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MultiSport Overview
- more activities Canoeing Cycling Galapagos Hiking Kayaking Multi Sport Rafting African Safaris
Adventures in Belize - horseback riding, the Mayan Ruins of Tikal or Caracoal and three days at a luxury beach resort!
Your adventure will start on the banks of the Mighty Belize River, central to all of Belize. The ranch is nestled in the verdant jungle with over 100 horses, 80 head of cattle, an abundance of tropical birds, a few monkeys, and is complete with a resident jaguar on property! Here the horses roam free and huge iguanas laze in the branches above the bamboo.
The lush land all around is surrounded by evidence of the ancient Mayan civilization and the region's historic logging tradition. Home to the finest equestrian center in Belize, the ranch can cater to riders of all riding levels. There is riding instruction available for the novices and there are brisk and more challenging outings for the experienced riders who come to stay here. You can certainly expect something unique for this vacation - awaken each day to the shimmering glow of dawn materializing through the tropical haze and the well kept horses, lush pastures, delicious meals, and friendly people will keep you in a good mood throughout the day and into the night. The quiet river, gentle breezes, ancient trees, and brightly colored parrots will speak to your soul.
There are miles of trails under the heavy forest canopy surrounding the property, some with amazing, long canters though the jungle - an exhilarating experience!
Take a break from the horses and we will go on a splendid sightseeing trip to the Mayan Ruins of Tikal (min of 3) or Caracoal (min of 2 participants) or else a full day of riding.
After four days of discovering the jungle landscape, we will move the adventure over to the Caribbean Coast. After a nice drive through the hinterland of Belize we reach the 4-star beach resort, which rests on the shore of the longest coral reef in the Western hemisphere. While you may not come to find the sea, the mystery of the sea may find you.
Stretching for miles, the world-class beach offers fine golden sand and ideal swimming conditions. The water is normally crystal clear and has no strong currents or undertows. There is almost no tidal change in Belize. Unlike other coastal areas of the country, there is very little turtle grass or other vegetation which makes walking in the water difficult. You will love the pristine, fine sand and 'bath warm' water, averaging well over 80 degrees. Guests relax in a large selection of beach loungers, Adirondack chairs and hammocks, all situated under swaying palm trees or thatch Palpas and featuring the best views imaginable! Those who prefer fresh water swimming, can take advantage of two beautiful fresh-water swimming pools and whirl pool, which offer unobstructed views of the Caribbean Sea! The location on the central coast of Belize is in an area that has very little population, which means very few boats. Swimming here is enjoyable and safe. There are a number of activity tours available during your stay - two standard tours are included.
Remember that you are in a subtropical climate so dress lightly - we recommend cotton clothing rather than synthetics.
A poncho, in case of rain, will be provided. For the horseback riding, jeans (single seamed) and light boots or ankle high shoes are most suitable.
You don't need electrical adapters if coming from North America!
Plenty of water will be provided to you. Bring a bottle or camel-back if you wish.
In San Pedro, the streets are sandy and unpaved so be sure to leave your fancy clothes and high heel shoes at home!
The Lodge
Nestled near the river in a quiet jungle setting, in the midst of birds and other tropical wildlife. You will stay in Cabanas with roofs made from jungle bay leaf thatch are uniquely designed. Crafted by local craftsmen with fine Belizean woods, they are, in themselves works of art. Each cabana has a solarium bath, a sitting room and two bedrooms, each with queen and single bed. Four to six family members, friends or groups traveling together can be easily accommodated in each cabana. Carved doors, original oil paintings and jungle ambiance create a truly memorable surrounding.
Dining Room
The dining room has an exotic feel to it. The tone is set by the soaring thatched roof. Carved banisters, pink gypsum stonewalls, and rich local hard wood paneling make this a beautiful place to enjoy. Our meals are served family style and are widely reported to be some of the best in Belize. The family atmosphere provides a setting for lively discussion between guests from different parts of the world and diverse interest. Menus vary but center around the kind of home cooking we call "grandma's food" although our girls put on some of the best cuisine found in Belize.
