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BUSM Faculty Named Top Docs
Boston Magazine has released its annual Top Docs issue. Sixty-two BUSM faculty and...
Lauren Sweetser, a first year student at the BU School of Medicine, was named an Albert Schweitzer Fellow for the 2014-15 class. She will join approximately 220 other 2014-15 Schweitzer Fellows spending the next year learning to effectively address the social factors that impact health, and developing lifelong leadership skills. In doing so, they will follow the example set by famed physician-humanitarian Albert Schweitzer, for whom their Fellowship is named.
Sweetser's focus is addressing issues of pediatric homelessness in Roxbury, Mass. with a service-learning project "Resources and Education for Adolescents and their CHildren" (REACH). The mission of REACH is for medical students to work with and learn from homeless teenaged mothers and their young children by actively supporting them through educational workshops, constructive childcare and longitudinal multifaceted mentorship.Ultimately, the goal is for medical students to serve as healthcare liaisons for this often-neglected population while encouraging positive consistent relationships for both mother and infant.
Upon completion of the Fellowship year, the 2014-15 Boston Schweitzer Fellows will become Schweitzer Fellows for Life and join a vibrant network of nearly 3,000 Schweitzer alumni who are skilled in, and committed to, addressing the health needs of underserved people throughout their careers.
On Saturday, May 17, members of the BUSM Class of 2014 gathered to celebrate their graduation from medical school. Congratulations, Grads! View the pics on Facebook
Graduates Welcomed to Medical and Scientific Community
The 167th Boston University School of Medicine commencement opened with an academic procession of 300 members of the faculty lining up on either side of the Class of 2014 to welcome them into the community of scientists and physicians. The ceremony, held at the Agganis arena on May 17, was a celebration of achievement and commitment to medical research and caring for patients.
"We gather together today to publically recognize and celebrate the credentials that these degree candidates have earned, a major life transition," said Dean Karen Antman, MD. "I speak for the faculty in saying that it has been a great privilege to work with you. You are smart and committed, resilient and adaptive."
The degrees earned by the Class of 2014 included 52 PhDs, 157 MDs, 12 MD-PhDs, 10 MD-MPHs, and six graduates who received an MSc.
"It has been said that 'life is what happens when you are otherwise making plans,'" said U.S. Assistant Secretary of Defense for Health Affairs Jonathan Woodson, MD, who delivered the commencement address. "I have found this to be true time and again, and it expresses the need in life to expect the unexpected. Each of you should be prepared to negotiate around obstacles even as you keep your eye on the prize or the long range goals you have set for yourself. It is important to understand that deviations are the friction points in life when we learn the most about ourselves and we grow.
Woodson asked the parents of the graduates to stand to be recognized for their support and dedication that helped make their children's accomplishments possible.
Speaking for her fellow doctoral students, Ariana Harris, PhD, noted, "To solve the mysteries of the world, we need each and everyone one of us to contribute. In a little while we will received our academic hoods and you will hear the titles of our individual projects, getting a sense of how different they are. This is what makes the scientific community amazing. There is so much to learn and so many of us are eager to figure it out. I am confident that whatever careers we pursue as individuals, our thirst for knowledge will continue. We use our scientific training every day. We search for logic, reason and evidence that support our thoughts and beliefs."
Referring to the white coats he and his classmates received upon entering BUSM, Brian Curry, MD, speaking on behalf of the medical students, said, "We received these as a symbol of our induction to a calling. We didn't realize it at the time, they also symbolized the granting of a very special kind of power. One that, just like our white coats themselves, we have spent the better part of four years clumsily trying to grow into and will likely continue to do for the rest of our careers. My message to you, BUSM class of 2014, is simply this: Earn this power. Earn it, but recognize we will never own it. We only can ever be responsible stewards of this power our patients have entrusted to us. Though today marks the retiring of these short white coats, we should never allow ourselves to get fat and happy with the notion that we have somehow grown into them. We must earn it anew every day, with every patient, always."
Boston University's Schools of Medicine, Public Health, Dental Medicine and the Division of Graduate Medical Sciences are proudly sponsoring the John McCahan Medical Campus Education Day on Thursday, May 22, 8:30 a.m.-3:30 p.m. in the BUSM Instructional Building, Hiebert Lounge 14th Floor.
"Education Day is a fantastic opportunity to meet and network with innovative educators from across the entire medical campus," explains BUSM Gross Anatomy Course Director Ann Zumwalt, PhD, who also serves as chairman of the event planning committee. "The event showcases creative educational initiatives and is consistently inspiring and invigorating for BUMC educators."
The purpose of the event is to showcase and enhance educational innovations, scholarship and research across the Boston University Medical Campus. All faculty, students, residents, fellows and staff of BUMC are invited to attend.
Register online: http://www.bumc.bu.edu/jmedday/ Registration by May 22 is required for workshops and lunch.
Program Highlights
Keynote Lecture: (8:45 a.m.)
The Art and Science of Giving Feedback
Carole Pfeiffer, PhD
University of Connecticut Health Center
Dr. Pfeiffer is a Professor of Medicine and a sociologist who has worked in medical education for three decades. She is the Director of the Clinical Skills Assessment Program at the University of Connecticut School of Medicine and was a founding member of the Association of Standardized Patient Educators. She has a particular interest in communication skills in the clinical encounter.
Poster Session: Posters focus on themes of educational innovations, research and technology. Oral presentations and awards will be given for outstanding student, fellow/resident and faculty abstracts
Luncheon: Pre-registered attendees will be provided lunch. Register
Faculty Workshops: Pre-Registration required. Participants will learn about educational strategies, innovations, research and scholarship by attending the interactive workshops. See workshop details and registration online.
Contact: For more information, contact Liza Young, 638-4799 or firstname.lastname@example.com
John McCahan Medical Campus Education Day
Eliminating financial barriers to a fitness center as well as providing physician support, a pleasant environment and trained fitness staff did not result in widespread membership activation or consistent attendance among low income, multi-ethnic women with chronic disease risk factors or diagnoses according to a new study from Boston University School of Medicine. The findings, published in Journal of Community Health, is believed to be the first study of its kind to examine patient characteristics associated with utilization of community health center- based exercise referral program.
Currently, fewer than half (47.3 percent) of Americans meet expert recommendations of 150 minutes per week of moderate-intensity exercise or 75 minutes per week of vigorous-intensity exercise. Women are less likely than men to meet guidelines for physical activity. Certain subpopulations are at elevated risk for both inactivity and CMD, including Hispanics, African Americans and those below the poverty level.
Adult female patients of a community health center with an affiliated fitness center, were included in the study if they received a referral to the fitness center from their primary care provider. Demographic and medical information was abstracted from their medical chart and fitness records were abstracted to measure activation of a fitness center membership (creation of an account denoting at least an initial visit) and utilization over time.
The researchers found less than half of the women activated their memberships (40 percent), although Black/African Americans women and those with higher numbers of co-morbidities were more likely to activate. In addition, only a small subset–10 percent of women who activated their memberships (0.4 percent of the total referred sample)–achieved three-month participation levels consistent with cardiometabolic disease (CMD, including heart disease, hypertension, hyperlipidemia, Type 2 diabetes) risk reduction. Nonetheless, average visits per month declined from the beginning to the end of the free 3-month trial membership period.
