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This is a list of publications by this organization, listed chronologically starting with the most recent first. The source of publications may be a combination of Scopus and manually entered data from a user. New publications from Scopus appear in this list weekly and publications entered by a user appear instantly. Citation counts start from 1996 and come directly from Scopus.
Sanam Loghavi; Zhuang Zuo; Farhad Ravandi; Hagop M. Kantarjian; Carlos Bueso-Ramos; Liping Zhang; Rajesh R. Singh; Keyur P. Patel; L. Jeffrey Medeiros; Francesco Stingo; et al.
Clinical features of de Novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations
Gautam Borthakur; Jorge E. Cortes; Elihu E. Estey; Elias Jabbour; Stefan Faderl; Susan O'Brien; Guillermo Garcia-Manero; Tapan Mahendra Kadia; Xuemei Wang; Keyur Patel; et al.
Gemtuzumab ozogamicin with fludarabine, cytarabine, and granulocyte colony stimulating factor (FLAG-GO) as front-line regimen in patients with core binding factor acute myelogenous leukemia
Meenakshi Mehrotra; L. Jeffrey Medeiros; Rajyalakshmi Luthra; Rachel L. Sargent; Hui Yao; Bedia A. Barkoh; Rajesh Singh; Keyur P. Patel
Identification of putative pathogenic microRNA and its downstream targets in anaplastic lymphoma kinase-negative anaplastic large cell lymphoma
C.Y. Ok; L. Li; Z.Y. Xu-Monette; C. Visco; A. Tzankov; G.C. Manyam
Erratum: Prevalence and clinical implications of epstein-barr virus infection inDeNovo diffuse large B-Cell lymphoma in Western Countries (Clin Cancer Res (2014) 20 (2338-2349))
Alberto Paniz-Mondolfi; Rajesh Singh; George Jour; Mandana Mahmoodi; A. Hafeez Diwan; Bedia A. Barkoh; Ronald Cason; Yve Huttenbach; Gustavo Benaim; John Galbincea; et al.
Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing
Zuzana Cierna; Michal Mego; Pavol Janega; Marian Karaba; Gabriel Minarik; Juraj Benca; Tatiana Sedlácková; Silvia Cingelova; Paulina Gronesova; Denisa Manasova; et al.
Matrix metalloproteinase 1 and circulating tumor cells in early breast cancer
Chi Young Ok; Zijun Y. Xu-Monette; Alexandar Tzankov; Dennis P. O'Malley; Santiago Montes-Moreno; Carlo Visco; Michael B. Møller; Karen Dybkær; Attilio Orazi; Youli Zu; et al.
Prevalence and clinical implications of cyclin D1 expression in diffuse large B-cell lymphoma (DLBCL) treated with immunochemotherapy: A report from the International DLBCL Rituximab-CHOP Consortium Program
L. Falchi; M. Mehrotra; K.J. Newberry; L.M. Lyle; G. Lu; K.P. Patel; R. Luthra; U. Popat; S. Verstovsek
ETV6-FLT3 fusion gene-positive, eosinophilia-associated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplant
Chi Young Ok; Ling Li; Zijun Y. Xu-Monette; Carlo Visco; Alexander Tzankov; Ganiraju C. Manyam; Santiago Montes-Moreno; Karen Dybaer; April Chiu; Attilio Orazi; et al.
Prevalence and clinical implications of Epstein-Barr virus infection in de Novo diffuse large B-cell lymphoma in western countries
Sa A. Wang; Robert P. Hasserjian; Patricia S. Fox; Heesun J. Rogers; Julia T. Geyer; Devon Chabot-Richards; Elizabeth Weinzierl; Joseph Hatem; Jesse Jaso; Rashmi Kanagal-Shamanna; et al.
Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms
Sanam Loghavi; Jonathan L Curry; Carlos A Torres-Cabala; Doina Ivan; Keyur P Patel; Meenakshi Mehrotra; Roland Bassett; Victor G Prieto; Michael T Tetzlaff
Melanoma arising in association with blue nevus: a clinical and pathologic study of 24 cases and comprehensive review of the literature
Manu M. Joseph; S.R. Aravind; Suraj K. George; K. Raveendran Pillai; S. Mini; T.T. Sreelekha
Antitumor activity of galactoxyloglucan-gold nanoparticles against murine ascites and solid carcinoma
Rajyalakshmi Luthra; Keyur P. Patel; Neelima G. Reddy; Varan Haghshenas; Mark J. Routbort; Michael A. Harmon; Bedia A. Barkoh; Rashmi Kanagal-Shamanna; Farhad Ravandi; Jorge E. Cortes; et al.
Next-generation sequencing-based multigene mutational screening for acute myeloid leukemia using MiSeq: Applicability for diagnostics and disease monitoring
Jesse M. Jaso; C. Cameron Yin; Victoria W. Lu; Ming Zhao; Lynne V. Abruzzo; M. James You; Yaling Yang; Raja Luthra; L. Jeffrey Medeiros; Gary Lu
B acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: A clinically aggressive subset of disease
Ohad Benjamini; Theresa Liu Dumlao; Hagop Kantarjian; Susan O'Brien; Guillermo Garcia-Manero; Stefan Faderl; Jeffrey Jorgensen; Rajyalakshmi Luthra; Rebecca Garris; Deborah Thomas; et al.
Phase II trial of HyperCVAD and Dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia
Paolo Strati; Hagop Kantarjian; Deborah Thomas; Susan O'Brien; Sergej Konoplev; Jeffrey L. Jorgensen; Raja Luthra; Lynne Abruzzo; Elias Jabbour; Alfonso Quintas-Cardama; et al.
HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia
H. Masuda; T.M. Brewer; D.D. Liu; T. Iwamoto; Y. Shen; L. Hsu; J.S. Willey; A.M. Gonzalez-Angulo; M. Chavez-MacGregor; T.M. Fouad; et al.
Long-term treatment efficacy in primary inflammatory breast cancer by hormonal receptor-and HER2-defined subtypes
F. Bertucci; N.T. Ueno; P. Finetti; P. Vermeulen; A. Lucci; F.M. Robertson; M. Marsan; T. Iwamoto; S. Krishnamurthy; H. Masuda; et al.
Gene expression profiles of inflammatory breast cancer: Correlation with response to neoadjuvant chemotherapy and metastasis-free survival
Rashmi Kanagal-Shamanna; Bryce P. Portier; Rajesh R. Singh; Mark J. Routbort; Kenneth D. Aldape; Brian A. Handal; Hamed Rahimi; Neelima G. Reddy; Bedia A. Barkoh; Bal M. Mishra; et al.
Next-generation sequencing-based multi-gene mutation profiling of solid tumors using fine needle aspiration samples: Promises and challenges for routine clinical diagnostics
M. Axelrod; Z. Ou; L.K. Brett; L. Zhang; E.R. Lopez; A.T. Tamayo; V. Gordon; R.J. Ford; M.E. Williams; L.V. Pham; et al.
Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma
Vasiliki Leventaki; John T. Manning Jr.; Rajayalakshmi Luthra; Pramod Mehta; Yasuhiro Oki; Jorge E. Romaguera; L. Jeffrey Medeiros; Francisco Vega
Indolent peripheral T-cell lymphoma involving the gastrointestinal tract
Roberto N. Miranda; Tariq N. Aladily; H. Miles Prince; Rashmi Kanagal-Shamanna; Daphne De Jong; Luis E. Fayad; Mitual B. Amin; Nisreen Haideri; Govind Bhagat; Glen S. Brooks; et al.
Breast implant-associated anaplastic large-cell lymphoma: Long-term follow-up of 60 patients
Simone Anfossi; Antonio Giordano; Hui Gao; Evan N. Cohen; Sanda Tin; Qiong Wu; Raul J. Garza; Bisrat G. Debeb; Ricardo H. Alvarez; Vicente Valero; et al.
High serum miR-19a levels are associated with inflammatory breast cancer and are predictive of favorable clinical outcome in patients with metastatic HER2+ inflammatory breast cancer
Suraj K. George; Rajesh Radhakrishnan; Sunil Kumar S.; T.T. Sreelekha; Prabha Balaram
Chemopreventive efficacy of Aegle marmelos on murine transplantable tumors
Carmen P. Escalante; Christina Meyers; James M. Reuben; Xuemei Wang; Wei Qiao; Ellen Manzullo; Ricardo H. Alvarez; Phuong Khanh Morrow; Ana M. Gonzalez-Angulo; Xin Shelley Wang; et al.
A randomized, double-blind, 2-period, placebo-controlled crossover trial of a sustained-release methylphenidate in the treatment of fatigue in cancer patients
Xin Shelley Wang; Qiuling Shi; Nina D. Shah; Cobi J. Heijnen; Evan N. Cohen; James M. Reuben; Robert Z. Orlowski; Muzaffar H. Qazilbash; Valen E. Johnson; Loretta A. Williams; et al.
Inflammatory markers and development of symptom burden in patients with multiple myeloma during autologous stem cell transplantation
Filip Janku; David S. Hong; Siqing Fu; Sarina A. Piha-Paul; Aung Naing; Gerald S. Falchook; Apostolia M. Tsimberidou; Vanda M. Stepanek; Stacy L. Moulder; J. Jack Lee; et al.
Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors
Maro Ohanian; Hagop M. Kantarjian; Alfonso Quintas-Cardama; Elias Jabbour; Lynne Abruzzo; Srdan Verstovsek; Gautam Borthakur; Farhad Ravandi; Guillermo Garcia-Manero; Richard Champlin; et al.
Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid Leukemia in accelerated phase
C. Visco; Y. Li; Z.Y. Xu-Monette; R.N. Miranda; T.M. Green; Y. Li; A. Tzankov; W. Wen; W.-M. Liu; B.S. Kahl; et al.
Erratum: Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: A report from the international DLBCL rituximab-CHOP consortium program study (Leukemia (2014) 28 (980) Doi:10.1038/leu.2014.24)
Liping Zhang; Rajesh R. Singh; Keyur P. Patel; Francesco Stingo; Mark Routbort; M. James You; Roberto N. Miranda; Guillermo Garcia-Manero; Hagop M. Kantarjian; L. Jeffrey Medeiros; et al.
BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS
Bryce P. Portier; Rashmi Kanagal-Shamanna; Rajyalakshmi Luthra; Rajesh Singh; Mark J. Routbort; Brian Handal; Neelima Reddy; Bedia A. Barkoh; Zhuang Zuo; L. Jeffrey Medeiros; et al.
Quantitative assessment of mutant allele burden in solid tumors by semiconductor-based next-generation sequencing
Preetesh Jain; Hagop Kantarjian; Keyur Patel; Stefan Faderl; Guillermo Garcia-Manero; Ohad Benjamini; Gautam Borthakur; Naveen Pemmaraju; Tapan Kadia; Naval Daver; et al.
Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse
Courtney D. Dinardo; Keyur P. Patel; Guillermo Garcia-Manero; Rajyalakshmi Luthra; Sherry Pierce; Gautam Borthakur; Elias Jabbour; Tapan Kadia; Naveen Pemmaraju; Marina Konopleva; et al.
Lack of association of IDH1, IDH2 and DNMT3A mutations with outcome in older patients with acute myeloid leukemia treated with hypomethylating agents
Amanda S. Bruegl; Bojana Djordjevic; Diana L. Urbauer; Shannon N. Westin; Pamela T. Soliman; Karen H. Lu; Rajyalakshmi Luthra; Russell R. Broaddus
Utility of MLH1 methylation analysis in the clinical evaluation of lynch syndrome in women with endometrial cancer
Yesid Alvarado; Hagop M. Kantarjian; Rajyalakshmi Luthra; Farhad Ravandi; Gautam Borthakur; Guillermo Garcia-Manero; Marina Konopleva; Zeev Estrov; Michael Andreeff; Jorge E. Cortes
Treatment with FLT3 inhibitor in patients with FLT3-mutated acute myeloid leukemia is associated with development of secondary FLT3-tyrosine kinase domain mutations
Alexandar Tzankov; Zijun Y. Xu-Monette; Marc Gerhard; Carlo Visco; Stephan Dirnhofer; Nora Gisin; Karen Dybkaer; Attilio Orazi; Govind Bhagat; Kristy L. Richards; et al.
Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP
F. Ravandi; C. Arana Yi; J.E. Cortes; M. Levis; S. Faderl; G. Garcia-Manero; E. Jabbour; M. Konopleva; S. O'Brien; Z. Estrov; et al.
Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia
Shi Wang; L. Jeffrey Medeiros; Zijun Y. Xu-Monette; Shanxiang Zhang; Dennis P. O'Malley; Attilio Orazi; Zhuang Zuo; Carlos E. Bueso-Ramos; Cameron C. Yin; Zhiyu Liu; et al.
Epstein-Barr virus-positive nodular lymphocyte predominant Hodgkin lymphoma
Amanda S. Bruegl; Bojana Djordjevic; Brittany Batte; Molly Daniels; Bryan Fellman; Diana Urbauer; Rajyalakshmi Luthra; Charlotte Sun; Karen H. Lu; Russell R. Broaddus
Evaluation of clinical criteria for the identification of Lynch syndrome among unselected patients with endometrial cancer
Martha Rodriguez Sandoval; Kumudha Balakrishnan; Rajyalakshmi Luthra; Michael Keating; Varsha Gandhi
DNA repair initiation induces expression of ribonucleotide reductase in human chronic lymphocytic leukemia cells
Galactoxyloglucan-modified nanocarriers of doxorubicin for improved tumor-targeted drug delivery with minimal toxicity
Brittany A.L. Batte; Amanda S. Bruegl; Molly S. Daniels; Kari L. Ring; Katherine M. Dempsey; Bojana Djordjevic; Rajyalakshmi Luthra; Bryan M. Fellman; Karen H. Lu; Russell R. Broaddus
Consequences of universal MSI/IHC in screening ENDOMETRIAL cancer patients for lynch syndrome
Rajesh Radhakrishnan; Suraj K. George; Sunil Kumar; Prabha Balaram
Maintenance of immunological homeostasis by Indukantha Ghritha in patients with recurrent upper respiratory tract infections - A pilot study
Suraj Konnath George; Deeksha Vishwamitra; Roxsan Manshouri; Ping Shi; Hesham M. Amin
The ALK inhibitor ASP3026 eradicates NPM-ALK+ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model
Tamer M. Fouad; Takahiro Kogawa; James M. Reuben; Naoto T. Ueno
The role of inflammation in inflammatory breast cancer
Alberto Paniz-Mondolfi; Rajesh Singh; George Jour; Mandana Mahmoodi; A Hafeez Diwan; Bedia A Barkoh; Ronald Cason; Yve Huttenbach; Gustavo Benaim; John Galbincea; et al.
Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing.
Alberto E. Paniz Mondolfi; George Jour; Matthew Johnson; Jason Reidy; Ronald C. Cason; Bedia A. Barkoh; Gustavo Benaim; Rajesh Singh; Rajyalakshmi Luthra
Primary cutaneous carcinosarcoma: Insights into its clonal origin and mutational pattern expression analysis through next-generation sequencing
Shi Wang; Alexander Tzankov; Zijun Y. Xu-Monette; Sylvia Hoeller; Sa A. Wang; Kristy L. Richards; Shanxiang Zhang; Jonathan W. Said; L. Jeffrey Medeiros; Ken H. Young
Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications
Khaled Alayed; Keyur P. Patel; Sergej Konoplev; Rajesh R. Singh; Mark J. Routbort; Neelima Reddy; Naveen Pemmaraju; Liping Zhang; Abdulaziz Al Shaikh; Tariq N. Aladily; et al.
TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow
Lorenzo Falchi; Hagop M. Kantarjian; Xuemei Wang; Dushyant Verma; Alfonso Quintás-Cardama; Susan O'Brien; Elias J. Jabbour; Farhad Ravandi-Kashani; Gautam Borthakur; Guillermo Garcia-Manero; et al.
