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PowerPoint Recovery Toolbox 2.2.1
Download PowerPoint Recovery Toolbox immediately after the occurrence of data corruption problems in PPT presentations and increase your chances of repairing PowerPoint files. It is easier than you think, all PPT repair activities can be performed intuitively and without any help. The detailed description of PowerPoint Recovery Toolbox is not really needed so you may keep on working intuitively and without additional explanations.
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EDB to PST Converter Toolbox 2.0.3
Powerful and intelligent software, repairing damaged Exchange folders of any size and version so you can now convert corrupted information among popular email formats regardless the state of input files. EDB to PST Converter Toolbox is easy and friendly data recovery program that guarantees the privacy of valuable data during the process of email conversion, get its freeware version and start converting EDB files in two clicks.
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MySql Recovery Toolbox 2.0.1
MySql Recovery Toolbox is the easiest method of repairing corrupted databases in the MySql format, this approach is much easier than other ways of keeping databases safe and there is no need to pass additional trainings and read instructions. You may simply install this application on your PC and follow its friendly guidelines, some kind of additional explanations are not needed. The size of database recovery tool is approximately 2 megabytes.
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Lotus Notes Recovery Toolbox 2.1.2
Get Lotus Notes Recovery Toolbox is something goes wrong and *.nsf files are corrupted for any reason. If these files were not backed up previously, you may try this application and restore the data from *.nsf files in a minute without any difficulties. Free version of Lotus Notes Recovery Toolbox is available for download anytime the damage of Lotus Notes files occurs, it works on any computer without the loss of performance.
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Auto Maintenance Plus 9.6
Auto Maintenance Plus should capitalize the PLUS. You get a database to record your automobile expenses for maintenance and repairs as well as a separate table to list original cost, insurance, and license information on all your vehicles. Plus enter photos and more.
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Pointstone Registry Cleaner 4.10
With Registry Cleaner you can safely clean, repair and optimize the Windows registry with a few simple mouse clicks! Problems with the Windows registry are a common cause of Windows crashes, slow performance and error messages. By using a registry cleaner regularly and fixing registry errors your system should not only be more stable but it will also help improve your system performance without expensive hardware upgrades.
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CD Fix Toolbox Free 1.0.0
CD Fix Toolbox Free is the repair tool for optical disks. How to fix damaged CD/DVD/Blu-Ray optical disk? CD Fix Toolbox Free helps to recover files from optical discs (CD/DVD/Blu-Ray). CD Fix Toolbox Free read corrupted disc and save a recovered files on HDD.
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CD Repair Toolbox Free 1.0.0
Data recovering from optical discs (CD/DVD/Blu-Ray) with help of CD Repair Toolbox Free. How to repair CD/DVD/Blu-Ray disk? CD Repair Toolbox Free reads data from damaged optical discs (CD/CDR/CDRW/DVD/DVD-R/DVD+R/ DVD-RW/DVD+RW/DVD-RAM/Blue-Ray/BD-RE) and saves recovered data to other media: hard drive or flash drive and others.
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DBF Recovery Toolbox 2.1.2
Try DBF Recovery Toolbox and retrieve the data from corrupted databases of DBF format that were damaged for any reason. This application recovers the data from damaged documents and converts the contents of corrupted databases into clean files of DBF format. It is much easier than any other database processing activity, it looks like the decompression of zipped documents, follow the guidelines it is all you may do.
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PDF Recovery Toolbox 2.1.0
Get PDF Recovery Toolbox if you encounter the damage of Adobe Acrobat documents, this approach to the safety of corrupted PDF files is often easier than other methods of PDF file repair. It is cheaper than some other data recovery services and allows repairing more information than similar applications and other ways of keeping the data safe. Get it from the website of PDF Recovery Toolbox and start evaluating.
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Word Repair Toolbox 2.2.1
Word Repair Toolbox makes recovering damaged Microsoft Word documents simple and easy to perform without the need for specialist computer skills or expertise. You can save recovered Word documents as either a new Word file or as a text file and there is also a very handy preview function to view recovered data prior to export or saving. Word Repair Toolbox works with MS Word 95, 98, 2000, XP, 2003, 2007, 2010 and RTF format files. Download today!
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Illustrator Recovery Toolbox 2.1.0
You may evaluate Illustrator Recovery Toolbox and start fixing data corruption problems immediately without the usage of other complicated data recovery utilities and expensive data recovery services. This approach represents an easy way of data recovery that can be applied by beginners or experts, you may simply follow all guidelines of Illustrator Recovery Toolbox and proceed to the analysis of AI files as soon as you need.
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Amigabit Registry Cleaner 22.214.171.124
Amigabit Registry Cleaner is a solid program to scan, clean and repair Registry errors causing slow speed, PC crashing or freezing, blue screens, error messages, etc. with simple, one-click option. It also automatically backup any repairs made. So you always can restore Windows registry to the original state using restore button.
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Windows Boot Genius 1.0.0
Windows Boot Genius is the comprehensive windows boot savior. It can repair crashed or corrupted operating system and help you solve Windows boot up issues like blank/blue screen, freezing screen, etc. It can do that, and much more. Below are some key features of Windows Boot Genius: Highlights of Windows Boot Genius Make a Windows Boot CD/USB Windows Boot Genius lets you burn bootable .iso file to CD or USB drive. You can use the boot CD/USB to boot inaccessible system and recover system files. Various Windows Boot Repair Tools There are several boot repair tools included in the program. For example: boot file repair, boot sector repair, registry repair, registry editor, etc. They can help you solve Windows boot failure issues like black/blue screen of death, system crash, etc. Reset, Change or Remove Windows Local and Domain Password If you are locked out of Windows, you can use Windows Boot Genius to help you reset or remove lost or forgotten password. It also can create a new account to log ...
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Tenorshare ReiBoot 18.104.22.168
Tenorshare ReiBoot is the totally free Mac iPhone reboot software. It fixes iPhone, iPad and iPod Touch stuck in Recovery Mode after iOS 7 upgrade, restore, jailbreak, etc. With this free Windows iPhone boot loop repair tool, only 1 click, you can put iPhone out of Recovery Mode or let your iOS device go into Recovery Mode freely. This tool is totally risk free! No need to worry about data loss or damage. Key Features of Tenorshare ReiBoot 1. Completely free. 2. One Single click to enter or exit Recovery Mode, no need to operate your iOS device. 3. It will not clear data and do any harm to your device. Unlike Apple iTunes, which forces you to restore your device and delete all data. 4. Work for all iOS devices. Such as iPhone 5s/5c/5/4S/4/3GS, iPad Air/mini/4/3/2, iPod Touch 4g/5g, etc. 5. Compatible quite well on Windows 8.1/8/7/XP/Vista, Windows server 2000/2003, etc. 6. Supports iOS 7/6/5/4/3, etc.
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Warp Registry Cleaner Software 1.04
Warp is free registry cleaner software you can use to speed up your PC by cleaning and optimizing the Windows registry, removing old, damaged and unneeded data that can bog down your computer's performance. Registry cleanup can improve the speed and stability of your PC making it run like new with fewer error messages and crashes.
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Corrupt XLSX Salvager 2.0.4
Corrupt XLSX Salvager will recover data from corrupted unopenable Excel XLSX extensioned files and convert it to CSV. It succeeds at doing so sometimes where Excel 2007-2013 fails to salvage data. A new 'Alternatives' menu and zip repair pretreatment extend its usefulness. It can also be simply used as a viewer of the unformatted data in an xlsx file without having Excel 2007 or 2010 installed.
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YAC (Yet Another Cleaner) 3.7.39
Yet Another Cleaner is a all-in-one FREE professional tool to keep your PC safe, clean and fast, removes harmful files from your PC and repairing your operating system. Protects from browser hijacker, malicious plug-ins, malwares and different viruses. It can help you get rid of unwanted browser hijacker like Qvo6, delta and V9 etc... Clear cache/browser history and boost slow computers. Just by ONE CLICK Yet Another Cleaner will take any PC problems away. Key Features: Completely FREE, effective, robust and highly reliable software that increases computing productivity by keeping PCs running smoothly and error-free. An All-In-One virus removal tool. It will keep your PC and browser safe, clean and efficient with just ONE CLICK. Browser hijacker removal. It can help you get rid of unwanted browser hijacker like Qvo6 and delta. Create and Protect your own default homepage Malware removal. It can detects and help you get rid of unwanted toolbar like dealply and webcake. Protects your PC from any malicious ...
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Corrupt Office Salvager 1.0.3
Corrupt Office Salvager provides 2 methods each for recovering text/data from corrupt unopenable MS Office, Word, Excel, PowerPoint files and Open Office files. It can also attempt to recover formatting for just the OO files. A new 'Alternatives' menu and zip repair pre-treatment for zip based files extends its usefulness. One of the Alternatives,a coupon 'S2SERVICES' for a $39 recovery from Recoveronix Online File Recovery good until 11/01/2014.
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Access Recovery Toolbox 2.0.2
Get Access Recovery Toolbox if you encounter data corruption issues, affecting the integrity of MDB databases, used by the Microsoft Access application. This program supports all available hw configurations therefore you may quickly recover corrupted databases of supported format and convert the data into clean and trouble-free documents of MS Access supported formats. Follow the guidelines of MDB recovery tool and get it for evaluation.
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DataNumen PSD Repair 2.0
DataNumen PSD Repair(DPSDR) (formerly Advanced PSD Repair) is a powerful tool to recover corrupt Photoshop image(PSD, PDD) files. It uses advanced technologies to scan the corrupt or damaged Photoshop image files and recover your data in them as much as possible, so to minimize the loss in file corruption. Currently DPSDR supports to recover PSD and PDD image files produced by all versions of Adobe Photoshop.
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DataNumen Database Recovery 2.0
DataNumen Database Recovery (DDBR) is a powerful database recovery suite. It includes recovery tools DataNumen Access Repair (DACCR) and DataNumen DBF Repair (DDBFR). DACCR can repair corrupt Access databases. MS Access 95 to 2013 are supported. DDBFR can recover corrupt DBF files. All versions of DBF databases, including dBASE, FoxBase, FoxPro, Visual FoxPro are supported. DDBR is your ideal solution for database disaster recovery.
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Outlook Recovery Toolbox 3.1.7
Choose Outlook Recovery Toolbox for data recovery purposes, repairing Microsoft Outlook folders. This program represents a powerful way of ost and pst file analysis, it can be performed after the occurrence of any problem causing the corruption of user mailboxes. This tool is the only way of getting the data back without losing the privacy of your personal information. Besides it is safe and it never puts modifications to the mailbox under.
