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GRAND RAPIDS (WZZM) - LaughFest is bringing a Clean Comedy Showcase to Grand Rapids.
Ten comedians have been pre-selected for their unique ability to bring laughs without vulgarity. These are some of the most requested comedians by companies across the country! Five comedians will be featured in Showcase I (on Friday and Saturday) and five different comedians will be featured in Showcase II (on Friday and Saturday). See all ten by going to both Showcases.
And, here's where you can get involved. The community will determine the winner of "You Made Us Laugh The Most" Award in this Showcase through voting held at each individual showcase. *Please note, while you can expect clean comedy at these shows, they are geared towards adults so leave the kids at home.
Clean Comedy Showcase I takes place on the following dates at times: Friday, March 11 at 6:00pm (with Dinner** 3rd Floor of THE BOB), Friday, March 11 at 9:30pm (at Dr. Grins at THE BOB), Saturday, March 12 at 7:00pm (at Dr. Grins at THE BOB), Saturday, March 12 at 9:30pm (3rd Floor of THE BOB) .
Watch Tara Kuhnlein's interview with some of the comedians in the video above.


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Professor Oswald said: "Status seems to work a kind of health-giving magic. Once we do the statistical corrections, walking across that platform in Stockholm apparently adds about 2 years to a scientist's life-span. How status does this, we just don't know."
The researchers also looked at the Nobel Prize fund - the real value of which has changed over time. By comparing the possible effects of that variation, they found that the amount of actual prize money won by Nobel prize winners had no effect on their longevity - suggesting that it is the sheer status boost of the award that is important in extending lifespan.
The researchers also looked to see if the number of nominations for a Nobel Prize had any effect as a number of the scientists in the survey had been nominated for the award several times. They found that the number had no effect- actually winning the Nobel Prize was what counted.
Source:University of Warwick

subset: commoncrawl


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One of the many things that makes the Zita West Assisted Fertility Programme different from traditional approaches to assisted conception is our simple, step by step approach to helping you to get pregnant. We won't recommend that you opt for IVF if there's a reasonable chance that either nature or more low level assisted fertility approaches might be worth a try first. Which is why, if you are experiencing ovulation problems, or if your partner is sometimes impotent or suffers from premature ejaculation, we may recommend trying Intra Uterine Insemination - IUI - as a first step, before considering IVF.
Success rates for IUIs are lower that with IVF or ICSI (the clinical pregnancy rate of women aged 36 or less is between 15-20%) but the procedure is much quicker and less expensive and, depending on your individual circumstances, can sometimes be done without fertility drugs to boost egg production though, as you would expect, this reduces the likely success rate further.
For some couples this will be the most sensible first step.
For details of fees CLICK HERE


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To learn more about this training CD-Rom and how to order it, please see our order page.
Useful Water Security Web Links
|Federal Links
|Environmental Protection Agency - Water Security Division
National Response Plan
EPA Lab Compendium (searchable database of labs and their capabilities, requires registration)
EPA LEPC Database (Find Your Local Emergency Planning Committee)
CDC Emergency Preparedness & Response
CDC, "Bioterrorism Alleging Use of Anthrax and Interim Guidelines for Management - United States, 1998"
Chemical and Biological Defense Information Analysis Center
Department of Homeland Security
Department of Homeland Security - Critical Infrastructure
Federal Bureau of Investigation (FBI)
National Cyber Security Division, the United States Computer Emergency Readiness Team (US-CERT)
Federal Emergency Management Agency (FEMA)
National Disaster Medical System
EPA National Homeland Security Research Center (EPA ORD)
National Response Center
Terrorism Research Center
|Water Sector Links
|American Water Works Association
The America Works Association (AWWA) aims to advance public health, safety and welfare by uniting the efforts of the entire water community. The link to the homepage is most appropriate because the entire AWWA provides links to water security conferences, education and training, science and technology, and a Water Infrastructure Security Enhancement webpage that provides utilities with links to water security guidance documents, training and resources.
National Association of Clean Water Agencies
Formerly the Association of Metropolitan Sewerage Agencies, now called the National Association of Clean Water Agencies (NACWA), represents the interests of the nation's wastewater treatment agencies and environmental practitioners that serve the majority of the sewered population. The homepage provides links to water security conferences, education and training, science and technology, etc. Additionally, the NACWA web site offers a Clean Water Advocacy Security webpage that provides wastewater utilities with links to reports regarding improving security at wastewater plants and protection of wastewater infrastructure.
Association of Metropolitan Water Agencies
The Association of Metropolitan Water Agencies (AMWA) is an organization of the largest publicly owned drinking water systems in the United States. Since there is no dedicated water security page on this site, the links a user of the CD would want to access can be found on the home page.
Association of State Drinking Water Administrators
The Association of State Drinking Water Administrators (ASDWA) is a non-profit organization designed to assist state drinking water representatives with regulating drinking water and assisting water utilities with all aspects of providing clean water. The ASDWA website includes links to water security related resources, events, and publications.
AWWA Research Foundation
The America American Water Works Association Research Foundation (AwwaRF) is a member-supported, international, nonprofit organization that sponsors research to enable water utilities, public health agencies, and other professionals to provide safe and affordable drinking water to consumers. The AwwaRF website provides browsers with Foundation project descriptions, contract forms for research agreements, request for proposals, conferences, and publications. In addition, the Research Center webpage provides a portal to all Foundation research content.
National Association of Water Companies
The National Association of Water Companies (NAWC) represents all aspects of the private water service industry. The website provides links to their water security programs. NAWC membership appears to be free and available to individuals and companies interested in private drinking water issues.
WaterISAC Information Sharing and Analysis Center
WaterISAC is an organization governed by a Board of Managers, comprised of water utility managers that are appointed by the national drinking water and wastewater organizations. The WaterISAC website offers a secure database, expert analysis, information gathering, and the rapid distribution of reports and government alerts about threats to America's drinking water and wastewater utilities. It is the only centralized, up-to-the-minute resource of its kind serving the water sector.
National Rural Water Association
The mission of the National Rural Water Association (NRWA) is a non-profit federation of State Rural Water Associations. NRWA's mission is to provide support services to State Associations who have more than 24,550 water and wastewater systems as members. Member state associations often with their own websites, offer a variety of state specific programs, services, and member benefits such as training programs and on-site assistance in areas of operation, maintenance, finance, and governance. The NRWA website provides browsers with information regarding conferences, meetings and events.
Water Environment Federation
The Water Environment Federation is a not-for-profit technical and educational organization with members from varied disciplines. WEF's vision to "preserve and enhance the global water environment" is the basis for all WEF programs and activities. The WEF website provides published research documents on water security; announces training opportunities; posts conferences and other special events.
Water Environment Research Foundation
The Water Environment Research Foundation (WERF) is a nonprofit organization that helps utilities and corporations preserve the water environment and protect human health by providing science and technology research to enhance management of water resources. The WERF website provides access to published research articles, WERF news articles, and highlighted publications.
Presidential Decision Directive 63: Critical Infrastructure Protection
Executive Order 13231: Critical Infrastructure Protection
Homeland Security Presidential Directive/HSPD-7
|Contaminant Resources
|Centers for Disease Control Chemical Agents
Centers for Disease Control Biological Agents
Physician Preparedness for Acts of Water Terrorism
This website provides important information to physicians regarding the recognition, diagnosis and treatment of waterborne disease, and the health effects of acute and chronic exposure to water pollution. The introductory information on this website discusses the clinical constraints and time restrictions of practicing clinicians, new diagnostic challenges and the consequences of misdiagnosis. The website offers free access to a Physician On-line Reference Guide, a Continuing Medical Education (CME) module of this Physician On-Line Reference Guide, and other webpages, such as The Basics of Water Safety and Disease Trends, Evaluation and Management of Water-Bourne Disease, Health Risk Communication, and the Clinician Internet Resource Search Engine.
Health Protection Agency (UK) Chemical Agents
The Health Protection Agency is an independent body dedicated to protecting the health and well-being of the population in the UK, in particular from infectious diseases and potential hazards involving chemicals, poisons, or radiation. The link to the website is appropriate because it provides a variety of information on infectious diseases, chemicals, poisons and radiation. In addition, the website contains a section on the UK Centre for Emergency Preparedness and Response (CEPR), accessible from the home-page. The CEPR is dedicated to preparing for and coordinating responses to potential healthcare emergencies (e.g., virulent new strain of disease), including possible acts of deliberate release, such as a bio-terrorist attack.
Water Contaminant Information Tool
|Training Links
|National Incident Management System (NIMS) Training
National Response Plan (NRP) Training
Exercise Design Training
International Association of Emergency Managers (IAEM)
The International Association of Emergency Managers (IAEM)is a non-profit educational organization for the emergency management community. Their website provides information on emergency management, networking and professional opportunities in the field, access to field-related publications and news, as well as a section describing how to become a Certified Emergency Manager.
National Emergency Management Association (NEMA)
The National Emergency Management Association (NEMA) is a non-partisan, non-profit association dedicated to enhancing public safety by improving preparedness for, response to, and recovery from all emergencies, disasters, and threats to national security. Their website provides information on upcoming emergency management conferences, state Hazard Mitigation Officer training course material, as well as the names of state emergency management contacts, and links to other relevant emergency management websites, such as EMAC, the emergency management assistance compact. State directors of emergency management are the core membership of NEMA, other members include homeland security advisors, federal agencies, private sector companies and concerned individuals, but most of the website is accessible to non-members.
National Volunteer Organizations Active in Disasters (NVOAD)
The National Voluntary Organizations Active in Disaster (NVOAD) coordinates planning efforts and communication by many voluntary organizations responding to a disaster. Their website provides a guide to managing spontaneous volunteers, a manual for effective long-term recovery from a disaster, contact information for individual members of NVOAD, listed by state, and encourages volunteers to train, prepare, and become acquainted with each other prior to any disaster response.
Emergency.com: Crisis, Conflict, and Emergency Service News, Analysis, and Reference Information
The Emergency Response and Research Institute website or Emergency.com, is composed of links to relevant emergency response manuals (e.g., NIMS) and articles related to emergency operations and terrorism. It provides the user with an understanding of how certain agencies, such as police, fire, or EMS respond to emergency events.
National Memorial Institute for the Prevention of Terrorism (MIPT)
Memorial Institute for the Prevention of Terrorism (MIPT) is a non-profit institution expanding and sharing knowledge through research, analysis, and training to help prevent terrorism and lessen its effects. The website provides access to a terrorism knowledge base, offering information on terrorist incidents, groups, and trials; terrorism-related resources, such as articles, e-books, etc; a responder knowledge base for emergency responders, including information on standards, training, and grants; lessons-learned reports; and a donation section to support MIPT.
EPA Security Product Guide


