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Seniors Craft Shoppe on Facebook, YouTube
After more than 30 years in downtown Ventura, the Seniors Craft Shoppe is not only catching up with the times — with a Facebook page, YouTube video and a credit card machine — but also is at the cutting edge of many of today's most buzzed-about trends, including items crafted from recycled materials.
The shop is a cooperative of about 30 Ventura County residents 50 and older who make items to sell. "We are recycling ourselves. Most of us have made all the baby blankets and booties they can stand and the babies can handle," publicity chairwoman Roberta Bear of Port Hueneme said. "We're retired, and we want to have a new outlet."
Thousand Oaks resident Marian Anderson, the shop's past president, enjoys knitting and crocheting. She also casts china tea sets, using her own molds and kiln and painting and glazing the pieces.
"People are tired of imported things. This is all made in America," Anderson said. "We have people who come in here every year from England and buy the tea towels with the crocheted tops. They say they can't find things like that anywhere else."
The eclectic blend of items at the shop includes knitted and crocheted baby items, which Bear said are perfect purchases for people who want to give original treasures but don't do crafts themselves.
"Many of these are instant heirlooms, to be handed down," Bear said.
Crafters have long recycled materials to make new items, she said, pointing out girls' dresses decorated with old embroidered handkerchiefs. Another artist uses old barn wood as her canvas.
The Seniors Craft Shoppe, 429 E. Main St. in Ventura, is open 10 a.m. to 5 p.m. Mondays through Saturdays and 11 a.m. to 4 p.m. Sundays. The phone number is 643-3059. Visit the shop's Facebook page for photos and more information. You can also take a virtual tour of the shop on YouTube. Click the link on the Facebook page, or go to http://www.youtube.com and search for "Seniors Craft Shoppe downtown Ventura."
Some people shred plastic bags to create "yarn" that they crochet into such items as soda bottle holders, hats and purses.
Bear said members are just getting started with the Facebook page, which has photos and a link to the YouTube video made by VenturaCountyNow.com, the online business directory. "We don't have the resources to have our own Web page," Bear said.
The small shop is crammed full of unique items.
"I tell people to look up and down and all around and keep looking until you find something you couldn't live without," Bear said. "Our prices are competitive. We're less expensive than a boutique."
People interested in joining the cooperative must submit a craft sample to the board of the nonprofit.
There is a training and probationary period, and members must commit to working at least half a day per week at the shop. The profits are split between members and the store to cover overhead and expenses.
Ann Schlesinger of Ventura, Seniors Craft Shoppe president, said she and the other members of the cooperative have enjoyed watching downtown Ventura grow, especially during the past few years.
"It's been nicely updated. There is good and bad, but there are wonderful new shops and businesses, while still letting people get a taste of small-town America," she said.
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Items where Author is "Quintane, Eric"
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Conaldi, Guido, Quintane, Eric, Lomi, Alessandro and Tonellato, Marco (2012) Modeling relational events: a case study on an open source software development project. In: American Sociological Association Annual Meeting 2012, 17-20 Aug 2012, Colorado Convention Center and Hyatt Regency, Denver, CO, USA. (Unpublished)
Quintane, Eric, Tonellato, Marco, Conaldi, Guido and Lomi, Alessandro (2012) Modeling relational events: a case study on an open source software development project. In: Academy of Management 2012 Annual Meeting: The Informal Economy, 3-7 Aug 2012, Boston, MA, USA. (Unpublished)
Tonellato, Marco, Conaldi, Guido, Quintane, Eric and Lomi, Alessandro (2011) Specification and Estimation of a relational event model for 2-Mode networks: an application to organisational problem-solving. In: XXXI International Sunbelt Social Network Conference, 08-13 February, 2011, St. Pete Beach, FL, USA. (Unpublished)

subset: commoncrawl


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Western Storm to put faith in running game in cut-throat TSL first semi-final
- From: Mercury
- September 06, 2014
IT'S hard to prepare for a final against a team you've played only twice in the past two years but Western Storm coach Mitch Hills believes he has nailed it.
Coming off back-to-back losses, both to North Launceston, Hills has used video of Lauderdale's elimination final win over Glenorchy to prepare Western Storm for today's cut-throat TSL first semi-final at Aurora Stadium.
Lauderdale goes in with a sparkling record of nine wins from their past 10 games, making the Bombers a huge threat.
Both coaches admit to limited knowledge of their opponents.
Hills said that made game footage invaluable.
"We looked at how they play and who played well against Glenorchy, and we've worked out a plan for this week and where we think we can expose them," Hills said.
"We've been talking about that since Monday night."
The hard-running Storm and hard-hitting Bombers have different game styles. Hills says Storms' will suit Aurora better than Lauderdale's.
"The advantage we've got is playing at Aurora Stadium," he said.
"It's a really big ground and this is our fifth week in a row playing there, so if we can't get it right this week we are probably never going to.
"We feel this ground suits our game style, probably not their's, but having said that it's a final and they are going to be coming after us very hard."
Lauderdale's newly-crowned TSL rookie of the year Ben Halton will be put under the pump by Storm full-back Tom Reinmuth, but Bombers coach Darren Winter's attention will be on Storm's stars, particularly the TSL's fourth-highest goalkicker and former Brisbane Lion Bart McCulloch.
"I've watched their past few games and they're obviously a very good unit and there's a few young blokes I didn't know a great deal about," Winter said.
"We're more concerned about their top premiership players from last year, they are the ones we will focus on — Jay Blackberry, Matt Hanson, Mitch Hills, Bart McCulloch.
"We'll do a few good match-ups on those guys and try to shut them down."
As for their chances on the big, flat AFL ground, Winter says the Bombers will give a good account of themselves.
"They [Storm] play the ball really wide around the boundary and then get it back through the middle of the ground, and we like to play contested footy, in close and tight," Winter said.
"We have to be able to match their run on the outside and we'll try to close the game down even though it's a lot harder to do on a big ground."
Lauderdale has never progressed further than a TSL first-semi, but Winter said the team was confident they can continue their good form.


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Blessed Mariano de la Mata Aparicio
One of eight children born to Martina and Manuel de la Mata Aparicio. Studied in Valladolid, Spain. Joined the Augustinians on 9 September 1921, taking his solemn vows on 23 January 1927. Studied in Pisuerga, Spain and then at the monastery of Saint Maria La Vid in Burgos, Spain. Ordained on 25 July 1930. Taught at the College La Encarnación in Llanes, Spain. Missionary to Brazil in July 1931. He became known as the messenger of charity to the poorest of the poor. Teacher and coordinator of teaching throughout the missionary region.
- 31 December 1905 in La Puebla de Valdavia, Palencia, Spain
- 20 December 2004 by Pope John Paul II (decree of heroic virtues)
- 5 November 2006 by Pope Benedict XVI
- recognition celebrated at the cathedral in São Paulo, Brazil
- "Blessed Mariano de la Mata Aparicio". CatholicSaints.Info. 4 June 2015. Web. 7 October 2015. <>


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Roger Taylor
Birth Name: Roger Taylor
Born: 12/26/1949
Birth Place: Norfolk, England, GB
Born: 12/26/1949
Birth Place: Norfolk, England, GB
Born July 26, 1949 in King's Lynn, a seaport town in Norfolk county, England, Roger Meddows Taylor was raised in Truro, a city in the southwest of England, by his parents, Michael and Winifred. He began performing in bands while still very young, playing ukulele with friends in a group called the Bubblingover Boys at the age of seven. After teaching himself to play guitar and drums, Taylor turned semi-professional at the age of 13, playing with several fellow students from Truro Cathedral School in a band called The Reaction. He briefly put his music career on hold in 1967 to study dentistry at the London Hospital Medical College, but by the following year, was playing in a new group, Smile,... Continue Bio >>
Popular Movies and Television:
We Will Rock You
2001 2001: The Power of Music
2001 2001: The Year in Music
1991 Concert For Life
1990 Queen: The Days of Our Lives


