.5 (my true size) may have fit even more perfectly. I have the triple white and it's beautiful and I get compliments and looks from friends and strangers alike. Highly recommended. Spend the extra 80 bucks and be happy and better than all your Nike wearing peers. ... read more
these are super comfortable! a little narrow and snug fitting but i like it. i went with my regular adidas size (10.5) and they fit nice, i personally wouldn't go up more than half a size as the length is true and they will end up to long. only downside is the boost midsole is impossible to keep clean and the soles wear very fast but if you are just using them for casual wear they should be fine. ... read more
its a really nice shoe, but the only downside is the traction but that's it. I know the 2 is they make it will be better as long as they fix the traction issue. But I love them. I prefer the pure boost for walking but the ultraboost for any work out ... read more


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Business Office
Time to Fill out your fafsa
We understand that cost is a vital factor in your college choice. Even more important, however, is the consideration of value received in exchange for that cost. With our commitment to making quality affordable, Wayland transforms college cost into an educational investment.
Because of the contributions of so many who believe in Christian higher education, the cost of an education at Wayland is among the lowest of any accredited, private university in the south. The allocation to the university's operating fund by the Baptist General Convention of Texas, gifts from alumni, friends and individual churches, as well as a growing endowment, contribute to the university's ability to reduce the cost of attending Wayland.
In addition, the aggressive approach
of Wayland's Financial Aid Office has resulted in
financial assistance for over 95% of our full-time
students. Through institutional, state, and federal
programs, Wayland makes available both merit and
need-based assistance.
WBU has adopted the Code of Conduct established by NAFSAA. For further information see NASFAA's Statement of Ethical Principles and code of conduct for Institutional Financial Aid Professionals
Access NetPartner here!
View your financial aid status and accept awards on NetPartner. Use your student ID and choose to "First Time User" or "Forgot My PIN" to create your PIN numbers. If you have difficulty accessing NetPartner, please contact us at email@example.com .
This form is available in the Financial Aid Office, the Education Service Centers at various military bases, and it can be downloaded from the Internet. You need to check with the Financial Aid Office to ensure that you have submitted all the necessary forms.
All financial assistance must be approved prior to registration. Stop by the Financial Aid Office to see if you are eligible for assistance, or call (210) 826-7595 ext 217.
Please check with the office for hours during registration. The office is closed weekends, university holidays, and during Graduation.
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text: Sue Vaccaro | IBDB: The official source for Broadway Information IBDB: The official source for Broadway Information Official Broadway League sites: - sites - broadway.org broadwayleague.com broadwayfanclub.com kidsnightonbroadway.com stagespecs.org tonyawards.com Quick Search For: In This Category: All Show People/Org. Theatre Season Sue Vaccaro Female See Also: Quintet ProductionsRoger Berlind/Quintet Productions ProductionsAwards ProductionsDate of ProductionsClybourne Park[Play, Comedy, Drama, Original] Produced by Roger Berlind/Quintet Productions Apr 19, 2012 - Sep 02, 2012 2012 Tony Award® Best PlayClybourne Park [winner]Produced by Roger Berlind/Quintet Productions Find out where Sue Vaccaro and are credited together © 2001-2015, The Broadway League, All Rights Reserved. (Copyright and Disclaimer)


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Www.plmtalks.com - PLM talks - PLM ideas in motion. CPDA. Design Systems. Agile Product Lifecycle Management. Oracle's Agile Product Lifecycle Management enables you to strategically manage the complete lifecycle of a product: from the ideation phase through to recycling and retirement.
More than a technology solution, Agile Product Lifecycle Management focuses on process efficiency, rapid innovation, cross-functional collaboration, closed-loop quality control, risk mitigation, and cost-effectiveness. Why Oracle? Oracle offers the most comprehensive, integrated Enterprise PLM applications that leverage best practices, align the value chain, and provide a single source of truth for product data.
Fully configurable, with a proven track record in a range of industries, Oracle's Enterprise PLM applications deliver more business value with less risk at a lower total cost. PLM - Product Lifecycle Management Software Solutions.
Recommendations & Standards. Research Rap: Are Engineers Social? Online They Are! A quick peek into some research on… how active engineers are with social networks.
While attending the PROuser conference, I heard Robin Saitz of PTC talk about a study that they commissioned Forrester Research to develop. The goal of the study was to better understand how active PTC's customers are in social networks. The results surprised me and they didn't, it turns out that engineers and product developers are very active with social computing! The Research Forrester, from what I can see, has taken a significant lead in researching social computing.