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Heading west from Montana or east from Washington atop Interstate 90, we always build in time to stop in the historic silver mining town of Wallace. Sometimes we stop for a pint at the brewpub, other times a shot of espresso and a pastry. Now we'll stop for the cannolis.
A few weeks ago, heading east toward Seattle, we made our usual exit 62 stop. We walked by the quirky bordello museum, the stone chateau of the former Burlington Northern depot and our usual stops, then went into a different place. There on Cedar Street, behind the counter of the D & G Bakery, we met Anne Alexander.
I wanted caffeine and something sweet. "I'm known for my little cheesecakes," Anne said, her Italian New Yorker accent coming out double-shot strong with each syllable. Two bites into a delicious mini huckleberry cheesecake, my fiancee, Jolica, said to Anne: "That was awesome. Any chance you make cannolis?"
Cannoli was my Italian grandma's specialty dessert, and I'll admit to being a cannoli snob. They're hard to find because making them is labor intensive and they demand precise timing not always in synch with customer needs. Anne said, "I make the best, but I need at least a day's notice."
No worries, I said, giving her 18 days notice before our next trip across the top of Idaho.
Grandma used to say the perfect cannoli starts with a shell made from wheat, eggs, sugar and other "secret ingredients." She would lightly fry the shell, then add a filling of cream, ricotta, chocolate chips and more "secret ingredients." The keys were the texture and the timing.
Seventeen days later, we gave Anne the reminder call she requested, but she didn't need it. The shells were done, and ready to be filled when we arrived. She noted, "we will have them like the Sicilian's do: with a shot of espresso, a slight twist of lemon, and a few drips of Sambuca included."
The bakery was actually closed that day, so we knew we were in for a special treat. Anne's husband John joined us to clank glasses and savor an absolutely wonderful dessert. Then another. And one more for good measure.
We like traveling without reservations, but will now make an exception to that rule and call Anne to reserve cannolis whenever we're 24 hours from Wallace. And although we won't expect the off-day family treatment, we'll bank on a welcoming smile and some fantastic Italian treats.
Cheers, John
Written by Guest Blogger John Deleva


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Crowdsourcing, citizen sensing and sensor web technologies for public and environmental health surveillance and crisis management: trends, OGC standards and application examples
1 Faculty of Health, University of Plymouth, Drake Circus, Plymouth, Devon PL4 8AA, UK
2 International Society for Photogrammetry and Remote Sensing, Commission IV - Geodatabases and Digital Mapping, WG IV/4 - Virtual Globes and Context-Aware Visualisation/Analysis, ISPRS Headquarters (2008-2012), National Geomatics Centre of China, Beijing 100048, PR China
3 SENSEable City Lab, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA
4 Institute for Geoinformatics and Remote Sensing, University of Osnabrueck, 49076 Osnabrueck, Germany
5 School of Engineering and Informatics, National University of Ireland Galway, Ireland
6 Digital Enterprise Research Institute (DERI), National University of Ireland Galway, Ireland
7 Department of Earth and Space Science and Engineering, York University, Toronto, ON M3J 1P3, Canada
8 International Society for Photogrammetry and Remote Sensing, Commission III - Photogrammetric Computer Vision and Image Analysis, WG III/4 - Complex scene analysis and 3D reconstruction, ISPRS Headquarters (2008-2012), National Geomatics Centre of China, Beijing 100048, PR China
9 Pacific Northwest National Laboratory, Richland, WA 99352, USA
10 InSTEDD (Innovative Support to Emergencies, Diseases and Disasters), Palo Alto, CA 94306, USA
11 ITRI (Industrial Technology Research Institute), Hsinchu County 310, Taiwan
International Journal of Health Geographics 2011, 10:67 doi:10.1186/1476-072X-10-67Published: 21 December 2011
'Wikification of GIS by the masses' is a phrase-term first coined by Kamel Boulos in 2005, two years earlier than Goodchild's term 'Volunteered Geographic Information'. Six years later (2005-2011), OpenStreetMap and Google Earth (GE) are now full-fledged, crowdsourced 'Wikipedias of the Earth' par excellence, with millions of users contributing their own layers to GE, attaching photos, videos, notes and even 3-D (three dimensional) models to locations in GE. From using Twitter in participatory sensing and bicycle-mounted sensors in pervasive environmental sensing, to creating a 100,000-sensor geo-mashup using Semantic Web technology, to the 3-D visualisation of indoor and outdoor surveillance data in real-time and the development of next-generation, collaborative natural user interfaces that will power the spatially-enabled public health and emergency situation rooms of the future, where sensor data and citizen reports can be triaged and acted upon in real-time by distributed teams of professionals, this paper offers a comprehensive state-of-the-art review of the overlapping domains of the Sensor Web, citizen sensing and 'human-in-the-loop sensing' in the era of the Mobile and Social Web, and the roles these domains can play in environmental and public health surveillance and crisis/disaster informatics. We provide an in-depth review of the key issues and trends in these areas, the challenges faced when reasoning and making decisions with real-time crowdsourced data (such as issues of information overload, "noise", misinformation, bias and trust), the core technologies and Open Geospatial Consortium (OGC) standards involved (Sensor Web Enablement and Open GeoSMS), as well as a few outstanding project implementation examples from around the world.


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Would you like fries with that?
Posted by johnm on February 11, 2004 at 11:30 AM PST
According to this EWeek article, Sun has a promotion through June, 2004 wherein a purchase of Sun's Java Studio Enterprise product subscription also gets you an AMD Opteron-based SunFire server.
The catch is that the subscription cost is $1500 per year with what looks like a 3 year commitment.
I do like the switch to focusing on the hardware as a support for the software.
Related Topics >>
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- johnm's blog
- 787 reads


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Archive for August, 2011
In Florida and most other states, where an employee quits his/her job, they are typically not entitled to recover unemployment benefits. The exception to this rule is where an employee quits based upon good cause attributable to the employer.
Believe it or not, in a case in Miami, a female employee quit her employment based upon the sexual harassment of her employer, and sought unemployment thereafter. Florida unemployment refused her unemployment benefits questioning whether or not she was sexually harassed because she did not go to the police or seek counseling. The employee claimed that she tolerated the actions of her employer for a while because she needed her job, but could not tolerate it any longer and quit.
The Third District Court of Appeal in Miami, thankfully, ruled that this employee was entitled to her unemployment benefits. The Court ruled, "Additionally, sexual harassment can continue for several years before the victim makes public her complaint . . . . Considering a job is usually a person's economic lifeline, the claimant's failure to contact outside authorities regarding her complaint cannot be called unreasonable or inherently improbable."
The case is 940 Lincoln Road Enterprises v. Margarita Hernandez.
If you are refused unemployment benefits by your employer or the unemployment office, seek the advice of an employment lawyer. There are many deadlines to be observed to protect your legal rights so don't let them slip by. Feel free to call Scott Behren and the Behren Law Firm with questions on your unemployment benefits.
Long time no blog, now that summer vacation is over its time to getting back to updating my readers on whats the latest and greatest in employment law issues. A fitness companies recent settlement with the EEOC, shows that sexual harassment of employees is bad and even worse is when you retaliate against them rather than attempt to remedy their complaints of discrimination and harassment.
Allstar Fitness, Seattle, has agreed to pay $150,000 to settle a sexual harassment and retaliation lawsuit with the U.S. Equal Employment Opportunity Commission (EEOC).
The agency claimed that a Latina janitorial worker who worked at two Allstar Fitness clubs in Seattle was repeatedly sexually assaulted by her immediate supervisor. The EEOC also said that the supervisor forced her to have sex with him on a regular basis and warned her to keep quiet about it.
When the worker told the supervisor not to harass her anymore, he fired her the next day, according to the EEOC investigation. After she reported the supervisor to the company's upper management, the EEOC and the worker claim that Allstar Fitness failed to investigate the matter and expressed disbelief in her allegations.
The EEOC filed the lawsuit in July 2010 on behalf of the 38-year-old worker, a mother of three.
EEOC District Director Michael Baldonado said the settlement will ensure that Allstar Fitness implements employee training, written workplace policies and a complaint procedure "to help prevent this from happening again."
"No one should be forced to choose between personal dignity and the paycheck that feeds your family," Baldonado said.
If you believe you have been subjected to sexual harassment in the workplace report it to your Human Resources Department or the EEOC. If the situation does not get fixed or if you suffer retaliation as a result, speak with a lawyer that handles employment law matters. Feel free to consult with the Behren Law Firm and Scott Behren on these types of issues.


text: photo courtesy of MSU Photo Sepp Jannotta [ Weed Sniffing Dogs Help Rid Mount Sentinel of Invasive Plant [AUDIO] By Peter Christian August 14, 2014 Dyer's woad is an invasive plant found in five Montana locations, one of which is on Missoula's iconic Mount Sentinel. Read More|Comment Category: Local News Tags: Dyer's Woad, Invasive Weed, Mt. Sentinel, Search Dogs, University of Montana Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


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Necklace, glass / lampworked glass / Hemalyke / imitation rhodium-finished steel, multicolored with copper-colored foil, 12mm round / 16x13mm oval / 61x37mm donut teardrop, 19 inches with lobster claw clasp and 2-inch extender chain. Sold individually.
Item Number: K11-3116JE
Dazzle your everyday style with a shimmering glass necklace. Lightweight, purple and black glass beads gravitate to a striking black glass focal piece, glistening with copper-colored foil. Colors can include purple, black, grey, clear and pink. In each lot of handcrafted items, colors, shapes and sizes may vary.
Restricted Shipping to:
More Information on Product Safety and Restrictions


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Create a beautiful foundation with Stella McCartney's lace-trimmed midnight-blue stretch-silk bra. Slip on this lightly padded style with the matching thong to complete the set.
Midnight-blue stretch-silk, lace trimLightly padded underwired cupsAdjustable shoulder straps, silver-tone designer tagHook fastenings at back 53% silk, 38% polyamide, 9% elastane; lace: 85% polyamide, 15% elastaneHand wash
Product code: 99666 - Need help? Contact us


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On March 28th, while on location in New York City, we had the opportunity to speak with Luke Rudkowski, founder of We Are Change, about his thoughts on 9/11 First Responder health issues. Luke and the other members of We Are Change NY regularly gather at Ground Zero to speak about a number of 9/11 related issues. One of those issues is the health care crisis which now faces tens of thousands of 9/11 First Responders.
There is no question that Luke Rudkowski is a passionate advocate for 9/11 First Responders and his organization has raised tens of thousands of dollars to benefit them. While considered "extreme" by some in his efforts to raise issues about 9/11 related issues, their is no doubt that Rudkowski has had a broad reaching effect through his activism. We Are Change has grown from a single small grassroots organization in New York to one with membership chapters across the United States and many foreign countries. Through their ongoing efforts to educate and inform the public at large, hundreds of thousands of people worldwide have learned about the health issues now facing 9/11 First Responders.
The excerpts of our interview above were shot just hours before Luke Rudkowski and two additional members of We Are Change were arrested for attempting to question NYC Mayor Bloomberg about his position on 9/11 First Responder health care and related legislation now pending before the Congress of the United States. Rudkowski is a regular contributing reporter to a number of web based media outlets and had intended to release his interview findings for broadcast on those outlets thereby reaching a potential audience of millions. For his efforts at exercising his First Amendment Rights, Rudkowski and the others were arrested on charges of criminal trespass and impersonating reporters.
The cameras and video evidence they had gathered to document their press related efforts were confiscated at the time of their arrest. You can find out more about Luke's arrest and what lead up to it by tuning into his Live Web cast at http://www.wearechange.org/ on Sunday, April 5th, at 4pm Eastern Time. Among several topics on the show, he plans to discuss the latest developments related to the March 28th arrest.We will also continue to follow this story and update regularly on new developments.