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Paloma is a two star mid-priced business and tourist hotel located in the heart of the city located on a...
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What causes increase in blood pressure and low blood pressure? 5 possible conditions
See a list of possible causes in order from the most common to the least.
Congestive heart failure is a chronic condition that affects the four chambers of the heart. Early symptoms include fatigue and weight gain. Irregular heart beat and wheezing indicate a worsening.
This condition is considered a medical emergency. Urgent care may be required.
A clot blocks the blood flow to the heart (heart attack), and damages heart muscle. Symptoms include chest pain, shortness of breath, and a blue or grey tinge to the skin.
This condition is considered a medical emergency. Urgent care may be required.
An overdose happens when you take too much of a drug. Whether intentional or accidental, drug overdoses can be life threatening. Adrenergic bronchodilators overdose is when a person has taken too much of a certain typ...
Autonomic neuropathy is a condition that results from damage to nerves that help organ and organ systems function. It's often a complication associated with other medical conditions, diseases, and certain medications.
This condition is considered a medical emergency. Urgent care may be required.
A spinal cord injury, or damage to the spinal cord, is an extremely serious type of physical trauma. It will likely have a lasting and significant impact on most aspects of daily life. According to the Nationa...
Please consult a healthcare professional if you have health concerns.
Click to add a symptom to your list
- Top Symptoms
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by Alison Zavos in New Photography on Thursday 19 November 2009
Paris-based Amelie Lombard is an advertising photographer specializing in food and still life. These photos are from the series, Aphrodisiaques.
Austin-based Alison is the founder and editor of photography blog, Feature Shoot. She's just discovered blue cheese with honey and she is in love.
See more from Alison Zavos
Share your favourite cultural finds with the Lost At E Minor community and become famous in the process. Well, kinda.
by Rachel Oakley
by Nicole Hughes
by Inigo del Castillo
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The Rally to Restore Sanity: A Call for the Media to Look Inward. ~ Jax Jackson
"If we amplify everything we hear nothing." — Jon Stewart
Last weekend I went to a rally hosted by two television comedians. So did over 200,000 other people. What made my being there odd, however, is that I have not had cable television service for two years.
I still own a television and watch DVD's on it, but the rest of my media I get from the Internet. Even that is limited exclusively to 30-Rock, The Daily Show, and a little Colbert Report. Truly, those three shows are the only ones I watch. My reason for ditching the cable wasn't some self-righteous holier-than-thou anti-TV sentiment (I actually enjoyed hours upon hours of trashy talk shows and demeaning reality programming). I just really couldn't afford cable TV at the moment.
So you can imagine my excitement when I recently stayed in a luxury hotel room, complete with terrycloth robes and, yes, CABLE! I immediately hopped on the bed and flipped on the tube, leaning back on the bleached sheets to bask in the mothering glow of American culture.
But the light was harsh: When I had access to TV all the time I didn't realize that commercials are more and more manipulative and multiplying, like rabbits in spring. I flipped through a few channels to see if I could find programs that weren't directed at making me feel extremes. I decided that I would surely be safe from this Zen-less endless stream of manipulation if I just watched the news. After just a few minutes I realized something: the same conflict viewers seek in reality drama, they also seek from their news programs. CNN, MSNBC, FOX News, and other sources directly profit from creating mountains out of molehills, and Armageddon-esque androids out of mountains. They work hard to make you feel that some major event is just minutes away and if you turn the channel… you'll miss it!
I realized, in that hotel room, that I would probably never watch television again. Having separated myself from its daily barrage for so long, my system was more sensitive, more aware, and I could see with greater clarity what was invisible without stepping back.
I found at Jon Stewart's Rally to Restore Sanity and/or Fear others who shared my disgust, including Stewart. Sure, The Daily Show directly profits from conflict, but not in the sense that opinion and news shows do. News channels now use hyperbole, charged language, unscientific polling, and represent opinion shows as 'news.' They take the most dramatic extremes, put them side by side, and ring the bell for round one. As Stewart said, "The press can hold its magnifying up to our problems bringing them into focus, illuminating issues heretofore unseen or they can use that magnifying glass to light ants on fire and then perhaps host a week of shows on the sudden, unexpected dangerous flaming ant epidemic." Compromise, moderation, and empathy don't make for profitable television.
Stewart's profits, in comparison, come from parodying hyperbole. He counts on his viewers' desire to see through tactics news channels use to manipulate. So for him to step back and say to the 200,000+ people on the National Mall on October 30th, in essence, the press has got a job bigger than profit, was a powerful thing. It was the first step (in what I hope is a series of steps) towards greater responsibility and accountability in the press. They are, after all, specifically named in the constitution as an important democratic institution. Their health is tied to the health of our democracy.
Perhaps Stewart's greatest point, however, was that the picture of America that sells soap or gold or beer, isn't even true. He used the metaphor of cars merging into a tunnel one by one, allowing their fellow traveler the space to go and then taking their turn. He reminded us that this daily and simple co-operation (often happening without a thought) is who we really are. Stewart closed in the way only he can, linking the seriousness of his purpose with the humor that helps us see its truth, "We know instinctively as a people that if we are to get through the darkness and back into the light we have to work together. And the truth is, there will always be darkness. And sometimes the light at the end of the tunnel isn't the promised land. Sometimes it's just New Jersey."
Watch Jon Stewart's closing speech here.
(With editorial help from Scott Illingworth)
Jax Jackson is an actor, activist, and active resident of New York City. Scott Illingwoth is a theatre educator, freelance director, and movement teacher in New York City.
Incorrect source, offensive, or found a typo? Email us (please put title in subject bar of email so we'll be able to fix). Or do you want to write for Elephant?
{Waylon H. Lewis C Enterprises 2015: Use Rights in perpetuity. Ownership remains with author.}
4 Responses to "The Rally to Restore Sanity: A Call for the Media to Look Inward. ~ Jax Jackson"
Great points, Jax! I found Stewart's closing speech incredibly powerful and timely. Thanks for this account.
While Mr. Stewart makes some good (and also obvious to the extreme) points not only about corporate news media but about the true nature of American society at a grass-roots level, the only cause he calls upon anyone to espouse is an afternoon's entertainment on the National Mall described to me by one trusted attendee as a weed-fest to put Deadheads to shame. Not that there's anything wrong with that! How it advances the cause of accountability in the press escapes me.
I gained a great deal more hope and encouragement from Jax's article than I did from the rally. The paradox of a writer who's sworn off over-the-top TV championing a rally for an over-the-top TV star is strangely inspiring. That writer's call for "compromise, moderation and empathy" is what this is all about. It's also what we're not going to get as long as ratings determine profits. And we're not going to change that dynamic even if we rally til we run out of weed.
I was at the rally and I can say all people in attendance were civil. Nobody started any fights with anyone. It was a calm Saturday to hang out and listen to a good show. Like John Stewarts says, Every damn day we all work together and for some reason the media never focuses on that… .www.adrianagallegos.com
[…] turned out to be one of the sanest voices for political moderation, as demonstrated by his recent Rally to Restore Sanity. Check out some of his work here, here, and of course […]


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Go with the
flow in this vest that instantly transforms an outfit into something special.
Designer Sarah Kay Hartmann
Finished Size Center halter opening circumference stretches to
fit 50 (60)" (see Notes).
Yarn Zitron Kimono (distributed by Skacel) (54%
merino, 46% silk; 328 yd [300 m]/3.5 oz [100 g]): #4005 royal purple, 4
Hook Size G/6 (4 mm). Adjust hook size if necessary to
obtain correct gauge.
Notions St marker (m); yarn needle.
Gauge 21 sts and 24 rows = 4" in seed st patt
after blocking.
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Gogol Bordello is a band, not a person. But yeah, that's not Eugene Hutz.
I'm pretty sure she has all those things, but that still is probably not her....
I wasn't looking that close... glad someone took a closer inspection though lol
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Originally posted by silo13
No, I don't have a weak stomach, I don't know that my reaction is even a weakness, but, whatever it is, the sound touches something in my soul and makes it hurts.
Originally posted by Starbug3MY
The police have never been anything but nice and polite to me. They have gone out of their way to assist me and I have never thought about not going to the police for help.
Has anyone seen the film called A (or The) Thin Blue Line?
[edit on 1-8-2010 by Starbug3MY]


