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Bup Feeds
Social network support for individuals receiving opiate substitution treatment and its association with treatment progress.
Social network support for individuals receiving opiate substitution treatment and its association with treatment progress.
Eur Addict Res. 2013;19(4):211-21
Authors: Day E, Copello A, Karia M, Roche J, Grewal P, George S, Haque S, Chohan G
BACKGROUND/AIMS: Social networks have been hypothesized to protect people from the harmful effects of stress, but may also provide dysfunctional role models and provide cues associated with drug use. This study describes the range, type and level of social support available to patients engaged in UK opiate substitution treatment (OST) programmes, and explores the association between network factors and continued use of illicit heroin.
METHODS: A cross-sectional survey of a randomly selected sample of OST patients (n = 118) utilised measures of current substance use and social network structure and support.
RESULTS: More than half of the participants had used heroin in the previous month, and most described networks that were both supportive and positive about treatment. Multivariate analysis showed that the substance use involvement of network members was higher in those patients still using heroin, even when other treatment factors were controlled for.
CONCLUSION: There was a strong association between ongoing contact with other drug users and continued use of illicit heroin in this treatment sample. Whilst there is potential for the involvement of social networks in treatment, future research needs to ascertain the exact nature of the relationship between social support and drug use.
PMID: 23391965 [PubMed - indexed for MEDLINE]
Increased somatic morbidity in the first year after leaving opioid maintenance treatment: results from a Norwegian cohort study.
Increased somatic morbidity in the first year after leaving opioid maintenance treatment: results from a Norwegian cohort study.
Eur Addict Res. 2013;19(4):194-201
Authors: Skeie I, Brekke M, Clausen T, Gossop M, Lindbaek M, Reinertsen E, Thoresen M, Waal H
BACKGROUND/AIMS: Some patients on opioid maintenance treatment (OMT) leave treatment temporarily or permanently. This study investigated whether patients interrupting their OMT differed from non-interrupters in sociodemographic and drug-use characteristics and examined acute/sub-acute somatic morbidity among the interrupters, prior to, during, and after OMT.
METHODS: Cohort design. OBSERVATION PERIOD: 5 years prior to, up to first 5 years during, and up to 5 years after interruption of OMT.
PARTICIPANTS: The sample (n = 200) comprised 51 OMT interrupters and 149 non-interrupters. Data on patient characteristics were obtained from interviews and OMT register information. Data on somatic morbidity were gathered from hospital records.
MEASUREMENTS: Key patient characteristics among OMT interrupters and non-interrupters. Incidence rates of acute and sub-acute somatic disease incidents leading to hospital treatment (drug-related/non-drug-related/injuries) prior to/during/after OMT.
RESULTS: Interrupters and non-interrupters did not differ in sociodemographic characteristics, while longer duration of amphetamine and benzodiazepine dependence predicted OMT interruption. Interrupters scored significantly higher on drug-taking and overdose during OMT but still had a significant 41% reduction in drug-related treatment, episodes. After interruption of treatment, such episodes increased markedly and were 3.6 times more frequent during the first post-OMT year compared to the pre-OMT period (p < 0.001). This increase was highest during the first months after OMT interruption. 2-5 years after interruption there was no significant increase.
CONCLUSIONS: Increased somatic morbidity was found among OMT interrupters during the first year after OMT, and especially during the immediate post-treatment period.
PMID: 23257574 [PubMed - indexed for MEDLINE]
Diversion of methadone and buprenorphine from opioid substitution treatment: a staff perspective.
Diversion of methadone and buprenorphine from opioid substitution treatment: a staff perspective.
J Psychoactive Drugs. 2014 Nov-Dec;46(5):427-35
Authors: Johnson B, Richert T
Abstract Opioid substitution treatment (OST) is still controversial, despite positive results. The issue of diversion to the illicit drug market is a cornerstone in the criticism typically voiced against the treatment. Little research is available concerning how professionals who work in OST view the issue of diversion. In this article, we discuss existing ideas and attitudes toward diversion of methadone and buprenorphine among OST staff in Sweden. The article is based on semi-structured interviews with 25 professionals working in eight OST-programs in southern Sweden. Diversion was seen as a deleterious phenomenon by the interviewees. Three problematic aspects were highlighted: medical risks in the form of overdose fatalities and the recruitment of new opiate/opioid users; negative consequences for the legitimacy of OST; and moral objections, since diversion means that the patients remain in a criminal environment. However, positive aspects were also highlighted. Illicit methadone or buprenorphine is perceived as safer than heroin. In this way, diversion can fulfill a positive function; for instance, if there is a shortage of access to regular treatment. Patients who share their medication with opioid-dependent friends are seen as less culpable than those who sell to anyone for money.
PMID: 25364995 [PubMed - in process]
Patient Perspectives on Buprenorphine/Naloxone: A Qualitative Study of Retention During the Starting Treatment with Agonist Replacement Therapies (START) Study.
Patient Perspectives on Buprenorphine/Naloxone: A Qualitative Study of Retention During the Starting Treatment with Agonist Replacement Therapies (START) Study.
J Psychoactive Drugs. 2014 November-December;46(5):412-426
Authors: Teruya C, Schwartz RP, Mitchell SG, Hasson AL, Thomas C, Buoncristiani SH, Hser YI, Wiest K, Cohen AJ, Glick N, Jacobs P, McLaughlin P, Ling W
Abstract This study examines the barriers and facilitators of retention among patients receiving buprenorphine/naloxone at eight community-based opioid treatment programs across the United States. Participants (n = 105) were recruited up to three and a half years after having participated in a randomized clinical trial comparing the effect of buprenorphine/naloxone and methadone on liver function. Semi-structured interviews were conducted with 67 patients provided with buprenorphine/naloxone who had terminated early and 38 patients who had completed at least 24 weeks of the trial. Qualitative data were analyzed using the constant comparison method. Barriers to buprenorphine/naloxone retention that emerged included factors associated with: (1) the design of the clinical trial; (2) negative medication or treatment experience; and (3) personal circumstances. The facilitators comprised: (1) positive experience with the medication; (2) personal determination and commitment to complete; and (3) staff encouragement and support. The themes drawn from interviews highlight the importance of considering patients' prior experience with buprenorphine/naloxone and methadone, medication preference, personal circumstances, and motivation to abstain from illicit use or misuse of opioids, as these may influence retention. Ongoing education of patients and staff regarding buprenorphine/naloxone, especially in comparison to methadone, and support from staff and peers are essential.
PMID: 25364994 [PubMed - as supplied by publisher]
Treatment Outcomes of African American Buprenorphine Patients by Parole and Probation Status.
Treatment Outcomes of African American Buprenorphine Patients by Parole and Probation Status.
J Drug Issues. 2014 Jan;44(1):69-82
Authors: Mitchell SG, Gryczynski J, Kelly SM, O'Grady KE, Jaffe JH, Olsen YK, Schwartz RP
This secondary analysis compared outcomes of African-American adults newly-admitted to buprenorphine treatment who were on parole and probation to patients who were not under criminal justice supervision. Buprenorphine patients (N=300) were randomly assigned to receive either Intensive Outpatient Treatment (IOP) or Standard Outpatient Treatment (OP) treatment and were assessed at baseline, 3- and 6-months. There were no differences between groups in treatment retention. Among probationers/parolees, IOP was associated with lower 3-month treatment retention compared to OP, but among participants not on probation/parole the relationship was reversed (p=.004). Both conditions showed significant declines in heroin and cocaine use, illegal activity, and in meeting DSM-IV criteria for opioid and cocaine dependence. Probationers/parolees reported lower frequency of illegal activities at 3-months compared to non-probationers/parolees (p=.007). Buprenorphine treatment should be made more widely available to individuals on parole/probation as they respond as well to treatment as patients not supervised by the criminal justice system.
PMID: 25364037 [PubMed - as supplied by publisher]
Striatal dopamine D1 and D2 receptors are differentially regulated following buprenorphine or methadone treatment.
Striatal dopamine D1 and D2 receptors are differentially regulated following buprenorphine or methadone treatment.
Psychopharmacology (Berl). 2014 Oct 31;
Authors: Allouche S, Le Marec T, Coquerel A, Noble F, Marie N
RATIONALE: Chronic administration of morphine induces adaptations in neurotransmission system such as the dopamine pathway, and these modifications could be influenced by the drug administration pattern. Methadone and buprenorphine are the two main opioid substitution therapies, and despite their protracted use in humans, no study has investigated their ability to regulate dopamine system after chronic exposure/withdrawal.
OBJECTIVES: We evaluated the consequences of two administration patterns of methadone and buprenorphine on striatal dopamine D1 (D1R) and D2 (D2R) receptor levels.
