text:
Are you Hitoshi Nagatsuka?Claim your profile
Publications (228)338.27 Total impact
Article: Early initiation of endochondral ossification of mouse femur cultured in hydrogel with different mechanical stiffness.[Show abstract] [Hide abstract]
ABSTRACT: Mineralization is one of the most important processes in normal bone tissue development and in disease condition. Developing a novel and standardized in vitro model system that can readily monitor both cellular dynamics and mineralization is crucial for better understanding the bone tissue development and growth. Recent studies indicated that the mechanical environment is critical condition in mineralization. We hypothesized that hydrogel with different mechanical stiffness can provide a biomimetic mechanical environment that can modulate bone tissue growth and mineralization. A femur of mouse embryo (E16) was embedded in agarose hydrogel (2-60 kPa) and cultured in osteogenic medium for a week. Micro computed tomography (µCT) results revealed the enhanced mineralization was detected in femur head cultured in the gel condition, while no mineralization in the femur head cultured in control (floating culture) condition. The mineralized region was corresponding to the region of secondary ossification center. Both histological and quantitative analyses indicated that the mineralized region of femur head cultured in 10 kPa gel condition was the highest and the mineralized area was significantly larger than that cultured in 2, 40 and 60 kPa gel condition. Immunofluorescence results indicated that the enhanced mineralization caused by the higher chondrogenic differentiation at that region. This enhancement mainly relating to the mechanical forces not to the oxygen tension was also confirmed. Since this system enhances and shorten the mineralization procedure compared to the conventional 2D or 3D cell culture system, this hydrogel system would be one of the unique models for better understanding the mineralized tissue development.Tissue Engineering Part C Methods 11/2014; · 4.64 Impact Factor
Article: Does HMGB1 predict occult neck lymph node metastasis in early tongue carcinoma? A case-control study of 26 patients.[Show abstract] [Hide abstract]
ABSTRACT: Objective: This study examined whether the occurrence of late neck metastasis in early tongue squamous cell carcinoma can be predicted by evaluating HMGB1 (high mobility group box 1) expression in the primary lesion. Methods: A case-control study was conducted. The cases comprised 10 patients with late neck metastasis. The controls consisted of 16 patients without recurrence. All were examined immunohistochemically for HMGB1 protein expression. The odds ratio for late neck metastasis in relation to HMGB1 was estimated. Results: Results for HMGB1 were dichotomised into positive staining scores (score, 5-7) and negative scores (0-4). Six cases (60 per cent) and four controls (25 per cent) were HMGB1-positive. Although no significant result was seen, compared with HMGB1-negative patients the odds ratio for late neck metastasis in HMGB1-positive patients was 3.8 (95 per cent confidence interval, 0.6-26.5) after adjusting for other factors. Conclusion: In the present study, immunohistochemical study of HMGB1 in early tongue squamous cell carcinoma did not appear to be very useful for predicting occult neck metastasis. Further study is necessary to clarify the relationship between HMGB1 expression and late neck metastasis in early tongue squamous cell carcinoma.The Journal of laryngology and otology. 09/2014;
- [Show abstract] [Hide abstract]
ABSTRACT: Abstract Conclusion: In tongue squamous cell carcinoma (SCC), high levels of regulatory T-cell (Treg) infiltration in tumor nests are observed in the cases with poor prognosis. Objectives: The role of Tregs in head and neck cancers remains unclear. The aim of this study was to observe the distribution of Tregs in different stages of tongue SCC and estimate the effects on prognosis. Methods: Thirty-four cases with tongue SCC were examined immunohistochemically for CD4, CD8, and Forkhead box P3 (Foxp3). Immunoreactive cells were counted in cancer stroma and nest regions, and relationships between cell numbers and disease-free survival rates were analyzed. Results: In the 34 cases, univariate analysis for disease-free survival indicated high-level infiltration of Tregs (CD4(+)Foxp3+) into both cancer nests and stroma and presence of helper T (CD4(+)Foxp3-) cells in cancer stroma as potential predictors of significantly worse prognosis. In early-stage cases (stage I/II), high-level infiltration of Tregs in cancer nests correlated significantly with poor disease-free survival rate. Multivariate analysis for disease-free survival found no independent variables.Acta oto-laryngologica. 06/2014;
Article: Locally injected dexmedetomidine inhibits carrageenin-induced inflammatory responses in the injected region.[Show abstract] [Hide abstract]
ABSTRACT: Dexmedetomidine, a highly selective agonist of α2-adrenoceptors, is a commonly used sedative; however, a potent anti-inflammatory effect has also been found. In the present study we evaluated the inhibitory effect of locally injected dexmedetomidine on inflammatory responses in the injected region. Local inflammation was induced in the hindpaws of male mice (aged 6-8 weeks) by intraplantar injection of lambda-carrageenin. To offset the central effect of tested agents, different agents were blindly injected into the left and right paws in the pairs of comparison. The effect of dexmedetomidine on edema (increase in paw volume), the accumulation of leukocytes, and production of tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2) were evaluated after carrageenin injection, using water displacement plethysmometry, histological imaging, immunohistochemistry, and Western blotting analysis. Furthermore, we also evaluated the effect of yohimbine, a full antagonist of α2-adrenoceptors, and phenylephrine, an agonist of the α1-adrenoceptor, on dexmedetomidine's action on inflammatory responses. Paw volume and amount of leukocytes in the injected region significantly increased after the injection of carrageenin. Similarly, TNF-α and COX-2 production was found in the subcutaneous region injected with carrageenin, 4 hours after injection. Dexmedetomidine significantly inhibited all increases in paw volume, leukocytes, and production of TNF-α and COX-2. Furthermore, yohimbine significantly antagonized the anti-inflammatory effects of dexmedetomidine, whereas phenylephrine did not significantly alter them. The findings suggest that locally injected dexmedetomidine exhibits an anti-inflammatory effect against local acute inflammatory responses, mediated by α2-adrenoceptors.Anesthesia and analgesia 02/2014; 118(2):473-80. · 3.08 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Adenoid cystic carcinoma (ACC) is one of the most common salivary gland malignant tumors with a high risk of recurrence and metastasis. Current studies on cancer stem cells (CSCs) have verified that CSCs are the driving force behind tumor initiation and progression, suggesting that new cancer therapies may be established by effectively targeting and killing the CSCs. The primary goal of this study is to investigate the expression patterns of ABCG2, CD133, and podoplanin in ACC of minor salivary glands by immunohistochemistry analysis. We found that ABCG2 was weakly expressed in normal looking salivary gland tissues. A significant upregulation of ABCG2 expression in ACC was observed with a similar expression pattern of Ki-67. CD133 was detected in apical membrane of epithelial cells and podoplanin was expressed positively in myoepithelial cells of both normal looking tissue and ACC. However, no significant difference was found of the expression pattern of CD133 and podoplanin between normal looking tissues and ACC. Our observations suggest that CSCs may exist in quiescent cells with ABCG2 positive staining, which are surrounded by cells with positive expression of ABCG2 and Ki-67 in ACC, and costaining with ABCG2 and Ki-67 may help predict the location of CSCs.BioMed research international. 01/2014; 2014:132349.
Article: Fibrous dysplasia of the maxilla: a case report together with its conventional imaging and dynamic magnetic resonance imaging findings[Show abstract] [Hide abstract]
ABSTRACT: We previously reported that dynamic contrast-enhanced MRI parameters and time–signal intensity curves (TICs; also known as contrast index curves) are useful for the differential diagnosis of jawbone lesions. In particular, odontogenic fibroma and ossifying fibroma, which possess similar histopathological features (i.e., a mixture of hard and soft tissue components), display unique TIC patterns, and we consider that the TIC patterns of these lesions reflect their hard and soft tissue components. Therefore, fibrous dysplasia, which contains fibrous tissue and immature isolated trabeculae composed of woven bone, is expected to display an interesting TIC. The purpose of this study was to assess the utility of TICs for differentiating between the abovementioned lesions, which have similar histopathological components.Oral Radiology 01/2014; 30(1). · 0.17 Impact Factor
Article: RANK, RANKL and OPG in recurrent solid/multicystic ameloblastoma: their distribution patterns and biological significance[Show abstract] [Hide abstract]
ABSTRACT: Objectives To determine the distribution patterns of bone resorption regulators, RANK, RANKL and OPG in recurrent ameloblastomas (RA) and to clarify their impact on the biological behavior of these neoplasms. Materials and methods Fifteen paraffin-embedded RA cases were subjected to immunohistochemistry for expression of RANK, RANKL and OPG. Results RANK-RANKL-OPG triad was heterogeneously detected in RA samples. RANK, essential for osteoclast differentiation, was strongly expressed in tumoral epithelium. Conversely, RANKL, an osteoclast activator, was markedly underexpressed, and protein localization was predominantly stromal. OPG, an osteoclastogenesis inhibitory factor, was detected in neoplastic epithelium>stroma, suggesting functional inactivation of RANKL. Most RA (n=12/15; 80%) exhibited a bimolecular spatial expression pattern, the most common being RANK-positive/OPG-positive(n=8/15; 53.3%). All three proteins showed no significant correlation with the clinical/histopathological parameters in RA patients(P>.05) Conclusions The RANK+/RANKLlow/-/OPG+ phenotype observed in RA suggests an altered local bone metabolism characterized by low bone resorptive activity in these recurrent tumors.Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 01/2014; · 1.50 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Nestin is an intermediate filament that was first identified in neural progenitor cells. It is expressed in various cell types in the nervous system as well as in other systems. In the present study, we investigated nestin expression in non-neoplastic salivary gland tissue and in salivary gland tumors. In non-neoplastic salivary glands, nestin expression was observed in only a few abluminal cells. In contrast, diffuse nestin staining was observed in the abluminal cells of pleomorphic adenoma (11 of 11 cases), basal cell adenoma (7 of 7 cases), and epithelial-myoepithelial carcinoma (2 of 2 cases). The stromal cells in basal cell adenoma also expressed nestin. In adenoid cystic carcinoma (6 of 7 cases) and polymorphous low-grade adenocarcinoma (3 of 3 cases), nestin positive cells were observed focally. Nestin was not detected in Warthin tumor (6 cases), classical acinic cell carcinoma (2 cases), mucoepidermoid carcinoma (5 cases), or salivary duct carcinoma (4 cases). Because the nestin expression pattern in each histological salivary gland tumor type is unique, nestin could be a very useful abluminal cell marker for the diagnosis of salivary gland tumors.Pathology International 10/2013; 63(10):496-501. · 1.72 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: In recent years, artificial biological materials have been commonly used for the treatment of bone tissue defects caused by trauma, tumors, or surgical stress. Although tricalcium phosphate (TCP) is a promising absorbent bone tissue reconstruction biomaterial, it has been reported that its biocompatibility and osteoconductivity depend on its preparation method and sintering temperature. In addition, although it is thought that the microenvironment produced by the extracellular matrix plays an important role in cell growth and differentiation, there have been few studies on how the geometric structure of artificial biological materials affects cells. In the present study, a new honeycomb TCP scaffold containing through-holes with diameters of 300 µm has been developed. The influence of the sintering temperature on the crystal structure and material properties of the honeycomb TCP scaffold was investigated using scanning electron microscopy and X-ray diffraction. Its biocompatibility and osteoconductivity were also evaluated by implantation into experimental animals. It was found that a β-TCP scaffold sintered at 1200°C exhibited high biocompatibility and osteoconductivity, and when it was loaded with BMP-2, it exhibited both osteoconductivity and osteoinductivity, promoting rapid bone formation in both ectopic and orthotopic areas. It is thus a highly promising bone reconstruction material that is expected to find clinical applications. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.Journal of Biomedical Materials Research Part A 09/2013; · 2.83 Impact Factor
Article: Improvement of the Efficacy of 5-aminolevulinic Acid-mediated Photodynamic Treatment in Human Oral Squamous Cell Carcinoma HSC-4.[Show abstract] [Hide abstract]
ABSTRACT: Ever since protoporphyrin IX (PpIX) was discovered to accumulate preferentially in cancer cells after 5-aminolevulinic acid (ALA) treatment, photodynamic treatment or therapy (PDT) has been developed as an exciting new treatment option for cancer patients. However, the level of PpIX accumulation in oral cancer is fairly low and insufficient for PDT. Ferrochelatase (FECH) and ATP-binding cassette transporter G2 (ABCG2) are known to regulate PpIX accumulation. In addition, serum enhances PpIX export by ABCG2. We investigated here whether and how inhibitors of FECH and ABCG2 and their combination could improve PpIX accumulation and PDT efficacy in an oral cancer cell line in serum-containing medium. ABCG2 inhibitor and the combination of ABCG2 and FECH inhibitors increased PpIX in the presence of fetal bovine serum (FBS) in an oral cancer cell line. Analysis of ABCG2 gene silencing also revealed the involvement of ABCG2 in the regulation of PpIX accumulation. Inhibitors of FECH and ABCG2, and their combination increased the efficiency of ALA-PDT even in the presence of FBS. ALA-PDT-induced cell death was accompanied by apoptotic events and lipid peroxidation. These results suggest that accumulation of PpIX is determined by the activities of ABCG2 and FECH and that treatment with a combination of their inhibitors improves the efficacy of PDT for oral cancer, especially in the presence of serum.Acta medica Okayama 06/2013; 67(3):153-164. · 0.65 Impact Factor
Article: Establishment of odontoblastic cells, which indicate odontoblast features both in vivo and in vitro.[Show abstract] [Hide abstract]
ABSTRACT: Tooth tissue engineering offers very attractive perspectives for elaboration of regenerative treatments, which enables to cure tooth loss and restore quality of life of the patients. To elaborate such treatment, isolation and culture of dental pulp cell must be achieved as a key element. In this article, we report the establishment of a stable cell line from GFP transgenic rat dental pulp, named TGC (Tooth Matrix-forming, GFP Rat-derived Cell). TGCs have exhibited odontoblastic feature both in vitro and in vivo. In vitro, TGC exposed to osteogenic medium demonstrated collagen fiber synthesis with matrix vesicle and mineralization and formed a sheet-like substrate on the cell culture dish. Increased ALP activity and elevated transcription level of various genes involved in calcification and dentin formation were also observed. In vivo, transplanted TGC in SCID mice with β-TCP particles formed dentin-like and pulp-like structure with lining odontoblast. Notably, even after up to 80 passages, TGCs retain their morphological features and differentiation ability. To our knowledge, this is the first report of a dental pulp-derived cell with such stable odontoblastic characteristics. TGC could be a very useful model for further study on dental pulp cell.Journal of Oral Pathology and Medicine 05/2013; · 2.06 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE: To evaluate the diagnostic value of magnetic resonance imaging (MRI) for odontogenic tumours. MATERIALS AND METHODS:51 patients with odontogenic tumours were subjected to pre-operative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (UΣ) was calculated and then their UΣ values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCE-MRI), their CImax (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax × 0.90), Tpeak (the time when CImax occurred) and CI300 values (i.e. the CI observed at 300 s after contrast medium injection) were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters. RESULTS: Significant differences between the UΣ values of the ameloblastomas and KCOT were observed on T1 weighted images (T1WIs), T2 weighted images (T2WIs) and short TI inversion recovery (STIR) images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A: CIpeak > 2.0 and Tpeak < 200 s, Type B: CIpeak < 2.0 and Tpeak < 200 s, Type C: CI300 > 2.0 and Tmax < 600 s, Type D: CI300 > 2.0 and Tmax > 600 s and Type E: CI300 < 2.0 and Tmax > 600 s. CONCLUSION: Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.Dentomaxillofacial Radiology 03/2013; · 1.27 Impact Factor
Article: Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells.[Show abstract] [Hide abstract]
ABSTRACT: Oral squamous cell carcinoma (OSCC) is thought to arise as the result of cumulative genetic or epigenetic alterations in cancer-associated genes. We focused on the Dickkopf-3 (Dkk-3) gene as a candidate tumor suppressor in OSCC. Dkk-3 is a potential tumor suppressor, and its downregulation has been reported in various types of malignancies. However, our previous data demonstrated that the Dkk-3 protein was dominantly expressed in OSCC tissue, and its expression was correlated with a high incidence of metastasis and with poor prognosis. In order to explain this paradox, we performed functional analyses of the Dkk-3 gene in cancer cell lines. RT-PCR revealed that Dkk-3 mRNA expression was observed in OSCC-derived cell lines but not in gastrointestinal or colorectal adenocarcinoma‑derived cell lines. The siRNA for Dkk-3 was transfected into Dkk-3-expressing cells, and the changes in cell proliferation, invasion and migration were assessed. The knockdown of Dkk-3 mRNA by siRNA transfection did not affect cell proliferation, but it significantly decreased cell migration and invasion. To further investigate the precise mechanism that contributes to the potential oncogenic function of Dkk-3, the Wnt canonical pathway and non-canonical pathways were assessed. Western blotting demonstrated that the effect of Dkk-3 knockdown on cell migration or invasion was not caused by activation of the Wnt pathways. These data demonstrated that Dkk-3 expression in OSCC was different than that in adenocarcinomas. Dkk-3 may possess an oncogenic function that is independent of Wnt signaling.Oncology Reports 01/2013; · 2.30 Impact Factor
Article: Expression and roles of CCN2 in dental mesenchymal cells in primary culture—With findings in a case of odontogenic myxofibroma[Show abstract] [Hide abstract]
ABSTRACT: Purpose of the research Tooth germ development involves multiple events, including cell proliferation and cell differentiation. Connective tissue growth factor (CTGF/CCN2) is a signaling protein involved in tooth germ development, and we investigated how it is expressed and what roles it may have in primary cultures of mesenchymal cells derived from the developing tooth germ. We also examined the expression of CCN2 in a human odontogenic myxofibroma, a benign tumor of odontogenic mesenchymal origin, and considered the possible roles of CCN2 in the development of myxofibromas. Materials and methods Mesenchymal cells of early bell-stage tooth germs were isolated from Day-90 bovine embryos and placed in primary culture. A resected specimen from a patient with odontogenic myxofibroma was prepared for immunohistochemical studies. Principal results The CCN2 expression level in proliferating odontogenic mesenchymal cells freshly isolated from the early bell stage of developing bovine tooth germs and placed in primary culture was 3 times higher than that in the confluent non-proliferating cells. Recombinant CCN2 significantly increased the proliferation and type I collagen expression in odontogenic mesenchymal cells in primary culture. Immunohistochemical analysis on myxofibroma case revealed that CCN2 was detectable in MIB-1, a cellular marker of proliferation-positive odontogenic mesenchymal cells adjacent to capillary blood vessels and in the endothelial cells of the vessels in the tumor. Major conclusion CCN2 signaling would influence the proliferation of and extracellular matrix production by dental mesenchymal cells. Our results suggest that the same mechanisms of CCN2 action toward dental mesenchymal cells would also be operative in the odontogenic myxofibroma microenvironment.International Journal of Oral Science 01/2013; · 2.72 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The purpose of this study was to evaluate the radiological and histopathological findings of 11 patients with unerupted first molars to verify the factors obstructing spontaneous eruption. The patients' clinical, radiological, and histopathological data were evaluated retrospectively to determine histopathological diagnosis, radiographic findings, methods of surgical management, and postoperative course. This study involved 4 male and 7 female patients (mean age=9.5 years old). Nine cases involved the mandible. The patients' histopathological diagnoses included 3 odontogenic tumors, 2 odontogenic cysts, and 6 hyperplastic dental follicles. Radiographically, 10 cases showed characterless enlargement of the follicular space, while only 1 displayed radiopaque bodies. One patient with a tumor underwent enucleation, and 1 with a cyst underwent cystectomy and tooth extraction. The others underwent wide excision or partial excision of the surrounding tissue at the top of the impacted tooth. Tumor relapse was observed in 3 cases. Surgeons should perform aggressive treatment for patients with unerupted teeth because spontaneous eruption is rare in cases involving non-neoplastic lesions such as hyperplastic dental follicles.Pediatric dentistry. 01/2013; 35(1):67-70.
Article: Promotion of Transplanted Bone Marrow-derived Cell Migration into the Periodontal Tissues due to Orthodontic Mechanical Stress.[Show abstract] [Hide abstract]
ABSTRACT: Background: Bone marrow-derived cells (BMCs) have abilities of cell migration and differentiation into tissues/organs in the body and related with the differentiation of teeth or periodontal tissue including fibroblasts. Then, we examined the effect of orthodontic mechanical stress to the transplanted BMC migration into periodontal tissues using BMC transplantation model. Material and Method: BMC from green fluorescence protein (GFP) transgenic mice were transplanted into 8-week-old female C57BL/6 immunocompromised recipient mice, which had undergone 10 Gy of lethal whole-body-irradiation. Five mice as experimental group were received orthodontic mechanical stress using separator between first molar (M1) and second molar (M2) 1 time per week for 5 weeks and 5 mice as control group were not received mechanical stress. The maxilla with M1 and M2 was removed and was immunohistochemically analyzed using a Dako Envision + Kit-K4006 and a primary anti-GFP-polyclonal rabbit antibody. Immunohistochemically stained was defined as positive area and the pixel number of positive area in the periodontal tissue was compared with the previously calculated total pixel number of the periodontal tissue. Results: The immunohistochemistry revealed that GFP positive cells were detected in the periodontal tissues, both in the experimental and control specimens. The ratio of pixel number in the examination group showed 5.77 ± 3.24 % (mean ± SD); and that in the control group, 0.71±0.45 % (mean ± SD). The examination group was significantly greater than that of control group (Mann-Whitney U test: p<0.001). Conclusion: These results suggest that orthodontic mechanical stress accelerates transplanted BMC migration into periodontal tissues.International journal of medical sciences 01/2013; 10(10):1321-6. · 2.07 Impact Factor
Article: The Role of Bone Marrow-Derived Cells During the Bone Healing Process in the GFP Mouse Bone Marrow Transplantation Model.[Show abstract] [Hide abstract]
ABSTRACT: Bone healing is a complex and multistep process in which the origin of the cells participating in bone repair is still unknown. The involvement of bone marrow-derived cells in tissue repair has been the subject of recent studies. In the present study, bone marrow-derived cells in bone healing were traced using the GFP bone marrow transplantation model. Bone marrow cells from C57BL/6-Tg (CAG-EGFP) were transplanted into C57BL/6 J wild mice. After transplantation, bone injury was created using a 1.0-mm drill. Bone healing was histologically assessed at 3, 7, 14, and 28 postoperative days. Immunohistochemistry for GFP; double-fluorescent immunohistochemistry for GFP-F4/80, GFP-CD34, and GFP-osteocalcin; and double-staining for GFP and tartrate-resistant acid phosphatase were performed. Bone marrow transplantation successfully replaced the hematopoietic cells into GFP-positive donor cells. Immunohistochemical analyses revealed that osteoblasts or osteocytes in the repair stage were GFP-negative, whereas osteoclasts in the repair and remodeling stages and hematopoietic cells were GFP-positive. The results indicated that bone marrow-derived cells might not differentiate into osteoblasts. The role of bone marrow-derived cells might be limited to adjustment of the microenvironment by differentiating into inflammatory cells, osteoclasts, or endothelial cells in immature blood vessels.Calcified Tissue International 12/2012; · 2.75 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to determine the expression of essential osteogenic genes related to the canonic WNT pathway, i.e., WDR5, sFRP-2, and their downstream genes, in ameloblastoma and to clarify their biologic impact on this neoplasm. Forty-six paraffin-embedded ameloblastoma samples and ameloblastic (AM-1) and preosteoblastic (KUSA/A1) cell lines were used. Immunohistochemistry, Western blot, reverse-transcription polymerase chain reaction, and alkaline phosphatase (ALP) activity assay were performed. WDR5, essential for osteoblast differentiation and canonic WNT pathway activation, was negative in most ameloblastoma cases and weakly expressed in AM-1 cells. Conversely, sFRP-2s was overexpressed. RUNX2 and C-MYC, downstream inductions of canonic WNT pathway activation, demonstrated weak mRNA expressions in ameloblastoma, suggesting WNT pathway impairment and WDR5 functional inactivity. Recombinant WDR5 weakly induced ALP activity of KUSA/A1 cells cultured in AM-1 conditioned medium. These findings suggest that WNT-related bone-forming genes are down-regulated in ameloblastoma. Concurrent sFRP-2 overexpression suggests that both bone-forming and bone-inhibiting genes equally contributed to reduced bone formation in this neoplasm.Oral surgery, oral medicine, oral pathology and oral radiology. 12/2012; 114(6):771-7.
Article: Ossifying fibroma of the maxilla: a case report including its imaging features and dynamic magnetic resonance imaging findings.[Show abstract] [Hide abstract]
ABSTRACT: Ossifying fibroma (OF), a rare nonodontogenic tumor, is defined as a bone-related jawbone lesion. The main histopathological feature of OF is the replacement of bone by benign connective tissue. Ossifying fibroma usually occurs in the second to fourth decades of life and shows a predilection for females. Ossifying fibroma most commonly occurs in the mandible, and OF arising from the anterior part of the maxilla is rare. Ossifying fibromas display various radiographic findings, including varying degrees of radiolucency and radiopacity, depending on the proportions of their soft and hard tissue components. Depending on their components, it can be difficult to distinguish OF from other fibroosseous lesions and some odontogenic tumors by using conventional radiographs, computed tomography, and magnetic resonance imaging (MRI). We report a case of OF in the anterior maxilla in a 56-year-old man, together with its histopathological and imaging findings including the dynamic MRI findings.Oral surgery, oral medicine, oral pathology and oral radiology. 10/2012; 114(4):e139-46.
Article: Solid-type primary intraosseous squamous cell carcinoma of the mandible: a case report with histopathological and imaging features.[Show abstract] [Hide abstract]
ABSTRACT: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant odontogenic tumor arising from odontogenic epithelial remnants within the jawbones. PIOSCC is histopathologically divided into 3 types: solid-type carcinoma, carcinoma derived from a keratocystic odontogenic tumor, and carcinoma derived from an odontogenic cyst. In this article, we report a case of solid-type PIOSCC involving reactive bone formation in the mandible in a 60-year-old female patient together with its histopathological and imaging findings.Oral surgery, oral medicine, oral pathology and oral radiology. 09/2012; 114(5):e71-7.
Top Journals
Matsumoto Dental University
Shiojiri, Nagano-ken, Japan
- • Department of Oral Physiology
- • Institute for Oral Science
- • Division of Hard Tissue Research
- • Department of Oral Pathology
- • Division of Oral and Maxillofacial Biology
Ohu UniversityHukusima, Fukushima, Japan
Okayama University
Okayama, Okayama, Japan
- • Department of Oral Pathology and Medicine
- • Department of Gastroenterological Surgery, Transplant, and Surgical Oncology
- • Department of Pathology and Oncology
Tokushima Bunri University
Tokushima-shi, Tokushima-ken, Japan
- Faculty of Pharmaceutical Sciences
University of Malaya
Kuala Lumpur, Kuala Lumpur, Malaysia
- • Department of Oral Pathology & Oral Medicine & Periodontology
- • Faculty of Dentistry
Wakayama Medical University
Wakayama, Wakayama, Japan
- Department of Otolaryngology-Head and Neck Surgery
Nagoya City University
Nagoya, Aichi, Japan
- Department of Pathology
Yamaguchi University
Yamaguti, Yamaguchi, Japan
- Division of Oral and Maxillofacial Surgery
New York University College of DentistryNew York City, New York, United States
Kyungpook National University
Daikyū, Daegu, South Korea
- Department of Oral Pathology


