text:
i take meds for hypertension and diabetes should there be any problems ? might it help? i've never taken alka seltzer, what is it really good for?
What side effects can one expect if taking alka seltzer only one time should it help my stomach?
- Posted:
- 14 Sep 2010 by I feel sick
- Topics:
- diabetes, type 2, hypertension, side effect, alka-seltzer original
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Answers (1)
14 Sep 2010
If it's just regular Alka-Seltzer Effervescent Tablets then common side effects include: Heartburn; nausea; upset stomach.
Severe side effects include: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black stools; confusion; diarrhea; dizziness; drowsiness; hearing loss; ringing in the ears; severe stomach pain; unusual bruising; vomiting.
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Pichia or extracts of Pichia may be used in the treatment of human beings and animals for the purpose of non-specific immunostimulation, potentiation of the action of antibiotics and increasing vaccine activity.
1. A process for treating bacterial or viral infection, comprising oral administration to a patient in need thereof of about 20-500 mg/day of a water-insoluble Pichia glucan having a molecular weight in the range of about 200,000 to 230,000, consisting essentially of branched beta (1--3) and beta (1--6)-D-glucans having one beta (1--6) bond for 9 to 10 glucose units, substantially free from: (i) proteins, lipids and mannans capable of removal by dilute alkaline treatment; and (ii) glycogens and soluble glucans capable of removal by adjusting the pH to between about 2 to 5 with a strong acid treatment.
2. A process for treating bacterial or viral infection, comprising parenteral administration to a patient in need thereof of about 5-100 mg/day of an injectable suspension Pichia glucan having a molecular weight in the range of about 200,000 to 230,000, consisting essentially of branched beta (1--3) and beta (1--6)-D-glucans having one beta (1--6) bond for 9 to 10 glucose units, substantially free from: (i) proteins, lipids and mannans capable of removal by dilute alkaline treatment; and (ii) glycogens and soluble glucans capable of removal by adjusting the pH to between about 2 to 5 with a strong acid treatment.
3. A composition for treating bacterial or viral infection, comprising an anti-infectively effective amount of a water-insoluble Pichia glucan having a molecular weight in the range of about 200,000 to 230,000, consisting essentially of branched beta (1--3) and beta (1--6)-D-glucans having one beta (1--6) bond for 9 to 10 glucose units, substantially free from: (i) proteins, lipids and mannans capable of removal by dilute alkaline treatment; and (ii) glycogens and soluble glucans capable of removal by adjusting the pH to between about 2 to 5 with a strong acid treatment.
4. A composition according to claim 3, containing 20-500 mg of the glucans in an oral dosage form.
5. A composition according to claim 3, containing 5-100 mg of the glucans, in an injectable suspension.
6. A composition according to claim 3 in aerosol form.
7. A composition according to claim 3, wherein the glucan is extracted from Pichia fermentans.
This application is a continuation of U.S. application Ser. No. 680,579, filed Dec. 11, 1984, now abandoned, which is a continuation-in-part of Ser. No. 619,887, filed June 12, 1984, now abandoned, which in turn is a continuation-in-part of Ser. No. 315,498, filed Oct. 27, 1981, now abandoned, which in turn is a continuation of Ser. No. 114,327, filed Jan. 22, 1980, now abandoned.
The present invention relates to the use of Pichia, in particular Pichia fermentans, or extracts of Pichia as such, as a medicament.
Pichia is a yeast belonging to the Saccharomycetaceae family and to the Saccharomycoideae sub-family comprising numerous genera. These genera are defined for example in "The Yeasts" (LODDER, North Holland Publishing Company, 1970, pages 405 to 554). The species Pichia fermentans, which has been more especially studied by the Applicants, is known and can be obtained form several collections of micro-organisms, for example from the CENTRAALBUREAU VOOR SCHIMMEL CULTURES (DELFT, Netherlands), under No. CBS 187.
To the Applicants' knowledge, Pichia has never been studied with a view to therapeutic use. Yeasts belonging to a different genus, such as Saccharomyces cerevisiae, have been used in therapeutic applications, in particular as protective or regenerative agents for the intestinal bacterial flora.
Moreover, certain authors have studied extracts of Saccharomyces cerevisiae or their glucanes as regards their effect on the reticulo-endothelial system (RIGGI and Di Luzio, Am J. Physiol. (1961) 200, 2, pages 297-300) or as regards their anti-tumor action (HAMURO and colleagues, C.A., (1978), 89, 40 704 b).
Now, the Applicants have found that Pichia, notably Pichia fermentans as well as its extracts, in particular the insoluble glucanes, have exceptional pharmacological properties that justify their use as medicaments in the treatment of infectious diseases: non-specific immunostimulation, potentialisation of the action of antibiotics, and increase in the activity of vaccines.
The Pichia strains may be cultivated and grown in a known manner on culture and fermentation media conventionally used for yeasts. The cells obtained may be dried at 50� in vacuo, but are preferably lyophilised (freeze dried).
The extracts according to the invention, which are in principle insoluble glucanes, may be isolated from the cell walls of Pichia, for example by the method described by Bell and Northcote (J. Chem. Soc. (1950), p. 1944-47), if necessary modified, for example according to Peat and colleagues (idem, 1958a, p. 3862-3868). The principle consists of removing first the proteins, lipids and mannans by alkaline treatment (for example with a diluted strong alkali such as sodium hydroxide), and then the glycogen and the soluble glucanes by acid treatment (for example with acetic or hydrochloric acid), from the cellular mass obtained by fermentation. The extract may be dried by atomization.
The following examples illustrate the preparation of these products.
(a) Preparation of yeast sediments
The yeast sediment (the sediment placed in the bottom of the vat to start fermentation) is prepared from the stock culture for the Pichia fermentans strain. The latter is obtained by incubating yeast for 48 hours at 30� C. on sloped agar containing:
______________________________________Medium (1) yeast water 500 ml pancreatic peptone 2 g starch syrup 10 g agar 18 g tap water, in an amount 1 liter. sufficient to make up______________________________________
The culture is separated from the sloped agar via a tube, using about 10 ml of sterile physiological serum. The suspension thus obtained is added, while maintaining sterile conditions, to a 6-liter volume Erlenmeyer flask containing 1.5 liter of fermentation medium of the following composition:
______________________________________Medium (2) glucose 10 g yeast extract 2 g ammonium sulphate 5 g monopotassium phosphate 5 g magnesium sulphate (7 H2 O) 0.05 g calcium chloride 0.01 g ferrous sulphate (7 H2 O) 0.01 g potassium chloride 0.01 g tap water, sufficient to 1 liter. make up______________________________________
Incubation is carried out for 24 hours at 27��1� in a rotary agitator operating at about 115 revs./minute.
(b) Fermentation
The contents of the Erlenmeyer flask as obtained above (about 3 liters) are inoculated in a sterile fermentation vat containing 100 liters of medium (2) described above. Fermentation is carried out for 20 hours while aerating at a rate of 20 m3 /hour. The contents of the vat are then centrifuged in order to collect the mass containing the Pichia cells.
2.8 kg of a cellular mass are obtained (74% moisture).
255 g of cells ready for use are obtained by drying in vacuo at 50� C. 1 kg of the cellular mass obtained in Example 1.
An alternative, which can be used in order to obtain a product that is easier to store and use, is as to lyophilise the cellular mass obtained in Example 1; in this way 252 g of utilisable cells are obtained from 1 kg of cellular mass.
1 kg of freshly centrifuged cellular material obtained according to Example 1 is treated with 3 liters of a 6% sodium hydroxide solution for 11/2 hours at 80� C.; the residue is collected by centrifugation (4000 revs./minute for 15 minutes) and is then treated with 5 liters of a 3% sodium hydroxide solution for 18 hours at ambient temperature. The solution is recentrifuged and the insoluble product is retreated with a 3% sodium hydroxide solution for 2 hours at 80� C. The solution is centrifuged and the centrifuge deposit is taken up in 3 liters of water. The suspension thus obtained is adjusted to a pH of 4.5 with acetic (or hydrochloric) acid and is heated at 80� C. for 2 hours while stirring. The residue obtained by centrifugation is washed 3 times with 1 liter of boiling water each time, is taken up in 2.5 liters of a 0.02M sodium acetate solution, and is then autoclaved at 1 bar atmosphere for 11/2 hour.
The insoluble fraction is washed with water, then with ethanol and acetone, and is dried in vacuo at a maximum temperature of 50� C. The product obtained is ground and provides 15.5 g of a cream colored powder.
An alternative method is lyophilisation, and 14.2 g of extract can be obtained starting from the same quantity of cells.
A further method is atomization, and 15.3 g of extract can be obtained starting from the same quantity of cells. This extract has a particle size between 5 and 30μ, which enables use without further treatment.
Analysis: C=45.15%; H=7.42%; 0=47.4% N<0.2% P: absent.
The action of pancreatic amylase on the extract releases only a few traces of reducing compounds, thus indicating the absence of glycogen.
The extract according to the invention is remarkable in that it is insoluble in water, alkaline or acid diluted solutions, and the usual organic solvents such as ethanol, diethyl ether, ethyl acetate, acetone, chloroform, etc.
It is found however that it is very slightly soluble in dimethyl sulphoxide (DMSO).
Specific rotary power: |α|D 20 ≅-60� (C=0.2; DMSO).
Infra-red: the spectrum obtained using a KBr prism has a characteristic absorption band at 885 cm-1.
The presence of such IR absorption band is proof that the Pichia extract contains β bonds and specifically β1--3 bonds. The partial hydrolysis of the extract confirms the presence of a major part of β1--3 bonds and also of some β1--6 bonds.
According to the methylation test (Hakomori method, Methods of Enzymology 28 178-195, 1972), the observed presence of sugar bonded in ≢1--3--6 means that the Pichia extract in fact has a branched structure, which is believed to correspond to the following formula (presumed formula): ##STR1## in which G=glucose unit,
x+y+z=about 40 and
n=about 26.
It is to be noted that the above formula does not indicate the exact position of the β1--6 bonds within the chains, which simply have been placed so that the above proportion (one β1--6 bond for 9 to 10 glucose units) is satisfied.
The polymerization degree as determined according to the method of Manners et al. (Manners, Masson, Patterson, Carbohyd. Res. 17 (1971) 109-104), is 1320 (�100) which corresponds to a molecular weight of about 200,000 to 230,000.
Thus the Pichia extract according to the invention, which will be called "glucans" hereafter in the text, consists essentially of branched β (1--3)- and β (1--6)-D-glucans comprising about one β (1--6) bond for 9 to 10 glucose units, said glucans having a molecular weight of about 200,000 to 230,000.
The Pichia yeasts, in particular Pichia fermentans as well as the glucanes extracted therefrom, have been subjected to pharmacological tests.
No toxicity was observed when Pichia fermentans or its glucanes were administered orally to mice.
The LD50 of these glucanes administered intraperitoneally is greater than 500 mg/kg.
The animals used were female IOPS IFFA CREDO mice weighing 18-20 grams and fed for one week before the test on a diet containing no yeast but containing the necessary dosage of vitamins.
The mice were split up into 2 batches each containing 10 animals:
1 infected control batch
1 infected batch treated with Pichia.
The animals were infected intravenously with a highly pathogenic strain of Staphylococcus aureus (Institut Pasteur Strain No. 54 146), and the Staphylococcus aureus used was reactivated by being passed through mice before the test. A culture in nutrient broth incubated for 16 hours at 37� C. was diluted to 1/100 and then used to infect the mice. Each mouse received intravenously, under these conditions, about 6�105 virulent germs.
The experimental schedule was as follows:
______________________________________Control batch Treated batch______________________________________Day - 3 0.2 ml of physiological 0.2 ml of a serum administered orally suspension ofDay - 2 to each mouse Pichia containing 3 g/20 ml, adminis- tered orally toDay - 1 each mouseDay - 0 STAPHYLOCOCCAL INFECTION by intravenous routeDay 0 to the same as day - 3 the same as day - 3Day + 7 to day - 1 to day - 1______________________________________
The number of dead mice in each batch is noted every day. This test was carried out 5 times and the following results, expressed in terms of the number of surviving mice, were obtained.
______________________________________ Control batch Treated batch______________________________________Test No. 1 1/10 3/10Test No. 2 3/10 10/10Test No. 3 1/10 2/10Test No. 4 3/10 1/10Test No. 5 0/10 6/10% survival 16% 44%______________________________________
As can be seen, the number of dead mice in the treated batch is less than the number of dead mice in the control batch.
In view of the virulence of the injected pathogen, a substantial protection is conferred by the oral administration of Pichia.
This protection can be attributed to a non-specific immunostimulation.
The animals used were female IOPS IFFA CREDO mice weighing 18-20 grams, fed for 8 days before the test on a diet free from yeasts but containing the necessary amount of vitamins.
The mice were divided into 2 batches:
1 infected control batch
1 infected batch treated either with Pichia or with its glucanes.
The tests were carried out on mice infected intravenously with about 1�106 Staphylococcus aureus pathogens (Institut Pasteur Strain 54.146) prepared as described previously.
The treatment was given intraperitoneally.
for Pichia fermentans, in a dosage of 50 mg/kg
for the glucanes of Pichia fermentans, in a dosage of 10 mg/kg.
The experimental schedule was as follows:
______________________________________Control batch Treated batch______________________________________Day - 7 Intraperitoneal Intraperitoneal injection of 0.2 ml of injection of 0.2 physiological serum ml of a per mouse suspension of Pichia or glucanesDay - 4 2nd injection, 2nd injection, as above as aboveDay 0 Staphylococcal infection by intravenous route______________________________________
The number of dead mice in each batch is noted every day.
The following tables show the number of surviving animals for several tests.
______________________________________(A) - with whole cells of Pichia fermentans Control batch Treated batch______________________________________Test No. 1 2 6(on 10 mice)Test No. 2 1 5(on 5 mice)Test No. 3 0 8(on 10 mice)% survival 12% 76%______________________________________
______________________________________(B) - with glucanes of Pichia Control batch Treated batch______________________________________Test No. 1 1 9(on 10 mice)Test No. 2 0 3(on 5 mice)Test No. 3 0 8(on 10 mice)Test No. 4 2 7(on 10 mice)% survival 8.5% 77.2%______________________________________
As can be seen, the number of dead mice is less in the treated batches than the number of dead mice in the control batches, whether treatment is effected with whole cells of Pichiafermentans or its glucanes.
Given the virulence of the injected pathogen, intraperitoneal injection of Pichia or its glucanes confers a high degree of protection.
This protection can be attributed to a non-specific immunostimulation.
Cultures of Pichia kluyveri (ATCC 9768), Pichia membranae faciens (ATCC 26288 and CBS 107) and Pichia polymorpha (ATCC 18577 and CBS 6.2) are grown and treated in the same manner as described above in Example 1 for Pichia fermentans. Whole cells of Pichia are lyophilized as in Example 2 above, and glucanes thereof are obtained by the process of Example 3 above. The immunostimulative effect produced through oral treatment is tested by the method described previously. The results are shown in the table below:
______________________________________ PichiaCon- Pichia membranae Pichiatrol kluyveri faciens ATCC polymorphabatch ATCC 9768 26288 ATCC 18577______________________________________Test No. 1 2/10 4/10 3/10 4/10Test No. 2 1/10 3/10 3/10 3/10Test No. 3 1/10 5/10 6/10 4/10Test No. 4 0/10 5/10 1/10 2/10Test No. 5 3/10 4/10 5/10 6/10% survival 14% 42% 36% 38%______________________________________
The immunostimulative effect produced through intraperitoneal treatment is tested by the method described previously. The results are shown in the table below:
______________________________________Control ATCCBatch ATCC 9768 ATCC 26288 18577______________________________________Test No. 1 1/10 7/10 6/10 8/10Test No. 2 2/10 8/10 8/10 8/10Test No. 3 0/10 7/10 6/10 5/10% survival 10% 73% 67% 70%______________________________________
The animals used were female SPF IFFA-CREDO mice weighing 18-20 grams, fed for one week before the tests on a diet free from yeast but containing the necessary dosage of vitamins.
These mice were divided into 4 batches each containing 10 mice.
batch 1: infected control batch
batch 2: antigen control batch ("vaccine")
batch 3: received the specific antigen and were also infected
batch 4: as per batch 3, but treated in addition with Pichia glucanes.
The antigen in this case is a Staphylococcus aureus culture (Institut Pasteur 54.146) administered in a non-lethal dosage.
The culture is grown for 16 hours in nutrient broth and is then diluted immediately before vaccination to 1�10-4, representing about 1�104 germs/ml.
The mice of batches 1, 3 and 4 were infected with a highly pathogenic strain of reactivated Staphylococcus aureus (Institut Pasteur 54.146). A nutrient broth culture incubated for 16 hours at 37� was injected undiluted and intravenously to infect the mice (i.e. 1�108 germs/ml).
______________________________________The experimental schedule was as follows: Batch 4Batch 2 Batch 1 Batch 3 vaccinated +control + infection vaccinated + infected +Antigen control infected Glucanes______________________________________Day - 9 0.2 ml of 0.2 ml of 0.2 ml of 0.2 ml of 104 germs/ physiolog- 104 germs/ 104 germs/ ml admin- ical serum ml admin- ml admin- istered adminis- istered istered I.V. tered I.V. I.V. I.V.Day - 6 0.2 ml of 0.2 ml of 0.2 ml of 0.2 ml ofDay - 5 physiolog- physiolog- physiological 10 mg/kg/Day - 4 ical serum ical serum serum admin- day ofDay - 3 adminis- adminis- istered I.V. glucanesDay - 2 tered I.V. tered I.V. per day administer-Day - 1 per day per day ed intra- peritoneallyDay 0 0.2 ml of infection by intravenous route physiolog- (0.2 ml of culture containing ical serum 108 germs/ml) adminis- tered I.V.______________________________________
The number of dead mice in each batch is noted every day. The following table gives the survival rate as a function of time.
______________________________________ Batch 4 Batch 1 Batch 2 Batch 3 Antigen +DAYS AFTER infection Antigen Antigen + infection +INFECTION control control infection Glucanes______________________________________1st day 0/10 10/10 9 102nd day 7 93rd day -- --4th day 3 35th day -- --6th day 1 --7th day -- --8th day 0 --End of test 0/10 10/10 0/10 3/10______________________________________
100% of the animals infected with a superlethal dose of Staphylococcus aureus were dead within 24 hours.
The animals that had been vaccinated once 9 days before the superlethal infection are slightly protected since they all die only after 8 days.
As may be seen from the results in the tables, treatment by glucanes administered intraperitoneally in addition to vaccination protects the animals not only by increasing the survival time but also by reducing the mortality rate.
Given the very high degree of virulence of the injected pathogen, the potentialization conferred by the glucanes on a specific prevaccination is quite considerable. This potentialization can in this case also be attributed to an immunostimulation.
In this test, a therapeutic treatment for 2 days using glucanes in a dosage of 10 mg/kg was combined with a short-term course of antibiotic treatment (single injection of penicillin) in a normal therapeutic dosage (30,000 units/kg).
The animals used were the same strain as in the previous tests, and were fed on the same diet.
The mice were divided into 4 batches each containing 5 mice:
batch 1: infection control
batch 2: treated with Pichia glucanes
batch 3: received 1 injection of penicillin
batch 4: received Pichia glucanes and 1 injection of penicillin.
The test was carried out on mice infected intravenously with about 1�106 reactivated Staphylococcus aureus pathogens (Institut Pasteur 54.146).
A culture in nutrient broth incubated for 16 hours at 37� C. as diluted to 1/100 and used to infect the mice.
The experimental schedule was as follows:
______________________________________Infection Penicillin +control Glucanes Penicillin glucanes______________________________________Day 0 STAPHYLOCOCCAL INFECTION BY INTRAVENOUS ROUTEDay + 1 nothing Intraper- Intramus- Intraper- itoneally: cularly: 0.2 itoneally: 0.2 0.2 ml of a ml of a ml of a suspension solution of suspension of of glucanes, penicillin, glucanes 10 mg/kg 30,000 IU/kg containing 10 mg/kg + intramuscular- ly, 0.2 ml of a solution of penicillin, 30,000 IU/kgDay + 2 nothing Intraper- nothing intraper- itoneally: itoneally: 0.2 ml of a glucanes suspension of glucanes, 10 mg/kg______________________________________
The number of dead mice is noted every day, and the following table gives the number of surviving mice observed in each batch.
______________________________________ Penicillin Glucanes +Controls Glucanes alone alone Penicillin______________________________________1/5 3/5 2/5 4/5______________________________________
As before, protection is conferred by Pichia glucanes alone, although used as a therapeutic treatment in this test (3/5).
Penicillin conferred a slight protection on the animals (2/5).
The combination of glucanes with the same dosage of penicillin potentialized the antibiotic action of the latter (4/5).
The tests described above show that the administration of Pichia fermentans or its glucanes on the one hand reduces, by non-specific immunostimulation, the mortality rate in animals infected with a pathogen, and on the other hand potentializes the action of antibiotics and vaccines. This yeast can thus be used to reinforce the resistance of an organism to infectious agents and to improve the immune defense system.
Since the Pichia fermentans yeasts and glucanes extracted therefrom are non-toxic, they may be used in the prevention and/or treatment of acute or chronic infectious diseases, in particular diseases of the oto-rhino-laryngeal and/or pulmonary systems, but may also be used to treat any other illness of viral or bacterial origin.
Pichia fermentans and its glucanes may be used as medicaments alone or in combination with one or more antibiotics.
The whole cells of Pichia may be administered orally in daily dosages of 100 to 2000 mg (dry product) per day, preferably in capsules containing the lyophilised cells and, if desired, with convention excipients, or as ampules for oral consumption, the cells being suspended in their culture medium.
______________________________________Example of the composition of a capsule:______________________________________Lyophilised cells of Pichia fermentans 50 mgLactose 7 mgMagnesium stearate 2 mgIcing sugar in an amount to make a 150 mgcapsule containing______________________________________
The Pichia glucanes may also be administered orally (a gastroresistant form) in daily dosages of 20 to 500 mg, preferably 50-200 mg, or may also be used in the form of injectable suspensions in an amount of 5 to 100 mg per day. The use of these glucanes in the form of skin creams or aerosols may also be considered. An aerosol dosage of about 5-50 mg per day, preferably 5-10 mg per day, is contemplated. The contemplated treatment involves daily dosages for 5 to 8 days, repeated after one week if necessary. The oral form is contemplated for general use in treating infectious diseases. The aerosol form is contemplated for treatment of diseases of the upper respiratory and pulmonary system, particularly for immuno-depressed subjects, such as post-operative, radiation treatment and burn victim situations or those suffering from chronic respiratory diseases.
Example of the composition of an injectable suspension:
______________________________________Micronized glucanes of Pichia fermentans 0.010 g(particles < 50 μm, of which 80% < 10 μm)Polysorbate 80 0.025 gPolyvinyl pyrrolidone 0.025 gMonosodium phosphate 0.025 gSodium chloride, in an amount sufficient toproduce an isotonic solutionSodium merthiolate 0.0002 gNon-pyrogenic distilled water, in an amountsufficient for 1 5 ml ampule for injection______________________________________
Example of an aerosol
______________________________________Micronized glucanes (particles < 50 μm, of 0.050 gwhich 80% < 10 μm)Polysorbate 80 0.2 gPolyoxyethylenated oleic glycerides 1 gMonosodium phosphate 0.1 gSodium chloride in an amount sufficientto give an isotonic solutionSodium merthiolate 0.0008 gPurified water, in an amount sufficient 20 mlto make______________________________________
Example of the composition of an oral form
This form consists in neutral microgranules on which micronized glucanes are fixed and which are protected by three successive Eudragit L coatings. The composition of said form is as follows:
______________________________________Micronized glucanes 10 gNeutral microgranules 20 gTalc 3 gPolyethyleneglycol 6000 (PEG 6000 MW - 1 gabout 5600-7000)Erythrosine lake (40% FDC) 0.15 gEudragit L (an anionic polymer of methacrylic 25 gacid and methyl methacrylate dissolved inisopropanol and produced by Rohm Pharma)______________________________________
The neutral microgranules may be a 70/30 mixture of sucrose and starch on which the active substance is applied by successive coatings. An example of a suitable material is that sold under the trademark "NUPAREL" by Edward Mendell, Inc.
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Overpriced drinks, $27 a night parking, not very caring staff, rooms are remodeled but really awkward. Had to stretch and see the ONLY mirror in the room and unless your 4'9" you will have to bend over. Pressure washing at 9:12 am.
So many other places in Key West to stay. We have been staying here since 1995 and this was our last.
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Posted December 08, 2012 on AP on Fox
Jets tight end Dustin Keller will miss New York's game at Jacksonville on Sunday because of a sprained left ankle. Keller was listed as doubtful Friday after injuring his ankle last Sunday in the Jets' 7-6 win over the Arizona Cardinals. He is second on the team with 28 receptions despite missing four games earlier this season with a hamstring injury. Keller, who sat out practice all week, will likely be replaced in the starting lineup by backup Jeff Cumberland, who has 21 catches this season. The Jets will also be without backup defensive tackle Damon Harrison, who turned an ankle during practice Thursday. Backup quarterback Tim Tebow, recovering from two broken ribs, was expected to be a game-time decision. --- Online: http://pro32.ap.org/poll and http://twitter.com/AP-NFL
Original Story: http://msn.foxsports.com/nfl/story/Je...
PLAYERS: Dustin Keller, Jeff Cumberland, Damon Harrison, Tim Tebow
TEAMS: New York Jets, Arizona Cardinals
TEAMS: New York Jets, Arizona Cardinals
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@article {S. Boja:2011-04-01T00:00:00:1570-1646:31,
author = "S. Boja, Emily",
title = "Quantitative Proteomics Using Isobaric Chemical Tagging and HCD",
journal = "Current Proteomics",
volume = "8",
number = "1",
year = "2011-04-01T00:00:00",
abstract = "Multiplexed stable isotope reagents such as iTRAQ and Tandem Mass Tag (TMT) designed for MS/MS-based quantitation of peptides rely on accurate and robust detection of low mass fragments for peptide precursor ions. In the past, such analyses depended upon mass spectrometers capable of producing the so-called "triple-quadrupole-like" fragmentation including triple quadrupole mass spectrometers (TQMS) and quadrupole time-of-flight (Q-TOF) instruments. The "one-third rule" on an ion trap (IT) instrument precluded the use of these reagents on this widely available instrument platform until the invention of Pulsed Q Dissociation (PQD), which in itself manifests problems in generating sufficient reporter ion intensities for accurate quantitation. The introduction of high energy collisional-activated dissociation (HCD) on LTQ-Orbitrap XL and LTQ-Orbitrap Velos platforms has opened up great opportunities for accurate quantitative analysis of proteins and their post-translational modifications (PTMs) using chemical tagging by generating "triple- quadrupole-like" fragmentation mainly in the low mass range in MS/MS mode. ",
pages = "31-38",
url = "http://www.ingentaconnect.com/content/ben/cp/2011/00000008/00000001/art00004",
doi = "doi:10.2174/157016411794697381",
keyword = "Phosphopeptides, TMT, high energy collisional-activated dissociation, LTQ-Orbitrap, ICAT, iTRAQ, Mass Spectrometry, Isobaric Labeling, MRM-MS, PTMs, MAlDi-TOF/TOF, Proteolysis"


