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|130 posts found
Hard Core Member
Joined: 7/18/10
Veni, Vidi, Converti
F2P is a cause for concern on eg iOS/Android app stores, not the top ranking games, but for other devs who want to develop an app for a sustainable profit, even 0.99$ is under threat. For mmorpgs, maybe it's not a bad thing, if it allows players to try more mmorpgs and stick with and spend on the ones that are good? Perhaps players will become innoculated to the nickel and dime approaches and "good forms" of F2P might develop/become more standard?
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Advanced Member
Joined: 2/15/05
The author sounds like those who used to say "video tapes will kill movie industry". Let go and embrace the future, f2p is how games will survive. Without it game would suck even more then they suck now. I for sure don't want to live in world of WOW any more. Bring on f2p, bring on huge selection and let me have a choice.
No fate but what we make, so make me a ham sandwich please.
Novice Member
Joined: 9/27/08
The F2P business model isn't a bad concept. I personally think it's a great one. The problems I see with the model are the P2W (which is thrown around way too much) and developers not caring enough about their players to make a quality product. Sure some companies have used it to save a dieing game, for the most part to great success. If the game doesn't hamper you from questing and leveling (LORTO is a great example of hampering the questing) that make the game more enjoyable. Quest packs shouldn't be sold on a cash shop. The entire game should be available for everyone to play. Love or hate the game, Star Trek Online is a great example of how F2P should be run. The entire game is there for EVERYONE to enjoy. But if you want more out of it, buying new ships with cash is nice. This business model also allows players that normally can't afford an MMO to casually play. I know some people feel that if someone can't afford to play a game they shouldn't be able to, but there are circumstances that make a sub not an option, such as having kids, going to school, and seasonal work. It also helps friends play together. Some can afford the extra sub and their friends can't, but they can all enjoy a F2P game. Do some companies do F2P specifically because they are greedy? Sure. But if people enjoy their games and are happy with the services or virtual goods they provide, then what does it matter. If you don't agree with the model then just don't support it.
Spotlight Poster
Joined: 2/06/09
Some have swallowed the3 Arenanet "guide to promoting our MMO" handbook and then post it on here verbatim as if they are experts on the matter.
This doom and gloom thread was brought to you by Chin Up™ the new ultra high caffeine soft drink for gamers who just need that boost of happiness after a long forum session.
Novice Member
Joined: 6/30/12
F2P isn't killing the gaming industry, the industry itself and the greed with cost of games and subscriptions is killing the gaming industry. If I can find a free to play game that is just as well developed and as fun to play as one that costs, I'll play the free one.
Perhaps if they weren't so damn greedy and charge you 60 dollars and up for the game then a subscription each week people wouldn't be looking to another avenue to play games. Gamers love to play, I love to play, however, I don't see why I should pay so much money in order to play.
The article/OP was an excellent run-down of the history leading from the inception of MMOs to the current F2P environment, and I'm grateful for Derek's work on this. He brought an excellent point, with a forthcoming conclusion I immediately see as potentially misguided; the point made was about developers coming up with new ways to counter people taking advantage where they should not do so.
The conclusion is that the problem is not in the developers, it's in the people, in the communities. Here are my ideas of how to fix it.
A LOT of problems have arisen from the various communities, complainers, twitchers, about developers not doing this or not doing that, not developing all they said they would do, and much scorn can also be derived from multiple various articles and tutorials on this site, as well. If players don't get what they want, or get what they said they were going to get, many turn into stark-raving lunatics, bash the developers -bash being a very light term for what these monkey's do- and bash the game. This is true for in-game items, general requests for content, artwork, etc., and it's sad, because the community is responsible for not only the downfall of their own favorite or desired game, but for all of massively multiplayer gaming.
So, at the risk of sounding like I'm simply adding another step in the MMO development process, another means of staving off the miscreants who work so very hard to destroy the game through their lack of consideration for others, I offer the following:
Developers should go into a game, not have to change course necessarily in the middle of development, with the understanding they are only the first-half of the life of the game. The second-half is the community and they need to plan for them. How do they accomplish that?
A LOT of what's been stolen from developers has to do with content, whether it's adventures, gear, abilities, clothing, etc. Unfortunately, simultaneously, a lot of what's been ignored by developers is the ability of players to develop their own content for sale. It would take effort on the developer's part, post-game launch, to monitor content loaded into a server separate of the game servers, which holds the development tools, to review and ensure that content is viable and useful for the game, and to ensure 3rd party developers are not trying to charge an arm and a leg for that content. However, once the content is up in the cash shop -and make the shops a PART of the game, not an extra web page or a separate app or utility altogether, but part of the immersion of the game, if possible-, allow the 3PD to have 2/3rds of all "cash" sales, and the other 1/3rd goes to the developer.
If there are, truly, that many people who want to develop in-game goods, and there are that many people who want to purchase it, and the developers are willing to provide the development tools, then why not allow that to take place? It would be a win-win-win for everyone, giving the 1P developers, more or less, free income, the 3P developers a means of supplementing real income at home, and to build wealth and notoriety in the game, customers a large outlet for their non-gifted expressions, and would help cut back, at least, on the theft of those who would ruin the game, and bring MMORPGs to the ground solely for their real-world benefit.
I can't be the only one thinking this, guys.
Novice Member
Joined: 12/01/10
I think that the genre is going to crap because players just want to blow through the game, and Dev teams allow this. What happened to taking months or longer to get to the end game? And there is no risk vs reward in games anymore. Eve being an exception. Mmo's have been so dumbed down and tamed by the mass amount of people who just want to reach max level max gear at any cost. Not enjoying the trip along the way at all. It's not f2p or b2p that is ruining the genre, its the crap games that keep being released over and over again.
I absolutely 100% agree with you. What we need is a return to Oblivion-style gaming, where there's a main quest, a meta-plot to move forward, and then several hundred side-tasks and full quests -real quests, not fetch me 10 bear skins and return- that allow for a sense of accomplishment, as it takes so much to get there, and takes more than the big three to do it, it actually requires some brain power and real cooperation between folks, not "You're the tank, I'm the healer, we need a...".
I had read somewhere, and I was coming to believe, that MMO developers were intent on re-introducing stories into MMOs, similar to those in Secret World, but all I read about, anymore, is how quickly folks do blow through the game. It's sad.
Novice Member
Joined: 9/20/10
"Get the poison out!"
Originally posted by erictlewis
That is the answer! It's obvious for people who have common sense. Unfortunately, the editor who wrote this article has no clue what he is talking about. Trying to say that F2P started because of piracy is the biggest joke and so false.
Yak Cast | MMO Podcast: http://www.yak.mmoSmackTalk.com
Aion Correspondent
Joined: 8/07/09
Let's be honest here, this article is not complaining about free to play. While yes, free to play does have DLC, cash shops, and all that, buy/pay to play also have all that too and can often be just as bad about it. So really, the arguement here should be "DLC and micro-transactions are killing gaming", not F2P. And those are two things that are a problem independent of the payment model of any given game.
Novice Member
Joined: 9/22/11
Originally posted by TwiPhoenix
Good points, TwiPhoenix; well-done.
Hard Core Member
Joined: 12/17/10
While some sub games do have cash shops they are not nearly as bad as the f2p games. Those really abuse it. In fact they make it almost impossible to play without purchasing stuff. That is the problem not so much cash shops as such but cash shops that become compulsory purchases to advance.
Apprentice Member
Joined: 1/24/11
My personal preference against RMT and Cash Shops is merely that I play to relax and a big part of relaxing means not having to reach for my wallet or think about if my game is complete or not.
That aside the main objection I have to the F2P/Cash Shop/RMT dynamic in MMO's is that it by it's very nature forces devs to focus development on how to get me into the shop rather, how to make me want to spend money, rather than how to keep me interested enough in the gameplay in keep subbed. And of course the way to get me into the shop, the way to make me want to buy stuff, generally means frustrating the player, keeping things just out of reach, creating a stark contrast between working hard for a reward (if possible) and getting it easily for money. This also negatively impacts the community because why should devs let players do things for each other when those things can be sold by the devs to the players.
I can see how that would be ok for other genre's of video games, but it's antithetical to a genre that is supposed to be a persistant shared world in which a community forms.
Novice Member
Joined: 8/20/11
Regarding mmo in general, why the hell does every new sub mmo being release think they are worth $15 a month.. Why not other lower price point..
Novice Member
Joined: 9/22/11
Originally posted by kitarad
True. For most games anyway, but I am after my breaking point for cash shops. I won't tolerate even vanity cash shop / gold selling / rmah.
Advanced Member
Joined: 6/27/12
Originally posted by megabuu
STO wasn't created as F2P. Look at Perfect World if you want to talk about F2P. There is a big difference in quality between games that were a sub and went F2P and ones that were F2P to begin with. There is a reason why no one talks about Jade Dynasty, PWI and Forsaken World.
Novice Member
Joined: 3/31/08
What today's so called "gamers" fail to realize is in MMO's, free is never free. Yes, you'll get the basics as will everyone else but unless you want to lag behind other players then you've no choice but to pay for the items the game will sell like gear, mounts and much more to keep up with them.
Novice Member
Joined: 5/10/11
In 1992 the biggest browser in the world was Netscape, which cost money to purchase. Netscape often came with Internet service as a part of a bundle.
In 1995 Internet Explorer was released as part of a Windows 95 startup package. A few months later it was free.
By Netscape represented less than 1% of the entire browser market share.
Website: http://www.thegameguru.me / YouTube: http://www.youtube.com/users/thetroublmaker
Novice Member
Joined: 5/20/10
Eh hem... video games will pull in $74 billion this year alone and are projected to rake in a staggering $115 billion a year by 2015.
NOTHING is killing gaming, simply put. lol
But seriously though am i the only one who sees it the other way around? How many sub mmo's would have gone the way of the dinosaur if it didn't go to f2p model... only problem is too many damn sub-par f2p games are out/comming out, but hey, let them keep makiing them, it's not charging me anything to play.

