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The Longest Way Home: One Man's Quest for the Courage to Settle Down (edition 2012)
by Andrew McCarthy
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The Longest Way Home: One Man's Quest for the Courage to Settle Down by Andrew McCarthy
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Who of our generation hasn't heard of Andrew McCarthy? His early movies and Brat Pack reputation marked him as one of the actors that I'd followed in my teens (Pretty in Pink, Taps, St. Elmo's Fire, and Less Than Zero). He'd represented an uncertain, sensitive, slightly lost youth. I read his memoir The Longest Way Home largely because I wanted to know more about the actor in his youth.
Andrew McCarthy's writing is clear, vivid, and well crafted. His book is part travelogue and part memoir as he explains his difficulty committing to the mother of his daughter and the woman that he loves. As he talks about the places that he visits, he shares the role that travel and writing has played in his life - both in finding himself and helping him interact with the people he cares about. We are taken to Patagonia, the Amazon, the Osa, Vienna, Baltimore, Kilimanjaro, and Dublin.
While The Longest Way Home does give us better insight into Andrew McCarthy, even as a longtime fan of sorts I wasn't invested in learning or delving into his issues. I think for someone looking for travel writing and with a deep fondness for Andrew McCarthy, the book will prove a satisfying read. Personally, I had a hard time finishing it.
The longest way home was better than I hoped it would be. I have read a number of travel stories by Andrew McCarthy and always enjoyed them but this book explains how the author an 80's movie icon become a travel writer, and even better it surprises the reader by exposing you to the insecurities and difficulties that Andrew has and how they have not only shaped who he is as a father, but also as a soon to be husband for the second time. If you are looking for a book about the movies he was in look elsewhere, this is not that book, but if you want to read a book where an author lays out how difficult he can make things for himself and those around him, while at the same time learning from his experiences and as an added bonus learn a out some of the interesting places he has visited, then you will enjoy this book.
It has taken me a long time to finish this book. It isnt badly written. I just could not get interested in it. I have read other travelogues that I enjoyed so I dont think that the format was an issue and I was very interested in the author's inner struggle with committment. I think the two aspects of this book did not mesh well together. I received this book for free via Goodreads First Reads
Andrew McCarthy is an actor I remember from my teenage years, a man who features on a few of my favourite movies. So when I saw that he had a travel book that was about him dealing with his issues around marriage I was intrigued, when I read it I was charmed.
I do empathise with his feeling of being twitchy in crowds and lonely within groups, I know that feeling all too well myself. In this he explores being in foreign countries, actually working for the National Geographic Traveler, and recounting some of his adventures, alongside his relationship with his now-wife and then-fiancee, and with his own issues and through these travels he comes to terms with himself and with his relationships with the people closest to him.
I enjoyed the read, loved the bits about dealing with his issues and with the wedding and D's dealings with him, which came across as very Irish without being twee.
I would recommend it. Not quite five star but damn close
Andrew McCarthy, actor, director and travel writer has written a memoir concentrating on his inability to come to terms with settling down and being married (a second time) and maybe being a more responsible man. Although, I did enjoy the eighties films he was in; it was the title of this book that really intrigued me. I wasn't sure what I would find but enjoyed the stories of his travels around the globe describing in detail places I know I will never travel to. He touches a bit on his acting and his quick rise to fame; his drinking problem; his need for solitude and his dysfunctional relationship with his family. I felt as I was reading this book, it was a journal for the author to come to terms with not only becoming a husband (although they have been together for a long time) but also terms with his life of uncertainly. It shows that he is as human as the rest of us.
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The author, a travel writer and actor, delivers a memoir about how travel helped him become the man he wanted to be, helping him overcome life-long fears and confront his resistance to commitment. From time immemorial, travel has been a pursuit of passion, from adventurers of old seeking gold or new lands, to today's spiritual and pleasure seekers who follow in the footsteps of Elizabeth Gilbert. Some see travel as a form of light-hearted escapism while others believe it has the power to open your mind, forcing you to confront your demons, and discover your true self. The author belongs to this second category of traveler. His memoir follows his excursions to Patagonia, the Amazon, Costa Rica, Baltimore, Vienna, Kilimanjaro, Dublin, and beyond. He uses his wanderlust to examine his motives and desires, and explore his ambivalence about commitment. He ponders his personal life, his acting career, and his impulse to leave home, all building toward one of the most significant moments of his life: his wedding day. His message about the transformative power of travel is universal, and his exploration of the nature and passion of relationships, both fleeting and enduring, strikes a chord with every man and woman who has ever wondered at the vicissitudes of the human heart.… (more)
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Female , 26-30
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I Will Just Pretend to Hug You Till You Get HereYeah... So I think about it often how it would be to hold you tight in my arms, feel your warmth...being lost in that moment for really really long. But you being so shy could not do it, but I did how little … [more]
I Think the Little Things Make Life WorthwhileSmall Things I have learnt to appreciate smaller things in life. In life we get caught so much in the chaos,mayhem and the routinity that we often forget to slow down and enjoy the little things. The early morning… [more]
Superficial Love?I wish I could open up completely to my fiance. I hold back myself from loving, trusting and beleiving him as much I should be doing because I do not want to hurt myself. I find myself dodging all his plans for the future since I am afraid that I would have hope on his words and then build my dreams only to have it crushed. I cannot express my emotions like he does and I guess I don't have so much towards him like he has towards me. I avoid him completely when he starts to get emotional.........I cannot do this for long. In the begenning I thought it was normal that I was holding back myself, since I was hurt several times and was hoping it would get ok with time, but it is not happenning. I… [more]
I don't dareI don't dare to trust someone so muchI don't dare to love someone so muchI don't dare to have much faith in someone...since too much of these can cause tooo much pain!… [more]

