text:
Study of ALV003 in Healthy Adult Volunteers and Subjects With Well-Controlled Celiac Disease Following a Gluten-Containing Meal (FED)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
ALV003-0812 is a study of the safety and tolerability of a study drug (ALV003) in healthy adult volunteers and in patients with well-controlled celiac disease, following a meal that contains gluten.
Celiac Disease
Drug: ALV003
Drug: Placebo
Phase 1
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Endpoint Classification: Safety Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Basic Science
|Official Title:
|A Phase 1, Two Stage, Single-Blind, Single Dose, Placebo Controlled, Dose Escalation, Crossover Study of the Safety and Tolerability of ALV003 in Healthy Adult Volunteers and Subjects With Well-Controlled Celiac Disease Following a Gluten-Containing Meal
- Safety and Tolerability [ Time Frame: Throughout ] [ Designated as safety issue: Yes ]
|Estimated Enrollment:
|Study Start Date:
|March 2008
|Study Completion Date:
|October 2008
|Primary Completion Date:
|October 2008 (Final data collection date for primary outcome measure)
|Assigned Interventions
Placebo Comparator: A
Drug: Placebo
Placebo to be administered via intragastric tube
Active Comparator: B
ALV003 (Active Study Drug)
Drug: ALV003
Doses via intragastric tube at dosages of either 100 mg, 300 mg, 900 mg, or 1800 mg
Detailed Description:
ALV003-0812 (the FED study) is designed to evaluate the safety and tolerability of a single dose of the study drug, ALV003, administered at one of four different dose levels, and following a test meal containing a small amount (1 gram) of gluten. ALV003 has been demonstrated to proteolyze (assist with the digestion of) various forms of gluten (gluten flour, wheat bread) in laboratory studies and in animals. Celiac disease has been estimated to affect 1% of the population of the United States, is related to gluten, and has a wide range of clinical manifestations including chronic gastrointestinal symptoms, malabsorption, and bone disease.
|Ages Eligible for Study:
|18 Years to 45 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Ages 18 to 45 years (inclusive)
- Healthy volunteers, in good health on the basis of medical history, physical examination, and laboratory values to include: hematology, chemistry, urinalysis, and liver function tests.
Subjects with well-controlled celiac disease (CD), in good health with the exception of CD
- history of biopsy-proven CD in past 5 years
- on gluten free diet for at least 8 weeks prior to enrollment
- tTG or DGP titers within normal limits (≤ 15 IU)
- no flare in symptoms for the past 8 weeks
- Male or non-lactating, non-pregnant females who are postmenopausal, sterile or using at least two acceptable and highly effective birth control methods
- No systemic biologics may be taken for at least 6 months prior to Visit 2 and through 24 hours post-dose at Visit 3 Other than birth control, no prescribed medications, NSAIDs or aspirin may be taken for at least 7 days prior to Visit 2 and through 24 hours post-dose at Visit 3.
- No probiotics may be taken for at least 5 days prior to Visit 2 and through 24 hours post-dose at Visit 3.
- No over-the-counter medications and supplements may be taken for at least 3 days prior to Visit 2 and through 24 hours post-dose at Visit 3
- Body Mass Index of < 30 kg/m2
- Have understood and signed an Informed Consent Form
- Able and willing to comply with study requirements
Exclusion Criteria:
- Positive urine test for alcohol or illegal drugs at screening
- Positive breath test for Helicobacter pylori
- History (within the last 5 years) of inadequate acid secretion, either through a pentagastrin stimulated acid secretion test or fasting intragastric pH 2.5 or greater assessed by passage of a gastric pH probe in the fasting condition
- Aspirin or nonsteroidal anti-inflammatory drugs within 7 days prior to nasogastric or orogastric intubation at Visit 2
- The subject has received an experimental drug within 30 days
- History of substance abuse within the past 5 years
Clinically significant abnormal lab values, as determined by the PI
- Liver Function Tests > 2.5 times Upper Limit of Normal (ULN)
- Serum Creatinine > 1.5 mg/dL
- Hemoglobin (Hb) < 10 g/dL
- Hematocrit outside of the normal range
- Platelet count < 150,000
- Serum Potassium, Prothrombin Time (PT), Partial Thromboplastin Time (PTT), or white blood cell count (WBC) outside of the normal range
- History of tobacco use within the last 6 months
- History of untreated or active peptic ulcer disease, esophagitis, motility disorders or any GI diseases in the past year
- Chronic use (more than once a week) of antacids, H2 receptor blockers or proton pump inhibitors
- Alcohol consumption of > 2 standard drinks equivalents per day
- Positive pregnancy test within 7 days prior to study drug administration
Medical history (Healthy volunteers)
- gluten intolerance
- first degree relative diagnosed with celiac disease
- history of food allergies or digestive enzyme deficiencies
- history of any medically significant condition considered by PI to adversely affect participation
- chronic disease or condition
Medical History (well-controlled CD subjects)
- history of any medically significant condition (other than CD) considered by PI to adversely affect participation
- chronic disease or condition other than CD
- history of severe reactions to low doses of gluten/accidental exposure to gluten
- History of a condition that is contraindicated for nasogastric or orogastric intubation
- Known allergy or hypersensitivity to any of the components of the test meal, placebo, study drug, E. coli-derived proteins or the 25% dextrose and water solution that will be used to flush the tube immediately following dosing
Please refer to this study by its ClinicalTrials.gov identifier: NCT00669825
|United States, California
|Clinical Applications Laboratories
|San Diego, California, United States, 92103
|Clinical Applications Laboratories, Inc.
|San Diego, California, United States, 92103
|Principal Investigator:
|Vijaya Pratha, MD
|Clinical Applications Laboratories
Additional Information:
No publications provided
|Responsible Party:
|Vijaya Pratha, MD, Principal Investigator, Clinical Applications Laboratories Inc.
|ClinicalTrials.gov Identifier:
|NCT00669825 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 21, 2008
|Last Updated:
|February 17, 2010
|Health Authority:
|United States: Food and Drug Administration
Keywords provided by Alvine Pharmaceuticals Inc.:
Celiac Disease
Additional relevant MeSH terms:
Celiac Disease
Digestive System Diseases
Gastrointestinal Diseases
Intestinal Diseases
Malabsorption Syndromes
Metabolic Diseases
ClinicalTrials.gov processed this record on October 09, 2015


