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Powerskin Battery Case for iPhone 5 Review
Cases for the Phone 5 abound, but when a battery recharging system is built in, the field narrows considerably. There's often a trade-off between protection and convenience, feature accessibility and weight that must be taken into account. For a battery-enabled iPhone case to be truly useful, it must circumvent the problems, not just play to its strengths. The PowerSkin for iPhone 5 manages to do all this.
I wanted a case to protect the iPhone from inadvertent disaster — but not so bulky that It wouldn't fit in a pocket. The PowerSkin for iPhone 5 is made from a smooth silicone composite that is stiff but somewhat flexible. First I pulled out the lightning connector inside its bottom edge and connected it to the iPhone. Then I inserted the phone's bottom into the case and worked the sides around it. Finally I pulled the top of the case away from the phone and then seated the top. The screen and Home button remain uncovered. The bit of lip around the edges of the case keep the screen from touching a surface if laid face down too.
A cutout in the side of the case let the ringer tab peek through and the cutout in the back accommodates the camera lens and LED. The volume touch buttons are covered though. A micro-USB port at the bottom side of the case plugs in for charging and syncing. This is one of the highlights of the PowerSkin: most battery cases for the iPhone 5 can charge both the internal battery and the iPhone when plugged into USB but can not sync the phone. This means you have to remove the case to connect to iTunes. Having to remove the case is counter-productive in that one might not bother to put it back on right away — and that's when Murphy's law kicks in. But other than having to use a micro-USB cable to connect the PowerSkin to a USB port, the iPhone 5 will function in tandem with iTunes in the normal manner.
The bottom of the case has a hole for the headphone jack. An extension cable is supplied and hangs outside — this makes the case awkward to use if left on and being moved around during the course of a day has the potential for damaging the headphone connection or the cable itself. But there's another issue in that soemtimes the cable doesn't transmit the commands from a pair of Apple or Apple-compatible earbuds. So the earbuds can be used to listen to, but taking a call, playing music or adjusting volume must all be done from the iPhone when this happens. I found you have to jiggle the plug of the earbuds in the extension cable socket to be sure — although it usually caused some hissing noise to occur momentarily.
I've found that my iPhone loses power quickly when I'm accessing 4G for data (this often happens when I'm walking the aisles of trade shows). This is the reason I wanted a battery case in the first place, so I could do a quick recharge while on the go. But I also found that the weight of the case is nothing when compared to battery cases I've used in the past — my wife, who has another brand battery case on her iPhone, didn't at first believe that there was a battery there at all due to the flatness of the case's back and the lack of weight. I had to press the recessed tab on the back to light up the blue LEDS (showing the battery strength) to prove I wasn't making this up. The tab turns the battery power on/off with a long press.
1500 mAH battery extends talk time by up to 6.5 hours and music time up to 32 hours One piece design provides shock absorption
Battery tab can be activated if back of case pushed against a hard surface
Marshal Rosenthal
Marshal Rosenthal is a Los Angeles-based freelance writer and journalist specializing in technology, consumer electronics and pop culture.


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A friend of mine is hosting a conference in New Orleans in late October, and he's looking for a chef to run a cooking class or conduct a demo for the attendees. I don't know many details, but I assume that between budget and the short time frame, the usual, more famous suspects won't fit the bill, so he's looking for someone who's got local cred, but could use some broader exposure -- think along the lines of Emeril in 1991, right after he opened his first place. Is there someone in the city that fits that bill today?
Who's up and coming in NOLA?
Started by Dave the Cook , Sep 20 2012 02:27 PM
6 replies to this topic
Posted 20 September 2012 - 02:27 PM
Dave Scantland
Executive director
eG Ethics signatory
Eat more chicken skin.
Posted 21 September 2012 - 10:19 AM
Phillip Lopez (Root) is probably the hottest thing going right now. Probably too hot for your needs. Dominique Macquet is a close second, (Dominique's on Magazine & Tamarind), when the former opens he will proabbly move up a notch. Quan Tran is his chef de cusine at Tamarind, and might fit the bill. In the lesser known but hungry there is Mat Farmer (Apolline). Also Matt Murphy (Irish House), he just won a chopped episode. Personally, I really like Michael Costantini's food. he was behind Saitsuma's dinner servcie, and is now running their Maple Street location. Of the various new locales in the bywater his food was head and shoulders ahead of the rest. Fianlly, I should mention that Frank Brightsen teaches a class once a week on Bayou Rd., so no reason to think he wouldn't be interested. Another old timer would be Kevin Vizard, he is great with people. Finally, Nathanial Zimet, might be a good choice. He is a nice guy. Hope that helps.
Posted 21 September 2012 - 10:26 AM
All of the above, plus Michael Doyle from Maurepas Foods in the Bywater.
Posted 21 September 2012 - 10:49 AM
Michael Doyle was the first name I thought of....but I have not seen him present, so I can say if he'd wow the crowd on that front.
Bouillie: eating in south Louisiana
Bouillie: eating in south Louisiana
Posted 21 September 2012 - 10:58 AM
He is on youtube:
Posted 21 September 2012 - 10:59 AM
Check that out. Talk about a link. I didn't even do anything special.
Posted 21 September 2012 - 03:49 PM
Yeah. He's definitely passionate about what he does.

subset: commoncrawl


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Stocks lose opening gains after some unexpected bad news about our nation's factories. Joan Doniger has the latest money news.
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October 6, 2015
WASHINGTON (AP) - The Federal Reserve says it has granted a request by the country's last two major investment banks, Goldman
Sachs and Morgan Stanley, to change their status to bank holding
The Fed announced late Sunday that it has approved the request of the two investment banks. The change in status will allow them to create commercial banks that will be able to take deposits, bolstering the resources of both institutions.
The change continues the biggest restructuring on Wall Street
since the Great Depression.
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At first glance, a Toyota Sienna minivan commercial is both cute and funny. A guy in his late 30's gives several young children a test ride. The kids make various demands of their driver, including picking up a dog named "Bob." They respond rather abruptly when the driver asks a question while they are watching the in-vehicle DVD system. As the minivan pulls into the dealership parking lot, one young girl demands, "Now we'll test the red one." By the end of the commercial, many parents ...
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Rare $0.75/2 Nestle Crunch Bars Coupon = FREE at Rite Aid (11/22-11/24)
This Hip2Save.com Deal was hand-posted on Wednesday, November 14th, 2012 at 5:13 pm.
Yay! Head on over to coupons.com to print a new, and rare $0.75/2 Nestle Crunch Bars 1.55 oz. coupon under zip code 77477.
To easily print this coupon, follow these simple directions:
* Head on over to Coupons.com
* Click on the "Local Coupons" tab (located towards the top of the site)
* Enter the zip code 77477 in the box to the upper left
* Then click back on this link to quickly locate the coupon.
* That's it! Now go get to printing! :D
Use this coupon to score FREE Nestle Crunch Bars during Rite Aid's Black Friday Sale (11/22-11/24)! Here's how…
Hershey's, Mars, Nestle or Wrigley's Single Serve Candy Bars 3/$2
Buy 6 Nestle Crunch Bars 3/$2
Total = $4
Use 3 $0.75/2 Nestle Crunch Bars 1.55 oz. coupons found here
Pay $1.75
Get a $1 +Up Reward when you buy 3 (limit 4 offers)
Final Cost FREE + $0.25 Money Maker! Great stocking stuffers!
Keep in mind that not all stores are open on Thanksgiving Day, see your local store for details.
(Thanks, Hot Coupons Crazy Savings and How 2 Coupon!)
10 Hip Readers Commented
thanks collin!!
There's also the B2G1 Milky Way coupons – not quite as good a deal, but I like Milky Ways a whole lot better!
I didn't know they still sold Crunch. Haven't seen it in my RA in Queens, NY.
I think we have to pay .75 instead of 1.75
You will pay $1.75 out of pocket and receive two $1 +Up rewards.
I wish there was a way to delete comment…I just reread mine and thought the wording might have come across as rude! I wanted to say my math came out the same as Collin's and thought you might not have noticed that you receive two +Ups from the deal.
it's ok Beth. Thanks for correction :)
I printed one coupon from the link and one from Swagbucks. Both say that I am at my print limit after only one. Is there any way to get a third coupon without a second computer?
The Crunch candy bars are not part of the 3 for $2, get $1 +UP back sale. They ring up as 99 cents each and no $1 +UP is given.