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National Park Foundation
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A historic plantation originally built as a monument to George Washington overlooking the nation's capital, a site that later was home to Confederate Gen. Robert E. Lee and 63 slaves, will be restored to its historical appearance after a $12.3 million gift announced Thursday.
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a term meaning perfectly high on marijuana.
guy: want another toke mick.
mick: no thanks brew I am nicely toasted.
mick: no thanks brew I am nicely toasted.
by george January 20, 2005
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Castaway's favourite
Noël Coward
I'll Follow My Secret Heart
Artist: Yvonne Printemps
Presented byKirsty Young
Politician - Conservative, Campaigner
The castaway in this week's Desert Island Discs rejoices in the title of the Baroness Trumpington of Sandwich in the County of Kent.
A tireless campaigner on myriad issues, she brings to her work a commodity which is often in short supply in political life - a healthy sense of humour. Among other things, she'll be talking to Sue Lawley about her career, during which she has risen from being Mayor of Cambridge to Under-Secretary of State at the Ministry of Agriculture, Fisheries and Food - all without taking a single exam.
[Taken from the original programme material for this archive edition of Desert Island Discs]
Castaway's favourite
I'll Follow My Secret Heart
Artist: Yvonne Printemps
Cheek To Cheek
Chattanooga Choo Choo
La Vie En Rose
How About You?
Once In Royal David's City
Trio (from La traviata)
Soloist: Luciano Pavarotti, Joan Sutherland Orchestra: The Manuguerra & National Philharmonic
Soloist: Al Martino
Luxury item
Search the whole archive by typing into the box below. To find out who has picked particular music, books or luxuries on the programme use the buttons to refine your search.
This site contains archive material. To comment or bring something to our attention, please get in touch.
BBC © 2014 The BBC is not responsible for the content of external sites. Read more.
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Custom Recipes for
Quick and Yummy Hummus
Choose from dozens of top-rated roast turkey recipes, from stuffed to deep-fried.
We're counting down from now until Thanksgiving with a great pie every day. Join the fun.
Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $5!
See how easy it is to make your own hummus in a blender.
Two classic Greek recipes come together for an easy appetizer or main dish.
A creamy hummus with a little cayenne kick.
Read our allrecipes.com blog