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MacPhantom wrote:I know the sympathies of a stranger can't help but be useless; nonetheless, I'm still very sorry for your loss.
MacPhantom wrote:Odd that you would describe your painting as feeling "warm and good", considering that blues and greens are generally considered cool colors. Green that has more yellow in it could be considered warmish, depending on the context, but in your painting the green that is present is dominated by blue, a definite pull towards the colder end of the spectrum. The light emanating from the center could also be seen as warming, except the light is whitish, again tinged with blue, and feels cold, like the light from a deep refrigerator, or a lantern submerged in a lake.
There appear to be beams of light emanating outward from the center with a natural regularity, but they are disturbed by two rather harsh lines running somewhat vertically, but without the comforting order brought by being parallel, and they themselves are bisected by a third line running roughly horizontally, but again, with a jarring lack of predictability.
Then there are the rings, which remind me of imprints burned onto the retinas by an overly bright light, an unpleasant experience which makes the light in your painting seem not comforting, but harsh and confrontational. The light at the center is not inviting. It isn't somewhere I want to be, but the alternative, outside the light, is a scarier option; dark shapes haunt the corners and edges of the painting.
The Japanese characters say to me "confusion"; the confusion of an unknown language. Who left the message? What does it say? You say it means spirit, but is that reverential or ominous?
I'm with Nevermore. That is a spooky painting.
What is your picture of, Corvus? It appears to be some sort of glass, but it reminds me of the birth canal. It also has a floral aspect to it.... but then, those two ideas are traditionally linked in art, aren't they....
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Static-X -- Wantagh, NY -- April 21st, 2009
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Join Date: Apr 2009
Location: Fresh Meadows
Posts: 70
Static-X -- Wantagh, NY -- April 21st, 2009
SnoCore Tour, although I wasn't a fan of the other bands on the bill, but Static-X always puts on a good show and puts out good music. Saliva dropped off the bill, which was fucking awesome. I guess Josey Scott got gonhorrea of the throat from sucking Chad Kroeger's dick on a rooftop somewhere. The Flood wasn't great onstage, but the music is decent. I guess no one told them it wasn't cool to wear white contacts, act epileptic, and rock back and forth like you're nuts. The guitarist didn't move from the 11th fret all night and he wore a black Hot Topic trench coat and had black eye and hand make-up. They were just very...2001...lol. Burn Halo blows a bigger dick than Saliva sucks. They all look 14 and are questionably female. They may have the potential to be a good rock and roll band if they dropped the image, the bassist, and the singer. Static-X was fucking sick, they transfer very well live. Yes, I know, a lot of their music sounds the same, but Wayne and the boys picked a perfect blend of songs to make everyone happy. They played songs from all of their albums, and kept it rocking the whole entire time. He had is smokin' hot wife handing them shots after every 3 songs. I couldn't have thought or asked for a better setlist, except for maybe "Get to the Gone." My girl gave me a pick from Tony that she found.
Onto the sets. I don't know the names of The Flood or Burn Halo's songs, so I just kinda wrote down what they repeated over and over.
The Flood
1. Beatboxing Intro
2. In My Veins (?)
3. Something about a "Faerie"
4. Only Here to Love You (?)
5. Time
6. Save Me
7. The Flood
Burn Halo
1. Face in the Mirror (?)
2. So Addicted
3. Dead End
4. Our House
5. Gasoline
6. Dirty Little Girls
7. Save Me
1. Lunatic
2. Dirthouse
3. I'm With Stupid
4. Down
5. Stem
6. Black and White
7. Stingwray
8. Destroyer
9. Cold
10. Bled For Days
11. Behemoth
13. Destroy All
14. Cannibal
15. Love Dump
16. This is Not
17. Push It
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What Are You Thankful For?
On the fourth day of our babymoon, we had a lazy family day. Aside from Ailia's first trip to the chiropractor (and my first post-partum adjustment, which I think was as wonderful – if not more so – than my prenatal adjustments), we sat around the house and did fun, relaxing activities.
At one point, Tom and I were both on our computers and Kieran was listening to audio books on the tablet. He randomly selected a book to listen to about the "history" behind Thanksgiving – complete with pilgrims, Native Americans, etc. I wasn't paying much attention until I heard the book wrapping up. The narrator talked about what the pilgrims were thankful for – friends, food, and shelter.
And then the narrator asked, "what are you thankful for?"
Kieran's response:
Yes, I cried.1
- Kieran's response was all the sweeter because he has only recently begun really enunciating his "L" sounds (they used to sound more like "W" sounds). And when he makes the "L" sound, he sticks his tongue out just the tiniest bit, so it makes the L that much more prominent (this used to be a very conscious move he did to make the sound, now he does it more subconsciously). He does it with Ailia's name too, I love hearing him say her name! ↩
10 Responses to:
"What Are You Thankful For?"
I'm pretty sure I would have cried, too. You seem to have done a beautiful job of wrapping your little family in love :)
I love this so much!!
Baby's first chiropractic! Love that too.
Lucky kids.
Awwww… that was so so so sweet!
Awwww that's so sweet
Well it made ME cry too…such a sweet boy you have!! I am blessed to be able to call him Grandson!!! He is just ONE of the many things….or should I say PEOPLE that I am thankful to have in my life!!!
Yes, so very sweet. Eyes glistening… :)
Aww, sweetest thing ever!
Oh my goodness that is sweet. I just had my son a month ago (!)and totally have been having those melt your heart moments. I also got my son (and whole family) to the chiropractor because I needed an adjustment postpartum and helpful to get the children adjusted early, I think. A funny truth — both births, I went into labor the day after getting adjusted. I told my chiropractor that he should start advertising!
Yay for babymoon!
Aw, so sweet!
My 3-year-old recently said, "I like my family, because they are my people." I admit to totally melting at that one.
So very, very sweet!
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The Message Board for Pet Chicken People
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I am hatching some quail and was wondering if i could just keep them in the coop with the chickens? What do you think? All i need to do is put in a little feeder and waterer. Maybe give them something to hide in. What do you think? These are white coturnix quail im talking.
They are fine with bantams but standard chickens might be ify. IF your chickens are docile and the quail are at least 9 weeks... you might be ok. Seriously... Mine freerange with a bunny but it doesn't eat meat! lol Maybe putting a cage on the floor in the coop for them to get use to one another first... and you can get a feel for how the chickens are going to react. Remember that full grown they are about half the size of a bantam.
Well it might work. There is a hiding place behind the feed bin.
collecting eggs will be hard if they are always hiding.
I really think giving them time to get to know eachother before putting them together should work.
I would not keep them together. The chickens will kill the quail, bantam or not. Quail are SUPER tiny also, so it's very possible they would get lost! I know they can fit right through chicken wire. Also, quail typically do not perch, so the chickens may squish them when they jump off their perches!
However, it wouldn't be too expensive to build anything. A nice large hutch would work fine! That way you can still let your chickens free range AND you can breed the quail without a problem!
I would love to get some quail, but I'm not sure where I would put them. They sure are cute as babies though! Good luck!
Brooster--great question, I'm wondering about it too.
My chickens don't bother the sparrows and wrens, do you think they would leave the quail alone? I've seen both chickens and sparrows/wrens scratching in the yard almost side-by-side.
What kind of housing/runs do you use for quails?
Just so you don't think I am nut I am looking at getting a Japanese bantam hen in a few months to incubate for me...
The best is the Bantam (Japanese chicken or short legged chicken). The method is simply to replace the Bantams eggs with the fertilized quail eggs. To start, first set the nest for the Bantam to lay its eggs. When the eggs are laid, after 3 days, replace the Bantams with the quail eggs.
There is no problem with these jumbo quail and bantams as long as the bantams are docile.


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IANSA members at MGE2: 1-5 June 2015
2 June 2015 is National Gun Violence Awareness Day! Click on the image to join the campaign.
Global Week of Action Against Gun Violence 2015
This year's Global Week of Action Against Gun Violence is scheduled for 11-18 May 2015.
For all information on MGE2 held 1-5 June 2015, please visit our MGE2 page at: www.iansa.org/MGE2
The Security Council open debate on "The human cost of the illicit transfer, accumulation, diversion and misuse of small arms and light weapons"(SALW) took place at the UN in New York on 13 May.
This year's Global Week of Action Against Gun Violence takes place from 11-18 May.
This is important information for NGOs on the second Open-ended Meeting of Governmental Experts of the Programme of Action to Prevent, Combat, and Eradicate the Illicit Trade in Small Arms and Light Weapons and All Its Aspects.
Please find attached a link for the Aide Memoire for Non-Governmental Organizations for MGE2 in June 2015.
The Women International League for Peace and Freedom launched the 2010-2020 African Women decade on the 31st July in London.
IANSA women in Nigeria, the Women's Right to Education Programme held a Training of Trainers' workshop on 'Conflict Transformation, Peace Building and Small Arms Control' on 22-23 July.
PIRCenter, The Russian Center for Policy Studies held their 10th annual International Summer School from June 20 - July 3, 2010.
The Global Youth Network of Religions for Peace is advancing a United Nations General Assembly (UNGA) resolution that asks member states to cut military spending by 10% and redirect those funds toward achievement of the UN Millennium Development Goals (MDGs).
Pressure by individuals and organisations may provide the tipping point when arms exporting democracies weigh up their concerns about national interest versus human rights criteria, concludes Guy Lamb of Institute for Security Studies in the new article "South African Arms Exports: A Balancing Act".
IANSA is a global voluntary network of organisations working to stop gun violence - including policy organisations, gun control groups, women's groups, research institutes, aid agencies, faith groups, health workers, survivors, human rights and community action organisations. More