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Book category: History
The Hemingses of MonticelloWritten by Annette Gordon-Reed
Winner of the National Book Award and the Pulitzer Prize: "[A] commanding and important book."—Jill Lepore, The New YorkerThis epic work—named a best book of the year by the Washington Post, Time, the Los Angeles Times, Amazon, the San Francisco Chronicle, and a notable book by the New York Times—tells the story of the Hemingses, whose close blood ties to our third president had been systematically expunged from American history until very recently. Now, historian and legal scholar Annette Gordon-Reed traces the Hemings family from its origins in Virginia in the 1700s to the family's dispersal after Jefferson's death in 1826.
In the mid-1700s the English captain of a trading ship that made runs between England and the Virginia colony fathered a child by an enslaved woman living near Williamsburg. The woman, whose name is unknown and who is believed to have been born in Africa, was owned by the Eppeses, a prominent Virginia family. The captain, whose surname was Hemings, and the woman had a daughter. They named her Elizabeth.
So begins The Hemingses of Monticello, Annette Gordon-Reed's "riveting history" of the Hemings family, whose story comes to vivid life in this brilliantly researched and deeply moving work. Gordon-Reed, author of the highly acclaimed historiography Thomas Jefferson and Sally Hemings: An American Controversy, unearths startling new information about the Hemingses, Jefferson, and his white family. Although the book presents the most detailed and richly drawn portrait ever written of Sarah Hemings, better known by her nickname Sally, who bore seven children by Jefferson over the course of their thirty-eight-year liaison, The Hemingses of Monticello tells more than the story of her life with Jefferson and their children. The Hemingses as a whole take their rightful place in the narrative of the family's extraordinary engagement with one of history's most important figures.
Not only do we meet Elizabeth Hemings—the family matriarch and mother to twelve children, six by John Wayles, a poor English immigrant who rose to great wealth in the Virginia colony—but we follow the Hemings family as they become the property of Jefferson through his marriage to Martha Wayles. The Hemings-Wayles children, siblings to Martha, played pivotal roles in the life at Jefferson's estate.
We follow the Hemingses to Paris, where James Hemings trained as a chef in one of the most prestigious kitchens in France and where Sally arrived as a fourteen-year-old chaperone for Jefferson's daughter Polly; to Philadelphia, where James Hemings acted as the major domo to the newly appointed secretary of state; to Charlottesville, where Mary Hemings lived with her partner, a prosperous white merchant who left her and their children a home and property; to Richmond, where Robert Hemings engineered a plan for his freedom; and finally to Monticello, that iconic home on the mountain, from where most of Jefferson's slaves, many of them Hemings family members, were sold at auction six months after his death in 1826.
As The Hemingses of Monticello makes vividly clear, Monticello can no longer be known only as the home of a remarkable American leader, the author of the Declaration of Independence; nor can the story of the Hemingses, whose close blood ties to our third president have been expunged from history until very recently, be left out of the telling of America's story. With its empathetic and insightful consideration of human beings acting in almost unimaginably difficult and complicated family circumstances, The Hemingses of Monticello is history as great literature. It is a remarkable achievement.
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Miranda's February Journal
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|Thu, 02-02-2012 - 4:06pm
Wednesday Feb 1
This week has been great so far - another trainer sent me her competition regime including diet and exercises. The new 4 day split I put together is pretty close to what she had, so I'll stick with my routine. I do have to add more cardio (boooooo.).
The food was the interesting part. Basically they calculated what her calorie needs were with a high level of activity, and reduced that by 500 per day. So if her calorie needs were 2100, then they put her down to 1600 and told her that she had so many grams of carbs, so many grams of protein, and so many grams of fat to take in. The percentages worked out to about 40% Carbs & Protein each, and 20% Fat, plus one high carb day where you ate 50% carbs, 33% protein and 17% fat.
- Calories: 1,316 (39.1% Carb + 34.8% Prot + 26.2% Fat)
- Breakfast: 1 egg, 1/2 cup egg whites + 1 cappuccino
- Snack: 12 Almonds, 1/2 grapefruit, Skinny Pepperint mocha
|Thu, 03-01-2012 - 3:33pm
iv_miranda_d wrote:
Vanessa, I really do believe you can reshape your body with weights to a certain extent - it won't make me taller, it won't give me longer legs, but you can create certain illusions with weight training. And I still haven't found the exercise that gives me bigger boobs. I'll keep looking. LOL
When you find that one - PLEASE share with me!!!
|Fri, 03-02-2012 - 3:34pm
I'm a bit behind on tracking and once again, the last half of the week hasn't been pretty. LOL


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New CNA (what attire and accessories should I buy?) - page 2
Hey everyone, I'm starting a new job (subacute), and I was wondering if there were anyone who knew if I should be buying new scrubs, stethoscope, and the like. Did your facility provide you with scrubs and materials? I'm... Read More
- 0Nov 22, '11 by tothepointeLVNI love Walmart's scrub pants. Now I just wear those and pair them with my more pricey scrub tops from Koi. A good way to stretch your scrub $
- 0Nov 22, '11 by rn/writer GuideTry MarcusUniforms.com. They have a wide selection of brands and styles at reasonable prices. And they have a sale section, too. Most of my stuff is from Marcus. I've always felt the Walmart scrubs were kind of stiff and I don't like the way they fit.
Hope you find out something soon.
- 0Dec 14, '11 by Gennabean,CNAIf you can handle the anxiety of not having instant gratification Of buying new stuff with your new CNA job (I know I can't ;P) then check out allheart.com they have the CUTEST CHEAPEST scrubs. I've bought the CUTEST print tops for like 6 bucks. And if you want solids they have every color under the sun.
Also, I wouldn't recommend buying used scrubs. I mean, you don't know what kind of unholy, ahem, stuff have been on them. Unless, you know, you are planning to wash them in biohazard cleaner and bleach
Have fun and God Bless


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AddOn Repo
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1) Send me a email to dev [at] ispconfig [dot] org if you like to receive the examples for the addon repo.
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Many genetic testing options are available for pregnant women and their health care providers today. The purpose of these tests is to look for certain fetal health problems during pregnancy. Some tests are called "screening" tests and others are called "diagnostic" tests.
Traditional screening tests are used to predict the chance for a pregnancy to have certain chromosome conditions. These tests are not invasive; in that they involve a blood draw from the mother and sometimes an ultrasound. Some screening tests require more than one office visit to perform multiple blood draws and ultrasound examinations at very specific times in pregnancy. Results from many screening tests will provide a "risk score" (such as 1 in 500 or 1 in 50) that describes the chance of a fetus having trisomy 21 (Down syndrome). These risk scores can be confusing. A screening test may be "negative" (or low risk) in as many as 30% of pregnancies affected by one of these chromosome conditions. Also, a screening test will be "positive" (or increased risk) in about 5% (1 in 20) of women who have the test, even though most of these women have healthy pregnancies. This means a woman whose fetus has a chromosome problem may incorrectly receive a negative (or low risk) result, and a woman with a normal fetus may receive a positive (or high risk) result.
Screening tests can help women and their providers decide whether to have an invasive diagnostic procedure. It is generally recommended that patients receiving a "screen positive" result be offered an invasive diagnostic procedure to confirm if the fetus has a chromosome abnormality.
Diagnostic procedures, such as amniocentesis or chorionic villus sampling (CVS), can determine whether a fetus has trisomy 21 (Down syndrome), trisomy 18, or other chromosome conditions. The invasive nature of these procedures can give rise to concern among some patients.
In response to this need, Illumina is proud to offer the verifi® prenatal test, a non-invasive test that detects multiple fetal chromosomal aneuploidies. The test detects three primary chromosomal aneuploidies for trisomies 21, 18 and 13 from a single blood draw as early as 10 weeks estimated gestational age. Trisomies occur when three, instead of the usual two, copies of a chromosome are present.
In addition, Illumina also offers the sex chromosomes test option, which includes the detection of Turner syndrome (Monosomy X), Triple X (XXX), Klinefelter syndrome (XXY), and Jacobs syndrome (XYY), the most common fetal sex chromosome abnormalities (also called sex chromosome aneuploidies). Sex chromosome aneuploidies are conditions in which there is a change from the usual 2 copies of sex chromosomes in males (XY) or females (XX). All of these conditions may cause mental or physical disabilities, with different levels of severity.
This test is available for singleton and twin pregnancies.*
A sample of your blood is drawn and the genetic material is tested. This test uses a technology called "massively parallel DNA sequencing" to count the number of copies of these chromosomes, and then uses a calculation method to determine if there are too many or too few copies of these chromosomes present.
This screening test may be an option for you to consider if:
You have a confirmed singleton or twin pregnancy of at least 10 weeks gestational age, and meet any of the following criteria:
Your test report will include one of three possible results for chromosomes 21, 18, and 13: No Aneuploidy Detected, Aneuploidy Detected, or Aneuploidy Suspected (Borderline Value). Sex chromosomes will be reported as No Aneuploidy Detected or Aneuploidy Detected. In the case of a twin pregnancy, Y chromosome presence will be reported as Detected or Not Detected.
The verifi® prenatal test is a highly accurate advanced screening test that is non-invasive. Genetic counseling before and after testing is recommended. Results of "Aneuploidy Detected" or "Aneuploidy Suspected" are considered positive and patients should be offered invasive prenatal procedures for confirmation. A negative test does not ensure an unaffected pregnancy. Chorionic villus sampling and amniocentesis provide definitive diagnostic information, but are not without risks to you and your baby.
Illumina is excited to be at the forefront of improving noninvasive prenatal testing options with its proprietary technology to evaluate multiple fetal chromosomes across the genome. Founded with strong academic and scientific support from major medical and clinical research institutes, the company is committed to helping clinicians offer the latest in prenatal care to patients.
*The verifi® prenatal test for chromosomes 21, 18, and 13, is available for singleton and twin pregnancies. Sex chromosomes aneuploidy testing is available for singleton pregnancies only. An optional test for twin pregnancies tests for the presence of the Y chromosome.
View the full video for expectant parents presented by genetic counselors to help answer some questions you may have about the health of your pregnancy and introduce your options for prenatal testing.
This screening test is intended for patients at 10 weeks or greater gestation with singleton pregnancies who meet any of the following criteria:


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LLM Discussion Board
LL.M. Discussion Board > United Kingdom - Ireland > LLM vs PhD
LLM vs PhD
Joined: 07 Oct 2009
Posts: 104
LLM vs PhDHi
Thu Apr 01, 2010 07:13 PM
I am currently studying for my master's degree in Switzerland. After that I'd like to pursue either a career in the foreign office or in academia, would you recommend rather a LLM or a PhD? with my degree I would be eligible for both. and then there's also the possibility of the cam Diploma in Intl Law
Both of them I'd love to do in the UK it's public international law that I am most interested in.
thanks and happy easter! J
[Edited by hejonas on 01 Apr 2010]
|Profile P.M.
Joined: 01 Feb 2006
Posts: 121
LLM vs PhDHejonas,
Tue Apr 06, 2010 03:10 PM
I did both of them. They are quite different pursuits. The LLM involves one intense year (actually, slightly less than a full year) of studying but also of close contacts with other students, human interactions that are a sizeable part of what the LLM gives you (and - absent scolarships - gets paid for) in the end.
A phD, although usually involving deep (especially from an intellectual standpoint) exchanges with other people, and although being the occasion for starting strong friendships, is mostly a solitary endeavour (especially when the first half-study-half-refining-your-dissertation-proposal year ends and most efforts are to be concentrated towards writing down your dissertation).
This requires a lot of discipline, focus and, if you already have a job, a sizeable amount of sacrifice. And it lasts years (at least three, or more).
By and large, LLMs are for people who like to study. PhDs are for people that love books above (almost) anything else.
Be sure you do love your subject before entering a PhD program, otherwise there's a fair chance that it converts into suffering and, in the worst cases, withdrawal.
If you want to access fast to your preferred career, a prestigious LLM is quite fine, at least most of the times.
That said, they are both wonderful experiences and a lot can be gained from either one.
Hope I've been somewhat helpful.
|Profile P.M.
Joined: 07 Oct 2009
Posts: 104
LLM vs PhDthanks very much, dam, that was indeed very helpful. I'm drawn to both possibilities alternately and I have still a few months to decide.. may I ask where you did your LLM and doctorate? Please pm if preferred. Do you think to pursue a phd at a UK uni while working around 60% in another country is doable? Did you manage to work? At swiss universities, most phd students work as research assistents at uni, ie more or less 50%.
Tue Apr 06, 2010 03:30 PM
I am also 'already' 24, which leads me more to starting a doctorate after graduation.. However, I've heard so many good things about some LLM programmes that I may end up in the same situation as you obviously did. Would you do it again, ie both LLM and PhD? I understand that eg at Cambridge, doctoral students also take LLM courses...
thanks again!
|Profile P.M.
Joined: 28 Apr 2010
Posts: 1
LLM vs PhDHi hejonas,
Wed Apr 28, 2010 11:22 PM
I'm starting my LLM studies in Sept here in Ireland. I'm going for the part-time (2yr) option; i work full time so its not going to be easy, sometimes we just have to step out of the comfort zone to reach our dreams.
Wish i was your age, i'd go for the LLM first, see how it goes, then consider Phd, the years fly by, make the most of your time; academic year is short, fun time is more enjoyable when you feel you deserve it.
[Edited by Holygrail on 28 Apr 2010]
|Profile P.M.
Joined: 28 Sep 2006
Posts: 272
LLM vs PhDCould anyone tell me what the general admissions requirements are for Ph.D. programs (e.g., with respect to performance on the LL.M.)?
Thu Apr 29, 2010 12:19 AM
|Profile P.M.
Joined: 07 Oct 2009
Posts: 104
LLM vs PhDthanks for your responses.
Thu Apr 29, 2010 12:46 AM
I understand the general requirements are a Master's degree in law, the suitability of proposed research to the institution and the availability of a suitable supervisor.
I probably opt for a specific one-year research degree during which I would be able to attend LLM courses as well, and then return to Switzerland to complete a PhD here, as I was lucky to be offered a PhD position in my current university just today :) that should take me not much more than 3 years hopefully and would be the ideal situation
decided against a three-year phd programme in the uk for I would miss my girlfriend just way too muchshe is currently doing a semester in Paris which is already bad enough
[Edited by hejonas on 29 Apr 2010]
|Profile P.M.


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Spokane Help Wanted Ads
Welcome to Spokane Help Wanted Ads! Whether you are looking for a new job, or a new employee, Spokane Help Wanted Ads makes it easy for job seekers to find jobs in the Spokane area and we provide employers with an affordable and effective way to advertise local jobs. Job Seekers: To find a local job, simply click "View Jobs" or use the Search Box to narrow your Spokane Help Wanted Ads search by job title, skills, company and/or location. Employers: To post a Spokane Help Wanted Ad, simply click on "Post a Job" and follow the user friendly form. If you have any questions, please contact us and we will be glad to help.


