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The Phantom of the Opera Reviews
Latest Reviews
Written on January, 26th 2013
This musical is obviously excellent, it's the longest running show on broadway for a reason. Stunning sets, beautiful music, and SIERRA BOGGESS AND HUGH PANARO ARE PERFECT.
Written on March, 12th 2012
It has been a few years since I have seen The Phantom of the Opera, and particularly longer since seeting it on Broadway.
The first thing I noticed was the type of audience was not the sort of person that you often see at a Broadway show, the audience were full of tourists, who were ticking off the "see a Broadway show" on the must-do list, and bought tickets to the only show that they had heard of. This is the beauty of The Phantom, it attracts so many people who are not regular theatre goers and gives them that experience, and a desire to come back for more.
Hugh Panaro does not have the classic deep Phantom voice, his voice puts a different angle to the character of the Phantom, and slightly more like The Phantom is in Love Never Dies.
Overall, after a few years, it was like visiting an old friend and catching up, as beautiful as the first time, and the magic is still there
Written on December, 26th 2011
The Phantom of the Opera is a classic for everybody of all ages. Even for me, someone who despises classical opera, I really loved this from the moment I saw the show; it was life-changing. During the Overture, the hairs on the back of my neck stood up. I was freaked out when the chandelier crashed, and I cried in the final scene. This was the first time I saw it. The second time I saw it, the Overture was even more electrifying, I was more frightened during the Act 1 Finale, and I bawled like a baby in the last scene.
The Phantom of the Opera is a tale of seduction, romance, revenge and unrequited love. The acting was phenomenal. If you're a parent, don't fear, you can take the whole family with you. There is really no profanity, although some sensual movement. The operatic arias may bore them a little, but the title song's 80's drum-beat will surely give them a retro thrill. It also gives your a good opportunity to talk with your kids about judging by looks and accepting people for who they are.
Isn't this enough for you? The Phantom of the Opera is a spectacular classic that never gets old. Go out and get tickets already!
Written on August, 04th 2011
Have seen this production 6 times over the run of the show and I'm still left breathless and exhausted by the sheer emotional impact of the Phantom of the Opera. There is not one thing to complain about in this timeless classic. All aspects of the Broadway musical are showcased at the Majestic Theatre on a daily basis with this bittersweet beautiful love story. The entire cast is stellar and the orchestra transports you effortlessly to the Paris Opera House where you sit in box 5 (sic) and soak in the majesty of this stunning musical. Again, the Orchestra just blew everyone away with their performance,so much that a crowd of at least 100 or more people surrounded the pit as the audience exited the theatre, and saluted the orchestra with thunderous applause following the final strains of their performance. OUTSTANDING !!! I will make sure I see this at least one more time before its historical Broadway run comes to an end. And no, I'm not a 12 year old teen age girl or an investor or even a minor relative of anyone related to the show. I'm a 58 year old married man who just happens to immensely enjoy the Broadway musical in all its forms and conceptions who just happens to think Phantom is by far one of the best musicals ever.
Written on July, 02nd 2011
Absoultely amazing show, it is as good today as it was when we first saw it 22 years ago. Truley a classic of all times.
Written on July, 11th 2008
I went to see this show in April 2008 and I was completely mesmerized at this show. I was so happy that I got tickets for this show and had chills all through the show from the excitement. The singing was awesome, the sets awesomes as well (especially the Masquerade scene with the giant staircase). I was also excited when the chandelier fell and stop just above the audience's heads. I recommend this awesome show to anyone, although younger children will probably be a little bored.
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BuRiaL`: That icon is very small and saved in jpeg format, if anyone tried to make an icon out of that it would look horrible. Do you have any better quality versions available?
Looking for your own custom icon to be made for you?
I found a bigger one, No worries pIjIN
Tried my best :S, tell me if you like it:
Thanks Crunchos, I'll make your icon tomorrow, getting late here
Looking for your own custom icon to be made for you?
I just make a rounded white square like a border, use some blur effect , duplicate it if it needs to be more "hard" and then set it to "overlay" for colour match
Last edited by redeye998; 05-10-2012 at 06:03 PM.
Rate your Icon | HoN Launcher Suggestion | DeviantArt| Blog
Anonymous Love (Completed)
You liek my workz? - Donate in EUR - Donate in USD
Thanks for the image Sorry for the bad quality picture.
Last edited by BuRiaL`; 05-10-2012 at 06:09 PM.
Rate your Icon | HoN Launcher Suggestion | DeviantArt| Blog
Anonymous Love (Completed)
You liek my workz? - Donate in EUR - Donate in USD
For future reference, the "Colours" section refers to the main colour scheme of the icon. e.g. If you want an icon that is mostly green because your name is green, or you like the colour green, then put "green" in the colours section.
Looking for your own custom icon to be made for you?
Hi, firstly i want to say that you guys doing a awesome job.
Now to my dream icon
I wish i could have a similar style as s2, but with my name and without the background. (transparent)
This cat with the background (or transparent-depends on you), rounded borders and " Really?" text. (http://wallbase.cc/wallpaper/1675530)
Know i want too much, but if this could be done i would be very happy
Thank you!
PS:Hope you understand, my english sucks.
Last edited by Hutman; 05-13-2012 at 01:16 PM.
- Source image http://www.freeimagehosting.net/o47tx
- Colors wanted: Brown stripy BG
- Rounded borders: yes
- Icon gloss: yes
- Borders: no
- Text wanted: Screwed
- Others: -
Can you make those with rounded borders only? No shadow/light/anything extra needed.
Hey there,
I'd like a new CAI made of that picture
(So sorry for the size T-T)
With the text 'Like a lady.' in that typo http://www.dafont.com/fr/before-the-rain.font.
I'd like rounded corners and for the gloss... I never know..
Thanks a lot.
I Want THIS picture if you don't mind.
No background color change please, the colors are fine as is.
I would however...Thoroughly enjoy Rounded borders.
no icon gloss.
If you could add nice looking fire patterns or something of the sort that, I would like that.
Text: You Just Killed the Wrong KRILLIN.
color/background change: NO
Rounded borders: YES
Icon Gloss: NO (actually, if you could do both, one glossy, and one not, just for comparisons sake)
Border Pattern:YES (fire or something of the sort)
Text: YOU JUST KILLED THE WRONG KRILLIN. (if it wont fit, just scrap it, and thanks anyway!)
Last edited by Zalixer; 05-12-2012 at 11:18 PM.
Hey guys, i was thinking if some one could create a custom icon to me.( i suck really to make these icons)
Some thing like "KheZu´s" icon, but with my name instead ofc "swepz"
Thanks for help and please no troll
My Fayde Alt. Avatar suggestion "Hassassin Fayde":http://forums.heroesofnewerth.com/showthread.php?p=14811835