text:
TNGOs' Central Union executive meeting at TNGOs' Bhavan
Hyderabad 8th April (QSA) Today 8th april TNGOs Central Union Executive Meeting was held at TNGOs Bhavan Nampally, Devi Prasad Central Union President, S.M.Hussaini Mujeeb Hyderabad district President and others attended the meeting.
|M.Ashok kumar says...
|my name M.Ashok kumar(telangana computer teachers president).i want to u meet sir.
|chandrashekarreddy says...
|i chandrashekarreddy.i want to meet jac chairman its to urgent about 2008 dsc rrdist it a fack dsc in that deo cheted all and also law we have profs ple help me sir my phone no.9000682062
Related Articles:
Beautification of Road from HACA Bhavan to GHMC Head Office completed successfully at Hyderabad
|Hyderabad 7th November, 2014: Somesh Kumar, Commissioner, GHMC has inspected the road from HACA Bhavan to GHMC Head Office on 31st October, 2014. To t
More Hyderabad News
|Tollywood celebs at Bham Bolenath trailer release function
|AR constable Obulesh produced at Nampally court in Hyderabad
|Congress activists burn effigy of Ashok Gajapathi to protest naming of airport after NTR
|M Narasimhulu fast in favour of naming of airport after N.T. Rama Rao
|Congress leaders demonstration against renaming of Shamshabad airport
|Police Commissioner Mahender Reddy at a press conference
|Gunman opens fire from AK47 on Aurobindo Pharma director K. Nityananda Reddy in Hyderabad