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automatic cars in india under 5 lakhs
Did you mean?
- Top 10 Utility Cars in India Under 5 lakhs
- Top 10 Small Cars in India Under 5 lakhs
- Top 10 Midsize Cars in India Under 5 lakhs
- Top 10 Luxury Cars in India Under 5 lakhs
- Hyosung GV650 cruiser bike price in India to be under Rs.5 lakh
- Volvo V40 Cross Country confirmed for India. To be priced under Rs.30 lakhs!
New Cars
Mercedes Benz CL Class
Mercedes Benz CL Class is a Sedan car which is powered by a 5461 CC engine. The car has a Automatic type of transmission/gearbox. The car runs on Petrol and sports a mileage of 0.0 Km/L. The dimensions of Mercedes Benz CL Class are 5065X1871X1419 mm (length X width X height). Mercedes Benz CL Class is priced at Rs. 1,19,74,861 (ex-showroom, New Delhi). ... read more
BMW 5 Series GT
The BMW 5 series GT is an unconventional take on a 5 series for those who want more legroom and headroom and comfort. In India it has been a hit and has done well. The front end of the GT is a combination of the imposing snout like that of the X family (though a slightly toned down version of it) an ... read more
Used Cars
Tata Safari 4X2 EX DiCOR BS-IV (2011)
For Sale April 2011Tata Safari Ex BSIV in Excellent Condition. Done only 27000 kms. Main features: 1. Excellent condition, only 28000 kilometers. 2. Extended Warranty until April 2015 3. One Free Service Remaining Under AMC. 4. Insurance until April 2015 5. Second owner (but the car is in pristine condition) 6. Reason to Sell - Need to buy an automatic. Expected price 7.0 lakhs, negotiable. ... read more
|Registration no: TN07BL3330
|Colour: White
|City: Chennai
|Asking Price: 7,00,000
Hyundai Elantra 1.6 S (2004)
Hyundai Elantra Diesel car with Karnataka registration in an excellent condition for sale !!! Hi, I am selling my December 2004 model Hyundai Elantra car with Karnataka registration in an excellent condition. The car is in excellent condition with no scratch mark or dents, original paint, entire new suspension done with 25000 KMS guarantee, all 4 new shock observer, with a new radiator and a new maintenance free battery recently fitted. The steering wheel and a gear kit is done with a wonder ... read more
|Registration no: KA 04 MC 1300
|Colour: Other
|City: Bangalore
|Asking Price: 3,75,000
Upcoming Cars
Maruti Cervo
India's leading car maker Maruti Suzuki is planning to launch more than a dozen cars in the India in the next 5 years and the Cervo is one of them. Th ... read more
Maruti Swift Sport
In India the hot hatch segment started with the Palio 1.6. It was a starting of a new revolution, however these days the hot hatch is limited to one o ... read more
User Reviews
Hyundai Santro Xing Reviews
overall for our Country like india it schould give more mileage, and also cost normaly. Automatik takes around 5 to 6 km per liter . In europe take a VW Fox or polo or Toyota thez are consumer friendly. Not like this Bloody Korean make . Dont buz never thsi is not a car this is a catastrophe. read more
Maruti 800 Reviews
Exterior Maruti 800, that actually looks big. Best styling that you can get in under Rs.3 Lakh Rupees. Interior (Features, Space & Comfort) It has more space than EON, Spark, Nano at competitive prices (Nano is cheaper but its auto rickshaw with 4 wheels). In 3 Lakhs this Maruti 800 offers the bread more
Well, how about a Volvo V40 Cross Country for under Rs.30 lakhs? If that doesn't set your pulse racing, then you should probably head to your physic Read more detail
Korean bike maker Hyosung alongwith their Indian arm at DSK Motors are all set to launch a new product among their existing portfolio of three bikes Read more detail
Expert Reviews
Honda Brio Petrol versus Toyota Etios Liva Petrol
Honda Brio is Honda's first car in the sub 5 lakhs rupee price bracket in India and a very important car in the market segment for Honda. The Japanese read more
Datsun Go Test Drive & Review in India
Introduction: India is home to the 2nd largest passenger car market in the world and the entry level small hatchback segment alone, under Rs 4 read more
Mercedes GL Class India Review, GAADI.COM
The Mercedes GL is probably the best real SUV under a crore in India. What makes it so special? We find out.. ...view video
Audi S6 India Launch, Turbo 49
Audi India, launched Audi S6 in India, with starting price of 85.99 Lakhs. The Audi S6 is the more powerful version of the sedan A6 and has a powerful ...view video
Forum Discussions
Hydrogen Booster
Hello. Anybody tried adding hydrogen booster in cars? in India
I want to buy a new sedan type car below 6 lakhs
Hi! I am planning to buy a new sedan type car my budget is not more than 6 lakhs. This is first time I am buying a car in India. Before this I only owned automatic cars. Among available lot I i
New Car Dealers
Kairali Ford ( Ford)
Kerala Cars Pvt Ltd, Mea Junction, Chenkotta Road, Kareekode, Kollam, Kerala, Pin: 691005, India, Kareekode
Phone: 0474 - 2711314
Ncr Ford ( Ford)
14 / 5, Main Mathura Road, Faridabad Haryana 121003, India, Main Mathura Road
Phone: 0129-4015531
Used Car Dealers
Cars India Pvt. Ltd.
Cars India Pvt Ltd. ,No. 87, Arcot Road, Saligramam, ChennaiChennai
Vishal Motors
5/149, Shobha Bldg., M.p.road, Wadala, Mumbai, 400031, Maharashtra, IndiaMumbai
Mobile: 0-9820055912


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FAB Concerts for Kids
Putnam Triangle Plaza
Until Fri Sep 27 2013
- Free
Photograph: Courtesy FAB Alliance
Not yet rated
Time Out says
Thu Apr 19 2012
Once a month during the spring and summer, FAB Alliance hosts live outdoor concerts for tots, plus crafts and activities. This year's series kicks off with singer-songwriter and music therapist Jon Samson (Apr 26), followed by Brooklyn-based kindie rockers Rolie Polie Guacamole (May 31). The lineup continues into the summer with Roderick Jackson and Palms Down Percussion Ensemble (June 28), Lou Gallo (July 26), the Good Ms. Padgett (Aug 23) and the Rozz and Val Show (Sep 27). Ages 18 months to 8 years.
CommentsAdd +
Venue details
Putnam Triangle Plaza Fulton St
Clinton Hill
- Cross Street:
between Cambridge Pl and Grand Ave
- Transport:
Subway: C to Clinton-Washington Aves
Putnam Triangle Plaza
- Fulton St
Clinton Hill
- 40.687119,-73.975375
- Fulton St
- Putnam Triangle Plaza
- Event website:
- Categories:
Things to Do
- Good for:
Celebrations. Going in a group. Mood. Energetic and active. Outdoor activities. Quirky. Kids. Hands-on for kids. Play with other kids
- Event type:
Concerts. Festivals. Performances
- Date Time Price information
Fri Aug 23 201310:00am


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Anthony Ha
Anthony Ha is a writer at TechCrunch, where he covers media and advertising. Previously, he worked as a tech writer at Adweek, a senior editor at the tech blog VentureBeat, and a local government reporter at the Hollister Free Lance, where he won awards from the California Newspaper Publishers Association for breaking news coverage and writing. He attended Stanford University and now lives in Brooklyn.
Disclosure: I own shares in VentureBeat.CrunchBase profile →
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It looks like there are some big challenges ahead for mobile advertising, as the industry faces increasing scrutiny from the federal regulators, and as Apple phases out the UDIDs used by advertisers and publishers to identify users. Now privacy company TRUSTe is offering a new way for advertisers to address some of these concerns. The program is called TRUSTe Mobile Ads, and it allows consumers… Read More
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Rumblefish, a service where consumers and businesses can easily license music for their online videos, says that its catalog now has more than 1 million songs, making it the largest licensing catalog of pre-cleared music. The idea is pretty simple: When you're posting a video on a site like YouTube, you might want to flesh it out by adding a soundtrack. However, most people don't… Read More
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An online journal about visual art, the urban landscape and design. Mary Louise Schumacher, the Journal Sentinel's art and architecture critic, leads the discussion and a community of writers contribute to the dialogue.
REVIEW: Frank Lloyd Wright at the Milwaukee Art Museum
We remember Frank Lloyd Wright mostly for his inventive structures, the curvy bands of the Guggenheim set defiantly into Manhattan's hard-edged grid or his revolutionary "prairie houses" tucked into Midwestern slopes and valleys like Japanese hair combs.
We know him, too, for his imperious swagger, his scandalous affairs and those infamous leaky roofs. »Read Full Blog Post
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did he build anything that didn't leak?
XE6JOO Awesome article.Really looking forward to read more. Will read on...
PpHaSA Thanks a lot for the article post.Thanks Again. Want more.
rbBTXl Appreciate you sharing, great post.Really looking forward to read more. Really Cool.
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New York Giants Win Super Bowl XLVI
The New York Giants win the Super Bowl, beating the New England Patriots 21-17.
Use our new superlist posting interface and quickly create exceptional, media-rich buzz posts.
The New York Giants win the Super Bowl, beating the New England Patriots 21-17.
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UPDATE: A statement was released by the Paterno family Sunday morning to announce the former Penn State coach lost his battle with lung cancer. He was 85.
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The former Penn State coach's health has taken a turn for the worse after minor complications from cancer treatments have turned more serious. Earlier reports that Paterno died were incorrect.
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BuzzFeed Breaking News is a BuzzFeed user and their posts have not been vetted or endorsed by BuzzFeed's editorial staff. BuzzFeed Community is a place where anyone can post awesome lists and creations. Learn more or post your buzz!