subset: commoncrawl


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Intl. (english)
On Tour
New Releases
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Create with us a set of the 100 greatest symphonies
Tell us what repertoire to put into the set, and we will find the recordings
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Pure produces Deutsche Grammophon Edition radio
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Anne-Sophie Mutter's debut recording of Dvořák's Violin Concerto
Her first album with the Berliner Philharmoniker in 30 years
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Patricia Petibon presents Poulenc's beautiful sacred works
Three humble and gripping masterpieces
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A unique combination of oboe sonorities and a cappella signing
Albrecht Mayer and the King's Singers' Christmas album: "Let it Snow"
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Bach Masterworks – the greatest ever Bach box
50 CD limited edition set
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Christian Thielemann's outstanding "The World of the Ring"
Now available on DVD and Blu-ray
Watch now!
Anne-Sophie Mutter tells the story of her new album
New video: "Drawing back the cloth in Berlin..."
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Daniil Trifonov presents his main-stage Carnegie Hall recital debut
Phenomenally blending extreme technical facility with a poetic refinement
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Bach Masterworks: The Original Jackets Collection
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Dudamel And Berlin Philharmonic Concert to be streamed live online and in international cinemas
Gustavo Dudamel's 6 December concert with the Berlin Philharmonic Orchestra is to be shown live in more than 100 cinemas in Germany, Austria, Ireland, Italy, Switzerland, the Czech Republic and the UK. He conducts - Stravinsky's Suites Nos. 1 and 2 for small orchestra, and the Fourth Symphonies of Schubert and Beethoven.
Honoured with an ECHO Klassik award in Berlin, Rolando Villazón sets his sights on Mozart
It has been a triumphant year for Rolando Villazón, appropriately crowned at Berlin's Konzerthaus on 6 October with the "Best Solo Recording/Voice (arias/recitals)" award for his highly-praised Villazón Verdi tribute at Germany's 20th ECHO Klassik ceremony. The star tenor not only collected the prestigious solo artist prize, but also performed and co-hosted the annual event, for the second time, with TV presenter Nina Eichinger.
Netrebko and Beczala triumph in Metropolitan Opera: Dazzling new Eugene Onegin opens season
The critics warmly welcomed Netrebko's return to her native Russian repertoire as Tatiana and Beczala's muscular account of Lenski. The production is to be broadcast in cinemas worldwide on 5 October, with some 60-plus countries screening the opera.
Jan Lisiecki Scoops Coveted Gramophone Award
Internationally regarded as the Oscars of the Classical Music World, the 2013 Gramophone Awards were announced on 17 September during a ceremony held at LSO St Luke's in London. Eighteen-year-old Polish pianist Jan Lisiecki has been named "Young Artist of the Year".
Hélčne Grimaud dazzles with Brahms: Album launch at Steinway's follows Hamburg concert
Following a great performance of Brahms' First Piano Concerto in the Hamburg Laeiszhalle, Hélčne Grimaud presented her new Brahms album at Steinway & Sons' legendary piano factory in Hamburg on 13 September.
Blechacz's Chopin goes Gold on day of release in Poland: Polonaises take his native Poland by storm
Polish pianist Rafał Blechacz's recording of Chopin Polonaises has gone Gold in Poland on the day of its release. The recording features seven Polonaises, including the celebrated "Polonaise Fantaisie".
Berlin's Hottest Ticket: Anne-Sophie Mutter performs Dvořák for her Yellow Lounge debut
History was made on Tuesday 3 September when a capacity audience crowded into Berlin's Asphalt club to hear Anne-Sophie Mutter give her Yellow Lounge debut. The superstar violinist held over 800 music-lovers spellbound with performances of works drawn from her forthcoming Deutsche Grammophon Dvořák album.
Deutsche Grammophon scoops "Contemporary" honours at Gramophone Awards
Deutsche Grammophon has taken the "Contemporary" honours at this year's Gramophone Classical Music Awards. Netting the Contemporary Award is Dutilleux:
an extraordinary tribute to the composer on his 97th birthday.
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Simon Bolivar String Quartet
05 Dec. 2013
Lancaster Institute for the Contemporary Arts, Lancaster, Great Britain
Simon Bolivar String Quartet
06 Dec. 2013
Mendelssohn, Brahms, Beethoven, J.S. Bach/Birtwistle, Shostakovich, Ginastera (tbd)
University of Manchester, Manchester, Great Britain
Roberto Alagna
16 Dec. 2013
Bizet: "Carmen"
Royal Opera House Covent Garden, London, Great Britain
Roberto Alagna
19 Dec. 2013
Bizet: "Carmen"
Royal Opera House Covent Garden, London, Great Britain
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Sven Helbig
Listen to Sven Helbig discussing his new album »Pocket Symphonies«.
Karl Jenkins
Watch the music video of "Naranja" from Karl Jenkins' new album "Adiemus Colores"!
Anna Netrebko
In 2013 Anna Netrebko celebrates 10 years at Deutsche Grammophon. Look back on some of her musical highlights!
Claudio Abbado
Watch this interview with record producer Sid McLauchlan, who produced many of Claudio Abbado's recordings on Deutsche Grammophon.
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text:
By Mayo Clinic staffThe PSA test is used primarily to screen for prostate cancer. A PSA test measures the amount of prostate-specific antigen (PSA) in your blood. PSA is a protein produced in the prostate, a small gland that sits below a man's bladder. PSA is mostly found in semen, which also is produced in the prostate. Small amounts of PSA ordinarily circulate in the blood.
The PSA test can detect high levels of PSA that may indicate the presence of prostate cancer. However, many other conditions, such as an enlarged or inflamed prostate, can also increase PSA levels.
There is a lot of conflicting advice about PSA testing. Ultimately, whether you have a PSA test is something you should decide after discussing it with your doctor, considering your risk factors and weighing your personal preferences.
Prostate cancer. American Cancer Society. http://www.cancer.org/cancer/prostatecancer/detailedguide/index. Accessed March 4, 2013.
- Prostate cancer screening. Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/prostate/basic_info/screening.htm. Accessed March 4, 2013.
- Ilic D, et al. Screening for prostate cancer. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004720.pub3/abstract. Accessed March 4, 2013.
- Moyer VA. Screening for prostate cancer: U.S. Preventive Services Task Force. Recommendation Statement. Annals of Internal Medicine. 2012;157:120.
- Prostate cancer screening (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/screening/prostate/HealthProfessional/page1. Accessed March 4, 2013.
- PSA. Lab Tests Online. http://labtestsonline.org/understanding/analytes/psa/tab/test. Accessed March 4, 2013.
- Prostate-specific antigen (PSA) test. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/detection/PSA. Accessed March 4, 2013.
- Hoffman RM. Screening for prostate cancer. http://www.uptodate.com/home. Accessed March 4, 2013.
- Castle EP (expert opinion). Mayo Clinic, Phoenix, AZ. April 17, 2013.
- Carter HB, et al. Early detection of prostate cancer: AUA guideline. American Urological Association. http://www.auanet.org/education/guidelines/prostate-cancer-detection.cfm. Accessed May 6, 2013.


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The president of the Humboldt Co-operative Association Limited (the Co-op) reported a year of excellent growth in 2011 at its annual meeting, May 1.
It was a year of retrospect for the local association that celebrated its 75th anniversary in 2011, and board president Rick Merkosky highlighted some of the events of the year to the 140 or so members who attended the dinner and meeting at the Humboldt Legion hall.
"Our co-op's 75th anniversary was a focal point during the year," Merkosky said. "Daily activities, events, community partnerships and a major consumer draw all centered on this milestone in the Co-op's history."
In 2011, he said the Humboldt Co-op had looked at the past with an exhibit of its history at the Humboldt and District Museum and Gallery. Merkosky said 2012 would be a year of looking toward the future, with completion of the first full year of operation of the Lanigan Food Store and plans underway for the new food store in Humboldt plus an expansion to the Lanigan Cardlock.
The annual meeting included reports given by Federated delegate Chris Weiss, store manager Phil Griffeth, and an additional report given by Federated Co-op director Beryl Bauer.
In his report, Bauer spoke about the many advantages of having a co-op in the community, and of the impressive financial status of all Federated Co-ops in the Western Canadian structure.
"When you hear about savings of $839 million and $537 million coming back," Bauer told the members, "what that means is that money stays in the local communities. It doesn't go off to some corporate head office, it comes back to you members and to your co-op to help build, expand, and grow, and that's the remarkable thing about co-ops."
Provincially, Bauer said cash-back deliveries in the last five years alone have exceeded $287 million, and the total capital invested in Saskatchewan is over $227 million.
"So co-op has certainly helped the province grow," he added.
Since the subject of growth kept cropping up in all the reports, it was only a matter of time before questions or concerns about the new food store project in Humboldt's Westwood Centre should arise during the question and answer period.
Some of the questions members asked were "what will become of the old food store when the new food store opens," "why are food prices higher at the Co-op than in other stores in town," and "will the C-store and gas bar remain open in its current location."
Griffeth explained that the Humboldt Co-op's current food store building on Main St. in Humboldt is being appraised, and the board will take a look at it, but the general plan is to sell the building.
In addressing the question of food costs, the manager strived to point out that it is impossible to compete with prices on every item in every store in town.
"We need to compete," was Griffeth's reply. "We need to compete with a new facility. We're building a new food store that costs $7.5 million, and we have to pay for the new store. We have a lot of customers that like to shop in the food store, and who want a new food store, and that all takes money."
With regard to the C-store and gas bar, Griffeth said the new food store is the first priority in the building project, and that the C-store and gas bar will remain in its current location on Hwy. 5 east in Humboldt..
"The current C-store has an excellent location," said Griffeth. "There is a higher traffic count in front of that convenience store right now than there is on the other side of the highway. About 3,900 cars per day go by that highway, so the plan is that it will continue there."
Griffeth explained that at the Westwood development, the Co-op has secured two pieces of land for its new project, located one behind the other. The one that is right on the highway (beside the Canalta Hotel) is for the future convenience store/gas bar.
"We're not going to see that for a little while," he confirmed, "but the food store, obviously, you'll see that start to happen soon."
The rest of the meeting dealt with an election of directors to the board and the annual employee Service Awards.
Three positions on the nine-member board were up for renewal this year, and the members who attended the meeting elected Mervin Ford, Scott Gehlen, and George Hinz for 2012.
The final business on the agenda for the annual meeting was the Co-op Service Awards. Every year, employees who reach certain milestones, such as five or 10 years or more, are acknowledged and receive a gift from the Co-op.


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A new bill would allow pilots to use the driver's license medical standard for noncommercial VFR flights in aircraft weighing up to 6,000 pounds with no more than six seats, as long as they carry fewer than five passengers, fly below 14,000 feet msl, and fly no faster than 250 knots.
The Civil Aviation Medical Association, which represents aviation medical examiners, is objecting to the FAA's proposed sleep apnea policy. CAMA warns that the new policy can't be justified by the scientific evidence and would place an undue burden on pilots, the medical certification process, and the nation's accredited sleep centers.
How do you approach a flight around the world—do you fly from dawn to dusk, set a leisurely schedule with lots of time for sightseeing, or shoot for something in between?
On Dec. 6, 1999, UA 1448 made one wrong turn while taxiing in severely reduced visibility at Rhode Island's Theodore Francis Green State Airport. It became the first link in a chain of mistaken assumptions by its crew and the tower controller. Learn how runway incursions happen in just seconds with this animation.
AOPA has been notified of several incidences where an alleged aircraft seller claims the sale and transaction of an aircraft will occur through an "AOPA Escrow Service." This is a phishing scam that appears to be originating out of the U.K.
Members only
The difference between a private pilot flight operation and a commercial pilot flight operation depends on whether there has been any compensation exchanged for the flight. If money passes from the passengers or the person responsible for the cargo on board, that would be considered compensation. But, could compensation mean more than money? You bet.
IFR Fix
Contemplating IFR flight scenarios for airports like Delta, Utah, is excellent review for any instrument pilot. That's because briefing for a flight into and out of Delta covers bases unlikely to be encountered on your next two-hour tour of your home field approaches.
Cessna reports "strong deliveries" of the new TTx since being awarded an FAA type certificate in June, and Brazil has followed suit.
What's your heading?" Rare is the student pilot who hasn't let distraction, or turbulence, spoil a slick stint of steady flying. Then you vow to do a better job next time of keeping track of the messages your instruments are displaying.
Through staff and Airport Support Network volunteers, AOPA advocates for members at the state and local. See the news, blogs posts, and tweets for your region.
Advocacy at the local level
AOPA is building a national Network of flying clubs and the Finder is the place to see the progress. The Finder allows you to find a club in your area or promote your established club.
Find a Club Near You
You don't need a meteorologist's understanding of weather to be a good pilot. Test your knowledge:
Check for a date and location near you »
Digital Subscribers - Click here
AOPA thanks our members for their continued support in protecting the freedom to fly.