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Selected Alumni Publications
Jennifer M. Ross-Nazzal (Ph.D. '04) has published Winning the West for Women: The Life of Suffragist Emma DeVoe through the University of Washington Press. Article
Michael Egan (Ph.D. '04) and Jeffrey Crane (Ph.D.04) have co-edited a volume of essays on the history of American environmentalism. In late 2008, Routledge published "Natural Protest: Essays on the History of American Environmentalism."
James Ross-Nazzal (Ph.D. '01) has published The U.S. Veto and the Polemics of the Question of Palestine in the United Nations Security Council, 1972–2007 with Edwin Mellen Press.
Jeffrey A. Johnson's (M.A.'00, Ph.D. '04) book "They Are All Red Out Here: Socialist Politics in the Pacific Northwest, 1895-1925" was published by University of Oklahoma Press.
Andrew Duffin's (Ph.D. '03) book Plowed Under: Agriculture and Environment in the Palouse was published by University of Washington Press.
James Lester's (Ph.D. '75) book Public Policy: An Evolutionary Approach was published by Wadsworth Publishing.
Michael Egan's (Ph.D. '04) book Barry Commoner and the Science of Survival: The Remaking of American Environmentalism was published by MIT Press.
Matthew Godfrey's (Ph.D. '01) book Religion, Politics, and Sugar: The Mormon Church, the Federal Government, and the Utah–Idaho Sugar Company, 1907–1921 was published by Utah State University Press. It won the Mormon History Association's Best New Book award for 2007.
Jean Johnson's (Ph.D. '95) article "Hidden Treasure: Kah-Nee-Ta" was published in Smithsonian's National Museum of the American Indian magazine.
Kevin Marsh's (Ph.D. '02) book Drawing Lines in the Forest: Creating Wilderness Areas in the Pacific Northwest was published by the University of Washington Press in its series Weyerhaeuser Environmental Books.
Kenton Bird's (Ph.D. '99) book Reporting That Matters: Public Affairs Coverage was published by Allyn & Bacon, Inc.
Jean Eder's (Ph.D. '00) book American Indian Education: A History was published by University of Oklahoma Press.
Patricia Hart's (Ph.D 97) book Women Writing Women: The Frontiers Reader was published by University of Nebraska Press.
Jason Knirck's (Ph.D '00) Imagining Ireland's Independence: The Debates over the Anglo-Irish Treaty of 1921 was published by Rowman & LIttlefield Publishers, Inc.
Michael P. Malone's (Ph.D. '66) book The Battle for Butte: Mining and Politics on the Northern Frontier, 1864–1906 was published by University of Washington Press.
Katherine Aiken (Ph.D. '80) published Idaho's Bunker Hill: The Rise and Fall of a Great Mining Company with the University of Oklahoma Press.
Laurie Carlson's (Ph.D. '04) book William J. Spillman and the Birth of Agricultural Economics was published by University of Missouri Press.
Jerry Garcia's (Ph.D '99) book Memory, Community, and Activism: Mexican Migration and Labor in the Pacific Northwest was published by Michigan State University Press.
Brenda Jackson's (Ph.D '05) book Domesticating the West: The Re-creation of the Nineteenth-Century American Middle Class (Women in the West) was published by University of Nebraska Press.
Johnson Ringsmuth's (Ph.D '01) book Snug Harbor Cannery: A Beacon on the Forgotten Shore 1919-1980 was publshed by the National Park Service.
Sara Ewert's (Ph.D '00) The Encyclopedia of National Parks was published by New York, M.E. Sharpe.
John Mann's (Ph.D '01) book Sacajawea's People: The Lemhi Shoshones and the Salmon River Country was published by University of Nebraska Press.
F.W. Blackwell (M.A. '60), Kathryn Meyer (M.A. '82, Ph.D. '92), and Mary Watrous (Ph.D., '91) published Global Passages, a 2-volume reader in world history (Houghton-Mifflin, 2003).
Neil O'Brien's (Ph.D., '01) American Editor in Early Revolutionary China: John William Powell and the China Weekly was published in the Monthly Review (New York, N.Y.).
Peter Utgaard's (Ph.D., '97) book Remembering & Forgetting Nazism: Education, National Identity, and the Victim Myth in Postwar Austria was published by Berghahn Books.
The Anchorage National Park Service published Geoffrey Bleakley (Ph.D. '96) Contested Ground: An Administrative History of Wrangell.
Laurie Winn Carlson (Ph.D. '04) published Cattle: An Informal History with Ivan R. Dee, Publisher.
Buried Dreams: The Rise and Fall of a Clam Cannery on the Katmai Coast by Katherine Johnson (Ph.D. '05) was published by the United States Department of the Interior National Park Service.
Charles V. Mutschler's (Ph.D. '99) book Wired for Success: The Butte, Anaconda, & Pacific Railway, 1892–1985 was published by Washington State University.
Deb Sutphen's (Ph.D. '97) book Standing Guard: Telling Our Stories is a collaborative work on Japanese Americans in the Grass Valley, California was published by Sierra College Press.
Bob Hadlow (M.A. '87, Ph.D. '93) published Elegant Arches, Soaring Spans: C.B. McCullough, Oregon's Master Bridge Builder. The book was published by Oregon State University Press.
Greg Hall's (M.A. '94, Ph.D. '99) book Harvest Wobblies: The Industrial Workers of the World and Agricultural Laborers in the American West, 1905–1930 was published by Oregon State University Press.
Diane Krahe's (Ph.D. '05) book A Sovereign Prescription for Preservation: The Mission Mountains Tribal Wilderness was published by University of Colorado Press.
Keith Petersen's (Ph.D. '73) River of Life, Channel of Death: Fish and Dams on the Lower Snake was reissued by Oregon State University Press.
Laurie Winn Carlson's (Ph.D. '04) book A Fever in Salem was published by Ivan R. Dee, Publisher.
Michael P. Malone's (Ph.D. '66) book Montana Century was published by TwoDot; First Edition.
Katherine Aiken's (Ph.D. '80) book Harnessing the Power of Motherhood: The National Florence Crittenton Mission, 1883–1925was published by University of Tennessee Press.
Steven A. Leibo's (Ph.D. '82) book East, Southeast Asia, and the Western Pacific 1998 was published by Stryker-Post Publications.
Janet M. Manson's (Ph.D. '87) book Women in the Milieu of Leonard and Virginia Woolf: Peace, Politics, and Education was published by University Publishing Association.
Samuel Regalado's (M.A. '83, Ph.D. '87) book Viva Baseball! Latin Major Leaguers and Their Special Hunger was published by University of Illinois Press.
Peng Deng's (Ph.D. '90) book Private Education in Modern China: China's Crisis and Revolution through American Lenses 1944–1949 was published by Praeger Publishers.
Sandra Haarsager's (Ph.D. '90, American studies) book Organized Womanhood: Cultural Politics in the Pacific Northwest, 1840–1920 was published by University of Oklahoma Press.
Erika Kuhlman's (Ph.D. '95, American studies) book Petticoats and White Feathers: Gender Conformity, Race, the Progressive Peace Movement, and the Debate over War, 1895–1919 was published by Greenwood Press.
Michael P. Malone's (Ph.D. '66) book James J. Hill: Empire Builder of the Northwest (Oklahoma Western Biographies, vol.12) was published by University of Oklahoma Press.
Peter H. Buckingham (M.A. '76, Ph.D. '80) published Rebel Against Injustice: The Life of Frank P. O'Hare (University of Missouri Press, 1996).
Voice of the Old Wolf: Lucullus Virgil McWhorter and the Nez Perce Indians was published by Steven Ross Evans (M.A. '69, Ph.D. '91) via Washington State University.
Michael P. Malone's (Ph.D. '66) book Montana: A Contemporary Profile was published by Farcountry Press.
Good-bye Piccadilly: British War Brides in America was published by Jenel Virden (B.A. '80, general studies; M.A. '83) via University of Illinois Press.
Stanley K. Hornbeck and the Open Door Policy, 1919–1937 was written by Shi-Zhang Hu (M.A. '87, Ph.D. '92), with Michael Polley (M.A. '78, Ph.D. '84), Jody Peterson (Ph.D. '98), and Noriko Kawamura listed as contributors. The book was published by Greenwood Press.
Breve historia de la sequía en México, written by Enrique Florescano and Susan Swan (Ph.D. '77), was published in 1995 by the University of Vera Cruz Press, Mexico.
Peng Deng (Ph.D. '90) co-authored with Jie Chen China Since the Cultural Revolution: From Totalitarianism to Authoritarianism. The book was published by Praeger Publishers.
Sandra Haarsager (Ph.D. '90, American studies) published Bertha Knight Landes of Seattle: Big-City Mayor (University of Oklahoma Press, 1994).
Michael P. Malone's (Ph.D. '66) book Montana: A History of Two Centuries was published by University of Washington Press.
Janet M. Manson's (Ph.D. '87) book Diplomatic Ramifications of Unrestricted Submarine Warfare, 1939–1941 was published by Greenwood Press.
Marv G. Slind (M.A. '72, Ph.D. '78) and Fred C. Bohm's (M.A. '73, Ph.D. '78) book Norse to the Palouse: Sagas of the Selbu Norwegians was published by Norlys Press.
The Diplomacy of the Sino–French War (1883–1885): Global Complications of an Undeclared War was published by Lewis M. Chere (Ph.D. '78), vol. III of The West and the Wider World series. The book was published by Cross Cultural Publications.
Edith E. Erickson (B.A. '60, education) and Eddy Chiu-Kuen Ng (B.A. '76, Asian studies; M.A. '79) published From Sojourner to Citizen: Chinese of the Inland Empire. This book was self-published.
Going to Washington State: A Century of Student Life was published by William Stimson (M.A. '89, Ph.D. '99). The book was published by Washington State University.
Peter H. Buckingham's (M.A. '76, Ph.D. '80) book America Sees Red: Anti-Communism in America, 1870s–1980s was published by Regina Books.
Keith Petersen's (Ph.D. '73) Company Town: Potlatch, Idaho, and the Potlatch Timber Industry won an award from the State and Local History Association. The book was published by Washington State University.
Gary Huey's (Ph.D. '81) book Rebel with a Cause: P.D. East, Southern Liberalism, and the Civil Rights Movement, 1953–1971 was published by Scholarly Resources.
Steven A. Leibo (Ph.D. '82) edited A Journal of the Chinese Civil War 1864 by Prosper Giquel and Transferring Technology to China: Prosper Giquel and the Self-strengthening Movement, published by the Institute of East Asian Studies, University of California, Berkeley.
Robert R. Swartout Jr. (Ph.D. '78) and Fred C. Bohm (M.A. '73, Ph.D. '78) edited and wrote the introduction to Naval Surgeon in Yi Korea: The Journal of George W. Woods, published by the Institute of East Asian Studies, University of California, Berkeley.
Peter H. Buckingham (M.A. '76, Ph.D. '80) published International Normalcy: The Open Door Peace with the Former Central Power, 1921–29. The book was published by Scholarly Resources.
Robert R. Swartout Jr. (Ph.D. '78) edited Montana Vistas: Selected Historical Essays by University Press of America.
Thomas J. Noer's (M.A. '68) book Briton, Boer, and Yankee: The United States and South Africa 1870–1914 was published by Kent State University Press.
Richard Dean Burns and Edward M. Bennett edited Diplomats in Crisis: United State–Chinese–Japanese Relations, 1919–1941. The book was published by ABC-Clio.
Michael P. Malone's (Ph.D. '66) book C. Ben Ross and the New Deal in Idaho was published by University of Washington Press.


