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"Antioxidants Accelerate Lung Cancer Progression in Mice"
Sayin, and colleagues suggest in a January 2014 paper published in Science Translational Medicine that mutant mice, which are genetically modified to be susceptible lung cancer and undergo tumor initiation through inhalation of a genetically modified virus, have worse outcomes when given a synthetic vitamin E analog or N-acetylcysteine. It is unclear how this study relates to antioxidant intake in normal mice, let alone the human experience. This data is inconsistent with research demonstrating antioxidant supplementation reduces cancer risk in humans. For example, a major study (Physician's Health Study II) reported in 2012 that daily supplementation with a multivitamin containing a variety of antioxidants significantly reduced cancer risk. 1
However, the media is releasing shocking headlines related to antioxidants and cancer based on this one mutant mouse study. There are several problems with extrapolating the data from this article to the human experience. Also, a substantial body of evidence demonstrates antioxidants are cancer preventive.11-32
Mutant Mice
The mice used in this study were genetically modified to be susceptible to lung tumors. Also, the mice were given a genetically modified virus via inhalation to initiate lung tumorigenesis. Considerable differences in human and mouse physiology means that research on genetically modified mice may not reflect outcomes in humans.35
Synthetic Vitamin E Used
A synthetic vitamin E analog was used rather than the more biologically active natural vitamin E. This synthetic form of vitamin E is not equivalent in chemical structure or biological activity to natural vitamin E.2 The pharmacology of synthetic vitamin E is quite different from that of natural vitamin E; it demonstrates an entirely different dose-response curve, and is an entirely different drug by modern pharmacological standards.3
Also, only the alpha form was used; it is clear from the developing research that a variety of tocopherols, including gamma, should be used in dietary supplementation for optimal results. Using a single tocopherol form, such as this synthetic vitamin E analog, has the potential to reduce other important tocopherol forms that may inhibit tumorigenesis such as gamma tocopherol.4-6
Doses not reflective of typical supplement use
The high-end concentration of synthetic vitamin E used in the in vitro model was supraphysiologic at 100 µM; compare to normal vitamin E plasma concentrations in the range 8-28 µM. Using 20 µM as an typical vitamin E concentration in plasma,7 this means that the in vitro portion of the study used a concentration 5 times higher.
Also, the mutant mouse portion of the study used a very crude and imprecise method of dosing the animals via water and food supply. The level of NAC in drinking water was 1 gram/liter. Since an adult mouse weighs on average about 25 grams, and since the average mouse ingests about 20 ml of water daily, and further correcting for interspecies differences in body surface area and differences in bodyweight between an average mouse and an average 80 kg human, this yields a rough estimate for a human equivalent dose of more than 5.2 grams of NAC. This dose of NAC is much higher than a typical dose of NAC used as a dietary supplement,more than quintuple, in fact.
Results do not apply to a healthy population
The failure of the mainstream media to thoroughly explain Sayin's research will undoubtedly cause many healthy individuals who use vitamin E and N-acetylcysteine to worry that they might be increasing their lung cancer risk by doing so. This is absolutely not what was examined in this research.
The scientists looked at what would happen when mutant mice with artificially-induced lung cancer were given synthetic vitamin E and N-acetylcysteine. No aspect of the animal experiment provides any evidence that these nutrients cause cancer under normal conditions. Similarly, the work on cell culture in this study also does not suggest that vitamin E or N-acetylcysteine initiate lung cancer under normal conditions.
Preclinical research with very limited relevance to humans
Cancer occurs when genes that control cellular growth and death cycles become mutated or dysfunctional.36 A number of specific genes are known to be important drivers in specific types of cancer if they become mutated. These are called proto-oncogenes. Once a cell acquires (or inherits) a mutation in a proto-oncogene,irregular cell growth may occur.37However, this does not necessarily mean that a single genetic mutation will cause overt cancer. Typically, a driver mutation in a proto-oncogene initiates a cascade of cellular dysfunction causing mutations in numerous other genes involved in cell growth. Eventually, this leads to cancer. In some cancers this takes decades, whereas in others, such as aggressive cancers of the blood,cancer can erupt within weeks.38
The researchers utilized mice developed to harbor specific mutations that can be "activated" upon exposure to a specialized viral inducer.Once the mice harboring these mutations are exposed to the viral tumor inducer,they develop lung cancer soon after. This model diverges considerably with the development of lung cancer among humans, which typically takes decades of chemical insult. Although animal models are tools essential for the advancement of science, they only offer small clues about variables that might be relevant to human diseases. Animal models allow researchers to develop hypotheses, which then need to be tested in humans. Very often, an effect consistently observed in an animal model fails to translate to human beings.39
The mass media tends to over-emphasize and misconstrue this type of preclinical research, resulting is misinformation spreading like wildfire among the public. Animal models are interesting, but conclusions about interventions in humans must be based upon research conducted in humans.
Results do not apply to other forms of antioxidants
Different antioxidant ingredients have different biologic effects and it cannot be assumed that all antioxidants will have the same effects.40 For example, if we were to believe the outrageous media headlines about antioxidants and cancer, we would avoid antioxidant-rich vegetables and berries due to concerns about cancer risk. This is obviously preposterous and illustrates the risk of extrapolating this data to other antioxidants and tohuman populations.
Results are inconsistent with previous research
Previous studies show that antioxidants are protective against chemically induced lung cancer.8-10For example, NAC prevented the induction of lung tumors when supplemented to the diet of mice both before and after injection of a carcinogen. The researchers also noted that their results "…rule out that NAC may behave as a tumor promoter…"8 Previous research also demonstrates that NAC has an impressive array of mechanisms and protective effects on cancer development including:10Previous studies show that antioxidants are protective against chemically induced lung cancer.8-10For example, NAC prevented the induction of lung tumors when supplemented to the diet of mice both before and after injection of a carcinogen. The reseachers also noted that their results "…rule out that NAC may behave as a tumor promoter…"8 Previous research demonstrates that NAC has an impressive array of mechanisms and protective effects on cancer development including:10
· Inhibition of genotoxicity and cell transformation
· Positive effects on gene expression and signal transduction pathways (eg, an increase in p53 expression, modulation of TNF-alpha, and decrease the activity of transforming growth factor- beta[TGF-beta])
· Modulation of apoptosis
· Inhibition of tumor promotion and progression
· Inhibition of cell proliferation
· Inhibition of invasion and metastasis of cancer cells
Furthermore, scientific publications and clinical trials examining actual human data, as opposed to conjecture and hypothetical commentary,demonstrate the benefits of antioxidants in cancer. The author appears to ignore existing research that does not support his hypothesis. Although more work needs to be done, a significant body of published scientific literature demonstrates antioxidants increase survival, tumor response, or both. For example:
· A systematicreview conducted by Block, et al. in 2007 of only randomized, controlled clinical trials that reported survival and/or tumor response had the following conclusion: "None of the trials reported evidence of significant decreases in efficacy from antioxidant supplementation during chemotherapy. Many of the studies indicated that antioxidant supplementation resulted in either increased survival times, increased tumor responses, or both, as well as fewer toxicities than controls…"11
· A review article published in 2007 by Simone, et al. concludes, "Since the 1970s, 280 peer-reviewed in vitro and in vivostudies, including 50 human studies involving 8,521 patients, 5,081 of whom were given nutrients, have consistently shown that non-prescription antioxidants and other nutrients do not interfere with therapeutic modalities for cancer. Furthermore, they enhance the killing of therapeutic modalities for cancer, decrease their side effects, and protect normal tissue. In 15 human studies, 3,738 patients who took non-prescription antioxidants and other nutrients actually had increased survival.12
· In a 2004 review article by Prasad et al., the authors propose "that an active nutritional protocol that includes high doses of multiple dietary antioxidants and their derivatives(vitamin C, alpha-tocopheryl succinate, and natural beta-carotene), but not endogenously made antioxidants (glutathione- and antioxidant enzyme-elevating agents), when administered as an adjunct to radiation therapy, chemotherapy, or experimental therapy, may improve its efficacy by increasing tumor response and decreasing toxicity. Experimental data and limited human studies suggest that use of these nutritional approaches may improve oncologic outcomes and decrease toxicity."13
· Several individual studies suggest antioxidant nutrients such as tea polyphenols, curcumin, quercetin, selenium, and others have synergistic effects with conventional oncology treatments(chemotherapy/radiation). 14-17
· A 2007 article by Simone, et al. provides an extensive list of studies demonstrating the benefits of antioxidant nutrients in cancer chemotherapy and radiation.12 See the table below titled "The Effects of Nutrients on Patients Receiving Systemic Treatment and/or Radiation Treatment." For example,
o A randomized, double-blind, placebo-controlled trial assessed the efficacy of glutathione (GSH) in the prevention of cisplatin induced neurotoxicity. The authors found an improved response rate (76% [20%complete response] in the GSH group and 52% [12% complete response] in the placebo group). The trial also confirmed preliminary reports about the lack of reduction in activity of cytotoxic drugs induced by GSH.18
o In a study of 50 consecutive patients with untreated stage III or stage IV ovarian cancer, patients were treated with 2c ycles of cisplatin, carboplatin and glutathione (2,500 mg before chemotherapy). Fifty-four percent of patients had a complete response, there were fewer side effects, and the survival was better than expected.19
o In a study of 17 patients with squamous cell carcinoma of the upper digestive tract, patients were treated with radiotherapy, antioxidants, and beta-alanine (an amino acid). After observing the patients for 63 months, they were found to have decreased side effects from radiotherapy, improved physical comfort, and increased survival compared to a reference population of patients with squamous cell carcinoma of the upper digestive tract.20