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My Life With Books will be on a summer sabbatical and will return in October 2013.
Thank you for stopping by.
Thank you for stopping by.
Wednesday, October 19, 2011
Wishing on Wednesday
Posted by My Life With Books - Jennifer K Jovus at 10/19/2011 07:00:00 AM
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The Harvard men and women's track teams closed out their regular season this weekend, taking to the track against Ancient Eight foes Princeton and Yale on Saturday at the HYP meet in New Haven, Conn.
Despite coming off impressive showings at the Beantown Invitational on Feb. 4, the Crimson could not improve upon last year's pair of second-place HYP finishes, as the Tigers took first on both the men's and women's side.
Princeton continued its strong season, racking up victories on both sides, to post totals of 114 points for the men and 90.5 points for the women, in comparison to Harvard's 36 and 41.5 for the men's and women's sides, respectively.
"We went out and gave a good effort, but Princeton brought their game," captain Claire Richardson said. "The Tigers are always tough competitors, and we really wanted to beat them and make them uncomfortable on top of the Ivies. We did our best, but we still have a ways to go."
Nevertheless, Crimson coach Jason Saretsky seemed pleased with the result.
"The team took a big step forward in preparation for the Championships in two weeks," Saretsky said.
Despite the disappointing overall result, Harvard's weekend was punctuated by impressive performances by a talented class of freshmen, led by former Ivy Rookies of the Week Dustin Brode on the men's side and Christina Twicken on the women's side.
In the HYP meet, Brode placed second in the shot put with a throw of 16.81 meters, nearing his personal best of 17.00. Twicken, along with fellow freshman Meisha Brooks, led a 1-2 finish in the women's 400, crossing the line in 56.69. The two would team up again later in the day, with juniors Magda Roback and Shannon Conway, to win the 4x400 in 3:46.10.
Freshman Alysha Johnson joined the party, placing second in the women's shot put with a throw of 14.32 meters, a personal best that Saretsky called "a standout performance."
Sophomore teammate Shannon Watt followed Johnson in second. Back on the men's side, freshman Kobi Rex tied for second in the high jump at 1.94 meters.
"I feel like everyone is in the same mind set. We're all working hard, and hoping it will pay off in two weeks," Johnson said.
The performances of the freshmen this weekend also earned the respect of their upperclassmen teammates.
"The freshmen class works really hard," Richardson said. "The team loves them, they fit in and put up results on the track. It's definitely great to have them with the program."
Sophomore Mary Hirst won the women's high jump with a jump of 1.60 meters while classmate Oliva Weekes placed second in the triple jump (11.52m) and third in the long jump (5.47m) to continue a successful season. Claire Richardson took second in the 3000 with a time of 9:39.08 to close out the day.
Youth might have been a recurring theme, but Harvard's upperclassmen were sure to represent the Crimson on the podium as well.
Read more in SportsNo. 2 Yale Handily Defeats Harvard
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SPORTS BRIEF: Track and Field Uses Meet as Opportunity To Prepare for HepsWith the annual Heptagonal Championship only four days away, Sunday's USATF New England Championships at Harvard's Gordon Indoor Track provided a perfect opportunity for members of the Crimson's track and field teams to get one more race under their belt.


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Xolile Mngeni Sentenced In Anni Dewani Murder Trial
Vinod Hindocha, father of murdered Anni Dwani appears at the Cape... ニュース写真カエリチャ,ケープタウン,コリレ・ムゲニ,タクシー,ハイジャック,ハネムーン,バケーション,南アフリカ共和国,宣告,有事,殺人,殺人被害者,法,法廷,法律制度,父親,犯罪,犯罪者,登場,縦長,英国文化,被告人,裁判,裁判所,西ケープ州,観光客,証人,運転手Photographer Gallo ImagesCollection: Getty Images News 2012 Gallo Images (PTY) LTDCAPE TOWN, SOUTH AFRICA - SEPTEMBER 3: (SOUTH AFRICA OUT) Vinod Hindocha, father of murdered Anni Dwani appears at the Cape Town High Court, on September 3, 2012 in Cape Town, South Africa. He is attending the trial of Xolile Mngeni, who is accused of being involved in the murder of Anni. The deceased's husband Shrien Dewani remains in Britain fighting extradition as he faces accusations of allegedly plotting her murder. (Photo by Nasief Manie/Foto24/Gallo Images/Getty Images)


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Reach tens of thousands of people instantly by advertising with Ekklesia. Find out more
The UK government's culture secretary, Maria Miller, gave a rather faltering performance on BBC Radio 4's flagship 'Today' programme this morning, answering questions -- or, rather, trying to avoid them -- about the Marriage (Same-Sex Couples) Bill.
Marriage. What's it all about, then? In a sermon marking the wedding of two established friends of Ekklesia, Simon Barrow looks at the spiritual and social embeddedness which means that, in Bonhoeffer's words, "It is not your love that sustains the marriage, but from now on, the marriage that sustains your love."
The Christian thinktank Ekklesia says that the new 'Equal Love Campaign', with legal challenges aimed at securing the right to same-sex marriage and heterosexual civil partnerships, highlight once more the "long overdue" need to overhaul the system of marriage law in the UK.
Some hardline pressure groups within the church are sucking marriage into a narrow religious ghetto, associating it with suburban 1950s curtain-twitching, thus making it even less popular than it is now, says Giles Fraser.
Wedding fairs, guides and web advisers are the latest ways of trying to get more people to marry in church


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I have seen many people on KW hating on "fake" accounts which are people who hide there real identity and some people saying that they aren't fake and that there pics are real. I would like to point out that the people with the "fake" accounts are trying to protect themselves and they are trying to stay safe online. But other's like to take risks and they put on Real pictures of themselves. I think a real fake would be someone who would be taking the risk but instead of having the real picture as there avatar, they hide it in there pictures and they would do whatever they can to hide it and make it private, and the avatar instead is a picture of someone else.
For any of you who is in a situation where someone is a fake and it bothers you, There is a very simple trick you can perform, Instructions below:
- Right click on the image
- Copy image location
- Head over to Google images
-Scroll over to the camera icon and click it
-In the box put in the location
If the results come up with nothing, It proves that the person is Real but if the results does get some duplicates of the same image that will raise some red flags immediately
here welcome to: forums > random > say anything > how to spot a fake
here welcome to: forums > random > say anything > how to spot a fake


text: Keith Loving | IBDB: The official source for Broadway Information IBDB: The official source for Broadway Information Official Broadway League sites: - sites - broadway.org broadwayleague.com broadwayfanclub.com kidsnightonbroadway.com stagespecs.org tonyawards.com Quick Search For: In This Category: All Show People/Org. Theatre Season Keith Loving Performer Male See Also: City Rhythm Band Productions ProductionsDate of ProductionsBarry Manilow on Broadway[Special, Concert, Original] Also Starring: City Rhythm Band [Performer]Dec 21, 1976 - Jan 02, 1977 Find out where Keith Loving and are credited together © 2001-2015, The Broadway League, All Rights Reserved. (Copyright and Disclaimer)