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Apr 16, 2011 at 11:37AM EDT
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An old doodle, becoming in cloth.
Going to take a few days off to welcome September.... see you later.
in doodle wednesday, hearts, skitch skatch | Permalink
Comments (31)
I was at Mom's yesterday. She needs someone there most of the time now. Although my brother helps a lot, my days are way too full. My back hurts. The house is a mess. I am scattered. Sometimes just putting a few scraps together makes me feel more together. I enjoy the sense that all those little separate bits are still one somehow. That pieces of a story that fell apart can be put back together in some useful way. The sun rose warm like a promise this morning. The view is more open through the storm thinned trees. It is almost like some trees fell down to give me a sense of space and a better view of the old sea. I suppose any change is a gift of new vision. It is a December walking day. Now where did I put my shoes?
in Cloth is like self, hearts, life, little things, mending, mom, old sea, One-ness, problem solving, scraps of self, season, seeing through things, skitch skatch, space, walking, whispering hearts, winter | Permalink
Comments (30)
I'm still going.
And experimenting with mobile blogging.
If you signed up for Spirit Cloth 101, the welcome email will go out tomorrow evening (New York time, about 24 hours from now). Please check your PayPal email if you have not given me an alternative contact. And check your spam folder. Please email me if you do not get the welcome note. Class begins on the 15th. Thanks, see you later.
in continuing aka Just Going, design planning, life, lions, moons, natural order, patchwork, place, quilt stories, self portrait, skitch skatch, small journeys, space, story fragments, the beast, trust, wandering | Permalink
Comments (37)


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Tell a friend
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Alexander McQueen
Ruffle crepe top (212635)
Style notes
Alexander McQueen takes separates into evening with this waist-cinching black top. It's crafted from black crepe and has a ruffle front feature along with a flattering peplum hem. Work a chic monochrome look and team it with sleek white trousers and black pumps.Shown here with Alexander McQueen Book studded leather box clutch, Alexander McQueen Crystal-embellished flower ring and Sergio Rossi Blink suede pumps.
- Black, crepe
- Round neck, short sleeves
- Ruffle front and peplum
- Centre-back concealed zip fastening
- 59% rayon, 41% acetate. Lining: 75% rayon, 25% silk.
- Dry clean
- Country of origin: Italy
Size and fit
View this item's measurements Size Guide
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- Model is 5ft 9in/ 1.75m, is a size UK08 and wears a size 40IT (US04/ 36FR/ UK08). Please refer to size guide for further help
- Shoulder to hem 24in/61cm
- Bust 33in/84cm
- Waist 28in/71cm
- Sleeve length 7.5in/19cm
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event date: July 12 -13, 2014
Application Deadline for Food Vendors: April 30, 2014
Application Deadline for Non-Profits: April 30, 2014
Art in the Park is free to the public and features nearly 150 artist vendors, live entertainment, food vendors, and an interactive children's art area. This popular and successful event takes place on July 12th and 13th over Rainbow Weekend, which combines with the Pro Rodeo and the Balloon Rodeo to produce a weekend of fun and excitement. Around 10,000 people attend the festival located in West Lincoln Park, on the west end of downtown Steamboat Springs.
Art in the Park Application Deadline Approaching
Posted in Uncategorized


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Subtraction Number Crunching #1
Bite into math with this worksheet packed with two-digit subtraction practice. Kids are sure to beef up their subtraction facts fluency and mental math skills as they complete this printable. Watch out—these problems require borrowing!
Ready for more number crunching? Check out the entire series here.
Topics: Second Grade, Subtraction
Updated on May 27, 2010
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Not too long ago, "Adventure Time" was a quirky program on Cartoon Network with a steady cult following. Now in its fifth season, the animated effort based on a 2008 short by creator Pendleton Ward -- in which adolescent Finn and his talking dog pal Jake going on fantastical trips through the bizarr...Read More »
Having been responsible for several of the highest-rated episodes of the extraordinarily successful Cartoon Network series "Adventure Time" (those featuring Fionna and Cake, the gender-bent versions of main characters Finn and Jake), artist Natasha Allegri has joined Frederator Studios to create her...Read More »
The Creative Arts Emmy ceremony will take place on September 15 at the Nokia Theatre, with a two-hour edited version being broadcast on the 21st on the new FX spin-off network FXX -- but these folks below already know they're going home with an award.Read More »
Adventure Time is one of those properties that taps right into what its audience is looking for at just the right time. Though there is undoubtedly an adult crossover – and certainly a college student following – Adventure Time nails what I would surmise is its target: children and adolescents.Read More »
We held our first contest today. The contest is now closed - but check out what we gave away.Read More »
Far and away the hottest cartoon on TV right now. Is Adventure Time as the start of a great era, or the pinnacle of one?Read More »
Check this out. The cover of Abrams official guide to the hit series Adventure Time, coming out on August 6th. "Translated from the scrolls of Ooo" by my ol' buddy Martin Olson (comedy guru and scripter of Phineas and Ferb and Rocko's Modern Life), the book is a celebration of all things "Algebraic"...Read More »
Sometimes you love a show so much it can do weird things to your head. I've gone out on a limb with Cartoon Network's "Adventure Time" by deeming it a groundbreaking form of cartoon storytelling that fuses several eras of animation into a delightfully surreal and yet oddly familiar experience.Read More »
Sure, Sunday tends to be overcrowded with high-end TV, including "Shameless," "Californication," "The Walking Dead" and the back-this-week "Game of Thrones," but what to watch the rest of the time? Every Monday, we bring you five noteworthy highlights from the other six days of the week.Read More »
Watching last night's anthology episode of "Adventure Time," entitled "Five More Short Graybles," I was reminded of the crazed photographer in Leos Carax's "Holy Motors" when he first spots the scraggly-haired Merde character, played by Denis Lavant, in the...Read More »


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Aug 01st 2014
Sapphire Now Shines in Boca
NY/NJ restaurateur Raju Brahmbhatt opens upscale Indian eatery. Read More
Jul 31st 2014
The Truth About Zinburger
Zinburger's burger-and-wine concept takes the cake ... or the pie. Read More
Jul 30th 2014
Chia Seeds vs. Flax Seeds
Green Goddess: Are chia or flax seeds better? Read More
Jul 28th 2014
Grease to Grace the Travel Channel
West Palm burger joint to be featured on "Hamburger Paradise 3." Read More
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Small Bites: Chowder & Sammies in WPB
Chowder Heads coming, 100 Montaditos finally here. Read More
Jul 23rd 2014
Paradise Found: Happy Hour at Tanzy
You can count on the staff of Boca Raton magazine to take care of you in your hour of need. Read More


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1. Plan all my meals for seven days
2. Eat what I have planned
Keep up the good work with the exercise
I really enjoyed my weekend away. It was
I even won a few pounds on the first race!
But now it's back to business! Only six weeks to lose 10lbs.
I'm so excited. I'm off to the races with my friends this weekend.
I'm not sure what I'm going to eat. I am going to try to eat soup to balance out the other calories I'll be consuming. Hope that goes well!
I've decided to find out what motivates me.
What's drives you forward? What inspires you to reach your goal?
I have just been reading an article in a magazine that I bought and it was talking about what drives you to lose weight. The 'carrot' part of the article was a bit lacking!
The thing driving me forward is being able to wear the clothes I want and to look good in them.
Being able to do ballet (which is hard on your knees at the best of times, but with 50lbs extra on your knees oh boy!!!)
Being healthy is a big factor for me as well.
My sticks?
Well - I hate clothes shopping, looking in those mirrors in the dressing room! Thinking to yourself did I really come out looking like this! Maybe that's just me!
I'm in my thirties and my knees crack (not good!)
Then there is the if you're fat you're going to get just about every disease known to mankind (at least it feels like that when you read the papers / watch the news.
Wondering 'would I have a partner if I were slimmer'! That's a big one for me.
If you have any good carrots or sticks let me know.
I'm getting better at all of this.
I'm really pleased with my exercise minutes.
I've reduced my calorie intake.
I'm really beginning to enjoy the benefits of drinking 8 glasses of water everyday (I've gained about 3 hours a day because I don't feel as tired)
My skin looks much better.
Next step - plan meals for the week so I hit all my nutritional goals!
I'm really excited about the week ahead.