o In a study of 32 patients with breast cancer that spread to axillary lymph nodes, patients were given conventional surgical and therapeutic treatments, as well as daily supplements of vitamin C (2,850 mg), vitamin E (2,500 IU), beta-carotene (32.5 IU), selenium (387 μg),essential fatty acids (1.2 g gamma linolenic acid and 3.5 g omega-3 fatty acids), and coenzyme Q10 (90 mg). Compared to patients who received conventional treatment only, this group had decreased rates of recurrence and increased quality of life, survival rates, and partial remission rates.21
o In a randomized trial, patients with metastatic breast carcinoma treated by chemotherapy were administered vitamin A. The daily doses (given indefinitely) ranged from 350,000 to 500,000 IU according to bodyweight. A significant increase in the complete response rate was observed.22
· Men who took vitamin E supplements for 10 years or more had a 30% lower risk of bladder cancer.23
· People who took multivitamin supplements daily for 10 years had one-half the risk of colon cancer, compared to those who did not take multivitamins.24
· In an observational study of 50 consecutive patients with untreated stage III or stage IV ovarian cancer, patients were treated with 2 cycles of cisplatin (40 mg/m2), carboplatin (60 mg/m2),and glutathione (2,500 mg before chemotherapy). Fifty-four percent of patients had a complete response, fewer side effects were noted, and survival was better than expected (median survival >48 months).25
· People with diets high in vitamin C have about half the risk for many types of cancer compared to people with low vitamin C diets.26,27
· People with the highest dietary intakes of vitamin C, beta-carotene, and vitamin E had a 68% lower risk of lung cancer.28
· A systematic literature review and meta-analysis suggest a modest reduction in endometrial cancer risk with higher consumption of beta-carotene, vitamin C, and vitamin E from food sources, based on data from case-control studies. The authors estimated a 12% reduction in endometrial cancer risk per 1,000 mcg/1,000 kcal for beta-carotene, a 15% decreased risk per 50 mg/1,000 kcal vitamin C, and a 9% reduction in risk per 5 mg/1,000 kcal vitamin E.29
Also,antioxidant nutrients provide other mechanisms of action that have proven benefits in cancer:
· Laboratory and animal data have revealed that antioxidants increase cancer cell differentiation and/or apoptosis and growth inhibition by several additional complex mechanisms not related to antioxidant action.30,31 As outlined by Simone et al:12
· "Antioxidants inhibit gene expression and/or activity of p53 mutant, c-myc, H-ras, Bcl2, c-neu, c-erbB2, vascular endothelial growth factor (VEGF), phosphotyrosine kinase, and protein kinase C."
· "Vitamin E reduces the expression of VEGF and thus acts as an anti-angiogenic factor."
· "Antioxidants selectively inhibit repair of radiation damage of cancer cells but protect normal cells when antioxidants are used before, during, and after radiation—there are no published studies that show antioxidants protect cancer cells against radiation."32
Oncologists prescribe antioxidant medications to their cancer patients.
If antioxidants negatively affected cancer patients, the following two strong antioxidant medications would not be so widely prescribed by oncologists:
- Amifostine is an antioxidant prescription drug that reduces several forms of radiation and chemotherapy toxicity without reducing effectiveness. In fact, preliminary trials have demonstrated enhanced response rates to radiation therapy in oncology patients taking the drug.33
- Dexrazoxane protects against chemotherapy induced free radical damage to the heart. Overall, clinical trials have not shown a significant difference in response rates, time to disease progression or survival times in patients receiving chemotherapy with dexrazoxane compared tochemotherapy alone.34
Ill-informed media reporters have incited great concern among the public by improperly contextualizing Sayin's findings. This preclinical work simply provides evidence about the effects of synthetic vitamin E and N-acetylcysteine in mutant mice under specific laboratory conditions. Findings from this experimental study cannot be extrapolated to humans.
Although the media machine prefers fear mongering to accurately reporting scientific developments, Life Extension members can rest assured that any news stories based upon this research cannot be directly translated to humans. We continue to recommend that aging individuals consume antioxidants to obtain meaningful health benefits that has been elucidated byresearch conducted in human subjects.
1. Gaziano JM, Sesso HD, Christen WG,et al. Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA: the journal of the American Medical Association. Nov 142012;308(18):1871-1880.
2. Kline K, Lawson KA, Yu W, Sanders BG. Vitamin E and cancer. Vitamins and hormones. 2007;76:435-461.
3. Blatt DH, Pryor WA, Mata JE,Rodriguez-Proteau R. Re-evaluation of the relative potency of synthetic and natural alpha-tocopherol: experimental and clinical observations. The Journal of nutritional biochemistry. Jul 2004;15(7):380-395.
4. Burton GW, Traber MG, Acuff RV, et al. Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. The American journal of clinical nutrition. Apr 1998;67(4):669-684.
5. Jiang Q, Christen S, Shigenaga MK, Ames BN. gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. The American journal of Clinical nutrition. Dec 2001;74(6):714-722.
6. Campbell SE, Stone WL, Lee S, et al.Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines. BMC Cancer. 2006;6:13.
7. Chan AC. Normal plasma vitamin E concentration. The Biochemical journal. Jun 1 1989;260(2):623.
8. De Flora S, Astengo M, Serra D,Bennicelli C. Inhibition of urethan-induced lung tumors in mice by dietary N-acetylcysteine. Cancer letters. Sep 1986;32(3):235-241.
9. van Zandwijk N. N-acetylcysteine for lung cancer prevention. Chest. May 1995;107(5):1437-1441.
10. De Flora S, Izzotti A, D'Agostini F, Balansky RM. Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points. Carcinogenesis. Jul 2001;22(7):999-1013.
11. Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer treatment reviews. Aug 2007;33(5):407-418.
12. Simone CB, 2nd, Simone NL, Simone V, Simone CB. Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 2. Alternative therapies in health and medicine. Mar-Apr 2007;13(2):40-47.
13. Prasad KN. Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity. Integrative Cancer therapies. Dec 2004;3(4):310-322.
14. Way TD, Lee HH, Kao MC, Lin JK. Black tea polyphenol theaflavins inhibit aromatase activity and attenuate tamoxifen resistance in HER2/neu-transfected human breast cancer cells through tyrosine kinase suppression. European journal of cancer. Sep 2004;40(14):2165-2174.
15. Nessa MU, Beale P, Chan C, Yu JQ, Huq F. Studies on combination of platinum drugs cisplatin and oxaliplatin with phytochemicals anethole and curcumin in ovarian tumour models. Anticancer Research. Nov 2012;32(11):4843-4850.
16. Thangasamy T, Sittadjody S, Mitchell GC, et al. Quercetin abrogates chemoresistance in melanoma cells by modulating delta Np73. BMC cancer. 2010;10:282.
17. Clark LC, Combs GF, Jr., Turnbull BW,et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA : the journal of the American Medical Association. Dec 25 1996;276(24):1957-1963.
18. Cascinu S, Cordella L, Del Ferro E, Fronzoni M, Catalano G. Neuroprotective effect of reduced glutathione oncisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Jan 1995;13(1):26-32.
19. Bohm S, Oriana S, Spatti G, et al. Dose intensification of platinum compounds with glutathione protection as induction chemotherapy for advanced ovarian carcinoma. Oncology. 1999;57(2):115-120.
20. Rougereau A, Sallerin T, Chapet J,Robin JC, Rougereau G. [Adjuvant treatment of patients with neoplastic lesions using the combination of a vitamin complex and an amino acid. Apropos of a series of 17 cases of epidermoid carcinoma of the upper aerodigestive tract]. Annales de gastroenterologie et d'Hepatologie. Mar-Apr 1993;29(2):99-102.
21. Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in 'high risk' patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Molecular aspects of medicine. 1994;15 Suppl:s231-240.
22. Israel L, Hajji O, Grefft-Alami A, et al. [Vitamin A augmentation of the effects of chemotherapy in metastatic breast cancers after menopause. Randomized trial in 100 patients]. Annales de medecine interne. 1985;136(7):551-554.
23. Michaud DS, Spiegelman D, Clinton SK, Rimm EB, Willett WC, Giovannucci E. Prospective study of dietary supplements,macronutrients, micronutrients, and risk of bladder cancer in US men. American Journal of epidemiology. Dec 15 2000;152(12):1145-1153.
24. White E, Shannon JS, Patterson RE.Relationship between vitamin and calcium supplement use and colon cancer. Cancer epidemiology, Biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Oct 1997;6(10):769-774.
25. Bohm S, Oriana S, Spatti G, et al. Dose intensification of platinum compounds with glutathione protection as induction chemotherapy for advanced ovarian carcinoma. Oncology. 1999;57(2):115-120.
26. Block G. Vitamin C and cancer prevention: the epidemiologic evidence. The American journal of clinical nutrition. Jan 1991;53(1 Suppl):270S-282S.
27. Dickinson A, Shao A. MULTIVITAMINS AND OTHER DIETARY SUPPLEMENTS FOR BETTER HEALTH. 2006;http://www.crnusa.org/pdfs/CRN_PostitionPaper_MULTIVITAMIN.pdf.
28. Yong LC, Brown CC, Schatzkin A, et al. Intake of vitamins E, C, and A and risk of lung cancer. The NHANES I epidemiologic follow up study. First National Health and Nutrition Examination Survey. American Journal of Epidemiology. Aug 1 1997;146(3):231-243.
29. Bandera EV, Gifkins DM, Moore DF, McCullough ML, Kushi LH. Antioxidant vitamins and the risk of endometrial cancer: a dose-response meta-analysis. Cancer causes & control : CCC. Jul 2009;20(5):699-711.
30. Prasad KN, Kumar A, Kochupillai V, Cole WC. High doses of multiple antioxidant vitamins: essential ingredients in improving the efficacy of standard cancer therapy. Journal of the American College of Nutrition. Feb 1999;18(1):13-25.
31. Prasad KN, Cole WC, Kumar B, Prasad KC. Scientific rationale for using high-dose multiple micronutrients as an adjunct to standard and experimental cancer therapies. Journal of the American College of Nutrition. Oct 2001;20(5 Suppl):450S-463S; discussion 473S-475S.
32. Prasad KN, Cole WC, Kumar B, Che Prasad K. Pros and cons of antioxidant use during radiation therapy. Cancer Treatment Reviews. Apr 2002;28(2):79-91.
33. MDConsult. Amifostine. 2009; http://www.mdconsult.com/das/pharm/body/396347852-5/1398815447/full/21.Accessed 1/17/2013.
34. MDConsult. Dexrazoxane 2013;http://www.mdconsult.com/das/pharm/body/396347852-5/0/full/176?infotype=1.Accessed 1/17/2013.
35. Hoenerhoff MJ, Hong HH, Ton TV, Lahousse SA, Sills RC. A review of the molecular mechanisms of chemically induced neoplasia in rat and mouse models in National Toxicology Program bioassays and their relevance to human cancer. Toxicologic pathology. Dec 2009;37(7):835-848.
36. Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nature Medicine 10, 789–799 (2004)doi:10.1038/nm1087. Available at: http://www.nature.com/scitable/content/cancer-genes-and-the-pathways-they-control-14019136Accessed 1/31/2014.
37. Lodish H, Berk A, Zipursky S, et al.New York: W. H. Freeman. Molecular Cell Biology. 4th edition. Available at: http://www.ncbi.nlm.nih.gov/books/NBK21662/Accessed 1/31/2014.
38. Cornell University. The Biology of Breast Cancer. Available at: http://envirocancer.cornell.edu/factsheet/general/fs5.biology.cfmAccessed 1/31/2014. 1997.
39. van der Worp HB, Howells DW, Sena ES,et al. Can animal models of disease reliably inform human studies? PLoS Medicine. Mar 2010;7(3):e1000245.
40. Scalbert A,Johnson IT, Saltmarsh M. Polyphenols: antioxidants and beyond. The American Journal of Clinical Nutrition. Jan 2005;81(1 Suppl):215s-217s.