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Brent Batten: Sequester fix taps into FAA fund backing Collier projects
The money being used by the FAA to keep air traffic controllers on the job is being pulled from the pot that funds airport improvements such as those planned for Marco Island and Immokalee. But the two projects and the controversy that surrounds them will likely go on.
Chris Curry, executive director of the Collier County Airport Authority, says the federal money has already been set aside for design and engineering for runway rehabilitation at the two airports. "All we're doing now is drawing down the funds that have we've been allocated," he said.
The design and engineering for the two projects is about 30 percent complete. The Immokalee design work carries a cost of about $760,000 while the Marco design is costing about $650,000. Each project is 90 percent funded by the FAA with state and local governments splitting the rest.
Last week Congress passed the Reducing Flight Delays Act of 2013. It allows Secretary of Transportation Ray LaHood to transfer as much as $253 million from money set aside for airport construction and repair to keep air traffic controllers from being furloughed, as had been required by budget sequestration.
When those furloughs began taking effect, flight delays ensued.
The act passed last week deals with fiscal year 2013, which ends Sept. 30.
Any threat to the Marco and Immokalee projects would come in 2014, when construction is tentatively set to begin. If Congress continues to reduce construction funding to keep commercial flights moving, grants like those that would fund the bulk of the runway rehabilitations could be threatened.
Bill Johnson, executive director of the Florida Airports Council, said there is a statewide concern that some projects won't get done. But he hasn't heard which projects are candidates for cuts. "It's too early in the game," he said.
Curry believes runways will still get top priority in coming years. "I don't see it having an effect on us in the near future. Our projects are such critical safety improvements they will not be directly impacted," he said. The cost of rehabilitation of the Collier runways could amount to 10 times the amount being spent on design and engineering.
If LaHood moves the maximum $253 million from the construction fund, it would amount to about a 10 percent cut in that area.
Curry is confident the local projects would go on even if similar cuts are made in 2014.
In fact, he's optimistic some construction money can still be acquired this year. Design and engineering work on both projects should be completed by June, he said. That would put Collier County in a position to receive discretionary money that may be available late in the fiscal year if projects in other places come in under budget.
Curry said he's focused on that possibility, rather than on future cuts beyond his control. "The only thing I can worry about is putting the airports in position as soon as possible so we can be eligible for that money. You would hate not to be eligible for 2013 discretionary money that you missed only because you weren't ready."
In the worst case, Curry says the FAA may only fund one of the two airports in 2014 and another in 2015. Or it could stretch what would be one-year projects over two years.
Even though the runways at Immokalee and Marco Island have been rated as "very poor" by the Florida Department of Transportation and even though the federal government is paying for the bulk of the work, the projects have not been without controversy.
In December, Collier County commissioners Georgia Hiller, Tim Nance and Tom Henning voted to stop the design. Only a warning from Curry, corroborated by Crystal Kinzel with the clerk of courts office, that the FAA would penalize the county for not proceeding with the effort to maintain safe runways moved them to reconsider.
If the FAA makes money available for actual construction next year, the county will have to apply for it and provide the local match, another possible hurdle, given the commission majority's tepid support for the work.
(Connect with Brent Batten at firstname.lastname@example.com)
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All Stories
Vote expected on Porterdale water
PORTERDALE - The first and second readings of an ordinance to increase water and sewer rates in the city were heard Monday night by the City Council.
Oxford passes rollback millage rate to maintain tax base
OXFORD - The city of Oxford passed a rollback millage rate during its monthly meeting Monday night.
Moo'ved for a free meal
Photo: Erin Evans
Newton Phone poll - 07/11/09
The Newton Citizen Poll is a compilation of opinions submitted by readers. They do not necessarily reflect the opinions of the Citizen newspapers. If you agree or disagree with something you read here, you may respond by e-mailing email@example.com. This week's poll was an open line.
Feline license plate available
COVINGTON - Feline Friend license plates are now available at tag offices throughout Georgia, according to a press release from the Humane Association of Georgia. The license plate depicts a black-and-white tuxedo cat, a design that was selected last fall in a statewide contest.
NCSO gets $155K for CSI units Radios to be bought as well
COVINGTON - The Newton County Sheriff's Office has received a $155,917 grant to purchase two crime scene investigation units and 30 portable radios.
New design for licenses announced
CONYERS - Georgia drivers will begin to see a new look to their driver's licenses later this year following an announcement Thursday by the Georgia Department of Driver Services of a major overhaul of the state-issued driver and identification cards.
Government Meetings - 07/11/09
Conyers drops 3-2 decision to Gainesville
GAINESVILLE - Once Gainesville began playing small ball, Conyers was in big trouble.
Woman assaulted, robbed in pharmacy parking lot
CONYERS - A Conyers woman was assaulted and robbed in the parking lot of the Walgreens pharmacy earlier this week after a woman asked her if she could use her cell phone.
Community Calendar - 07/11/09
July 11
Maddux's No. 31 to be retired
ATLANTA - For the second time in three months, a major league team is retiring Greg Maddux's number, leaving the Hall of Fame-caliber pitcher feeling humbled and a little confused.
Busch calls solid season 'pathetic' so far
JOLIET, Ill. - Kyle Busch is having the type of season most drivers would envy.
Francoeur traded Braves send right fielder to Mets for Church
Jeff Francoeur's storybook journey from Parkview High legend to Atlanta Braves' star and Sports Illustrated cover boy captivated metro Atlanta for years.
Armstrong drops to third in Tour
ARCALIS, Andorra - Lance Armstrong dropped one spot to third place in the Tour de France on Friday, with rival and teammate Alberto Contador breaking away in the final sprint up the mountain to claim second.
EMC meeting set for Thur. Snapping Shoals gathering planned at horse park
CONYERS - Snapping Shoals EMC will hold its 71st annual meeting on Thursday at the Georgia International Horse Park in Conyers.


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I always struggle with decorating my home, but love photos of my family and kids on display around my home. I have the usual 8x 10 and 5×7 photos on walls and in picture frames throughout the house.
A while ago, I walked into a friends home and fell in love. She had photos of her family and children at all stages of life in large poster-size prints hanging in frames on all her walls. It was really the only artwork on her walls and it was beautiful. There were gorgeous shots of her family posing, playful shots of her kids running, and even silly shots of her children making faces at the camera. For some reason, I'd never through to blow up my photos larger than 8×10, but I loved the feel it brought into the home.
UPrinting, an online printing company. offers a few different options for canvas printing and ways to display your family photos throughout your own home, along with printing for all your business needs.
One (1) lucky In Good Cents reader will win a FREE 16×20-inch Rolled Canvas ($14 value) with 2-inch border or no border and free 1-business day turnaround shipping.
How to Enter
Giveaways on In Good Cents are run via entry form. Comments do not count towards entry. You will receive one (1) additional entry for each completed bonus entry.
Required Entry Question
1. What photo would you love to display on a canvas? Tell me a little about it!
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1. Subscribe to In Good Cents via e-mail or RSS, AND confirm your subscription.
2. "Like" In Good Cents on Facebook.
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Entries will be accepted from now until 11:59 P.M. Eastern on Wednesday, September 28, 2011 and announced on or after Thursday, September 29, 2011 the giveaway page. Check out all the current giveaways for more chances to win and look at past winners!
Sponsored by UPrinting and conducted by In Good Cents. For more information, please read our terms & conditions and disclosure policy.


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Haley Peters scored 17 points and grabbed 20 rebounds in Thursday's win.
Peters, No. 2 Duke Dominate USC Upstate 123-40
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USC Upstate Postgame Press Conference: Duke 123, USC Upstate 40
Chloe Wells Postgame Interview: Duke 123, USC Upstate 40
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Joanne P. McCallie and Haley Peters Postgame Interview: Duke 123, USC Upstate 40
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– Duke got to face an overmatched opponent for the first time this season, and the second-ranked Blue Devils wasted no time taking advantage of the opportunity.
Tricia Liston
scored 20 points and
Haley Peters
had 17 points and a career-high 20 rebounds as Duke beat South Carolina-Upstate 123-40 on Thursday night.
Elizabeth Williams
had 17 points for Duke (2-0), while
Alexis Jones
Chelsea Gray
added 14 each and
Chloe Wells
had 10 in its home opener.
"I'm happy the team played hard throughout and was focused throughout the game," said Duke coach
Joanne P. McCallie
, whose team opened the season with a 70-58 victory at No. 9 California on Sunday. "There was a lot of energy off the bench.
"Our first group did a good job setting the tone. And I know there was a wide margin, but I thought we were very efficient. I thought we were smart with the basketball for the most part. We went after things and improved and all that was good."
Maddie Herr had 10 points to lead Upstate (2-2).
"Obviously it was a tough game for us," Upstate coach Tammy George said. "They were who we thought they were, No. 2 in the country and the score kind of indicates that. Playing last night (a 75-69 loss at High Point) was kind of tough.
"I think it's good for our program to come play teams like this and see what the bigger side is all about. It kind of lets you know where you are and what you need to work on. It lets you know what your weaknesses are. It's tough when all their kids are bigger, faster, stronger."
Eleven players scored for Duke, which committed 17 turnovers to the Spartans' 30. The Blue Devils had 22 steals, six each from starting guards Jones and Gray.
Liston, one of five seniors on the team along with Peters, Gray, Wells and
Richa Jackson
(six points) had nine rebounds with a career-best six assists.
"I've just worked on my overall game," said Liston, who was on the United States' gold-medal winning team at the World University Games in Kazan, Russia. "I think playing with U.S. Basketball over the summer really helped me play against good competition where (I) usually just practice. I'm trying to be versatile and aggressive, making plays happen and not waiting for things to happen for me."
Duke's scoring record is 128 points against Howard on Dec. 6, 2002, and the record for margin of victory is 89 in a 117-28 win over North Carolina Central on Dec. 28, 2009.
Duke shot 56.8 percent from the field while the Spartans' shot 20.7 percent. The Blue Devils finished with a 63-24 rebound advantage in their 123rd straight home victory against unranked opponents..
The Blue Devils led 60-18 at halftime behind 11 points from Williams and 10 from Gray. Duke, which had runs of 17 points and two of 16 in the half, shot 52.5 percent to the Spartans' 21.4 and had 33 rebounds to Upstate's 10.
Peters made it 100-27 on a layup with 9:06 to play.
"After the first game I wasn't happy with myself at all," Peters said. "I just wanted to be aggressive with the ball and focus better. For me there were a lot of little things that said `It's time to get going now.'"
Duke won the schools' only previous meeting, 93-35 on Dec. 11, 2011.
Last Chance - Sign Up for True Blue Golf Classic
Duke Celebrates NCAA Anniversary with Bracket
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Blue Devils Meet with Media After Practice
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Azurá Stevens Talks with the Media Thursday
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Cali's Finest is the premiere lifestyle brand that is taking the world by storm, bringing the best Cali has to offer by meshing the Southern and Northern California cultures. Cali's Finest fuses music culture and art with action sports and street wear to create one cohesive style – the ultimate lifestyle brand. Cali's Finest takes everything California represents and puts it into a clothing line, therefore making the Cali lifestyle a movement. From surfing to skateboarding, reggae to rap, and palm trees to bridges, Cali's Finest lives and breathes the culture of California. Enter for a chance to win their best-selling t-shirt, Northern Lights, and visit the website to purchase other Cali's Finest gear just in time for summer at www.CalisFinestClothing.com.
4 lucky winners will receive one Cali's Finest Northern Lights T-Shirt.
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Cast of Humse Hai Life Celebrates Christmas with IF
Added on 12/27/2011
By : tellybuzz
Overall Rating :
Rate Me... Rating Saved!
View : 55663 Comments : 17 Video Courtesy : www.india-forums.com
|Total Votes : 18
|chaithusnowdoll, cvhhl, 11122, abhiya1, �t_skit, anuja_me, nehnehneji, Yuvian_forever, Sunni.L.Arman, shiningstarz, Jotz_92, cuteangel...., mini_ksg_AR, vrushanharshi, -Yami-, prc_fan1, Roshini1494, pratsy
yuvi..u r sooo cutupie
love u
HHL rocks...
aww hhl rocks love you yuvi and whole caast
omgg yubi yayyy <3 thanks lot i-f for their interview yuvi abi rocksss and ya hhl too
tnks for the video ...hum se hai life rocks
Awww...Love YuBi...They both are so cute...<3<3<3...Thanks a lot for the video IF...
Aww... all 4 of them are so cute :)
and Gurmeet looks so different off-screen.
But where's Himansh?
Merry Christmas & Happy New year to all !
no himansh
abi looking cutie pie cutooo [8->]
Raaghav's Birthday Celebration on the ...
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On Safari at hooga
Posted: July 10, 2012|
Comments (0)
AN indie night par excellence is on offer at hooga on Tuesday, July 10 with four acts playing the Chelmsford venue.
Topping the bill are Hertfordshire synth-popsters Safari with great local support from singer songwriter David Harvey, garage rockers Mandeville and electro-rock supremos Sans Wilfred. Entry is free.