"Despite providing free access to a fitness center and its staff, the number of women utilizing this service was highly variable," explained corresponding author John Wiecha, MD, associate professor of family medicine at BUSM. "Our observations are consistent with findings from the United Kingdom, where a recent systematic review found that exercise referral "uptake" (attendance at an initial consultation) by participants varied from 28 to 100 percent and "adherence" (signifying participation in at least 75 percent of all sessions) from 12 to 93 percent," he added.
According to Wiecha, these findings suggest that program design may benefit from developing activation, initial participation, and retention strategies that address population-specific barriers and integrate credible behavioral change strategies. "Significant public health gains could be realized by increasing physical activity among populations at high risk of chronic disease, and additional research is warranted to develop effective models in the U.S.," said Wiecha.
The BUSM Historical Society is proud to announce publication of Volume II of Aceso: Journal of the Boston University School of Medicine Historical Society.
The BUSM Historical Society mission is to expose students and the BUSM community to the rich history of the School, Boston Medical Center, medicine in Boston, and the medical profession in general. By exploring how the landscape has changed and the profession has evolved, and introducing people and innovations that helped create modern medicine, the society offers perspective and inspiration for students to carry throughout their careers.
Aceso: Journal of Boston University School of Medicine Historical Society is named for the Greek goddess Aceso and comes from the Greek word akéomai meaning "to heal." Aceso represented the healing process. Unlike other gods, she personified medicine from the patient's perspective as a process involving both the ill person and the physician. Aceso was involved in overall care and the recognition that healthcare and well-being took time and was an active process.
"This aspect of healing is in striking accord with the BUSM mission and BU CARES educational philosophy," says Michael Sherman, BUSM '15, Aceso founder and editor-in- chief. "In our journal we hope to highlight medical history and all of its manifestations. With Aceso, it is our intent to awaken the reader to the common ground we all share. By exposing readers to the vast experience that the humanities offer, we will provide a better understanding of our place in medicine and society."
"Trauma Informed Services: Implications for Healthcare Providers and Systems"
Carole Warshaw, MD
Director, National Center on Domestic Violence, Trauma and Mental Health
Executive Director, Domestic Violence Mental Health Policy Initiative
Tuesday, May 13
Noon-1 p.m.
BUSM Instructional Building, L-110
This annual memorial lecture is in honor of Lynne Stevens, LICSW, BCD (1946-2009), the director of the Responding to Violence Against Women Program and an Assistant Professor in the Department of Family Medicine. She was a clinician, activist and researcher who worked locally, nationally, and internationally, specializing in evaluation of the quality of care offered to women who were victims of violence.
Attendees are cordially invited for lunch at 11:45 a.m. and a Q & A discussion from 1-2 p.m. with Dr. Warshaw following the lecture.
The Boston University community includes 300,000 alumni and 29,000 parents around the globe, along with 30,000 students and 9,000 faculty and staff members. On Wednesday, April 30, the University will ask that far-flung group to come together for 24 hours—on campus and online—for the first-ever Giving Day.
The 24-hour fundraising drive will benefit the BU Annual Fund, which provides resources for the University's schools, colleges, and athletic teams, as well as for scholarships and other initiatives. BU community members are encouraged to donate, participate in on-campus activities, and spread the word through social media. Donors can give to their choice of program or area within BU. But time is limited: Giving Day starts at 12:01 a.m. EDT on April 30, and ends at midnight EDT.
"This is an opportunity for alumni, students, parents, and friends to make a huge difference in a short period of time, uniting around a common goal," says Dan Allenby, assistant vice president for Annual Giving. "Giving Day is all about participation; giving back to what made, or makes, your BU experience so great, supporting future students, and building community."
To increase the impact of Giving Day, and to encourage and reward the philanthropy of other participants, BU trustee Stephen Karp (CAS'63) has issued a challenge: He will match, dollar for dollar, any gift of less than $1,000, and the first $1,000 of each larger gift.
To take advantage of the matching challenge, the Class Gift Committee is encouraging seniors to give to the Class Gift Campaign on Giving Day. "This is a great opportunity for students to take action and demonstrate why they love BU," says Markiesha Ollison (CGS'12, SMG'14), the committee's marketing chair. "I'm excited to interact with alumni. To students, alumni seem like distant cousins. But on a day like this, they seem more like brothers and sisters."
Alumni, parents, and friends around the world are invited to get involved through social media. "It's a time for alumni to reflect on the meaningful connection they have with the BU community," says Mark DiCristofaro (CGS'06, COM'08), a film and TV producer based in Los Angeles. "For me, those connections have become clearer down the line."
DiCristofaro plans to donate on Giving Day, in honor of those connections, and to say thank you to those whose contributions enriched his student experience. "At the College of General Studies and the College of Communication, enhanced facilities and equipment were donated by parents and alumni, and those had a direct effect on my BU experience," he says. "And as a member of the golf team, I benefited from contributions from team alumni, which offset the cost of our travel and gear."
On-campus activities
Local alums can be a part of Giving Day across the Charles River Campus. At stations set up in the School of Management lobby, on Marsh Plaza, at the GSU Link, and at FitRec, student volunteers and BU staff members will answer questions, take donations, give away prizes, stage contests, and take photos and shoot videos to share online, so that alumni, parents, and others who aren't on campus can be part of the fun for the day. And don't forget to visit the photo booth on Marsh Plaza.
Social media activity
Participants can use the hashtag #BUGivingDay on Facebook, Instagram, Twitter, and Vine posts to be part of the conversation—and to check out what others are saying about Giving Day. To show your support, switch your cover and profile photos to the Giving Day–branded versions available on the Giving Day website. After you donate, tell the community why, by posting your own video, photo, or testimonial using the #WhyIGivetoBU hashtag. Throughout the day, the BU Alumni Association will share #WhyIGivetoBU posts, and send out updates and bonus challenges, including opportunities to earn extra funds for individual schools and colleges.
Giving Day starts at 12:01 a.m. EDT on April 30, and ends at midnight EDT. Donate on April 30 here. Questions about Giving Day? Email firstname.lastname@example.com, call 800-447-2849, or visit the website. Learn more about all of the great reasons to give to BU here.
This Bostonia story was written by Alyce Nicolo (COM'07)
Gerard Doherty, MD, chair of the Department of Surgery at Boston University School of Medicine (BUSM) and chief of Surgery at Boston Medical Center (BMC) and has been elected as President of the American Association of Endocrine Surgeon (AAES). He will serve as President through 2015.
As president, Doherty will preside at council assemblies and the annual members' assembly. He will appoint members to all committees, serve as an ex-officio member of each, appoint successors to open positions, and deliver the 2015 Presidential Address.
Endocrine surgery is the discipline of surgical management of endocrine disorders, including the understanding of the disease process, and comprehensive care of surgical endocrine disease of the neck and abdomen. The AAES is dedicated to the science and art of endocrine surgery, and maintenance of the highest standards in clinical practice.
"Being chosen by my colleagues to fulfill this role is a distinct honor. The AAES has been my professional home throughout my career, and I admire the many achievements that we have made as a group to improve the care of patients, to advance the field, and to train the next generation of practitioners."