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DVD Store 2.1
DVD Store decrypts write protected DVDs and copies the files you choose from your DVD to your local hard drive. You then have the option to convert the files into Flash Video format for playback in your media player or for web page display. Gives you a backup copy of your valuable DVDs which can be destoyed from dirt and scratches from improper handling. Comes with FFMPEG converter utility that automatically converts files to flv format for playback in Real Player or other media players. Build a library on your computer that you can access without loading individual disks. See for yourself the high quality videos created. Few programs if any have the ability to read DVDs with write protection that this program handles. Comes with free lifetime upgrades and technical support, no yearly subscription fee. Buy any one program from our home page and get one program of equal or lesser value free!
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SQL Server Repair Toolbox 2.1.4
SQL Server Repair Toolbox repairs Microsoft SQL Server databases created under all major versions of Microsoft SQL Server. Simply repair data types, table data, stored procedures, functions, triggers, indexes, primary keys, foreign keys, constraints and more. Preview recovered data and selectively save data after recovery. You can also repair SQL databases made up of multiple files, work with table partitions and much more. Download today!
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Publications (99)312.8 Total impact
Article: No Improvement of High-Density Lipoprotein (HDL) Vasorelaxant Effect Despite Increase in HDL Cholesterol Concentration in Type 2 Diabetic Patients Treated With Glitazones.[Show abstract] [Hide abstract]
ABSTRACT: Context: High-density lipoproteins (HDLs) from type 2 diabetic patients are unable to counteract the inhibitory effect of oxidized low-density lipoproteins (ox-LDLs) on vasorelaxation. We hypothesized that glitazones, which improve glycemic control and dyslipidemia, could correct this abnormality. Objectives and Design: We compared the ability of HDL from controls (n = 12) and from type 2 diabetic patients before and after 6 months of treatment with either rosiglitazone (n = 11) or pioglitazone (n = 8) to counteract the inhibitory effect of ox-LDL on vasodilatation of rabbit aorta rings. Results: Rosiglitazone induced a decrease in hemoglobin A1c (7.7% ± 1.1% vs 9.8% ± 1.0%, P = .003) and an increase in HDL cholesterol (1.14 ± 0.32 vs 0.98 ± 0.24 mmol/L, P = .033). Pioglitazone induced a decrease in hemoglobin A1c (8.3% ± 2.5% vs 9.5% ± 3.2%, P = .068) and serum triglycerides (1.58 ± 0.89 vs 2.03 ± 0.70 mmol/L, P = .069) and an increase in HDL cholesterol (1.39 ± 0.22 vs 1.14 ± 0.22 mmol/L, P = .018). The triglyceride content of HDL was unchanged by rosiglitazone and was decreased by 25% (P = .068) by pioglitazone. HDL from controls counteracted the inhibitory effect of ox-LDL on vasodilatation (maximal relaxation [Emax] = 74.4% ± 3.5% vs 51.9% ± 3.3%, P = .0029), whereas HDL from type 2 diabetic patients did not (Emax = 51.7% ± 5.8% vs 52.3% ± 4.6% [P = .66] and 52.7% ± 5.5% vs 51.9% ± 4.5% [P = .78] for the rosiglitazone and pioglitazone group, respectively). Rosiglitazone or pioglitazone did not improve Emax (58.6% ± 5.9% vs 52.3% ± 4.6% [P = .15] and 49.3% ± 6.5% vs 51.9% ± 4.5% [P = .48], respectively). Conclusion Glitazones increased the concentration of HDL cholesterol without restoring the ability of HDL particles to protect the endothelium from oxidative stress-induced dysfunction, meaning that HDL remained dysfunctional with impaired antiatherogenic properties.The Journal of clinical endocrinology and metabolism. 08/2014;
Article: Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicentre tracer kinetic study.[Show abstract] [Hide abstract]
ABSTRACT: Context: Low plasma HDL cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as VLDL subspecies (VLDL1, VLDL2) kinetics, liver fat or visceral adiposity, remain to be investigated. Objectives: Our aim was to study the associations between HDL apoA-I fractional catabolic rate (FCR) and the kinetics of VLDL subspecies and estimates of liver, visceral and subcutaneous fat. Design: We carried out a multicentre in vivo kinetic study using stable isotopes (deuterated leucine and glycerol) in 62 individuals with abdominal obesity. Results: In multivariate analysis, among the morphological and biological parameters that may predict ApoA-I FCR, liver fat (β=0.400, p=0.003) and VLDL1-apoB (β=0.307, p=0.020) were independently associated with apoA-I FCR. In multivariate analysis, among the kinetic parameters, VLDL1-TG indirect FCR (β=-0.357, p=0.001), VLDL1-TG PR (β= 0.213p=0.048) and apoA-II FCR (β=0.667, p<0.0001) were independently associated with apoA-I FCR. After adjustment for VLDL1-TG PR, liver fat was no more correlated with apoA-I FCR. No association between apoA-I FCR and visceral fat was observed. Conclusions: We show that VLDL1 is an important independent determinant of apoA-I FCR and more precisely that apoA-I FCR is independently associated with both catabolism and production of VLDL1-TG. In addition, we show an association between liver fat and apoA-I FCR that is mostly mediated by VLDL1-TG production. These data indicate that, in abdominal obesity, dysfunctional VLDL1 metabolism is an important modulator of HDL apoA-I catabolism.The Journal of clinical endocrinology and metabolism. 07/2014;
Article: Oxidation-induced loss of the ability of HDL to counteract the inhibitory effect of oxidized LDL on vasorelaxation.[Show abstract] [Hide abstract]
ABSTRACT: Several current diseases are associated with an increase in the oxidation of HDL, which is likely to impair their functionality. Our aim was to identify whether oxidation could change the protective effect of HDL against the deleterious effect on vasoreactivity induced by oxidative stress. HDL from healthy subjects were oxidized in vitro by Cu(2+), and the ability of oxidized HDL to counteract the inhibitory effect of oxidized LDL on acetylcholine-induced vasodilation was tested on isolated rabbit aorta rings. Oxidation of HDL was evidenced by the increase in the 7-oxysterols/cholesterol ratio (3.20 ± 1.12 vs 0.02 ± 0.01 % in native HDL, p < 0.05). Oxidized LDL inhibited endothelium-dependent vasodilation (E max = 50.2 ± 5.0 vs 92.5 ± 1.7 % for incubation in Kreb's buffer, p < 0.05) and native HDL counteracted this inhibition (E max = 72.4 ± 4.8 vs 50.2 ± 5.0 % p < 0.05). At the opposite, oxidized HDL had no effect on oxidized LDL-induced inhibition on endothelium-dependent vasorelaxation (E max = 53.7 ± 4.8 vs 50.2 ± 5.0 %, NS). HDL oxidation is associated with a decreased ability of HDL to remove 7-oxysterols from oxidized LDL. In conclusion, these results show that oxidation of HDL induces the loss of their protective effect against endothelial dysfunction, which could promote atherosclerosis in diseases associated with increased oxidative stress.Heart and vessels. 07/2014;
Article: Changes in lipoprotein kinetics associated with type 2 diabetes affect the distribution of lipopolysaccharides among lipoproteins.[Show abstract] [Hide abstract]
ABSTRACT: Context: Lipopolysaccharides (LPS) are inflammatory components of the outer membrane of gram-negative bacteria, and in plasma, are mostly associated with lipoproteins. This association is thought to promote their catabolism while reducing their pro-inflammatory effects. Objectives: Our aim was to determine the impact of lipoprotein kinetics on plasma LPS distribution and how it may affect patients with type 2 diabetes [T2DM]. Design: We performed a kinetic study in 30 individuals (16 T2DM patients, 14 controls) and analyzed the impact of changes in lipoprotein kinetics on LPS distribution among lipoproteins. Results: Plasma LPS levels in T2DM patients were not different from those in controls, but LPS distribution in the two groups was different. Patients with T2DM had higher LPS-VLDL (31±7 vs. 22±11%, p=0.002), LPS-HDL (29±9 vs. 19±10%, p=0.015), free (non-lipoprotein bound) LPS (10±4 vs. 7±4%, p=0.043) and lower LPS-LDL (30±13 vs. 52±16%, p=0.001). In multivariable analysis, VLDL-LPS was associated with HDL-LPS (p<0.0001); LDL-LPS was associated with VLDL-LPS (p=0.004) and VLDL apoB100 catabolism (p=0.002); HDL-LPS was associated with free LPS (p<0.0001) and VLDL-LPS (p=0.033); free LPS was associated with HDL-LPS (p<0.0001). In a patient featuring dramatic decrease in VLDL catabolism due to apoA-V mutation, LDL-LPS was severely decreased (0.044 EU/ml vs. 0.788 EU/ml in controls). The difference between T2DM patients and controls for LDL-LPS fraction was no longer significant after controlling for VLDL apoB100 total FCR. Conclusions: Our data suggest that in humans, free LPS transfers first to HDL and then to VLDL whereas the LPS-bound LDL fraction is mainly derived from VLDL catabolism; the latter may hence represent a LPS catabolic pathway. T2DM patients show lower LDL-LPS secondary to reduced VLDL catabolism, which may represent an impaired catabolic pathway.The Journal of Clinical Endocrinology and Metabolism 04/2014; · 6.31 Impact Factor
Article: Glycation of Apolipoprotein C1 Impairs Its CETP Inhibitory Property: Pathophysiological Relevance in Patients With Type 1 and Type 2 Diabetes.[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE Apolipoprotein (apo)C1 is a potent physiological inhibitor of cholesteryl ester transfer protein (CETP). ApoC1 operates through its ability to modify the electrostatic charge at the lipoprotein surface. We aimed to determine whether the inhibitory ability of apoC1 is still effective in vivo in patients with diabetes and whether in vitro glycation of apoC1 influences its electrostatic charge and its CETP inhibitory effectRESEARCH DESIGN AND METHODS ApoC1 concentrations and CETP activity were measured in 70 type 1 diabetic (T1D) patients, 113 patients with type 2 diabetes, and 83 control subjects. The consequences of in vitro glycation by methylglyoxal on the electrostatic properties of apoC1 and on its inhibitory effect on CETP activity were studied. An isoelectric analysis of apoC1 was performed in patients with T1D and in normolipidemic-normoglycemic subjects.RESULTSAn independent negative correlation was found between CETP activity and apoC1 in control subjects but not in patients with diabetes. HbA1c was independently associated with CETP activity in T1D patients. In vitro glycation of apoC1 modified its electrostatic charge and abrogated its ability to inhibit CETP activity in a concentration-dependent manner. The isoelectric point of apoC1 in T1D patients was significantly lower than that in control subjects.CONCLUSIONS The ability of apoC1 to inhibit CETP activity is impaired in patients with diabetes. Glycation of apoC1 leads to a change in its electrostatic properties that might account, at least in part, for a loss of constitutive CETP inhibition and an increase in plasma CETP activity in patients with diabetes.Diabetes care 02/2014; · 7.74 Impact Factor
Article: Impact of liver disease severity and etiology on the occurrence of diabetes mellitus in patients with liver cirrhosis.[Show abstract] [Hide abstract]