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(USA Today) -- It's finally happened.
A small island-hopping airline says it has begun charging passengers by weight, according to media reports from around the world.
The carrier is tiny Samoa Air, which flies turboprop flights within the Samoan islands.
As for the carrier's weight-based pay scheme, the BBC reports "passengers pay a fixed price per kilogram, which varies depending on the route length."
ABC News appears to have broken the report, though it says Samoa Air apparently introduced the practice in January.
"People who have been most pleasantly surprised are families, because we don't charge on the seat requirement even though a child is required to have a seat, we just weigh them," Samoa Air Chris Langton tells Australia's ABC News radio.
"So a family of maybe two adults and a couple of mid-sized kids and younger children can travel at considerably less than what they were being charged before," he adds, according to Australia Network News.
The Sydney Morning Herald reports that Samoa Air's "rates vary depending on the distance flown: from $1 per kilogram on the airline's shortest domestic route to about $4.16 per kilogram for travel between Samoa and American Samoa. Passengers are then weighed again on scales at the airport, to check that they weren't fibbing online."
One kilogram equals about 2.2 pounds.
As background, the Morning Herald notes "Samoa has a serious obesity problem and is often included in the top 10 countries for obesity levels."
CEO Langton says he hopes his airline's policy "has raised the awareness of weight" in Samoa.
Langston adds to ABC News that charging by weight helps address safety concerns for the company's small Britten and Cessna aircraft.
"Aeroplanes don't run on seats, they run on weight," he says to ABC News. "The smaller the aircraft you're in, the less variance you can accept in terms of the differences in weights between passengers."


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Application Information
Scholarship Overview
This scholarship is for African-American graduating seniors from Orrville High School in Ohio. To qualify for this scholarship, applicants must be attending an accredited college, university, business school, or trade school. Scholarship applications will be available in March through the Orrville High School Guidance Office.
How easy is it to apply?
Not too bad
This scholarship's application process may have items such as essays that could take a couple hours.
How much competition is there?
Relatively little!
This scholarship has a relatively low number of applicants.
Class Year: Is this you?
- High school senior
Home State: Is this you?
- Ohio
High School: Is this you?
- Orrville Digital Academy
- Orrville High School
Ethnicity: Is this you?
- African American


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|Use mini brioche tins to create a baker inspired Advent calendar.
- Rub on the numbers from 1 - 25 on the cardstock and use your 1 1/2 inch scrapbook hole punch to cut them all out.
- Use the spray adhesive to glue the numbers inside the brioche mini tins
- Glue the Magnets to the back of the tins
- Arrange the numbers of your Advent calendar on your refrigerator
- Place notes of directions where the treats or presents are located under each number


text: Link Ink: Inafune's New Fighting Robot, Murphy's Rejected Batman Pitch And Jodorowsky's Asteroid by Caleb Goellner September 4, 2013 Wednesday's links are all yours, after the cut. Read More Filed Under: Alejandro Jodorowsky, asteroids, Batman, Capcom, Hot Toys, I Am Street Fighter 25 Years of Inspiration, Keiji Inafune, Lego, Might No. 9, Mighty No 9, Mighty Number 9, Sean Murphy, Space Captain Harlock, Street Fighter Category: Culture, Link Ink Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


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|Minimal stimulation with simplified monitoring for in vitro fertilization.
MedLine Citation:
|PMID: 7795368 Owner: NLM Status: MEDLINE
|PURPOSE: This retrospective, descriptive study was designed to determine the effectiveness of using clomiphene citrate in relatively high daily doses (100, 150, and 200 mg) with simplified monitoring for in vitro fertilization in a private office and surgical center. The self-selected study population comprised 109 women who were 25-42 years old, including 26 women whose husbands had mild male-factor infertility. RESULTS: During January 1992 through December 1993, 165 stimulation cycles resulted in 137 egg retrievals, 24 clinical pregnancies (17.5%), and 20 viable pregnancies (14.5%). Cycles that could not be completed (28/165 or 16.9% of all cycles) involved luteinizing hormone surges, insufficient follicles, or low estradiol levels. There were no pregnancies in patients who were 40 years or older or who received 200 mg daily doses of clomiphene citrate. The viable pregnancy rate among patients with male factor infertility was 7.7% (2/26). For non-male-factor infertility patients who were younger than 40, the viable pregnancy rate was 17.6% (18/102). CONCLUSION: The simplified monitoring method did not appear to compromise the results.
|J B Massey; P E Ingargiola; M J Tucker; D E Mitchell-Leef; G Wright
Related Documents :
|19944418 - Clomiphene citrate plus tamoxifen versus laparoscopic ovarian drilling in women with cl...
2680618 - Validity of the bioself 110 fertility indicator.
6796438 - The role of ultrasound in ovulation induction: a critical appraisal.
2245828 - Late luteal administration of the antiprogesterone ru486 in normal women: effects on th...
8065668 - The association of maternal social class with maternal diet and the dimensions of babie...
7778588 - Smith-lemli-opitz syndrome: prenatal diagnosis by quantification of cholesterol precurs...
Publication Detail:
|Type: Comparative Study; Journal Article
Journal Detail:
|Title: Journal of assisted reproduction and genetics Volume: 11 ISSN: 1058-0468 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 1994 Aug
Date Detail:
|Created Date: 1995-07-31 Completed Date: 1995-07-31 Revised Date: 2008-03-18
Medline Journal Info:
|Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: UNITED STATES
Other Details:
|Languages: eng Pagination: 353-8 Citation Subset: IM
|Reproductive Biology Associates, Atlanta, Georgia 30342, USA.
Export Citation:
|APA/MLA Format Download EndNote Download BibTex
|MeSH Terms
Biological Markers / urine
Chorionic Gonadotropin / therapeutic use
Clomiphene / therapeutic use*
Dose-Response Relationship, Drug
Embryo Transfer
Fertilization in Vitro*
Infertility, Male / physiopathology
Luteinizing Hormone / urine*
Menstrual Cycle
Monitoring, Physiologic / methods*
Ovarian Follicle / ultrasonography
Pregnancy Outcome
Private Practice
Retrospective Studies
Self Care
Spermatozoa / physiology
Reg. No./Substance:
|0/Biological Markers; 0/Chorionic Gonadotropin; 9002-67-9/Luteinizing Hormone; 911-45-5/Clomiphene
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The screening of embryonic viability in early asymptomatic pregnancy by a single endosonographic sca...
Next Document: The effect of dam's strain on the intrauterine craniofacial growth of mouse fetuses.


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Kiko Goats
Savanna Goats
Commercial Herd
Herd Sires
Goats for Sale
About Us
Fellow Goat Breeders
Web Design
Today's Landlord sale AAA+ hublot replica watches uk, best quality breitling replica watches watches for sale, all of them are 58% off. You shouldn't missing! Welcome!
Welcome to W3 & Hogan Ranch Website. W3 Ranch has moved their goats to Southeast Kansas and went into partnership with Michael & Venessa Hogan. We are located just south of Moline, KS.
W3 Ranch meat goat operation consists of the development of three separated herds: full blood Savanna Goats, full blood Kiko Goats, plus a percentage and commercial herd. Kiko and Savanna full blood and percentage goats for sale. All of our goats have the option of papers either as pure bred or percentage.
We strive to develop a strong doe herd base with exceptional maternal instincts, parasite resistance, and early kid growth. We have chosen the Kiko and Savanna breeds as they have the history and genetics for these traits. W3 Ranch is a forage based operation with multiple pastures for herd rotation. Loose minerals are provided free choice and the herd is provided supplement during inclement weather. Worming and veterinarian services are provided on a as needed bases.
Our commercial herd is made up of Kiko/Boer cross bred to full blood Kiko and Savanna bucks. We have Percentage goats for sale at all times.
If you are looking for Savanna Goats for Sale, please see our sales page or fill out our contact form. Our Savanna goats are muscular, fully developed goats, and adapt well to a variety of climates.
Savanna Goat
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FELONY DWI - POTSDAM - Canton-based state police charged Thomas R. Logan, 57, of Waddington with a felony count of driving while intoxicated and use of a vehicle without an interlock device and ticketed her for failure to keep right following an incident at 8:28 p.m. Saturday in the town of Potsdam. He was placed under arrest at 8:45 p.m. on the Buck Road in the town of Madrid.
ONE INJURED - BANGOR - Malone-based state police said one person was injured in a one-vehicle accident at 11 a.m. Saturday on Taylor Road, near state Route 11B, in the town of Bangor. Troopers said the vehicle was being operated by Alexis S. Chapman, 17, of Dickinson Center.
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Glendale Arts kicks off a month-long film series tonight and along with providing a family-friendly event, it also will help the needy.
Through a partnership with Tegan Summer Productions, Glendale Arts will show four American classics at the Alex Theatre. The first film is "The Sound of Music." It screens at 7 p.m. tonight.
Subsequent titles are "E.T.: The Extra Terrestrial — 25th Anniversary Screening," at 7 p.m. Aug. 15; "The Princess Bride," at 7 p.m. Aug. 22; and "The Neverending Story," at 7 p.m. Aug. 29.
Patrons who bring canned goods to any of the screenings will receive a coupon good for $5 off tickets to any of the Glendale Pops Orchestra concerts. The canned goods will go to the Glendale Salvation Army Food Bank.
Tickets for each screening are $12 for adults and $8.50 for children and seniors, plus a $2.50 per-ticket facility/restoration fee. Tickets can be purchased at www.AlexTheatre.org, or in person at the Americana at Brand concierge desk in the Grand Lobby.
Purchase tickets to the entire series and get one screening free. Tickets to the full series are available at www.alextheatre.org/patrons/purchasesubscription-gafilms2012, or in person at the Americana at Brand concierge desk in the Grand Lobby.
USC Trojan Guild prepares for new year
USC Trojan Guild of Los Angeles officers are preparing for a new year under the theme, "TGLA Looking to the Future While Reflecting on the Past." Leading the group is President Rosalee Perchersky.
Serving with her are President-elect Christine Offiesh; Patricia Dowling and Patti Poon, sharing first vice-president – programs; Jean Ann Holbrook, second vice-president, sales products; Jean Getchell and Sandi Hampar, sharing third vice-president, scholarships; Marilyn Wallace and Margie Moore, sharing fourth vice-president, membership; Mary Indenbaum, recording secretary; Gloria Phillips, of Glendale, corresponding secretary; Jolene Irwin, treasurer; and Janet Eddy, of Glendale, parliamentarian. Others serving as officers are Marilyn O'Driscoll of Glendale, product sales treasurer; Carol Thueson of Glendale, Reflections; and Leslie Lilly, of Burbank, product account treasurer.
Trojan Guild has been an active women's philanthropic support group at USC since 1960. Members have raised funds for many scholarships while gaining friendships and intellectual enrichment through speakers from many USC departments. Any woman who has attended USC and is 30 years old or older, with a continuing interest in the university, is invited to apply for membership. For information, contact Marilyn Wallace, membership chairwoman, at firstname.lastname@example.com.
Church celebrates 100 years
The First Church of Christ, Scientist will celebrate 100 years in Glendale with a public lecture and potluck on Aug. 26 at the church, 1320 N. Brand Blvd.
Following the 1:30 p.m. potluck Mark Swinney, a Christian Science lecturer, will give a talk on "The Healing Effect on Your Prayers" at 2 p.m. In the church auditorium.
Eighteen followers of Christian Science gathered on March 31, 1912 to incorporate the First Church of Christ, Scientist in Glendale. The church moved to several locations around town, including the church at 500 S. Central Ave., built by members in 1926, which currently houses an Armenian Apostolic church. The church on Brand opened its doors in 1990. For more information, call (818) 242-1493.
JOYCE RUDOLPH can be reached at firstname.lastname@example.com.
Film series benefits needy
USC Trojan Guild board members ready to start the new year are, from left, Glendale residents Marilyn ODriscoll, product sales treasurer; Carol Thueson, Reflections; Janet Eddy, past president; Gloria Phillips, corresponding secretary; and Burbank resident Leslie Lilly, product account treasurer. (Courtesy of the USC Trojan Guild / August 7, 2012)