text: Home » 1940s » In the doghouse, again? » 1942 957 1942 957 Time and again February 5, 2012 0 comments Share This Content Tweet Pin It • Meet the Author • Time and again I like to make things. It makes me happy. View My Website Love what you've seen so far? Subscribe by email to receive all the week's posts delivered to your inbox in one big glorious email every Friday. Inbox overflowing? Follow us on Bloglovin instead! Find the WeSewRetro crew chatting on Facebook and sharing pretties on Pinterest. 0 comments… add one Don't Be Shy » Leave a Comment! Cancel


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Married couple and business partners Mark and Hanna Lim came up with the idea of the Lollacup when their pediatrician recommended a straw cup for their 9-month old daughter. Unable to find one that worked, the couple created their own.
The couple made a deal with Robert Herjavec and Mark Cuban for $100,000 for 40 percent. According to the Lims, before they appeared on the show they had 50 accounts. Now, they sell to more than 650 accounts. The Lollacup is made in the USA, which the Lims felt was extremely important.
However, this "Shark Tank" success story almost never happened. The Lims originally were chosen as an alternative for "Shark Tank." Find out the details below.


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David Aubrey
Jade Dangle Drop Earrings
$69 Gilt
- Color:
- peach multi
Qty: 1
- 1
- 2
- 3
Please select an available size.
Please select a size.
Description: 18K yellow gold plated brass and simulated jade dangle earrings with green agate or peach glass cabochon drop details
- 4 inches long
- 1¼ inches at widest point
- Fishhook closure
Material: 18K yellow gold plated brass, simulated jade, agate, and glass
Brand: David Aubrey
Origin: United States


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The Mission of Miami Dade College is to change lives through the opportunity of education.
As democracy's college, MDC provides high-quality teaching and learning experiences that are accessible and affordable to meet the needs of our diverse students and prepare them to be responsible global citizens and successful lifelong learners. The College embraces its responsibility to serve as an economic, cultural and civic beacon in our community.
The Vision of Miami Dade College is to be a college of excellence, renowned for its Values:


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Terms and Conditions
Program Code: MILITARY. Military ID required to qualify for the offer. At least one guest in a stateroom must be active or retired US or Canadian military personnel to qualify for Military rate. Fare is shown in U.S. Dollars. Fare is cruise only, per person, based on double occupancy. Offer is valid for new individual and new group bookings and cannot be held as group block Qualifying new individual reservations can be moved into existing group. Offer combinable with LATITUDE, LATVIP, LATOBC1. The Haven and Suites are excluded. Guests who cancel and rebook must accept this promotion's Terms and Conditions Government taxes & fees, and onboard service charges are additional IMPORTANT NOTICE: Norwegian Cruise Line reserves the right to charge a fuel supplement without prior notice should the closing price of West Texas Intermediate Fuel increase above $65 per barrel on the NYMEX (New York Mercantile Exchange Index). In the event a fuel supplement is charged, Norwegian Cruise Line will have sole discretion to apply the supplementary charge to both existing and new bookings, regardless of whether such bookings have been paid in full. Such supplementary charges are not included in the cruise fare. The fuel supplement charge will not exceed $10.00 per passenger per day Offer is capacity controlled, subject to availability, subject to change without notice, may be withdrawn at any time, and will be applied to select sailings/select categories. Offer combinability with other promotional offers is subject to change at any time per Norwegian Cruise Line discretion. Other restrictions may apply. Promotion valid in United States &Canada Norwegian Cruise Line is not responsible for typographical errors or omissions. Ships registry: BAHAMAS and UNITED STATES OF AMERICA. ©2011 NCL Corporation Ltd


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Related Links
Recommended Software
Just some of the cool productive and handy tools we use, some of them Freeware, all of them useful.
Search Engines & Directories
Professional Development believe in giving our clients the best possible start in Web Marketing. Submitting your web site in the following directories will assist your web marketing and improve rankings in search engines by utilising one of the most powerful web marketing techniques, reciprocal linking.
Search Engine Optimisation (SEO)
Good SEO can ensure more traffic to your website. Great SEO can generate more qualified traffic. Here are some excellent sites with good tools and information for improving SEO for your website.
Sponsorship or Charitable Trust
Professional Development Ltd are proud to support the following organisations with sponsorship of services so they may continue the good work and spread the word.
ProDev Webmail
Maps Online
If you are looking for an address, the following maps can help you find where or what you are looking for...


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- Musician's Friend Best Selection, Price & Service. Guaranteed.
Call our Gear Heads
at: 800-449-9128
Call our Gear Heads
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Mellow toned, powerful, perfect for semi-acoustic and acoustic jazz guitars.
The G, D, A and low E strings are nickel flatwound for the perfect mellow tone and feel. Custom jazz guitar string set designed by Thomastik-Infeld for George Benson.
Gauges: .012 - .016 - .020(wound) - .028 - .039 - .053.
If you like George's sound, Thomastik-Infeld George Benson Custom Rondwounds will take you a big step in that direction. Order today.
Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


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Buy Velvet Shawls beautiful Evening Velvet Shawl Wraps - Available at up to 70% off and a gift. Buy Velvet Evening Shawls & Wraps in black, red, purple, brown and other colors... look beautiful and fashionable and save big. Buy evening velvet ponchos capes for evening wear for any special occasion or event.
To view our Entire Evening Shawls & Wraps Click Here For Evening Bags Click here.
A Gift with every purchase. Buy your Velvet Shawls & Wraps from us and we will ship them with an extra gift from us too!


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TOPIC: no communications from girls
|Start 21 to 21 of 21
|User Details are only visible to members.
Hey why is it that guys like to get communication from girls but the girls don't communicate back. I, the woman, get texts, calls pics and emails from guys all the times. but my hubby never finds girls who test email or call before or after any playtimes. he craves the attention and enjoys the talking and compliamenting the girls. he just wishes more girls enjoyed the communications like him. he even says how nice playtimes was for us as a couple but usually get no responses. Girls he is a great gentleman who wants to be sweet to the ladies but don't seem to be allowed. Please spread the word...nice guys are out there too.
San Antonio TX
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(7 posts)
|Start 21 to 21 of 21
TOPIC: no communications from girls


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Pitch, Create Animate by Iloura
Pause Fest
Sunday, 11 November 2012 from 12:30 PM to 2:00 PM (AEDT)
Event Details
Iloura's Advertising specialists takes you behind the scenes of one of the most respected animation, vfx and design studios in Melbourne.
Step inside the minds that that make up one of the premiere studios in Australia as they showcase and dissect their recent projects – from pitch to completion.
The panel discussion will be followed by a Q&A session where the Executive Producer, Head of Design and Head of VFX of Iloura Advertising answer all the questions you have ever had about breaking into the industry and executing the big name jobs.
So, if you're a budding animator, producer or designer don't miss out on this opportunity to gain real industry knowledge from the people who do it best!
Executive Producer of Advertising
Head of VFX
Design Director
For this workshop you need experience in animation/motionography/ design or producing at a beginner level.
No equipment needed, just happy faces.
Capacity: 70 People
When & Where
Rancho Notorious
361 Little Lonsdale St / Enter via Heape Crt La
Melbourne VIC 3000
Victoria 3000
Sunday, 11 November 2012 from 12:30 PM to 2:00 PM (AEDT)
Add to my calendar
Pause Fest
Pause Fest is Australia's premier digital event, exploring the intersection of creativity, technology and entrepreneurship.
From humble beginnings in 2011, Pause has rapidly grown to become one of the most anticipated events on the bustling Australian festival calendar, focused on supporting and showcasing the most creative talent on the planet.
Pause Fest attracts a powerful mix of industry professionals, startups and early adopters from a broad range of digital disciplines. The event represents a unique opportunity for locals to connect, collaborate and launch projects alongside global leaders and visionary brands.
Each Pause festival tells a story through a unique theme.
In 2015, the theme is PURE
Please note: We are unable to give refunds if you simply change your mind or make a wrong decision.
For any other ticketing issues feel free to contact us.