Significance of deeper molecular responses in patients with chronic myeloid leukemia in early chronic phase treated with tyrosine kinase inhibitors
Prasanth Ganesan; Filip Janku; Aung Naing; David S. Hong; Apostolia M. Tsimberidou; Gerald S. Falchook; Jennifer J. Wheler; Sarina A. Piha-Paul; Siqing Fu; Vanda M. Stepanek; et al.
Target-Based therapeutic matching in early-Phase clinical trials in patients with advanced colorectal cancer and pik3ca mutations
Koichi Takahashi; Keyur P. Patel; Hagop Kantarjian; Rajyalakshmi Luthra; Sherry Pierce; Jorge Cortes; Srdan Verstovsek
JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms
Hiroko Masuda; Keith A. Baggerly; Ying Wang; Takayuki Iwamoto; Takae Brewer; Lajos Pusztai; Kazuharu Kai; Takahiro Kogawa; Pascal Finetti; Daniel Birnbaum; et al.
Comparison of molecular subtype distribution in triple-negative inflammatory and non-inflammatory breast cancers
Aziz Nazha; Hagop Kantarjian; Preetesh Jain; Carlos Romo; Elias Jabbour; Alfonso Quintas-Cardama; Raja Luthra; Lynne Abruzzo; Gautam Borthakur; Farhad Ravandi; et al.
Assessment at 6 months may be warranted for patients with chronic myeloid leukemia with no major cytogenetic response at 3 months
Xiaoping Wang; Hitomi Saso; Takayuki Iwamoto; Weiya Xia; Yun Gong; Lajos Pusztai; Wendy A. Woodward; James M. Reuben; Steven L. Warner; David J. Bearss; et al.
TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase
Liang Zhang; Lan V. Pham; Kate J. Newberry; Zhishuo Ou; Rong Liang; Jianfei Qian; Luhong Sun; Marzenna Blonska; Yun You; Jing Yang; et al.
In vitro and in vivo therapeutic efficacy of carfilzomib in mantle cell lymphoma: Targeting the immunoproteasome
E. Frei; C. Visco; Z.Y. Xu-Monette; S. Dirnhofer; K. Dybkræ; A. Orazi; G. Bhagat; E.D. Hsi; J.H. Van Krieken; M. Ponzoni; et al.
Addition of rituximab to chemotherapy overcomes the negative prognostic impact of cyclin E expression in diffuse large B-cell lymphoma
Yong Bao; ShiLiang Liu; QiChao Zhou; PeiQiang Cai; Simone Anfossi; QiaoQiao Li; YongHong Hu; MengZhong Liu; JianHua Fu; TieHua Rong; et al.
Three-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: Clinical efficacy and failure pattern
Koichi Takahashi; Naveen Pemmaraju; Paolo Strati; Graciela Nogueras-Gonzalez; Jing Ning; Carlos Bueso-Ramos; Rajyalakshmi Luthra; Sherry Pierce; Jorge Cortes; Hagop Kantarjian; et al.
Clinical characteristics and outcomes of therapy-related chronic myelomonocytic leukemia
Zijun Y Xu-Monette; Michael B Møller; Alexander Tzankov; Santiago Montes-Moreno; Wenwei Hu; Ganiraju C Manyam; Louise Kristensen; Lei Fan; Carlo Visco; Karen Dybkaer; et al.
MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program.
Feng-Pai Chou; Ya-Wen Chen; Xianfeng F. Zhao; Zijun Y. Xu-Monette; Ken H. Young; Ronald B. Gartenhaus; Jehng-Kang Wang; Hiroaki Kataoka; Annie H. Zuo; Robert J. Barndt; et al.
Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-Cell lymphomas
A. Giordano; H. Gao; E.N. Cohen; S. Anfossi; J. Khoury; K. Hess; S. Krishnamurthy; S. Tin; M. Cristofanilli; G.N. Hortobagyi; et al.
Clinical relevance of cancer stem cells in bone marrow of early breast cancer patients
Yi Zhou; Xiangshan Fan; Mark Routbort; C. Cameron Yin; Rajesh Singh; Carlos Bueso-Ramos; Deborah A Thomas; Denái R Milton; L Jeffrey Medeiros; Pei Lin
Absence of terminal deoxynucleotidyl transferase expression identifies a subset of high-risk adult T-lymphoblastic leukemia/lymphoma
Bojana Djordjevic; Bedia A Barkoh; Rajyalakshmi Luthra; Russell R Broaddus
Relationship between PTEN, DNA mismatch repair, and tumor histotype in endometrial carcinoma: Retained positive expression of PTEN preferentially identifies sporadic non-endometrioid carcinomas
K. Takahashi; E. Jabbour; X. Wang; R. Luthra; C. Bueso-Ramos; K. Patel; S. Pierce; H. Yang; Y. Wei; N. Daver; et al.
Dynamic acquisition of FLT3 or RAS alterations drive a subset of patients with lower risk MDS to secondary AML
Rajesh R. Singh; Kumaralal Kaluarachchi; Mingzhi Chen; Suresh K. Rayala; Seetharaman Balasenthil; Jianpeng Ma; Rakesh Kumar
Erratum: Solution structure and antiestrogenic activity of the unique C-terminal, NR-box motif-containing region of MTA1s (The Journal of Biological Chemistry (2013) 288 (27518))
Alessandra Ferrajoli; Tait D. Shanafelt; Cristina Ivan; Masayoshi Shimizu; Kari G. Rabe; Nazila Nouraee; Mariko Ikuo; Asish K. Ghosh; Susan Lerner; Laura Z. Rassenti; et al.
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia
Meenakshi Mehrotra; Indraneel Sanyal; D.V. Amla
Erratum to Retraction Note: High-efficiency Agrobacterium-mediated transformation of chickpea (Cicer arietinum L.) and regeneration of insect-resistant transgenic plants (Retraction to: Plant Cell Rep, (2011) 30, (1603-1616), 10.1007/s00299-011-1071-5)
Rajesh R. Singh; Keyur P. Patel; Mark J. Routbort; Neelima G. Reddy; Bedia A. Barkoh; Brian Handal; Rashmi Kanagal-Shamanna; Wesley O. Greaves; L. Jeffrey Medeiros; Kenneth D. Aldape; et al.
Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes
Steven J. Van Laere; Naoto T. Ueno; Pascal Finetti; Peter Vermeulen; Anthony Lucci; Fredika M. Robertson; Melike Marsan; Takayuki Iwamoto; Savitri Krishnamurthy; Hiroko Masuda; et al.
Uncovering the molecular secrets of inflammatory breast cancer biology: An integrated analysis of three distinct affymetrix gene expression datasets
Wei Xu; Lara Lacerda; Bisrat G. Debeb; Rachel L. Atkinson; Travis N. Solley; Li Li; Darren Orton; John S. McMurray; Brian I. Hang; Ethan Lee; et al.
The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer
Farhad Ravandi; Jeffrey L. Jorgensen; Deborah A. Thomas; Susan O'Brien; Rebecca Garris; Stefan Faderl; Xuelin Huang; Sijin Wen; Jan A. Burger; Alessandra Ferrajoli; et al.
Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy
Nathan Lee; Rajyalakshmi Luthra; Dolores Lopez-Terrada; Wei-Lien Wang; Alexander J. Lazar
Retroperitoneal undifferentiated pleomorphic sarcoma having microsatellite instability associated with Muir-Torre syndrome: Case report and review of literature
Paolo Strati; Michael J. Keating; William G. Wierda; Xavier C. Badoux; Steliana Calin; James M. Reuben; Susan O'Brien; Steven M. Kornblau; Hagop M. Kantarjian; Hui Gao; et al.
Lenalidomide induces long-lasting responses in elderly patients with chronic lymphocytic leukemia
T.M. Brewer; H. Masuda; D.D. Liu; Y. Shen; P. Liu; T. Iwamoto; K. Kai; C.M. Barnett; W.A. Woodward; J.M. Reuben; et al.
Statin use in primary inflammatory breast cancer: A cohort study
Wesley O. Greaves; Shalini Verma; Tigist Bisrat; Paolo Strati; Hamed Rahimi; Abhaya V. Paladugu; Rajyalakshmi Luthra; Keyur P. Patel; L. Jeffrey Medeiros; Hui Yao; et al.
TP53 mutation is rare in primary myelofibrosis
Changju Qu; Yadong Liu; Kranthi Kunkalla; Rajesh R Singh; Marzenna Blonska; Xin Lin; Nitin Kumar Agarwal; Francisco Vega
Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma.
Kranthi Kunkalla; Yadong Liu; Changju Qu; Vasiliki Leventaki; Nitin K. Agarwal; Rajesh R. Singh; Francisco Vega
Functional inhibition of BCL2 is needed to increase the susceptibility to apoptosis to SMO inhibitors in diffuse large B-cell lymphoma of germinal center subtype
Koichi Takahashi; Hagop Kantarjian; Naveen Pemmaraju; Michael Andreeff; Gautam Borthakur; Stefan Faderl; Guillermo Garcia-Manero; Sherry Pierce; Rajyalakshmi Luthra; Marylou Cardenas-Turanzas; et al.
Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD
Yong Li; Michael W Gordon; Zijun Y Xu-Monette; Carlo Visco; Alexander Tzankov; Dehui Zou; Lugui Qiu; Santiago Montes-Moreno; Karen Dybkaer; Attilio Orazi; et al.
Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program.
Shimin Hu; Zijun Y Xu-Monette; Alexander Tzankov; Tina Green; Lin Wu; Aarthi Balasubramanyam; Wei-min Liu; Carlo Visco; Yong Li; Roberto N Miranda; et al.
MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program.
Aref Al-Kali; Alfonso Quintás-Cardama; Raja Luthra; Carlos Bueso-Ramos; Sherry Pierce; Tapan Kadia; Gautam Borthakur; Zeev Estrov; Elias Jabbour; Stefan Faderl; et al.
Prognostic impact of RAS mutations in patients with myelodysplastic syndrome
Paul Collier; Keyur Patel; Paul Waeltz; Mark Rupar; Rajyalakshmi Luthra; Phillip C.C. Liu; Gregory Hollis; Reid Huber; Srdan Verstovsek; Timothy C. Burn
Validation of standards for quantitative assessment of JAK2 c.1849G>T (p.V617F) allele burden analysis in clinical samples
J.P. Cata; H. Wang; V. Gottumukkala; J. Reuben; D.I. Sessler
Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions
Shimin Hu; Zijun Y Xu-Monette; Aarthi Balasubramanyam; Ganiraju C Manyam; Carlo Visco; Alexander Tzankov; Wei-min Liu; Roberto N Miranda; L. Zhang; Santiago Montes-Moreno; et al.
CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study.
Wendy A. Woodward; Savitri Krishnamurthy; Hideko Yamauchi; Randa El-Zein; Dai Ogura; Eri Kitadai; Shin-Ichiro Niwa; Massimo Cristofanilli; Peter Vermeulen; Luc Dirix; et al.
Genomic and expression analysis of microdissected inflammatory breast cancer
Antonio Giordano; Brian L. Egleston; David Hajage; Joseph Bland; Gabriel N. Hortobagyi; James M. Reuben; Jean-Yves Pierga; Massimo Cristofanilli; Francois-Clement Bidard
Establishment and validation of circulating tumor cell-based prognostic nomograms in first-line metastatic breast cancer patients
Anupama E. Gururaj; Rajesh R. Singh; Suresh K. Rayala; Caroline Holm; Petra Den Hollander; Hao Zhang; Seetharaman Balasenthil; Amjad H. Talukder; Goran Landberg; Rakesh Kumar
Erratum: MTA1, a transcriptional activator of breast cancer amplified sequence 3 (Proceedings of the National Academy of Sciences of the United States of America (2006) 103 (6670-6675) DOI: 10.1073/pnas.0601989103)
Wesley O. Greaves; Shalini Verma; Keyur P. Patel; Michael A. Davies; Bedia A. Barkoh; John M. Galbincea; Hui Yao; Alexander J. Lazar; Kenneth D. Aldape; L. Jeffrey Medeiros; et al.
Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma
Carlo Visco; Alexander Tzankov; Zijun Y. Xu-Monette; Roberto N. Miranda; Yu Chuan Tai; Yan Li; Wei-Min Liu; Emanuele S.G. d'Amore; Yong Li; Santiago Montes-Moreno; et al.
Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: A report from an international DLBCL rituximab-CHOP consortium program study
Sylvia Hoeller; Yi Zhou; Rashmi Kanagal-Shamanna; Zijun Y. Xu-Monette; Daniela Hoehn; Michel Bihl; Steven H. Swerdlow; Andreas Rosenwald; German Ott; Jonathan Said; et al.
Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: A clinicopathologic and molecular study
Kejie Zhang; Michael Wang; Archito T. Tamayo; Sharon Shacham; Michael Kauffman; John Lee; Liang Zhang; Zhishuo Ou; Changping Li; Luhong Sun; et al.
Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma
Sergej Konoplev; C. Cameron Yin; Steven M. Kornblau; Hagop M. Kantarjian; Marina Konopleva; Michael Andreeff; Gary Lu; Zhuang Zuo; Rajyalakshmi Luthra; L. Jeffrey Medeiros; et al.
Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia
Naval Daver; Paolo Strati; Elias Jabbour; Tapan Kadia; Raja Luthra; Sa Wang; Keyur Patel; Farhad Ravandi; Jorge Cortes; Xiao Qin Dong; et al.
FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia
Manu M. Joseph; S.R. Aravind; Suraj K. George; Sheeja Varghese; T.T. Sreelekha
A galactomannan polysaccharide from Punica granatum imparts in vitro and in vivo anticancer activity
Filip Janku; Jennifer J. Wheler; Aung Naing; Gerald S. Falchook; David S. Hong; Vanda M. Stepanek; Siqing Fu; Sarina A. Piha-Paul; J. Jack Lee; Rajyalakshmi Luthra; et al.
PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials
Suraj Konnath George; Veronica Tovar-Sepulveda; Steven S. Shen; Weiguo Jian; Yiqun Zhang; Susan G. Hilsenbeck; Seth P. Lerner; Carolyn L. Smith
Chemoprevention of BBN-induced bladder carcinogenesis by the selective Estrogen receptor modulator tamoxifen
Emma Yue Zhang; Massimo Cristofanilli; Fredika Robertson; James M. Reuben; Zhaomei Mu; Ronald C. Beavis; Hogune Im; Michael Snyder; Matan Hofree; Trey Ideker; et al.
Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer
C. Cameron Yin; Rajyalakshmi Luthra
Molecular detection of t(11;14)(q13;q32) in mantle cell lymphoma
Molecular detection of t(14;18)(q32;q21) in follicular lymphoma
Detection of t(2;5)(p23;q35) in anaplastic large-cell lymphoma by long-range nested polymerase chain reaction assay
Savitri Krishnamurthy; Wendy Woodward; Wei Yang; James M. Reuben; James Tepperberg; Dai Ogura; Shin-Ichiro Niwa; Lei Huo; Yun Gong; Randa El-Zein; et al.
Status of the anaplastic lymphoma kinase (ALK) gene in inflammatory breast carcinoma
Gautam Borthakur; Hagop Kantarjian; Keyur P. Patel; Farhad Ravandi; Wei Qiao; Stefan Faderl; Tapan Kadia; Raja Luthra; Sherry Pierce; Jorge E. Cortes
Impact of numerical variation in FMS-like tyrosine kinase receptor 3 internal tandem duplications on clinical outcome in normal karyotype acute myelogenous leukemia
Filip Janku; Jennifer J. Wheler; Aung Naing; Vanda M. Stepanek; Gerald S. Falchook; Siqing Fu; Ignacio Garrido-Laguna; Apostolia M. Tsimberidou; Sarina A. Piha-Paul; Stacy L. Moulder; et al.