text:
|Accession Numbers: EG10357 (EcoCyc), b4122, ECK4115
Subunit composition of
fumarase B = [FumB]2
fumarase B monomer = FumB
Fumarase B (FumB) is one of three fumarase isozymes participating in the TCA cycle. FumB belongs to the class I fumarases; like FumA, it is a homodimeric 4Fe-4S cluster-containing protein [Woods88, vanVugtLussenbu13]. Fumarase B is required for anaerobic growth on D-tartrate [Kim07] and appears to be involved in biofilm formation [Herzberg06].
The cell adapts to changing environmental oxygen conditions by utilizing different isozymes. Both FumA and FumB contain iron-sulfur centers; exposure to oxidative agents such as superoxide results in damage to the metal cofactor and loss of enzyme activity [Flint93a]. Although FumB was previously reported to have a higher affinity for malate than for fumarate [Woods88], recent kinetic data using a purified enzyme have shown it to be similar to FumA [vanVugtLussenbu13]. FumB is thought to function as an alternative enzyme during anaerobiosis [Woods87, Tseng01]. In contrast, FumC is an iron-independent enzyme and is insensitive to oxidative damage [Flint94]. FumC is made by the cells primarily as a backup enzyme if the FumA or FumB enzymes are damaged by reactive oxygen species. [Tseng97, Liochev93, Tseng01, Lara06]
Expression of all three fumarase genes is anaerobically controlled. Expression of fumB gene is four fold elevated under anaerobic cell growth conditions versus aerobic conditions [Tseng97]. In contrast, fumA expression is highest only during aerobic growth and where fumC is only weakly expressed. When cells encounter oxidative stress conditions, fumC gene expression is then significantly induced by the SoxRS regulatory system [Park95]. The aerobic/anaerobic transcriptional regulators ArcA and Fnr function to repress fumA as well as fumC gene expression under anaerobic conditions.
Overexpression of fumB complements the fumA1 mutation [Guest83, Guest85] and a fumAC deletion [Henson87]. The expression level of fumB is highest under anaerobic growth on glycerol and fumarate [Woods87]. fumB expression is regulated in response to oxygen, iron and heme availability [Gruer94, Tseng97] and increases 9-fold upon deletion of tqsA, which increases biofilm formation [Herzberg06].
Citations: [Bell89, Gray66, Guest92, Overton06]
Gene Citations: [AboAmer04, Golby98, Bell89]
Locations: cytosol
|Map Position: [4,343,703 <- 4,345,349] (93.62 centisomes, 337°)
|Length: 1647 bp / 548 aa
Molecular Weight of Polypeptide: 60.105 kD (from nucleotide sequence), 61.0 kD (experimental) [Guest85 ]
Molecular Weight of Multimer: 120.0 kD (experimental) [vanVugtLussenbu13]
Isozyme Sequence Similarity:
fumarase A monomer: YES
Unification Links: ASAP:ABE-0013501 , CGSC:18289 , EchoBASE:EB0352 , EcoGene:EG10357 , EcoliWiki:b4122 , OU-Microarray:b4122 , PortEco:fumB , PR:PRO_000022735 , Pride:P14407 , Protein Model Portal:P14407 , RefSeq:NP_418546 , RegulonDB:EG10357 , SMR:P14407 , String:511145.b4122 , UniProt:P14407
Relationship Links: InterPro:IN-FAMILY:IPR004646 , InterPro:IN-FAMILY:IPR004647 , InterPro:IN-FAMILY:IPR011167 , InterPro:IN-FAMILY:IPR020557 , Pfam:IN-FAMILY:PF05681 , Pfam:IN-FAMILY:PF05683 , Prosite:IN-FAMILY:PS00163
In Paralogous Gene Group: 318 (3 members) , 484 (3 members)
GO Terms:
|Biological Process:
|GO:0006099 - tricarboxylic acid cycle
GO:0006974 - cellular response to DNA damage stimulus [Khil02]
GO:0042710 - biofilm formation [Herzberg06]
GO:0006091 - generation of precursor metabolites and energy [GOA01a]
|Molecular Function:
|GO:0004333 - fumarate hydratase activity
[GOA01, GOA01a, vanVugtLussenbu13, Flint93a]
GO:0042803 - protein homodimerization activity [vanVugtLussenbu13]
GO:0047808 - D(-)-tartrate dehydratase activity [GOA01, vanVugtLussenbu13, Kim07]
GO:0051539 - 4 iron, 4 sulfur cluster binding [UniProtGOA11a, vanVugtLussenbu13]
GO:0003824 - catalytic activity [GOA01a]
GO:0016829 - lyase activity [UniProtGOA11a, GOA01a]
GO:0016836 - hydro-lyase activity [GOA01a]
GO:0046872 - metal ion binding [UniProtGOA11a]
GO:0051536 - iron-sulfur cluster binding [UniProtGOA11a]
|Cellular Component:
|GO:0005829 - cytosol [Lasserre06]
|MultiFun Terms:
|metabolism → energy metabolism, carbon → fermentation
|metabolism → energy metabolism, carbon → TCA cycle
Essentiality data for fumB knockouts:
|Growth Medium
|Growth Observations
|LB enriched
|Yes [Gerdes03, Comment 1]
|LB Lennox
|Yes [Baba06, Comment 2]
|M9 medium with 1% glycerol
|Yes [Joyce06, Comment 3]
|MOPS medium with 0.4% glucose
|Yes [Baba06, Comment 2]
Yes [Feist07, Comment 4]
Last-Curated 25-Feb-2013 by Keseler I , SRI International
Enzymatic reaction of: fumarase B
Synonyms: fumarate hydratase B
EC Number: 184.108.40.206
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction of enzyme catalysis.
This reaction is reversible. [vanVugtLussenbu13]
In Pathways: superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass , superpathway of glyoxylate bypass and TCA , TCA cycle I (prokaryotic) , mixed acid fermentation
Purification of fumarase B from E. coli W has been described [Yumoto88].
The midpoint potential of FumB at pH 8 is -283 mV [vanVugtLussenbu13].
Inhibitors (Unknown Mechanism): superoxide [Flint93a, Korshunov02]
Kinetic Parameters:
Enzymatic reaction of: D-tartrate dehydratase (fumarase B)
EC Number: 126.96.36.199
D-tartrate <=> oxaloacetate + H2O
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Reversibility of this reaction is unspecified.
Kinetic Parameters:
|Feature Class
Gene Local Context (not to scale):
Transcription Units:
10/20/97 Gene b4122 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG10357; confirmed by SwissProt match.
AboAmer04: Abo-Amer AE, Munn J, Jackson K, Aktas M, Golby P, Kelly DJ, Andrews SC (2004). "DNA interaction and phosphotransfer of the C4-dicarboxylate-responsive DcuS-DcuR two-component regulatory system from Escherichia coli." J Bacteriol 186(6);1879-89. PMID: 14996819
Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554
Bell89: Bell PJ, Andrews SC, Sivak MN, Guest JR (1989). "Nucleotide sequence of the FNR-regulated fumarase gene (fumB) of Escherichia coli K-12." J Bacteriol 1989;171(6);3494-503. PMID: 2656658
Feist07: Feist AM, Henry CS, Reed JL, Krummenacker M, Joyce AR, Karp PD, Broadbelt LJ, Hatzimanikatis V, Palsson BO (2007). "A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information." Mol Syst Biol 3;121. PMID: 17593909
Flint93a: Flint DH, Tuminello JF, Emptage MH (1993). "The inactivation of Fe-S cluster containing hydro-lyases by superoxide." J Biol Chem 268(30);22369-76. PMID: 8226748
Flint94: Flint DH (1994). "Initial kinetic and mechanistic characterization of Escherichia coli fumarase A." Arch Biochem Biophys 1994;311(2);509-16. PMID: 8203917
Gerdes03: Gerdes SY, Scholle MD, Campbell JW, Balazsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabasi AL, Oltvai ZN, Osterman AL (2003). "Experimental determination and system level analysis of essential genes in Escherichia coli MG1655." J Bacteriol 185(19);5673-84. PMID: 13129938
GOA01: GOA, MGI (2001). "Gene Ontology annotation based on Enzyme Commission mapping." Genomics 74;121-128.
GOA01a: GOA, DDB, FB, MGI, ZFIN (2001). "Gene Ontology annotation through association of InterPro records with GO terms."
Golby98: Golby P, Kelly DJ, Guest JR, Andrews SC (1998). "Transcriptional regulation and organization of the dcuA and dcuB genes, encoding homologous anaerobic C4-dicarboxylate transporters in Escherichia coli." J Bacteriol 1998;180(24);6586-96. PMID: 9852003
Gray66: Gray CT, Wimpenny JW, Mossman MR (1966). "Regulation of metabolism in facultative bacteria. II. Effects of aerobiosis, anaerobiosis and nutrition on the formation of Krebs cycle enzymes in Escherichia coli." Biochim Biophys Acta 117(1);33-41. PMID: 5330664
Gruer94: Gruer MJ, Guest JR (1994). "Two genetically-distinct and differentially-regulated aconitases (AcnA and AcnB) in Escherichia coli." Microbiology 1994;140 ( Pt 10);2531-41. PMID: 8000525
Guest83: Guest JR, Roberts RE (1983). "Cloning, mapping, and expression of the fumarase gene of Escherichia coli K-12." J Bacteriol 153(2);588-96. PMID: 6296045
Guest85: Guest JR, Miles JS, Roberts RE, Woods SA (1985). "The fumarase genes of Escherichia coli: location of the fumB gene and discovery of a new gene (fumC)." J Gen Microbiol 131(11);2971-84. PMID: 3005475
Guest92: Guest JR, Russell GC (1992). "Complexes and complexities of the citric acid cycle in Escherichia coli." Curr Top Cell Regul 33;231-47. PMID: 1499335
Henson87: Henson JM, Blake NK, Marek LE (1987). "The isolation of fumB mutants of Escherichia coli." J Gen Microbiol 133(9);2631-8. PMID: 2834509
Herzberg06: Herzberg M, Kaye IK, Peti W, Wood TK (2006). "YdgG (TqsA) controls biofilm formation in Escherichia coli K-12 through autoinducer 2 transport." J Bacteriol 188(2);587-98. PMID: 16385049
Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394
Khil02: Khil PP, Camerini-Otero RD (2002). "Over 1000 genes are involved in the DNA damage response of Escherichia coli." Mol Microbiol 44(1);89-105. PMID: 11967071
Kim07: Kim OB, Lux S, Unden G (2007). "Anaerobic growth of Escherichia coli on D-tartrate depends on the fumarate carrier DcuB and fumarase, rather than the L-tartrate carrier TtdT and L-tartrate dehydratase." Arch Microbiol 188(6);583-9. PMID: 17643228
Korshunov02: Korshunov SS, Imlay JA (2002). "A potential role for periplasmic superoxide dismutase in blocking the penetration of external superoxide into the cytosol of Gram-negative bacteria." Mol Microbiol 43(1);95-106. PMID: 11849539
Lara06: Lara AR, Leal L, Flores N, Gosset G, Bolivar F, Ramirez OT (2006). "Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system." Biotechnol Bioeng 93(2);372-85. PMID: 16187334
Lasserre06: Lasserre JP, Beyne E, Pyndiah S, Lapaillerie D, Claverol S, Bonneu M (2006). "A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis." Electrophoresis 27(16);3306-21. PMID: 16858726
Liochev93: Liochev SI, Fridovich I (1993). "Modulation of the fumarases of Escherichia coli in response to oxidative stress." Arch Biochem Biophys 301(2);379-84. PMID: 8460946
Overton06: Overton TW, Griffiths L, Patel MD, Hobman JL, Penn CW, Cole JA, Constantinidou C (2006). "Microarray analysis of gene regulation by oxygen, nitrate, nitrite, FNR, NarL and NarP during anaerobic growth of Escherichia coli: new insights into microbial physiology." Biochem Soc Trans 34(Pt 1);104-7. PMID: 16417494
Park95: Park SJ, Gunsalus RP (1995). "Oxygen, iron, carbon, and superoxide control of the fumarase fumA and fumC genes of Escherichia coli: role of the arcA, fnr, and soxR gene products." J Bacteriol 1995;177(21);6255-62. PMID: 7592392
Tseng01: Tseng CP, Yu CC, Lin HH, Chang CY, Kuo JT (2001). "Oxygen- and growth rate-dependent regulation of Escherichia coli fumarase (FumA, FumB, and FumC) activity." J Bacteriol 2001;183(2);461-7. PMID: 11133938
Tseng97: Tseng CP (1997). "Regulation of fumarase (fumB) gene expression in Escherichia coli in response to oxygen, iron and heme availability: role of the arcA, fur, and hemA gene products." FEMS Microbiol Lett 157(1);67-72. PMID: 9418241
UniProt10a: UniProt Consortium (2010). "UniProt version 2010-11 released on 2010-11-02 00:00:00." Database.
UniProt15: UniProt Consortium (2015). "UniProt version 2015-01 released on 2015-01-16 00:00:00." Database.
UniProtGOA11a: UniProt-GOA (2011). "Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries."
vanVugtLussenbu13: van Vugt-Lussenburg BM, van der Weel L, Hagen WR, Hagedoorn PL (2013). "Biochemical Similarities and Differences between the Catalytic [4Fe-4S] Cluster Containing Fumarases FumA and FumB from Escherichia coli." PLoS One 8(2);e55549. PMID: 23405168
Woods87: Woods SA, Guest JR (1987). "Differential roles of the Escherichia coli fumarases and fnr-dependent expression of fumarase B and aspartase." FEMS Microbiol Lett 48:219-24.
Woods88: Woods SA, Schwartzbach SD, Guest JR (1988). "Two biochemically distinct classes of fumarase in Escherichia coli." Biochim Biophys Acta 1988;954(1);14-26. PMID: 3282546
Yumoto88: Yumoto N, Tokushige M (1988). "Characterization of multiple fumarase proteins in Escherichia coli." Biochem Biophys Res Commun 1988;153(3);1236-43. PMID: 3291870
Zhang09: Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu CF, Grishin NV, Zhao Y (2009). "Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli." Mol Cell Proteomics 8(2);215-25. PMID: 18723842
Baez13a: Baez A, Shiloach J (2013). "Escherichia coli avoids high dissolved oxygen stress by activation of SoxRS and manganese-superoxide dismutase." Microb Cell Fact 12;23. PMID: 23497217
Chen12: Chen YP, Lin HH, Yang CD, Huang SH, Tseng CP (2012). "Regulatory role of cAMP receptor protein over Escherichia coli fumarase genes." J Microbiol 50(3);426-33. PMID: 22752906
Janausch04: Janausch IG, Garcia-Moreno I, Lehnen D, Zeuner Y, Unden G (2004). "Phosphorylation and DNA binding of the regulator DcuR of the fumarate-responsive two-component system DcuSR of Escherichia coli." Microbiology 150(Pt 4);877-83. PMID: 15073297
Kim09a: Kim OB, Reimann J, Lukas H, Schumacher U, Grimpo J, Dunnwald P, Unden G (2009). "Regulation of tartrate metabolism by TtdR and relation to the DcuS-DcuR-regulated C4-dicarboxylate metabolism of Escherichia coli." Microbiology 155(Pt 11);3632-40. PMID: 19661178
Salmon05: Salmon KA, Hung SP, Steffen NR, Krupp R, Baldi P, Hatfield GW, Gunsalus RP (2005). "Global gene expression profiling in Escherichia coli K12: effects of oxygen availability and ArcA." J Biol Chem 280(15);15084-96. PMID: 15699038
Scheu12: Scheu PD, Witan J, Rauschmeier M, Graf S, Liao YF, Ebert-Jung A, Basche T, Erker W, Unden G (2012). "CitA/CitB two-component system regulating citrate fermentation in Escherichia coli and its relation to the DcuS/DcuR system in vivo." J Bacteriol 194(3);636-45. PMID: 22101843
Spiro91: Spiro S, Guest JR (1991). "Adaptive responses to oxygen limitation in Escherichia coli." Trends Biochem Sci 1991;16(8);310-4. PMID: 1957353
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LOWVILLE — The Lewis County Sheriff's Office arrested a Lowville man at 6:38 Sunday morning after an alleged domestic dispute.
Oscar J. Medina, 31, of 5965 Waters Road, hid from deputies and when located provided a false name and date of birth, deputies said.
Mr. Medina was charged with criminal possession of a narcotic drug, heroin, with intent to sell, a Class B felony, two misdemeanor counts of criminal use of drug paraphernalia in the second degree, three counts of endangering the welfare of a child, misdemeanor false personation, second-degree obstructing governmental administration and unlawful possession of marijuana.
He was sent to the Lewis County jail on $10,000 cash bail or $20,000 bond.
The Lowville Police Department and K9 Wyman aided in the arrest.
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Conclusion of our series of posts about your natural gifts for drawing…
By combining the four natural gifts that you already have with some traditional art skills, you will be quickly able to draw. You don't need to enter any mysterious altered state of consciousness, or study arduously for years in order to be able to draw a likeness. All you have to do is believe you can and know how to combine the four natural gifts that you already have using appropriate drawing exercises.
Of course, for many artists drawing also forms the basis for researching and planning a painting. If you intend starting out your journey of self discovery through art, drawing is great skill to have in your 'kitbag', both as an art in itself and as part of the painting process.
The Complete Drawing and Painting Certificate Art Course contains exercises specifically designed to help you develop your four natural gifts for drawing, and then combine them to form the whole skill, whilst at the same developing some foundation painting and colour mixing skills.
Ready to start refining your natural gifts for Drawing?
Enrol or feel free to ask us a question.
Cindy Wider
Latest posts by Cindy Wider (see all)
- Colored Pencil Portrait – Kara's Butterfly by Tannis Trydal - December 18, 2014
- Around the World Creative Blog Hop - November 10, 2014
- How To Overcome Artists Block and Procrastination Once and For All! - August 6, 2014