text:
Barco expands portfolio of mid-range LED solutions
Kortrijk, Belgium, 17 March 2010 – Barco announces it has acquired the products, intellectual property (IP) rights and know-how of Element Labs, an LED video systems expert based in Santa Clara, California. With a focus on mid-end market requirements in rental, staging and fixed installations, the Element Labs products complement Barco's existing high-end product range.
"This expands Barco's portfolio for the mid-range markets," Eric Van Zele, Barco's President and CEO, comments. "Element Labs' products in these markets have proven their worth on many occasions and perfectly complement Barco's more high-end oriented market portfolio."
Paul Matthijs, VP of Barco's Video & Lighting Solutions business, continues: "Element Labs' products have added a spectacular dimension to numerous concerts, events, corporate headquarters and flagship stores around the world. This transaction will help to accelerate the turnaround which is under way in our Video & Lighting activities, by enabling Barco to address a wider segment of the market, and further leveraging Barco's existing sales, marketing, and service capabilities."
read more

subset: commoncrawl


text:
Aggregate consumer debt fell again in the third quarter, by $74 billion, continuing the nearly four-year downward trend in household debt. As of September 30, 2012, total consumer indebtedness was $11.31 trillion, 0.7% lower than its level in the second quarter of 2012 and down $1.37 trillion from the 2008Q3 peak.
Non-mortgage consumer debt increased by 2.2% to $2.7 trillion. The increase was due to a boost in student loans ($42 billion), auto loans ($18 billion) and credit card balances ($2 billion).
Overall, delinquency rates improved slightly in 2012Q3. As of September 30, 9.0% of outstanding debt was in some stage of delinquency, compared with 9.1% in 2012Q2. About $1.01 trillion of debt is delinquent, with $740 billion seriously delinquent (at least 90 days late or "severely derogatory").


text:
Recent questions
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text:
Nashville tries to reboot its neglected areas with a new form-based zoning code.
The story of the Bottletree and how a single great music venue can make a huge difference to a city.
America is aging quickly, but some cities are welcoming more seniors than others.
It's the nation's most spread-out city. Can an ambitious new transportation plan change that?
When it comes to allocating resources to remove snow, cities can often only guess and hope for the best
A round-up of the strangest city highlights from alternative weeklies around the country
Why the world's most popular tweeters are clustered in a handful of American cities—and Brazil
A survey of 55 major U.S. cities shows big gains in many places, but plenty of regional variation


