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Mon, Apr 01, 2013
One of the names that is being quietly discussed as a candidate to replace Craig Fuller as president and CEO of AOPA is Joseph Ratzinger ... who the world knows better as now-former Pope Benedict XVI.
Ratzinger recently resigned the Papacy, and is reportedly looking for an organization that could use his skills in his retirement. It was reported that the former Pope holds a private pilot certificate and a helicopter rating, and often flew the papal helo from the Vatican to Castelgandolfo, his summer retreat.
An internal AOPA memo forwarded to ANN points out that Ratzinger has many of the qualities that could make him a viable candidate for the post. "He is a pilot, and he has international credentials that will make him a strong leader for the international chapters we have. And let's face it, he's infallible. Maybe that will finally get Campbell off our backs," the memo says.
ANN Editor-in-Chief Jim Campbell was unavailable for comment.
The memo indicates that the former Pope has not yet been approached about the idea, and admits that they would have to come up with a very attractive package to lure Ratzinger out of retirement. Another memo discusses the possibility of constructing a balcony at AOPA HQ in Fredrick, MD, from which he could address the membership, and muses about a deal with the White House for a time-share agreement for the use of nearby Camp David. "Maybe we can give him a different retreat to fly to," the memo states.
Airborne 11.21.14: AEA's 3Q/14 Report, Fantasy Of Flight, Modernizing The NAS
Aero-TV: Lessons Learned -- Reflecting On Mark Baker's First Year At AOPA
Airborne 11.19.14: FAA v Pirker Update, F-35C Night Traps, G650ER Delivers
See All
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© 2007 - 2014 Web Development & Design by Pauli Systems, LC


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More Labrador Retriever Puppies and Dogs for sale.
LOOKING FOR THAT ONCE IN A LIFE TIM... Fur & Feathers Kennel in Craig, Nebraska
(WI) QAA MH Black Labrador AT STUD... Hunters Kennels in Menasha, Wisconsin
LOOKING FOR A LAB PUP FOR CHRISTMAS? WyngMaster Labradors (Est. January, 2000) in Tulsa, Oklahoma
UT,ID,MT,WA,OR,WY AKC chocolate lab pupp... Snake River Retrievers in Saint Anthony, Idaho
AKC Chocolate & White Labrador Retr... Trinity Kennels in Hubert, North Carolina
AKC Chocolate Lab pups pedigrees LO... Elite Labrador Retrievers in Central Valley, Utah
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AKC STARTED CHOCOLATE & BLACK LABS!... Bird Dog Kennels AKC Started Retrievers in Battle Lake, Minnesota
Sold out chasecollin kennel in Bluff City, Tennessee
Lab Pups Ready Now Spring Creek Kennels in Newtown, Missouri
QAA Sired AKC puppies we have 2 Bla... Hill Top Acres in Harriam , Tennessee
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UPCOMING LITTER DUE JAN. 13TH - THUNDER ... WyngMaster Labradors (Est. January, 2000) in Tulsa, Oklahoma
AKC White Males Ready Now HUNTERS PRIDE LABRADORS in Homer City, Pennsylvania
Young Started Retrievers Available Renegade, LLC in Oxford, New York
AKC Yellow Female 1 year old Hill Top Acres in Harriam , Tennessee
CKC Hunting Bloodline Lab Puppies R... Johnson's Labrador Retrievers in Mount Juliet, Tennessee
AKC Master Hunter And Junior Hunter... Johnson's Labrador Retrievers in Mount Juliet, Tennessee
(WI) Serious Hunters & Competitors ... Hunters Kennels in Menasha, Wisconsin
GRHRCH UH -OAA- MNH Sired Labrador ... Case's Fowl Retriever's in clarksville , Michigan
Chocolate Labs from good hunting backgro... BOPCO kennels in Angleton, Texas
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STARTED YELLOW LAB FEMALE FOR SALE Orion Labradors in Frankfort, Indiana
Black Female Pup, Awesome Pedigree Siedelmann Labs in Audubon, Iowa
QAA MH AKC American Labrador Retriever FEMALE !! 1 LEFT - REDUCED - Labrador Retrievers in Harriam , Tennessee - Hill Top Acres
I have a AKC American Style Labrador Retriever Puppy with a Block head that was born on Dec 11, 2013 that will make outstanding hunting partner and very intelligent puppy. the sire is Troulblesome Falsely Accused QAA MH title and the dame has two passes on her started title she also comes from a service dog.Both dogs have OFA Good and Normal Elbows. Please visit my website to see current pictures of SHELBY and YELLA and there information www.hilltopacres.biz or call for more information All of our puppies come with a 26 month hip warranty and health guarantee. 1 YELLOW FEMALE ($600) Please call at 865-805-4022 or 706-818-4590(cell) 14 WEEKS OLD
Ad location: Harriam , Tennessee
Ad created: Mar 23, 2014
Contact Information
Contact Name: Christy Holbrooks
706-818-4590Contact breeder through email Click here to visit website
Hill Top Acres Breeder Information
My Classified Pictures

subset: commoncrawl


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10 Steps to Pick the Right Doctor
Whether you need a primary care doctor or a specialist, these 10 steps will ensure you find the right doctor for you. View Slideshow
Dr. Sanders' Experience
Research training, expertise and qualifications
- Dermatology
Board Certifications
- Dermatology
Procedures Dr. Sanders Performs
Dr. Sanders does not have any procedures listed. If you are Dr. Sanders and would like to add procedures you perform, please update your free profile.
Conditions Dr. Sanders Treats
Dr. Sanders does not have any conditions listed. If you are Dr. Sanders and would like to add conditions you treat, please update your free profile.
Background Check for Dr. Sanders
Malpractice Claims not available
- Healthgrades does not collect malpractice information for Utah.
- No sanctions history found for the years that Healthgrades collects data.
0 Board Actions
- No board actions found for the years that Healthgrades collects data.
Awards & Recognitions
Education & Training
Medical School
- University Of Utah School Of Medicine
- Graduated in 1982
Internship Hospital
- Lds Hospital
- Complete in 1983
Residency Hospital
- Mayo Grad School Med/Mayo Fndn
- Complete in 1987
Languages Spoken by Dr. Sanders & Staff
- English
- Spanish


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- Freeport murder suspect Damon Dixson taken into custody in Rockford
- Local gas station employee arrested for selling liquor to minor
- Renewable Fuel Standard delay 'a mixed blessing,' Bustos says
- Rockford delegation presents inaugural 'Rockford Award' to Norwegian Air
- Education in Illinois making slow progress, according to report
- Illinois GOP Congressional delegation: Obama's immigration plan undermines rule of law
- Suspect, 17, charged in Halloween hit-and-run in Roscoe
- Saint Anthony College of Nursing president to retire
- Man found guilty in deadly August 2013 crash at Mulford and Garrett Lane
- 'The Price is Right Live!' at Coronado March 1; tickets on sale Nov. 21
Housing market still slumping in Illinois
By Andrew Thomason
Illinois Statehouse News
SPRINGFIELD, Ill. — The scenery on a walk through the neighborhoods surrounding Illinois' Capitol building is filled with signs of a sagging housing market.
On nearly every block, a house has a "For Sale" sign, weathered and worn from the long period of time it's been in the elements, or a house has deteriorated, because the homeowner, unable to make their mortgage payment, abandoned it.
As Illinois' housing market continues to struggle, it weighs down the state's economy and exacerbates a high unemployment rate, according to the July 2011 Monthly Briefing report released this week by the Commission on Government Forecasting and Accountability (COGFA), a bipartisan research arm of the Legislature.
The number of new, single-family housing permits for June — 680 — saw a 14.9 percent decline, or 120 fewer, compared with June 2010, according to the report. Single-family housing permits have seen minuscule fluctuations during the past three years, but have been stagnant more or less since dropping dramatically after the housing bubble burst in 2008.
"Builders are not building because of this oversupply of not only new homes that are on the market, but all these foreclosures and short-sales banks are doing and et cetera," said Edward Boss Jr., COGFA's chief economist and author of the report.
The housing market affects the state's economy by adding construction jobs that lower the unemployment rate, and increasing sales in ancillary consumer goods associated with houses, said Geoffrey Hewings, a professor of economics and urban and regional planning at University of Illinois at Urbana-Champaign.
However, people should not expect this economic boost anytime soon, as the national and global economies flounder and potential homebuyers hesitate to take on this financial albatross, Hewings added.
"It's just very uncertain times, and this is not the time a lot of people feel comfortable about going out and making a commitment on a home," Boss said. "Not only may the price be lower a year from now, but you may not have a job."
Another factor playing into the housing market melancholy is the end of a stimulus program that gave federal tax credits to first-time homebuyers, said Mary Schaefer, a spokesman for the Illinois Association of Realtors, a trade association for Realtors in the state.
Additionally, home sales in the years leading up to the 2008 crash were likely artificially inflated because of lending practices where people were given mortgages on homes without having to make much, if any, of a down payment, Boss said.
At least one program in Illinois is looking to push the housing market upward, though how successful it will be is questionable.
The Illinois Housing Development Authority, a self-sustaining entity that runs off tax-exempt bonds, announced this week it will offer up to $200 million in low-interest rate mortgages to about 1,300 low- to moderate-income homebuyers. The homebuyers' payments on these mortgages are used to pay for the bonds.
In addition to the 30-year mortgage, some people could qualify for up to $6,000 to help with a down payment on their new home in the form of a zero-interest, 10-year loan.
The authority said it's not creating a mini-housing crisis by lending money to the same demographic of people that was a major player in the national housing crisis.
"The program creates safe and responsible homeownership opportunities," said Rebecca Boykin, a spokesman for the authority. "Our program requires homeownership counseling … as part of the qualification process."
Beyond homeownership counseling, participants must have a minimum credit score of 660 and contribute 1 percent or $1,000 of the purchase price, whichever is greater, toward the down payment.
Hewings said no matter what, risks are associated with this and other similar programs.
"These folks may not have the capacity even with these incentives … to sustain their payments," Hewings said.