About nine out of ten (specifically 89%) of those surveyed use social media and Web 2.0. There is clearly more to the research about how they use it, whether they use it personally or professionally, and other factors. Robin did make it clear that they are using social computing for work as well as personal reasons. My Thoughts Let me keep this short. Why am I surprised? Implications for Manufacturers. PLM Content and Facebook Open Graph « Daily PLM Think Tank Blog. Facebook F8 conference this week was a place for some very interesting announcements that, in my view, may have an impact on PLM too.
I can recommend you to read a good summary of news introduced by Facebook here. In my view, it presents a very interesting dimension in the future development of Facebook. The question I'm asking – should PLM care? Is there something new presented by Facebook, that can catch a focus of current and future PLM development? Web Content Creation Facebook is making next steps in the development of content on the web. Social Graph The notion of connection between social sites is presented in the Open Graph Protocol. PLM Content I see a comparison between the way Facebook is building social web content and PLM content. What is my conclusion? Best, Oleg Like this: Like Loading...
CAD. CAE. Social Product Development. Global PLM (Product Lifecycle Management), Architecture, SOA and Development. This is the home site of Martin Ohly. Originally from the UK and now over 25 years in Germany based in Berlin. I have worked for over 33 years in different areas of engineering and IT. The last 20 years working on large and distributed systems in different application domains - covering factory control, healthcare, SAP deployments, global PLM solutions and most recently concerned with electronic toll collection systems - with many successful and some not so successful large and small projects. Areas of interest My interests lie in several areas: the challenges of building reliable, secure and distributed systems, such as global PLM systems , platforms for supporting global collaborative product development learn from real systems - how they work, why they work - and maybe why they failed (please send me any interesting references, stories, etc - if applicable, I will post these on this site) take pleasure in successful projects - providing useful, performant, reliable, manageable systems.


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block heater
Posted 30 December 2012 - 04:38 PM
From my manual: "an internal thermostat in the plug-end of the cord may exist which will prevent engine coolant heater operation at temps above -18." How do I know if mine has this thermostat? and if it does, how do I disable it? I want mine heating by -10.
Posted 30 December 2012 - 04:46 PM
Posted 30 December 2012 - 05:36 PM
Basically though, if you replace the end of the cord and then only have it plugged in when it's actually below 20F or so..... it probably will never trigger any code and you have a guarantee of a warmer block... It just lets the pistons move slightly easier in the cylinders as it does nothing for the oil in the pan of course.
It's funny when the weather hovers at the 0 F mark..... I can noticeably tell when my block heater cord has passed power and when it hasn't as the truck does labour a bit more when it hasn't. That is with 5W30 Amsoil synthetic in it as well.
Edited by Notamember, 30 December 2012 - 05:38 PM.
Posted 31 December 2012 - 11:45 AM
Any of these 3 options will cause the block heater to now be energized whenever it is plugged in :
1 - You can cut open the small round end of the blister and stick a scrap metal washer in there and re-seal it with tape or silicone. The washer makes contact with both sides and defeats the bi-metallic sensor.
2 - You can cut the thermostat blister completely off and install an new male 3-prong plug (all hardware stores carry them).
3 - You can go to NAPA and order a new, non-thermostatic cord and replace the entire cord from the block heater forward. They come in different length's and you can get a longer one if that works better for you. Look at the cord before you take it home to make sure it has the correct orientation on the block heater end, and is the length you want. NAPA has a bunch of different ones to suit your needs
I have personally done #1 and 3 above. The only possible issue with #2 above is getting a weatherproof rated one and keeping out corrosion.
I have never had the block heater operation set a MIL code, but I don't plug it in if the temp is above +15F. I've been doing this sine 2005.
No worries.
Retrax Rolling Tonneau, Putco SS/Chrome Side Rails, Bushwacker Bed Rail Protectors,Husky Floor Liners
Posted 01 January 2013 - 10:42 AM
2013 Avalanche LTZ. White Diamond Tricoat paint w/Ebony leather. (mine) In person tune by Justin from BlackBear Performance
2005 BMW 645Ci convertible w/only 21k miles
2013 Ford C-Max SEL Hybrid (hers)
Please PM me if you have any questions or concerns.