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Tennessee head coach Butch Jones along with quarterback Justin Worley and wide receiver Marquez North will preview the Utah State game on Tuesday at 12 Noon.WATCH LIVE AT 12 PM
Click here for the original story.
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What is the base of your irrigation system?
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The King Innovation Cable Saw is the perfect solution for cutting pipe in tight spaces. No more trying to wedge a saw in some awkward corner. The cable saw is easy to use and is constructed of a durable stainless steel cable and comfortable plastic hand grips. King Innovation cable saws work well on all types of PVC pipe, including plumbing, drain, and irrigation pipe.


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I was in Stuttgart, Germany in starting September for two nights, about 2,5 hour ride via ICE train from München. I find the city a bit different than the German cities (Berlin, München, Hamburg, etc): it was actually a calming city for me to see despite being the sixth largest city in Germany.
Sadly Stuttgart, Germany does not have a lot of vegan restaurants in the centre (one of them was a bit faraway which require a 30-minute train to get on), but surprisingly their groceries are packed with vegan products.
For breakfast, I would have Alpro Soya strawberry soymilk and organic fruit muesli with Provamel green lime yogurt. It definitely fills us up completely for the morning.
You can get these below products at the specific groceries, but hey it's worth a long walk, great for your legs and saves you shitload taxi fares:
1. Alnatura off Tübinger Straße 31, about 30 minutes walk from Mittlerer Schloßgarten.
2. Basic Bio off Breitscheidstraße 6, about 30 minutes walk from Mittlerer Schloßgarten.
For snack or midnight snack, I get addicted to these Wheaty sausages. It was a German brand and I like the fact that these don't have soy in it. The flavour was amazing, and I wish I can bring them back to the U.S. or anywhere I am. They have different kinds: Kür-Biss, Chorizo, Pyrossi, Red Hot Chili Peppers and Hanf (with hemp). My favourite ones are Hanf and Chorizo. All of them bombed with yummy flavours. I would get hundreds of them if possible. I think each Wheaty costs about €1,19, except for the fat one (70g / Red Chili Hot Peppers) about €1,89. I'm not sure, but I'm sure small ones are below €1,50 for sure at the German organic/bio stores.
You can get these varieties at Basic Bio off Breitscheidstraße 6, about 30 minutes walk from Mittlerer Schloßgarten. I can't believe I finally found my favourite German snacks!
For guilty snack or junk food , I really love REWE potato chips from Switzerland. There's something about these potatoes: fresh and unique. REWE is one of the most common groceries that you can find in Stuttgart, perhaps other German cities, too. They even make their own store brands and I really like their logo concept. It does stand out and all of their products are white. Click here to look for nearby REWE grocery locations in Stuttgart. Also at REWE, they have a small bread section for fresh pretzels (with ingredients in German), some of them can be vegan. Just watch out for dairy, butter or lard in German.
Some vegan products I've found at REWE:
For dessert , I know it is difficult without a main course in Stuttgart. But I had plenty of snacking from the groceries, which filled me up. I found an Italian vegan brand, "Valsoia" which I remembered having it in Roma, Italy. You cannot find that in Austria at all, which disappoints me because that was one good frozen ice cream cone ever.
1. Where I found it? At "Edeka." Address: Gaisburgstraße 2-4a, Stuttgart. I don't think you can find these products at REWE or the organic groceries in Stuttgart, only at Edeka unfortunately.


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If you are Earth conscious then you know that of all the office supplies business cards are the most used and often the most discarded, what a waste. Now, imagine a service that allows you to convey the same information contained on a business card, without the paper. CardWerkz offers such a service. Instead of paper business cards, have texted business cards. The service allows the same information contained on the business card, but it is delivered via text messaging, thus saving thousands of trees.
One of the main obstacles cited when discussing business cards is the old adage that they convey the professionalism of the business, but a text business card states that the business offering this form of communication is green conscious. The main goal of any business card texted or printed is to provide contact information, but to say that the business also cares about the environment says a lot more.
There are many advantages to having a green business card the biggest being saving the environment, but wouldn't you like at the end of a presentation to have a PowerPoint slide that say "To Get My Business Card Text (your company keyword) To (cardwerkz short code)." This allows you to spend more time talking about your product or service, and less time lugging around a stack of business cards making sure everyone gets one before they run out.
In the near future there will be a time when all forms of communications will be transmitted by electronic means, but this process has to start with the simplest of ideas, and that's the goal of the texted business card.
For more information on ways to save the environment, visit your favorite search engine and research going green. To start your business using an environmental friendly business card visit the CardWerkz website at http://www.cardwerkz.com
Thanks for all of the great information on green business cards. I believe that using Green recycled business cards can help out our environment tremendously. I have been using a website called ZimmZang for all of my Green Business cards. I believe that the go green contribution with business cards can help turn around and save billions of trees. Just a recommendation!


