text:
Yes! Mi Amor Studio is also a full service hair salon!!
We also provide salon services for Bridal Parties and Special Events, please contact us for additional information!
Starting this Tuesday, 05/07/13 , we are doing airbrush tanning for half off!
One tan is originally $30, imagine spending only $15 for a tan that lasts over a week!
Half off tans are available every tuesday between the hours of 10am-4pm!
Call 405-226-4646 to schedule your appointment today!
Be Prepared for your tan!
Step one: Make sure to exfoliate the skin the before your tan. This will ensure an even tan as well as longer lasting results. Who doesnt want their tan to last longer?
Step two: Wear lose/ baggy clothes to your tanning session. This will help protect your tan from any lines or streaks.
Step three: DO NOT WEAR MAKEUP OR DEODORANT TO YOUR TANNING SESSION. If you have deodorant or makup on where the tanning solution sprays, it will turn green. Not permantently, but you will look pretty funny until you take a shower.
Step four: Do not shower again until 8 hours after your tanning session.


text:
You must log in to access this feature. Sign in with Twellow or Facebook to get started.
By signing in to Twellow, you indicate your agreement to our terms of service.
Simply connect with Facebook and kiss those password blues away,
or go here to reset your password.
Innovating@Sun brings you the latest in technology innovations from Sun Microsystems. Tweets by @Marianne_S_.

subset: commoncrawl


text:
Jungle Bobs Kittens Now email@example.com
More information about Jungle Bob (Jungle) Exotic Cats is on Wikipedia. JUNGLE BOB KITTENS NOW!!!! F3 & JUNGLE/COONS F4
I LOVE THESE BIG CATS Very wild looking, Large & EXOTIC!!!!
Jungle/Coon kittens F4 Bob/Tails Mother is Jungle/Coon F3 ---Father is "Flash (Maine Coon) $500/pet price 13 weeks old Three females--all males SOLD Very social & make wonderful family pets--no special permit. No shipping firstname.lastname@example.com Phone 510-7992540 Thanks ""Pj
Don't miss out on these special Jungle hybreds``` NOW Jungle/Bob kittens F4 ``11 weeks ``2 females $500 One has a tail & looks like a Bengal!! The other is a beautiful Marble/no tail--very Exotic looking```
Call & set up a appointment 510-7992540 NO SHIPPING
Below--Jungle breeders (Not for sale)
Two Jungle females F2 meeting!!!


text:
The panic and fear commenced around noon.
I wanted one weekend to not stress over lesson plans but couldn't pull off getting them written during my planning so now I'll be up forever working on them tonight.
After work I went out to eat with my childhood BFF and her kid and husband which kicked off a whole other set of emotions.
Then the feelings inadequacy crept in and which led to more stress over my job and pretty much everything else in my life.
So I started crying on the way home and kind of haven't stopped since then.
27 is going to be amazing. I can feel it.
p.s. My parents sent me flowers today so at least I'm not totally unloved.


text:
@crunkyeti Lovely girl.
you know how when you go to a friend's after the bar with some people are passing out and you decided you will just go to bed in the guest room but there is a guy sleeping with a hard cock in there and you just have to suck him. No? guess it was just me then.


text:
Get ideas and inspiration, find easy to use patterns
and tutorials for your next sewing project.
by kathhhhhy
by poppykettle
by steph1230
by everfive
by SewingDenise
by tiffanee
by carolyn-s
by johnnyc8688
by Xiaofeng Xu
by kathsavery
Meg's Magazine Mash Up 2014
Check out Meg's finished Mash Up project of her denim suit and see how you can sew along!
Fashion & Trends
Dress like your favorite heroine from Disney's Frozen.
Web Seminar
This web seminar will teach you tricks to sewing and cutting silk successfully!
See one of the techniques you'll learn in November's Fabric Design course.
Editors' Pick
Cozy scarf collars, dressed up sweats, and essential dresses.
Make the Square Neck Jersey Dress with Darts
You must allow our "request for permission" request to login to Burdastyle with Facebook.


text:
Before you start sharpening your pitchforks or preparing your lobotomy machines, let me explain myself.
Steve Delabar has great strikeout stuff
For a man who had temporarily retired from the game of baseball entirely, Steve Delabar really came back with a vengeance. After a full season with both the Mariners and the Blue Jays in 2012, the 29 year old posted a swinging strike percentage of 15.8%, good for 4th among qualified relievers in the majors. The three relievers ahead of him were Craig Kimbrel, Aroldis Chapman and Joaquin Benoit, with Delabar ahead of closers Sergio Romo, Jason Grilli, Ernesto Frieri, Jason Motte and Fernando Rodney. In addition, Delabar's K/9 was good for 8th in the majors at 12.55/9 innings. While there are a lot more qualities needed to become a closer, having lights-out stuff last year puts him in league with some of the game's best 9th inning men.
Steve Delabar had juxtaposing excellent and terrible partial season stats between Seattle and Toronto
While he was always a strikeout machine, Delabar had wildly-swaying stats between the Mariners and the Blue Jays. For example, on Seattle Steve Delabar had a strong collection of stats in 2.70 BB/9, 0.93 WHIP and a .183 BABIP, yet was held to a -0.4 fWAR over 36.2 innings. The problem was that he gave up too many HR's, with a HR/FB rate of 27.3% and a 2.21 HR/9, with led to a 4+ ERA. After coming to Toronto he posted a 0.6 fWAR over 29.1 innings, in a large part because of his 14.11 K/9 and much improved HR stats, like 0.90 HR/9 and a very respectable 10.7% HR/FB rate. This led to a lower ERA at 3.38 with the club and a 2.82 FIP. But what is surprising is that with the Blue Jays Delabar posted a 4.60 BB/9, a .323 BABIP and 1.30 WHIP. If Steve Delabar were to replicate his Blue Jays numbers over a full season, he could expect to bring in roughly 1.3 fWAR; a perfect combination between his Seattle control numbers and his Toronto strikeout/low HR numbers and Delabar would be well on his way to becoming an elite reliever. We'd have to see what a full season of Steve Delabar with the Blue Jays will provide, which leads to…
Steve Delabar's contract years allow Anthopoulos to unleash him as a closer with perfect timing
(This last section is a lot more speculative than quantifiable, but that's the kind of thing required when making a bold prediction.) Current Blue Jays closer Janssen's final guaranteed season is in 2013, with a $4M option in 2014 with no buyout. Santos' final guaranteed year with the team is in 2014, with club options for $6M, $8M and $8.75M over 2015-2017 and $750,000 buyouts for each year. In a greater viewpoint, there is no Blue Jays player guaranteed a contract year beyond 2015 without going to arbitration. The team might be looking to save their money if they want to keep some of their big name players like Jose Bautista, Edwin Encarnacion and Brandon Morrow. That's where inserting Steve Delabar as an affordable closer option comes in.
At the moment, Steve Delabar has 1.015 service years in the MLB. During the 2014 off-season, he will be up for his first year of arbitration. Anthopoulos would be smart to utilize Delabar in the 7th inning for 2013, use him as a setup guy in 2014 and take him to arbitration during the off-season. That way the Blue Jays would be able to sign Steve Delabar for setup man dollars and use him as a closer later, much like how the Pirates signed Jason Grilli for 2 years/$7M and then traded Joel Hanrahan to use Grilli in a closer role for 2013.
Regardless of what the Blue Jays do going forward, with Steve Delabar under team control for the next 5 years the team has an exciting pitching option with electric stuff. Hopefully the 29 year old can remain patient, work on his control and keep the ball in the yard over the next few years. If so, Anthopoulos might not need to look for a free agent closer for quite some time.


text:
Top-Rated International Nonprofits - 2012/Top-Rated Awards
Are you interested in donating, giving to or volunteering at a charity but not sure which ones are truly making a difference? Browse this list of Top-Rated Nonprofits focused on International and find the most distinguished charities in your area. Learn about their programs, see their ratings and reviews, and choose from some of the very best International nonprofits that the world has to offer! Discover all of the great charities below that have won a GreatNonprofits Top-Rated Award. And if you already know of a great nonprofit involved with International add them to this list by writing a review!
136 Top-Rated Nonprofits
Top-Rated By Issue
Top-Rated By Location
Top-Rated By Campaign
Jerusalem, Israel
18 ratings
Paris, France
Toronto, Canada
13 ratings
12 ratings
Acton, CA
32 ratings
Berkeley, CA
69 ratings
Berkeley, CA
34 ratings
Carlsbad, CA
41 ratings
Diamond Bar, CA
60 ratings
Escondido, CA
71 ratings
Foster City, CA
42 ratings
Huntington Beach, CA
26 ratings
Irvine, CA
11 ratings
Milpitas, CA
24 ratings
Modesto, CA
72 ratings
Oakland, CA
Pleasanton, CA
37 ratings
Portola Valley, CA
33 ratings
Sacramento, CA
308 ratings
San Diego, CA
355 ratings
San Francisco, CA
114 ratings
San Francisco, CA
47 ratings
San Francisco, CA
91 ratings
San Francisco, CA
133 ratings
San Francisco, CA
17 ratings
San Mateo, CA
38 ratings
San Rafael, CA
15 ratings
Santa Monica, CA
31 ratings
Sausalito, CA
99 ratings


text:
Sparrow 1.5 is here. It brings 3 of the most requested & awaited features!
First. Dropbox.
Drag, drop, send (and sync). Sending a mail with attachement has never been simpler. And without even noticing it, you are syncing your files in the cloud making sure you never lose them.
Second. Block remote images.
Keep control of the images displayed in your mail: once or always.
Third. Search.
With it's new smart search & Gmail-like tokens, find the mail you're looking for in a matter of seconds.
Already a Sparrower? As always, this update is completely free for you. Check for update or visit the Mac AppStore and enjoy the new features.
If you're new to Sparrow, you can get the lite version here or get the full version for $9.99.
Best mail app for OS X if you use GMail.
- Reblogged from Sparrow