subset: commoncrawl


text:
Thousands of Guineans Displaced by Ebola-Linked Unrest
World | Agence France-Presse | Wednesday November 12, 2014
A group of Guinean activists went on hunger strike on Tuesday to demand the safe return of thousands of villagers they say have fled their homes amid Ebola-related unrest in the south.
Woman Jailed in Iran For Watching Men's Volleyball Declares Hunger Strike
World | Agence-France Presse | Tuesday November 4, 2014
A British-Iranian woman jailed in Iran after trying to watch a volleyball match is on a hunger strike, refusing food or liquids, her brother told AFP on Monday.
Woman Jailed in Iran for Protesting Volleyball Ban Declares Hunger Strike
AgenceFrance-Presse | Tuesday November 4, 2014
British-Iranian woman Ghoncheh Ghavami is protesting because the judge is yet to officially confirm her one-year prison sentence.
Undertrial Prisoners Stage Protest Against Improper Treatment in Mathura
Cities | Press Trust of India | Wednesday October 29, 2014
Undertrial prisoners on Tuesday staged a hunger strike in Mathura jail but called it off soon after authorities promised them proper treatment.
Iranian-British Woman, Jailed for Bid to Watch Men's Volleyball, Goes on Hunger Strike
Reuters | Monday October 6, 2014
Iranian women in the Islamic Republic are banned from watching certain male sports events such as football and volleyball.
Iranian-British Woman, Jailed for Bid to Watch Men's Volleyball, Goes on Hunger Strike
World | Reuters | Sunday October 5, 2014
An Iranian-British woman has gone on hunger strike in prison in Tehran to protest against her arrest for trying to watch a men's volleyball game, the opposition website Kalame reported on Sunday.
AAP to Lead Hunger Strike by Renault-Nissan Workers
Friday September 19, 2014
Labour trouble seems to be brewing at Renault Nissan Automotive India Pvt Ltd (RNAIL) plant here with around 200 former trainees employed at the factory Friday deciding to go on hunger strike, led by Aam Admi Party (AAP).
South Korea Ferry Victim's Father Ends 45-day Hunger Strike
World | Agence France-Presse | Thursday August 28, 2014
The father of one of the high school students killed in South Korea's ferry disaster on Thursday abandoned a hunger strike aimed at forcing lawmakers to set up a full independent inquiry.
Hunger-Striking Father of South Korean Ferry Victim Hospitalised
World | Agence France-Presse | Friday August 22, 2014
The father of one of the high school students killed in South Korea's ferry disaster was hospitalised Friday after mounting a 40-day hunger strike to demand a full independent inquiry.
Irom Sharmila Continues Hunger Strike Near Jail Hospital After Release
India | Edited by Deepshikha Ghosh | Thursday August 21, 2014
Irom Sharmila, who has been on a hunger strike in Manipur for 14 years against army atrocities, is sitting on protest just half a kilometer from a jail hospital from where she was released on Wednesday.
Irom Sharmila Says Happy to be Released, But Will Continue Fast
India | Reported by Monideepa Banerjie, Edited by Deepshikha Ghosh | Thursday August 21, 2014
Irom Sharmila, who has been on a hunger strike in Manipur for 14 years, will be released shortly from a hospital room where she has been kept for years.
Irom Sharmila Must Be Released, Says Court, Rejects Attempted Suicide Charges
India | Reported by Alok Pandey, Edited by Deepshikha Ghosh | Tuesday August 19, 2014
Irom Sharmila, who has been on a hunger strike in Manipur for 14 years, will be released, a local court said today.
Novice Matadors' Hunger Strike over Bullfight Ban in Colombia
World | Associated Press | Monday August 18, 2014
Two years after Bogota's leftist mayor suspended bullfights at the capital's history-steeped bullring, a clutch of apprentice matadors is pressing for their reinstatement with a hunger strike.
Force-Fed Gitmo Prisoner's Life at Risk: Attorney
World | Associated Press | Wednesday August 6, 2014
The attorney for a Guantanamo Bay prisoner from Syria cleared for release in 2009 says his health has deteriorated severely as a result of an ongoing hunger strike.
Navy Nurse Refuses to Force-Feed Gitmo Detainees
World | Associated Press | Wednesday July 16, 2014
A US Navy nurse has refused to force-feed prisoners who are on an extended hunger strike at Guantanamo Bay, the first protest of its kind at the detention centre, a rights lawyer and US official said on Tuesday.
Digvijaya Singh to Stage Week-Long Hunger Strike in Guna
India | Edited by Zoya Anna Thomas (with PTI inputs) | Monday July 7, 2014
Congress General Secretary Digvijaya Singh will stage a seven-day hunger strike at the Guna district headquarter in Madhya Pradesh starting today. He is protesting against the state government for not providing relief to natural-calamity hit farmers.
Digvijaya Singh to Stage Hunger Strike in Madhya Pradesh's Guna
India | Press Trust of India | Saturday July 5, 2014
Congress General Secretary Digvijaya Singh today said he will stage a seven-day hunger strike in Guna district headquarter from July 7, to protest against the state government for not providing relief to farmers hit by natural-calamity.
Palestinians Halt 62-Day Hunger Strike After Deal
World | Agence France-Presse | Wednesday June 25, 2014
Sixty-three Palestinian prisoners who have refused food for 62 days have suspended their hunger strike after reaching a deal with the Israel Prisons Service, their lawyer told AFP.
Egypt Frees Al Jazeera Journalist on Hunger Strike
World | Reuters | Tuesday June 17, 2014
Egypt's public prosecutor ordered the release on Monday on medical grounds of Al Jazeera journalist Abdullah Al-Shamy, who had been on hunger strike for more than 130 days in protest over his detention, a statement from the prosecutor's office said.
Thai Hunger-Striker Files Charges Against Junta Leader
World | Reuters | Tuesday June 10, 2014
A Thai political activist who has started a hunger strike in protest against last month's coup filed charges on Tuesday against junta leader Prayuth Chan-ocha and members of the ruling military council for defaming the monarchy and acts of treason.