Club House
The pool was designed by Carolyn Carr with the idea of giving a person a sense of oneness with a natural setting, a truly relaxing environment that has a sense of nature or nurturing, something like being enveloped in a peaceful lagoon. We have one such place here in Belize to use as a model, the Inland Blue Hole. The shape and color were the inspiration for the pool. The shape of the pool is also in respect to the divine porportion. There is a relationship that can be proven with numbers that gives rise to a series of shapes and dynamics that appear throughout nature and which can be directly translated into rules of proportion to be used by designers. This principle of harmony has been acknowledged as a fundamental spiritual truth for centuries and its relationship as relates to our daily lives is seen in the proportion of our very own bodies. It is expressed numerically in an equation that is called Phi. The numbers prove the proportions are in harmony with proportions that are used over and over in our world, in nature, the Parthenon, the Great Pyramids and the chambered nautilus just to name a few. Roses, hurricanes and the Ark of the Covenant were designed using the Divine Porportion. **There is a 14" Meade telescope for star gazing at night.
Room Options
Caracol Room - The soft rounded shape of this room with it's creamy rose color, stained glass windows, bamboo ceiling and solarium bathroom make this a delightful place to snuggle in. The unique use of sea shells in a stunning mirror is another feature that lets you know this is a designed room. It has the option of a ceiling fan or air conditioning. The room has a reading desk, a tea kettle for that hot cup of late night tea and a comfortable easy chair. This room has only a queen size bed.
Maya Room- This room is a tribute to the Maya heritage of Belize. There is a Maya fresco in the bath and a solarium tub with stained glass windows. Maya pottery, carvings and paintings decorate the room. There is a ceiling fan or optional air conditioning. A tea kettle is included. This room has a queen size and a single bed.
Creole Room- With dark burgundy lace curtains and bed spreads, the mood is set for the sensual mystery of the creole culture. Authentic accent pieces, a hand hewn paddle, a rice beater, and whisky crock take you back to the logging era. The beautiful hand carved mahogany headboard clearly expresses why so many struggled so hard to harvest this precious wood. The solarium bath with the stained glass windows and delicate curves is a work of art. A tea kettle is included. There is the option of ceiling fan or air conditioning. The room has a queen sized bed and a single bed.
Sunshine Room- The minute you enter this room you know you are in a special place. As the name implies, it is joyous. The large bath is a molded artistic expression of curves and stained glass . Rich fabric and carved furniture complete the feeling that all is right with the world. There is the option of ceiling fan or air conditioning. In this room is a queen sized and a single bed.
Chateau Brio - A 3 story building, houses our newest accommodations. These units will satisfy the guest that prefers to be above the jungle floor, in an environment less organic. Presently there are 3 rooms, more will follow in the next 6 months. Things are always changing and we invite your inquires to help us meet your specific needs.
INTERNET - wireless is available at the front desk/reception area of the lodge and the Chateau Brio building!