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- Audio: Lorant lecture
- Audio: Pompeii introduction
The Annual Eva Lorant Memorial Lecture: Sounding the cornu: music of the Etruscans
Peter Holmes, a trumpet-playing engineer who wrote his PhD thesis on the brass instruments of ancient Europe, examines the trumpets and horns of the Etruscan world.
Peter demonstrates his recreations of Etruscan instruments with fellow members of the Trans-Siberian March Band.
This event took place on 18 January 2013.
Image: Peter Holmes playing his reproduction of an Etruscan cornu. © Placido Scardina
Related playlists
Using this on a mobile device? Tap the image to watch.
On desktop, requires Flash player or click image to download.


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« Laboratory Sabotage? |
| The Supreme Court Slams Big Pharma? Not Exactly. »
Posted by Derek
I wanted to do some follow-up on the Makena story - the longtime progesterone ester drug that has now been newly FDA-approved and newly made two order of magnitude more expensive. (That earlier post has the details, for those who might not have been following).
Steve Usdin at BioCentury has, in the newsletter's March 21st issue, gone into some more detail about the whole process where KV Pharmaceuticals stepped in under the Orphan Drug Act to pick up exclusive marketing rights to the drug. The company, he says, "arguably has played a marginal role" in getting the drug back onto the market.
Here's the timeline, from that article and some digging around of my own: in 1956, Squibb got FDA approval for the exact compound (progesterone caproate) for the exact indication (preventing preterm labor), under the brand name Delalutin. But at that time, the FDA didn't require proof of efficacy, just safety. There were several small, inconclusive academic studies during the 1960s. In 1971, the FDA noted that the drug was effective for abnormal uterine bleeding and other indications, and was "probably effective" for preventing preterm delivery. In 1973, though, based on further data from the company, the agency went back on that statement, and said that there was now evidence of birth defects from the use of Delalutin in pregnant women, and removed any of these as approved uses. In the late 1970s, warning language was further added. In 1989, the agency said that its earlier concerns (heart and limb defects) were unfounded, but warned of others. By 1999, the FDA had concluded that progesterone drugs were too varied in their effects to be covered under a single set of warnings, and took the warning labels off.
In 1998, the National Institute of Child Health and Human Development launched a larger, controlled study, but this was an example of bad coordination all the way. By this time, Bristol-Myers Squibb had requested that Delalutin's NDAs be revoked, saying that they hadn't even sold the compound for several years. This seems to have also been a move, though, in response to FDA complaints about earlier violations of manufacturing guidelines and a request to recall the outstanding stocks of the drug. So the NICHD study was terminated after a year, with no results, and the drug's NDA was revoked as of September, 2000.
The NICHD had started another study by then, however, although I'm not sure how they solved their supply problems. This is the one that reported data in 2003, and showed a real statistical benefit for preterm labor. More physicians began to prescribe the drug, and in 2008, the American College of Obstetricians and Gynecologists recommended its use.
So much for the medical efficacy side of the story. Now we get back to the regulatory and marketing end of things. In March of 2006, a company called CUSTOpharm asked the FDA to determine if the drug had been withdrawn for reasons of safety or efficacy - basically, was it something that could be resubmitted as an ANDA? The agency determined that the compound was so eligible.
Meanwhile, another company called Adeza Biomedical was moving in the same direction (as far as I can tell, they and CUSTOpharm had nothing to do with each other, but I don't have all the details). Adeza submitted an NDA in July 2006, under the FDA's provision for using data that that applicant had not generated - in fact, they used the NICHD study results. They called the compound Gestiva, and asked for accelerated approval, since preterm delivery was accepted as a surrogate for infant mortality. An advisory committee recommended this in August of 2006, by a 12 to 9 vote. (Scroll down to the bottom of this page for the details).
The agency sent Adeza an "approvable" letter in October 2006 which asked for more animal studies. The next year, Adeza was bought by Cytec, who were bought by Hologic, who sold the Gestiva rights to KV Pharmaceuticals in January 2008. So that's how KV enters the story: they bought the drug program from someone who bought it from someone who just used a government agency's clinical data.
The NDA was approved by the FDA in February 2011, along with a name change to Makena. By this time, KV and Hologic had modified their agreement - KV had already paid up nearly $80 million, with another $12.5 million due with the approval, and has further payments to make to Hologic which would take the total purchase price up to nearly $200 million. That's been their main expense for the drug, by far. The FDA has asked them to continue two ongoing studies of Makena - one placebo-controlled trial to look at neonatal mortality and morbidity, and one observational study to see if there are any later developmental effects. Those studies will report in late 2016, and KV has said that their costs will be in the "tens of millions". So they paid more for the rights to Makena than it's costing them to get it studied in the clinic.
That only makes sense if they can charge a lot more than the generic price for the drug had been, of course, and that's what takes us up to today, with the uproar over the company's proposed price tag of $1500 per treatment. But the St. Louis Post-Dispatch (thanks to FiercePharma for the link) says that the company has now filed its latest 10-Q with the SEC, and is notifying investors that its pricing plans are in doubt:
The success of the Company's commercialization of Makena™ is dependent upon a number of factors, including: (i) the Company's ability to maintain certain net pricing levels for Makena™; (ii) successfully obtaining agreements for coverage and reimbursement rates on behalf of patients and medical practitioners prescribing Makena™ with third-party payors, including government authorities, private health insurers and other organizations, such as HMOs, insurance companies, and Medicaid programs and administrators, and (iii) the extent to which pharmaceutical compounders continue to produce non-FDA approved purported substitute product. The Company has been criticized regarding the list pricing of Makena™ in a number of news articles and internet postings. In addition, the Company has received, and expects to continue to receive, letters criticizing the Company's list pricing of Makena™ from several medical practitioners and several advocacy groups, including the March of Dimes, American College of Obstetricians and Gynecologists, American Academy of Pediatrics and the Society for Maternal Fetal Medicine. Further, the Company has received one letter from a United States Senator and expect to receive another letter from a number of members of the United States Congress asking the Company to reduce its indicated pricing of Makena™, and the same Senator, together with a second Senator, has sent a letter to the Federal Trade Commission asking the agency to initiate an investigation of our pricing of Makena™.
The Company is responding to these criticisms and events in a number of respects. . .The success of the Company is largely dependent upon these efforts and appropriately responding to both the media and governmental concerns regarding the pricing of Makena™.
Personally, I'm torn a bit by the whole situation. I think that people and companies have the right to charge what the market will bear for their goods and services. But at the same time, I find myself also very irritated by KV in this case, because I truly think that they are taking advantage of the regulatory framework. As I said in the last post, it's not like they took on much risk here - they didn't discover this drug, didn't do the key clinical work on it, and don't even manufacture it themselves. Their business plan involves sitting back and collecting the rent, but that's what the law allows them to do.
In the end, if political pressure forces them to back down on their pricing, this will come down to a poor business decision. Companies should, in fact, charge what the market will bear - but KV may have neglected some other factors when they calculated what that price should be. Before setting a price, you should ask "Will the insurance companies pay?" and "Will Medicare pay?" and "Will people pay out of their own pocket?", but you should also ask "Will this price bring down so much controversy that we won't be able to make it stick?"
Comments (17)
+ TrackBacks (0) | Category: Clinical Trials | Drug Development | Drug Prices | Regulatory Affairs | Why Everyone Loves Us
1. NoDrugsNoJobs on March 24, 2011 9:30 AM writes...
I think the lawsuit liability for this drug will be huge. Most if not all major pharma walked away from programs related to treating pregnant women because any issues with the baby can result in huge liability to the manufacturer. Birth defects and child disability is common enough but within a population of women with problems related to carrying a baby to term and the rates probably go up even more. A single successful lawsuit can result in a judgment of many millions of dollars. If the drug is used by a lot of women you can be sure that there will be lots of lawsuits. One of the first mass torts was for a pregnancy related synthetic estrogen called diethylstilbestrol ("DES").
2. Rick on March 24, 2011 9:36 AM writes...
Setting aside the philosophical issues of pricing and free market capitalism, the birth defect issue is deeply troubling. From your description and the BioCentury piece, it seems that there are a lot of "cracks" through which unfavorable observations can fall. How solid are the birth defect data?
It also seems like the number of times this drug has been handed off will inevitably create a terrible legal morass if, God forbid, any birth defect litigation does arise. KV will just point the finger at Hologic, who will point the finger at Cytec, who will point the finger at Adeza, will blame NICHD, who will stare back in blank silence. The net result would be that KV's, Hologic's, etc. laywers will make a lot of money, but damages will never be assesed before KV gets a chance to sell Makena to someone else (at a profit that will more than adequately cover their expenses, plus a nice multi-hundred million dollar premium). It could make sifting through the whole BP/Halliburton/Transocean finger-pointing fiasco look like an open-and-shut case.
3. RM on March 24, 2011 10:49 AM writes...
Derek, implicit in the "companies should charge what the market will bear" concept is the understanding that if one company is charging an excessive amount, another company can come in, charge less, and hand the unreasonable company their hat. That sort of falls apart when you have the government blocking other companies from stepping in.
In drug approval (or other patent-related) case, we usually allow it, though, to curtail a possible drawbacks of the completely-free market ... the major one of which usually goes something like "a hard working person puts in a lot of time and effort to research and develop a product, but before they can even recoup the costs of that development, a big corporation sweeps in, takes advantage of all their work (without payting them) and undercuts them on price (because they don't have to pay for any of the R&D)" -- If KV looks like one of the players in that scenario, it's not the one exclusivity was intended to protect.
4. Ceee on March 24, 2011 11:12 AM writes...
Derek - KV mgmt demonstared what goes on in many companies. Mgmt does not believe in market research or in soliciting customer insights and feedback. Had they done that, they would have have known that the many stakeholders would not respond well to a $1500 price tag.
The result is usually commercial failure of a brand/drug that has so much promise.
5. johnnyboy on March 24, 2011 11:24 AM writes...
Wow, what an amazingly convoluted story for that drug. Thanks for that, Derek.
6. Ash on March 24, 2011 11:40 AM writes...
Is this an "orphan Drug" Does anyone have information on how many women require such a treatment. They would need 150k to 175k patient treatments jsut to break even with the 1,500 per treatmetn price tag.
I also have to agree with the liability argument. Possible litigation arising frmo birth defects could be very expensive.
7. fyi on March 24, 2011 12:32 PM writes...
Rates for preterm labor from Wikipedia........
"In Europe and many developed countries the preterm birth rate is generally 5–9%, and in the USA it has even risen to 12–13% in the last decades."
8. Mr. Happy on March 24, 2011 1:09 PM writes...
"...what the market will bear"
Thats why all those lobbyists exist in Washington...and too big to fail financial institutions...nah the predators at JP Morgan and Goldman Sachs have nothing on Kevin Trudeau when it comes to fraud.
9. partial agonist on March 24, 2011 2:35 PM writes...
agree with #1 on the huge liability risk.
In the 60's the H1 antagonist drug Bendectin was used in the USA for morning sickness. The pharma company (Merell Dow) was sued again and again for alleged birth defects, won every single case, the FDA supported them on the lack of evidence for teratogenicity, yet finally they got tired of bad press and expensive lawyers and pulled it from the market. 28 years later it is still sold in Europe and Canada. Moral- don't try to sell anything for pregnant women.
Years later they came out with nicotine gum and patches and wanted to have them labeled to be NOT used by pregnant women, since nicotine toxicity is known. The FDA refused, saying they don't want preganant women smoking, and that trumps the gum or patch risk, and the company would just have to deal with any legal liability.
