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Quotes & Info
|RIGL > SEC Filings for RIGL > Form 10-Q on 5-Nov-2013
|All Recent SEC Filings
Quarterly Report
This discussion and analysis should be read in conjunction with our financial statements and the accompanying notes included in this report and the audited financial statements and accompanying notes included in our Annual Report on Form 10-K for the year ended December 31, 2012. Operating results for the three and nine months ended September 30, 2013 are not necessarily indicative of results that may occur in future interim periods or for the full fiscal year.
This Quarterly Report on Form 10-Q contains statements indicating expectations about future performance and other forward-looking statements within the meaning of Section 27A of the Securities Act, and Section 21E of the Exchange Act, that involve risks and uncertainties. We usually use words such as "may," "will," "should," "could," "expect," "plan," "anticipate," "believe," "estimate," "predict," "intend," or the negative of these terms or similar expressions to identify these forward-looking statements. These statements appear throughout this Quarterly Report on Form 10-Q and are statements regarding our current expectation, belief or intent, primarily with respect to our operations and related industry developments. Examples of these statements include, but are not limited to, statements regarding the following: our business and scientific strategies; the progress of our and our collaborators' product development programs, including clinical testing, and the timing of results thereof; the potential impact of our cost reduction plans and reduction in workforce, our corporate collaborations and revenues that may be received from our collaborations and the timing of those potential payments; our expectations with respect to regulatory submissions and approvals; our drug discovery technologies; our research and development expenses; protection of our intellectual property; sufficiency of our cash and capital resources and the need for additional capital; and our operations and legal risks. You should not place undue reliance on these forward-looking statements. Our actual results could differ materially from those anticipated in these forward-looking statements for many reasons, including as a result of the risks and uncertainties discussed under the heading "Risk Factors" in Item 1A of Part II of this Quarterly Report on Form 10-Q. Any forward-looking statement speaks only as of the date on which it is made, and we undertake no obligation to update any forward-looking statement to reflect events or circumstances after the date on which the statement is made or to reflect the occurrence of unanticipated events. New factors emerge from time to time, and it is not possible for us to predict which factors will arise. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements.
We are a clinical-stage drug development company that discovers and develops
novel, small-molecule drugs for the treatment of inflammatory and autoimmune
diseases, as well as muscle disorders. Our pioneering research focuses on
intracellular signaling pathways and related targets that are critical to
disease mechanisms. We currently have five product candidates in development:
fostamatinib, an oral SYK inhibitor for ITP that we expect to commence Phase 3 clinical trials; R348, a topical JAK/SYK inhibitor for dry eye in Phase 2 clinical trials; R118, an AMPK activator entering Phase 1 in early 2014; and two oncology product candidates in Phase 1 development with partners BerGenBio AS and Daiichi Sankyo.
Since inception, we have financed our operations primarily through the sale of equity securities, contract payments under our collaboration agreements and equipment financing arrangements. Our research and development activities, including preclinical studies and clinical trials, consume substantial amounts of capital. As of September 30, 2013, we had approximately $230.9 million in cash, cash equivalents and available-for-sale securities. We believe that our existing capital resources will be sufficient to support our current and projected funding requirements through at least the next 12 months. Unless and until we are able to generate a sufficient amount of product, royalty or milestone revenue, we expect to finance future cash needs through public and/or private offerings of equity securities, debt financings or collaboration and licensing arrangements, as well as through interest income earned on the investment of our cash balances and short-term investments. With the exception of contingent and royalty payments that we may receive under our existing collaborations, we do not currently have any commitments for future funding.
Product Development Programs
Our product development portfolio features multiple novel, small-molecule drug candidates whose specialized mechanisms of action are intended to provide therapeutic benefit for a range of inflammatory and autoimmune diseases, as well as muscle disorders.
Clinical Stage Programs
Fostamatinib - Immune Thrombocytopenic Purpura
Disease background. Chronic ITP affects approximately 100,000 people, with the majority of these cases being in women. ITP is a blood disorder in which the immune system attacks and destroys the body's own blood platelets, which have an important role in the clotting and healing process. ITP patients can suffer bruising, bleeding and fatigue as a result of their low blood platelet counts. Currently marketed therapies aim to raise blood platelet counts, but do not address the etiology of the disorder.
Orally-available SYK inhibitor program. Platelet destruction from ITP is mediated by IgG signaling, and fostamatinib is a potent inhibitor of IgG signaling. The results of our Phase 2 study of fostamatinib to evaluate its safety and initial efficacy in chronic ITP patients, published in Blood (volume 113, number 14), showed that fostamatinib may be effective in treating this rare autoimmune disorder. In this clinical trial, fostamatinib was orally administered in varying doses for 30 or more days and demonstrated that it can improve platelet counts in highly refractory patients.
In October 2013, we met with the U.S. Food and Drug Administration (FDA) for an end-of-Phase 2 meeting for fostamatinib in ITP. We expect to initiate two pivotal Phase 3 studies in the first half of 2014. Each of these trials is expected to enroll approximately 75 patients who would be treated for six months and have the option to enroll in an extension study. These trials will be randomized, placebo-controlled and will enroll verified ITP patients with platelet counts below 30,000 platelets per microliter of blood. The goal of the trials will be to achieve a durable platelet count increase to over 50,000 platelets per microliter of blood. We expect top line data from these studies in 2015.
Fostamatinib-Rheumatoid Arthritis
Disease background. RA is a systemic autoimmune inflammatory disease that causes damage to the joints and other organs, affecting approximately 1 in 100 people in the United States. It is a major cause of disability and is also associated with reduced life expectancy, especially if it is not adequately treated.
In September 2013, we announced that we would not continue further development of fostamatinib for the treatment of RA or lymphoma due to insufficient efficacy findings from recent clinical trials and the competitive landscape in those indications.
The (Oral SYK Inhibition in Rheumatoid Arthritis) OSKIRA program was designed to investigate fostamatinib as a potential new oral treatment option for RA and an alternative to injectable therapies for patients with an inadequate response to conventional disease modifying anti-rheumatic drugs (DMARDs). OSKIRA-1 was a 12-month study with approximately 900 patients, examining the effect of fostamatinib compared with placebo over a 24 week period, in patients responding inadequately to MTX. OSKIRA-1 had co-primary endpoints of American College of Rheumatology (ACR)20 scores and mTSS (x-ray endpoint assessing structural progression) at 24 weeks. OSKIRA-2 was a 12-month study with approximately 900 patients, examining the effect of fostamatinib compared with placebo over a 24 week period, in patients responding inadequately to DMARDs. OSKIRA-2 had a primary endpoint of ACR20 at 24 weeks. OSKIRA-3 was a six-month study of approximately 320 patients assessing the effect of fostamatinib compared with placebo in patients responding inadequately to TNF-? antagonist therapy. The primary endpoint of OSKIRA-3 was ACR20 at 24 weeks.
In June 2013, AZ announced the topline results from OSKIRA-2 and OSKIRA-3, two pivotal Phase 3 clinical trials investigating fostamatinib, the first oral SYK inhibitor in development for RA. In the OSKIRA-2 study of patients inadequately responding to DMARDs, fostamatinib in combination with DMARDs showed statistically significant improvements in ACR20 response rates at 24 weeks compared to placebo. In the OSKIRA-3 study of patients inadequately responding to MTX and a single TNF-alpha antagonist, fostamatinib in combination with MTX showed statistically significant improvements in ACR20 response rates at 24 weeks in the 100mg twice daily group but not in the group given 100mg twice daily for four weeks followed by 150mg once daily compared to placebo. The safety and tolerability findings for fostamatinib observed in the OSKIRA Phase 3 program were generally consistent with those previously reported in earlier studies. The most commonly reported adverse events in the OSKIRA program include hypertension, diarrhea, nausea, headache and nasopharyngitis (common cold).
Based on the totality of the results of the OSKIRA Phase 3 program in patients with RA, in June 2013, AZ informed us that it would not proceed with regulatory filings and, instead would return the rights to the compound to us. AZ is solely responsible for all costs and expenses incurred by both parties in connection with the transfer of responsibilities within 180 days from the date of written notice of termination, which was June 7, 2013.
In April 2013, AZ announced top-line results of OSKIRA-1, a Phase 3 study to assess the efficacy and safety of fostamatinib. OSKIRA-1 had two primary endpoints: assessing signs and symptoms of RA as measured by ACR20 response
rates, and an X-ray endpoint known as mTSS (modified Total Sharp Score). In the OSKIRA-1 study, fostamatinib achieved a statistically significant improvement in ACR 20 response rate at 24 weeks compared to placebo. Fostamatinib did not demonstrate a statistically significant difference in mTSS compared to placebo at 24 weeks. The safety and tolerability findings for fostamatinib observed in the OSKIRA-1 study were generally consistent with those previously reported for the TASKi Phase 2 program. The most commonly reported adverse events were typical of those seen in earlier studies, including hypertension, diarrhea, nausea, headache and nasopharyngitis (common cold).
Fostamatinib-Other Indications
In addition to RA, fostamatinib had been studied in patients with other immune disorders and some cancers. AZ commenced Phase 2 clinical trials to investigate the effect of fostamatinib on hematological malignancies in the first quarter of 2012. The randomized double-blind Phase 2 clinical trial was designed to evaluate the effectiveness of two doses of fostamatinib (100mg twice daily and 200mg twice daily) in patients with worsening or unmanageable diffuse large B-cell lymphoma. As discussed above, we have decided not to continue further development of fostamatinib for the treatment of lymphoma.
Disease background. Allergic asthma is a chronic inflammatory disorder of the airways. Asthma affects the lower respiratory tract and is marked by episodic flare-ups, or attacks, that can be life threatening. In some patients, allergens, such as pollen, trigger the production of immunoglobulin E (IgE) antibodies, which then bind to mast cells and cause an intracellular signal that results in the release of various chemical mediators. When this process occurs repeatedly over time, it creates persistent inflammation of the airway passages, resulting in the chronic congestion and airway obstruction associated with allergic rhinitis and asthma, respectively.
Inhaled SYK inhibitor program. R343 is a potent SYK inhibitor that blocks IgE receptor signaling. Mast cells play important roles in both early and late phase allergic reactions, and SYK inhibitors could potentially prevent both phases. Based on its mechanism of action, this inhaled SYK inhibitor may provide a new treatment paradigm for the largest group of patients with allergic asthma whose symptoms range from acute to chronic phases of the disease.
In 2005, we announced a collaborative research and license agreement with Pfizer, Inc. (Pfizer) for the development of inhaled products for the treatment of allergic asthma. The collaboration was focused on our preclinical small-molecule compounds, which inhibit SYK. R343 was the oral SYK inhibitor small molecule at the center of this collaboration. Pfizer completed the Phase 1a clinical trial of an inhaled formulation of R343, which commenced in December 2007 and resulted in a payment of $5.0 million to us. Pfizer also completed an initial Phase 1b allergen challenge clinical trial. In 2011, we assumed development of R343 after Pfizer returned full rights to the R343 program to us as a result of its decision to exit research and development in the allergy and respiratory therapeutic area, and the collaborative research and license agreement was terminated.