METHODS: Mice were treated with escalating doses of methadone or buprenorphine for 5 days either once daily (binge) or three times a day (TTD). D1R and D2R density in striatum was measured by autoradiography using [(3)H]-SCH23390 and [(3)H]-raclopride, respectively, at 1 (WD1), 14 (WD14), and 35 (WD35) days after the last opioid injection.
RESULTS: A downregulation of D1R was observed upon TTD administration of buprenorphine and binge methadone treatment while an increase of those receptor levels was detected both with binge buprenorphine and TTD methadone treatments. Concerning the D2R, we rather measured an early or late downregulation with both agonists and administration patterns.
CONCLUSIONS: Our results demonstrated that methadone and buprenorphine were able to differentially regulate dopamine receptor density depending on the withdrawal period and the administration pattern.
PMID: 25358852 [PubMed - as supplied by publisher]
23-year-old woman being treated for opioid dependence, unexpected weight gain.
23-year-old woman being treated for opioid dependence, unexpected weight gain.
J Fam Pract. 2014 Jul;63(7):366-7
Authors: Chudgar NP, Greenblatt L
PMID: 25198209 [PubMed - indexed for MEDLINE]
Prescribing of drugs for attention-deficit hyperactivity disorder in opioid maintenance treatment patients in Norway.
Prescribing of drugs for attention-deficit hyperactivity disorder in opioid maintenance treatment patients in Norway.
Eur Addict Res. 2014;20(2):59-65
Authors: Karlstad Ø, Furu K, Skurtveit S, Selmer R
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is a risk factor for the development of substance use disorders. Treatment of ADHD with psychostimulants in patients on opioid maintenance treatment (OMT) has been restricted in Norway. We examined the use of prescribed drugs for ADHD in OMT patients and assessed co-medication with other psychotropics.
METHODS: Data were drawn from the nationwide Norwegian Prescription Database (NorPD), which includes all prescriptions filled at pharmacies. The study population included subjects ≥18 years on OMT during 2008-2010.
RESULTS: In 2010, 6,116 patients received OMT and 2.8% of these also received ADHD drugs. This percentage is seven times greater than that in the gender- and age-specific general population of Norway. The prevalence was higher in the youngest patients, while there was no gender difference. Methylphenidate was the most commonly used drug for ADHD in OMT patients, followed by atomoxetine. 60% of OMT patients filled at least one prescription for antidepressants, anxiolytics or hypnotics, and percentages were similar for users and non-users of ADHD drugs.
CONCLUSION: Treatment with ADHD drugs was higher in OMT patients than expected from the general population, but was relatively low compared to the prevalence of ADHD in patients with substance use disorders reported in the literature.
PMID: 24080771 [PubMed - indexed for MEDLINE]
Methadone versus morphine for treatment of neonatal abstinence syndrome: A prospective randomized clinical trial.
Methadone versus morphine for treatment of neonatal abstinence syndrome: A prospective randomized clinical trial.
J Perinatol. 2014 Oct 30;
Authors: Brown MS, Hayes MJ, Thornton LM
Objective:Compare duration of treatment of neonatal abstinence syndrome between methadone and morphine.Study design:A prospective, double-masked, randomized trial at a single site. Randomization of methadone or morphine was stratified for maternal treatment with methadone or buprenorphine. Inclusion criteria were (i) maternal treatment with prescribed methadone or buprenorphine, (ii) withdrawal treatment criteria, (iii) adjusted gestational age ⩾35(0/7) weeks and (iv) medically stable. Primary outcome was length of opioid treatment.Result:From January 2011 through October 2012, 78 infants were eligible for the study: 41 methadone-exposed and 37 buprenorphine-exposed. Consent was obtained from 31 mothers, 13/41 (32%) methadone-treated and 18/37 (49%) buprenorphine-treated. Length of opioid treatment was significantly shorter for methadone than morphine treatment, median 14 versus 21 days (P=0.008).Conclusion:Methadone had a shorter length of neonatal withdrawal treatment compared with morphine. Owing to the smaller sample size and single site, a larger randomized study is needed.Journal of Perinatology advance online publication, 30 October 2014; doi:10.1038/jp.2014.194.
PMID: 25357093 [PubMed - as supplied by publisher]
Executive function in preschool children prenatally exposed to methadone or buprenorphine.
Executive function in preschool children prenatally exposed to methadone or buprenorphine.
Child Neuropsychol. 2014 Oct 30;:1-16
Authors: Konijnenberg C, Melinder A
Although an increasing number of children are born with prenatal methadone or buprenorphine exposure, little is still known about the potential long-term effects of these opioids. The aim of this study was to investigate executive function (EF) in children of women in opioid maintenance therapy (OMT). A total of 66 children (aged 48-57 months) participated in the study, 35 of which had histories of prenatal methadone or buprenorphine exposure. EF was measured using a battery of neuropsychological tests and the Behavior Rating Inventory of Executive Function-Preschool Version (BRIEF-P). Results showed that children of women in OMT perform lower on tasks of short-term memory and inhibition compared to nonexposed children, which was mainly associated with lower maternal education and employment rate. The OMT group scored significantly lower on all EF tasks compared to the nonexposed group, although scores fell within the average range on all measures. The development of these children should be monitored to assess for the possible problem behaviors and to promote optimal outcomes.
PMID: 25354916 [PubMed - as supplied by publisher]
Somatosensory and auditory processing in opioid-exposed newborns with neonatal abstinence syndrome: a magnetoencephalographic approach.
Somatosensory and auditory processing in opioid-exposed newborns with neonatal abstinence syndrome: a magnetoencephalographic approach.
J Matern Fetal Neonatal Med. 2014 Oct 29;:1-17
Authors: Kivistö K, Nevalainen P, Lauronen L, Tupola S, Pihko E, Kivitie-Kallio S
Abstract Objective: Opioid exposure during pregnancy is a potential risk factor for the developing central nervous system of the fetus. We studied evoked responses in buprenorphine-exposed newborns who displayed neonatal abstinence syndrome (NAS) to elucidate the possible alterations in functioning of the somatosensory and auditory systems. Methods: We compared somatosensory (SEFs) and auditory evoked magnetic fields (AEFs), recorded with magnetoencephalography (MEG), of 11 prenatally buprenorphine-exposed newborns with those of 12 healthy newborns. Peak latencies, source strength, and location of SEFs or AEFs were recorded. Results: AEFs were present in all buprenorphine-exposed newborns without significant differences from those of healthy newborns. In contrast, though no group level differences in SEFs existed, at individual level the response deviated from the typical neonatal morphology in four buprenorphine-exposed newborns. Conclusions: Although buprenorphine exposure during pregnancy does not seem to cause constant deficiencies in somatosensory or auditory processing, in some newborns the typical development of somatosensory networks may be - at least transiently - disrupted.
PMID: 25354289 [PubMed - as supplied by publisher]
Livedo-like dermatitis and necrotic lesions after high-dose buprenorphine injections: a national French survey.
Livedo-like dermatitis and necrotic lesions after high-dose buprenorphine injections: a national French survey.
Br J Dermatol. 2014 Oct 29;
Authors: Wainstein L, Bernier C, Gérardin M, Bouquié R, Espitia O, Mussini JM, Jolliet P, Victorri-Vigneau C
Buprenorphine is a partial opioid agonist used as an oral maintenance treatment for opioid dependence, under the form of high-dose. The branded form of high-dose buprenorphine (HDB) -Subutex(®) - was introduced in France in 1996. Several generic drugs have been marketed ten years later. HDB has become the first oral maintenance treatment for opioid dependence in France. This article is protected by copyright. All rights reserved.
PMID: 25353069 [PubMed - as supplied by publisher]
Clinical Benchmarks Regarding Multimodal Peripheral Nerve Blocks for Postoperative Analgesia: Observations Regarding Combined Perineural Midazolam-Clonidine-Buprenorphine-Dexamethasone.
Clinical Benchmarks Regarding Multimodal Peripheral Nerve Blocks for Postoperative Analgesia: Observations Regarding Combined Perineural Midazolam-Clonidine-Buprenorphine-Dexamethasone.
Pain Med. 2014 Oct 28;
Authors: Williams BA, Ibinson JW, Mangione MP, Scanlan RL, Cohen PZ
PMID: 25351887 [PubMed - as supplied by publisher]
Trick and Treat: 5 Ways to Reduce Teen Mischief this Halloween
Its a fact: teens trick their parents from time to time. Experts say its normal for teens to stretch rules, take risks and try out some trickery (just think back to when you were a teen.) But there are some key things parents can do to keep their teens safe and healthy. With Halloween this weekend, why not roll up your sleeves and do some productive tricking and treating of your own?