text:
Paris Jackson Posts Michael Jackson-Debbie Rowe Photo, Pays Tribute to Late Fatherby Free Britney at . Comments
On the third anniversary of Michael Jackson's death, his daughter Paris is still mourning his loss, while remembering all the good times she had with him.
The pop star's only daughter, now 14, paid tribute Monday morning, tweeting, "RIP Michael Jackson ... Dad you will forever be in my heart."
Paris also Tweeted a pic of Michael with Debbie Rowe, the nurse who famously wed Jackson in 1996 and bore two children, Paris and Prince Michael.
Mommy and daddy <3," Paris wrote in a caption of the pic:
Debbie Rowe married Michael Jackson in 1996. The couple divorced in 1999, after which she gave full custody of both Prince and Paris to the pop icon.
Dr. Arnold Klein, Jackson's longtime friend, has long been rumored to be the biological father of both children, although this has never been proven.
MJ's third child, Blanket, was born in 2002 via an unknown surrogate.
Whatever you might think of him, he apparently excelled at parenting. Paris, Prince and Blanket have gone on to become outstanding young people.
I think the Hollywood Gossip needs to report Jawny to the police. Sick freak.
Hope the best for all of Jacksons,they reflect the true American life-rags to riches.and they never committing crimes.
Michael was a gifted HUMAN BEING whom the media murdered years before his doctor did. RIP KING OF POP ROCK & SOUL. You are missed.
Shut da hell up terri!! Fuckn moron!
Shame on you, Terri. He was a good person who donated hundreds of millions of dollars to charities all over the world. He did an amazing job raising his three children, and now that he's gone, his children are a testament to what a good father he really was.
Hes a ghoul.