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subset: commoncrawl


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Hot tags Animals Botany Climate Change Earth Sciences
Science subject and location tags
Articles, documents and multimedia from ABC Science
RSS | MapOffbeat
Texting makes you walk 'like a robot'
Thursday, 23 January 2014
It's official: texting could send you off track and make you walk 'like a robot', increasing your chance of falling over, say Australian researchers.
Sea slug drops penis after sex
Wednesday, 13 February 2013
Weird and wonderful A sea slug has taken the idea of a throw-away society to new levels with the discovery it discards its penis after sex, then grows a new one to use the next day.
Wee small hours of the morning explained
Wednesday, 2 May 2012
Scientists have pinpointed a protein that helps explain why the elderly frequently have to get up in the night to urinate.
Robots teach themselves to talk the talk
Tuesday, 31 May 2011
Australian robots have begun talking to each other, in a language of their own devising.
Vortices push tea up hill
Tuesday, 31 May 2011
Scientists believe they've discovered a process that allows water to flow up hill.
Singing Aussie whales top of the pods
Friday, 15 April 2011
Scientists say mating songs sung by Australian humpbacks go on to spread to whale populations all over the South Pacific.
Whale snot, bat sex win 2010 IgNobels
Friday, 1 October 2010
Researchers who used a remote-controlled helicopter to collect whale snot, documented bats having oral sex and showed swearing makes you feel better when you stub a toe were among the winners of this year's IgNobel prizes.
Da Vinci's ornithopter takes flight
Friday, 24 September 2010
Canadian engineering students say they have brought Leonardo Da Vinci's sketch to life and flown an engineless aircraft that stays aloft by flapping its wings like a bird.
Seven hours the magic number for sleep
Monday, 2 August 2010 20
People who sleep more or fewer than seven hours a day, including naps, are increasing their risk for cardiovascular disease, a US study shows.
Scientists think chicken came first
Thursday, 15 July 2010
British scientists think they have the answer to the age-old question of whether the chicken or the egg came first.
Gas-mask bra leads IgNobel awards
Friday, 2 October 2009
Engineers who invented a bra that converts into a gas mask and Irish police officers who mistakenly wrote tickets to 'Driver's Licence' have lead the IgNobel prizes for 2009.
Pen-clicking 'should be investigated'
Wednesday, 1 April 2009
Incessant pen-clicking by hospital workers could be a Geiger-counter for stress and should be investigated, says a medical blogger.
Colossal squid's true size revealed
Friday, 2 May 2008
The exact size of a frozen colossal squid that was thawed this week has been revealed by New Zealand officials.
Columbus spread syphilis, says new study
Tuesday, 15 January 2008
Christopher Columbus spread syphilis from the New World to Europe, according to new genetic evidence, which has revived a centuries-old debate about the origins of the disease.
Ghosts in the mind
Thursday, 27 November 2003
Haunted Houses, silent spectres and bellowing banshees have startled and spooked innocent victims among the living for centuries. But does the world of the 'un-dead' really exist or do we create it all 'in-head'? Elaine Mulcahy enters the conflicting worlds of science and the supernatural to investigate