Here are 5 ways parents can reduce teen mischief and encourage a healthy relationship with their teen on Halloween and beyond.
- Trick Them Into Talking
* Listen First: Let teens vent, talk and not feel judged and be sure to keep the focus on them when they are talking to you.
* Ask The Right Questions: Instead of giving advice, ask questions. Ask them more about how they feel, what they think they should do, what others have done. Not only will you learn more about how your teen thinks, you will also help them explore their own situation.
* Let them, or show them, how to come to their own answers: When you ask them questions, try to guide them to come up with the answer on their own, instead of you telling them what to do. That way, they will feel more empowered.
2. Treat Your Family to a Screen-Free Evening
Turn off all smartphones, gaming devices, iPads, TVs, etc. and give one another your undivided attention. Make eye-contact, ask questions and share stories. As hard as it might be — don't jump to respond to every ping or text on your phone. Show your teen that you're curious about her world and that what she has to say is more important than any screen. (And make sure she does the same.)
3. Trick Your Teens Into Staying Out of Trouble
Encourage your teen to do something out of her wheelhouse. Perhaps he joins a new club at school, tries a new sport or does some community service. This will give her something structured to do after school, and she can include her wider circle of friends in the activities — and, it's always worthwhile to try new things, even if he's not good at it. Ask other parents in your community or at your place of worship for how your teen can get actively involved in community volunteering.
4. Trick Them Into Feeling Good About Themselves
Give your teen lots of praise and positive feedback. Teens need to hear the "good stuff" just like the rest of us. They need to know you can still see beyond the things they do wrong from time to time. Catch them being good and always reward positive, responsible, mature behavior to help build their own self-esteem so they make more positive choices.
5. Treat Them with Love and Support
It's important that teens feel supported by their parents, so be sure to let your child know that he or she can always count on you and come to you for guidance when she's stressed or dealing with a personal issue. Remind your teen that the reason you're always talking with her and asking questions is because you love her, care about her and want her to be healthy and successful.
Have a safe, happy and healthy Halloween!
The post Trick and Treat: 5 Ways to Reduce Teen Mischief this Halloween appeared first on Partnership for Drug-Free Kids.
An Unusual Case of Death Probably Triggered by the Association of Buprenorphine at Therapeutic Dose with Ethanol and Benzodiazepines and with Very Low Norbuprenorphine Level.
An Unusual Case of Death Probably Triggered by the Association of Buprenorphine at Therapeutic Dose with Ethanol and Benzodiazepines and with Very Low Norbuprenorphine Level.
J Forensic Sci. 2014 Oct 27;
Authors: Bardy G, Cathala P, Eiden C, Baccino E, Petit P, Mathieu O
Buprenorphine is largely prescribed for maintenance treatment in opioid dependence due to its safety profile. Nevertheless, fatalities at therapeutic dose have been described when associated with other central nervous system depressants, such as ethanol or benzodiazepines. Here, we report a case of death due to association of buprenorphine at therapeutic dose with benzodiazepines and ethanol. Although toxicity has been often attributed to its metabolite norbuprenorphine rather than to buprenorphine itself, in our case, norbuprenorphine was not detected in urine and bile and only in traces in blood. Moreover, the presence in blood of free buprenorphine but not of glucuronide metabolites argues for an unusual early death, at the beginning of buprenorphine metabolism. We propose that in the context of prior toxic impregnation, buprenorphine directly (and not via its metabolite norbuprenorphine) acted as a triggering factor by blocking the ventilatory response, rapidly leading to fatal respiratory depression.
PMID: 25348172 [PubMed - as supplied by publisher]
Association of Opioid Agonist Therapy With Lower Incidence of Hepatitis C Virus Infection in Young Adult Injection Drug Users.
Association of Opioid Agonist Therapy With Lower Incidence of Hepatitis C Virus Infection in Young Adult Injection Drug Users.
JAMA Intern Med. 2014 Oct 27;
Authors: Tsui JI, Evans JL, Lum PJ, Hahn JA, Page K
Importance: Injection drug use is the primary mode of transmission for hepatitis C virus (HCV) infection. Prior studies suggest opioid agonist therapy may reduce the incidence of HCV infection among injection drug users; however, little is known about the effects of this therapy in younger users.
Objective: To evaluate whether opioid agonist therapy was associated with a lower incidence of HCV infection in a cohort of young adult injection drug users.
Design, Setting, and Participants: Observational cohort study conducted from January 3, 2000, through August 21, 2013, with quarterly interviews and blood sampling. We recruited young adult (younger than 30 years) injection drug users who were negative for anti-HCV antibody and/or HCV RNA.
Exposures: Substance use treatment within the past 3 months, including non-opioid agonist forms of treatment, opioid agonist (methadone hydrochloride or buprenorphine hydrochloride) detoxification or maintenance therapy, or no treatment.
Main Outcomes and Measures: Incident HCV infection documented with a new positive result for HCV RNA and/or HCV antibodies. Cumulative incidence rates (95% CI) of HCV infection were calculated assuming a Poisson distribution. Cox proportional hazards regression models were fit adjusting for age, sex, race, years of injection drug use, homelessness, and incarceration.
Results: Baseline characteristics of the sample (n = 552) included median age of 23 (interquartile range, 20-26) years; 31.9% female; 73.1% white; 39.7% who did not graduate from high school; and 69.2% who were homeless. During the observation period of 680 person-years, 171 incident cases of HCV infection occurred (incidence rate, 25.1 [95% CI, 21.6-29.2] per 100 person-years). The rate ratio was significantly lower for participants who reported recent maintenance opioid agonist therapy (0.31 [95% CI, 0.14-0.65]; P = .001) but not for those who reported recent non-opioid agonist forms of treatment (0.63 [95% CI, 0.37-1.08]; P = .09) or opioid agonist detoxification (1.45 [95% CI, 0.80-2.69]; P = .23). After adjustment for other covariates, maintenance opioid agonist therapy was associated with lower relative hazards for acquiring HCV infection over time (adjusted hazard ratio, 0.39 [95% CI, 0.18-0.87]; P = .02).
Conclusions and Relevance: In this cohort of young adult injection drug users, recent maintenance opioid agonist therapy was associated with a lower incidence of HCV infection. Maintenance treatment with methadone or buprenorphine for opioid use disorders may be an important strategy to prevent the spread of HCV infection among young injection drug users.
PMID: 25347412 [PubMed - as supplied by publisher]
[Pharmacotherapy of heroin addiction.]
[Pharmacotherapy of heroin addiction.]
Neuropsychopharmacol Hung. 2014 Sep;16(3):127-140
Authors: Hosztafi S, Furst Z
Heroin addiction is one of the most devastating and expensive of public health problems. The most effective treatment for this epidemic is opioid replacement therapy. Replacement of heroin, a short-acting euphoriant with methadone or other opioids that have significantly longer durations of action provides a number of therapeutic benefits. Opioid detoxification has a role in both preventing acute withdrawal and maintaining long-term abstinence. Opioid-based detoxification is based on the principle of cross-tolerance, in which one opioid is replaced which another that is slowly tapered. For the treatment of heroin addicts a wide range of psychosocial and pharmacotherapeutic treatments is available; of these, methadone maintenance treatment has the most evidence of benefit. Methadone maintenance reduces and/or eliminates the use of heroin, reduces the death rates and criminality associated with heroin use, and allows patients to improve their health and social productivity. In addition, enrollment in methadone maintenance has the potential to reduce the transmission of infectious diseases associated with heroin injection, such as hepatitis and HIV. The principal effects of methadone maintenance are to relieve narcotic craving, suppress the abstinence syndrome, and block the euphoric effects associated with heroin. There is growing interest in expanding treatment into primary care, allowing opioid addiction to be managed like other chronic illnesses. Buprenorphine which is a long-acting partial agonist was also approved as pharmacotherapy for opioid dependence. Opioid antagonists can reduce heroin self-administration and opioid craving in detoxified addicts. Naltrexone, which is a long-acting competitive antagonist at the opioid receptors, blocks the subjective and objective responses produced by intravenous opioids. Naltrexone is employed to accelerate opioid detoxification by displacing heroin and as a maintenance agent for detoxified formerly heroin-dependent patients who want to remain opioid-free.
PMID: 25347242 [PubMed - as supplied by publisher]


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subset: commoncrawl


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Make Sure Brianne Is Not Alone This Holiday Season
Your contributions to Brianne's journal this year made sure that they never felt alone. Your tax-deductible donation in Brianne's honor will make sure that Caringbridge continues to bring hope and healing to those who need it most.