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- Northern New York Newspapers
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Republicans in the state Legislature flatly rejected the notion of passing one particular bill that would increase the minimum wage on Tuesday, but left plenty of wiggle room to eventually support a compromise.
Its not that Im totally against an increase in the minimum wage, said Assemblyman Kenneth D. Blankenbush, the Black River Republican who voted against the Assembly Democratic majoritys version of the hike. I just feel like a 17 percent increase, plus (automatic increases to) adjust it every year, is something that I couldnt support.
The measure passed the Democratic-dominated lower chamber on Tuesday but Republicans said it wouldnt pass in the Senate, which they control.
But it might not be the end of the road for some sort of minimum wage hike.
Senate Majority Leader Dean Skelos, R-Long Island, narrowly responded at a news conference that: Im just telling you, we will not pass the speakers bill.
That leaves a wide berth for compromise, which could change the terms of the current proposal, which is to increase the minimum wage from $7.25 an hour to $8.50 an hour. The minimum wage would rise yearly with the rate of inflation.
State Sen. Patricia A. Ritchie, R-Heuvelton, also left room for compromise while rejecting the bill passed on Tuesday by the Assembly.
Senator Ritchie does not support the bill passed by the Assembly, Graham Wise, her chief of staff, said in an email. She is concerned that this particular legislation will hinder, not help, job creation in her district.
In a follow-up message about whether she was leaving room to eventually support a minimum wage increase, Mr. Wise said: She has not seen any proposal that she can support.
Mr. Blankenbush held a roundtable discussion on the matter in Gouverneur. He said that mostly small businesses showed up, and that nobody supported an increase in the minimum wage. He suggested that the agriculture community, which is subject to the whims of a volatile market, should be exempted from the increase. The Republicans in the Senate and the Democrats in the Assembly could reach some sort of compromise that would get rid of the yearly increases, Mr. Blankenbush said. It might also involve tax breaks for small businesses, a proposal that Senate Republicans put forth earlier this year.
If a minimum wage bill is to be passed this year, it would have to be a different bill with compromises in that bill, he said.
Assemblywoman Addie J. Russell, D-Theresa, voted to approve the measure, though she conceded that it didnt really have a chance in the Senate. Striking a populist tone, Mrs. Russell said increasing the minimum wage could help stimulate the economy by putting more back in the pockets of working families.
We have gone down the corporate welfare road, and those types of policies just dont appear to be working, she said. We have very large employers who are just sitting on piles of cash and are not hiring.
She, too, was open to compromise, saying that the final bill may not include an annual increase in the minimum wage.
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
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JDO 2.0 approved
No formal votes against
In Projects and
Communities, the JSR community points to the recent vote to approve JSR 243 on JDO 2.0. There were twelve yes votes, four abstentions, and zero no votes. The comments that accompany the votes are illuminating. The JBoss comment made it clear that they were not supporting the spec and why, but they felt an abstention was a more appropriate vote. When we launch this week's poll tomorrow we'll ask you how you feel about this vote.
The NetBeans Community reports that their IDE is Developer.com's open source tool of the year. Developer.com lauds the IDE for its cross-platform support, J2SE 5.0 integration, extensibility, and flexibility.
JSR community leader Michael Nascimento Santos blogs The JCP EC (and the community) did the right thing: JDO 2.0 approved in today's
Weblogs . " After a long time of uncertainty, the JCP Executive Comitee has done the right thing by approving JSR-243, JDO 2.0. But the community deserves credit for that as well. "
Meanwhile we have two conference reports. Tom Marrs checks in with a look at JBoss World 2005 Conference - Day 1 and Scott Schram report on EclipseCon - Tim O'Reilly Keynote.
In Also
in Java Today , the Apple Developer Connection is running an article on Developing Java applications on Mac OS X with Eclipse. The article presents "three examples. The first, the classic HelloWorld example, introduces the IDE, shows you how to create a project, and how to create, compile, and run a class. For the second example, we will import the base Swing application created by Xcode and work with it in Eclipse. You will also learn how to customize the Eclipse environment and start taking advantage of the Java-specific, code-aware features such as code assist and refactoring. In the third example, we will work with an example that introduces the Standard Widget Toolkit (SWT). "
Swaminathan Radhakrishnan writes, "Session beans are used for business logic components and are primarily of two types: Stateful and Stateless. The type of the bean, stateful or stateless, is decided at deployment time through some deployment parameters." That's fine, of course, until a stateless bean picks up some data that it should start holding onto, meaning it needs to become a stateful bean... a runtime change that is generally not possible. In On-Demand Stateful EJBs, he proposes a design pattern for building a system to accommodate this scenario, allowing stateless session beans to become stateful on the fly.
What about
Weekly/nightly builds of JAXB 2.0? In today's href="http://forums.java.net/jive/index.jspa">Forums, Spiff requests "Is it possible to get nightly/weekly builds of JAXB 2.0 RI, or perhaps access to its CVS repository? I got an exception when I ran the release from a few weeks ago on my schema and I'd like to see if that has gone away in recent builds."
RLopes has been wondering about Integrating vector graphics into Swing and writes "I was thinking the same while i was trying to make a synth theme, it would be really nice to have an svgpainter (like imagepainter)".
In today's java.net
News Headlines
- JDO 2.0 JSR Passes Second Review Ballot
- Apache Axis 1.2 RC3
- Groovy Beta 10
- Spring Framework 1.1.5
- Apache Lenya 1.2.2 - CMS
- Ozibug 2.2 - Web Based Bug Tracking
- JX-Mail Initial Release
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text:
booking information
Click here to view our live online booking system for up-to-date availability, prices or to make a booking
Please ring Simon or Margaret on 01805 601623 if you have any questions or if you would prefer to make a booking by telephone
To send an email enquiry click here
Our prices are inclusive of heating, electricity, bed linen, towels and baby equipment
Prices are in pounds sterling and include VAT
Pets cannot be accommodated at Birchill Farm Cottages. There is a kennel/cattery a few minutes drive away: Fursdon Farm Kennels 0800 756 3190 www.boardingkennelsinbideford.co.uk
Parking spaces are limited to those stated in the individual cottage descriptions. Please contact us prior to booking if you need an additional space, as this may be possible
Visits by non resident family and friends are strictly by arrangement with us.
Seasonal events Christmas and New Year - Christmas trees and decorations are provided. A festive hamper is included in the price of bookings of seven nights or longer
Paying for your holiday A deposit of one third of the total tariff is payable when booking your holiday. This is non returnable. You are requested to pay the balance four weeks before the start date of your holiday. If you are booking your holiday less than 4 weeks in advance of your stay, the full amount is payable at the time of booking
Payment may be made by cheque (made payable to 'Birchill Farm Holiday Cottages'), bank transfer or debit/credit card (excluding American Express and Diners cards).
Arrival and Departure Your cottage will be available from 4pm on your day of arrival. Please let us know what time you plan to arrive after 4pm.
Your cottage must be vacated by 10am on your the day of your departure.
Late arrivals (after 9pm) are by prior arrangement only.
No Smoking For the comfort of all our guests, you are requested not to smoke in any of the cottages.
Please click here to read our Terms and Conditions


text:
Vietnam's no-frills carrier Jetstar Pacific will begin a daily flight between Ho Chi Minh City and Bangkok on Dec 10.
The move marks a further international network expansion of the airline which until recently focused on the domestic market in direct competition with arch rival VietJet Air.
Jetstar Pacific's announcement of the service came shortly after the privately owned VietJet Air said it would boost the frequencies on the Bangkok-Ho Chi Minh City route to twice a day starting on Sept 12. This will double VietJet Air's capacity to over 5,000 seats a week and is said to be in response to stronger demand.
Jetstar Pacific, which operates as part of the low-cost carrier Jetstar Group linked with Australia's Qantas, will use the single-aisle Airbus 320, similar to that deployed by VietJet Air, for the new service.
The flight will depart from Ho Chi Minh City at 1.05pm and arrive in Bangkok at 2.35pm. The return flight will leave at 3.20pm from Bangkok, arriving in Ho Chi Minh City at 4.50pm.
The Ho Chi Minh City-based airline currently serves Hanoi, Danang, Vinh, Haiphong, Buon Ma Thuot, Nha Trang, Phu Quoc and Hue.
Bangkok will be Jetstar Pacific's second international destination after Macau.


text: If you own a D70 you simply can't be without this item. Because Nikon chose not to include a mechanical cable release option (or an electronic one either), it is difficult to shoot at slow shutter speeds, even on a tripod, without getting camera shake affecting your images. You can use the timer, but that doesn't always work for your shooting situation. With this remote, you get the same basic operation as a cable release as well as a bonus that you can put yourself in front of the lens and use the remote to trip the shutter release. It also works in combination with the self timer. One small concern is that because it's an IR remote, you must point it at the sensor, which is on the front of the camera. This can be awkward standing behind a tripod, but not seriously. I really enjoy using this product.