SITAR. In August 2013, we announced that R343, an inhaled SYK inhibitor being evaluated as a potential therapeutic for patients with allergic asthma, did not meet the primary or secondary endpoints in a recently completed Phase 2 clinical study. The primary endpoint was the change in pre-bronchodilator FEV1 (a measure of lung function) from baseline to dosing completion at Week 8, comparing active doses to placebo. R343 was shown to be relatively safe and well tolerated at both doses. The Phase 2 clinical study, called SITAR (SYK Inhibition for Treatment of Asthma with R343), was designed to randomize approximately 270 adults with allergic asthma into the three arms of the study for eight weeks of treatment with either of two different doses of the study agent or placebo. R343 is being delivered directly into the lungs via a dry powder inhalation device. In light of these overall findings, we have decided not to move forward with R343.
R333-Discoid Lupus Erythematosus (DLE)
Disease background. DLE is an autoimmune disease of the skin characterized by disc-shaped sores with inflammation, swelling, scaling, scarring, pigment discoloration and hair loss. The lesions most commonly appear in sun exposed areas, predominantly on the face, chest and scalp. This disease has an acute phase, which research has connected to SYK signaling within the immune cascade. There is also a chronic phase of the disease due to the abundance of JAK signaling. Current treatments for DLE have either poor efficacy or significant toxicities.
Topical Dermatological JAK/SYK inhibitor program. R333 is a topical dermatological JAK/SYK inhibitor, which may be useful in treating both the acute and chronic phases of DLE. We completed the Phase 1 clinical study of its topical agent to test its application in treating acute and chronic phases of DLE in the first half of 2012.
SKINDLE. In October 2013, we announced that R333, which was being evaluated as a potential therapeutic for active skin lesions in patients with DLE in a Phase 2 clinical study, called SKINDLE (SYK Kinase Inhibition for DLE), did not meet the primary endpoint in a recently completed Phase 2 clinical study. The primary endpoint was the proportion of
patients who achieved at least a 50% decrease from baseline in the total combined Erythema and Scaling score of all treated lesions at Week 4. R333 was shown to be relatively safe and well tolerated. In light of these overall findings, we have decided not to pursue this indication further with R333.
R348-Keratoconjunctivitis Sicca
Disease background. Chronic dry eye, or keratoconjunctivitis sicca, an inflammatory disease that often affects the lacrimal (tear producing) glands of the eye. Over five million Americans suffer with this disorder, and many patients with chronic dry eye may also suffer with autoimmune conditions, including systemic lupus erythematosus and rheumatoid arthritis. Chronic dry eye is an irritating and painful disease that may be destructive to the cornea if not well controlled.
Topical Ophthalmic JAK/SYK inhibitor program. Since both JAK and SYK are important components in the body's immune and inflammatory responses, R348's combined JAK/SYK inhibition is expected to offer relief directly to the eye. A recently completed Phase 1 study of R348 in patients with dry eye disease showed that the drug candidate is well tolerated. In July 2013, we initiated a Phase 2 study, called DROPS (Dry Eye Rigel Ophthalmic Phase 2 Study). This multi-center, randomized, double-masked study, will evaluate two doses of R348 versus placebo administered twice a day over a three-month period in approximately 210 patients with dry eye disease. The efficacy endpoints will include change from baseline in corneal staining, tear production and dry eye symptom scores. Results of this Phase 2 study are expected in the second half of 2014.
Research/Preclinical Programs
We are conducting proprietary research in the broad disease areas of inflammation/immunology and muscle wasting/muscle endurance. Within each disease area, our researchers are investigating mechanisms of action as well as screening compounds against potential novel targets and optimizing those leads that appear to have the greatest potential.
We have active small molecule discovery programs in muscle wasting. Excessive loss of muscle in the context of illness can contribute significantly to both morbidity and mortality rates. Many conditions that have been associated with muscle atrophy, or the loss of muscle mass, including cancer, chronic heart failure, chronic kidney disease, mechanical ventilation and aging (sarcopenia), have significant patient populations that may benefit from therapeutics that counter such muscle loss.
In the area of muscle atrophy and muscle endurance, we are focusing on several signaling pathways that are important for muscle homeostasis. Patients with chronic illnesses such as chronic heart failure, chronic obstructive pulmonary disease (COPD), or diabetes, often experience a decrease in strength and increase in fatigue due to muscle myopathy. We are conducting preclinical studies of an oral activator of adenosine monophosphate (AMP)-activated protein kinase (AMPK) to examine whether it can improve the body's energy utilization and restore muscle endurance in chronically ill subjects. Our focus for this program is to evaluate its potential treatment in patients with peripheral vascular disease who exhibit exercise intolerance. We expect to enter into the clinic with this program in the beginning of 2014.
Corporate Collaborations
We conduct research and development programs independently and in connection with our corporate collaborators. We currently do not have significant active collaborations.
In February 2010, we entered into an exclusive worldwide license agreement with AZ for the development and commercialization of our oral SYK inhibitors for the treatment of human diseases other than those primarily involving respiratory or pulmonary dysfunction. The agreement included a license of rights to fostamatinib, our late-stage investigational product candidate for the treatment of RA and other indications. AZ was responsible for conducting and funding all future development, regulatory filings, manufacturing and global commercialization of products containing most of our oral SYK inhibitors. The agreement became effective on March 26, 2010, and we received an upfront payment from AZ of $100.0 million in April 2010. In September 2010, we earned $25.0 million from AZ for completing the transfer of the fostamatinib long-term open label extension study to AZ and for the initiation of Phase 3 clinical trials in the fostamatinib program by AZ.
In June 2013, based on the totality of the results of the OSKIRA Phase 3 program in patients with RA, AZ informed us that it would not proceed with regulatory filings and, instead would return the rights to the compound to us. AZ is solely responsible for all costs and expenses incurred by both parties in connection with the transfer of responsibilities up to December 4, 2013.
In September 2013, we announced that we would not continue further development of fostamatinib for the treatment of RA or lymphoma due to insufficient efficacy findings from recent clinical trials and the competitive landscape in those indications.
Other Agreements
We have several active collaborations with additional partners. Under these collaborations, which we enter into in the ordinary course of business, we received or may be entitled to receive upfront cash payments, progress dependent contingent payments and royalties on any net sales of products under the agreements. Total future contingent payments to us under all of these current collaborations could exceed $160.0 million if all potential product candidates achieved all of the payment triggering events under all of our current collaborations (based on a single product candidate under each agreement). Of this amount, up to $68.9 million relates to the achievement of development events, up to $53.6 million relates to the achievement of regulatory events and up to $37.5 million relates to the achievement of commercial or launch events.
Since we do not control the research, development or commercialization of the product candidates generated under these collaborations, we are not able to reasonably estimate when, if at all, any contingent payments may be payable to us. As such, the contingent payments we could receive thereunder involve a substantial degree of risk to achieve and may never be received. Accordingly, we do not expect, and investors should not assume, that we will receive all of the potential contingent payments provided for under these collaborations and it is possible that we may never receive any additional significant contingent payments under these collaborations.
In June 2012, we entered into an exclusive worldwide license agreement with AZ
for the development and commercialization of our program, R256, an inhaled JAK
inhibitor shown to inhibit IL-13 and IL-4 signaling, which is being investigated
as a treatment for moderate to severe chronic asthma. AZ will be responsible for
beginning the first-in-human clinical studies for R256, and for designing and
conducting the clinical development of the compound. AZ will also have exclusive
rights to commercialize R256 around the world. AZ paid us an upfront payment of
$1.0 million in July 2012. Under the agreement, we were obligated to provide the
following deliverables: (i) granting a license of rights to our program, and
(ii) delivery of a small batch of compound to AZ. We concluded that these deliverables should be accounted for as separate units of accounting. As our obligations with respect to the deliverables were achieved by June 30, 2012, we recognized revenue of $1.0 million in the second quarter of 2012.
In June 2011, we entered into an exclusive license agreement with BerGenBio for the development and commercialization of an oncology program. BerGenBio is responsible for all activities it wishes to perform under the license we granted to it. In July 2012, we received a payment of $500,000 from BerGenBio due to us 12 months from June 29, 2011, the effective date of the agreement. We recognized the payment as revenue in the second quarter of 2012.
In August 2002, we entered into a collaboration agreement with Daiichi to pursue research related to a specific target from a novel class of drug targets called ligases that control cancer cell proliferation through protein degradation. In April 2013, we received a $1.4 million payment from Daiichi related to the filing of an investigational new drug (IND) application for an oncology compound. In January 2012, we received a $750,000 payment from Daiichi related to an oncology compound in pre-clinical testing at Daiichi. We have earned, to date, payments under this arrangement totaling $7.9 million and may earn additional payments in connection with the achievement of certain clinical events. The research phase of this three-year collaboration expired in August 2005. Under the terms of the collaboration agreement, we retain the rights to co-develop and co-promote certain products resulting from this collaboration in North America, while Daiichi retains co-development and promotion rights in the remainder of the world. Future events that may trigger payments to us under the Daiichi agreement are based solely on Daiichi's future efforts and achievements of specified events.
Research and Development Expenses
Our research and development expenditures include costs related to preclinical and clinical trials, scientific personnel, supplies, equipment, consultants, sponsored research, stock-based compensation, and allocated facility costs.
We do not track fully-burdened research and development costs separately for each of our drug candidates. We review our research and development expense by focusing on three categories: research, development, and other. Our research team is focused on creating a portfolio of product candidates that can be developed into small-molecule therapeutics in our own proprietary programs or with potential collaborative partners and utilizes our robust discovery engine to rapidly discover and validate new product candidates in our focused range of therapeutic indications. "Research" expenses relate primarily to personnel expenses, lab supplies, fees to third party research consultants and compounds. Our development group leads the implementation of our clinical and regulatory strategies and prioritizes disease indications in which our compounds may be studied in clinical trials. "Development" expenses relate primarily to clinical trials, personnel expenses, lab supplies and fees to third party research consultants. "Other" expenses primarily consist of allocated facilities costs and allocated stock-based compensation expense relating to personnel in research and development groups.
In addition to reviewing the three categories of research and development expense described in the preceding paragraph, we principally consider qualitative factors in making decisions regarding our research and development programs, which include enrollment in clinical trials and the results thereof, the clinical and commercial potential for our drug candidates and competitive dynamics. We also make our research and development decisions in the context of our overall business strategy, which includes the evaluation of potential collaborations for the development of our drug candidates.
The following table presents our total research and development expense by category (in thousands).
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Who we are
Melina Kolb
Website: http://melinakolb.com
Joined on: July 15th, 2009
Melina is a 25-year-old multimedia producer who graduated from the University of Chicago with a bachelor's in anthropology. After college, she taught video to bouncy high school students, then quit her job to travel the globe after receiving her acceptance letter to journalism school. She specialized in interactive storytelling at Medill. She is from North Carolina, home of real barbecue, and is an avid fan of food of all kinds.
Recent Posts by Melina Kolb
- "Enter" -- Shift debuts its music video
- The Moving Diaries
- Trauma leads to roadtrip on this episode of The Detour Year
- Mapping out Marfa
- Former AmeriCorps VISTA member talks on The Detour Year
- College grads settle into small town life in Marfa
- Dreamers: Undocumented young adults face uncertainty
- Introducing The Detour Year podcast series
- Journey to Marfa