Doherty's clinical focus is endocrine oncology and comprises surgical diseases of the thyroid, parathyroid, endocrine pancreas and adrenal glands, as well as the surgical management of multiple endocrine neoplasia (MEN) syndromes.
Prior to coming to BUSM and BMC in 2012, Doherty spent a decade as chief of General Surgery at the University of Michigan Health System. He is the immediate past-president of the Michigan Chapter of the American College of Surgeons and has held multiple leadership positions in national and international professional groups, including the Board of Directors of the American Thyroid Association.
A graduate of Holy Cross and Yale School of Medicine, Doherty completed his residency at the UC-San Francisco, including Medical Staff Fellowship at the National Cancer Institute. He joined the faculty at Washington University School of Medicine in 1993 and became professor of Surgery there in 2001.
In the video above, CReM founders Darrell Kotton, Gustavo Mostoslavsky, and George Murphy discuss how they use iPS cells to study disease development, conduct drug screenings, and eventually to correct genetic mutations, with the goal of producing healthy tissues and organs for transplantation. Photo by Jackie Ricciardi
"Our mission is to decrease the burden of human suffering on the planet, help patients, and advance new knowledge." —Darrell Kotton
With the motto Advancing Science to Heal the World the BU stem cell scientists who founded the Center for Regenerative Medicine (CReM) could be pegged as starry-eyed idealists or scientific superheroes. Or perhaps a bit of both.
CReM codirectors Darrell Kotton, Gustavo Mostoslavsky, and George Murphy have established themselves as venturesome researchers who are willing to share their discoveries with almost anyone. And they do it for free—bucking the prevailing trend to patent, publish, and protect scientific breakthroughs. The trio's "open source biology" is just one of the things they teach to the next generation of stem cell researchers at CReM.
Open source biology can seem antithetical to scientists in an extremely competitive field. One young researcher training at CReM recently approached Kotton, a School of Medicine professor of medicine, seeking advice on how to answer an outside request for a vial of stem cells that took several years and hundreds of thousands of dollars in federal grants to develop. The obvious answer, the trainee assumed, was to tell the researcher to wait until the discovery was published.
Kotton saw it differently. "Our mission is to decrease the burden of human suffering on the planet, help patients, and advance new knowledge," Kotton reminded him. "If this competitor of ours has the same goal, then we're obligated to share this cell vial with them, because that's going to achieve our mission.…which is not to get credit and to stroke our egos."
A naïve response? "Here's the thing that nobody talks about," says Kotton. "If you behave in this way, people in our community quickly get the idea that the BU-BMC CReM are the good guys of science. At some point, the equation gets so lopsided that people almost feel embarrassed that they're not sharing with you and so they tell you stuff, and the whole field starts to move forward."
In fact, CReM founders say that increasing numbers of researchers are asking CReM to collaborate on grants, and foundations have begun to recognize that funding a CReM project very probably means that resulting knowledge, expertise, and reagents will be shared with other academic or nonprofit laboratories without restriction or exclusivity.
"I can't emphasize enough how unique that was for the community," says Mostoslavsky, a MED assistant professor of gastroenterology. "We have dozens of emails that testify to that, saying, 'I must tell you this is the first time in my 30 years of being a scientist that someone replied and sent me stuff the same week of asking for it.'"
Still, Mostoslavsky says, there is a "fine balance that is not easy to achieve" between freely sharing their work and protecting it once research has advanced to the clinical stage. "That is a major undertaking," he says. "It's very expensive—no academic institution can support it—so we do need a company to move forward," which also means they'll need patented protection of intellectual property.
Scientific soul mates
Kotton, Mostoslavsky, and Murphy met as Harvard postdoctoral fellows in the lab of renowned stem cell scientist Richard Mulligan, who is famous for his rigorous research and forthright style of mentorship. "It was more of a sink-or-swim methodology, where you really had to prove yourself," says Murphy, a MED assistant professor of medicine. "Coming out of there, we were battle-tested and bombproof."
The three gravitated toward each other as "scientific soul mates," Mostoslavsky says. Long after fellow researchers had left the lab, they would gather for late-night pizza and animated discussions, probing one another's data to test the strength of their work. "We were each other's worst critics as well as biggest fans," Kotton says. It was around that time that they began toying with the idea of conducting science their way—in a meticulous, yet open and collegial manner.
After completing his Harvard fellowship, in 2006 Kotton returned to MED, where he had done a fellowship previously, to launch his own lung stem cell lab. He confesses to "putting psychological pressure" on his friends to follow him to BU, and he is not at all unhappy that it worked. In 2008, Mostoslavsky came aboard, creating his own lab. He was followed soon after by Murphy.
Several events conspired to launch CReM on the Medical Campus. The founders discovered a strong advocate in David Coleman, Wade Professor and chair of the MED department of medicine, who emphasized the importance of a robust research presence on the Medical Campus. Kotton, Mostoslavsky, and Murphy had followed closely the rapid advance of stem cell biology since 2006, when scientists at the University of Kyoto developed induced pluripotent stem cells (iPS) by reprogramming an adult differentiated cell. A tinkerer at heart, Mostoslavsky was fascinated by the Kyoto process, but felt he could go one better. In 2008, he developed a more efficient tool to generate stem cells, called the stem cell cassette (STEMCCA). BU patented the tool, which has become industry standard.
In 2010, with STEMCCA and multiple publications under their belts, the trio established a virtual Center for Regenerative Medicine, with its own website, seminar series, and iPS cell bank carrying branded labels. All this was accomplished while working in separate labs, with Murphy's and Mostoslavsky's divided by floors within a building, and Kotton's located across the street.
As the number of stem cell biologists, physician-researchers, and biomedical engineers grew on both BU campuses, the affectionately labeled CReM brothers felt it was time to pitch a physical center to BU President Robert A. Brown, who firmly backed the idea. Boston University and Boston Medical Center invested jointly in the endeavor, and in November 2013, CReM opened in its newly remodeled space on the second floor of 670 Albany Street.
In the video above, CReM founders discuss how they use induced pluripotent stem (iPS) cells in their labs.
Clinical trial in a test tube
CReM's mission is to advance stem cell research and regenerative medicine for the treatment patients, in particular those at BMC, with diseases such as cystic fibrosis, emphysema, sickle cell anemia, and amyloidosis. Investigators collect blood or skin cell samples, usually from patients at the Alpha-1 Center, the Center of Excellence in Sickle Cell Disease, and the Amyloid Center, and reprogram them into iPS cells.
"Any cell can be reprogrammed," says Mostoslavsky. "It's a true biological rejuvenation. The cells really go back in time." Researchers now have the ability to coax iPS cells—which uniformly carry a patient's genetic mutations—into their desired cell line, such as lung, liver, or blood. (CReM's iPS cell bank stores at least 13 such cell lineages.) Mostoslavsky says the resulting cells are "still a work in progress," compared to those found in nature, but the process allows researchers to watch how an iPS-derived lung cell develops the early stages of cystic fibrosis. What took years to unfold in a patient takes days in the lab.
CReM investigators can screen drugs against patient cell lines to determine which medications are most effective for a specific genetic mutation—the "clinical trial in a test tube," as Murphy calls it. "In theory," he says, "you could develop therapies that are molded specifically for a particular patient with a particular disease."