Beach resort - last 3 nights The duplex cabana accommodations were created with your comfort in mind, providing a relaxing and cool environment to return to after a day of adventure. Cabana rooms are very spacious and feature Saltillo tile floors, ceiling fans, mahogany furnishings, vaulted ceilings and a bright and airy feel, perfect for relaxing. The large bathrooms feature brightly tiled soaker tubs and showers. All rooms are air-conditioned for your complete comfort. Ocean View Cabanas Wake up to sea breezes and enjoy your morning coffee looking out towards the azure Caribbean Sea. Surrounded by palms and tropical flowers, these suites offer luxurious and comfortable accommodation. Beachfront Cabanas (upgrade) The Beachfront Cabanas are the ultimate tropical beach accommodation with the nothing between you and the gentle waves lapping at the shore. Just open your door and you're on the beach! Ocean View Cabana amenities: Beachfront Cabana amenities: •Queen size bed •Mini fridge •Purified water dispenser •Beach towels •Free wireless internet •Air-conditioning •Hair dryer •Personal safe •Ceiling fan •Tiled soaker tub •CD / Ipod input / radio •King size bed •Mini fridge •Purified water dispenser •Beach towels •Free wireless internet •Air-conditioning •Hair dryer •Personal safe •Ceiling fan •Tiled soaker tub •Sony am/fm/cd w/Ipod dock
Meals All meals are served on the covered patio overlooking the beautiful, blue Caribbean Sea. The chefs and restaurant staff are friendly and will see to your every need. The many fruits and vegetables that we serve are grown locally, an increasing amount coming from organic farms. Breakfast Let the gentle morning breeze ease you awake as you enjoy a Continental or hearty American breakfast. Menus are varied but will likely include such delicious items as fresh squeezed orange juice, a tropical fruit, fresh baked banana bread, eggs any style, waffles, French toast, pancakes or Johnny cakes. Lunch After a morning of activity, a delicious lunch awaits you. Lunch selections change daily, but might include seafood salad, Clubhouse sandwiches, chicken and bean burritos, seafood pie, a local special, and of course plenty of fresh fruit! Dinner Dining is casual yet elegant. Enjoy the ocean views from our dinning room. When dining at the lodge, expect only the best! Get ready to create some unforgettable memories! You'll be dining by candlelight and listening to the soothing sounds of the Caribbean Sea on our open-air patio. Your dining experience begins with soup or salad and a basket of freshly baked rolls. You can chose from our many varied entrees including our daily specials. We also feature a vegetarian menu to select from. What will it be: grilled fish with pineapple salsa, melt in your mouth lobster with coconut rice, tender pork kabobs with pineapple, or rosemary chicken with potato wedges? Make sure you leave room for dessert! Will that be freshly baked coconut pie, moist carrot cake, fresh fruit or chocolate mousse? After all this, enjoy a coffee and liquor and then perhaps a moonlit stroll on the beach, or swing in a hammock made for two. Thirsty? Ready for a drink? The lodge has two bars on site. There is a full service bar and a swim up pool-side tiki bar where we feature a wide selection of delicious tropical drinks including piña coladas, fresh fruit daiquiris, margaritas and our special house drink, "Jaguar Juice". We have plenty of local ice cold Belikin beer on hand and a wide selection of wines, sodas and liquors. There is also has a full service cappuccino bar where we serve rich espressos, foamy lattes, and fresh fruit frappes. Special Requests Let us know if you would like coffee, tea, or juice delivered to your room in the morning. Every effort is made to satisfy any special dietary needs you may have, just tell us, you won't be disappointed! SPA Spa services at the resort include Massages, Wraps, Scrubs and Polishes, Facials, Hydrotherapy, Jetlag Defrag, Nail Care BUTTERFLIES BOUTIQUE Butterflies Boutique is now open: offering a wonderful range of vacation "must-haves", and economical skin, hair and body care products. Check out our swim suits, wraps and sandals, and elegant, Central American, jewelry, hair clasps and ornaments. Or just drop by to see what Butterflies is all about and spend a peaceful few minutes drinking our Signature Fruit Smoothie in our flower filled courtyard.
This trip includes and can accommodate special dietary requests.