text:
About Us
Zero Tolerance Knives
Zero Tolerance Knives
Zero Tolerance Knives
Zero Tolerance 0300 Knife Series
Zero Tolerance 0350 Knife Series
Zero Tolerance 0560 Hinderer Design - Black Folding...
Zero Tolerance 0300ST - ZT 0300ST
Zero Tolerance Knives Authorized Dealer
. ZT stands for Zero Tolerance Knives, this fine company strives to create knives with zero tolerances and of the highest caliber. ZT knives are top in the combat and tactical knives. Zero Tolerance knives utilize the best designs from knifemakers such as
Ken Onion
Rick Hinderer
Strider Knives
. Zero Tolerance Knives are built with the best materials and blade steels - at extremely high tolerances with excellent fit and finish. A ZT knife is proudly Made in USA. Some of the more popular ZT knife models are the:
Zero Tolerance 0300
Zero Tolerance 0350
and the
Zero Tolerance 0550
KnifeArt.com is an authorized dealer for Zero Tolerance Knives. We stock t
he knives you see at our website. We ship ZT knives on a regular basis to members of the US Military (APO/FPO) via USPS Priority Mail.
Zero Tolerance Knives Product Guide & Review
Zero Tolerance tactical knives are made to exacting specifications in Tualatin, OR by KAI USA, parent company of Zero Tolerance, Kershaw Knives, and Shun kitchen cutlery. The Zero Tolerance name in the knife industry carries serious weight with it, as KAI USA engineered this line of professional grade tactical knives to serve individuals who are in the law enforcement and military circles. These job fields rely on equipment to complete a mission successfully, help keep our streets safe, and most importantly, serve as tools to those who risk their lives every day for our safety. Currently the Zero Tolerance product line encompasses compact fixed blades, full size fixed fighters, robust tactical folders of the assisted opening and manual opening varieties, and automatic opening knives. These knives are engineered to withstand the toughest punishment given to them in real-life scenarios at home and abroad. Professionals everywhere the world over, can trust a Zero Tolerance knife to never fail and serve adeptly as both a tool, and a weapon should the dire need arise. Progressive designs, the use of premium materials, and 3D CNC machining culminate in what defines a Zero Tolerance knife.
Tactical folders are what's hot in today's market and the Zero Tolerance product lineup features no shortage of this style of folding knives. Look at any one of the folders really good, and the word "robust" definitely comes to mind. The
Zero Tolerance 0200
is a stylish yet tough as nails manual opening folder with a recurve 154CM blade and 3D machined black G-10 handles. The handle fills your grip and feels very secure. For those wanting something a bit stouter, check out the
Zero Tolerance 0300
series. This piece features a wide, modified drop point blade of S30V, set into a handle that has a half-and-half construction style. The lock side of the handle is machined from titanium, while the non lock side has a single full liner encased by your choice of black or green G-10 handles. The
Zero Tolerance 0300
comes standard with the Speed Safe assisted opening for rapid one hand deployment.
You say like dig the ZT 0300 but find it too big for your needs? Then try downsizing a bit to the
Zero Tolerance 0350
. Sharing the exact same design lineage as the
Zero Tolerance 0300
, the
Zero Tolerance 0350
is a more pocket-able size with an S30V blade and flat ground S30V blade. If you wish for something more aggressive in appearance, then look no further than the ZT 0400. It's a sexy little number with an ergonomic aluminum handle with grip tape inlays for enhanced grip traction. The blade is an S30V tango recurve. Also equipped with Speed Safe, the zero tolerance 0400 is quick to deploy in any situation. For those looking for definite hard working folder design in manual opening format, take a hard look at the
Zero Tolerance 0550
Zero Tolerance 0560
folders. Both were designed by popular
custom knife
Rick Hinderer
of Wooster, Ohio, these knives exhibit quite a few of Hinderer's trademarks such as the useful clip point and drop point blades, ergonomic handles with half-and-half construction style that also has a support liner for the non-lock side, and dual thumb studs which serve as the blade's positive stop in the open position. The
Zero Tolerance 0550
is a meaty folder that offers a great grip and its frame lock design locks up sure and solid. Blade material is Vanax, European high performance steel that is of particle metallurgy technology. The
Zero Tolerance 0560
is a larger design, boasting a modified drop point blade with flipper/finger guard, half-and-half handle construction with 3D machined G-10 and titanium. There is also Zero Tolerance's own KVT bearing system in the pivot, which makes blade opening effortless and smooth as glass. Blade steel is Elmax, another popular European high performance blade material that exhibit qualities similar to that of the industry standard CPM S30V. And finally, we have the exciting
Zero Tolerance 0777
folder. This model is a departure from the norm of what Zero Tolerance tactical folders are about. This model blends carbon fiber, titanium, damascus, and N360 stainless steel into one eye catching and stylish folder. The blade is a composite blade, using KAI USA patented technology to affix two different blade materials together to form one blade. The
Zero Tolerance 0777
has a blade spine of Devin Thomas herringbone damascus, with a cutting edge of Bohler N360 stainless. The handle is carbon fiber, with a sub-framelock for strength and light weight. What is really cool is the lock bar's engagement plate can be adjusted by the user to tailor the lockup of the folder and to compensate for any slight wear-in that will happen. The
Zero Tolerance 0777
is a fresh and exciting design and a departure for Zero Tolerance from the usual Mack truck tough down-and-dirty tactical folders. There are other Zero Tolerance folder designs to choose from, but these are the highlights of the product lineup as it stands currently.
So, you want to get fixed? As in fixed blade that is! Zero Tolerance has you covered with several fixed blades, each offering their own unique flavor and duty specialties. The classic dagger style never goes out of fashion with its perfect symmetrical appearance and blade ground symmetrically as well, thin enough to piece thick materials. Zero Tolerance puts their unique spin on this classic design with their
Zero Tolerance 0150
boot knife. At 7 ˝ inches overall, this knife sports a dagger blade of S30V and a machined G-10 handle. A black Kydex, MOLLE compatible sheath rounds out this package. The
Zero Tolerance 0160
is a more straightforward style with a clip point blade and a machined G-10 handle. Blade steel is 14C28N, Sandvik's exclusive steel for KAI USA. Another favorite is the
Zero Tolerance 0121
with its stout and compact stature. This knife tucks in easily where other knives of longer length cannot. It also features a sharpened, recessed cutting slot behind the main cutting edge to cut monofilament or string easily and quickly. The
Zero Tolerance 0170
is a full sized fighter style with a drop point blade of 14C28N and a handle which features two finger choils and a pronounced thumb rest for ease of gripping. The ZT 0170 was expertly designed by knifemaker RJ Martin. Perhaps the most unique of all Zero Tolerance fixed blades is the ZT-9 bayonet, co-designed by Zero Tolerance and
Strider Knives
. The ZT-9 takes the basic bayonet and hot rods it, using S30V stainless steel, green G-10 handles, and stainless steel hardware. Unlike your much cheaper bayonets, the ZT-9 is built to last! It also mounts easily to M-16, M-4, and AR-15 rifles. As with the folders, there are other fixed blades in the Zero Tolerance lineup, so what's discussed herein is not the entire product line.
Whatever your case may be, you owe it to yourself to take a look at the entire Zero Tolerance product family to get a sense of what this brand is all about. With as many commercially produced tactical knives as there are on the market, the Zero Tolerance products always are held in high regard by many knife enthusiasts, as well as being stand-outs in their own class. Nothing performs like Zero Tolerance knife.
Zero Tolerance 0801 BW Todd Rexford Design Folding Knife
Zero Tolerance 0300 BW Blackwash Tactical Folding Knife
Zero Tolerance 0300 Knife - ZT 0300
Zero Tolerance 0301ST Serrated
Zero Tolerance 0301
Zero Tolerance ZT 0350SWCF Carbon Fiber Assisted Opening Folding Knife
Zero Tolerance 0350 Folding Knife
Zero Tolerance 0350ST Knife - ZT 0350ST
Zero Tolerance 0350SW Tactical Folding Knife
Zero Tolerance 0200 Knife - ZT 0200
Zero Tolerance 0200ST Military Tactical Folding Knife - ZT 0200ST
Zero Tolerance 0550 S35-VN Tactial Folding Knife
Zero Tolerance 0560 Hinderer Design - Black Folding Knife
Zero Tolerance 0561 Hinderer Design - ZT 0561
Zero Tolerance 0560 BW Blackwash Tactical Folding Knife
Zero Tolerance 0560BLK Black Blade Folding Knife
Zero Tolerance 0770CF Folding Knife - Carbon Fiber Frame
Zero Tolerance 0566CF Hinderer Design Carbon Fiber Folder
Zero Tolerance 0566BW Hinderer Design Folding Knife
Zero Tolerance 0121 Fixed Blade Knife
Zero Tolerance 0100 Fixed Blade Knife - ZT 0100
Zero Tolerance 0160 Shifter Fixed Blade Knife
Zero Tolerance 0566BWCF Black Wash and Carbon Fiber Folder
Zero Tolerance 0801 Todd Rexford Design Tactical Folding Knife
Zero Tolerance 0801CF Copperhead Todd Rexford Limited Edition
Zero Tolerance 0300ST - ZT 0300ST
Zero Tolerance 0350BW Blackwash Assisted Opening Folding Knife
Zero Tolerance 0350TS Tiger Stripes - ZT 0350TS
Zero Tolerance 0350TSST Tactical Folding Knife
Zero Tolerance 0700 Tactical Folding Knife
Zero Tolerance 0560CBCF Folding Knife
Zero Tolerance 0566 Rick Hinderer Design Tactical Folding Knife
Zero Tolerance 0620 Emerson Design - G10 & Elmax
Zero Tolerance 0150 Boot Knife - ZT 0150
Zero Tolerance 0170 Fixed Blade Knife - ZT 0170
Zero Tolerance ZT-9 Strider Design Bayonet Fixed Blade Knife - ZT 9
Zero Tolerance 0777 M390 Folding Knife - ZT 0777 M390
Zero Tolerance 0888 Folding Knife
Zero Tolerance 0600 Folding Knife
Zero Tolerance 0770 Tactical Folding Knife
Zero Tolerance 0454 Knife - Coming Soon
Zero Tolerance 0600BLK RJ Martin Design Flipper Folding Knife
Zero Tolerance 0620CF Emerson Design - Carbon Fiber & M390
Zero Tolerance 0620BLK Emerson Design - G10 & Elmax
Zero Tolerance 0102 Tactical Tomahawk
Zero Tolerance 0562CF Hinderer Design - Carbon Fiber & M390
Zero Tolerance 0562 Hinderer Design - G10 & Elmax
Zero Tolerance 0180 Fixed Blade
Zero Tolerance 0300 Knife Series
Zero Tolerance 0350 Knife Series
Our customers utilize our
years of experience
to bring them the best knives in the world. We focus on
quality and service
Site Updated:
Read more...
Sign up today
to receive special offers from Knife Art!
About Us
Chris Reeve Knives
William Henry Knives
Strider Knives
Hinderer Knives
Spartan Blades
Emerson Knives
Benchmade Knives
See All
Tactical Folding Knives
Tactical Fixed Blade Knives
Hunting Knives
Damascus Knives
Upscale Pocket Knives
Survival Knives
See All
Tactical Pens
Tactical Watches
Money Clips
Knife Accessories
See All
Chris Reeve Knives
William Henry Knives
Zero Tolerance Knives
Rick Hinderer Knives
Custom Folding Knives
Benchmade Knives
Emerson Knives
Engraved Knives
Tactical Custom Knives
Custom Hunting Knives
Custom Knives by Price
Custom Knives
Custom Knives by Maker
Strider Knives
Strider PT
Strider SNG
Strider SMF
Spartan Blades
Tactical Pens
Traser Watches
Military Watches
Rick Hinderer
Knife Brands
Chris Reeve Knives
William Henry Knives
Strider Knives
Benchmade Knives
Emerson Knives
Fantoni Knives
Rick Hinderer Knives
Spartan Blades
Zero Tolerance Knives
KnifeArt Knives
Knife Brands
Brous Blades
Winkler Knives
Bastinelli Creations
Kingdom Armory
Freeman Outdoor Gear
Boye Knives
Attleboro Knives
Lion Steel Knives
Microtech Knives
Gear Brands
Lenslight Flashlights
Starlingear Beads
Traser Watches
Sharpening Stones
Knife Types
Folding Knives
Tactical Folding Knives
Damascus Knives
Engraved Knives
Survival Knives
Hunting Knives
Tactical Fixed Blades
Multiblade Pocket Knives
Rigging Knives
American Made Knives
Assisted-Opening Knives
Knives by Price
Knives under $500
Knives $500-$1000
Knives $1000-$2000
Knives over $2000
Custom Knife Makers A-M
Jens Anso
Arno Bernard
Duane Dwyer
Emerson Knives
Crusader Forge
Brian Fellhoelter
Stanley Fujisaka
Les George
Rick Hinderer Knives
Mike Irie
Kirby Lambert
Liong Mah Design
Sal Manaro
Matthew Martin Pens
Kansei Matsuno
Scot Matsuoka
Don Morrow
Custom Knife Makers N-Z
Hiroaki Ohta
Rod Olson
Mel Pardue
Darrel Ralph
Chris Reeve Knives
Dennis Riley
Ken Steigerwalt
Mick Strider
Brian Tighe
Warren Thomas
Andre Thorburn
Marty Young
Winkler Knives
Flashlight Brands
Lenslight Flashlights
Money Clip Brands
William Henry Money Clips
Lion Steel Money Clips
Vox Money Clips
Pens / Tactical Pens
Tuff Writer Pens
Hinderer Pens
Matthew Martin Pens
Benchmade Pens
Hidetoshi Nakayama
Brian Fellhoelter
William Henry Pens