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You're watching...
The Real Obama: Appeasement
Administration throwing in the towel when it comes to war on terror?
May 7, 2012
Pamela Geller, Mike Ghouse
You're watching...
Administration throwing in the towel when it comes to war on terror?
May 7, 2012
Pamela Geller, Mike Ghouse
Also in this playlist...
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Auto-advanceThis transcript is automatically generated
-- reaction Pam Geller and also with us is from the American to get a foundation Michael -- I go you know you and I have been at odds on a lot of things here I was right about the Muslim Brotherhood I was right about them taking power.
Even the presidential candidates.
The top candidates tier candidates in the Muslim brotherhood of have all said.
That they want to destroyed not only Israel but be a war with the United States and support al-Qaeda.
You said that wasn't gonna happen Obama said that wasn't gonna happen.
But we're negotiating with the Muslim Brotherhood were giving them taxpayer dollars.
In this case where releasing.
The enemies that we caught on the battlefield.
Thinking what.
That somehow they're gonna be nice to us the they of the Talabani is gonna be nice to America -- -- releasing.
The the our enemy combatants back to them.
Sean confrontation.
When Melanie -- Madonna's gonna fighting and Coco leading with each other never find -- We have an advantage.
We haven't had -- they can keep -- tight leash on them.
And that -- Indonesia Malaysia that -- to me it sounds pretty elusive again as they getting released by the American government that sounds that -- like -- you know.
Got -- -- get out of jail free card.
We still have to borrow one of them again I'm not let them anytime they want what we need to give them a chance to make -- -- -- was what does give the terrorists -- channels and you think the terrorists those committed to Jihad and holy war and wanted to kill Americans and kept women than bondage.
And in Afghanistan and do you believe that they got to be all of a sudden be nice good we set the break.
You can -- -- reality but you can benefit the consequences of a avoiding reality.
He is basically declared.
The war on terror over.
Two weeks ago two weeks ago and and frankly he's not just declared it over he's switched sides the very idea that we've been releasing jihadist for years.
Is not an -- he's -- it's an act of surrender.
There's actually no proof in any way shape or form that they are going to make -- was giving me -- Now we cannot we cannot end a war that we did not start doesn't -- ask Michael Michael.
Why do you know.
And taxpayers have to give a terrorist group -- you agree the Muslim Brotherhood is a terrorist group one point five billion dollars.
Why don't we get it -- -- the First Act they commit is to say Israel's their enemy the second act is to cut off energy supplies to Israel.
And the third is that and they would impose Sharia law.
And then after that -- gonna Begin a war -- Israel.
Don't why don't -- given them a penny explained to me why.
And I've given money to the brotherhood -- -- -- -- skins they would you be doing five billion dollars Michael.
-- for the purpose of keeping peace with Israel not to -- -- -- given the -- Muslim Brotherhood a terrorist organization in this case.
And -- with the -- was saying please be nice to us when it released terrorists back to you and we're not gonna tell the American people to laughter we deal.
-- chances of dealing with them.
We how much better chance of being -- -- not he's down by releasing the terrorists and giving them the money to buy bombs and and kill us then give -- the money to tell us one case I'm gonna release their leaders in another case of making kill us.
That makes sense still.
Sean we have a chance.
We have a chance on its own deal went down a chance how about the chances is that they get the death penalty like every other terrorists how -- we kill.
We're trying to kill American season.
We cannot was killed them we have done that we have eliminated is definitely -- some.
What I'm good so we just don't I'm not dimmed and I know where I live so what -- -- What if -- I can't kill them when they're free.
-- and I'm content on -- administration has no place and I want to do and then I'm gonna I don't know I don't Michael.
Michael the Obama administrator -- has no plan.
No focus no strategy in Afghanistan.
It is an absolute rout.
We have turned over the country to the Taliban what is the strategy a strategy to put the word moderate in front of what a monster ideology whether it's the bottom of the Taliban -- -- -- a chased prostitute.
The moderate Muslim Brotherhood you cannot make monsters into moderates there's no such thing they have done -- thing.
I mean when Obama went to campaigning cup pool Billick said he -- homicide bonds before he came and have to he came.
I -- so what proof do you have I think Justine say Michael we pushed all the most of you know I don't Michael but -- -- -- don't feel.
And you cannot look me in the eye and say that Khalid Sheikh -- I I do any of the tally bond or any or any of the -- bond.
Our -- -- -- anyway moderates or not good Muslims or not knowledgeable and about they are they -- -- -- but they are extremely inept -- that's -- -- -- -- -- Didn't did I ditched him as the dollar bond but there are different than al-Qaeda I think we -- helping -- Karzai is our man -- helping him.
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
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text:
Friday gold puzzle – can you crack it?
Here's a little gold puzzle for you to ponder as you're getting ready for the weekend. See if you can figure it out.
Mexico Congress approves oil bill breaking 75-year monopoly
Mexico will end 75 years of government control of its vast oil reserves after Congress approved the nation's most significant economic reform since the North American Free Trade Agreement.
U.S. stocks fluctuate on Fed bets after retail sales, jobs data
U.S. stocks fluctuated, after the Standard & Poor's 500 Index had its biggest loss in a month, as investors weighed whether improving economic data will prompt the Federal Reserve to cut stimulus next week.
Dollar rallies as retail sales gain fuels Fed taper speculation
The dollar rose for a second day after retail sales gained more than forecast last month, adding to speculation the Federal Reserve will move to trim its $85 billion of monthly asset purchases at a meeting next week.


text: We literally just came from Gaztelugatxe this morning. It was amazing! But unfortunately, we could only see it from a distance (right before the steps to the island) because they are beginning to do some construction on the path and blocked it off. The car path was closed way before the steps to the island, so we left our car... More


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Tucson 5th among the "Top U.S. Cities with the Cleanest Air"
Friday, October 26th, 2012
The makers of Honeywell's AirGenius Air Cleaner, judged 100 U.S. cities on airborne pollen levels, particulate air pollution and smoking regulations.
Breathe easy…Tucson is ranked 5th.
The full list can be accessed through the Honeywell AirGenius Facebook application.
Or scroll through the Top 10 on CNN.com.


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Split Sleeve Blouse
Starting as a small t-shirt company in designer Akiko Yasuda's apartment in Hollywood, the line quickly grew into a major contemporary label. Akiko has become well known for her great fit, beautiful colors and prints, and feminine chic. Inspired by art, vintage prints, and embroideries, her designs always flatter the female form and are on the cutting edge of fashion.
- 100% silk
- Dry clean only
- Open shoulders
- Elastic hem
- Styled with rag & bone/JEAN Boyfriend Short in Tattered.
- Styled with gorjana Delaney Square Ring in Gold.
- Styled with Marc by Marc Jacobs Bolt Tiny Bangle in Oro.
- Styled with Low Luv x Erin Wasson Temple of Poseidon Ring in Gold.
- Styled with gorjana Blake Gem Cuff in Gold.
- Styled with Luv AJ The Plain Ring Tall (Set of 4) in Brushed Gold.
- Modeled in size S. See fit guide for model's dimensions.
- Revolve Style No. AKIK-WS115
- Manufacturer Style No. X2T1581


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Goss, Porter
The latest news on Goss, Porter
A special prosecutor cleared the CIA's former top clandestine officer and others of any charges.
Dodging nuts helped prepare him for life in Washington.
The CIA director is still effectively the nation's premier intelligence job.
Porter Goss and Michael Hayden will be the guest speakers on a Caribbean cruise.


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- You are / You want
- -
- You want
- -
- Art Nouveau-Deco
Art Nouveau / Art Deco
In an age when neo-classical architecture was in full swing, Victor Horta's question was to undermine existing conceptions and bring new talents to the fore. The Brussels scene quickly became a hive of frenzied activity thanks to the contributions made by the colleagues of this visionary, who included Hankar, Strauven, Blérot, the Delune brothers, Cauchie... and more than twenty others.
- Hotels
- Bed &
Breakfast - Culture/ Go out
- Night Life
- Attractions
and museums - Monuments
- Eating
- Shopping
Horta museum
The Horta Museum is established in the private house and studio of the famous architect, Victor Horta (1861 - 1947). Built between 1898 and 1901, the two buildings are characteristic of Art Nouveau at its peak.
Victor Horta and Brussels
Victor Horta was born in Ghent in 1861. His father, a skilled cobbler, passed on to him a liking for a job well done and the perseverance that made him a perfectionist, sometimes allowing himself only three hours of sleep a night.
Henry van de Velde (1863 – 1957)
Van de Velde was trained as painter, but developed further as an architect, interior designer, designer, teacher and artistic adviser. He left an impressive oeuvre and built up an international career, boasting a great number of creations in Belgium, Germany, The Netherlands and France...
Exceptional opening to the public of three Art Nouveau mansions.
In an attempt to satisfy the extremely high demand from the public, Voir et Dire Bruxelles are pleased to announce a programme of public guided tours on of three prestigious Art Nouveau townhouses.
Guided tours : Brussels, Art Nouveau and Art Deco
Many itineraries lead to the discovery of all the Art Nouveau and Art Deco gems. Victor Horta, a pioneering architect, would confer acclaim to this artistic movement, along with other personalities such as Hankar, Cauchie, the Delune brothers, accompanied by some twenty of their colleagues.
Réseau Art Nouveau Network
The Réseau Art Nouveau Network is a European coordination network, which brings together today many European cities around their magnificent Art nouveau heritage, in order to pursue an ambitious programme of study, protection and enhancer of Art nouveau.