text: The styling of our professional racing gear is available in this street design, complete with a glove-like fit. Self-extinguishing split suede conforms to anatomical contours, shielding the foot in comfort. The padded collar includes an adjustable ankle strap, and the high-grip sole gets a firm bite on surfaces while still allowing tactile response on the pedal. Moisture wicking textiles help maintain an optimal foot climate.


text:
Would it be possible to retro-fit SGI dials support
into freeglut? Contrary to some of the comments I have
seen, there are people who really _do_ need SGI dials
support (especially in the scientific community).
There would be a lot of X-ray crystallographers that
would *really* appreciate SGI dials support in freeglut!
Thanks - Stephen
Logged In: NO
Agreed. My understanding is that support for SGI dials was actually
removed from freeglut, so perhaps adding it back in would not be *too*
much of a problem. In any event, our group (which consists of several
dozen users) relies heavily on the SGI dials, and we have already
begun the conversion process from SGI/IRIX boxes to Debian Gnu/Linux
boxes. We have already encountered this problem (the dials work fine
on our RedHat 9 boxes, which we are eagar to re-image with Debian, but
do not work on our Debian boxes with the freeglut 2.2.0-8 .deb
package). Thanks very much.
Steve Lane
System Administrator
Doudna Lab
Biomolecular Structure and Mechanism Group
UC Berkeley
drsteve at rna-dot-berkeley-dot-edu
John F. Fay
Logged In: YES
I would be delighted to have this done, but I don't know of
anybody who has SGI dials who would be able to test this
out for us. We are going to have a release sometime fairly
soon--this follow-up is part of my run-up to creating a release
version--and if you want support for SGI dials now would be
the time to get it in.
- John F. Fay


