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I consulted with Dr David Wilkie early September 2013 about a Labia Minora Reduction (Labiaplasty). I'm from out of Province, but I really liked how he has completed thousands of surgeries and he specialises in gynecology. Should be a winner, right?.. WRONG
I am going to just post the facts and try not to be too emotional about this whole thing.
Surgery was booked for three weeks after the consultation. I was so psychologically ready to have this done, I couldn't wait! I even put a countdown on my phone.
A local friend drove me from the private out-patient clinic to my hotel after surgery, where I slept for a good 12 hours. Pain was managed by a flexible ice pack and tylenol. (I had Tylenol 1's on hand just incase, but they weren't necessary- pain was there but manageable.)
At the one day post op meeting with Dr Wilkie, I felt really great, happy I had finally gone through with the surgery. Wilkie mentioned I was recovering remarkably well. Thank goodness I thought. One always reads about botched surgeries, but to think they could happen to me.. ludacris.
I flew home three days post op. Flying was uncomfortable, but made bearable by sitting on one of those airplane neck pillows ( the partial dounut shaped ones). Arriving home, I had a local friend pick me up, and help me get settled at home. Slept for another 12 hours.
Pre surgery I made a meal plan that would help me get on my feet faster. Two days of premade vegetable juices and smoothies really helped- I could concentrate on resting instead of cooking. I also made sure to ingest fats and protein. All was well and good for a week once home. I felt knackered and slept a lot as a result.
Eleven days post surgery, I decided to start back at work. I will never know to this day if I went back too soon, or if this was going to happen regardless. Getting dressed I felt a small, sharp pain on my left labia. I didn't think much of it at the time. As the day progressed however, the same pain constantly bothered me. I was at work, I couldn't do much. So when I got home, the first thing I did was drop my pants, grab my hand mirror, and take a look.
To my absolute HORROR the stitches had ripped mid left labia minora. My God. I had no idea what to do. I did the only thing I could think of. Straight to the University Hospital, I took a cab. Several hours of waiting later an Emergency Medical Doctor took a look. Literally 10 seconds to look. He said he couldn't do anything. He said once a stitch has popped there is no recourse but let the area heal. I started crying at this point, and he tried to console me. Apparently this area of the body has a remarkable ability to heal itself. Rest for a couple days and it should be fine, he said.
So I took another three days off work. I planted myself on my bed and didn't move except to go to the washroom and get food and water from the kitchen.
Overnight on the second day after the split (I think fourteen days post op now), the split on my left labia had grown, almost the entire left labia was split up the centre.
I was determined now. Willpower. If I stayed in one position long enough, my labia would heal properly.
I wasting over three week of my life on the bed.
It is now over 6 months post op. I only contacted Wilkie's office to book a six week post op consultation, as requested by his office on my initial consultation. I talked to the receptionist about my concerns. Instead of booking an appointment, she said Wilkie would contact me directly. (I live out of Province and stressed to her I would only want to make the trip out if Wilkie would be willing to talk revision.) Wilkie never contacted me, even after a follow up phone call to his office.
So now, I am contacting local Surgeons in Alberta. I live in Edmonton but would be willing to travel to Calgary for a revision. If there is anyone reading this who received exceptional treatment in either city, would you mind passing along the contact information of your Dr? Please and thank you, I would really appreciate it.
Trim Method Gone Wrong- 6 Months Post Op, *Not Worth It*
Yesterday I finally had a call from Dr Wilkie. I had sent recent photos of my Lady parts to show that a revision is needed. To quote Wilkie: "Everything looks normal. To look at you, I would not be able to tell you had any surgery." CLEARLY Dr Wilkie does not want to go through the headache of performing a revision. Everything does not look normal, and I am upset to say the least.
Look at the recently uploaded images. One side of my labia has completely forked down the middle. The other side is forked as well, although slightly less aggressively.
I would HIGHLY caution Ladies looking to have this surgery done, to please find a different a different doctor. I do realise mistakes happen, it is a very unfortunate mistake that my stitches completely split. But Dr Wilkie should have owned up to his mistake, instead of brushing me off like a pesky bug. The fact that he did not offer any type of recourse is telling.
Look at the recently uploaded images. One side of my labia has completely forked down the middle. The other side is forked as well, although slightly less aggressively.
I would HIGHLY caution Ladies looking to have this surgery done, to please find a different a different doctor. I do realise mistakes happen, it is a very unfortunate mistake that my stitches completely split. But Dr Wilkie should have owned up to his mistake, instead of brushing me off like a pesky bug. The fact that he did not offer any type of recourse is telling.
After talking to Dr Wilkie 6 months post, it is clear he has a blatant disregard for ownership of one's own handiwork. He has obviously washed his hands of the whole matter, despite evidence that his shoddy technique left me disfigured. Hope my review can help someone in the future. Pay it forward pls!!
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Germany's committment to Afgahan at its height was to see the deployment of over 5,000 personnel. This rather goes against their constitution.
Both Italy and Spain have suffered fatalities in the Afghan conflict too.
As for Greece, a country in grave austerity, spending ridiculous amounts on their armed forces. There's no reason why they couldn't fulfil their part in any conflict which would affect the EU. The one caveat might be, they may object to fighting along side the Turks should they ever be invited to join the EU.

subset: commoncrawl


text: On July 26, 1995, at 1730 hours Pacific daylight time, a Beech BE-77, N38062, encountered a whirlwind and ground looped while landing on runway 30 at Madera Municipal Airport, Madera, California. The airplane exited the runway and its nose gear collapsed when it struck a furrow next to the runway. The student pilot was conducting a local visual flight rules solo instructional flight and was not injured. The airplane, registered to and operated by the student pilot's flight instructor, sustained substantial damage. Visual meteorological conditions prevailed. The flight originated at Fresno Air Terminal, Fresno, California, at 1630 hours.The student pilot said in the aircraft accident report that the accident occurred on the second landing. When the main landing gear touched down, a gust of wind turned the airplane 45-degrees to the right. The student pilot said he applied left rudder, but overcorrected. The airplane began skidding down the runway and exited the runway. At the time of the accident, the surface winds were from 270-degrees at 6 knots.


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Monday, April 23, 2012
Robin Hood - Men In Tights
I own a few (dozen) movies on DVD and I have a typed list of them in a folder in a drawer somewhere.
When I look at the viewing choices available on TV for any particular day,
(AFL Game Day, Footy Flashbacks, UEFA Europa League Highlights, World of Free Sports....pfft!),
I'm often disappointed and decide to watch a DVD instead.
The choices there are easier because I've only collected things that I like to watch, things that I don't mind watching over and over. (NO SPORTS)
Like the Big Bang Theory, Criminal Minds and Bones.
(And Fringe; Warehouse 13; MacGyver; Dexter; Eureka; Stargate; Farscape and Firefly.........)
Along with the movies I've collected.
But even then, sometimes I can't decide.
So I get out the list, shuffle the pages with my eyes closed and randomly stab at a title.
Yesterday afternoon, I watched Robin Hood - Men In Tights.
Have you seen it??
It's hilarious.
(Mel Brooks was involved in the making, how could it not be funny?)
I laughed my.......well, I was going to say I LMAO, but that fatty boombah is still swaying along behind me with every step I take , so clearly I didn't, but I did laugh a lot.
I'm not going to tell you anything about the movie, I suck at reviews, but there's a little singing, a little dancing, a little mayhem......
If you haven't seen it, find a copy and watch it.
If you're anything like me, you'll laugh.
12 comments:
- Windsmoke. said...
I'm currently watching Fringe on DVD back to back episodes/seasons in the right order as Fringe was screened on t.v. out of order. Have you seen Sanctuary another good sci-fi show :-).
- April 23, 2012 at 7:16 AM
- Kim @frogpondsrock said...
Your television habits are very similar to "the Spouses" lol.
- April 23, 2012 at 7:52 AM
- The Elephant's Child said...
I refuse to watch sport - I read instead.
- April 23, 2012 at 9:56 AM
- R.H. said...
Even the footy is bait dangled by shifty advertisers but I like it because it's REAL. The shows you've mentioned are stupid. Aimed at people with no brains.
- April 23, 2012 at 11:12 AM
- Manzanita said...
I did see it years ago and I remember laughing a lot at the time.... now I can't remember much about it. My good or bad news (which ever way you look at it) is that I don't have a TV anymore. I do watch some things on the computer but I honestly never thought I would be TV'less. When my husband was alive, we had to have a TV in every room in the house.
- April 23, 2012 at 2:04 PM
- River said...
Windsmoke; I have seen some of Sanctuary, but not much. I'll catch up with it at some point.
Kim; I can count him as a friend then.
EC; I read too, but mostly I'll watch dvds.
R.H. that's me, brainless.
Manzanita; at least you have the computer to play dvds in if you choose.
- April 23, 2012 at 4:25 PM
- Tempo said...
I agree completely River, I hate sports TV..if I liked sport I'd be out there doing it. I love my collection of old movies including Robin Hood MIT which I own and watch from time to time.
- April 23, 2012 at 6:54 PM
- Red Nomad OZ said...
Hahaha! Wouldn't it be great if we could laugh our FA's off??!! I'd pick THIS movie to do it, along with 'Young Frankenstein'!!
- April 23, 2012 at 7:19 PM
- Kath said...
I've never seen it .... will add it to my 'list' of DVDs to look for when crazy sales are on.
Have you seen 'Dirty Rotten Scoundrels' - worth it just for the Ruprecht scenes!
- April 23, 2012 at 9:34 PM
Always in a dither.
One contemplates with a shiver
The doings of Maid River.
- April 23, 2012 at 11:08 PM
- The Plastic Mancunian said...
Hi River,
Not seen Robin Hood - Men In Tights - but I have seen Young Frankenstein and Blazing Saddles - great films.
BTW - I love Dexter! Currently watching Series 6 here in the UK. Wonderful.
- April 24, 2012 at 5:17 AM
- River said...
Tempo; ditto. And another thing, we have a choice of 15 channels here now, why the heck can't "they" pick two or three of those and dedicate them entirely to sport, with another one or two just for news, that would still leave ten channels to be divided up between movies, old and new, TV series, Old and new, and kids cartoons and shows.
Red Nomad; weight watchers and Jenny Craig would go out of business.I don't recall Young Frankenstein, although I have seen Young Einstein.
Kath; No, I haven't seen Dirty Rotten Scoundrels, I'll add it to my list.
Lord Rochester; I am never in a dither. Well, almost never.
Plasman; I love Blazing Saddles! I'm a bit behind on my Dexter, they've switched it to a later time slot, when I need to be asleep and I don't have a recorder. I have season 6 on my list to buy though.
- April 24, 2012 at 7:20 AM