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Posted: Oct 13, 2012 10:25 PM by Q2 News
BILLINGS- A drunk driver injured his passenger and caused a small power outage on Saturday night in Billings.
Shortly before 7p.m., the Montana Highway Patrol and the Yellowstone County Sheriff's Office responded to South 56th Street West in Billings for a single vehicle accident.
When law enforcement arrived at the scene, they discovered a 1969 GMC pickup truck, which had swerved in to a field while heading northbound on the road.
After more investigation, the Montana Highway Patrol says the truck had collided with two power poles when the truck swerved to the right and drove through a ditch before overcorrecting and landing in a field on the opposite side of the road.
Montana Highway Patrol says there was a passenger in the truck, who was taken by ambulance from the scene with life threatening injuries.
The driver of the vehicle fled from the crash, but witnesses and county deputies were able to locate the driver, a male, in a nearby field and he was taken into custody.
Montana Highway Patrol says alcohol was the main contributing factor to that crash and that the outage affected few customers and would be repaired quickly.


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Active Travel to School
Supporting and enabling schools and their communities to increase and sustain the proportion of active, healthy and sustainable journeys to and from school.
Reducing their carbon footprint and levels of obesity through a range of resources and advice.
Review of existing school travel plans.
Support with school travel plans required as partof the planning system.
General advice on school gate congestion issues.
Support with identifying funding sources for measures, such as new cycle shelters.
Provision of national support, including an online forum, downloadable materials and a yearly conference.
Links with key partners, such as district councils, transport and Children's Services.
Opportunity to apply for Sustainable and Healthy Access Routes funding.
Provision of materials that will support your objectives, such as incentives and prizes for pupils, advice sheets for parents, publicity materials and curriculum resources.
Enabling access to road safety services.
Increase in walking and cycling levels to reduce your carbon footprint.
Improvement in road safety awareness.
Pupils arrive ready to learn through active journeys to school.
Support strategies to improve attendance.
Support with aspects of Healthy Schools agenda, specifically with obesity and road injuries.
Facilitating parental choice.
Decrease in school gate congestion.
Enabling greater independence amongst pupils.
Provide a smoother transition process with linked schools.
Rates depend on the support required. For example:
Engineering advice or providing maps would be charged at an hourly rate
General support, such as updating a travel plan or setting up walking and cycling initiatives, would be charged at a daily rate due to the level of involvement.
Contact us to find out more about our services.
The performance of the team's outputs is measured through the school census' mode of travel for all state schools.
This indicates whether there has been a decrease in car travel and if school travel plans have been successful.
School travel plans are also quality assured at a regional level to ensure standards are met.
Customer feedback is used to improve and develop this service, in line with the Quality Assurance Framework for Services for Schools.
Mechanisms for collecting the views of customers include the annual satisfaction survey and complaints, compliments and comments.
Contact us about this service
Philippa Gordon
School Travel Plan Manager
Tel: 01962 846801
Email: email@example.com
Listening to your needs
We can tailor services and develop bespoke packages to suit your needs contact us today


text:
Color Resources
Contact Us
Supply Chain Reliability
Sherwin-Williams is presently involved in JIT programs with many corporations that have specific inventory and delivery requirements.
To locate your nearest Sherwin-Williams Designated Service Center, please click here. To contact your local sales representative to discuss your inventory and delivery requirements, please click here.


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I've known Jake a long time, most of his life, in fact.
He's a fidgety dude, he's not especially cuddly and frankly some of his behaviours are downright off putting, but I love him anyway.
Jake is a Shih Tzu. He has a special place in my heart because his adoption by close friends occurred as my dad lay drawing his final breaths after a brief bout of the flu. My dad was elderly and his spirit had been sucked up by dementia a few years before he died, but it was a sad time. Jake, a little ball of fluff that fit nicely in my cupped together hands, was a happy diversion.
His adoptive parents found his transplant into their family more than a diversion. Right from the start Jake was trouble. Highly strung and demanding, he soon ruled the roost. Well, not completely, since his "big brother" Jenga was at the top of the pecking order.
Jake operates on high anxiety every waking moment. One positive outcome of this personality trait was his work as "interpreter" for Jenga. Jenga didn't bark. He assumed his people were in tune to his Shih Tzu vibes, so if they didn't happen to see him head to the back door to be let out, too bad for them. Jake took up the job of doing Jenga's barking for him, saving his older mentor from numerous scoldings.
Sadly Jake and Jenga were separated when Jenga passed away at a ripe old age last summer. Since Jenga's passing Jake's high anxiety behaviour has degenerated into pathological. He suffers anxiety attacks during which all must be dropped in order to soothe him. All attempts to discern the source of his angst have failed.
Beginning as a puppy one of Jake's least endearing qualities is his penchant for singing a full throated "aria" that sounds as if someone is subjecting him to mortal torture. This little trick is a Shih Tzu temper tantrum. The arias have gone from being a sometimes thing to a several times daily occurrence.
When Bobbi Wright of Being in Balance was interviewed for a story about her new therapies — Reconnective Healing, The Reconnection and Reconnective Healing with Animals, Jake immediately came to mind.
She claims the therapy can help with emotional, mental and spiritual issues. That certainly describes Jake. Why not give it a try?
Bobbi came to Jake's house on a sunny spring afternoon. She says her hands are able to channel the energy flow from her subject to restore a delicate interconnectedness between the meridian lines, or acupuncture lines, in her their body with the grid lines that encircle the planet.
It is this reconnection that leads to the healing she is attempting to share.
Jake certainly enjoyed being in the spotlight. Besides Bobbi and I, he had his mom and a neighbour, who has a cat with an eating disorder (as in socks, underwear, tea towels), giving him their undivided attention.
When Bobbi first arrived we attempted to give her a demonstration of Jake's aria. We all went into the neighbour's yard leaving Jake behind in his. Any other time this would be an instant trigger to the hair raising howling. Not this time. Jake just sat in his chair and looked at us. Bobbi said it was because he could already feel her manipulating his energy.
For about 30 minutes Bobbi worked with Jake. He didn't sit still for the entire time, often trotting off across the yard to investigate something going on outside the fence. Bobbi said that was no problem as she could channel the energy from a distance. Strangely for Jake he did keep coming back to her, seemingly drawn by what she was doing.
At one point Bobbi asked Jake if he wanted her to touch him and he immediately starting doing some odd gyrations helping her to touch just the right spots. Early in the procedure he was perched on my lap and engaged in some serious licking behaviours. He often licks while enduring pain, but that didn't seem to be the case this time. It was as if he was experiencing something and was anxious about it.
Later he yawned frequently, which is Shih Tzu for, "what the hell?"
After Bobbi pronounced the procedure complete she said Jake might be inclined to just lie around for awhile and we were amazed to see him do just that, on the ground! Jake is not a ground kind of dog. If there is a chair or a lap he's on it. In this case he had choices of both and he was reposed with his little butt under him. That was unusual too, because the only other time he is a ground lying kind of pooch is when he is overheated. Then he's flat with all four feet splayed.
She also said Jake would be in a stage of high energy the following day. His mom rolled her eyes. Jake is always in a state of high energy, but Bobbi assured her it would be a "good" kind of energy.
Shortly after Bobbi departed Jake's absolute favourite guy in the world, the Treat Man, arrived. Jake bounded up from his uncharacteristic repose beneath the patio table and launched into his circus dog imitation, leaping chest high to make sure the Treat Man knew he was there. Unfortunately the Treat Man decided to return to his car for his jacket and sunglasses before sharing the treats Jake knew he had. Instant aria!
Jake arose a little earlier than normal the next day, but other than that his mom said his behaviour was normal, well at least what passes for normal in Jake. Bobbi did caution her treatment might take more than one session to be effective. We decided after the Treat Man destroyed in 20 seconds what she had accomplished in 30 minutes we would probably be wasting her time.
It was interesting, however, to watch her work and listen to her talk about working with large animals such a horses. She has an engaging manner, illustrating her empathy and serious application of an ability she has difficulty explaining, but in which she believes implicitly.