Developmental biology and drug screenings are now CReM's bread and butter, but its founders keep in mind what they call their long-term "Apollo projects," such as genetically engineering iPS cells to correct patients' mutations. The resulting healthy cells could be cultured and multiplied to regenerate a transplantable organ that wouldn't be rejected by the patient's body. That particular medical breakthrough would mean Kotton's wife would need to look for a new job. Camille Kotton is a transplant infectious disease physician at Massachusetts General Hospital, and Kotton jokes that his "goal is to put her out of business."
Kotton has been collaborating with a team of MGH researchers using a technology called lung decellularization and recellularization, which strips the organ of its cells and repopulates it with genetically engineered copies that lack the patient's original mutation. Theoretically, the reprogrammed cells could multiply, fill the lung's scaffolding, and someday be used for transplantation.
Kotton, who thinks it will be possible eventually to re-create lungs via 3-D printing technology, is collaborating on this with Christopher Chen, a College of Engineering professor of biomedical engineering.
Meanwhile, Murphy dreams of brewing blood. "The human body makes 2.5 million red blood cells every second of every day," he says. "How does one contend with that from a research platform?" He thinks they will be able to "harness molecular cues" that exponentially increase the amount of artificial blood they can produce in vitro. Such a discovery could eliminate the need for blood donation in the United States and—even more urgent—in Third World countries, where the practice is not widely accepted.
Another of Murphy's Apollo projects is boutique blood, or the development of small batches that could be produced for people who suffer from sickle cell anemia or the blood disorder beta thalassemia and require transfusions of rare blood types.
Researcher as healer
In the past four years, word has spread about the CReM founders' work to the point that as well as the emails from potential collaborators who want access to their work, they now get email from patients who either suffer from the particular disorders they study or have children who do.
The latter are heartrending. "'We will sign whatever you want us to sign, and we don't care how experimental your platform is, we would still like to use it to save our kid,'" Murphy recalls reading. He explains that although his team is working hard to find new treatments, right now there are no current stem cell therapies for their child's condition. Asked when they might be available, he replies, "'Sooner than you think.' That's vague, but it's hopeful. And it also is the way that we see things."
Kotton likes to tell a story that underscores CReM's potential. He and his colleagues were approached about a child who suffered from severe cardiac arrhythmias. Their labs developed iPS cells from the boy's skin cells and differentiated them into heart muscle cells, then sent them to researchers in New York City, who screened them against a series of drug regimens until they found a winning combination. After three months on the medication, the boy's arrhythmia decreased from 100 incidents per month to zero.
"This success story represents, I believe, the first human being on planet Earth to be helped by the new iPS cell technology," Kotton says. "If there is one patient who can benefit from these cells, then surely there are myriad more for generations to come."
This BU Today story was written by Leslie Friday. Videos by Joe Chan
BUSM researchers have discovered that the anti-seizure drug ezogabine, reduced alcohol consumption in an experimental model. The findings, reported in the American Journal of Drug and Alcohol Abuse, may lead to more effective treatments for alcoholism.
Excessive consumption of alcohol is one of the leading causes of illness and death in the U.S. and has significant negative economic impact by limiting the productivity of workers and necessitating huge health care expenditures.
According to the researchers, this study provides the first evidence that alcoholism can be treated by this newly discovered mechanism that helps to regulate brain activity known as Kv7 channel modulation. "This finding is of importance because ezogabine acts by opening a particular type of potassium channel in the brain, called the Kv7 channel, which regulates activity in areas of the brain that are believed to regulate the rewarding effects of alcohol," explained lead author Clifford Knapp, PhD, associate professor of psychiatry at BUSM. "This research indicates that drugs that open Kv7 channels might be of value in the treatment of alcoholism," he added.
Previous studies conducted by this research group helped to establish the value of anti-seizure drugs as medications to treat alcoholism. However, further research needs to be conducted to establish that the effects of this drug result primarily from its actions on Kv7 channels. "Because of the close proximity of the doses at which ezogabine reduces drinking and those at which it is reported to produce motor impairment, it is still important to continue to investigate how selective the actions of ezogabine are on the neuronal mechanisms that control alcohol consumption," said Knapp.
The researchers believe these finding will encourage the search for other drugs that act on this system to discover more effective treatments for alcoholism.
This work was supported by the NIH Grant R01AA015923 (to senior author Domenic A. Ciraulo, MD) and by funds received from the Gennaro Acampora Charitable Trust Fund.


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Flora Bernard
Flora Bernard is a Salt Lake City climate activist. She is a recent alumnus of the University of Utah, with a B.A. in political science. She is proud to be on the advisory board of Peaceful Uprising, a Utah-based climate action group, and volunteers with other local environmental and social justice organizations. Flora is a musician, fictionist and spoken word artist, and volunteers for KRCL, Salt Lake's progressive community radio station. She intends to pursue her graduate studies in literary non-fiction and environmental journalism. In her spare time, Flora is an insatiable reader, a music enthusiast and a loyal fan of public radio.
|"...The reality is it is my son's body to do with as he chooses! ..."
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subset: commoncrawl


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Resources and Publications
Resource and Publication
Defense innovation is a key driver of U.S. security and economic competitiveness, however our preeminence in...
The EU's HTTP Cookie Notification Policy is costing Europe $2.3 billion a year and needs to go.
A ranking of 125 nations on the level of government imposed taxes and tariffs on ICT goods and services.
We are on the cusp of an IT-enabled transformation of transportation.
This report ranks 55 nations on the extent of how they practice trade mercantilism.
This report assesses the development of a "data divide" in America.
Policy should be reformed to better integrate the national labs with regional economies.
ITIF presents a framework for evaluating and resolving cross-border Internet policy conflicts.
This report provides a snapshot of states' efforts to create open data policies and portals.
The U.S. Export-Import Bank remains vital to supporting America's traded sector competitiveness.
Using any form of Title II to implement net neutrality would hamper innovation and investment.
New research confirms robots aren't stealing jobs in developing countries either.
Comparisons to electricity and cable TV are off base.
The negative effects of data privacy could outweigh benefits.
We need a middle ground approach to international Internet policy.
The U.S. Department of Agriculture cleared the path to commercialization for a "genetically modified" potato developed by J.R. Simplott.
The President's efforts to promote transparency and good governance should be continued.
To be successful the TPP must protect IP.
New agreement will bring 200 additional ICT products under ITA coverage.
Setting carbon targets will not lead to deep decarbonization.
Stephen Ezell presented at the Entrepreneurship and Innovation in Silicon Valley: Best Practices and...
Daniel Castro will speak about Internet governance in the global economy at an event sponsored by the U.S.-...
Doug Brake participated in the MMTC's Telecom Act Rewrite and the Potential Benefits to MWBEs and...
Daniel Castro will speak about the NSA's impact on the economy, information security, and Internet freedom at...
Stephen Ezell presented on advanced manufacturing at a NIST VCAT meeting.
How Canada's Policies Impact American Innovation and Competitiveness
This panel discussion investigated methods for speeding the path from research to market.
Matthew Stepp gave a speech at the 2013 Regional Meeting of the Federal Laboratory Consortium in Leesburg, VA.