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brand and bottle
Posted by Jennifer Sokolowski on July 8, 2011 05:00 PM
Following in the wake of the countless flavored vodkas that have been released in recent years, Bombay Sapphire has come up with a new flavor infusion of its own: Bombay Sapphire East.
Infused with lemongrass from Thailand and black peppercorns from Vietnam, Bombay Sapphire's latest release is now available in a three-market U.S. test that includes New York. While vodkas have been at the forefront of the infusion fad, Bombay Sapphire is following at least one other gin's lead: Beefeater 24, introduced in late 2008, is flavored with Chinese green and Japanese sencha teas.
A video touting the new Bombay Sapphire flavor highlights the idea of pure, hand-harvested ingredients for an authentic Eastern experience, linking in with the brand's "Infused with Imagination" campaign.Continue reading...
More about: Booze Newz, Alcohol, Bombay Sapphire, Svedka Vodka, Ricky's NYC, Clif Family Winery, Marks & Spencer
Architecture Project DirectorInterbrand Design Forum, Dayton
Resource & Financial CoordinatorInterbrand New York
Consultant, Verbal IdentityInterbrand San Francisco
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Airlines, Alcohol, Automotive, Beauty, Beverages, Branded Entertainment, Design, Corporate Citizenship, Entertainment, Fashion, Finance, Food, Healthcare, Luxury, Media, Mobile, Non-Profit, Pharma, Product Placement, Retail, Sports, Sustainability, Tech, World Cup
Tips? Ideas? Contact:firstname.lastname@example.com


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Oscars 2012 Trend Report: All that glitters is gold
A little gold statue is what brings so many starlets to the Academy Awards each year, which could perhaps explain why so many celebs decided to wear gold at this year's ceremony. Gold dominated the Oscars red carpet with several big names going all out in the metallic shade via a variety of different dress styles.
The Help's Jessica Chastain was breath-taking in a black strapless Alexander McQueen gown which featured gorgeous gold embroidery down the front and on skirt and train. With her red hair swept elegantly off her face, her choice of McQueen really couldn't be more appropriate for the occasion.
On the other end of the scale was Stacy Keibler who oozed glamour in a old Hollywood-inspired gold dress by Marchesa, which was hot off the runway from New York Fashion Week. The girlfriend of George Clooney also managed to pull off the tricky rosette on the hip which could be unflattering on anyone else.
All hail Meryl Streep! Gold was clearly a lucky colour for the legendary actress who won her third Oscar for Best Actress. One exciting aspect of her choice of Lanvin gown is that it was eco-friendly! Made from Eco Certified Fabric, her one-off dress looked divine on her and it clearly was the perfect match for her latest gold statuette.


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Regent University - Library
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Identifies key resources for education students and researchers.
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text:
1. Mitchiner JC, Schultz DS. The cost of nonurgent care for Medicaid patients in the emergency department and two community
health clinics. Abstr Book Assoc Health Serv Res Meet. 1999;16:203.
2. Wilson, KB. Health Care Costs 101. 2008 edition. Oakland, CA: California HealthCare Foundation. 2008.
4. DeNavas-Walt C, Proctor BD, Smith JC. US Census Bureau. Current Population Reports, P60-235, Income, Poverty, and Health
Insurance. Coverage in the United States: 2007.
Washington, DC: US Govt Printing Office. 2008.
5. Institute of Medicine. Insuring America's Health. Washington, DC: National Academy of Sciences. 2004.
6. Baker CD, Caplan A, Davis K, Dentzer S, Epstein AM, Frist B, et al. Health of the nation—coverage for all Americans. N
Engl J Med. 2008 Aug 21;359(8):777–80.
7. IOM. Hidden Costs, Value Lost. Uninsurance in America. Washington, DC: National Academy of Sciences. 2002.
8. Woolhandler S, Campbell T, Himmelstein, DU. Costs of health care administration in the United States and Canada. N Engl
J Med 2003;349:768-75.


text:
In this week's edition of Entertainment Weekly, the magazine highlighted "Chart Champs" who are ruling the music industry. With his last four singles, "Good Feeling", "Wild Ones", "Whistle" and "I Cry", hitting top 10 spots on the charts and selling over 10 million downloads, Flo was one of the few artists featured on the list! Check out the article to find out why he was featured in the photos below!
Latest News
February 05, 2013Filed under:
January 16, 2013
This Super Bowl weekend, Flo Rida will be kicking off Rolling Stone's Super Bowl party! Hitting the stage LIVE on February 1st at the Bud Light Hotel in New Orleans, Flo will be bringing in the Super Bowl, along with Pitbull and Nick Cannon, New Orleans style. To read more about the star-studded Super Bowl bash click HERE!
January 04, 2013
If you missed it, Flo Rida took the stage at this year's Dick Clark's New Year's Rockin' Eve on ABC! Before performing his hit singles, he sat down backstage for an interview to talk about some of his new music, acting, touring, new year resolutions, and more! Check out the full interview below!
December 25, 2012
Flo's newest album Wild Ones is now featured in Amazon MP3's "Fill Your Cloud" promotion! From today through January 31st you can purchase the album at a special price. Head to amazon.com to get your copy now!
December 21, 2012
Flo recently hit the WWE ring to perform for their 10th annual holiday TV special! If you missed the "Let It Roll" and "Wild Ones" performance, tune in to WWE's Tribute To The Troops tomorrow night at 9pm on NBC!
December 19, 2012
Music Choice recently released their "Best of List" featuring 100 of the best artists and songs over the year including Flo Rida for three different songs! Music Choice recognized "Whistle", "Good Feeling" and "Wild Ones" featuring Sia as some of the best songs of 2012. Head to musicchoice.com to find out more about the MC 100 Best of List now!