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I would quite like to own a phone with it, and the Hermes DOES have it.
Hermes also has a 2MP camera...
Breeze has little noticeable improvement but also microSD.
P (still despairing!)
Jump to content
You can follow me on Twitter - http://twitter.com/paulobrien / Follow MoDaCo on Twitter - http://twitter.com/modaco
Want to donate? MoDaCo is raising money for the Multiple Sclerosis society.
Why HTC seem to have chosen leetspeak to brand their deivces is beyond me. Maybe they're trying to appeal to a yonger audience? Let's just hope the likes of Orange and O2 don't follow suit. That would not be teh r0x0r (whatever that means)
This is all quite sad
HTC really need to get on the ball and produce up to date products matching their opponents, such as Nokia.
If they released a Symbian phone with those specs, they wouldn't sell more than a couple of units. I like the WM platform but this only stretches so far before all the other benefits of phones on other platforms sway me.
I still exist
0 members, 0 guests, 0 anonymous users


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Heat Hotel
Heat Hotel in Lake Havasu City
Heat Hotel
Hotel Guest Rating: 7.2/10
1420 Mcculloch Boulevard North
Lake Havasu City, AZ 86403
Welcome to the Heat Hotel
A waterfront setting with views of the original London Bridge, contemporary rooms and a vibrant patio bar are the highlights of a stay at the hip Heat Hotel in Lake Havasu.
Hotel Features
At the boutique-style Heat Hotel, 25 rooms and suites boast contemporary furnishings and spectacular views from private balconies. Amenities include pillowtop beds with high-thread-count linens, as well as microwaves, mini-fridges and flat-panel cable TVs. Select suites also feature jetted tubs and huge showers. But the real draw is the 4,000-square-foot patio bar and lounge where guests can tie up their boats and kick back with a frosty drink on a daybed or in private cabana. There's free Wi-Fi access throughout the hotel.
Hotel Location
The Heat Hotel is on Thompson Bay in Lake Havasu City. London Bridge and the Convention and Visitors Bureau are less than a mile away. Also nearby is the scenic shoreline of Lake Havasu State Park, a hotbed for water sports, with beaches, picnic areas and boat ramps. Nature lovers can trek the mile-long Mohave Sunset Trail along the shoreline or visit the Arroyo-Camino Interpretive Garden showcasing the park's biodiversity. Lake Havasu City Airport is about seven miles away, and McCarran International in Las Vegas is 152 miles from the hotel.
Guest Favorites
"Modern, classy rooms" with "balconies facing the river and London Bridge" are some of the big draws for Priceline guests, who also like the "excellent location" of the Heat Hotel.
Heat Hotel Amenities
- 24-hour front desk
- Air conditioning
- Air conditioning individually controlled in room
- Alarm clock
- Banquet facilities
- Cable television
- Direct dial telephone
- Elevators
- Free local calls
- Free parking
- Hairdryer
- Handicap rooms
- High speed wireless
- Housekeeping - daily
- Interior corridors
- Iron
- Ironing board
- Private bath or shower
- Remote control television
- Wireless internet connection
Hotel Information
Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges.Guests under the age of 21 are only allowed to check in with a parent or official guardian.Please note: Guests are advised that every Friday and Saturday, from March through October, there is a DJ that plays until 2am in the bar. Some noise may be heard in the guest rooms. Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.
Hotel Guest Reviews of the Heat HotelOur hotel ratings and reviews are from real hotel guests. Priceline.com ensures that its reviews are guests-only by proactively sending hotel surveys to customers after they've completed their hotel stays. In the post-stay surveys, priceline.com hotel customers are asked a number of questions about their stay and the hotel. On a scale of 1-10 with 10 being the best, the survey asks guests to rate their overall experience and specifically rate the hotel's cleanliness, staff and location. Priceline.com does not allow site visitors to post unsolicited hotel reviews.
November 11, 2014
November 10, 2014
No eating amenities at the hotel but a good variety within short walking distance.
November 1, 2014
The rooms are awesome!!! I could see it being very noisy in the peak season with the outdoor bar right outside, wouldn't bother me but people with children or elderly people not liking it! Other than that wonderful!
October 28, 2014
Family Traveling with Teens
July 18, 2014
I liked the room layout and location near a lot of activity. Good view. Only negative is that the hotel's carpet and furniture are run down slightly.
June 3, 2014
Would have been a great hotel if it weren't for the ridiculously loud music from the club. I was expecting some music,at the lake, but the bass literally shook the whole hotel. There were only four or five people at the club from 1200 til 200 in the morning but there was no break in the jams! Will not stay there again
April 15, 2014
This guest did not leave comments about this hotel.
February 25, 2014
I would definitely refer friends to visit this Hotel. It was nice and had a great location.
January 26, 2014
Would love to return during spring break!
January 19, 2014
Location of our room right on the water was great (Inferno 06) - Convenient to walk and physically close to our activities, but VERY DIFFICULT to drive in and out of due to no traffic signals and lots of cross-traffic - very frustrating and time-consuming to deal with
(1 - 10 of 20 reviews)
- Bridgewater Motel from $56 (0.2mi)
- Island Inn Hotel from $59 (0.3mi)
- London Bridge Resort from $109 (0.3mi)
- Motel 6 Lake Havasu City - Lakeside from $40 (0.3mi)
- Bella Soleil By Destination Havasu from $375 (0.5mi)
- Ed's Deli (1.1mi)