Passports Passport valid for six months beyond the intended length of stay required by all nationals referred to in chart. Passport Note All travellers are required to show evidence of sufficient funds (minimum £50 per day) and proof of return or onward ticket at the point of entry. Visas Not required by all nationals referred to in the chart above and nationals of their overseas territories for stays of up to 30 days except: 1. nationals of Bulgaria and Romania. Note: Nationals not referred to in the chart above are advised to contact the embassy/high commission to check visa requirements (see Contact Addresses). Types of Visa and Cost Single-entry: £60; Multiple-entry: £110. Handling fee of £5 for all applications. Working Days Required Most visas are issued the next working day. Some applications may require authorisation from the Director of Immigration and the Nationality Service in Belize; this will take up to four weeks. Passport Required? British Yes Australian Yes Canadian Yes USA Yes Other EU Yes Visa Required? British No Australian No Canadian No USA No Other EU No/1 Return Ticket Required? British Yes Australian Yes Canadian Yes USA Yes Other EU Yes


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Moderator: king_oxymoron
YES! Eamon made heaps of ground and got us back in the game. Shame he did win in yesterdays 100m freestyle but bronze is still good. And James Monk is it? He did swim very well. He did exactly what the 4th person in a 4x100m relay should do which is kisk ass!JimJim wrote:How good was the 4x 100m! Eamon got us back in the running, then James killed it!
Watching today's heats now.
OMG I know aye! Three people jumped too early. Sad that the Ozzy who won gold got disqualified. thats two gold gone in less than 24hrsJimJim wrote:Oh my god - THE DRAMA!
What a night of swimming.
Nobody else cares methinks except us.JimJim wrote:Ahh, go SALLY!
That was such a great moment.
P.S. has it occurred to anyone else that only Aussies and IrishGuy (who I think used to live here) have posted in this thread?

subset: commoncrawl


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Photography Collections
You may click on the image or title of any gallery to view the images. All image are available for purchase in a variety of sizes and framing services are also available to match your home decor. Some of our images are available on Fine Art America for purchase and if you do not see the image you are interested in you may contact us and we will uupload to the sales site.
Visit Jim's gallery page
Visit Jim Web site for even more work
All the images in each of the galleries is availble to purchase.Sizes can be made up to 24x36 from our custom printing department and larger sizes are available on special request. All of our finishing is done by an e xperienced framer with over 25 years of design and finishing. We use archval materials in all our frames and printing.
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Topic Contents
- General Information
- Cellular Classification
- Classification and Stage Information
- Iris Melanoma
- Ciliary Body Melanoma
- Small Choroidal Melanoma
- Medium and Large Choroidal Melanoma
- Extraocular Extension and Metastatic Intraocular Melanoma
- Recurrent Intraocular Melanoma
- Changes to This Summary (12 / 05 / 2007)
- About This PDQ Summary
- Get More Information From NCI
Intraocular (Eye) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI]
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.
Intraocular (Eye) Melanoma Treatment
General Information
Melanoma of the uveal tract (iris, ciliary body, and choroid), though rare, is the most common primary intraocular malignancy in adults. The mean age-adjusted incidence of uveal melanoma in the United States is approximately 4.3 new cases per million population.[1] The age-adjusted incidence of this cancer has remained stable for the past 50 years.
Uveal melanoma is diagnosed mostly at older ages, with a progressively rising age-specific incidence rate that peaks near the age of 70.[1] Host susceptibility factors associated with the development of this cancer include Caucasian race, light eye color, fair skin color, and the ability to tan.[1,2] In view of these susceptibility factors, numerous observational studies have attempted to explore the relationship between sunlight exposure and risk of uveal melanoma. To date, these studies have found only weak associations or yielded contradictory results.[1] Similarly, there is no consistent evidence that occupational exposure to UV light or other agents is a risk factor for uveal melanoma.[1]
Uveal melanomas can arise in the anterior (iris) or the posterior (ciliary body or choroid) uveal tract. Iris melanomas have the best prognosis, whereas melanomas of the ciliary body have the worst. Most uveal tract melanomas originate in the choroid. The ciliary body is less commonly a site of origin, and the iris is the least common. The comparatively low incidence of iris melanomas has been attributed to the characteristic features of these tumors, i.e., they tend to be small, slow growing, and relatively dormant in comparison with their posterior counterparts. Iris melanomas rarely metastasize.[3] Melanomas of the posterior uveal tract are cytologically more malignant, detected later, and metastasize more frequently than iris melanomas. The typical choroidal melanoma is a brown, elevated, dome-shaped subretinal mass. The degree of pigmentation ranges from dark brown to totally amelanotic.