text:
On this page you will find important information about Sewing Shanty based in Richfield, PA, like the address, contact person and details, as well as the email address and home page.
Sewing Shanty
Fabric Shop
For travel by car, directions from your location to Sewing Shanty at 14410 Route 35 in Richfield, PA will be displayed via link >>my route<< below the map.
Sewing Shanty, the Fabric Shop in 14410 Route 35, the Richfield, the Pennsylvania 17086.
Mailing send it to the following address of Sewing Shanty:
For questions regarding Sewing Shanty you can call the following numbers, or find the appropriate contact on the homepage of Sewing Shanty.
To request more information about Sewing Shanty from abroad please call the international phone number +1.717.694.9141 under which you will be able to speak with the appropriate contact person.
Please send written inquiries and notices to Sewing Shanty from abroad to the international fax number or to the company email address. Call displayed telephone number to ask for respective email address of Sewing Shanty.
Here are some other interesting Fabric Shops from Richfield, the County Juniata and the U.S. State Pennsylvania are listed:


text:
By RICHARD SHAWStaff reporter
Last Thursday evening, I spent some time going through old editions of the Sun Advocate from the early 1930s looking for information about roads and highways in the area.
As I perused the microfiche, I found something I had forgotten about: the vote in 1933 to repeal the 18th Amendment to the United States Constitution or simply to repeal the prohibition of alcohol manufacturing, transport and consumption in the nation
According to the Sun Advocate at the time, Carbon County had overwhelmingly approved the repeal. And nationally, more than 73 percent of the voters had cast ballots for a "wet" country instead of a "dry" nation.
I had read about the repeal of prohibition years ago in history books, but had never actually seen newspaper accounts of the events at the time.
The next morning as I walked out of a local convenience store, two delivery drivers were pulling a pallet of beer into the establishment with a pallet jack.
"Super Bowl beer?" I asked as I held the door open for them.
The delivery drivers nodded in response.
As I walked back to my office, I had to think about how different things are today from what they were in the early '30s
If Americans wanted a drink back then, they would either have to make the beverage (prohibition allowed private citizens to make a very small amount of wine or beer for their own consumption) or go to an illegal source supplying alcohol.
After I went into the office, I sat down at my desk and noticed an article in the Salt Lake Tribune from earlier in the week staring at me from the papers piled on my desk. It concerned Utah anti-alcohol activists who indicate that they are going to "monitor" consumption and use at the Olympic celebrations.
It's funny how some subjects a person is exposed to seem to all weave together within the span of a few hours.
Only a few days before, I had seen on television how many foreign countries have set up "diplomatic houses" where they can serve liquor during the games. They bring the liquor in as part of the "diplomatic pouch" protection afforded to all countries under international law.
Although I haven't read or heard anything from the anti-alcohol groups about the situation, I am sure they are not happy.
In the years before prohibition, regulation of liquor was left to individual states. By the time Congress enacted the Volstead Act, more than half the states in the union were already dry and many others had strong controls governing liquor sales.
This had come about in reaction to the growing problem of alcohol abuse in the nation. However, it was also due to tensions between urban and rural areas.
In the early part of the 20th century, people from the country flocked to the cities to take better jobs in industry. Those who remained in the country saw this as a slap in the face and perceived city life to be overly materialistic and sinful. In addition, urban growth had put a great deal of pressure on rural economies. Political issues started to divide along the country/city boundaries and none were as clear cut as prohibition. In fact, historian Andrew Sinclair once declared that prohibition marked the triumph of the "corn belt over the conveyor belt."
Prohibition started Jan. 20, 1920, one year after the 18th Amendment was ratified, giving businesses and manufacturers dealing in alcoholic beverages time to sell wares and comply with the law. It also gave criminals time to set up a network to distribute and supply liquor unlawfully.
I can imagine how busy every bar and liquor store were the week before the ban. It would have been interesting to see.
Prohibition may have been brought about by a rift in the country, but it was carried to fruition by radicals who wanted people to live the way they thought they should live.
Had prohibition succeeded, it is not beyond comprehension that tobacco would have also been eventually banned. Pornography would have included any art form portraying the human body without clothes. Music could only be produced under certain parameters of community standards and most of us would probably not know how to dance because it would be illegal.
But prohibition didn't work. In only a few years, polls showed that most Americans wanted the 18th Amendment repealed.
U.S. citizens recognized the hypocrisy and saw the crime created by the ban. Often, the individuals responsible for enforcing the law would go to a speakeasy to relax after breaking up stills with sledge hammers and arresting bootleggers.
The "Noble Experiment" is said to have failed. But prohibition didn't fail - it proved something. Governments cannot legislate and enforce laws that affect the basic human right of choice. People will make choices regardless of what a government maintains or what type of enforcement actions police take.
To see this with clear eyes, all we have to do is look around us. People speed in cars every day. Drivers get tickets, accidents occur and people even get killed. But it doesn't stop motorists from speeding.
The communist government of the Soviet Union collapsed for the same reason. The people under its rule became disenchanted with a government that tried to control every aspect of their lives. The more the rulers tried to control the population, the more the people's will dripped off the hard clenched fists that couldn't hold onto the power.
Today, we have people who would like to bring prohibition back. But this time, they are much smarter.
First, very few are using moral grounds to justify the cause, yet that is what is in the back of many of their minds. Today, they are using scientific data and causation of social ills as the rallying cry.
Organizations like the Utah Alcohol Policy Coalition claim they are only trying to keep our state safe and sane. But one can tell by the rhetoric they spew that keeping kids from drinking and making sure the state's liquor laws are not violated are only two small goals in the back of their minds.
Eventually, the organizations want alcohol totally banned. They want breweries out of business and liquor stores closed. They want no one to drink anything stronger than a Pepsi in the state and, ultimately, in the entire country.
No one can deny that many social ills and health problems are at least, in part, caused by alcohol. According to most highway safety and law enforcement experts, alcohol is involved in at least 50 percent of all fatal car accidents. But the disarming "we are doing this to protect society and young people" ploy does not play to well when people realize the freedom of choice that could be lost if one group gets its way and others jump on the band wagon. The operative word here is "radical."
When I first heard about Mothers Against Drunk Driving, I was all for the organization. People shouldn't drink and drive. If you look on the group's official website, you will find that MADD indicates that the group's reason for existence is to stop drunk drivers.
But the problem is that similar organizations frequently fill up with radicals. When MADD representatives speak on television, they often make little distinction between drunk driving and drinking at all. It is comparable to the negative comments many anti-gun activists make about gun owners. Incidentally, MADD has a side chapter promoting bills on gun control.
It is time that citizens realize how the radical elements in often benign sounding organizations can take the power of the group and turn it to personal purposes.
Attacking legal products, manufacturers and distributors as well as criticizing companies legally advertising products are typical ploys used by activitist. And when the legal maneuvers and antics affect the vote of one of our legislators, we lose some of our individual rights.
Citizens voted in 1933 to repeal the Volstead Act. Let's not allow the fear that radicalism preaches to turn back the clock to from the 21st century to 1920.