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Test ID: MNU
Manganese, 24 Hour, Urine
Secondary ID A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Monitoring manganese exposure
Nutritional monitoring
Clinical trials
Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Mn (Manganese)
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube (Supply T068) or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. No preservative.
3. See Metals Analysis-Collection and Transport in Special Instructions for complete instructions.
4. Refrigerate specimen within 4 hours of completion of 24-hour collection.
Additional Information:
1. 24-Hour volume is required.
2. See Urine Preservatives in Special Instructions for multiple collections.
3. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Urine Preservative Collection Options
Ambient | Yes |
Refrigerated | Preferred |
Frozen | Yes |
6N HCl | No |
50% Acetic Acid | No |
Na2CO3 | No |
Toluene | No |
6N HNO3 | No |
Boric Acid | No |
Thymol | No |
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
Hemolysis | NA |
Lipemia | NA |
Icterus | NA |
Other | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
Specimen Type | Temperature | Time |
Urine | Refrigerated (preferred) | 28 days |
Frozen | 28 days | |
Ambient | 7 days |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Manganese (Mn) is an essential trace element with many industrial uses. Manganese is the 12th most abundant element in the earth's crust and is used predominantly in the production of steel. These industrial processes cause elevated environmental exposures to airborne manganese dust and fumes, which in turn have lead to well-documented cases of neurotoxicity among exposed workers. Mining and iron and steel production have been implicated as sources of exposure.
Inhalation is the primary source of entry for manganese toxicity. Signs of toxicity may appear quickly or not at all; neurological symptoms are rarely reversible. Manganese toxicity is generally recognized to progress through 3 stages. Levy describes these stages. "The first stage is a prodrome of malaise, somnolence, apathy, emotional lability, sexual dysfunction, weakness, lethargy, anorexia, and headaches. If there is continued exposure, progression to a second stage may occur, with psychological disturbances, including impaired memory and judgment, anxiety, and sometimes psychotic manifestations such as hallucinations. The third stage consists of progressive bradykinesia, dysarthrian axial and extremity dystonia, paresis, gait disturbances, cogwheel rigidity, intention tremor, impaired coordination, and a mask-like face. Many of those affected may be permanently and completely disabled."(1)
Few cases of manganese deficiency or toxicity due to ingestion have been documented. Only 1% to 3% manganese is absorbed via ingestion, while most of the remaining manganese is excreted in the feces. As listed in the United States National Agriculture Library, manganese adequate intake is 1.6 mg/day to 2.3 mg/day for adults. This level of intake is easily achieved, without supplementation, by a diverse diet including fruits and vegetables, which have higher amounts of manganese than other food types. Patients on a long-term parenteral nutrition should receive manganese supplementation and should be monitored to ensure that circulatory levels of manganese are appropriate.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
0-15 years: not established
> or =16 years: 0.1-1.2 mcg/specimen
Interpretation Provides information to assist in interpretation of the test results
Manganese in urine represents the excretion of excess manganese from the body. Elevated levels may indicate occupational exposure or excessive nutritional intake.
Specimens from normal individuals have very low levels of manganese.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Normal specimens have extremely low levels of manganese; therefore, elevated results could easily be a result of external contamination. Precautions must be taken to ensure the specimen is not contaminated. Metal-free urine collection procedures must be followed.
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Levy BS, Nassetta WJ: Neurologic effects of manganese in humans: A review. Int J Occup Environ Health Apr/Jun 2003;9(2):153-163
2. Paschal DC, Ting BG, Morrow JC, et. at. Trace metals in urine of United States residents: Reference range concentrations. Environmental Research 1998;7:53-59
Method Description Describes how the test is performed and provides a method-specific reference
This assay is performed on an inductively coupled plasma-mass spectrometer in dynamic reaction cell mode. Calibrating standards and blanks are diluted with an aqueous acidic diluent containing internal standard(s). Quality control specimens and patient samples are diluted in an identical manner. In turn, all diluted blanks, calibrating standards, quality control specimens, and patient specimens are aspirated into a pneumatic nebulizer and the resulting aerosol directed to the hot plasma discharge by a flow of argon. In the annular plasma the aerosol is vaporized, atomized, then ionized. The ionized gases plus neutral species formed in the annular plasma space are aspirated from the plasma through an orifice into a quadrupole mass spectrometer. The mass range from 1 amu to 263 amu is rapidly scanned multiple times and ion counts tabulated for each mass of interest. Instrument response is defined by the linear relationship of analyte concentration vs. ion count ratio (analyte ion count/internal standard ion count). Analyte concentrations are derived by reading the ion count ratio for each mass of interest and determining the concentration from the response line. (Unpublished Mayo method)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Tuesday, Thursday; 3 p.m.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
Result ID | Reporting Name | LOINC Code |
8080 | Manganese, 24 Hr, U | 8203-2 |
TM26 | Collection Duration | 13362-9 |
VL24 | Urine Volume | 3167-4 |
867 | Mn Concentration | 21382-7 |


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ok this is my second big red project and i am building a set up with the funds they are giving me for the equipment right now i have ordered
MacPro 8core with
10gb of ram (memory)
(1) 320gb hd
(3) 1tb hd for internal storage (all 32mb cache)
and the stock video card the ATI Radeon HD 2600 XT 256M
i have all the other things i would need
(2) 24inch montiors
mackie speakers
mackie mixer
the software i am using is
and redcine
The question i'm coming to is the video card , my old mac has the same one and i have heard rumors that redcine uses alot of your memory card (maybe thats why it can't play full speed at higher qualities in redcine)
so i know they are ddr3 video cards in macs, would it make a big difference going up to a 512mb card or 1gb video card?
will it help the render and playback in redcine?
what would you suggest?