subset: commoncrawl


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Famous quotes by Lawrence Bixby:Sort:PopularA - Z
|Each handicap is like a hurdle in a steeplechase, and when you ride up to it, if you throw your heart over, the horse will go along, too.
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Friday, 17 June 2011 00:00
Nassau County Executive Edward P. Mangano announced on June 10 that the RFP Panel formed in 2010 to evaluate public-private bids to manage and operate Long Island (LI) Bus operations beginning in 2012 has made an official selection. A contract, to be negotiated, will need the approval of the County Legislature and the Nassau Interim Finance Authority.
After reviewing proposals submitted by three private transportation operators, the panel, chaired by Nassau County Director of Real Estate Carl Schroeter, selected Veolia Transportation, Inc. Upon receiving the panel's selection, the County Executive forwarded it to the outgoing Chief Executive Officer (CEO) of the Rochester Genesee Regional Transportation Authority Mark Aesch, who was retained to review the panel's selection. Aesch independently confirmed the panel's selection and, Mangano said, will further assist the County in transitioning to a privately managed and operated bus system.
Mr. Aesch, Mangano said, is nationally recognized for turning the Rochester Genesee Regional Transportation Authority from a money-losing, under-performing organization into a public sector leader – that has actually reduced reliance on taxpayer dollars. In the coming days, the County Attorney's Office will negotiate a contract for review by the County Executive. The County Executive will determine whether it will go forward to the Presiding Officer of the County Legislature for appropriate legislative action.
"Because an agreement to continue with the MTA as the operator could not be reached, I will move forward with a public-private partnership in 2012 that maintains bus service without ceding to MTA demands for an additional $26 million from homeowners and employers through the form of higher property taxes," said Mangano. "A public-private partnership to operate Long Island Bus makes sense for taxpayers. The steps we take today will protect riders and ensure bus service continues into the future. Residents will enjoy accountability for their tax dollars as the private sector will run bus service more efficiently and effectively and protect residents from real property tax increases."
The creation of a public-private partnership to operate LI Bus is necessary, Mangano said, as the Metropolitan Transportation Authority (MTA) voted on April 27 to cease all bus service in Nassau County after the end of 2011. In its proposal to provide the County's fixed route transit and paratransit services, Veolia Transportation, Inc. proposed a first year budget of $106 million. Mangano called this a massive reduction from the current Long Island Bus budget of $141 million.
While the MTA has proposed to eliminate 27 fixed routes, Veolia Transportation, Inc. will maintain all routes for 2012. The county executive said it was made clear to Veolia that route eliminations will only be considered as a last resort and only after consultation with the County and required public hearings. It was stated that Veolia will study and analyze the current system to determine where efficiencies may be found to reduce the cost of the system, while maintaining and eventually expanding services and in the long term, anticipated revenues will be reinvested in the system to improve services and technology. Veolia also has stated their willingness to expand the County's paratransit system and find efficiencies to improve service and reduce costs. The company has proposed a management team that consists of Michael H. Setzer serving as CEO of LI Bus. With over 30 years of experience in the transit industry, Mr. Setzer has served as CEO of transit systems in Minneapolis, Cincinnati and St. Louis.
In selecting Veolia Transportation, Inc. to provide the County's fixed route transit and paratransit services, the Panel noted the following regarding Veolia Transportation, Inc:
"Clear understanding of the requirements of the Request For Proposal and successful demonstration to the panel of their ability to operate the County's system;
"Extensive and well-funded organization to support the system, both operationally and financially, even through periods of fiscal uncertainty. Veolia is a large organization and has the ability to absorb revenue shortfalls in the event they occur. In addition, Veolia has the ability to obtain funds to make capital purchases with the expectation that reimbursement will come from state and federal sources;
"Experience in every aspect of operation, including grant management and capital program management;
"Strong proposed management team, which has a great deal of experience in successfully managing systems as large as or larger than the County's system;
"Price proposal, which falls within the range established in the independent cost estimate;
"Detailed response to the panel's request for additional information regarding fixed route service adjustments."
Mangano stated that over the coming weeks, Nassau County will negotiate a contract with Veolia Transportation, Inc. to operate Nassau's bus system. Upon reaching an agreement, the contract will then be forwarded to the Nassau County Legislature for approval.


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November 28, 2014
CHICAGO (AP) -- Family and friends have gathered for the funeral of actor and onetime Chicago police officer Dennis Farina.
A funeral Mass was Tuesday morning at Assumption Catholic Church in downtown Chicago. An American flag was draped over Farina's casket. Burial plans are private. Farina died July 22 in Scottsdale, Ariz., after suffering a blood clot in his lung. He was 69.
Farina was raised in Chicago. He served with the Chicago Police Department for 18 years as an officer and burglary detective. He was on duty during the 1968 Chicago riots. He found his way into acting as he neared his forties and was a veteran of Chicago theater.
Farina was a character actor for three decades, appearing in movies like "Saving Private Ryan" and "Get Shorty."
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text: Daniel wrote: > I don't recall now whether that was about order > names or heraldic titles. In either event, I know > a little about both in France, England, and Scotland, > and I don't know of any orders or heraldic titles > that referred to the arms. Ummm ... how about Lyon King of Arms? Robin of Gilwell / Jay Rudin