text:
Meet the Money Doctors
We've assembled a volunteer panel of qualified CPAs that have attained the Personal Financial Specialists (PFS) credential for comprehensive financial planning to act as Money Doctors and answer questions from consumers regarding their financial planning issues. The program is offered as a public service and is designed to help and protect consumers by providing guidance on basic financial planning issues.
Shawn Adamo, CPA/PFS
Shawn is a CPA/PFS located in Northern NJ. Earlier in his career he worked for several Fortune 500 companied before beginning his career as a financial planner. For the last 20 years he has worked exclusively as a financial planner and has been recognized nationally as an expert in this field.
Kevin Brosious, CPA/PFS
Kevin Brosious is president and founder of Wealth Management, Inc, a fee-only financial planning firm with offices in Allentown and Plymouth Meeting, PA. Kevin specializes in personal financial planning for retirees and pre-retirees and wealth management (asset allocation and portfolio management services). Wealth Management, Inc is a registered investment advisory (RIA) firm.
Robert Chapman, CPA/PFS
Robert Chapman is the founder of Compass Wealth, LLC, with over 20 years of financial services experience as a Personal Financial Specialist, CPA and CMA. At times quoted or interviewed in the local, regional and national media for his technical expertise, Robert excels at providing clients with comprehensive customized and integrated strategies for their specific financial situation, including advice on risk management, investments, taxes and planning. His passion for the financial industry is evident in his proactive communication with clients on up-to-date legislation and approaches to wealth strategies.
Cory S. Colquette, CPA/PFS
Cory has extensive experience in the fee-only financial planning and wealth management business. He is an owner of Integra Wealth, an independent wealth management firm in Chattanooga, TN. Cory specializes in providing total wealth management solutions to clients and helping them achieve their goals.
Joe DePascale, CPA/PFS
Joe DePascale currently serves as President of a $1.5 billion trust company specializing in a wholelistic and independent approach towards financial planning. Besides attaining the CPA/PFS designation I am also an Accredited Investment Fiduciary Analyst (AIFA) and a Certified Mutual Fund Specialist (CMFS).
Justine Devito Tenney, CPA/PFS
Justine DeVito Tenney, CPA/PFS, CFP, MBA, is a partner with WeiserMazars LLP, specializing in providing audit, tax, and consulting services to law firms, professional service firms, not-for-profit organizations, high net worth individuals and family groups. She also provides outsourced family office functions, including business management for high net worth individuals and family groups, as well as their trusts and foundations
W. Patrick Harmon, CPA/PFS
Pat has 25 years of experience in the financial services industry and currently serves as his firm's shareholder in charge of financial services. In this capacity, he provides comprehensive tax and financial planning, strategic asset allocation and management, and investment management solutions to the firm's clients.
Jay L. Heller, CPA/PFS
Jay Heller, CPA, PFS, is the CEO of HJ Wealth Management LLC, he began his career as a CPA advising individuals and business owners. Jay has 35 years of experience as a financial advisor and is the co-author of The Progression of Wealth® book.
Michael A. Horlick, CPA/PFS
Michael has been providing financial, tax and investment planning advice to individual clients and their families for over 21 years. After working for private banks, accounting firms and a large planning firm, Michael founded an independent, fee-only firm providing comprehensive advice to clients. In 2012 he merged his firm with Southern Wealth Management, a fee-only registered investment advisory firm. His focus continues to be helping clients meet their individual objectives, whether that is a comfortable retirement, saving for college, or leaving a legacy.
Andrew M. Kark, CPA/PFS
Andy Kark graduated from the A.B. Freeman school of Business at Tulane University in 1990 with a BS in Management and a concentration in accounting. For the past 18 years, Andy has been a partner at M.Z. Kark & Associates, Inc., an SEC Registered Investment Advisory firm in Denver, Colorado.


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4.01 Introduction to Bank Management
Programme Duration - 5 Days
Programme Background & Objectives
Management is core to organistional performance. Its role in resource allocation, planning, performance management and individual attitude cannot be underestimated.
· Expose participants to contemporary trends in principles and practice of management
· Assist participants to update and strengthen their conceptual skills in the management process.
· Assist participants to apply their knowledge in their daily activities
Target Group
· First level managers
Indicative Programme Content
· Dynamics of Modern Organizations
· Introduction to the management process
· Understanding Organizational Behaviour
· Introduction to Performance Management
· Fundamental Legal issues in Banking
· Introduction to Risk Management & Basel 2
· Introduction to Report Writing
· Introduction to Personal Management
· Business and Professional Ethics
· Corporate Grooming


text:
Golf holidays in Eastern Cape
Book an Eastern Cape golf holiday and look forward to exploring the landing place and home to the 1820 settlers.
Previously part of the Cape Province, the Eastern Cape became a separate province in 1994 and the rugged coastline and pristine beaches make it a popular tourist destination.
A choice of quality golf courses includes Bushman Sands Golf Course where the 18-hole championship course was designed by South African golfing legend Gary Player. The course follows the banks of the Bushmans and New Year's Rivers, resembling the earliest links courses in Scotland.
Visit the East London Golf Club, skilfully fashioned out of dense coastal bush, hills and dunes just a few metres away from the Indian Ocean. The club has hosted six South African Opens and boasts breathtaking views of the sea.
Or try Royal Port Alfred Golf Club, which is as charming and old-fashioned as you will find in South Africa and is built on rolling hills and sand dunes with stunning views over the Indian Ocean.
We search the latest Eastern Cape tee times and discounted green fees so that you dont have to. Check out our latest information before booking your dream Eastern Cape golf holiday.
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About Vystar Corporation
Based in Duluth, GA, Vystar ® Corporation (OTC Bulletin Board: VYST) is the exclusive creator of Vytex Natural Rubber Latex (Vytex NRL), a multi-patented, all-natural, raw material that contains significantly reduced levels of antigenic proteins and other non-rubber particles found in natural rubber latex and can be used in over 40,000 products. Vytex NRL is a 100% renewable resource, environmentally safe, "green" and fully biodegradable. Vystar is working with manufacturers across a broad range of consumer and medical products to bring Vytex NRL to market in adhesives, balloons, surgical and exam gloves, other medical devices and natural rubber latex foam mattresses, pillows and sponges. For more information, visit www.vytex.com.
Forward-looking Statements: Certain statements in this document are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act. These statements are based on management's current expectations and are subject to uncertainty and changes in circumstances. Actual results may differ materially from those included in these statements due to a variety of factors. Furthermore, the proposed merg
|SOURCE Vystar Corporation
Copyright©2010 PR Newswire.
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Greek Village Menu
Corporations may establish accounts within the NC State Foundation to accept donations from alumni for the purpose of funding portions of their chapter house that are deemed for "educational use" by the IRS. Corporations may also fund their infrastructure assessments through the Foundation. Please contact the Department of Greek Life for further details.
The Collegiate Housing and Infrastructure Act (pdf)
In April of 2009, Congresswoman Shelley Berkley (D-NV) and Senator Pat Roberts (R-KS) introduced H.R. 1547 and S.781 respectively, to amend the Internal Revenue Code to permit organizations (such as many national fraternal organization foundations) to accept tax-deductible contributions for collegiate housing and infrastructure improvements. Currently, donations to these foundations or local Housing Corporations for non-educational housing improvements are not tax-deductible. This proposed legislation could greatly enhance the ability of organizations to fundraise.
Patton Boggs, a DC lobby firm, is working with the NIC, NPC and Association of Fraternity/Sorority Advisors on this important legislation, and many other items of interest to fraternities and sonorities. To find out how you can help (including template letters to contact your representatives), please visit their website at http://www.fraternalcaucus.org or petition your local congressmen and senators to support via Facebook at http://www.cfcfacebook.com.