ABSTRACT: The association between liver cirrhosis (LC) and diabetes mellitus (DM) is well known. However, the impact of the severity or etiology of LC on the occurrence of DM is relatively unknown. We aimed to determine the prevalence and clinical correlates of DM in a large cohort of patients with cirrhosis. A total of 1,068 patients with LC were included in this cross sectional study (CIRCE study). The diagnosis of cirrhosis irrespective of its etiology was based on histological confirmation by liver biopsy or, in the absence of biopsy, on typical clinical, morphological and biological data. Data related to the cirrhosis etiology: alcohol, viral markers of hepatitis B, C, iron load parameters and autoimmune markers were collected for each patient. Venous blood samples were taken in the morning after 12-h overnight fasting. There were 383 patients with cirrhosis associated with hepatocellular carcinoma (HCC). DM was found in 412 (39.7 %) patients. Patients with DM were older and more likely to be overweight and male, with a family history of DM and a diagnosis of HCC. DM was not associated with a history of stroke or myocardial infarction. Cirrhosis secondary to hepatitis infection was less strongly associated with DM than with NASH or alcoholic cirrhosis. The severity of LC was not associated with DM. In multivariate analysis, the factors associated with DM were age, BMI, a family history of DM, and statin use. There was a significant interaction between HCC and cirrhosis etiology for the risk of DM. Cirrhosis secondary to hepatitis was associated with a lesser presence of DM only in patients with HCC (interaction p = 0.0015). LC was strongly associated with DM, with around 40 % of diabetic patients. In the group of patients with LC without HCC, diabetes was not associated with the etiology of cirrhosis.Acta Diabetologica 12/2013; · 4.63 Impact Factor
Article: Body Fat Distribution and Adipokine Secretion Are Not Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus.[Show abstract] [Hide abstract]
ABSTRACT: Aims: The link between diabetic retinopathy (DR) and adipokines is controversial. Some studies suggest that visceral fat and adipokines could be additional risk factors for DR. The aim of this study was to determine the relationship between abdominal fat or adipokine secretion and DR in patients with type 2 diabetes mellitus (DM). Methods: A total of 179 patients with type 2 DM were included. Each patient underwent measurement of plasma adiponectin and leptin and an evaluation of body fat distribution (visceral and subcutaneous) with MRI. The severity of DR was evaluated according to the classification of the American Academy of Ophthalmology. Patients were classified in 3 groups: absence of DR, mild and moderate DR, and advanced DR (severe, proliferative and laser-treated DR). Results: There were no significant differences between the 3 groups for adiponectin, leptin and visceral or subcutaneous fat accumulation. Patients with DR had a mean duration of diabetes, serum creatinine concentration and percentage of macroalbuminuria significantly higher than patients without DR (p < 0.001, p = 0.003 and p < 0.001, respectively). Serum adiponectin increased with the diabetic nephropathy stage (p = 0.007). Conclusions: Our study suggests that body fat distribution and adipokine secretion are not associated with DR in patients with type 2 DM. © 2013 S. Karger AG, Basel.Ophthalmic Research 11/2013; 51(1):42-45. · 1.56 Impact Factor
Article: Preoperative adipocytokines as a predictor of surgical infection after colorectal surgery: a prospective survey.[Show abstract] [Hide abstract]
ABSTRACT: Infections are the leading cause of morbidity and mortality after colorectal surgery. Obesity is a well-known risk factor for wound infection, but it does not seem to increase the risk of other infectious complications. The aim of this study was to look for a relationship between the fatty tissue metabolism measured by adipocytokine levels and the risk of postoperative infection. Preoperative plasma levels of eight adipocytokines, cholesterol, triglycerides, insulin and C-reactive protein (CRP) were measured in consecutive patients undergoing elective colorectal surgery between June 2008 and June 2011. Information about epidemiological and clinical characteristics was obtained for each patient. All infections in the 30 days following surgery were recorded. Among the 174 patients included, 49 (28 %) presented with a postoperative infection: 41 surgical site infections and 8 other infections. Preoperative leptin, insulin and CRP were significantly higher in patients with postoperative infection (p = 0.025, p = 0.020 and p = 0.044, respectively), but only leptin was predictive of infection in multivariate analysis (odds ratio (OR) = 1.89, 95 % confidence interval (CI) 1.18-3.03, p = 0.008). The predictive value of leptin was slightly lower for surgical site infection (OR = 1.65, 95 % CI 1.06-2.55, p = 0.025). Leptin levels were independent of the other adipocytokine levels but not of the body mass index. Although markers of inflammation and insulin resistance are also related to the onset of surgical infection, leptin correlates more closely with the risk of infection than does any other factor. However, its effect could be partially mediated by the body mass index.International Journal of Colorectal Disease 10/2013; · 2.24 Impact Factor
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ABSTRACT: HDLs play a major role in vascular homeostasis. Their protective actions are mediated in part by their SR-BI specific receptor. HDLs glycation, huge phenomenon observed during diabetes mellitus lead to their increased catabolism, a decrease in the reverse transport of cholesterol, a loss of their antiinflammatory and antioxidant properties, particularly on oxidized LDL, abundant lipoparticules proatherogenic observed in chronic diseases. Endothelial dysfunction, a deleterious vascular phenomenon, observed in diabetes, is the clinical representation of these adverse effects of HDL glycation.Médecine des Maladies Métaboliques 10/2013; 7(5):431–436.
Article: Chronic Hyperinsulinemia Does Not Increase the Production Rate of High-Density Lipoprotein Apolipoprotein AI: Evidence From a Kinetic Study in Patients With Insulinoma.[Show abstract] [Hide abstract]
ABSTRACT: In vitro studies showed that insulin stimulates the production of apolipoprotein AI (apoAI). Thus, we hypothesized that chronic hyperinsulinemia could contribute to the increase in the production of high-density lipoprotein apoAI that is observed in metabolic syndrome. We performed an in vivo kinetic study with stable isotope in 7 patients with insulinoma who showed hyperinsulinemia but no insulin resistance, 8 patients with insulin resistance, and 16 controls. Insulinemia was 3.1× (P<0.01) higher in patients with insulinoma or insulin resistance than in controls in the fasting state and, respectively, 3.5× and 2.6× (P<0.05) higher in the fed state. The high-density lipoprotein apoAI pool size was smaller in patients with insulin resistance than in controls (49.3±5.4 versus 59.6±7.7 mg·kg(-1); P<0.01), whereas both the high-density lipoprotein apoAI fractional catabolic rate and the high-density lipoprotein apoAI production rate were higher (0.30±0.07 versus 0.20±0.04 pool·d(-1); P<0.0001 and 14.6±1.5 versus 11.5±1.9 mg·kg(-1)·d(-1); P<0.01, respectively). In contrast, no significant difference was observed for these parameters between patients with insulinoma and controls. In patients with insulinoma, the apoAI pool size tended to be greater than in patients with insulin resistance (56.3±8.6 versus 49.3±5.4 mg·kg(-1); P=0.078), whereas both the apoAI fractional catabolic rate and the production rate were lower (0.20±0.06 versus 0.30±0.07 pool·d(-1); P<0.01 and 11.1±1.6 versus 14.6±1.5 mg·kg(-1)·d(-1); P<0.01, respectively). The apoAI fractional catabolic rate was the only variable associated with the apoAI production rate in multivariate analysis and explained 80% of its variance. Chronic endogenous hyperinsulinemia does not induce any increase in the apoAI production rate, which seems to be more dependent on the apoAI fractional catabolic rate.Arteriosclerosis Thrombosis and Vascular Biology 08/2013; · 6.34 Impact Factor
Article: Deleterious effect of glycation on the ability of HDL to counteract the inhibitory effect of oxidized LDL on endothelium-dependent vasorelaxation.[Show abstract] [Hide abstract]
ABSTRACT: Contrary to HDL from normolipidaemic and normoglycaemic subjects, HDL from diabetic patients have lost their ability to reverse the inhibition of vasorelaxation induced by oxidized LDL. The aim of this study was to analyse the role of glycation, a major abnormality observed in diabetes, on the impairment of the vasorelaxant effect of HDL. HDL from healthy subjects, were glycated in vitro by incubation in glucose 200 mmolar for 3 days. Vasoreactivity was evaluated by the relaxation response to acetylcholine of rabbit aorta rings pre-contracted with noradrenaline, before and after two hours incubation with or without different lipoprotein fractions (Krebs'buffer; oxidized LDL; normal or glycated HDL alone and with oxidized LDL). The fructosamine/apolipoprotein AI ratio was significantly increased in glycated HDL compared to native HDL (53.63 ± 7.91 vs 18.51 ± 4.10 µmol/g; p < 0.05). Oxidized LDL inhibited endothelium-dependent vasodilation compared to Krebs'buffer (maximal relaxation (Emax) = 53.15 ± 6.50 vs 98.67 ± 2.07%, p < 0.001). Native HDL were able to counteract the oxidized LDL-induced inhibition of vasorelaxation (Emax = 76.93 ± 5.41 vs 53.15 ± 6.50%, p < 0.001). At the opposite, glycated HDL had no effect on oxidized LDL-induced inhibition on endothelium vasorelaxation compared to incubation with oxidized LDL alone (Emax = 52.98 ± 2.07 vs 53.15 ± 6.50%, NS). Glycation of HDL induces the loss of the ability of HDL to counteract the inhibitory effect of oxidized LDL on endothelium-dependent vasorelaxation, which is likely to contribute to the impairment of anti-atherogenic properties of HDL in diabetic patients. This article is protected by copyright. All rights reserved.Diabetes/Metabolism Research and Reviews 07/2013; · 2.97 Impact Factor
Article: Severe hypovitaminosisss D correlates with increased inflammatory markers in HIV infected patients.[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND: Even though it has been suggested that antiretroviral therapy has an impact on severe hypovitaminosis D (SHD) in HIV infected patients, it could be speculated that the different levels of residual inflammation on HAART (Highly Active Anti Retroviral Therapy) could contribute to SHD and aggravate bone catabolism in these patients. METHODS: A cross-sectional study was carried out in an unselected cohort of 263 HIV infected outpatients consulting during Spring 2010. Clinical examinations were performed and medical history, food habits, sun exposure and addictions were collected. Fasting blood samples were taken for immunological, virological, inflammation, endocrine and bone markers evaluations. RESULTS: Ninety-five (36%) patients had SHD. In univariate analysis, a significant and positive association was found between SHD and IL6 (p = 0.001), hsCRP (p = 0.04), increased serum C-Telopeptides X (CTX) (p = 0.005) and Parathyroid Hormon (PTH) (p < 0.0001) levels. In multivariate analysis, SHD deficiency correlated significantly with increased IL-6, high serum CTX levels, lower mean daily exposure to the sun, current or past smoking, hepatitis C, and functional status (falls), but not with the time spent on the current HAART (by specific drug or overall). CONCLUSIONS: SHD is frequent and correlates with inflammation in HIV infected patients. Since SHD is also associated with falls and increased bone catabolism, it may be of interest to take into account not only the type of antiretroviral therapy but also the residual inflammation on HAART in order to assess functional and bone risks. This finding also suggests that vitamin D supplementation may be beneficial in these HIV-infected patients.BMC Infectious Diseases 01/2013; 13(1):7. · 3.03 Impact Factor