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At the March meeting of the Manhasset Rotary Club, two Manhasset residents were presented with the "Student of the Quarter" award in recognition of their high school academic achievements and participation in community service. The meeting was held at Pearl East Restaurant, which set the tone for a lovely ceremony.
Kristina Magas, Saint Mary's High School (SMHS), daughter of Mr. and Mrs. Marjan Magas, was honored for her scholastic standing as the number one student in the Class of 2014, as well as for her dedication and motivation in helping others. Miss Magas, who is of Croatian decent, exemplifies the spirit of acceptance and cultural diversity. To her fellow students she is known as a student, leader, musician and athlete who excels in all aspects of her life.
This Friday, April 26, the Manhasset Secondary School Theatre Department is ecstatic to present its first ever student-directed one-act play. The short comedy, Check, Please! by Jonathan Rand, is co-directed by junior students Bridget Lavin and Sydney Klainberg. Check, Please! is a modern romantic comedy about two people who, in their search for love, embark on a series of disastrous dates that become increasingly zanier as the scenes progress. Featured actors include sophomore Saif Amin and freshmen Kate Brady, Kristina DiCarlo, and Jack Eletto. The production's stage manager is Nicole Rinaldi. The show starts at 7:30 p.m. in the Manhasset Secondary School Black Box Theatre at 200 Memorial Place. Admission is $5 at the door. Please join them and support Manhasset's theatre program!
The Manhasset School District is looking for volunteers to join the Shared Decision Making (SDM) teams for each of the individual elementary schools and for the Manhasset secondary school. SDM was developed to transform school organizations into learning communities, facilitating effective communication amongst its members. The team is comprised of administrators, faculty, support staff, parents and in the case of the secondary school team, students. Members serve for two-year terms. The goal of SDM is to improve student performance. Topics and agendas are established through consensus. Responsibilities of members include mandatory attendance at monthly meetings, communication among the team, the stakeholder group, and the executive SCA, and the ability to dedicate a limited amount of time to the efforts being put forth.
During the week of March 4, Munsey Park School hosted its annual Scholastic Book Fair fundraiser. The book fair committee, led by Co-chairs Kim Haggerty and Dana Malvey, transformed the Munsey Park Library into a busy bookstore for the week. This year's theme, Story Laboratory, featured decorations recreating a science laboratory, including laboratory doors with caution tape and a simulated keypad, in addition to an oversized "book robot" at the book fair entrance. The popular family night event kicked-off the exciting book fair week, and featured a visit from author, David Adler, of the "Cam Jansen" series, who was on-hand to sign books.
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The darkly funny new movie from the Coen Brothers, Inside Llewyn Davis, takes us inside the smoky clubs of the Greenwich Village folk scene. It's 1961, and the sad-eyed Llewyn Davis can't catch a break. Music royalties are non-existent. He's always in search of an empty couch to crash on. His singing partner has jumped off the George Washington Bridge. And he's lost a cat.
NPR's Melissa Block recently spoke with the film's star, Oscar Isaac, about playing the less-than-likable, sometimes grating Davis — a role that required him to to rely less on his own personal charm, and to learn a whole new style of guitar playing. Hear the radio version at the audio link, and read their conversation below.
What did the directors, Joel and Ethan Coen, say to you in explaining how they saw this character of Llewyn Davis?
When I got the audition materials, there was a little sentence at the bottom that said, "He is not Dylan." He's not the poet: He's the workman.
It's interesting because not only is he not Dylan, but he's the guy who plays just before Dylan, in a room where there are studio executives. And he is the one who is not going to get that deal.
I remember they talked about the Ed Sullivan Show, the night that The Beatles were on. The opening act that night that went on to do nothing? That's me.
You do all your own singing and playing guitar in the movie. Have you been playing and singing a long time?
I've been playing guitar and singing, I guess, for about 20 years now. I met this guy as I was preparing for the audition, Eric Franzen, who is also a New York guy, who lives on McDougal Street above the old Gaslight [Café], and is an amazing finger-picker and singer and actor, as well. And I serendipitously just met him randomly before the audition and he started helping me prepare. When he started teaching me the style of playing, he said, "How long you been playing?" I was like, "I've been playing for about 20 years." He goes, "No — you've owned a guitar for 20 years. You've been playing for, like, six months."
This style of playing is called Travis picking, which is a very complicated, syncopated style of playing — much like stride piano or ragtime piano. And it requires the thumb to be the metronome and to carry the bass line, while the fingers independently do the melody.
The music in the film is traditional songs, going way, way back. Were they familiar to you, or did you have to learn them from scratch?
I had to learn them from scratch.
Yeah, I wasn't familiar with any of the songs. I grew up listening to Dylan, but I wasn't aware of these traditional tunes — and also what the folk artist was, especially someone like Dave Van Ronk. In a way, they were [like] a curator, or a DJ. They would find all these old songs and arrange them, and then present them. And they were songs that people would never really get a chance to hear otherwise.
As records became more popular, [there emerged] this idea of "the original": "I've got the original on the recording — what do I need you to sing me a version for?" And then the focus became, "What's new? Can you write me something new?" And Llewyn plays old songs. He doesn't do new songs. So, he's at a crossroads, you know: "What do I do? My authentic voice is to sing old folk songs, and if you guys aren't interested in that, am I supposed to change?" So that's his dilemma. But he's not above hypocrisy, either. When he really needs to, he'll go and record some cheesy pop song to get some dollars to pay for whatever he needs to pay for.
Okay, I've got to ask you about that cheesy pop song, because this is one of the highlights of the movie. You go in for a session. You're with Justin Timberlake and Adam Driver, and you're singing a song called "Please, Mr. Kennedy." It's a novelty song, and the premise is a claustrophobic astronaut who does not want to go to space. We can laugh at this scene now, but which you had to do this with a straight face. You guys in the studio are dead serious.
This was a great piece of direction. He can make fun of it all he wants beforehand, and he says at one point, "I appreciate the gig, but who wrote this?" And unfortunately, it's the guy sitting in front of me, Justin's character. But once he gets into it, he commits. And he starts enjoying the process of singing and recording.
Llewyn Davis does a lot of things wrong. He rubs a lot of people the wrong way, he's caustic, he offends people, he has a bad sense of timing. Was it important to you that he be likeable? How do you find a likeable guy in there?
(Laughing) We never talked about him being likeable.
No, not really. I thought about the comedy of resilience and why it is that sometimes we find someone going through hardship, how that can be funny. I thought about Buster Keaton, that somebody who's constantly going through near-death experiences — and yet we laugh. We root for him at the same time, and yet his face is always just kind of this melancholic gaze, whether he's in love or fighting a bad guy or having a house fall on top of him. So, I tried to attack the character in that way — to not use warmth within traditional means, not express warmth through smiling or charm or even physical contact, to take all those tools away. You have to find other ways.
This guy Gerry Grennell, who I've worked with many times — he's a fantastic acting teacher and dialect coach — he sent me Bluebirdby Charles Bukowski. That was a mantra for me. I believe the first line is, "There's a bluebird in my heart that wants to get out, but I'm too tough for him. So I inhale cigarette smoke and pour whiskey on him, and the whores and the bartenders never know that he's in there." And that's what the music is for Llewyn. That's the only time he shows that little bluebird.


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Search pictures and profiles of Senior Singles near you right now. Discover how online dating sites make finding singles in the United States, Canada, and all over the world simple, safe and fun! Once you browse profiles and pictures start flirting, messaging and connecting with other members of the SeniorPeopleMeet.com community. Search today and find other sexy, intelligent singles for casual dating or a serious relationship in your area.Search Single Senior Men | Search Single Senior Women
A little about me...
I love life! From long walks on the beach, to intimate dinners...Planning is awesome...Spontaneity is sublime!
Life is much richer when you get to share and enjoy new adventures with someone you really care about; A best friend...A partner.
About the one I'm looking for...
Honesty, Integrity, and laughter! I love to laugh! Laughter is the energy to life!
From sports to concerts...must be versatile...I love people...and so must you!
Communication is a must! Lets talk! Oh...and PLEASE...A non-smoker!
I'd just like to add...
You must be an animal lover, as I have a dog that will always be by my side...
I have two adult children that I am very proud of. They have chosen mates whom I love and enjoy .....So now it is my turn!
In my mind I am still "Sporty Spice", but the reality of career choices and raising my children, I am not as active as in my youth. I can still enjoy a game of tennis, kayaking, biking all over, long walks on the beach, dancing til dawn, skiing down a mountain, or just whipping up something to munch on while watching a movie..Its all about enjoying the person you're with.
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Updated: This program presents an original way of the famous Rubik's Cube by an assembly of 27 multi-colored cubies isolated in the space. Even during its deformations, it allows a 3D vision of the cube thanks to the basic MFC graphic functions. This simulation can also rapidly calculate a solution to reordering the Cube.
Latest GDI+ Articles
How to Use a Font Without Installing It
How to use a font without installing it first on user systems.
Progress Sphere
Learn about a class that displays and automates a translucent, shadowed modal dialog with a progress sphere.
File Open and Save As Dialogs for MFC Applications Using GDI+
Learn about CFileDialog-derived classes that offer an easy way to implement File Open and Save As dialogs in MFC applications that use GDI+.
Mould Text in Any Shape
Sometimes, putting text in a rectangular block may just be a little too straight. With the C++ class QEnvelopeText, you can mould a piece of body type in any shape.
Let Your Characters Dance and Wiggle
This versatile class arranges the characters of a text string along any curve.
Latest Developer VideosMore...
Latest CodeGuru Developer Columns
MFC Integration with the Windows Transactional File System (TxF)
The Transactional File System (TxF), which allows access to an NTFS file system to be conducted in a transacted manner through extensions to the Windows SDK API. MFC 10, has been extended to support TxF and related technologies. This support allows existing MFC applications to be easily extended to support kernel transactions.
Webforms to MVC: Handling the User Control Transition
Explore the differences that webforms programmers moving to MVC might encounter in user controls.
Persisting Colors and Other Settings with Visual Basic
Discover two ways that you can use Visual Basic to save colors.
Working with State Machines in the .NET Framework
Arun Karthick introduces you to the state machine model and shows you how to create a simple working state machine sample using the .NET framework in the C# language.