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Program Performance and Continuous Improvement
Vision - To produce premier aviation professionals by being the leader among collegiate aviation peers.
Mission - Excellence in aviation. To cultivate excellence in all that we do.
Educational Philosophy - Fostering sound practice based on sound theory through instructional excellence.
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Aeronautical Technology graduates should demonstrate:
1. Social and global awareness
2. Ethical decision making
3. Commitment to lifelong learning
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5. Commitment to personal and technical excellence
6. Commitment to promoting aviation safety
7. Appreciation of environmental sustainability factors related to the aviation industry
8. High proficiency in oral and written communication
9. Team orientation
10. Technical excellence (specific to each degree option)
Program Admission Requirements
Program Assessment
Assessment Plan (Including Student Learning Outcomes and Course Alignment Matrix)


text:
Information Technology for the Health Professions, Fourth Edition | 9780132897648
ISBN-13: 9780132897648 See more
Author(s): Lillian Burke; Barbara Weill
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- Apr 7, 2016$32.99
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For courses covering health information technology in any allied health program or nursing program in college, university, community college, high school, or vocational school.
Now significantly expanded and fully updated, this is the ideal information technology primer for readers working in any healthcare field, including allied health, nursing, medical/dental/pharmaceutical assisting, or medical administration. It fully addresses each key issue in contemporary healthcare IT, including the accelerating migration towards electronic health records. New coverage includes: smartphones, tablets, and their healthcare applications; the role of healthcare reform in promoting health IT; EHR meaningful use criteria; new practice management scheduling software; the growth of telemedicine; new problems in public health; interventional radiology; surgery-related nanotechnology; information-related biotech and pharmaceutical trends; expanded applications in psychiatry and rehabilitation; genetic privacy; and much more.
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jGuru Forums
Posted By:
Posted On:
Thursday, August 2, 2007 05:56 AM
I am following a tutorial to create a junit report from an script, currently I am trying to get the junit results to appear in the command console.
when I run the task In eclipse I get this message, the results never appear in the console window.
Warning: Reference application has not been set at runtime, but was found during
build file parsing, attempting to resolve. Future versions of Ant may support
referencing ids defined in non-executed targets.#
what do I need to do in-order to fix this?