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IAS 29 — Financial Reporting in Hyperinflationary Economies
IAS 29 Financial Reporting in Hyperinflationary Economies applies where an entity's functional currency is that of a hyperinflationary economy. The standard does not prescribe when hyperinflation arises but requires the financial statements (and corresponding figures for previous periods) of an entity with a functional currency that is hyperinflationary to be restated for the changes in the general pricing power of the functional currency.
IAS 29 was issued in July 1989 and is operative for periods beginning on or after 1 January 1990.
History of IAS 29
|November 1987
|Exposure Draft E31 Financial Reporting in Hyperinflationary Economies
|July 1989
|IAS 29 Financial Reporting in Hyperinflationary Economies
|1 January 1990
|Effective date of IAS 29 (1989)
|IAS 29 was reformatted
|22 May 2008
|IAS 29 amended for Annual Improvements to IFRSs 2007
|1 January 2009
|Effective date of the May 2008 revisions to IAS 29
Related Interpretations
- IAS 21 superseded SIC-19 Reporting Currency – Measurement and Presentation of Financial Statements under IAS 21 and IAS 29
- IAS 21 superseded SIC-30 Reporting Currency – Translation from Measurement Currency to Presentation Currency
- IFRIC 7 Applying the Restatement Approach under IAS 29 Financial Reporting in Hyperinflationary Economies
Amendments under consideration by the IASB
Summary of IAS 29
Objective of IAS 29
The objective of IAS 29 is to establish specific standards for entities reporting in the currency of a hyperinflationary economy, so that the financial information provided is meaningful.
Restatement of financial statements
The basic principle in IAS 29 is that the financial statements of an entity that reports in the currency of a hyperinflationary economy should be stated in terms of the measuring unit current at the balance sheet date. Comparative figures for prior period(s) should be restated into the same current measuring unit. [IAS 29.8]
Restatements are made by applying a general price index. Items such as monetary items that are already stated at the measuring unit at the balance sheet date are not restated. Other items are restated based on the change in the general price index between the date those items were acquired or incurred and the balance sheet date.
A gain or loss on the net monetary position is included in net income. It should be disclosed separately. [IAS 29.9]
The restated amount of a non-monetary item is reduced, in accordance with appropriate IFRSs, when it exceeds its the recoverable amount. [IAS 29.19]
The Standard does not establish an absolute rate at which hyperinflation is deemed to arise - but allows judgement as to when restatement of financial statements becomes necessary. Characteristics of the economic environment of a country which indicate the existence of hyperinflation include: [IAS 29.3]
- the general population prefers to keep its wealth in non-monetary assets or in a relatively stable foreign currency. Amounts of local currency held are immediately invested to maintain purchasing power;
- the general population regards monetary amounts not in terms of the local currency but in terms of a relatively stable foreign currency. Prices may be quoted in that currency;
- sales and purchases on credit take place at prices that compensate for the expected loss of purchasing power during the credit period, even if the period is short;
- interest rates, wages, and prices are linked to a price index; and
- the cumulative inflation rate over three years approaches, or exceeds, 100%.
IAS 29 describes characteristics that may indicate that an economy is hyperinflationary. However, it concludes that it is a matter of judgement when restatement of financial statements becomes necessary.
When an economy ceases to be hyperinflationary and an entity discontinues the preparation and presentation of financial statements in accordance with IAS 29, it should treat the amounts expressed in the measuring unit current at the end of the previous reporting period as the basis for the carrying amounts in its subsequent financial statements. [IAS 29.38]
- Gain or loss on monetary items [IAS 29.9]
- The fact that financial statements and other prior period data have been restated for changes in the general purchasing power of the reporting currency [IAS 29.39]
- Whether the financial statements are based on an historical cost or current cost approach [IAS 29.39]
- Identity and level of the price index at the balance sheet date and moves during the current and previous reporting period [IAS 29.39]
Which jurisdictions are hyperinflationary?
IAS 29 defines and provides general guidance for assessing whether a particular jurisdiction's economy is hyperinflationary. But the IASB does not identify specific jurisdictions. The International Practices Task Force (IPTF) of the AICPA's Centre for Audit Quality monitors the status of 'highly inflationary' countries. The Task Force's criteria for identifying such countries are similar to those for identifying 'hyperinflationary economies' under IAS 29. From time to time, the IPTF issues reports of its discussions with SEC staff on the IPTF's recommendations of which countries should be considered highly inflationary, and which countries are on the Task Force's inflation 'watch list'. The IPTF's meeting notes from the 19 November 2013 meeting state the following view of the Task Force:
Countries with three-year cumulative inflation rates exceeding 100%:
- Belarus
- Islamic Republic of Iran
- South Sudan (although South Sudan only became independent of Sudan in July 2011 and data is not yet available to calculate a three-year cumulative inflation rate, the three-year cumulative inflation rate is projected to be 129% by the end of 2013)
- Venezuela
- Sudan
Countries where the three-year cumulative inflation rates had exceeded 100% in recent years:
- Democratic Republic of Congo
Countries (a) with projected three-year cumulative inflation rates between 70% and 100%; (b) where the last known three-year cumulative inflation rates previously exceeded 100% and current actual inflation data has not been obtained; or (c) with a significant increase in inflation during the current period
- Ethiopia
Other countries noted in the report:
- Argentina - although no data has been observed to date that would support Argentina being considered highly-inflationary in 2013, the official data since 2008 shows considerably lower inflation rates than alternative data sources; the IPTF encourages additional disclosures by entities that have significant operations in Argentina


text:
Ten-year-old Zoe McDonough died July 5, 2012, in a boating accident on Lake Chickamauga.
Photo by Contributed Photo /Chattanooga Times Free Press .
published Saturday, June 1st, 2013
Stories this photo appears in:
Q. Whatever happened to Brett McDonough, whose mother and daughter died in a Chickamauga Lake boating accident on July 5 last year?


text: >From: Contesavan at aol.com >Full-name: Contesavan >Date: Sun, 8 Sep 2002 15:19:00 EDT >Subject: DEMO >To: Wiesenfeuer at egroups.com, namron at ansteorra.org, northern at ansteorra.org >CC: cw at cyberstation.net, mg1m at swbell.net, >mooneschadowe_seneschal at ansteorra.org, > tadhg at ou.edu, herring at upperspace.net, rundel_seneschal at yahoo.com, > jhamen at yahoo.com, aelfwyn at coxconnect.net > >Greetings, >There will be a Renaissance Festival on October 26 and 27 in Guthrie, >Oklahoma. As many of you may already know, this is the same weekend as >Samhain. This year Eldern Hills has graciously moved their event to Camp >Cimmaron just a few miles from Guthrie. This should give everyone an >opportunity to participate at both the event and the demo. >The location of the festival is the Guthrie Scottish Rite temple. This >building was the former state capitol building. It is magnificent! The >building itself is a must see. And there will be guided tours of the >building all weekend. If you simply cannot wait for a glimpse inside, take >the virtual tour on line. >Yes, we need fighters! Yes, we need singers and dancers. Yes, we need your >support to make this a glorious Demo! >For further information please check out the website at >http://guthriescottishrite.org under Reunion or take a tour through the >building. >If you should have any questions, please let either Delphina or me know. We >will be looking forward to seeing you there. > >In service, >Vanessa > >contesavan at aol.com > >or > >Karadelp at aol.com


text:
Psychological, physical and personal rights injuries are in connection with the area of law that personal injury lawyer is practicing. Mainly involving law of torts, a personal injury lawyer focuses on handling cases associated with insurances, personal/life insurance, medical claims, auto insurance, industrial injuries, workmen's compensation, employment issues, breach of duty, negligence, defamation, etc. Hence, a personal injury lawyer also referred to as the plaintiff lawyer could be representing his clients or the unwilling recipient of an injury for not only physical impairment or psychological distress but also violation of his legal rights against a person, firm, enterprise or a government authority for monetary and non-monetary compensation and damages. Personal injury attorney
A personal injury lawyer, primarily and basically concentrates on getting compensation for the victim of personal injury, and can have the case resolved outside of court with an adversary in place of going to court trial, as a speedier way of obtaining justice and relief to his client. The situations in which a mutual settlement is not attained, a court action ensues, in which the expertise of such a specialist is useful. It'll be easier to handle the settlement when the lawyer has adequate knowledge on the legislation, can manage and control your situation as well as posses excellent inter-personal relationships. Free personal injury articles
Personal injury laws vary in each and every country. To become a graduate in law, you have to possess a specialization in a particular law, even if they can work as a personal injury lawyer.


text:
Skinny Slow Cooker Southwest Chicken Soup
I have one last healthy recipe for you before Skinny January comes to an end. It's like I took a plate of my favorite Mexican food and turned it into a fantastic bowl of soup! This is one of those meals you will make over and over again; the kind of recipe that satis...Read More and Get the Recipe!