text:
A Triumph in the War Against Cancer
Oncologist Brian Druker developed a new treatment for a deadly cancer, leading to a breakthrough that has transformed medicine
- By Terence Monmaney
- Photographs by Robbie McClaran
- Smithsonian magazine, May 2011, Subscribe
There's a photograph of LaDonna Lopossa that helps tell the story. She's all smiles, lying on the grass in a vaguely Betty Grable manner atop her own cemetery plot. The portrait was her husband's idea—in their decades together it seems George, a.k.a. Mr. No Serious, never saw a gag he didn't like—but it was LaDonna who came up with the cheesecake pose.
"OK," George had said, "now take off your shirt."
On the one hand it's a silly snapshot of a 60-year-old woman in a cardigan and sensible sandals in Winlock, Washington, one sunny day in May 2000. On the other hand it's a glimpse of a possible future in which science has solved a fearsome problem. For this is how LaDonna and George faced her lethal cancer, not just whistling past the graveyard but clowning around in the middle of it.
Three months before, LaDonna was lying in a hospital bed in Olympia about to draw the curtain. There was a lot to let go of: four grown children, several grandkids, friends at church, a good marriage. (Never mind that as she lay there George was loudly telling the nurses he was going to hit the bars to find another wife, which she understood as his oddball effort to ease her mind.) She was ready to leave everyone and all those things and more because of the pain.
Her spleen, normally tucked beneath the lowest left rib and no bigger than a peach, was so engorged with white blood cells it was the size of a cantaloupe. She could hardly walk. Her skin was ghostly, her blood dangerously short of red cells. To breathe was a chore. Regular vomiting. Stabbing aches deep in her bones, where the marrow was frantically cranking out white cells, or leukocytes. Recurring fevers. And cold, strangely, unnervingly cold: she was freezing under the hospital blankets.
She was too old and too sick to undergo a bone marrow transplant, a grueling, highly risky treatment for her blood cancer, chronic myeloid leukemia (CML). She had already tried the other standard CML treatment, regular doses of the powerful compound interferon. But it so intensified her nausea, fevers and bone pain she abandoned the medication, come what may. With nothing left in their leukemia-fighting arsenal, the doctors were down to Dilaudid, a derivative of morphine, the narcotic painkiller. It was calming, it was comforting and for a patient in her condition it was, of course, the end.
George had given away most of her belongings and had reserved a U-Haul truck to cart his stuff to Southern California, where he would move in with one of their sons. The music for her funeral was chosen, including "Because I Have Been Given Much," to be sung by the grandkids. When the hospital recommended moving LaDonna to a hospice, George took her home instead and followed her doctor's advice to summon the children; Terry, Darren and Stephen flew up from the Los Angeles area, and Kelly drove over from her place in Winlock. One by one they went into the bedroom, sat at LaDonna's bedside and said goodbye.
CML is one of the four main types of adult leukemia, but it is not common, striking 5,000 people in the United States each year. As a rule, it is fatal, with most patients dying within five years of being diagnosed. The first phase, a stealthy explosion of otherwise normal white blood cells, can last months or years; patients are often alerted to the condition by a routine blood test. If the disease goes unchecked, the white cells become increasingly abnormal, issuing helter-skelter from particular stem cells in bone marrow called myeloid cells; such leukocytes burst capillaries, overwhelm organs and suffocate tissues by crowding out oxygen-carrying red blood cells. The disease's course is exceptionally predictable, physicians say, but its clockwork nature has also provided scientists with an opportunity: prying into the molecular gears and springs that propel CML, they understand it better than any other cancer.
Once, in early December 1999, George was driving to see LaDonna at the hospital in Olympia and stopped at a Safeway to buy a newspaper. Mr. No Serious is an avid reader, had even briefly run a bookstore with LaDonna, and he devoured the paper in her hospital room. As it happened, an experimental leukemia treatment was then making headlines. "Leukemia Pill Holds Promise," the Associated Press reported, saying CML patients "had normal blood counts within a month of beginning treatment." The study was then underway at the Oregon Health & Science University (OHSU) in Portland.
George hurried out of the hospital room to find LaDonna's oncologist.
Target for Intervention
A steep, winding, tree-lined road leads to the main campus, which is perched near the summit of 574-foot-high Marquam Hill and on foggy days appears to float above the city like a castle in a fairy tale. Another route up to OHSU is the Portland aerial tram: two Swiss-made gondola cars of gleaming steel soar on cables high over Interstate 5, whizzing people back and forth between the west bank of the Willamette River and a hospital platform perched closer to the edge of a cliff than disembarking heart patients might wish it to be.
Brian Druker arrived at OHSU in 1993, years before the tram would be built and the hall-of-fame mural in the adjacent passageway would include a picture of him. Tall, as lanky and lightfooted as a greyhound, soft-spoken, Druker was 38 and had just spent nine years at the Dana-Farber Cancer Institute, part of Harvard Medical School, in Boston. "I saw cancer as being a tractable problem," he recalled of the research path he chose after finishing medical school at the University of California, San Diego. "People were beginning to get some hints and some clues and it just seemed to me that in my lifetime it was likely to yield to science and discovery."
Subscribe now for more of Smithsonian's coverage on history, science and nature.
Related topics: Disease and Illnesses Treatment Theories and Discovery Scientific Innovation
Comments (54) |
Ponatinib is one of the medications currently under investigation for its ability to treat CML and ALL (via http://www.rxwiki.com/ponatinib). Is there any news on when this will hit the market?
Posted by dailyrx on December 13,2012 | 03:36 PM
Dr. Druker well deserves Nobel Prize! His work ushered the era of effective treatment of metastatic stage IV melanoma, for example. For 40 years no one knew how to effectively combat this disease. It killed a lot of young people, including Bob Marley. PLX4032 (aka vemurafenib, trade name Zelboraf) is now FDA-approved. GSK prepares even better stuff- dabrafenib+tamatenib (BRAF+MEK inhibitor combo). Now the research in targeted therapy is exploding, and Dr. Druker ushered this watershed!
Posted by Gregory Pribush on October 24,2012 | 07:40 AM
this was very well writen. it's very thourgh amd keep writing stuff like this i enjoy reading it.
Posted by bryan wines on May 22,2012 | 02:16 PM
Posted by jneppz on May 2,2012 | 01:06 PM
Dude you a boss thanks man you awsomes
Posted by Munoz on May 2,2012 | 01:05 PM
My mother was diagnosed with lukemia 11 years ago. she had from what i can understand two types, of the blood and of the bone marrow. they doctors here in spain managed to cure her of the blood but she has been on gleevec to treet the bone marrow for the past 11 years. in the past year she has been suffering from problems, fatuige, water retention, and she has been told after blood tests that she is very aneemic. they started giving her injections and pills to balkance her iron deficiency out but in the end they have found out that it is the gleevec that is causing the problem. in the last week they have taken her off gleevec and she has started taking another medication. as a result it has knocked her for 6 and she can barley walk around . they had to give her an emergency blood transfusion two days ago and it has made her worse. she is suffering from vomiting and nausea, and is constantly sleeping or out of breath. she has no apitite at all and no energy. I was suprised that they did not keep her in at the hospital to monitor her after the transfusion but i suppose due to all the doctors and nursing cuts here in spain, she would just be filling up another bed. i am truly conserned about her. do you have any suggestions as to how she sould prosceed and is what she is going through normal after a medication change and transfusion ? i would very much apreciate your advice.
many many many thanks,
Frank from spain, mallorca
Posted by frank on January 21,2012 | 01:40 PM
It is truely amazing how Gleevec came to be. Thank You Dr. Drunker and all the other doctors who put forth the effort to bring this to us. My husband was dx Sept 17 2003 intially statred gleevec for two years then he became resisant. He actually particapted in first phase trials for sprycel which actually just concluded a couple months ago. What a blessing for us to have this drug and several more if needed.
Posted by Tammy on October 13,2011 | 01:30 PM
I was so excited to read this article a friend told me about it. It was nice to see the person who came up with this drug. Praise the Lord Dr. Druker found this and he wanted to help others. So glad he he didn't give up. I was just diagnosed with CML August 15, 2011. Praise the Lord I don't have to go through the agony so many others have endured. What a mighty God we serve!! :)
Posted by Angie Burns on September 24,2011 | 10:42 AM
I have Hemochromatosis for over 20 yrs & was recently found to be in early stage of CLL which was confirmed by 2 blood tests. I also am slightly Anemic. I am 81 yrs young and in general good health. If there are any test programs I would be interested.I am presently being monitored at Sloan Kettering
ThANK YOU.
Posted by susan miller on August 6,2011 | 03:12 PM
I was diagnosed with a very rare form of CML after a routine blood test in August 2005. The difference versus regular CML is that my mutated gene is 5;12 and not 9;22. I was blessed to have been offered Gleevec through M D Anderson, Dr. Susan O'Brien and Lizzy Pavel PA and I'm in a testing protocol for my rare form of CML like disease. To make a long story short, I've been in complete remission for 6 years since taking Gleevec in November 2005. I thank God first, and al the researchers and MD's that made this targeted cancer drug successful and available. I hopeful that by being in a testing protocol that the drug will be available to anyone who needs it. Gleevec is still not FDA approved for my disease, therefore not available through Medicare D. The only way I got the Gleevec in 2006 was through a company retirement secondary benefit drug program. I got the Gleevec to in November 2005 and then our wonderful government took it away me in early 2006 when Medicare D stared. I have only contempt for our wonderful Medicare D program. After all, the only reason to have medical insurance like all insurance, is to cover the very serious situation. After paying into system at max. Level for 40 plus years, the medicare drug wasn't,t there when I needed it!!!
Gleevec worked for me and I continue to monitor blood and bone marrow once a year at M D Anderson in Houston.
When I hear about previous treatments for this blood disorder, I, so blessed to have Gleevec. Thanks be to God, I'm truly grateful!
Posted by Charles Hannah on July 14,2011 | 05:00 PM
After reading this wonderful article, Dr Brian Druker is my hero! Last month my dear brother, William E. Barnett of Williamsburg, VA was diagnosed with CML! Thank goodness for Dr Druker's research to discover the "miracle drug" Gleevac! In 1 1/2 months he is back to work and doing great! There are no words but to say "Thank You, Thank you!" over and over again.....
Bud's sister in California
Posted by Cindy R. Jagger on July 5,2011 | 09:01 PM
Would this drug help ALL patients?
Posted by Tina McAninch on July 5,2011 | 10:09 AM
Cancer is one of the most typical diseases in the Western countries. Its seriousness is seen in many countries where as many as every third person dies of it, and it is the second most common cause of death immediately after the cardiovascular diseases. Especially cancer of the lungs has become very common, and for example in the United States, it takes more victims than any other type of cancer.
Posted by telson on June 27,2011 | 12:47 AM
My Dad is 72 and is currently going thru chemo for AML..can this drug help him?
Posted by Scott on June 22,2011 | 01:35 PM


