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As a partner at Kleiner Perkins Caufield & Byers, Dana Mead supports entrepreneurs and innovators seeking to make major impact through life science technologies and ventures. In this lecture, Mead talks about Venture Capital, offering great insights about Silicon Valley and life as a venture capitalist.
Want to get connected? Sign up to receive regular news, polls and updates from The Kauffman Foundation.

subset: commoncrawl


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The Twitter business idea pitch, also known as a "biztweet," "twitpitch" or "twitch," has arrived. Yes, that means entrepreneurs have 140 characters, tops, to explain their start-up ideas — making the classic elevator pitch, which can take a couple of minutes (sometimes in an actual elevator, as with Wake Forest University's annual event), feel downright dilatory.
It took business plan competition organizers some time to embrace the brevity-requiring, social media platform of Twitter in the first place. Twitter made its debut in 2006, but it was only this year that most of the institutions aiming to inspire, educate and support entrepreneurs with business competitions got on it officially.
Most of these institutions, like Babson College (@babson), the New York Public Library (@nypl) and Alibaba.com (@alibabatalk), have an official profile on Twitter, from which they publish general news of their organizations and, intermittently, of their competitions.


text:
What will your children do this summer that will have a positive impact on their souls? What eternally important activities will they be involved in? Will they spend their summer glued to televisions, iPads, video games, and cell phones, or will they take the time to "grow in the grace and knowledge" of God?
Why not encourage your children and the youth of your local congregation to seize the summer and attend one of Apologetics Press' soul-strengthening Christian Evidences summer camps, as they fellowship with Christians from around the country?
"Defending the Reliability of the Bible"
June 10-15 (Indian Creek Youth Camp)
"The Existence of God"
June 24-29 (Backwoods Christian Camp)
I will be directing the June 10-15 week of camp at Indian Creek Youth Camp (ICYC) in Oakman, Alabama (approximately 40 miles northwest of Birmingham). Ben Thompson of Meridianville, Alabama will direct the June 24-29 week of camp at Backwoods Christian Camp (BCC) in Lineville, AL (approximately 80 miles east of Birmingham). Ben is a long-time youth director and is heavily involved in foreign missions. [NOTE: Although A.P. is not directing this week of camp, we are providing the teachers and speakers each day during the class time, as well as for the nightly lectures.]
Teachers for these two weeks of camp include Kyle Butt, Dave Miller, Jeff Miller, and myself. Some of the speakers for the second week of camp (on "The Existence of God") will be A.P. scientists, including Dr. Jeff Miller (biomechanical engineer), Dr. Joe Deweese (biochemist), Dr. Jerry Fausz (aerospace engineer), and Dr. Mike Houts (nuclear engineer).
Some of those teaching the younger-age classes include A.P. support staff members such as Rob Baker and Rhonda Thompson, as well as a few preachers and youth directors that are close friends and supporters of the work at A.P.
The camps are for 3rd-12th graders. The week at ICYC (June 10-15) costs $135 each. (All checks are to be made to ICYC.) You can register your children on-line at www.icycal.com, or you can print an application from their Web site and mail it to them.
The A.P. week at Backwoods costs $120. (All checks are to be made to BCC). You can register your children for this week by going to http://backwoodschristiancamp.org/wordpress/2011-schedule/, printing off an application, and mailing it to them.
With the Lord's blessings, we expect these weeks of camp to fill to capacity. (The camp sites will hold approximately 200 campers each.) Registration is first come, first serve. If you would like to know more about A.P.'s summer camps, please call 334-272-8558.


text:
Sunday, 23 January 2011
Judith Potts is at it again
55 comments:
"Her ignorance is astounding" - yes, that seems to be the bottom line.
First of all JP sets up an unfortunate dichotomy between palliative care nurses and those working in acute hospital settings - and with it a failure to understand the significance of context (political as well as clinical).
For example, she seems oblivious to a recent report
from the Royal College of Physicians which found "access to palliative care services is inadequate and inequitable, with unacceptable variations in care geographically, across different demographic groups and patients with different illnesses and needs. There is particular disparity between patients with cancer and those suffering from non-malignant conditions. The best care is excellent, the worst may be non-existent".