Article: Validation of a reference method for total cholesterol measurement in human serum and assignation of reference values to proficiency testing samples.[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVES: Our objective was to develop a reference method to measure total cholesterol in human serum, in order to assign values and assess the accuracy of field methods in French clinical laboratories. DESIGN AND METHODS: A reference method based on gas chromatography coupled with mass spectrometry and isotope dilution (GC-IDMS) was developed and validated. It was then used to assign reference values to five frozen serum samples from voluntary Proficiency Testing schemes gathering 170 French clinical laboratories. Three peer groups were defined and bias against the reference method target value was calculated. RESULTS: Accuracy of the reference method was assessed against NIST SRM 1951b. Bias of the reference method was less than 0.5% and imprecision was less than 1.0%. Our study indicated that field methods tended to overestimate total cholesterol concentration, mean bias being +5.02% ± 1.02%. The most popular methods (phenolic chromogen with spectrophotometric detection, 80% of participants) exhibited the highest bias (peer group mean bias : +5.51 ± 1.24%). Neither these methods nor those using a non-phenolic chromogen with reflectometric detection (10% of participants, peer group mean bias : +4.20 ± 1.44 %) met NCEP recommendations according to which bias should be less than 3%. Only methods using a non phenolic chromogen with a spectrophotometric detection met these recommendations (10% of participants, peer group mean bias : +1.39 ± 2.75 %) CONCLUSIONS: As all three peer groups provided positively biased results, the consensus mean usually used to assess the trueness of routine methods is biased as well, which results in a erroneous estimation of method bias. Therefore, this study highlights the value added by reference method target values to assess trueness of field methods and monitor performance of clinical laboratories.Clinical biochemistry 12/2012; · 2.02 Impact Factor
Article: Retinol-Binding Protein 4 Is an Independent Factor Associated With Triglycerides and a Determinant of Very Low-Density Lipoprotein-Apolipoprotein B100 Catabolism in Type 2 Diabetes Mellitus.[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE: Retinol-binding protein 4 (rbp4) is an adipokine secreted by adipocytes and liver, whose levels are elevated in type 2 diabetes mellitus (T2DM). Plasma levels of rbp4 and triglycerides are strongly correlated in T2DM. However, we do not know whether this association is direct or indirect via liver fat content, and the link between rbp4 and triglyceride metabolism remains unknown. METHODS AND RESULTS: Liver fat measurement by proton spectroscopy was performed in 221 patients with T2DM, and an in vivo kinetic study with stable isotopes was carried out in 14 patients with T2DM. In multivariate analysis, triglycerides were associated positively with rbp4 (β=0.273, P<0.0001), apolipoprotein (apo) B (β=0.258, P<0.0001), and liver fat (β=0.191, P=0.002) and negatively with high-density lipoprotein cholesterol (β=-0.442, P<0.0001). rbp4 was correlated positively with apoB100 very-low-density lipoprotein (VLDL) pool (r=0.62, P=0.017) and negatively with VLDL-apoB100 total fractional catabolic rate (r=-0.66, P=0.001). In multivariate analysis, rbp4 (P=0.015), plasma triglycerides (P=0.024), and sex (P=0.026) were independently associated with VLDL-apoB100 total fractional catabolic rate. CONCLUSIONS: In T2DM, plasma rbp4 level is associated with plasma triglycerides, independently of liver fat content. There is a strong independent negative correlation between plasma rbp4 and VLDL-apoB100 total fractional catabolic rate. These data suggest that rbp4 may be involved in the pathophysiology of hypertriglyceridemia in T2DM by reducing VLDL catabolism.Arteriosclerosis Thrombosis and Vascular Biology 10/2012; · 6.34 Impact Factor
Article: Liver fat content is associated with an increase in cholesterol synthesis independent of statin therapy use in patients with type 2 diabetes.[Show abstract] [Hide abstract]
ABSTRACT: We investigated how liver fat content (LFC) influences cholesterol metabolism by quantifying liver fat using proton magnetic resonance spectroscopy and by measuring the serum concentrations of lathosterol, a marker of cholesterol synthesis, and sitosterol and campesterol, two markers of cholesterol absorption. We also evaluated whether this relationship could be modified by statin therapy. The study was conducted in 263 patients with type 2 diabetes, 137 of whom (52.0%) received statin therapy. RESULTS: One hundred and sixty-five patients (62.7%) had steatosis (LFC>5.5%). We performed specific analyses in patients without statin therapy and in patients treated with statin therapy. In both groups, the lathosterol to cholesterol ratio correlated positively with LFC, and in multivariate analysis, the lathosterol to cholesterol ratio was associated with LFC independently of age, gender and BMI. Sitosterol and campesterol concentrations were not associated with LFC. CONCLUSIONS: Our study suggests that in patients with type 2 diabetes, LFC is associated with an increase in cholesterol synthesis that is independent of obesity or diabetes mellitus. Statin therapy does not modify this relationship.Atherosclerosis 08/2012; 224(2):465-8. · 3.71 Impact Factor
Article: Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes.[Show abstract] [Hide abstract]
ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity, metabolic syndrome and type 2 diabetes. Although dietary fat contributes substantially to the accumulation of liver fat, the role of individual fatty acids in this accumulation is unclear. In this study, we set out to determine whether liver fat content (LFC), was associated with red blood cell fatty acid (RBC-FA) composition in people with type 2 diabetes. One hundred and sixty-two type 2 diabetic patients were included in this study. LFC was measured using (1)H-MR Spectroscopy. RBC-FA composition was measured by gas chromatography. One hundred and nine (67.2%) patients had steatosis. Patients with steatosis had a higher BMI (p = 0.0005), and higher plasma triglyceride levels (p = 0.009) than did patients without steatosis. We report a significant association between palmitic acid (16:0), palmitoleic acid (16:1n-7) concentrations and ratio of monounsaturated to saturated fatty acid (palmitoleic acid to palmitic acid) and higher liver fat content. Total polyunsaturated fatty acid (PUFA), homo-gamma-linolenic acid (20:3n-6), docosahexaenoic acid (22:6n-3), and arachidonic acid (20:4 n-6) were associated with lower LFC. Our data showed that an increased erythrocytes long-chain n-3 and n-6 fatty acids was associated with a lower prevalence of steatosis in patients with type 2 diabetes. These results suggest that n-3 and n-6 fatty acids supplementation could be a promising treatment for NAFLD in patients with type 2 diabetes.Clinical nutrition (Edinburgh, Scotland) 12/2011; 31(4):520-5. · 3.27 Impact Factor
Article: Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.[Show abstract] [Hide abstract]
ABSTRACT: The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI) are clinico-biological scores of steatosis validated in general or selected populations. Serum adiponectin (s-adiponectin) and retinol binding protein 4 (s-RBP4) are adipokines that could predict liver steatosis. We investigated whether the Steatotest, FLI, HSI, s-adiponectin and s-RBP4 could be valid predictors of liver steatosis in type-2 diabetic (T2D) patients. We enrolled 220 consecutive T2D patients. Reference standard was 3.0 T (1)H-MR spectroscopy (corrected for T1 and T2 decays). Intraclass correlation coefficients (ICCs), Kappa statistic measures of agreement, receiver operating characteristic (ROC) curves were assessed. Median liver fat content was 91 mg triglyceride/g liver tissue (range: 0-392). ICCs among the Steatotest, FLI, HSI, s-adiponectin, s-RBP4 and spectroscopy were low: 0.384, 0.281, 0.087, -0.297 and 0.048. Agreement between scores and spectroscopy was poor (Kappa range: 0.042-0.281). The areas under the ROC curves were low: 0.674, 0.647, 0.637, 0.616 and 0.540. S-adiponectin and s-RBP4 levels were strongly related to the presence of diabetic nephropathy (P = 0.0037 and P = 0.004; Mann-Whitney). The SteatoTest, FLI, HSI, s-adiponectin, s-RBP4 are not valid predictors of steatosis in T2D patients. Clino-biological markers cannot replace (1)H-MR spectroscopy for the assessment of liver fat in this population. (1) H-MR spectrosopy can reliably estimate the weight fraction of liver steatosis. Type-2 diabetes provides an interesting model for assessing liver steatosis. Clinico-biological markers seem to be invalid predictors for steatosis in type-2 diabetes.European Radiology 11/2011; 22(4):855-63. · 4.34 Impact Factor
Article: Le point sur les différentes méthodes pour déterminer le cholestérol-LDL: Methods for LDL-cholesterol determination: An update[Show abstract] [Hide abstract]
ABSTRACT: The serum concentration of LDL-cholesterol (LDL-C) is a key parameter for the evaluation of cardiovascular risk. The first routine method allowing the calculation of LDL-C was the Friedewald formula which estimates LDL-C from the concentrations of total cholesterol, HDL-cholesterol and triglycerides. Triglyceridemia above 2 g/L is associated with a risk of inducing a negative bias superior to 10%, and the risk is increasing with triglyceridemia increases. Thus, in clinical practice, the Friedewald formula is not used when triglyceridemia is above 3.4 g/L. Direct methods for LDL-C measurement, based on different principles, are now available. These methods are satisfactory on the whole, but can be associated with biases compared to the reference method (β-quantification) and they do not allow a better evaluation of cardiovascular risk than the Friedewald formula for patients with a triglyceridemia between 2 and 4 g/L. In that regard, patients affected with type 2 diabetes may constitute an exception, but this conclusion has been drawn from small groups of patients and need further confirmation. These methods are particularly useful when the Friedewald formula can not be used due to triglycerides above 3.4 g/L. However when triglycerides further increase (above 7 g/L for some methods; above higher values for others), they also interfere with direct methods that can not be used anymore.Médecine des Maladies Métaboliques 09/2011; 5(4):420–423.