Daniel Castro will speak at a webinar for the Association of Public Data Users on "Public Policy...
Stephen Ezell participated in a panel on Electronic Commerce and Data Privacy at the Frontiers of Economic...
ITIF testifies in Vermont against legislation sought by organic advocates to grow their market by misleading...
ITIF opposes misguided efforts to ban an enviroinmentally superior new biotech variety of grass.
ITIF testimony before the MD Legislature shows legislation to mandate labels for genetically improved foods...
Mandatory GMO Labeling legislation proposed in MD would undermine the objectives it seeks to advance.
Stephen Ezell testifies that India's innovation mercantilist policies damage India's, America'...
ITIF urged an update to the Communications Act that will sustain the amazing innovation in our networks and...
The FTC should embrace a flexible and modern regulatory regime that fosters data-driven innovation in the...
Rob Atkinson files comments to new FCC chair on future of telecom policy.
ITIF recommends that policymakers preserve statutory damages for large-scale infringement, allow the private...
The U.S. freight transportation system faces major challenges and new policies are required to enhance...
Conventional economics provides an increasingly poor guide for economic policy and should be replaced by an evolutionary economics framework.
Rob Atkinson contributed the chapter "Public Policy, Innovation and New Technologies" to the textbook "Guide to U.S. Economic Policy."
Robert Atkinson contributed the chapter "Innovation in Cities and Innovation by Cities" for the book "Creating Competitiveness: Entrepreneurship and Innovation Polices for Growth."
In a chapter for the new book Practicing Sustainability, Rob Atkinson wrote about sustainability from an innovation economics perspective.
"Innovation Economics: The Race for Global Advantage." This new book delivers a critical wake-up call: a fierce global race for innovation advantage is under way and the United States is running the risk of losing.
Daniel Castro contributed a chapter titled "U.S. Federal Cybersecurity Policy" in the book "Cybersecurity: Public Sector Threats and Responses."
Rob Atkinson contributed a chapter titled chapter "Who's Who in Internet Politics" for the book "The Next Digital Decade: Essays on the Future of the Internet."


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Originally written on Everything Colts | Last updated 11/18/14
The Indianapolis Colts have traded rush outside linebacker Jerry Hughes to the Buffalo Bills for inside linebacker Kelvin Sheppard. The Jerry Hughes era is done in Indianapolis. The disapointing first round pick has been shipped off to Buffalo and in return the Colts get a solid inside linebacker in Kelvin Sheppard. Hughes never fully developed with the Colts and never was able to see the field for an extensive amount of time. Hughes finished his Colts career with 62 tackles and 5 sacks. Many fans will be happy to see the 4 year veteran go away. I'm personally disapointed, because the guy had 12 sack a year potential, but he just never fully developed. Let's see how he does in Buffalo.The Colts received Kelvin Sheppard, an inside linebacker for the Bills. Sheppard started almost every game last season and compiled 80 tackles with 2 sacks. He's going into his 3rd season in the NFL. Sheppard arrives at a position where it's quite crowded with guys like Pat Angerer, Jer...
Original Story: http://www.everything-colts.com/apps/...
PLAYERS: Jerry Hughes, Kelvin Sheppard, Pat Angerer, Jerrell Freeman, Kavell Conner
TEAMS: Indianapolis Colts, Buffalo Bills
TEAMS: Indianapolis Colts, Buffalo Bills
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Which Red Carpet Shoe Style Would You Wear? Vote and Be Entered to Win a Pair of Louboutins!
by Sponsor 100 Reactions 155 Shares Print
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macaronibirds 3 years
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I voted for the peep toes. :)
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I'm happy to see stilettos are being so popular again.
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All these businesses & brands have booked, have you?
We have already taken bookings from some of the UK's biggest business and brands including Virgin Atlantic, Hiscox, Global Radio, NEC, TK Maxx, Tesco, Action Aid, AEG, Sports England, Warwick University, House of Fraser, IBM, The Prince's Trust, BBC, The Financial Times, Bloomberg, The Guardian, Volvo, Nationwide Building Society, KLM. Media and ATL agencies including OMD (EMEA & Manning Gottlieb), FUSE, Havas, M&C Saatchi, SMG, iProspect. Not to mention many of our CMA member agencies plus lots of content agencies from across Europe and as far as Dubai! Read more »
The CMA celebrates record number of new members
The Content Marketing Association (CMA), the industry body for the content marketing industry, has announced a record number of members joining the association this month. This follows the move to broaden its membership policy – opening up to media agencies in late 2013, media owners in June 2014 and brands in September 2014. Read more »
Bladonmore pays tribute to The Artist providing tips on creating corporate films
Following the success of The Artist at this year's Oscars, Bladonmore have created a short silent movie which not only offers the top tips of producing a corporate film but also reminds us of how powerful silent communication can be. Read more »
Just one place left on the course!
Due to a last minute cancellation we have just one place left on the course. APA training courses have been created specifically for APA members, and are all directly relevant to the industry and job role needs. Read more »
Important APA Content Marketing research study
The APA is undertaking some new research with the full support of all our members to determine how we as an industry should be positioning ourselves in the future. Read more »1Comments


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I Want to Go Skinny Dipping
Personal Stories, Advice, and Support 1,600 People
Feels So Goodswimming nude is the only way i swim somtimes i get hard when i swim fast sometimes i wonder how the girls would react if i steped out at that time. one good thing about swimming nude is that your shorts dont slow you down if...
thumper197022 36-40, M 1 Response 2 Jan 2, 2010
I've only been once but I'd like to do it again.Last time it was with 5 guys and 3 girls. We were all friends so everyone was pretty comfortable. It was a lot of fun and very exciting (:
SophieSweetie 18-21, F 3 Responses 5 Jul 14
Gray Whale Beach, CAI do, I really do. It is a beautiful beach, CA is more liberal, maybe i can meet up with ppl and we can have a great day at the beach while I am in town.
JackFlirts 51-55, M 0 May 22, 2013
Not at the pool in my back yard,or at the private beach my friend has, but in a public pool. █I'd love it :)
LittleStain 18-21, F 3 Responses 4 Oct 10
The Phrase "skinny Dipping" Is And Can Only Be Used By PervertsBut dont worry it isnt like am an expert on this or doing a Phd on it...oh wait, I am If you have ever used that phrase - you are admitting something - at least to experts on human nature - you are admitting that you dont consider this normal by the very fact that you have a...
RichiNat 26-30, M 4 Responses 0 Jun 7, 2012
After You......One of these days I will build up enough courage to run in after you. Model: Graham Farquhar "The Naked Poet"
Mahal1023 46-50, F 8 Responses 7 May 10, 2012
Skinnny- Innny DippingThat would be funn! It would be like taking a bath minus all the soaping and washing. :D I have very conservative friends, so I know that most of them wouldn't want to go with me. Anyone wanna come with???
stripesANDsunshine 18-21, F 11 Responses 3 Jul 12, 2008
It'd Be Fun...to do it for the first time. You're a bit buzzed with great friends in the cover of night with a moon being the only light that you have....and you ***** to jump into the water. Sounds like fun.