text:
The Solar Heating and Cooling European Map
Promoting the use of Solar Heating and Cooling by making visible existing installations near you!
Are you aware of any solar thermal system for domestic or other applications?
Add your example to the map! More details here
2013 European Solar Thermal Market
Solar heating and cooling technology roadmap
The Solar Keymark a to z
Solar keymark: THE Quality Label for Solar Thermal Products in Europe
A new brochure to help boost your solar thermal business
The Solar Keymark was developed by the European Solar Thermal Industry
Federation (ESTIF) and CEN (European Committee for Standardisation)
in close co-operation with leading European test labs and with the support of the European Commission.
It is the main quality label for solar thermal products and is widely spread across the European market and beyond.
Please click here to download your copy of the brochure. Now also available in several languages.
solar thermal potential in europe
The potential of solar thermal in Europe
To provide the European Union and its Member States with substantiated information on the contribution solar thermal can make to the 20% renewable energy target set by the RES Directive (2009/28/EC), detailed surveys were conducted in five representative countries: Austria, Denmark, Germany, Poland, Spain. The information gathered was then extrapolated to the 27 EU countries and the future heating and cooling demand was calculated for 2020, 2030 and 2050, taking into account a decline of the overall energy demand due to energy efficiency measures.
Please click here to download the full study and the different versions of the executive summary.
European Solar Days 2014: 1 - 18 May
The European Solar Days successfully promote the use of a free unlimited renewable energy source available everywhere to everyone to generate electricity as well as heating and cooling: the SUN.
They are celebrated in an increasing number of countries and in 2012 around 8000 events were held in 20 European countries by diverse organisations ranging from solar equipment manufacturers to schools and local authorities.
Solar Keymark: A certification scheme for Europe
The Solar Keymark is widely recognised in solar thermal support programmes throughout Europe.
The mark certifies the conformity of a solar thermal collector or system to the relevant European Standards
(EN 12975 or EN 12976).
For information on how to obtain the Solar Keymark, please see www.solarkeymark.org
A Strategic Research Agenda for solar thermal
Making solar thermal products even better
and work in more applications. This is the solar thermal sector's goal.
Industry and researchers have come together in the European Solar Thermal Technology Panel (ESTTP) to identify the needs of solar thermal R&D.
Among the top priorities are compact heat storages, solar thermal for industrial processes, and solar cooling. With the right kind of research solar thermal can be used for much more than just heating houses or sanitary water.
Visit the website of the European Technology Platform on Renewable Heating and Cooling to learn more about the future of solar thermal technologies
Solar Thermal News
Winner of Video Research Competition 2014Date : 29/10/14
The winner of solarthermalworld.org's Video Research Competition 2014 is Jakob Berg Johansen, Research Assistant at the Technical University of Denmark, Department of Civil Engineering, Section for Building Energy.More
EU 2030 energy and climate targets: The right regulatory framework will lead us way beyond 27% for renewables!Date : 24/10/14
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|Record Abstracts, Subgroups Promise Full Meeting
A record 3,128 were submitted for the August deadline for the 42nd ASCB Annual Meeting this year, to be held in San Francisco from December 14-18. An additional 200 abstracts are anticipated for the late submission deadline of October 15. Member-organized subgroup applications also exceeded previous years' submissions substantially: twenty-three Special Interest Subgroups will be held on Saturday, December 14.
|Special Interest Subgroups
The following member-organized sessions were selected by the ASCB Program Committee for presentation at the ASCB 42nd Annual Meeting in San Francisco. All Annual Meeting registrants are welcome to participate; no separate registration is required. All subgroups will be held at the Moscone Convention Center, from 1:00 PM 5:30 PM on Saturday, December 14. Speakers and room numbers are posted in the Annual Meeting Program.
Actin in the Nucleus
Monomeric (or low assembly state) actin was long thought to enter the nucleus passively, as a "thermodynamic wanderer". But now, there is growing evidence for functional actin in the nucleus, as well as actin-related proteins and myosin.
Automated Interpretation of Fluorescence Microscope Images
Fluorescence microscopy is widely used to study cellular systems, but only recently have significant efforts been made to create fully automated systems for the interpretation of resulting images. Interpretation in this context means going beyond quantitating and describing specific images to building models of cellular processes that are driven by image data.
Building the Cell II: Development of Complex Structures in Single Cells
Modern cell biology has made great strides in understanding cell structure and function. As with any engineering problem, however, there is a third important aspect that needs to be understood besides structure and function, and that is assembly. How are the complex structures found within the cell specified? Last year's Building the Cell session focused on reducing the problem down into the most general and fundamental processes of morphogenesis (control of size, position, etc.). This year we will extend the discussion to the bigger picture and examine the generation of specific cellular structures. Studies on cellular morphogenesis have been hampered in multicellular organisms by issues of cell-cell interactions, such as adhesion, that impinge on cell structure. Discussion will concentrate on development of structure in single-celled organisms, for which cell autonomy is guaranteed.
Cell Biology of Cell Protrusions
Cell protrusions are extensions of cell edges that are formed either as discrete, fingerlike projections (filopodia, spikes or microspikes, podosomes) or as broader sheets (lamellipodia, invadopodia, pseudopodia). Although identified microscopically over many years on oocytes, cells of early embryos, cultured cells and neuronal growth cones, progress in understanding the structure, regulation and function of cell protrusions has been limited by their morphological diversity, transient and dynamic nature, sensitivities to fixation and a lack of molecular markers. In addition, research into cell protrusions is currently found scattered in different disciplines (eg, cell adhesion, actin cytoskeleton, neurobiology). The session will address a perceived need for a forum to bring currently active researchers together, at a time when studies of protrusions in a number of different systems are sufficiently advanced to enable meaningful discussion and comparison. The session aims to 1) raise recognition of cell protrusions as entities of cell structure and function; 2) facilitate and focus discussion of shared or distinct aspects; 3) identify open questions and directions ripe for future study.
Cell Signaling Pathways Required for Skeletal Development and Maintenance of Bone Architecture
Regulatory factors required for the commitment and differentiation of osteogenic stem cells during embryonic development are obligatory for the continued renewal of bone throughout life. Many of these factors initiate cascades that signal renewal of the bone forming osteoblasts and the bone resorbing osteoclasts, as well as integrate activities to support bone tissue remodeling in response to physiologic cues. The session will focus on the transduction of physiological signals from the extracellular matrix to the nucleus for the activation and suppression of skeletal gene transcription. There is a necessity to characterize the molecular mechanisms by which multiple signaling pathways converge to coordinate bone phenotype restricted expression. Regulatory parameters that are operative for osteoblast and osteoclast differentiation, and for cellcell and cell-matrix interactions, have become important paradigms for identifying components of the mechanotra induction pathways, pathways that are mediated by the Smad/TGF/ beta super family as well as by MAP kinase and tyrosine kinase signaling pathways that mediate activities of tissue-specific transcription factors.
Four invited speakers will present state of the art reviews of molecular mechanisms by which major signal transduction pathways elicit tissue specific responses in skeletal cells. Others wishing to present material should contact the organizer.
Cell-Cell Fusion
Computational Cell Biology with the Virtual Cell
The Virtual Cell is a computational tool for developing simulations of cellular processes within the actual three-dimensional geometry of experimental cells. Use of the Virtual Cell technology has recently been applied to a number of cellular modeling studies (e.g. Fink et al., 2000. Biophysical Journal. 79:163183; Smith, et al., 2002. Science 295:488-491). Developed by the NIH-designated National Resource for Cell Analysis and Modeling (NRCAM), the Virtual Cell technology is freely accessible to the academic scientific community from a central server (www.nrcam.uchc.edu). Designed specifically for cell biologists, the software allows input of biochemical reactions and species, membrane channels and pumps, and macromolecular structures along with the associated cellular geometries in the form of segmented images. Once a physiological model has been developed, the system transparently generates a mathematical model that can subsequently be used to simulate complex behavior. If desired, the mathematical model can be directly input or edited via the math model interface. Models and simulations are subsequently stored in a dedicated database; models can be maintained as private or shared among research groups or the general public. The session will begin with an overview of the Virtual Cell as a tool for computational cell biology and examples of its use, followed by a walkthrough of its design and user interface. A bank of laptop computers will be provided to allow interested researchers to explore the software with the aid of several of the developers using preloaded tutorials and models. Supported by grant RR13186 from the National Center for Research Resources.
Cytoskeletal Pharmacology and the Role of Cytoskeletal Proteins in Human Disease
The cytoskeleton is a diverse, multi-component framework that plays a fundamental role in many cellular activities in cluding mitosis, cell division, intracellular transport, cell motility, muscle contraction, and the regulation of cell polarity and organization. Cytoskeletal proteins have been implicated in the etiology or pathogenesis of a wide variety of diseases including cancer, cardiovascular disease, inflammatory disease, fungal, bacterial and viral infections, and neurodegenerative disease.
This implication arises from linkages between mutations in cytoskeletal genes and human disease and from the use of pharmaceuticals that bind to cytoskeletal proteins and modulate their function. Well-known examples of such drugs include the taxanes and vinca alkaloids, both examples of anti-mitotic agents that modulate microtubule dynamics.
While the taxanes and vinca alkaloids have served as the cornerstones of modern chemotherapy since their introduction 20 years ago, their use is severely constrained by dose-limiting toxicities related to the broad role that tubulin plays in important cellular processes unrelated to mitosis. However, the rapid growth in the field of cytoskeletal research is leading to the identification and characterization of cytoskeletal proteins that, unlike the ubiquitous tubulin, play specific roles in critical cell processes and, therefore, may be potential targets for improved therapies.
The goal of this session is to inform and stimulate discussion around the role of cytoskeletal proteins in normal cell biology and in disease as well as the evidence that small molecule intervention in cytoskeletal function may have therapeutic application. Supported by an Education Grant from Cytokinetics Inc.
Embryonic Stem Cells
Mouse embryonic stem (ES) cells are becoming a very powerful developmental model in which to study commitment and lineage progression not only in animals but also in an in vitro setting. For example, studies on more than 20 different and diverse lineages have been reported over recent years. The intention of this session is to highlight the utility and potential of this ES cell-based in vitro approach by bringing together some recent developments in a few selected lineages.
Emerging Environmental Contaminants: A Role for Cell Biology?
Every day the media assails us about some environmental catastrophe or previously unsuspected environmental contaminant. Notable examples just this past year range from detection of pharmaceuticals in the aquatic environment, finding high levels of Scotchgard in polar and oceanic animals and the discovery that PPB levels of the herbicide atrazine causes hermaphroditism in frogs. This information often does not lead to policy changes because there is no mechanistic basis for how these chemicals can have harmful biological effects at such low levels. This session will bring together cell biology research describing how efflux transporters that act as first lines of defense against xenobiotics can be compromised by anthropogenic chemicals, how PPB levels of agricultural or industrial chemicals can effect sex change or chromosome disjunction and how these chemicals can alter cell function and developmental fate. There is a paucity of cell biological research in these areas and this session will showcase how good science can make a difference in understanding the observed phenomena and hopefully effect rational policy decisions.
Emerging Roles for the Tight Junction
Tight Junctions are a hallmark of polarized vertebrate epithelial cells and long recognized for their ability to create intercellular barriers to paracellular transport. More recently, additional roles for the TJ have been established in cell polarity, vesicle targeting, cell-cell signaling and human disease. This session will highlight these recent insights and their molecular basis.
The Endocytosis and Trafficking of Caveolae/raft Domains
Caveolae are smooth invaginations of the plasma membrane rich in cholesterol and sphingolipids that form a subclass of detergent insoluble membranes or glycolipid rafts. Caveolae are distinguished from rafts not only by their invaginated morphology but also by the association of stable plasma membrane caveolae with caveolin. However, it is becoming increasingly clear that raft domain heterogeneity extends beyond caveolin association. Heterogeneity of these domains extends to their lipid composition as well as their functionality in signaling, plasma membrane distribution and endocytosis. Plasma membrane associated rafts and caveolae are cell surface signaling platforms but might also act to regulate signaling by sequestering or segregating signaling molecules. Both caveolae and rafts have been implicated in endocytosis and caveolae/ raft-mediated endocytosis can be defined as clathrin-independent and dynaminand cholesterol-dependent. However, the extent to which caveolae and raft endocytic pathways are distinct remains to be addressed as do the apparently opposing roles of caveolin as a stabilizer of cell surface caveolae and as an inducer of caveolae-mediated endocytosis. Caveolae-mediated endocytic pathways target both the endoplasmic reticulum and the Golgi apparatus and can be mediated by a caveolinpositive endosomal compartment. This session will address and discuss the varied and multiple aspects of caveolae/raft trafficking in the cell.
Gap Junctions
Deficient or improper gap junction function has recently been associated with a variety of disease states including some forms of neuropathy, hereditary deafness, cataracts, skin disease, heart disease, and cancer. This session will include presentations of recent developments regarding the cellular and molecular biology of gap junction proteins (connexins) including the following areas: channel regulation/properties, consequences of intercellular communication, connexin trafficking/ gap junction assembly, and developmental studies in knockout mice.
Intermediate Filaments: Novel Roles in Cellular Physiology and in the Organization of Nuclear Architecture
For many years intermediate filaments (IF) were seen as strictly structural non-dynamic cytoskeletal components, with functions only relevant to the response of cells to mechanical stress. However, this vision of IF has been put to rest by the recent findings that they are dynamic entities both within the nucleus and the cytoplasm. A plethora of recent findings demonstrates that IFs are moving toward center stage with respect to metazoan cell physiology. In particular the involvement of the nuclear lamins in DNA replication and in transcription, has made it evident, even to the hardest-core molecular biologist, that an understanding of IF structure and function has now become a pressing need. This is further emphasized by the recent findings that point mutations in the human nuclear lamin A gene can give rise to a wide spectrum of different diseases ranging from cardiomyopathy and muscular dystrophy to lipodystrophy. Likewise, mutations in genes encoding members of all four classes of cytoplasmic IFs are known to cause diseases ranging from nervous system disorders to blistering diseases of the skin. These findings taken together with new insights into the structure of IF proteins at atomic resolution, their assembly, their remarkably diverse motile properties, and their molecular motor-mediated incorporation into the cytoskeleton of living cells, makes them a valuable model for carrying out a variety of cell biological studies.
Mitotic Defects in Cancer Cells
Genomic instability is increasingly recognized as a key component of tumorigenesis. One source of instability is segregational mistakes caused by defects in the assembly or function of the mitotic apparatus, or the inability of chromosomes to properly associate with the spindle. Abnormalities in cell cycle checkpoints exacerbate these problems by preventing the pause needed for repair or compensation. This session describes and discusses some recent developments in identifying and understanding the defects in cancer cells causing the failure to accurately segregate the chromosomes.
Monomeric GTPases Regulating Intracellular Protein Traffic
Monomeric GTPases that belong to the Ypt/Rab and Arf families are key regulators of intracellular protein traffic. Recently, members of the Rho GTPase family were also suggested to regulate protein traffic. In the exocytic, endocytic and retrograde pathways both proteins and membrane are transported between intracellular organelles via vesicles or tubules that are formed at one compartment and fuse with the next. Monomeric GTPases are molecular switches that cycle between the GDP-and the GTPbound states. When in the GTP-bound state, GTPases interact with effectors that carry out the various functions required for vesicular transport. Work in recent years has uncovered a role of some members of these three families in the many steps of the protein transport pathways. GTPase interactors that serve as nucleotide-cycling regulators or downstream effectors have also been identified. These studies suggest some basic mechanisms by which GTPases regulate individual transport steps. The mechanisms range from sorting cargo in forming vesicles, through actual vesicle formation, movement, and docking, to membrane remodeling and fusion. In addition, new evidence suggests that crosstalk between monomeric GTPases might serve in the coordination of individual transport steps. This session will discuss 1) new mechanisms by which monomeric GTPases regulate vesicular transport, 2) novel ideas about the role of these GTPases in the coordination of different transport steps, and 3) the possible role of GTPases in the coordination of protein transport with other cellular processes.
Central to the form and function of muscle are the myofibrils, membranous components and the cytoskeleton that provide the structure, the contractile force and regulation. The challenges of identifying the essential steps involved in these processes and understanding how the myofibrillogenesis is initiated and controlled are still unmet. This session will present nine short presentations on the latest advances in the study of myofibrillogenesis. Supported by an Educational Grant from the Universal Imaging Corp.
New Techniques for Studying Living Cell Dynamics
Several new techniques for studying living cell dynamics have emerged during the past two years. Six of these will be presented in this session. New self-referencing biosensors that can detect oxygen and glucose fluxes across single cells with exceptional spatial resolution will be described. These probes reveal the dynamics of molecular transport by detecting gradients in the extended boundary layer surrounding a single cell. This approach is complemented by a new technique to be presented called PEBBLES for optical chemical imaging of oxygen and other molecules inside living cells. Two other approaches for studying intracellular dynamics will follow, and several applications for quantum dots and fluorescence correlation microscopy for imaging RNA trafficking will be presented. New approaches for detecting both intracellular molecule movements and membrane dynamics, including the application of GFP-labeled probes of membrane microdomains (rafts) will be described. Results using Second Harmonic Generation Microscopy for probing both intrinsic proteins and extrinsically applied voltage-sensitive dyes in living cells will be presented. Supported by an educational grant from the NIH National Center for Research Resources through the BioCurrents Research Center.
Protein Modules in Cytoskeletal and Signalling Molecules
The functional plasticity of protein modules is of enormous cell biological relevance and covers a broad spectrum of fields both closely and more distantly related to cell biology. The field embraces both structural and cell biological approaches, but is also highly relevant for the establishment of precise annotation catalogs of genomic data and is thus of interest for the emerging field of "in silico cell biology".
The recent progress in protein research, made possible by the developments in structural, molecular and cell biology over the past five years, has demonstrated that proteins use a set of modules, copies of which can be found in sometimes diverse and seemingly unrelated molecules to perform specific cellular functions. However, despite sometimes striking structural conservation, the in vivo functions for certain protein modules can differ quite dramatically and in some cases result from only subtle amino acid substitutions. It thus appears that a significant number of proteins (and functions) has been generated through evolution by creatively using variations of established building blocks and by combining such functional modules at differing positions and varying copy number to create functional diversity. The purpose of this session is to bring together and unify the different ideas and approaches currently employed to study the structure/function relationship of protein motifs (or modules) to enhance the generation of new and refined concepts and working models. We will focus on protein modules present in both cytoskeletal and signaling molecules. To date a minimum of eleven individual, structurally unrelated, functionally thoroughly investigated (and in some cases crystalized) protein modules are shared between these two protein families. These include domains implicated in cytoskeletal association, phospholipid binding, polyProline recognition, membrane targeting, Ca2+-regulation or GTPase activation.
Proteomics in Cell Biology
A combination of proteomic assay with cell biology analyses will shed light on understanding of protein-protein interaction networking in a variety of cellular processes.
Quantitative Network Biology of the EGF Receptor System
The EGF receptor probably is one of the most intensely studied receptor systems. For more than 20 years, computational models have been used to analyze EGF receptor dynamics and interpret mutational studies. They are now being used to understand even more complex processes including signal transduction, autocrine loops, and developmental patterning. This session will bring together experts who are examining different aspects of the EGF receptor system, such as ligand production, intracellular trafficking, and signal transduction and who are using a variety of different approaches, such as cell engineering, image analysis, and site-directed mutagenesis. How to integrate a wide diversity of both quantitative and qualitative data into a higher-order understanding of overall system behaviour will be a major focus of discussion, particularly with regard to information processing by cells. The EGF receptor could serve as an excellent example of how models and experiments can be combined productively to understand complex biological processes.
The Spindle Matrix: Herring or Harbinger?
Spindle bipolarity underlies accurate transmission of chromosomes at cell division. Spindle bipolarity across species requires the activity of kinesins in the BimC family; spindles are monopolar in BimC deficient mutants rather than bipolar. Concomitant loss of Kar3 kinesin function restores spindle bipolarity. Translocation of the motor domains of BimC and Kar3 kinesins toward the plus and minus ends of microtubules, respectively, suggested that spindle bipolarity could be explained by application of antagonistic motive forces to spindle microtubules. Recent work showed that the BimC kinesin Eg5 remains statically positioned in spindles as microtubules flux poleward, as if tethered to an immobile spindle matrix rather than to dynamic spindle microtubules. The very existence, let alone functional significance, of a spindle matrix is controversial as is the concept of interactions between BimC kinesins and nonmicrotubule binding partners. Identification and genetic analysis of spindle matrix candidates like skeletor in Drosophila affords a means to dissect the spindle matrix and its role in spindle bipolarity. This session will reexamine evidence for a spindle matrix and its function in spindle organization.
Systems Biology and the Cell: Are There Simple Rules Governing Complexity?
Cell biologists have long been concerned with defining relationships between cell structure and function. As the world of genomics allows rapid molecular identification of protein assemblies, the prospect of dissecting higher order protein machines and obtaining quantitative information about their mechanics has improved. In this session, the question of what types of simple rules might operate in subcellular systems, what is the minimal information required to create predictive models, and some of the systems in which such modeling might produce immediate and valuable information will be discussed. One goal of the session is to juxtapose talks describing complex networks involved in different aspects of cellular behavior to identify similarities, and to discuss how to extract (reverse engineer?) simple rules from complex datasets derived from biological processes.
Use of RNAi and Other Expression Inhibition Methods in Vertebrate Cell Biology
The ability to target individual genes with RNAi and related methods is revolutionizing the study of eukaryotic gene function. Although much of the work on understanding and using RNAi has come from genetic systems in which there exists the means to readily construct and identify mutations, the real power of the technique will be in systems that do not have such means. For the first time it is possible to reduce or eliminate the expression of particular proteins of interest in vertebrate cells, without having to go through the very laborious construction of deletion mutations. We are only just beginning to understand the important parameters for the use of this technique in vertebrate cells. This session will focus on recent methodological advances, such as expression of RNA hairpins, in vitro creation of small interfering RNAs from larger transcripts in vitro, and on interesting uses of the technique, such as targeting multigene families, and large scale screening.
|Members In The News
James Rothman of the Sloan-Kettering Institute, an ASCB member since 1982, and Randy Schekman of the University of California, Berkeley, an ASCB member since 1984 and President in 1999, received the 2002 Albert Lasker Award for Basic Medical Research.
Sarah Elgin of Washington University, an ASCB member since 1974 and co-Editor-in-Chief of Cell Biology Education, Elizabeth Jones of Carnegie Mellon University, an ASCB member since 1983, and Tim Stearns of Stanford University, an ASCB member since 1994, were among 20 scientists dedicated to undergraduate science teaching to be named the first Howard Hughes Medical Institute Professors.
Roger Davis of the University of Massachusetts Medical School, an ASCB member since 1992, was elected to the Royal Society, the UK's national academy of science.
Joan Steitz of Yale University, an ASCB member since 1983, received the 2002 Lewis S. Rosentiel Award from Brandeis University.
David Botstein of Stanford University, an ASCB member since 1985 and founding Editor-in-Chief of Molecular Biology of the Cell, will become the Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University.
John B. Lowe of the University of Michigan Medical School, an ASCB member since 1986, was elected a 2002 fellow of the American Association for the Advancement of Science.
H. Robert Horvitz of the Massachusetts Institute of Technology, an ASCB member since 1988, received the 2001 Genetics Society of America Award.
Purnell Choppin, HHMI President Emeritus and an ASCB member since 1972, received an honorary doctorate of humane letters from The Johns Hopkins University at its 2002 commencement.
Pamela Bjorkman of the California Institute of Technology, an ASCB member since 1994, and Judith Kimble of the University of WisconsinMadison, an ASCB member since 1991, were elected to the American Philosophical Society.
Cornelia Bargmann of the University of California, San Francisco, an ASCB member since 1995, was elected to the fellowship of the American Academy of Arts and Sciences.
Joan Massagué of the Memorial Sloan-Kettering Cancer Center, an ASCB member since 1997 and the 2000 ASCB Porter Lecturer, received the 2002 Howard Taylor Ricketts Award from the University of Chicago.
Richard P. Lifton of the Yale University School of Medicine, an ASCB member since 1998, received the 2002 Richard Bright Award from the American Society of Hypertension.
Elaine Fuchs of the Rockefeller University , an ASCB member since 1980 and President in 2001, and Gerald Rubin of the Howard Hughes Medical Institute, an ASCB member since 1990, were named "Biotech Geniuses to Watch" by Discover magazine.
|Undergraduate Students
The Education Committee would like to highlight undergraduate science at the ASCB Annual Meeting in December and to provide a time when students can network with other undergraduates who are authors on posters at the meeting. These undergraduate students are invited to meet in Room 252 of the Moscone Convention Center on Saturday, December 14 at 5:30 pm immediately following the Student Program and MAC Mentoring Symposium.
|Collins, Cravatt to Receive ASCB-Promega Award
Kathleen Collins of the University of California, Berkeley, and Benjamin Cravatt of the Scripps Research Institute will receive the fourth annual ASCB-Promega Award for Early Career Life Scientists at the ASCB Annual Meeting in December.
Collins' research has focused on ribonucleoprotein (RNP) reverse transcriptase telomerase. She is studying telomerase both in vitro, to elucidate the novel structure and biochemical mechanisms of this unique reverse transcriptase, and in vivo, to investigate telomerase function and regulation in the cell.
Cravatt is being recognized for his research with fatty acid amides in cellular and organismal biology. Fatty acid amides, a family of chemical messengers, have been shown to affect many physiological functions, including sleep, thermoregulation, pain sensitivity, and angiogenesis.
The Award lectures will be presented on Tuesday, December 17.
|Free CV Posting on New Job Board
ASCB members may post their CV on the new ASCB Job Board. The Board has enjoyed heavy traffic by prospective employers since its launch last summer. Posting is an exclusive privilege of ASCB membership.
The Job Board provides a searchable database for jobs and employee recruitment. The year-round service provides job seeker profiles and CVs. The Board also provides employer profiles, recruiter profiles and job listings. Members or non-members may search and view listings for free.
A Job Board listing of 200 words costs employers $200 for a three-month period; it may be extended for three months at no additional cost.
|Recommendations of the National Research Council's Committee on Science, Engineering & Public Policy (COSEPUP) on Enhancing the Post-Doctoral Experience
Award institutional recognition, status, and compensation commensurate with the contributions of postdocs to the research enterprise.
The ASCB is grateful to the following members who have recently given gifts to support Society activities:
Josephine Adams
|Grants & Opportunities
NSF Planning and Research Grants. Frontiers in Integrative Biological Research (FBIRE) program. Preliminary Proposals due November 1. Planning grant proposals due November 12.
Royal Society. The Royal Society invites nominations for a new award in honor of Rosalind Franklin, who discovered and proved the double helical structure of DNA by X-ray crystallography.
2003 Cooperative Grants Program. The U.S. Civilian Research and Development Foundation (CRDF), invites teams of U.S. and former Soviet Union (FSU) scientists and engineers to apply for oneto twoyear grants.
|Career Opportunities
Biology Lecturer. Instructional responsibilities will include undergraduate teaching in introductory biology, genetics, and possibly pharmacology, biochemistry, and/or microbiology, depending on the qualifications of the candidate. Ph.D. in biology or related field and teaching experience required. This career position has the potential for security of employment, subject to UC policy. Salary will be commensurate with credentials. Application review process will start October 15, 2002, but applications will be accepted until position is filled. Candidates should submit a cover letter, curriculum vitae, statement of teaching interests and philosophy, and the names of three references to: Chair, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106. An EO/AA Employer.