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Jay Holmes knew Chad Ferris before last fall, but when they met at a Citadel tailgate party in November, Holmes had an agenda.
A 1989 graduate of the military college who then spent 15 years in the cotton industry, Holmes had a 21st-century textile idea: using recycled carbon fiber for marine applications.
But he needed some help finding customers, boat builders, and that's where Ferris, a local fishing captain who graduated in 1995, came in.
It turned out Ferris knew just the guy, Mark Castlow of Dragonfly Boatworks in Vero Beach, Fla., and they struck a deal.
On Tuesday morning, the trio gathered at the Isle of Palms Marina to unveil the product of their collaboration: a 15-foot black boat hull they touted as the first ever made of recycled carbon fiber.
"Looks like our dreams are kind of coming to fruition here," said Ferris, who, like Holmes, was wearing a blue checked shirt and sunglasses.
Holmes, 46, said the idea occurred to him after working at a mill in Gastonia, N.C., and then studying textile supply chains around the world.
Using his money and the proceeds of a second mortgage on his Mount Pleasant home, he founded Greentex Solutions, which takes scrap carbon and turns it into usable fabric, like the soft black oxidized polyacrylonitrile fiber, or OPF, that made up the middle layer of the hull on display Tuesday.
Castlow said he initially thought Holmes' idea was "pretty crazy" but came to believe in its feasibility as well as appreciate its environmental benefits.
He said the Greentex-supplied hull took less time and less work than the similar boat sitting next to it Tuesday and could be more than 20 percent lighter.
"Your mind starts to spin when you think of the applications for it," Castlow said, naming covers for marine pumps and structural support for houses as examples. Holmes also hopes to sell an OPF foamboard as a replacement for marine plywood.
Ferris, 39, is one of Greentex's two salesmen, and another Citadel classmate is Greentex's chief financial officer and general counsel.
Holmes has outsourced most of the work so far, to places like the United Kingdom and China, and he said some of his suppliers turned out for Tuesday's unveiling. But he aims to do all the recycling work locally, possibly as soon as this year in a building on the old Navy base in North Charleston.
"My goal for the last 20 years has always been to build a textile company in Charleston, where textiles began," Holmes said. "Bring it full circle."
Mark Castlow of Dragonfly Boatworks explains to onlookers at the Isle of Palms Marina how his boat made out of recycled carbon fiber can be more than 20 percent lighter than a similar boat that was sitting nearby.×
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|BALB/c mice are particularly well known for the production of plasmacytoma on injection with mineral oil, forming the basis for the production of monoclonal antibodies. Mammary tumor incidence is normally low, but infection with mammary tumor virus by fostering to MMTV+ C3H mice dramatically increases tumor number and age of onset. BALB/c mice develop other cancers later in life, including reticular neoplasm, primary lung tumors, and renal tumors. BALB/cByJ was separated from the BALB/cJ strain in 1935. BALB/cByJ mice have the advantage of better reproductive performance and less aggression than the BALB/cJ substrain. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in the BALB/cByJ substrain. BALB/cByJ has a deletion in the Qa2 subregion of the murine MHC. A deficiency of Acads (acyl-Coenzyme A dehydrogenase, short chain) leads to severe organic aciduria. BALB/cByJ develop a fatty liver upon fasting or dietary fat challenge and become hypoglycemic after an 18-hour fast.
Type Inbred Strain; Additional information on Inbred Strains. Visit our online Nomenclature tutorial. Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Breeding Considerations This strain is a good breeder. Species laboratory mouse H2 Haplotype d Generation F241pF246 (14-AUG-14)
Generation Definitions
View larger image
Related Genotype: A/A Tyrp1b/Tyrp1b Tyrc/Tyrc
Important Note
This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
BALB/c mice are particularly well known for the production of plasmacytomas following injection with mineral oil, forming the basis for the production of monoclonal antibodies. Although not all BALB/c substrains have been examined for plasmacytoma induction, substrains derived from the Andervont (An) lineage (which includes BALB/cByJ) typically are susceptible, while those descended from BALB/cJ are resistant (see: Potter M, 1985). Mammary tumor incidence is normally low, but infection with mammary tumor virus by fostering to MMTV+ C3H mice dramatically increases tumor number and age of onset. BALB/c mice develop other cancers later in life including reticular neoplasms, primary lung tumors, and renal tumors. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in both BALB/cJ and BALB/cByJ substrains. BALB/cByJ has a deletion in the Qa2 subregion of the murine MHC.
BALB Strains
000650 BALB/cBy 001905 BALB/cGaJ 000921 BALB/cGrRkJ 000651 BALB/cJ 001311 BALB/cWtEiJView BALB Strains (5 strains)Strains carrying Ahrb-2 allele
000645 A/HeJ 000646 A/J 000130 B6.C-H17c/(HW14)ByJ 000370 B6.C-H38c/(HW119)ByJ 000653 BUB/BnJ 000659 C3H/HeJ 000656 CBA/J 000657 CE/J 000352 CXB2/ByJ 000353 CXB3/ByJ 000354 CXB4/ByJ 000355 CXB5/ByJ 000357 CXB7/ByJ 000673 HRS/J 000679 P/J 000930 PERA/EiJ 000644 SEA/GnJ 000280 SF/CamEiJView Strains carrying Ahrb-2 (18 strains)Strains carrying Cdh23ahl allele
001137 129P1/ReJ 000690 129P3/J 000691 129X1/SvJ 000646 A/J 000647 A/WySnJ 003070 ALR/LtJ 003072 ALS/LtJ 004502 B6;AKR-Lxl2/GrsrJ 000653 BUB/BnJ 005494 C3.129S1(B6)-Grm1rcw/J 000664 C57BL/6J 004764 C57BL/6J-Cdh23v-8J/J 003129 C57BL/6J-Epha4rb-2J/GrsrJ 004820 C57BL/6J-Kcne12J/J 004703 C57BL/6J-Kcnq2Nmf134/J 004811 C57BL/6J-nmf110/J 004812 C57BL/6J-nmf111/J 004747 C57BL/6J-nmf118/J 004656 C57BL/6J-nmf88/J 004391 C57BL/6J-Chr 13A/J/NaJ 004385 C57BL/6J-Chr 7A/J/NaJ 000662 C57BLKS/J 000667 C57BR/cdJ 000668 C57L/J 000669 C58/J 010614 CBACa.B6-Cdh23ahl/Kjn 000657 CE/J 000670 DBA/1J 001140 DBA/1LacJ 000671 DBA/2J 007048 DBA/2J-Gpnmb+/SjJ 002106 KK/HlJ 000675 LG/J 000676 LP/J 000677 MA/MyJ 001976 NOD/ShiLtJ 002050 NOR/LtJ 000679 P/J 002747 SENCARB/PtJ 002335 SKH2/J 003392 STOCK Crb1rd8/JView Strains carrying Cdh23ahl (41 strains)Strains carrying Hld allele
000651 BALB/cJ 000351 CXB1/ByJ 000353 CXB3/ByJ 000354 CXB4/ByJ 000355 CXB5/ByJ 000357 CXB7/ByJView Strains carrying Hld (6 strains)Strains carrying other alleles of Ahr
000690 129P3/J 000648 AKR/J 002920 B6(D2N).Spretus-Ahrb-3/J 002831 B6.129-Ahrtm1Bra/J 000136 B6.C-H34c/(HW22)ByJ 008599 B6.Cg-Del(9Cyp1a2-Cyp1a1)1Dwn Ahrd Tg(CYP1A1,CYP1A2)1Dwn/DwnJ 002921 B6.D2N-Ahrd/J 002727 B6;129-Ahrtm1Bra/J 000652 BDP/J 000663 C57BL/6By 001139 C57BL/6ByJ 000664 C57BL/6J 000662 C57BLKS/J 000667 C57BR/cdJ 000668 C57L/J 000669 C58/J 000926 CAROLI/EiJ 000928 CAST/EiJ 000351 CXB1/ByJ 000356 CXB6/ByJ 002937 D2.B6-Ahrb-1/J 000671 DBA/2J 000674 I/LnJ 000675 LG/J 000676 LP/J 000677 MA/MyJ 000550 MOLF/EiJ 000684 NZB/BlNJ 000726 RBF/DnJ 000682 RF/J 000686 SJL/J 001146 SPRET/EiJ 000688 ST/bJ 006203 STOCK Ahrtm3.1Bra/J 000689 SWR/J 000693 WC/ReJ KitlSl/J 000933 YBR/EiJView Strains carrying other alleles of Ahr (37 strains)Strains carrying other alleles of Cdh23
002552 B6(V)-Cdh23v-2J/J 002756 B6.CAST-Cdh23Ahl+/Kjn 010615 B6.CBACa-Cdh23CBA/CaJ/Kjn 002432 B6J x B6.C-H2-Kbm1/ByJ-Cdh23v-J/J 004764 C57BL/6J-Cdh23v-8J/J 004819 C57BL/6J-Cdh23v-9J/J 005016 CByJ;B6-Cdh23v-10J/J 000275 V/LeJView Strains carrying other alleles of Cdh23 (8 strains)Strains carrying other alleles of Mdmg1
000360 B6.C-H2d Mdmg1BALB/cBy/aByJView Strains carrying other alleles of Mdmg1 (1 strain)
JAX® NOTES, April 1988; 433. H-2 Haplotypes of Mice from Jackson Laboratory Production Colonies.
JAX® NOTES, Fall 1990; 443. A Brief History of the Two Substrains of BALB/c, BALB/cJ, and BALB/cByJ Available from Animal Resources.
JAX® NOTES, Fall 1990; 443. Ulcerative Blepharitis and Periorbital Abscesses in BALB/cJ and BALB/cByJ Mice.