PIK3CA mutations in advanced cancers: Characteristics and outcomes
Tapan M. Kadia; Hagop Kantarjian; Steven Kornblau; Gautam Borthakur; Stefan Faderl; Emil J. Freireich; Raja Luthra; Guillermo Garcia-Manero; Sherry Pierce; Jorge Cortes; et al.
Clinical and proteomic characterization of acute myeloid leukemia with mutated RAS
Apostolia-Maria Tsimberidou; Nancy G. Iskander; David S. Hong; Jennifer J. Wheler; Gerald S. Falchook; Siqing Fu; Sarina Piha-Paul; Aung Naing; Filip Janku; Rajyalakshmi Luthra; et al.
Personalized medicine in a phase I clinical trials program: The MD Anderson Cancer Center Initiative
Zijun Y. Xu-Monette; Lin Wu; Carlo Visco; Yu Chuan Tai; Alexander Tzankov; Wei-Min Liu; Santiago Montes-Moreno; Karen Dybkær; April Chiu; Attilio Orazi; et al.
Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: Report from an International DLBCL Rituximab-CHOP Consortium Program Study
Roxana S. Redis; Steliana Calin; Yaling Yang; M. James You; George A. Calin
Cell-to-cell miRNA transfer: From body homeostasis to therapy
Bisrat G. Debeb; Lara Lacerda; Wei Xu; Richard Larson; Travis Solley; Rachel Atkinson; Erik P. Sulman; Naoto T. Ueno; Savitri Krishnamurthy; James M. Reuben; et al.
Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/β-catenin signaling
Antonio Giordano; Hui Gao; Simone Anfossi; Evan Cohen; Michal Mego; Bang-Ning Lee; Sanda Tin; Michele De Laurentiis; Charla A. Parker; Ricardo H. Alvarez; et al.
Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer
Sriram Yennurajalingam; Jie S. Willey; J. Lynn Palmer; Julio Allo; Egidio Del Fabbro; Evan N. Cohen; Sanda Tin; James M. Reuben; Eduardo Bruera
The role of thalidomide and placebo for the treatment of cancer-related anorexia-cachexia symptoms: Results of a double-blind placebo-controlled randomized study
Mikako Warren; Rajyalakshmi Luthra; C Cameron Yin; Farhad Ravandi; Jorge E. Cortes; Hagop M. Kantarjian; L Jeffrey Medeiros; Zhuang Zuo
Clinical impact of change of FLT3 mutation status in acute myeloid leukemia patients
Tina Marie Green; Ken H. Young; Carlo Visco; Zijun Y. Xu-Monette; Attilio Orazi; Ronald S. Go; Ole Nielsen; Ole V. Gadeberg; Torben Mourits-Andersen; Mikael Frederiksen; et al.
Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone
Elisa Ramirez; Rajesh R. Singh; Kranthi Kunkalla; Yadong Liu; Changju Qu; Christine Cain; Asha S. Multani; Patrick A. Lennon; Jared Jackacky; Michael Ho; et al.
Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma
Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: A report from the International DLBCL Rituximab-CHOP Consortium Program Study
Mi-Ae Lyu; Lan V. Pham; Bokyung Sung; Archito T. Tamayo; Kwang Seok Ahn; Walter N. Hittelman; Lawrence H. Cheung; John W. Marks; Min-Jeong Cho; Richard J. Ford; et al.
The therapeutic effects of rGel/BLyS fusion toxin in in vitro and in vivo models of mantle cell lymphoma
Kjersti Tjensvoll; Kine N. Svendsen; James M. Reuben; Satu Oltedal; Bjornar Gilje; Rune Smaaland; Oddmund Nordgård
MiRNA expression profiling for identification of potential breast cancer biomarkers
Aziz Nazha; Jorge Cortes; Stefan Faderl; Sherry Pierce; Naval Daver; Tapan Kadia; Gautam Borthakur; Raja Luthra; Hagop Kantarjian; Farhad Ravandi
Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia
Ugo De Giorgi; Michal Mego; Emanuela Scarpi; Mario Giuliano; Antonio Giordano; James M. Reuben; Vicente Valero; Naoto T. Ueno; Gabriel N. Hortobagyi; Massimo Cristofanilli
Relationship between lymphocytopenia and circulating tumor cells as prognostic factors for overall survival in metastatic breast cancer
Zhuang Zuo; L. Jeffrey Medeiros; Zhao Chen; Dingsheng Liu; Carlos E. Bueso-Ramos; Rajyalakshmi Luthra; Sa A. Wang
Acute myeloid leukemia (AML) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of AML
Samuel B. Foster; Ming Lu; Daniel G. Glaze; James M. Reuben; Lynnette L. Harris; Evan N. Cohen; Bang-Ning Lee; Enxu Zhao; Mary E. Paul; Heidi Schwarzwald; et al.
Associations of cytokines, sleep patterns, and neurocognitive function in youth with HIV infection
Rajesh R. Singh; Ashish Bains; Keyur P. Patel; Hamed Rahimi; Bedia A. Barkoh; Abhaya Paladugu; Tigist Bisrat; Farhad Ravandi-Kashani; Jorge E. Cortes; Hagop M. Kantarjian; et al.
Detection of high-frequency and novel DNMT3A mutations in acute myeloid leukemia by high-resolution melting curve analysis
Hideko Yamauchi; Wendy A. Woodward; Vicente Valero; Ricardo H. Alvarez; Anthony Lucci; Thomas A. Buchholz; Takayuki Iwamoto; Savitri Krishnamurthy; Wei Yang; James M. Reuben; et al.
Inflammatory breast cancer: What we know and what we need to learn
Shalini Verma; Wesley O. Greaves; Farhad Ravandi; Neelima Reddy; Carlos E. Bueso-Ramos; Susan O'Brien; Deborah A. Thomas; Hagop Kantarjian; L. Jeffrey Medeiros; Rajyalakshmi Luthra; et al.
Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay
Bisrat G. Debeb; Evan N. Cohen; Kimberly Boley; Erik M. Freiter; Li Li; Fredika M. Robertson; James M. Reuben; Massimo Cristofanilli; Thomas A. Buchholz; Wendy A. Woodward
Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells
Ignacio Garrido-Laguna; David S. Hong; Filip Janku; Ly M. Nguyen; Gerald S. Falchook; Siqing Fu; Jenifer J. Wheler; Rajyalakshmi Luthra; Aung Naing; Xuemei Wang; et al.
KRASness and PIK3CAness in patients with advanced colorectal cancer: Outcome after treatment with early-phase trials with targeted pathway inhibitors
Kjersti Tjensvoll; Satu Oltedal; Reino Heikkilä; Jan T. Kvaloy; Bjørnarørnar Gilje; James M. Reuben; Rune Smaaland; Oddmund Nordgard
Persistent tumor cells in bone marrow of non-metastatic breast cancer patients after primary surgery are associated with inferior outcome
Farhad Ravandi; Keyur Patel; Rajyalakshmi Luthra; Stefan Faderl; Marina Konopleva; Tapan Kadia; Mark Brandt; Sherry Pierce; Steven Kornblau; Michael Andreeff; et al.
Prognostic significance of alterations in IDH enzyme isoforms in patients with AML treated with high-dose cytarabine and idarubicin
Tariq Al-Zaid; Jeremy S. Ditelberg; Victor G. Prieto; Dina Lev; Raja Luthra; Michael A. Davies; A. Hafeez Diwan; Wei-Lien Wang; Alexander J. Lazar
Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors
A. Giordano; M. Giuliano; M. De laurentiis; G. Arpino; S. Jackson; B.C. Handy; N.T. Ueno; E. Andreopoulou; R.H. Alvarez; V. Valero; et al.
Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: Lack of prediction in HER2-positive disease treated with targeted therapy
Deqin Ma; Zhao Chen; Christopher Nero; Keyur P. Patel; Emad M. Daoud; Hanyin Cheng; Bojana Djordjevic; Russell R. Broaddus; L. Jeffrey Medeiros; Asif Rashid; et al.
Somatic deletions of the PolyA Tract in the 39 untranslated region of epidermal growth factor receptor are common in microsatellite instability-high endometrial and colorectal carcinomas
Zijun Y. Xu-Monette; Ken H. Young
The TP53 tumor suppressor and autophagy in malignant lymphoma
Bojana Djordjevic; Bryan T. Hennessy; Jie Li; Bedia A. Barkoh; Rajyalakshmi Luthra; Gordon B. Mills; Russell R. Broaddus
Clinical assessment of PTEN loss in endometrial carcinoma: Immunohistochemistry outperforms gene sequencing
Zijun Y. Xu-Monette; L. Jeffrey Medeiros; Yong Li; Robert Z. Orlowski; Michael Andreeff; Carlos E. Bueso-Ramos; Timothy C. Greiner; Timothy J. McDonnell; Ken H. Young
Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies
E. Andreopoulou; L.-Y. Yang; K.M. Rangel; J.M. Reuben; L. Hsu; S. Krishnamurthy; V. Valero; H.A. Fritsche; M. Cristofanilli
Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect™ versus Veridex CellSearch™ system
Partow Kebriaei; Rima Saliba; Gabriela Rondon; Alexandre Chiattone; Rajyalakshmi Luthra; Paolo Anderlini; Borje Andersson; Elizabeth Shpall; Uday Popat; Roy Jones; et al.
Long-term follow-up of allogeneic hematopoietic stem cell transplantation for patients with philadelphia chromosome-positive acute lymphoblastic leukemia: Impact of tyrosine kinase inhibitors on treatment outcomes
Tina Marie Green; Ole Nielsen; Karin De Stricker; Zijun Y. Xu-Monette; Ken H. Young; Michael Boe Møller
High levels of nuclear MYC protein predict the presence of myc rearrangement in diffuse large B-cell lymphoma
Filip Janku; Jennifer J. Wheler; Shannon N. Westin; Stacy L. Moulder; Aung Naing; Apostolia M. Tsimberidou; Siqing Fu; Gerald S. Falchook; David S. Hong; Ignacio Garrido-Laguna; et al.
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
Ashish Bains; Gary Lu; Hui Yao; Rajalakshmi Luthra; L. Jeffrey Medeiros; Rachel L. Sargent
Molecular and clinicopathologic characterization of AML with isolated trisomy 4
Changping Li; Michael A. Thompson; Archito T. Tamayo; Zhuang Zuo; John Lee; Francisco Vega; Richard J. Ford; Lan V. Pham
Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma
Michal Mego; Sendurai A. Mani; Bang-Ning Lee; Changping Li; Kurt W. Evans; Evan N. Cohen; Hui Gao; Summer A. Jackson; Antonio Giordano; Gabriel N. Hortobagyi; et al.
Expression of epithelial-mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapy
Lucas Moretti; L Jeffrey Medeiros; Kranthi Kunkalla; Michelle D. Williams; Rajesh R. Singh; Francisco Vega
N-terminal PAX8 polyclonal antibody shows cross-reactivity with N-terminal region of PAX5 and is responsible for reports of PAX8 positivity in malignant lymphomas
Benjamin Ellezam; Brett J. Theeler; Rajyalakshmi Luthra; Adekunle M. Adesina; Kenneth D. Aldape; Mark R. Gilbert
Recurrent PIK3CA mutations in rosette-forming glioneuronal tumor
Angela N. Bartley; Rajyalakshmi Luthra; Devki S. Saraiya; Diana L. Urbauer; Russell R. Broaddus
Identification of cancer patients with lynch syndrome: Clinically significant discordances and problems in tissue-based mismatch repair testing
M. Mego; J.M. Reuben
Circulating tumour cells in the central and the peripheral venous compartment in patients with metastatic breast cancer
Chi Young Ok; Rajesh Ramachandra Singh; Francisco Vega
Aberrant activation of the hedgehog signaling pathway in malignant hematological neoplasms
Charles Lu; David J Stewart; J Jack Lee; Lin Ji; Rajagopal Ramesh; Gitanjali Jayachandran; Maria I Nunez; Ignacio I Wistuba; Jeremy J Erasmus; Marshall E Hicks; et al.
Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
Yujun Song; Yuanqing Zhang; Paul E. Bernard; James M. Reuben; Naoto T. Ueno; Ralph B. Arlinghaus; Youli Zu; Lidong Qin
Multiplexed volumetric bar-chart chip for point-of-care diagnostics
Michal Mego; Hui Gao; Bang-Ning Lee; Evan N. Cohen; Sanda Tin; Antonio Giordano; Qiong Wu; Ping Liu; Yago Nieto; Richard E. Champlin; et al.
Prognostic value of EMT-circulating tumor cells in metastatic breast can-cer patients undergoing high-dose chemotherapy with autologous hematopoietic stem cell transplantation
Wesley Greaves; Lianchun Xiao; Beatriz Sanchez-Espiridion; Kranthi Kunkalla; Kunal S. Dave; Cynthia S. Liang; Rajesh R. Singh; Anas Younes; L Jeffrey Medeiros; Francisco Vega
Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols
Carmen D. Schweighofer; Kevin R. Coombes; Lynn L. Barron; Lixia Diao; Rachel J. Newman; Alessandra Ferrajoli; Susan O'Brien; William G. Wierda; Rajyalakshmi Luthra; L. Jeffrey Medeiros; et al.
A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia
R.R. Singh; K. Kunkalla; C. Qu; E. Schlette; S.S. Neelapu; F. Samaniego; F. Vega
ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
Angela N. Bartley; Hui Yao; Bedia A. Barkoh; Cristina Ivan; Bal M. Mishra; Asif Rashid; George A. Calin; Rajyalakshmi Luthra; Stanley R. Hamilton
Complex patterns of altered microRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer
Keyur P. Patel; Bedia A. Barkoh; Zhao Chen; Deqin Ma; Neelima Reddy; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Diagnostic testing for IDH1 and IDH2 variants in acute myeloid leukemia: An algorithmic approach using high-resolution melting curve analysis
Wesley O. Greaves; Ji Eun Kim; Rajesh R. Singh; Elias Drakos; Kranthi Kunkalla; Beatriz Sánchez-Espiridión; Juan F. Garcia; L. Jeffrey Medeiros; Francisco Vega
Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
Meenakshi Mehrotra; Aditya K. Singh; Indraneel Sanyal; Illimar Altosaar; D.V. Amla
Pyramiding of modified cry1Ab and cry1Ac genes of Bacillus thuringiensis in transgenic chickpea (Cicer arietinum L.) for improved resistance to pod borer insect Helicoverpa armigera
Farhad Ravandi; Susan O'Brien; Jeffrey Jorgensen; Sherry Pierce; Stefan Faderl; Alessandra Ferrajoli; Charles Koller; Pramoda Challagundla; Sergernne York; Mark Brandt; et al.
Phase 2 study of cladribine followed by rituximab in patients with hairy cell leukemia
Xavier C. Badoux; Michael J. Keating; Sijin Wen; Bang-Ning Lee; Mariela Sivina; James Reuben; William G. Wierda; Susan M. O'Brien; Stefan Faderl; Steven M. Kornblau; et al.
Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia
Antonio Giordano; Mario Giuliano; Michelino De Laurentiis; Antonio Eleuteri; Francesco Iorio; Roberto Tagliaferri; Gabriel N. Hortobagyi; Lajos Pusztai; Sabino De Placido; Kenneth Hess; et al.
Artificial neural network analysis of circulating tumor cells in metastatic breast cancer patients
High-efficiency Agrobacterium-mediated transformation of chickpea (Cicer arietinum L.) and regeneration of insect-resistant transgenic plants
Bang-Ning Lee; Hui Gao; Evan N. Cohen; Xavier Badoux; William G. Wierda; Zeev Estrov; Stefan H. Faderl; Michael J. Keating; Alessandra Ferrajoli; James M. Reuben
Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia
Fareed H. Barakat; Rajyalakshmi Luthra; C. Cameron Yin; Bedia A. Barkoh; Seema Hai; Waqar Jamil; Yaminiben I. Bhakta; Su Chen; L. Jeffrey Medeiros; Zhuang Zuo
Detection of nucleophosmin 1 mutations by quantitative real-time polymerase chain reaction versus capillary electrophoresis: A comparative study
Santiago Montes-Moreno; Nerea Martinez; Beatriz Sanchez-Espiridión; Ramon Díaz Uriarte; Maria Elena Rodriguez; Anabel Saez; Carlos Montalbán; Gonzalo Gomez; David G. Pisano; Juan Fernando García; et al.
MiRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy
Michal Mego; Ugo De Giorgi; Shahenaah Dawood; Xuemei Wang; Vicente Valero; Eleni Andreopoulou; Beverly Handy; Naoto T. Ueno; James M. Reuben; Massimo Cristofanilli
Characterization of metastatic breast cancer patients with nondetectable circulating tumor cells
James M. Reuben; Bang-Ning Lee; Hui Gao; Evan N. Cohen; Michel Mego; Antonio Giordano; Xuemei Wang; Ashutosh Lodhi; Savitri Krishnamurthy; Gabriel N. Hortobagyi; et al.
Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44 +CD24 lo cancer stem cell phenotype
Mario Giuliano; Antonio Giordano; Summer Jackson; Kenneth R. Hess; Ugo De Giorgi; Michal Mego; Beverly C. Handy; Naoto T. Ueno; Ricardo H. Alvarez; Michelino De Laurentiis; et al.
Circulating tumor cells as prognostic and predictive markers in metastatic breast cancer patients receiving first-line systemic treatment
Carmen D. Schweighofer; Yang O. Huh; Rajyalakshmi Luthra; Rachel L. Sargent; Rhett P. Ketterling; Ryan A. Knudson; Lynn L. Barron; L. Jeffrey Medeiros; Michael J. Keating; Lynne V. Abruzzo
The B cell antigen receptor in atypical chronic lymphocytic leukemia with t(14;19)(q32;q13) demonstrates remarkable stereotypy
Deqin Ma; Chen Zhao; Keyur P. Patel; Bal M. Mishra; Yao Hui; Lynne V. Abruzzo; L. Jeffrey Medeiros; William Wierda; Michael Keating; Rachel Sargent; et al.
Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic leukemia
Yang O. Huh; Carmen D. Schweighofer; Rhett P. Ketterling; Ryan A. Knudson; Francisco Vega; Ji E. Kim; Rajyalakshmi Luthra; Michael J. Keating; L. Jeffrey Medeiros; Lynne V. Abruzzo
Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features
Ugo De Giorgi; Evan N. Cohen; Hui Gao; Michal Mego; Bang-Ning Lee; Ashutosh Lodhi; Massimo Cristofanilli; Anthony Lucci; James M. Reuben
Mesenchymal stem cells expressing GD2 and CD271 correlate with breast cancer-initiating cells in bone marrow
E. Drakos; R.R. Singh; G.Z. Rassidakis; E. Schlette; J. Li; F.X. Claret; R.J. Ford Jr.; F. Vega; L.J. Medeiros
Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21)
Davide Rossi; Valeria Spina; Clara Deambrogi; Silvia Rasi; Luca Laurenti; Kostas Stamatopoulos; Luca Arcaini; Marco Lucioni; Gabrielle B. Rocque; Zijun Y. Xu-Monette; et al.
The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
Inga Gurevich; Raja Luthra; Sergej N. Konoplev; C. Cameron Yin; L. Jeffrey Medeiros; Pei Lin
Refractory anemia with ring sideroblasts associated with marked thrombocytosis: A mixed group exhibiting a spectrum of morphologic findings
Filip Janku; Apostolia M. Tsimberidou; Ignacio Garrido-Laguna; Xuemei Wang; Rajyalakshmi Luthra; David S. Hong; Aung Naing; Gerald S. Falchook; John W. Moroney; Sarina A. Piha-Paul; et al.
PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors
Carlo Visco; Sylvia Hoeller; Jeffrey T. Malik; Zijun Y. Xu-Monette; Michele L. Wiggins; Jessica Liu; Warren G. Sanger; Zhongfeng Liu; Julie Chang; Erik A. Ranheim; et al.
Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component
Silvia Rasi; Valeria Spina; Alessio Bruscaggin; Tiziana Vaisitti; Claudio Tripodo; Francesco Forconi; Lorenzo De Paoli; Marco Fangazio; Elisa Sozzi; Emanuele Cencini; et al.
A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome
Takayuki Iwamoto; Giampaolo Bianchini; Yuan Qi; Massimo Cristofanilli; Anthony Lucci; Wendy A. Woodward; James M. Reuben; Junji Matsuoka; Yun Gong; Savitri Krishnamurthy; et al.
Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer
Lan V. Pham; Richard J. Ford
The role of BAFF-R dysregulation in B-lymphoid lineage malignancies
Lan V. Pham; Lingchen Fu; Archito T. Tamayo; Carlos Bueso-Ramos; Elias Drakos; Francisco Vega; L. Jeffrey Medeiros; Richard J. Ford
Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways
R. Saldova; J.M. Reuben; U.M. Abd Hamid; P.M. Rudd; M. Cristofanilli
Levels of specific serum N-glycans identify breast cancer patients with higher circulating tumor cell counts
Ashish Bains; Rajyalakshmi Luthra; L. Jeffrey Medeiros; Zhuang Zuo
FLT3 and NPM1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia
Keyur P. Patel; Farhad Ravandi; Deqin Ma; Abhaya Paladugu; Bedia A. Barkoh; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Acute myeloid leukemia with IDH1 or IDH2 mutation: Frequency and clinicopathologic features
Anupam Kumar; Hui Gao; Jia Xu; James Reuben; Dihua Yu; Kapil Mehta
Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells
Filip Janku; J. Jack Lee; Apostolia M. Tsimberidou; David S. Hong; Aung Naing; Gerald S. Falchook; Siqing Fu; Rajyalakshmi Luthra; Ignacio Garrido-Laguna; Razelle Kurzrock
PIK3CA mutations frequently coexist with ras and braf mutations in patients with advanced cancers
Aung Naing; James M. Reuben; Luis H. Camacho; Hui Gao; Bang-Ning Lee; Evan N. Cohen; Claire Verschraegen; Saneese Stephen; Joann Aaron; David Hong; et al.
Phase I dose escalation study of sodium stibogluconate (SSG), a protein tyrosine phosphatase inhibitor, combined with interferon alpha for patients with solid tumors
Aref Al-Kali; Srdan Verstovsek; Hagop Kantarjian; Rajyalakshmi Luthra; Jorge Cortes
Competing cell clones in myeloproliferative neoplasm
Lan V. Pham; Archito T. Tamayo; Changping Li; Carlos Bueso-Ramos; Richard J. Ford
An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas
Joan H. Admirand; Ronald J. Knoblock; Kevin R. Coombes; Constantine Tam; Ellen J. Schlette; William G. Wierda; Alessandra Ferrajoli; Susan O'Brien; Michael J. Keating; Rajyalakshmi Luthra; et al.
Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression
Zhuang Zuo; Dan Jones; Hui Yao; Deborah A. Thomas; Susan O'Brien; Farhad Ravandi; Hagop M. Kantarjian; Lynne V. Abruzzo; L Jeffrey Medeiros; Su S. Chen; et al.
A pathway-based gene signature correlates with therapeutic response in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
Cameron C. Yin; Jorge Cortes; John Galbincea; Neelima Reddy; Megan Breeden; Elias Jabbour; Rajyalakshmi Luthra; Dan Jones
Rapid clonal shifts in response to kinase inhibitor therapy in chronic myelogenous leukemia are identified by quantitation mutation assays
Ugo De Giorgi; Michal Mego; Eric M. Rohren; Ping Liu; Beverly C. Handy; James M. Reuben; Homer A. Macapinlac; Gabriel N. Hortobagyi; Massimo Cristofanilli; Naoto T. Ueno
18F-FDG PET/CT findings and circulating tumor cell counts in the monitoring of systemic therapies for bone metastases from breast cancer
Z. Chen; Y. Li; H. Zhang; P. Huang; R. Luthra
Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
Savitri Krishnamurthy; Massimo Cristofanilli; Balraj Singh; James Reuben; Hui Gao; Evan N. Cohen; Eleni Andreopoulou; Carolyn S. Hall; Ashutosh Lodhi; Summer Jackson; et al.
Detection of minimal residual disease in blood and bone marrow in early stage breast cancer
Bisrat G. Debeb; Xiaomei Zhang; Savitri Krishnamurthy; Hui Gao; Evan Cohen; Li Li; Angel A. Rodriguez; Melissa D. Landis; Anthony Lucci; Naoto T. Ueno; et al.
Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
Jonathan S. L. Earle; Rajyalakshmi Luthra; Angela Romans; Ronald Abraham; Joe Ensor; Hui Yao; Stanley R. Hamilton
Association of MicroRNA expression with microsatellite instability status in colorectal adenocarcinoma
Lan V. Pham; Archito T. Tamayo; Changping Li; William Bornmann; Waldemar Priebe; Richard J. Ford
Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: Therapeutic implications
Francisco Vega; Yogesh Davuluri; Jeong Hee Cho-Vega; Rajesh R. Singh; Shuguang Ma; Rui-Yu Wang; Asha S. Multani; Elias Drakos; Lan V. Pham; Yen-Chiu Lin Lee; et al.
Side population of a murine mantle cell lymphoma model contains tumour-initiating cells responsible for lymphoma maintenance and dissemination
Pei Lin; Rajyalakshmi Luthra; Roberto H. Nussenzveig; L. Jeffrey Medeiros
JAK2 V617F mutation is uncommon in patients with the 3q21q26 syndrome
Pranil Chandra; Rajyalakshmi Luthra; Zhuang Zuo; Hui Yao; Farhad Ravandi; Neeli Reddy; Guillermo Garcia-Manero; Hagop Kantarjian; Dan Jones
Acute myeloid leukemia with t(9;11)(p21-22;q23): Common properties of dysregulated Ras pathway signaling and genomic progression characterize de novo and therapy-related cases
R.R. Singh; J.E. Kim; Y. Davuluri; E. Drakos; J.H. Cho-Vega; H.M. Amin; F. Vega
Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation
James M. Reuben; Bang-Ning Lee; Changping Li; Hui Gao; Kristine R. Broglio; Vicente Valero; Summer A. Jackson; Naoto T. Ueno; Savitri Krishnamurthy; Gabriel N. Hortobagyi; et al.
Circulating tumor cells and biomarkers: Implications for personalized targeted treatments for metastatic breast cancer
Farhad Ravandi; Jorge E. Cortes; Daniel Jones; Stefan Faderl; Guillermo Garcia-Manero; Marina Y. Konopleva; Susan O'Brien; Zeev Estrov; Gautam Borthakur; Deborah Thomas; et al.
Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia
Rosa Lapalombella; Leslie Andritsos; Qing Liu; Sarah E. May; Rebekah Browning; Lan V. Pham; Kristie A. Blum; William Blum; Asha Ramanunni; Chelsey A. Raymond; et al.
Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway
Robert P. Hasserjian; Zhuang Zuo; Christine Garcia; Guilin Tang; Armen Kasyan; Rajyalakshmi Luthra; Lynne V. Abruzzo; Hagop M. Kantarjian; L. Jeffrey Medeiros; Sa A. Wang
Acute erythroid leukemia: A reassessment using criteria refined in the 2008 WHO classification
Bisrat G. Debeb; Wei Xu; Henry Mok; Li Li; Fredika Robertson; Naoto T. Ueno; Jim Reuben; Anthony Lucci; Massimo Cristofanilli; Wendy A. Woodward
Differential Radiosensitizing Effect of Valproic Acid in Differentiation Versus Self-Renewal Promoting Culture Conditions
U. De Giorgi; V. Valero; E. Rohren; M. Mego; G.V. Doyle; M.C. Miller; N.T. Ueno; B.C. Handy; J.M. Reuben; H.A. Macapinlac; et al.
Circulating tumor cells and bone metastases as detected by FDG-PET/CT in patients with metastatic breast cancer.
Ann H. Klopp; Lara Lacerda; Anshul Gupta; Bisrat G. Debeb; Travis Solley; Li Li; Erika Spaeth; Wei Xu; Xiaomei Zhang; Michael T. Lewis; et al.
Mesenchymal stem cells promote mammosphere formation and decrease E-Cadherin in normal and malignant breast cells
Anupam Kumar; Jia Xu; Samuel Brady; Hui Gao; Dihua Yu; James Reuben; Kapil Mehta
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells
Rajyalakshmi Luthra; Zhuang Zuo
COLD-PCR finds hot application in mutation analysis
M. Mego; U. De Giorgi; K. Broglio; S. Dawood; V. Valero; E. Andreopoulou; B. Handy; J.M. Reuben; M. Cristofanilli
Circulating tumour cells are associated with increased risk of venous thromboembolism in metastatic breast cancer patients
Alfonso Quintás-Cardama; Hagop Kantarjian; Taghi Manshouri; Rajyalakshmi Luthra; Zeev Estrov; Sherry Pierce; Mary Ann Richie; Gautam Borthakur; Marina Konopleva; Jorge Cortes; et al.
Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera
Arturo Vega-Ruiz; Jorge E. Cortes; Matjaz Sever; Taghi Manshouri; Alfonso Quintás-Cardama; Raja Luthra; Hagop M. Kantarjian; Srdan Verstovsek
Phase II study of imatinib mesylate as therapy for patients with systemic mastocytosis
Ji Eun Kim; Rajesh R Singh; Jeong Hee Cho-Vega; Elias Drakos; Yogesh Davuluri; Faisal A Khokhar; Luis Fayad; L Jeffrey Medeiros; Francisco Vega
Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-Cell lymphoma
Anthony Lucci; Savitri Krishnamurthy; Balraj Singh; Isabelle Bedrosian; Funda Meric-Bernstam; James Reuben; Kristine Broglio; Kailash Mosalpuria; Ashutosh Lodhi; Laura Vincent; et al.
Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow
Nitin Jain; James M. Reuben; Hagop Kantarjian; Changping Li; Hui Gao; Bang-Ning Lee; Evan N. Cohen; Theresa Ebarb; David A. Scheinberg; Jorge Cortes
Synthetic tumor-specific breakpoint peptide vaccine in patients with chronic myeloid leukemia and minimal residual disease: A phase 2 trial
Zhuang Zuo; Su S. Chen; Pranil K. Chandra; John M. Galbincea; Matthew Soape; Steven Doan; Bedia A. Barkoh; Hartmut Koeppen; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Application of COLD-PCR for improved detection of KRAS mutations in clinical samples
Circulating tumor cells and bone metastases as detected by FDG-PET/CT in patients with metastatic breast cancer
Ugo De Giorgi; Vicente Valero; Eric Rohren; Shaheenah Dawood; Naoto T. Ueno; M. Craig Miller; Gerald V. Doyle; Summer Jackson; Eleni Andreopoulou; Beverly C. Handy; et al.
Circulating tumor cells and [18F]fluorodeoxyglucose positron emission tomography/computed tomography for outcome prediction in metastatic breast cancer
Jing Lu; Patricia S. Steeg; Janet E. Price; Savitri Krishnamurthy; Sendurai A. Mani; James Reuben; Massimo Cristofanilli; Gabriela Dontu; Luc Bidaut; Vicente Valero; et al.
Breast cancer metastasis: Challenges and opportunities
Nitin Jain; Jorge Cortes; Alfonso Quintás-Cardama; Taghi Manshouri; Raja Luthra; Guillermo Garcia-Manero; Hagop Kantarjian; Srdan Verstovsek
Imatinib has limited therapeutic activity for hypereosinophilic syndrome patients with unknown or negative PDGFRα mutation status
Dipen M. Maru; Rajesh R. Singh; Christina Hannah; Constance T. Albarracin; Yong X. Li; Ronald Abraham; Angela M. Romans; Hui Yao; Madan G. Luthra; Sharmila Anandasabapathy; et al.
MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus
Steven A. Gustafson; Pei Lin; Su S. Chen; Lei Chen; Lynne V. Abruzzo; Rajyalakshmi Luthra; L. Jeffrey Medeiros; Sa A. Wang
Therapy-Related Acute Myeloid Leukemia With t(8;21) (q22;q22) Shares Many Features With De Novo Acute Myeloid Leukemia With t(8;21)(q22;q22) but Does Not Have a Favorable Outcome
C. Cameron Yin; Katherine I-Chun Lin; Rhett P. Ketterling; Ryan A. Knudson; L. Jeffrey Medeiros; Lynn L. Barron; Yang O. Huh; Rajyalakshmi Luthra; Michael J. Keating; Lynne V. Abruzzo
Chronic lymphocytic leukemia with t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated With atypical morphologic features and unmutated IgV H genes
William T. Shearer; Hans D. Ochs; Bang-Ning Lee; Evan N. Cohen; James M. Reuben; Irene Cheng; Bruce Thompson; Janet S. Butel; Antoine Blancher; Michel Abbal; et al.
Immune responses in adult female volunteers during the bed-rest model of spaceflight: Antibodies and cytokines
Dipen M. Maru; Rajyalakshmi Luthra; Arlene M. Correa; Jill White-Cross; Sharmila Anandasabapathy; Sunil Krishnan; Sushovan Guha; Ritsuko Komaki; Stephen G. Swisher; Jaffer A. Ajani; et al.
Frequent loss of heterozygosity of chromosome 1q in esophageal adenocarcinoma: Loss of chromosome 1q21.3 is associated with shorter overall survival
Rajesh R. Singh; Jeong Hee Cho-Vega; Yogesh Davuluri; Ma. Shuguang; Fatan Kasbidi; Cristiane Milito; Patrick A. Lennon; Elias Drakos; L. Jeffrey Medeiros; Rajyalakshmi Luthra; et al.
Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma
Julie E. Lang; Kailash Mosalpuria; Massimo Cristofanilli; Savitri Krishnamurthy; James Reuben; Balraj Singh; Isabelle Bedrosian; Funda Meric-Bernstam; Anthony Lucci
HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer
Rachel Sargent; Dan Jones; Lynne V. Abruzzo; Hui Yao; Jaime Bonderover; Marissa Cisneros; William G. Wierda; Michael J. Keating; Rajyalakshmi Luthra
Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia
Srdan Verstovsek; AyalewTefferi; Hagop Kantarjian; Taghi Manshouri; Raja Luthra; Animesh Pardanani; Alfonso Quintás-Cardama; Farhad Ravandi; Pat Ault; Carlos Bueso-Ramos; et al.
Alemtuzumab therapy for hypereosinophilic syndrome and chronic eosinophilic Leukemia
Lingchen Fu; Yen-Chiu Lin-Lee; Lan V. Pham; Archito T. Tamayo; Linda C. Yoshimura; Richard J. Ford
BAFF-R promotes cell proliferation and survival through interaction with IKKβ and NF-κB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells
A. Ferrajoli; S.M. O'Brien; S. Faderl; W.G. Wierda; J.M. Reuben; M.J. Keating
Lenalidomide: An emerging option in chronic lymphocytic leukemia
Dushyant Verma; Hagop M. Kantarjian; Dan Jones; Rajyalakshmi Luthra; Gautam Borthakur; Srdan Verstovsek; Mary Beth Rios; Jorge Cortes
Chronic myeloid leukemia (CML) with P190BCR-ABL: Analysis of characteristics, outcomes, and prognostic significance
M. Mego; U. De Giorgi; L. Hsu; N.T. Ueno; V. Valero; S. Jackson; E. Andreopoulou; S.-W. Kau; J.M. Reuben; M. Cristofanilli
Circulating tumor cells in metastatic inflammatory breast cancer
Malisha R. Johnson; Srdan Verstovsek; Jeffrey L. Jorgensen; T. Manshouri; Raja Luthra; Dan M. Jones; Carlos E. Bueso-Ramos; L. Jeffrey Medeiros; Yang O. Huh
Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow
Shannon N. Westin; Robin A. Lacour; Diana L. Urbauer; Rajyalakshmi Luthra; Diane C. Bodurka; Karen H. Lu; Russell R. Broaddus
Carcinoma of the lower uterine segment: A newly described association with Lynch syndrome
Dan Jones; Rajyalakshmi Luthra; Jorge Cortes; Deborah Thomas; Susan O'Brien; Carlos Bueso-Ramos; Seema Hai; Farhad Ravandi; Marcos De Lima; Hagop Kantarjian; et al.
BCR-ABL fusion transcript types and levels and their interaction with secondary genetic changes in determining the phenotype of Philadelphia chromosome positive leukemias
Massimo Cristofanilli; Savitri Krishnamurthy; Chandra M. Das; James M. Reuben; William Spohn; Jamileh Noshari; Frederick Becker; Peter R. Gascoyne
Dielectric cell separation of fine needle aspirates from tumor xenografts
R. Luthra; R.R. Singh; M.G. Luthra; Y.X. Li; C. Hannah; A.M. Romans; B.A. Barkoh; S.S. Chen; J. Ensor; D.M. Maru; et al.
MicroRNA-196a targets annexin A1: A microRNA-mediated mechanism of annexin A1 downregulation in cancers
Shaheenah Dawood; Kristine Broglio; Vicente Valero; James Reuben; Beverly Handy; Rabiul Islam; Summer Jackson; Gabriel N. Hortobagyi; Herbert Fritsche; Massimo Cristofanilli
Circulating tumor cells in metastatic breast cancer: From prognostic stratification to modification of the staging system?
Xin Shelley Wang; Qiuling Shi; Lori A. Williams; Charles S. Cleeland; Gary M. Mobley; James M. Reuben; Bang-Ning Lee; Sergio A. Giralt
Serum interleukin-6 predicts the development of multiple symptoms at nadir of allogeneic hematopoietic stem cell transplantation
Suraj K. George; R. Rajesh; Sunil Kumar S.; B. Sulekha; Prabha Balaram
A polyherbal ayurvedic drug - Indukantha Ghritha as an adjuvant to cancer chemotherapy via immunomodulation
Pei Lin; Lei Chen; Rajyalakshmi Luthra; Sergej N. Konoplev; Xuemei Wang; L. Jeffrey Medeiros
Acute myeloid leukemia harboring t(8;21)(q22;q22): A heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations
Yang O. Huh; Katherine I.-Chun Lin; Francisco Vega; Ellen Schlette; C. Cameron Yin; Michael J. Keating; R. Luthra; L. Jeffrey Medeiros; Lynne V. Abruzzo
MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis
Francisco Vega; Jeong Hee Cho-Vega; Patrick A. Lennon; Madan G. Luthra; Jaime Bailey; Megan Breeden; Dan Jones; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes
Alessandra Ferrajoli; Bang-Ning Lee; Ellen J. Schlette; Susan M. O'Brien; Hui Gao; Sijin Wen; William G. Wierda; Zeev Estrov; Stefan Faderl; Evan N. Cohen; et al.
Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
James M. Reuben; Savitri Krishnamurthy; Wendy Woodward; Massimo Cristofanilli
The role of circulating tumor cells in breast cancer diagnosis and prediction of therapy response
P.R. Molli; R.R. Singh; S.W. Lee; R. Kumar
MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene
Lan V. Pham; Hai-Jun Zhou; Yen-Chiu Lin-Lee; Archito T. Tamayo; Linda C. Yoshimura; Lingchen Fu; Bryant G. Darnay; Richard J. Ford
Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification
Ming Guo; Yun Gong; Michael Deavers; Elvio G. Silva; Jee Jan Yee; David E. Cogdell; Rajyalashmi Luthra; E. Lin; Cheng Lai Hung; Wei Zhang; et al.
Evaluation of a commercialized in situ hybridization assay for detecting human papillomavirus DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinoma
Massimo Cristofanilli; James Reuben; Jonathan Uhr
Circulating tumor cells in breast cancer: Fiction or reality?
M. Cristofanilli; P. Morandi; S. Krishnamurthy; J.M. Reuben; B.-N. Lee; D. Francis; D.J. Booser; M.C. Green; B.K. Arun; L. Pusztai; et al.
Imatinib mesylate (Gleevec®) in advanced breast cancer-expressing C-Kit or PDGFR-β: Clinical activity and biological correlations
Karen H. Lu; John O. Schorge; Kerry J. Rodabaugh; Molly S. Daniels; Charlotte C. Sun; Pamela T. Soliman; Kristin G. White; Rajyalakshmi Luthra; David M. Gershenson; Russell R. Broaddus
Prospective determination of prevalence of Lynch syndrome in young women with endometrial cancer
H.-Y. Yang; Y.-Y. Wen; Y.-L. Lin; L. Pham; C.-H. Su; H. Yang; J. Chen; M.-H. Lee
Roles for negative cell regulator 14-3-3σ in control of MDM2 activities
Hai-Jun Zhou; Lan V. Pham; Archito T. Tamayo; Yen-Chiu Lin-Lee; Lingchen Fu; Linda C. Yoshimura; Richard J. Ford
Nuclear CD40 interacts with c-Rel and enhances proliferation in aggressive B-cell lymphoma
Rajesh R. Singh; Rakesh Kumar
MTA family of transcriptional metaregulators in mammary gland morphogenesis and breast cancer
Lynne V. Abruzzo; Lynn L. Barron; Keith Anderson; Rachel J. Newman; William G. Wierda; Susan O'Brien; Alessandra Ferrajoli; Madan Luthra; Sameer Talwalkar; Rajyalakshmi Luthra; et al.
Identification and validation of biomarkers of IgVH mutation status in chronic lymphocytic leukemia using microfluidics quantitative real-time polymerase chain reaction technology
Julie G. Izzo; Usha Malhotra; Tsung-Teh Wu; Rajalakshmi Luthra; Arlene M. Correa; Stephen G. Swisher; Wayne Hofstetter; K. S. Clifford Chao; Mien-Chie Hung; Jaffer A. Ajani
Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-κB expression
Richard J. Ford; Long Shen; Yen Chiu Lin-Lee; Lan V. Pham; Asha Multani; Hai-Jun Zhou; Archito T. Tamayo; ChongJie Zhang; Lesleyann Hawthorn; John K. Cowell; et al.
Development of a murine model for blastoid variant mantle-cell lymphoma
Filippo Acconcia; Christopher J. Barnes; Rajesh R. Singh; Amjad H. Talukder; Rakesh Kumar
Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase
Julie G. Izzo; Rajyalakshmi Luthra; Tseung-Teh Wu; Arlene M. Correa; Madan Luthra; Sharmila Anandasabapathy; K.S. Clifford Chao; Mien-Chie Hung; Bharat Aggarwal; Walter N. Hittelman; et al.
Molecular Mechanisms in Barrett's Metaplasia and Its Progression
Julie G. Izzo; Tsung-Teh Wu; Xifeng Wu; Joe Ensor; Rajyalakshmi Luthra; Jennifer Pan; Arlene Correa; Stephen G. Swisher; Clifford K.S. Chao; Walter N. Hittelman; et al.
Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma
William T. Shearer; Shaojie Zhang; James M. Reuben; Bang-Ning Lee; Janet S. Butel
Predictors of immune function in space flight
Madan G. Luthra; Jaffer A. Ajani; Julie Izzo; Joe Ensor; Tsung-Teh Wu; Asif Rashid; Li Zhang; Alexandria Phan; Norio Fukami; Rajyalakshmi Luthra
Decreased expression of gene cluster at chromosome 1q21 defines molecular subgroups of chemoradiotherapy response in esophageal cancers
Ming Guo; Nour Sneige; Elvio G. Silva; Yee Jee Jan; David E. Cogdell; E. Lin; Rajyalakshmi Luthra; Wei Zhang
Distribution and viral load of eight oncogenic types of human papillomavirus (HPV) and HPV 16 integration status in cervical intraepithelial neoplasia and carcinoma
Massimo Cristofanilli; Kristine R. Broglio; Valentina Guarneri; Summer Jackson; Herbert A. Fritsche; Rabiul Islam; Shaheenah Dawood; James M. Reuben; Shu-Wan Kau; Juanita M. Lara; et al.
Circulating tumor cells in metastatic breast cancer: Biologic staging beyond tumor burden
C. Cameron Yin; L. Jeffrey Medeiros; Candy C. Cromwell; Ashwini P. Mehta; Pei Lin; Rajyalakshmi Luthra; Lynne V. Abruzzo
Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma
Rajyalakshmi Luthra; Madan G. Luthra; Julie Izzo; Tsung-Teh Wu; Enrique Lopez-Alvarez; Usha Malhotra; In Seon Choi; Li Zhang; Jaffer A. Ajani
Biomarkers of Response to Preoperative Chemoradiation in Esophageal Cancers
Daniel G. Rosen; Kathy Q. Cai; Rajyalakshmi Luthra; Jinsong Liu
Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma
Jennifer Sims-Mourtada; Julie G. Izzo; Smith Apisarnthanarax; Tsung-Teh Wu; Usha Malhotra; Rajyalashmi Luthra; Zhongxing Liao; Ritsuko Komaki; Albert Van Der Kogel; Jaffer Ajani; et al.
Hedgehog: An attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response
Julie G. Izzo; Arlene M. Correa; Tsung-Teh Wu; Usha Malhotra; Clifford K.S. Chao; Rajyalakshmi Luthra; Joe Ensor; Alexander Dekovich; Zhongxing Liao; Walter N. Hittelman; et al.
Pretherapy nuclear factor-κB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma
Hao Zhang; Rajesh R. Singh; Amjad H. Talukder; Rakesh Kumar
Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway
E. Jabbour; H. Kantarjian; D. Jones; M. Talpaz; N. Bekele; S. O'Brien; X. Zhou; R. Luthra; G. Garcia-Manero; F. Giles; et al.
Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate
Martin Körbling; James M. Reuben; Hui Gao; Bang-Ning Lee; David M. Harris; David Cogdell; Sergio A. Giralt; Issa F. Khouri; Rima M. Saliba; Richard E. Champlin; et al.
Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: A novel blood cell component for therapeutic vasculogenesis
Pei Lin; Dan Jones; L. Jeffrey Medeiros; Weina Chen; Francisco Vega-Vazquez; Rajyalakshmi Luthra
Activating FLT3 mutations are detectable in chronic and blast phases of chronic myeloproliferative disorders other than chronic myeloid leukemia
Bang-Ning Lee; Michele Follen; Graciela Rodriquez; De-Yu Shen; Anais Malpica; William T. Shearer; James M. Reuben
Deficiencies in myeloid antigen-presenting cells in women with cervical squamous intraepithelial lesions
Solution structure and antiestrogenic activity of the unique C-terminal, NR-box motif-containing region of MTA1s
Yen-Chiu Lin-Lee; Lan V. Pham; Archito T. Tamayo; Lingchen Fu; Hai-Jun Zhou; Linda C. Yoshimura; Glenn L. Decker; Richard J. Ford
Nuclear localization in the biology of the CD40 receptor in normal and neoplastic human B lymphocytes
Rajesh R. Singh; Anupama E. Gururaj; Ratna K. Vadlamudi; Rakesh Kumar
9-cis-retinoic acid up-regulates expression of transcriptional coregulator PELP1, a novel coactivator of the retinoid X receptor α pathway
James M. Reuben; Bang-Ning Lee; Changping Li; Jesus Gomez-Navarro; Viviana A. Bozon; Charla A. Parker; Ingrid M. Hernandez; Carolina Gutierrez; Gabriel Lopez-Berestein; Luis H. Camacho
Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma
Lingchen Fu; Yen-Chiu Lin-Lee; Lan V. Pham; Archito Tamayo; Linda Yoshimura; Richard J. Ford
Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas
C.H. Yang; A.M. Gonzalez-Angulo; J.M. Reuben; D.J. Booser; L. Pusztai; S. Krishnamurthy; D. Esseltine; J. Stec; K.R. Broglio; R. Islam; et al.