text:
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« Kibdelomycin, A New Antibiotic. In A Way. |
| Why Isn't There an ArXiv For Chemistry? »
Posted by Derek
When does China take the next step in drug research? They already have a huge contract research industry, and they have branches of many of the major pharma companies. But when does a Chinese startup, doing its own research with its own people in China, develop its own international-level drug pipeline? (We'll leave aside the problem that not even all the traditional drug companies seem to be able to do that these days). It still seems clear that we're eventually going to have a Chinese Merck, or a Chinese Novartis or what have you - a company to join North America, Western Europe, and Japan in the big leagues. The Chinese government, especially, would seem to find this idea very appealing.
Opinions differ, to put it mildly, about how far away this prospect is. But Chemical and Engineering News is out with an article on homegrown Chinese research that explores just this sort of question. But you run into passages like this:
In a meeting room in a building resembling a residential home in Shanghai's Zhangjiang Hi-Tech Park, Li Chen and John Choi describe the business plan of their new company. Called Hua Medicine, the firm will launch breakthrough drugs within four years, they predict. Hua will manufacture the compounds and sell them with its own sales force. It will also license its internally developed drugs to multinational companies.
Yet right now, Hua is a modest operation that employs eight people. Hua doesn't have an R&D lab yet, let alone a manufacturing facility. It operates in a loaned building formerly used by the administrators of the industrial park...
It can be easy to dismiss such ambitious business plans as simply talk aimed at gullible investors or government officials handing out subsidies. Except several start-ups are led by people who have long track records of success. Moreover, the money financing these start-ups comes not from relatives and friends, but from savvy investors knowledgeable about the drug industry.
Well. . .yeah. Let me join those who dismiss business plans that are as ambitious as that one. The way I understand the drug industry, if you're planning on launching a breakthrough drug within four years, you must have that drug in your hand right now, and it has to have had a lot of preclinical work done on it already (and in most therapeutic areas, it needs to have already hit the clinic). And note, these guys aren't talking about their one pet compound, they're talking about launching drugs, plural. Drugs that they discover, develop, manufacture and sell. And they have 8 people and no labs.
No, something is off here. I get the same feeling from this that I get from a lot of leapfrog-the-world plans, the feeling that something just isn't quite right and that the world doesn't allow itself to be hopped over on such a deliberate schedule. Thoughts?
Comments (47)
+ TrackBacks (0) | Category: Business and Markets | Drug Development | Drug Industry History
1. Virgil on August 29, 2011 12:07 PM writes...
Well, the article leads off with a picture of someone in a lab coat holding up a flask of colored liquid, so they must be serious, right? And with Alan Baxter from GSK on board, what can possibly go wrong?
2. Coere on August 29, 2011 12:19 PM writes...
You assume these drugs will be sold largely outside China. They will likely sell them within China for domestic consumption.
The business model is to test the drug on the consumer before actual trials begin.
Since the Chinese govt allows their population to eat and breath toxic waste, I can't see how this would be much of a departure from their current policies.
3. Student on August 29, 2011 12:24 PM writes...
Hypothetically...if they tested this stuff on their own people with extremely mild regulation, would develop nations still use that data for the approval process. If not, how hard would it be for them to bypass Chinese regulations as a homeopathic drug, maybe label it "modified herbal medicine" sell it, make lots of money, and then scale up to international regulations and become a competitor?
4. johnnyboy on August 29, 2011 12:33 PM writes...
@3: "if they tested this stuff on their own people with extremely mild regulation, would develop nations still use that data for the approval process."
"how hard would it be for them to bypass Chinese regulations as a homeopathic drug, maybe label it "modified herbal medicine" sell it, make lots of money, and then scale up to international regulations and become a competitor?"
If their compound is labeled a drug, it is not possible to follow the path you describe, they'd have to jump through the same regulatory hoops as every other drug, regardless of how big the company is. If their compound is labeled a herbal or nutritional supplement, then yes - hell they don't have to 'scale up', they could do it today as there is no regulation on those.
5. GreedyCynicalSelfInterested on August 29, 2011 12:40 PM writes...
Sounds like a stock promotion to me. They are promoting their stock to the unwashed masses, pump up the value, cash out and then disappear.
It does not have to be illegal. Does anyone remember "Planet Hollywood?"
6. johnnyboy on August 29, 2011 12:43 PM writes...
Is the example you cite from that article the best one they had ? If so, this reminds me of the "Biopunk" book you mentioned a while back. I bought the book and read through about half before throwing it across the room in disgust. Everything I saw in there was perspective-free, breathless hype about 'research' that's about 50 years away from yielding anything resembling a drug or a therapeutic approach, yet gets hailed by reporters unencumbered by perspective as 'starting a new biotech industry'.
7. Chemjobber on August 29, 2011 12:53 PM writes...
Here's my problem with that article:
Who was kidding who? Did Tremblay write this up, knowing that they were making fools of themselves... or is he really that credulous?
Or am I just a Luddite skeptic?
8. newnickname on August 29, 2011 1:10 PM writes...
I was at a biotech with a very ambitious business plan being promoted at all of the top VC road shows. It included powerpoints promising delivery of the first IND application in a very short, highly aggressive time frame. At first, I thought it was a typo with the wrong year (current year instead of current +1 or +2). That did not go over well with the MBAs.
Considering where we were (further behind than the Chinese guys mentioned by Derek above), I offered the opinion that the only way we would have an IND in that time frame would be if we took the entire remainder of our start-up money and bought one. The MBAs who came up with the business plan gave me looks that could have killed.
For those of you interested in the rest of the story, there was never an IND. There was never even a candidate for an IND. Most of the money went to lawyers, consultants and MBA-only "business dinners" at 4 and 5 star restaurants. Apparently, that's a part of MBA due diligence: seeing who can order the finest bottle of wine (which comes from fermentation, a biotech related process, which is about all the MBAs know about biotech and drug discovery).
I know this is Derek's blog and not a "forum" but I also wanted to mention the "Do We Spend Too Much on Education?" debate at the New York Times, Opinion Pages, "Room for Debate", August 23, 2011.
9. You're Pfizered on August 29, 2011 1:56 PM writes...
Education: French, English, Chinese, and Japanese speaker. MBA, University of Western Ontario, 1994. B.A. in Economics, Concordia University (Montreal), 1987.
With this background, maybe it sounded reasonable.
I think that there will be a lot of slick people with great PowerPoint slide decks who enrich themselves during this money grab, but very few will ever deliver on what they are promising, much like newnickname mentioned.
If it were as easy as this article paints it to be, pharma wouldn't be in the position it's in right now.
10. Gunter Leiderhosen on August 29, 2011 2:03 PM writes...
I wonder if there will be lead in these Chinese drugs...
11. Josh on August 29, 2011 2:26 PM writes...
I'd love to invest, but unfortunately I already sent all my money to this nice Nigerian man who sent me an email. He promised me $22,500,000 in return.
12. pete on August 29, 2011 2:41 PM writes...
The name of the company is Hua Medicine. That can be alternately pronounced as,
"Wha? Medicine?"
"HOO-AHH!! Medicine!!"
13. iridium on August 29, 2011 2:48 PM writes...
A drug in 4 years...
What about to try homeopaty?
It works very well a lot of people and since it is just water you could save a lot of money going in one step from
1. Thinking a cool name for the "drug"
2. printing the lable and being ready to sell it
that should work even in just 1-2 years....
14. quintus on August 29, 2011 3:00 PM writes...
All they need to do is employ 5,000,000 people to do the work and test the compounds on themselves (employees) and pay them peanuts.
15. Innovorich on August 29, 2011 3:21 PM writes...
I just stopped reading that paragraph at "breakthrough drugs within 4 years . . "
Like you say Derek, hopping the world does not happen. They might be catching up, but they're not already 3-4 times better and also able to circumvent regulation and many of the time consuming operations required just to make a clinically effective, manufactured and accepted drug.
Somebody is lying to get money for their life science company . . . this doesn't just happen in China!
16. Anonymous on August 29, 2011 3:33 PM writes...
I was interested and read the article Derek linked. Most of the start-up companies mentioned therein have the expressed plan of marketing to China only, which means that they aren't planning to do US clinical trials. However, there are a few companies mentioned that have, or are working towards, US clinical trials...don't dismiss the whole group just because Hua Medicine clearly has no concept of reality.
17. PharmaBoy on August 29, 2011 3:44 PM writes...
I assumed (although perhaps incorrectly) that the business plan was to secure the Chinese rights to an existing drug and "launch" it China. There are many drugs in the world and very few of them in China. To get an already approved drug on the Chinese market would take 3-4 years presuming the need for dose range finding and Ph III studies in the target population.
18. Stephen Fye on August 29, 2011 3:51 PM writes...
This type of 'optimism' and gullibility is not unique to China. I often review grants and/or have conversations with potential collaborators that overlook the need to 1) discover the drug (especially the chemistry bit is missed - drugs come from HTS right?); 2) develop the drug. Even in big US Pharma, every merger/reorg is followed by an announcement that the new management team has fixed the pipeline and now has great Phase III assets almost ready to launch (which came from the previous 'failed' paradigm(?)).
Immaculate conception is a great myth, reality is hard labor. You'd think the reporter's job would be to intervene with some industry averages for comparison.
19. HFM on August 29, 2011 3:51 PM writes...
@newnickname: I was at a biotech like that once. The MBAs asked the grunts to put together a flowchart depicting our estimated time-to-launch, which we did. I heard through the grapevine that they'd used our chart in a VC meeting...except on the X-axis, they changed "years" to "months".
Yes, that biotech no longer exists. And the beatings shall continue until R&D improves...
20. Chemjobber on August 29, 2011 4:03 PM writes...
Quintus! Long time, no see. How are you doing?
21. old man on August 29, 2011 5:30 PM writes...
If it sounds too good to be true...
22. Susurrus on August 29, 2011 6:46 PM writes...
Where the hell is Terry? I was expecting a lively debate about this one.
23. anonymous on August 29, 2011 6:47 PM writes...