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By Gustavo Arellano America's liberal class and MSMers are abuzz right now over Narco Cultura, a documentary about Mexico's horrific drug war and the musical movement that has risen around it. These libs (and more than a few conservatives) are telling each other and the two Mexicans they know about ... More >>
The news waits for no one -- at least that's what we read somewhere -- so it's perfectly understandable that you, the reader, might have missed out on a musical tidbit, breaking news about your favorite venue, or one of our rants. So enjoy this digest-style sampling of some of our biggest stories f ... More >>
See also: Que Se Vende: Impacto Musical Top Selling Albums of the Week Alfredo Ríos, also known as the Mexican corridista El Komander is leaving the AK-47 behind and is bringing his talents to the Celebrity Theatre in Phoenix on Saturday, July 21.
Want to know what new release discs and platters are moving across the Valley at local record stores? We've got you covered with another installment of What's Selling. Corridos and rancheras have a long history of storytelling, dance-inducing beats and violence. Its been 19 years since the ... More >>
Karla Gabriela Lizzaraga-SanchezPhoenix isn't the kidnapping capital of the United States for nothing. We get that wrap because...well...a lot of kidnappings happen in the Valley -- as pointed out in the New Times feature "Seized." Check it out here.A Phoenix teen is the latest victim of this cit ... More >>
America and her husband TerryAmerica Corrales wasn't exactly playing hooky; she was checking up on her restaurant. The full-time teacher and owner of America's Taco Shop decided it was time to pack up her first grade classroom last year and focus on her Downtown taco shop. The buzz that used to b ... More >>
Julio Cesar Chavez is trading his boxing gloves for oven mittens.The 46-year-old Mexican boxing legend plans to open a restaurant in Mesa at Country Club Drive and Southern Avenue as early as May or June, according to an article today in the East Valley Tribune by David Woodfill.We surfed around ti ... More >>
By Michele Laudig
El Break proves there's more to Spanish-language radio than ranchero music
Banda Santa Cruz isn't cheap, but they're worth it
As narcocorridos - Mexican drug ballads - get nastier, the crowds in Phoenix get bigger and bigger
When undocumented workers gather to wait for jobs at the city's first day-labor center, complaints about them should subside. But don't count on it.
La Hacienda
The Valley is now the prime way station for ruthless smugglers engaged in the lucrative trafficking of human cargo -- illegal immigrants
A former madam leads a crusade to rescue prostitutes from a dangerous, addictive lifestyle
Cocaine from Mexico is the currency that drives gangster economics
The bandit Jesus Malverde has been dead for nearly a century. He's still wanted on both sides of the border.
A dying narcotics agent opens his files, and out pours Miguel, just one of a legion of Mexicans who embraced drug-running as their ticket to the American dream
Fife has done much in and to Arizona. We've been keeping track
Drug Enforcement Administration records contain multiple references to a company controlled by a business partner of the Symington family
Business partner of Symingtons gets pass good for one year
U.S. authorities suspect a Mexican vegetable grower with business ties to the Symingtons is involved in drug trafficking
How Governor Symington misused state resources to further the cross-border business interests of his friends and family.
Scott Walker is the longest of long shots to beat boxing legend Julio Cesar Chavez. But the skinny Mesa fighter who calls himself "The Pink Cat" isn't about to miss his golden opportunity.