text:
'I Pray My Daughters Have a Life like Mine.'
House, Karen Elliot, Newsweek
Byline: Karen Elliot House
These were the words of the devout, conservative matriarch with whom Karen Elliott House lived as she wrote her definitive new book on modern Saudi Arabia. Here, she describes the surprising lives of women in the kingdom.
An hour outside the Saudi capital of Riyadh, in the rocky terrain of the desert, a Saudi family concludes a daylong outing. A full moon illuminates the black line of silhouettes in prayer. While I sit by myself on a blanket nearby, Ahmad and his father, brother, and young sister prostrate themselves in the direction of Mecca. Observing my failure to pray, Ahmad, who is 6, approaches, clearly concerned. "I need to teach you something," he says. "What?" I ask. "Do you know what to say when the angel of death comes?" he says. Assuming I do not, the little boy then provides the answers that the dying should give if they want to transit successfully to the hereafter: "The angel asks you, 'Who is your God?' and you say, 'Allah,'?" says Ahmad. "?'Who is your prophet?' You say, 'Muhammad.' 'What is your faith?' You say, 'Islam.'"
It is hard to imagine a child of that age in the U.S., or most other societies, similarly concerned about the hereafter for himself--let alone for a stranger. But this 6-year-old believer, seeking to save the soul of an infidel, suggests how pervasive religion is in Saudi Arabia. Several times every day, businesses throughout the kingdom close for half an hour at a time while men go to pray. (As the sexes are strictly segregated, women are not allowed in the mosques with the men and so have to pray at home.) Every airport, shopping mall, and government building includes an area covered with prayer rugs arranged to indicate the direction of Mecca, so worshipers know where to kneel and pray. Every hotel room has a sticker on the wall or desk with an arrow pointing toward Mecca. Even new cars often include complimentary prayer rugs so travelers can stop alongside a road and pray. The sound of the muezzin calling the faithful to prayer begins in predawn hours and is heard four more times throughout the day and evening from mosques so numerous that the effect in the larger cities is a chorus of prayer calls in surround sound.
On a recent morning, Lulu (short for Loulwa) pushes open the heavy steel door in the wall that surrounds her home. A woman in her early 40s, she is hidden under her billowing black abaya. Although the dusty street outside her house is empty, she is careful to avoid exposing even a glimpse of herself as she ushers me into the small courtyard of the modest two-story home she shares with her seven children and her husband--every other day. On alternate days, he is downstairs with his first wife of nearly 40 years, with whom he shares eight other children, all older than Lulu's brood, who range in age from 5 to 20. "That is her home, and up here is mine," she says with a nod toward the ground-floor door of the first wife as we climb the tiled stairs to her home.
A sweet woman, educated at King Saud University, Lulu speaks English haltingly. But, deeply devout, she is eager to share her religion. Though Lulu and her husband are educated and middle class, Lulu staunchly opposes women who have been fighting for the right to drive and for other freedoms, seeing them as dangerous infidel influences from the West. While Saudis these days have access to the Internet, hypermodern shopping malls, and hundreds of satellite channels--even illicit drugs and alcohol--her home is free of infidel influences. The walls of her home, like those of any devout Wahhabi, are devoid of photos because any human representation is forbidden by this strict interpretation of Islam. The family has one television, but it is set to receive only a religious channel that bans any appearances by women. Lulu doesn't want her children seeing faces of unveiled women who have recently been allowed to work as anchors on some Saudi channels. The family's sole computer, similarly, is used only under Lulu's supervision--and then only for homework, most of it studies of the Quran or for accessing religious sites.
By choice, Lulu rarely leaves home. During the week I spend with her (and on subsequent visits), it is clear that Lulu not only accepts but welcomes the confines of her life. She is the primary caregiver to her seven children and has no household help, as the salary of her professor husband can't cover maids for both wives and Islam requires that a husband treat his wives equally. And Lulu has no aspirations beyond living a life that pleases Allah and ensures the entry of her and her family into paradise. An essential element of achieving this goal is serving every need of her husband, a professor of Hadith, the thousands of stories about the words and deeds of Prophet Muhammad, collected and passed down after his death as a daily-living guide for devout Muslims. If her husband should be dissatisfied with her--or worse yet, be led astray--the fault would be hers. "Men are in charge of women," says the Quran. "So righteous women are devoutly obedient, guarding in (the husband's) absence what Allah would have them guard." Serving Allah means serving her husband.
Lulu's children, including her teenage girls, admire and obey her. And her 19-year-old daughter submits to her control of music to be downloaded on her new MP3 device. Proper Islamic music, Lulu says, must have no rhythm nor include a woman's voice lest a man hear it and be led astray--a sin upon the female. When I ask Lulu how she hopes her daughters' lives will differ from hers, she doesn't hesitate. "I pray they have a life like mine," she says. Her eldest daughter, a student at King Saud University, says with admiration, "She is dedicating herself to helping us have a life just like hers."
During more than three decades of covering Saudi Arabia, I have been fascinated with the role of fundamentalist Islam and the hold religion has on society. Researching a forthcoming book, I recently spent a week living with Lulu's devout family in Riyadh (a different and much more conservative one than Little Ahmad's family) in order to understand the role of religion in everyday life.
Like Lulu and her family, most Saudis practice an ultraconservative form of Islam known as Wahhabism--the fundamentalist form of Islam that motivated the Islamic jihadists responsible for the 9/11 attacks and more recent violence. Yet, paradoxically, Saudi society itself has seen very little turmoil or trouble. Ruled by King Abdullah bin Abdulaziz, this is an absolute monarchy. There are no elections or other political freedoms. The winds of change ushered in by the Arab Spring in Tunisia, Egypt, Libya, Yemen, and now strife-torn Syria--and fanned to violence during the recent anti-American protests sweeping across the Mideast--have not visibly touched the Saudi kingdom.
Increasingly, however, there are signs that the Saudis might not be able to hold onto the status quo, with women and youth at the forefront of a demand for change. For instance, one young Saudi woman this spring did the unthinkable--she stood up to the religious police who stalk the streets to enforce Wahhabi religious strictures on women. When the men ordered her out of a Riyadh shopping mall for wearing red nail polish, she held her ground, told them they had no right to harass her, turned the camera of her cell phone on the men to film the entire confrontation and posted it on YouTube, where it quickly went viral.
Lulu and her daughters represent the cloistered and benign Islamic conservatism that the Al Saud and its religious partners, the Council of Senior Ulema, profess to believe dominates the kingdom. Lulu wishes she were in such a majority but says fewer than 50 percent of women any longer share her views and lifestyle.
Saudi women such as Manal al Sharif, a divorced mother who worked at the kingdom's oil company, Saudi Aramco, in Dhahran, braved arrest for daring to drive--something Saudi women are forbidden from doing. Additionally, after a six-year effort, women finally are being allowed to work as saleswomen in lingerie stores. Conservative Saudis had fought the idea of female sales personnel, arguing it would lead to the mixing of men and women, forbidden by Wahhabism. (Never mind that such mixing occurred when women purchased lingerie from male sales staff.) And no less a figure than King Abdullah's daughter, Princess Adelah, has helped Saudi women establish homes where battered women can flee abusive male family members. She also helped secure a fatwa, or religious ruling, from the kingdom's grand mufti that family violence isn't a husband's right but rather a crime. Of course, it takes more than a religious ruling to alter centuries of tradition.
There seems little doubt that if the greater openness of recent years that has allowed some Saudis to choose a more liberal lifestyle--where men and women sometimes mix, where women can check into a hotel without a male relative, where there is even talk of women being allowed to drive--were to become the new norm, conservatives like Lulu would resist adapting with all their might. This is the challenge for the kingdom: how to accommodate those citizens who want more freedom to change and also those like Lulu and her family, who truly see change as a road to hell.
For sure, that task is growing ever more difficult as the historic supports of Al Saud control are weakening. Islam, long a source of unity, is now becoming another source of division and for several reasons. The Al Saud, whose legitimacy rests on perpetuating the one true faith, have politicized Islam, using the religious establishment to condone Al Saud political priorities from basing U.S. troops in Saudi Arabia in the '90s to supporting a new university that mixes men and women in 2009. As a result, the religious establishment's credibility is eroding and along with it the legitimacy of the Al Saud. Moreover, thanks to the Internet, the Wahhabi religious establishment no longer has a lock on interpreting Islam for young Saudis, who hear many discordant views from Muslims inside and outside the kingdom.
As the religious pillar weakens, so too does the future of oil dollars that the Al Saud have relied upon to purchase public passivity. Saudi oil production is believed by some experts to be nearing a peak. Undeniably, domestic energy consumption is skyrocketing, reducing available oil for export, the major source of revenue in Saudi Arabia's one-dimensional economy. The kingdom is far from broke, but Jadwa Investment, a large financial institution in Riyadh, projects that by 2014 lavish spending to buy public quiescence will exceed oil revenue, forcing the kingdom to spend its foreign currency reserves or face potentially destabilizing spending cuts.
Finally, the royal family itself is nearing a potential point of crisis. For six decades the monarchy has passed from one son of the founder, Abdulaziz, to the next. But this line of brothers is running out. King Abdullah is nearly 90 and ailing; his crown prince is 76; and the youngest of his remaining 43 brothers is nearly 69. At some point soon the extended royal family of some 7,000 princes is going to have to pass the crown to one of the grandsons of the founder. At stake for the family is not simply who gets to rule but the prospect that the selected prince's branch of the family will then pass the crown to its sons in perpetuity, precluding other branches from ruling again. If the family divides, so likely will the country.
Assaulted by technology and globalization, tipsy from a population explosion that has left 60 percent of Saudis age 20 or younger, and facing a potential succession crisis, the Al Saud continue to rely on religion as their anchor in a sea of change.
Lying on my pallet on the floor of Lulu's home, I awake at 4 a.m. when the muezzin in the nearby mosque begins to call "Allahu akbar," or "God is most great." "Hurry to prayer. Hurry to salvation. Prayer is better than sleep." Lulu's husband and two teenage sons rush to the mosque.
When her husband is home, I am banished to my room. During the week I spend with Lulu, I see her husband only once--when he picks us up from a rare outing to her sister's home. Fully veiled, I slip into the seat behind him but we are not introduced and the conversation continues as if I were as invisible as Casper the ghost. A devout man would never commune with an unrelated female--even veiled.
Lulu and her household illustrate the deep and genuine commitment of millions of Saudis to their religion, long a pillar of stability in a kingdom with deep historic divisions between regions, tribes, and sects.
Doing Allah's will is Lulu's consuming focus. At age 19, when her husband offered himself to her family, Lulu willingly chose to be a second wife. "I prayed to Allah, 'let me do this if it is good.'?" Even when her husband and children are out, Lulu almost never leaves home. Asked if she would like to drive, she seems truly puzzled. "Why would I want to drive? In Islam it is a man's responsibility to drive his wife and children."
At home, this genuinely devout woman focuses on trying to save me. Converting an infidel to Islam entitles one to paradise, she believes. And just as my conservative Christian father forbade shorts and pants, Lulu tells me that my pants and sweater are not pleasing to God because anything that reveals the human form is forbidden. My floor-length black abaya similarly is gently criticized for its fit and decoration of a blue and orange braid on its long sleeves. Fingering the offending braid, she says, "This is wrong. Your abaya shows the body, and this decoration attracts men to look at you." Outside the home Lulu and her daughters shroud head to toe in shapeless black abayas that are akin to wrapping oneself in a black bedsheet. They also cover their faces with a separate black niqab that features a slit for the eyes, but these devout ladies cover even that slit with another black cloth, which can be flipped up or lowered depending on the need to see clearly.
To assist her conversion effort, Lulu sits me before her computer to view an hourlong video on YouTube of a fundamentalist Christian preacher from Texas explaining his conversion to Islam. When this doesn't produce a convert, she issues a stern warning: "It is very bad to die believing Allah had a son," debunking Jesus as the son of God. When I observe that Christians, like Muslims, believe in one God, she rejects any equation between the two religions. "No," she says emphatically. "You must believe in Islam. Allah says this."
When the conversion effort fails, Lulu assumes it can only be fear, not any failing of Islam. "Why are you not a Muslim, Miss Karen? What stops you? Are you afraid of some people in your country when you go home?"
To the supple Al Saud, religion is an asset to be cleverly employed to preserve power. To the inflexibly Islamic--Lulu and some millions like her--religion is an inviolable pathway to paradise.
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Publication information:
Article title: 'I Pray My Daughters Have a Life like Mine.'.
Contributors: House, Karen Elliot - Author.
Magazine title: Newsweek.
Volume: 160.
Issue: 14
Publication date: October 8, 2012.
Page number: 56.
© 2009 Newsweek, Inc. All rights reserved. Any reuse, distribution or alteration without express written permission of Newsweek is prohibited. For permission: www.newsweek.com.
COPYRIGHT 2012 Gale Group.
This material is protected by copyright and, with the exception of fair use, may not be further copied, distributed or transmitted in any form or by any means.