JAX® NOTES, July 1987; 430. BALB/cJ vs. BALB/cByJ.
JAX® NOTES, Spring 2003; 489. Malocclusion in the Laboratory Mouse.
JAX® NOTES, Summer 1992; 450. Myoepitheliomas in Inbred Laboratory Mice.
JAX® NOTES, Summer 2003; 490. Hydrocephalus in Laboratory Mice.
JAX® NOTES, Winter 2006; 504. JAX® Mice: the Gold Standard Just Got Better.
Mouse Phenome Database / SNP Facility
View Phenotypic DataPhenotypic DataBody Weight Information - JAX® Mice Strain BALB/cByJ (001026)Mouse Phenome Database
(This chart reflects the typical correlation between body weight and age for mice maintained in production colonies at The Jackson Laboratory.)
Festing Inbred Strain Characteristics: BALB/c
JAX® Physiological Data Summary [pdf]
JAX® Physiological Data Protocol [pdf]
View Related Disease (OMIM) TermsRelated Disease (OMIM) Terms provided by MGI
- Model with phenotypic similarity to human disease where etiologies involve orthologs. Human genes are associated with this disease. Orthologs of those genes appear in the mouse genotype(s).Acyl-Coa Dehydrogenase, Short-Chain, Deficiency Of; ACADSD
- Potential model based on gene homology relationships. Phenotypic similarity to the human disease has not been tested.Deafness, Autosomal Recessive 12; DFNB12 (CDH23)
Usher Syndrome, Type ID; USH1D (CDH23)
View Mammalian Phenotype TermsMammalian Phenotype Terms provided by MGIassigned by genotype
- behavior/neurological phenotype
- abnormal food preference
- given a choice, selection of a fat/protein diet declines with time (MGI Ref ID J:87779)
- abnormal liquid preference
- did not develop a preference for drinking water containing a corn oil emulsion (MGI Ref ID J:87779)
- homeostasis/metabolism phenotype
- abnormal adaptive thermogenesis
- body temperature in most BALB/cByJ mice dropped 10 degrees C in less than 4 h at 4 degrees C, with none able to maintain body temperature for longer than 8 h in the cold (MGI Ref ID J:50729)
- abnormal circulating amino acid level
- serum glycine concentrations are markedly lower than controls (MGI Ref ID J:14707)
- decreased circulating carnitine level
- slightly lower plasma carnitine level (MGI Ref ID J:14707)
- abnormal fatty acid oxidation
- block in short-chain fatty acid oxidation shown by reduced butyryl-CoA dehydrogenation in liver mitochondria (MGI Ref ID J:14707)
- aciduria
- organic aciduria at 7-14 weeks of age, caused by relatively large amounts of n-butyrylglycine and ethylmalonate in the urine (MGI Ref ID J:9743)
- ethylmalonate, methylsuccinate, and butyrylglycine urinary excretion is higher than in controls (MGI Ref ID J:4165)
- markedly increased urinary concentrations of ethylmalonic and methylsuccinic acids, and N-butyrylglycine in nonfasting and fasting mice, and remained elevated with or without medium chain triglyceride challenge (MGI Ref ID J:14707)
- upon dosing with carnitine, mice excrete large amounts of butyryl-carnitine in the urine (MGI Ref ID J:14707)
- hypoglycemia
- hypoglycemia develops after 18 hours of fasting with mean serum glucose measuring less than half of control values (MGI Ref ID J:14707)
- increased circulating HDL cholesterol level
- HDL levels were significantly increased in mutant mice for both males and females fed either a regular chow or a high-fat diet (MGI Ref ID J:164460)
- liver/biliary system phenotype
- hepatic steatosis
- fat deposits accumulate in the liver after 18 hours of fasting or with dietary fat challenge (MGI Ref ID J:14707)
- renal/urinary system phenotype
- aciduria
- organic aciduria at 7-14 weeks of age, caused by relatively large amounts of n-butyrylglycine and ethylmalonate in the urine (MGI Ref ID J:9743)
- ethylmalonate, methylsuccinate, and butyrylglycine urinary excretion is higher than in controls (MGI Ref ID J:4165)
- markedly increased urinary concentrations of ethylmalonic and methylsuccinic acids, and N-butyrylglycine in nonfasting and fasting mice, and remained elevated with or without medium chain triglyceride challenge (MGI Ref ID J:14707)
- upon dosing with carnitine, mice excrete large amounts of butyryl-carnitine in the urine (MGI Ref ID J:14707)
- cellular phenotype
- abnormal fatty acid oxidation
- block in short-chain fatty acid oxidation shown by reduced butyryl-CoA dehydrogenation in liver mitochondria (MGI Ref ID J:14707)
- muscle phenotype
- abnormal skeletal muscle morphology
- wehn dosed with carnitine, mutant muscle exhibits a 9-fold increase in butyryl-carnitine concentration compared to controls (MGI Ref ID J:14707)
Hld/Hldeither: BALB/cByJ or BALB/cJ
- nervous system phenotype
- abnormal dendrite morphology
- abnormal hippocampus morphology (MGI Ref ID J:13989)
- abnormal hippocampal mossy fiber morphology (MGI Ref ID J:12029)
- abnormal hippocampus CA3 region morphology
- there is abnormal lamination of this cell layer resulting in superficial early generated neurons and deep late-generated neurons (MGI Ref ID J:12029)
- abnormal hippocampus layer morphology
- ectopic hippocampus pyramidal cells
- located below the intrapyramidal layer; some of the ectopic cells have short, fine-caliber dendritic branches arising near the points of contact of the intrapyramidal mossy fibers (MGI Ref ID J:12029)
- abnormal neuronal migration (MGI Ref ID J:13989)
- cellular phenotype
- abnormal neuronal migration (MGI Ref ID J:13989)
View Research ApplicationsResearch ApplicationsThis mouse can be used to support research in many areas including:
Cdh23ahl related
Cancer Research
Increased Tumor Incidence
Mammary Gland Tumors
Mammary Gland Tumors: late onset
Immunology, Inflammation and Autoimmunity Research
experimental allergic encephalomyelitis (EAE)
Neurobiology Research
Hearing Defects
Age related hearing loss
Neurodevelopmental Defects
callosal agenesis, incomplete penetrance
Research Tools
Cancer Research
monoclonal antibodies, myeloma and hybridoma production
General Purpose
Immunology, Inflammation and Autoimmunity Research
background strain for histocompatibility congenics
Sensorineural Research
Hearing Defects
Age related hearing loss
Neurobiology Research
Hearing Defects
Age related hearing loss
Sensorineural Research
Hearing Defects
Age related hearing loss
|Allele Symbol
|Allele Name
|deletion, Jackson
|Allele Type
|Common Name(s)
|Bcd-1c; Scad;
|Strain of Origin
|Gene Symbol and Name
|Acads, acyl-Coenzyme A dehydrogenase, short chain
|Gene Common Name(s)
|ACAD3; AI196007; Bcd-1; Bcd1; HDL QTL 8; Hdlq8; SCAD; butyryl CoA dehydrogenase 1; expressed sequence AI196007;
|Molecular Note
|A 278bp deletion occurs which starts in intron "A" and includes exon "B" and the first 78bp of exon "C". As a result of this deletion, mRNA transcription is reduced to about 35% of normal and includes two forms, a longer normal length transcript and a shorter misspliced form. If these mRNAs were translated they both would result in truncated products. Protein product is undetectable immunologically and there is a total absence of enzyme activity. [MGI Ref ID J:12776] [MGI Ref ID J:50729]
|Allele Symbol
|Allele Name
|b-2 variant
|Allele Type
|Not Applicable
|Common Name(s)
|Ahb-2; Ahh;
|Strain of Origin
|Gene Symbol and Name
|Ahr, aryl-hydrocarbon receptor
|Gene Common Name(s)
|Ah; Ahh; Ahre; In; aromatic hydrocarbon responsiveness; aryl hydrocarbon hydroxylase; bHLHe76; dioxin receptor; inflammatory reactivity;
|General Note
C57BL/6 carries the responsive Ahrb allele; DBA/2 carries nonresponsive Ahrd. Heterozygotes (Ahrb/Ahrd) are responsive (J:5282). Later work identified a second (J:8895) and later a third (J:22144) allele conferring response. Thus the allele in C57, C58, and MA/My strains is now Ahrb-1; Ahrb-2 is carried by BALB/cBy, A, and C3H; and Ahrb-3 by Mus spretus, M. caroli, and MOLF/Ei. The nonresponsive strains AKR, DBA/2, and 129 carry Ahrd (J:22144). Nucleotide and amino acid sequence differences between Ahrb-1 and Ahrd have been determined (J:17460).