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Shortly after WWE released their storyline update on Triple H's condition, several WWE talents posted reactions on Twitter.
Cody Rhodes ?@CodyRhodesWWE
HHH would be just fine not getting paid long as he still was able to walk down the ramp…I feel the same, so I can't imagine hanging it up.
Santino Marella ?@milanmiracle
I'm concern for HHH, back stage he looked . . . its hard to put in words but there seemed to be no wind in his sails, if that make sense
R-Truth ?@RonKillings
Big win for the tag team champs,,but I'm worried about HHH,,he's really banged up bad,,not to mention a broken arm..
TheMarkHenry ?@TheMarkHenry
Triple h and Brock was very good I expected such a match.H is long from done gladiators die in the ring.That man is not dead by a long shot.
Vickie Guerrero ?@ExcuseMeWWE
Triple H is built of steel, he will recover and face Brock once again!
Chris Jericho ?@IAmJericho
#SummerSlam was amazing! Great match w @HEELZiggler and I proved my point! And if that was HHH last stand…what a way to go out! #truewarrior
Natalya ?@NatbyNature
Can't help but wonder what is going to happen to HHH after his loss to Brock at SummerSlam. Maybe it's his last match as it was so intense.
The Hottest WWE news, photos and videos delivered to your inbox in one convenient newsletter. Sign up now and give it a try!
|WWE Survivor Series Report - 11/23/14
|WWE RAW Report - 11/24/14
|Sting Makes His WWE TV Debut, Possible Match Against Triple H?, Update on The Authority
|Backstage News on Sting vs. Triple H or The Undertaker, Speculation on Sting's WWE Future
|Backstage News on TNA's Talks with Spike, What Josh Mathews Is Working On, TNA Live Events