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Logical Fallacies IIA particular tribe has two categories of tribesmen: Sunkind and Moonkind.
When asked a question by an outsider, a Sunkind will always answer truthfully, whereas a Moonkind's answer will always be false. Apart from that, members of the two tribes are virtually indistinguishable, as they dress and behave identically.
You've just met two tribesmen at a fork in the road. You have a hunch that the first is a Sunkind and the second is a Moonkind, but you haven't confirmed it.
So you point at the first tribesman and ask: "Are you a Sunkind or a Moonkind?"
"I'm a Sunkind," he replies. Which is exactly how a Sunkind would answer that question.
Then you point at the second tribesman and ask the same question.
His answer: "I'm a Sunkind." Which is exactly the answer a Moonkind would give.
You take these answers as proof that the first tribesman is a Sunkind, and the second is a Moonkind.
Is this wise?
Logical FallaciesA particular tribe has two categories of tribesmen: Sunkind and Moonkind.
When asked a question by an outsider, a Sunkind will always answer truthfully, whereas a Moonkind's answer will always be false.
One day, you happen upon a member of the tribe at a fork in the road. You're sure he's either a Sunkind or a Moonkind, but you have no idea which one.
So you ask him: "Excuse me, sir. Are you a Sunkind or a Moonkind?"
"I'm a Sunkind," he replies.
What have you proven?
Character profile: Kara"The sun rises in the east and sets in the west. Gravity pulls all objects downwards, but there are methods of resisting it. A snake is a reptilian creature that does not have legs. Electronics will only work when plugged in, unless they have batteries. There is no such thing as a god or goddess. Such simple and infallible facts should always be kept to heart by an explorer such as myself." --Kara
Type of character: Sonicverse - Aganre sub-verse
Name: Kara Zinaksa
Age: About 25
Gender: F
Race/species: Spectacled cobra (Mobian, Aganre-style)
Occupation: Explorer
Weapon of choice: Crossbow w. sniper scope
Family and associates:
Eldest of four siblings. Single; has not yet been selected for a Test of the Gods.
Kara has the typical Aganre body and build. Her primary body color is a light yellow (FFFF00 in standar
Cartoon BullfightingBullfighting in cartoon worlds is significantly different from real-world bullfighting, owing mainly to the fact that the bulls are just as sapient as the fighters.
Cartoon bullfighting is more like a cross between normal bullfighting and prizefighting. It's a duel between a heavyweight (the bull) and a lightweight (the bullfighter) in a large, circular dirt arena, where the bullfighter attempts to use wits and agility to defeat the bull, who attempts to use its sheer brawn to defeat the bullfighter. The first to flatten or otherwise incapacitate the other party wins the round; whoever wins two out of three rounds wins the match.
Even after one participant has won the round, they are given extra time to play with their conquered opponent to humiliate them further (and entertain the audience even more). Then the fighters are allowed an intermission to rest up and recover. At the end of the match, the winner and loser are each given a quick 30-second interview fro
Character profile: Starke -Gift-"Good to see you again, mate. I was hoping-- WHAT DID YOU JUST CALL ME?! GET OVER HERE! *GRAB* *SQUISH* Hmm... I'm in the mood for soccer tonight." --Starke
Type of character: Cartoon 'verse
Name: Starke (pronounced "stark")
Age: Unknown - seems to be in his 20's or 30's
Gender: M
Race/species: Werewolf (anthro); believed to be part kangaroo, but this is unconfirmed
Family: No known relatives.
Starke has an intimidating werewolf build, quite muscular and about a head taller than most anthros. He typically stands slightly hunched over. His primary body color is moderate gray, about A0A0A0 in RRGGBB hexadecimal; his muzzle and chest are a lighter gray with a hint of blue (AFB3D0). He has a section of longer spiky fur on his head that serves as hair; this area is a darker gray (707070).
Bookwolf -Trade-Wolfen Down took a deep breath as he sat at one of the tables in the library's reading area. The lead he'd come to the city to pursue had turned out to be a bust, so here he was, hoping to kill time until Hisspan arrived to rendezvous with him.
The wolf set the book he'd picked out in front of him. The title "PHOENIX" graced the front cover. According to the jacket, the book told the story of a Mobian phoenix with a shattered memory. The phoenix could remember that his name was Tip and that he was the prince of somewhere, but that was it. He toured the galaxies by whatever means he could, searching for clues about his identity. Wolfen had picked out the book because Tip's situation was so similar to his own.
Maybe I'm the prince of some kingdom somewhere and I just don't know it. But then Havoc would probably have told me by now... oh well, let's get started.
He started reading.
The story opened in a spaceport called St. Nebula. &
What Makes a Fish a Fish?(Written by Anya Marasaka during a spell of boredom)
What makes a fish a fish?
There are many different types of fish, of all shapes and sizes. But they are all, undoubtedly, fish.
The main defining characteristic of a fish is that it lives in the water, but is that enough to go by?
There are birds that cannot fly, and mammals that lay eggs. And there are creatures which dwell in the water but are not fish.
If a fish were to dwell on land and breathe air like we do, would it still be able to classify itself as a fish? If so, then why?
Where can the border between "fish" and "not fish" be found?
There are so many categories in the world that we take for granted, but that are impossible to explain simply without contradiction.
If, tomorrow, I were to meet a creature that naturally walked on legs and did not inject venom nor constrict, yet still called itself a snake...
...how willing would I be to believe it?
Character profile: Pya"Unworthy? Don't be ridiculous. Worthiness is just a delusion. An ambassador like myself should never consider herself too important to spend time with the lower class." --Pya
Type of character: Sonicverse - Aganre sub-verse
Name: Pya Sosori (PIE-uh suh-SOH-ree)
Age: Around 30
Gender: F
Race/species: Ball python (Mobian, Aganre-style)
Occupation: Tribe ambassador
Weapon of choice: Sai
Family and associates:
Middle of three siblings. Married to Tanjo Sosori (king cobra), the tribe's chieftain. Has four children.
Pya has the typical Aganre build. Her eyes are blue. Her main body is solid black, but her underbelly is white, and her black areas are covered in large, chocolate brown blotches of varying shapes. Two vertical stripes of the same brown cover the top of her head.
As the tribe's ambassador, she dresses a bit more fancily than a commoner would. Sh
relying on your profession to make you bravethirty-six hour days and poorly brewed, gelatinous coffee pooling in your belly does not mean that you are a poet. the act of pulling on gloves and pressing your hands into a cold, stiffening cadaver does not mean that you are closer to god and therefore more capable of reaching others with your words. all it means is that you're dog tired, your eyes are red raw from over-blinking and your slim, pretty hands are shaking around that discoloured lung as you struggle to push vomit back down your throat; it means that, when you get home and tear out your notebook in a rush driven by sleep deprivation, you're nonsensical; it means that, when i stumble into bed at night and think of the words i've read today, i don't think about yours because they're as empty of life as the silent cadavers you tear apart. and i don't know about you, but none of that sounds particularly grandiose or poetic to me.
Writing Practice: Five Senses--Kenneth Young
What does Kenneth SOUND like?
Kenneth has a very down-to-Earth, informal way of speaking most of the time, even when he's trying to be serious, and has sort of a goofy, self-deprecating sense of humor. Though you would expect his voice to be deep and Schwarzenegger-like thanks to his huge musculature, he's actually more in the middle, though his voice gets a bit higher when he's over-excited or nervous. He also has an infectious and almost awkward-sounding laugh. It's actually been really difficult pinning down the perfect voice actor for Kenneth, though; I've junked at least 4 people who I've considered over the years. But I guess to give kind of an idea of his voice, I'd go with Chris Pratt for now, or Nathan Fillion as someone helpfully suggested.
What does Kenneth SMELL like?
Kenneth's smell is usually a combination of three things: Pert 2 in 1 Shampoo and Conditioner, Irish Spring bar soap, and either Right Guard
When The Cat KnocksWelcome back – please, sit down, take the weight off your feet, have some tea. I was just having a conversation with an old friend, and fixing up to call on her in her home at some point.
I guess that's one of the reasons I like to do home visits for security consultations and the like – I want to meet people and help them, as opposed to my younger days, when I wanted to meet people and take their valuables. That did not mean I did not get to know them as well – take, for example, the Chelsea housewife I met in the early eighties.
It was at the height of the Sloane ranger movement, and this particular ground floor flat belonged to a scion of that movement. She was in her PR job that morning, so I decided to break in and relieve her debt burden somewhat. Entering the flat was easy enough, as I slipped into the front door as someone else came out, and then picked the lock.
What I had not figured on was the fact she was a bit more organised
Perfect PearAt long last I found them. The one set of clothes I'd been dreaming of. Since coming to terms with my...sexuality, and discovering the existence of such a wardrobe, I've wanted them. After saving up for years and searching through every online enchanted clothing store, I was at long last able to buy my own. After two weeks, they arrived at my front door.
Tearing off the packaging, I laid out the fitted white long-sleeve t-shirt and snug black leggings on the bed. Eager to get started, I read over the instructions:
"Slip on the clothing, making sure everything is adjusted correctly. The clothes will shape themselves to your frame and grow as you do. As with all weight gain, you must eat for it to occur. Even small snacks will cause growth, but for best results consume large amounts. The more you wear the clothes, the more you will grow. Any and all weight gain achieved with these enchanted garments cannot be reversed by any means (including magic), so be sure this is the right path for
Family games timeYeah, Steve told me about what he did that afternoon, and it made me think about one of the visits I'd made before we headed over here. I'd picked up a few things about planning from him, and this particular home near me had caught my eye a few weeks ago, when I saw the mum bringing in some very expensive looking items from her car.
I found out she ran a fashion boutique in town, and she lived with her eleven and ten year old daughters – no man about the house, which was a help to someone like me. So I decided to pay them a visit on the Sunday before we flew out. I spent the time learning their names – the mum was Tammy, and her daughters Nikki and Anna.
So I drove round to their house on the Sunday, parking my car a few streets away and walking along the street. I had a black leather biker's jacket over a roll neck sweater, tight leggings and knee length leather boots, with a small grey rucksack on my back, containing everything I
Little John I walked in the door and immediately was tackled by my nieces and nephew. "Uncle Johnny, Uncle Johnny!" they were all shouting. I picked up the little girls and marched into the house, plopping down on the couch as they proceeded to show me their hair, dollies, and the kitchen play set they had in the corner.
"Johnny?" My nephew Stanley asked, "can we play with your doggy again? You promised!"
My sister Christine walked into the room. "John, you'd better not!"
"Mommy, please?" Stanley asked. "I wanna see the doggy!"
"Yeah," Alissa, the older niece, said, "We could take care of a doggy for a little bit."
"Yeah, Mommy please?" Stanley asked. "Can we have a doggy play with us tonight? Please!"
Autumn DayShe lounged fireside beneath her favorite throw, basking in the birth of autumn. Raising a glass of warm cider to her lips, she sighed and lazily reached to scratch her tabby cat beneath the chin. "It's a good day to read, isn't it?" she said. He blinked slowly and purred back at her. "I thought so." She took another sip of cider and opened her book to the familiar scent of crisp paper and the anticipation of another page.
14. and 15.I.
There was a woman, the Last Woman. She and her companion, a man, were the final representatives of humankind. Like all things, humankind must end—and end it would, soon, when the two succumbed to the ravages of the sickness their species, in their desire to destroy, had unleashed upon itself. She thought of her death, and she wept. The man asked why, and the woman answered: For this! This legacy of death! This fate which our ancestors wrought upon themselves and upon us! The man sat beside her, held her, and began to weep too. And weeping, they died.
There was a woman, the First Woman. She and her companion, a man, had been created as perfect examples of their kind. And perfect examples they were—in their imperfection. Cursed with death for their sins, they now approached their end. But humankind had spread and would continue, spreading also violence, jealousy, hatred, death. The woman considered this and wept. The man asked why, and she answered: For this! This lega
|Sta.sh Submit


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The United States women's basketball team dominated the Beijing Games, winning by close to 38 points per game while cruising to the gold medal.
LAS VEGAS (AP) - Anthony Davis was seated on the court, the best players in the world towering above him.
LEOMINSTER, Mass. (AP) - A Massachusetts police officer is under investigation by his own department after allegations surfaced that he directed a racial slur at Boston Red Sox outfielder Carl Crawford last week.
SAN FRANCISCO (AP) - Investigators say there is not enough evidence to arrest San Francisco Giants slugger Pablo Sandoval for an alleged sexual assault at a hotel near Santa Cruz.
PHILADELPHIA (AP) - Joe Paterno and other top Penn State officials buried child sexual abuse allegations against Jerry Sandusky more than a decade ago to avoid bad publicity, according to a scathing report Thursday that exposed a powerful "culture of reverence" for the football program and portrayed the Hall of Fame coach as more deeply involved in the scandal than previously thought.
HAVANA, Ill. (AP) - As scientists aboard a research boat activate an electric current, the calm Illinois River transforms into a roiling, silvery mass. Asian carp by the dozen hurtle from the water as if shot from a gun, soaring in graceful arcs before plunging beneath the surface with splashes resembling tiny geysers.
AUSTIN, Texas - In a letter to federal authorities, a Wisconsin congressman equates the anti-doping charges against Lance Armstrong to a conspiracy theory and calls the U.S. Anti-Doping Agency's authority over the seven-time Tour de France winner "strained at best."
ORLANDO, Fla. (AP) - Magic general manager Rob Hennigan said Wednesday that trade talks involving Dwight Howard with the Brooklyn Nets are "stationary," but that discussions remain open with them and other teams.
NEW ORLEANS (AP) - Drew Brees and the New Orleans Saints still must close a significant gap in guaranteed money if they are to agree on a five-year contract worth about $100 million by Monday's looming deadline for a long-term deal, said a person familiar with the negotiations.
KANSAS CITY, Mo. (AP) - Chipper Jones made a brand new stop on his farewell tour.
KANSAS CITY, Mo. (AP) - Justin Verlander wanted to give the fans an All-Star show.
KANSAS CITY, Mo. (AP) - Ryan Braun was back in the spotlight at the All-Star game. And this time, it was for what happened on the field.
KANSAS CITY, Mo. (AP) - Melky Cabrera and Pablo Sandoval sent the National League to a big early lead. Matt Cain and the rest of an imposing pitching staff finished off a Giant blowout in the All-Star game.
MIAMI (AP) - Rashard Lewis has decided to join the Miami Heat, becoming yet another shooting option for the reigning NBA champions.
Things to watch in Week 12 of the Big 12 Conference season, when league co-leaders Baylor and Kansas State are among the four teams not playing:
Oregon jumped undefeated Florida State and moved into second in the College Football Playoff rankings while TCU took over the fourth spot Tuesday night.
KANSAS CITY, Mo. (AP) - The Chiefs have promoted running back Charcandrick West from the practice squad and signed tight end Phillip Supernaw after losing Cyrus Gray and Demetrius Harris to season-ending injuries.
KANSAS CITY, Mo. (AP) - After getting trounced by Tennessee in their season opener, the Kansas City Chiefs returned to their practice facility the following day and went through the game film in all its gory detail.
Two weeks ago, West Virginia coach Dana Holgorsen starting preparing for a Baylor team that was coming off a wild comeback win over TCU.