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Ach Gott und Herr BWV714 [2'08]
Wir Christenleut BWV1090 [2'03]
Jesu, meine Freude BWV1105 [2'19]
The pieces on this disc originate from an extremely exciting discovery from 1985—a manuscript anthology of chorale preludes, compiled by Johann Gottfried Neumeister in the last decade of the 18th century and identified as containing over 30 previously unknown chorale preludes dating from Bach's formative years.
There is tremendous variety and imagination in this collection and these little-known pieces surely deserve to be more widely appreciated, hence this recording as part of Christopher Herrick's complete survey of Bach's organ works for Hyperion. They offer a fascinating insight into the development of the young composer and also give glimpses of the man he was to become.
Other recommended albums
Bach: Organ Miniatures
CDA67211/2 2CDs Archive Service
Bach: Orgelbüchlein
CDA66756 Archive Service
Bach: The Clavierübung Chorales & other great chorales
CDA67213/4 2CDs Archive Service
Bach: The Italian Connection
CDA66813 Archive Service
While most of us dream of winning the lottery it is surely the lifes ambition of every musicologist to discover an unknown manuscript by a major composer. The sense of fulfilment must be all the greater when the discovery fills a glaring gap in our knowledge of the composer in question. An original manuscript source for a Bach organ work, known or unknown, would of course be a rare find indeed, given the paucity of such autograph material, but what Professor Christoph Wolff and Yale music librarian Harold E Samuel found in the John Herrick Jackson Music Library at Yale University was the next best thing. This collection is a vast repository of source materials for the seventeenth and eighteenth centuries and in the course of examining a manuscript anthology of chorale preludes, compiled by Johann Gottfried Neumeister in the last decade of the eighteenth century, they identified over thirty previously unknown chorale preludes dating from Johann Sebastian Bachs formative years. (Given that much of this collection is still to be explored in detail, who knows what other treasures are still to be revealed.) Of course, the attribution of non-autograph works is a speculative business and there are those who prefer not to allow that anything less than perfection could have flowed from Bachs pen, at whatever stage of his development. However, the inclusion of seven pieces known from other sources gave Wolff and Samuel the confidence to make their conclusions known, and to prepare the pieces for publication in 1985.
Neumeister was a teacher and part-time organist, and the emphasis in this collection on relatively simple pieces, most of which can be played without pedals, is presumably a reflection of the modesty of his abilities on the instrument. The manuscript is laid out in much the same way as the Orgelbüchlein that is, a comprehensive series of settings for the Church year. It is open to speculation whether Neumeister was copying from an existing anthology, or whether he made his own selections from various sources, taking his cue from Johann Sebastians work. Whichever, it is interesting to note that 22 of the present chorales were listed but not set in the Orgelbüchlein and they include several which do not appear anywhere else among Bachs chorale-based works. At some point the volume passed into the hands of Christian Heinrich Rinck who had studied with one of Bachs last pupils, J C Kittel; he was a keen collector of Bach memorabilia and did much to keep his tradition alive. In all, seven composers are represented among the collections 82 chorale preludes with by far the most significant contributions coming from two generations of the Bach family. In addition to the 38 chorales by Johann Sebastian there are also 25 by Johann Michael Bach, a first cousin of his father Ambrosius, whose vocal music he was still performing during his time at Leipzig. (Johann Michaels daughter Maria Barbara was Bachs first wife.) The other composers represented are Johann Christoph Bach (another cousin), Zachow, Pachelbel, Erich and Sorge.
The preludes on Herr Christ, der einge Gottes Sohn, BWV601 and Ich ruf zu dir, Herr Jesu Christ, BWV639 (recorded by Christopher Herrick on CDA66756) appear in the Orgelbüchlein and therefore represent the latest and most modern music in the collection. With this in mind, Professor Wolff has been able, with some confidence, to date the other settings to between 1700 and 1708, the period when Bach was beginning to make his way in the world as an organist, startling the congregations at Arnstadt and Mühlhausen with his bold accompaniments to the chorales. It is even possible that some date from the time when he was living and studying with his brother Johann Christoph, himself a pupil of Pachelbel, in Ohrdruf. Also known from other sources are Der Tag der ist so freudenreich, BWV719, and Ach Herr, mich armen Sünder, BWV742. These two works have also been attributed to J C Bach and Böhm respectively. In addition, the canonic setting of Ach Gott und Herr, BWV714, is known without the affecting but seemingly unrelated prelude found in Neumeister, while the first part of Machs mit mir, Gott, nach deiner Güt, BWV957, was published in the Bach Gesellschaft as a keyboard fugue in its own right. The straightforward chorale harmonisation found in the Yale manuscript finally identifies it as a chorale prelude.
The roles of organist and composer in the seventeenth and eighteenth centuries were inextricably linked, the player being expected to introduce the chorales on the organ, usually with an improvised piece which would inspire the congregation to sing with fervour. The preludes in the Neumeister collection are undoubtedly written-out examples of the sort of thing he would have had to improvise, and demonstrate that from an early age Bach had a lively and enquiring mind; he learnt by imitation, taking his examples from a wide variety of sources and very quickly improving on them. Naturally these include his fathers cousin, Johann Michael, and Pachelbel, who was his brothers teacher, but also North German influences such as Buxtehude (the prelude on Herzlich lieb hab ich dich, o Herr, BWV1115, is based directly on the opening motif of Buxtehudes Praeludium in C, BuxWV137). This young composers portfolio demonstrates a rapidly burgeoning talent and ability to improve upon his models (the harmonic command is already well advanced with much rich chromatic writing) as well as a desire to experiment, sometimes combining different chorale types within one prelude, e.g. Aus tiefer Not schrei ich zu dir, BWV1099, and Jesu, meine Freude, BWV1105. One of the finest examples is the prelude on the Christmas hymn Wir Christenleut, BWV1090, which compresses the variety of figuration of a partita into one verse of the chorale. The three sections employ highly differentiated textures: in the first, the accompanying motif bears a close family resemblance to that in the Orgelbüchlein prelude on the same chorale, although in a different metre, while the second introduces the compound time signature of the gigue. In the final section Bach abandons the cantus firmus for a short fugal finale, based on the last line of the chorale, whose dotted rhythms perhaps suggest that he was already familiar with the French repertoire.
Attempts to produce a meaningful classification of organ chorales generally fall down because the distinctions within certain basic types can be rather blurred, and of course this becomes all the more so throughout Bachs creative life, as he expanded the possibilities by grafting on free-standing forms to the chorale. Even in the Neumeister collection we find this multiplicity of design within a basic type, particularly that of the chorale motet. As its name implies, this derives from the vocal motet where the chorale melody appears unadorned in one voice, usually the top, against freely moving accompanying parts. Sometimes the lines of the chorale can be separated by interludes and sometimes not, and when there are interludes these may imitate the forthcoming line of the chorale or may not. In Ach Gott, tu dich erbarmen, BWV1109, Bach presents the melody in very small chunks in order to give as many opportunities as possible for pre-imitation, while in O Lamm Gottes, unschuldig, BWV1095, the lines of the cantus firmus are much longer and the imitative counterpoint of the accompanying lines bears no discernible relationship to it. Sometimes, as in Vater unser im Himmelreich, BWV737, and O Jesu, wie ist dein Gestalt, BWV1094, the degree of imitation varies throughout the piece. There are also several fine examples of chorale fughetta, where just the first line of the chorale is used to furnish a fugue subject. Wir glauben all an einen Gott, BWV1098, is a particularly fine and extended piece, while Christe, der du bist Tag und Licht, BWV1096, combines fughetta and motet in one grand design. One of the most forward-looking preludes is the lively and delightful O Herre Gott, dein göttlich Wort, BWV1110, in effect a two-part invention with chorale cantus firmus, a type he was to bring to fruition in the Clavierübung.
Stephen Westrop © 2000
Other albums in this series
Bach: Trio Sonatas
CDA66390 Archive Service
Bach: Partitas & Canonic Variations
CDA66455 Archive Service Download currently discounted
Bach: Orgelbüchlein
CDA66756 Archive Service
Bach: The Italian Connection
CDA66813 Archive Service
Bach: Wachet auf!
CDA67071/2 2CDs Archive Service Download currently discounted
Bach: Organ Miniatures
CDA67211/2 2CDs Archive Service
Bach: The Clavierübung Chorales & other great chorales
CDA67213/4 2CDs Archive Service
Bach: Attributions
CDA67263 Archive Service Download currently discounted
Bach: Great Fantasias, Preludes & Fugues
CDD22062 2CDs Dyad (2 for the price of 1)
Bach: The Complete Organ Works
CDS44121/36 16CDs Boxed set (at a special price) — Deleted