Article: Lack of association between plasma PCSK9 and LDL-apoB100 catabolism in patients with uncontrolled type 2 diabetes.[Show abstract] [Hide abstract]
ABSTRACT: Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is a post-transcriptional inhibitor of LDL-receptor. In non-diabetic men, plasma PCSK9 levels were found to be inversely correlated with low-density lipoprotein (LDL) apolipoprotein B100 (apoB) fractional catabolic rate (FCR). Here, we aimed to determine the effect of type 2 diabetes on the association between plasma PCSK9 and FCR of LDL. A kinetic study of LDL-apoB100, using stable isotopes, was performed in 38 individuals (20 men, 18 women) including 23 non-diabetic normolipidemic subjects and 15 patients with type 2 diabetes. In the non-diabetic group, plasma PCSK9 was positively correlated with LDL-C (r=0.64, p=0.001), apoB (r=0.67, p<0.001), and inversely correlated with LDL-apoB FCR (r=-0.61, p=0.002). In contrast, in type 2 diabetic patients, plasma PCSK9 was not associated with LDL-C, apoB and LDL-apoB FCR. However, the lack of association between PCSK9 and LDL-apoB FCR seemed to be limited to the patients with "uncontrolled" diabetes (HbA1c>7%) since a borderline significant negative correlation between PCSK9 and LDL FCR (r=-0.70, p=0.08) was retrieved in patients with HbA1c≤7%. In multivariate analysis, LDL-apoB FCR was independently associated with PCSK9 (p=0.001) and fasting glycaemia (log) (p=0.030) in the non-diabetic population and with PCSK9 (p=0.040) and HbA1c (p=0.029) in diabetic patients. Our data indicate that both PCSK9 and glycaemia are independent factors influencing LDL catabolism. Plasma PCSK9 influences significantly the catabolism of LDL-apoB100 in individuals without diabetes, but not in patients with uncontrolled type 2 diabetes. Thus, the influence of diabetes on LDL-apoB FCR catabolism may overwhelm the influence of PCSK9.Atherosclerosis 07/2011; 219(1):342-8. · 3.71 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Recently, it has been shown that an allele in the adiponutrin (PNPLA3) gene was strongly associated with increased liver fat content (LFC) and liver fibrosis independent of visceral adiposity and insulin resistance. In this study, we set out to determine whether the PNPLA3 rs738409 polymorphism was associated with liver fibrosis in unselected patients with type 2 diabetes. Two hundred and thirty-four patients with type 2 diabetes were included in this study. LFC was evaluated using (1) H-MR spectroscopy; fibrosis was measured using the non-invasive FibroTest(®). Advanced liver fibrosis (stage F2 or above) was observed in 10.2% of the patients while 149 (63.6%) patients had steatosis. The prevalence of steatosis and fibrosis was higher in minor G allele carriers than that in C allele homozygote carriers (70.3 vs 57.1%; P=0.04 and 14.7 vs 7.5%; P=0.07 respectively). In multivariate analysis, the predictive variables for advanced liver fibrosis were age (≥60) (P=0.005), sex (female) (P=0.004) and rs 738409 PNPLA3 polymorphism (P=0.01); body mass index (BMI) and LFC were not associated with liver fibrosis. This study confirms that in patients with type 2 diabetes who were not selected for liver abnormalities, liver fibrosis was related to the rs738409 polymorphism independent of BMI or LFC.Liver international: official journal of the International Association for the Study of the Liver 06/2011; 31(9):1332-6. · 3.87 Impact Factor
Top Journals
Centre Hospitalier Universitaire de Dijon
Dijon, Bourgogne, France
- Endocrinology, Diabetes and Metabolic Diseases Service
French Institute of Health and Medical Research
Lutetia Parisorum, Île-de-France, France
- Center of Medicine, Sciences, Health, Mental Health and Health Policy CERMES 3
Unité Inserm U1077Caen, Lower Normandy, France
University of BurgundyDijon, Bourgogne, France
Hôpital Universitaire NeckerLutetia Parisorum, Île-de-France, France

subset: commoncrawl


text:
Diners Drive-ins and Dives
- alarash May 21, 2014 05:53 PM
After years of being a fan and trying to visit the places featured on this show, Guy Fieri stuffing his face is finally getting on my nerves.
"Mmmmmmm, that ___ is on point!"
"That's one of the best ____ I've eaten all year"
If I *am* watching the show, my favorite thing to do is watch the chef watch Guy Fieri stuff his face. I always get the feeling Fieri's team does not pay for the food they're eating, or at least it seems so by the way the chefs tend to wince and grimace watching him eat it. Or at least that's my interpretation of what's going on.
In the old country they would call such people "moft-khor," meaning someone who "eats-for-free," a derogatory term implying the person is a parasite.
Of course, the chef might be grimacing from uncertainty, nervous about how he'll react to the food; but they shouldn't be nervous, as his reviews are uniformly spectacular. Also, it seems silly for the chef to be concerned about the cost of the food in comparison to the great publicity the show provides.... but I still get the vibe these chefs are a little annoyed.
I have yet to see many chefs cheer him on to eat more, or look thrilled as he's stuffing his face. Has anyone else noticed this, or am I alone in this observation?
Hi, alarash:
Nope, I think you nailed it. I'm amused that GF always seems to act like the chef and he are kindred souls, and the chefs all act like they can't wait for him to scuttle off.
I think the show's single virtue is that it shows places that exist.
re: kaleokahu
that is the ONLY point of the show, to highlight places that are off the general radar, now if it could just be done without Guy...
re: hill food
I've become more accepting of the show and Guy as time has passed, but my complaint is how rare an actual diner, drive in or dive is actually shown. More often than not it's a middle-class roadhouse style big food family joint with a specialty, which is nice but not exactly off the beaten path.
re: ennuisans
I don't believe the point of the show is to feature eateries that are off the beaten path.
re: John E.
Maybe there's a better way of phrasing it. Places with cult popularity?
There is, for instance, in the St Louis area, a place called Carl's Drive In. They serve home made IBC Root Beer from the original recipe and people seem to like their tamales. There is only counter seating that might fit 20 people tops, and the parking lot is packed from open to close. But this is not going to be on the show.
Andrew Zimmern did a great job showcasing places in St Louis with little visibility in just one show. Guy probably has as well, but with far less consistency. And I have yet to see a dive.
re: ennuisans
Why do you believe Carl's Drive In won't ever make it on D, D, & D?
Al's Breakfast in Minneapolis certainly qualifies as a dive. (It's a "dive aspiring to be a diner.") It's been on D, D, & D twice. (Of course many on the production team are from the Twin Cities.)
re: John E.
I believe that Carl's won't be on DDD (or The Buttery, or South City Diner) because even though they are well known locally, their food is just average in itself. They are "made" good by cultural and social relationships, but the food is not something Guy is going to moan over.
re: ennuisans
D, D, & D. did a shoot at a drive-in in Cloquet, Minnesota that really has just decent burgers, fries, and chili.
I do know that the criteria for getting on the show is good food that is made on site with nothing coming from Sysco and the like.
re: ennuisans
Reminds of the complaints about a certain Oklahoma woman who isn't much of a pioneer, and a Connecticut cook who wears shoes (and isn't a countess)!
re: hill food
Hi, hill:
Really? My sense is that the places they feature are on EVERYBODY'S radar in the general area. It appears to me as more of a local hit parade than showing hidden gems.
I think the show easily *could* be done by just about anyone (I can gorge and intone "Mmmmmmmmmm, Man!" just like Guy, maybe better). Or, it could be done with no one but patrons who're familiar with the joint's food, in sort of a guided YouTube style. Or a disembodied AI voiceover added in postproduction, I don't know.
Hell, any of the fired Chow people could do a better job than GF, IMO.
re: kaleokahu
in the areas I've lived in - yes they are already known and either loved or reviled, but for a casual visitor, sometimes they are unheard of.
I prefer your idea, whenever I hear "It's Time For..." I mutter 'nope, not for me it ain't' and change the channel.
re: kaleokahu
There are tourists who specifically search out the places featured on these shows when they travel to new locations. So they do get publicity for being on the show.
re: kaleokahu
GF makes about $5mm per year.
I don't.
Love him or hate him, he has a personality that people like enough to watch him.
He is an entertainer and I know I couldn't do what he does. I doubt that most CHs could either.
If I could, I probably would.
re: kaleokahu
There is a PBS show called "Check Please xxx" that is produced in several cities. I think it originated in Chicago, we have our own version in the SF Bay Area. Anyone (regular people) can nominate a restaurant and the producers select three per episode. The three panel members visit each restaurant anonymously with their own family or friends and then they tape a panel discussion. They also tape a segment with the restaurant chef or owners after they have been selected for the show. It's quite entertaining and everyone does not always agree on the restaurants.
re: libgirl2
Hi Kaleo,
I didn't know Seattle had a version of the show. I will check it out online. Our SF station (kqed.org) puts all the shows online once they have aired.
Hi libgirl2, I can imagine with the Chicago metro area being so huge that it would be hard to cover every where. But you and your friends could start nominating places.
In the SF Bay Area we get a pretty good range of restaurants, from San Jose to the Napa Valley.
re: hill food
re: CindyJ
That would be awesome
re: rozz01
I'd watch the hell out of that. The Sterns are like the proto-Guy
re: CindyJ
Has anyone seen video of the Sterns? I hear them regularly on The Splendid Table. And last weekend I caught the tail end of a clip of them on Rick Steve's travel show. But I don't know how they'd come across on video. Sometimes people are better with just the audio.
From what I've heard, a place shown on DDD is in for a huge increase in business. HUGE.
The cost of food to feed Fieri is indeed dirt cheap compared to the value of the advertising.
I'm not a particular fan of the show, but if I had a restaurant I'd be ecstatic to have him drip televised juices on my floor.
re: sal_acid
Hi, Sal:
Sure, there's no such thing as bad publicity (what the French call "Succès de Scandale"). It made P.T. Barnum, Mae West, Stravinsky, Manet, and Paris Hilton, among others.
To paraphrase Oscar Wilde, the only dive worse than one being talked about is one not being talked about.
re: sal_acid
We DO own a restaurant and I would be extremely reluctant to have us featured on DDD or any other food show. According to the SBA, a major reason for business failure is growing too rapidly. We're already operating at maximum capacity and do not have room to expand inside or out. I like free publicity as well as anyone but you CAN have too much of a good thing.
re: elegraph
Is your restaurant quite profitable? If so, I can understand your point.
If you cannot handle more business while making a profit, I can understand why you would be reluctant to appear on D, D, & D.
re: elegraph
I am familiar with a local bar/restaurant that was on DDD. I first heard about them on my regional Chowhound board.