VainGoddess 22-25, F 3 Responses 2 Jul 4, 2013
I Wanna Do It!I'm actually surprised I never went skinny dipping when I was younger as much as I was in the water. Just never happened. Now I think it would be a great memory to have with someone special. I'm willing and waiting someone special! :)
soulrunher 41-45, F 14 Responses 6 Nov 14, 2012
Sneaking Off At The BeachI remember as a young kid really wanting to be naked outside and really wanting to go swimming nude. So, one day we went on a family beach trip, and I wandered off alone as I have been known to do. I soon discovered a trail through the woods, and headed down. After a bit of...
ppprowee 22-25, M 4 Responses 3 Mar 8, 2012
Anybody know of someone in the Kansas City,MO area that would have a private pool to go skinny dipping in?
J1D8L 22-25, M 1 Aug 23
IDKhow2deal 26-30, F 5 Responses 2 Jan 25
What'S The Big Deal Over Skinny Dipping?I don't understand all the fuss about Skinny Dipping. Yes it's unusual to go about naked in public but most of us who do skinny dip do so with friends or family and people we are comfortable being seen naked by. I do so quite often either when at a friend's, in the sea or...
amandaromero2013 22-25, F 26 Responses 24 May 17, 2013
Its actually pretty ridiculousthat I haven't gone skinny dipping yet, anyone care to join me? 😏
catchphrasejones 18-21, M 2 Apr 4
Sneaking Into Neighbors PoolWhen I was younger, for two summers in a row, I would sneak into my neighbors backyard and go skinny dipping in their pool when they weren't home.
SarahLangley 18-21, F 3 Responses 3 Jul 28, 2012
Never Brave EnoughI would love to go skinny dipping it would be so fun but I always get to nervous right before and chicken out haha
Kellysun 18-21, F 31 Responses 10 Jul 5, 2011
Hi, I'm a straight 25 year old guywho lives near KC, MO. I'm a closet nudist because all the rest of my family doesn't condone nudism. I've heard from a lot of people on here how exhilarating skinny dipping and just being nude outside in nature. I go nude in my grandma's backyard because it's really private and...
J1D8L 22-25, M 1 Response 2 Aug 22
I would LOVE to do this.It seems so fun and liberating. The water up against your bare skin in the dead of night with just the light of the moon. My only issue with this is that the bodies of water where I live look EXTRA filthy. I would hate it if I got that disease ridden water into any parts of my...
CharlieAff 18-21, F 23 Responses 15 Jul 14
More Like Chunky DunkinWhen I was growing up in northern Minnesota, we use to go skinny dipping all the time. We lived on the iron range, and there was a flooded old mine close to where I lived. Back then it was fenced off, and we weren't supposed to go in there, but of course we always did...
darknight 46-50, M 13 Responses 5 Jun 24, 2008
OddlyScintilating 46-50, M 2 Responses 3 Jul 14
Dared To GoWhen you are young, you have the will to do just about anything. It was the summer of my last year of high school. I, like so many other young adults, did on occasions, drink underage. Well, this night with a group of friends went down to the lake. It was hot and frankly, we were...
enchantedebonybutterfly 31-35, F 6 Responses 4 Aug 20, 2013
It's Sooooo Easy.....Turn the back porch lights off...open the door and slip outside. 6 steps and you are there. Your choice...jump in or ease down the ladder. I'm right behind you.....
awhitedot 36-40, M 4 Responses 4 Aug 17, 2013
I'm Literally A Disc JockeyDavid Guetta feat Sia's Titanium, Drake's Free Spirit feat Rick Ross, The Spins and Traffic In The Sky by Mac Miller, Tom Ford by Jay-Z, Big *ean's Guap, Lil Wayne's Love Me, Night Out by Martin Solveig, Works For Me by The Twelves, Atmosphere's Shoulda Known, Beastie Boys's...
LonelyBeing 18-21, F 1 Response 0 Nov 12, 2013
I think it's one of those things in life youneed to do once so sure I'd love to do it
SalinNY 46-50, F 6 Responses 9 Apr 14
Skinny-dippingWhen we were about twelve, one of my best girlfriends (there were three of us at the time) suggested we go swimming. It was a hot, humid day, but we didn't have our bathing suits with us. Since we were alone, and the water did look pretty inviting, she said we should just swim...
MarksMom 31-35, F 8 Responses 11 Feb 19, 2010
Evening SwimA few days past we took the dogs to a beach near us to cool them down. It was late afternoon and there where only a few people swimming. It's a state park and a public beach, so no dogs are allowed in the swimming area. But, my wife and I, went down to the far end...
darknight 46-50, M 12 Responses 7 Aug 1, 2008
That's something on my summer bucket list .Who has done it
laredd 18-21, F 3 Responses 6 Mar 9
It's a ballsy move ,but I hope to do it sometime preferably under the cover of the night.. So probably down a ways south. I can only imagine how liberating and the rush one might feel ! Yes I'm doing this sometime !!
MSCris 18-21, F 6 Responses 11 Aug 1
Skinny-dipping Is Great Fun!In 2004, shortly after having a rather unique spiritual experience with God, my wife asked me what I wanted for my birthday. We usually do something special for our birthdays, so 2004 shouldn't be any different, right? Anyway, I had had a "talking-to" from God about my body image...
goofyirishman 56-60, M 1 Response 2 Jun 15, 2012
I Always Wanted To Try ThisIm sure when i find the right friends/girlfriend i would like to try this out at least once.
007nowonline 22-25, M 0 May 10, 2013
Skinny dipping is the only way to swim!Who needs clammy clothes anyway? *****, swim, get out, dry off and get dressed again. Simple enough? Some of us prefer to stay clothes free anyway.
CrazyWaterSpring 51-55, M 1 Response 3 Dec 31, 2013
Lake Nightme and a old girl friend used to have lake night on wedsendays. we would drive out to this one area that had a old boat dock we would ***** and hang our feet off the dock drinking and talking. course we we jump into the lake and enjoy the feeling of it being so...
pr0pwash9 41-45, M 1 Response 2 Jan 23, 2010
Actually Thinking About Doing It Right Now...The sky is beautifully clear. The stars are performing their effortless task of amazing me. I'm in the mood to shed my clothes and jump in the lake. It's how water should be experienced - without barriers. I love to feel it rushing around me...enveloping me as I enjoy its...
PeachesGalore 46-50, F 1 Response 3 Aug 6, 2012
Haha I want to and have!Actually it feels really good. I suggest everyone try it even if it's alone.
zziimm 22-25 1 Dec 2, 2013
It's so cold here, the hot shower I took thismorning felt absolutely amazing. The only thing that would be better would be to jump in a hot tub naked for a little while
J1D8L 22-25, M 2 Nov 13
So my best friend wants to try skinny dippingwith me this summer. We live in Orange county and its gonna be a hot summer for sure since its about 100 degrees today. We also live by the beach. She keeps begging me to try it with her at night. Jut us alone but I'm 50/50. I don't know, the idea of being naked in public sounds...
jeffboy91 22-25, M 4 Responses 3 May 16
FireFly Negril JamaicaI have been to the FireFly in Jamaica three times. Each time has been very enjoyable. The small resort is right on the most beautiful beach call 7 mile beach. You can eat at the local resturants on the beach or stroll on down to Jimmy Buffett's Margaritaville...
deleted 26-30 2 Aug 10, 2009
When I Was YoungI used to skinny dip in our pool when every one went to sleep. The moon would be so bright you could see very clear. The feeling of the cool water on my warm body was like silk brushing against my shimmering skin.
kc4444 51-55, M 3 Responses 2 Jun 29, 2012
Related Experiences
It was on Friday evening, my first ever date! All week he'd been saying well go skinny dipping and I just laughed at it thinking he was joking, but come the Friday and the date...