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Volume 32, number 4
Winter Solstice 2012
Greatest Hits: The Year in Pictures
Download this issue as a PDF
(Planetary Society members only)
6 The Bradbury Imperative: Andrew Chaikin reflects on why we must explore.
8 Where We Stand: Politics and budgets and waiting, with Casey Dreier.
9 COVER STORY The Year in Pictures: Emily Lakdawalla shares her favorite images from the past year.
Planetary Society Kids: Why is Mars colder than Earth?
16 Vacuuming Planets and Targeting Asteroids: Bruce Betts highlights two projects that Members support.
18 Infinite Visions: We asked some big questions, and Members answered.
2 Planetary Radio Mat Kaplan celebrates a remarkable milestone.
4 Your Place in Space Bill Nye makes Members' voices heard in Washington and welcomes Endeavour.
20 Snapshots from Space Phoenix gets its laugh on…
21 What's Up? Planets and the Geminids.
22 Volunteer Spotlight Geovanni Somoza calls all volunteers.
23 MySky Mars on Earth and a lunar eclipse.
LightSail - Flight by Light
Support LightSail!
In 2016, The Planetary Society's LightSail program will take the technology a step further.
Space in Images
Pretty pictures and
awe-inspiring science.
Join the New Millennium Committee
Let's invent the future together!


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Posts – Culture & History
The sounds of silence
The silence around me isn't a strict silence. It's an inclusive and forgiving silence, the kind that can accommodate the soft sighing of 1 000 lanterns, the gentle swishing of a calligraphy pen or the muted patter of bare feet. It's the kind of silence that moves with the cooing of the doves in the rafters, makes way for whispered prayers and embraces the sounds you make as you try to imitate it. It's a silence scented with incense, suffused with golden light and radiating calm warmth.more
Lovely landscapes in South Africa
South Africa is filled with rolling mountains, beautiful rivers and oceans, and stunning vistas which all contribute to a variety of lovely landscapes.more
Who goes there?
Churchill's South Africa, by South African journalist and historian Chris Schoeman, is a riveting account of Winston Churchill's time in South Africa and the story of how the young Winston Churchill became a hero to the British public.more
The people of South Africa
The Love South Africa Flickr group is constantly updated with fantastic images taken all over the country. Why not join us?more
Rivonia's Liliesleaf Farm 50 years on
Liliesleaf Farm in Johannesburg, where the ANC's top leadership was arrested in 1963, leading to the Rivonia Trial, is a must-visit for anyone interested in South Africa's turbulent political past.more
Eating out, township style
Share a slice of township culture by taking a tour of the Ekhaya Multi Arts Centre in KwaMashu township, which lies half an hour north of the coastal city of Durban (eThekwini). En route you'll get a feel for township life and experience the friendliness of the locals. End off with a true township-style meal of shisa nyama (meat cooked over an open fire), presented with a range of tasty accompaniments.more
The magic of a small community
Township tours in small cities and even villages can be quite enthralling, and much more relaxed and personal than the big bus experiences.more
Following in the footsteps of Dias
Mossel Bay started life in 1488 when Portuguese explorer Bartolomeu Dias sailed his sturdy, small caravel into the bay, and named it the Bay of St Blaise. Today a charming museum complex overlooking the lovely bay houses a replica of his ship plus other fascinating historical items.more
Hout Bay's East Fort: the world's oldest working original gun battery
Standing at the lovingly restored East Fort, high above Chapman's Peak Drive and Hout Bay in Cape Town, one wonders what it must have been like to be a soldier manning this globally unique redoubt in the late 1700s.more
The Tale of Fearless Fred
When you're finally on your Great Richtersveld Adventure, spare a thought for one Fred Cornell as you drive east along the Orange (Gariep) River.more


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Trip of a Lifetime
Known as the land of a thousand islands, beaches in Croatia are just as gorgeous as their more famous Italian counterparts. Soak up some rays on Hvar Island, stroll the streets of Old Town in seaside city ...Go to Destination
Konoba Batelina
No matter what you've been doing all day, hit up this restaurant for some melt-in-your-mouth truffle dishes. "Konoba" is Croatian for tavern, and you'll have to get directions from a local because this place doesn't have a sign.
Čimulje 25, 52100 Pula, Croatia
Nautika Restaurant
Chef Mario Bunda customizes a menu for you at the No. 1 restaurant in Dubrovnik, with dishes like fresh cream of scampi soup with black truffles and the catch of the day. Enjoy the incredible view of Old Town and the sea while you dine.
Brsalje no. 3, 20000 Dubrovnik, Croatia
The Wine Vault
Croatian master chef Tom Gretic specializes in French-Mediterranean cuisine. The restaurant, located in Hotel Monte Mulini, offers a variety of tasty dishes, including pheasant for 2 glazed with beurre noisette and topped with cold port wine sauce.
A. Smareglia bb, 52210 Rovinj, Croatia
More Croatia Travel Guides
No Reservations: No Reservations in the Croatian Coast
Get a complete list of the things that Tony Bourdain did while visiting the Croatian Coast.
Get the name and address for all the activities Dhani Jones enjoyed while in Croatia.
Other Croatia Travel Guides
Get the name and address for all the ...
More Travel Inspirations
GAC America's Amusement Parks
Buckle up and take a tour of the most thrilling amusement parks in America.
3-Ingredient Apps for Thanksgiving
Try Food.com's quick and easy apps for a stress free turkey day.
Food Network's Top Turkey Day Tips
Plan Your Menu with easy, how-to videos from Bobby, Sunny and more.


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realmagick.com The shrine of knowledge.
Hobo Spider Notes
A selection of articles related to hobo spider notes.
Original articles from our library related to the Hobo Spider Notes. See Table of Contents for further available material (downloadable resources) on Hobo Spider Notes.
- Spider: Grandmother of Creation
- At the dawn of summer, in the warmth of springtime, Spider peeks her head out and begins again to spin her tale. Her tale, like her web is spiral, each year bringing greater more elaborate worlds and possibilities into manifestation. Her story, her web is the...
Symbology >> Animals
- The Legend of the Dreamcatcher
- Long ago when the world was young, an old Lakota spiritual leader was on a high mountain and had a vision. In his vision, Iktomi, the great trickster and teacher of wisdom, appeared in the form of a spider. Iktomi spoke to him in a sacred language. As he...
Religions >> Native American, Shamanism
- Moon Gardening
- There is nothing more beautiful at night than looking up at the Moon and looking down at its audience. A symphony of beautiful flowers that stand at attention, when the night comes upon us! Whether you would like an Herb Garden, a Medicine Wheel Garden, or...
Earth Mysteries >> Herbalism
- Astral Beings and Wildlife
- The astral dimension contains a wide variety of what could be called non-physical subtle energy life-forms; or as Carlos Castenada so aptly calls them: inorganic beings. Some of these have a positive nature (nice) and some seem have a negative nature (not so...
Parapsychology >> Astral Projection
- Religious Tolerance In Springfield and the Greenleaf Coven
- Religious intolerance is alive and well in Springfield Missouri. The question is, to what degree, and in the terminology of "The Burning Times", how high are the flames? In 1999, the court case of Jean Webb vs. The City of Republic was a headliner...
Paganism & Wicca >> True Stories
- Synaesthesia: The Crossing of the Senses
- "We interpret one sense by another." William Hazlitt "Although medicine has known about synaesthesia for three centuries, it keeps forgetting that it knows. Richard Cytowic, in "Synaesthesia: Phenomenology and Neuropsychology a Review of...
Modern Science >> Synesthesia
- Who Were the Celts?
- The Celts were a group of people that occupied lands stretching from the British Isles to Galatia. The Celts had many dealings with other cultures that bordered the lands occupied by these people, and even though there is no written record of the Celts...
History & Anthropology >> Celtic & Irish
Hobo Spider Notes is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Hobo Spider Notes books and related discussion.
Suggested Pdf Resources
- How to Identify (and misidentify) the hobo spider
- the hobo spider because it has been blamed as the cause of dermatologic wounds. We offer may not be able to identify hobo spiders and may have to settle for determining that your spider is .. spider.
- pep.wsu.edu
- Notes: Hobo Spiders, listed in the Refer- ences section. One spider frequently found indoors is the common house spider, Achaeara- nea tepidariorum (Fig.
- schoolipm.tamu.edu
- Hobo Spiders
- Published by Utah State University Extension and Utah Plant Pest Diagnostic Laboratory. Fig. 1.
- extension.usu.edu
- Hobo or Not a Hobo-That is The Question... A Photographic Key to
- the main purpose of the key is to identify the hobo spider.
- extension.usu.edu
- Distribution of the Medically-implicated Hobo Spider (Araneae
- The hobo spider is considered to be medically important; T.
- www.geog.ubc.ca
Suggested Web Resources
- Brown recluse spider - Wikipedia, the free encyclopedia
- en.wikipedia.org
- Hobo spider - Wikipedia, the free encyclopedia
- Notes. ^ a b [1] Centers for Disease Control and Prevention (CDC).
- en.wikipedia.org
- Hobo Spider Management Guidelines--UC IPM
- UC home and landscape guidelines for control of Hobo Spider.
- www.ipm.ucdavis.edu
- ANRCatalog - Hobo Spider: Pest Notes for Home and Landscape
- anrcatalog.ucdavis.edu
- Spider Management Guidelines--UC IPM
- See Pest Notes: Hobo Spiders, listed in the References section.
- www.ipm.ucdavis.edu
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
Hobo Spider Notes Topics
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text:
The win32-event library provides an interface to Windows event objects. An event object is a synchronization object whose state can be explicitly set to a signaled state. Event objects are useful in sending a signal to a thread indicating that a particular event has occurred.
gem 'win32-event', '~> 0.5.1'
gem install win32-event -v 0.5.1