Strain of origin - this allele was found in BALB/cByJ, A/J, C3H/HeJ, CBA strains
|Molecular Note
|This allele encodes a high affinity, heat labile, 104 kDa receptor containing 848 amino acids. Sequencing studies of cDNA from C57BL/6J congenic mice homozygous for this allele identified nucleotide substitutions in the ORF that would cause 5 amino acid differences between the C57BL/6J and BALB/cBy peptides, and 2 amino acid differences between the BALB/cBy and DBA/2J peptides. A T to C transition in exon 11 replaces the opal termination codon in the C57BL/6J allele with an arginine codon in the BALB/cByallele. This change would extend translation of the BALB/cBy mRNA by 43 amino acids, accounting for the larger size of the peptide produced by this allele (104 kDa, vs 95 kDa for the C57BL/6J allele). [MGI Ref ID J:15153] [MGI Ref ID J:22144]
|Allele Symbol
|Allele Name
|age related hearing loss 1
|Allele Type
|Common Name(s)
|Cdh23753A; mdfw;
|Strain of Origin
|multiple strains
|Gene Symbol and Name
|Cdh23, cadherin 23 (otocadherin)
|Gene Common Name(s)
|4930542A03Rik; CDHR23; RIKEN cDNA 4930542A03 gene; USH1D; W; age related hearing loss 1; ahl; bob; bobby; bus; bustling; mdfw; modifier of deaf waddler; neuroscience mutagenesis facility, 112; neuroscience mutagenesis facility, 181; neuroscience mutagenesis facility, 252; nmf112; nmf181; nmf252; sals; salsa; v; waltzer;
|Molecular Note
|Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further analysis has identified an association between ahl and a G to A transition at nucleotide position 753 of Cdh23. This hypomorphic allele causes in frame skipping of exon 7 and reduced message stability. Twenty-seven strains classified with ahl and carrying the 753A allele include: CD1, RBF/DnJ, PL/J, AKR/J, RF/J, BALB/cBy, A/WySnJ, P/J, SENCARA/PtJ, DBA/1J, ALS/LtJ, C58/J, C57BLKS/J, 129P1/ReJ, C57BR/cd, SKH2/J, BUB/Bn, MA/MyJ, LP/J, 129X1/SvJ, NOR/LtJ, A/J, C57BL/6, NOD/LtJ, DBA/2J, ALR/LtJ, C57L/J. Strains classified with ahl that DO NOT carry this mutation include: C3H/HeSnJ, I/LnJ,YBR/Ei, MRL/MpJ. [MGI Ref ID J:86905]
|Allele Symbol
|Allele Name
|hippocampal lamination defect
|Allele Type
|Strain of Origin
|Gene Symbol and Name
|Hld, hippocampal lamination defect
|Gene Symbol and Name
|Mdmg1, mandibular morphogenesis 1
|Gene Common Name(s)
Inbred mouse strains are maintained through sibling (sister x brother) matings; no genotyping required.
Genotyping resources and troubleshooting
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Hinsdale ME; Kelly CL; Wood PA. 1993. Null allele at Bcd-1 locus in BALB/cByJ mice is due to a deletion in the short-chain acyl-CoA dehydrogenase gene and results in missplicing of mRNA. Genomics 16(3):605-11. [PubMed: 8325633] [MGI Ref ID J:12776]
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Smith Richards BK; Belton BN; York B; Volaufova J. 2004. Mice bearing Acads mutation display altered postingestive but not 5-s orosensory response to dietary fat. Am J Physiol Regul Integr Comp Physiol 286(2):R311-9. [PubMed: 14592933] [MGI Ref ID J:87779]
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International Nomenclature Committee. 1952. COMMITTEE on Standardized Nomenclature for Inbred Strains of Mice Cancer Res 12(8):602-13. [PubMed: 14945054] [MGI Ref ID J:166288]
Moy SS; Nadler JJ; Young NB; Perez A; Holloway LP; Barbaro RP; Barbaro JR; Wilson LM; Threadgill DW; Lauder JM; Magnuson TR; Crawley JN. 2007. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res 176(1):4-20. [PubMed: 16971002] [MGI Ref ID J:138682]
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Smith BK; Andrews PK; West DB. 2000. Macronutrient diet selection in thirteen mouse strains. Am J Physiol Regul Integr Comp Physiol 278(4):R797-805. [PubMed: 10749765] [MGI Ref ID J:61602]
Southwick CH; Clark LH. 1966. Agressive behavior and exploratory activity in fourteen mouse strains Am Zool 6:559. [MGI Ref ID J:23455]
Teuscher C; Blankenhorn EP; Hickey WF. 1987. Differential susceptibility to actively induced experimental allergic encephalomyelitis and experimental allergic orchitis among BALB/c substrains. Cell Immunol 110(2):294-304. [PubMed: 2446778] [MGI Ref ID J:149656]Acadsdel-J relatedAhrb-2 related
Amendt BA; Freneaux E; Reece C; Wood PA; Rhead WJ. 1992. Short-chain acyl-coenzyme A dehydrogenase activity, antigen, and biosynthesis are absent in the BALB/cByJ mouse. Pediatr Res 31(6):552-6. [PubMed: 1635815] [MGI Ref ID J:1360]
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Guerra C; Koza RA; Walsh K; Kurtz DM; Wood PA; Kozak LP. 1998. Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation. J Clin Invest 102(9):1724-31. [PubMed: 9802886] [MGI Ref ID J:50729]
Kruger C; Kumar KG; Mynatt RL; Volaufova J; Richards BK. 2012. Brain transcriptional responses to high-fat diet in Acads-deficient mice reveal energy sensing pathways. PLoS One 7(8):e41709. [PubMed: 22936979] [MGI Ref ID J:191682]
Prochazka M; Leiter E. 1985. A null activity variant found at the butyryl CoA dehydrogenase (Bcd-1) locus in BALB/cByJ subline. Mouse News Lett 75:31. [MGI Ref ID J:14101]
Qureshi IA; Leblanc D; Cyr D; Giguere R; Mitchell G. 1993. Breeding experiments to combine the X-linked sparse-fur (spf) mutation with the autosomal recessive BALB/cByJ strain: testing the biochemical phenotype of double-mutant mice as a model for ammonia: fatty acyl CoA synergism. Biochem Biophys Res Commun 191(2):744-9. [PubMed: 8461026] [MGI Ref ID J:4165]
Reue K; Cohen RD. 1996. Acads gene deletion in BALB/cByJ mouse strain occurred after 1981 and is not present in BALB/cByJ-fld mutant mice. Mamm Genome 7(9):694-5. [PubMed: 8703125] [MGI Ref ID J:35550]
Schiffer SP; Prochazka M; Jezyk PF; Roderick TH; Yudkoff M; Patterson DF. 1989. Organic aciduria and butyryl CoA dehydrogenase deficiency in BALB/cByJ mice. Biochem Genet 27(1-2):47-58. [PubMed: 2712823] [MGI Ref ID J:9743]
Schuler AM; Gower BA; Matern D; Rinaldo P; Vockley J; Wood PA. 2005. Synergistic heterozygosity in mice with inherited enzyme deficiencies of mitochondrial fatty acid beta-oxidation. Mol Genet Metab 85(1):7-11. [PubMed: 15862275] [MGI Ref ID J:98027]
Schuler AM; Gower BA; Matern D; Rinaldo P; Wood PA. 2004. Influence of dietary fatty acid chain-length on metabolic tolerance in mouse models of inherited defects in mitochondrial fatty acid beta-oxidation. Mol Genet Metab 83(4):322-9. [PubMed: 15589119] [MGI Ref ID J:94661]
Skilling H; Coen PM; Fairfull L; Ferrell RE; Goodpaster BH; Vockley J; Goetzman ES. 2010. Brown adipose tissue function in short-chain acyl-CoA dehydrogenase deficient mice. Biochem Biophys Res Commun 400(3):318-22. [PubMed: 20727852] [MGI Ref ID J:165594]
Su Z; Leduc MS; Korstanje R; Paigen B. 2010. Untangling HDL quantitative trait loci on mouse chromosome 5 and identifying Scarb1 and Acads as the underlying genes. J Lipid Res 51(9):2706-13. [PubMed: 20562441] [MGI Ref ID J:164460]
Wang W; Mohsen AW; Uechi G; Schreiber E; Balasubramani M; Day B; Michael Barmada M; Vockley J. 2014. Complex changes in the liver mitochondrial proteome of short chain acyl-CoA dehydrogenase deficient mice. Mol Genet Metab 112(1):30-9. [PubMed: 24685553] [MGI Ref ID J:212122]
Wood PA; Kelly-Kurtz CL; Hinsdale ME; Hamm DA; Rhead WJ. 1999. Lessons learned from the mouse model of short-chain acyl-CoA dehydrogenase deficiency Adv Exp Med Biol 466:395-402. [PubMed: 10709668] [MGI Ref ID J:61299]Cdh23ahl related
Nebert DW; Considine N; Owens IS. 1973. Genetic expression of aryl hydrocarbon hydroxylase induction. VI. Control of other aromatic hydrocarbon-inducible mono-oxygenase activities at or near the same genetic locus. Arch Biochem Biophys 157(1):148-59. [PubMed: 4716952] [MGI Ref ID J:84313]
Nebert DW; Gielen JE. 1972. Genetic regulation of aryl hydrocarbon hydroxylase induction in the mouse. Fed Proc 31(4):1315-25. [PubMed: 4114109] [MGI Ref ID J:5282]
Nebert DW; Jensen NM; Shinozuka H; Kunz HW; Gill TJ 3rd. 1982. The Ah phenotype. Survey of forty-eight rat strains and twenty inbred mouse strains. Genetics 100(1):79-87. [PubMed: 7095422] [MGI Ref ID J:6809]
Nebert DW; Robinson JR; Niwa A; Kumaki K; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. J Cell Physiol 85(2 Pt 2 Suppl 1):393-414. [PubMed: 1091656] [MGI Ref ID J:84317]
Niwa A; Kumaki K; Nebert DW; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. Distinction between the 'responsive' homozygote and heterozygote at the Ah locus. Arch Biochem Biophys 166(2):559-64. [PubMed: 1119809] [MGI Ref ID J:84316]
Poland A; Glover E. 1990. Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles. Mol Pharmacol 38(3):306-12. [PubMed: 2169579] [MGI Ref ID J:34840]
Poland A; Glover E; Taylor BA. 1987. The murine Ah locus: a new allele and mapping to chromosome 12. Mol Pharmacol 32(4):471-8. [PubMed: 2823093] [MGI Ref ID J:8895]
Poland A; Palen D; Glover E. 1994. Analysis of the four alleles of the murine aryl hydrocarbon receptor. Mol Pharmacol 46(5):915-21. [PubMed: 7969080] [MGI Ref ID J:22144]
Robinson JR; Considine N; Nebert DW. 1974. Genetic expression of aryl hydrocarbon hydroxylase induction. Evidence for the involvement of other genetic loci. J Biol Chem 249(18):5851-9. [PubMed: 4413562] [MGI Ref ID J:84315]
Schmid FA; Pena RC; Robinson W; Tarnowski GS. 1967. Toxicity of intraperitoneal injections of 7, 12-dimethylbenz[a]anthracene in inbred mice. Cancer Res 27(3):558-62. [PubMed: 6021513] [MGI Ref ID J:26440]
Schmidt JV; Carver LA; Bradfield CA. 1993. Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment. J Biol Chem 268(29):22203-9. [PubMed: 8408082] [MGI Ref ID J:15153]
Smith AG; Clothier B; Robinson S; Scullion MJ; Carthew P; Edwards R; Luo J; Lim CK; Toledano M. 1998. Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism. Mol Pharmacol 53(1):52-61. [PubMed: 9443932] [MGI Ref ID J:45850]