So is JP content for some dying patients to receive excellent palliative care while others presumably don't?
She is also wrong to say that hospices are funded by charity, which in her mind creates a quality imperative - the split is more like 70-30 (almost a third of the cost of hospice care comes from the public purse just like the rest of the NHS).
I'm sure somebody with more time and energy will Fisk JP's article point by point but as already noted the level of ignorance is actually breath taking.
- 23 January 2011 13:42
- Nurse Anne said...
Its funny but scary at the same time.
Usually these kinds of articles make me angry.
But this one actually had me laugh at loud.
- 23 January 2011 13:45
LMAO, I love how they brought up your article in the guardian down at the comments. Anne you dirty imposter you!!
I have been at loggerheads with that dickhead lightf00t for most of the weekend in another telegraph claptrap article. He hops from article to article spewing his filth. He's not a student nurse, he's an idiot.
- 23 January 2011 17:31
- Nurse Anne said...
LightF00t is classic. I hope no one gets offended by my bursery comment. If I was training right now in the UK I would have to do a bursery. I am just lucky that in the time and place that I trained it was an easier world.
- 23 January 2011 17:40
I am all over those comments right now to be honest and no I didn't get offended by your comments as I indicated. My bursary is more of a hindrance than a help.
- 23 January 2011 17:44
I am the most patient person you will ever meet in your entire life should you ever have the misfortune to ever meet me ofcourse.
I am however, for the first time, about to lose my nut on the internet via that link. I know I shoulden't get so invested in the idiots but I can't help it tonight. Something about one or two of those commenters makes me wanna lash out into a fit or rage.
If I don't come back for a while it's because I smashed my computer up.
- 23 January 2011 18:47
- Nurse Anne said...
God the comments on there are all out of chronological order. Pain in the arse.
- 24 January 2011 03:06
I don't give two tits if Judith Potts is a cancer survivor. She doesn't know a damn thing about Nursing in the NHS.
- 24 January 2011 05:14
- Nurse Anne said...
I wonder what made her think that hospice nurses are trained differently than NHS ward nurses?
- 24 January 2011 08:07
She probably went to google or the UCAS website and found a Bsc in Palliative Care (the top-up) and thought that must be it.
She certainly hasn't done the proper research, to say the least.
But what do you expect from a "journalist" in a background in acting.
- 24 January 2011 10:00
- Dino-nurse said...
Lost the will to comment after reading her previous articles
1) The Telegraph caters to the twinset and pearls brigade, so they are always "shocked" and "appalled"
2) Actress as a journalist?...lol...I googled her and couldn't find any listing of where/when she acted in anything
3) In a few years such people will get what they think they want, as the NHS disintegrates....by that stage they will be chronic medical patients and will no longer qualify for treatment....be careful what you wish for
- 26 January 2011 05:44
- little dumpling said...
As a fairly frequent patient in NHS hospitals I have to say that the care I and a few others I know have received has always been of high standard. The best care IS excellent, but the NHS does need more nurses on the wards as they are spread far too thinly. These people are frequently run off their feet, but such is their dedication they won't let their patients down. Yes, there are a few who are a little work shy, but thankfully their numbers are small. In my Mothers days as a Nurse she was once refused permission to go'off'duty as the Ward Sister remarked that she had not completed her work adequately, Two hours later, my darling little Mum learned that one of the castors on a bed was crooked, "thus Nurse, you would have left a sloppy ward!"!
With reference to the report from the Royal College of Physicians about disparity of care between patients with cancer and those with non-malignant conditions, and I don't really know if this information is significant here, but two days ago I actually found a website that appears to offer help for mind and body discomforts-including something for after cancer treatments and depression, whether this site would be useful to folk with 'non-malignant' conditions I've no idea but I thought I'd mention it.