text:
Q: What do you do when your 5,000-word "Tiger Woods is the Greatest Athlete of all time" column gets Yanged on Sunday afternoon?
A: You pump out a Red Sox report card!
My own fault, I was overconfident after Friday and assumed that we would spend the weekend watching a Tiger double-digit victory. Lesson learned.
So the focus here will be on the Sox, who have about a lap to go in the 2009 mile. This is my second report card of the season (for those of you who failed to bookmark it, here's the first), and as you'd expect there have been more than a few changes.
All stats are through 8/17 (and fire away at firstname.lastname@example.com if you disagree with any grades handed out)…
Josh Beckett (A)
Untouchable the last four months. He has killed righties this year, holding them to a .244 on-base percentage.
I don't know if he's going to win the Cy Young Award (if the season ended today I'd still vote Halladay -- better ERA than Beckett plus leads the league in WHIP) but if you're a Sox fan I understand why you'd think this is the best pitcher in baseball.
Beckett has been so good this season that you can almost ignore that the guy you traded to get him has become maybe the best player in the world. Has there ever been a deal that has worked out so well for both teams? Plus a World Series MVP as a throw-in? I'm serious; name me another trade that comes close. The test is this: knowing what you know today, if you could jump into the DeLorean and go back to November 24th, 2005, would you still do the Ramirez/Beckett deal? I'm thinking most Sox fans would.
Hideki Okajima (A-)
How about these numbers against left-handers?
.161 batting-average against
.207 on-base percentage
.253 slugging percentage
Basically, all lefties have been Jason Varitek against Okajima this season.
Kevin Youkilis (A-)
My MVP ballot (if the season ended today, of course).
10. Carl Crawford
8. Ichiro
7. Derek Jeter
6. Michael Young
1. Joe Mauer
(If I had done this two months ago, it would have been a coin flip between Mauer and Jason Bay for the top spot.)
So the Red Sox went 2-3 during Youkilis' suspension. Can we finally put to rest the notion that these fights will do anything but hurt a team? These are grown men. I've never bought that they needed a "spark" or a wake-up call. C'mon. Varitek fighting A-Rod in 2004 had nothing to do with the team winning the World Series that year, yet I still read and hear about how that was a defining moment (for instance...). If that was the case, why did the Sox fall down 3-0 in the ALCS? Did they forget there was a fight until Game 4?
Jason Bay (B+)
Remember, this is for the season as a whole. I know he was terrible in June and July, but he's bounced back in August (1.268 OPS).
Bay's on pace for 35 homers, 118 RBI and 104 walks. That's a season that would fit right in the middle of Manny Ramirez's baseball-reference page, right? Is there anyone that would not have signed up for those numbers from Bay before the season started?
Ramon Ramirez (B+)
Ramirez's WHIP by month:
April: .730
May: 1.024
June: 1.250
July: 1.548
August: 1.696
Not sure what role he'll play the rest of the way, but this has been a good deal for the Sox. Haven't heard much clamoring for Coco Crisp (hit .228 with a slugging percentage of .378 before he went down) lately.
Victor Martinez (B+)
When the Red Sox acquired Victor Martinez on July 31st they were 60-42, a game and a half behind the Yankees and a game and a half ahead in the wild card standings. Now they are 66-51, seven and a half games behind the Yankees (through Sunday) and would be out of the playoffs if the season ended today. All this has happened with Martinez hitting .311 with an .891 OPS in 14 games with the Sox. I'm not sure there's a point to be made here, it's just been a strange few weeks is all.
Daniel Bard (B)
Should he have a higher grade? Maybe, I think I'm hitting him too hard for the meltdown at Yankee Stadium (which really was Francona's fault). How about the numbers at Fenway? He's faced 53 batters and has allowed eight hits and one walk (with 17 strikeouts). Hard to believe that Papelbon and Bard will both be here through 2011, isn't it?
Jacoby Ellsbury (B)
About as good a player with a .404 slugging percentage as you're going to find.
Looks like he's not going to walk much more than 40 times a season, but at least he's cut his K rate down a little this year (on pace for 65, had 80 in 2008). He'll need to keep doing that if he's going to hit around .300. I think there will be some years when he hits around .270 or so but he's a "leave alone" guy at CF for the next decade at least.
Jon Lester (B)
Reason No. 2 why I wouldn't give up on the Red Sox' 2009 season. If they find a way to sneak into the wild card (still better than a 50/50 shot, I think; not exactly the 1998 Yankees or 1976 Reds in the wild-card battle with the Sox) they have a chance to start Lester and Beckett (or Reason No. 1) four or five times in a seven-game series.
On May 15th Lester gave up five earned runs in five-plus innings in a loss to the Mariners. His record was 2-4 and his ERA was 6.51 and there was, to put it kindly, some doubt. Since then? 7-3 with a 2.46 ERA and 118 strikouts in 106 innings. I'm not sure there have been three better pitchers in the league in the last three months. And Beckett has matched him start for start. To be seven and a half games back and out of the playoffs shows how poorly the rest of the rotation has performed.
Mike Lowell (B)
Nice bounce-back season. After a lousy June (.206 BA, .289 OBP) I figured he was ready to take his place alongside Varitek and Ortiz in the Over The Hill Gang. But he's been the club's best hitter since the All-Star Break (1.018 OPS) and deserves to be in the lineup every day. I don't see an argument for Ortiz against righties over Lowell:
Ortiz vs. RHP: 272 at-bats, .221 BA, 12 HRs, .323 OBP, .401 slugging
Lowell vs. RHP: 239 at-bats, .301 BA, 8 HRS, .336 OBP, .481 slugging
I'll be honest – I think Luis Aponte has a better chance of being the Red Sox closer in 2012. I don't see it. Nothing against Papelbon's ability or performance level, (even though his WHIP and BB/9 numbers are easily the worst of his four seasons as a closer they are still solid) but Theo isn't going to pay $12-14 million a year for 60-70 innings. Not when he can get 80/90 percent of Papelbon from Bard at a 20th of the price. They learned their lesson from Keith Foulke. Sure, they got a great 2004, but the next two seasons were a complete wipeout and cost them $15 million bucks. Won't happen again.
Dustin Pedroia (B)
Maybe Pedroia plays 20 years and never has a season as good as 2008. It's possible, but he's already done enough in 2007 and 2009 to show that the MVP isn't a fluke. Again, I'd take 190 hits and 120 runs in any season from a second baseman, and that's just about what Pedroia is on pace for in 2009.
Takashi Saito (B)
The anti-Smoltz: a veteran pitcher with an injury history that signed for short money and has panned out for the most part.
Can't figure out why he's had trouble vs. righties this season (.300 BA against) while dominating left-handed hitters (.181 BA against). Nothing in his history to suggest that this was going to happen. Of course, I also can't figure out why ESPN needs to list every cast member of the new season of Dancing With the Stars on the scroll, or why my cousin's wife needs to update her Facebook page with the following:
"Got the mail. Bills and some junk. Probably will wait until Wednesday to check again."
Maybe the loneliest near-haiku ever written.
Tim Wakefield (B-)
Remember him? The Sox need Knucksie to come back and play the role of Good Tim Wakefield, the guy who allows three runs over six starts and carries the team for a month. If they get six or seven starts from Evil Tim Wakefield -- the guy so bad that he can't crack playoff rosters -- then the season might be over.
Clay Buchholz (or, our generation's Herb Washington) (C+)
If the playoffs started today (and the Red Sox were in them, of course) here is your Game 3 starter.
I'm not sure why I keep thinking Buchholz is 21 or 22 years old. He's 25, or the same age as Scott Kazmir, Tim Lincecum, Matt Cain and Jon Lester. The training wheels are off now, and we'll see what we've got over the next year or so. Figure Penny will be gone after this season, so this looks like the rotation in 2010.
Manny Delcarmen (C)
Manny Delcarmen in 2007: 44 innings pitched, 28 hits allowed, 17 walks, 41 Ks
Manny Delcarmen in 2009: 47.2 IP, 47 hits allowed, 25 walks, 32 Ks
Probably the easiest player to grade, actually. He's had pretty much the definition of an average season for a relief pitcher. Is it a step back? I guess. He was great in 2007 and really good in 2008 so you'd have to be a little surprised. But every reliever not named Mariano Rivera has mixed in at least the occasional off season. If Delcarmen's numbers continue to slip in 2010 then we've got a story.
Brad Penny (C-)
OK, he's stayed healthy. Great. But that's really about it if you want to present the case for Penny in 2009. Even when it was going well for him (3.18 ERA in June) you got the feeling he was putting band-aids on bullet wounds. The guy gives up a TON of hits (150 in 127.2 innings) and his K/BB rate is below average. Not a good combination. If Daisuke or Wakefield were healthy and Smoltz hadn't been a disaster, Penny would have been dealt or in the bullpen. But you need a little luck to stick around, I guess. How else did Seth Green ever have a career?
J.D. Drew (D+)
This only works if you tell the joke in your Jay Leno voice:
"Strange move by Denny's today, given the economy. They introduced the J.D. Drew Grand Slam, which costs $70 million and gives you nothing else. See, Kevin, because he hit a grand slam in a big game and makes a lot of money…"
Johnny Damon with the Yankees (3+ years): 541 games, 75 homers, 386 runs, .286 BA, .463 slugging.
J.D. Drew with the Red Sox (2+ years) 349 games, 43 homers, 225 runs, .269 BA, .462 slugging.
In fairness, Drew has an edge in OBP and OPS, but at best he's been a wash with Damon. As I've written before, if Drew was signed to a reasonable contract ($8-9 million a year) nobody would ever mention him. But the Red Sox have paid Drew $14 million a year to do his best Matt Stairs impression (okay power, decent OBP, nothing else).
Nick Green (D+)
Had a solid May (.321 BA), but things have gotten Health Care Town Meeting ugly since, with an OBP of .288 in June, .222 in July and .267 so far in August. So I guess bringing in Alex Gonzalez and his .254 OBP is an upgrade, if only because of his prowess on defense (Curt Schilling is a believer). The truth is that Green's history pointed to this dropoff, and his six weeks or so of good play early in the season was a bonus.
David Ortiz (D)
Admit it, you had August 8th in the "David Ortiz will blame this whole thing on the media" pool, didn't you? Well, he proved you wrong. Drink in the shame.
Jason Varitek (D-)
Here's what I wrote about Varitek in the Report Card from two months ago (remember, The Captain was off to a nice start):
I think the Pink Hats should maybe slow down just a little with the victory lap on this one. Sure, Varitek has hit 10 homers, but let's be honest: that is all that he has done offensively. He's a bad month away from having a .230 average with a .300 OBP at the All-Star Break. But he has been absolutely a positive to this point, and maybe he ends up with 18-20 HRs and a .240 average.
Before I give myself the full Pitino restaurant treatment, I should admit the final line of the column was this prediction:
John Smoltz after five starts? 2-1 with a 3.62 ERA.
John Smoltz (F)
Small sample size, but Smoltz had a K/BB ratio of 3.67 in his eight starts, a total that would actually rank sixth in the American League.
Couldn't Smoltz have stuck around and pitched out of the bullpen? His best numbers came in his first 25 pitches of each game (.286 slugging against), and he was tough on righties (.232 BA against). Of course, every lefty was Roy Hobbs:
Lefties against Smoltz in 2009: .440 batting average, .490 OPS, .758 slugging.
Michael Bowden, Chris Carter, Hunter Jones, Jed Lowrie, Gil Velaquez, Jeff Bailey, Casey Kotchman, Javier Lopez, Junichi Tazawa, Fernando Cabrera, Hunter Jones, Josh Reddick, Jonathan Van Every
Things Haven't Changed in the Last Two Months:
Rocco Baldelli (a "D" last time) and Daisuke Matsuzaka (an "F")
Semi-Fearless Predictions for the Final 45 (or 46) Games?
David Ortiz is benched for the final month of the season (complete with a DL stint as he "works things out").
Daisuke Matsuzaka returns to make one start before leaving the game in the fourth inning with "shoulder stiffness." He does not pitch again in 2009.
The Red Sox finish the season with a 92-70 record, good for a one-game playoff with the Rangers. Jon Lester throws seven shutout innings and Mike Lowell homers in a 4-2 win.
Patriots Insider Tom E Curran previews Pats-Packers
Michael Irvin discusses the coaching of Bill Belichick, Rodgers vs. Brady and the Thanksgiving games.
Devin McCourty joined the show to talk about Aaron Rodgers being the best quarterback they've prepared for, and what he appreciates most about working alongside Darrelle Revis.
How have the Celtics looked after a couple weeks? Could they be a playoff team? These questions and more...
Sam and Ben talk with Greg Dickerson about how fun this year's Celtics team is to watch as well Jeff Green trade ideas.
Kyle Draper joins Danny Picard to talk about the Celtics chances this season in the Eastern Conference, last Wednesday's home opener blowout against the Nets, and Rajon Rondo's future in Boston
The Red Sox trotted out their newest FA acquisition Tuesday afternoon, third baseman, Pablo Sandoval. The Kung Fu Panda then joined MFB to talk about his conversations with (former) Giant teammate, Jake Peavy, about playing Boston. He also stressed that this move was the next big challenge in his life, and addressed some concerns about his defense, stating that he is focused on being at the hot corner for the duration of his contract.
Buster Olney of ESPN joined MFB to talk about all the free agent news surrounding the Red Sox over the past 24 hours
Red Sox beat writer Brian MacPherson joins Danny Picard to talk about the Red Sox going after Jon Lester and other free agents.
Andy Brickley joined the show to talk about David Pastrnak's first game, the offensive struggles, and Milan Lucic playing with the Swedes.
Dale and Michael get Jack Edwards' 'state of the B' report and talk about the win over the Blues at the Garden on Tuesday.
Andy Brickley joined the show and touched on last night's convincing win over a good team, Matt Bartkowski needing a wake up call, and the NHL review process.
Special Teamer Don Jones was waived in a surprising move, Chandler Jones practiced and the Patriots gear up for what could be their most difficult battle left in Green Bay.
Celtics columnist, Chris Forsberg, joined Butch and Gordon Edes to talk about the young core of players, Brad Stevens' need to win, and the tough November schedule that the Celtics struggled through.
BC football sideline reporter Scott Mutryn with the worst impersonation of all time.
Adam Schefter joined the show as he does every Friday to talk about the hot streak that the Patriots are on, Brady vs. Rodgers, and the problems going on in San Francisco.
Devin McCourty joined the show to talk about Aaron Rodgers being the best quarterback they've prepared for, and what he appreciates most about working alongside Darrelle Revis.
We find out what Chris Price was right and wrong about when he made a few predictions before the Lions game. Also, we hear some new ones regarding Sunday's game against the Green Bay Packers.
Pats insider Tom E Curran previews Pats-Packers
Michael Irvin discusses the coaching of Bill Belichick, Rodgers vs. Brady and the Thanksgiving games.
We get our weekly NFL update with SI/MMQB's Peter King. Peter talks AFC East, first round byes, Jonas Gray/LeGarrette Blount and much more.
Mikey remixes Billy Joel "Movin Out" in honor of the Patriots playing the Green Bay Packers
Brandon covers the NFL, particularly the Detroit Lions for Bleacher Report. He gives us his thoughts on this Sunday's game and how the Lions stack up against the Patriots.
Mikey, Villani, Lenny and Kerry Byrne are talking Patriots-Lions and how the team this year stacks up to Patriots teams of the past.
The guys previewed the upcoming Packers Patriots game and discussed the media's latest tweet beef.
Jerry Thornton's first podcast explores sports stories that would make for interesting 30 for 30 documentaries.
Ben Cherington joined us to discuss the Sox off-season moves.More from this show
The top stories of the day.More from this show
We get our weekly NFL update with SI/MMQB's Peter King. Peter talks AFC East, first round byes, Jonas Gray/LeGarrette Blount and much more.More from this show
Dino picked the Pack.More from this show
Ashley Byrne of PETA joined the show on the proper way to celebrate Thanksgiving.More from this show