Thomas PE; Hutton JJ; Taylor BA. 1973. Genetic relationship between aryl hydrocarbon hydroxylase inducibility and chemical carcinogen induced skin ulceration in mice. Genetics 74(4):655-9. [PubMed: 4750810] [MGI Ref ID J:5387]Hld related
Bosco A; Crish SD; Steele MR; Romero CO; Inman DM; Horner PJ; Calkins DJ; Vetter ML. 2012. Early reduction of microglia activation by irradiation in a model of chronic glaucoma. PLoS One 7(8):e43602. [PubMed: 22952717] [MGI Ref ID J:191663]
Davis RR; Newlander JK; Ling X; Cortopassi GA; Krieg EF; Erway LC. 2001. Genetic basis for susceptibility to noise-induced hearing loss in mice. Hear Res 155(1-2):82-90. [PubMed: 11335078] [MGI Ref ID J:69679]
Di Palma F; Pellegrino R; Noben-Trauth K. 2001. Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23). Gene 281(1-2):31-41. [PubMed: 11750125] [MGI Ref ID J:73941]
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Han F; Yu H; Tian C; Chen HE; Benedict-Alderfer C; Zheng Y; Wang Q; Han X; Zheng QY. 2010. A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs. Pharmacogenomics J :. [PubMed: 20644563] [MGI Ref ID J:174758]
Hurd EA; Adams ME; Layman WS; Swiderski DL; Beyer LA; Halsey KE; Benson JM; Gong TW; Dolan DF; Raphael Y; Martin DM. 2011. Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome. Hear Res 282(1-2):184-95. [PubMed: 21875659] [MGI Ref ID J:220430]
Johnson KR; Erway LC; Cook SA; Willott JF; Zheng QY. 1997. A major gene affecting age-related hearing loss in C57BL/6J mice Hear Res 114(1-2):83-92. [PubMed: 9447922] [MGI Ref ID J:44966]
Johnson KR; Longo-Guess C; Gagnon LH; Yu H; Zheng QY. 2008. A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice. Genomics 92(4):219-25. [PubMed: 18662770] [MGI Ref ID J:139223]
Johnson KR; Yu H; Ding D; Jiang H; Gagnon LH; Salvi RJ. 2010. Separate and combined effects of Sod1 and Cdh23 mutations on age-related hearing loss and cochlear pathology in C57BL/6J mice. Hear Res 268(1-2):85-92. [PubMed: 20470874] [MGI Ref ID J:163035]
Johnson KR; Zheng QY; Bykhovskaya Y; Spirina O; Fischel-Ghodsian N. 2001. A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice. Nat Genet 27(2):191-4. [PubMed: 11175788] [MGI Ref ID J:67312]
Johnson KR; Zheng QY; Noben-Trauth K. 2006. Strain background effects and genetic modifiers of hearing in mice. Brain Res 1091(1):79-88. [PubMed: 16579977] [MGI Ref ID J:110459]
Johnson KR; Zheng QY; Weston MD; Ptacek LJ; Noben-Trauth K. 2005. The Mass1(frings) mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC. Genomics 85(5):582-90. [PubMed: 15820310] [MGI Ref ID J:97534]
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Zheng QY; Johnson KR. 2001. Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice. Hear Res 154(1-2):45-53. [PubMed: 11423214] [MGI Ref ID J:70964]
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Vaughn JE; Matthews DA; Barber RP; Wimer CC; Wimer RE. 1977. Genetically-associated variations in the development of hippocampal pyramidal neurons may produce differences in mossy fiber connectivity. J Comp Neurol 173(1):41-51. [PubMed: 845286] [MGI Ref ID J:5787]
Animal Health ReportsRoom Number AX8
Room Number MP14
Room Number RB09
Colony Maintenance
Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Breeding Considerations This strain is a good breeder. Diet Information LabDiet® 5K52/5K67
|Pricing for USA, Canada and Mexico shipping destinations
Weeks of Age Price per mouse (US dollars $) Gender 3 weeks $27.50 Female or Male 4 weeks $27.50 Female or Male 5 weeks $27.50 Female or Male 6 weeks $30.15 Female or Male 7 weeks $32.80 Female or Male 8 weeks $35.45 Female or Male 9 weeks $38.10 Female or Male 10 weeks $40.75 Female or Male 11 weeks $43.40 Female or Male 12 weeks $46.05 Female or Male
Standard Supply
Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request.
Supply Notes
- Timed pregnant females are available from the Bar Harbor, Maine facility.
- This strain is available from both the Bar Harbor, Maine and Sacramento, Calif. facilities.
- Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available.
Select the cell line of interest to go to the cell line data sheetBALB/cByJ AC383/GrsrJ mES cells
BALB/cByJ-PB150.18 mES cells
|Pricing for International shipping destinations
Weeks of Age Price per mouse (US dollars $) Gender 3 weeks $35.80 Female or Male 4 weeks $35.80 Female or Male 5 weeks $35.80 Female or Male 6 weeks $39.20 Female or Male 7 weeks $42.70 Female or Male 8 weeks $46.10 Female or Male 9 weeks $49.60 Female or Male 10 weeks $53.00 Female or Male 11 weeks $56.50 Female or Male 12 weeks $59.90 Female or Male
Standard Supply
Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request.
Supply Notes
- Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available.
- This strain is available from some international Charles River (CR) breeding facilities in Japan and/or Europe. For more information, see the Worldwide Distributor List for JAX® Mice.
Select the cell line of interest to go to the cell line data sheetBALB/cByJ AC383/GrsrJ mES cells
BALB/cByJ-PB150.18 mES cells
In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.
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Thursday, June 20, 2013
Dear Editor,
When we realize we have made the right decision it brings immense satisfaction. Last year I was part of a search committee that was charged with selecting the new president of Columbia College. If you have never been on a search committee, I can assure you it is a most difficult task in which every participant is mindful that the decision will have a lasting impact.
Our dedicated search committee selected Elizabeth Dinndorf, J.D., as Columbia College's 18th President. She was a nontraditional candidate as a business and finance executive, and a loyal alumna of a Minnesota women's college with many years of leadership and service on its Board of Trustees. In other words, she was the right woman at the right time!
As a private Methodist-affiliated college, our goal is to educate and prepare our graduates to achieve personal and professional success in today's world through our distinctive woman's college and our co-educational evening and graduate programs.
President Dinndorf has already initiated new cutting-edge programs that make this even more attainable for students who understand the value of personalized attention and a uniquely supportive learning community. Check out our "You're on Your Way" initiative or our new Momentum Scholarship program. These opportunities and others make Columbia College a true home for developing and promoting leadership skills in all our students, something we have been doing for more than 150 years.
I want South Carolinians and our 10,000-plus alumnae to know great things are happening at Columbia College under the leadership of President Dinndorf. If the coming years are anything like this first energizing year, we are truly "on our way" to an even brighter future. I'd also like to express my thanks to our new President and the dedicated faculty and staff for all they do to make this historic and wonderful institution the special place it is.
Marlene Myers
Member, Board of Trustees
Columbia College
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My Pizza Oven: Tailbiter's FrankenEgg
If you follow My Pie Monday, then you've already seen Tailbiter's pies. Eric hails from Tulsa, OK, where he's a software engineer by day and a pizza maven by night. Now we have the pleasure of taking a look at his homemade pizza dome, handily designed to fit his Big Green Egg. More


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The Aiken Department of Public Safety is investigating a Wednesday night shooting that left a man hospitalized.
The shooting happened about 10:30 p.m. at Colleton Court Apartments on the 1600 block of Colleton Avenue, according to a report. Officers found 35-year-old Anthony Oakman, of Colleton Avenue, lying face down on a curb in front of the apartments with a gunshot wound to the head.
Oakman was transported to Georgia Regents Medical Center, where he remained on Thursday, according to Sgt. Jake Mahoney. No arrests had been made as of press time on Thursday. Mahoney said investigators were developing leads throughout the day.
"There was a dispute between two individuals," he said. "The victim was approached by the unidentified suspect. There was an altercation between the two. The victim was shot by the suspect."
A weapon was not recovered from the scene; however, investigators found three bullet shell casings.
"There were witnesses to the crime that have been interviewed by Public Safety officers," Mahoney said.
Teddy Kulmala covers the crime beat for the Aiken Standard. He is a graduate of Clemson University and hails from Williston.
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Earlier this week, Pfizer announced the failure of the first Phase III trial of the anti-amyloid antibody bapineuzumab — "bapi" for short — as a treatment for Alzheimer's disease. Pfizer announced the news unilaterally, without partners Elan and Johnson & Johnson, which suggests that the syndicate disagreed about how and when to communicate the data. Nonetheless, the press release clearly implies that even the industry's best statistical pickaxes couldn't unearth a "spin-able" result. I expect bapi's remaining pivotal studies, as well as those conducted by Eli Lilly — the company is conducting Phase III trials of a similar drug, called solanezumab — will fail over the next few months.
I have been a professional investor focused on healthcare for 15 years. In 2008, when investor excitement about bapi drove Elan to a $17 billion market capitalization, I was nearly alone in my skepticism. As any short seller can tell you, it's incredibly difficult to be the only bear in the room as the stock soars.