Bortezomib (VELCADE®) in metastatic breast cancer: Pharmacodynamics, biological effects, and prediction of clinical benefits
MTA1, a transcriptional activator of breast cancer amplified sequence 3
J.P. Cata; H.-R. Weng; B.N. Lee; J.M. Reuben; P.M. Dougherty
Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy
Julie G. Izzo; Usha Malhotra; Tsung-Teh Wu; Joe Ensor; Rajyalakshmi Luthra; Jeffrey H. Lee; Stephen G. Swisher; Zhongxing Liao; K.S. Clifford Chao; Walter N. Hittelman; et al.
Association of activated transcription factor nuclear factor κB with chemoradiation resistance and poor outcome in esophageal carcinoma
Rajyalakshmi Luthra; Tsung-Teh Wu; Madan G. Luthra; Julie Izzo; Enrique Lopez-Alvarez; Li Zhang; Jaime Bailey; Jeffrey H. Lee; Robert Bresalier; Asif Rashid; et al.
Gene expression profiling of localized esophageal carcinomas: Association with pathologic response to preoperative chemoradiation
Russell R. Broaddus; Henry T. Lynch; Lee-May Chen; Molly S. Daniels; Peggy Conrad; Mark F. Munsell; Kristin G. White; Rajyalakshmi Luthra; Karen H. Lu
Pathologic features of endometrial carcinoma associated with HNPCC: A comparison with sporadic endometrial carcinoma
K.-H. Chang; C. Albarracin; R. Luthra; L. Wang; W. Zheng; A. Malpica; M.T. Deavers; E.G. Silva; J. Liu
Discordant genetic changes in ovarian and endometrial endometrioid carcinomas: A potential pitfall in molecular diagnosis
Rajyalakshmi Luthra; L Jeffrey Medeiros
TaqMan reverse transcriptase-polymerase chain reaction coupled with capillary electrophoresis for quantification and identification of bcr-abl transcript type.
Lan V. Pham; Archito T. Tamayo; Linda C. Yoshimura; Yen-Chiu Lin-Lee; Richard J. Ford
Constitutive NF-κB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
Rajesh R. Singh; Christopher J. Barnes; Amjad H. Talukder; Suzanne A. W. Fuqua; Rakesh Kumar
Negative regulation of estrogen receptor α transactivation functions by LIM domain only 4 protein
H. Gao; B.-N. Lee; M. Talpaz; N.J. Donato; J.E. Cortes; H.M. Kantarjian; J.M. Reuben
Imatinib mesylate suppresses cytokine synthesis by activated CD4 T cells of patients with chronic myelogenous leukemia
Steroid hormone receptor signaling in tumorigenesis
Weina Chen; Dan Jones; L. Jeffrey Medeiros; Rajyalashmi Luthra; Pei Lin
Acute myeloid leukaemia with FLT3 gene mutations of both internal tandem duplication and point mutation type
Ratna K. Vadlamudi; Bramanandam Manavathi; Rajesh R. Singh; Diep Nguyen; Feng Li; Rakesh Kumar
An essential role of Pak1 phosphorylation of SHARP in Notch signaling
C. Cameron Yin; Armand B. Glassman; Pei Lin; Jose R. Valbuena; Dan Jones; Rajyalakshmi Luthra; L. Jeffrey Medeiros
Morphologic, cytogenetic, and molecular abnormalities in therapy-related acute promyelocytic leukemia
Effects of radiation and latent virus on immune responses in a space flight model
Rajesh R. Singh; Chunying Song; Zhibo Yang; Rakesh Kumar
Nuclear localization and chromatin targets of p21-activated kinase 1
Roberto Rangel; Morgan R. McKeller; Jennifer C. Sims-Mourtada; Cristina Kashi; Kelly Cain; Eric D. Wieder; Jeffrey J. Molldrem; Lan V. Pham; Richard J. Ford; Patricia Yotnda; et al.
Assembly of the κ PreB receptor requires a Vκ-like protein encoded by a germline transcript
Jorge Cortes; Moshe Talpaz; Susan O'Brien; Dan Jones; Rajyalakshmi Luthra; Jenny Shan; Francis Giles; Stefan Faderl; Srdan Verstovsek; Guillermo Garcia-Manero; et al.
Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
Massimo Cristofanilli; Daniel F. Hayes; G. Thomas Budd; Mathew J. Ellis; Alison Stopeck; James M. Reuben; Gerald V. Doyle; Jeri Matera; W. Jeffrey Allard; M. Craig Miller; et al.
Circulating tumor cells: A novel prognostic factor for newly diagnosed metastatic breast cancer
Antoni Ribas; Luis H. Camacho; Gabriel Lopez-Berestein; Dmitri Pavlov; Cecile A. Bulanhagui; Robert Millham; Begoña Comin-Anduix; James M. Reuben; Elisabeth Seja; Charla A. Parker; et al.
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
Constance T. Albarracin; Elvio G. Silva; Anais Malpica; Rajalakshmi Luthra; Jinsong Liu
The role of hMSH3 and hMSH6 in ovarian endometrioid carcinoma and relationship with microsatellite instability phenotype
Alex Bowman; Dan Jones; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Quantitative PCR detection of t(14;18) bcl-2/JH fusion sequences in follicular lymphoma patients: Comparison of peripheral blood and bone marrow aspirate samples
Hagop M. Kantarjian; Jorge E. Cortes; Susan O'Brien; Rajyalakshmi Luthra; Francis Giles; Srdan Verstovsek; Stefan Faderl; Deborah Thomas; Guillermo Garcia-Manero; Mary Beth Rios; et al.
Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome-positive chronic-phase chronic myeloid leukemia after failure of interferon-α
Erika Resetkova; Ana M. Gonzalez-Angulo; Nour Sneige; Timothy J. Mcdonnell; Aman U. Buzdar; Shu Wan Kau; Yuko Yamamura; James M. Reuben; Gabriel N. Hortobagyi; Massimo Cristofanilli
Prognostic value of P53, MDM-2, and MUC-1 for patients with inflammatory breast carcinoma
Mauricio P. Oyarzo; Pei Lin; Armand Glassman; Carlos E. Bueso-Ramos; Rajyalakshmi Luthra; L. Jeffrey Medeiros
Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations
Massimo Cristofanilli; G. Thomas Budd; Matthew J. Ellis; Alison Stopeck; Jeri Matera; M. Craig Miller; James M. Reuben; Gerald V. Doyle; W. Jeffrey Allard; Leon W.M.M. Terstappen; et al.
Circulating tumor cells, disease progression, and survival in metastatic breast cancer
Dan Jones; Sherif Ibrahim; Kaushali Patel; Rajyalakshmi Luthra; Madeleine Duvic; L. Jeffrey Medeiros
Degree of CD25 expression in T-cell lymphoma is dependent on tissue site: Implications for targeted therapy
Russell R. Broaddus; Patrick M. Lynch; Karen H. Lu; Raja Luthra; Sara J. Michelson
Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome
Rajyalakshmi Luthra; L. Jeffrey Medeiros
Isothermal multiple displacement amplification: A highly reliable approach for generating unlimited high molecular weight genomic DNA from clinical specimens
Sandip K. Mishra; Amjad H. Talukder; Anupama E. Gururaj; Zhibo Yang; Rajesh R. Singh; My G. Mahoney; Clara Francí; Ratna K. Vadlamudi; Rakesh Kumar
Upstream determinants of estrogen receptor-α regulation of metastatic tumor antigen 3 pathway
James M Reuben; Martin Korbling; Hui Gao; Bang-Ning Lee
The effect of low dose gamma irradiation on the differentiation and maturation of monocyte derived dendritic cells.
Shailendra Mundhada; Rajyalakshmi Luthra; Pedro Cano
Association of HLA class I and class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)
David K. McGregor; Tsung-Teh Wu; Asif Rashid; Rajyalakshmi Luthra; Stanley R. Hamilton
Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability
Miloslav Beran; Rajyalakshmi Luthra; Hagop Kantarjian; Elihu Estey
FLT3 mutation and response to intensive chemotherapy in young adult and elderly patients with normal karyotype
Kathy Qi Cai; Constance Albarracin; Daniel Rosen; Rocksheng Zhong; Wenxin Zheng; Rajyalakshmi Luthra; Russell Broaddus; Jinsong Liu
Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma
Alok C. Bharti; Shishir Shishodia; James M. Reuben; Donna Weber; Raymond Alexanian; Saroj Raj-Vadhan; Zeev Estrov; Moshe Talpaz; Bharat B. Aggarwal
Nuclear factor-κB and STAT3 are constitutively active in CD138 + cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis
Bang-Ning Lee; Michele Follen; De-Yu Shen; Anais Malpica; Karen Adler-Storthz; William T. Shearer; James M. Reuben
Depressed Type 1 Cytokine Synthesis by Superantigen-Activated CD4 + T Cells of Women with Human Papillomavirus-Related High-Grade Squamous Intraepithelial Lesions
Lajos Pusztai; Tito R. Mendoza; James M. Reuben; Monica M. Martinez; Jie S. Willey; Juanita Lara; Abdul Syed; Herbert A. Fritsche; Eduardo Bruera; Daniel Booser; et al.
Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy
R. Rajesh Singh; Jui-Yoa Chang
Investigating conformational stability of bovine pancreatic phospholipase A2: A novel concept in evaluating the contribution of the 'native framework' of disulphides to the global conformational stability of proteins
Rajyalakshmi Luthra; Beatriz Sanchez-Vega; L. Jeffrey Medeiros
TaqMan RT-PCR assay coupled with capillary electrophoresis for quantification and identification of bcr-abl transcript type
Jinsong Liu; Constance T. Albarracin; Ki-Hong Chang; Jennifer A. Thompson-Lanza; Wenxin Zheng; David M. Gershenson; Russell Broaddus; Rajyalakshmi Luthra
Microsatellite instability and expression of hMLH1 and hMSH2 proteins in ovarian endometrioid cancer
Bang-Ning Lee; Robert Dantzer; Keith E. Langley; Gary J. Bennett; Patrick M. Dougherty; Adrian J. Dunn; Christina A. Meyers; Andrew H. Miller; Richard Payne; James Reuben; et al.
A cytokine-based neuroimmunologic mechanism of cancer-related symptoms
Shi-Nian Cao; Ki-Hong Chang; Rajyalakshmi Luthra; Jinsong Liu
Frameshift Mutations in the Bax Gene Are Not Involved in Development of Ovarian Endometrioid Carcinoma
Structural stability of human α-thrombin studied by disulfide reduction and scrambling
R. Rajesh Singh; Jui Yoa Chang
Structural stability of human alpha-thrombin studied by disulfide reduction and scrambling.
Simona Gatto; Barbara Scappini; Lan Pham; Francesco Onida; Michele Milella; Greg Ball; Clara Ricci; Vladimir Divoky; Srdan Verstovsek; Hagop M. Kantarjian; et al.
The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr/Abl-positive cell lines sensitive and resistant to imatinib mesylate
Lan V. Pham; Archito T. Tamayo; Linda C. Yoshimura; Piao Lo; Richard J. Ford
Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
Charles S. Cleeland; Gary J. Bennett; Robert Dantzer; Patrick M. Dougherty; Adrian J. Dunn; Christina A. Meyers; Andrew H. Miller; Richard Payne; James M. Reuben; Xin Shelley Wang; et al.
Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms
Hatice Duzkale; Lance C. Pagliaro; Michael G. Rosenblum; Ali Varan; Baoshun Liu; James Reuben; William G. Wierda; Martin Korbling; John D. McMannis; Armand B. Glassman; et al.
Bone marrow purging studies in acute myelogenous leukemia using the recombinant anti-CD33 immunotoxin HuM195/rGel
George Adrian Calin; Steliana Calin; Radu Ionescu; Marian Croitoru; Mircea Diculescu; Alexandru Oproiu
Successful local fibrinolytic treatment and balloon angioplasty in superior mesenteric arterial embolism: A case report and literature review
Gloria N. Mattiuzzi; Jorge E. Cortes; Moshe Talpaz; James Reuben; Mary Beth Rios; Jianjin Shan; Dimitrios Kontoyiannis; Francis J. Giles; Issam Raad; Srdan Verstovsek; et al.
Development of Varicella-Zoster virus infection in patients with chronic myelogenous leukemia treated with imatinib mesylate
Xiang Y. Han; Audrey S. Pham; Jeffrey J. Tarrand; Pramila K. Sood; Rajyalakshmi Luthra
Rapid and accurate identification of mycobacteria by sequencing hypervariable regions of the 16S ribosomal RNA gene
Francisco Vega; Rajyalakshmi Luthra; L. Jeffrey Medeiros; Valerie Dunmire; Sang-Joon Lee; Madeleine Duvic; Dan Jones
Clonal heterogeneity in mycosis fungoides and its relationship to clinical course
Beatriz Sanchez-Vega; Francisco Vega; L. Jeffrey Medeiros; Ming S. Lee; Rajyalakshmi Luthra
Quantification of bcl-2/JH fusion sequences and a control gene by multiplex real-time PCR coupled with automated amplicon sizing by capillary electrophoresis
Vilmos A. Thomázy; Rajyalakshmi Luthra; Margaret O. Uthman; Peter J.A. Davies; L. Jeffrey Medeiros
Determination of cyclin D1 and CD20 mRNA levels by real-time quantitative RT-PCR from archival tissue sections of mantle cell lymphoma and other non-Hodgkin's lymphomas
James M. Reuben; Bang-Ning Lee; Mary Paul; Mark W. Kline; Stanley G. Cron; Stuart Abramson; Dorothy Lewis; Claudia A. Kozinetz; William T. Shearer
Magnitude of IFN-γ production in HIV-1-infected children is associated with virus suppression
R.Rajesh Singh; A.G. Appu Rao
Reductive unfolding and oxidative refolding of a Bowman-Birk inhibitor from horsegram seeds (Dolichos biflorus): Evidence for 'hyperreactive' disulfide bonds and rate-limiting nature of disulfide isomerization in folding
W.T. Shearer; J.S. Butel; J.M. Reuben; D.S. Gridley; R.J. White; R. Gerzer
Spaceflight conditions alter human immunity and predispose to infection and cancer 2nd joint conference of the IEEE engineering in medicine and biology society and the biomedical engineering society
William T. Shearer; Muhammad Rais; Jose M. Teran; Stuart L. Abramson; Pim Y. Brouwers; Karen D. Evankovich; Daniel G. Glaze; Larry S. Jefferson; Dan K. Seilheimer; E. O'Brian Smith; et al.