By Tiffany Rust Oct 3, 2013 3:16pm
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Running in the Media: From Movies to Fashion Shows
posted 9/11/2014
When they're not swanning with actors and models, these bloggers also have advice for half marathoners and new runners. more
posted 9/11/2014
When they're not swanning with actors and models, these bloggers also have advice for half marathoners and new runners. more
posted 9/9/2014
Many running and biking paths and trails are run by parks departments of their respective cities and are closed at night. Should they be opened for runners and bikers to use 24/7? more
posted 9/6/2014
American records in distance events don't happen often. It's not easy to run faster than any American has ever run at any distance. But U.S. elite athletes are on an upswing, with an impressive group who could potentially rewrite the record books in many events. more
posted 9/4/2014
Many runners have only two speeds, easy and hard. Once a runner starts racing a variety of differences, it quickly becomes clear that it helps to have a variety of gears. You can train to instinctively know what your pace is, even without the help of a GPS. more
posted 8/30/2014
Mizuno launched an ad campaign in March with 16 second spots on how the world would be different if everyone ran. They employed a group of MBA students from a University of North Carolina business school to generate statistics based on potential benefits of 270 million sedentary Americans were to start running at least 30 minutes a week. more
posted 8/28/2014
Also read about running helps with a runner's mental health, and most importantly, a photo gallery of runners and their dogs! more
posted 8/23/2014
After over a month-long break, the IAAF Diamond League series resumed on Thursday at the DN Galan meet in Stockholm, Sweden. The biggest news is Jenny Simpson's dramatic victory in the 1500. more
posted 8/21/2014
About 8 to 15% of all runners have dealt with Achilles injuries. The fad of Vibram Five Fingers shoes (those shoes that make you look like you have cartoon feet) and other low-profile thin-soled shoes may have increased those numbers. more
posted 8/19/2014
Bob Glover, author of the bestselling "The Competitive Runner's Handbook," (which I bought when I first started running) recently wrote about when he was Athletic Director at New York's West Side YMCA in 1975, he recruited Robin Williams onto his YMCA team. For a short time they trained together and raced together. Then Williams disappeared to become a comedian/actor superstar. more
posted 8/16/2014
Vegetarianism may not be for everyone, but there's no rule that says you have to be 100% in or out. If everyone picked at least one day a week to skip meat in their diet, there would be enormous benefits in both health and the environment. more
Copyright © 2014 YMCA of the USA. All rights reserved.
The YMCA is a nonprofit organization whose mission is to put Christian principles into practice through programs that build healthy spirit, mind and body for all.


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Save to My Recipes
Sorghum Spice Cake
Published: February 2012 Servings: 10–12
- 1 cup plus 2 tablespoons (2 1/4 sticks) unsalted butter, room temperature, divided, plus more for pan
- 2 cups plus 1/4 cup all-purpose flour, divided, plus more for pan
- 1 1/4 cups sugar, divided
- 1 teaspoon baking soda
- 1 teaspoon ground cinnamon
- 3/4 teaspoon kosher salt
- 1/2 teaspoon ground allspice
- 1/2 teaspoon ground ginger
- 1/4 teaspoon ground nutmeg
- 1/2 cup sorghum syrup
- 2 large eggs
- 1 cup buttermilk
- Rum raisin ice cream
Nutritional Information
12 servings, 1 serving contains (analysis does not include ice cream):
- Calories (kcal) 369.2
- %Calories from Fat 42.9
- Fat (g) 17.6
- Saturated Fat (g) 10.9
- Cholesterol (mg) 76.9
- Carbohydrates (g) 49.3
- Dietary Fiber (g) 0.5
- Total Sugars (g) 33.3
- Net Carbs (g) 48.8
- Protein (g) 4.0
- Sodium (mg) 186.7
PREPARATIONView Step-by-Step Directions
Preheat oven to 325°. Butter and flour springform pan. Combine 1/4 cup flour, 1/4 cup sugar, and 2 Tbsp. butter in a small bowl. Using your fingertips, rub together until mixture is crumbly; set topping aside. Sift remaining 2 cups flour, baking soda, and next 5 ingredients into a large bowl. Using an electric mixer at low speed, beat 1 cup butter, 1 cup sugar, and sorghum in another large bowl, occasionally scraping down sides, until smooth, 2–3 minutes. Add eggs; beat until light and fluffy, 3–4 minutes. Beat in flour mixture in 3 additions, alternating with buttermilk in 2 additions, beginning and ending with dry ingredients. Pour batter into prepared pan.
Bake cake until top looks just set, about 40 minutes.
Immediately sprinkle topping over cake; bake until a tester comes out clean when inserted into center, 25–30 minutes longer. Transfer to a wire rack and let cake cool in pan. Remove pan sides.
Cut into wedges; serve with ice cream.
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I agree. I thought this was
I agree. I thought this was the Daily Paul, not the Daily Jones. I'm going to stop visiting here if I see anymore posts that just drive new supporters away thinking 'wow, so all the Ron Paul supporters are just conspiracy theorists' I guess what the MSM says is right. Anyone reading this... we are not all truthers!
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In-flight distractions: Something's bugging me
Bedbugs on British Airways flights9
British Airways: London Airways?
British Airways is neglecting the regions24
Budget airlines: In the cheap seats
With traffic expected to slow, low-cost air carriers are getting fancy2
British Airways: A new start, and an old problem, for BA
The merger of BA and Iberia begins officially, but the threat of cabin-crew strikes takes the gloss off the day4
Rising APD: Going ape about APD
The imminent rise in APD finds few fans inside the aviation industry13
Ryanair joke: British Airways' joke offering
BA's chairman makes a joke4
Aviation security: Where the Americans get it wrong
The chairman of BA criticises the security procedures required by America24
BA's big plans: What BA does next
Expansion plans of the International Airlines Group4
BA's big mistake: "We're about to crash"
Not so much23
British Airways' seating policy: Mirko Fischer wins again
After losing a lawsuit, the airline changes its policies7
AA, BA and Iberia: Green light for BA, AA and Iberia
The European Commission approves a trans-Atlantic joint venture2
British Airways: In praise of BA
One British flyer admires the airline's quiet calm48
British Airways' seating policy: Aagh! A man!
Let's all laugh at BA's sexist seating policy20
British Airways' embarrassment: Bin Laden's boarding pass
British Airways and the embarrassing magazine cover10
British Airways loses out at the court of appeal1
British Airways: Sackcloth and ashes
An entrenched dispute takes the shine off a proud airline15
BA's lawyers win another victory5
British Airways strikes: Looming strife
Is British Airways trying to break its unions?6
The effect on business and leisure: Volcanic fallout
The ban on flights caused anger among airlines and chaos for travellers5
Volcano reactions: The volcanic blame game
British Airways finds someone to blame for the current aviation chaos11
FIFA and corruption: Hear no evil
Game theory
Illegal immigration: Those huddled masses
Democracy in America
The Economist/FT survey: Global business barometer
Graphic detail
Ukraine's economy: It is really that bad
Free exchange
Conundrums: A glut-wrenching experience
Free exchange
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Can I convert my Flash sites to HTML5?
Due to the fact that the Flash and HTML5 Editors work on different technology, it is not possible to convert from one to the other.
We do have a wide range of HTML5 templates for you to choose from. To find a template, use the search bar at the top or browse through the categories on the left.