Fortunately for me, the bulls were wrong. Almost exactly four years ago, bapi's Phase II studies flopped, Elan shares plunged, and investors forgot about the drug.
Yet instead of discontinuing development or testing any new, post hoc hypotheses in small prospective studies, Elan and Wyeth — not yet part of Pfizer — made a mind boggling "go" decision later that year. Despite an extremely inconsistent Phase II dataset, the companies initiated a series of massive pivotal trials, which enrolled more than 4,100 patients worldwide. (Although Pfizer continued the Phase III studies after the Wyeth merger, management should be commended for at least foisting half of the development risk onto Johnson & Johnson.)
After a few years and at least $500 million in incremental R&D spending, Wall Street bulls began whispering enticing phoenix-from-the-ashes tales as bapi's Phase III data approached. Some investors took the bait again, buying for a second time into the faulty "if the drug works, it will be huge" mentality. Even after this week's failure, several Street analysts still believe bapi might work in one of the remaining Phase III trials. (The failed study tested patients with an unfavorable genetic mutation, called ApoE4. Two of the four pivotal trials enrolled patients without the ApoE4 allele.)
Unfortunately, wishful thinking doesn't make a drug effective. Bapi is no exception.
Everyone loves a good pat on the back, but the goal of my first Forbes column is not self-congratulatory. Instead, I want to use bapi's rise and fall as a proxy to discuss the surfeit of unwarranted optimism that plagues the healthcare industry.
In healthcare, audacity too often belongs to the skeptics, rather than to the hopeful. Few openly vote against new medical technology, whether by shorting or avoiding the stock, denying additional R&D outlays, or putting skeptical pen to paper. This unwillingness to suspend belief leads to misdirected frustration — at the FDA or investors short the relevant stock — and misaligned R&D spending.
The motivations for this excess optimism vary depending on the constituent. Investors dream of the biotech stock that rapidly quadruples and yields a vast fortune. Executives lust for the double reward of soaring options and cured patients. The media craves the humanity of medicine — the innocent child cured of a rare cancer, the heart attack patient saved by a stent, and even the gossip-fueled indulgences of cosmetic surgery — because it makes for compelling stories.
Yet these superficial explanations obscure a deeper reason for this persistent hopefulness. As inexorable participants in the system — patients of the past, present, or future — we all yearn for solutions to forestall our bodies' inevitable betrayal or revolt.
My Forbes blog — The Pill and the Prick — will take an unvarnished look at every area of healthcare, both therapeutics (the pill) and services (the prick). My goal is to be thought provoking, fair, and unwaveringly honest.
Skeptics are often lambasted for being insensitive or, at worst, inhuman. I've often heard even the most seasoned investors counter a bearish view with a schoolyard-like retort — "What if your parent had this disease?" So let me be clear. I don't rejoice at anyone developing Alzheimer's disease. Brilliant family friends have deteriorated precipitously before my eyes. I know firsthand the consequences of this horrible disease and have tremendous empathy for patients' suffering.
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Menu - SS Kamo Maru, NYK Line, Dinner, 6 Mar 1939 Reg. No: HT 6322
- Summary:
- Dinner Menu for the N.Y.K Line ship SS 'Kamo Maru', on the Japan-Australia Service, for the 6 March 1939. It was collected by Hanns-Georg von Laue and his sister Marie-Charlotte during their voyage from England to Australia as migrants in 1939. The children of a German father and Jewish mother, both eventually left Europe for England after facing persecution. They obtained passage to Australia as refugees with the assistance of the Quakers in England. They departed on the Japanese ship SS 'Husimi Maru' in January 1939; then changed to the SS 'Kamo Maru' for the Australian leg.
Hanns-Georg first settled in South Australia, working on a sheep station. When war broke out he tried to join the Australian Army but was classified an enemy alien and remained under surveillance throughout the War. After the war he continued to work on remote stations, then moved to his own fruit block in Renmark where he married and raised a family. In the early 1950s, they moved to Melbourne where he established a bookbinding business. Marie-Charlotte sister remained in Adelaide, first as a nanny and then a dental nurse and would later marry a German refugee.
- Description:
- Cover features wrap around 'wood block' printed mountain scene in black, blue, white and red, opens to dinner menu
- Acquisition Information:
- Donation from Rhonda von Laue, 2004
|19.00 cm (Height), 12.90 cm (Width)
More information
|Tagged with:
|german communities, german immigration, immigration, jewish communities, jewish immigration, immigrant voyages, immigrant shipping, shipboard travel, refugees, menus, ship memorabilia
|Themes this item is part of:
|Migration Collection, Transport Collection
|Primary Classification:
|Secondary Classification:
|Travel - Shipboard Life
|Tertiary Classification:
|Manufactured For:
|NYK Line, Japan, 1939
|Place & Date Used:
|., 6 Mar 1939
|Hanns-Georg von Laue, 6 Mar 1939
Collected By
|Marie-Charlotte von Laue, 6 Mar 1939
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I find Reminders through iCloud is pretty flaky. I will mark something as complete on the iPhone, and later have to mark it again on the iPad or on icloud.com. It also doesn't always disappear unless I change reminder lists and come back to it. Also, recurring reminders sometimes set bizarre dates when completed....for instance, if I set a reminder to remind me every Wed at 8pm, and mark it as complete, sometimes it'll set the next one up to remind me at Mon at noon. The sync is really poor - and needs work. If I mark something as done, I want it done. I don't want to see it again unless I go looking for it in the completed section. With that, I kind of fall in line with Rene's take that 2013 will be the year they MUST focus on iCloud. I know sync is hard, but these are interface shortfalls that Apple must understand. And yes, I've provided this feedback through Apple's iCloud feedback page.
How to mark items as complete in Reminders on iPhone and iPad
The built-in Reminders app makes for a great way to keep you on task and organized. Once you've learned how to create reminders, you can view them at any time on your iPhone and iPad. Then, when you complete them, you can just as easily mark them as complete so they disappear from your Reminders app.
Not sure how? Follow along.
- Launch the Reminders app from the Home screen of your iPhone or iPad.
- Find the item that you'd like to mark as complete.
- You'll notice a little check box to the left of it. Tap on it.
- You'll now notice that the item is marked as complete and it will disappear from that list.
- If you ever need to view it again or you tap on the wrong reminder to mark as complete, you can restore it or view it again from the completed list within the Reminders app.
Have something to say about this story? Leave a comment! Need help with something else? Ask in our forums!
Reader comments
How to mark items as complete in Reminders on iPhone and iPad
Is this a joke article? An entire article on how to tick a checkmark in an app?
Personally, I find Reminders has been ruined since the first update where they changed the list behaviour from swiping to tapping. If you have more than one list it's now so awkward to switch between them that it's hardly worth booting up the app at all.
This exactly. I cover everything from very beginner things to how to completely tear apart your devices. Right now, we are working on rounding out basic features. After that, intermediate stuff will start up again.
I get lots of emails from people specifically asking for this kind of stuff because they have relatives or parents or even grandparents with iPhones that have no idea what to do, let alone how to create a reminder and utilize the full functionality. Which is why we do this, and then round them up into huge guides on reminders, siri, icloud, notes, messages, etc...
Keep up the good work Allyson.
The swiping behavior is actually still there, you just need to swipe on the title of the list rather than anywhere.
Personally I find it to be a good compromise. Previously I would frequently try and swipe to delete an item I wanted to get rid of and couldn't, now I can do both.
Thank you, thank you, thank you! It really bothered me that I couldn't swipe between lists anymore and never would've noticed you can still swipe on the title if I hadn't read this. Grateful!
Please don't take this the wrong way. I love how to tips and tricks, but really? How to mark items as completed in Reminders?
If this were posted on a blog specifically for beginners, I could see it being useful. However, this is posted on iMore.com. How many computer neophytes are going to be reading this blog?
Who is this post written for? Me? Of all my relatives that are not computer savvy, none of them would even know that this site exists and if they had a question of how to do something like this, they would ask either myself, my wife or my cousin who actually do know something about computers before they would ask Google.com or other search engine how to do it.
Why not have tips/tricks that are of a slightly higher level?
Actually, we do get quite a lot of beginner users. A lot of times they are referred from other relatives. I can't tell you how many emails I've gotten saying someone referred a relative new to iOS to iMore and now they read it every day for the beginner tips. It goes both ways. Google and referrals/word of mouth.
imore.com/tips houses everything including more advanced tips & tricks. once we finish up reminders, we probably will go to something more intermediate to advanced again. but we tend to rotate different topics. reminders just happens to be a beginner topic.
Fair enough! :) I had forgotten about imore.com/tips. There is a vast catalog of video tips that you all have created. It just seems like this tip is as basic as: "How to wake your iPhone... Press the Home button or the Sleep/Wake button, then slide your finger across the "Slide to Unlock" control." However, I can see a place for even that kind of tip.
I know I shouldn't have said anything, it was just so obvious.


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Shop All Jewelry
NLZ10878 In Stock
This Vintage Style Filigree Birthstone Heart Pendant is set in beautiful sterling silver. A perfect gift for mom, she will enjoy her five of her loved ones birthstones set into this filigree heart necklace. This 5 birthstone filigree heart pendant comes on your choice of a 16", 18" or 20" rolo rhodium chain. Build your silver heart pendant with your choice of 12 Austrian Crystal birthstones.
• Filigree Heart Pendant
• 5 Stones
• Variety of Chain Lengths Available
• .925 Sterling Silver
Eve's Addiction.com wants you to be a happy customer. We want you to be completely satisfied with the sterling silver jewelry that you receive from us, as we only sell high quality silver and cubic zirconia cz jewelry. We do understand that you may not like your purchase for some reason.