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The Jacksonville Debate Awards Blog Home Conservatives Beginning to Rethink This Newt Gingrich Thing
From the Pork Barrel: V for Poland
* Poland's opposition party outs itself as being into Alan Moore, knowing the score.
* Researchers discover that low intelligence and conservative values lead to racism and bigotry. Or, to put it another way, Rick Santorum's presidential campaign continues apace.
* Indiana really is doing its best to out-Texas Texas.
* Majority of Americans would vote out the entirety of Congress, replace with 535 of those see-saw-y water-drinking bird things.*
* May not have been actual part of poll.
Tags: Christianity, Conservatives, Education, Guy Fawkes, House of Representatives, Indiana, Intelligent Design, Nerdiness, Poland, Polls, Primaries, Republicans, Rick Santorum, Science & Technology, Senate, The Bible
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The myth of civility in American politics.
Just Win, Baby
Bruce Thornton is a Shillman Journalism Fellow at the Freedom Center, a Research Fellow at Stanford's Hoover Institution, and a Professor of Classics and Humanities at the California State University. He is the author of nine books and numerous essays on classical culture and its influence on Western Civilization. His most recent book, Democracy's Dangers and Discontents (Hoover Institution Press), is now available for purchase.
Top Obama Crony Capitalist Deserts Zuckerberg Immigration Scam
Daniel Greenfield, a Shillman Journalism Fellow at the Freedom Center, is a New York writer focusing on radical Islam. He is completing a book on the international challenges America faces in the 21st century.
The Glass Ceiling Myth
Ben Shapiro is a Senior Shillman Journalism Fellow at the David Horowitz Freedom Center and Editor-in-Chief of TruthRevolt.org. He is the author of the new book "The People vs. Barack Obama: The Criminal Case Against the Obama Administration" (Threshold Editions).