text:
It's highly likely that there is a limitation on how many synchronization objects - semaphores, events, critical sections - can one process and all processes on a given machine use. What exactly is this limitation?
For windows, the per-process limit on kernel handles(semaphores, events,mutex) is
From MSDN:
It depends on the quota that is available for the process. I think in XP it is set to 10000 per process, but it can grow. I am not sure what the upper limit is.
Just checked it again, the 10000 limit is for the GDI handles and not for Kernel objects.


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I highly recommend not staying at this hotel is you plan on using your credit card to pay for your stay. The only time I used my credit card during my stay in France was at the Stim'Otel and a couple of weeks after I got home I found out that my card had been compromised. There was no one... More
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Hotels.com, Expedia, Travelocity, Priceline, TripOnline SA, Odigeo and Tingo so you can book your Stim'Otel reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


text:
Dubai motorcycle insurance for non-resisdent
Further to this thread
I am trying to find motorcycle insurance (third party fire and theft) for the 3 or 4 weeks I will be here in Dubai but as I am not a resisdent Axa Insurance say they can not deal with me.
Can anyone recommend somewhere to go?
paul - PRExpressions
|All times are GMT +1. The time now is 04:50.


text:
n., having only Bono or Sonny Bono as exclusive sexual partners
"I wish I was Cher when she was bonogomous"
"I don't believe in bonogomy"
"I don't believe in bonogomy"
by roger the fabricator February 10, 2004
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November 24, 2014
CHARLESTON, W.Va. (WSAZ) -- The domestic violence petition in the case against Kanawha County's Prosecuting Attorney Mark Plants was extended through mid-September.
According to the document, the agreement which allows for increased and unsupervised visits with his children, will run through September 17th, 2014.
A temporary order went into place back in March. Plants spanked his son using a belt. The action, which Plants said was agreed upon by he and his ex-wife, left bruises on his son.
A domestic violence petition was issued against Plants to protect his ex-wife and their two children. A charge of domestic battery was filed against Plants. Plants was also later charged with violating the domestic violence petition.
The new order states "by issuing a final protective order at this time, the Court finds that this matter can move forward in a way that will allow Mark Plants to have increased unsupervised contact with his children, but will allow meaningful protection from physical and emotional abuse for the children and their mother. At this point, a more permanent resolution/solution would be more appropriately be addressed in the parties underlying divorce/parenting case."
The order also states that Plants should and will continue with counseling.
As far as the charges against him, Plants has entered into a pre-trial diversion program. If he meets certain guidelines within the next year the charges against him will be dropped. A hearing on that matter is set for June 24th, 2014.
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How do I change the size of my HTML site?
One of the features of a Wix site is that the height of the site's pages does not have a predetermined size. Your pages will adjust their height dynamically according to the content that you add to them. If you add more text or elements, your pages will become longer in order to accommodate them.
To make your page longer, click the element located at the bottom of your page (or any element that you'd like to move downward) and drag it down using the Drag Handle.
To shorten your page, click the element located at the bottom of your page, and resize it using the Stretch Handle or drag it upwards using the Drag Handle.
Currently, the width of your site is fixed at 980px. This size was chosen in order to accommodate the largest number of internet users that will be visiting your site. This is common for the new generation of sites, as it ensures compatibility with the many different smart devices being used today (i.e., iPads or tablets).
Check out our video on how to use the Wix Gridlines to optimize your site's layout:
Recent Discussions
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Ticket by millaeastwood4 | 2 days ago | 1 Replieshi there, i need some help making my homepage fit all on one screen so you don't have to scroll around, so when it come up it should it fit on one page.......
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Kate Bosworth's Hair Transformation
From braids to bobs, see all of the actress' memorable looks, right here.
Kate Bosworth's Many Hair Looks
From plaited updos to stark-straight bobs, we've gathered up our all-time favorite hair moments from Kate Bosworth. Get your fingers ready, these are pin-worthy!
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Summer/Fall 2014
Denver, Colorado
The University of Denver Sturm College of Law is exceptionally well represented in Denver and the metro area: There's hardly a law firm or corporate agency that doesn't have a Denver Law grad among its ranks.
And in many offices, DU is the No. 1 alma mater. On average, about 200 Denver Law grads take positions where JDs are either required or preferred, more than 85 percent of those in metro Denver alone. One school administrator could be forgiven a recent burst of enthusiasm, saying "We own this town!" It's much the same throughout the Front Range and the Mountain West.
More About Dan Reilly and Randolph Robinson
Reilly Pozner LLP serves clients nationwide and is engaged in complex commercial and intellectual property litigation, class actions, civil and criminal litigation, mass torts, personal injury and appellate law.


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Lafayette has 6 schools. Some of the best schools in Lafayette are Macon County Junior High School with a GreatSchools rating of 6/10 and a parent rating of 3/5 stars, and Lafayette Elementary School with a GreatSchools rating of 5/10. The average GreatSchools rating for Lafayette public schools is 4/10, with an average student/teacher ratio of 27:1.
School data provided by National Center for Education Statistics, Maponics, and GreatSchools. Intended for reference only. GreatSchools Ratings compare a schools test performance to statewide results. To verify enrollment eligibility, contact the school or district directly.
Property is in demand due to reduced inventory, as there are more potential buyers than sellers. Bidding wars with other buyers are possible, and listings begin to sell at greater than the asking price.
Not enough data to determine market type. Consult a local REALTOR® for up-to-date market summaries
Trend data coming soon.
Trend data coming soon.
|For Sale: 99
|New: 8
|Recently Sold: 92
|Reduced: 34
|Average Home Price
|Average Sold Price
|Property Records: 6,000
|Foreclosed: N/A
The average home price in Lafayette is $126,295, which is 41.3% lower than the average sold price in Lafayette ($89,406) . The average home price per square foot in Lafayette is $71 and about 2% of all homes in Lafayette sold in the last 6 months. For Lafayette home values, real estate prices, and city market trends, research the 6,000 property records or search our 92 recently sold or 99 homes for sale listings. The listings and properties in Lafayette are only a part of the 2,649,271 properties and 49,519 homes for sale in Tennessee. Because of this, the average home price and average home value of Lafayette also influence the average home price $214,311 and average sale price $189,682 of Tennessee. Listing counts, Lafayette home prices and home values in Lafayette are sourced daily from listing and property data on realtor.com®, which is the most up-to-date and accurate aggregation of real estate listings in the industry and includes approximately 800 regional MLSs and is the official website of the National Association of Realtors®.
|Median Age
|Median Household Income


text:
Where Do Animals Live?
Where do animals live? All living things need homes. Help these animals get back home by following the maze. This is a fun and easy way to introduce kids to animal habitats and shelters, a big part of life science learning for first graders!
Topics: First Grade, Life Science
Updated on Feb 20, 2014
This Weeks Deals
FREE Shipping on Orders over $50


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AD Tag – GNN
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Interview: Jamie Madrox (Horrorcore Rap Group Twiztid)
November 27th, 2014
Interviewed by: Rio
Interview: David and Daniela Tully (Writers for Dario Argento's The Sandman)
November 27th, 2014
Interviewed by: Dave Gammon
Interview: Ian Fetterman - Pumpkin Carver Extraordinaire
November 24th, 2014
Interviewed by: Horrornews.net
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Book Review: Axes of Evil - Edited by Alex S. Johnson
November 22nd, 2014
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Book Review: Equilibrium Overturned - Authors Anthony Rivera and Sharon Lawson
November 13th, 2014
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Category: Book Reviews
Film Review: Manson, My name is Evil (2009)
SYNOPSIS: Perry, a sheltered chemical engineer, falls in love with Leslie, a former homecoming princess, when he becomes a jury member at her hippie death cult murder trial REVIEW: "Manson, my name is Evil" is a curious title as when the end credits rolled by they listed the film as "Leslie, My name is Evil". I say this because, this actually is more inline with what the story is about. Sure it's rehashed alot of … Continue reading
Manson, My Name is Evil: October 12, 2010
The newest Manson flick arrives from Lionsgate on October 12, 2010. Manson, My Name is Evil, which stars Kristen Hager, Gregory Smith, and Ryan Robbins, follows Leslie (Hager), a former cheerleader and follower of Manson. During her murder trial, one of the jury members, Perry, a sheltered chemical engineer, finds himself falling in love with the dangerous woman charged. I am sick of Manson, yes he is evil but if you really think about it … Continue reading


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Deportivo La Coruna have completed the signing of Barcelona youngster Rodri, who joins the Galicians on a four-year deal.
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The 21-year-old, who plays at centre back, arrives on a free transfer having been released from his contract by Barca.
However, the Catalans have inserted a buy-back option into the transfer meaning they will have the opportunity to buy him at the end of the next two seasons should he impress at Depor.
A product of Barca's youth system, Rodri has been on the fringe of the first-team picture for the past couple years but has failed to claim a starting berth.
As a result he has now opted for a fresh challenge and is excited by the prospect of his move to The Riazor.
"It's a very important jump because there was no place for me at Barcelona and I come to Deportivo with a lot of excitement and desire and with the intention of impressing," he stated.
Meanwhile, Deportivo are looking to wrap up the signing of Liverpool's Antonio Barragan next week with president Augusto Cesar Lendoiro insisting the agreement between the two clubs is total.
Lendoiro is also hopeful of landing Racing Santander goalkeeper Dudu Awat, but was quick to play down talk of a move for Real Madrid's Alvaro Arbeloa insisting "there is nothing to report".