10. Jill on March 24, 2011 4:00 PM writes...
Ash, the $1,500 "per treatment" really is per DOSE. The average pregnant woman is given a 20 week course of this drug for a total cost of $30,000 per pregnancy. It is the $30,000 price tag for preventing prematurity that has women up in arms.
I was on a non FDA approved version of 17OHP during my recent pregnancy (my son was born 11/10). My daughter, born in 2009, was premature and my doctor felt this drug was a highly effective, low risk option. My son was thankfully born full term and healthy. I believe I have 17OHP to thank.
It is sad to me that some women will be forced to make an impossible decision between high risk for prematurity and finding $30,000 to pay for a drug that was $10/dose ($200 for an entire pregnancy) less than a year ago.
11. BE on March 25, 2011 8:05 AM writes...
The woman that cuts my hair had a baby 4 months early - the baby was lucky and survived. It took 3 months of the baby being in intensive care at a cost of $600,000.00 and all the bills have not been counted. That equates to around $6,500.00 a day ($1,500.00 a day just for the bed). I understand that KV is setting up a program for women who might need assistance. The FDA approval status will allow more doctors to prescribe Makena to high risk patience - potentially saving millions and millions in insurance claims. What about the cost of a couple of Tylenol when you receive them in a hospital. The astronomical pricing can be traced to the need for tort reform in this country - unnecessary and frivolous law suits and malpractice insurance not to mention the quagmire of administrative costs that exist in this country that account for 2/3rds of medical costs in this country. In my opinion, this is a fantastic drug and needs to be brought to market with the FDA stamp of approval. People need to get off KV's back and let the process work it out. When was the last time someone was turned away for treatment after they had a serious accident – almost never! Now the system has a chance to be PROACTIVE – every week that a baby stays in the womb dramatically increases the baby's chance for survival. Makena needs to be accessible – FDA approval will allow doctors to prescribe the treatment and minimize their risk of being sued. Doctors will also be involved in prescribing correct dosages, etc… In addition, has anyone thought about the need for profit's in this country – maybe KV's profits will allow the funding for new kinds of drugs that may one day cure Cancer, etc… The cost of developing new drugs is astronomical not to mention time consuming – it can take years if not decades to approve some of these drugs! Get off KV's back and be thankful this drug is on the market and accessible with the all important FDA certification!
12. Derek Lowe on March 25, 2011 10:18 AM writes...
BE, you really should read some more posts around here. No one's disputing that preventing preterm delivery is a desirable outcome. But a large number of doctors were already prescribing progesterone caproate before - a survey showed about 65% of the respondents in Ob/Gyn practices had done so during the previous year. And no one, to the best of my knowledge, was getting sued.
FDA certification is indeed worth something - but in this case, is it worth as much as KV is charging for it? That's the question. I say "no", for a long-used and well-studied drug like this one, but you can certainly disagree. To me, this looks like rent-seeking, pure and simple.
Finally, you don't have to tell anyone around here about the cost of developing new drugs and the need for profits in the drug industry. That's where a lot of us (including me) work. The problem here is that companies like KV do not discover new drugs. They manufacture things that other people have spent the money to discover. And in KV's case, they're not even manufacturing anything, having been barred by the FDA from that activity.
13. Kieth on March 27, 2011 2:42 PM writes...
Thanks Derek, you made a long story very interesting. None of the comments claim that KV just paid too much for the rights in the first place which, to me anyway, seems likely. Shouldn't FDA approval protect KV from suits?
apparently no one here thinks so and that is puzzling to this civilian.
14. Jim on March 28, 2011 5:13 PM writes...
The New England Journal of Medicine has a great article on the topic from the March 18,2011 edition entitled, "Unintended consequences--the cost of preventing preterm births after FDA approval of a branded version of 17OHP" by Joanne Armstrong MD, MPH.
It will provide clearity to most of the questions on this blog.
15. Jim on March 28, 2011 5:14 PM writes...
The New England Journal of Medicine has a great article on the topic from the March 18,2011 edition entitled, "Unintended consequences--the cost of preventing preterm births after FDA approval of a branded version of 17OHP" by Joanne Armstrong MD, MPH.
It will provide clarity to most of the questions on this blog.
16. Jennie on March 29, 2011 4:38 AM writes...
The outrage is more than justified. Premature birth affects very poor women most, meaning much of the $30,000 per pregnancy cost would have to be picked up by Medicaid. This amounts to a huge transfer -- billions of dollars a year -- from taxpayers to the private sector, all for a product whose efficacy was established by taxpayer-funded research and which normally costs something like $10 a dose to compound. Only in America. It was a very cynical move by an extremely shady company. KV barely survived a fraud investigation over mislabeled morphine (its pills contained twice the labeled amount) and its former CEO was just sentenced in connection with this.
17. petros on March 30, 2011 11:27 AM writes...
And now the FDA has thrown a large spanner into KV's pricing strategy
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Audit: Md. Backlogged In Payments To Crime Victims
February 19, 2012 7:28 PM
WASHINGTON (AP) — A new state audit says Maryland lacks the money needed to make payments owed to victims of crime in the state.
The Washington Examiner reports that the state audit shows a $2.6 million backlog in payments as of June
2011. The audit also found problems with the distribution of payments including required but missing documentation.
In a written response to the report's findings, an official with the Maryland Department of Public Safety & Correctional Services said the department has made or will be making changes to address the problems.
In 2011 about 1,000 claims were approved, totaling $5.2 million.
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Arlington, VA (May 14, 2013) – Virginia Hospital Center today announced that it is the first hospital in the Washington metropolitan area to offer the MarginProbe System, a revolutionary device which delivers real-time breast cancer margin assessment during surgery. This device helps surgeons make sure that all cancerous tissue is removed around a breast cancer site by assessing the electromagnetic response of healthy vs. cancerous tissue, allowing for an easy and instant assessment of cancer on the margin of excised tissue. This has been shown to reduce the likelihood of a second surgery by delivering clarity in the operating room. Virginia Hospital Center is among the first group of five hospitals in the country to get this technology.
"We are proud that Virginia Hospital Center is first in the region to offer this ground-breaking technology to our breast cancer patients undergoing breast conservation surgery," said Dr. Stephanie Akbari, Medical Director of the Reinsch Pierce Family Center for Breast Health at Virginia Hospital Center and a breast surgery expert. "This unique device allows surgeons to detect cancer cells on the edge of the removed tissue while performing a lumpectomy, making it easier to excise additional tissue if necessary in the same procedure. We are utilizing the most accurate, effective cancer detection tools available."
MarginProbe characterizes cancer cells by assessing the electromagnetic response of tissue. This allows the surgeon to capture the minute differences between healthy tissue and cancerous tissue at the time of surgery. If cancerous cells are found at the margins, the surgeon can excise the additional tissue during the initial surgery. In a 664-patient prospective, multi-center, randomized, double arm study, this device was shown to reduce the re-excision rate by 56%. Historically, between 30%-60% of women who undergo breast conservation surgery have to undergo additional surgeries because of an inability to achieve negative margins during the first surgery. This pivotal trial data showed that by using the MarginProbe System during the first operation, in conjunction with standard methods, surgeons have the ability to significantly reduce the rate of positive margins following the initial surgery. This will represent a potentially significant emotional, physical, and financial cost savings for every breast cancer patient undergoing breast conservation surgery.
For over 65 years, Virginia Hospital Center has provided exceptional medical services to the Washington metropolitan area. Virginia Hospital Center is a 342-bed, state-of-the-art facility offering comprehensive healthcare and multiple Centers of Excellence including Cardiology and Cardiovascular Surgery, the Reinsch Pierce Family Center for Breast Health, Neuroscience, Oncology, Total Joint Replacement (hip and knee), Women and Infant Health, Bariatric Surgery and Urology. One of America's 100 Top Hospitals®, Virginia Hospital Center is a teaching hospital, long-associated with Georgetown University's School of Medicine, and accredited by The Joint Commission and Licensed by the Commonwealth of Virginia Department of Health. For additional information, please visit www.virginiahospitalcenter.com.
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First off, direct-to-DVD movies are limited to c. 70 minutes for budgetary reasons -- given the projected DVD sales and rental income, a longer movie would cost too much to be profitable. So that would have no bearing on the potential length of an animated theatrical feature.
However, plenty of animated feature films are, in fact, between 70 and 90 minutes. To pick some Disney films, Alice in Wonderland was 75 minutes, Snow White was 84 minutes, Pocahontas was 81 minutes, Aladdin was 90 minutes, and Dumbo was only 63 minutes. The three Toy Story films were 81, 92, and 103 minutes (each exactly 11 minutes longer than the last!). The two Kung Fu Panda films were 88 and 90 minutes. The Incredibles was actually fairly long at 115 minutes, but Megamind is 96.
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Summer Slaughter 2011
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I know this is my first post here and some may question the credibility of it, but if you head over to the show-setlists forum on AbsolutePunk you will see I announce tours weeks and months before they are announced a pretty consistent basis.
With doing this, I have a "respect" thing i go by. If the band isn't currently out on a tour or has one coming up before that tour, I will spill the beans (see: Bayside/Silverstein co-headlining tour this spring, Current Parkway Drive tour, Between The Buried And Me/Job For A Cowboy)
I can say the two bands co-headlining this year's summer slaughter HAVE been mentioned in this thread already. Some could argue it is a co-co headliner with the third band that is confirmed to be playing. They are a pretty well respected band, but it is being billed as a co-headliner from my understanding.
Hopefully I can post more about this soon! Don't mean to tease you guys. You might be able to figure it out. Both co-headlining bands are good friends.
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Father and son's trail in honour of FA Cup
Posted: May 19, 2014|
A father and son watched the FA Cup final at Wembley – after travelling more than 5,000 miles in nine months to watch every round of the competition.
Mike and Paul Vallis, aged 16, went to games in Plymouth, Northampton, Derbyshire, Essex and Hull in their bid to watch the winning team from each round progress.
They spent £1,300 along the way and completed their FA Cup trail when they headed to Wembley Stadium to watch Hull City lose to Arsenal on Saturday. Mike, of Plymouth, Devon, said: "I'm that age that when I was a kid, the FA Cup final day was more important than Christmas day. The FA cup has still got that magical appeal."
They started their own FA Cup run way back in August when they watched Plymouth Parkway take on Saltash United, beating them 2-0 in front of a crowd of 178 people.
Following the winner of each round has seen them travel as far as 672 miles in a round-trip for a game, when they went to see Hull City against Sunderland in the quarter final.
"Some games were forgettable but others were true cup ties," Mr Vallis said.
"The 4-3 replay between Clevedon Town and Hartley Wintney had everything and was a classic.
"There were a couple of penalties, plenty of goals and the winner was scored in the 96th minute from a controversial penalty.
"I enjoyed watching the grassroots football almost as much as watching the full-time professionals.
"With clubs like Clevedon, they got really small crowds and we do wonder how they keep going. Paul quite liked following them. As the games got bigger, the atmosphere got more and more exciting.
"Particularly the semi-final when it was 5-3 against Sheffield United."
The Babcock manager and Plymouth College pupil started pursuing Hull City's fortunes after they beat Southend United 2-0 away in the fourth round, giving the cup run added meaning.
"When I was a young lad, my parents moved to Hull and I went to college there," explained the father-of-two.
"We went to the quarter-final against Sunderland and it was the first time I had been back in a while but it was a good visit.
"The truth is, we have both become Hull fans.
"It was when we watched Hull versus Brighton and stood in the away end, we felt that sense of camaraderie with the fans.
To secure tickets to some of the contests, Mike even booked the day off work to make sure he could get them.