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Everyone loves a good fashion and music collaboration. Lady Gaga and Armani, Lana Del Rey and Mulberry, Kylie Minogue and Dolce & Gabbana are just a few of our favourite artist/ designer hook-ups. So we were very excited to learn this morning that Florence Welch will be working with Frida Giannini of Gucci once again on her upcoming tour of the US and Europe.
Grazia reported last year that the flame-haired singer was working with the brand on her previous tour wardrobe after Giannini's based her Autumn/ Winter 2011 collection on by Florence's signature floaty style. When the leggy songstress' latest tour opens this Friday she'll be wearing Gucci Autumn/ Winter 2012, including this floor-length gothic dress reproduced in a sketch by Giannini.
The designer revealed the inspiration behind the latest costumes: 'Seeing Florence evolve as an artist since her last tour has been truly inspiring, and I was delighted to work with her on this new wardrobe. For her on-stage style, we wanted to create a romantic yet modern aesthetic for Florence to interpret with her dark glamour and dramatic sensuality. I am looking forward to the show as Florence always puts an enchanting energy into every performance.'
It seems this pair have struck up a long-term professional friendship as Flo previously described herself as 'extremely flattered' to be the subject of Giannini's work. We can't wait to see what kind of stage creations the pair comes up with over the next couple of months and we'll be sure to update you here on Grazia Daily. The 'Ceremonials' tour will take place in cities across America and Europe, including Boston, Miami, Dallas, Milan and Dublin, where singer is due to deliver her final performance on December 12.


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Breaking: The White House has Vined! The White House has Vined! It's a predetermined fact that all political entities will eventually seize to every form social media in an effort to "speak to kids". And the White House totally killed the casting for its first Vine.
Say hello to Levar Burton an Bill Nye. It's Mr. freaking Reading Rainbow and Mr. freaking Science Guy! These are our people! Now that's how you speak to the early adopters. Just, you know, leave the Vine muted because they're not saying anything important.
Bill Nye @thescienceguy & @levarburton welcome you to the #WHScienceFair! vine.co/v/bP7JIZtYxrK— The White House (@whitehouse) April 22, 2013


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Halley VI is the British Antarctic Survey's latest research station, able to withstand up to -55ºC. Photo: A. Dubber, British Antarctic Survey
As the IceLab exhibition opens in Glasgow today, the British Council's Vicky Richardson, who commissioned the exhibition, talks to us about new architecture in Antarctica, one of the earth's harshest climates and most international places.
Misty Miller performing 'Next To You' for 'Amped', a video series brought to you by The Crypt Sessions and The Selector radio (British Council).
The Selector, our global weekly radio show for new UK music, has teamed up with The Crypt Sessions to bring you 'Amped', a monthly video series with UK artists.
Vocational skills students compete in the WorldSkills contest (Image credit: Sun Xingwei)
Michael Houlgate of the British Council's Skills for Employability team in China describes how an international skills contest shows young people why improving their vocational skills pays off with better jobs.
Asking a friend to provide feedback can improve your teaching skills
Lizzie Pinard, winner of the TeachingEnglish monthly blog award, writes about how reflecting on one's teaching practice can benefit English language teachers who want to improve their skills, with practical tips on how to go about it.
A still from Alfred Hitchcock's directorial debut, 'The Pleasure Garden' (image credit: BFI)
In the biggest restoration project they have ever undertaken, the British Film Institute, a formal partner of the British Council, has restored nine of Alfred Hitchcock's early silent movies. Made between 1925 and 1929, the films are among the greatest achievements of British silent film. Todd Hitchcock of the American Film Institute Silver Theatre explains their lasting


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Probability Of Getting HIV From Tattoo
Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts
Probabilities of getting HIV from cunninglusHi Ryan,You have mentioned in sevral of your answers that there have been few cases of HIV tranmission from a female to a male through cunninglus, and therefore the probabilities of getting infected is low. I might sound a bit wierd, but when you...
Response from Ryan M. Kull, C.S.W
Columbia University's Health & Related ServicesYou shouldn't worry, but that does not mean that you are at zero risk for infection. Having mucous membrane (like the mouth) exposure to the fluids (blood,semen,vaginal secretions) of a person of unknown risk justifies HIV testing. However,... Read more »
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Canada: HIV, Hepatitis Tests Urged After Unlicensed Tattoo Parlors Closed in CalgaryAfter receiving tips from the public, Calgary health officials shut down seven unlicensed tattoo and piercing parlors during recent investigations. Officials said customers of the establishments listed below should seek testing for hepatitis C and... Read more »
Professor PozPhoto: John Phillips . One of the first things you notice about Francisco Ibáñez-Carrasco, 47, is the multicoloured fish tattoo on his neck. In his early twenties, getting inked was his way of side-stepping a boring, conventional life. "The... Read more »
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