text:
I lurve crochet designs in nifty shapes. Check out Missa's Clutch at Knit Pixie. It's simply adorable.
Hey, that's my bag baby, YEAH!! (Can you tell I'm a bif fan of Austin Powers?)
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Please Visit our Site Sponsors
|Thread Tools
|Display Modes
Extreme throttle sensitivity
I have this reoccurring situation...I posted about it before but it stopped for a while and is back again.
PROBLEM: extreme sensitivity to throttle position only in the first inch or so of throttle movement. Its like this , I just barely step on the throttle from idle like when rolling slow or accelerating from a stop and the truck is very jumpy in RPM response and acceleration...like there is alot of HP waiting to be opened up under small throttle positions. Watching the Tach the RPM comes up unnaturally(non linear to pedal travel) and the truck lurches forward.
When it doesnt exeude this condition the Throttle movement is very nice and linear to acceleration response...
Conditions: It happens cold, hot, full op temp ..nothing as far as external conditions makes a difference.
I am running the truck in the STOCK program from my 1705 Superchips tuner. It also demonstrates the same issue in the tow haul mode or the performance tune.so I dont think it is the tuner unless by swapping the tunes back and forth some code got corrupted...I just dont know.
Oil is fresh, no water in Filter bowl, good fuel with stanadyne in it at all times, solid running always other than this intermittant issue..
IT FEELS LIKE a throttle position sensor is giving bad signals out...but I had the truck at the dealer and he hooked up his diagnostic computer and told me all parameters were good like injector pressure , timing.....all of them....( he didnt like the 0603 code tripped from the tuner and I KNOW he wants to blame it on my superchips tuner) but how can that be when the truck does it on STOCK tune??
What else do you guys think I should check?
Thanks for your help
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It works just like a check, except there's no check to write. Simply present your card to make a purchase anywhere VISA is accepted. There are no ID hassles or interest to pay. Your purchase amount is automatically deducted from your credit union checking account.
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Main Content
The adidas® 2012 NBA All-Star Game Western Conference On-Court jacket is made for some serious hoops playing! This full-zip jacket features a sublimated heathered pattern on the body and a mesh lining. The game logo is woven on the left chest and printed on the back.
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Harmonization and Regulatory Coordination
- International Screening Information Data Sets: The International Screening Information Data Sets (SIDS) is the Organization for Economic Cooperation and Development (OECD) program under which data on high production volume (HPV) chemicals is collected and shared. View the SIDS chemical information available through the UN Environmental Program and the SIDS Manual .
- OECD Test Guidelines Program: EPA and the Organization for Economic Cooperation and
Development (OECD) are engaged in a multi-year effort to harmonize the existing test guidelines of the Office
of Pollution Prevention and Toxics (OPPT) and of the Office of Pesticide Programs (OPP) into a single set of
guidelines for EPA/OPPTS (Office of Prevention, Pesticides and Toxic Substances). The project will then
harmonize the OPPTS guidelines with those of OECD. These guidelines are important because they set standards
for acceptable testing that EPA and our OECD counterparts may require of companies when we review chemicals.
The goal of such harmonization is to reduce the burden of repeated testing from chemical companies to meet differing requirements and to foster international efficiency of information exchange and mutual acceptance of test data. The harmonization effort with OECD has been ongoing since 1989. OPPT has published 97 guidelines in the areas of physical chemistry, ecotoxicity, environmental fate, and human health. OECD has published 77 guidelines in the same four areas. OPP has a total of 170 test guidelines which include guidelines for the above four areas as well as for other specific requirements for OPP's evaluation of pesticides (e.g., product identity, composition, application exposure). Currently, all of physical/chemical properties and environmental fate guidelines, 30 health effects guidelines and six ecotoxicity test guidelines have been harmonized between EPA and OECD. Ten health effects guidelines and 13 ecotoxicity guidelines have been harmonized between OPPT and OPP to produce guidelines that are unique to OPPTS.
OECD makes its guidelines available in print form, on CDROM, and on the OECD web site (draft only at the present time). The OPPTS Harmonized Test Guidelines can be found on the EPA web site or can be accessed through GPO Access. To order copies from GPO, call +1-202-512-1800.
- OECD Clearing House on New Chemicals: The Clearing House brings together representatives of interested governments and the chemical industry working cooperatively to reduce overall burdens associated with new chemical notification reviews, while maintaining the high quality of health and safety decisions for new chemicals. The CHNC undertakes and facilitates work aimed at streamlining the New Chemicals notification processes through: enhancing the exchange of information and work sharing on new chemical notification and assessments; facilitating greater mutual recognition of assessments; and progressing towards mutual acceptance of notifications. OECD web site
- Cooperative Arrangement between U.S. EPA and the Australian Government's National Industrial Chemicals Notification and Assessment Scheme (NICNAS): The new agreement, signed at the end of December 2008, provides for exchanges of health and safety data, chemical assessments and expertise. It is the first agreement memorializing and institutionalizing a level of cooperation in chemical management activities with Australia.


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SF Customer Service Fit and Finish Reliability Durability Product Performance Overall Value Product Design
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Reviewed by Peter (Posted on 12/10/14)
Upgrade for my C2 centurion
The lamp went out on my P 60 head so in looking to replace it, I found the KX4. Big difference in power and battery life. Like a whole new flashlight. Great product. Thanks to surefire for not making me buy a whole new one as the C2 is a great body for my rifle.
Reviewed by James (Posted on 11/18/14)
Bought this conversion head for my P60. Easy to install very bright and what a great difference to makes to my work. great tool.
Reviewed by Steve (Posted on 10/31/14)
KX4 LED conversion
I have been a Sure Fire user since way back. Several years ago Sure Fire had a LED conversion for 6P and Nitrolon that I used. It (the previous model) had a tighter beam and not as much spill-over to the side of the beam.
The new KX4 has a very bright beam and out about 30 feet it seems like a flood pattern not a spot. In fog and smoke this scatter is very annoying and makes it hard to see at distance.
I do like the fact that my red & blue filters will fit the KX4 where that didn't fit the previous model LED head.
Thanks Sure Fire for making a bullet proof LED for the Nitrolon lights. If you ever make a tighter beam pattern for these lights I will upgrade.
Reviewed by Jim (Posted on 9/20/14)
Works great
Bought this led conversion for my older incandescent sure fire. Pretty bright and very easy install. Satisfied.
Reviewed by Jeff (Posted on 8/14/14)
LED Conversion Head
Installed the replacement head in a few seconds the output is very bright, I am happy with this repalcement.
Reviewed by Jaime Arredondo (Posted on 6/21/14)
Very bright light and a significant improvement over the P60 bulb. Seems to be overpriced for long time customers but otherwise great.
Reviewed by Sieramike (Posted on 2/3/14)
Works really great, However it is really over priced. I the original light only costs $59.00 dollars then the new light is $99.00 dolars when all is said and done! if there is a next time that this light goes out I will not replace it with another bulb! I will buy a different light that is lower cost.
Reviewed by Timothy Rodriquez (Posted on 1/21/14)
Surefire flashlights and KX4 LED
When you need one, nothing beats a good flashlight. I bought my first Surefire flashlights with incandescent bulbs, but when I tried out the LED, I was sold immediately, and I replaced my incandescent bulbs with LED. The light is very white and intense, and when tested against an incandescent bulb there is no comparison.
I wish I could tel you how long an LED lasts, but I haven't burned one out yet.
The company Surefire is very professional and delivers what they promise. I have never had a problem.
Reviewed by Peter Stoddard (Posted on 1/18/14)
Write a review ... click here.
|Max Output -- White Light
|Bezel Diameter
Any finish and/or color KX4 LED head can be used on any SureFire flashlight equipped with a P60 or P61 emitter. However, for the best match pair flashlight and KX4 version as follows:
- C2L Hard Anodized order KX4 in Hard Anodized
- G2L, G2L-FYL, G3L, G3L-FYL and G2ZL in Black order KX4 in Black Hard Anodized
- 6PL & Z2L in Black order KX4 in Black Anodized
- G2L, G3L & G2ZL in Tan or OD Green order KX4 in Tan or OD Green
- G2 in Yellow order KX4 in Yellow
- Max Output: 120 lumens; Tactical Runtime: 2-3.3 hours, depending on flashlight model
- Virtually indestructible LED regulated to maximize output and runtime
- Precision micro-textured reflector creates smooth, optimized beam
- High-strength aluminum construction; weatherproof O-ring and gasket sealing
- Powder coated, Type II anodized, or Mil-Spec Type III hard-anodized finish for extreme durability
- Weatherproof O-ring and gasket sealing
- Backed by SureFire's No-Hassle Guarantee