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Wich is the best for the money? What type of mounting? Thanks
Wich is the best for the money? What type of mounting? Thanks
Oh, this will be helpful. I can't give name, link, product code --
I'm not at home but got an illuminated 2x scope for about $50 that WORKS!
Can be used both eyes open but still gives some magnification.
There is no nonsense so errant that it cannot be made the creed of the vast majority by adequate governmental action. -- Bertrand Russell
"Never attribute to malice that which can be adequately explained by stupidity." Robert J. Hanlon
Sounds like a possible. Anxious to see it. Thanks
TRU-GLO,I got a 2x at Dicks for $80 that seems to work on my Browning brake down 22 rifle.
SOON-We already lost the war. You are the resistance.
I went to DPHarms.com and picked up a side scope mount with dual rails(the kind that you slide onto the side) for $20.00 and it locks in.
Then I went to Walmart and got the BSA red dot for $40.00 and it works just fine.
To mount it I had to get a weaver to 22 adapter.$15 at a gun show.
SOON-We already lost the war. You are the resistance.
Mine was red only and 3MOA dot W/intagrated weaver mount.It was the last one,display model at Dicks about 18 months ago.Silver in color 42mm-2x.
SOON-We already lost the war. You are the resistance.
my romy with the sidemount rail and cheap-o bsa walmart red dot. the best part is that the scope rail attaches and detaches so easily, the mount is never a burden;that said-I rarely use it and only bought it because i thought it would look cool.. more accurrate than the iron sights tho.
I also bought what was advertised as a green laser from opticsplanet but 2 months later i got a red dot that barely works. when asked about their return policy, i had to pay the shipping and some buillshit 15% restock fee-FOR SOMETHING THAT I DIDNT EVEN ORDER.
that is ALSO only on there because I thought it would be cool...a bit overrated. perhaps if i had one that actually worked and was mounted under the barrel?
..yeah-thats the ticket.


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Monday, July 28, 2014
Berkeley County Council has passed its budget for the current fiscal year after months of wrangling and a slew of last-minute amendments that, in the words of one councilman, dig into the fund balance.
The $61 million budget is a 0.5 percent increase over last years $58 million budget, and reflects an increase in projected revenue. The tax bill wont look any different from the previous year because of the budget, according to county Real Property Director Wilson Baggett.
The budget passed without dissent but with 11 amendments during Mondays regular meeting of council. Last year, it took until September for the council to pass the $58-million budget. The fiscal year closed at the end of June without a new budget after council deferred it during the June 23 meeting.
This years amendments included:
Eliminating debt owed to the county by Cypress Gardens
Using accommodation fee fund to pay for a $25,000 marketing campaign for Cypress Gardens as a wedding venue
Changing the overtime policy to time-and-a-half for detention center employees to the tune of $435,000 out of the fund balance
Purchasing 15 law enforcement replacement vehicles at $571,000 out of the contingency fund
Using $115k from the fund balance for contribution to retirement fund that has run into deficit
The only amendment proposed that did not pass was an immediate 3 percent merit raise for county employees. Councilman Caldwell Pinckney made the amendment and pointed to all of the other amendments taking money from the fund balance.
If we are going to dig into our fund balance, lets dig a little deeper. Lets give something to our employees, Pinckney said. Employees are the backbone of the county.
After the amendment failed, Councilman Tim Callanan made an amendment that a merit raise be looked at after Jan. 1, 2015. That amendment passed.
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From Trojan to Tiger
Carlos Watkins has made a successful transition from Chase Trojan to Clemson Tiger. Now that the college football season has ended, the Rutherford County native took some time to reminisce about his first year on the collegiate gridiron.
"Man, it's like I'm living a dream," said Watkins. "I've always wanted to play college football, but to play in front of 80,000 people. Wow. From the first time I stepped on the field until now, it has just been an amazing experience."
Watkins is quick to admit that even though his experiences were "amazing," they were not easy.
"Playing college football is hard work," he said. "It's not just going out there and playing a game on Saturday. There is so much stuff that goes on during the week to get ready for the game; playing football is the easiest part of the week. It's definitely the most fun."
That hard work continues even after the final whistle of the season's final game.
"Even in the offseason you are lifting every day, trying to get faster and stronger," Watkins said. "You don't get a break. You have to stay focused on football all year long."
Having to focus on football year-round is only one major difference Watkins had to adjust to when coming to Clemson.
"The speed and how physical the game is were the biggest things I had to get used to ,"said Watkins, who plays defensive tackle "In high school, I could just pick people up, throw them out of the way and get to the ball. I can't do that here because guys weigh 330 pounds and run at 4.3 or 4.4 (speed). It took a while to get used to but I came to camp and started working on my technique, so the adjustment wasn't as hard as it could have been."
One factor that helped Watkins adjust to the college game was his familiarity with the Tigers' defensive scheme.
"We run the same scheme at Clemson that we did at Chase," Watkins said. "It definitely helped not having to learn a new system. All I had to focus on was gap control which was totally different. In high school, I could just fly around and hit people. Now I have to be disciplined and stay in my gap."
While adjusting to the rigors of college football has been a challenge for Watkins, life in the classroom has come much easier.
"Honestly, classes are not as hard as I thought they would be," he said. "The biggest thing I had to get used to was all the walking. Sometimes my classes were several miles apart. Balancing class and football was hard sometimes, but after awhile you get used to it and it becomes part of your routine. It's more of a mental thing than anything else."
That hard work and discipline on the field and in the classroom paid off as Watkins saw action in 11 of Clemson's 13 contests in 2012. The most vivid memory for Watkins, however, did not come from a particular game. It occurred before he took the field for Clemson's home opener versus Ball State.
"The time I was getting ready to rub the rock and run down that hill for the first time, I won't lie, I was so nervous," Watkins said. "I just kept saying to myself 'don't trip and fall in front of all these people'. Once I got down there and stepped on the field though, I wasn't nervous. I found my rhythm and just started playing football. It was one of the best experiences of my life."
Statistically, Watkins most predictive game of 2012 came on Oct. 20 in a 38-17 Clemson win over Virginia Tech. In that contest he garnered two solo tackles and assisted on another. For the season, Watkins played an estimated 100 to 125 snaps and finished with 13 total tackles, five of which were unassisted.
Of all those tackles, it is the one he didn't make that is the most vivid in Watkins mind.
During Clemson's 25-24 upset of LSU in the Chic-Fil-A Bowl, he nearly came away with a sack of LSU quarterback Zach Mattenberger.
"I had him wrapped up but he just got away," Watkins said. "Guys are just so much stronger at this level that sometimes that happens...I'll take the win though," Watkins continued. "Beating LSU was the best moment we had as a team all year. No one expected us to win and to do it on a last second field goal was great. I just enjoyed celebrating with my teammates that night."
The celebration did not last long, however, as Watkins and the rest of his Tiger teammates are already preparing for a 2013 season that is loaded with expectations.
"Last year was a great learning experience for me," said Watkins. "Honestly, I wanted to see more playing time, but it was helpful just to sit back and learn. This year, I want to be an impact player on a national championship team. Coach (Dabo) Sweeny always tells me to let it all go and not hold anything back and that's exactly what I want to do."
Chase coach Daniel Bailey, who attended most of Clemson's home games this season, believes that Watkins can become more than just an impact player. "From what I've seen this year, I think Carlos can be a household name in college football, not just in this area, but in the country," said Bailey. "He is that talented."
While Bailey and other friends and family were watching Watkins play this season, Watkins was in turn keeping tabs on the Trojans football team.
"I would call (younger brother) Tray every Friday night to find out how they did," said Watkins. "I wanted to be out there helping them so bad, but especially in that playoff game against Shelby. I was asking for updates every 30 seconds so it felt like I was at the game. I felt so bad for the team when they lost. I thought they were finally going to beat Shelby."
Watkins ties to Rutherford County remain strong in other ways as well.
"I am very blessed and proud to say I am from Rutherford County and that doesn't change just because I play college football," he said. "One of the main reasons I came to Clemson is so I could stay close to home and everyone could come watch me play. The support has encouraged me so much I am going to do my best to represent the folks back home well by helping to win a national championship this year."