text:
Winnipeg Free Press - PRINT EDITION
Leos avenge season-opening loss to Stamps
Clubs tied for second in west
VANCOUVER -- Tim Brown returned a kick-off 97 yards for a touchdown and Andrew Harris scored on a 40-yard passing play as the B.C. Lions beat the Calgary Stampeders 26-22 in CFL action Saturday night.
Backup quarterback Thomas DeMarco also scored a touchdown for B.C. as the Lions improved to 5-2 and moved into a tie for second place with the Stampeders, who are also 5-2.
B.C. avenged a one-sided season-opening loss to the Stampeders and ended their winning streak at four games.
The Lions earned their remaining points from a Paul McCallum field goal, three converts and a late safety conceded by Calgary.
Jon Cornish and Marquay McDaniel scored touchdowns for Calgary, while Rene Paredes furnished two field goals and a pair of converts. B.C. also surrendered a safety.
The Lions, who have had trouble scoring in the first quarter this season, got off to a quick start as Harris caught a short pass from Travis Lulay and scampered into the end zone from 40 yards out on B.C.'s first drive.
Cornish enabled the Stampeders to draw even as he bulldozed two yards into the end zone late in the first quarter.
But B.C. quickly took the lead again, returning Paredes' ensuing kick-off 97 yards for a touchdown. Parades had a chance to tackle Brown near the sideline, but he turned away and did not make contact while Brown twisted in the opposite direction and angled his way into the end zone.
A safety conceded by McCallum helped the Stampeders reduce their deficit to 14-9. Calgary took a 16-14 lead midway through the second quarter after Kevin Glenn connected with Marquay McDaniel on a 14-yard touchdown pass.
But a rare miscue by Cornish enabled the Lions to take a 21-14 lead. After catching a Glenn pass, Cornish was hit hard by B.C. nickelback Korey Banks and the ball popped into the handles of linebacker Adam Bighill.
Although the ball did not hit the ground, it was ruled as a fumble, with Banks credited for the force.
B.C. got the ball on Calgary's 28-yard line. Four plays later, backup quarterback Thomas DeMarco plunged across the goal-line. The touchdown came after a pass interference penalty on Calgary's Chris Randle, who tugged on Emmanuel Arceneaux in the end zone, giving B.C. the ball at the Stampeders one-yard line.
Lulay launched a hail-Mary pass on the final play of the second quarter in an attempt to produce another B.C. touchdown. But Randle intercepted the pass to ensure the Stampeders still trailed by only seven points at half-time.
The Lions' defence entered the game with a clear mission to stop Cornish, and held Calgary's star running back to 73 rushing yards and a touchdown, one week after the Canadian scored four TD's in the Stampeders game against Saskatchewan.
Lulay completed 16 of 28 passes for 223 yards while Glenn was good on 22 of 38 pass attempts for 199 yards.
Calgary reduced its deficit to 21-19 early in the third quarter on a 32-yard Paredes field goal. But the Lions went up 24-19 on McCallum's 24-yard field goal early in the fourth quarter.
The Stamps pulled off some subterfuge, faking a punt with just over five minutes left in regulation time. A 30-yard field goal pulled them within two points.
With just under two and half minutes remaining, the Lions tried some razzle-dazzle of their own that backfired on them -- but not for long. Harris took a hand-off from Lulay and pitched the ball back to the QB, but he was forced to scramble and Jamar Wall intercepted the underthrown pass intended for Courtney Taylor near Calgary's goal-line.
However, B.C.'s defence held the Stampeders in check as Glenn failed to complete two passes, and Maver conceded a safety instead of attempting a punt out of the end zone.
But the Lions did not gain any traction following Calgary's kick-off and were forced to punt with 1:11, setting the stage for a frantic finish.
-- The Canadian Press
Republished from the Winnipeg Free Press print edition August 18, 2013 B2
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- Five storylines
- Elimimian named CFL's outstanding player, top defensive performer
- CFL picks
- Hickman, Ticat D-line hold key to cup
- Stampeders sophomore centre Jones named CFL's top lineman award winner
- McCoy, Eagles dominate Cowboys 33-10, might have to beat them again to get back to playoffs
- Ravens wide receiver Steve Smith says Panthers 'stabbed him in the back' when releasing him
- Ray Rice wins appeal; NFL suspension vacated immediately because of 'arbitrary' decision
- 49ers' offence falls flat in 19-3 loss to Seahawks in NFC West rivalry
- Stampeders coach Hufnagel OK with players having sex before Grey Cup
- Every scream is for his team
- Bisons face great unknown
- Jim Lawson not interested in CFL commissioner's seat
- Blue lock up veteran defender
- Brandon Banks returns two punts for TDs to lead Ticats back to Grey Cup
- Hamilton Tiger-Cats and Calgary Stampeders set to meet at Grey Cup in Vancouver
- Stamps won't even have to work up a sweat
- Bisons go down battling
- Blue need some free-agent scores
- Lions extend three Canadians, including defensive tackle Westerman
- Blue Bombers start ticket renewals, embrace beer snake for 2015
- Win in finale cold comfort for Bombers
- Blue need a ton of repairs
- Will next CFL commissioner be a Winnipegger?
- O'Shea knows Bombers job under review
- Blue need some free-agent scores
- Receiver position will complete your Bomber choices
- Attention O'Shea: Fire Etcheverry
- Blue not wise to put all their eggs in Willy's basket
- O'Shea thinks Drew Willy should be MOP
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Publications (11)59.47 Total impact
Article: An open-label, pilot study of fludarabine, cyclophosphamide, and alemtuzumab in relapsed/refractory patients with B-cell chronic lymphocytic leukemia.[Show abstract] [Hide abstract]
ABSTRACT: Although combination regimens have improved outcomes over monotherapy in chronic lymphocytic leukemia (CLL), patients eventually relapse. Combined fludarabine, cyclophosphamide, and monoclonal anti-CD52 antibody alemtuzumab (FCC) provided synergistic cytotoxicity with effective clearing of minimal residual disease. This phase 2 study determined FCC efficacy and safety in relapsed/refractory CD52(+) B-CLL after ≥ 1 line of treatment. From January 2005 through June 2008, up to 6 courses of oral fludarabine 40 mg/m² per day, oral cyclophosphamide 250 mg/m² per day, and subcutaneous alemtuzumab (Mab-Campath) 10 mg (increased to 20 mg after first 10-patient cohort) were administered days 1 to 3 every 28 days. The primary objective was overall response rate (ORR); secondary objectives included response duration, time to disease progression, and safety and tolerability. ORR was 67% in 43 patients; 30% achieved complete response. ORR significantly improved with 1 versus ≥ 2 prior therapies (P = .018), and without versus with previous monoclonal antibody treatment (P = .003). Median progression-free survival was 24.4 months, not reached in patients achieving complete response. Median overall survival was 33.6 months. Myelosuppression was the most common adverse event, with a low percentage of cytomegalovirus reactivations and manageable infections. However, close vigilance of opportunistic infections is warranted. FCC provides effective immunotherapy in relapsed/refractory CLL, including in patients with poor-risk prognostic factors.Blood 07/2011; 118(15):4079-85. · 9.78 Impact Factor
Article: High versus standard dose methylprednisolone in the acute phase of idiopathic thrombotic thrombocytopenic purpura: a randomized study.[Show abstract] [Hide abstract]
ABSTRACT: Therapeutic plasma exchange (PE) is the accepted therapy for thrombotic thrombocytopenic purpura (TTP). Because not all patients achieve remission, other treatment modalities have been used in addition to PE, but no randomized clinical trial evaluated their efficacy. The aim of this multicentric study was to compare the effectiveness of standard- versus high-dose methylprednisolone as an adjunctive treatment to PE in the acute phase of TTP. Sixty patients with idiopathic TTP were randomized to receive methylprednisolone 1 mg/kg/die intravenous or 10 mg/kg/die for 3 days, thereafter, 2.5 mg/kg/die in addition to PE. Both dosages of steroids were well tolerated. At the end of induction therapy (day 23), the percentage of patients failing to achieve complete remission was significantly higher in the standard dose (16 of 30) than in the high-dose group (seven of 30). Also, the number of cases without a good response at day 9 and the number of deaths were higher in the standard-dose arm, but the differences did not reach the statistical significance. Results of present study indicate that the association of PE with high-dose instead of standard-dose steroids reduces the percentage of TTP patients that fail to achieve complete remission.Annals of Hematology 06/2010; 89(6):591-6. · 2.87 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Desmopressin (DDAVP) may shorten bleeding time in patients with disorders of platelet function, but its mechanism of action in these conditions is still a matter of debate. In particular, contrasting results have been obtained concerning the ability of DDAVP to interact with platelets and to activate them directly. To gain further information on the DDAVP-platelet interaction, we studied the in vitro and ex vivo effects of DDAVP on platelet function. Platelet responses to DDAVP both as a single agent and in conjunction with agonists of platelet activation were investigated. For in vitro experiments platelets were obtained from healthy adult volunteers, while the ex vivo effects of DDAVP were studied in 12 patients with a bleeding disorder receiving a test dose of this drug. DDAVP in vitro did not induce either platelet aggregation or surface expression of the activation-dependent antigens; it did, however, greatly inhibit platelet aggregation response to vasopressin (AVP) and increased the maximal extent of platelet aggregation induced by collagen and ADP. DDAVP infusion did not promote the expression of activation antigens, but significantly enhanced ex vivo platelet aggregation stimulated by ADP and collagen. This priming effect was observed in patients with von Willebrand's disease, hemophilia A, May-Hegglin anomaly, gray platelet syndrome and Ehlers-Danlos syndrome. In all these patients bleeding time was shortened by DDAVP infusion. In contrast, neither platelet aggregation nor bleeding time was modified in two subjects with Glanzmann's thrombasthenia. Our in vitro experiments indicate that DDAVP interacts directly with platelets and facilitates their activation via other agonists. In vivo results suggest that this effect occurs and is clinically relevant in patients with platelet dysfunction responding to DDAVP with a shortening of bleeding time.Haematologica 11/1999; 84(10):891-6. · 5.94 Impact Factor
Article: Incompatibility for CD31 and human platelet antigens and acute graft-versus-host disease after bone marrow transplantation.[Show abstract] [Hide abstract]
ABSTRACT: Bone marrow transplantation (BMT) is often complicated by acute graft-versus-host disease (aGVHD). In patients transplanted with an HLA-matched donor the occurrence of this complication is believed to be favoured by disparities at the minor histocompatibility antigens (mHA). However, few of these polymorphic molecules have been identified. We sought to determine whether donor/recipient incompatibility for HPA-1, HPA-2, HPA-3, HPA-5 or CD31 (codon 125) antigens represented a risk factor for aGVHD and genotyped these antigens in 70 bone marrow donors and their HLA-identical recipients. All patients were children who received BMT for haematological malignancies at a single institution according to well-defined therapy protocols. Statistical analysis showed that incompatibility for CD31 (codon 125) was a risk factor for grade II-IV aGVHD in the overall patient population, whereas HPA-3 incompatibility predicted aGVHD occurrence in HLA-A2 patients only. The magnitude of the aGVHD risk was directly related to the number of HPA/CD31 incompatibilities. No correlation was found between non-identity for HPA/CD31 and aGVHD. Since incompatibility but not non-identity for CD31 or HPA-3 was a risk factor for aGVHD, we suggest that allelic variants of these molecules can serve as mHA in BMT recipients from HLA-identical donors.British Journal of Haematology 10/1999; 106(3):723-9. · 4.94 Impact Factor
Article: Relationship between size and thiazole orange fluorescence of platelets in patients undergoing high-dose chemotherapy.[Show abstract] [Hide abstract]
ABSTRACT: The reticulated platelet count relies upon the assumption that newly formed platelets contain a residual amount of RNA which selectively binds the dye thiazole orange (TO) and greatly enhances its fluorescence signal. It has, however, recently been shown that almost half of the platelet TO-signal is derived from the labelling of dense-granule nucleotides. It is therefore possible that the higher TO fluorescence of young platelets partially derives from the higher granule content due to their larger volume. To investigate the relationship between platelet size and TO fluorescence we studied 13 patients with high-risk breast cancer undergoing high-dose chemotherapy. Mean platelet volume, platelet distribution width, platelet-large cell ratio, membrane content of glycoprotein Ib and IIb-IIIa and platelet aggregation were significantly greater during resolution than during development of thrombocytopenia, suggesting a prevalence of young and old platelets respectively. Mean TO fluorescence per cell was higher in the platelet population enriched in young cells than in that enriched in old cells, but this difference was no longer observed when the ratio TO signal/platelet size was examined. Moreover, RNase treatment and platelet degranulation reduced TO fluorescence to a similar extent in platelet populations enriched in young or old cells. Therefore our data suggest that the higher TO signal of young platelets is derived, to a significant extent, from their larger volume and granule content.British Journal of Haematology 08/1999; 106(1):202-7. · 4.94 Impact Factor
Article: A new variant of Bernard-Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV.[Show abstract] [Hide abstract]
ABSTRACT: We describe a new variant of Bernard-Soulier syndrome characterized by almost normal amounts of GPIb and severely reduced GPIX and GPV. Despite surface expression, GPIbalpha failed to support ristocetin-induced platelet agglutination and to bind two conformation-dependent monoclonal antibodies, suggesting a qualitative defect. Sequence analysis of the gene coding for GPIX revealed a T-to-C substitution at base 1811, leading to a Leu40Pro conversion, whereas no defects were found in the coding region of the GPIbalpha gene. Allele-specific restriction enzyme analysis showed that the propositus and one of his sisters. both with severe bleeding diathesis. were homozygous for the GPIX mutation: the members of the family with mild bleeding diathesis and/or giant platelets in the peripheral blood were heterozygous, whereas the healthy ones were homozygous for the normal allele. Infusion of 1-desamino-8-D-arginine vasopressin normalized bleeding time in the two severely affected patients, although it did not modify ristocetin-induced platelet agglutination or membrane expression of GPIbalpha, GPIX, GPIIb-IIIa and GMP-140. Moreover, in one patient, normalization of bleeding time and rise of von Willebrand factor plasma concentration did not seem to be directly related.British Journal of Haematology 01/1999; 103(4):1004-13. · 4.94 Impact Factor
- Thrombosis Research 07/1998; 90(6):291-5. · 3.13 Impact Factor
Article: Thrombocytopenia, giant platelets, and leukocyte inclusion bodies (May-Hegglin anomaly): clinical and laboratory findings.[Show abstract] [Hide abstract]
ABSTRACT: May-Hegglin anomaly is a rare hereditary condition characterized by the triad of thrombocytopenia, giant platelets, and inclusion bodies in leukocytes. Clinical features and the pathogenesis of bleeding in this disease are poorly defined. From 1988 to 1996 we studied 15 new May-Hegglin anomaly patients from 7 unrelated Italian families. In addition to clinical examination and routine laboratory testing, we measured bleeding time, platelet aggregation and release reaction, and platelet staining for tubulin, and performed ultrastructural study of polymorphonuclear leukocytes. Although the mean age of our patients was 33 years, May-Hegglin anomaly had not been previously recognized in any of them. Bleeding diatheses ranged from severe to absent, and platelet count from 26 to 178 x 10(9)/L. No correlation was found between bleeding tendency and platelet count. Previous therapy with corticosteroids, high-dose immunoglobulins, and splenectomy had no effect on platelet count or bleeding diathesis. Desmopressin infusion greatly shortened the bleeding time in the most severely affected patient. The in vitro function of platelets was normal except for the absence of shape change in all subjects and defective response to epinephrine in 8 of 15 patients. Platelet tubulin was distributed unevenly instead of being organized in a circumferential band at the cell periphery. The diagnosis of May-Hegglin is easily missed, and its frequency is probably underestimated. A qualitative defect of platelets may be responsible for mild bleeding diathesis even in the absence of thrombocytopenia, while severe bleeding results from both qualitative and quantitative platelet defects. May-Hegglin anomaly should be suspected whenever a patient has a low platelet count or a bleeding diathesis of unknown origin.The American Journal of Medicine 05/1998; 104(4):355-60. · 5.30 Impact Factor
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ABSTRACT: We found that intracellular Ca2+ concentration ([Ca2+]i) increased during ristocetin-induced agglutination of aequorin loaded platelets resuspended in plasma. Chelation of extracellular Ca2+ had no effect on platelet clumping, but delayed and greatly reduced Ca2+ increase, indicating that it derived for the most part from Ca2+ influx. Nine monoclonal antibodies (MA) against glycoprotein (GP) Ib largely prevented ristocetin-induced platelet clumping and [Ca2+]i increase, while three anti-GPIb MA with no effect on platelet clumping did not interfere with Ca2+ movement. In unstirred samples platelet agglutination was greatly reduced and [Ca2+]i increase was abolished, suggesting that close platelet-to-platelet contact, in addition to von Willebrand factor (vWF) binding to GPIb, is necessary for Ca2+ transient. Nine MA against GPIIb/IIIa, the gly-arg-gly-asp-ser (GRGDS) peptide and GPIIb/IIIa complex dissociation had no effect on platelet agglutination, but significantly reduced Ca2+ increase. Our results suggest that platelet clumping induced by vWF binding to GPIb is responsible for GPIIb-IIIa dependent Ca2+ influx.Thrombosis and Haemostasis 05/1995; 73(4):689-92. · 5.76 Impact Factor
Article: Activation of the hemostatic process in patients with unruptured aortic aneurysm before and in the first week after surgical repair.[Show abstract] [Hide abstract]
ABSTRACT: It has been previously suggested that activation of coagulation and fibrinolysis may sometime occur in patients with unruptured aortic aneurysm. However, the incidence of this complication and the effect of surgical repair are unknown. The objective of our study was to gain further information on this topic. We investigated activation of the hemostatic process in 20 consecutive patients with unruptured abdominal aortic aneurysm. We then evaluated the effect of surgical repair of the vascular abnormalities. Both before and in the first week after surgery, the large majority of patients showed clear signs of activation of coagulation (increased plasma levels of prothrombin fragment 1 + 2 and fibrin peptide A), and many had low levels of the natural anticoagulant antithrombin III. Platelets were activated in all cases (high levels of plasma beta-thromboglobulin), and signs of platelet consumption (thrombocytopenia and/or increased mean platelet volume) were present in most of them. Activation of the hemostatic process occurs in nearly all patients with abdominal aortic aneurysm and could play a role in the hemorrhagic and thrombotic events that can complicate the clinical development of these subjects.Haematologica 82(5):581-3. · 5.94 Impact Factor
Article: Platelet composition and function in patients undergoing cardiopulmonary bypass for heart surgery.[Show abstract] [Hide abstract]
ABSTRACT: Previous studies showed severe biochemical and functional damage to platelets in patients undergoing cardiopulmonary bypass for cardiac surgery, and suggested that this derived from the proteolytic action of plasmin on the platelet surface. A double-blind study was carried out to compare platelet function and composition in patients randomized to receive the protease inhibitor aprotinin or placebo during reoperation for valvular prosthesis replacement or coronary artery bypass grafting. Flow cytometry with specific monoclonal antibodies and polyacrylamide gel electrophoresis did not show any significant proteolysis of platelet glycoprotein Ib and IIb-IIIa either in the placebo or the aprotinin group. Functional studies were consistent with these results, since ristocetin-induced platelet agglutination was unchanged and platelet aggregation and ATP release induced by collagen and ADP were only slightly reduced by cardiopulmonary bypass. These mild defects in platelet function were partially prevented by aprotinin infusion. On the basis of our data and those from literature, we suggest that platelets may be affected very little or severely damaged during cardiopulmonary bypass for cardiac surgery, probably depending on some aspects of the technical procedure which remain to be identified. Aprotinin infusion significantly protects platelets in the latter condition, while its role is obviously slight in the former.Haematologica 81(2):116-20. · 5.94 Impact Factor
Top Journals
University of Pavia
Pavia, Lombardy, Italy
- Department of Internal Medicine and Therapeutics