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CSI: Crime Scene Investigation - Season 3 DVD
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- Additional Details
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- Number of Discs: 6
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Last updated 10-6-2014
Cubs 40-Man Roster Info
Organization Depth Chart
MLB Rules Info
40 players on RESERVE LIST (roster is full), plus three players on 60-DAY DL
* bats or throws left
# bats both
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Pedro Strop
Jacob Turner
Carlos Villanueva
Arodys Vizcaino
* Tsuyoshi Wada
* Travis Wood
* Wesley Wright
* John Baker
Welington Castillo
* Rafael Lopez
Javy Baez
Starlin Castro
Mike Olt
* Anthony Rizzo
Chris Valaika
* Luis Valbuena
Christian Villanueva
* Logan Watkins
# Arismendy Alcantara
* Chris Coghlan
* Ryan Kalish
Junior Lake
Jorge Soler
Matt Szczur
Josh Vitters
James McDonald, P
Justin Ruggiano, OF
* Ryan Sweeney, OF
For failing to sign top overall pick Brady Aiken, the Houston Astros will get the 2nd pick in 2015 draft as well their their regular pick. The teams with the 10 worst records (top 11 picks) have their first round pick protected if they signed a qualified free agent this offseason.
This work is licensed under a Creative Commons Attribution-No Derivative Works 3.0 United States License.
Maddon's agent, Alan Nero, tells Topkin (Twitter link) that he expects Maddon will manage a team in 2015. Friedman tells Dylan Hernandez of the Los Angeles Times (via Twitter) that his new team, the Dodgers, will not be among the suitors regardless of Maddon's newfound availability.
Smoke... fire?
Buster Olney @Buster_ESPN 7m7 minutes ago
My guess on Joe Maddon: He eventually winds up with the Cubs.
It begins...
Offmanesque but
steve simmons @simmonssteve 10m10 minutes ago
An unconfirmed rumour at exec levels of baseball has Joe Maddon going to the Cubs.
Hopefully you are renting Capt Happy
mlbtr says Joe Madden has opted out of his contract with the Rays. Hmmmm....
"The Cubs feel like Russell played close to a full season after 10 extra games in Arizona, where he hit .190 in 42 at-bats and got some time at second base."
78 games (counting AFL)...yeah, that's a full season.
hope he really is healthy.
Russell done with AFL after today.
I know I do this every year, but I'm in a 12-team Fangraphs Ottoneu league and we're down some owners. Let me know if you're interested. $10 fee to Fangraphs for the year and we all paid in $40 last year for prize money, but the $40 is negotiable. Year-round activity...
if Kansas City were to beat the Cardinals this would be more fun for me, but a Giants win does make all the Dodgers fans I'm around sulk, so that's nice.
Awesome, thanks for the insight.
Long time lurker some time commenter here...I was at the AFL game AZ Phill was at and I'd have to concur that Vogelbach may be the worst fielder, period, that I've seen. Terrible hands, footwork, reactions, instincts, the whole shebang. This is a limited eyeball test so take it for what it's worth. My dad was with me and he actually referred to him as Dr. Strangeglove 2.0. His body type seems to be key inhibitor here as he's simply not built to move. He can rake, for sure, but there's no way he does anything other than DH if he makes it to the bigs.
That doesn't fit well with Theo's versatility campaign, now does it. If I was Theo, because I have a somewhat dark sense of humor, I'd play him every position in the infield.
No Raul Ibanez on WS roster, Royals become first team in WS without a player who didn't play in the 20th Century.
/per Olbermann
tell em wash
it's tough being a billionaire in obama's america.
maybe the cubs could do a Kickstarter campaign. i'm down for $5.
I think the fact that the PTBNL the Cubs owe Boston is supposedly to be named after the Rule 5 Draft might suggest that the Red Sox will be able to select a PTBNL from the list of Cubs minor leaguers who were eligible for selection in the Rule 5 Draft but were not drafted. Or it could be that the Cubs will select a player in the Rule 5 Draft for the Red Sox and then send that player to Boston as the PTBNL after the conclusion of the draft, although that is less likely because the Red Sox actually select ahead of the Cubs in the Rule 5 Draft (Red Sox se
©The Cub Reporter 2014. The Cub Reporter is in no way affiliated with the Chicago National League Ballclub.


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UTICA, N.Y. -- Senior Kelly O'Dell posted another double-double yet Saint Elizabeth saw its four-game winning streak fall at the hands of hot-shooting SUNYIT Saturday afternoon in North Eastern Athletic Conference women's basketball action.