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Report & photos by Keith Shampine (Mouse over photos to read caption)
CONCORD, N.C. – The 2013 WKA VEGA / TS Racing Road Racing Series driven by Mazda Grand Nationals went off this past weekend at the beautiful VIRginia International Raceway near Danville, Va., marking round six of this year's national series and the third round of the Woodbridge Kart Club's regional road racing series.
A strong turnout of 390 entries made the event a success for WKC and WKA, and it marked the second consecutive national road race that attracted an entry count around 400. The Mid-Ohio Nationals in June surpassed the 400-entry plateau.
Road Racing teams from around the country – including Florida, Oklahoma, Texas, Massachusetts, the all parts of the Midwest and up and down the Mid-Atlantic region – moved into the VIR paddock Thursday evening and embarked on a full day of practice Friday.
A handful of local-option races took place Friday evening, the headliner being the Yamaha Sportsman Special money race that paid $300 to Chris Larson of Oklahoma, who overtook Ryan Hatcher late in the race for the top prize.
Mother Nature had officials and competitors concerned Saturday morning with dark clouds showing their face and reports of steady rain in Martinsville, Va., about 35 miles from VIR. People around the pit area predicted only one or two races would get in before the rain hit, however, while dark clouds loomed throughout the day, the rain didn't hit until the end of race group No. 6.
The sixth race was able to run the full 45-minute distance, but while retired karts and drivers were getting picked up before the start of race No. 7 – the day's final event – rain picked up and dampened the entire VIR facility. Unfortunately for the shifter karts and TaG racers set to run the day's final race, it had to be cancelled because of the steady rain falling.
Cloud cover and some intimidating clouds greeted racers Sunday morning but the skies cleared late morning and approximate 90-degree temperatures made it the hottest condition for a road race thus far in 2013.
Sunday's six race groups were completed in their entirety, and most teams were loaded up and set to embark on their journey home by 3 or 4 in the afternoon.
Here's a rundown of the weekend's race at the Road Race Grand Nationals.
Saturday Race 1
Randy Fulks scored the weekend's first Grand National win in Sleeper Racing Team 100cc Controlled Spec 1. Fulks, who's won a number of races in the Spec division in recent years, bested former WKA Triple Crown champion Adam Myers for the win. Ageless veteran Jim Fry was third, Rick Fulks fourth and Sean O'Shea completed the top five of seven starters.
Matt Michel crossed the stripe first in Hoosier Racing Tire Yamaha Sportsman Lite but was disqualified in post-race tech. Michel's misfortune gave the win to CKI racer Zack Clark, who recently competed in his first WKA Gold Cup event at G&J Kartway in Camden, Ohio. Tim Linthicum was second, Brian Ellis third and Massachusetts' Fran Mazzucotelli fourth.
Ryan Hatcher traveled to VIR from his Oklahoma home and won Dart Kart Club 100cc Pipe Heavy. Ohio's Mallory Davis finished second.
Saturday Race 2
Jeff Metter and his 250cc-powered super kart had the fast Formula 125 racers covered in Unlimited Final 2. Metter scored the big win over Arkansas' Brian Wilhelm. Michael Lattos was third, Mitch White fourth and Derek Cuthbertson fifth.
The largest class of the day belonged to Stock Honda 1, which started 24 Honda-powered shifter karts. Veteran Byron "Bear" Rothenhoefer dominated the race, pulling away for the Grand National triumph over Sam Bocchino. John Sullivan was third, Philip Davis fourth and Bill Pyles fifth. Stephen Flatt had a terrific run to cross the stripe second but was DQ'ed in post-race tech. Rothenhoefer won a set of VEGA XH tires for his win, which was posted by series sponsor TS Racing.
Saturday Race 3
This race was red-flagger and called complete just after halfway due to an accident involving Toni Alexander. Toni was sore but otherwise OK.
Keith Buffo added another national triumph to his collection with the win in TaG Final 1. The Massachusetts racer won over Gabriel Robleto. Justin Rodriguez was third, Joseph Brizzolara fourth and Clark A Gaynor fifth.
Adam Myers dominated the WKA Sprint Final 1 race with a big win over New Englander Ted Carbonaro. WKC regular Derek Somers was third, Eric Stockford fourth and Jim Sorrentino fifth.
MGM Chassis racer Zachary Linsell continued to prove he's the top 4-cycle road racer in the country with his win in Hoosier Racing Tire Animal Sprint 335. Linsell scored the win over fellow MGM racer Sam Sheckells. Austyn Flurer was third, Blake Beattie fourth and Georgia's Brent Hadden fifth in the 13-kart field.
Jonathan Tedder continued his fine 2013 season with a convincing win in Animal Sprint 385. Tedder pulled away for an easy win over Andrew Boyer. Robert Garland was third, William Lewis fourth and Alexander credited with fifth.
Jeff Futch won the Open Sprint 1 local option and Rick Gilmore won the WKC Vintage Limited local option over Dwain Parks and Dick Charest.
Saturday Race 4
One of the most competitive races of the day was AM Motorsports Yamaha Sportsman Heavy, which started 15 karts and many of the best enduro road racers in the country. Woodbridge Kart Club regular Jermie Bolt, racing in his home state, fended off the outsiders for a big Grand National triumph.
Matt Michel was second but was disqualified in post-race tech. Oklahoma's Chris Larson crossed the stripe just behind Bolt for the runner-up position. Ryan Hatcher was third, Evan Bolt fourth and Wild Bill Holder fifth.
Wisconsin's Don Chrzan had a terrific weekend and scored the win in The Agile Group, Inc. 100cc Controlled Final 1. Chrzan won over Sean O'Shea and Michael Tracy.
Saturday Race 5
WKC hosted road races always feature a good field of Streeter Super Stands Stock Leopard competitors and VIR was no exception. WKC regular Rebecca Taylor earned the big win over fellow club racer Clark A Gaynor. New Jersey's Bryan Danieli was third, Don Guilbeault fourth and Aamir Hyder fifth. Fourteen karts took the green.
Michael Holman earned a big win in Heiser Trailer Leasing Yamaha Sportsman Sprint Final 1. Holman took advantage of Zack Clark spinning early in the race. Clark kept it going, however, but never could close within three seconds of Holman. Ohio's Andy Leighininger followed Holman and Clark to take third. AJ Ellis was fourth and Stacey Holewski fifth.
Andrew Boyer won Yamaha Sprint Lite over Florida's Jimmy Duguay. James Vandermuelen was third.
Jonathan Tedder won his second Grand National Eagle of the day with his triumph in Animal Limited Modified 385. Ben Morris was second, Charles Wilbur third and Toni Alexander fourth.
North Carolina's Chris Kuley picked up another Animal Junior win, this time over Daniel Ring.
Alex Frazer bested JT Coupal and Kyle Cuthbertson in Junior Sprint Lite.
Desmond Lewis and Joe Cuslidge were Clone winners. Lewis took 335 and Cuslidge won 385 over Darren Greene.
Kamron Darling won LO206 385 and Bill Johnson won the Vintage USA 1 local option.
Saturday Race 6
Kelly Lawrence continues to run fast with his Komanche Formula 125 enduro. Lawrence had the speed again at VIR to best a competitive field. Michael Lattos was second, Mitch White third, Fran Mazzucotelli fourth on a 135cc open and Brian Wilhelm retired early and was credited with fifth.
Alabama's Robby Harper earned another B Stock victory. Harper won the Grand National over Craig Keller. Ben Eberhardt was third and Scott Goodman fourth.
Don Chrzan scored win No. 2 on the day in KALL Racing Formula 100 Final 1. Chrzan dominated the race and won over North Carolina's Paul Wyzga. Bill Miller was third, Michael Tracy fourth and Travis Miller fifth.
CKI racer Chris Larson scored the Dart Kart Club Yamaha Medium win over Brian Ellis, who's been stationed in Germany recently with the US Air Force. Florida's Lance Yunck, competing in his third class of the day, was third. James Rupert and Dan Stowell rounded out the top five.
Saturday Race 7
As noted earlier, rain hit just before the day's final race was set to go green and unfortunately for the 15 racers who waited all day to race, the event was rained out and competitors were awarded rain points.
Sunday Race 1
Jeff Metter made it two for two in Unlimited competition at VIR with his win in the Sunday morning weekend capper. Metter won an eventful race that saw him and Robby Harper jump out to a big lead before Harper dropped out with mechanical issues around the 10-minute mark. Brian Wilhelm spent half the race to run down Metter only to spin in turn one as he looked low on the leader.
Then Scott Goodman ran down Metter and passed him for the lead. After leading several laps, Goodman retired from the race, handing the lead back to Metter, who went on to the victory. Michael Lattos was second, Mitch White third, Scott Hodges fourth and Harper was credited with fifth.
Brian Fisher and Stevie Young got a break in Stock Honda 2 when Saturday Stock Honda winner Bear Rothenhoefer threw a chain on the start. Fisher and Young pulled out to a big lead and crossed the finish stripe side by side with Fisher edging out the Virginia Tech student. Mark Nagy edged Greg Heberle for third. Dan Chalk rounded out the top five of 23 starters, the day's largest class.
Sunday Race 2
A host of classes took the green after the Sunday mandatory quiet hour.
Mike Kavanaugh scored the win in TaG Final 2 over Justin Rodriguez. Joseph Brizzolara was third, Gabriel Robleto fourth and Timothy Ferraro fifth.
New York's Adam Myers swept WKA Sprint with his win in Final 2. Myers won by a comfortable margin over Massachusetts' Jim Sorrentino. Ted Carbonaro was third, Eric Stockford fourth and George Williams fifth in the eight-kart field.
Eighteen karts started MGM / Moon Power Animal Sprint 360 to make it the weekend's largest class other than Stock Honda 1 and 2. MGM racers Zachary Linsell and Sam Sheckells pulled away from the rest of the field and put on a good show for fans. Linsell led early before Sheckells took the lead and led most of the second half of the race.
Sheckells led Linsell down the roller coaster coming to the checkered but Linsell gained a draft off Sheckells and swung past him coming to the checkered. Blake Beattie was third, Joey Kuley fourth and Ben Thomason rounded out the top five. Austyn Flurer ran in the pack with Beattie, Kuley and Thomason but had to settle for sixth.
Darlington, South Carolina's Rob Garland II scored the Grand National win in Animal Sprint 410. Garland won over Robert Garland and Steve Jeffers. Rich Dreher was fourth and Steve Johnson fifth.
Daniel Ring won Animal Jr Sprint Heavy when Chris Kuley retired with an exhaust problem on his Briggs Animal.
Jeff Futch won the Open Sprint 2 local option and Duane Eberhart won over Robert Anderson in the Vintage Euro local option.
Sunday Race 3
One of the weekend's best races belonged to Sunday's third group. Randy Fulks failed to get off the grid for 100cc Controlled Spec 2, leaving the race to Adam Myers, Sean O'Shea, Jim Fry and Rick Fulks.
Myers led early before dropping out. Rick Fulks was running with Jim Fry and O'Shea before spinning in turn one. Fulks continued and ran down Fry and O'Shea. The three battled hard throughout the second half of the race before Fry spun in turn three on the last lap. Fulks and O'Shea battled it out over the last lap with Fulks edging O'Shea at the line for the Grand National Eagle. O'Shea took second, Jim Fry third, Lance Fry fourth and Myers fifth.
Ian E Morgan won 100cc Controlled Final 2 over Michael Tracy and Don Chrzan.
Seventeen racers started Competition Karting Inc. Yamaha Sportsman Medium, which awarded a set of Hoosier tires to the victory. The early lead pack included Ryan Hatcher, Matt Michel, Chris Larson, Brian Ellis and Zack Clark until a spin in turn one only two laps into the race took out Michel and Clark and cost Larson and Ellis valuable time.
Hatcher was able to avoid the incident and run away for a 27-second dominating win. Larson recovered to pass a number of competitors to make it back to second place. Wild Bill Holder took third, Saturday Sportsman Heavy winner Jermie Bolt fourth and Ellis fifth.
Sunday Race 4
Sam Bocchino picked up the win in CIK 125 Shifter Final 2 over Birel racer Steven Rougeou. Donald Santini was third.
Dan Chalk won WKA 125 Shifter Final 2 over Philip Payne.
Chris Hines barely edged teammate Keith Buffo to win TaG Heavy Final 2. Adrian Dale was third and Michael Hines fourth.
Sunday Race 5
Clark A Gaynor won the Streeter Super Stands Stock Leopard Sprint Final 2 race and earned a set of VEGA XH tires posted by TS Racing. Gaynor won over Brandon Taylor, who recovered after getting off the grid late. Bernie Adamson was third, Walter Troup fourth and defending Stock Leopard national champion Jeff Wesell fifth in the 14-kart field.
Zack Clark and Michael Holman swapped positions from Saturday's Yamaha Sportsman Sprint main event. Clark, who finished second to Holman on Saturday, won this one for his second victory of the weekend. Holman had to settle for second, Jeff Leighninger third, AJ Ellis fourth and Andy Leighninger fifth.
Florida's Jimmy Duguay won Yamaha Sprint Heavy.
Ben Morris bested Charles Wilbur to win Animal Limited Modified 360.
New York's JT Coupal earned a Grand National victory with his win over Alex Frazer in Team Finork Racing Junior Sprint Heavy. Kyle Cuthbertson was third.
Paul Smith won the Clone 360 race over Desmond Lewis and Darren Greene.
Sunday Race 6
The weekend's final race saw fifteen laydown enduros take the green flag for a 45-minute contest.
Don Chrzan earned win No. 3 on the weekend in Formula 100 Final 2. Chrzan bested Adam Myers to score the hat trick. Mike Fischer was third, Travis Miller fourth and Michael Tracy fifth in the high-attrition race.
Chris Larson won his second race of the weekend and swept the Yamaha pipe laydown classes in the process. Larson won Yamaha Heavy over Brian Ellis. Dan Stowell was third, Don Johnson fourth and William Anderson fifth.
Ohio's Mallory Davis bested Fran Mazzucotelli to win 100cc Pipe Medium.
The 2013 WKA National Road Racing Series will close its season September 6-8 with the Woodbridge Kart Club-hosted Summit Point Nationals at Summit Point Motorsports Park in West Virginia. Pre-registration will be open next week.