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11-20 of 27 properties for sale found
4 bedroom terraced house for sale Brigwood, Haydon Bridge, NE47
THIS VERY WELL PRESENTED, SUBSTANTIAL four bedroomed, two reception rooms, character property is located in the heart of Haydon Bridge. Viewing is absolutely essential to appreciate this deceptively spacious family home. Benefitting from oil central heating and double glazing the accommodation br More details ›
Land for sale Land At John Martin Street, Haydon Bridge, Hexham, NE47
The former Anchor Garage occupies the site which extends to approximately 0.19 acres. The industrial buildings used by the garage still remain on site. The site sits between residential terraces on the road front and the current buildings sits slightly back from the road.... More details ›
£195,000 Guide Price
Guide Price £195,000
Land for sale TYNE VALLEY, Haydon Bridge
Development opportunity with planning consent for the construction of a detached dwellingThe property represents a unique opportunity to purchase a building plot with stunning south facing views over the Tyne Valley, situated in the popular location of North Bank, Haydon Bridge. More details ›
Added on 18/12/2013 by Foster Maddison Property Consultants, Hexham. Call: 01434 410025 Local call rate
£179,950 Offers in Region of
Offers in Region of £179,950
4 bedroom terraced house for sale Ratcliffe Road, Haydon Bridge
VENDORS COMMENTS: We bought this 4 bedroomed home for the unusually large size of the rooms , and the versatility of the living space , we also wanted a low maintenance outdoor area which was private and quiet . We required a master bedroom with ensuite as we often have guests and this ticked al... More details ›
Added on 03/04/2014 by Andrew Coulson Property Sales & Lettings, Hexham. Call: 01434 410020 Local call rate
£179,950 Offers in Excess of
- Photos: 8
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Offers in Excess of £179,950
Commercial property for sale Little Badgers Child Care, Childrens Day Nursery, Haydon Bridge
Little Badgers Child Care, Childrens Day Nursery, Haydon Bridge, NE47 6BN. Registered for 42 Children. Turnover Circa £130,000 per annum. Building Owned Outright. Located on Land on a Long Leasehold Basis (49 Years). School Next Door Used for Older Children. Ground Rent £680 per annum. More details ›
Marketed by Rook Matthews Sayer, Newcastle Upon Tyne - Commercial Properties. Call: 0191 212 0000 Local call rate
£179,000 Offers in Region of
Offers in Region of £179,000
4 bedroom terraced house for sale Ratcliffe Road, Haydon Bridge,
A substantial and highly deceptive four bedroom character property (formerly the village Post Office) situated in a central Haydon Bridge location. The property would benefit from cosmetic updating and offers rooms to include: More details ›
Reduced on 10/10/2014 by Red Hot Property, Hexham. Call: 01434 410022 Local call rate
3 bedroom terraced house for sale Innerhaugh Mews, Haydon Bridge, Hexham
Situated in the popular Tyne Valley village of Haydon bridge which has excellent road and rail links to Newcastle and Carlisle, this three bedroom family home benefits from LPG central heating and double glazing, modern fitted kitchen/breakfast room and bathroom, parking and an integral garage,... More details ›
£139,950 Offers Over
Offers Over £139,950
3 bedroom terraced house for sale Shaftoe Street, Haydon Bridge, NE47
This delightful three bedroomed terrace has been renovated over recent years and is beautifully presented whilst retaining character features. Benefitting from electric central heating and double glazing the accommodation briefly comprises: Entrance Hall, Lounge, Breakfasting Kitchen, Master Bedr More details ›
2 bedroom cottage for sale Haydon Bridge, Hexham
Tucked away in a pleasant location within the village of Haydon Bridge, this two bedroom stone built terraced cottage benefits from having double glazing and oil central heating. This well presented cottage would suit a number of buyers, those looking for their first home, retirement or holiday... More details ›
£125,000 Guide Price
Guide Price £125,000
2 bedroom end of terrace house for sale Haydon Bridge
Tucked away on the banks of the River Tyne, this well presented two bedroom home offers a picturesque view over the river and the surrounding area. Adjacent to the pedestrian bridge, on Shaftoe Street this is an ideal first purchase or holiday home, viewing comes recommended. More details ›
Reduced on 15/11/2014 by Youngs RPS LLP, Hexham. Call: 01434 410028 Local call rate
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prepressSyllabification: pre·press
Pronunciation: /ˌprēˈpres /
Definition of prepress in English:
Of or relating to typesetting, page layout, and other work done on a publication before it is actually printed.
Example sentences
- Writing, editing, layout and pre-press preparations are computerised and the publishing workflow is all network based.
- The digital graphics department is essentially the company's pre-press operation - turning working files into a set of electronic masters, with exact specifications for color and alignment on printing presses.
- Those affected were people working in pre-press, clerical and 'facilities and services' areas.
Definition of prepress in:
- British & World English dictionary
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Word of the day ingratiate
Pronunciation: inˈɡrāSHēˌāt
bring oneself into favor with someone through flattery…


text:
For new questions please post at magento.stackexchange.com, the community-run support site for the Magento community. We will be providing updates on the new forum solution soon. For questions or concerns please email email@example.com.
Apologies for the cross posting here from http://www.magentocommerce.com/boards/viewthread/23325/P15/#t214481 but it just dawned on me that this is actually most likely version related.
I installed a new clean install of Magento Version 22.214.171.124 and the sample data and added in the Google Analytics tracking code in the System -> Configuration - Google API -> Google Analytics Account Number.
Upon completion of an order the success page (index.php/checkout/onepage/success/) does successfully show the Google Analytics page view tracking but does *not* show the ecommerce transaction tracking.
Looking into this a little bit further I looked at Ga.php (/app/code/core/Mage/GoogleAnalytics/Block) where the Analytics code gets written. It does (of course) have the full code to add the transactions for ecommerce tracking but they arenât getting added to the return call for some reason. It appears (from what I can tell) that $this->getQuote(); in the getQuoteOrdersHtml() function is returning null.
As I say this is a totally new clean simple install and from everything I have read the ecommerce tracking is getting added automatically for many of you (however not for others I suspect).
Any thoughts, suggestions and/or ideas (or even verification that the same is happening for others) would be appreciated.
Note I did see an article which was relating to the JS and Analytics not returning correctly but I don't think this is pertinent as it isn't even getting as far as inserting it onto the page. http://www.magentocommerce.com/boards/viewthread/77774/
Just FYI on this, I have updated now to 184.108.40.206 however the issue is still happening (no ecommerce tracking entries being added to the page).
Funny phenomenon. - got the same issue. Surprising though - having two virtually identical installations in respect of theme/template of 184.108.40.206 on one Analytics works fine (the one i upgraded from 22.214.171.124). The other one - a freshly installed 22.214.171.124 Analytics doesn't work.
Also tried upgrading to 126.96.36.199 has no positive effect on this issue.
Seems an upgrade from 184.108.40.206 to 1.4x Google Analytics works. But not on freshly installed 1.4?
See http://www.magentocommerce.com/boards/viewthread/23325/P15/
There are two fixes mentioned here *both* of which need to be applied.
1 - Move the analytics tracking code to before the body.
2 - Add the missing declaration for the _gaq variable to Ga.php.
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21st February 2013
American football star Tim Tebow backs out of speech at anti-gay Dallas church 16
6:50 PM — New York Jets quarterback Tim Tebow has cancelled a speech he was due to make at a controversial anti-gay church in Dallas.
18th February 2013
US: NFL Footballer Tim Tebow to speak at anti-gay Dallas megachurch 15
4:09 PM — An American football player for the New York Jets best known for during-game prayers, has been invited to speak at a church in Dallas, the leader of which has been criticised for denouncing homosexuality in the past.
17th February 2013
Gay rights group: 'Sports in the US have reached a tipping point against homophobia' 5
8:37 PM — The decision of 25-year-old former Leeds United football player Robbie Rogers, to come out last week, has been commended by gay rights activists, who have described this as a "tipping point" for sports.
12th February 2013
US: Basketball player Kobe Bryant chastises Twitter fan for using 'gay' as an insult 8
1:55 AM — A US basketball player has been commended for voicing his disapproval at a fan's use of the word "gay" as an insult.
2nd February 2013
NFL player Chris Culliver to undergo sensitivity training for homophobic comments 14
7:19 PM — San Francisco 49ers player, Chris Culliver, who earlier this week said there were no gay players on the team, and if there were, they wouldn't be welcome, is to begin sensitivity training following this weekend's Super Bowl.
1st February 2013
Brendon Ayanbadejo: 50% of NFL players share Chris Culliver's homophobic views 4
7:05 PM — Ravens player Brendon Ayanbadejo has estimated that 50% of NFL players have homophobic views.
Brendon Ayanbadejo: I hope Chris Culliver's anti-gay NFL comments start a positive discussion 2
1:13 AM — American football player and equal marriage advocate, Brendon Ayanbadejo, has said that he hopes to start a positive dialogue about gay players in the NFL following anti-gay comments by fellow player, Chris Culliver.
31st January 2013
NFL player Chris Culliver apologises for saying gay players not welcome in the NFL 13
1:33 PM — Chris Culliver, an NFL player who said that there were no gay people on his team, and that if there were any, they should leave, has apologised, and said his comments were "hurtful and ugly".
30th January 2013
NFL Player Chris Culliver: Gay players aren't welcome in football and shouldn't come out 50
10:39 PM — NFL Player, Chris Culliver, has said in an interview that he didn't think there were any gay players on his team, and that they wouldn't be welcome if there were.
US: Gay former American football player charged with assaulting ex-boyfriend
4:47 PM — A retired American football player has been charged with felony domestic violence and assault charges involving a former boyfriend.
US: Leading sports magazine features gay kiss in Super Bowl preview 6
3:19 PM — The leading sports magazine in America has featured a gay celebratory kiss in a feature around the upcoming Super Bowl.