sTNF-αRI levels in childhood asthma
Wareef Kabbani; Patrick S. Houlihan; Rajayalaksh Luthra; Stanley R. Hamilton; Asif Rashid
Mucinous and nonmucinous appendiceal adenocarcinomas: Different clinicopathological features but similar genetic alterations
Lan V Pham; Archito T Tamayo; Linda C Yoshimura; Piao Lo; Nicholas Terry; Pamela S Reid; Richard J Ford
A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-κB and autonomous cell growth in B cell lymphomas
L. Jeffrey Medeiros; Seema Hai; Vilmos A. Thomazy; Oscar C. Estalilla; Jorge Romaguera; Rajyalakshmi Luthra
Real-time RT-PCR assay for quantifying cyclin D1 mRNA in B-cell non-Hodgkin's lymphomas
Lynne V. Abruzzo; Cecilia M. Rosales; L. Jeffrey Medeiros; Francisco Vega; Rajyalakshmi Luthra; John T. Manning; Michael J. Keating; Dan Jones
Epstein-Barr virus-positive B-cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-cell neoplasms
Beatriz Sanchez-Vega; Francisco Vega; Seema Hai; L. Jeffrey Medeiros; Rajyalakshmi Luthra
Real-time t(14;18)(q32;q21) PCR assay combined with high-resolution capillary electrophoresis: A novel and rapid approach that allows accurate quantitation and size determination of bcl-2/JH fusion sequences
William T. Shearer; Bang-Ning Lee; Stanley G. Cron; Howard M. Rosenblatt; E.O'Brian Smith; Desmond J. Lugg; Peter M. Nickolls; Robert M. Sharp; Karl Rollings; James M. Reuben
Suppression of human anti-inflammatory plasma cytokines IL-10 and IL-1RA with elevation of proinflammatory cytokine IFN-γ during the isolation of the Antarctic winter
Francisco Vega; L. Jeffrey Medeiros; Dan Jones; Lynne V. Abruzzo; Raymond Lai; John Manning; Valerie Dunmire; Rajyalakshmi Luthra
A novel four-color PCR assay to assess T-cell receptor gamma gene rearrangements in lymphoproliferative lesions
Di Lu; Madeleine Duvic; L. Jeffrey Medeiros; Rajyalakshmi Luthra; David M. Dorfman; Dan Jones
The T-Cell Chemokine Receptor CXCR3 Is Expressed Highly in Low-Grade Mycosis Fungoides
Marsha L. Frazier; Frederick T. O'Donnell; Shouming Kong; Xiangjun Gu; Imelda Campos; Rajyalakshmi Luthra; Patrick M. Lynch; Christopher I. Amos
Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes
E. Olsen; M. Duvic; A. Frankel; Y. Kim; A. Martin; E. Vonderheid; B. Jegasothy; G. Wood; M. Gordon; P. Heald; et al.
Pivotal phase III trial of two dose levels of denileukin diftitox for the treatment of cutaneous T-cell lymphoma
James V. Bruckner; Glenna M. Kyle; Raja Luthra; Daniel Acosta; Sanjay M. Mehta; Sankar Sethuraman; Srinivasa Muralidhara
Acute, short-term, and subchronic oral toxicity of 1,1,1-trichloroethane in rats
William T. Shearer; Desmond J. Lugg; Howard M. Rosenblatt; Peter M. Nickolls; Robert M. Sharp; James M. Reuben; Hans D. Ochs
Antibody responses to bacteriophage φX-174 in human subjects exposed to the Antarctic winter-over model of spaceflight
William T. Shearer; James M. Reuben; Janet M. Mullington; Nicholas J. Price; Bang-Ning Lee; E.O'Brian Smith; Martin P. Szuba; Hans P.A. Van Dongen; David F. Dinges
Soluble TNF-α receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight
Luis Fayad; Michael J. Keating; James M. Reuben; Susan O'Brien; Bang-Ning Lee; Susan Lerner; Razelle Kurzrock
Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: Correlation with phenotypic characteristics and outcome
F. Vega; L.J. Medeiros; C. Bueso-Ramos; D. Jones; R. Lai; R. Luthra; L.V. Abruzzo
Hepatosplenic gamma/delta T-cell lymphoma in bone marrow: A sinusoidal neoplasm with blastic cytologic features
Bang-Ning Lee; Hunter Hammill; Edwina J. Popek; Stanley Cron; Claudia Kozinetz; Mary Paul; William T. Shearer; James M. Reuben
Production of interferons and β-chemokines by placental trophoblasts of HIV-1-infected women
John L. Fahey; Najib Aziz; John Spritzler; Susan Plaeger; Parunag Nishanian; Janet L. Lathey; Joan Seigel; Alan L. Landay; Rakhi Kilarui; John L. Schmitz; et al.
Need for an external proficiency testing program for cytokines, chemokines, and plasma markers of immune activation
Oscar C. Estalilla; L. Jeffrey Medeiros; John T. Manning Jr.; Rajyalakshmi Luthra
5' → 3' Exonuclease-based real-time PCR assays for detecting the t(14;18)(q32;21): A survey of 162 malignant lymphomas and reactive specimens
James M. Reuben; Bang-Ning Lee; Hannah Johnson; Herbert Fritsche; Hagop M. Kantarjian; Moshe Talpaz
Restoration of Th1 cytokine synthesis by T cells of patients with chronic myelogenous leukemia in cytogenetic and hematologic remission with interferon-α
Jerry Bryant; Lan Pham; Linda Yoshimura; Archito Tamayo; Nelson Ordonez; Richard J. Ford
Development of intermediate-grade (mantle cell) and low-grade (small lymphocytic and marginal zone) human non-Hodgkin's lymphomas xenotransplanted in severe combined immunodeficiency mouse models
Nora M. Navone; Maria Del C. Rodriguez-Vargas; William F. Benedict; Patricia Troncoso; Timothy J. McDonnell; Jaim-Hua Zhou; Rajyalakshmi Luthra; Christopher J. Logothetis
TabBO: A model reflecting common molecular features of androgen- independent prostate cancer
Shouming Kong; Christopher I. Amos; Rajyalakshmi Luthra; Patrick M. Lynch; Bernard Levin; Marsha L. Frazier
Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer
R. Luthra; L.J. Medeiros
5' → 3' Exonuclease-based real-time PCR methods for detecting the t(14;18) and t(11;14) in non-Hodgkin's lymphomas
R.L. Katz; N.P. Caraway; J. Gu; F. Jiang; L.A. Pasco-Miller; A.B. Glassman; R. Luthra; K.J. Hayes; J.E. Romaguera; F.F. Cabanillas; et al.
Detection of chromosome 11q13 breakpoints by interphase fluorescence in situ hybridization: A useful ancillary method for the diagnosis of mantle cell lymphoma
Bang-Ning Lee; Michele Follen; Guillermo Tortolero-Luna; Nancy Eriksen; Andrew Helfgott; Hunter Hammill; William T. Shearer; James M. Reuben
Synthesis of IFN-γ by CD8+ T cells is preserved in HIV-infected women with HPV-related cervical squamous intraepithelial lesions
Gideon Steinbach; Richard Ford; Gary Glober; Dory Sample; Frederick B. Hagemeister; Patrick M. Lynch; Peter W. McLaughlin; Maria A. Rodriguez; Jorge E. Romaguera; Andreas H. Sarris; et al.
Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue: An uncontrolled trial
George Calin; Juul Wijnen; Heleen Van Der Klift; Ana Ionita; Adri Mulder; Cor Breukel; Ron Smits; Hans Dauwerse; Kerstin Hansson; Steliana Calin; et al.
Marfan-like habitus and familial adenomatous polyposis in two unrelated males: A significant association?
M.L. Frazier; F.A. Sinicrope; C.I. Amos; K.R. Cleary; P.M. Lynch; B. Levin; R. Luthra
Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer.
Bogdan Czerniak; Vijaya Chaturvedi; Li Li; Sherie Hodges; Dennis Johnston; Jae Y. Ro; Rajyalakshmi Luthra; Christopher Logothetis; Andrew C. Von Eschenbach; H. Barton Grossman; et al.
Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: Implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer
Rajyalakshmi Luthra; Andreas H. Sarris; Seema Hai; Abhaya V. Paladugu; Jorge E. Romaguera; Fernando F. Cabanillas; L. Jeffrey Medeiros
Real-time 5' → 3' exonuclease-based PCR assay for detection of the t(11;14)(q13;q32)
Bang-Ning Lee; Madeleine Duvic; Chih-Kwang Tang; Carlos Bueso-Ramos; Zeev Estrov; James M. Reuben
Dysregulated synthesis of intracellular type 1 and type 2 cytokines by T cells of patients with cutaneous T-cell lymphoma
Rajyalakshmi Luthra; J. Adelia McBride; Fernando Cabanillas; Andreas Sarris
Novel 5' exonuclease-based real-time PCR assay for the detection of t(14;18)(q32;q21) in patients with follicular lymphoma
C.F. LeMaistre; Mansoor N. Saleh; Timothy M. Kuzel; Francine Foss; Leonidas C. Platanias; Gary Schwartz; Mark Ratain; Alain Rook; Cesar O. Freytes; Fiona Craig; et al.
Phase I trial of a ligand fusion-protein (DAB389IL-2) in lymphomas expressing the receptor for interkeukin-2
Andreas H. Sarris; Rajyalakshmi Luthra; Fernando Cabanillas; Stephan W. Morris; William C. Pugh
Genomic DNA amplification and the detection of t(2;5)(p23;q35) in lymphoid neoplasms
Robert S. Wallis; Howard M. Lederman; John Spritzler; Jennifer L. Devers; Daniel Georges; Adriana Weinberg; Susan Stehn; Michael M. Lederman; R.P. Bucy; A. Craiu; et al.
Measurement of induced cytokines in AIDS clinical trials using whole blood: A preliminary report
M.N. Saleh; C.F. LeMaistre; T.M. Kuzel; F. Foss; L.C. Platanias; G. Schwartz; M. Ratain; A. Rook; C.O. Freytes; F. Craig; et al.
Antitumor activity of DAB389IL-2 fusion toxin in mycosis fungoides
R. Luthra; W.C. Pugh; M. Waasdorp; W. Morris; F. Cabanillas; P.K. Chan; A.H. Sarris
Mapping of genomic t(2;5)(p23;q35) break points in patients with anaplastic large cell lymphoma by sequencing long-range PCR products
J. Reuben; B.-N. Lee; E.J. Popek
HIV and the placenta
W.T. Shearer; J. Reuben; B.N. Lee; E.J. Popek; D.E. Lewis; H.H. Hammill; I.C. Hanson; M.W. Kline; C. Langston
Role of placental cytokines and inflammation in vertical transmission of HIV infection.
Bang-Ning Lee; Nelson Ordonez; Edwina J. Popek; Jian-Guo Lu; Andrew Helfgott; Nancy Eriksen; Hunter Hammill; Claudia Kozinetz; Marilyn Doyle; Mark Kline; et al.
Inflammatory cytokine expression is correlated with the level of human immunodeficiency virus (HIV) transcripts in HIV-infected placental trophoblastic cells
R. Luthra; J.A. McBride; S. Hai; F. Cabanillas; W.C. Pugh
The application of fluorescence-based PCR and PCR-SSCP to monitor the clonal relationship of cells bearing the t(14;18)(q32;q21) in sequential biopsy specimens from patients with follicle center cell lymphoma
Bang-Ning Lee; Jian-Guo Lu; De-Yu Shen; Stephen Li; William T. Shearer; James M. Reuben
Quantification of IL-2 and IL-2 receptor mRNA in peripheral blood mononuclear cells by the RT-PCR based SHARP Signal system
W.T. Shearer; J. Reuben; B.-N. Lee; E.J. Popek; D.E. Lewis; H.H. Hammill; I.C. Hanson; M.W. Kline; C. Langsten
Role of placental cytokines and inflammation in vertical transmission of HIV infection
Marilyn Doyle; Gloria P. Heresi; Enrique Caceres; Jane T. Atkins; James Reuben
Pneumocystis carinii pneumonia in infants who were exposed to human immunodeficiency virus but were not infected: An exception to the AIDS surveillance case definition
A.H. Sarris; R. Luthra; V. Papadimitracopoulou; M. Waasdorp; M.A. Dimopoulos; J.A. McBride; F. Cabanillas; M. Duvic; A. Deisseroth; S.W. Morris; et al.
Long-range amplification of genomic DNA detects the t(2;5)(p23;q35) in anaplastic large-cell lymphoma, but not in other non-Hodgkin's lymphomas, Hodgkin's disease, or lymphomatoid papulosis
James M. Reuben; Jim A. Turpin; Bang-Ning Lee; Marilyn Doyle; Bernard Gonik; Robert Jacobson; William T. Shearer
Induction of inflammatory cytokines in placental monocytes of gravidae infected with the human immunodeficiency virus type 1
Andreas H. Sarris; Rajyalakshmi Luthra; Valli Papadimitracopoulou; Mimi Waasdorp; Meletios A. Dimopoulos; J.A. McBride; Fernando Cabanillas; Madeleine Duvic; Albert Deisseroth; Stephan W. Morris; et al.
Amplification of genomic DNA demonstrates the presence of the t(2;5)(p23;q35) in anaplastic large cell lymphoma, but not in other non- Hodgkin's lymphomas, Hodgkin's disease, or lymphomatoid papulosis
Didier A. Schmitt; Laurance Schaffar; Gerald R. Taylor; Karin C. Loftin; Victor S. Schneider; Anne Koebel; Michel Abbal; Gerald Sonnenfeld; Dorothy E. Lewis; James R. Reuben; et al.
Use of bed rest and head-down tilt to simulate spaceflight-induced immune system changes
J. Adelia McBride; Jose Rodriguez; Rajyalakshmi Luthra; Nelson G. Ordóñez; Fernando Cabanillas; William C. Pugh
T-cell-rich B large-cell lymphoma simulating lymphocyte-rich Hodgkin's disease
Bang-Ning Lee; Jian-Guo Lu; Mark W. Kline; Mary Paul; Marilyn Doyle; Claudia Kozinetz; William T. Shearer; James M. Reuben
Type 1 and type 2 cytokine profiles in children exposed to or infected with vertically transmitted human immunodeficiency virus
D.E. Lewis; A. Adu-Oppong; F.B. Hollinger; H.M. Rosenblatt; I.C. Hanson; J.M. Reuben; W. Kline m.; C.A. Kozinetz; W.T. Shearer
Sensitivity of immune complex-dissociated p24 antigen testing for early detection of human immunodeficiency virus in infants
C.A. Kozinetz; M.W. Kline; D.E. Lewis; F.B. Hollinger; J.M. Reuben; H. Rosenblatt; I.C. Hanson; H. Hammill; W.T. Shearer
Early detection of HIV in infants: Aspects of design and analysis for diagnostic test studies
R. Luthra; S. Hai; W.C. Pugh
Polymerase chain reaction detection of the t(11;14) translocation involving the bcl-1 major translocation cluster in mantle cell lymphoma
M.W. Kline; D.E. Lewis; F.B. Hollinger; J.M. Reuben; I.C. Hanson; C.A. Kozinetz; D.H. Dimitrov; H.M. Rosenblatt; W.T. Shearer
A comparative study of human immunodeficiency virus culture, polymerase chain reaction and anti-human immunodeficiency virus immunoglobulin A antibody detection in the diagnosis during early infancy of vertically acquired human immunodeficiency virus infection
J. Rodriguez; L.W.C. Pugh; Z.J.E. Romaguera; L.R. Luthra; E.B. Hagemeister; P. McLaughlin; L.L.A. Rodriguez; F. Cabanillas
Primary mediastinal large cell lymphoma is characterized by an inverted pattern of large tumoral mass and low β2 microglobulin levels in serum and frequently elevated levels of serum lactate dehydrogenase
C.F. LeMaistre; Fiona E. Craig; Carole Meneghetti; Becky McMullin; Karen Parker; James Reuben; David H. Boldt; Michae Rosenblum; Thasia Woodworth
Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers
Kathryn Lea Sewell; Karen C. Parker; Thasia G. Woodworth; James Reuben; William Swartz; David E. Trentham
DAB486IL-2 fusion toxin in refractory rheumatoid arthritis
W.C. Pugh; R. Luthra
Molecular strategies in the diagnosis of malignant lymphoma and lymphoproliferative disorders
J.E. Romaguera; W. Pugh; R. Luthra; A. Goodacre; F. Cabanillas
The clinical relevance of t(14; 18)/BCL-2 rearrangement and DEL 6q in diffuse large cell lymphoma and immunoblastic lymphoma
C.F. LeMaistre; C. Meneghetti; M. Rosenblum; J. Reuben; K. Parker; J. Shaw; A. Deisseroth; T. Woodworth; D.R. Parkinson
Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expressing the IL-2 receptor
J.M. Reuben; L. Liang; R.L. Atmar; S. Greenberg
B-cell activation and differentiation by HIV-1 antigens among volunteers vaccinated with VaxSyn HIV-1
J.M. Reuben; B. Gonik; S. Li; L. Loo; J. Turpin
Induction of cytokines in normal placental cells by the human immunodeficiency virus
Charles F. LeMaistre; Michael G. Rosenblum; James M. Reuben; David R. Parkinson; Carole M. Meneghetti; Karen Parker; Jill P. Shaw; Albert B. Deisseroth; Thasia Woodworth
Therapeutic effects of genetically engineered toxin (DAB486IL-2) in patient with chronic lymphocytic leukaemia
Francisco H. Dexeus; Christopher J. Logothetis; Avishay Sella; Karen Fitz; Robert Amato; James M. Reuben; Nicki Dozier
Phase II study of coumarin and cimetidine in patients with metastatic renal cell carcinoma
J.J. Heindel; A.S. Berkowitz; G. Kyle; R. Luthra; J.V. Bruckner
Assessment in rats of the gonadotoxic and hepatorenal toxic potential of dibromochloropropane (DBCP) in drinking water
Evan M. Hersh; J. Lee Murray; Waun Ki Hong; Michael G. Rosenblum; James M. Reuben; Robert Weilbaecher; Amar N. Sarwal; Edward C. Bradley; Michael Konrad; Frank C. Arnett
Phase I study of cancer therapy with recombinant interleukin-2 administered by intravenous bolus injection
C.C. Childs; C. Hirsch-Ginsberg; R.S. Walters; B.S. Andersson; J. Reuben; J.M. Trujillo; A. Cork; S.A. Stass; E.J. Freireich; T.F. Zipf
Myeloid surface antigen-positive acute lymphoblastic leukemia (My+ ALL): immunophenotypic, ultrastructural, cytogenic, and molecular characteristics
Gary W. Brewton; Evan M. Hersh; Adan Rios; Peter W.A. Mansell; Blaine Hollinger; James M. Reuben
A pilot study of diethyldithiocarbamate in patients with acquired immune deficiency syndrome (AIDS) and the AIDS-related complex
A. LeMaistre; C.C. Childs; C. Hirsch-Ginsberg; J. Reuben; A. Cork; J.M. Trujillo; B. Andersson; K.B. McCredie; E. Freireich; S.A. Stass
Heterogeneity in acute undifferentiated leukemia
S.P. Schantz; H.E. Savage; B.W. Brown; J.M. Reuben; W.K. Hong; R.D. Rossen
Association of levels of circulating C1q binding macromolecules with induction chemotherapy response in head and neck cancer patients
C. Hirsch-Ginsberg; C. Childs; K.-S. Chang; M. Beran; A. Cork; J. Reuben; E.J. Freireich; L.C.M. Chang; F.J. Bollum; J. Trujillo; et al.