text:
Add Sale Alert
21 products
Searching ...
Sales & Deals
Create A Sale Alert
Clear All Filters
- AU Stores
- All Stores
As chosen by Allure magazine editors for 12 years, the classic Tweezerman Slant Tweezer is now available in the sophisticated and luxurious shade of emerald green. Tweezerman perfectly aligned, hand-filed tips are slanted to grab every hair, every time with amazing precision. This special edition Tweezerman Tweezer in emerald green brings luxuriant zing to your brow beauty routine. Features:Luminous emerald green: Pantone Colour of the Year in 2013 True precision with professional quality Perfectly aligned slanted tips grab every hair
Eye-Catching Pink, Award-Winning Performance Put a little spring in your step with this Tweezerman favourite in flirty, fresh geranium. Inspired by Pantone colour choices for 2012, this pretty geranium hue brings to mind pink grapefruit and sun-ripened watermelon. Brighten your beauty routine with the 'Best of Beauty' winner, the Tweezerman Slant Tweezer. Features: Perfectly aligned, hand-filed tips grab every hair True precision with professional quality Lightweight design fits easily in the hand
Mini Tweezer by Tweezerman Perfectly aligned, hand-filed tweezer tips Unrivalled precision Gabs the hair every time Embossed signature logo colour finishes ABOUT TWEEZERMAN Since the launch of the Splintertweeze in the '80s, Tweezerman have cornered the market with their slanted precision tips and bold, printed fashion-led designs. A favourite with make-up artists and models, the range has now expanded to include a selection of grooming tools, from brow mousse to eyelash curlers.Product Code: 502221
Celebrated worldwide for her joyfully over-the-top styles and rock n' roll spirit, New York fashion icon Betsey Johnson is the genuine article – just like Tweezerman. Together, this dynamic team has created what can only be fittingly called punky, poppy, pretty pluck. The Betsey Johnson Betsey Bud Slant Tweezer features Tweezerman's signature, high-quality, precision slant tips to grab every hair, every time. It is adorned with the distinctively iconic Betsey Johnson Rose Bud, which embodies the true essence of Betsey and her personality. Tip: Tweeze in the direction of hair growth to avoid breakage.
The ultimate brow perfection kit! Achieve and maintain perfect brows with this portable kit from Tweezerman. The Tweezerman Mini Brow Kit with Powder contains: - Stainless Steel Slant Tweezers - Mini Brow Powder Brush - Brow Powder Dup & Compact Mirror - Carry Case
Tweezerman Point tweezers Features:The Point Tweezer has extra-sharp, perfectly aligned hand filed points guaranteed to tweeze. Ideal for stubble and ingrown hairs. Stainless Steel. How To Use:Tweeze in the direction of hair growth, extracting one hair at a time. For ingrown hairs, cleanse skin and disinfect tip of tweezer with alcohol. After any work under the skin, clean area with hydrogen peroxide.Care:Wipe tips clean after use. Always replace protective cap on tweezer tips. C ... Read more
Tweezerman Point Tweezer $39.95 $35.96
Taking lead from Pantone's "it" colours of 2012, Tweezerman's iconic slant tweezer has had a bold and bright makeover. Tweeze to perfection with the award-winning Tweezerman Slant Tweezer in eye-catching geranium. The angled, slant tip rests comfortably against your skin for painless plucking and the lightweight design fits easily in your hand. The stainless steel is durable and quick to clean. Keep the vibrant tool in your purse or tote for easy tweezing on the go.
These wild Animal print tweezers are perfect to tame those wayward brows. A perfectly aligned hand-filed tips are slanted so that they can grab every hair every single time with precision. They are a stainless steel tool with a colour enamal finish.
Brush and shaping scissors by Tweezerman . Featuring slim scissors with a slight curve to shape and trim the eye brow across the brow bone and a spiral thick bristle mini brush to groom and define the brows. ABOUT TWEEZERMAN Since the launch of the Splintertweeze in the '80s, Tweezerman have cornered the market with their slanted precision tips and bold, printed fashion-led designs. A favoutire with make-up artists and models, the range has now expanded to include a selection of grooming tools, from brow mousse to eyelash curlers.Product Code: 177179
The Tweezerman Mirror and Tweezer Kit presents two grooming essentials in an elegant leather storage case. The Tweezerman Slant Tweezer with its carefully aligned hand-filed tips is gently slanted for easy hair removal. Here it is packaged with an optically correct 10x Mirror which makes the Tweezerman Mirror and Tweezer Kit ideal handbags or travel.
The Tweezerman Slant Tweezer is an instrument of the highest quality boasting carefully aligned hand-filed tips. Available in assorted colours – here Stainless Black - it is made of hand-polished stainless steel with a baked enamel finish. Gently slanted for easy hair removal the Tweezerman Slant Tweezer is an ideal tool for delicate plucking or removal of ingrown hairs.
Famous for its precision the Tweezerman Slant Tweezer is consistently acclaimed as setting the standard for quality and excellence. The hand-finished tips are perfectly aligned to grab the hair every time. For over 25 years the award-winning Slant has been the choice of make-up artists models celebrities and those who demand the very best. Made of hand polished stainless steel.
Tweezerman Slant Tweezers are positively the finest general-use tweezer in the world. The tips of these precise tweezers are hand-filed. This helps them to be perfectly aligned to grab the hair everytime. Once you've tried Tweezerman Tweezers, you'll never want to use anything else.
Tweezerman's famous Slant Tweezer is the finest tweezer you can own. These tweezers have been specially developed to offer perfect alignment, with hand filed tips to grab the hair everytime. The tweezers are constructed in hand polished Stainless Steel, and are designed to last. Once you've tried Tweezerman Tweezers, you will never use anything else!
- About
- Affiliate Program
- Advertising
- site map
- Contact
- terms
- privacy
- Careers
- Blog
- Brands
- Partner with ShopStyle!
- Pricing (A$)
©2014 PopSugar • PopSugar Fashion Beauty & Shopping • ShopStyle by PopSugar
invalid address
successfully added


text:
The 1st International SCANDAL Fan-Based Forum.
scandal, heaven, international, forum, fansite, jpop, album, single, song, #japan, music, band, haruna, mami, sasazaki, rina, suzuki, tomomi, ogawa, pcitures
The International Fan-Based Forum for THE GAZETTE.
sixth, guns, gazette, fadeless, band, forum, ruki, reita, uruha, international, #japan, japanese, nippon, gazetto
Gravity Pirates East Coast
gravity, pirates, downhill, east, mountian, bike, freeride, bicycle
Home of All Lolicore
lolicore, nation, underground, music, loli, guro, anime, otaku, weaboo, #japan, breakcore, speedcore, noise
Free forum : Forum for all of South Eastern Pennsylvania and surrounding areas to come together to talk about airsoft and airsoft events. Our goal is to also link together airsofters on other forums t
airsoft, sepa, forum, pennsylvania, philadelphia, montgomery, county, south, east, eastern
Free forum : ETAK is a group of people that share the same interest in Reef, Freshwater, Saltwater, Brackish, Planted, Pond..keeping
east, texas, aquarium, keepers, etak, group, people, that, share, same, interest, reef, freshwater, saltwater, brackish, planted, pond, keeping
[eCa] pub/scrim servers #eCa
Free forum : Japan Attack is a server based on Japan's drifting cultures as well as the virtual dimension abroad. Hosted by us! ! ! Team Free Spirit! ! !
free, forum, #japan, attack, forzamotorsport, virtual, drift, rfactor, server, based, japan's, drifting, cultures, well, dimension, abroad, hosted, us!!!, team, spirit!!!
Welcome to the -ATOMIC ENERGY- Community site for Navy Field .
free, forum, aef-nf, welcome, navyfield, navy, field, world, fleets, fleet, atomic, energy, wars, water, ocean, #japan, warships, warplanes
Welcome to the L. o. F. S. where far north is an everlasting winter, the east spring, south summer, and west autumn. It is here where the Wolf Kingdoms of Velheritz and Kingdom of Roenkii survive.
roleplay, land, four, seasons, wolf, wolves, lofs, velheritz, roenkii, winter, summer, magic, friendly, awesome, role, play, forumotion, forum, site, website, community, spring, autumn, fall, loafs, ajax, ocean, king
A site for gyaru
fashion, gyaru, manba, #japan, ganguro, makeup, asia, hime, banba, yamanba, koakuma, ranzuki, popteen, ageha, amekaji
Free forum : For all the Vmax lovers from the South East Queensland and Australia
Free forum : The Ultimate VW Club in East Anglia Norfolk Cambridgeshire Lincolnshire Suffolk Vw Owners Club
free, dodgy, dubbers, ultimate, club, east, anglia, norfolk, cambridgeshire, lincolnshire, suffolk, owners


text:
The fact that you can edit movies on the iPad at all is impressive. Two decades ago, non-linear editing was unheard of outside of major Hollywood film companies. iMovie on the iPad isn't a substitute for a good desktop video editing program like Final Cut Pro X or Adobe Premiere Pro CS 5.5. But it isn't mean to be. For all its limitations, iMovie for iPad is a great way to explore video editing.
Recommended Reading


text:
I helped a friend build a 5gallon stainless steel braided MLT from a cooler (FlyGuy inspired). He has brewed 3 AG batches which have turned out well. Now he wants me to help him out with a Rochefort 10 clone.
This batch which I helped scale from 5Gal to 3Gal requires about 12.5Lbs of grain with a target Pre-Boil gravity of 1.087, and Target post Boil @1.113. Will this mash be possible? Are we over capacity. I know we are getting close.
Strike is 3.6Gallons @ 165F
Sparge is 2.2Gallons @ 192F
I beleive these calculations came from his Brew Pal app.
Worse case schenario we would brew at my house with my higher capacity MLT but I would like to avoid it if possible.
Fermenting: Nothing
Secondary: Nothing
Bottled: Oatmeal Porter, Double Chocolate Chipotle Porter
Kegged: IPA, Red Rye
Thanks for the feedback, it will be a 90 min mash at 150F. His brewpot is only 20qt/5G, so I may need to bring mine.


text:
25 Years in, the Urge Still Selling Out Venues
By Melinda Cooper
The 100 Greatest St. Louis Songs
By RFT Music
"Music You Know" Draws Inspiration from the Familiar
By Allison Babka
Pokey LaFarge Signs to Rounder Records
By Daniel Hill
Miami Dolphins Is Not a Football Team
By Drew Ailes
Combating a Rash of Tour Van Break-Ins
By Brian Heffernan
Grammophone to Close, Reopen As Restaurant
By Joseph Hess
Playing for the Cause Helps Out Those in Need
By Joseph Hess
10) Nelly needs to buy a watch
I mean, come on. I know rappers are famous for showing up late, but Nelly could shoot for showing up less than an hour late to a movie. Sure, he's already seen it, but still.
11) Meeting celebrities is cool
It was hot, sticky, crowded and fake, but it was still hard to beat the glow that some stars give off. Ozzie Smith was on hand, still looking good -- and nice as hell. Yes, you had to meet those people from American Idol first, but any day when you shake hands with Smith and Rock is a good one.


text:
Yellow Cab Inc
Macon, GA
Toll-free: 800.829.4872 | Local: 478.785.1124
Call Yellow Cab Inc for cab service to all destinations in Macon, GA. Yellow Cab Inc is known for its commitment to excellence in the Macon community, and employs professional drivers who pride themselves on their extensive knowledge of the area.MASTERCARD AMEX CARD 24 HOURS Was this driver helpful? Yes No | Write a review
Radio Cab Inc
Macon, GA
Toll-free: 800.829.4872 | Local: 478.781.0076
Radio Cab Inc provides the very best quality taxi service on a consistent, reliable basis. Operating in the Macon area, Radio Cab Inc is a top choice for professional, friendly drivers, clean, safe vehicles, and superior technology.CORPORATE HYBRID TAXI LARGE CABS Was this driver helpful? Yes No | Write a review
Middle Ga Taxi Service
Macon, GA
Toll-free: 800.829.4872 | Local: 478.788.4277
Quality, professional, and punctual cab service at reasonable rates–this is what Middle Ga Taxi Service offers you. Whether you need to get to the airport, a hotel, or hospital, Middle Ga Taxi Service provides an affordable, smooth, and cozy ride.MASTERCARD INTERNET NEW CABS Was this driver helpful? Yes No | Write a review
The taxi and transportation companies that 1-800-TAXI-USA refers to by telephone, the web or otherwise, are independent companies that are not owned or operated by 1-800-TAXI-USA. Because it does not own or operate any of these companies, 1-800-TAXI-USA expressly disclaims any and all liability to anyone related to the services provided by any of these companies. The information provided by 1-800-TAXI-USA is provided by these companies, but 1-800-TAXI-USA does not guarantee it to be accurate or complete. Users must independently verify all information regarding these companies.