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This threat of danger didn't stop Romedio Viola, a former special agent with U.S. Immigration and Customs Enforcement (ICE), from investigating the cartel and bringing its leadership to justice. His efforts were detailed in Jeffrey Robinson's recently released book, "The Takedown."
Viola's actions represent the work of all ICE Homeland Security Investigations (HSI) special agents. As the largest investigative agency in the U.S. Department of Homeland Security, ICE HSI agents conduct bulk cash, fraud and drug trafficking investigations every day.
Today, ICE HSI's presence across the country is unmatched. Agents serve on a multitude of task forces to combat drug smuggling. To date, in fiscal year 2011, ICE HSI agents seized nearly two million pounds of drugs and more than five million dollars in illicit funds. They have also detected and shut down weaknesses in the U.S. financial trade and transportation sectors, which serve as smuggling routes for criminal organizations like the Norte Valley Cartel.
"As a special agent, they tell you to go chase the bad guys. So you get out there and you pull together with your fellow agents to get the job done. I was proud to be a part of ICE; I still am," said Viola.
In "The Takedown," Viola was described as a man driven to bring down criminals. That description is fitting for not just him, but for all of the men and women of ICE who work tirelessly to bring drug trafficking organizations to justice.
Learn more about ICE HSI's role in narcotics enforcement.


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套件: wesnoth-ttb (1:1.6.5-1build1) [universe]
wesnoth-ttb 的相關超連結
Ubuntu 的資源:
下載原始碼套件 wesnoth:
Please consider filing a bug or asking a question via Launchpad before contacting the maintainer directly.
Original Maintainers (usually from Debian):
- Debian Games Team (郵件存檔)
- Isaac Clerencia
- Cyril Bouthors
- Gerfried Fuchs
It should generally not be necessary for users to contact the original maintainer.
- 主頁 [wesnoth.org]
"A Tale of Two Brothers" official campaign for Wesnoth
This package contains the "A Tale of Two Brothers" campaign for Wesnoth: "An evil mage is threatening the local village and its inhabitants. When their leader Bjarn sends for aid from his brother Arne, he is victorious, but Bjarn himself is kidnapped. Can you rescue him?" (Novice level, 4 scenarios; the 'Hard' version may challenge more experienced players.)
Battle for control of villages, using variety of units which have advantages and disadvantages in different types of terrains and against different types of attacks. Units gain experience and advance levels, and are carried over from one scenario to the next in a campaign.
其他與 wesnoth-ttb 有關的套件
- dep: wesnoth-core (<< 1:1.7)
- fantasy turn-based strategy game
- dep: wesnoth-core (>= 1:1.6)


text:
LNP party announcement
LNP party announcement
Source: ABC News | Duration: 10min
Alex McClintock
In many ways The Mule is a typical Aussie production, but the innovative way it's being distributed could be a game changer for the local film industry.
by political reporter Melissa Clarke
Opera companies are concerned their funding could be cut after a review by the Federal Government.
There is much to dislike about organised party politics, but with six members of the Senate crossbench now voting whichever way they please, we will soon discover that structure and discipline has its perks.
A man with an amazing sinkhole on his property cannot share it with tourists because of insurance concerns.


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Integrating Women of the Bible with Women Today 22 November 2014 - Job's Wife
in Religion
Integrating Women of the Bible with Women Today 22 November 2014 - Job's Wife
We women today need to understand what God's plan is for us in today's society. God is NOT difficult. We need to understand the women of the Bible, their trials and the understanding of the Virtuous Woman in Proverbs. God is real and we are his tangible testimonies. Let's prepare ourselves to live according to the scriptures of God's Holy Word.
Host-Minister Rhonda Bello
Co-Host-Pastor Bamidele Bello, Senior Pastor and Founder of Holy Mountain International Ministries
Minister Rhonda Salazar
in Religion
Minister Rhonda Salazar of Gainesville Texas. Sharing the good news of Jesus and telling her testimony. Minister Rhonda loves children. The words of Minister Rhonda: Trapped & Lost in Darkness & Pain ...Searching ..Yearning...LONGING with every fiber of my being to be Loved With a Real & LASTING LOVE...
Chatting with Rhonda Laurel
in Books
Rhonda Laurel is a contemporary interracial/multicultural romance writer whose two great loves are writing and landscape photography. She uses both as a vehicle to convey the complexity of the human spirit and the beauty of the world around her. Ebb Tide, For the Love of the Game and Masquerade were released in 2012. Shutter, Memories of You, Star Crossed, MVP and California Bored and Tourism in 2013.
The print anthology, The Rhonda Laurel Collection, featuring Ebb Tide, For the Love of the Game and Shutter released June 2013.
The print anthology, The Blake Boys Collection, featuring For the Love of the Game, MVP and The Blake Legacy released February 2014.
Rhonda Liebig Shares The 14 Day Flat Diabetic Belly Diet
in Women
Rhonda Liebig is a return guest to E Factor Radio. She brings a freshness and a deep seeded desire to improve the lives of her clients and those she interacts with in her various media events.
For anyone wishing to live a more vibrant, beautiful, and healthy life to reduce the risks and ravages, join us for this very timely event!
Integrating Women of the Bible with Women Today 8 November 2014 - Ruth
in Religion
Integrating Women of the Bible with Women Today 8 November 2014 - Ruth
We women today need to understand what God's plan is for us in today's society. God is NOT difficult. We need to understand the women of the Bible, their trials and the understanding of the Virtuous Woman in Proverbs. God is real and we are his tangible testimonies. Let's prepare ourselves to live according to the scriptures of God's Holy Word.
Hey, Help Me Rhonda
in Entrepreneur
Today we will be discussing product launches. I will be giving tips for a successful launch. If you are planning a product or program launch, you will want to tune in to days show.
Where In The Whirl - Rhonda Denise Johnson
in Radio
Interview with Rhonda about her newest book.
Getting To Know Authors Farrah Rochon and Jennifer Lohmann
in Books
native of south Louisiana, Farrah Rochon officially began her writing career while waiting in between classes in the student lounge at Xavier University of Louisiana. After earning her Bachelors of Science degree and a Masters of Arts from Southeastern Louisiana University, Farrah decided to pursue her lifelong dream of becoming a published novelist. She was named Shades of Romance Magazine's Best New Author of 2007. Her debut novel garnered rave reviews, earning Farrah several SORMAG Readers' Choice Awards.
When she is not writing in her favorite coffee shop, Farrah spends most of her time reading her favorite romance novels. An admitted sports fanatic, Farrah feeds her addiction to football by watching New Orleans Saints games on Sunday afternoons.
Jennifer Lohmann is a Rocky Mountain girl at heart, having grown up in southern Idaho and Salt Lake City. She's always been a reader--of romance novels, mysteries, nonfiction, cereal boxes, etc. If it had words, she tried to read it.
Jennifer had been writing, on and off, for many years when she won the Romance Writers of America Librarian of the Year award in 2010. Being at the RWA conference reminded her how much she loved writing and she became more serious about it. As part of Harlequin's "So You Think You Can Write" Contest, she was offered a contract on her first book in 2012. She spends her days surrounded by people, talking about books, and creating community. Her nights (and early mornings) are spent imagining the loves of other people and writing their stories.
She lives in the Southeast with a dog, five chickens, and four cats.
Off The Grid In Black Towns - Professor Rhonda Ragsdale
in Real Estate
Today on "It's My House" we shall discuss one of the most important success strategies within ANY community and in life and that is knowing HOW to "get off the grid". Most of us live in a world of debt. We have car payments (to a bank), we are in partnership with banks to live in our homes. Many of us live pay check to paycheck and we are in debt. How can we get out of the rat race ? The answer is simple.
Get Off The Grid !
Former slaves with little or no cash, no bank financing, no government aid, and no sense of entitlment found succes by "getting off the grid" and building their own townships.
Today Professor Rhonda Ragsdale will gives us a much needed history lesson and how we can apply those "off the grid" principals so that we can have success today.
Black Towns Business Model & Municipal Literacy with Professor Rhonda Ragsdale
in Real Estate
Today on "It's My House" we shall discuss "Municipal Literacy" and what it takes to become "municipal literate". We shall the Black Towns Business Model to demonstrate Municipal Literacy with Professor Rhonda Ragsdale.
How was it that the former slaves who pioneered the Black Towns Social Movement were able to transform themselves into land barons and real estate moguls and build towns WITHIOUT any formal education, bank financing, or government aid ?????
We shall take a look at American Beach, Florida, Abraham Lincoln Lewis, and Boley, Oklahoma.
Professor Rhonda Ragsdale of Black Towns Radio will clue us in to their success strategies and help us to become municipal literate.
Rhonda Johnson and Memoirs of An Addict
in Books
Born and raised in the Nation's Capitol, Washington, DC, M/R {Memoirs Rhonda} Johnson is the author of Memoirs of An Addict: Fact or Fiction.
Inspired by her story as someone living with co-occurring disorders, Rhonda offers insight from a dynamic perspective, drawing from her personal experiences, clinical education, and professional work background. She feels compelled and empowered to be an advocate of change by promoting Hope that recovery is a Process and it is Possible.
A graduate from the Dept. of Behavioral Health's Co-Occurring Clinical Competency Course, and the Office of Consumer and Family Affairs Certified Peer Specialist Certification Program, both in her hometown of Washington, DC, she has become a leader amongst her peers by sharing her challenges and experiences within the recovery of mental health and addiction's communities through motivational speaking and interactive workshop presentations.
M/R Johnson is the creator of several social networking groups that she facilitates on LinkedIn, {ATT} Addiction the Truth, and Certified Peer Specialists {United} on Facebook where members can engage or start therapeutic discussions of interest by demonstrating leadership and share education to unite in knowledge.
M/R Johnson believes her time has come, and that no matter what challenges a person encounters in this road to life, "All things are possible with FAITH in God!"
Midweek Business with Rhonda Nails and Lea Mcleod
in Lifestyle
Our special guest today with join us in conversation as we talk about "The Game". She's been on the show before, she is a friend of the show. Ms. Tameka Royster helped us last time with the 'Decision to follow your vision'.
Rhonda Nails, The Success Instigator is coming to share more from the Organized Obstacles Anthology. Today her guest will be: Organized Obstacles Contributor Richelle Shaw
A chat with Organized Obstacles contributor and 8 Figure Consultant, Richelle Shaw
Join Lea Mcleod of www.leamcleod.com as she shares more about beefing up your LinkedIn profile.
- ...
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Arrow, cat shot by dozens of pellets, adopted
Arrow, an Arlington cat shot by dozens of BB pellets earlier this year, now has a new home.
Ben's Chili Bowl opens in Arlington
Ben's Chili Bowl opened its first location in Virginia on Thursday with a ribbon-cutting ceremony (and Bill Cosby) in Arlington.
Water main break causes Arlington traffic jam
Several lanes closed, drivers rerouted.
Jennifer Lawson, 39, dies after truck accident in Arlington
The horrifying pictures of the car tell a lot about what happened here in Arlington. The back door of the minivan has been torn off, with the child car seat in the back still in place.
Route 1 bus lanes would ease congestion
Four-and-a-half miles of new bus-only lanes could be added to Route 1, costing $20 million and adding seven new transit stops, all designed to ease congestion in the area.
Police use stun gun on school cafeteria worker after gun threat
An Arlington cafeteria worker is in custody after allegedly pulling a knife on her vice principal Wednesday morning.
Gunston Park Bubble damaged by heavy snow
The Gunston Park Bubble, a beloved recreational center which houses indoor soccer games for all of Arlington County, was damaged by heavy snow.
Arlington BB&T branch robbed at gunpoint
Police are on the lookout for two men who robbed the BB&T on South Quincy Street in Arlington.
American Airlines 9/11 flight attendant wings on display at airline museum
A set of flight attendant's wings and flight attendants union pin retrieved from the thousands of tons of debris created when an American Airlines jet flew into the Pentagon have been returned to the airline and are on display in its museum.
Hundreds brave freezing temps to remove wreaths at Arlington National Cemetery
Below freezing temperatures didn't stop hundreds of people from removing thousands of wreaths at Arlington National Cemetery Saturday morning. ABC7's Tommy McFly has the story.
Rosslyn fatal accident closes multiple intersections near Key Bridge
An accident early Friday morning killed a driver in Rosslyn and closed multiple major intersections while police investigate.
Working outdoors in snow necessary for many
If you don't think working outdoors in the snow is dangerous, just ask the driver of this bus trying to negotiate a turn on a snow-covered hill in Arlington.
DC Tattoo ExpoComment
Over 250 of the world's best tattoo artists will be in town this weekend.
Benjamin Andruss hits man with car while driving wrong way in Arlington
Authorities say that Benjamin Andruss Andruss hit four cars with his Mercedes Benz before hitting a 33-year-old Washington man.
Arlington swimming and fitness complex plans up in the air following pricey estimates
Arlington County officials are considering downsizing, delaying or scrapping plans for a planned indoor swimming and fitness complex.
Arlington County to get get new elementary school in 2015
The Arlington County School Board approved Thursday night the final designs for the school in Arlington's Williamsburg neighborhood, which is slated to open in September of 2015.
Arlington fire truck caught in sinkhole
A fire truck became the victim of a sinkhole in Arlington Friday morning.
Three alarm fire at Arlington apartment
Investigators say an apartment fire in Arlington caused $50,000 dollars' worth of damage.
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Only On 7
The ABC7 I-team investigates cop cruiser crashesCop Cruiser Crashes happen more often than you think in the Washington area. Are officers being held accountable? And should you be paying the price? The I-Team investigates TONIGHT on ABC7 News at 11 after "Castle."