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- North America »
- United States »
- New York »
- Urban Asian Radio
Oops… no streams currently available for Urban Asian Radio.
Click here to visit the Station's website:
Urban Asian Radio Is an Internet Based radio website from New York that plays Asian, Bollywood, Bhangra genre of music.
New York - United States - English
Songs playing in Urban Asian Radio


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Live Sports Centre
Scoreradar's new U.S. Sports Service
Live Match Tracker - Tennis
Scoreradar - driven by facts | Your sports data service provider
Welcome to the official homepage of Scoreradar, the market leading supplier of sports data services to the media industry
Scoreradar is a brand of Sportradar, the world's leading supplier of sports related live data, odds solutions and security services to bookmakers, media companies, sports federations and government agencies.
Scoreradar's live turnkey solutions already provide the widest variety of sports and competitions available in the market, but the list of sports to receive live coverage will continue to grow. Our comprehensive sports offer is enhanced by market leading data feeds and applications that service multiple channels such as web, mobile, TV and print.
This website is intended to provide you with essential information about us and our innovative and competitive sports content solutions. Scoreradar provides the most comprehensive and reliable sports information services to the media industry.


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Think ponytails are just for the gym? Mila Kunis's version made us think again.
THE STYLE A center-parted style pulled into a low, delicately curled pony
WHERE A Vogue/Vera Wang dinner in Los Angeles
WHY WE LOVE IT Mila Kunis's look, created by Tresemmé stylist Mara Roszak, is a romantic and princessy without being one bit prissy. The ponytail's spiral is loosened just so; the single cheek-grazing tendril adds a hint of playfulness.Read MoreLess


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3, 12, 2010
people meet funeral
Fri Dec 3 12:34:15 2010 |
people meet funeralCall Baldauff Family Funeral Home & Crematory in Orange City, FL at 386-775-2101, for professional personal and compassionate service in your time of need
.People's Memorial Funeral Cooperative was started in June of 2007 to provide cremation ... At the annual meeting in April 2007, the membership voted unanimously to proceed with ...Meet The Funeral Director. Wed 5 Jan 2pm–5pm. People's History Museum, .
. Bruce Wills - Funeral Director ...All people can create memorial or funeral services that are meaningful events.
..A loved one has died. It's time for the funeral, a place to share our sorrow and say good-bye to the precious soul.You don't have a right to interrupt someone's private funeral. ... people meeting for a military funeral or memorial service or a military funeral ..


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See by Chloé
Grey Alix Leather Shoulder Bag
$107.25 Was $536.25 (80% off)
Product Code: 962144
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- Invest in a soft grey hue to effortlessly compliment this season's eye-catchingly bright neons and pretty pastels with panache. The roomy design of this classic shoulder bag ensures that this will remain a firm favourite for years to come. Treat yourself now, you can never have enough bags in your collection!
- Taupe grainy leather tote featuring a leather shoulder strap, zip top closure with a long buckled tassle to zip pull, two leather top handles and a designer badge to front. See By Chloé shoulder bag is fully lined and has an interior zipped pocket and two slip pockets. Bag measures 27cm x 34cm x 12cm.
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Female Atlantic lobster stuffed with eggs found near Bowen Island
West Vancouver resident Blair Calkins was prawn fishing on the weekend during an...
Latest News
My Second Life brings virtual world alive on TV
Show creator visits Vancouver International Film Centre for VidFest Monday
Marke Andrews, Vancouver SunPublished: Saturday, September 22, 2007
When HBO won a bidding war early this month to telecast My Second Life, it marked a media breakthrough -- a television network buying an online property that was completely created in a virtual world.
It's entirely likely that the deal is the tip of an iceberg, as virtual entities become hot properties.
"This really presents the possibility of a new paradigm emerging, one where people can use virtual worlds to create content," says Douglas Gayeton, the filmmaker who created My Second Life, also titled Molotov's Dispatches, in a telephone interview. Gayeton will appear at VidFest Monday at 11:40 a.m. at the Vancouver International Film Centre.
A scene from the Web series Molotov's Dispatches, recently purchased by HBO for broadcast.
For the past six months, broadcasters have been promoting their shows by leaking clips of them to YouTube. So maybe it makes sense that they cross over and broadcast Web entities.
The genesis of My Second Life is as fascinating as the series itself. Gayeton, a San Francisco filmmaker well versed in new media forms, had been asked by Submarine, a Dutch production company, to make a series of experimental documentaries. Gayeton wanted to make short, episodic documentaries that could be shown on the Web. Before signing on, he had created an avatar -- his online persona -- and spent six months within the virtual social-interactive world Second Life, where he encountered the video diary of an avatar named Molotov Alva.
Gayeton decided to move around Second Life as Molotov, filming his encounters in the virtual world. Once My Second Life was shot, someone at Submarine posted footage on YouTube and, within 72 hours, it was the most-watched film on the video website.
MTV, which hired Gayeton to consult on their virtual world projects, engaged in a bidding war with HBO and the Sundance Channel to acquire My Second Life. Gayeton went with HBO, which will screen the first episode at film festivals this fall and winter and broadcast all seven episodes in the spring. It will also screen the first 35-minute episode next week in Los Angeles to qualify the film for Academy Award consideration in the short subject category.
Gayeton let the creators of the avatars know that their characters were being filmed for his project, which he insists is a documentary despite the animated, fictional element. He wouldn't show them videotapes, but showed them transcripts to make sure the interactions were accurate. This poses a number of questions: How do you draw the line between fiction and documentary? What about privacy issues? And who owns intellectual property of entities that exist in social networks like Second Life?
"Documentaries are, by definition, windows into worlds that you would otherwise be denied access to," says Gayeton. "The idea of objectivity in a documentary it a fallacy. Everything is subjective."
People who appear in live-action documentaries surrender their privacy to the filmmaker, so certainly their online characters can do the same. But what about these characters being the intellectual property of their creators?
"The issue of intellectual property and how that extends into the virtual world is something we haven't begun to know how to frame the question about yet," says Gayeton. "I think what will emerge will be a series of new ways of looking at how social networks and virtual worlds work, and I don't think we're close to that yet."


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Mr. Ravi Rishi, Chairman, Vectra Group
Dear Friends,
2011 was a tumultuous year globally, but the Vectra Group was able to exploit a number of strategic opportunities successfully, which led to the Group expanding: Vectra acquired an oil field in Georgia, built industrial sheds in Greater Noida and launched Cosmos Aviation in Sri Lanka. 2012, however, will be a year for consolidation, cost rationalization and focus on the bottom line, across all the Group companies, not just over the year or the month but week by week. This will require the contribution of every member of the Vectra family.
The Vectra Group, amongst the core objectives for this year, aims to increase production of their oil field from 20 barrels to 200 barrels of oil per day, and also increase the helicopter fleet to service the anticipated demand in the Indian market.
I would like to thank all the Vectors for their continued valuable contribution and wish you and your families Happy New Year.
Best Wishes
Ravi Rishi


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Ronald Young will spend Thanksgiving at Aupi Ramdat`s house.
It`s not a family tradition. It`s a financial transaction. And Broward County government is the intermediary.
Ramdat operates a Plantation boarding house that takes in people such as Young for $10 a night, money that comes from a three-month-old county program to help the homeless.


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Posted Thursday, January 17, 2013 --- 6:50 p.m.
Mass shootings can happen anywhere at anytime.
That's why staff at St.Mary's Hospital in Madison took some time Thursday morning to prepare for the unthinkable. We want to stress that the following story you are about to see is only a drill.
St. Mary's along with the Madison Police department and other law enforcement staged an active-shooter simulation.
"Over the past several years, you've seen more and more police departments and other first responder agencies practice for active shooters and mass causalities," said Madison Police officer Ed Marshall.
"We have a lot of other lives to look out for other than our own,"
Stehpanie Lehmann has been preparing this drill for more than a year.
"It's horrible we have to plan this way, but in an event that it would happen, I would much rather have all my staff and my co-workers prepared and know how to respond than not,"
"It's sad and scary and it could happen anywhere, when we were planning for this drill it happened in Connecticut," said Beth Risler with the Madison Fire Department.
About 40 staff members participated playing the parts of patients, victims and nurses.
"They are glad we are preparing them, they wanna be ready in case something happens," said Lehmann
"We believe in collaboration and communication,"
John Watts works for a hospital in North Carolina. A situation like this actually happened at his workplace last year.
"A gentleman pulled the gun and a police officer happened to be in the emergency department in that waiting room and he was shot by the police officer," said John.
"And when it really happens, it really opens to your eyes to what the issues can be and what you have to plan for," he added.
They made this simulation as life-like as possible with the bad guys yelling, patients screaming and even fake gunshot wounds.
"There's a lot of panic, there is a lot of elevated emotions in a real event and that's what our goal is to make people's heart's start pounding and really start thinking about what they would do because in a real-life scenario, people tend to freeze and they don't know how to respond," said Lehmann.
Authorities and staff members performed at their best...
"I think things went pretty well," said Marshall after the drill concluded.
In preparation for the worst.
The Sun Prairie and Milwaukee Police Departments also participated in Thursday's drill.