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> Regent Seven Seas Cruises' Mariner: Panama Canal
Regent Seven Seas Cruises' Mariner: Panama Canal
Day 1: Ft. Lauderdale
Day 2: At Sea
Day 3: Grand Cayman
Day 4: San Andres Island/At Sea
Day 5: Panama Canal/Gatun Yacht Club
Day 6: Puntarenas
Day 7: Huatulco
Day 8: Cabo San Lucas
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Day 10: Back on Terra Firma
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Day 4: Friday, San Andres Island/At Sea
En route to San Andres Island and a two-hour port call solely for the purpose of filing paperwork to comply with a bit of convoluted maritime law, we had reached that stage of a cruise where impressions begin to solidify and areas of strength and weakness start sorting themselves out.
At this point in the cruise, our favorite element of the ship and voyage is the food. It has been consistently interesting, beautifully presented, tastily prepared and promptly brought to the table piping hot.
Our biggest disappointment is the Internet cafe. In filing stories electronically from ships for seven years or more, I have sat down at the keyboards of Internet cafes of every stripe on a wide variety of ships and lines, all the way from Windows 95 laptops connected to cell phones (on a Yangtze River cruise in China) to broadband/satellite hookups (in Digital Seas installations) that are every bit as fast as my home-based DSL connection. Mariner's connection is not the slowest I've encountered, but darn close to it, and, at $0.75 per minute, at the upper extreme of price. Fortunately, those rates are based on minutes spent actually uploading or downloading data, not time you spend watching the little hourglass spin end over end. Nonetheless, waiting for five minutes minimum from the time you click on the button to time your mailbox actually appears on the screen gets old fast.
The best surprise: the quality of the production entertainment.
The pet peeve we weren't expecting: the paucity of hanging art, save for samples of pieces from Park West's auction inventory.
Our favorite little detail: the ship's library area. Not only are the shelves unlocked (for books, video or games) 24 hours a day, but in the hallway alongside the library are a pair of jigsaw puzzles. At embarkation they are nothing but a pile of disconnected pieces, but as people walk by they put in a piece or two, and, as a community effort in the course of three or four days, the puzzles get completed.
The detail we missed the most: there is no "pool band" on the ship. Though the itinerary is not, strictly speaking, purely a Caribbean jaunt, and therefore a Soca or Reggae band would only be on-target for the first half of the trip, there should be some combo with both a Latin and island flavor for sailaways and poolside music. Mariner uses their five-piece show band from the Constellation Theater -- when they have any poolside music at all -- and it just doesn't quite fit.
As with most sea days, today featured two enrichment lectures in the Constellation Theater. The one we attended was on coral reefs conducted by Estelle Davies, a naturalist with Jean-Michel Cousteau's Oceans Futures Society, which has partnered in projects with Regent Seven Seas Cruises. Estelle's lecture likened coral reefs to ecologically enlightened cities, powered by solar energy, with creatures who take on all the roles of city maintenance, from dealing with refuse to harvesting food to providing healing. Her presentation was not without a few commercial plugs for Cousteau's upcoming PBS television series, but it was still very well received.
After the lecture we decided to try lunch in the Compass Rose. The menu for the open seating restaurant included many of the items available at La Veranda Buffet upstairs, but there were a number of other offerings as well, including sandwiches, salads, seafood and pasta selections, all served to order. My wife and I both ordered a lentil soup with sausage, which she followed with a Cajun chicken breast sandwich with some of the best crispy little French fries I can recall. I went for a mixed seafood salad on sliced avocados and mixed greens. Both meals were excellent.
After lunch we visited Mariner's small casino, where we played for a while at one of the room's three black jack tables. The room is much less glitzy than the typical cruise ship casino, which seemed to promote a quieter, more civilized ambience. Dealers were friendly, but the cards weren't, so we packed it in until afternoon when we watched the low-slung San Andres Island loom over the horizon, looking very much like one of the smaller Bahamas -- low elevation, lots of palm trees, and beautiful turquoise-hued shallow water surrounding sandy beaches backed by thickets. We heard the anchor descending and the engines shut down, but by the time we had showered for dinner we were already on our way again, bound for the Panama Canal.
After another dinner in Compass Rose we went to check out Chris Pendleton, the comedienne who had already performed the first night. We listened to about 20 minutes of her act, but when the jokes reverted to the typical fodder for cruise ships -- toilets, overeating at buffets, etc. -- we decided to hit the hay, planning on an early start to catch the first moments of our entry in to the Canal's Gatun locks.
Day 3: Grand Cayman
Day 5: Panama Canal/Gatun Yacht Club
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