text:
Hrm, well, I think that varies a bit...one thread of postmodernism was certainly the "Collage City"/Jane Jacobs line (that eventually leads to new urbanism) where there's an active project of trying to save the city, move away from the monumental and embrace the fabric - that seems like a project with social ambition to me. Or in the Bofill posted above, maybe those images don't quite get it across but there was a clear desire to give "palaces to the people," quoting history specifically to create something that the residents would recognize as grand and honorific.
― Doctor Casino, Saturday, 3 January 2009 17:39 (6 years ago) Permalink
I used to think that the only thing unifying about postmodernist thought (or the only thing postmodernists "believe in") is a rejection of enlightenment ideals, but that's obviously glossing over a lot. For me, it is easy to view Modernism as truly beautiful as applied to one building, but equally as easy to view it as one-note as an archtectural movement, and even potentially oppressive. One manifestation of post-modernism's "social concern" (lol) would be multivalence, and the presentation of a variety (I was going to say "of aesthetic sensibilities", but I think "variety" is enough).
― rox qua rox (roxymuzak), Saturday, 3 January 2009 21:37 (6 years ago) Permalink
Yes - and then you have even more severe examples like Lucien Kroll (I think it's Kroll) where the architect's office has an open door, serving soda to the people who are going to live in the building and inviting them to make design decisions. Or Leon Krier, who believed that industrial building practice was so dehumanizing that it was better not to build, so as to avoid participating in the alienation of the worker. Postmodernism was a big umbrella, for a while there - I mean if you read an early edition of Jencks's Language of Post-Modern Architecture it really seems exciting. By the fifth or sixth edition all the photos look like the late Graves and the jig is up.
― Doctor Casino, Monday, 5 January 2009 02:33 (6 years ago) Permalink
Oh, and I finally posted my pics of WORKac's Public Farm 1. On the previous thread, I wrote:
"re: P.F.1 - Yeah, it was great - particularly in light of the kind of stuff that typically wins. They seem to feel that the committee or jury or whoever realized they were getting really tired of atmospheric projects. "We could have won last year, but not ten years ago." It was refreshing to me as a living example of Dutch-ness here on our shores (they both worked at OMA) by architects young enough that you could imagine "hey, that could be me!" So that's always going to be encouraging. But I also loved how much it was filled in with fun little gimmicks and gizmos - the periscope, the audio and video of working farms, the chicken coop...it was cool."
Extended, archi-nerd ramblings here.
― Doctor Casino, Monday, 5 January 2009 02:37 (6 years ago) Permalink
Jencks's Language of Post-Modern Architecture
This is what got me into architecture in the first place!
― roxymuzak, Monday, 5 January 2009 02:51 (6 years ago) Permalink
Haha! Just read it last year after it seemed to keep coming up. Good stuff, I read a later-ish edition that was starting to really drag by the end though. Needed a fresh edit I think, got repetitious, but as a showcase of just neat stuff and ideas the first half is essential. The "Death of Modern Architecture" chapter is classic.
― Doctor Casino, Monday, 5 January 2009 02:53 (6 years ago) Permalink
I still remember where I was when I read that.
― roxymuzak, Monday, 5 January 2009 02:55 (6 years ago) Permalink
...don't leave us hanging!
― Doctor Casino, Monday, 5 January 2009 02:56 (6 years ago) Permalink
Well, it's not exciting in re: this thread, but I was in Nashville sitting on a couch at Douglas Corners waiting to go play a show. It's just a vivid memory because I enjoyed the reading so much.
― roxymuzak, Monday, 5 January 2009 02:59 (6 years ago) Permalink
Know just what you mean - although in these grad school years there's pretty much one of three places I'm ever reading anything.
― Doctor Casino, Monday, 5 January 2009 03:02 (6 years ago) Permalink
i got the other thread locked, i hope no one objects to this? i think it's just confusing having 2 threads being revived and it's more of a rolling discussion thread at this point so it makes sense. if you do i'm sure we can get it reopened.
last post on the previous thread was hyggeligt helpfully linking us to SpaceInvading
thanks for that, it's actually a great link and saves quite a bit of trawling around various different blogs although it still has links to those blogs for more description, which is cool.
― jed_, Thursday, 15 January 2009 01:17 (6 years ago) Permalink
Sou Fujimoto Architects' Wooden House. love it or hate it, you've never seen anything like it.
― jed_, Thursday, 15 January 2009 01:23 (6 years ago) Permalink
― jed_, Thursday, 15 January 2009 01:26 (6 years ago) Permalink
I think anybody who ever had blocks as a kid has seen something like it.
― El Tomboto, Thursday, 15 January 2009 01:26 (6 years ago) Permalink
ha, i was just about to add a similar caveat.
― jed_, Thursday, 15 January 2009 01:28 (6 years ago) Permalink
BLOOMFRAME®The BLOOMFRAME® breaks out of the 2-dimensional facade to add to the usable space in this innovative design by Hofman Dujardin Architects.
prototype that is expected to go into actual production early this year:
Bloomframe® is an innovative window frame that can be transformed into a balcony allowing an increase in usable space with minimal intervention.
Bloomframe® offers the user a flexible living environment. By opening the window frame, it is possible to walk out through the facade and to enjoy a comfortable balcony. The dynamic balcony enables adding outdoor space to compact apartments in urban high-rise areas.
The Bloomframe® balcony can be operated automatically with a simple push of the button. The system includes provisions to guarantee collapse safety during opening and closing.
The drive consists of an rpm-controlled electric motor that operates the balcony at two points via an auto-braking reduction (drop safety). The movement is transferred by tie rods from these linear guides.
The fully open position is limited mechanically, which guarantees optimum safety of the converted balcony. The application of a combined powered/mechanical movement makes the system user-friendly and easy to open and close for everyone.
― jed_, Thursday, 15 January 2009 01:34 (6 years ago) Permalink
I don't think I really understand the Bloomframe? It creates a not very attractive half-window when closed and doesn't seem to offer any advantages over a regular building other than potentially animating the building facade more - and you have to keep your patio furniture inside when you're not using it. I think I'd like it more with a glass bottom panel since it'll be up 80% of the time.
― Tina Fey's narrative bonsai (I DIED), Thursday, 15 January 2009 01:49 (6 years ago) Permalink
SpaceInvading is one of my favorite things about 2009
I'm glad so many designers are doing these weird 3D circulation intensive tiny houses/follies, but I'd sure like to see some upholstery in them or at least first aid kits for the inevitable bloody heads.
― Tina Fey's narrative bonsai (I DIED), Thursday, 15 January 2009 01:52 (6 years ago) Permalink
bloomframe would be cooler if the patio furniture folded out with it, like a pop-up book.
― El Tomboto, Thursday, 15 January 2009 01:53 (6 years ago) Permalink
I'd like that! Or if the patio furniture was permanently secured to it so it stuck out from the inside wall of your house when closed.
― Tina Fey's narrative bonsai (I DIED), Thursday, 15 January 2009 01:56 (6 years ago) Permalink
and if it wasn't the color of an HVAC component.
― El Tomboto, Thursday, 15 January 2009 01:56 (6 years ago) Permalink
haha yeah it looks like a big access panel.
― Tina Fey's narrative bonsai (I DIED), Thursday, 15 January 2009 01:57 (6 years ago) Permalink
well, i love it. obviously it doesn't have to be khaki/grey, it can be any colour, i would imagine. the bottom half could possibly be glass but people have vertigo. white steel is fine by me. also you just sit on a chair that you have in your lounge, or whatever. i wouldn't imagine you would have specific furniture for it unless it was some cheap folding deck chair you could keep in a cupboard?
― jed_, Thursday, 15 January 2009 02:21 (6 years ago) Permalink
I'm getting one
― cozwn, Thursday, 15 January 2009 02:24 (6 years ago) Permalink
me too, on m4ryhi11 road end.
― jed_, Thursday, 15 January 2009 02:26 (6 years ago) Permalink
Yay new thread!
Doctor Casino, though you are a medical man with a gambling problem so far as I can tell from login name, I do like your flickr. It has been very good recently.
Which edition is the better one to start with? Is this book the same one under a different name?
I like the Bloomframe! I think it could be a real boon to new apartments. I loathe buildings like the blocky ones upthread. They are just grotesque monoliths hammering the pedestrian down with sheer BLOCK COLOURS. Just awful.
― hyggeligt, Thursday, 15 January 2009 10:30 (6 years ago) Permalink
hi architects
looking at going on a solo field trip in march. probably europe. have been thinking of istanbul but that's just because I'd like to go there. where would you go? for like six days or so. money is an object but where would you go?
― conrad, Thursday, 15 January 2009 13:38 (6 years ago) Permalink
Where to begin! I've only really done Western Europe (no further east than Vienna) and with huge swaths of untouched territory in there. My gut says you kind of can't screw it up in terms of travel, life experience, food, all that kind of stuff - are you trying to see the maximum amount of architecture possible or just have a great trip where you also see some fab buildings?
hyggeligt - thanks! It'll be dormant again for a while, I am now entering my last studio at school and am busy, plus obviously not traveling.
― Doctor Casino, Thursday, 15 January 2009 14:05 (6 years ago) Permalink
re: That 2002 Jencks - it certainly SOUNDS like a revised edition of the original - Now rewritten and with two new chapters, the seventh edition brings the history up to date with the latest twists in the narrative, and the turn to a new complexity in architecture. Rewritten with new chapters didn't really serve the previous editions all that well - just started to feel aimless and tacked-on-to. But enough time had passed that I could imagine the 2002 volume being interesting, and I appreciate anything that calls out and explores the fundamentally postmodern qualities of 90s computer projects (Greg Lynn et al). Dunno... haven't read the new bits so I dunno if it's worth it or not.
― Doctor Casino, Thursday, 15 January 2009 14:08 (6 years ago) Permalink
Is okay, jealousy at fancy locations was eating in to my soul anyway. Could do with the spiritual break! (xpost)
Thanks for that Dr Cas, will chance it and see when I'm flush.
― hyggeligt, Thursday, 15 January 2009 14:10 (6 years ago) Permalink
I should have said - have been to budapest, vienna, brno, prague, zurich, basel, madrid, barcelona, rome, florence, naples, berlin, munich, paris, krakow, amsterdam, rotterdam, brussels and others and places in between like leon in spain and vals in switzerland etc. and some UK stuff (I'm in scotland)
so, having never been up to copenhagen/oslo/stockholm/gothenberg/helsinki/tallinn/riga...I'm interested but don't have a ready idea of what's the best destination. not limited to europe other than in terms of the money issue
was looking at v cheap flights to oslo but hostels there seem on the expensive side. cheap flights and accommodation for gdansk but...I don't know if there's that much to see and can't seem to find good info
great trip w/ fab buildings would be fine but as much architecture as poss would be more justifiable in a way
― conrad, Thursday, 15 January 2009 14:33 (6 years ago) Permalink
that's a lot of places. are you in glasgow?
i hear Lisbon is lovely (and cheap on easyjet)
― jed_, Thursday, 15 January 2009 14:36 (6 years ago) Permalink
what about croatia? supposed to be gorgeous.
― jed_, Thursday, 15 January 2009 14:39 (6 years ago) Permalink
in glasgow yes (I mentioned conrad to you at a party on new years morning but it was early and late so I don't blame you for forgetting!)
had thought about lisbon and about porto too but was looking for something direct hoping to minimise cost and travel time
marseille? venice??