SUNYIT (5-5, 3-1 NEAC) shot 50.7 percent on the afternoon and handed out 31 team assists in a 94-56 victory.
O'Dell paced CSE (6-6, 4-2 NEAC) with 16 points and 10 rebounds while freshman guard Amerisse Rogers added 13 points and four steals.
Saint Elizabeth travels to Lancaster Bible for its next game, heading to Central Pennsylvania for a 7 p.m. NEAC contest on Wednesday. CSE returns to St. Joseph's Hall on Sunday, Jan. 20 for a 1 p.m. game with Keuka.


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"You've Been Officially Crowned!"
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One Community/One Book: 2014 National Book Award Finalist Redeployment by Phil Klay
News From the Libraries – October 2014
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2015 Possible Journal Cancellations
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GSA picks DoD installations chief Robyn to head Public Buildings Service
Tuesday - 9/4/2012, 7:37pm EDT
Dorothy Robyn, who for the last three years has overseen the Defense Department's military facilities and buildings, has been named to head the General Services Administration's embattled Public Buildings Service.
Dorothy Robyn
In a memo to staff Tuesday, Acting GSA Administrator Dan Tangherlini, called Robyn's hiring the "next step forward" in GSA's effort to "refocus this agency on our mission to deliver value for taxpayers and consistent, effective and responsive services for customer agencies."
As DoD's deputy undersecretary for Installations and the Environment, Robyn was responsible for managing DoD's 539,000 military installations, spanning more than 29 million acres across the world.
She also headed up the department's Base Realignment and Closure (BRAC) efforts.
In particular, Robyn focused her efforts on installation-energy programs, such as building or retrofitting more energy-efficient bases. Robyn also oversaw DoD's "energy test bed" project, which would provide grants to companies that test new energy concepts on military bases."
Before being appointed to DoD, Robyn consultant with the Brattle Group, an economic consulting firm, and also served as a member of the White House staff as a special assistant to the President for economic policy.
"These experiences make her uniquely qualified to manage the extensive inventory of the Public Buildings Service as well as the task of disposing of excess and underutilized properties," Tangherlini wrote in the staff email.
Tangherlini also announced he is phasing out the PBS Board of Directors, which he suggested would streamline the chain of command at the PBS.
"By clearly establishing the executive authority of the PBS commissioner, I am enabling Dr. Robyn to set the agenda for PBS and to create a clear, identifiable chain of command," Tangherlini said. "As we move forward, I believe that this change is essential if PBS, and the entire GSA, is to give the American people the effective, efficient service that they deserve."
Robyn replaces Linda Chero, who had served as acting PBS commissioner since April, when then-Administrator Martha Johnson fired PBS Commissioner Robert Peck for his role in a conference-spending scandal at the agency. Johnson also resigned.
GSA head Johnson resigns, two other officials fired in wake of 'over the top' conference spending
GSA places deputy PBS Commissioner Foley on leave


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INGLEWOOD, Calif. (Nov. 13, 2009) — Flashover, given a perfect stalking trip by jockey Joe Talamo, rallied from third at the head of the stretch to win Friday night's $46,000 allowance feature at Hollywood Park by a half-length over Made for Magic.
The 4-year-old daughter of Unusual Heat covered one mile on the Lakeside Turf Course in 1:35.51 to win for the sixth time in 14 starts. Irish-bred Firey Red, the 6-5 favorite making his first North American start, ran far back most of the way and could only close for third in the field of five.
Flashover, trained by part-owner/breeder Barry Abrams, paid $6.40, $3 and $2.10 as the 2-1 second choice. Made for Magic returned $3.80 and $2.40, while the show payoff on Firey Red was $2.10.
The victory — worth $35,880 — increased Flashover's earnings to $241,650.
Copyright © 2009-2014, Hollywood Park. All rights reserved.


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RUMOR: Van Halen A New Album Ready To Release Next Year
Thursday, November 8, 2012
Does Van Halen have a new album prepped and ready to go for 2013? Melodicrock.com reported a rumor that when the band recorded this year's A Different Kind Of Truth album they actually recorded enough material for its followup. The rumored album could feasibly see release during the first quarter of next year as a tie-in for the next leg in Van Halen's tour.