text:
Moon Photo
7704 Greenwood Avenue North, Seattle, United States
Email: firstname.lastname@example.com
Website: http://moonphotolab.com/
Phone: (206) 783-3377
- Does 35mm film development
- Does 120 (medium format) film development
- Does C41 film development
- Does black and white film development
Professional Black & White and Color Processing
Moonphoto is a photo lab that makes higher quality pictures from both film and digital sources. We do traditional black and white prints on fiber and resin coated papers, and color prints on photographic and archival papers. We offer the finest restorations of old photographs. Digital services include film and print scanning, retouching, file adjusting, and giclée printing.
e opened our lab in 1974, when we saw a need for a professional Black and White photo lab in the Seattle area. We wanted to do something we were good at, that we liked to do, and that was needed: high quality black and white. Develop the film, print the negatives. On fiber, or resin coated paper. Tone it if you like. Quality always.
From the first location, our business grew steadily, and in 1987 we opened a second shop. In 1994 we began offering scanning, retouching, and color digital prints. In 2000, we again expanded our services to include color film processing and printing. In 2005 we upgraded our scanning and digital printing services, offering better whole roll scans and Giclée prints.
We still develop our true black and white film by hand, and do traditional B&W printing on enlargers by hand, using classic methods and materials. We believe traditional black and white photography is here to stay, though it will occupy a smaller niche. The exquisite quality if film and an optical fiber print is something special, and is not duplicated by the latest digital methods. Film is still a vaible option.
We will continue to offer the finest in traditional black & white processing and quality color prints. We continue to provide high quality scanning and unsurpassed restorations of treasured old photographs. Digital capture and editing of images has its advantages, and we have now embraced the best digital printing methods.
Over the past 34 years, our success has been confirmed by the praise and recommendations of many photographers, both professional and amateur. We can thank our staff, present and past, who have helped us with good work and suggestions along the way. It is only with the concerted honest work of many people that a business like ours can keep going for over 30 years. A special thanks to our valued customers, some of whom have been with us from the beginning. Thanks for your support!
Be the first to recommend this PhotoLab
Recommending PhotoLabs helps others find the best places to handle their film.
No comments yet, be the first
Do you want to submit a new PhotoLab?
Are we missing some Photolabs? Share your wisdom and help the Lomographic community!


text:
Star sire and exceptional athlete
Dressage stallion in demand worldwide. Under his rider Kristina Sprehe, Desperados crowned his already unique career with a team silver medal as member of the German team at the 2012 Olympic Games in London, where he also took eighth place in the individual result. In 2013, they belonged to the gold team at the European Championship in Herning and were on fifth place in both, the Grand Prix Special and Freestyle.
Desperados' performance record is impressive. But also in breeding, Desperados is as safe as a bank. His offspring are convincing due to their good looks, good type and excellent movements. All over Germany he has supplied absolutely top foals for many foal shows and auctions, often selling for five-figure prices. Up to now, 24 sons are licensed. Among them are Destano (main premium winner Vechta 2012), Derby Dancer (State Stud Warendorf), Double Joy (private stallion Westphalia), Decurio (premium stallion/State Stud Saxony-Anhalt), Download (private stallion Hesse), Descolari (reserve champion Neustadt/Dosse 2012), Duisenberg (private stallion Westphalia), Desperando (private stallion Oldenburg) and several others.
Two times in a row, Desperados presented the Champion mares at the Herwart von der Decken Show 2010 and 2011, namely Doris Day and Delany. Doris Day became Bundechampion in Warendorf in 2010, after being nominated Hanoverian Champion in Verden. Several daughters were awarded the state premium. According to the German FN's predicted breeding value statistics, Desperados belongs with 141 points to the top one percent of all German stallions. Furthermore, Desperados received the Grande award from the Hanoverian Verband on the occasion of the gala evening of the 126. Elite Auction in spring 2012.
Further information:
Stations of a career: Desperados was awarded a premium at the Hanoverian licensing in December 2004 in Verden. He passed his 30-day test in Schlieckau with the highest scores (including a 9.5 for his canter and a 9.0 from the guest riders). Numerous victories in tests for young riding horses, including the 2004 Hanoverian Championships in Verden as well as bronze twice at the Bundeschampionat in Warendorf in 2004 and 2005 are on record. After further training with Falk Rosenbauer, he won and placed in St. Georg and Intermédiaire I among strong competitors, also in Hamburg and Neumünster. In 2009 he successfully competed in the Final of the Nürnberg Burg Pokal. After winning the 2010 German Dressage Derby he placed also in the final of the Media Cup. In 2011 Kristina Sprehe took her place in his saddle and lead him to international Grand Prix successes. Desperados was also awarded the Otto Löhrke Prize as Germany's best young Grand Prix horse. Further victories in Grand Prixs like in Rotterdam/NED, Verden, Oldenburg and Stuttgart speak a clear language. The year 2012 started brilliantly: In Dortmund's Westfalenhalle the couple dominated the world's best at the show in Grand Prix Spécial and brought themselves into discussion for the German Olympic team when they competed at the show in Hagen, took the bronze medal at the German Championships in Balve two times and then again at the final review in Aachen. In 2013, he won in Dormund, Perle-Borg and at the CHIO Aachen.
The black Hanoverian stallion De Niro won the I-a main premium in Oldenburg in 1997 based on his own record in sport and the quality of his first crop. By the time De Niro was seven, he made a successful debut in the Grand Prix dressage ring and later collected numerous first place ribbons in Nations Cups, the German Dressage Derby and at the German Championships for Professional Riders. In 2008 he was bestowed a special honor: the "Hanoverian Stallion of the Year" award. His dam, Wie Musik, is by Wolkenstein II. This chestnut stallion was the Reserve Champion of the 1992 licensing in Verden, 1993 Bundeschampion of German Riding Horses in Mannheim and won his stallion performance test in Adelheidsdorf in 1993. A full-sister of his dam Wie Musik, named Wie Platine, took third place in the 2001 Bundeschampionat for German riding horses. Through Matcho AA and Pik König you find heroes from the traditional Oberndorf station on the dam's side of the pedigree. The black French Anglo-Arabian stallion, Matcho AA, won his stallion performance test and is a sire of pronounced versatility. Pik König, the fourth link in his chain of ancestors, has gained a reputation as a maker of dressage horses and show jumpers of the very first order. The Hanoverian dam line 53/Foersaci (by Förstergruß I-Lorenz-Amandus-Lorval-Alpenprinz-Julius-Süd-Y. Gameboy) is also the origin of the licensed stallions Condiro (State Stud Warendorf), Don Marcello (private stallion Hanover), Don Noblesse (private stallion Hanover), Don Placido (AUT), Foster, Limonit and Mister A (both State Stud Celle), Londontower (private stallion Mecklenburg), Moseltal and Rocko Barocko (private stallion Mecklenburg) as well as the successful show jumpers Akrobat/Henrike Konzag and Rosalinde/Eric Lamaze/Canada.
Licensed for Hanover, Oldenburg, Westphalia and Rhineland as well as all Southern German and new German State Verbands.
Breeder: Herbert Schütt, Hemmoor


text:
"The only people who seem to have nothing to do with the education of the children are the parents.
Find a translation for this quote in other languages:
Select another language:
Discuss this G.K. Chesterton quote with the community:
Use the citation below to add this quote to your bibliography:
"G.K. Chesterton Quotes." Quotes.net. STANDS4 LLC, 2014. Web. 31 Oct. 2014. <http://www.quotes.net/quote/35973>.


text:
Holy Transfiguration of Christ Cathedral
349 East 47th Avenue, Denver, Colorado 80216 (303) 294-0938
Wednesday Evening Vespers 6:30 PM,
Saturday Evening Vespers 5:00 PM,
Hours 09:00 AM Sunday Divine Liturgy 09:30 AM
Metro Area
116 years!
Added "Rites of Burial" to Bulgakov Handbook
Added "Place of Administration of the Office of Burial" to Bulgakov Handbook
Added Grace Christus Concerts to benefit Huntington's Disease Society of America
Added "Time of Burial" to Bulgakov Manual
Sunday Bulletins are added each week for your reference. Roll your mouse over "Home" on the left had side of this page and select "Sunday Bulletins"