25th January 2013
Brendon Ayanbadejo: I want to use Super Bowl media for equal marriage awareness 7
5:30 PM — NFL player, and equal marriage advocate, Brendon Ayanbadejo, has said that he wants to use the massive exposure which the Super Bowl brings to speak out about marriage equality.
18th January 2013
US: Pro-gay NFL player Chris Kluwe to release a book of 'uncensored personal essays' 5
5:30 PM — Equal rights advocate and NFL football player, Chris Kluwe, is to release a book containing "uncensored personal essays" on a range of topics, after passionately defending equal marriage rights for gay people.
17th January 2013
US: NFL player Chris Kluwe to receive award for his support of gay rights and equal marriage 3
1:04 PM — Pro-gay NFL player, Chris Kluwe, is to be honoured by an LGBT community group, for being an advocate of equal rights and equal marriage for the LGBT community.
11th January 2013
Gay former NFL player says there are many 'semi-openly' gay US athletes 6
3:57 AM — An openly-gay former National Football League (NFL) player has said that he thinks there is at least one gay "significant contributor" in the NFL.
27th November 2012
NFL player: "Saying faggot doesn't make me a homophobe, it's just a word" 72
6:19 PM — An American football player in Ohio has apologised after using the word "faggot" on Twitter.
14th November 2012
Brendon Ayanbadejo thanked by rival NFL players for his support of equal marriage
1:01 AM — NFL player, Brendon Ayanbadejo, said he was congratulated by members of a rival team, during a match on Sunday, for his advocacy of equal rights, in particular his efforts in the recent battle over equal marriage.
5th November 2012
US: Chris Kluwe quits blog because of anti-equal marriage editorial 7
11:44 PM — NFL player, Chris Kluwe, has quit his blog at an online daily newspaper, due to an editorial published by the site's editors which, he said, expresses an anti-equal marriage stance which goes against the political neutrality it claims to have.
24th October 2012
Chris Kluwe: First openly gay NFL player will have 'biggest marketing opportunity in 50 years' 1
9:58 PM — Equal marriage advocate and NFL Football player, Chris Kluwe has spoken about the possible marketing and endorsement opportunities, surrounding the first openly gay NFL player, whoever that may be.
11th October 2012
US: NFL player starts controversy by tweeting a gay 'joke' 32
9:43 PM — An NFL football player in the US has been the subject of heavy criticism, after tweeting a joke which was considered by many as homophobic.


text: ""; ?> Guitar Tabs, Guitar Chords and Lyrics - Chordie guitar tabs, guitar chords and lyrics Artists Songs Public booksPublic My songbookSongbook ResourcesDiv Forum redknight songbook you rated this: Currently 2/5 Stars. Currently 2/5 Stars. 1 2 3 4 5 average: 2 by redknight10-hour Guitar Workout (Steve Vai)A Blues Improvisation (Misc Scales)A different corner (George Michael)A kind of magic (Queen)A Minor Pentatonic (Misc)A thousand miles (Vanessa Carlton)Adult Education (Hall And Oates)Adult Education v1 (Hall and Oates)Africa (Toto)Against All Odds (Phil Collins)Always Correct (Bon Jovi)Amor Amor Amor (Luis Miguel)Angels (Robbie Williams)Are You Gonna Be My Girl (Jet)Are You Gonna Be My Girl Full Correct (Jet)Babe (Styx)Best of both worlds (Van Halen)Breathe2 (Faith Hill)Bright Lights (Matchbox 20)Careless Whisper (George Michael)Do It For Love v1 (Hall and Oates)Dust in the wind (Kansas)Heaven Knows Acoustic (Rick Price)ITS TOO LATE (Carole King)Kissing A Fool (George Michael)Landslide (Dixie Chicks)Lately (Stevie Wonder)Notorious (Duran Duran)One Last Cry (Brian McKnight)Over my shoulder (Mike and The Mechanics)Paradise city (Guns N' Roses)Sarah Smile (Hall and Oates)Separate Lives (Stephen Bishop)Shes Gone (Hall and Oates)Shout at the devil (Motley Crue)Sometimes when we touch (Dan Hill)Tequila Sunrise (By The Eagles) Note: If you log in, you can add this book to your private collection and edit the content.Return to main list play their songs - buy their music - support the artists copyright © 2011 chordie guitar chords 5 popular songs Night Moves Bob Seger Country Roads John Denver Man On The Moon REM Mr Tambourine Man Byrds Lay Lady Lay Bob Dylan New songbooksAwesome ChristmasVarious songsEasy Playing Book 1Various songsjohaninplumaslake songbookVarious songsByardVarious songs- all public songbooks -


text: Pakistani Dramas Online in High Quality | Watch Hum Tv Dramas | Ary Digital Dramas | Geo Tv Dramas | Express Entertainment Dramas | Urdu1 TV Dramas | A Plus. A Plus is one of the Pakistani TV Channels who have snatched their share from the competitive media market in Pakistan. The Marketing strategies A PLUS has used by .... Pediatric Development Center provides evaluation and treatment services for children with known and suspected learning and/or developmental problems.. Videoixir milyonlarca videoyu tek çatı altında barındıran, can sıkıntısı giderecek bir sitedir.. The films listed below have been cited by reputable critics in multiple reputable sources as among the worst films ever made. Examples of such sources include .... TurboBit.net пÑÐµÐ´Ð»Ð°Ð³Ð°ÐµÑ Ð±ÐµÐ·Ð»Ð¸Ð¼Ð¸Ñное и бÑÑÑÑое облако Ð´Ð»Ñ Ñ ÑÐ°Ð½ÐµÐ½Ð¸Ñ Ñайлов, коÑоÑое позволÑÐµÑ .... GeliÅmiÅ arama seçenekleri ve sade yapısıyla etkili sonuçlar veren arama motoru.. About Me: served IAF for 20 years and for last 8 years with HYD based private firm. born in Hyderabad and working in Haridwar since 2007.international politics .... By John. 6735 views. You lucky this gate holding me back! By John. 20200 views. Copyright © 2013, FunMakers. All rights reserved.. Free Online Games at 108GAME.com. Awesome action games, puzzle games, adventure games, multiplayer games, skill games & best action games..


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Quantifying Everything For Great Justice
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How to Obtain Happiness
This Conversation Between a 13-Year-Old Coming Out to His ...
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text:
Over the past few years a lot of people have asked me where they could get a hold of my bedtime picture book Brave Little Monster. I would tell them that sometimes Scholastic makes it available through their book club in October, but that was hit and miss. Now I'm happy to say that you can purchase the paperback version of Brave Little Monster on Amazon. Yay!!!!
To top it off, an ebook version should be available in a few days as well. Enjoy!
Monday, October 27, 2014
Brave Little Monster Returns
Posted by Ken Baker at 9:56 AM Links to this post
Thursday, August 28, 2014
Writing Tip: Raising Plot Tension
Writing Instruction VideoSometimes beginning writers struggle to engage and maintain the reader's interest in their stories. Sometimes this happens because the protagonist solves plot conflicts too easily or too early in the story. Sometimes it happens because the opposite occurs, that it seems to take forever for the hero to solve the problem. This video demonstrates a writing technique that helps writers strike just the right balance in order to raise plot tension, thereby engaging and maintaining the reader's interest.
For teachers interested in using this video as part of creative writing lessons, the instruction video along with slide handouts that can be used to review the raising tension technique can be found at www.kenbakerbooks.com/raising-plot-tension.html.
Posted by Ken Baker at 12:42 PM Links to this post
No comments: Labels: author advice, lesson plan, plot, teachers, video, writing tips
Thursday, August 21, 2014
Why Plot Focus is Important in Picture Books and Short Stories
Writing Instruction VideoAs I have worked with various beginning picture book authors, a common problem that a lot of them run into is difficulty in conveying what their story is really about or going off in to many directions. Creative writing instructors in school may run into a similar problem when they assign students to write short stories. This writing instruction video on picture book plot addresses this issue.
If you enjoyed or found this writing instruction video useful, please share it with others. Thanks.
Posted by Ken Baker at 9:47 AM Links to this post
No comments: Labels: lesson plan, picture books, plot, short stories, teachers, video
Tuesday, August 19, 2014
Can Non-Artists Write Picture Books?
Picture Book Writing TipWanting to write picture books, but you can't even draw a straight line? Don't despair. This video writing tip tells why.