This is a small place, tiny kitchen and when we first started going there it was usually just the husband (chef) and wife (bartending) owners and maybe one or two other employees. Pretty great food and a fun atmosphere.
I don't know about profits but I know that things changed a lot after DDD. They had to scramble to get more staff, add more seating. And they got a lot unfavorable comments on Y**p about slow service and that people's expectations from the show were not being met. Apparently some people were surprised that a place that was advertised as a dive bar was actually kind of divey.
The good news is that they are still in business, doing what they do, after a few years.
I guess ill disagree with everyone. I think the cooks or chefs are just nervous about how he is going to react to the food. I think there thinking nothing of the cost.
Guy seems to really love food and to me seems to be one of the only ones who actually tastes the food before he goes 'hmm hmm'... A pet peeve of mine if one someone has barley bit down and there already rolling there eyes at how good something is.
You can tell when Guy dosnt like something as he usually immediately starts talks about the ingredients. Not always but a lot.
re: daislander
Where I live, in Cincinnati, the places Guy has featured have had varying degrees of renown. Of the three I can think of, I'd been to Blue Ash Chili several times, but never to Terry's Turf Club or Virgil's Café (across the river in Bellevue, KY. And Virgil's is now one of our favorite places.
re: daislander
I read an article about the show in FN magazine. Apparently he does not meet with the chefs before filming because he prefers to authentically react to the Chef and the food. He said even if he doesn't like what he's eating, he will try to find something positive to say about it, very fresh or you can really taste the whatever ingredient. He claims he will not lie and say something is fantastic if it is not. He also tells the chef/owners to print up shirts or bumper stickers whatever the gimmick because after the show airs they may think they'll be prepared for the bump in business but they have no clue.
I don't watch DDD very often but I found the article interesting.
re: jpc8015
The DDD places that I've been to have definitely not been higher-end - they've exemplified at least one of the D's.
Its not the cost - being featured on a show like that will bring in a lot of business to an establishment - one bar-restaurant in my neighborhood was featured on that show years ago and still people from outside the area bring it up - its not even that great a place IMHO
Not such a fan of the personality but it is nice to see features on local restaurants and how they make stuff
it is overwhelmingly positive - that's sort of the point I guess though - if he said "this meatball sandwich is good but the one from that place in Boston kicked its butt" I think the chefs would wince more.
re: sandylc
They don't close, but they do pause. It's important to show customers eating and enjoying the food.
If a restaurant is featured on D., D., & D., they can expect their sales to increase quite a bit. Before the change in producers, they even sent out the production team without G.F. and shot at places where Ferry never even ate the food. I was not a fan of that part of the series.
By the way, early on they did a shoot at Emily's Lebanese Deli in NE Minneapolis. I was not impressed with their food
I have eaten at a few of the places where D., D., & D. has been to, a few in the Twin Cities and a few in Arizona. I have not really been all that thrilled with any of them. I think the expectations may have been too high. It's been a few years since I've been to any of the destinations.
My biggest complaint about DDD is the apostrophe on "Drive-ins' ".
And spell check even thinks it's O.K.
re: sandylc
I"m chagrined that I had not noticed the stray apostrophe in the logo. That is quite embarrassing that it was not caught and has never been corrected.
re: John E.
These kinds of things leap out at me and then chew on me. I need to get a life, clearly.
Now how can I make lots of money with this "talent"?
re: sandylc
Nice catch. Now, if we can get people to stop talking in the subjective, such as, "The host of DDD would be Guy Fieri." No, it's "The host of DDD IS Guy Fierei." I hear it every day in many situations. Yes, I share a certain "talent" with you. Maybe our heads will explode in tandem some day.
re: James Cristinian
re: kaleokahu
re: James Cristinian
re: James Cristinian
re: SimSportPlyr
I'm really confused. See if you can translate this.
I've been to one place Guy visited, T-Bone Tom's in Kemah, Texas. I would not classify it as a diner, drive-in, or dive. I've been before and after the show and prefer the fried shrimp and oysters. It's very close to Galveston Bay and they have a water marker inside courtesy of Hurricane Ike in 2008, 6 feet or so.
re: James Cristinian
The definition at that link is difficult to understand for anyone who doesn't already know what subjunctive means, because it's terse (because it is a dictionary definition). It takes a lot more verbiage to explain subjunctive, for example:
The example, "The host of DDD would be Guy Fieri." reads as though it is conditional ("The host of DDD would be Guy Fieri if.....") although it isn't, of course. Actually, I don't know how to classify that sentence. Maybe the classification is: grammatically incorrect (or, politically correctly: "non-standard English").
Anyhow, I thought you may have meant 'subjunctive' rather than 'subjective', although I don't think the example uses subjunctive. Examples of subjunctive:
"If Guy Fieri were host of DDD...."
"If I were Guy Fieri, I would not rave about every dish I tried."
re: SimSportPlyr
Yes, what I said about should be followed generally by a but, as in, "The host of DDD would be Guy, but it's not. The producers decided upon SimSportPlyr."
re: James Cristinian
"...producers decided upon SimSportPlyr"
I'd watch that.
have to say it, don't care for Guy and that name DDD just sounds like a bra size so I always thought he had man boobs
I will admit to liking the show. Most of the episodes I've watched he seems to be having a good times, and the chefs seem to be having a good time as well. I particularly like when he has the chef cook the dish so you can see the amount of ingredients and time that goes into some of these things. I also like that he is upfront about hating eggs. Everyone has dislikes, I'd rather he be honest about it than getting a big bite of egg and going yum yum


text:
University of Redlands > Academics >
College of Arts & Sciences >
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Key things you need to know aboutDr. Khawaja:
Dr. Khawaja's Experience
Research training, expertise and qualifications
Dr. Khawaja's Specialties
- Cardiology
- View 1 specialty and 2 board certifications
Procedures Dr. Khawaja Performs
- Cardiac Imaging
- Cardiac Myocardial Perfusion Imaging
- See all 5 procedures
Conditions Dr. Khawaja Treats
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- See all 20 conditions
More About Dr. Khawaja's Background
Hospital Quality
The right hospital is as important as the right doctor
- Sebastian River Medical Center
- 13695 Us Highway 1
- Sebastian, FL 32958
9 Facts About Hospital Quality
Patients' risk of dying during a hospital stay for heart bypass surgery could be 85.2% lower, on average, at a hospital rated 5 stars compared to a hospital rated 1 star for that procedure. Choosing the right hospital is critical to your health. View Slideshow
Patient Satisfaction
Patients' feedback on their experience with Dr. Khawaja
Likelihood of recommending Dr. Khawaja to family and friends is 4.2 out of 5 5 1 9
See More Survey Results
8 Facts About Patient Satisfaction Surveys
Patient satisfaction surveys provide a standardized way of reporting about healthcare experiences. But there can be more than meets the eye when reviewing scores. Here's what you should know
Appointments & Offices
Check insurance plans, locations and make an appointment
- Coastal Cardiovascular Assocs
- Coastal Cardiovascular Assocs
- 7754 Bay St Ste 6
- Sebastian, FL 32958
- Coastal Cardio Associates
- Coastal Cardio Associates
- 7754 Bay St Ste 7
- Sebastian, FL 32958
7 Tips to Prepare for Your Appointment
The key to a successful appointment is communication. To get the most out of your visit, prepare ahead of time so you can lead the conversation with your doctor. These 7 tips will get you ready
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Favorite Shows?
Find a Conversation
Favorite Shows?
|Mon, 08-22-2011 - 12:34pm
Landon is in love with Blue's Clues.
|Mon, 08-22-2011 - 2:14pm
I will preface this by saying my kids watch WAY too much tv, and I know this.
|Tue, 08-23-2011 - 11:00am
I've never even heard of Bubble Guppies or Team Umizoomi! They sound like fun shows, though!
Oh, I forgot that Landon likes to watch Caliou on occasion as well. I really cannot stand that show! There is far too much whining going on for my taste. ;)
Oh, I forgot that Landon likes to watch Caliou on occasion as well. I really cannot stand that show! There is far too much whining going on for my taste. ;)
|Tue, 08-23-2011 - 11:11am
Emma likes Caliou quite a bit also, but we don't get to it too often, I think its on at the same time as Dora or Blues Clues now. Bubble Guppies is new, its the cutest show, they do a lot of songs about things, like build me a building, an episode about construction and the tools that are used. Team Umizoomi is a show mostly about math, they "save the day" of the little preschool child by doing tasks that usualling involve measuring, shapes, and math. THey have a lot of stuff on Nick Jr.'s website that are helpful also. I am thinking of getting the Team Umizoomi backpack set for the 4 year old for christmas, it has a bunch of math games and worksheets to do it in.
|Tue, 08-23-2011 - 12:31pm
Thomas, thomas thomas. Maybe some Bob the builder, and Little People. That's it for us! They also like Max and Ruby but we don't get that channel
|Wed, 08-24-2011 - 9:53am
Those both sound like super cute shows. We'll have to check out the Nick Jr website. We got rid of cable TV last October so we watch whatever we can find on Netflix right now. I always forget to see what can be watched online!
|Wed, 08-24-2011 - 9:54am
LOL! It's weird because my boys were never into Thomas at all but it seems like a lot of kiddos just love it! Landon has taken a small interest but he's not addicted... yet! As for Max and Ruby, I still catch my older boys watching it (but don't tell them I told you. LOL!).
|Wed, 08-24-2011 - 11:41am
You can watch both shows on Nick Jr. 's website. I have thought about losing cable, but can't give up my football during football season and don't care to watch the games online. We also have my ipad that I download tv shows too and will put it on in the car like a DVD player, it workes well enough for us.
|Tue, 08-30-2011 - 9:59am
My 2 year old daughter is ALL about Toopy and Binoo!!
She asks for it the second we get home from daycare!!
< Andy
|Tue, 09-06-2011 - 9:43pm
I'm not a bad mom, I promise, but TV is always on in the background. Maddie my almost 4 year old will even watch Grey's Anatomy during the day on occasion (but she can tell you all about different medical terms, which is pretty good). Anyway, we watch Bubble Guppies sometimes (they love the Clambulance episode with Avi), Peppa Pig every day, Fresh Beat Band, and Max and Ruby. They will every so often try to change it up.