Vik91 22-25, F 5 Responses 5 4 days ago
Last vacation I went to Punta Cana. Fabulous place! The ocean was so calm. I think we skinny dipped in the ocean 3 nights out of the 7 we were there! Not to mention skinny dipping...
Cilly32 31-35, F 4 Responses 6 Nov 18
My best friends have always been girls, which is the best way to start relationships. My best friend asked me to go skinny dipping with her on her birthday, which became a...
pacman2112 36-40, M 2 Responses 2 Oct 30
Recently I was out of town for work and went skinny dipping in the hotel pool. I've done this a lot over the years so I'm always looking at the hotel pool when I book a room...
kevm4321 46-50, M 1 Response 2 5 days ago
There's a secret pond not far from here where young people like to skinny dip. It's all about having fun and feeling free, and to maximize this fun it's best to have an equal...
deleted 26-30 10 Responses 18 Oct 30
So I graduated and then next was too move away to the big city and start school again two weeks after high school grad. My friends and u decided to go camping and have a big party...
Cilly32 31-35, F 1 Response 5 Nov 18
My whole family does. Now don't get nasty It's not like that We just don't see any sense in wetting bathing suits to go into our own pool where no one else can see us anyway
Tasha15Girl 13-15, F 2 Responses 1 Nov 12
me and my mom just went naked hot tubbing does that count?
NudistSooner 16-17, M 1 Response 1 Nov 15
I was at this party and everyone went naked cause we didn't have swim suits. Then things led to things and we kissed and yea. Boys and girls were there.
Carsonisthedawg1025 18-21, M 2 Nov 19
my first time was with another girl and a guy. We were all hanging out at the lake near her and she brought up the idea. We all ******** down and jumped into the freezing-*** water...
SammyRedgirl 18-21, F 2 Responses 5 a week ago
Lol I was little and my I was at my friends lake house (she is super rich, I'm not) and it was like 2am and we wanted to go in the lake (we always go swimming in the lake) but we...
liajip 13-15, F 2 Responses 4 Nov 3


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Official MINI USA Clubvan Pricing: $25,985
MotoringFile readers have a few FAQs when it comes to MINI's industrial version of the Clubman, dubbed the Clubvan. We've scoured through our previous reporting and reached out to our contacts at MINI USA to confirm the information you've been asking for, starting with the asking price: $25,985.
The asking price isn't the only question we've received, however, and the price itself has related questions that come with it.
- Does that price include the "chicken tax" on commercial vehicles? Yes it does. It also includes a $700 destination and handling charge, same as all other MINIs.
- Can I get a Cooper S or JCW Clubvan? No. Right now the Clubvan is Cooper only.
- Can't I just take the seats out of a Clubman and have the same thing? Not really. The Clubvan features steel side panels, not just vinyl covering the glass. It also features a fully flat loading floor and front safety cage.
The Clubvan was created in response to something that already exists in the marketplace. We've all seen them — small, interesting little cars with small business graphics all over them. They're either doing actual business duty, or serving simply as advertising so that the expense of the vehicle can be written off. Either way, the Clubvan now brings a little actual utility to this already common practice. Between its barn doors, flat floor and long flat panel sides, it's pretty much perfect as a small business hauler. Is it a true industrial vehicle? Of course not, but it's certainly viable as a commercial vehicle — that is, a vehicle used for commercial purposes. It'd better be, at least, given that it's subject to the dreaded "chicken tax" after all.
How about you? Any small business owners out there interested in the Clubvan for your commercial needs? Personally, I could see it as a great dog hauler!
Written By: Nathaniel Salzman
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Wakeboard, Wake Skate, Wake Surf and more...
ActiveWake is your online Wakeboard Shop offering free shipping on every wakeboard and no sales tax. Wakeboarding has never been better with huge tech advancements coming from the top brands like Liquid Force, Hyperlite, Ronix, Byerly and Slingshot.We have a huge selection of wakeboard gear that is available with fast-shipping and excellent customer service.
Slingshot Choice Wakeboard 2015
The 2015 slingshot choice is simple and affordable. With flex technology it gives you bigger pop and soft landings. Simple landings with continuous rocker and effortless transitions from edge to edge. You cant beat this price for the slingshot choice. Learn More
Liquid Force 2015 Jett
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Slingshot Recoil Wakeboard + KTV Bindings Package 2014
The Slingshot Recoil + KTV Wakeboard package 2014 was designed for riders who want a pro model setup with the pro model price tag. Learn More
Slingshot Oli Wakeboard + RAD Bindings Package 2015
the 2015 slingshot oli is a great wakeboard setup for boat and cable park. the oli has a hybrid 3-stage rocker and paired with slingshot rad bindings you feel extreme comfort. the 2015 slingshot oli rad package is the wake setup for you.. Learn More
Ronix Krush Wakeboard + Luxe Bindings Package 2014
The Ronix Krush + Luxe Women's Wakeboard Package is great for all different levels of riders. The unique shape of the Krush helps you master your edging and the comfort and style of the Luxe boots is second to none. Learn More
Slingshot Pearl Wakeboard + Jewell Bindings Package 2015
The 2015 Slingshot Pearl is easy to ride with its continuous rocker and still has the flex of a slingshot. Great for the cable park or behind the boat and is very rider friendly. The slingshot jewel looks great and with a stronger, thinner and lighter strap you get efficient tightening and better flex. Learn More
Hyperlite 2013 Marek Bio Wakeboard
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Slingshot Response Wakeboard + KTV Bindings Package 2015
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Hyperlite 2013 B-Side + Team OT Wakeboard Package
The Hyperlite 2013 B-Side + Team OT Wakeboard Package is truly a freeride masterpiece. The 2013 B-Side carries more speed into the wake than previous years models and its' 3-stage rocker provides great pop off the wake. Learn More


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He won't talk to me after our break-up, why is that?
I fell head over heals for this guy and I thought he felt the same way I did we were only dating a little over a month at first it wasn't a long distance relationship, but then it turned into one once he moved back home. He told me he was a different person at home because he is a music artist but said things wouldn't change. Once he moved back home things completely changed between us when he said things wouldn't. I would go several days without a word from him unless I made contact first and I asked him did he want o be with me and he wasn't sure because I was so far away. So I broke up with him because he wasn't even BEING my boyfriend. It was like I was in the relationship by myself..I miss him a lot and I know I didn't hurt his feelings by breaking up with him because he was so cool about the break up! Telling me to keep in touch and that what can be friends! I've called and written a few times since the break up but he doesn't respond back he is ignoring me..why is that??I NEED SOME ADVICE..WORDS OF WISDOM ANYTHING JUST TO COPE WITH THIS....
What's Your Opinion?