text:
Cybercrime: What It Is and How to Protect Yourself
Cybercrime is any action that uses a computer system or network as a weapon or an accessory in crime, or when a computer serves as the target of the act being committed.
Some of the most common forms of cybercrime include attempts to steal information by penetrating networks via malicious hacking, hijacking of online accounts and remote takeovers of computers to repurpose them for cybercrime.
Cybercrime can involve software that is invasive and hostile to the targeted computer or its user. Such malicious software is commonly called malware.
User-targeted crime
Network penetration is often carried out by groups of malicious hackers seeking access to protected files or databases in order to copy sensitive personal, corporate, financial or even political information.
Malware is often used to exploit flaws in a network's security system. For example, malware can be hidden in files attached to emails sent to users within a targeted organization. The end result is a data breach — the unauthorized copying of secured data.
Hijacking online accounts can be as simple as guessing a legitimate user's password or correctly answering password-reset questions. Hijacked webmail and social-networking accounts can be used for identity theft, to blackmail targeted users into cooperation, or to purchase goods and software and redirect the items' delivery to the hijackers.
Remote takeovers of computers "enslave" thousands of PCs without their legitimate users' knowledge. Such "zombie" computers, secretly controlled by cybercriminals, are used to pump out spam emails, place ads or malware on infected websites or even knock websites offline in distributed denial-of-service attacks.
Another popular variant of cybercrime includes fraudulent activities intended to steal money from the computer user.
These attempts may take the form of a "phishing" email message, such as the familiar Nigerian 419 or advance-fee scam, or more sophisticated "banking Trojans," malware that infects Web browsers and hijacks online banking sessions, transferring money from victims' accounts to accounts controlled by criminals.
Computer users often unknowingly install malware on their machines. Some freeware programs deliberately conceal malware payloads, corrupted websites can infect visiting browsers, and many users unquestioningly open email attachments from trusted sources.
User-initiated crime
Crimes in which a computer user is targeted by another party are common, but many users also rely upon their computers to commit crimes of their own.
By far, the most popular such cybercrime is online piracy. From exchanging songs with friends via peer-to-peer networks to streaming or downloading movies, television shows and software from unauthorized hosting sites, piracy is a growing problem for the entertainment and software industries.
Other cybercrimes include cyberbullying, the harassment of targeted individuals through the Internet, often via social networks, and the viewing and distribution of child pornography.
Protecting a computer system from cybercrime
There is no magic solution to prevent becoming a target of a cybercrime, but there are several steps that can be taken to alleviate the risks.
First, experts recommend installing an anti-virus package on every computer that connects to the Internet. Anti-virus software can keep out malware and other threats.
Computer users also need to use common sense and develop an understanding of patterns often seen in scams online; this can help reduce the number of individuals who fall prey to criminals on the Internet.
By taking care to download only trusted files, run an updated operating system and use security software to keep out threats, users can greatly diminish their chances of becoming a victim of cybercrime.