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Friday, 22 October 2010 00:00
What factors contribute to the value of your home? A lot has been said about property values declining because we are closing schools. How can you quantify that? Outside of the number of bedrooms and quality of the home construction, let's examine some of the main factors in attracting prospective buyers:
• Low real estate taxes
• Quality of the school district
• Breadth and depth of programs
• Innovative and progressive planning for the future
• Neighborhoods, ease of commute.
I do not discredit the proximity of your home to a particular school, but in general, prospective buyers are buying a school district. The quality of the entire district is the ultimate selling point.
So let's look at Mineola:
• The school district has one of the lowest tax rates in Nassau County. Much of that can be attributed to our large commercial tax base. The reconfiguration plan seeks to stabilize the tax levy at or near 2.5 percent for a five-year period.
• We are closing schools to preserve programs. It is our full intention to continue to offer the programs we currently do AND enhance student learning with innovative programs. A good example of that is our iPad initiative. We are the first school district to implement a widespread distribution of interactive technology. Other districts have already inquired how they can replicate it. It is these types of programs that will attract parents to Mineola. The same holds true for our implementation of NWEA, which will directly help individual student achievement.
• Neighborhoods will remain essentially unchanged. If we rent a facility it will be to a school. We will retain the use of the fields and playgrounds for residents. The vacant schools will be used when your children are in school, and they will be available to your children when they come home from school.
The current bond proposal delivers the most streamlined cost effective school district possible. It seeks to stabilize tax levies in the worst economy in decades. More importantly it preserves our current educational program and allows us to initiate new innovative programs for children. Please remember that all of our neighboring school districts will struggle with the same financial issues that we have and they will have fewer options to deal with it. I believe all of these factors will make Mineola a very attractive community for prospective buyers.


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Before the Rodarte show in
The first subject of debate was the late Alexander McQueen, whose memorial retrospective exhibition Ms Wintour is involved in organising. It will take place at the Metropolitan Museum of Art in
Thinking about who among the current generation of designers coming up most resembles the designers John Galliano or Alexander McQueen, Wintour's money is on the Rodarte sisters, who have 'Imagination and originality to be in the same spirit as a John [Galliano] or an Alexander.' Wow, we wonder how many times Kate and Laura Mulleavy have watched that clip while dancing round the room?
Finally, thoughts turn to London Fashion Week, (starting tomorrow peeps!) and its anticipated highlights. Christopher Kane and Erdem both earn a namecheck, while totally unprompted, she praises 'the young woman on the street' for the 'individuality and wit' of her dress sense. Amazing. Although Anna Wintour has been present for the last two or three seasons at London Fashion Week, we personally have never seen her anywhere apart from inside the show space.
Of course, now we know that she'll be on the lookout (presumably through her car window) we will make a special effort with our wittiest ensembles, while walking slowly round WC1 and lingering at the traffic lights!


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Pasadena man arrested in connection with arson fires
Published On: Nov 27 2012 07:56:49 AM CST
Pasadena police arrested a man on suspicion of setting several fires in the Pasadena area.
Williams Caruthers was arrested on arson charges. Investigators said he was captured on surveillance video in one of the cases which helped them connect him to a number of fires.
He faces two charges of arson.
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.blog comments powered by Disqus


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African Elephant
Where in the Safari Park: Elephant Valley
If you would like to see elephants, you can travel to Africa, of course, but the easiest way to observe these mighty creatures is to come to the Safari Park! We have two large exhibit yards for our African elephant herd. The adults were rescued from Swaziland in 2003, where they were scheduled to be killed due to overpopulation in that area. Since then, we've celebrated the births of several new additions!
Elephants enjoy a dip in a pool of water, or at least they like to get their feet wet. The large pond, shaded with trees, is for our elephants to do just that, and you can observe the action from the Elephant Viewing Patio, located at the south end of Elephant Valley. There are also shade structures made of simulated rock and plenty of room to roam. Our youngsters are especially fun to watch as they splash about or cavort in one of the mud holes. In fact, the little calves seem to entertain guests no matter what they're up to!
When not at the Park, be sure to watch our elephants live on Elephant Cam.
Cheetah Run
Where in the Safari Park: Lion Camp
Daily at 3:30 p.m., weather permitting.
Witness the fastest land mammal up close and personal doing what it does best: run! Shiley's Cheetah Run, located near Lion Camp and Balloon Safari, is a unique, jaw-dropping experience. During Cheetah Run, the spotted sprinter races on a straight 330-foot-long track that allows the cheetah to really stretch its legs and reach an astounding speed: 0 to 70 miles per hour in just 4 seconds while chasing a mechanical lure attached to its favorite toy. If you're close enough, you may feel the wind as the cheetah passes by!
Ring-tailed Lemurs
Where in the Safari Park: Lemur Walk
Lemurs are native to Madagascar, an island off the southeast coast of Africa. There are numerous species of lemurs, with ring-tailed lemurs among the most populous and easily recognized with their long nose, big eyes, woolly fur, and long, black-and-white-ringed tail. Ring-tailed lemurs are mostly active during the day; unlike other lemurs, they spend more time on the ground than in trees. They are omnivores, eating primarily fruits, leaves, flowers, herbs, bark, and sap.
Want to get up close and personal with lemurs? Vist our brand-new exhibit, Lemur Walk, in Gorilla Forest at the Safari Park! Lemur Walk is an immersive experience, where guests walk on a pathway through the animals' habitat and watch the endearing primates socializing, grooming, jumping, climbing, and even sunbathing, one of the lemur's favorite pastimes.
Lemur Walk is open daily to guests five years of age and older and is located in the renovated former gibbon exhibit. For the comfort of the animals, Lemur Walk attendants remind guests not to touch or feed the animals, as tempting as it may be. Lemur Walk is made possible by a gift from the estate of Burdell C. and Erma K. Bulgrin.


text: > Adamantius wrote: > Generally speaking, they're similar. It can become confusing when > either term is borrowed from one language into another, or when a > translator decides for whatever reason to use one term or the other. > Right oh, the Spanish translation of obleys today would be "barquillos" in my book. People are surprised at that as they are round when I tell them that. I explain, no they are no more than rolled "obleas". They reply ok like if say so. . . but then I have never met a Spanish authority in cookery. > . . .sometimes obleys/oubleys refers to a > form of offertory or sacrificial cake (I think this is from a Greek > word denoting exactly such a cake), that could be offered to a god on > an altar (presumably burnt) or to the god's priests to eat. Ok sounds logical does anyone happen to have the Greek around my little Websters does not even have the word? Nor can I find the etymology for it online. > obley also refers to the Christian communion bread, which is also > often, but not always, a wafer.. .I'm not certain that obleys are > always cooked between two irons, while wafers pretty much are I was waiting for you to answer that one cause I read your article on internet! I found another definition which says obleys "are a type of wafer" because it goes on to say they can be baked instead of cooked in irons. Nola bakes his. Sent Sovi does not explain it just includes them in a couple of recipes calling for them. Assuming that is a more precise way to explain this item I am researching wafers as best I can. Now I can't find details on the English waferys but good castles and palaces had them in the Middle Ages had them which consisted of a department of wafers as staff and a room apart from the kitchen. I think it was in Westiminster Palace where the wafery was on the other side of the hall from the kitchen. Would that indicate that there was no chimney there so irons had to be used? How English were waffers cooked? We certainly have so many tons of wafers in Westminster and on the London streets in Edward IV's time that they are supposed to be the blame of Edward IV's weight gain during his second term as king. Suey


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Oh how sweet. Thank you.
I really love doing the live video chats. It's hard for people to get your tone when you are writing. The live me doesn't sound as hard.
If you haven't viewed the chats and can, please do. Would love more feedback. I'm hoping one day we will be able to have people send in video questions that I'll use.


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Jackpot Duals Recap
Updated: 01/09/2013 - Highlights and a list of winners from Wednesday's Jackpot Duals.
Updated: 01/09/2013 - Highlights and a list of winners from Wednesday's Jackpot Duals.
Updated: 01/08/2013 - The Central Warriors downed the Palisde Bulldogs 54-52 Tuesday night.
Updated: 12/23/2012 - Sixteen football players from the Western Slope make the cut.
Updated: 12/22/2012 - The boys basketball team at Central finished out 2012 with a third straight win.
Updated: 12/21/2012 - Full coverage of the final Friday night session of prep basketball in the year 2012 is all right here.
Updated: 12/20/2012 - GJHS girls lost for the first time this season on Thursday.
Updated: 12/08/2012 - Girls Varsity Wildcat Invite, day three highlights.
Updated: 12/07/2012 - Week 2 of the Overtime features matchups from the varsity girls Wildcat Invite, CMU Mavs, and more
Updated: 12/06/2012 - Scores and hi-lites from Day 1 of the Wildcat Invitational.
Updated: 12/05/2012 - The Sideline Showcase is all about prep boys' basketball.
Updated: 12/04/2012 - Mary Doane has the Central Warriors focusing on the concept of teamwork this winter.
Updated: 12/03/2012 - The Central Warriors already have more wins after three games than they did all of last season.
Updated: 12/03/2012 - There are only three seniors and four juniors on the Central Warriors' wrestling team.
Posted: 11/30/2012 - Day two of the Warrior Challenge comes to an end, and we've got the highlights, results, and post-game.
Updated: 11/29/2012 - We have highlights and results from the opening day of the 2012 Warrior Challenge.
Updated: 11/28/2012 - Grand Junction Rockies to host inaugural Western Slope Baseball Camp in January of 2013.
Updated: 11/26/2012 - Colorado Mesa baseball released their list of signed players for the 2014 season on Monday
Updated: 11/15/2012 - Fruita Monument's Bob Richardson was recognized by the Southwestern League as Co-Coach of the Year
Updated: 11/16/2012 - The Grand Junction Griffins Rugby club is hosting a youth rugby clinic on Saturday at Stocker Stadium.
Updated: 11/13/2012 - KKCO 11 Sports learned early Tuesday evening that Vern McGee is stepping down as head coach of the Central Warriors football team.
Updated: 11/13/2012 - The Montrose Indians took two of the top three honors in SWL for the 2012 football season.
Updated: 11/13/2012 - The Fruita Monument Wildcats swept the top SWL honors for boys' soccer for the 2012 season.
Updated: 11/02/2012 - The Friday Night Football Blitz has all the prep football scores around the Western Slope
Posted: 10/30/2012 - Fruita Monument's Mallory Paulson received the title of the SWL's Most Valuable Player on Tuesday.
Updated: 10/27/2012 - The Friday Night Football Blitz has all your football scores from Friday night.