This kind of over sell doesn't surprise me. Such is the solidity of CEO Wu's company that rumour has it that it hasn't been paying its workers.
24. Quintus on August 29, 2011 7:09 PM writes...
Hi Chemjobber,
I'm ok and you?
25. Quintus on August 29, 2011 7:12 PM writes...
26. Anonymous on August 29, 2011 8:11 PM writes...
yes, early days for them. However, they started the same with everything else. Nobody took them seriously. It may have taken 10 years to develop a drug for a company. But it only took 3 times that to develop the whole Chinese economy. Given time, they can make it happen. Btw, many people, including people who grew up and received their educations here are moving there. Do not just ridicule them.
27. Orion on August 29, 2011 9:36 PM writes...
I do not miss canceling my subscription to C&EN. Good journalism can be found elsewhere, in which I will enjoy reading how such fantastic claims play out.
I will agree with the general observation that the Chinese are not the least bit unique in their ability to spin such tales. They've learned from the best! I hope they learn from our mistakes as well.
28. Chemjobber on August 29, 2011 10:13 PM writes...
Good, quintus, things are fine. Hope all is well.
29. Sisyphus on August 29, 2011 10:44 PM writes...
"Drugs that they discover, develop, manufacture and sell." should read:
Drugs that they "acquired" the IP for, manufacture and sell.
30. Shazz on August 29, 2011 10:45 PM writes...
The unstated assumption is that the Chinese equivalent of the drug industry that could emerge in the coming decades will be an imitation of the (now failed) business model of modern western drug companies.
It ignores the possibility of the Chinese to do drug discovery in the way it was done before the 1970s (lots of animal models, lots of boots on the ground).
It also ignores the other possibility of the Chinese running with the emerging biotech tools in an environment relatively unencumbered by legislation and ethics. If a country is going to do wonderful/terrible things with genetic modification it will be China.
31. Sisyphus on August 29, 2011 10:49 PM writes...
"Do We Spend Too Much on Education?"
32. Moiety on August 30, 2011 2:26 AM writes...
Hype, hype and more hype. With nothing we will promise you everything.
33. JF Tremblay on August 30, 2011 3:18 AM writes...
Hi Derek,
I didn't know you had mentioned my article here. I came to In the Pipeline because I was looking for inspiration for an upcoming article on contract research.
The part of my article that is quoted on this website is the first few paragraphs. At that stage of a story, I don't want to burden the reader with a lot of details. John Choi of Hua told me that their first compound is still under development in the US where it has reached the NDA stage. That's what Hua wants to launch in China within 4 years. China will become the world's second drug market this year and growth continues. Comment No. 17 above is spot on.
One person above wrote that I am gullible. I don't mind that observation at all. I never know what to believe when China is involved, so I may be actually more gullible than 10 years ago. A lot of organizations have achieved a lot in a short time in that country, and others have promised things that didn't happen. I was introduced to the BioBay high-tech park in Suzhou when it was a PowerPoint presentation, and things there have developed as promised 5 years ago, more or less.
Separately, I welcome all suggestions about researching and writing an article about contract research, preferably one that involves Chinese companies because I am based in Hong Kong. Every October, C&EN publishes an article or a series of articles on contract research and I'm not too sure what to do this year. Many thanks. JF
34. A Nonny Mouse on August 30, 2011 6:34 AM writes...
Yes, I know someone (UK resident) who has set up a business in China (with government investment) which is involved in conducting clinical trials. Their objective is to take drugs that have not been licensed in China (or are at late stage 3) and to conduct the necessary trials for use in China. They then take a share of the revenues from the originator. I am told that they are working a couple of large US pharma companies (names withheld just in case).
35. emjeff on August 30, 2011 7:12 AM writes...
I'd love a look at the lab notebooks, wouldn't you?
The whole article is a bunch of breathless hype, written by some journalist who could not pass "Kiddie Chem", and who has absolutely no concept of how research is done. My respect for journalism is at an all-time low.
36. Anonymous on August 30, 2011 8:22 AM writes...
Hi everyone
As I promised I returned to china, now I am working as a production manager in a fluorochemical company to help to design their product line, R&D. As I wrote here before, to find a chemical job in china is not as difficult as in US. I am proud to work for a Chinese company and develop the frontier chemicals to replace the china market of 3M and DuPont and compete with them on international market.
Since Derek is discussing the competition of drug discovery in china, I'd like to give some comments. It seems everyone here doesn't know the model in China of development of new drugs. As to my knowledge I can describe two drugs development strategy.
The first strategy is formal model, me-too strategy, usually FDA doesn't encourage me-too drugs in US, that's why in these days multi-international companies don't want to spend too much time to develop me-too drugs. However, in china, the government found it is more realistic to encourage me-too drugs development rather than develop new chemical entry, at least it also has its own intellectual property.
Thus a Chinese company can synthesize 50-200 similar chemicals of approved drug in US as drug candidate and further test the bioactivity and for clinical trials. It does takes about ten years to market a me-too drug. One example is "Imrecoxib"
Another strategy is bio-drug, usually there are 200 failed bio-drugs in US which reach phase II or Phase III. And there is no IP in china due to the unpromising future, thus some companies found that modifying the candidate and try the clinical trial in china can be promising.
One example is "Endostar"
After these introduction I hope you can understand these two models, if you want to do business related with chemicals, especially bulk chemicals, you can find my company for collaboration(we have a lab with 50 master level employee and a factory with 1000 ton capacity for relative simple chemicals). In addition, if you are doing drug discovery in china I may give you some suggestion as a paid consultant, probably I am one of the best professionals in drug industry in china. Good luck to you guys.
Regard hua company I can assure you guys that they don't have IP either in US or in china, 4 years for a new drug is impossible in china, usually even a generic drug need two years time to approve.
37. LFV on August 30, 2011 8:36 AM writes...
The claims made by the Chinese pharma group just sounds like an updated version of The Great Leap Forward....and I'm expecting similar results from this trial.
38. RB Woodweird on August 30, 2011 8:51 AM writes...
Well, if 10,000 Pfizer employees take 20 years to get a drug to market, then 50,000 Hua Med employees can get one to market in 4 years. Do the math, people.
39. MoMo on August 30, 2011 10:26 AM writes...
C and E news and the ACS should just change its name to the Asian Chemical Society.
Thats all I have been reading about in this rag is about how great things are going in China and how dismal we are at research these days.
More treason and more reason to stop ACS membership all together and start publishing in PlOS or other online journals. Your days are numbered ACS, so milk it while you can!
And when it comes to taking a drug from China I hope the editors at the ACS like Baum are the first in line.
40. anonymous on August 30, 2011 1:26 PM writes...
To the FDA, an NME is an NME. FDA doesn't give jack about whether it's a "me-too drug"; . It's the payors that want added-value for the added cost (theoretically). If its not an NME, then there is the 505(b)(2) pathway, which requires a lot less testing than a full NME (b)(1).
This gets to the second part: you still have to have the IP space to operate for a b2. What you are suggesting is that China is flagrantly and blatantly ripping off IP holders everywhere else.
I'm stunned
41. Dr Manhattan on August 30, 2011 2:00 PM writes...
Stunningly unsophisticated, and indicates that they have a long way to go in just learning the business. I had several Chinese scientists com over to our lab in the mid-1980's. The Cultural revelotion gutted an entire generation of science, and tehy still have some way to rcover. Remember, the much vaunted Chinese manned space program is currently having a redux of NASA'a 1960's Project Gemini.
Soon though, you will be able to buy compounds similar to some Western drugs...but now with melamine!
42. @China on August 30, 2011 3:27 PM writes...
Rampant corruption and a peculiar sort of innate gullibility when it comes to home grown or state projects is rampant in china.
Currently both the west and the 'east' aren't spending enough on the 'right' sort of education. Bottom line, it's always about passion combined with innate field specific intuitive expertise at the top when you're talking about any hierarchical organization that's going to make 'something' - money is a byproduct of this (generally a massive one) but when it's the goal it's mediocrity or will devolve into such. These people exist, they're just enjoying their work and lives too much too do attempt such logistical everest like distractions most of the time.
How do you think you'd do at the top Derek?
I'd invest.
43. Healthy on August 30, 2011 5:55 PM writes...
I agree that it seems that just because of the clinical trials their intentions seem ahead of schedule. Anyway, I think that these leapfrog-the-world are a good thing as they force quantum leaps instead of slow overdoing. The former is a way more unsecure bussines but when it successes it is really more meaningful. Moreover, if you take a look at chinese brands they reduce the final product cost by reducing intermediaries insurmoantable commisions which are basically drugs fault.
For research lines, ideas, peers and funding please check the non-profit agingportfolio.
44. Coughing on August 30, 2011 7:10 PM writes...
What about aquisition..... If they have the money.
45. WB on August 30, 2011 11:47 PM writes...
I wouldn't be surprised if all they can come up with is some traditional 'Chinese medicine' that would never get FDA approval. And they are very likely to get their government's approval to sell placebos and snakeoil. It's going to be another complementary medicine sham.
46. Guppy on August 31, 2011 12:27 AM writes...
I can kind of see how some of these mee-toos might be useful for Antibiotics.
In nature, these sort of compounds often aren't produced as a single pure entity, but as a cluster of related entities with little tweaks in them. Having a variety of each might slow down how quickly their targets get their resistance mechanisms optimized.
47. George Baeder on September 16, 2011 2:03 PM writes...
I stumbled across this forum by accident. The level of provincial ignorance in these comments is amazing. Apparently someone saw a paragraph somewhere and is drawing conclusions without any understanding of Hua's strategy (license in compounds at Phase II) This sort of willful ignorance is identical to attitudes I saw in:
Textiles in the 70s
Consumer electroncis in the 80s
Telecom in the 90s
Does anyoone actually think that Pfizer or Novartis represent the "model" for the future of the industry? And that success in China means creating a home grown dinasour on Western platform? Think again. A new model is beginning to take shape.
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