text:
Posted January 10, 2012 on AP on Fox
Josh McDaniels spent a chilly day on the field at his first practice since becoming an offensive assistant with the New England Patriots. They worked Tuesday on getting ready for Saturday night's divisional playoff game against the Denver Broncos, the team McDaniels coached in 2009 and for the first 12 games in 2010 before being fired. He had spent three seasons as New England's offensive coordinator before moving to Denver. McDaniels could provide some inside information on the Broncos, but the Patriots already know plenty about them from studying video of them and having played them on Dec. 18. The Patriots hired McDaniels last Sunday after the St. Louis Rams released him from the final year of his contract as offensive coordinator.
Original Story: http://msn.foxsports.com/nfl/story/Mc...
PLAYERS: Josh Mcdaniels
TEAMS: Denver Broncos, New England Patriots, St. Louis Rams
TEAMS: Denver Broncos, New England Patriots, St. Louis Rams
Comments are closed.
What do you think?To leave a comment, you can:
NFL News
Delivered to your inbox
You'll also receive Yardbarker's daily Top 10, featuring the best sports stories from around the web. Customize your newsletter to get articles on your favorite sports and teams. And the best part? It's free!
Follow us on Twitter
|Latest Rumors
|Best of Yardbarker
Youth Football Referee Wins $275K Settlement After Being Attacked By Irate Coaches And Parents During Game
Today's Best Stuff
For Bloggers
Join the Yardbarker Network for more promotion, traffic, and money.
Company Info
What is Yardbarker?
Yardbarker is the largest network of sports blogs and pro athlete blogs on the web. This site is the hub of the Yardbarker Network, where our editors and algorithms curate the best sports content from our network and beyond.


text:
Community college sets up dates for bond-measure forums
Clackamas Community College has scheduled three public bond forums in May to share information about a potential $90 million bond measure and seek input on the final proposal.
In all, six forums are planned, two at each of the colleges campuses:Oregon City Campus,
Community Center
19600 Molalla Ave, Oregon City
5-7 p.m. Thursday, May 1, and 7:30-9:30 a.m. Friday, May 2Harmony Community
Campus - lobby
7738 S.E. Harmony Road,
5-7 p.m. Thursday, May 15, and 7:30-9:30 a.m. Friday, May 16Wilsonville Campus - lobby
29353 S.W. Town Center Loop E, Wilsonville
5-7 p.m. Thursday, May 22, and 7:30-9:30 a.m. Friday, May 23
The CCC Board of Education is expected to finalize the measure and vote to send it to the Nov. 4 ballot at the July 30 board meeting.
The bond proposal would include projects that were identified as priorities in the colleges Imagine Clackamas community engagement process. More than 2,000 students, community members and staff participated in forums and surveys. Their input showed a high level of support for projects that would update and modernize CCC facilities and increase local access to affordable education and job training programs.
The goals of a bond proposal are to expand training and educational opportunities for students to allow them to transfer to four-year programs or obtain family-wage jobs and to contribute to the local economy by offering more programs that fill work-force needs in high-demand fields.
The proposed bond projects likely would include constructing an industrial technical learning center for such fields as electronics, automotive, manufacturing and welding; modernizing equipment for training in high-demand health care, science and engineering careers; making improvements to existing facilities; and replacing the aging building at the Harmony Community Campus.
The estimated tax rate of the $90 million bond is expected to maintain the current $.19 per $1,000 currently paid by taxpayers.Add a comment


text:
Maroma Maduro Cigars Description
Maroma Maduro cigars are a mellow, aromatic handmade selection created by Nestor Plasencia with a rich-tasting Nicaraguan & Honduran Cuban sandwich tobacco blend. The Maduro boasts toothy Connecticut Broadleaf wrappers that are dark, shimmery, and sweet. Each cigar draws easily, offering you a toasty, well-balanced smoke laced with hints of earthiness, cedar and cocoa. Maroma goes great with a cup of coffee, too. New and budget-minded cigar smokers, take note of this incredible value.
Buy Maroma Maduro Cigars online at discount prices here at Famous Smoke Shop - your source for Maroma Maduro Cigars.
Other Brands by Maroma
Maroma Maduro Cigars Reviews
- San Lotano Habano
- Isla Del Sol
- Padron 1964 Anniversary Maduro
- 262 Allegiance
- Cuesta Rey Centro Fino
- Ashton Estate Sun Grown
- Joya De Nicaragua Antano 1970
- Gran Habano Azteca
- J Fuego Gran Reserva Corojo
- Ashton Small Cigars Connecticut
- Perdomo Habano Connecticut
- Baccarat
- Gran Habano 'Triple'
- Jameson Black Label


text:
I could be doing a multitude of things. Cleaning my room. Taking the kids on the bike ride they've been begging to go on. Clearing my island so it looks like an island instead of the start of what promises to be an impressive hoarder house.
Instead I'm sitting here updating my facebook status 100 times, finally deciding I may as well just blog. It's time for my every-second-month post anyway.
Jordan just left to go to a corn maze with a very good friend and her parents. It's strange having someone call here to snatch a kid for the day. It's stranger still to have my daughter have her own social life. Although I must say, that she does seem to gravitate towards very nice girls, and I hope she continues to seek out such friendships as she moves through her child/teenager years. Next year she'll be in middle school. It would be nicer to see her surround herself with niceness than bitchiness and drama.
This morning I told her she should take a hoodie along, being that they are going to stretch the day into the evening with a bonfire and wiener roast. She disappeared into her room for a minute before coming back into the bathroom to interrupt my tooth brushing. Someone always has a question when I'm brushing my teeth. "Where is my purple sweater?" she asked. I groaned inwardly. "Which one?" "You know," she said. "The purple one with the diamonds up here?" Sigh. "Jordan, we threw that out." A look of horror ensues. "You were with me!" I insisted. She was actually, there was much crying that day. "It was too small for you, and we weren't going to save it for Elliot because you had chewed yourself some thumb holes, remember?" At that point she crumpled to the floor in the bathroom and had a mini-meltdown. I can honestly say I don't think that anything could upset me enough to end up on the bathroom floor. Bathroom floors, no matter how recently cleaned, gross me out. I decided against telling her to get up off the gross bathroom floor, being that it was a time of great sorrow and all. Any hair down there was most likely hers anyway.
I've gone back to substitute teaching, and I must say, I'm really loving it. I think more than I did before. I'm not sure if it's because my kids are a bit older and taking less out of me on a daily basis, or what it is, but I'm loving being back. So much so, actually, that on days I don't get called in the morning I'm kind of in a bad mood about it. I have spent September solely in early and middle years classrooms instead of the much-coveted high school, but that's okay. I've actually come to enjoy the middle years this month. I will say though, still, that I could not do early years. Any time I say that to someone they go on about how sweet they are at that age, love school, blah blah blah. They also cry, and can't tie their shoes, and tattle because someone looked at them funny in the hallway. I honestly just couldn't make a career out of 7 year olds. My kids are used to me and my inability to suck-hole them for things that are kind of stupid. I can't very well tell a classroom full of other peoples little kids to suck it up and knock it off and stop tattling.
The other day a kid held his foot up to me and said "Can you tie my shoe?" and my inner voice said "Are you freakin' kidding me? You're in grade 2, maybe go home and try and learn this, or buy some Velcro." And then I tied his shoe.
In all seriousness though, I give total props to the early years teachers. They have so much work to do. Teaching behaviors, dealing with emotions, taking entire classrooms full of kids who can't read or count, and get them doing both of those things and so much more in a few short years. And not one or two kids either, 26 at a time! It's kind of amazing. I want a high school English classroom someday, and I'm kind of assuming (hoping?) that for the most part the kids will come knowing how to read and we can jump into novel studies after a few classes explaining why "your" does not mean "you are."
Our calendar looks kind of nuts again this year, but in all actuality, we are in less than we were last year. On Mondays the boys swim and Jordan will soon start gymnastics. On Tuesdays, beginning this week I will be starting Zumba! On Wednesdays Elliot has swimming. On Thursdays Jordan and Tennyson have piano lessons and on Saturdays Jordan has swimming lessons and soon the boys will start soccer. I'm happy to have the boys in the same activity at the same time. Makes it nice. I think next time I put the kids in swimming lessons I'll get on it sooner and try and book them all in the same hour. Hopefully. It doesn't always work out all perfectly, but I can hope.
People always look at my with sympathy when I say my kids are in this and that. Honestly, don't. It's a social outing. I visit with other parents, I really enjoy watching the kids do their thing, and it breaks up the week. Watching Jordan smile through the whole gymnastics hour while flipping around the uneven bars and balancing on the balance beam is enjoyable. I like going. If I didn't? We'd be at home. Besides, ducking out with one kid while the husband puts everyone else through the bath and pajama routine has it's perks.
And soccer? I love the soccer season in the spring! We went four nights a week again this last spring, and I like going! We're outside, the kids are running around, they love it, we chat with other parents, we get to be outside when the weather finally decides to be spring-like after a long winter. It's not a chore.
Tennyson and Mitch are both enrolled in Saturday morning soccer all winter. It's an hour at a time and they have actual certified coaches running the program, and it'll be interesting to see if/how they improve over the winter.
Taking them swimming is actually somewhat less enjoyable, but I appreciate that the kids will be less likely to drown if they know how to swim, and they like going, so we go. It's good.
Jordan's not in the play this year, because the organizers were kind of late getting organized and play practice is now the exact same time as the piano lessons our teacher tried so hard to organize around the schedules of all her little students, so we may have to wait until next year. A little sad about that, but sometimes that's life. Next year.
Kind of crazy how they have all decided to suddenly grow up a whole bunch, and become so interested in things, and become good at some things and less interested in others. It's almost like they are real people. Almost. I'd still like to think they are just my little kids.
Tiffany's Spot
Not only is women's work never done, the definition keeps changing . . .
Saturday, September 27
Tuesday, July 15
We went camping this last weekend with Steven's sister Deanne and her husband and boys, and Steven's dad and Step-Mom, and when the weekend was almost over my sister-in-law Deanne pulled out her camera to take a picture of Travis teeter-tottering with the kids and I realized that I haven't taken any camping pictures at all this year, despite this being our third trip, so I grabbed my camera too.
Here is the one lonely camping picture I have taken this year:
I know. You don't have to tell me, I freely admit it: This is some pretty lacklustre photography. It's true.
Today I decided maybe I should finish the post I started weeks ago showing the kids in September, on their first day of school, and again in June, on their last. I plug in the iphone and the digital camera, not sure which device would have the June pictures on it, and what do I find?
My sneaky little stealth photographer has been at it again. Over the years I've downloaded pictures off my camera and found elaborate photography sessions have been held, with little knowledge on my part. Of course, Jordan always puts the camera back where she found it once she's finished taking a hundred pictures of her dolls, siblings, feet, hands, face, the carpet, the dogs, the dogs, the dogs, etc., as well as numerous videos of the other kids doing weird things while she laughs maniacly from behind the camera and tries to direct them.
So, courtesy of Jordan, here are a few camping pictures! I left out the dozen taken of the trees across the road from our site, as well as the ones where she obviously chased an unwilling, grumpy brother around, snapping pictures all the way, and the thousand pictures of each dog.
My favorite is Deanne in her Snuggy. Enjoy!
It's interesting to watch the kids' personalities and interests diverge. Jordan, who came into her own on the field last year decided this year that she was again afraid of the ball, and despite being one of the most energetic kids I know she kind of dawdled around the field, more or less trying to sneakily avoid the action, as opposed to her wicked defense last year, where she was a heck of the obstacle for the other team to get around, with a powerful kick that often sent the ball back into the other end zone. But she had fun, enjoyed being part of the team and spent her fair share of goofing around and heckling other players - mostly those on her own team. Gotta love her.
Tennyson again hit the field with an aggressive determination that any goals scored would be scored by him. Luckily, there were a few other kids who shared the spotlight, and an awesome team of kids who played hard all season. His second last game was a very rainy one and I wore a hat to keep the rain off my glasses. I told him that if he scored three goals I'd throw my hat in. In no time the score was 3-0, and I was momentarily hatless. When the score reached 5-0 I told him he wasn't allowed to score anymore and that he should maybe think about passing the ball to someone else and share the glory. Then he pouted because we cheered like crazy when one of the girls (who had been trying like crazy all season to score) scored and he was convinced we cheered louder for her. Dork. We are going to put him into soccer all this winter (whew, an alternative to hockey) and see how it goes!
Mitchell, who liked to run just fast enough last year to keep him in the very back of the giant clump of running kids decided to run just a little faster this year and do some dribbling and a bit of scoring. We were impressed to see him putting in the effort, considering he's such a laid back little guy. He loves playing soccer, and win or lose, he's pumped to be on the field. He's also excited when it's his turn to sit out so he can hide under the blankets with the other subbed-off kids.
Elliot. This could be its own post. Last year, when she didn't get to play, she whined all spring: "Why not I play soccer? I wanna play soccer." So this year, when it was opened up for four year olds, we signed her up and excitedly waited for her turn.
She played the first game. She played the second. She may have made it part way through the third. Then she decided she wasn't playing. We'd get her all dressed up, head out to the field and tell her to run ahead an join her team. She stood on the field for a few minutes and then came back to where we were sitting.
"I'm not playing."
"What?" I (or Steven) asked. "Why not? Go play soccer! Look! You can do that!"
And she could! She is actually, for a four year old, pretty darn good at grabbing the ball from other kids and buzzing around the field with it, and kicking it at the net where it's supposed to go. But if Elliot doesn't feel like doing something no amount of coercion, threatening, pleading, or getting serious with her is going to work.
"I'm not playing." And off come the shoes, the shin guards, and if she's wearing another shirt underneath, her jersey. Then she runs off to do something else. She doesn't ask either, she just lets us know she's done.
Pretty sure she took a three week break from soccer after the first few games. Often we'd take her and she'd be ten minutes on the field and then just quit. After a while I'd just start asking her before we left the house if she wanted to play. If she said no we just didn't go to her game and instead we all watched Tennyson.
My "favorite" was the time she wore a dress to soccer. We couldn't get her out of the dress, so we brought her jersey, some shorts and her other gear and headed to the field. When the other kids jumped out of the van we stood in front of her and hurriedly said "Here, quick, change into your soccer stuff so you can play soccer! Yay!" and, caught up in the frenzy, she did. Fast forward ten minutes when she realizes what's happened and stomps off the field and stands in front of me with a look that says she won't be argued with and demands: "I want my dress."
"You can't have your dress," I sigh, knowing where this is going.
"I. Want. My. Dress." She says again, louder, slower, a little angrier, because obviously I am not catching on.
"Elliot," I say calmly and sternly, "As soon as soccer is done, I will get your dress for you."
"I WANT MY DRESS!" she hollers.
"Are you going to play soccer?" I ask.
She sits down. Off come her shoes and her shin guards. "I want my dress."
"Alright," I say. "Let's go watch Tennyson."
Tennyson is in another field, and Steven is working an evening service call and I figure that instead of standing on the sidelines and arguing with 40 pounds of brick wall I may as well watch Tennyson (he loves being watched, obviously.)
Elliot, as I am packing up my lawn chair, bug spray, water bottles, and her shoes and shin guards that are scattered in an eight foot radius of where she's standing, realizes that I am no longer paying attention to her needs. She sits down. "I WANT MY DRESS!" she screams.
"Bye Elliot." I turn and leave. She waits until I'm twenty feet away, and then finally gets up and follows at a distance, the entire time wailing "I want my dress!" at the top of her little screechy lungs. Of course on this night Tennyson is playing soccer four fields over, so all the kids and families on the eight other teams we passed got a good earful of wailing, screeching Baby Verwey. It was awesome. Then I get to his field, and organize my lawn chair, bug spray, water bottles, and drop her shoes and shin guards in the grass beside me. She comes and stands against my legs, pressing her little body angrily against mine.
"I want my dress!" She is stuck on repeat. Sigh. Eventually I put her on a dead spot of grass in an empty field and tell her she is in time out and she eventually finishes screaming at me and goes to play with the other soccer players' younger siblings.
Makes me want to rethink her plea to take gymnastics this year.
Anyway. It was a fun season. Lots of fresh air and exercise was had by all!
september and june pictures, 2013/2014, another school year in the books!
Wednesday, June 25
my four year olds
My "baby" is coming up on her fourth birthday. Kind of crazy. Sigh. Anyway, I thought it would be fun to find pictures of each kid at around the same age, so here they are!
Subscribe to: Posts (Atom)