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Navi Mumbai Municipal Transport - Wikipedia, the free ...
Navi Mumbai Municipal Transport (NMMT) is the transport wing of Navi Mumbai Municipal Corporation, which operates bus services in Navi Mumbai. NMMT buses …From:http://en.wikipedia.org/wiki/NMMT
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Category:Shiv Sena politicians - Wikipedia, the free ...
Pages in category "Shiv Sena politicians" The following 76 pages are in this category, out of 76 total. This list may not reflect recent changes . ...From:http://en.wikipedia.org/wiki/Category:Shiv_Sena_politicians
Mumbai North Central (Lok Sabha constituency) - Wikipedia ...
Mumbai North Central Lok Sabha constituency is a Lok Sabha (parliamentary) constituency of Maharashtra state in western India. Contents 1 Assembly segments 2 …From:http://en.wikipedia.org/wiki/Mumbai_North_Central_(Lok_Sabha_constituency)
| Search Results | My Lord Ganesha
The Hindu god Ganesha is referred to by 108 names in mythology. On the occasion of Ganesh Chathurti, Nishad Pai Vaidya picks 11 cricketers who were named after the ...From:http://mylordganesha.com/?s=
India CEOs & Directors Detail - Scribd
India CEOs & Directors Detail - Free ebook download as Excel Spreadsheet (.xls), PDF File (.pdf), Text file (.txt) or read book online for free.From:http://https://www.scribd.com/doc/14060046/India-CEOs-Directors-Detail
Selling A Better Life - Forbes - Information for the World ...
Oct 24, 2012 · In the rough-and-tumble business of direct sales, Malaysia's Vijay Eswaran learns from mistakes and builds a movement.From:http://www.forbes.com/sites/donaldfrazier/2012/10/24/selling-a-better-life
108GAME - Play Free Online Games
Free Online Games at 108GAME.com. Awesome action games, puzzle games, adventure games, multiplayer games, skill games & best action games.From:http://www.108game.com/?_escaped_fragment_=&_escaped_fragment_=
Kyle name meaning - SheKnows
Yiddish Meaning: The name Kyle is a Yiddish baby name. In Yiddish the meaning of the name Kyle is: Victorious. American Meaning: The name Kyle is an American baby …From:http://www.sheknows.com/baby-names/name/kyle
List of Old Doordarshan TV shows and Serials – AbhiSays.com
The 80s was the era of Doordarshan with soaps like Hum Log, Buniyaad and comedy shows like Yeh Jo Hai Zindagi which made Doordarshan a household name.From:http://abhisays.com/india/list-of-old-doordarshan-tv-shows-and-serials.html


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Report Roundup
Demographic Changes
"The Rapid Growth and Changing Complexion of Suburban Public Schools"
Hispanic students have become more segregated in suburban public schools over the last decade, even while blacks and Asians have become slightly less isolated, according to a new study.
The Pew Hispanic Center found that the nation's suburbs added 3.4 million students from 1993 to 2007, representing two-thirds of the growth in public school enrollment. Virtually all the suburban growth—99 percent—came from the addition of Hispanic, black, and Asian students.
But while black and Asian students saw small gains in integration, Hispanic students were increasingly clustered at the same suburban schools. The study found their segregation was particularly evident not only in counties around Chicago, Poughkeepsie, N.Y., and in Prince George's County, Md., where their population is small compared with blacks' and whites', but also in areas with larger Hispanic concentrations, such as the Los Angeles, Miami, and San Diego metropolitan areas.
The researchers said the findings challenge the conventional assumption that growing minority populations will create an instant "melting pot" in suburban and other districts and raise questions about whether local school boards need to actively promote integration
The report says one factor in the growth of minority students in suburban areas has been the growing popularity of charter schools, some of which have special ethnic themes or offer bilingual courses that attract minority students.
Vol. 28, Issue 28, Page 5
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Is It OK to Hate Your Boyfriend's Ex?
Is It OK to Hate Your Boyfriend's Ex?
Ah, the ex factor. No matter what your situation, ex-girlfriends of your current flame are hard to ignore, and they can often put a damper on the new relationship. A recent article in the UK's Mirror gives explicit instructions on how to cope with your boyfriend's ex when they are still "friends." Since we all know that remaining friends with an ex can be a bad idea, it's no wonder that many new girlfriends need some encouraging words of wisdom.
The article suggests that the new girlfriend should avoid aggression, as it's a sign of jealousy, while other people think it's OK if the ex knows you're jealous of her. I happen to think that the ex "wins" in a sense if she gets the best of you, so my motto has always been to kill them with kindness. What about you? Even though deep down we often hate our boyfriends' exes, do you think it's OK to be forthcoming with those negative feelings, or do you think it's better to just bite your tongue?
- We love a dark wedding palette thanks to these stunning photos — 100 Layer Cake
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- The wedding-day survival checklist you need to print out — Style Me Pretty