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Printed Zip Front Leggings
Style # 232218
AVAILABILITY: Unavailable for immediate shipment.
Work it out in our New Performance Fabric! Hit the treadmill wearing our Printed Leggings featuring a zip front closure and cropped silhouette. Style with our matching tank for the perfect ensemble.
- New Performance Fabric
- 77% Nylon, 23% spandex
- Machine wash according to care label
- Made in USA
- Rise: 7" (18 cm), Inseam: 19" (48 cm), Leg opening: 10" (25 cm)
- Model is 5'10" and wears a US size S


text: Scene to Be Seen (Outer) is a subtly, warm-toned plum with a frosted, metallic sheen. It had so-so color payoff, was slightly powder, and did emphasize pores. MAC Lavish Living (LE, $25.00) is cooler-toned. theBalm Cabana Boy (P, $21.00) is less warm-toned. Chanel Plum Attraction (LE, $43.00) is darker. See comparison swatches.


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LNN Videos
2013-14 Lions International President Barry Palmer
8:59 minutes
Meet Barry Palmer, the 2013-14 Lions International President and the first ever Australian to be elected president of Lions. IP Palmer was born in Hornsby, New South Wales and met his wife, Anne, while playing drums in a rock and roll band. Watch this biographical video to learn how he is following his dream.
He seems to be a man with great integrity and honour. I am glad to have him as our new LC-President. Best wishes for "Down Under"!
– Manuela Blocher-Schimmel – Ã�hringen, Deutschland
I have to congratulate with you and encourage all Lions members to help children all over the world (from Africa to South and Central America and Malaisia and so on....)We have to interest much more about poor people and less about our personal interests. Good luck and go on following your dream!!!
– Irene loglisci – Taranto, Italy
I wish you all the luck and happy dreams.
– Alex Dirix – Sint-Truiden


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Out of Stock
Item # POL0066
Don't worry though, we have a lot more Heart Rate Monitors in stock than that.View Similar Products
Polar FT40 Heart Rate Monitor $0.00
Unlike its bulky, ugly competition, the Polar FT40 Heart Rate Monitor packs all the technical performance into a slim, stylish package. While it may look like an everyday watch, the FT40 features a wireless heart rate function with target zone alarms, real-time HR data, and a 50-exercise tracking program. Polar lets you choose between audible and visual alarms as well, so you're not beeping like mad in the gym and you don't have to stare at your watch during a trail run.
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Steve -O
Is there a difference in size between the...
Is there a difference in size between the men's (grey) and the women's (green)?
I'm thinking of getting this for my girlfriend, and like the grey/black color better and want to get that one if it's the same size as the green one..
Karen Porter
Is also for a woman? In the setup does it...
Is also for a woman? In the setup does it cater for male/female?
Rob Wykoff
Hi Karen,
The Green version is Women's Specific.
The Grey version is Men's Specific.