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St. Joseph County, Ind. The infamous "Internet Casanova" today received two years behind bars for stealing from a female acquaintance.
Raymond Holycross was sentenced Tuesday on a felony theft count out of Kokomo.
Holycross was convicted in Howard County earlier this month of stealing a gun from a female acquaintance there.
In May, in St. Joseph County, Holycross was sentenced to 18 months behind bars for stealing and pawning the camera of a Mishawaka woman.
It's alleged that Holycross used the internet to meet, and steal from numerous women.


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November 28, 2014
KNOXVILLE, Tenn. (WVLT) -- With Spring just around the corner, many homeowners are already thinking about summertime projects - and the Home Depot wants to be ready. On Wednesday, the home improvement superstore announced it would hire more than 400 people for the Spring season.
The company said it has started accepting applications for the upcoming season. Prospective candidates can even apply online at http://careers.homedept.com. Once there, select "In-Store Hourly" in Knoxville and click "Search."
Returning members of the military and veterans looking for work can now take advantage of Home Depot's new Online Military Skills Translator. The system helps match skills gained in the military with positions at Home Depot. The translator and a calendar of military hiring events can be found at http://careers.homedept.com/military
The company also notes that while the jobs are seasonal, many of them do become permanent. In fact, the company pointed out, about half of its seasonal workers last year accepted regular roles with Home Depot.
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Breast Cancer Information Presented by Miami Valley Hospital
Dayton, OH September 30, 2009 – The facts are alarming. A woman's chance of developing breast cancer increases with age. At 20, it's 1 in 1,847. By age 40, it's 1 in 40. The lifetime risk of getting breast cancer is 1 in 8. Learn what you can do to lower you risks or developing breast cancer and get other information about breast cancer myths at the next Mall Walkers Club health event set for Friday, October 9 at the Mall at Fairfield Commons in Beavercreek. Featured speaker is Amy McKenna. McKenna is a registered nurse and a breast cancer coordinator at Miami Valley Hospital. The free event begins at 8:45 a.m. in the food court and healthy snacks will be served.
Miami Valley Hospital offers a health program at Fairfield Commons the second Friday of each month along with free health screenings as part of its Mall Walkers Club. This month blood pressure and cholesterol screenings will be offered.
You do not need to be a member of the club to attend the health talks, but if you would like to join you can do so. Membership is free and is open to anyone 18 or older. Register online at www.mvh.org/mallwalkers or stop by the information desk at Fairfield Commons. When you sign up you will receive a membership bag filled with a pedometer, walking journal and a mall shopping pass.
The Mall at Fairfield Commons is open to walkers Monday through Saturday from
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Jacque Vaughn is notoriously tight-lipped about his starting lineup. When asked whether Maurice Harkless would make his second start a few weeks ago, Vaughn reacted with shock and surprise. Joking that he had not turned his lineup in. The answer was pretty obvious and Harkless has started since.
Now that the Magic continue to struggle at the beginning of the first quarters, the simple answer would be to make a change. To shift the lineup some. Maybe put J.J. Redick in there to get the team going.
After all, according to Basketball-Reference, Orlando's most used lineup was the starting lineup with Redick instead of Harkless. The comparison is pretty astonishing in making that one switch.
The lineup with Redick in it is +9.5 points per 100 possessions. According to 82games.com (stats through Dec. 9), this lineup scores 1.14 points per possession and gives up 0.98 poionts per possession. The lineup with Harkless is -21.9 points per 100 possession and 82games.com reveals it was scoring 0.87 points per possession and giving up 1.00 points per possession through Dec. 9.
The decision to switch the lineup that way seems like a simple one. Vaughn though has no plans of changing the starting lineup it would appear for tonight. But Vaughn is usually pretty tight-lipped about his lineup. Misdirection may always be at work.
Vaughn though is not willing to make a change to make a change. Particularly considering moving Redick off the bench could kill the second unit and their production in erasing some of those holes the Magic have put themselves in.
"The best thing is we will let this game kind of subside and think smartly and watch the film and continue to diagnose what some of the problems may be," Jacque Vaughn said following Wednesday's loss to Atlanta. "Never rush, but be patient and come to a conclusion."
Patience is something the Magic might have some as they look to develop young players like Harkless and Nikola Vucevic who have had their ups and downs in the starting lineup. Harkless particularly has struggled, scoring only 12 points in his last six games and shooting 23.5 percent (4 for 17) field goals.
Something has to change though. Patience seemingly can only last so long when the team is struggling. And Orlando's starts have been extremely frustrating.
The Magic are averaging just 18.5 points per first quarter in the last eight games. They have won just one first quarter in that stretch — ironically against tonight's opponent Golden State. Orlando is giving up 25.0 points per first quarter in that stretch. Undoubtedly, the Magic are struggling to start and it is digging them a big hole.
"I don't know about [changing the guys that start]," Arron Afflalo said. "The guys that are starting the game need to change the way they play. Which includes myself. I'm not alienating anybody. That's for all five of us. The way we start the game has to be with a lot more energy.
"One of us next game will take it upon ourselves to make sure that happens. You can't predict the score or predict making shots so it's hard to say we're going to make shots in the first quarter. Next game, we will play with more focus and passion in the first quarter."
The frustrating part is that the Magic have rarely been blown out and have had a chance to win every single game during this recent stretch. Orlando dug themselves such a deep hole that it took an extreme effort to get back. That might explain some of the slow finishes in Utah and Sacramento when the team had to scramble so much to stay in it.
The effects of who starts and how they perform is felt throughout the game.
"Not even just scoring. It's energy," J.J. Redick said. "It's exhausting at time to try and lift up the energy level sometimes. It's exhausting."
Indeed it is exhausting. The Magic can compete. But the added energy can drain the team. Again, the small margin for error for the Magic means they need a good start so they can dictate the game a bit more.


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mattowesamy - 16 August, 2010
Never the same againI lived in the Ohio Stadium Dorms at the time so for days before the show (my 1st U2) I watched as stage pieces were assembled in my backyard. The show took place on my birthday. It just doesn't get any better than that. I had nosebleed seats but I've been addicted ever since. You can't tell me that Bono didn't sing for me alone that night. I never feel more at peace with the world at large than when I'm with those four wonderful souls. It's like the best church ever.


text: Jd Archive BE A REAL FAN!!! Posted in Cowboys Posts by contributing I am currently commuting back and forth between Abilene and Dallas. Typically I'm only in Dallas on the weekends to spend time with my son. He's 15 and a real rock star on his baseball team. Yet he's Read More