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Great food at reasonable prices....not a large menu, but, what you can get is great. Very friendly staff also.
My husband and I have been eating lunch here ever since the placed opened. Their subs are great, especially the eggplant parmigiana. Everyone is friendly, the price is reasonable, and the place is always busy. We've never been disappointed.
This is one of our frequent stops. The men who own and operate Arthur Ave are always friendly. The service is prompt and the food is great. We like it so much that we ask for gift certificates from there for Christmas and have given gift certificates to others from there for Christmas.
I've been here in the past to order penne ala vodka several times which was the best I have had in awhile as compared to other places. The Gentleman behind the counter has excellent customer skills, he writes your order as exactly as you want it.No questions asked. I was last there a few weeks ago and ordered a steak...
If I could give 6 stars I would. We happened upon what we thought was a shopping center deli...how wrong we were! I had the Antipasto which was delicious. I then found out that they make the mozz on premise. The meats were fresh and the roasted red peppers just like the ones found on the real Arthur Avenue. My...
Their food is very very good. Like the Antipasto salad. They make a great Italian hero. Their bring home cheeses are good and store made salads. A great place to eat lunch only one flaw is the fact that they don't have a bathroom! Really who wants to eat lunch somewhere and be told you have to go into K...
What a delicious grouping of entrees from Arthur Ave Italian Deli! Eggplant Parm., Chicken Dianne, Chicken in a White Sauce and Baked Ziti. It was a delicious catered affair. Thank you for making our annual holiday get-together so enjoyable.
Fantastic subs, salads, pastas, Italian dishes, desserts, deli items, you'll think you're on Arther Ave., not in the Poconos! The owners are nice guys that give you great service.
I absolutely love Arthur Ave! I am a native NYer and this place makes me get my NY deli fix without the travel! The cold cuts are Boars Head, so I love that. The prosciutto is divine! I have eaten here for years and highly recommend any meal. The only downside to the location is the lack of bathrooms, but...
Been here for munch MANY times and ALWAYS HAPPY! Quality Italian heros and the Antipasto is Spot on!
Register now for free — and start getting automatic notification of new reviews, responding to traveler feedback, adding new photos to your listing and much more.


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The Coca-Cola Co. has introduced a mango limeade juice from Odwalla called "Haiti Hope," with profits to be used for reconstruction in the earthquake-shattered country. The drink was launched at a United Nations event, and profits also will be used to plant mango groves in Haiti, supplying local jobs.
View Full Article in:Miami Herald (free registration), The
Published in Brief:


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Nearly two-thirds of private companies surveyed are optimistic about the U.S. economy - Nearly half voice a willingness to assume new business risks in pursuit of growth - Over one-third expect to make major new capital expenditures over the next year
Meritus Hotels & Resorts announced the signing of a management agreement with Indonesian property developer PT. Bali Seminyak Sejahtera to operate a new-build resort in Seminyak, one of the most popular destinations on the island of Bali, Indonesia.
The 266-room property, created in collaboration with award-winning Italian architect firm Matteo Thun & Partners, has an exceptional lagoon location on its own island, with stunning views of St Marks Square and La Serenissima.
Hotels in Brisbane, Australia, achieved occupancy levels of 93.5 percent, an increase of 10.6 percent, during the week of the G20 Summit, which was held 15-16 November 2014, according to data from STR Global.
The breathtaking Himalayas offer both the backdrop and the inspiration for JW's first resort in India, the JW Marriott Mussoorie Walnut Grove Resort & Spa.
Both Milan and Prague achieved impressive year-on-year surges in gross operating profit per available room (GOPPAR) by 37.5% and 22.6% respectively, according to the latest data from HotStats.
Most popular articles shared on social networks by our readers this week


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Friday, July 8th, 2011
Belated. First for the Comores, here's Rikaef. They live in France (big Comores diaspora) and they're like four mini Lil' Waynes:
Wednesday, May 25th, 2011
The Very Best–a collaboration of Esau Mwamwaya and Radioclit–has a new mixtape. It came out a few weeks ago. It is still good for Africa Day. Download it here.
Monday, September 20th, 2010
Longtime readers of AIAC know that we love The Very Best, whose music, at least according to the MySpace, apparently falls under the categories "Melodramatic Popular Song / Showtunes / Tropical." Right. Whatever you want to call...
Wednesday, June 23rd, 2010
Thursday, May 6th, 2010
A bit late on this but Pitchfork.tv recently unveiled their latest series, Selector, in which they offer a rapper two different beats, one of which the rapper picks as a backing track for a freestyle....


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The Resource Finder has powerful filtering features — check out the tutorial to learn more.
Confessions of a Failed Young-Earth Creationist
I became such an expert in young-earth creationist theology and science that it turned into a wrecking ball for my faith.
Saturday Science Links: November 8, 2014
In this week's edition, learn about amphibious dinosaurs, frozen bison mummies, and hummingbird combat.
Soul, Strength and Mind: How BioLogos brought me out of hiding
Science is an honest and noble pursuit, evidence of human intellect and curiosity, and to turn away from these is to deny a very important part of who God created us to be in the first place.
Saturday Science Links: October 25, 2014
In science news this week, read about magical nose cells, 45,000 year old thigh bones, and the weirdest looking dinosaur ever.
God Decides, We Measure
The former chair of the Harvard University physics department muses on how faith gives meaning to his scientific work.
The Genesis Rock
The story of the Genesis Rock reminds us of how biblical and scientific accounts, despite their different purviews and purposes, remain inexorably linked in our understanding of origins.
Growing Up Evangelical: My Story of Making Peace With Evolution
My childhood in the evangelical church gave me the toolkit that led me to eventually accept the evidence for evolution, and marvel at the God who created it all.
Ch. 5-6: How the Categories Shape the Conversation
The words we use to talk about the Bible and science often predispose us towards unnecessary conflicts.
The Evolution of a Southern Baptist
Recent high-school graduate Jacob shares about his journey from young-earth creationism to evolutionary creationism, and how his faith was challenged and strengthened along the way.
The Tradition of Wisdom for Today: a Relational Theology of Science
If discussions of science and religion sometimes get bogged down in Genesis, perhaps that is because they have not made the preparatory journey through the rich material of the Wisdom books.
Origins News Round-up for September 30, 2014
Are black holes in trouble? Could life have come from space? What do we know about the religious lives of Indian scientists? Find the answers to these questions and more.
Series: Communication, Love, And Faith: A "Sayonara" from former BioLogos Web Editor Emily Ruppel (2 entries)
Origins News Roundup for September 17, 2014
Read about the death of Wolfhart Pannenberg, still debating creation and evolution, and a really big dinosaur discovery.
Origins News Roundup for September 3, 2014
This week's news features volcanoes, skeletons, and stars, as well as a thought-provoking new book from InterVarsity press.
Origins News Roundup for August 20, 2014
From science and religion blogs: quantum uncertainty and God, the remarkable fact that we have come to understand our place in the created order, and the role of theology in making wise choices about the use of technology.
How did God create the ingredients for life?
God could have created a fertile planet miraculously in an instant, but when we look carefully at the physical evidence, it appears that the earth has a longer history as part of the universe.
Series: BioLogos Basics (5 entries)
So what is BioLogos? Well it all began with a scientist and a book.
What about the Bible?
What we do learn from scripture is that there is only one Creator and that there's a clear distinction between God and the created world. And that we who are created in the image of God are able to investigate a creation that is remarkably tuned for our discovery.
Series: Excerpts from "Evolving: Evangelicals Reflect on Evolution" (13 entries)
We need to hear stories from others who have wrestled with evolution and Christian faith. What arguments made them change their views on science? How did they hold fast to their relationship with God? The essays in this series will eventually comprise a book, provisionally titled, "Evolving: Evangelicals Reflect on Evolution."


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Mofos B Sides amateur VIDEOS (34)
Our budd found this amateur girl showing off her body on the net, and offered her a gig with us. First, Rachael told us all about her nympho sex life, then she boned our buddy right there. She deepthroated his cock, then got fucked HARD from behind.
92 %
44012 views - 3 months ago
Alli, Ava - Mofos B Sides
Imagine meeting a legendary porn star while house-hunting with your girlfriend? Dude had the camera rolling as Ava Addams changed in her room, then that Milf took the couple in hand and guided them through filming their own amateur threesome porn.
96 %
110417 views - 3 months ago
An amateur couple's private session with a Milf sex therapist turned XXX-rated when they realized she was actually porn star Joslyn James. After Sasha learned to deepthroat, this horny pair sent in this tape of their dirty threesome.
94 %
49137 views - 3 months ago
Kylie was just chilling on vacation with her man when they bumped into porn star Summer Brielle at a cafe. Since Summer had a few hours to blow before her flight, she took the horny amateurs upstairs to show them how a real porn star fucks!
91 %
42452 views - 4 months ago
Dude was quick whipping out his camera to catch a horny-ass couple putting on a freaky sex show in the public bus. He filmed that amateur slut peeling her pants off and letting dude pound her pussy and even throw his dick deep in her tight asshole.
91 %
71674 views - 7 months ago
Pull the security tapes on the park and you'll see Alina Li getting double-teamed in her car. When she found out these two randos had thick cocks, she stuck her ass out the window so dude could fuck her so raw while she sucked off his friend.
Amateur couple having sex on a city bus without any concern for who's watching.
If slutty couples chillin' at home decide they wanna make some amateur porn and send it to us, we gonna say no? Check out this hottie getting banged hard by her BF. She uses her mouth, hands, and that fresh pussy to make her man cum fat loads of jizz...
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96424 views - 11 months ago
We heard the park every single night is full of real sluts who want to get pounded by rando cock. So we headed out with a camcorder, and stumbled on this whore Sienna Day. She was so thirsty for fucking, she sucked and fucked down these two guys.
Ariana Marie heard what dogging is and right away she felt fucking desperate to try it out. She went to the park one night and flashed a couple handsome guys until she'd found willing companions for a sneaky double-team right on the hood of the car.
The casting couch had a Latina hottie today. Cynthia came by the office to audition for some work in porn. Brandi was there to give this amateur slut some pointers. Cynthia didn't need any help getting comfortable, she was ready to perform right away...
Finally, some hot punk ass on the casting couch! Stacey came to audition for porn work, and was an instant fit. She fucked like a pro, and wanted more by the time the casting agent was done testing out her stripping, dicksucking, and fucking skills.