Van Halen has been sidelined following Eddie Van Halen's intestinal surgery in September. The band came off the tour midway through their summer tour and is expected back on the road sometime in 2013.
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Value-Based Pharmaceutical Pricing
Deloitte Insights video
To transition from volume-based models to value-based pricing, companies must start with the basics. Watch this episode of Deloitte Insights to learn more.
Paul Keckley, Executive Director of the Deloitte Center for Health Solutions, Deloitte LLP
Scott Evangelista, Principal and National Commercial Leader of the Life Sciences Practice, Deloitte Consulting LLP
Sean O'Grady (Sean): Hello and welcome to Insights where today we will be discussing value-based pharmaceutical pricing, and how it differs from traditional volume-based models. For this conversation, we are welcoming back Paul Keckley, Executive Director of the Deloitte Center for Health Care Solutions, and Scott Evangelista, Principal and National Commercial Leader of the Life Sciences Practice within Deloitte Consulting LLP. Scott, we will begin with you, and I would like you to set this up for us. So what exactly is value-based pricing?
Scott Evangelista (Scott): You know, a good analogy of it would be along the lines of whether you pay somebody to cut your grass or whether you pay somebody to keep it green. You are paying for an outcome as opposed to the consumption of a volume of medicine. So, if I sold you 30 pills, you would buy 30 pills at a price per pill, but wouldn't you rather buy a cure for a disease or the control of the disease. So, value-based is when you price the utilization of something and the outcome of it as opposed to the consumption of it.
Sean: You agree with that Paul?
Paul Keckley (Paul): Yeah, but it is a word we use in health care now as much as we use quality. It means something different to everybody. The real question is "How do you measure it?" You have defined it and then how do you measure it, over what period of time? If a pill keeps me alive three months longer, but it costs five times more, what is the math, what is the calculus? So that is really what is really underneath the debate about value-based pricing: How do you do it, not whether we should do it… how you do it?
Sean: So, with that in mind, do you believe that this is a sustainable long-term strategy for pharma organizations?
Paul: I do, for two reasons. One, they have no other option because, as Scott well knows, they are in a cycle of being commoditized. So, increasingly, there is pressure on their pricing to the point where many of these companies say I just cannot afford to produce it any more. Other countries get the same compound at substantially lower price than the U.S. does. The second reason is the market demands value now. Everywhere you go, whether it is in the retailing industry, manufacturing of other — even our cars, everything is being framed as a value-based purchase now. So, this is not unique to the pharma or bio industry. This is a systemic change in the way markets in the U.S. are buying.
Sean: And Scott, I could see you were smiling during Paul's answer.
Scott: It is hard to say whether or not something is sustainable because it is not yet really defined. As Paul said earlier, there is no agreement on what value means. So, the way in which life sciences companies, medical device companies understand what value is, it might be incremental improvement over something that exists, whereas a provider says, "Well if improvement is there, that might be interesting, but can I see the improvement in clinical outcome or not?" What is an improvement to a patient versus a payor? We are really at the very early stages of figuring out what are the right methods, what are the right measures, how are we going to cooperate because you cannot do this independently. There have to be agreements between the life sciences company, the provider community, the payor community to wrap around this notion of value.
Sean: Well, that was going to be my next question -- If we are debating value here, how is this being debated in the marketplace?
Scott: In as many ways as you can imagine, right. Some people value choice. I want the right to be able to take the expensive one or the inexpensive one. It should be my choice. Payors are saying, "Wait a minute, you cannot have a choice without a financial consequence," which has been our history. Patients for the longest time have had fairly broad choices with almost no financial consequence to the choice. Again, the debate is going to rage on, and for providers, there has not been data; data is the other issue to this, right. There has not been sufficient data and information available to be able to measure by anybody's definition, the contribution of a technology to an overall outcome. Is it because you took pill A versus pill B? Or, is it because you modified your diet while you were taking pill A, and all the other things that might have happened along the course of being treated for a disease? It is very complicated.