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Reel World
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Stale remake of '70s comedy knows the fine art of ripping people off
Film Review
Wolf Creek
Well-crafted slasher flick misses the heart, but gets the guts, at least
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Ledger, Gyllenhaal reach new heights with heartfelt drama
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Thursday 27th November 2014
Resort prices in the Costa del Sol have fallen 40% in five years, according to the latest research by the Post Office.
Its Holiday Money Report, which identifies holiday hotspots based on exchange rate trends and local costs in resort, found Spain was the second cheapest destination in 2012.
Turkey, once regarded as one of Europe"s cheapest destinations, could only achieve 17th place and was 60% more expensive than Spain.
Sarah Munro, Post Office head of travel money, said: "Given that sterling is worth around 20% more than a year ago against the Turkish lira, we expected to see a lower barometer cost for Turkey, especially as the country had a disappointing 2011.
"However, we were surprised to find that local costs have actually risen by 21% and it is only the strong sterling exchange rate that is masking that increase."
"It will be interesting to see how Turkish resorts respond to the challenge presented by Spain and Portugal. With Greek tourism also facing a fight for survival, we could see a price war between the eastern and western Med in 2012."
The report found sterling is stronger against 29 of its major currencies than a year ago, which will help deflect the pain of higher package prices and rising resort costs in two-thirds of destinations featured in the barometer.
The biggest rises were recorded in Kenya (+52%, £69.70) and Portugal (+39%, £45.58) - the latter falling from top spot in 2011 to seventh place this year.
Cyprus was the only eurozone destination of seven surveyed to show a clear fall in resort costs - down 8% (£53.19).
Sri Lanka was the cheapest by far of 40 destinations, rising from fifth place in 2011.
At £27.95 for eight items, including dinner for two with wine, a year-on-year fall of 31% made Sri Lanka 26% cheaper than runner-up Spain.
by Bev Fearis
Friday, January 13, 2012
Floodgates open as Supreme Court blocks Jet2 and Thomson appeals
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Couple fined for bad TripAdvisor review
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Propeller slices through cabin and injures passenger
WTM under pressure to dump fourth day
Couple fined for bad TripAdvisor review
Ryanair refuses refund after relative dies
Thomas Cook apologises for 54-hour delay
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Judges refuse to budge on air rage jail sentence
The results are in: eco-certification delivers better business for hoteliers
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Clarion Inn & Suites Atlantic City North
342 East White Horse Pike
Absecon, NJ 08205
Phone: (609) 272-8700
Fax: (609) 228-7580
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342 East White Horse Pike , Absecon, NJ, US, 08205
- Phone: (609) 272-8700
- Fax: (609) 228-7580
4.4 out of 5 (204 reviews)
87% of guests recommend this hotel
Library III
Located on the Black Horse Pike, Library III is a long-standing restaurant in Egg Harbor City, and it is known for its scrumptious steaks and wonderful lounge atmosphere. The setting is just like a typical library with tall book shelves and dim candle lights lining the walls of the dining room. Enjoy the onslaught of succulent steaks like the Prime Rib, Filet Mignon, New York Sirloin and Broiled Sea Scallops, along with Cajun Fries and Rice-Pilaf with Mushroom and Onion at the side. After the meal, walk up to the lounge of Library III and gulp down their specialty cocktails like Margarita and Martinis. As for the entertainment, the downstairs area is where the local and national bands strum out some amazing original tunes for the crowd.
6605 Black Horse Pike
Egg Harbor City, NJ 08234
+1 609 645 7655
Earn valuable points toward free nights.