text:
Please confirm that your email address is correct, so you can successfully receive this alert.
OBJECTIVE: Heterotrimeric G proteins were previously implicated in the biochemical mechanisms underlying the pathophysiology and treatment of mood disorders. Low function and immunoreactivity of G proteins were observed in patients with major depression. In the present study the authors evaluated the effects of ECT on the low measures of G proteins in patients with major depression. METHOD: Repeated G protein measurements in mononuclear leukocytes of 10 patients with major depression were made. Each patient was examined while untreated and after successive sessions of ECT; 14 normal subjects were also studied. G protein function was evaluated through β-adrenergic- and muscarinic-agonist-enhanced guanine nucleotide binding capacity, substantiated by quantitative measures of G proteins through immunoblot analyses using polyclonal antibodies against Gsα, Giα, and Gβ proteins. RESULTS: Mononuclear leukocytes of patients with depression showed immunoreactive levels of Gsα and Giα that were significantly lower than those of normal subjects; the depressed patients also had markedly hypofunctional Gs and Gi. The low levels of G protein function and immunoreactivity were alleviated by ECT. Repeated measurements in the same patients after successive ECT sessions showed that the normalization of G protein measures preceded, and thus predicted, clinical improvement. The function and quantity of Gs and Gi proteins in patients given ECT were significantly correlated. CONCLUSIONS: These findings support the implication of G proteins in the pathophysiology and treatment of mood disorders. G protein measurements in patients with depression may potentially serve not only as a biochemical marker for affective state but also for biochemical prediction and evaluation of responses to ECT.
Arole for monoaminergic and muscarinic cholinergic mechanisms in the pathogenesis of mood disorders has been largely suggested by and formulated in the catecholamine hypothesis and in the monoaminergic-cholinergic balance hypothesis of affective disorders (1, 2). Biochemical research in affective disorders has focused on the cascade of events involved in signal transduction: from the level of the primary messenger (the catecholamine or acetylcholine neurotransmitter) to the level of the neurotransmitter receptors and, lately, to information transduction mechanisms beyond receptors, involving guanine-nucleotide-binding G proteins. The family of heterotrimeric G proteins are a crucial point of convergence in the transmission of signals from a variety of hormone and neurotransmitter membrane receptors to a series of downstream cellular events: intracellular second messenger effector enzymes and ionic channels (3, 4). Evidence implicates the involvement of G proteins in the pathophysiology of mood disorders and in the biochemical mechanisms underlying the treatment of these disorders. Hyperfunctional Gs and Gi proteins were detected in mononuclear leukocytes of patients with mania (5, 6), while hypofunctional Gs and Gi proteins were found in mononuclear leukocytes of patients with major depressive disorder (6–9). High immunoreactivity levels and function of Gsα were found in postmortem cerebral cortices of bipolar patients (10–12).
We previously found the function of receptor-coupled Gs and Gi proteins to be altered by lithium (13–19) and other treatments for bipolar disorder (17–19). The results of studies by other groups, using a variety of techniques, have generally agreed with these results and implicate involvement of G proteins in lithium's mechanism of action (20–26). The therapeutic spectrum of ECT, including both depression and mania, is similar to that of lithium and other drugs for bipolar illness. One way of understanding the diversity of ECT's effects on the function of a variety of neurotransmitters and receptors (for review see references 27–29) is to hypothesize that, like lithium, ECT stabilizes disregulated intracellular signaling linked to multiple transmitter systems (27, 29). Indeed, ECT was previously shown to alter various aspects of G protein functioning in animal studies (17–19, 30–32). Searching for the biochemical mechanisms of action of ECT and other treatments used against mood and other mental disorders through animal studies has intrinsic limitations. Usually, mentally disordered patients have disordered neurochemistry that is correlated with their symptomatic state. Thus, the effects of biochemical treatment on normal animals cannot be simply extrapolated to possible biochemical treatment effects in symptomatic patients with known abnormal underlying biochemistry.
Therefore, in the present study we sought to evaluate the effects of repeated electroconvulsive treatments on the low quantitative and functional measures of Gs and Gi proteins in mononuclear leukocytes of patients with major depression, addressing the following questions: 1) Do the dynamics of normalization of Gs and Gi protein function during ECT parallel the dynamics of normalization of Gsα and Giα immunoreactivity? and 2) Does normalization of the biochemical measures of Gs and Gi proteins follow, and thus reflect, clinical improvement or precede, and thus predict, clinical improvement?
All patients were diagnosed according to DSM-IV criteria by at least two senior psychiatrists (G.S., G.R.). The inclusion criteria were normal results of physical examination, ECG, and laboratory tests for renal, hepatic, hematologic, and thyroid function. After complete description of the study to the subjects, written informed consent was obtained for repeated blood examinations. The study was approved by the institutional review board.
The 10 untreated hospitalized patients with major depression had a mean score on the Hamilton Depression Rating Scale of 26.4 (SD=5.7); there were three women and seven men, and their average age was 53.7 years (range=26–72). The healthy volunteer group consisted of 14 subjects, 10 men and four women with an average age of 50.8 years (range=25–74), from the staff of the Beer Sheva Mental Health Center and the staff's families.
ECT was administered twice a week at 3–4-day intervals by means of a MECTA-D apparatus with bitemporal electrode placement. No antidepressant medication was given to the patients during the course of ECT treatment. Anesthesia was induced by sodium pentothal (3.0 mg/kg), and the patients received succinylcholine (1.5 mg/kg), followed by oxygenation. Seizure duration was monitored centrally by the MECTA single-channel EEG monitor. A constant-current bidirectional brief-pulse square-wave stimulus was applied (pulse width, 1.5 msec; frequency, 70 Hz; duration, 1.25–2.00 seconds). In all cases blood was drawn between 8:00 and 10:00 a.m. In the course of ECT, blood was drawn at least 48 hours after the previous ECT session. The Beck Depression Inventory and the Hamilton Depression Rating Scale were administered before blood sampling.
Mononuclear leukocytes were isolated from 60 ml of heparinized fresh blood by using Ficoll-Paque gradient. Cells were homogenized in 25 mM Tris hydrochloride, pH 7.4, and 1 mM dithiotreitol. The homogenate was passed through two layers of cheesecloth to remove debris, and membranes were collected by further centrifugation at 18,000 g for 10 minutes. The membranes were then either freshly used for the functional binding measures or suspended in homogenization buffer containing 1 mM EGTA and 30% sucrose weight per volume and frozen at –70° until assayed by the quantitative measures. Aliquots were taken for protein concentration determination by Bradford's assay.
Binding reactions were carried out for 15 minutes at room temperature in a final volume of 200 µl. The reaction buffer consisted of 25 mM Tris hydrochloride, pH 7.4, 1 mM ATP, 1 mM Mg2+, 1 mM EGTA, and 1 mM dithiotreitol, with varying concentrations of [3H]5′-guanylylimidodiphosphate ([3H]Gpp(NH)p) (0.05–5.00 µM). Reactions were started by adding 50 µg of membrane protein and were terminated with 5 ml of ice-cold buffer containing 10 mM Tris hydrochloride, pH 7.4, and 100 mM NaCl, followed by rapid filtration through GF/C glass filters. The filters were subsequently washed twice with 3 ml of cold buffer and taken for scintillation counting. Agonist effects on [3H]Gpp(NH)p binding were assessed by adding isoproterenol (25 µM) or carbamylcholine (50 µM) to the reaction mixture. These are the minimum concentrations resulting in the maximum effect of the agonists. Nonspecific binding was determined by using 100 µM GTPγS and usually represented less than 30% of total binding.
On the day of assay, the membranes were thawed, 10-µg aliquots of membranes were taken for protein separation by gel electrophoresis with sodium dodecyl sulfate and 10% polyacrylamide, and the resulting proteins were transferred to nitrocellulose paper by use of an electroblotting apparatus. The blots were washed in Tris-buffered saline containing 3% polysorbate 20 and were blocked by incubation with 5% bovine serum albumin for 1 hour in Tris-buffered saline containing 0.1% polysorbate 20. After two washes in this solution, the blots were incubated overnight with each of the antisera (NEN-DuPont, Boston) directed specifically against Gsα (dilution 1:2,500), Gi1,2α (dilution 1:5,000), and Gβ (dilution 1:1,000) and were subsequently incubated with goat antirabbit IgG labeled with horseradish peroxidase. Immunoreactivity was detected with the Enhanced Chemiluminescence Western Blot Detection System (Amersham, Buckinghamshire, England) followed by exposure to X-ray film.
A preliminary assay of mononuclear leukocyte membranes from the healthy volunteers was carried out for determination of the range of linearity of the assay with respect to protein concentration. Linearity was found between 2.5 and 15.0 µg of membrane protein. Quantitation of the immunoblots was performed by densitometric scanning by means of an image analysis system. An aliquot of pooled standard membranes from rat brain cortex was run on one lane of every gel, and the immunolabeling was calculated in relation to this standard. This normalization procedure was carried out to minimize the between-blot variability. Although anti-Gsα detects both the 52- and 45-kDa Gsα species, only the 45-kDa species is consistently clearly detected in leukocytes, while rat cortex membranes show predominantly the 52-kDa species. The other subunits assayed in leukocytes were found to migrate at the expected molecular weights, similarly to those labeled in the rat cortex membranes.
Correlations of the functional and quantitative measures of G proteins in the mononuclear leukocytes of the depressed patients before ECT to those evaluated during the course of ECT were conducted by using the Spearman rank correlation. Differences in the agonist-induced increases in Gpp(NH)p binding capacity and the immunoreactivities of the various G protein subunits between the depressed patients before the initiation of ECT and the healthy volunteer group and between the depressed patients after completion of treatment and the healthy volunteers were determined through Bonferroni-corrected t tests for multiple comparisons of three groups by dividing alpha by 3. The results before and after ECT within the patient group were compared through paired t tests.
The G protein function in mononuclear leukocyte membranes was measured through increases in [3H]~Gpp(NH)p binding capacity induced by the β-adrenergic agonist isoproterenol or the muscarinic agonist carbamylcholine. Both agonists induced significant increases in Gpp(NH)p binding capacity without substantially affecting the affinity of binding. Isoproterenol-enhanced Gpp(NH)p binding capacity was specifically blockable by the β-adrenergic antagonist propranolol and by pretreatment with cholera toxin, with no effect of pertussis toxin, indicating a specific effect through Gs protein. Carbamylcholine effects on guanine nucleotide binding were specifically blockable by the M2 selective antagonist ADFX-116 and were exerted in a specific pertussis-toxin-sensitive manner, suggesting coupling with Gi protein (33).
As shown by Bonferroni t tests, in comparison with the age- and sex-matched healthy subjects, the patients with depression, while untreated, had statistically significant lower function of mononuclear leukocyte Gs (t=13.58, df=22, p<0.001) and Gi (t=11.05, df=22, p<0.001) proteins and significantly lower mononuclear leukocyte immunoreactivity of the Gsα (t=5.91, df=22, p<0.001) and Giα (t=12.50, df=22, p<0.001) subunit proteins. The immunoreactive levels of the Gβ subunit protein in the mononuclear leukocytes of the depressed patients and the healthy subjects were similar (T1).
The low Gs and Gi protein function (measured through isoproterenol- and carbamylcholine-enhanced Gpp(NH)p binding capacity) and immunoreactive measures in the mononuclear leukocytes of the untreated patients with depression were found to be normalized by ECT in a statistically significant manner, according to paired t tests (Gs function: t=11.20, df=9, p<0.001; Gi function: t=12.23, df=9, p<0.001; Gsα immunoreactivity: t=4.43, df=9, p<0.002; Giα immunoreactivity: t=4.86, df=9, p<0.001). The G protein measures after ECT were found to be not significantly different from those characterizing the group of healthy subjects, according to Bonferroni t tests (Gs function: t=0.24, df=22, n.s.; Gi function: t=1.56, df=22, n.s.; Gsα immunoreactivity: t=0.18, df=22, n.s.; Giα immunoreactivity: t=0.20, df=22, n.s.) (T1).
Repeated measurements of Gs and Gi protein function and of the immunoreactivity of the Gsα and Giα subunit proteins were conducted during the course of ECT in parallel with repeated clinical evaluations of depressive symptoms. F1 is a representative example of immunoblots obtained for the quantitation of Gsα and Giα proteins from mononuclear leukocytes of a patient with major depression undergoing ECT. The figure depicts normalization of the low Gsα and Giα immunoreactivity in the course of ECT. The detailed dynamics of normalization of the measures of G protein function (F2, top) and immunoreactivity (F2, bottom) in the mononuclear leukocytes of the depressed patients during the course of ECT in relation to the dynamics of clinical improvement reveal that the biological normalization preceded clinical improvement by at least a week.
There were significant positive correlations between the biochemical functional measures of G proteins, namely isoproterenol- and carbamylcholine-enhanced Gpp(NH)p binding capacity, and the respective immunoreactive measures of Gsα and Giα in the mononuclear leukocytes of the depressed patients undergoing ECT (Gsα: rs=0.76, N=38, p<0.001; Giα: rs=0.74, N=39, p<0.001). It can therefore be concluded that the dynamics of normalization of Gs and Gi protein function during ECT parallel the dynamics of normalization of Gsα and Giα immunoreactivity.
Our results show that the dynamics of normalization by ECT of the low function of Gs and Gi proteins parallels the dynamics of normalization of the low immunoreactivity of Gsα and Giα subunit proteins. The correlation between the function of Gs and Gi and their immunoreactive measures in mononuclear leukocytes of depressed patients at various stages of ECT supports a direct alteration at the G protein level. It can be concluded that the normalization of the low Gs and Gi function by ECT is related to a normalization of the low quantities of these proteins as shown by Gsα and Giα immunoreactivity.
The mechanisms underlying the alterations in G protein levels and function in mononuclear leukocytes of depressed patients and their normalization by ECT are still unknown. Increasing evidence indicates the existence of neurally mediated immunomodulatory mechanisms (34), involving the hypothalamic-pituitary axis and the sympathetic and parasympathetic innervation of primary and secondary lymphoid organs (35). Thus, alterations in mononuclear leukocyte G proteins may reflect 1) primary systemic alterations in G proteins similar to possible biochemical alterations in CNS signal transduction induced by the depressive episode and/or by ECT; 2) secondary influences of circulatory primary messengers, altered by the depressive state and/or by ECT; 3) secondary influences of altered sympathetic and parasympathetic innervation of lymphoid organs induced by the depressive state and/or by ECT. Most of the circulating lymphocytes are T cells whose lifespan is long: months or years (36). The lifespan of B cells is generally shorter: days or weeks (36). Both types of cells may have shorter transit times in the blood and tend to migrate to lymphoid organs. The majority of the long-living cells belong to a recirculating pool (36). Since repeated measurements of mononuclear leukocyte G proteins during a time period of around 3 weeks were conducted in the present study, it should be noted that the population of peripheral mononuclear leukocytes might be turning over or turning around through lymphoid organs throughout the course of ECT. Thus, the effects of depression and of ECT are probably exerted on the G proteins of cells in bone marrow and other lymphoid organs in addition to those in mononuclear leukocytes circulating in blood.
The differences in G protein measures between the depressed patients and the healthy subjects were not merely due to motor hyper- or hypoactivity, as normal subjects after intensive physical exercise (37) show G protein measures no different from the values for our healthy volunteer subjects. Also, G protein measures in the mononuclear leukocytes of elderly volunteer subjects, who in general are less physically active, did not differ from the measures in active, young subjects (38).
We are aware that the involvement of G proteins in the pathophysiology of depression and/or ECT, as implicated by the data presented here, should be considered cautiously, since extrapolations from findings obtained in blood cells peripheral to the CNS are not straightforward. We have discussed this issue in detail in a previous paper (8).
Our previous findings of high Gs and Gi protein function and Gsα and Giα immunoreactivity levels in mononuclear leukocytes of manic patients (5, 6) and of low Gs and Gi protein function and low Gsα and Giα immunoreactivity levels in unipolar and bipolar depressed patients (6–8) suggest that Gs and Gi protein quantitative and functional measures in mononuclear leukocytes are biochemical indicators of the affective state, rather than trait markers of bipolar mood disorder. Moreover, the function and quantity of both Gs and Gi were found to be significantly correlated with the severity of depressive symptoms (7, 8). The functional measurements of β-adrenergic-receptor-coupled Gs protein conducted in the present and previous studies are in accord with other functional findings of low β-adrenergic-coupled adenylate cyclase activity in patients with depression (39–43). In accord with the findings suggesting that the abnormalities in G protein measures in mononuclear leukocytes of mood-disordered patients should be considered state rather than trait markers, it should be noted that no structural or regulatory abnormalities in the gene for the G protein stimulatory α subunit were found in patients with bipolar disorder (44). Previous results have shown that the abnormalities in G protein functional measures are normalized by specific treatments: lithium-treated eu~thymic bipolar patients (5, 37) and antidepressant-treated mood-disordered patients (37) showed G protein function similar to that of control subjects, and those findings support the notion that alterations in G protein function in mononuclear leukocytes of affective disorder patients reflect their mood state. In this regard, the present findings showing low function and immunoreactivity of Gs and Gi proteins in unipolar depressed patients, and normalization of the function and immunoreactive levels of Gs and Gi proteins in the course of ECT, support the notion that mononuclear leukocyte G protein measures in mood disorders are state rather than trait markers.
The normalization by ECT of the biochemical measures of Gs and Gi function and of Gsα and Giα immunoreactivity levels did not follow, and thus reflect, the clinical improvement of the depressed patients. Rather, they preceded clinical improvement by at least a week. Gs and Gi protein functional and quantitative measurements in mononuclear leukocytes of patients with depression may thus potentially serve not only as a biochemical marker for the affective state of these patients but also as a biochemical means of predicting and evaluating response to ECT. It would be interesting to explore in the future whether psychotherapeutic intervention in depression can induce normalization of low G protein measures and, if so, whether the normalization of the biochemical measures precedes, as in the present study, or follows clinical improvement.
Received July 7, 1997; revision received Nov. 24, 1997; accepted Dec. 22, 1997. From the Departments of Clinical Pharmacology and Psychiatry, Faculty of Health Sciences, Ben-Gurion University of the Negev. Address reprint requests to Dr. Avissar, Department of Clinical Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 84105 Beer Sheva, Israel; email@example.com (e-mail). Supported in part by research grants from the Chief Scientist Office of the Israel Ministry of Health and by the Yadgarov Family Foundation to Dr. Schreiber and Dr. Avissar.
FIGURE 1. Immunoblots Obtained With Antisera Against Gsα and Giα Subunit Proteins in Mononuclear Leukocytes of a Patient With Major Depression After and Before Eight ECT Sessions, Compared With Normal Values
FIGURE 2. Rate of Normalization by ECT of Low G Protein Function and Immunoreactivity in Mononuclear Leukocytes of 10 Patients With Major Depression, Compared With Rate of Clinical Improvementa
aECT sessions were administered every 3 or 4 days over 3–4 weeks, for a total of eight sessions.
Download citation file:
Web of Science® Times Cited: 24


text:
If you've followed my blog or career for any length of time, you may have picked up on the fact that I LOVE sandwiches … and how I hardly mention them anymore. This is because back in March of this year, I was told I had a gluten sensitivity. Since then I've cut gluten out of my diet and my health has drastically improved (yay!). And while I have an occasional homemade sandwich on my favorite Udi's bread, it put quite the kabosh on my search for the perfect sandwich on the road (boo!).
Thankfully, more and more restaurants are catering to this allergy/intolerance/sensitivity. While I'm on the road with Ingrid Michaelson this summer, I've been using this really cool app called Find Me Gluten Free to search out restaurants and good food in each city. I'm going to blog a few of my favorites, because maybe it will benefit some of you travelers out there!
Pi Pizzeria is located directly across the street from The Pageant in St. Louis, MO. After the show, I met up with a few girlfriends and we walked over. I ordered a gluten-free pizza with sausage, peppers, fresh garlic and daiya cheese to-go from the bar. The staff were very friendly and chatted with us while we waited about 20 minutes for my pizza to be done. Usually #gf options tack on a few dollars, and this was the case. My small pizza was about $20, but WELL WORTH IT. Fresh ingredients, cooked perfectly. Some of my non-gf band mates had a slice and were surprised at how much they liked it as well. Thumbs up, Pi!
- quantumpsyche reblogged this from alliemoss
- teener likes this
- jeanssocool likes this
- forgetmealways likes this
- thedrawnshop likes this
- chickpeasandom likes this
- ibnmusic likes this
- fuffyberry likes this
- alliemoss posted this