I should have found a better thread to ask this stuff as I obviously haven't been thinking about enough architects
― conrad, Thursday, 15 January 2009 14:56 (6 years ago) Permalink
I love the Bloomframe and I would sit in a Panton chair in it.
― Sickamous Mouthall (Scik Mouthy), Thursday, 15 January 2009 14:59 (6 years ago) Permalink
ah yes, i remember conrad.
― jed_, Thursday, 15 January 2009 15:02 (6 years ago) Permalink
venice yeah, go there. march is a good time to go, i think. i want to go back because i was only there for a day and a half but i loved it.
marseille i remember being quite rough but it's good to go and see the unité.
― jed_, Thursday, 15 January 2009 15:06 (6 years ago) Permalink
I would say Copenhagen is well worth the visit!
― hyggeligt, Thursday, 15 January 2009 15:07 (6 years ago) Permalink
Copenhagen is rich with stuff - see the Flickr stream and sets of user seier_seier_seier. Really interested in going myself. Here's an email seier wrote me when I was considering a trip:
difficult question, copenhagen in two days...
copenhagen is pretty expensive (as is the rest of scandinavia) especially when coming from the u.s., so I'll recommend you a youth hostel which opened recently in a central office tower (not a tower by american standards, but by danish...you'll see).
the same site mentions an even more central hostel opening in april. might be worth checking out:
helsinki and stockholm has some OK hostels too, I would look for the hostel in the olympic stadium in helsinki and the hostel on an old boat in stockholm, if I were you.
stockholm, btw, is my favourite city in scandinavia - it is beautiful, has great nature, landscape, architecture, and wom...its a nice place.
[re copenhagen:]
now, what to see....if the weather is good, I would go for places rather than buildings, in bad weather (of which we have plenty) vice versa...
places to see would be:
strandvejen north of copenhagen, the coastal road leading through the well off suburbs to the north, great on a summers day, will take you past lots of fine sites, including good buildings like arne jacobsen in klampenborg:
and utzon's related housing projects in fredensborg and elsinore:
there is a fine renaissance castle in elsinore which inspired shakespeare a few years ago...can't miss it.
the louisiana museum of modern art in humlebæk is a hugely influential building from the fifties, taking the formal out of the museum and putting in nature instead. lots of contemporary architects has named this building as an inspiration, including nouvel, foster and herzog + de meuron.
oh, hang on, from elsinore the thing to do would be to take the ferry to sweden (30 minutes) and drive to klippan to see the lewerentz church
now, that's a whole day in a rented car, so maybe you'll prefer to stay in the city...
there's christiania free town, www.flickr.com/photos/seier/1244185274/in/set-72157603843053592/, a good place to see in the evening, food and bars and a very different street scene.
should the sun shine, the island of amager, formerly known as the ass hole of copenhagen, is seeing some very interesting change these years...on a sunny afternoon, former working class and industrial neighbourhood "islands brygge" is full of young copenhageners sunbathing and swimming in the habour. it is really lively and some of the gir...MVRDV has one of their best buildings nearby:
further east, on the amager coast facing sweden, is another interesting industrial area undergoing radical change. surrounded by large scale infrastructure like a wind mill park, the airport and the bridge to sweden is a new beach, a huge piece of landscaping very popular with the locals already.
and there's the old town, of course, lots of cafés and shops and the odd arne jacobsen building...
if you are just going for the buildings, I would not miss:
- the foyer of the national bank, arne jacobsen 1961-1978. central copenhagen.- bagsværd church, utzon. 20 minutes by train from copenhagen.- klippan church, klippan, sweden. about 2 hours by train, I think.
― Doctor Casino, Thursday, 15 January 2009 17:30 (6 years ago) Permalink
thanks for that - going to weigh up copenhagen further but it would involve two flights. venice seems like the right choice for a lot of reasons and might be possible w/ some juggling but oslo currently £11 return for four nights is going to be hard to beat even though a cheap hostel has yet to make itself known
― conrad, Thursday, 15 January 2009 17:51 (6 years ago) Permalink
Very true. Try and end up at Ordrupgaard. Recently reopened with new wing. Bakken in the Dyrhaven nearby is trippy and good fun (I also think it might be the world's oldest fairground, I spent far too much time there growing up as it was free in unlike Tivoli).
Merely a legend alas. The crown jewels are there so well worth a look.
Yes. Avoid visiting if there's a rehang because the permanent collection isn't huge for the trip involved. Another good gallery is the Glyptotek near Radhuspladset. Carlsberg money built and filled it. Lovely stuff.
Sadly not any more. They've closed down the drug stalls on pusher street and basically developers are moving in. Very sad now. I was there recently and was followed by four police officers. I am obviously sketchy looking.
A harbour tour is also a good idea. That way you get to see the Black Diamon of the royal library from the water and get closer to the new opera house. Rosenborg slot is a baroque palace in the centre of town near Norreport. It was one of Christian IV's vanity projects and well worth seeing.
Check his shots of Venice for more inspiration Conrad. Again, thanks to Doctor Casino I have been following for the past few months. It is a great stream!
― hyggeligt, Thursday, 15 January 2009 20:40 (6 years ago) Permalink
I have some Venice and surroundings here: http://www.flickr.com/photos/doctorcasino/sets/72157601373054872/
― Doctor Casino, Thursday, 15 January 2009 21:17 (6 years ago) Permalink
this is my favorite thing in the world at the moment:
by Levitate Architects
― jed_, Friday, 16 January 2009 14:58 (6 years ago) Permalink
haha I thought that first shot was an elevation and was like "whaaaaaaat?"
That design is a really fantastic thing.
― Tina Fey's narrative bonsai (I DIED), Friday, 16 January 2009 15:02 (6 years ago) Permalink
haha, did the same thing!
― Doctor Casino, Friday, 16 January 2009 15:09 (6 years ago) Permalink
that stairbookcase is insanely beautiful: the top image reminds me of this mad dream i used to have as a child about a rabbit-warren library with walls made of earth ane books.
― king lame (c sharp major), Friday, 16 January 2009 15:32 (6 years ago) Permalink
i posted that stairbookcase to the What do your books look like? thread on ILB and stet said:
That looks great, but is functionally crap: you'll kick dirt into the books as you climb, and the ones at eye level are furthest from your eyes.
which kinda boggled me.
― jed_, Friday, 16 January 2009 15:43 (6 years ago) Permalink
well yeah but it's more of a limited space solution than it is a most perfectly accessible behind glass eye level book collection solution.
― Tina Fey's narrative bonsai (I DIED), Friday, 16 January 2009 15:58 (6 years ago) Permalink
dezeen maybe needs to work on the color balance for those video interviews they're doing - ross lovegrove looks like a DEMON! I was going to post the pic here but it's actually too frightening so I'll link instead.
― Tina Fey's narrative bonsai (I DIED), Friday, 16 January 2009 16:43 (6 years ago) Permalink
are the cutout designs on the front advertising free wifi?
kidding, really like it. the lighting (the actual fixtures, that is) looks cool
― mh, Tuesday, 21 January 2014 22:39 (1 year ago) Permalink
all the lights over the bar are 1970s dutch and german ceramic shades, having an electrician who can rewire anything is invaluable
― Sadly, 99.99 percent of sheeple will never wake up (I DIED), Friday, 24 January 2014 17:10 (1 year ago) Permalink
oh that looks lovely, i died. so much wood can be overload but the interiors look terrific.
― mustread guy (schlump), Friday, 24 January 2014 17:49 (1 year ago) Permalink
thanks - we ended up using 5 or 6 different kinds of wood in a variety of oiled/stained/painted finishes to keep it interesting
― Sadly, 99.99 percent of sheeple will never wake up (I DIED), Friday, 24 January 2014 18:04 (1 year ago) Permalink
i ate there when i was in DC! on the lower level. delicious ramen, really cool space, and i loved the exterior metal cutouts
― hug niceman (psychgawsple), Friday, 24 January 2014 18:14 (1 year ago) Permalink
Wow, great work, I DIED! Keep 'em coming I say!
― Doctor Casino, Wednesday, 29 January 2014 01:42 (1 year ago) Permalink
re: Williams and Tsien, I think it's a fair point, that they may have been irresponsible as architects. One of my professors summarized it yesterday as, it was a modest institution and they did not provide them with a modest building. And I think that's a criticism well-taken, but... that institution no longer occupies the building, and I feel like MOMA's decision to demolish or not demolish it could be discussed on its own terms. To me it first of all reads as a huge missed opportunity (they could do really cool stuff with it - or even make it the centerpiece of their ensemble, since they actually don't have an iconic facade, not really).
― Doctor Casino, Wednesday, 29 January 2014 01:45 (1 year ago) Permalink
was in the Viking Art programme on tv yesterday.
there are bigger examples of stave churches but i like the concise blackness of the one in Urnes
― koogs, Sunday, 16 March 2014 12:37 (1 year ago) Permalink
Wow, yes please.
― Doctor Casino, Sunday, 16 March 2014 14:34 (1 year ago) Permalink
was one of the churches allegedly burnt down by black metallers.
― koogs, Monday, 17 March 2014 12:18 (1 year ago) Permalink
I love looking at and thinking about those.
― an enormous bolus of flatulence (jon /via/ chi 2.0), Monday, 17 March 2014 16:03 (1 year ago) Permalink
Hadid's office really doubling down in the asshole stakes: http://www.dezeen.com/2014/03/18/architecture-not-art-patrik-schumacher-venice-architecturebiennale-rant/
― Sadly, 99.99 percent of sheeple will never wake up (I DIED), Tuesday, 18 March 2014 16:42 (1 year ago) Permalink
saw him once on a panel his every utterance was either cipherful or inane
― conrad, Tuesday, 18 March 2014 17:20 (1 year ago) Permalink
(i love that that page has "Latest Staircases" rather than, say, sideboob or cellulite.)
― koogs, Tuesday, 18 March 2014 17:22 (1 year ago) Permalink
((oh, spoke too soon))
― koogs, Tuesday, 18 March 2014 17:29 (1 year ago) Permalink
major fire at Charles Rennie Mackintosh's Glasgow School of Art :(
― Sadly, 99.99 percent of sheeple will never wake up (I DIED), Friday, 23 May 2014 13:20 (1 year ago) Permalink
Ughhhhhh. That is really depressing. Majority of the building (including archives) is apparently okay - but the library,the one absolute must-see that I've been saving for some future trip to Scotland, is completely destroyed.
― Doctor Casino, Monday, 26 May 2014 14:09 (1 year ago) Permalink
people familiar with NYC, this may be a dumb question, but what is the building with all of the angled planes in the background of this shot? various google searches have turned up nothing, i keep being led back to the Hearst Tower
― ƋППṍӮɨ∏ğڵșěᶉᶇдM℮ (jon /via/ chi 2.0), Thursday, 18 December 2014 03:34 (9 months ago) Permalink
― controversial but fabulous (I DIED), Thursday, 18 December 2014 03:59 (9 months ago) Permalink
Ah, thank you!
― ƋППṍӮɨ∏ğڵșěᶉᶇдM℮ (jon /via/ chi 2.0), Thursday, 18 December 2014 05:43 (9 months ago) Permalink
To add emphasis to this older structure, OMA carefully clad the building's entire exterior in 24-karat gold leaf. Only the glass of the windows was left exposed."It was actually a last minute inspiration, to find a way to give value to a seemingly mundane and simple element," said Koolhaas. "But we discovered that gold is actually a cheap cladding material compared to traditional claddings like marble and even paint."
"It was actually a last minute inspiration, to find a way to give value to a seemingly mundane and simple element," said Koolhaas. "But we discovered that gold is actually a cheap cladding material compared to traditional claddings like marble and even paint."
c'mon man
― controversial but fabulous (I DIED), Monday, 4 May 2015 12:29 (5 months ago) Permalink
― Doctor Casino, Monday, 4 May 2015 16:20 (5 months ago) Permalink
― controversial but fabulous (I DIED), Tuesday, 4 August 2015 15:18 (2 months ago) Permalink
omg lol
― Gorefest Frump (Doctor Casino), Tuesday, 4 August 2015 15:57 (2 months ago) Permalink