Paul: Let us not forget that the consumer has no concept of cost. So, the equation about value involves some relationship between cost and price and a result. Cost has been disguised in this industry. It is very difficult to know what it cost a company to produce a product. It goes through the distribution cycle and ends up in your pill cabinet. So, it is not a concept. I think Scott is exactly right. It is an early discussion in an industry that has operated in a completely different framework now for its history in the U.S. Now, the U.S. has moved to value. All you have to do is to drive down highways and see the retail establishments that seem to be growing. It is a value-based economy. Now, we have this sector having to figure out how to align with that, and it is going to be bumpy. It is not going to be easy, and it starts with a complete vacuum in what consumers understand cost to be.
Sean: Let us just talk about a little bit about bumpy because earlier when I asked you about the long-term sustainability of this model, you did not flinch. You said yes, this is where the organizations have to go. Do you see bumps? Do you see drawbacks to implementing this model, and if so, what are they?
Paul: Well, the status quo is easier on the pocket books of those that benefit from the status quo. So, doctors and hospitals and health insurance plans benefit from no change. If they can, for instance, just keep ratcheting down medical device, biopharma companies on their pricing, the gaps --the margins --accrue to the benefits of others. So, how do you get doctors to think differently about the pills they prescribe? How do you get health plans to build in their models, a value-based agreement between a pharmaceutical company, a provider, the health plan, and the consumer? Should the consumer share in those savings? So, we are treading on turf that is very uncharted for the incumbents in the industry. The second one is we then have to figure out a regulatory framework to deal with it, which we don't.
Scott: The regulations in this will be very complicated. Actually, as much as we want to pay people for outcomes, there are regulations that prevent pharmaceutical companies, for instance, from discussing outcomes. As much as we want to get creative about value-based pricing, for instance, there are constructs out there where if you take a drug and it does not work, the pharmaceutical company does not get paid for that. But if that gets fed into a best-price calculation back into the federal government, then there are substantial financial penalties because it will look like a discount. So, the policy is lagging the appetite, if you will. So, that policy is going to be a big issue.
Paul: I will just add the third challenge will be the metrics and the data. We actually have to collect enough data over a period of time to refine these models. So, at the early stage, it typically takes in an industry about five to seven years before you refine a model, and think of us just at the starting line. So, it is not going to happen overnight. We are going to be doing a lot of testing of this. I simply don't think that the clock is going to turn back to everyone is selling on an average wholesale basis, and it is volume, times price, equal what the pharma company gets. I don't think that is sustainable.
Sean: I think that is going to be my last question for the two of you because it sounds like the crystal ball is a little cloudy, just based on what we have been speaking about here. So, that in mind, the next two to three years, where do you see this model developing, and how do you think it might be taken in the marketplace?
Scott: I think it is cloudy on one hand. So, make no mistake -- the competitive dynamics around health care in general, pharmaceutical and life sciences in specific, is such that this is inevitable. It will happen. How it happens will evolve. There are number of companies today that are in pretty well-defined experiments--so, life sciences companies with health care payors to do the research necessary to find the subpopulations to be able to define the metrics, to be able to assess what the outcomes are, and price them accordingly. So, people are starting to work in this model, but it will take time to refine; it will take time to evolve.
Paul: I would add that we know it will probably not be at Level 1 on the formulary in the generic world, and we know that it is going to be very difficult at Level 4, with the specialty pharma, with all of those. In specialty pharmas, one percent of the pills, if you will, is 17 percent of the spend. These are those things that work for a few people, but they are very expensive. It is going to be in Level 2 and 3. These branded drugs where there is very strong evidence about efficacy and effectiveness that we are going to figure out models to equate that to value. We will get to the specialty pharma at some point. It is just not going to happen right away.
Sean: You said before on this program, if you can measure it, you can improve it. So, it sounds like there is going to be quite a bit of measurement going forward. Gentlemen, thank you both. Okay, we have been discussing value-based pharmaceutical pricing with Paul Keckley, Executive Director of the Deloitte Center for Health Care Solutions, and Scott Evangelista, Principal and National Commercial Leader of the Life Sciences Practice for Deloitte Consulting LLP. If you would like to learn more about Paul, Scott, or any of the topics discussed on today's broadcast, you can find that information on our website. Its Deloitte.com/insightsus. For all the good folks here at Insights, I am Sean O'Grady. We will see you next time.
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