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DIA's Content Currents provides you with new and important global regulatory developments and their impact on pharmaceutical, biotechnology, and medical product development.
EDITION PUBLISHED: December 5, 2014
CDER List of Guidance Documents (Updated)
CDER Guidances New/Revised/Withdrawn 1/1/14 - 9/30/14
The links above lead to the List of Guidance Documents (CDER) updated on October 27, 2014, and to CDER Guidances that are new, revised, or withdrawn through the third calendar quarter of 2014.
On December 5, 2014, FDA announced the availability of a draft guidance entitled "How To Obtain a Letter From the Food and Drug Administration Stating That Bioequivalence Study Protocols Contain Safety Protections Comparable to Applicable Risk Evaluation and Mitigation Strategies for Reference Listed Drugs." This draft guidance describes how a prospective abbreviated new drug application (ANDA) applicant may request a letter stating that FDA has determined the following: The potential applicant's bioequivalence (BE) study protocol contains safety protections comparable to those in the risk evaluation and mitigation strategy (REMS) with elements to assure safe use (ETASU) applicable to the reference listed drug (RLD) and FDA will not consider it a violation of the REMS for the RLD sponsor to provide a sufficient quantity of the RLD to the interested generic firm or its agent to allow the firm to perform the testing necessary to support its ANDA. Comments should be submitted by February 3, 2015. [Federal Register]
On December 4, 2014, FDA announced the availability of the final rule entitled ''Content and Format of Labeling for Human Prescription Drug and Biological Products; Requirements for Pregnancy and Lactation Labeling." FDA is amending its regulations governing the content and format of the ''Pregnancy,'' ''Labor and delivery,'' and ''Nursing mothers'' subsections of the ''Use in Specific Populations'' section (under § 201.57 (21 CFR 201.57)) and the ''Precautions'' section (under § 201.80 (21 CFR 201.80)) of the labeling for human prescription drug and biological products (both referred to as ''drugs'' or ''drug products'' in this final rule). In this rulemaking, the Agency is finalizing many of the provisions in the proposed rule issued on May 29, 2008 (73 FR 30831). This rulemaking is part of a broad effort by the Agency to improve the content and format of prescription drug labeling. The final rule creates a consistent format for providing information about the risks and benefits of drug use during pregnancy and lactation and by females and males of reproductive potential. [Federal Register]
On December 4, 2014, FDA announced the availability of a draft guidance entitled ''Pregnancy, Lactation, and Reproductive Potential: Labeling for Human Prescription Drug and Biological Products—Content and Format." This draft guidance is intended to assist applicants in complying with the new content and format requirements in the Pregnancy, Lactation, and Females and Males of Reproductive Potential subsections of labeling for human prescription drug and biological products, as described in the final rule, Content and Format of Labeling for Human Prescription Drug and Biological Products; Requirements for Pregnancy and Lactation Labeling. The rule, which is being published concurrently with this draft guidance, is referred to as the ''Pregnancy and Lactation Labeling Rule'' (PLLR). The draft guidance will assist applicants in developing labeling for new products, revising existing labeling, and implementing the content and format requirements of the PLLR for human prescription drug and biological products. Comments should be submitted by February 2, 2015. [Federal Register]
On December 2, 2014, FDA announced the availability of the guidance entitled ''Recommendations for Labeling Medical Products To Inform Users That the Product or Product Container Is Not Made With Natural Rubber Latex." The purpose of this guidance is to make recommendations on the appropriate language to include in the labeling of a medical product to convey that natural rubber latex was not used as a material in the manufacture of the product, product container, and/or packaging. FDA is concerned that statements submitted for inclusion in medical product labeling, such as ''latex-free,'' ''does not contain natural rubber latex,'' or ''does not contain latex'' are not accurate because it is not possible to reliably assure that there is a complete absence of the allergens associated with hypersensitivity reactions to natural rubber latex in the medical product. [Federal Register]
On December 2, 2014, FDA announced the availability of a scale-up and post-approval changes guidance entitled ''SUPAC: Manufacturing Equipment Addendum." This replaces the draft guidance of the same name that combined and superseded ''SUPAC IR/MR: Immediate Release and Modified Release Solid Oral Dosage Forms: Manufacturing Equipment Addendum,'' published on January 1, 1999; and ''SUPAC–SS: Nonsterile Semisolid Dosage Forms; Manufacturing Equipment Addendum,'' published as a draft on December 1, 1998. FDA revised the draft manufacturing equipment addenda to remove the equipment examples and to clarify the types of processes being referenced. [Federal Register]
On December 1, 2014, FDA announced the submission to OMB of a proposed collection of information on a ''Medical Devices; Humanitarian Use Devices." This collection of information implements the Humanitarian Use Devices (HUD) provision of section 520(m) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act) (21 U.S.C. 360j(m)) and subpart H, part 814 (21 CFR part 814). The information collected will assist FDA in making determinations on the following: (1) Whether to grant HUD designation of a medical device; (2) exempt an HUD from the effectiveness requirements under sections 514 and 515 of the FD&C Act, provided that the device meets requirements set forth under section 520(m) of the FD&C Act; and (3) whether to grant marketing approval(s) for the HUD. Comments should be received by December 31, 2014. [Federal Register]
On November 28, 2014, FDA announced announced the availability of a draft guidance entitled "Recommended Warning for Over-the-Counter Acetaminophen-Containing Drug Products and Labeling Statements Regarding Serious Skin Reactions." The draft guidance is intended to inform manufacturers, members of the medical and scientific community, and other interested persons that at this time we do not intend to object to the marketing of single- and combination-ingredient, acetaminophen-containing, nonprescription (commonly referred to as over-the-counter (OTC)) drug products bearing a warning as described in the draft guidance alerting consumers that the use of acetaminophen may cause severe skin reactions. Comments should be submitted by January 27, 2015. [Federal Register]
On November 28, 2014, FDA announced announced the availability of a draft guidance entitled "The Drug Supply Chain Security Act Standards for the Interoperable Exchange of Information for Tracing of Certain Human, Finished, Prescription Drugs: How To Exchange Product Tracing Information." The draft guidance addresses the drug supply chain security provisions of the Federal Food, Drug, and Cosmetic Act (the FD&C Act), which requires the Secretary of the Department of Health and Human Services to establish initial standards for the interoperable exchange of transaction information, transaction history, and transaction statements, in paper or electronic format. Specifically, the guidance establishes standards for how transaction information, transaction history, and transaction statements should be exchanged among trading partners through the extension and/or use of current systems and processes. Comments should be submitted by January 27, 2015. [Federal Register]
On November 24, 2014, FDA announced the availability for public comment of ''Demographic Subgroup Data for FDA Approved Products on FDA's Internet Website.'' This new posting implements Action 3.1 from Priority 3 of the Food and Drug Administration Safety and Innovation Act (FDASIA) Section 907 Action Plan designed to improve the availability and transparency of clinical trial demographic subgroup data. FDA is requesting comments on the format, content, and overall usability of the site to determine whether this approach is user friendly to the public. Comments should be submitted by January 23, 2015. [Federal Register]
On November 24, 2014, FDA announced announced the availability of a final guidance entitled "Registration of Human Drug Compounding Outsourcing Facilities Under Section 503B of the FD&C Act." The guidance is intended to assist human drug compounders that elect to register as outsourcing facilities in registering, re-registering, or de-registering with FDA. The guidance provides information on how an outsourcing facility should submit facility registration information electronically in structured product labeling (SPL) format using FDA's electronic submission system. [Federal Register]
On November 24, 2014, FDA announced announced the availability of a final guidance entitled "Fees for Human Drug Compounding Outsourcing Facilities Under the FD&C Act." This guidance describes the annual establishment fee, the reinspection fee, annual adjustments to fees required by law, how to submit payment, the effect of failure to pay fees, and how to qualify as a small business to obtain a reduction of the annual establishment fee. [Federal Register]
On November 24, 2014, FDA announced announced the availability of a revised draft guidance entitled "Electronic Product Reporting for Human Drug Compounding Outsourcing Facilities." The revised draft guidance addresses provisions in the Federal Food, Drug, and Cosmetic Act (the FD&C Act) added by the Drug Quality and Security Act (DQSA) and updates reporting instructions for drug compounders that choose to register as outsourcing facilities. Comments should be submitted by January 23, 2015. [Federal Register]
On November 24, 2014, FDA announced announced the availability of a guidance entitled "Design Considerations for Devices Intended for Home Use." This document supersedes "Design Considerations for Devices Intended for Home Use" issued August 5, 2014. Devices used in the home or other non-clinical environments are associated with unique risks created by the interactions among the user (often a layperson), the use environment, and the device. This guidance identifies several factors that manufacturers of home use devices should consider, especially during device design and development, and provides recommendations for minimizing these unique risks. [Federal Register]
FDA still may not be able to clearly describe the bar for a breakthrough therapy, but an internal analysis indicates the agency is building evidence toward a more clear description of the criteria for potential sponsors.
An FDA evaluation of the first two years of the program indicates some similar characteristics of products receiving breakthrough status as compared to products that didn't. The biggest factor in breakthrough designation decisions may be the magnitude of treatment effect. Dr. Janet Woodcock, CDER Director, indicated that designees have clinical data showing a more than 50% risk reduction, such as in disease progression, over the comparator. Breakthrough success did not appear affected by orphan drug status, but targeted therapies or those with a genetic component were more likely to gain the designation. More designees in the FDA analysis had alternative therapies available than denials. Breakthrough designees also tended to have evidence from more trials and a slightly higher trial enrollment.
FDA consulted a Morquio A patient and several caregivers as it struggled to determine the clinical relevance of the candidate product's effect on the six-minute walk test, apparently unbeknownst to the product's sponsor.
Early in the review, the agency conducted a teleconference with "patient caregivers and an adult patient" to better understand their personal experiences, according to the clinical review document. The meeting occurred less than two months after the application had been filed. No minutes of the meeting were included in the publicly available review documents, but a footnote in advisory committee briefing documents says that patients shared the "clinical signs and symptoms that are most troublesome." An FDA statement indicated that "reviews often incorporate the patient perspective at varying levels of interactions and phase of drug development."
More at link above. (The Pink Sheet, paid subscription required)
"Today, after years of careful consideration — and listening to public feedback — FDA has published a final rule that sets standards for providing a consistent way for drug manufacturers to provide information about the risks and benefits of prescription drug and biological products used during pregnancy and lactation. It also includes requirements for ways of communicating relevant information for women and men of reproductive potential.
"Here's a quick overview: Prescribing information for health care professionals provided by manufacturers will now contain required subheadings within the Pregnancy and Lactation subsections: risk summary, clinical considerations, and data. These subsections will provide more detailed information regarding, for example, human and animal data on the use of the drug, specific adverse reactions and information about dose adjustments needed during the pregnancy and post-partum (after giving birth) periods. It will apply not just to new drugs approved from now on, but also to older drugs approved since 2001 that have been marketed for years without their labeling being updated to incorporate important new information related to pregnancy and lactation."
Patient-Focused Drug Development: Disease Area Meetings Planned for FY2013-2015
Meeting. Realizing the Benefits of the Unique Device Identifier in Health Care. Office of the National Coordinator and Pew Charitable Trusts. December 9, 2014. Washington, DC. This meeting will present discussion on the benefits and challenges of integrating the unique device identifiers (UDI) into clinical care, registries, the supply chain, and other facets of health care delivery. [FDA.gov]
Public Workshop. Developing and Using Precision Therapies in the ''Omics'' Era: Generating and Interpreting Evidence for Rare Subsets. December 12, 2014. White Oak Campus, Silver Spring, MD. Cosponsored with the Center for Translational and Regulatory Sciences at the University of Virginia (UVA). The goals of this public workshop are to facilitate discussion on current scientific approaches using rare subsets during drug development programs and to further seek input from multiple stakeholders on approaches to obtain evidence that inform the regulatory evaluation of therapeutic products in rare subsets of patients identified through in-vitro diagnostic testing when specific, controlled trials are not feasible. [Federal Register]
Public Workshop. Immunology of Protection from Ebola Virus Infection. December 12, 2014. Rockville, MD and Webcast. The Food and Drug Administration (FDA), the National Institutes of Allergy and Infectious Diseases (NIAID), the Department of Defense (DoD), the Centers for Disease Control and Prevention (CDC), and the Biomedical Advanced Research and Development Authority (BARDA) are co-sponsoring a workshop, entitled "Immunology of Protection from Ebola Virus Infection." The purpose of this workshop is to discuss important aspects of Ebola virus and vaccine immunology in order to inform future clinical, scientific and regulatory decision-making related to vaccines against Ebola. [FDA.gov]
January 8-9, 2015. Two-day public meeting on prioritization of Lab-Developted Tests (LDTs). At this meeting, FDA will discuss its proposal for a risk-based framework to address regulatory oversight of laboratory developed tests (LDTs). The agency plans to discuss with stakeholders how to balance patient safety and access to LDTs.. (FDA.gov)
Public Policy Committee Meeting. Health Information Technology Policy Committee Advisory Meeting. Monthly beginning January 13, 2015. Locations to be published. This notice announces forthcoming meetings of a public advisory committee of the Office of the National Coordinator for Health Information Technology (ONC). The function of the committee is to provide recommendations to the National Coordinator on a policy framework for the development and adoption of a nationwide health information technology infrastructure that permits the electronic exchange and use of health information as is consistent with the Federal Health IT Strategic Plan and that includes recommendations on the areas in which standards, implementation specifications, and certification criteria are needed. [Federal Register]
Public Standards Committee Meeting. Health Information Technology Standards Committee Advisory Meeting. Monthly beginning January 28, 2015. Locations to be published. This notice announces forthcoming meetings of a public advisory committee of the Office of the National Coordinator for Health Information Technology (ONC). The function of the committee is to provide recommendations to the National Coordinator on standards, implementation specifications, and certification criteria for the electronic exchange and use of health information for purposes of adoption, consistent with the implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the Health IT Policy Committee. [Federal Register]
Public Workshop. Seventh Annual Sentinel Initiative. February 5, 2015. Washington, DC. Convened by the Engelberg Center for Health Care Reform at the Brookings Institution and supported by a cooperative agreement with FDA, this 1-day workshop will bring the stakeholder community together to discuss a variety of topics on active medical product surveillance. There will also be a live webcast for those unable to attend the meeting in person. [Federal Register]
Public Meeting. Chagas Disease Patient-Focused Drug Development. April 28, 2015. White Oak Campus, Silver Spring, MD. FDA is interested in obtaining patient input on the impact of chagas disease on daily life and patients' views on currently available therapies to treat the condition. [FDA.gov]
"As obstetrician-gynecologists, we understand the importance of keeping women healthy before, during, and after their pregnancies, whether they live with chronic conditions or whether they are confronting new diagnoses. And, we recognize that medications can be vital to maintaining a mother's continued good health when pregnant, a goal of central concern in obstetric care. It is essential that all providers have the information they need to safely, effectively, and reliably treat their female patients. We also want to ensure that medicines will help, and not harm, both mother and child.
The draft NIH policy proposes that all NIH-funded, multi-site studies carried out in the United States, whether supported through grants, contracts, or the NIH intramural program, should use a single IRB. Exceptions to the policy would be allowed if local IRB review is necessary to meet the needs of specific populations or where it is required by federal, state or tribal laws or regulations. Wider use of single IRB review in multi-site studies will help achieve greater efficiencies in the initiation of studies across NIH's entire clinical research portfolio.
"PCORI recently convened a large stakeholder workshop to discuss whether new comparative clinical effectiveness research (CER) studies we might fund could answer key questions about how to best diagnose and treat hepatitis C (HCV) infection. It was a particularly timely event given recent regulatory approvals of groundbreaking new treatments for this serious condition. I summarized the workshop event in an earlier blog post and now want to update you on our next steps.
CMS attributed the slowdown partly to meager growth in Medicare and private health insurance spending. Medicare growth dipped to 3.4% in 2013 from 4% in 2012, and was affected by slower enrollment, some ACA provisions and federal budget sequestration. Out-of-pocket costs and spending on hospital, physician and clinical services also decelerated in 2013.
Prescription drug spending grew at a rate of 2.5% in 2013, up from 0.5% in 2012, amid price increases for brand name and specialty drugs, higher spending on new drugs and more total prescriptions. Several blockbuster drugs lost patent protection in 2012.
EMA Management Board discusses next steps after judgment of EU Civil Service Tribunal
The Management Board chaired by Sir Kent Woods confirmed that Deputy Executive Director Andreas Pott will be in charge of the management and operations of the Agency until the new selection procedure suggested by the European Commission is finalised. The European Commission plans to publish a vacancy announcement for the post of Executive Director shortly.
The researchers claim to have evidence of a "team of native-English speaking operators with extensive knowledge of the nuances in industries they targeted as well as financial practices".
H.R. 669, introduced by Health Subcommittee Ranking Member Frank Pallone (D-NJ) and Rep. Peter King (R-NY), provides for activities to help improve the understanding of stillbirth, sudden unexpected infant death, and sudden unexplained death in children.
S. 2917, championed by full committee Vice Chairman Marsha Blackburn (R-TN) in the House, will strengthen the Food and Drug Administration's voucher program to include diseases like Ebola. This will help encourage more investment and innovation for the development of treatments for these diseases. Blackburn commented, "With nearly 15,000 cases and over 5,000 deaths, the 2014 Ebola epidemic is the worst since the discovery of the virus in 1976. In light of this global outbreak there should be an intensive effort to find and approve a treatment or better yet, a vaccine to prevent Ebola."
A complete list of the committee's bipartisan #RecordOfSuccess is available online here. More at link above. (Energy and Commerce Release)
A partial listing of sources reviewed for this newsletter: AdvaMed Smartbrief; AHRQ Newsletter; Alzheimers Association; Alzheimers Research Forum Newsletter; BioCentury; Biopharma Reporter; BIOtechNow; CDISC Monthly Newsletter; CER Daily Newsfeed (NPC); Daily Dose (Becker); DIA Daily; Drug Daily Bulletin; EMA website; EP Vantage; Evaluate Pharma; Eye on FDA; FDA.gov; FDA Law Blog; Federal Register Table of Contents; Fierce Medical Devices; Fierce Pharma; Fierce Vaccines; FDLI Smartbrief; Genomeweb; Health Industry Washington Watch; Government Health IT; Health IT Security; Institute of Medicine News; MedCityNews; Medical Device Daily; Medical Device & Diagnostic Industry; MedPage Today; NPC Bulletin; Nutra Ingredients USA; Pharmabiz; Pharmafile; Pharma IQ; PharmaTimes; PhRMA website; PM Live; Policy and Medicine (newsletter); Regulatory Focus; RegLink News; US FDA Daily Digest Bulletin.