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Posts by daveje
15 posts • joined 20 Feb 2012
Climate shocker: Carry on as we are until 2050, planet will be FINE
It's only a model
I thought El Reg didn't like computer models of climate? Unless they produce results they actually like....
Anyway, I think the biggest issue with the paper is that they have inadequate data for the ocean heat component. A large amount of heat is going into the oceans, but we can't quantify that very well, so I think it's premature to make any great claims based on this paper, since there's obviously a large heat component that's simply missing from their analysis. It's likely that their estimate for sensitivity is an underestimate.
Global warming still stalled since 1998, WMO Doha figures show
Can we get a 'oh no, not again' image?
The usual Lewis cherry-picking has omitted Stott's quote: "the first decade of the 21st century was the warmest on record".
And not one but two references to 1998, which is quite impressive in such a short piece.
Here's a suggestion for a new Register catchphrase: "Statistics? We've heard of it."
SECRET 28 'scientific experts' who Greened the BBC - Revealed!
Re: Impartiality about what?
"17 years and counting of no warming..."
Oh please, the last decade was warmer than the previous one, which was warmer than the decade before that. If you look at the instrumental record, the last 11 years have all been in the 12 warmest years. 17 years ago was what, 1995? Ever year but one since then was warmer. 2010 was a La Nina year, and it's the second warmest year on record! You can repeat denialist memes all you want, but they're not true, and the planet is going about its business regardless.
You can't be convinced, it's just the adult equivalent of putting your hands over your ears and going, "la la la, I'm not listening." Carbon isotope ratios in the atmosphere indicating that fossil fuel emissions cause the recent CO2 increases? The anomalous rises in CH4 and CO2 over the past few thousands years being completely different to the trends in the other interglacials? The complete lack of natural climate drivers? Solar emissions in the wrong direction? The collapse in Arctic ice? Shifting biomes? The planet's energy balance? Basic thermodynamics?
Credit where credit's due. Even though the motivation is pretty clear...
Re: Impartiality and scientific theories
Judging by the number of times Nigel Lawson appears on Newsnight whenever climate change gets in the news, it's abundantly clear that the minority view is quite well represented on the Beeb.
But why anyone thinks Lawson - with no scientific qualifications or training whatsoever - is worth listening to on this subject, is utterly beyond me. The fact that the prominent opponents of AGW in our media are invariably economists, politicians or Delingpoles - but not scientists - should indicate something of the quality of this minority view.
Being someone who constantly criticises Orlowski and Lewis's climate change articles on here as being misleading, poor quality and ideologically driven, I have to say that this is pretty good journalism (for a change), and poor form on the part of the Beeb. The question of whether AGW is happening is a scientific judgement, and there are far too many advocacy groups and non-scientific specialists on that list. And looking at the composition of the attendees, there's not even the illusion of a debate being held - it's a very one-sided list.
That being said, the Beeb came to the right conclusion. The wealth of evidence is such that there is no good reason to give the opponents of AGW equal time or equal weight, particularly when so much of the opposition has been organised by people specialised in the art of creating doubt. People like Fred Singer constantly exploit the wish of journalists to appear impartial by misrepresenting the state of the science, and claiming scientific differences where the fundamentals are in wide agreement. This isn't about abandoning impartiality, it's about making the best judgement based on the available evidence.
So, kudos to Orlowski and the Reg for this, it's a good piece.
Swedish boffins: An ICE AGE is coming, only CO2 can save us
Don't you ever read these papers before posting articles? The paper doesn't claim that peatlands are spreading, only what the potential area might be in Sweden in the absence of human activity. This is in the very first paragraph of the summary, which is the first thing in the paper.
There's a highly speculative claim later in the paper where they consider the idealised maximum extent of global peatlands, and come up with values for carbon sequestration and impacts on radiative warming, but the numbers seem highly unrealistic. That's the only place where the paper discusses the impact on climate - the paper does *not* claim that we're currently being pushed into an ice age.
In the real world, peatlands are decreasing, mainly due to human drainage and clearance activities, with consequent massive release of carbon into the atmosphere. That is quite a different story from that presented in the Reg's article, but that's only to be expected, of course.
1930s photos show Greenland glaciers retreating faster than today
Greenland glaciers not set to cause disastrous sea level rises - study
Himalayan glaciers actually GAINING ice, space scans show
Some things never change, and the lack of critical thinking exhibited by Lewis Page in his typically breathless anti-science reporting is one of them.
The Himalayas are around 1million km2. According to Lewis, the area surveyed in the article is only 5,615 km2, which by my reckoning is around half of one percent. So much for Lewis's "vast region"...
Climate scientist admits lying to obtain 'Denialgate' docs
Re: @daveje, Re: 9 of the 10 warmest years...
Got a source for that?
Re: Re: Re: Re: Re: Re: Re: Re: Balance?
1. The natural factors that determine climate have been going in the opposite direction.
2. Paused? 9 of the 10 warmest years on record have been in the last 10 years. The trend is actually higher now than it was ten years ago.
There's no other way to explain the current warming other than CO2. CO2 is both necessary, ie, you can't explain it without it, and sufficient, ie, CO2 all by itself explains the warming.
If you want to explain the current warming without CO2, then you need to do two things. First, find an explanation which actually works - no one has done that yet. Secondly, your explanation needs to be so strong that it overwhelms the known impact of CO2 as a greenhouse gas. That hasn't happened either.
Re: Re: Re: Re: Re: Re: Balance?
I assume you don't understand how dishonest the question was in the first place.
The question was devised by Lubos Motl, a string theorist who also happens to be a pretty vocal climate denier. It was a very specific question, asking about warming from a particular date, and also asking about statistical significance. The fact was that, at the time the question was asked, 1995 was the furthest you could go back and have the warming not be statistically significant. If the start date was 1994, it was. If the question was asked a year later, the warming was also statistically significant.
In short, it was a trick question. Motl already knew the answer, and deliberately crafted the question to get that answer. The whole point was either to catch Phil Jones out as a dishonest scientist (and to Jones's credit, he answered the question completely honestly), or to make a statement that would be read by gullible deniers as some kind of confirmation that global warming wasn't happening.
It's just another example of the typical sleazy and underhand behaviour that climate deniers get up to.
Climate models need revising: Droughts, heat waves not such a big deal
Typical Register
The headline giveth, but the article taketh away. The paper isn't really about climate models, but about ecology.
The Register's obvious anti-science bias on this subject is bad enough, but I would have hoped the Reg's correspondents would have mastered basic reading and comprehension skills. Or is it really just about the page hits?
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Wow! We've been waiting to see how Victoria Beckham would follow her brilliantly funny Marc Jacobs ad campaign. And here's the answer. Giorgio Armani has just announced she will be the new face of Emporio Armani Women's Underwear worldwide. The S/S '09 campaign will be shot by photographers Mert Alas and Marcus Piggott. 'Who better than Victoria Beckham to launch our new global Emporio Armani underwear campaign?' Mr Armani said today. 'Victoria is a style icon, a dynamic lady whose influence and recognition will add great excitement to the continued international growth of our Emporio Armani women's underwear business.' For a woman who has famously said she hates showing off parts of her body, especially her stomach, this is a brave move. But one we can't wait to see...
Victoria Beckham to shoot Emporio Armani campaign
29 October 2008
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Don't give your mind permission to get disturbed. A disturbed mind is easily influenced. This will cost you your peace. Learn to maintain your peace by freeing yourself from attachments. Competing or comparing yourself with others will not allow you to focus inwards. An inner focus allows you to keep your eye on your higher self. Remember your original nature. It allows you to forge a link with the Divine. Then it becomes easy to recognise useless thoughts and replace them with a spiritual perspective. A calm mind is not just peaceful, it is focused, self-directing and Divine.Unknown
A racing mind that reacts sensitively to little things indicates thinking that has lost its spiritual strength. Meditation restores that power.Unknown
True meditation can never be done with the mind. Very often we make a mistake when we say that we are meditating in the mind and utilising the mind. Real meditation is done in the psychic being and in the soul. It goes hand in hand with flaming aspiration, the burning flame that wants to climb up to the Highest.Sri Chinmoy
Meditation' is a most complicated and most fulfilling word. When we meditate without knowing how to meditate, when we meditate with our mind, it is most complicated. But when we meditate with our inner conviction, with the feeling of divinity within us, it becomes most fulfillingSri Chinmoy
When you meditate you have to try to quiet and calm the mind. There should be no thought within the mind. Right now you feel that if you can cherish twenty ideas at a time, then you are the wisest man on earth. The more thoughts that enter into our minds, the more clever we feel we are. But in the spiritual life it is not like that. If consciously we can make the mind calm and quiet, we feel that a new creation dawns inside us.Sri Chinmoy
Freedom of the mind requires not only, or not even especially, the absence of legal constraints but the presence of alternative thoughts. The most successful tyranny is not the one that uses force to assure uniformity, but the one that removes awareness of other possibilities.Alan Bloom
Krishna consciousness is not something imposed on the mind. On the contrary, it's already inside of each of us, waiting to come out, like fire in a match. Chanting Hare Krishna brings out that natural, pure state of mind.Unknown
Suspicion always haunts the guilty mind; the thief doth fear each bush an officer.William Shakespeare
Think not that guilt requires the burning torches of the Furies to agitate and torment it. Their own frauds, their crimes, their remembrances of the past, their terrors of the future,--these are the domestic furies that are ever present to the mind of the impious.Robert Hall
People are generally better persuaded by the reasons which they have themselves discovered than by those which have come in to the mind of others.Blaise Pascal
Music is no different from opium. Music affects the human mind in a way that makes peoplethinkof nothing but music and sensual matters† Music is a treason to the country, a treason to our youth, and we should cut out all this music and replace it with something instructive.Ayatollah Ruhollah Khomeini
The perversion of the mind is only possible when those who should be heard in its defense are silent.Archibald MacLeish
The cruel irony is that abortion has been presented as something that would set a woman free. This brings to mind the gypsy in Verdi's opera Il Trovatore. Outraged by the count's cruel injustice, she stole his infant son and, in a crazed act of vengeance, flung him into the fire. Or so she thought. For, in turning around, she discovered the count's son lay safe on the ground behind her; it was her own son she had thrown into the flames. Abortion can present itself as glittering liberty, a defiant way to cast off the shackles of injustice. That illusion lasts only until you realize who it was that you threw into the flames. So the second point to make when trying to persuade is that abortion hurts women; it does not deliver on its promise to liberate them.Frederica Matthewes-Green
You'll never succeed in idealizing hard work. Before you can dig mother earth you've got to take off your ideal jacket. The harder a man works, at brute labor, the thinner becomes his idealism, the darker his mind.D. H. Lawrence
Every player, in his secret heart, wants to manage someday. Every fan, in the privacy of his mind, already doesLeonard Koppett
No man is ever whipped until he quits in his own mind.Napoleon Hill
Genius is the ability to put into effect what is on your mind.F. Scott Fitzgerald
When I read great literature, great drama, speeches, or sermons, I feel that the human mind has not achieved anything greater than the ability to share feelings and thoughts through languageJames Earl Jones
The disease with which the human mind now labors is want of faithRalph Waldo Emerson
You cannot plough a field by turning it over in your mind.Unknown
The essence of our effort to see that every child has a chance must be to assure each an equal opportunity, not to become equal, but to become different - to realize whatever unique potential of body, mind and spirit he or she possessesJohn Fischer
The primacy of the word, basis of the human psyche, that has in our age been used for mind-bending persuasion and brain-washing pulp, disgraced by Gobbles and debased by advertising copy, remains a force for freedom that flies out between all bars.Gordimer, Nadine