text:
This is a call for entries to the young creative talent competition in China. The prize, a bright career future starting at the global ad agencies. The 6th "Liu Yue Long Men" Creative Competition is open for submissions this month, and the country's creative blood is getting hot.
Our humble studio is surrounded by W+K, Mindshare, JWT, Ogilvy, McCann etc, and our local pink salon (hooker shop). We have not yet been lucky enough to experience such a brilliant sight of cleavages. Next time we are in their offices we have to look harder!
My mother often asked me " Why can't you just take your MA to get a job in companies like a big ad agency or Google or Apple, standing on the giant's shoulder you will see a bright and promising future!"
"But I want to be a small giant mama!!"
Well the true reason is little me just don't have cleavage like that…sigh…


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Issue 10.02 | Feb 2002
this article for free.
Strange, short, and supercool
Experimental films are often just eye candy - nice to look at, short on substance. But Brit moviemaker Richard Fenwick's digital video series, RND# - for "random number" - is something you can really bite into.
His 100-episode project (7 of which are in the can) is an attempt to understand how technology affects our lives and, depending on your interpretation, how it dismantles or sustains us.
The latest 90-second installment, 23 Content Provider, mixes hyperkinetic computer-generated graphics and video. Its linear plot follows a blinking digital transmission from satellite to television, where the mishmash of animated blueprints morphs into a clip from a bizarre English soap opera.
While RND# lives up to its name (the episodes are being released out of sequence, for example), the series will come together in six or so years when it's finally complete.
- Tank Menzies
View online at www.ideo.com/rnd.
Previous Story: Reengineering the Everglades
Next Story: Flesh and Machines: How Robots Will Change Us, by Rodney A. Brooks


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What do you think of the
Roxy Waterfall Pullover Hoodie - Women's
? Share a...
Industrial Warmth Hoodie
If you are looking to keep warm this is the hoodie for you. The fleece lining makes it perfect for fall and winter temperatures. After a couple of washes, the inside still has that new sweat shirt feel (the softness you never want to lose). Perfect for those with a long torso as it is long and rests on your hips as opposed to on top of them. If you have hips I would recommend going a size up, because the waist band does not give even with wear. My favorite part: I get compliments every time I through it on.
roxy waterfall pullover hoodie
sooo soft! it fits great! I love how its a longer fit. I got this sweatshirt in gray and im going to get the same one in aster blue. overall this is my new favorite sweater!


text:
Distribution of Births by Gestational Age, United States, 1990 and 2005
The distribution of births by gestational age changed between 1990 and 2005. The percentage of preterm births (<37 completed weeks of gestation) increased 20%, from 10.6% to 12.7%; the percentage of births at 37--39 weeks of gestation also increased, from 41.4% to 53.5%, a 29% increase. In contrast, the percentage of infants born at 40 weeks and especially 41 weeks of gestation declined (15% and 43%, respectively).
Data Source: National Vital Statistics System. Births: preliminary data for 2005. Available at:
Centers for Disease Control and Prevention. QuickStats: Distribution of Births, by Gestational Age –United States. MMWR 2007;56:14(344). Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5614a7.htm.
Additional Information and Resources
March of Dimes Resources
Prematurity Campaign*
More information about premature birth and the March of Dimes prematurity campaign.
Share Your Story* (Spanish language online community also available)
Virtual community for parents with a baby in a neonatal intensive care unit.
This Web site provides a wealth of national, state, and local perinatal statistics.
Preterm Labor and Birth
More information from the National Institute of Child Health and Human Development.
Premature Babies
The National Library of Medicine provides links to the latest news and research on preterm birth.
National Prematurity Awareness Month
More than a half million babies in the United States—that's 1 in every 8—are born premature each year.
Healthy Pregnancy
Learn how to be healthy (before, during, and after pregnancy) and give your baby a healthy start to life.
Podcast About Premature Births (For Healthcare Providers), 10/6/2006
Listen To This Podcast... (6:33)
Podcast About Premature Births (For Consumers), 10/6/2006
Listen To This Podcast... (5:19)
CDC's Division of Reproductive Health
Promotes optimal reproductive and infant health. CDC scientists and their partners are collaborating with states, university researchers and partners in health care to understand why preterm births occur, and what can done to prevent prematurity.
CDC's National Center on Birth Defects and Developmental Disabilities
Promotes the health of babies, children, and adults, and enhances the potential for full, productive living.
*Links to non-federal organizations are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the federal government, and none should be inferred. CDC is not responsible for the content of the individual organization Web pages found at these links.
Page last reviewed: November 21, 2007
Page last updated: November 21, 2007
Content source:MMWR and Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion
Content owner: Office of the Associate Director for Communication, Division of News and Electronic Media
URL for this page: http://www.cdc.gov/datastatistics/2007/births/


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Past Aviation Mysteries
The partially reconstructed wreckage of the Trans World Airlines... News PhotoAccidents and Disasters,Ashburn,Horizontal,Politics,Rebuilding,Sitting,USA,WreckPhotographer Alex WongCollection: Getty Images News 2013 Getty ImagesASHBURN, VA - JULY 02: The partially reconstructed wreckage of the Trans World Airlines Flight 800 (TWA 800) sits in a hanger at the National Transportation Safety Board (NTSB) Training Center July 2, 2013 in Ashburn, Virginia. TWA 800 flight exploded shortly after takeoff on July 17, 1996 from John F. Kennedy International Airport, killing all 230 onboard and crashing into the Atlantic Ocean. Today, members of the media were invited back to review the wreckage and the details of the NTSB investigation. (Photo by Alex Wong/Getty Images)


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Guest Categories
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Parlay Group
Overview: The Parlay Group was formed to develop open, technology-independent application programming interfaces (APIs) that enabled the development of applications that operate across multiple networking-platform environments. The Parlay Group integrated intelligent network (IN) services with IT applications via a secure, measured, and billable interface. The Parlay Group's goals included: defining, establishing, and supporting a common specification for industry-standard APIs; facilitating the production of test suites and reference code in multiple technologies that enable developers to create related products and services that operate across wireless, Internet-protocol (IP), and public-switched networks; providing an environment in which member companies can approve suggested revisions and enhancements that evolve the initial specifications; making appropriate submissions to established agencies and bodies with the purpose of ratifying these specifications as international standards; and providing a forum in which users can meet with developers and providers of products and services to identify requirements for interoperability and general usability. The Parlay Group also sought to educate the business and consumer communities about APIs through publications, trade show demonstrations, seminars, and other programs. *Dissolved in 2007
Specifications: Not available
IPR Policy: Not available
Current Status: Inactive


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Nahan bus accident leaves 13 dead, three critical
At least 13 tourists were killed and three others were left critically injured when a bus driver lost control of his vehicle while driving uphill in Himachal Pradesh's Nahan. The bus reportedly skidded off the road and rolled down a gorge leaving another 40 passengers injured.
Sub-Divisional Magistrate (SDM), Nahan, Jyoti Rana, said, "The bus carrying 56 passengers, which had most of the tourists from Saharanpur in Uttar Pradesh rolled down a gorge in HP's Sirmaur district when it was headed back to UP from Renuka. The bus was at Modraghat, which is 10 kms from Renuka, when it fell into 250 ft deep gorge."
"40 passengers are under treatment in Nahan, while 3 who were seriously injured have been shifted to PGI Chandigarh. The locals helped in rescuing those who were alive and also pulled out dead bodies from the debris."
The locals said that the authorities and ambulance were called, but they didn't reach the spot on time and a lot of lives could have been saved if the required help had reached the spot at the right time.
(Posted on 17-06-2014)
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