Posted by Ken Baker at 11:19 AM Links to this post
Thursday, August 7, 2014
How to Write a Great Picture Book
You have a great idea for a picture book. That's wonderful! Having a great idea is a good start. Having some writing experience is a big plus too. But writing a great picture book takes more than just having a great idea and some writing experience. Writing a great picture book requires work. If you're serious about writing a great picture book, it pays to do the following:
- Read a lot of current picture books. Believe me, picture books have changed since you were little. You have to familiarize yourself with the type, style and personality of picture books that children are reading today. Read as many picture books as you can that have been written in the past year or two.
- Do your research. Read different books on the ins and outs of writing a great picture book. The Complete Idiot's Guide to Publishing Children's Books by Harold Underdown is a great resource. There are also a lot of web sites and blogs with good information too, such as www.underdown.org, www.verlakay.com and www.taralazar.com.
- Attend writing conferences. Local and national children's writing conferences can be excellent resources for gaining much needed insights on how to improve your writing skills and understanding what makes a great a picture book great. Conferences are also great places to make contacts with other authors as well as editors and agents. You can find out about various conferences at www.scbwi.org/Regional-Events.aspx.
- Join a critique group. A critique group can give you objective advice on your stories. Once again, SCBWI is a good resource for finding out about local critique groups. Even if you're not a member of SCBWI, the regional coordinator for your area would likely be happy to tell you about critique groups in your area (Visit www.scbwi.org).
- Write a lot. Don't stop with one story. The more you write, the better your writing skills will become. Improve your writing skills even further by taking writing classes or attending writing workshops. Keep on writing.
Posted by Ken Baker at 9:03 AM Links to this post
2 comments: Labels: author advice, picture books, writing tips
Tuesday, July 1, 2014
State of the Children's Book Market
Kathy Temean posted on her blog an insightful look at the number and type of children's book contracts that the top 15 children's book publishers signed between June 2013 and June 2014 vs June 2012 and June 2013. The following are a few key takeaways that interested me most.
The full reports can be found on Kathy's site by visiting these links: Part 1, Part 2 and Part 3.
- Overall, Harper Collins and Scholastic held the number 1 and 2 spot for signing the most contracts (58 & 45)
- Sky Pony Press, a fairly new imprint not only rose to the number 6 overall position, but also signed the most picture book contracts (26) of the other publishers.
- Scholastic signed the most middle grade contracts (26)
- The report doesn't show who holds the top YA spot, which means that spot must be held by a publisher not in the top 15.
The full reports can be found on Kathy's site by visiting these links: Part 1, Part 2 and Part 3.
Posted by Ken Baker at 1:12 PM Links to this post
No comments: Labels: author advice, publishers
Thursday, June 5, 2014
What Makes a Great Picture Book - Tip 4
Pull Readers in Early
Too often beginning writers delay the introduction of their story's plot or conflict. Delaying that introduction can cause readers to quickly lose interest and not bother reading any further. A great picture book pulls the reader quickly into the story by introducing early on the problem faced by the main character – typically on the first spread and preferably on the very first line.
I WANT MY HAT BACK by Jon Klassen is a perfect example of this. In the very first sentence we learn the bear's problem. His hat is gone. The second sentence builds on the conflict telling us the bear wants it back. This immediate introduction to the story's plot pulls readers in quickly and has them turning page after page until they know how the problem ultimately gets resolved.
Of course, even worse than not introducing the conflict of the story early, is not introducing it at all. A great picture book needs an engaging plot and it needs to be introduced as early as possible.
Time is running out to register for the Picture Book writing workshop I'll be teaching at the WIFYR conference June 16-20.
Posted by Ken Baker at 8:38 AM Links to this post
1 comment: Labels: author advice, picture books, plot, writing tips
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Design your home
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Car News28 November 2014
Mercedes reveals its AMG Sport lineVijay Pattni
New performance range to sit just below full-fat AMGs, to take on BMW and Audi
Bike News
The Honda Gold Wing has landed in India
One of the most revered names in the world of motorcycling is here. Welcome everyone, to Honda's idea of the ultimate touring machine
Car News
Launched: BMW M3 and M4
The four-door M3 and two-door M4 are now in India
Car News
It's the new Nissan GT-R!
R35 Godzilla gets minor updates for 'more maturity'. Oh, and a hardcore 'Track Edition'
Car News
Watch a truck jump over an F1 car
Lotus and EMC claim new world record for longest ramp jump. You must watch this
Car News
New pic of 'baby' McLaren supercar
Latest teaser image proves McLaren's 'Sports Series' will have at least one door
Car News
New Mercedes C-Class arrives!
Petrol version comes first, costs ₹50 lakh on road...
Car News
Facelifted BMW M5 launched
BMW's brought the refreshed version of its four-door rocketship to India
Car News
Mitsuoka's incredible Orochi is dead
A moment of silence, please: Japan's maddest sports car bows out with barmy Evangelion Edition
Car News
TG.com chats with Gerrari Offroaders' Kabir Waraich
We speak with the first Indian to be headed for the Rainforest Challenge mother event in Malaysia


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Youth Mass to celebrate the start of Advent
Report CardsTerm
Term I Report Cards are in the mail along with our November newsletter! If you have any questions about the report cards, please don't hesitate to contact the school.
Here's the link to download the newsletter.
Graduation 2015
Our first graduation meeting was on October 28 - you can read the notes here. Our next meeting is on Tuesday, November 25 at 7 p.m. in the library.
The Grad Retreat will be on Thursday, November 13 and will cover, in detail, the requirements of Graduation Transitions, a mandatory 4-credit component of the graduation requirements. Attendance at this retreat is mandatory.
School Photos, part deux...
Any students who weren't able to have their photos taken at school on September 29, fear not! On October 22 in the afternoon, we will have a chance to go over to Christ the King Elementary School to have the photos taken. We will confirm the exact time closer to the 22nd.
Packages cost $35 plus $6 for a class picture (taken later in the year).
Parent-Student-Teacher Conferences
Parent-Student-Teacher Conferences will take place on Thursday, October 9 from 4-8 p.m. and Friday, October 10 from 8:30 - 12 noon.
Appointments are booked using an online system (available starting Saturday, October 4) or by calling the school at 667-5901 (starting Monday, October 6).
The online system (http://vanier.schoolappointments.com) requires parents/guardians to create an account and requires an access code which is vanier2014
Here are some additional instructions:
Interim Reports and an October newsletter went out in the mail this morning and should arrive at your household within a few days.
Information for booking parent-teacher interviews can be found above. You can book online (starting Saturday, October 4) or by calling the school at 667-5901 (starting Monday, October 6).
September 28th, 2014
School Photos
School photos will take place on Monday, September 29. All students will have their photos taken, however students will be issued an envelope this week to indicate whether they wish to purchase a package. All the details of the costs will be included on the envelope.
[NOTE: Cats and lasers will not be photo options! :-) ]
[UPDATE: Turns out, if you're the principal, you can have a cat.]
The Cafeteria is Now Open!
The cafeteria is open starting Monday, Sept. 22.
Sales start at first break with regular offerings of breakfast items: oatmeal, wraps, English muffin sandwiches and bagels.
Lunch items include sandwiches, soup and daily specials.
Prices range from $1.25 to $7.00
Menus for the upcoming week will be posted on Thursdays so you can plan ahead.
Thank you for your patience as we sorted this out. Enjoy!
First Mail-out of the year
The office will be mailing out our first package of the year that includes a number of important documents, including:
Again, please submit the forms back to the office with school fees by the end of September to be eligible to win an iPad mini!
For those of you who can't wait to read the newsletter...


text: LATEST FROM THE AM870 LOCAL NEWS DESK More Local News >>> Man Pleads Not Guilty in Murder Over Parking Space at Santa Fe Swapmeet Posted on: November 21, 2014 A man is pleading not guilty after an argument over a parking space ends in murder. Reggie Cervantes pleaded not guilty Thursday to stabbing a woman to death in the parking lot of a Santa Fe Springs swap meet. Read More Phillip Moreno Family Suing Drunk Drug Counselor Sherri Wilkins for Deadly Hit-and-Run Posted on: November 21, 2014 Family is suing after a deadly hit-and-run in Torrance. Sherri Wilkins, a drug and alcohol abuse counselor, had been driving drunk in 2012 when she slammed her car into 31-year-old Phillip Moreno. Read More Sangin Miller Oh, Former Buena Park Mayor, Sentenced for Lying to DMV Posted on: November 20, 2014 Sangjin Miller Oh has been sentenced to six months in jail and 200 hours of community service after being convicted of lying to the DMV. The former Buena Park mayor was accused of getting a drivers license under a fake name to register cars and hide other assets to avoid paying child support to his ex-wife. Read More Mira Costa High Reopened after Threatening Social Media Posts Posted on: November 20, 2014 Mira Costa High School in Manhattan Beach will be open today after a threat on social media shut it down. Investigators say they have identified and interviewed a girl who is responsible for at least one of the postings on Yik Yak, which is an anonymous messaging smartphone app. Read More Santa Ana Homeless Shelter Plans Dropped by Orange County Posted on: November 19, 2014 Orange County is dropping a $3.6 million plan to build a year-round shelter for the homeless. Read More


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2012 Holiday Gift Guide: Tech and Gadgets
Make life easier—or just more fun—with these cool gifts for gamers, girlfriends and everyone in between.