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Northside handed the Jones County girls their first loss of the season last Wednesday with a 3-2 victory in Warner Robins. The Lady Hounds had edged Northside by the same score earlier in the season.
The Northside boys also edged Jones County 3-2.
Coach Alisha Gordon reported that the Lady Hounds' No. 1 doubles team of Olivia Lane and Logan Bowden remain undefeated on the season, as does the Greyhounds' No. 2 singles player, Jacob Wills.
The Lady Hounds rebounded from their loss to Northside to down Houston County 3-2 at home on Thursday. The Greyhounds lost, however, falling 3-2.
Both Jones County teams blanked Putnam County 5-0 in a non-region match on Monday at home. That makes the Lady Hounds 8-1 overall and 4-1 in Region 2B-AAAAA. The Greyhounds are 5-4 overall and 1-4 in the subregion.
For the full story, pick up a copy of this week's newspaper or subscribe to our e-Edition at http://ee.jcnews.com.


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NLZ10414 In Stock
With every step, love grows. This sterling silver cz journey stencil heart pendant symbolizes how love grows stronger as two people grow together and their commitment deepens. This journey stencil heart pendant measures 3/4 inch across the widest part of the heart and is 3/4 inch in length. A sequence of graduated cubic zirconias arranged from the smallest to the largest is inset on the side of the heart- symbolizing how love intensifies and becomes more meaningful over time. What a perfect gift for that special someone! Pair this sterling silver cz journey stencil heart pendant up with our silver cz journey heart earrings and cz journey heart rings.
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I'm dying and this app is my make a wish request... ;)
App Giveaway: Farnsworth Video Communicator
Become an agent of Warehouse 13 and transform your iPhone into your very own Farnsworth with Farnsworth Video Communicator! You can send videos, audio and texts to other Farnsworth users, Facebook, and email.
If you couldn't tell from the video above, I'm having fun with this app :)
Turn your iPhone into a working Farnsworth just like the agents use on Warehouse 13!
- Send and receive videos from fellow agents that look exactly like the messages do on Warehouse 13.
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- Post messages directly to Facebook - or email them directly from your Farnsworth.
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- Get messages directly from Warehouse 13! Artie has been known to check up on new agents in the field. And you never know when you might get an assignment from Claudia. Don't be hurt if she calls you a noob. That's a term of endearment. No, really.
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Reader comments
App Giveaway: Farnsworth Video Communicator
I'm dying and this app is my make a wish request... ;)
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PS - I always loved Aaron Sorkin dialog about Philo Farnsworth on the show Sports Night...
Now this really looks like a fun thing.
I'd love a copy! yes please!
Sure, why not!
Exactly what I have been waiting for.
Living in the "Secret City" of Oak Ridge, TN, I have been a warehouse 13 agent for a while now, but never could get a Farnsworth issued to me. This is my chance. Please help me out with a copy !!!
Warehouse 13 has revived X-Files at its best. Pete and Myka are the best. The only way to emulate is with a personal Farnsworth.
is a great fan of Warehouse 13. I would love to add this to my iPhone. Thank you for your consideration. (firstname.lastname@example.com)
I want a Farnsworth
Agent Garcia reporting here!
Love WH13, this app is too funny. Would be cool if you could send video messages to anyone as a MMS. What's next, Tazer is going to releas a Tesler, LoL.
This looks awesome!
This is pretty awesome. I love Warehouse 13 and would love to become an Agent myself...
Looks like fun


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A small aurora in the sky above McMurdo Station in winter
Star trails, looking straight up over about 2 hours the movement of the stars create an overhead circular pattern. The green bits in the sky are from some auroras that passed though the shot.
The full moon about to pass behind Mount Discovery as seen from Black Island in April. This photo was taken a few days before the sun disappeared below the horizon for the winter. The sunlight only just hitting the top half of Mount Discovery.
Skidoo on the ice shelf in front of Black Island
Skidoo amongst the re-frozen melt water channels in front of Black Island
Part of the Trans-Antarctic mountains.


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I posted this on Fuse so nothing new.
My Game of the Year is BATMAN ARKHAM CITY!
What? did you think I was going to give it to anything els? Yes Skyrim was Great and the best RPG I have ever played. But EVERY OTHER CRITIC has given it GOTY, So I was a little sad, that and I just love playing Batman more than Skyrim.(and I'm a fanboy... psssst that has nothing to to with it)
Best RPG
Best Shooter
Gears of War 3. Its not MW3, not Battlefield 3, but GEARS OF WAR 3!
and best Action
Batman Arkham City!
Thats my "Best of 2011" hope you liked it. Thats all.


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I was wandering what You know about polish players or polish clubs any ideas?
I know kusack at Man utd. And I know some Polish clubs but not to much about them. And I know that Lukas Podolski is actually Polish? Is that for real?
I got a few questions to you
Who is the best Polish player ever?
Best current player?
Best up and coming youngster?
Yes, Kuszczak is Polish - played well against AS Rome. In fact Poland is lucky with goalkeepers. We have Kuszczak (Man U) and Lukasz Fabianski (Arsenal Londony) and the most impressive now Artur Boruc at Celtic Glasgow. And of course Jerzy Dudek (Liverpool FC and now at Real Madrid).
Podolski was born in Poland but his family moved to Germany so he plays there now. The same with Miroslav Klose.
Zbigniew Boniek is told to be the best polish player ever. He got a bronze medal at World Cup 1982. Then he played in AS Rome and Juventus Turyn - now he work in polish football federation. Grzegorz Lato is also famous - he was a top goalscorer at World Cup.
Currently the best polish player is Artur Boruc - Celtic Glasgow goalkeeper. In good form is also Jacek Krzynowek (VfL Wolfsburg) and Ebi Smolarek (Racing Santander).
As for youngsters I would say that Jakub Blaszczykowski is very impressive at Borussia Dortmund and Fabianski from Arsenal is very good, but as for now he is on the bench.
Heard much about Fabianski but never seen him play myself. What's his strengths? How old is he?
Yes, Boruc I have also heard about. And from what I have heard he is a success at Celtic and have been linked with lots of English premiership clubs. DO you believe it would have done him good to make the move to the premiership?
What kind of player is Blaszczykowski? What position? What age? What is his strength's? Are bot Blaszczykowski and Fabianski on the Polish Under-21 team, or?
Fabia?ski - born in 1985, so he is 22. He made a great start in Legia Warsaw (what is interesting it was after Boruc left the club for Celtic) - he played just two seasons for Legia and now he moved to Arsenal. He wasn't succesful for the any under something team but he already is very close to the first national team. He is still very young but experienced in Orange Ekstraklasa. He needs some time to get used to Premiership but I believe he can be great if not in Arsenal maybe in some less popular clubs like Fulham, Portsmouth etc.
Kuba Blaszczykowski - this is impressive carrer - he is also 22 years old. In 2004 he moved to Wisla Krakow. He spend two seasons there and at start of this season he moved to the Borussia Dortmund. He plays on the right site. He is better as a winger (midfielder) but he started as a right back. He is already one of the best players in our first national team.
Boruc is 27 - so a good age for a goalkeeper. He is perfect at Celtic. Arsenal and AC Milan are interested in getting him. Barcelona was also during the summer. But Celtic didn't let him go.
Boruc, Kuszczak and Fabianski are very good goalkeepers and I believe that they made a right choice moving to Premiership, Scotland Premier League as there are not to many good keepers.
Thanks for all the good info on the Polish players mike
I just wondered about a thing. In Russia and several other Eastern European countries they have brought in several Brazilian and South American players, is that the trend in Polish football as well?
Russian and Ukrainian clubs can afford to hire most of the smaller stars from America.
Polish clubs do hire some of the Brazilians, Nigerians etc, but they usually aren't so good. Once we had in Polonia Warsaw Emmanuel Olisadebe - he was given polish passport and played really well in national team. He moved to Panathinaikos and now I don't hear about him.
The second good player was Kalu Uche. He nows plays in Spain. But not to many foreign players do well in Poland. For those really good Poland is not an attractive direction. For those weaker - they are simply to weak


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The Ladybug Bed Tent by Pacific Play Tents encourages imaginations at any time of the day. The whimsical design of an adorable ladybug adorns the dome style construction of this bed tent providing a secure play area during the day and a relaxing and quiet sleep experience at night.
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Shipping Note: This item ships directly from the manufacturer within contiguous United States only. Cannot be shipped to AK/HI, PO boxes, US territories, or APO/FPO addresses.