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Hi. This is how I hacked the Elmo. Throughout this walkthrough, you can click on the pictures to get a better view of them as they are shrinked down.
This is a directory listing of what you should have in your folder.
The file called temp.inf is the file that you will be working with mostly.
What I did first was to edit this file. I'm not sure what kind of programming
this is. I'm told is some sort of version of C but I'm not sure.
Open the temp.inf file in Notepad and you'll find a bunch of stuff referring to colors until you start scrolling down.
When you find this string of code:
This is the starting line that Elmo says. Ok this is the part where I break it down for you. You seperate words with a + and you have to delay some words with the [#MSEC] code. (I'm not too sure when to use this code so i use it every now and then. The #CHILDSNAME and #FAVCOLOR and all of the other #FAV's are defined in a different file. This will be explained soon.
I have circled what I am talking about below in the picture.
So for programming him I think its pretty much laid out for you. Just play with the words. You may add whatever names are in the Name Folder or some in the sounds folder (I'm not sure if all of them work but I think they do). Heres a sample:
If you open the commrxd.txt file with notepad, you will find personalization options that you can edit. Once again, you may add whatever names are in the Name Folder or some in the sounds folder (I'm not sure if all of them work but I think they do). You can also make it so that names can be sounds..just rename the name file to the name of the sound file and overwright it.. if this doesnt make sense, email me.
Once you're done, open up elmo.exe.
You'll get a window like this with a lady talking about nothing important.
Make sure the Elmo is plugged in and click on Download to Elmo Knows Your Name. Confirm the selections by clicking on the continue button and then it should start sending files to Elmo. Congrats! Thats pretty much it. Unplug Elmo and turn him on. Push his stomach to see if it works. If not, feel free to Email me with questions at firstname.lastname@example.com
Thanks. I hope it works!
(Thanks to Casey Halverson's SeattleWireless post on Elmo)


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Video: Randolph…A Closer Look
So just finished watching the game and there's plenty to talk about. No, I don't foul Prince with that much time up by three. Gallinari has to know that Prince is going left. That's a lesson for him and he has to take it upon himself to know better. A quick score there is no problem (the foul was) they'd just have to knock down FTs in order to win the game in the 1st overtime. Defensively, you want them to get stops, which they didn't, but all things considered that was a pretty gutty and character building performance on the road regardless if it took 50 something minutes from 4 players. The Knicks had to have this game.
That said, I want to focus on Anthony Randolph's cameo. I saw some good things and some not so good things.
Here, several things to like. First, notice the amount of court he can cover defensively. From hedging at the top of the key (more like half court) to under the rim, his length is something that can be very useful in the half court. Granted, he was covering Greg Monroe who is equally trying to get his footing, but that's a good matchup for him. By the end of his run, Randolph was trying to face up and guard Tracy McGrady and that matchup was exposed.
Randolph's coverage led to a miss and a transition opportunity. He caught the ball in the corner and quickly moved it, which led to a wide open Felton 3.
As a trailer the next time down, he had a chance to make a play and went soft, fading from the rim. That shows a lack of leg strength that comes with not really playing at the NBA pace. If he were game strong, he'd catch and take it to the rim, or catch and spin drawing the big man (Monroe) and either finishing or passing to Amar'e. Obviously, the next time down that was a poor shot.
Nice job by Randolph to be patient in transition. He gets the ball to Amar'e and clears to the corner where he's not really a big threat. Fortunately for the Knicks, Charlie Villanueva's idea of help defense is trying to slap at the ball.
Another good effort from Randolph defensively. He sees the drive well and that presence causes an awkward angle pull up. He then does a nice job of freeing himself in transition, yet makes another weak move towards the basket and is bailed out by the official.
In his brief appearance it's easy to see that Randolph is struggling with his offensive footwork and spots on the floor where he can be deemed a "threat." That has an offensive-minded coach uneasy. Is he a five? A four? A three? That is unclear right now in this offense.
Defensively, he can guard slight 4s and can help off non-shooters. He has range and length.
But he'll need more game reps to shape up his offensive skills and explosiveness. The question is….when does that happen?