Logitech Harmony Touch Remote
The truth is that this latest universal-remote offering from Logitech packs in more features than you will likely ever use. The ones that you will use, however, will transform the way you perceive the media in your home. After setting up the device with the accompanying software and taking it for a spin, you will cease to view your media stack as a TV, cable box, Xbox, and Apple TV, but rather as a menu of experiences that you command with effortless swipes and taps on the vibrant, color touch screen of this intuitive and highly ergonomic controller. The virtual, scrolling channel guide with shortcuts to your favorite stations is enough alone to justify this bad boy.
($250; Logitech.com)
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- 8 Ways to Stay Healthy This WinterWhat does it really take to build your defenses against the common cold?
- The 5 Toughest Yoga Positions for GuysTackle them to achieve the ultimate in strength and balance.


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- 7-Keto
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- Acure Organics
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Aveeno, Active Naturals, Positively Smooth Shave Gel, 7.0 oz (198 g)
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- Product Code: AVO-03859
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- Dimensions: 2 x 2 x 8.1 in, 0.6 lbs (0.27kg)
Expiration Date: Either this product has no expiration date, or the manufacturer has not provided us with an expiration date.
Madre Labs, Pycnogenol Serum (Cream), 1 oz (28 g)
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Aveeno Active Naturals Positively Smooth Shave Gel
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Wet area to be shaved. Put small amount of gel on fingertips and rub over skin to produce a rich lather. Shave and rinse. For best results, use in combination with Aveeno Positively Smooth Moisturizing Lotion.
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Water, palmitic acid, triethanolamine, isopentane, sorbitol, stearic acid, sorbitan stearate, glycerin, isobutane, glycine soja (soybean) seed extract, benzyl alcohol, fragrance, sunflower seed oil glyceride, dimethicone PEG-8 benzoate, hydroxyethylcellulose, phenoxyethanol, hydroxypropyl methylcellulose, methylparaben, propylparaben, panthenol, tocopheryl acetate, ethylparaben, glycine soja (soybean) seed protein extract, allantoin, aloe barbadensis leaf juice.
Flammable, contents under pressure. Do not puncture or incinerate or store at a temperature above 120°F. Use only as directed. Intentional misuse by deliberately concentrating and inhaling aerosol products can be harmful or fatal. Do not use near flame or spark or while smoking. Keep out of reach of children.
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Nigel King
From Wikipedia, the free encyclopedia
Nigel King is a British professional yachtsman and has competed in several Volvo Ocean Races, the Jules Verne Trophy, Olympic trials and many classic yacht races around the world.
King acts as a coach and mentor to the Volvo RYA Keelboat Programme, which trains Britain's young talented sailors. In addition, he is a passionate and powerful motivational speaker for both large and small groups, as well as having run successful leadership and business improvement programmes. King is currently embarking on a challenge for the Solitare du Figaro 2007, and is building a campaign for the 2008/2009 Vendee Globe solo round the world race.
King and his wife live in Lymington, Hampshire.
Nigel King Preparing for the Solitaire - Sail-World April 2007


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You're leaving Wedding Paper Divas to see the Deal of the Day at our parent site, Tiny Prints.
You won't be able to dismiss this by usual means (escape or click button), but you can close it programatically based on user choices or actions.
"As always, I am very happy with the invitations I ordered. WPD offers so many styles and designs! I have always been able to find one to match the event I am planning. Most impressive with this order is that I selected the New Super Rush delivery. I had my order in LESS THAN 36 HOURS FROM WHEN I PLACED THE ORDER! I will always return to WPD and will recommend them to all my friends."
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"These invitations are perfect! I got the pearl finish on the paper and it really gives it a very expensive look. I added a photo on the back and the quality and color of the image is spot on. The ordering process was easy, cost was fair and delivery was quick. I can't wait for everyone to see them! Great job Wedding Paper Divas!!!"


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When Somebody Says, That Cant Be Done, I Smile. .....
Text Illustration shared by SermonCentral
April 2007
Scripture: Daniel : (add scripture)
Tags: Workplace Balance (add tag)
Category: Quotes
"When somebody says, That cant be done, I smile. Thats about all I need to go after it. Im not a risk taker. Im a risk pervert."
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CCHL 2012-2013 season - part II (Mod warning in Post 30)
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Join Date: May 2010
Posts: 83
vCash: 500
Originally Posted by
I didn't say that all three were a problem in KV. I said that there was a problem "on the ice" with one of them. Actually, from what I heard, all three are good guys etc. But, if many of the scratches, 3rd and 4th line guys felt that the one kid was played way too much, with not great stats to back that much icetime.
Also, i hope that someone on KV has a chat with Seether and TELL him stop stop sulking and play the game. I have been to 4 or 5 games where he looks like a spoiled bratt if he gets knocked off the puck or someone doesn't pass to him. Time for him to grow up a little.
Originally Posted by
Ottawa Guy
He is a 17 year old kid, by definition he has a lot of growing up to do as do many other 17 year olds in the league, these kids go from being the stars on thier minor hockey to junior where not evrything goes thier way. Not all mature at he same time, often they do not even understand the message they are sending with thier body language....give the KID a break, there have been lots of players that playing in CP has not worked out for.
I think Hockieguy has a point. Sure he's 17, but he's not talking only about CP. Take a look at him in KV. He does seem to have an attitude and frankly it doesn't seem to change regardless of who he is playing with!
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text: ESPN Feed: top five http://assets.espn.go.com/i/tvlistings/tv_espn_original.gif ESPN en-us 10 ESPN Inc. http://espn.go.com/ Copyright 2010 ESPN Inc. Daniel Bodin, Aleksander Nordgaard and Jimmy "Blaze" Fejes finished 1-2-3 in the freestyle comp at Sweden X last weekend, April 18-19, at the Klappen ...]]> April 25, 2008 11:19:56 PDT Check out what tunes this renowned dirt jumper digs on.]]> December 26, 2007 04:24:02 PST A DJ who stays in the know, the Muska hit us up with his top five albums of all time, and why he loves them so much. Crank it up, sucka.]]> October 16, 2007 05:28:29 PDT Bright new Swatch TTR World No. 1 after halfpipe win at Nissan X-Trail Nippon Open.]]> March 04, 2008 04:24:28 PST WX12 Men's Snowboard SuperPipe Preview: Which of these five pipe powerhouses will have the focus and form to wrangle the U-ditch title at WX12? Two top industry-types weigh in.]]> January 11, 2008 11:00:45 PST wbbpjb]]> July 10, 2007 10:21:55 PDT Jamie Anderson wins gold; sister Joanie takes silver.]]> April 14, 2005 10:22:20 PDT Elissa Steamer wins the first X Games Women's Skate Street event.]]> August 06, 2004 14:02:43 PDT Ludacris and Kanye West slated to perform.]]> March 16, 2004 11:46:32 PST


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Heaven Scent Organic Tea Lights - 24 Pack
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Heaven Scent Organic Tea Lights are versatile and stylish. The tea lights burn cleanly and brightly, perfect for oil burners and soft, pretty lighting. This jumbo pack gives you great value and Heaven Scent Tea Lights are good for the environment too. Made from 100% organic palm wax, they are a vegan alternative to paraffin wax and release fewer harmful chemicals, so you can enjoy your candles in harmony with the natural world.
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Aspen Condo Rental Photos and Description
3 Bedrooms, 2 Bathrooms (Sleeps 6)
This cozy 3-bedroom, 2-bath economy condominium features mountain views and is only two blocks from the Silver Queen Gondola and even closer to downtown Aspen.
Amenities include floor-to-ceiling windows and a wood-burning fireplace in the main living area.
Complex amenities at the Durant Condominiums include an on-site heated pool and two hot tubs; an outdoor grill; laundry room; complimentary Aspen airport transfers; on-site free parking; and free wireless internet access.
The Durant Condominiums offers ski-in access from Aspen Mountain!
All Frias Properties of Aspen guests receive complimentary passes to the Aspen Club & Spa, the valley's premier full-service spa and workout facility.
(Passes to the Aspen Club & Spa can be obtained from any Frias front desk during regular business hours.)
- Suitability:
- pets not allowed