Posted 01 January 2013 - 12:10 PM
Retrax Rolling Tonneau, Putco SS/Chrome Side Rails, Bushwacker Bed Rail Protectors,Husky Floor Liners
Posted 02 January 2013 - 09:07 PM
Diablew custom tune, Airaid CAI, Gibson Dual Sport Exhaust, Elite Engineering Catch Can, LT275/60R20 BF Goodrich AT KO2, Dealer installed step bars and mudflaps, Putco bed rail bars, Access Lorado tonneau cover, Linex spray-in liner, Husky X-act floor liners, Lund window wind deflector
Posted 02 January 2013 - 09:25 PM
Posted 07 January 2013 - 01:23 PM
I would be happy to look into this for you with the last eight of your VIN. Feel free to contact me privately for more assistance. Thank you.
Tricia, GM Customer Service.
Posted 07 January 2013 - 03:46 PM
Not to highjack the thread but does anyone know where the block heater cord is for a 2012 duramax? Doesn't appear to be in the same place as my old 2005
on my 2013 its on the passenger side taped to a harness by the fender. It was a pain to get the zip tie cut
Posted 26 November 2013 - 07:09 PM
My cord is not where the manual says it should be.... I am afraid that my truck does not have a coolant heater. I am sure that my truck, working in Louisiana in its prior life, never needed a coolant heater. But I am disappointed that I don't have it now that I need it. Does anyone here have advice on installing an after-market heater? Thanks
2008 GMC 2500HD DuramaxCrewCabLongBox4x4
Posted 26 November 2013 - 07:47 PM
My cord is not where the manual says it should be.... I am afraid that my truck does not have a coolant heater. I am sure that my truck, working in Louisiana in its prior life, never needed a coolant heater. But I am disappointed that I don't have it now that I need it. Does anyone here have advice on installing an after-market heater? Thanks
What engine?
ALL Duramaxes have a block heater.
The cord is tie wrapped under the air piping on the passenger side of the engine compartment. (on the engine side of the wheel well liner) It's sometimes hard to find, but it'll be under there.
Posted 30 November 2013 - 10:41 PM
Thanks redwngr Found it.
2008 GMC 2500HD DuramaxCrewCabLongBox4x4
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Sustainable Salmon Feeds Shamu at SeaWorld
Ever wonder where all that seafood consumed by SeaWorld's guests and its wettest performers came from? Certainly not from the aquarium tanks. Although the Shark Encounter certainly looks to hold the capacity. SeaWorld took a careful look at their sources for seafood and decided they could do more to be…


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Credits & Info
- Uploaded
- Apr 5, 2007 | 8:01 PM EDT
- Daily Feature April 6, 2007
- Weekly 3rd Place April 11, 2007
If you liked this, check these out!
Plenty more like this here!
Author Comments
Rated 5 / 5 stars
RAB is GOD!! :D
That was simply the funniest thing ive seen on newgrounds since the last RAB episode. Seriously that has 2 b the gr8est flash produced by the hands of man lol cant w8 4 the next one man.
Rated 4.5 / 5 stars
Talk about irony
I had just finished wathing RAB 17 and then I see this one just appeared wile I was contemplating when the next epesode would come out.
talk about extra funny!
Rated 5 / 5 stars
Pretty good, and I think I have the answer. Is Puppy's penis different?
Rated 5 / 5 stars
I actually helped vote this into the portal!
Wow! IT'S A GREAT FRIGGIN MOVIE!
Rated 4 / 5 stars
Entertaining as always.
But how come no one died?


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Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter (BLOCk-CTI)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of the BLOCk-CTI study is to evaluate the safety and effectiveness of the Blazer® Open-Irrigated Ablation Catheter for the treatment of sustained or recurrent type 1 atrial flutter. This study will compare outcomes in patients treated with the Blazer® Open-Irrigated Ablation Catheter to outcomes in patients treated with open-irrigated radiofrequency ablation catheters that have received FDA market approval for the treatment of type 1 atrial flutter.
Atrial Flutter
Device: Blazer® Open-Irrigated Ablation Catheter
Device: Control Catheter
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
|Official Title:
|Clinical Evaluation of the Blazer® Open-Irrigated Radiofrequency Ablation Catheter for the Treatment of Type 1 Atrial Flutter
- Procedure-related complication-free rate [ Time Frame: 7 days post-procedure ] [ Designated as safety issue: Yes ]A procedure-related complication is defined as an adverse event that results in death, a life-threatening complication, or a persistent or significant disability/incapacity or required intervention to prevent a permanent impairment of a body function or damage to a body structure. All adverse events related to the investigational or control devices or ablation procedure will be considered procedure-related events.