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David Beckham's underwear collection will be in your local H&M at the beginning of February, and the soccer player turned "bodywear" designer is doing everything he can to make sure you want to buy it. Including being bashful about the kinds of demands he has for his underwear.
RELATED: WATCH: David Beckham Goes Undercover As A Target Employee
In an interview with The Daily Telegraph, Beckham talked about the new collection, how he decided to distribute it with H&M (they got on the phone with him within 48 hours of hearing he was interested in doing the line) and how becoming an underwear designer fits into his career plans. but he also talked about what he needs in a pair of shorts, and does it awkwardly, too.
"Briefs," he ventures, "are what I mostly wear. When playing, definitely." Boxer short-wise, he confesses admiration for those that Mark 'Marky Mark' Wahlberg once modelled for Calvin Klein. However, he concurs that too much material in the leg can spark unwanted in-trouser rucking. "Which is why it's good to wear them at night. I prefer to wear the briefs during the day." The Beckham voice rises a semi-desperate semi-octave. "But everyone's different!" Remorselessly, we continue, contemplating a selection of thigh-fitting, boxer-meets-budgie-smuggler hybrids (the label says 'Trunk Briefs').
These come in two styles, one offering a buttoned fly, the other a supportive pouchy arrangement. This offers optimal comfort but – how to say it chastely? – reduced egress. "I probably prefer the pouch to the fly," Beckham says, "personally." A pause. Then he cracks. The brow ruefully crinkles, and sinks towards his hands. "What I just said! 'I prefer the pouch'!" Britain's pre-eminent sporting hero of our time adopts an own-goal slump. From behind her BlackBerry, his personal publicist Jo Milloy says via a sigh that she can see the headline now.
Ouch. Well. Now you know. The collection will be in stores on February 2, complete with a commercial that Beckham says will be a little scandalous.
"Seeing the video I thought, 'Millions of people are going to see this. And, it's, ummmm, me, on a turntable, spinning, in my underwear.'"
Well. We certainly don't have any qualms with that. Read the rest of Beckham's interview here.


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Family Day: Active Art
Sat, May 11, 2013, 11 am–3 pm
Experience Amalia Pica's participatory pieces and spend the day creating installations that activate all parts of the MCA.
Studio: Spinning Station with Annie Heckman
Let a spinning top guide you across the museum: spin it, and follow it.
Studio: Color Space with Kristin Sabatino
Design the walls of a shared structure using colors of all sorts.
Pop-up Dance Experience: Hubbard Street Youth Ensemble
Watch dancers respond to artwork with improvisational movements and then participate yourself.
Tot Spot
Kanter, 1st floor
Tot Spot is a great place to rest and recharge as a family. Enjoy a complementary healthy snack, build a structure, or read a book. Join us. All are welcome.
Find the Artist
Artist Alex Chitty is roaming throughout the galleries—find Alex and join her for a conversation or game.
Scavenger Hunt
Picture clues will lead to six artworks. Complete the search and stop by one of the registration tables to claim a prize.
Support for Family Programs is provided in part through the MCA Women's Board Family Education Initiative.
Snacks for Family Day are provided in part by KIND Healthy Snacks.


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A film 3 years in the making is certainly a film to watch. "Parabatix" invites you to join us on adventures to exotic locations from around the globe. It will take you to the edge of control and beyond. Through wind, rain, fire, sleet and snow, these pilots brave it all for the thrill of the experience and to capture footage! Wyat Drewes, Tim Koranda, Jason Peters, Jimmy Hall, Team Evolution, and countless others have teamed up to bring you the most diverse, passionate, and professional "skydiving DVD" in recent years.
Parabatix encompases mountain swoops, stunt/object swoops, B.A.S.E. jumping, Paragliding, World Record RW/Vertical formations, High Performance CReW & Formation Canopy Flight. Don't miss out on Jason Peters' amazing World Record Footage. See Wyat Drewes carve up the tallest sea cliffs in the world. Watch Jimmy Hall B.A.S.E. Europe and return to Hawaii to jump out of a helicopter with his paraglider.
Remember that crashes play a roll in a high risk sport where living on the edge is just the status quo. The WRECKS section of Parabatix will leave you in stitches!!!
Shipping Weight 1 lb (455g) NTSC & PAL.
Combine videos for quantity discount.