text:
4 tips for wearing neon
Try this homemade juice cleanse
10 motivating tips to get you ready to hit the gym
Memorial Day Weekend style
Best of the Beauty Aisle 2014: Winners revealed
SALE ALERT: New markdowns at Shopbop!
Drugstore beauty buy: Maybelline's latest mascara
Secrets behind a miracle skin ingredient
The hair dryer that will change your life. Really.
Hair trauma? 6 tricks to fix a bad cut or color
Trend to try: A pink trench coat
7 new street style-inspired outfits
Essie's 2014 neon collection is here!
The easiest way to exercise on your summer beach vacation
The surprising thing your feet need for sandal weather
Get ready for bikini season with the beach body burn
Kate Hudson dishes on Ann Taylor's summer collection
A simple breathing exercise that relieves anxiety
A day of sun and surf with Target
The bag worth splurging on
Noonday is finding a way to be fashionable and give back
How to clean makeup brushes and sponges
The perfect sweater for a cool walk on the beach
9 street style outfits to put a spring in your step
7 last minute classic Mother's Day gifts
DIY: Marni-inspired jeweled leather sandals
Pretty, preppy Mother's Day gifts
Six mules not to miss
Brighten up your wardrobe with these colorful bags
Get the look: Sleek and sporty
The latest in fashion, beauty, and hair – delivered straight to your inbox.
Now you can look forward to getting the latest in fashion, hair and beauty delivered straight to your inbox.


text:
In July, Chrome Beta was updated with a new interface that more closely adhered to Google's new design vision - material design. Fitting with Google's occasional habit of stripping things down during major refreshes (see Google Maps on the web), many elements of the interface were sliced, rearranged, or simplified, including the tab indicator in the top right corner of the screen. Previously, the indicator showed users how many tabs were open, but after the redesign it simply displayed a square (or two stacked squares if you had multiple tabs open).
The Play Store has a ton of apps and games, often at very reasonable prices. Still, we live in a world where apps are priced very low, sometimes to the point that people scoff at paying even $0.99 for something. Developers can't just give it away, but they can occasionally drop the price to entice those of you on the fence. So stop with the indecisiveness, and buy some stuff that's on sale.
Today Microsoft is rolling out updates to its OneDrive app across all three of the big mobile platforms: Android, iOS, and Windows Phone. The full list of changes are detailed in the company's blog post, but ironically, Android tops the page with the most new features while Microsoft's own OS is situated at the bottom, not yet equipped with the features that I am about to share.
The Android version of OneDrive is the first to let people import both a personal and work account.
Auto insurance is a thing, and OBD-II diagnostic plugs are also a thing. Metromile brings these two things together in a marvelous fusion of data and pragmatism. With the new Android app, you can get diagnostic data out of your car and take advantage of Metromile's insurance rates based on how much you drive.
Update: A Google representative reached out to inform us that the bug report feature only appears if your phone is also in developer mode (tap repeatedly on the Build Number in the "About Phone/Tablet" menu). You may need to enable developer mode on Android Wear as well, as one commenter points out.
If you've found a problem with your Android Wear watch, you can now submit a bug to wearable app developers.
Update 8/27/14: The new features are now out of beta and available to everyone, just 5 days after the beta release.
Nova users, there's some good stuff happening in the beta channel, so if you're not already aboard that ship, now's a good time to jump on. Today's beta update is a good example of why: it brings some killer new transition animations and app drawer search for those who just have too many pages of apps to swipe through (*cough* Artem *cough*).
Google's official Glassware selection has a new member today - Pandora. As Carl Edwards explains in a post to the official Pandora blog, the addition of Pandora to the Glassware page of Google's MyGlass interface is the result of Pandora's semi-annual 72-hour hackathon. "It was such a hit," the blog says, "that we decided to show it to Google."
In keeping with Google's UX vision for Glass, the Pandora app is exceedingly simple.
Soccer app FotMob has accrued millions of downloads over the course of its time in the Play Store, and now the popular program is expanding its reach to Android Wear. Its latest version shrinks scores, plays, and other information down enough to fit comfortably on a tiny smartwatch display.
Developer NorApps has released a video of the new feature in action. The functionality looks pretty straightforward: swipe up and down to see various matches, and swipe to the right on any given game to view more details.
In a move to shamelessly match Google's highly-aggressive Drive storage pricing, cloud drive favorite Dropbox has finally lowered the pricing and upped the storage of its Pro plans on a massive scale: the company is now offering 1TB of storage for $9.99 a month. That's the same price you'll pay for Google Drive, and even less if you opt for the annual subscription, at $99 per year (17% savings).
That's just getting you to put your wallet on the table, though - Dropbox isn't done yet.
Any miniscule tap will wake up an Android Wear watch and make it start doing stuff, and there's no lock screen option built-in. Baby Time was one of the first Wear apps that sought to solve this, but Shower Wear is on another level. It's like the standard Android lock screen, but it's on your watch.
We've been testing Shower Wear recently to see how it works in practice (we listed it in the last Roundup too).