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The VIZIO All-in-One Touch PC with Windows 8 delivers the best of both worlds, combining a powerful PC with premium entertainment features. A brilliant 24" or 27" Full HD ten-finger touchscreen with multi-gesture support gets the most out of Windows 8's revolutionary new features, while 3rd generation Intel Core® processors make jumping between the web, movies, games and work a breeze. It's everything you need in one beautiful design.
The VIZIO Co-Star decks out your TV with apps, full-screen Web browsing and the best in streaming entertainment. Co-Star packs the powerful features of Google TV into a sleek, intuitive interface.
VIZIO 60" Class Razor LED® Smart TV is a ultra-thin, edge-lit 1080p HD LED TV with 120Hz Refresh rate, built-in WiFi, and VIZIO Internet Apps - an unbelievable value under $1,000.
The VIZIO Thin + Light packs uncompromising entertainment and computing performance into an elegantly ultra-slim unibody design that stands up to life on the road.
The all-new VIZIO M-Series Razor LED™ Smart TV is the culmination of four years of research and consumer feedback, featuring the redesigned VIZIO Internet Apps Plus™ interface. The new easy-to-use interface is not only stunning, but is faster and packed with new features for an enhanced consumer experience. Just the kinds of changes you'd expect from the #1 smart TV brand in the U.S.*
*Source: The NPD Group/Retail Tracking Service, units sold
VIZIO is America's #1 brand in sound bars*** for a reason. If you're looking to complete your entertainment experience with a true surround sound audio, the VIZIO S4251W-B1 is the perfect audio upgrade for HDTVs 47 inches or greater. Movies, television, games, music, and more all burst to life with immersive sound and rich bass. The sound bar package includes everything you need to make the setup process smooth — all audio cables are included and built-in ubiquitous Bluetooth technology enables anyone to wirelessly connect a smartphone, tablet, PC, or other compatible device to the sound bar.** Create a digital jukebox at your next get-together, or just kick back and enjoy your favorite band in full 5.1 surround sound.
*** Source: Quixel Research units sold Q3 2013
**Wireless Subwoofer range approximately 60 feet – line of sight from Sound bar.
The new smart home system allows you to monitor and control your yard's watering schedule.
Lutron lighting control and Crestron home automation bring light, entertainment and security to luxury home.
The sensor network can monitor changes in moisture, temperature and humidity.
A look at the current and upcoming Blu-ray discs t that will support the new Dolby Atmos audio format.


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CLAP 3 - Pictograms
Put down your hog dog burrito, it time to learn the Chinese.4.56 / 5.00 7,570 Views
Hoenn Confirmed
Hoenn Intro Animated4.28 / 5.00 5,823 Views
Nites Episode 2
The second episode of Nites4.20 / 5.00 4,645 Views
It's the 8th wonder of the world! SBC is a purebred artist
very mysterious
I had to give it a five
It insulted all those stupid rapper, yo yo yo boys out there.
I don't get it....
...you're showing a lot of different random pics, but what is it supposed to be?
all hail strawberryclock!


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Slide Picture of Agyness Deyn in a Bikini
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Agyness Deyn slipped on her bikini while vacationing in Florida over the weekend.
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watereatsrock 4 years
What happened?
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What happened?
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yeah, exactly - who??? and um, she's interesting looking
Louie 4 years
Yikes. Brown hair does not suit her.
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- Find out why Kate Middleton reportedly cried during her appearance — Us Weekly
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- Rihanna's new album could drop before Christmas — Lainey Gossip
- Chevy Chase reportedly pulled a Johnny Depp at a recent event — Dlisted
- Did Kendra Wilkinson actually sleep with Hugh Hefner? — ET
- Kendall Jenner's latest model shot will make you do a double take — JustJared
- Bella Thorne stirs up trouble in her TV guest-starring role — Hollywood Tuna
- Prince just made a very bold move on social media — Pink Is the New Blog
- Christian Bale's surprising admission about the new Batman movie — The Superficial


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Fantastic view, nice photo! LIKE
Greetings, Alexander
Hello Alexander!
I'm very glad to see you, many thanks for your nice comments, I'm pleased that you li8ked this photo.
Have a nice day, Irina
Хороший пейзаж!
Спасибо, Виктор, хорошего навстроения, Ирина
Very Peaceful LIKE11 Greetings from Tunisia, Seb
Hello Seb!
Many thanks for your visit and kind words, especially i'm very pleased that you liked this pic.
Best wishes to you, Irina
Beautiful place and very good picture. L
Many thanks Agnieszka.c for your so kinsd cpmments and like.
With best wishes to you, Irina
Good Saturday morning to You my friend Irina
¤ Very, very beautiful summery landscape...July will miss.
¤ Magnificent old castle. ☺ ☺ ☺ I Like
¤ Have a nice weekend to You Irina
¤ Wish Arto
Good Saturday morning to You my friend Arto!
I'm glad to see you in my gallery. Thank so much for your nice comments, I'm happy you like it.
Have a nice weekend too, Irina
Many thanks dear friend Mehmet, I'm very pleased that you like this photo and have taken it in your favorites.
All the best for you, Irina
nice overview of this monastery and environment, like
Best wishes Jasper
Thank you Jasper very much for your so kind comments, I'm very glad that you like this photo
With best wishes to you, Irina
Beautiful photo and place!!like15
Thanks a lot dear mouzes for your visiting, nice comments and like.
All the best for you, Irina
Hi Irina,
A wonderful photo güzellikdeki amazing places. Up to date and better looking from the castle. Excellent shot. Beautiful presentation and sharing.
Best wishes, İsmail
Hello Dear Friends!
I'm so thankful for the friendly visiting with lovely comments and compliments. I'm so glad you liked my photo and that some of you have taken it to the favorites. I highly appreciate your opinion and attention to my gallery
With best warm wishes to all of you, Irina
Photo taken in Horodyshche, Khmel'nyts'ka oblast, Ukraine