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Dave Barnes
What We Want, What We Get - CD
Dave BarnesWhat We Want, What We Get showcases Barnes at his best yet as he explores a range of texture and melodies with songs expressing a wide range of emotions. The most accessible and inspiring of all of his projects, he explains, "When I decided to make this record I really... Learn More
Stories to Tell
Dave BarnesSomething a little different. Those are the words used to describe Dave Barnes newest CD. Making a departure from his usual style, the Grammy nominee includes more synth sounds, soulful vocals and orchestral accents, giving Stories to Tell a lot of fun and a little unexpecte... Learn More
A December to Remember
Dave Barnes$9.99Add Your ReviewDave Barnes releases his second Christmas album, a blend of holiday classics and originals. With jazz influences and a touch of pop, each song captures the heart of Christmas.Track Listing:Better Than Christmas Day So, Santa It's the Most Wonderful Time of the Year In Bet... Learn More


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NO + 15.5....I know this is a rough time of year to bet anything significant on the NBA. But I believe this situation and line warrant that. I know that NO is without their best players for the rest of the season. But how motivated is OKC going to be to win this game by 16+ points? They know they can cruise and win this game by 8-10 points, and that's what i think they will do. Coming off a huge win against LAC, and coming off a road trip. This is the perfect spot for me to fade this big number.....BOL
Didn't really look into this game with the number and it being the pelicans, but after reading your write up and reasoning I like the play.... Esp after that big win vs the clipps, I can see a let down BOL
2014 MLB posted plays 43-46-3 no plays over -140 (records updated weekly, grinding all season)
2014 NFL weekly Best Five - Against The Spread- 32-26-1
2014 CFB posted plays against the spread 9-4
2014 NBA posted plays 10-9
2014 college bball posted plays 0-2
Bol tonight West Coast.. pelicans have made me alot of money this year.. hope they cash for you... cant wait for the playoffs
Tom Manton: NBA/NFL/CFB Weekly Pass | NBA Season SubscriptionSunday: Full NFL Card- Chargers -5.5 (2 unit) Broncos -6 Seahawks -7Twitter: @TMant1544
Thnks fellas BOL and lets ca$h


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The following item illustrates the aim behind inciting passions and fuelling tensions: to enact more legislation that is self-serving and destroys the standards and due process established by a civil society based on the Rule of Law, as the British government is planning to do. 389 more words
Tags » Freedom Of Conscience
When Rights Conflict, part 2: How to Determine which Rights are Natural
The question of how to determine which rights are natural seems difficult to answer conclusively. My attempt to establishing some guiding principles here are not informed by a proper education in law or moral philosophy, so I expect and invite critique. 352 more words
Harper's self-serving anti-terrorist agenda: When does a group or an individual pose a danger to society?
By PAULINE EASTON
(Oct. 25) – IT IS CLEAR that there are a lot of people across the country who are very disturbed by recent events. 1,545 more words
City of Houston demands that pastors hand over all sermons on homosexuality
Fox News has the story and the backstory, too.
451 more words
The city of Houston has issued subpoenas demanding a group of pastors turn over any sermons dealing with homosexuality, gender identity or Annise Parker, the city's first openly lesbian mayor.
Can we ban Religious Conversions? A Response to Jaideep Prabhu
I couldn't help but notice the irony in Jaideep A Prabhu's strong critique of Nehru's political imagination, when my quick search informs me that he is the Jawaharlal Nehru Professor of Business and Enterprise at the Judge Business School at the University of Cambridge. 743 more words
WWI and the Adventist Church
The Seventh-day Adventist Church in the United Kingdom has compiled information regarding how Adventists in the region responded to World War One–WWI and the Adventist Church… 181 more words
Government Enforcement of Morality
Comment posted on the Odessa American, 8/26/2013
Amen! I am amongst a growing group of Americans who are fighting for the day when the police power of the government is not used to force conformity to a particular set of values. 63 more words


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SAN FRANCISCO – For the third time in four games, the St. Louis Cardinals have had to change their regular lineup because of an injury.
Left fielder Matt Holliday, who led the club with 102 RBI in the regular season and was second with 27 home runs, was scratched from Game 6 of the National League Championship Series less than an hour before it began because of lower-back tightness.
Matt Carpenter, who became the Game 3 hero by hitting a two-run homer after replacing the injured Carlos Beltran, took over in Holliday's place. Manager Mike Matheny juggled the lineup as a response to Holliday's ailment, inserting Carpenter in the No. 2 spot at first base and moving Beltran down to third.
PREVIEW: Cardinals vs. Giants
Cleanup hitter Allen Craig remained in that slot but shifted from first base to left field.
Holliday, the focus of attention in the aftermath of his takeout slide that injured San Francisco Giants second baseman Marco Scutaro in Game 2, is batting .190 with two RBI in the series.
For the postseason, Holliday is at .222 with a homer and seven RBI.
A link has been posted to your Facebook feed.


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Town Square
Sort by: Most recent topic/comment Most viewed Most comments
Navigation tip: Clicking on any category label will display all recent posts in that category
AROUND TOWNCouncil approves $34 million spending plan
The $34 million spending plan calls for $26.1 million budgeted for town expenses, $2 million for the town as [http://www.danvilleexpress.com/news/show_story.php?id=7000&approved=yes...Original post made on Jun. 27, 2012
Last comment by Greg, on Jun 28, 2012 at 3:17 pm | 2 comments | 1533 Views
COMMENTS ON STORIESEBMUD water rate increases to take effect
Water rates for Danville and most of San Ramon will increase by 9.5% starting Tuesday (July 1), the last of back-to-back...Original post made on Jul. 1, 2014
Last comment by fairness, on Aug 26, 2014 at 10:27 am | 16 comments | 1533 Views
COMMENTS ON STORIESMeasure D fails; Supervisor Piepho gets another term
Measure D supporters were glum as Superintendent Rob Kessler spoke to them Tuesday night shortly after 9 p.m., thanking them...Original post made on Jun. 4, 2008
Last comment by Claire, on Jun 5, 2008 at 9:18 am | 2 comments | 1532 Views
SCHOOLS & KIDS5th Annual Benefit Luncheon
February 19th, 2009, the Auxiliary for the Child Abuse Prevention Council of Contra Costa County (CAPC) will hold their 5th...Original post made by Child Abuse Prevention Council of Contra Costa County on Jan. 7, 2009
There are no comments yet. 1532 Views
COMMENTS ON STORIESFresh and Easy plans 2011 opening in Danville
It took longer than expected, but Fresh and Easy plans to open in Danville in the early part of next year. Company spokesman...Original post made on Nov. 15, 2010
Last comment by collins, on Nov 15, 2010 at 11:50 am | 1 comment | 1532 Views
SPORTSWeather closes Hap Magee Canine Corral
Canines used to leash-free romps at the Canine Corral at Hap Magee Ranch Park will have to travel a little further. Each...Original post made on Nov. 22, 2010
Last comment by askidoo, on Dec 2, 2010 at 10:38 pm | 3 comments | 1532 Views
COMMENTS ON STORIESAlamo could make it as a town, says financial report
A Comprehensive Fiscal Analysis conducted by the engineering firm Winzler and Kelly found that the town of Alamo would have...Original post made on Jul. 30, 2008
Last comment by Rachel Wells, on Jul 31, 2008 at 5:29 pm | 2 comments | 1531 Views
AROUND TOWNMount Diablo fire 90 percent contained; investigators suspect human activity sparked blaze
Crews are taming the Morgan Fire, which has charred an estimated 3,133 acres in and around Mount Diablo State Park since...Original post made on Sep. 13, 2013
Last comment by Huh?, on Sep 13, 2013 at 11:02 am | 2 comments | 1531 Views
COMMENTS ON STORIESPolitical vandals
Bob Myhre, an opponent of incorporating Alamo and a proponent of a municipal advisory committee, shows the sign that was...Original post made on Sep. 12, 2008
Last comment by Steve Mick, on Sep 14, 2008 at 5:53 pm | 2 comments | 1530 Views
CRIMES & INCIDENTSThree years later: Tragic tale of greed and murder ends with son's conviction
The case has all the elements of a made-for-TV movie: greed, lust, brutality and a man whose lack of emotion made him the...Original post made on Apr. 1, 2011
Last comment by Longtime Resident, on Nov 22, 2014 at 12:27 pm | 3 comments | 1530 Views
CRIMES & INCIDENTSDriver who killed Dublin cyclist charged with murder
The Pleasanton teen who ran down and killed a bicyclist on Foothill Road on June 9 had his charges elevated to murder and...Original post made on Aug. 14, 2013
Last comment by Pedal Power, on Aug 19, 2013 at 11:59 pm | 11 comments | 1530 Views
AROUND TOWNHome ball field goes back to the drawing board
The Lowe family is still trying to get OKs for their private baseball field for work that was done without permits in 2007....Original post made on Feb. 13, 2009
Last comment by Alamoana, on Feb 21, 2009 at 3:15 pm | 7 comments | 1529 Views
COMMENTS ON STORIESSRVUSD Board Profile: John D. Lane IV
Four are vying for three spots in the San Ramon Valley Unified School District Board of Education. While it appears that...Original post made on Oct. 20, 2010
Last comment by Tom Cushing, on Oct 28, 2010 at 3:43 pm | 26 comments | 1529 Views
COMMENTS ON STORIESKeep Danville incumbents
Four candidates are running for three seats on the Danville Town Council: incumbents Newell Arnerich, Candace Anderson and...Original post made on Oct. 30, 2008
Last comment by moron with an i, on Oct 30, 2008 at 4:11 pm | 1 comment | 1528 Views
AROUND TOWNLAFCo Incorporation Studies: when do we pay the bill?
Diablo Vista (Alamo) region neighbors will donate $25 or more per residence to the Alamo Community Foundation, www.alamocommunity.org,...Original post made by Rachel Wells on Jul. 9, 2008
Last comment by Beth Rauch, on Jul 11, 2008 at 1:32 pm | 1 comment | 1527 Views
COMMENTS ON STORIESHartz Avenue institution closing after 30 years
La Ultima, the New Mexican restaurant which has occupied a prime Hartz Avenue locale for 32 years, will officially shut its...Original post made on Apr. 26, 2011
Last comment by Carol, on May 6, 2011 at 4:01 pm | 5 comments | 1527 Views
SCHOOLS & KIDSLTTE - Opposition to Measure C
Dear Dolores, It is fascinating that opposition to Measure C can be labeled as Michael James Aratas opposition. The...Original post made by Community courtesy on Apr. 10, 2009
Last comment by Rick, on Apr 28, 2009 at 6:11 pm | 2 comments | 1526 Views
COMMENTS ON STORIESMark Curtis takes news anchor job in Rhode Island
Veteran newsman Mark Curtis, a Danville resident and former news anchor for KTVU-TV in Oakland, has accepted a position in...Original post made on Dec. 14, 2009
Last comment by Mark Curtis, on Dec 17, 2009 at 10:23 pm | 14 comments | 1526 Views
AROUND TOWNAlamo evacuated after gas line ruptured
Homes and businesses near the intersection of Danville Boulevard and Stone Valley Road in Alamo were evacuated late Wednesday...Original post made on Jul. 24, 2013
Last comment by Concerned, on Jul 25, 2013 at 1:14 pm | 11 comments | 1526 Views
SCHOOLS & KIDS'Scary Larry' retiring after 20-year reign of 'terror'
Known as "Scary Larry" Valley-wide, Larry Chan has been the supposed terror of the Pleasanton DMV for 20 years. But on Friday,...Original post made on Jul. 27, 2011
Last comment by C. R. Mudgeon, on Aug 1, 2011 at 5:04 pm | 11 comments | 1525 Views
Page 74.75 of 263
Hayward NAACP officials threaten blog posters
By Tim Hunt | 21 comments | 1,639 views
Not so speedy trial
By Roz Rogoff | 4 comments | 1,244 views
By Tom Cushing | 0 comments | 98 views


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My Singing Monsters Answers for iPhone - iPodHome / iPhone - iPod /
Game Questions & Answers (Q&A) service lets you ask questions about video games for game consoles or PC games. So ask your My Singing Monsters question for iPhone - iPod and get answers from real gamers or answer questions and share your insights and experience with the rest of the gaming community.