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Keyboard instruments > Piano, 4-hands
Ludwig van Beethoven
Works for Piano Four-hands
Editor: Hans Schmidt
89.00 $
Complete Edition, critical report, Abteilung VII, Band 1, paperbound
Editors of the critical report: Frank Buchstein, Hans Schmidt
Pages: 59 (I, 2, 3/4, 5, 6, 7, 8, 59)
Order no. HN 4233 · ISMN M-2018-4233-2
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- Piano Sonata D major op. 6
- March C major op. 45,1
- March E flat major op. 45,2
- March D major op. 45,3
- 8 Variations on a Theme by Waldstein C major WoO 67
- 6 Variations, Song with Variations D major WoO 74
- Appendix: 6 Variations, Song with Variations, early version D major WoO 74
- Appendix: Grand Fugue transcribed by the composer op. 134


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SAN ANTONIO, Texas - The No. 4 seed New Mexico State volleyball team upset No. 1 seed Utah State in the semifinals of the 2012 Western Athletic Conference Tournament, Tuesday, Nov. 20 in San Antonio, Texas.
Sophomore Meredith Hays paced the Aggies offensively with a match-high 17 kills as the Crimson Aggies swept USU 25-21, 25-19, 25-16. This was a completely different match than the two regular-season matches as NM State did not allow a single USU player to get more than seven kills.
"We played a great match all-around," head coach Mike Jordan said. "We played great defense, passed the ball well and served the ball tough. It was a great team effort tonight."
NM State served the ball tough against USU marking nine service aces with junior Stephanie Ziegler marking a career-high three, while three other players added two each. Utah State tallied only two service aces against the southern Aggies.
Junior middle hitter Desiree Scott added 10 kills against USU while junior Preslie Alexander tallied eight kills on a .615 hitting percentage. Alexander didn't make a single error on 13 swings. NM State as a team posted 47 kills compared to only 26 kills by the UtAgs.
With the Aggies running a 6-2 offense again, junior Ciara Brown marked a match-high 27 assists and freshman Taylor Livoti posting 12. Livoti was great at the service line as she forced USU to pass the ball all over the floor, while also adding two service aces.
Scott led the Aggies in set one with four kills as NM State took a 1-0 lead winning 25-21. In a set that saw three ties and one lead change, both teams opened the match with determination to do what it takes to win. After falling behind 8-4, NM State put together a 5-1 scoring rally to tie it up at 9-9. The set was close mid-way thru with NM State taking a 15-14 lead on a kill by Hays. NM State would not lose the lead from that point with Livoti marking a service ace to seal the set.
NM State jumped out to an early 6-1 lead in set two as Hays tallied eight kills in the set leading the way to a 25-19 win. The southern Aggies went up by as many as eight at 20-12 when Hays hammered down another kill. Livoti wrapped up the set for her team for the second time in as many sets with a service ace against the UtAgs.
Hitting .323 in set three and holding USU to a .067 hitting percentage, NM State looked dominate winning 25-16. NM State marked four service aces in the set and USU posted six attack errors to boost the Crimson Aggies into the WAC Tournament Championship against No. 2 seed Idaho, Wednesday, Nov. 21 at 3 p.m. (MT).
Tomorrow's match against the Vandals is scheduled to air on ESPNU as well as on ESPN3.ccom, while it can be heard over the radio waves in Las Cruces on KSNM AM 570 with Jay Sanderson giving the play-by-play action. The winner of the title match gets an automatic bid into the NCAA Tournament with the selection show on Sunday at 2 p.m. (MT).


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The Walking Dead
The Walking Dead Season 3 Sneak Peek of Episode 9: Nope, That's Not Beth's Baby (VIDEO)
Nothing too vital happens in this domestic scene from The Walking Dead Season 3, Episode 9, "The Suicide King." Hershel patches up new prison guy Allen, and reveals to Tyreese and Sasha that he was bit. We see Beth holding the "barely a week" old baby, and the newbies are shocked since they never expected to see a baby again. Sasha thought Beth was the mother, but when she asked what happened to the mother, everyone went silent.
Question: Do you think Beth will end up in a romance with the new younger prison guy, Ben? Producer Gale Ann Hurd teased "a little love" and "a lot of betrayal" for the rest of the season. Maybe Tyreese's has a love interest (Carol? Michonne?) but it's also possible Beth gets a crush. And where is Carol in this scene?
Catch up on all kinds of Walking Dead recaps, spoilers, news, videos and polls at Wetpaint.com/the-walking-dead.


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Monday, November 14, 2005
Google Maps Beer Hunter
In Ontario, Canada liquor is not sold in grocery or corner stores. Instead it's sold by retail outlets controlled by the government. BeerHunter.ca is a Google Maps mashup that shows these outlets as well as their open and close times (closed stores are shown with 50% transparent icons). People working at the beer store may never have to answer the phone again!
(BeerHunter.ca currently only lists outlets in Toronto, but will be adding more Ontario locations soon!)
Technorati Tags: [beer], [Toronto], [Ontario], [googlemaps], [googlemapsmania]
Posted by Mike Pegg at 8:07 PM
Subscribe to: Post Comments (Atom)


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Charleston in South Carolina just happens to be the 2nd largest city in the state with a population of more than 122,000. The name of the city honors Charles Towne, the King Charles II of England. Travel companies and experts have recognized Charleston as a top city in the nation, the best mannered, sexiest, friendliest, the most polite and hospitable city and even the 2nd best dressed city in America. You will have to go to Charleston to see it for yourself.
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ground(ctrl) is now Wonderful Union
2015 brings some very exciting changes for our company. Since launching ground(ctrl) 7 years ago, our company and vision have grown into something uniquely wonderful. We have established ourselves as a unifying element between artists and fans, and this purpose has redefined us.
Moving forward, ground(ctrl) will be known as Wonderful Union. We are proud of who we are and what we do, but we have always operated behind the scenes. Wonderful Union is about all of us. It's about how we unite fans with the artists they love, and together, we are all Wonderful Union. Thank you for being with us for these first seven years, and we hope you'll be with us for many years to come.
Thank you from all of us here in Sacramento, Nashville, Tokyo and beyond!
Wonderful Union


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Mac, are you living without a power bill, off the grid?
Mac, are you living without a power bill, off the grid?
We are on (the end of) the grid. We got the power line extended over 1km. A neighbour with solarcells objekted to the extn. And the local environment group objekted, koz lots of trees hadtabe kut down or pruned (mostly on the road). This held up our permit for our house but in the end we got the ok. And then our underground connektion to the house (over 200m) kost us heaps.
We looked at solarcells. I reckon it would hav needed over $100,000 of cells and batterys.
At prezent u kan get a subsidy if u install cells, and u kan then sell power to the grid. Some folks get their power for free (make a profit even). But we karnt be bothered with that stuff. Cells would look ugly on our house. Except that u karnt see the house from the street, and only the kangaroos and koalas kan see the house from the bush behind our joint.
We hav a phone landline, but no gas, and we harvest out own roof water. Krapp goze to a septik tank and then to seepage lines. A dish on our roof for emails and www.
Lots of folk round here hav big or small windturbines too -- dunno much about turbines. Anyhow we will hav the last larff when we install our aetherik-chimney-turbine -- hahhhahahaha.
Last edited by cushioncrawler; 08-06-2013 at 08:28 PM.
I have a well and septic myself, so I hear ya. I figured if living off the grid was do-able, you would be one of the first.
We lived with my bro next door for a year and he had a 3hp motormower engine running a car-generator feed 6 old truck batterys. After watching tv for 2hrs we would havta run the engine to watch more. And the wasps kept filling the invertors with mud -- expensive. Anyhow he iz now on the grid same az us. U kan opt to pay for green power, from wind turbines, costs more (just a pr excercise i think) -- i see they are installing 64 ovem about 12km from here. And there must allready be about 640 hereabouts.
Anyhow one day someone will probly install some solarcells on the roof, feeding back into the grid (when we are gone).
I've seen resorts completely independent, but not sure of the cost. There are people up here who have done it with solar panels, an inverter, and a series of marine batteries. Not very cost efficient though. And what they give back to the grid, helps the grid much more than them. If I could only get my mother in law to pedal a bicycle, I'd be set. Throw her a few clams, and that old battle axe drill sergeant can really get going!


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Celebrity birthdays for the week of Aug. 9-15
Aug. 9: Comedian-director David Steinberg is 73. Actor Sam Elliott is 71. Singer Barbara Mason is 68. Full Story
Dr. Dre releasing first album in nearly 16 years
'Detox' is off but 'Compton: A Soundtrack,' inspired by the upcoming N.W.A. biopic 'Straight Outta Compton,' will be released on iTunes and Apple Music on Friday.