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2014 Mercedes-Benz E-Class E550 2dr Coupe (4.7L 8cyl Turbo 7A)
Recently bought the Mercedes E550 Coupe. If you miss the open air feel of the a 60's muscle car coupe with no B pillar and gobs of horsepower and torque, then seriously consider this car. In fact, it is the only mid sized coupe with no B pillar and a big V8 engine currently available. Think a 1969 Pontiac GTO built by Mercedes; you would actually pay twice as much for a restored like new condition GTO and get half the car. I know, I owned one, and this car puts most any muscle car to shame including the new comparably priced Shelby Mustang; I had one if them too. 0-60 in 4.9 seconds, conservatively rated at 402 HP and 443 ft/lbs of torque, out handles any 60's muscle car, >20 mpg city/hwy.
Read the full review
2014 Mercedes-Benz E-Class E250 Sport BlueTEC 4MATIC 4dr Sedan AWD (2.1L 4cyl Turbodiesel 7A)
Just picked up a loaded, ordered spec 2014 E250. Selected this primarily for the Distronic Plus with Steering Assist, diesel range and AWD. Cost not a particular concern. M-B USA definitely miss the point here for all their 'marketing prowess' - international versions have smarter equipment choices. As everyone notes: no power folding mirrors!? Forget the rest of the gizmos, not being able to fold in mirrors easily in NYC in a luxury is incredible. Tiny nav screen, no available rear heated seats, old fashioned Apple 32-pin connector on s new 2014 model).. c'mon how much are the bean-counters at M-B USA really saving here? Not a good first impression compared to my BMW Porsche or Range Rover.
Read the full review
2014 Mercedes-Benz E-Class E550 2dr Convertible (4.7L 8cyl Turbo 7A)
This is a dream car come true.
I love the performance, the build quality, the technology is amazing!
My wife and I have 2 children and love top down driving!
With the windows up and the air cap all four of us can talk with the top down doing 70 mph on the interstate.
I have researched convertibles for 2 years before I ordered this car.
I looked at BMW 6 series convertible, Audi RS5 convertible to mention a few.
Without question, none of them come close to the E550 cab.
If you are looking for performance, comfort, technology, cruising for a family of 4 this is it!
I enjoy the driver assistant package.
In stop in go traffic it does the driving!
Read the full review
2014 Mercedes-Benz E-Class E350 2dr Convertible (3.5L 6cyl 7A)
The Mercedes E350 convert is brand new for 2014 - a redesign, and well worth it. The interior is just sick....The Premium 1 Package anlong with the Sport Package are a must have with this car. The AMG wheels, wood and leather steering, Keyless Go options are a must. The Harman/Kardon Logic 7 stereo system, Navi & Rear Camera com[plete the driver experience. Bought it for my wife, and happy wife = happy Life - Sticker @ $68,945 - out the door in September $60,842 - wow
Read the full review
2014 Mercedes-Benz E-Class E350 2dr Coupe (3.5L 6cyl 7A)
Sporty yet comfortable. Better than expected mpg.
Standard sound system superb. Switched from Audi because they did not have comparable coupe. This is nicest car I ever owned
Read the full review
2014 Mercedes-Benz E-Class E550 2dr Coupe (4.7L 8cyl Turbo 7A)
Have been driving my new 2014 E550 Coupe for about a week, and it is remarkable. I switched from a BMW 535 and there is no comparison. The E550 is a rocket, rides like a dream, and contrary to some places write, I feel much more connected to the road. The interior is gorgeous, exterior is sleek and beautiful, and the technology is fantastic. I was a little worried that the Lane Departure, Blind Spot, and other systems might be intrusive, but frankly, make it even more fun to drive. Gas mileage is about what you would expect, though the on/off feature should help, and is virtually unnoticed when stopped.
Sound system is also first ate
Read the full review
2014 Mercedes-Benz E-Class E350 Sport 4dr Sedan (3.5L 6cyl 7A)
I purchased my brand new 2014 e350 in May 2013. Unfortunately someone rear ended it two weeks later. It has been over 2 months and Mercedes is unable to replace the rear bumper on my car. They cannot give me an answer to when they will have the part. I did not expect this from Mercedes. Beware people before you buy Mercedes. Are they going bankrupt?
Read the full review
2014 Mercedes-Benz E-Class E350 Sport 4dr Sedan (3.5L 6cyl 7A)
I just purchased my 2014 Mercedes Sport Sedan.
The new design of the front grille-work, rear quarter panels and rear end are a marked improvement over the 2010-2013 models.
The vehicle handles and corners beautifully and the ride seems more solid and smoother than previous models, all of which I have owned.
The newly designed dashboard, instrument cluster and NAV screen are truly rich and stunning.
They have included ECON start/stop for improved city fuel economy.
It cuts the engine when the car comes to a complete stop and your foot is on the brake.
Once you remove your foot from the brake, the engine automatically restarts.
This feature can be disabled, if desired, by button.
Read the full review
2014 Mercedes-Benz E-Class E63 AMG 4MATIC 4dr Sedan AWD (5.5L 8cyl Turbo 7A)
Picked up my e 350 today .It ia black with silk beige interior it has amg wheel package rear spoiler
split rear seats p1 package lane tracking and blind spot indicator package.It is similar to my 2012 e 350 . The front and rear ends are new the shape is the same as my old one .The ecostart take some getting used to , there is a button to shut it off.The look of the car is great ,so is the ride.Some new safety features are standard such as collision avoidance . There is a control to change the ambient lighting in the car . You have a choice of three colors. Really like the agressive look of this car. Cant wait to open it up
Read the full review
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Great bulbs, faster delivery
Reviewed By Michael B (Sparta, MI) Reviewed for a 2002 Pontiac Grand Am —2/19/2013 9:41 AM
Ordered the superwhite headlight bulbs for my 2002 Grand Am GT. Arrives in less than a week.
Reviewed By Brian B (NORTH LIBERTY, IA) Reviewed for a 2007 Toyota Camry —11/23/2014 8:36 AM
I installed these in my wife's Camry and although they are brighter than the OEM lamps, they are not quite as bright as assumed. Better than the precious ones though, and white/blue light allows for better road clarity.


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Cheadle Town ended their run of seven games without victory in emphatic style against Wigan Robin Park.
Cheadle Town's dismal run of results continued as they bowed out of the First Division Trophy on penalties to Hanley Town. View Item »
Cheadle Town lost out by the odd goal yet again as they tumbled out of the Cheshire Senior Cup to Northwich Flixton Villa. View Item »
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Cheadle Town were amongst the goals yet again over the weekend but were on the end of yet another defeat as Cammell Laird won 4-3. View Item »
Irlam came away from Park Road Stadium with the three points following a disappointing performance by Cheadle Town. View Item »
Cheadle Town lost out by the odd goal in seven in this thriller at New Sirs. View Item »
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Prince Charles carries out whirlwind tour of Cumbria
Last updated at 16:48, Tuesday, 03 April 2012
If the snow and driving rain put off Prince Charles during his visit to Wigton he certainly didn't show it.
His Royal Highness shook hands, chatted to locals and accepted gifts while walking through the town centre this afternoon.
The visit was in recognition of the 750th anniversary of the town's Market Charter and involved trips through the town's Youth Station, the Fountain Art Gallery and St Mary's Church before heading to the Market Hall and viewing assembled exhibits.
Despite the unseasonable snow, townsfolk turned out in huge numbers and were delighted by the Prince's friendly and easy-going nature.
For a full report of the Prince's visit to Wigton and more pictures see tomorrow's News & Star.
After leaving Wigton, he viewed presentations from youngsters supported by The Prince's Countryside Fund in Cumbria and met fund supporters at a reception at Greystone House Farm in Stainton.
The final stop in his whirlwind tour was Dalemain, near Penrith, to celebrate the eighth International Dalemain Marmalade Festival and Awards. He was due to taste marmalade entries from this year's festival and meet supporters and volunteers.
For a full report and pictures of the Prince's visits to Stainton and Dalemain see tomorrow's News & Star.
The Prince of Wales had a packed schedule for his day in Cumbria.
It began with a morning tipple as he helped mark the 10th anniversary of Hawkshead Brewery.
He pulled a pint of Windermere Pale and gave the royal seal of approval to the aromatic beer, saying it was "hoppy" and "tasty".
The firm is among 40 located on a "green" business park in the South Lakeland village of Staveley.
Charles unveiled a plaque to commemorate the company's anniversary and was presented with a selection of bottled ales.
He chatted with other business owners and also toured More? The Artisan Bakery run by local couple Patrick and Louise Moore.
Mr Moore's seven-year-old daughter Milly presented The Prince of Wales with a bread basket of more goodies.
Charles also dropped in at handmade furniture makers Waters & Acland, where he was given a view of its craftsmanship and met the firm's first apprentice.
He then went on to meet staff and volunteers at Dove Cottage - the home poet William Wordsworth shared with his sister Dororthy from 1799 to 1808 - and the next-door Wordsworth Museum.
Charles - patron of the Wordsworth Trust - studied a passage in Dorothy's diary which inspired the poem Ode - Intimations Of Immortality from recollections of early childhood, which he chose as a reading at his wedding to the Duchess of Cornwall in 2005.
First published at 16:45, Tuesday, 03 April 2012
Published by http://www.newsandstar.co.uk
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Venture Capital
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Cambrian raises $10M for DNA printing tech used by GSK
Proponents of DNA printing have heralded it as a way to do everything from bringing alien life back from Mars to delivering vaccines in the event of a pandemic. And the technology has attracted GlaxoSmithKline and Roche, both of which have taken an interest in Cambrian Genomics.
Novartis VC unit co-leads $53M investment in BioNano Genomics
BioNano Genomics has restocked its coffers to fund an assault on the genome analysis sector. The San Diego, CA-based genome mapping firm raised a $53 million war chest from Novartis' venture fund and other investors to accelerate uptake of its Irys DNA analysis device and accompanying software.
BioNano bags $53M to dig deeper into genomics with Novartis on board
San Diego's BioNano Genomics has raised a $53 million C round to bankroll its efforts to decode the so-called inaccessible genome, adding Novartis to its investor syndicate as it works to amplify its profile.
U.K. heavyweight Woodford gambles $25M on controversial brain cancer vaccine
U.K. biotech investment heavyweight Neil Woodford has invested $25 million in the U.S. biotech Northwest Biotherapeutics, gambling that its controversial Phase III study on a new therapeutic vaccine for brain cancer comes up a winner.
Juno takes its hot CAR-T cancer tech to Wall Street in $150M IPO
In what will likely be the most closely watched IPO in biotech, Juno Therapeutics has rolled out a $150 million offering that is likely to make a big splash on the market.
Blueprint Medicines banks $50M for its personalized take on cancer
Third Rock Ventures startup Blueprint Medicines has hauled in a $50 million C round, cash that'll see its way through clinical trials and keep its promising platform generating new candidates.
Fledgling Ziarco grabs a $33M transatlantic round for PhII atopic dermatitis drug
Two years after Michael Yeadon and a close-knit group of Pfizer investigators managed to grab some of the pharma giant's anti-inflammatory assets on the way out the door at Sandwich, they've drummed up a $33 million B round for their biotech from some U.S. and European investors. And now they're set to launch a midstage clinical program to help determine the value of what they took with them when launching Ziarco.
Trevi wraps up a $26M round to fund its anti-itching drug
New Haven, CT's Trevi Therapeutics banked another $11 million in venture cash, bringing its B round to $26 million and giving it the cash it needs to complete a pivotal trial for its top prospect.
Tolero wraps up a $22.4M round to support its cancer contender
Tolero Pharmaceuticals has pocketed a second tranche of its Series B funding round, netting $22.4 million in total as it prepares to take its expirimental marrow cancer treatment into late-stage development.
Novo Nordisk pushes back date of IT IPO decision to 2015
Having spent the past 10 months weighing up the merits of a separate listing for its IT subsidiary NNIT, Novo Nordisk has decided it needs to wait a little longer before pulling the trigger.