- Acute success rate [ Time Frame: 30 minutes after the last radiofrequency application in the cavo-tricuspid isthmus ] [ Designated as safety issue: No ]Acute success is defined as demonstration of bidirectional cavo-tricuspid isthmus block (ie, lack of electrophysiological conduction through the isthmus) 30 minutes after the last radiofrequency application in the cavo-tricuspid isthmus with the investigational or control catheter only.
- Chronic success rate: all treated patients [ Time Frame: 3 months post-procedure ] [ Designated as safety issue: No ]Chronic success is defined as freedom from recurrence of type 1 atrial flutter at 3-months post-procedure for all treated patients.
- Chronic success rate: acute success patients [ Time Frame: 3-months post-procedure ] [ Designated as safety issue: No ]Chronic success is defined as demonstration of acute success and freedom from recurrence of type 1 atrial flutter at 3-months post-procedure. Only randomized patients with acute procedural success will be included in this endpoint.
|Study Start Date:
|January 2011
|Study Completion Date:
|January 2014
|Primary Completion Date:
|September 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Blazer® Open-Irrigated Ablation Catheter
Patients treated with the Blazer® Open-Irrigated Ablation Catheter
Device: Blazer® Open-Irrigated Ablation Catheter
Blazer® Open-Irrigated Ablation Catheter
Active Comparator: Control Catheter
Patients treated with an open-irrigated radiofrequency ablation catheter that has received FDA market approval for the treatment of type 1 atrial flutter
Device: Control Catheter
Open-irrigated radiofrequency ablation catheters that have received FDA market approval for the treatment of type 1 atrial flutter
Detailed Description:
The BLOCk-CTI study is a prospective, multicenter, single blind, 1:1 randomized study. The study is designed to demonstrate that the safety and effectiveness of the Blazer® Open-Irrigated Ablation Catheter are non-inferior to the safety and effectiveness of the control catheters. In this study, the control catheters are open-irrigated radiofrequency ablation catheters that have received FDA market approval for the treatment of type 1 atrial flutter.
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- At least 1 documented episode of type 1 atrial flutter in the 180 days (6 months) preceding enrollment documented by 12-lead ECG, Holter monitor, rhythm strip, or transtelephonic monitor
- Patients are clinically indicated for catheter ablation
- Patients receiving oral anti-arrhythmic drug therapy (class I or class III) for a tachyarrhythmia other than type 1 atrial flutter must be controlled on the anti-arrhythmic drug for a minimum of 30 days prior to enrollment. If type 1 atrial flutter was documented prior to the development of other tachyarrhythmias, this 30-day period is not required.
- Age 18 or above, or of legal age to give informed consent specific to state and national law
- Patients are competent and willing to provide written informed consent to participate in the study and agree to comply with follow-up visits and evaluation
Exclusion Criteria:
- Any prior right atrial cavo-tricuspid isthmus ablation or any cardiac ablation for non-atrial flutter arrhythmias within 90 days prior to enrollment
- Cardiac surgery within 90 days prior to enrollment
- Myocardial infarction within 60 days prior to enrollment
- Current unstable angina
- Patients who cannot have anti-arrhythmic drugs (class I and class III) prescribed for the treatment of type 1 atrial flutter stopped on the day of the procedure
- Patients regularly prescribed amiodarone within the 120 days (4 months) prior to enrollment
- Documented atrial or ventricular tumors, clots, thrombus, or have a known clotting disorder within 90 days prior to enrollment
- Implantation of permanent leads of an implantable device in or through the right atrium within 90 days prior to enrollment
- Direct remedial cause of atrial flutter (e.g. thyroid disease, pericarditis, pulmonary embolic disease)
- Atypical or scar-based flutter
- Patients with New York Heart Association Class III at the time of enrollment or New York Heart Association Class IV heart failure within 90 days prior to enrollment
- Patients with an ejection fraction less than 30% within 90 days prior to enrollment
- Clinically significant structural heart disease (including tricuspid valve regurgitation, tricuspid valve stenosis, tricuspid valve replacement, Ebstein's anomaly, or other congenital heart disease) that would preclude catheter introduction and placement, as determined by the Investigator
- Any cerebral ischemic event (including transient ischemic attacks) within 180 days prior to enrollment
- Contraindication to anticoagulation therapy based upon published guidelines
- Creatinine greater than 2.5 mg/dl or creatinine clearance less than 30 mL/min within 90 days prior to enrollment
- Any other significant uncontrolled or unstable medical condition (e.g. sepsis, acute metabolic illness)
- Enrolled in any concurrent study without BSC written approval
- Women who are pregnant or plan to become pregnant within the course of their participation in the investigation
- Life expectancy less than or equal to 2 years (730 days) per physician opinion
Please refer to this study by its ClinicalTrials.gov identifier: NCT01253200
Hide Study Locations
|United States, Alabama
|University of Alabama at Birmingham
|Birmingham, Alabama, United States, 35294
|United States, California
|St. Jude Medical Center
|Fullerton, California, United States, 92835
|Regional Cardiology Associates
|Sacramento, California, United States, 95819
|United States, Colorado
|Colorado Springs Cardiologist, P.C.