You may return or exchange your jewelry within 60 days of purchase if you are not satisfied with it. The jewelry must be returned in its original condition for a refund or exchange. Engraved, personalized, photo, monogram, name and initial, chocolate and clearance items are not returnable or exchangeable.


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Welcome to Clover Downs Estate, a luxury bed and breakfast retreat in stunning rural surroundings near Rotorua. Enjoy the comfort of superior accommodation while experiencing authentic New Zealand farm life.
Clover Downs is a unique place to stay. Situated just 15 minutes from Rotorua in the secluded country setting of Ngongotaha, it is a B&B farmstay experience like no other, catering for single travellers, couples and families. Large comfortable rooms provide you with a place to rest and relax in peace and tranquillity, while sheep, ostriches and deer graze on the green paddocks surrounding the house.
Clover Downs gives you an unparalleled opportunity to get up close to farm animals. Take the complimentary farm tour, feed ostrich by hand, see trained sheep dogs rounding up sheep, get within a few feet of a majestic deer and feed the Alpaca's. In the evenings, enjoy a glass of wine on your own private veranda overlooking lush pasture.
Your hosts, Mike and Sharon Ferris, will ensure that your retreat is comfortable and memorable. They can also help arrange other activities so that you can experience all that Rotorua has to offer – geothermal wonderlands with geysers and bubbling mud pools, the rich Maori culture, excellent fishing, sightseeing and other exciting pursuits. Or you can travel further afield to Tauranga, Mount Maunganui, Whakatane, Taupo and Waitomo.
Stay at Clover Downs Estate, enjoy fine country accommodation, get close to nature, breathe the country air. An authentic kiwi experience.


text: Last Sunday at Weiss Playlot in southwest Detroit, a group of family and friends were enjoying a wonderful evening."I decided it was getting too cold outside," Tiffany Garcia said.So they packed up and left the park, but as soon as they were walking, one of the little girls saw something really big running right behind them."I just heard her say, 'There's three dogs running,'" Garcia explained. "We're all running. I fell by the tree.""Three dogs attacked me. They ripped my skin open.""It was not gushing blood, but it was a lot of blood."Garcia said she was bitten several times before finally being able to free herself from her attackers."911, I called them," Garcia said. "They never showed up.""It's kind of sad that they don't show up," she added. "They don't care."A few hours later, however, police and EMS crews did showed up to the scene and then to Oakwood Hospital where Garcia was getting her first round of rabies shots to protect herself from vicious dogs that neighbors told us have gotten lose and bitten before.The owner stopped by Tuesday to see how much damage his dogs had allegedly done."I really feel bad," said Stanley Zepeda. "I don't know what happened.""I need to protect my property and my family, too, because over here it's really dangerous.""I just want to say I'm so sorry, and whatever I got to do, I'm going to do for you."Garcia and her family were told Animal Control was going to come investigate to determine the fate of the dogs and their master, but they are still waiting. One family member said the dogs "need to be put down."We were told the three dogs are German shepherd mixes. Meanwhile, Detroit police said they are aware of the situation. Animal Control will be out to investigate and dig a little deeper looking into some complaints from the past.The owner said he will do a better job securing his animals so they do not get out and attack anyone else again.


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Australian Bureau of Statistics
2069.0 - Census DataPacks at a Glance, 2007 to 2012
Latest ISSUE Released at 11:30 AM (CANBERRA TIME) 28/08/2007 First Issue
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Census DataPacks at a Glance provides a short two page overview of the Census DataPacks product. It has been designed to answer questions you may have about the features of Census DataPacks; the format it will be available in; what geographic areas it will be available in, and what the cost of the product will be.
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TDEC is responsible for managing, protecting and enhancing the quality of the state's water resources through voluntary, regulatory and educational programs.
Division of Water Resources
Water Quality
Ensuring a safe water supply is essential for daily living. TDEC oversees the design, construction and operation of public works systems, certifies laboratories and water suppliers that conduct drinking water testing and conduct training and certify water supply system operators.Read More
Fleming Training Center
Septic & Decentralized Systems
A septic system is a type of small-scale sewage treatment system common in areas with no connection to main sewage pipes provided by local governments or other entities.Read More
Watershed Stewardship
TDEC provides the technical basis for setting the state's water quality standards, developing the rules and guidance for implementing these standards and conducting permitting, compliance and enforcement programs to establish standards throughout the state.Read More
Water Notices & Hearings
Mining Information & Permits
Drought Planning
State Revolving Fund


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Johnston Named Athlete of the Week
MORGANTOWN, W.Va. - Senior Colin Johnston (141) tallied WVU's first win and takedown against No. 5 Oklahoma State on Saturday. Jan. 18. Johnston wrestled No. 12 Anthony Collica to the mat twice in the first period. Collica recorded an escape and reversal to bring the bout to 4-3 in Johnston's favor midway through the first period. An escape by Collica to start the second knotted the match at four, but Johnston took Collica down for a third time and turned him on his back for a two-point nearfall to earn the decision, 8-4.
Johnston has now defeated back-to-back ranked opponents, recording a decision over then-No. 20 Dan Neff of Lock Haven, 12-7, on Jan 4. Johnston leads the Mountaineers with 27 takedowns in his team-high 11 dual-match victories this season, with his lone loss coming against then-19 Joe Spisak of Virginia on Nov. 2.
WVU Athletes of the Week
Winter 2014
Week 1: Asya Bussie, women's basketball
Week 2: Bryce Bohman, swimming & diving
Week 3: Colin Johnston, wrestling
This Week in Women's Basketball
The Mountaineers return to the court for a two-game road swing, starting at 7:30 p.m. ET, on Wednesday at Texas Tech and closing out the week with a 4 p.m. matchup at Texas on Saturday, Jan. 25 … WVU trails Texas Tech 2-0 in the all-time series, while leading Texas 3-1.
Last Week in Women's Basketball
WVU went 2-0 in Big 12 action … junior guard Linda Stepney used a career-best scoring outing to help the Mountaineers to a 73-59 win over No. 13/11 Iowa State, Wednesday at the Hilton Coliseum … senior guard Christal Caldwell paved the way to a 77-63 WVU victory over Oklahoma on Saturday at the WVU Coliseum … Stepney had 16 points at ISU and recorded a career-best 17 points against OU, while Caldwell had 11 points at Iowa State and recorded 23 to lead WVU against Oklahoma.
Notes & Quotes
The Mountaineers are 16-2 overall and 5-1 in Big 12 play … sophomore guard Bria Holmes leads four players averaging scoring numbers in double figures with 13.9 points per game … senior center Asya Bussie averages 13.1 and senior guards Christal Caldwell and Taylor Palmer average 12.3 and 11.1 points per game, respectively … WVU averages 77.8 points per game as a team … Bussie leads WVU's rebounding with 7.3 boards per game, and junior forward Crystal Leary averages 4.9 rebounds per game.
Coach Mike Carey: "Give our girls a lot of credit. We came off a big win, came home, and Oklahoma has a great team. They run a lot of stuff and a lot of stuff well. Overall, I'm very pleased; our girls fought hard."
This Week in Wrestling
The West Virginia University wrestling team is idle this week.
Last Week in Wrestling
The Mountaineers (9-3, 0-2 Big 12) snapped their six-match win streak against No. 5 Oklahoma State, 30-6, on Saturday, Jan. 18.
Notes & Quotes
Senior Colin Johnston defeated a ranked opponent for the second consecutive match, defeating the Cowboys' No. 12 Anthony Collica by decision, 8-4 … Johnston leads the team with 27 takedowns this season and has a team-high 11 dual-match wins … freshman Leo Trindade won his third consecutive match, defeating OSU's Darnell Bortz, 8-6.
Coach Craig Turnbull: "Colin is becoming more confident. He struggled last year with his weight and injuries, and it snowballed to where it took some of his confidence. Now he is beyond it. With two wins over ranked opponents, he is sticking his chest out a little bit more, and it is coming at the right time in the year."
This Week in Swimming & Diving
The teams are off next week before they hit the road on Jan. 31 and Feb. 1 ... the men will be traveling to Columbus, Ohio to face the Buckeyes of Ohio State on Jan. 31, while the women's team will be traveling to Athens, Ohio to face Ohio and Iowa State on Feb. 1.
Last Week in Swimming & Diving
The West Virginia University men's swim team earned its first-ever Big 12 Conference win in a split dual meet at TCU on Saturday. The women's team fought hard, but ultimately fell to TCU 164-121.
Notes & Quotes
The men's team earned their win by a score of 167-133, while the women's team fought hard, but ultimately fell to TCU 164-121 … in the men's 200 medley relay, the "A" team of senior Bryce Bohman and juniors Chris Brill, Julien Vialette and Tim Squires won the event with a time of 1:31.45 … in the men's 200 free, Glegg took the event with a time of 1:41.11 … in the men's 100 back, Bohman scored the win with a time of 48.54 … in the 100 breast, junior Jenelle Zee won the event for the women with a time of 1:05.88 ... for the men, Brill placed second (58.14) … in the women's 50 free, Gillmore won the event with a time of 24.12 … in the men's 50 free, Vialette won the event with a time of 21.28 … in the men's 100 free, Marsh scored the win with a time of 46.54 … in the men's 500 free, Cobbe earned a key win the event with a time of 4:38.67.
For the divers, the women's team took three of the top four spots on the 1-meterd dive ... junior Haily VandePoel won the event with a score of 277.94 … on the men's 1-meter, sophomore Keith Carmichael posted the top score in the event for the Mountaineers this season and placed first (325.95) … on the women's 3-meter, VandePoel earned another win with a score of 318.15.
This Week in Track
Last Week in Track
West Virginia competed in the WVU Invitational on Saturday, Jan. 18 at the WVU Shell Building ... the Mountaineers recorded 11 first-place finishes, however no team scoring was kept.