text:
Last updated: Tue, Sep 3
Kaiser Health News consumer columnist Michelle Andrews writes: "If the volume of email from readers of this column is any indication, people are beginning to focus on how the health care overhaul will affect them. With the opening of the online health insurance marketplaces less than a month away, consumers with job-based coverage want to know if they can buy a plan there (answer: yes, but they may not qualify for subsidies); those with individual coverage want to know how the plans will compare with what they currently have (answer: generally better coverage and potentially higher premiums, offset by subsidies); and those who have been unable to afford a plan or turned down because they have medical problems want to know if the marketplaces will provide better options than they currently have" (Andrews, 9/3). Read the column.
This Story: Print | Link to | Top
Kaiser Health News staff writer Alvin Tran reports: "The federal health law's individual mandate, one of the key building blocks of the insurance overhaul, remains controversial as the October start date approaches for enrolling in new online marketplaces. Individuals who don't get insurance through work will shop for insurance on these websites for policies that will take effect in January. … Despite all that attention to the mandate, 26 percent of Americans aren't aware of the requirement or didn't think the law included it, according to a March 2013 Kaiser Family Foundation poll. Here are some basic questions and answers about mandate" (Tran, 9/3). Read the story.
Kaiser Health News staff writer Mary Agnes Carey reports: "In a move that the administration described as a 'blatant and shameful attempt to intimidate,' 15 Republican members of the House Energy and Commerce Committee are asking recipients of the $67 million in health law navigator grants to brief the panel on how they intend to spend the money" (Carey, 8/30). Read the story.
Now on Kaiser Health News' blog, The Seattle Times' Carol M. Ostrom, working in partnership with Kaiser Health News, reports: "With about 16 percent of its residents uninsured, Washington state falls solidly in middle of the pack, with Texas having the highest percentage of residents without health insurance: more than 25 percent. Massachusetts, where a state health-insurance mandate has been in place for years, has the smallest percentage of uninsured residents at just under 5 percent" (Ostrom, 9/3). Check out what else is on the blog.
Kaiser Health News provides a fresh take on health policy developments with "Unnecessary Roughness?" by Joe Heller.
Here's today's health policy haiku:
Raising debt ceiling
is a heavier lift with
health law funds in play.
If you have a health policy haiku to share, please send it to us at http://www.kaiserhealthnews.org/ContactUs.aspx and let us know if you want to include your name. Keep in mind that we give extra points if you link back to a KHN original story.
Sen. Ted Cruz, R-Texas, continues his battle to undo the health law, while a House Democrat from the deep South angers both sides of the political aisle. In other news, labor unions are frustrated the administration hasn't responded to their Obamacare concerns, while Republicans in tough re-election fights are wary of accepting big premium support to buy insurance in the exchanges.
Texas Tribune: Cruz Fighting An Uphill Battle To Defund Obamacare
On the statewide speaking circuit, U.S. Sen. Ted Cruz has made upending the federal Affordable Care Act sound simple: "The House of Representatives should pass a continuing resolution that funds the entire federal government, every bit of the federal government, except Obamacare," he told a group of Houston realtors last month (Rocha, 8/3).
The Associated Press: Barrow: Shutdown Threat Over Health Law 'Reckless'
In the past three years, Rep. John Barrow has outraged fellow Democrats with his vote against President Barack Obama's health care overhaul and been attacked by Republicans for refusing to support a full repeal. And the deep South's last white Democratic congressman is still defying both parties with his stance on the law. Before Congress adjourned Aug. 2, Barrow was among just four Democrats who sided with House Republicans voting to gut a key part of the Affordable Care Act that puts the Internal Revenue Service in charge of enforcing certain mandates (Bynum, 9/2).
Des Moines Register: Congress Preview: Rollout Of Health Care Reform
Even as major aspects of President Barack Obama's signature Affordable Care Act are set to take effect this fall and early next year, lawmakers continue to debate changes large and small. Dozens of conservative Republicans in Congress have proposed defunding the law entirely — and have hinted at shutting down the government if they don't get their way. Democrats and others, meanwhile, acknowledge small tweaks and fixes may be necessary as the law comes on line (Noble, 9/3).
The Hill: Labor Union Frustration Boils Over With President On ObamaCare
Unions are frustrated the Obama administration hasn't responded to their calls for changes to ObamaCare. Labor has watched with growing annoyance as the White House has backed ObamaCare changes in response to concerns from business groups, religious organizations and even lawmakers and their staffs (Bogardus, 9/2).
Fox News Union Dumps AFL-CIO For Its Positions On Obamacare, Immigration Reform
The International Longshore and Warehouse Union has cut ties with the AFL-CIO, citing in part the private-sector union's support for ObamaCare and immigration reform. In an August 29 letter to AFL-CIO President Richard Trumka, leaders of the 40,000-member union said they have become "increasingly frustrated" with the federation's policy positions on such matters as immigration and health care reform (Fox News, 09/03).
Meanwhile, health insurance coverage for Capitol Hill lawmakers and their staffs may become an issue on the campaign trail -
Politico: Obamacare Litmus: Lawmaker Perks
Leaders on Capitol Hill fought quietly behind the scenes for months to tweak Obamacare rules, so the government could keep making big premium payments for aides and lawmakers when they were pushed onto the new health care exchanges. But that victory is turning into something else for Republicans up for reelection and in tight primary races across the country: the latest Obamacare purity test (Sherman and Palmer, 8/31).
Minneapolis Star Tribune: Congress, Aides Prepare For Affordable Care Act
Congress faces a fast-approaching deadline for dealing firsthand with the requirements of President Obama's health care reform law. A wrinkle in the Affordable Care Act is taking away employee health care benefits from members, forcing the lawmakers and their aides to buy policies from state exchanges or make other arrangements starting Oct. 1 (Mitchell, 9/2).
And some other prickly questions persist -
Kaiser Health News: GOP Lawmakers Demand Information From Groups Getting Navigator Grants
In a move that the administration described as a 'blatant and shameful attempt to intimidate,' 15 Republican members of the House Energy and Commerce Committee are asking recipients of the $67 million in health law navigator grants to brief the panel on how they intend to spend the money (Carey, 8/30).
The Washington Post: Signing People Up For Obamacare? House Republicans Have Some Questions For You
The navigators have become, as of late, a flashpoint in the Obamacare debate. More than a dozen states, my colleague Sandhya Somashekhar reported this week, have put restrictions on the work that these guides can perform. ... Health and Human Services described the letter as a "shameful attempt" to intimidate groups doing Obamacare enrollment (Kliff, 8/30).
Three states plan to open call centers today to aid consumers in finding their way around new health exchanges, slated to start business on Oct. 1. Meanwhile, in Alaska, federal officials and local organizations are working to try to get a marketplace up and running before this deadline, and California's marketplace offers more details about premium rates for coverage that will be available.
USA Today: State Health Care Call Centers Ramp Up For Oct. 1
Vermont has 45,000 uninsured residents that it's trying to attract to its new health insurance exchange. Connecticut has 344,000. Washington state is targeting 1 million people without insurance. The three states, each with its own-sized challenge, will open call centers Tuesday to help as many of these people as they can navigate a new federally mandated way to buy insurance starting Oct. 1 (O'Donnell, 9/2).
The Associated Press: Alaska Facing Deadline Without Insurance Exchange
Federal officials and Alaska nonprofits are scrambling to establish a health insurance marketplace by the Oct. 1 deadline required under the federal Affordable Care Act. Alaska is among 27 states that have refused to set up marketplaces, also known as exchanges, where the uninsured can shop for coverage (9/2).
Los Angeles Times: California Gives Consumers Detailed Rates Under Healthcare Overhaul
Californians can now see specific rates from competing health plans on a new state-run insurance market set to open Oct. 1. Covered California, the new state marketplace, launched an online feature Thursday enabling consumers to get detailed price comparisons for their area for the first time (Terhune, 8/30).
USA Today reports that a coalition of providers and insurers are actively promoting the online insurance marketplaces in states that have opted against running their own health exchange. Meanwhile, The New York Times examines how some insurance companies are advertising the new insurance system.
USA Today: Health Care Providers, Insurers Pitch State Exchanges
A coalition of health care providers, insurers, bill collectors and community groups have stepped in to promote exchanges where people can buy health insurance even in the states that have declined to create or promote their exchanges (Kennedy, 9/2).
The New York Times: With Change Coming, Aetna Targets Employers
As the country marches toward a new health insurance system, insurance companies have spent millions on consumer advertising to position themselves as health care companies (Vega, 9/2).
The Washington Post: These Two Maps Are Incredibly Important To Obamacare
If you want to understand where Obamacare stands to have the most significant impact, check out these new maps from the Census. They show uninsured levels for every county in the United States, broken down by income level: ... these maps explain why you see a group like Enroll America focusing its work on 10 states, rather than sweeping out across the country (Kliff, 9/1).
The Wall Street Journal: Obamacare, But By Any Other Name
At the Minnesota State Fair, state employees are promoting a health-insurance marketplace called MNsure by handing out fans imprinted with pictures of Paul Bunyan and Babe the Blue Ox. ... Minnesota, along with thirteen other states and Washington, D.C. that are fully running their own health-insurance marketplaces, is marketing this way because it believes it will draw customers, even if it doesn't change popular impressions of Obamacare, the health overhaul designed to provide coverage to those who don't have it from their employer or elsewhere (Corbett Dooren, 8/30).
Earlier, related KHN story: States Use Out-Of-The-Box Approaches To Raise Awareness Of Health Exchanges (Miller, 8/21).
Economist says half of the rural poor who would be aided by expansion live in states that have opted not to take that step.
The Associated Press: Economist: Medicaid Expansion A Rural Issue
Rural residents will likely benefit from the health care overhaul, but many will be hurt by their states' refusal to expand Medicaid coverage, a health economist said during a recent conference on rural health care. ... He told hospital administrators and others gathered in Milwaukee that when researchers look at rural residents who could be covered by expanded Medicaid, more than half live in states that have opted out. In comparison, more than half of the urban residents eligible for coverage under the expansion live in states that are going forward with it (Johnson, 8/2).
News outlets also looked at the issue of expansion as it plays out in several states.
Dallas Morning News: Study Says Texas Premiums Will Rise With Medicaid Expansion Opposition
Texas' refusal to expand Medicaid will cause private health insurance premiums to rise by an average of 9.3 percent for people who buy their own coverage, a new study finds. GOP lawmakers, strongly encouraged by Gov. Rick Perry, decided not to add poor adults to Medicaid's rolls. That means about 1.3 million fewer Texans will have health coverage by 2016 than if the federal Affordable Care Act were fully implemented in the state, according to the study by the nonprofit research organization Rand Corp. (Garrett, 9/2).
The Columbus Dispatch: Group Gathering Signatures For Medicaid Expansion Ballot Initiative
Frustrated with GOP leaders refusal to act on [Ohio] Gov. John Kasich's proposed Medicaid expansion, advocates for the uninsured have begun collecting signatures which could send the issue to the ballot for voters to decide. The effort is being led by a broad-based coalition made up of businesses, unions, health-care providers religious organizations, consumer groups and advocates for the uninsured (Candisky, 8/31).
The Associated Press: Medicaid Debate Turns To When Expansion Occurs
The Michigan Senate's intense, months-long debate over Medicaid expansion and the federal health care law is not over, even after the Republican-controlled chamber's milestone vote to provide health insurance to hundreds of thousands of low-income residents. Senators on Tuesday will reconsider the issue of when the legislation should take effect (Eggert, 9/1).
Detroit Free Press: Michigan's Medicaid Expansion A Relief For Hospitals Giving Unpaid Care
Hospitals administrators across the state are hopeful that since the Medicaid expansion bill cleared its biggest hurdle last week, they can recoup some of the hundreds of millions of dollars they lose each year providing uncompensated health care to poor and uninsured patients. ... several of the systems that serve large numbers of low-income patients, including Henry Ford Health System and St. John Providence Health System, estimated they will save roughly 10 to 15 percent on the amounts they lose each year to uncompensated care — free charity care, unpaid patient bills and services provided to uninsured people at reduced prices (Reindl, 9/2).
Meanwhile, one outlet looks at changes coming in Michigan with the new online health marketplaces -
Detroit Free Press: Companies And Organizers Prep For Michigan Exchange Rollout Oct. 1
Nearly every Michigander will have access to basic health insurance — and be required to get it — beginning Oct. 1 as federal health reform's largest provisions start snapping into place with the launch of each state's Health Insurance Marketplace. For those with no insurance or bare-bones coverage, that could mean more generous benefits than they've ever had, once coverage becomes effective Jan. 1 (Erb, 9/1).
News outlets report on how the law might affect clinics serving the poor, concerns about scams and details about how the individual mandate will work.
California Health Report: ACA Brings Opportunities, Challenges To Clinics Serving The Poor
With all Americans required to enroll in health insurance under the Affordable Care Act, will the existing safety net clinics become a thing of the past? For generations, grassroots-style community clinics have worked to fill the coverage gap; their mandate, to treat any patient who walks in the door, regardless of ability to pay (Bartos, 9/3).
The Philadelphia Inquirer: Beware Of Health-Insurance Scams Under ACA
Confused is the word many Americans are using to describe the Affordable Care Act…"Confusion is a crook's best friend," said James Quiggle, communications director at the Coalition Against Insurance Fraud in Washington. In ACA fraud, the key objective is your medical record (9/1).
Kaiser Health News: FAQ: How Will The Individual Mandate Work?
The federal health law's individual mandate, one of the key building blocks of the insurance overhaul, remains controversial as the October start date approaches for enrolling in new online marketplaces. Individuals who don't get insurance through work will shop for insurance on these websites for policies that will take effect in January. … Despite all that attention to the mandate, 26 percent of Americans aren't aware of the requirement or didn't think the law included it, according to a March 2013 Kaiser Family Foundation poll. Here are some basic questions and answers about mandate (Tran, 9/3).
A statewide transitional care program in North Carolina may hold hope for reducing hospital readmissions in the U.S., a new study finds. In the meantime, readmissions' financial stakes become clear for one Minnesota hospital.
Reuters: Hospital To Home Focus May Reduce Readmissions: Study
Helping people who were recently released from a hospital understand how to care for themselves and informing their primary care doctors about their stay may reduce their risk of being admitted back into the hospital, says a new study. Researchers found that implementing a statewide transitional care program for North Carolinians on Medicaid -- the state and federal insurance for the poor -- was linked to a 20 percent reduction in patients' risk of going back to the hospital during the next year (Seaman, 9/2).
Pioneer Press: Re-admissions Prove Costly For Minnesota, U.S. Hospitals
As hospitals across the country struggle to prevent patient re-admissions, the stakes in Minnesota are clearest at Fairmont Medical Center -- a small hospital just north of the Iowa border that has received low marks on a federal report card for two consecutive years. … The efforts have been spurred, in part, by the federal health care overhaul of 2010, which created the Medicare penalty program. Private health insurers also have pushed hospitals to help prevent re-admissions when possible (Snowbeck, 9/2).
News outlets examine what options nursing home patients have when their Medicare benefits run out and the latest challenge to reforming how doctors are paid by the program -- the price tag.
The Philadelphia Inquirer: When Medicare Runs Out For Nursing-Home Patients
Mary-Carol Feeney's Medicare coverage was running out, and in mid-February, her nursing home in Montgomery County told her she would have to leave. … Medicare -- public insurance for the elderly and disabled -- covers most of the costs of skilled nursing for up to 100 days after a hospital stay. But many patients do not realize that, when Medicare coverage stops, they have other options -- because, advocates say, the facilities fail to inform them (Skinner, 9/1).
Medpage Today: Paying For SGR Fix Proving A Challenge
The price tag for a bill to repeal and replace Medicare's sustainable growth rate (SGR) payment formula could cost significantly more than just repealing it, congressional staffers said. Lawmakers have worked with greater tenacity this year to repeal the SGR, in part because of a lower price to repeal the formula, which has drawn broad disdain. The Congressional Budget Office (CBO) said earlier this year it would cost $138 billion -- more than $100 billion less than it had estimated in years prior -- to do away with the system (Pittman, 8/30).
News outlets covered various studies about health costs and doctor earnings.
Bloomberg: Pay Gap For Women Doctors Increases To $50,000 A Year
Female physicians in the U.S. continue to earn less than their male counterparts, with the pay gap widening during the past two decades to more than $50,000 annually in 2010, researchers said. Women doctors had a median annual income of $165,278 from 2006 to 2010, compared with yearly earnings of $221,297 for male physicians, according to the report published today in JAMA Internal Medicine (Cortez, 9/2).
The Washington Post: Large Employers Project An Increase In Health Care Benefit Costs In 2014
Large employers expect their cost of health care benefits to rise 7 percent in 2014, according to annual survey conducted by the National Business Group on Health, a nonprofit whose members include 66 Fortune 100 companies (Halzack, 9/1).
Earlier, related KHN story: Survey: Big Business May Shift Retirees, Part-Timers To Insurance Exchanges(Hancock, 8/28)
The Philadelphia Inquirer: Check Up: Prescription-Discount Coupons Have Hidden Costs
Instant savings! Free 30-day trial voucher! Pay no more than $18 a month! These are the kinds of alluring phrases you can find on coupons for brand-name prescription drugs. But an article in the New England Journal of Medicine warns that behind such catchy language, there is a catch: You likely will not save money in the long run (Avril, 9/1).
A selection of health policy stories from California, Ohio, Mississippi and Washington.
Los Angeles Times: State Bill To Boost Use Of Nurse Practitioners Goes Nowhere
An effort to ease a shortage of primary-care doctors in some California communities by letting nurse practitioners operate more independently has flat-lined in the Legislature after a fierce lobbying battle. A bill by Sen. Ed Hernandez (D-West Covina) would have allowed nurse practitioners, who have more training than registered nurses, to practice without the direct supervision of a physician (Mason, 9/1).
Columbus Dispatch: Nonprofit Senior-Housing Developer Turns Focus To Health Care
An Upper Arlington company that is the nation's largest nonprofit provider of affordable housing for senior citizens is poised to continue its model of offering medical care and other services to people where they live. National Church Residences, or NCR, provides health care at dozens of its Ohio locations. Along with continuing-care retirement campuses, assisted-living centers, nursing homes, home health care and hospice, the company also has on-site primary-care services at a number of residences and offers health care at adult day-care centers (Viviano, 9/3).
The Associated Press: Analysis: PEER Proposes Review Of Trauma Care Cost
Two incidents that occurred within months of each other prompted Mississippi public health leaders and lawmakers to invest in a trauma care system. On Nov. 5, 1995, Gov. Kirk Fordice was severely injured when his sport utility vehicle ran off Interstate 55 north of Grenada and flipped over. He was transferred to the University of Mississippi Medical Center in Jackson, the state's only Level I trauma center (Elliot, 9/1).
Kaiser Health News: Capsules: Washington Ranks 2nd In Nation In Uninsured Growth
With about 16 percent of its residents uninsured, Washington state falls solidly in middle of the pack, with Texas having the highest percentage of residents without health insurance: more than 25 percent. Massachusetts, where a state health-insurance mandate has been in place for years, has the smallest percentage of uninsured residents at just under 5 percent (Ostrom, 9/3).
USA Today: Debt Limit Politics: Our View
As was the case during the last debt-ceiling debacle, in 2011, playing politics with the nation's creditworthiness is irresponsible and unnecessary. Leave aside the ObamaCare obsession, because Republicans have zero chance of persuading the president to kill one of his defining achievements. After defeats in Congress, the Supreme Court and last year's presidential election, the ObamaCare opponents seem like the holdout Japanese soldiers who kept fighting World War II into the 1970s (9/2).
USA Today: Tie Debt Limit To Spending Cuts
There is no need for market-rattling showdowns or brinksmanship in the discussion this fall. The sooner President Obama starts to work with both parties to solve Washington's spending problem, the better it will be for our economy (House Speaker John Boehner, R-Ohio, 9/2).
The Washington Post: Republicans Should Get Out Of The Way Of Obamacare
Congress enacted the Affordable Care Act. The Supreme Court found most of its provisions to be constitutional. Republicans, having opposed the bill and supported the legal challenge to it, are entitled to be unhappy about the outcome, though in our view they are wrong on the merits. They are not entitled to obstruct and flout the laws of the United States. On the contrary, they have an obligation to cooperate in good faith with wholly legitimate laws duly passed and reviewed by all three branches of government (9/2).
The Washington Post: In Budget Fight, GOP Doesn't Act In The National Interest
Do [Republicans] really believe the president is willing to forsake his most important legislative accomplishment? Before it even comes fully into effect? This is a tragic waste of time and effort. Remember when Democrats captured the House in 2006? They worked with George W. Bush even though they disagreed with his policies (Eugene Robinson, 9/2).
The New York Times: How A Cabal Keeps Generics Scarce
About a year ago, President Obama signed a law that was supposed to end chronic shortages of lifesaving drugs. But the critical lack of generic drugs continues unabated. It is a preventable crisis that is inflicting suffering on patients and, in some cases, causing needless deaths (Margaret Clapp, Dr. Michael A. Rie and Phillip L. Zweig, 9/2).
The New York Times: Doctors And Their Medicare Patients
Critics who want radical changes in Medicare, the public insurance program for the elderly and disabled, often allege that the program is heading for disaster because stingy payments from the government are causing a rising number of doctors to refuse to serve Medicare patients. ... Those concerns have always been greatly exaggerated. Now a new analysis by experts at the Department of Health and Human Services should demolish that mythology for good (8/31).
Bloomberg: Health Savings Accounts As Antidote To Obamacare
For years, conservative health-policy analysts have highlighted the power of consumer-directed arrangements such as health savings accounts to restrain costs, help consumers gain more control over their medical decisions and improve the quality of care. Yet Obamacare, as well as some state policies, are undermining the effectiveness of HSAs. Republicans now have an opportunity to rally around reforms to replace Obamacare and address health-care spending. Making HSAs more attractive and widely available is an important piece of the puzzle (Lanhee Chen, 9/2).
Arizona Republic: Affordable Care Act Needs Fixes To Address Costs
TI've heard from families and businesses concerned about the lack of specific information regarding implementation of the ACA, what the law means for them and and what the marketplace costs and options will be. This frustrating lack of information from the federal government is hampering their ability to plan for the future. My staff and I are working to help businesses and families navigate the current law (Rep. Krysten Sinema, D-Ariz., 9/1).
Bloomberg: Free Nurse Practitioners From Supervision
Whatever its flaws, the Patient Protection and Affordable Care Act has sparked innovation across the U.S.'s sclerotic health-care system. An especially welcome example is the push to expand the role of nurse practitioners in primary care. The country's 171,000 NPs are trained to do many jobs that primary-care doctors do: diagnose problems and treat patients, order tests, prescribe drugs and refer to specialists. And with an average income of $99,000, they're a bargain (8/30).
The Philadelphia Inquirer: The Philadelphia Inquirer: Too Poor For A Health Premium Subsidy
Will low-income Pennsylvanians be tempted to overstate their income to the IRS in order to afford health insurance? The state's rejection of Medicaid expansion for its poorest citizens creates this perverse incentive (Michael Campbell, 9/1).
Detroit News: Has Snyder's Medicaid Expansion Mortgaged Michigan's Future?
The Michigan Legislature's bipartisan approval of [Gov. Rick] Snyder's expansion of Medicaid coverage to 133 percent of the poverty line last week was a rational decision given Obamacare's threat to small businesses and the federal government's promise to cover near-term expenses . ... The Medicaid deal is a short-term solution that, like Detroit's past largesse, puts the state at long-term risk well after Snyder & Co. have left office (Henry Payne, 9/3).
St. Louis Post-Dispatch: Costs Of Not Expanding Medicaid In Missouri Begin To Hit Home
There are Republicans in Missouri who argue that the nearly 800,000 people in this state without health insurance already have access to the health-care system. They are not entirely wrong. Anyone who can get to a hospital emergency room can be seen by a doctor. If you have no means to pay, your care might even be free. But somebody always pays (9/3).
St. Louis Dispatch: Three Reasons Why Missouri Should Expand Medicaid
Since July, the Interim Committee on Citizens and Legislators Working Group on Medicaid Eligibility and Reform has listened to testimony across Missouri. Consensus exists about ways to build on the successes of the current Medicaid program, and about some areas in which reform is needed. But these are complex issues. Missouri cannot afford to delay expanded eligibility until reforms are implemented. The opportunity to save lives and give peace of mind to more 250,000 Missourians will have passed (Ruth Roetheli Ehresman, 9/3).
Minneapolis Star Tribune: Health Care: A Roadblock To Entrepreneurial Ambition
This means that entrepreneurialism in America, the Land of Opportunity, is becoming solely the province of the young, rich, healthy and illogical. By tying health insurance to full-time employment, we have made entrepreneurialism devastatingly unlikely, because even those who could afford to live on, say, a 25-hour workweek must also forfeit affordable insurance. The solution here certainly doesn't have to be state-run health care, and it really doesn't even have to include state-sponsored health insurance (Andrew Finken, 9/2).
The Philadelphia Inquirer: To Implement Obamacare, Start By Explaining It
Beginning next year, you will have to maintain coverage of some sort if you can afford it, but you are guaranteed that it will be available. A simple message like this could go a long way toward reducing the confusion. It might lead many of those who disapprove of Obamacare to withhold some of their skepticism. And the task of implementing the law would become a whole lot easier (Robert Field, 9/2).
Stephanie Stapleton
Andrew Villegas
Lisa Gillespie
Shefali Luthra
The Kaiser Daily Health Policy Report is published by Kaiser Health News, an editorially independent program of the Kaiser Family Foundation. (c) 2014 Kaiser Health News. All rights reserved.
© 2014 Henry J. Kaiser Family Foundation. All rights reserved.