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Watch Berserk Movie 2 The Golden Age Arc II: The Capture of Doldrey
Genres: action, adventure, fantasy, supernatural
Plot Summary: This second Berserk film will cover the part of the series dealing with the taking of the important Band of the Hawk stronghold.
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Alternative Title:
Berserk Ougon Jidaihen II: Doldrey Kouryaku
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'A Journey of the Heart'
Last August, when this newspaper carried a story about the remarkable recovery of Eddie Justesen from a brain injury, we reported that his wife Lara was pregnant with their second child. It was a pregnancy that defied the odds, a one-in-a-hundred cha...
'No Grave Unadorned' succeeds again
With around 40,000 handmade flowers in their baskets, volunteers in Carbon and Emery counties achieved last week what no other communities in the nation do.
Sally Mauro will get a pre-school, but it will not happen this year
At the last regular session of the Carbon School Board it was discussed that with the change in the grade levels in the district (sixth grades will not be in middle school) Sally Mauro Elementary would have more room and that has been requested by ma...
Balloons for Brylee
Balloons float into the sky above Price last Wednesday evening, released by a crowd of people at the Dino Mine Park in memory of Brylee Olson. Brylee died May 20 of an inoperable brain tumor, just two days before her fourth birthday. The community ra...
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I did one of these guilty pleasure posts a few weeks ago, and I really enjoyed opening up to you (my readers) a little bit more. Of course I'm not one of those bloggers that exposes every aspect of my life, but I do make it a mission to express myself on any subject that I feel is worth being personally attached to. But when I'm not writing about serious social issues or my opinions on dates I go on (I have a date tomorrow lol,) then I like to let you guys get a sense of the quirky things that make me who I am.
So, let's talk about those guilty pleasures. I already admitted I have a huge passion for singing 80s and 90s love ballads, but I also have another passion of mine worth mentioning; I love Romanian dance music. I've never been over to Romania, but I first fell in love with their dance music in my freshmen year of high school. I attended four different high schools in a period of my 3 year early graduation track, but I briefly attended Washington & Lee High School in Arlington, Virgina.
I hated every moment of being at that school, mainly because all the girls that emotionally tormented me in middle school ended up going to the same high school. Remind you, I'm 6ft tall and could easily do some heavy damage if I wanted to, but it wasn't worth it. Instead I ended up chasing the girl down the hall, cussing her out, and putting a great fear in her. But I still had to face them everyday at that high school and I barely had any friends; it was a miserable time, but it was also a time in my life in which I found another guilty pleasure. Even in the midst of horrible times, I still always find a sense of peace.But for more on that story and how I detest bullying, watch my video vlogs here ———>ThinkSoul25 Discusses Bullying
So back to Romanian dance music. I first fell in love with it when I met this Romanian student in one of my science classes. Till this day I can't remember his name, but I remember he was one of the coolest kids I've ever met. A lot of the kids didn't talk to him and thought his accent was weird, but I loved how vibrant his personality was. Come to think of it, I slightly had a little crush on him. He was so rough and jagged on the edges, but I found it sexy in this exotic way; so I ended up spending every lunch break hanging out with him. We'd peruse around the school and then go to our science teacher's classroom to watch YouTube videos.
I learned some pretty neat things about Romanian culture from that guy, and I also learned that O-Zone was one of the coolest Romanian boy bands ever! Everyday at lunch my friend would sing me their song "Dragostea Din Tei," followed by a series of flirtatious laughs and hugs. At first I had no idea what he was talking about, but then he started showing me more Romanian music and the language. I don't know Romanian, but I know what it sounds like when it's being spoken. It's a pretty interesting language and their culture is fascinating, so if I could remember that guy's name then I would truly thank him for flirting with me, being my only true friend at that school, and showing me how awesome Romanian dance music is.
I may not know a lot of great Romanian dance music, but when I hear it I love it. The Romanian "sound" is one that is hard to miss. It has this pop vibe, but the beat always has some high pitched repetition that may be annoying to some, but I like it. If you've listened to Edward Maya and Vika Jigulina's "Stereo Love," and you liked it, then you will probably like a lot of other Romanian dance music. It's one of those things that is kind of a guilty pleasure. I didn't want to admit I love the sound and sometimes the cheesy factor, but I can't help it! That guy in high school really turned me on (interest wise, not physical) to the Romanian dance music and overall vibe.
Dance music is such a massive industry that has a variety of sounds, but the Romanian artists stand out amongst the masses. Their accents can easily be heard on every lyric and the beats stay true to that Romanian "sound." You might love it or you might hate it, but at least check out some Romanian music and give it a shot. Who knows, it could end up being a guilty pleasure for you as well. :)
Radio Killer – Lonely Heart TETA
Romanian "sound" takes over dance music scene
O-Zone – Dragostea Din Tei
Deepcentral – Cry It Away (Official Video)
Edward Maya & Vika Jigulina – Stereo Love (Official Music Video)
©Jasmine McGee.ThinkSoul25. http://thinksoul25.com


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U.S. Defense Secretary Panetta Makes Unannounced Visit to Afghanistan
Defense Secretary Leon Panetta looks at the 3rd Infantry Division... Fotografia de notíciasAeroporto,Aeroporto de Kandahar,Afeganistão,Chegada,Conflito,Diplomacia,EUA,Horizontal,Infantaria,Kandahar,Leon E. Panetta,Mascote,Olhar,Política,RochaPhotographer PoolCollection: Getty Images News 2012 Getty ImagesKANDAHAR, AFGHANISTAN - DECEMBER 13: U.S. Defense Secretary Leon Panetta looks at the 3rd Infantry Division mascot, Rocky the Bulldog, with Army Maj. Gen. Robert Abrams, (R) after Panetta arrived at Kandahar Airfield on December 13, 2013 Kandahar, Afghanistan. Secretary Panetta is meeting with Afghan president Hamid Karzai and top Afghan officials as the the U.S. look towards a desicion on troop numbers once the U.S. led coalition ends in late 2014. (Photo by Susan Walsh - Pool/Getty Images)