Notes & Quotes
Senior Katlyn Shelar recorded her second first-place finish of the season in the pole vaule, posting the second-best mark (3.90 meters) in indoor program history ... senior Stormy Nesbit placed first in the triple jump, recording the second-jump (12.42 meters) in indoor program history ... junior Karissa Knabenshue claimed first place in the shot put ... Knabenshue's throw of 12.99 meters was the third-best mark in indoor program history.
Coach Sean Cleary: "I am excited with the way Karissa, Stormy and Katlyn competed today. All three recorded performances that fall in the top three all-time in program history. From what we saw today, all three can go much further and higher over the next few months."
This Week in Rifle
The No. 3-ranked Mountaineers (7-0, 5-0 GARC) will travel to Murray, Ky., this weekend for the Winthrow Invitational on Friday, Jan. 24 … they will also shoot at Great American Rifle Conference (GARC) foe, No. 10-ranked Memphis, on Saturday, Jan. 25.
Last Week in Rifle
WVU defeated GARC foe No. 14 NC State to open its spring semester of competition, 4707-4604 … the Mountaineers won smallbore, 2342-2274, and air rifle, 2365-2330.
Notes & Quotes
The victory over NC State boosted the Mountaineers' home record to 5-0 … WVU's smallbore shot of 2342 is a season high … newcomer junior Ziva Dvorsak had a match-best aggregate score of 1183, winning smallbore with a 589 score and finishing third in air rifle with a 594 mark … junior Maren Prediger won air rifle with a shot of 597 (100-99-100-99-100-99) … sophomore Patrick Sunderman shot a career-best 590 air rifle and placed fifth … sophomore Garrett Spurgeon finished second in smallbore with a season-best 587 mark.
Coach Jon Hammond: "This was a good way to start the spring season. We accomplished what we set out to do. Everyone is working hard and improving. We have a lot more strength on this team now, and everyone is shooting with a bit more freedom. I think the break in the schedule was good for this team. Everyone shot solid today, and they all put in a good performance."
This Week in Gymnastics
The West Virginia University gymnastics team (1-3) opens its 2014 home season against NC State on Sunday, Jan. 26, at 3 p.m., at the WVU Coliseum … Sunday is a "Dollar Day," and all tickets, hot dogs, popcorn and Coca-Colas are available for $1 each … WVU students get in free with a valid student I.D. … Sunday also is "Poster Day," and all fans can pick up a 2014 gymnastics schedule poster featuring the Mountaineers.
Last Week in Gymnastics
The Mountaineers concluded their two week, season-opening road trip with a narrow 193.675-193.5 loss at Maryland on Jan. 17 … senior Hope Sloanhoffer earned her first all-around win of the year (38.75) and finished first on vault (9.875), while freshman Alexa Goldberg won bars (9.875) for the second straight week … Sloanhoffer also paced the team on floor and finished third (9.8), while junior Lia Salzano placed a team-best second (9.675) on beam … as a team, WVU scored wins on vault (48.9-48.85), bars (48.775-48.5) and beam (47.425-47.4) … UMD earned the floor win (48.925-48.4).
Notes & Quotes
WVU was ahead going into the fourth rotation, but the Mountaineers suffered three falls on beam … freshman Nicolette Swoboda finished second in the all-around (38.65) … Sloanhoffer's vault score was her best since 2012 … senior Erica Smith scored 9.8 on bars for the second straight week and placed second overall … Swoboda tied for third on vault with a career-best 9.825 score … despite the loss, WVU continues to lead its all-time series with UMD, 36-16-1 … the two teams will meet again in College Park, Md., on March 16 … WVU owns a 24-14 series advantage over the Wolfpack.
This Week in Tennis
The West Virginia University tennis team travels to Charleston, W.Va., to take on Liberty on Saturday, Jan. 25, at 3 p.m.
Last Week in Tennis
The Mountaineers (0-1) fell to Akron (1-0) 4-3 in their spring opener on Friday, Jan. 17.
Notes & Quotes
The freshmen tandem of Oana Manole and Kaja Mrgole continued their momentum from the fall, recording a victory in doubles over the Zips' Caroline Harpainter and Karolina Maksimava, 6-3 … Mrgole, playing at No. 3 singles, defeated Akron's Madison Cohen, 6-7, 6-0 (10-7) … in the No. 4 singles position, Manole defeated Karolina Maksimava, 6-1, 7-5 … Tsui evened the score 3-3 in the No. 6 singles spot after downing Shannon Newnes, 6-3, 6-3.
Coach Miha Lisac: "It is a starting point for us, and it is important that we keep learning from these matches. I thought it was a good match on both ends and that we battled hard. We put ourselves in a position to be successful, but we need to get better at taking advantage of late situations."
Big 12 Media Days: Dave Wannstedt
Big 12 Media Days: Karl Jospeh
Men's Basketball: Bahamas Preview
Womens Soccer: Kadeisha Buchanan Press Conference
Big 12 Media Days: Dana Holgorsen
Women's Soccer: Amanda Hill and Mocha


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Through the Plain Camera: Small and Shapely Pleasures in Contemporary Photography
In 1967 the Museum of Modern Art in New York unveiled a revolutionary show, New Documents, which heralded the arrival of a new photographic style, one that prized ordinary subjects captured in a snapshot-like fashion. The exhibition, which featured the works of Diane Arbus, Lee Friedlander and Gary Winogrand, was organized by the late John Szarkowski, a man whose 2007 New York Times obituary called him "a curator who almost single-handedly elevated photography's status in the last half-century to that of a fine art." Szarkowski was moved by the intimacy and personal exploration of a new generation of photographic artists, writing in the text that accompanied New Documents that "(t)heir aim has been not to reform life, but to know it." Today, almost 45 years after he wrote those words, their influence can still be felt.
Through the Plain Camera: Small and Shapely Pleasures in Contemporary Photography, which runs at Haverford's Cantor Fitzgerald Gallery October 21 through December 11, gathers together some of the young voices in contemporary photography who are working from and grappling with Szarkowski's legacy. In the show's 36 images, we see intimate, unposed moments seemingly snapped from the daily lives of the photographers: a stain on a sofa, a bar of soap left on the sink, a perfectly wrapped package of Chinese noodle soup. These casually captured, private moments—most of which are devoid of human subjects—feel at once deeply personal and specific to the lives of the artists and yet also broadly universal and relatable to the viewers. They are lively and expressive, but also enigmatic.
Curated by Sarah Kaufman '03 and Rebecca Robertson BMC '00, both former students of Professor of Fine Arts William Earle Williams, Through the Plain Camera celebrates photographers who take pictures that describe and yet transcend everyday experience, suggesting something about the specific interior lives of these artists. Inspired by Szarkowsky's writing, Kaufman and Robertson have gathered unconstructed, unmanipulated images, which represent direct photographic interaction with the world as it is, so that we may all look at their commonplace subjects with new eyes. "There are different kinds of responses that you can have looking at the world around you," says Kaufman, who is a visiting assistant professor of art at Ursinus College. "I would hope that people looking at the show could take it back with them and start to think about what kinds of meanings their own experience can have."
Through the Plain Camera features the work of five photographers: Jessica Backhaus, Elizabeth Fleming, Vita Litvak, Christian Patterson and Shen Wei. The eight pieces by German-born, Paris-educated New York/Berlin resident Backhaus capture brief moments in time in which a cup of coffee has been spilled or a can has just been crushed. The 10 photos of household minutiae—dust bunnies under a bed, a broken lightbulb—by New Jersey-based Fleming are carefully culled from two series, "Strange Happenings" and "Life is a Series of Small Moments." The six shots by Moldovan-born Litvak, who graduated from Haverford in 2002, bring the mostly domestic show outside with her photos of trees, stone hedges and exterior walls of buildings. The five richly detailed shots by Brooklyn-based Patterson are all drawn from the same series, "Concrete Fiction," in which transient moments in man-made spaces—a glimpse at a stage floor or a van window—are more notable for their evocative color and pattern than for their subjects. And the seven photos by Wei were all taken during a return trip to his Chinese homeland after years of living in New York and included in his recent show and book, Chinese Sentiment. They capture quiet, private moments of Chinese life in a palette of cool grays and other muted colors.
The opening reception for Through the Plain Camera will take place Friday, October 21, from 5:30 p.m.–7:30 p.m. in the Gallery. The show's gallery talk will be held Tuesday, October 25, at 4:30 p.m.
Overseen by the John B. Hurford '60 Humanities Center and located in Whitehead Campus Center, the Cantor Fitzgerald Gallery is open Monday-Friday 11 a.m.–5 p.m., Saturdays and Sundays 12–5 p.m., and Wednesdays until 8 p.m. For more information, contact Matthew Seamus Callinan, Campus Exhibitions Coordinator, at (610) 896-1287 or email@example.com.
Haverford College is located at 370 Lancaster Avenue, Haverford, PA, 19041
Office of College Communications 610-896-1333 email@example.com


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Association of Reproductive Health Professionals
1901 L St. NW, Suite 300, Washington, DC 20036
Phone: (202) 466-3825 | Fax: (202) 466-3826
Website: www.arhp.org
Principal Staff:
Wayne Shields, President & CEO
Ellen L. Cohen, Director of Education
Amy Swann, VP of Operations
Rebecca Sager, Director of Development
Beth Robbins, Director of Communications
Beth Jordan, Medical Director
Type of Organization: National Grassroots/Advocacy
Founded: 1963
Mission Statement:
The Association of Reproductive Health Professional (ARHP), founded in 1963, is a multidisciplinary association of professionals who provide reproductive health services or education, conduct reproductive health research, or influence reproductive health policy.
ARHP educates healthcare professionals, policy makers and the public. The organization fosters research and advocacy to improve reproductive health.
Subject Expertise:
Reproductive health
Annual Meetings/Conferences:
Reprodcutive Health 2012
September 20-22, 2012
New Orleans, LA


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