|Colorado Springs, Colorado, United States, 80907
|United States, District of Columbia
|Washington Hospital Center
|Washington, District of Columbia, United States, 20010
|United States, Florida
|West Coast Arrhythmia Center
|Hudson, Florida, United States, 34667
|Tallahassee Memorial Hospital
|Tallahassee, Florida, United States, 32308
|United States, Georgia
|Emory University Hospital
|Atlanta, Georgia, United States, 30308
|Georgia Health Sciences University
|Augusta, Georgia, United States, 30912
|United States, Kansas
|University of Kansas Hospital
|Kansas City, Kansas, United States, 66160
|United States, Kentucky
|Central Baptist Hospital
|Lexington, Kentucky, United States, 40503
|United States, Massachusetts
|Brigham and Women's Hospital
|Boston, Massachusetts, United States, 02115
|Caritas St. Elizabeth's Medical Center
|Boston, Massachusetts, United States, 02135
|United States, Michigan
|Henry Ford Hospital
|Detroit, Michigan, United States, 48202
|United States, Nebraska
|Nebraska Heart Institute
|Lincoln, Nebraska, United States, 68526
|United States, New York
|Strong Memorial Hospital of the University of Rochester
|Rochester, New York, United States, 14642
|United States, North Carolina
|Moses H. Cone Memorial Hospital
|Greensboro, North Carolina, United States, 27401
|United States, Ohio
|Cleveland Clinic Foundation
|Cleveland, Ohio, United States, 44195
|Ohio Health Research Institute
|Columbus, Ohio, United States, 43214
|Ohio State University Medical Center
|Columbus, Ohio, United States, 43210
|ProMedica Toledo Hospital
|Toledo, Ohio, United States, 43606
|United States, South Carolina
|Medical University of South Carolina
|Charleston, South Carolina, United States, 29403
|United States, Texas
|Texas Cardiac Arrhythmia Research
|Austin, Texas, United States, 78705
|Hall Garcia Cardiology
|Houston, Texas, United States, 77030
|United States, Virginia
|Sentara Norfolk General Hospital
|Norfolk, Virginia, United States, 23507
|United States, Washington
|Swedish Medical Center
|Seattle, Washington, United States, 98133
|Principal Investigator:
|Tom McElderry, MD
|University of Alabama at Birmingham
No publications provided
|Responsible Party:
|Boston Scientific Corporation
|ClinicalTrials.gov Identifier:
|NCT01253200 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 21, 2010
|Last Updated:
|April 16, 2014
|Health Authority:
|United States: Food and Drug Administration
Keywords provided by Boston Scientific Corporation:
Type 1 Atrial Flutter
Typical Atrial Flutter
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Additional relevant MeSH terms:
Atrial Flutter
Arrhythmias, Cardiac
Cardiovascular Diseases
Heart Diseases
Pathologic Processes
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
ClinicalTrials.gov processed this record on October 09, 2015


text:
Małgorzata Starczewska-Krzysztoszek
Member of the Economic Council
Małgorzata Starczewska-Krzysztoszek participates in sessions of the Economic Council. She provides opinions on drafts of legal regulations and assesses the implementation of the government's economic and social objectives.
- Lecturer at the Faculty of Economic Sciences of the University of Warsaw
- Chief Economist of the Polish Confederation of Private Employers "Lewiatan"
- Member of the Tripartite Commission on Social and Economic Issues