text:
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text:
Zane begins his Viking adventure where he chills out in an ice bar and goes pint for pint of Carlsberg Beer with young Danish guys. He heads north to Aalborg where he's greeted with a "bang" from the local Cannon Lodge.
Aired: 05/22/2008
Zane battles a cave full of real monkeys in search of his mascot, stuffed monkey "Pleepleus." He takes on a cocktail called "J.C.'s" and samples a slew of beers in this tiny British outpost between Spain and Africa affectionately known as "The Rock."
Aired: 05/15/2008
Zane "lays in a course" for Las Vegas where he warns that drinking and gambling don't mix and ends up with a shiner.
Aired: 05/9/2008
Zane gets a medicinal boost from a local herbal doctor, visits one of the world's largest mini-bottle collections and learns about a rare martial art called Drunken Monkey Kung Fu.
Aired: 05/1/2008
Zane drinks with a 'Count' and gains membership into two bizarre fraternal orders where he uncovers the truth about Port Wine. Along the way, he imbibes a mysterious drink said to create an 'eternal sunshine' in the mind.
Aired: 04/24/2008
Zane's playing bartender on a Copacabana beach. He buys a skimpy "mankini" swimsuit and learns why Cachaca is the national drink.
Aired: 04/17/2008
Zane visits Valparaiso and tackles Chilean wines at an oceanfront restaurant at sunset. Then it's off to recreate "Top Gun" by making powerful "Pisco Sours." Zane and friends push a bar owner to the limits while playing drinking games. The lights are dimmed--will they get kicked out?
Aired: 04/10/2008


text:
I've been thinkin' lately 'bout building my own e-mando based on Nash the Slash's custom mando.
What would be the best pickup to use? Would it be better to plan a four or eight string mando?
Look forward hearing from you.
I've been thinkin' lately 'bout building my own e-mando based on Nash the Slash's custom mando.
What would be the best pickup to use? Would it be better to plan a four or eight string mando?
Look forward hearing from you.
pickup selection depends on your sound preference .
a stratocaster format pickup is fairly compact, those are wound in many ways.
blades are less fussy on location of pole directly under the string , but a magnetic field is not focused like a flashlight.
4 string would be less subject to the 2nd one of the course being a wee bit out of unison, bendable; or that bit of phase dissonance may be useful.
if you build it in such a way as to make the pickup easily changed , you can try several, and see which is You.
build 2?
I like my 4 string in 'dola pitch CGDA, stacked humbucker type pickup.
writing about music
is like dancing,
about architecture
Nash's emandos, built by Vladimir Bosnar, are based on the Gibson EM200:
Therefore you'll want 8 strings and a pickup equivalent to the 4-pole P-90.
Emando.com: More than you wanted to know about electric mandolins.
Notorious: My Celtic CD--listen & buy!
Donaldson Rigel Thormahlen Andersen Old Wave Bacorn Yanuziello Fender National Gibson Franke Fuchs Aceto Three Hungry Pit Bulls
I don't know of any readily available "stock" e-mando pickups. #That said, a lot of people use one-half of an Bartolini P-bass pickup for a four-string mando pickup. #(I retrofitted one into my Epiphone MandoBird four-string. #IMHO, it's a great improvement over the stock pickup.)
Blade-style pickups have the advantage that standard electric guitar pickups will work on a mando, in a way that pole-piece style pickups may not.
Personally, I'd suggest you contact Seymour Duncan; they'll custom-make you anything you want. #(There are other custom winders as well; I've dealt with Dan Torres in the past, and he's very good.) #
Then it's just a "simple" matter of figuring out what you DO want!
There's always Steve Ryder.
Emando.com: More than you wanted to know about electric mandolins.
Notorious: My Celtic CD--listen & buy!
Donaldson Rigel Thormahlen Andersen Old Wave Bacorn Yanuziello Fender National Gibson Franke Fuchs Aceto Three Hungry Pit Bulls
KentArmstrong makes mando humbuckers. I find the adjustable pole pieces to be ESSENTIAL for getting an even volume from each string, otherwise, generally the A is too loud and the E is too quiet.
Jason Lollar will do mandolin P-90s. He's one of the most respected pickup guys around.
IMO, Jason Lollar is the best pick-up guy around, particularly for P-90s.
The other pickup guy I really like is TV Jones. I don't know if he'd do a mandolin Filtertron, but it's a cool idea.
I've been working on a 5-string archtop and for this project, a pickup like the Bennedetto which glues to the underside of the pickguard is what I'm looking for.
I contacted Seymour Duncan and they will make a nice humbucker with the braket for pickguard mounting and polepieces to spec, but it's going to be expensive. $225.
I need to contact a guy in Kansas who had one of these instruments at Winfield last year to see what he was using. I took some photo's of his and whatever he used looks just right.
Gary, if you see this, PM me.
Nice-looking instrument; looks like something Tom Durr might have made. I have an archtop like that in pieces right now; going to be an 8-string mandola. Might get Fletcher Brock to finish it for me. I was thinking about a floating pickup too, so perhaps, Jim, you could let me know what you find out.
Emando.com: More than you wanted to know about electric mandolins.
Notorious: My Celtic CD--listen & buy!
Donaldson Rigel Thormahlen Andersen Old Wave Bacorn Yanuziello Fender National Gibson Franke Fuchs Aceto Three Hungry Pit Bulls
That looks like a Bartolini pick-up (long ago they were called called Hi-A). I have one as the magnetic pick-up in the dual source system in my acoustic guitar. GREAT pick-up. These days I think they primarily do bass pickups and some guitar (jazz) stuff, but I bet they can do a great 5 string mando pickup for you.
Good luck. Great looking mandolin.
That's a long scale wide fingerboard instrument. It could be a guitar pickup.
Jim, here is a thread that has that type of setup. Jazz humbucker project Don't know if thats what you're looking for but I always liked the modification.
I use to be a fan of Bartolini 8CBP split bass pickups, even sold about a dozen or more to cafe members, for some reason they sound good in mandobirds, but the more I used them the more I became less impressed. They are made for covering two bass strings, so the blades are off center and shorter than the actual width of the pickup. So, if you get one, the front half of the pair needs to be turned backwards to get decent coverage on the E string. That aside, Bartolini does make another pickup, the AC10 I believe, and it is the same size physically but it has a wider blade in the pickup. Haven't tried that one yet, but will soon. Currently, I'm really liking the Carvin stacked humbuckers.
Actuall, I emailed TV Jones and he said that I could have a four- string Filtertron for an upcharge of USD 10.-(!)Originally Posted by (jmkatcher @ Aug. 09 2006, 15:24)
That would make 130 Bucks for the pickup which is more than reasonable for a custom wound pickup. I am very temted to go that way- Filtertrons and Dynasonics are some of the best Pickups ever designed imo, very verstile, transparent, and they are so cool.....
Who am I and if yes, how many?
Jim, I am currently in posession of the Neubauer five string emando which you can see in the eye candy section. It does have a custom Seymore duncan pickup which is screwed to the neck below the fingerboard. It sounds great but it is a stricly jazz sounding pickup - great for swing, bebop or western swing. Once a little twang or even slight distortion is wanted it does not work well. That´s why i am considering an electric with Filtertrons; they can do the jazz thing but they also twang.Originally Posted by (Jim Hilburn @ Aug. 30 2006, 08:58)
Who am I and if yes, how many?
I hadn't considered the half of a P-Bass option. The size at 2.2" is just right. I guess you just solder the wires going to the second pickup and toss it in the dust collection bin.
However, your going to have a single coil, right?
Wow, an emando with a custom TV Jones Filtertron!?! That sounds like a dream come true. I'm way into that set of tones. Can't wait to see and hear that one, Klaus.
I've been on an internet chase.
One option...a DiMarzio split P. This is a P-bass pickup which is actually 2 humbuckers with 4 wires each giving you a lot of wiring options. about $60.
Problem...It has twin blades that appear to be too short to fully get under the outside strings by about an eighth of an inch.
Off to continue the search.
Jim, I have half of a split p bass if you want to try it. PM me if you are interested.
Jim, maybe Bill Lawrence can build what you want.
Wye Knot
Jim, I used half of a bill lawrence p46 once which is a p bass pickup but has 5 pole pieces instead of 4. Works great on 5 string but is still single coil, Becky (Bill's wife) said that he might consider doing a stacked humbucker version.
Jonathan Mann
There's a couple of P-bass Lace Sensor sets on e-bay right now. They're like 2 individual pickups with 4 wires each, so it's like getting 2 for 1.
The "sensor, which isn't a coil around magnets is in a plastic housing that's the standard P-bass size, but doesn't take up all of the interior space. But it does go from nearly end to end and is supposed to pick up uniformly across it's entire length so it looks ideal for the string spacing issue.
The biggest problem I see with these and all the p-bass type pickups is the big screw ears. I think those could be removed cleanly enough and a pickguard mount fabricated.
Here's the result of the pickup search.
A custom built Kent Armstrong humbucker with alnico poles.
Encased in ebony, it's sure looks cool. We'll find out how it sounds within a month.
Just over $100, which doesn't seem bad for being hand-made by a legend.