Phenotypic and molecular heterogeneity in Philadelphia chromosome-positive acute leukemia
J.M. Reuben; M. LaRocco
Cellular immune responses in acquired immunodeficiency syndrome
A. LeMaistre; C.N. Powers; J.M. Reuben
Monoclonal antibodies and flowcytometry in characterization of acute leukemias
C.C. Childs; C. Hirsch-Ginsberg; S.J. Culbert; M. Ahearn; J. Reuben; J.M. Trujillo; A. Cork; R.R. Walters; E.J. Freireich; S.A. Stass
Lineage heterogeneity in acute leukemia with the t(4;11) abnormality: Implications for acute mixed lineage leukemia
Gabriel Lopez-Berestein; Jim Turpin; Jeane P. Hester; Charles Gschwind; James Reuben
Effects of liposomal amphotericin b on human peripheral blood monocytes and lymphocytes
E.M. Hersh; E.A. Petersen; D.E. Yocum; S.R. Gorman; M.J. Darragh; C.R. Gschwind; G.W. Brewton; J.A. Reuben
Immunological characteristics and potential approaches to immunotherapy of HIV infection.
James L. Murray; Daniel W. Bywaters; James M. Reuben; Peter W. Mansell; Evan M. Hersh
Decreased 5′nucleotidase activity in suppressor (OKT8) T lymphocytes from homosexuals with AIDS-related complex: Nonassociation with enhanced deoxynucleoside toxicity
J.L. Murray; J.M. Reuben; T.L. Smith; E.A. Gehan; S.M. Koretz; E.M. Hersh
A pilot clinical trial of the toxicity and immunorestorative effects of T cell reconstituting factor (SR 270258) in immunosuppressed cancer patients
M. Talpaz; M. Rosenblum; R. Kurzrock; J. Reuben; H. Kantarjian; J. Gutterman
Clinical and laboratory changes induced by alpha interferon in chronic lymphocytic leukemia - A pilot study
B. Drewinko; P. Moskwa; J. Reuben
Expression of transferrin receptors is unrelated to proliferative status in cultured human colon cancer cells
J.L. Lepe-Zuniga; J.R. Quesada; S. Baron; J. Reuben; J.U. Gutterman
Alpha interferon production in patients with hairy cell leukemia: Correlations with disease activity and remission status
Gabriel N. Hortobagyi; Nicholas E.J. Papadoupoulos; Debra Frye; Jaffer Ajani; James M. Reuben
Phase I clinical study of nafazatrom
J.M. Reuben; J.M. LaRocco; C.R. Gschwind; C. Stroud; A. Rios; E.M. Hersh; P.W. Mansell
Relationship of exposure to human T lymphotropic virus and T helper cells in homosexual men
Y.Z. Patt; P.W.A. Mansell; J.M. Reuben; L. Claghorn; S. Li; E. Gehan; E.M. Hersh
Effect of azimexon therapy on host defense parameters and disease-associated symptoms in the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)
J.V. Bruckner; W.F. Mackenzie; S. Muralidhara; R. Luthra; G.M. Kyle; D. Acosta
Oral toxicity of carbon tetrachioride: Acute, subacute, and subchronic studies in rats
K.C. Loftin; J.M. Reuben; W. Dalton; E.M. Hersh; D. Sujansky
Terminal transferase in leukemias by flow cytometry
Y.Z. Patt; G.M. Mavligit; J. Reuben; P.W. Mansell; G. Newell; M. Talpaz; E.M. Hersh
Modulation in vitro of immune parameters in homosexual males with the preclinical complex of symptoms related to acquired immune deficiency syndrome by azimexon
J.R. Quesada; E.M. Hersh; J. Manning; J. Reuben; M. Keating; E. Schnipper; L. Itri; J.U. Gutterman
Treatment of hairy cell leukemia with recombinant α-interferon
R. Kurzrock; J.R. Quesada; M. Talpaz; E.M. Hersh; J.M. Reuben; S.A. Sherwin; J.U. Gutterman
Phase I study of multiple dose intramuscularly administered recombinant gamma interferon
Jorge R. Quesada; James Reuben; Roy L. Hopfer; Francis K. Mundon; Evan M. Hersh
Serologic studies in hairy cell leukemia: High prevalence of Epstein-Barr and cytomegalovirus antibodies and absence of human T-cell lymphotrophic viruses antibodies
J.V. Bruckner; W.F. MacKenzie; S. Muralidhara; R. Luthra; G.M. Kyle; D. Acosta
Oral toxicity of carbon tetrachloride: Acute, subacute, and subchronic studies in rats
C.V. Sumaya; R.N. Boswell; Y. Ench; D.L. Kisner; E.M. Hersh; J.M. Reuben; P.W. Mansell
Enhanced serological and virological findings of Epstein-Barr virus in patients with AIDS and AIDS-related complex
G.N. Hortobagyi; E.M. Hersh; N.E.J. Papadopoulos; D. Frye; A. Rios; J.M. Reuben; C. Plager; M. Rosenblum; J. Quesada
Initial clinical studies with copovithane
Y.Z. Patt; E.M. Hersh; J. Reuben; L. Claghorn; G. Mavligit
A phase I study of intravenous azimexon therapy in human cancer
Guy R. Newell; Peter W.A. Mansell; Margaret R. Spitz; James M. Reuben; Evan M. Hersh
Volatile nitrites. Use and adverse effects related to the current epidemic of the acquired immune deficiency syndrome
J.L. Murray; E.M. Hersh; J.M. Reuben; C.G. Munn; P.W. Mansell
Abnormal lymphocyte response to exogenous interleukin-2 in homosexuals with acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC)
A. Rios; P.W.A. Mansell; G.R. Newell; J.M. Reuben; E.M. Hersh; J.U. Gutterman
Treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma with lymphoblastoid interferon
A.R. Zander; J.M. Reuben; D. Johnston; L. Vellekoop; K.A. Dicke; J.C. Yau; E.M. Hersh
Immune recovery following allogeneic bone marrow transplantation
J.L. Murray; K.C. Loftin; C.G. Munn; J.M. Reuben; P.W. Mansell; E.M. Hersh
Elevated adenosine deaminase and purine nucleoside phosphorylase activity in peripheral blood null lymphocytes from patients with acquired immune deficiency syndrome
A. Zander; J. Yau; J. Reuben
Early immune recovery following allogeneic bone marrow transplantation (ABMT) with T-cell depleted grafts
P. Mansell; J. Reuben; E. Hersh
The treatment of immune deficiency in patients with AIDS and AIDS related complex with copovithane (Bay i 7433)
J. Srigley; B. Barlogie; J.J. Butler; B. Osborne; M. Blick; D. Johnston; H. Kantarjian; J. Reuben; J. Batsakis; E.J. Freireich
Heterogeneity of non-Hodgkin's lymphoma probed by nucleic acid cytometry
Karin C. Loftin; James M. Reuben; Evan M. Hersh; Daniel Sujansky
Cytoplasmic IgM in leukemic B cells by flow cytometry
E.M. Hersh; J.U. Gutterman; S. Spector; H. Friedman; S.B. Greenberg; J.M. Reuben; R. LaPushin; M. Matza; P.W. Mansell
Impaired in vitro interferon, blastogenic, and natural killer cell responses to viral stimulation in acquired immune deficiency syndrome
J.L. Murray; J.M. Reuben; C.G. Munn; G. Newell; P.W.A. Mansell; E.M. Hersh
In vitro modulation of purine enzyme metabolism and lymphocyte surface marker expression by thymosin fraction 5 in homosexual males
J.M. Reuben; E.M. Hersh; J.L. Murray; C.G. Munn; S.R. Mehta; P.W. Mansell
IL-2 production and response in vitro by the leukocytes of patients with acquired immune deficiency syndrome
C. Gwyneth Munn; James M. Reuben; Evan M. Hersh; Peter W.A. Mansell; Guy R. Newell
T cell surface antigen expression on lymphocytes of patients with AIDS during in vitro mitogen stimulation
Rajyalakshmi Luthra; Glenna M. Kyle; Pramod S. Mehta; James V. Bruckner
Effects of carbon tetrachloride and 1,1-dichloroethylene on rat hepatic microsomal calcium- and/or magnesium-stimulated ATPase
K.C. Loftin; J.M. Reuben; E.M. Hersh
The measurement of cytoplasmic immunoglobulin in a B cell line and B cells from patients with chronic lymphocytic leukemia by flow cytometry
A.R. Zander; D. Johnston; J. Reuben
Does host immune status predict acute graft-versus-host-disease?
J.M. Reuben; E.M. Hersh
Delayed hypersensitivity responses of cancer patients to recall antigens using a new 'Multitest' applicator
J.L. Murray; J.M. Reuben; C.G. Munn; P.W. Mansell; G.R. Newell; E.M. Hersh
Decreased 5' nucleotidase activity in lymphocytes from asymptomatic sexually active homosexual men and patients with the acquired immune deficiency syndrome
J.R. Quesada; J. Reuben; J.T. Manning; E.M. Hersh; J.U. Gutterman
Alpha interferon for induction of remission in hairy-cell leukemia
J.V. Bruckner; R. Luthra; G.M. Kyle
Influence of time of exposure to carbon tetrachloride on toxic liver injury
E.M. Hersh; J.M. Reuben; P.W.A. Mansell
Immunologic studies of the acquired immunodeficiency syndrome: Relationship of immunodeficiency to extent of disease
C.G. Munn; J.M. Reuben; E.M. Hersh
Expression of T cell surface antigens by mitogen stimulated lymphocytes from patients with AIDS
E.M. Hersh; P.W.A. Mansell; J.M. Reuben; A. Rios; G.R. Newell
Immunological characterizations of patients with acquired immune deficiency syndrome, acquired immune deficiency syndrome-related symptom complex, and a related life-style
D.L. Jespersen; P.M. Kaplan; C. Guyneth Munn; J.M. Reuben
Determination of T helper/suppressor cell ratios in the blood of patients with acids by flow cytometry and radioimmunoassay
E.M. Hersh; J.M. Reuben; A. Rios; P.W. Mansell; G.R. Newell; J.E. McClure; A.L. Goldstein
Elevated serum thymosin alpha 1 levels associated with evidence of immune dysregulation in male homosexuals with a history of infectious diseases or Kaposi's sarcoma.
G. Lopez-Berestein; J. Reuben; E.M. Hersh; R. Kilbourn; J.P. Hester; M. Bielski; M. Talpaz; G.M. Mavligit
Comparative functional analysis of lymphocytes and monocytes from plateletapheresis
J.M. Reuben; C.E. Tanner
Protection against experimental echinococcosis by non-specifically stimulated peritoneal cells
I. Garcia; V. Fainstein; A. Rios; M. Luna; P. Mansell; J. Reuben; E. Hersh
Nonbacterial thrombotic endocarditis in a male homosexual with Kaposi's sarcoma
E.M. Hersh; P.W.A. Mansell; J.M. Reuben; J. Frank; A. Rios; R. LaPushin; G. Newell
Suppressor cell activity among the peripheral blood leukocytes of selected homosexual subjects
L.A. Guarda; J.J. Butler; P. Mansell; E.M. Hersh; J. Reuben; G.R. Newell
Lymphadenopathy in homosexual men. Morbid anatomy with clinical and immunologic correlations
J.M. Reuben; E.M. Hersh; P.W. Mansell; G. Newell; A. Rios; R. Rossen; A.L. Goldstein; J.E. McClure
Immunological characterization of homosexual males
E.M. Hersh; J.M. Reuben; H. Bogerd; M. Rosenblum; M. Bielski; P.W. Mansell; A. Rios; G.R. Newell; G. Sonnenfeld
Effect of the recreational agent isobutyl nitrite on human peripheral blood leukocytes and on in vitro interferon production
E.M. Hersh; P.W. Mansell; J.M. Reuben; A. Rios; G.R. Newell; A.L. Goldstein; K. Lynch
Leukocyte subset analysis and related immunological findings in acquired immunodeficiency disease syndrome (AIDS) and malignancies.
J.M. Reuben; E.M. Hersh; J. Lee Murray
E.M. Hersh; J.M. Reuben; P.W. Mansell; A. Rios; G.R. Newell; J. Frank; A.L. Goldstein
Immunological studies of male homosexuals with the prodrome of the acquired immunodeficiency syndrome (AIDS).
G.M. Kyle; R. Luthra; J.V. Bruckner; W.F. MacKenzie; D. Acosta
Assessment of functional, morphological, and enzymatic tests for acute nephrotoxicity induced by mercuric chloride
Jorge R. Quesada; James M. Reuben; Maria A. Scouros; Samuel G. Murphy
Autologous mixed lymphocyte reaction in lymphoid malignancies. Lack of correlation with disease activity or clinical remission
G.M. Kyle; R. Luthra; O.M. Adeyemo; J.V. Bruckner
Sensitivity and specificity of tests for chemically-induced nephrotoxicity
R. Luthra; G.M. Kyle; J.V. Bruckner
Investigation of biochemical indices of hepatotoxicity
Immunoprophylaxis with BCG of experimental Echinococcus multilocularis infections
J.M. Reuben; C.E. Tanner; V. Portelance
Protection of cotton rats against experimental Echinococcus multilocularis infections with BCG cell walls
Rajyalakshmi Luthra; Merle S. Olson
The effects of chlorotetracycline on calcium movements in isolated rat liver mitochondria
J.M. Reuben; C.E. Tanner; M.E. Rau
The inhibition of calcium uptake and release by rat liver mitochondria by ruthenium red
Studies of mitochondrial calcium movements using chlorotetracycline
M. Hillar; J. Reuben
Hormonal induction of glutamate dehydrogenase in rat liver