text: ESPN Feed: 5 on 5 http://assets.espn.go.com/i/tvlistings/tv_espn_original.gif ESPN en-us 10 ESPN Inc. http://espn.go.com/ Copyright 2010 ESPN Inc. Ed Orgeron has spent 27 years coaching football, but until this spring he had never directed a 5-2 defense. Now he's learning on the fly and loving it.]]> April 24, 2013 07:36:52 PDT Colorado has been scuffling en route to a 1-5 start, not the best way to enter a game against USC.]]> October 16, 2012 15:00:41 PDT


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i have been a faithful user of seche vite for years, but was frustrated by how quickly it chipped. this review will mostly be a comparison of the 2 products. i have the newer packaging of the mega shine - mirror shine.
1. drying time: seche vite > mega shine. nothing beats how quickly the seche vite top coat dries. the mega shine does take just a bit longer, but much faster than normal nail polish on its own.
2. shine: seche vite > mega shine. seche vite gives such a glossy finish...i think it is one of its highest qualities. the mega shine is pretty dull and not as smooth as the seche vite. the whole "mirror shine" aspect is definitely lacking.
3. texture: mega shine > seche vite. the mega shine is much thinner in terms of consistency, which makes it much easier to spread over the nail.
4. scent: mega shine > seche vite. i have no idea why the seche vite smells so strong. the mega shine doesnt smell good by any means, but it is typical for nail polish and not so severely offensive as seche vite.
5. packaging: mega shine > seche vite. i LOVE the wide, flat brush that the mega shine comes with. i can coat my entire nail w/2 swipes.
6. price: mega shine = seche vite. i'm a little confused here since seche vite is supposed to be "high end" and sally hansen drugstore, but they are both $9 wherever i go. sure, there are always coupons for sally hansen in the sunday paper, but ulta also has sales on seche vite from time to time. neither top coat has the clear advantage here.
7. durability: mega shine >>> seche vite. when i use seche vite, my polish chips probably starting the 3rd day...with weird shrinkage towards the tips of my nails on the first day. i have had the mega shine last on my nails for a full week without ANY chipping (and i am a notorious cuticle picker). i don't know about 10 days, but i have has my polish last a full week.
i know that the seche vite gets incredibly thick and goopy once it passes the halfway mark, but i don't know if this is true of the sally hansen just yet. i've used this for about 5-6 manicures so far, but i'm not at the halfway point. it's something to consider cuz previous reviewers have mentioned it.
bottom line: mega shine > seche vite.
11 out of 11 people found this review helpful. Did you? Yes No
I have gone through about 3 or 4 bottles of this and I absolutely love this top coat. I was using the Seche Vete or however you spell it and I stopped using it once I found out about how toxic it is and I have been using this ever since. This is relatively cheap but it works perfectly as a top coat. I have not found anything else that makes your nails anywhere near as shiny as this does and it makes your nails dry to the touch in about two minutes or so but you still need to wait about five to ten for them to be really dry so the "dry in 60 seconds" claim is a bit of a let down because they still do that thing where the polish is dry but smushed if you do anything before they are really dry if that makes any sense. You do have to reapply about once every four or five days because the ends get somewhat dull after awhile and lose that really mirror finish. Also, the chrome coating on the bottle chips off sometimes so that is just something to keep in mind because it gets everywhere after awhile. Overall the actual nail polish itself is ridiculously shiny and it dries quickly. Also, I am someone who paints there nails like every three or four days because I get tired of seeing the same color so I do my nails a lot and it still takes me forever to go through a bottle of this because you really only need one thin coat and you are good to go. A must-have in my book.
1 out of 1 people found this review helpful. Did you? Yes No
This is my absolute favorite top coat. It goes on without streaking my polish and dries super quick. My nails look like I have had a professional manicure/pedicure whenever I use this. To top it off, I found my bottle in the Dollar Store! My only complaint is that I can't see through the bottle and have no idea how much more is left.
I swear by this product. It gives natural nail manicures the kind of shine you get with artificial nails. It lasts, maybe not 10 days, but at least 5 days before it starts chipping. Just don't apply too thickly. Oh, and the bottle gets a little crusty at the opening after a couple of uses - when this happens be careful not to get the crust onto your manicure. But the biggest plus: it really does dry in less than 5 minutes. I mean you can go to sleep right after with little to no issue, that's how dry it gets!
1 out of 1 people found this review helpful. Did you? Yes No
Price is good and it is available in the grocery stores. I agree with the other reviewers who said they don't like that the bottle is opaque and the brush is white...we can't see the product so we have to assume how much is on the brush and how much is left in the bottle.
Quality is another downside to this product. It dries quickly yes so I have never gotten sheet marks or dents and I can get on with my life quickly. The shine is okay but I have used a shinier polish (Beauty Secrets, which is what I intend to go back to if I am not satisfied after trying Poshe next) The Sally Hansen Mega Shine makes my polish chip easily and is very brittle so on day two or three, my polish begins peeling in one single layer like paint off a wall. I would not buy this again.
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I'm really surprised with the low ratings of this top coat. After several 'manies', I have come to the conclusion that this is the best top coat for me. I originally have been using SH's Insta dry anti-chip top coat for years and loved its performance. I didn't think I would find anything else that would beat it. This mega-shine top coat, (an acciental purchase) keeps my nail colour as shiny through at least 5 days without chipping! My nail polish looks as good on day 4 as it did within day 1. I normally get antsy after 3/4 days of nail polish and want to change, but this top coat keeps my mani so fresh looking each passing day that I get lasy to remove. Only until they have chipped like crazy that I will remove it, which will be at least 6+ days after the mani. Anyways, overall I will rebuy this. It has great shine, seals polish in like a rock and is long-wearing. (In Canada it's about 8 bucks at Shoppers or less at Walmart.)
More reviews by prettyseaeagle
This is my second bottle as I totally dig this stuff. It dries polish fast and gives a mirror-like shine. However, like what previous reviewers had mentioned, the application is tricky. Apply too much and you get a thick layer atop your manicure when dried. If you apply too little, streaks can be very obvious on light polishes. Also, this doesn't make your manicure last longer as I see tip wear around the second day. I have tried Seche but it didn't work for me and I hated how fast it thickened. I have another Poshe top coat unused though, if that works better I will probably not repurchase.
After trying Poshe, SV, Out the Door and Essie 3 way glaze, this has become my HG topcoat, Fast drying, and extremely shiny, while applying easy. My only complaint is that it does not cooperate at all with Zoya polishes-I get massive shrinkage around the cuticles, sides of nails and tips when I use it, so opt for the Insta-Dri for Zoya only. I do wish the bottle was see-thru just so getting the right amount on the brush would be easier, and to know when you are running low
I cannot believe the bad reviews I have read about this product! If used properly it is wonderful! The product says that you can use while nails are still wet, but I do suggest that you wait until fully dry. Also it does not last the full 10 days as it suggests. But this polish gives a beautiful mirror shine top coat, a very professional looking finish. People are always asking where I got my nails done...at home!
Don't waste your money on this product. It smeared my polish, took ages to dry, cost as much as seche vite. Wish I could give it no lippies.