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INGREDIENTS: (Mac and Cheese)
6 Cups Water
1 box pasta
Pinch of salt
1 stick butter
6 Tbls flour
3 Cups milk
1 Cup heavy cream
4 Cups Cheddar (1 lb)
2/3 Cup other mild cheese (Asiago, gorgonzola or swiss)
1 and 1/2 Cup sharp cheese (Parmesan, Romano, Duldiner, Ale House Cheddar)
1 Tbls pepper
1 tsp nutmeg
1 tsp cayenne
2 Cups bread or cracker crumbs
Put water and salt in pot and bring to a boil over medium heat. Add pasta and cook until al dente.
In a large saucepan, melt butter and slowly sprinkle in flour and cook on medium high heat until thick.
Add milk and whisk until thick.
When bubbles appear in mixture, add in heavy cream and cheeses. Cook until cheeses are melted.
Add seasonings and mix.
Add 2/3 of the cooked pasta into the sauce and mix.
Place in baking dish – sprinkle bread crumbs on top and bake at 350 for 20 minutes.
INGREDIENTS: (sliders)
1 package mini egg twists (or any small bun)
slices of honeybaked Ham or Turkey
Swiss Cheese
1 Tbls Hickory Honey Mustard
1 Tbls Savory Mayonnaise
Make as usual sandwiches. If you want them toasted… place sliders on cookie sheet and bake in oven for 10 minutes at 350 degrees.
Honeybaked Ham Co.
2770 McKenzie St.
Foley, AL 36535
The Squashed Grape
2770 McKenzie St.
Foley, AL 36535
About the Guest:
Marissa Wilkins is the owner of The Squashed Grape. She just recently graduated from Auburn University with studies in Literature, Italian and Political Science. Marissa studied wine in Taormina, Sicily before opening the Squashed Grape in September of 2013.