text:
I think I want to go to Iceland on vacation.
Give me your Iceland thoughts!
Who's been? When should I go? Where should I go?
I think I want to go to Iceland on vacation.
Give me your Iceland thoughts!
Who's been? When should I go? Where should I go?
Natural Swimming Holes Around the World | Adriatic Sea, Roca Vecchia, Italy
National Park Views Not to Be Missed | Yellowstone National Park
Condé Nast Traveler Photographs: 25th Anniversary Collection | Katikies Hotel, Santorini, Greece
Castillo Wulf, Valparaiso, Chile
What a way to spend a weekend—at a royal wedding. Here's our full album of exclusive Bhutan wedding photos, taken by Jered Barclay for Condé Nast Traveler.
(Source: condenasttraveler)
Some great images of my favorite city - Valparaiso, Chile.
(via tasyamenaker)
"They are here, but they are not here. There are some identifying fragments, physical evidence of their culture and social refinement. But what kind of connection can you make with a people who have been gone for two thousand years? I am looking for the Romans in England."—Clive Irving explores the baths of old Blighty.
Photo (Bath, England): Andrew Moore
(Source: condenasttraveler)
VaLpAraíSo (by urbaguilera)
smile in mountain by phitar on Flickr.
(Source: kokohe)
Every year Santa Fe stuffs all their wishes and troubles into a huge bogeyman marionette called Zozobra. Then they burn him down in a glorious blaze of pyrotechnics and fireworks putting all their troubles behind them
Zozobra!! ¡VIVA LA FIESTAAAAAAA!
Take that, emotional baggage.
Cassettes. Remember them?
What's on your travel playlist?
My podcast yesterday said that Cassette has been removed from this year's edition of the dictionary. Replaced with "sexting" and "woot."
(via condenasttraveler)
(Source: animalesdepaseo)