- Developer: Big Blue Bubble Inc.
- Publisher: Big Blue Bubble Inc.
- Genre: Role-Playing General
- Release Date: Sep 3, 2012
- ESRB: Not Set
Question & Answers
Wishing torches
How do the torches get the fire sign so friends can light them? My friend is trying to light my torches and nothing happens.
Answer from: Sugar
Each friend can only light on torch per friend per day.
Answer from: Luketheminer
Each friend can light one torch for each friend
Answer from: Wow
What they said and if you don't see the little sign that has there islands name on it then get out of the game restart it and get back on I don't know if it will work but it works for me
Unanswered Questions
From: SpottedLeafsGoo
Posted on: 10-31-2014
My Singing Monsters - Gameplay Video
- Jul 1, 2013, Views: 1075
My Singing Monsters - Teaser Trailer
- Jul 1, 2013, Views: 840
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Xbox 360
This page contains Ascend: Hand Of Kul Unlockables for Xbox 360 called "Achievements" and has been posted or updated on Jun 29, 2013 by Packaging. Let us know what you think of this Unlockable by thumbs voting.
- Developer: Signal Studios
- Publisher: Microsoft Game Studios
- Genre: Action General
- Release Date: Sep 25, 2013
- ESRB: Mature
Complete one of the following achievements to collect their Xbox Live Gamerscore points:
|How to Unlock:
|A Fistful of Runes (5 GP)
|Slotted 3 runes
|Ascended (5 GP)
|You made the ultimate sacrifice and Ascended your first Caos
|Battlemage (10 GP)
|Cast 25 Crusade Spells
|Blood Money (10 GP)
|Looted 30 items or purchased 10 spells
|Bone Collector (5 GP)
|Killed 25 enemies
|Caos Chaplain (10 GP)
|You have blessed 20 players
|Caos Supremacy (25 GP)
|Attained 2000 points of armor
|Caos Unleashed (5 GP)
|Created first Caos
|Carving a Path (10 GP)
|Acquired a spell from each alignment
|Cast Out (10 GP)
|Banished 25 enemies into another player's realm
|Champion of the Gods (40 GP)
|Reached level 50 or Ascended 3 times
|Deep Pockets (20 GP)
|Spent 30,000 souls or purchased a Soul Pack
|Dungeon Master (20 GP)
|Reached floor 50 of the Endless Dungeon
|Friend or Foe (5 GP)
|Sent a curse or blessing to another player
|Hex Master (10 GP)
|You have cursed 20 players
|Killing Fields (30 GP)
|Slaughtered 1000 enemies
|Know thy Enemy (5 GP)
|Defeated 3 player bosses
|Lord of War (30 GP)
|Contributed 50,000 points to the Crusade
|Master and Commander (5 GP)
|One of your Ascended Champions defeated another player
|Nuker (10 GP)
|25 enemies know the power of magic from their graves
|Outfitted for War (20 GP)
|Attained 200 points of physical damage
|Power Overwhelming (20 GP)
|Fully upgraded a spell
|Shift of Power (5 GP)
|Raised 3 shrines for your God
|Silence of the Trolls (10 GP)
|Decimated 200 enemies
|Sticks and Stones (10 GP)
|Allied humans killed 50 enemies
|Tastes Like Chicken (5 GP)
|Consumed 20 humans
|Total Control (5 GP)
|Did 20 10x combos!
|Uninvited (5 GP)
|Used an Alignment Mask boost to enter a restricted alignment dungeon
More Unlockables
Back to all Cheats
Stuck on this game? Set a specific, clearly defined question and let others answer your question or view answers to previously asked questions. If you think you are an Ascend: Hand Of Kul expert then please try to help others with their questions.
Latest Questions
How do you start weekly challenge
From: Tallpaul
Glitch? plz help
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Alter of dust bug?
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From: Master deeds
Claim the blood shrine
From: Tophat
Help darkrum quest waypoint is glitched!
From: Klngnlnja
Character freezes?
From: BmanFireFlame
Finding darkum??
From: Clark
Help Killed Kul and no gift
From: Stan0420
Training not working
From: Conman111
Curse other players?All QuestionsAsk a Question
From: What bro?
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Centrum performance tablets
£7.50 (25p each)
Product Summary
HELPS SUSTAIN MENTAL&PHYSICAL ENERGY. Centrum Performance is a complete daily multivitamin with minerals supplement, specially formulated for sportspeople and those leading busy lives! MENTAL&PHYSICAL ENERGY. MULTIVITAMIN WITH MINERALS FOOD SUPPLEMENT FOR ADULTS. A to Zinc + GINSENG&GINKGO BILOBA. Centrum Performance is a complete daily multivitamin with minerals supplement for highly active people to support an energised life style! ENERGY. Helps unlock energy from food needed for your mind and body. STAMINA&ENDURANCE. Ginseng&Iron may help your body sustain energy and stamina needed for physical performance. CONCENTRATION&LEARNING. Iron plays an important role in maintaining healthy blood needed for concentration and work performance. CIRCULATION. Iron, vitamin B12 and vitamin E can help maintain a healthy heart and circulation. For more information, visit www.centrum.co.uk. Centrum Performance is specially formulated for highly active people, like sportsmen and women, to support an energised life style! WORLD'S No 1 MULTIVITAMIN†. To learn how Centrum Performance can help you feel your best, visit www.centrum.co.uk
Usage Instructions
- Directions for use. Take one tablet daily with water, preferably with food. Do not exceed the recommended daily dose. A healthy lifestyle and a varied and balanced diet are important. This product should not be used as a substitute for a varied diet.If taking other supplements, please read the label, since they may contain the same ingredients. Product contains iron, which can be harmful to children if taken in large doses.Suitable for adults over 16. This product is not suitable for pregnant or breast feeding women. The container inside this pack is sealed for your safety. Do not use if the foil is broken.
Store out of sight and reach of young children.Store dry and not above 25°C. Always replace lid after use.
Please note that whilst we take every care to ensure the product information displayed on our website is correct, product recipes are regularly changed and this may affect nutrition and allergen information therefore you should always check product labels and not rely solely on the information presented here.If you require specific advice on any Waitrose branded product, please contact Customer Support on 0800 188884 or email firstname.lastname@example.com. For all other products, please contact the manufacturer.This information is supplied for personal use only. It may not be reproduced in any way whatsoever without the prior consent of Waitrose Limited nor without due acknowledgement.


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How to Wear Fall's Hottest Color Combination
It's black and white, of course! And the best thing about it is that there's none of that attempting-to-match business. These finds will go with (and add polish to) everything you already have in your closet.
By Ava Feuer
Color study
A classic cowl-neck is flattering, not frumpy, thanks to cute-and-flirty polka dots. Optic Dot Cowl Neck 3/4-Sleeve Dress, $69.50; Loft.
Courtesy of the Company


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Arkansas Resolution Against Marriage Equality Fails and House Speaker Reacts
May 16, 2014 by HRC staff
On Friday, Republican Arkansas State Senator Jason Rapert attempted to have the state's legislature pass a resolution in support of Amendment 83 which enshrined marriage discrimination into the state constitution. It failed. The resolution required a six-day notice to be considered, but Rapert wanted to suspend the rules requiring a two-thirds vote. The item did not get the needed votes.
Republican House speaker Davy Carter voted against suspending the rules to consider the resolution. "I believe in our constitution and our system of government. Whether or not our state's constitutional amendment runs afoul of the United States Constitution is a question for our highest court," said Carter. "Judicial intimidation by the legislative branch is not appropriate in this instance or any other."
The resolution comes a week after Pulaski County Circuit Judge Chris Piazza ruled the state's ban on same-sex marriage is unconstitutional. Since then, hundreds of committed couples across the state have received marriage licenses. Rapert's resolution also called Judge Piazza's ruling an abuse of his judicial authority and sought to invalidate the marriages performed after his ruling.
Though the resolution is non-binding, it would have urged the Arkansas Supreme Court to uphold the ban preventing loving gay and lesbian couples to marry in Arkansas.
Earlier this week in Arkansas, Human Rights Campaign President Chad Griffin launched Project One America, an unprecedented effort to dramatically expand gay equality in Arkansas, Mississippi and Alabama. HRC is making a deep and lasting $8.5 million investment concentrated in these three states. An office with dedicated staff will soon open in Little Rock.
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The slight variations that occur from bead to bead on this strand will add an aged look to your designs. Beads measure 2.5mm across.
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For new questions please post at magento.stackexchange.com, the community-run support site for the Magento community. We will be providing updates on the new forum solution soon. For questions or concerns please email email@example.com.
First sorry for my bad english
I like to offer tiered pricing based on a customerâs purchases of products in a certain category over the past 12 months
Basically the regular tiered pricing in Magento, but accumulate all quantities of an item purchased over the past 12 / 24 months and put the customer in a tier based on that. Are there any extensions or has anyone heard of / done anything like this?
if a product have a Tier pride for this Quarter (jenuary to march, example)
A .- 1 to 10 units = 10$ Unit
B.- 11 to 20 units= 9$ Unit
C- 21 to 30 units =8$ unti
You can buy today 3 units,,, the next week 5, the next month 4units; This is Iqual= 3+5+4= 12Units
The fits ten units we want sell to 10$ each, but the other 2units = 9$
When the quarter is end,,, the rule need come to zero again.. , in April we can made the same or different promotion in this product
please, can you help me and tell me if some extension can made this or similar?
Thank you in advanced
In near of two years… any one have a solution or idea about this???
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