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Region 1 seeks athletic director for high school
FALLS VILLAGE — With the departure of Dan Carroll, athletic director at Housatonic Valley Regional High School, a search committee has been formed to find his replacement.
Anne MacNeil, the school's athletic trainer, is serving as the interim.
Read more of this story and more!
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The 5 Grimiest Shots Aimed At Hip-Hop Baby Mommas
50 Cent vs. Rick Ross, Tia and Brooke
During his assault to destroy Rick Ross' reputation, 50 Cent released scathing videos about two of Ross' childrens' mothers. First, she interviewed "Tia," who verified that Ross was a correctional officer and accused him of being deadbeat dad. He then hilariously took her and her friend shopping for fur coats and jewelry, as Stevie Wonder's "Isn't She Lovely" played. Then, he released a porno tape of Brooke, Ross' other baby's mother, while narrating the video as Pimpin' Curly, a comical character he created for a web series. The onslaught continued with actual diss songs like "Tia Told Me." Miraculously, Ross proved that he was indeed the Teflon Don: he stuck to his guns and remained undaunted, becoming the biggest name in rap.


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Check out this Zumba Fitness Deal!
Get fit by doing a fun workout such as Zumba. Hurry because right now, for just $27 get a Zumba Fitness Core for Wii or Kinect for Xbox 360 ($39.99 List Price)! Sculpt your core during a whole-body workout customized by level of intensity. Forty original songs or hit music from Enrique Iglesias and Karmin go with the dance-based exercises. Players can also use the game to set personal fitness goals informed by the game's free lifestyle and nutrition tips. Free shipping and free returns.
Zumba Fitness Core Features:
- Strengthens and sculpts cores during a whole-body workout
- 45 pre-set classes
- Choose from low-, medium-, or high-intensity workouts
- Personal playlists of training exercises create custom workouts
- Zumba Fitness belt, like a principal, encourages hands-free dancing
- Up to two players on the Kinect; up to four players on the Wii
- Dance to 40 original songs or hits from Enrique Iglesias and Sean Paul
- More than 30 dance styles to rhythms like Brazilian Funk and Celtic
- Learn the steps with easy-to-follow tutorials
- Exclusive Kinect features
- Full-body motion tracking for unencumbered workouts
- Class locator helps players find live Zumba classes nearby
- Voice-controlled navigation