text:
Welcome to my personal blog.
I'm Sketch, also known as PaperNightjar. I enjoy illustrating and gaming, among other things.Anything that catches my interest goes here.
OC concept thingy I think…:O
She doesn't exactly have a name yet (seems to be a trend with my OCs B'D) but she suffers from a condition similar to the werewolf curse, though hers is more like a malignant mutation caused by contact with already afflicted cells :'3 (it tranfers in a similar method to the werewolf curse, but blood on blood contact must occur)
In short, the mutation has caused her own blood to turn silver, and on the nights of new moons she transforms into a Wendgio like monster, and must be trapped to prevent her hurting herself.
She has a scar on her face from one episode in which she managed to escape capitivity, and ended up fighting with a brown bear, which she subsequently mauled. (I have nothing against bear btw!! 8'D)
She also has a scar on her back, from when she first contracted the mutation. ;<;


text:
View all questions by zahirhussain
Answered On : Oct 4th, 2006
Insert the record/data from Applicaiton then open related database table(Sql Server/Oracle) and verify data stored properly, which u have entered through application. (In SRS, clearly they mention abt Database tables and on which table the screen information should store) Internal Quality Audits means, QA people conduct audits internally to measure the company process. QA people conduct audits --> HR, Projects,QA, Purchases, Network.. Departments. (Ex: IQA is just like quterly examinations, based on QA feed back all department imporves there process. External Quality Audit means it will conduct every approx 9 months)
Answered On : Oct 23rd, 2006
Negative Testing a Database :As the normal meaning of the negative testing is to give some input which is not appropriate(wrong input) to test whether the system shoots out the warning or not. Same way while you are testing the database you, you need to have sample data( which is already stored in database) Ex: username and password for a login screenwhen you try to give a username and password which are not valid and relavent then the system has to check with the values that are stored and has to show a mismatch. If it shoots out or pops up or displays a message of this irrelavence occurance then we can be sure that the system is passing in negative test.Qulaity AuditQuality audit is normally conducted by QA people to find out the level to which the standards have been attained. Depending on this result the analysis of the quality that is followed to develop a process can be calculated. I always keep it like this "All the rivers have humble begning", so is the case with the quality. It may not look like the serious thing in the beggining but by the end it will have a great impact on the outcome. so internal quality auditing is necessary to keep track of the quality process attained.
Answered On : Mar 12th, 2007
We can do negative testing for Database:In a login window we can pass unexpected data in the user name and password.Mainly like blind SQL injection or LDAP injection.Regards:Naveen Pathak
Answered On : Jul 6th, 2007
View all answers by idreams27
For internal Audits.Internal Quality Audit is related to the process that you are following within an organization. It may include how the projects are assessing the quality based on the process the company has.It might be ISO audit or CMM assessment. They once again pertain to how the process is followed at business unit level or at individual project level.If you take one project for which we need to do a CMM assessment or Quality Audit. First they will look into the various phases of the project and verifies each pahse at CMM level or qulaity level it will fall. This will be carried out based on the guidelines and checklists available in the organization process. For example: Take various phases like 1. Requirements Phase2. Design Phase3. Coding Phase4. Testing Phase. All these phases each will be verified at what level(like CMM level1/2/3/4/5) they fall. If they are not in the expected level then they work on the strategies to be followed to make them improve to reach to expected levels.Usually internal audits can be carried out in an organization for every quarter once. This audits will help you in finding the loop holes and gaps following in the current process and helps them to refine them accordingly. Also these audits will help you or give confident level for external audits.Generally when your are going for external audits or certifications they will consider the whole company process for the audit based on few picked projects from various business units(if the company has) and verify them towards their standards. If it is goes fine then the company will be certified with the CMM assessment or ISO standard.Hope i have answered your Questions.For any more clarifications you can reach me at idreams27 AT yahoo DOT comThanksNarasimha
If you think the above answer is not correct, Please select a reason and add your answer below.
.Net Testing
Bug Tracking
DataBase Testing
Functional Testing
Load Testing
Mobile Testing
Network Testing
Product Testing
QA Testing
Quality Control
Quality Management
Security Testing
Software Testing
Test Automation
Test Cases
Testing Basics
Testing Definitions
Testing General
Testing Scenarios
Web Testing
Whitebox Testing
Wireless Testing
What are my options when I do not get a job after graduation?
What is your way of building rapport with a person you just met?
How do you handle workplace problems?
How do you approach a problem?
Careers and Higher Education Options for BBA Graduates
How to handle academic gap while applying for a job?
Provide an example of a goal that you successfully attained.
Aptitude Test Preparation Tips
Do you find yourself busy most of the time? Why?
Do you like working in a team or alone? Explain.
Ask Interview Question?
Get invaluable Interview and Career Tips delivered directly to your inbox. Get your news alert set up today, Once you confirm your Email subscription, you will be able to download Job Inteview Questions Ebook . Please contact me if you there is any issue with the download.