Most Helpful Opinion
What Guys Said 2
What Girls Said 1
It's called self-preservation. You probably did hurt his feelings, after all you were together and experienced stuff. You need to lay off and just let some time pass by, maybe he'll come around... You're upsetting both him and yourself by pursuing a friendship, so soon after the break-up.
The relationship ended 9 months ago....
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But he told me to keep in touch with him..So wouldn't you think he wanted to be friends?? And even when I suggested us being friends he said yeah we can...and now he is ignoring me and I don't understand why?
Guys wander. Don't waste your time on him, because he obviously has no plans to follow through with his promise... Sorry about that. You're better off without him.


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VIP Membership Terms: Normally $24.99 per year, but your Web Exclusive deal means you enjoy 3 months of VIP Family Benefits for $1.99. Check out your savings and benefits below.
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10:00 AM - 4:00 PM A Charlie Brown Holiday Crafts & Show
Holiday Resource List 2014
Please click here for this great list of programs.
Kentlake Drama Presents A Charlie Brown Christmas
Performance dates are: Nov. 29 (Thanksgiving Weekend) at 12pm, 1pm, 2pm & 3pm, December 4-6, December 11-13 at 7pm. Matinees at 2pm on Sat. Dec. 6 & Sat. Dec. 13.
Tickets are $5 and may be purchased at Brown Paper Tickets: http://www.brownpapertickets.com/event/920316 or at the door!
|Charlie Brown Christmas Craft Fair
Saturday November 29 | 10:00am - 4:00pm
LOTS of vendors! Start the holidays with a FUN DAY of holiday shopping! Kentlake Drama will perform "A Charlie Brown Christmas" in the KL PAC FOUR TIMES (every hour starting at Noon) on this special day!
STAMP Test
Do you speak a language in addition to English?
Can you read and write it, too?
Do you want to earn high school credit?
Upcoming Test Dates and Locations:
*January 10, 2015 - 10am Kentwood HS
Register by December 23:http://tinyurl.com/Register-RoadMap-WL-Assessment
*April 18, 2015 | 10am at Kentwood HS
Register by March 29: http://tinyurl.com/Register-RoadMap-WL-Assessment
|After School Learning Opportunities: 2:20 - 3:50
Science - Rm 1504 | Language Arts - Rm 2514
Math - Rm 1805
2014-2015 School Calendar
Please click here to view a PDF.
Late Start Dates 2014-2015
September 10 | October 1 | December 3
January 14 | February 4 | March 4April 22 | May 13 | June 3
Kentlake will host a flu immunization clinic from 3pm - 7pm
Kentlake PTSA Fundraiser
It's the season of giving, and Kent School District schools have been showing their gratitude through food drives.
Kent School District recognizes Native American Heritage Month in November.
New interim superintendent to begin immediately. KSD Board voted to approve the appointment of retired Puyallup School District Superintendent, Dr. Apostle.
The KSD Human Resources department is using new strategies to increase and strengthen the District's substitute teacher pool.
Superintendent Dr. Edward Lee Vargas represented Kent School District at the first-ever National Connected Superintendents Summit.
Sign up for free early learning classes to ensure your child is ready for school.


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Comfort Inn Ouray
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All rooms have mountain views. Half price entrance into theouray hot springs pool. Discounted telluride ski resort lifttickets. Twenty percent discoun
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8 Comments about Comfort Inn Ouray
Great place to stay. The hot tubs and the outdoor pool hotsprings were steamy even in the dead of winter. In the morning I was greeted by deer in the
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I could hardly believe what we got for $85 a night. An incredible view, a large clean room, a very comfortable bed with many fluffly pillows, and fant
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I have stayed here several times and always found the motel to be exactly what is expected with a friendly welcome added. The breakfast is adequate an
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The existing reviews are WAY OFF TRACK, this place has about as much ambiance as a hospital room, the walls were thin, the amenities are laughable, th
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The hotel was clean and quiet. Set in a beautiful location, I had a georgeous view from my window. The owners, Betty and Ted, go above and beyond the
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very simple and enjoyable stay at Comfort Inn at Ouray, Co...
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We always travel with two Yorkie furpersons, Sophie and Gracie, and we always call in advance to "make sure" a place is actually pet friendl
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We arrived late in the evening and the front desk person was warm and inviting. The check in was quick and painless. Our room was nice sized and we ha
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Who's coming and who's going. Tell us about your job move! Receive the Revolving Door Newsletter with expert analysis by email twice a week.No Revolving Door results were found.
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Raddatz Gives ABC News Insider Knowledge of Camp Liberty Murder - Posted May 13, 2009
One of the big stories this week has been the murder of five American troops by a fellow sergeant at Camp Liberty in Baghdad. ABC and CBS' led their evening newscast with the story on Monday night (it was in NBC's first block as well), but jus... [TVNewser]


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OSA supports job seekers and industry employers by providing the following services:
WORKinOPTICS.com is OSA's online job board featuring job postings from around the world and a resume bank of the field's top professionals and consultants.
OSA co-sponsors online and on-site job fairs held in conjunction with the Optical Fiber Communication Conference and Exposition / National Fiber Optic Engineers Conference (OFC/NFOEC) and the Conference on Lasers and Electro-Optics (CLEO).
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Sales Engineer | www.santec.com
Fri, 21 Nov 2014 16:00:00 EST
Regional Sales Manager | Deposition Sciences, Inc. a wholly owned subsidiary of Lockheed Martin Corporation
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Bethesda Hotel SpecialsEnjoy the best of Bethesda attractions and world-class sightseeing in Washington DC from the prime location of the American Inn, Bethesda, MD. Our warmly inviting hotel is a comforting haven just 4 miles from downtown DC and sights like the White House. Stay and explore the excitement of Washington DC, then return to our relaxing suburban location. As our guest, enjoy complimentary Continental Breakfast, free high-speed wireless Internet service, courtesy hotel shuttle around Bethesda, well-equipped Business Center, elegant meeting facilities and a luxurious outdoor swimming pool open from May-August.
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Learn How to Build a Firm Benefits FoundationSeptember 5, 2014
While health care reform hasn't gone into full swing mode yet, your business can lay a firm foundation for 2015 by following …Sponsored By Aflac
The Next Big Markets for Small Business -- China and India?
That's right, you don't need to be a massive global corporation to take advantage of emerging markets in China and … MoreMore Contributors
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Knicks Morning News (2014.11.09)
: Written by Mike Kurylo : 11-09-2014 : No Comments
[New York Post] Knicks' Iman Shumpert bounces back from Nets' debacle (Sun, 09 Nov 2014 02:58:57 -0500) ATLANTA — Iman Shumpert took plenty of the blame for Friday's loss to the Nets in Brooklyn, knowing he got schooled by former All-Star point guard Deron Williams. But Shumpert,… [New York Times] Curry Has 34, Warriors Beat Depleted Rockets 98-87 (Sun, 09 Nov 2014 05:49:10 GMT) Golden State Warriors coach Steve Kerr can't figure out how his team is still undefeated. [New York Times] Sports Briefing | Pro Basketball: Ricky Rubio of Timberwolves Is Sidelined by Sprained Left Ankle (Sun, 09 Nov …continue reading


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