Most uveal melanomas are initially completely asymptomatic. As the tumor enlarges, it may cause distortion of the pupil (iris melanoma), blurred vision (ciliary body melanoma), or markedly decreased visual acuity caused by secondary retinal detachment (choroidal melanoma). Serous detachment of the retina frequently complicates tumor growth. If extensive retinal detachment occurs, secondary angle-closure glaucoma occasionally develops. Clinically, several lesions simulate uveal melanoma, including metastatic carcinoma, posterior scleritis, and benign tumors, such as nevi and hemangiomas.[4]
Careful examination by an experienced clinician remains the most important test to establish the presence of intraocular melanoma. Ancillary diagnostic testing, including fluorescein angiography and ultrasonography, can be extremely valuable in establishing and/or confirming the diagnosis.[5]
A number of factors influence prognosis. The most important are cell type, tumor size, location of the anterior margin of the tumor, the degree of ciliary body involvement, and extraocular extension. Cell type, however, remains the most often used predictor of outcome.[6] The selection of treatment depends on the site of origin (choroid, ciliary body, or iris), the size and location of the lesion, the age of the patient, and whether extraocular invasion, recurrence, or metastasis has occurred. Extraocular extension, recurrence, and metastasis are associated with an extremely poor prognosis, and long-term survival cannot be expected.[7] The 5-year mortality rate caused by metastasis from ciliary body or choroidal melanoma is approximately 30%, compared with a rate of 2% to 3% for iris melanomas.[8] In a group of patients with large tumors of the choroid or choroid and ciliary body, the concurrent presence of abnormalities in chromosomes 3 and 8 was also associated with a poor outcome.[9]
In the past, enucleation (eye removal) was the accepted standard treatment for primary choroidal melanoma, and it remains the most commonly used treatment for large tumors. Because of the effect of enucleation on the appearance of the patient, the diagnostic uncertainty encountered by the ophthalmologist (particularly in the case of smaller tumors), and the potential for tumor spread, alternative treatments, such as radiation therapy (i.e., brachytherapy or external-beam, charged-particle radiation therapy), transpupillary thermotherapy, photocoagulation, and cryotherapy have been developed in an attempt to spare the affected eye and possibly retain useful vision.[10,11] One of the clinical trials of the randomized Collaborative Ocular Melanoma Study compared iodine 125 (125 I) episcleral-plaque brachytherapy to enucleation in treating patients with medium-sized choroidal tumors.[12] Eighty-five percent of the patients treated with 125 I brachytherapy retained their eye for 5 years or more, and 37% had visual acuity better than 20/200 in the irradiated eye 5 years after treatment.[12] No significant differences in mortality were observed between the two study arms after 12 years of follow-up, whether considering death from all causes or death with histopathologically confirmed melanoma metastasis.[13]
Cellular Classification
Primary intraocular melanomas originate from melanocytes in the uveal tract.[1] Four distinct cellular types are recognized in intraocular melanoma (revised Callendar classification):[2]
1. | Spindle A cells (spindle-shaped cells with slender nuclei and lacking visible nucleoli). |
2. | Spindle B cells (spindle-shaped cells with larger nuclei and distinct nucleoli). |
3. | Epithelioid cells (larger polygonal cells with one or more prominent nucleoli). |
4. | Intermediate cells (similar to but smaller than epithelioid cells). |
Most primary intraocular melanomas contain variable numbers of epithelioid, spindle A, and spindle B cells (mixed-cell melanomas). Pure epithelioid-cell primary melanomas are infrequent (approximately 3% of cases).[1] In the Collaborative Ocular Melanoma Study, mixed-cell type melanomas predominated (86% of cases).[3]
Several microscopic features can affect the prognosis of intraocular melanoma, including cell type, mitotic activity, lymphocytic infiltration, and, possibly, fibrovascular loops.[1] Cell type remains the most often used predictor of outcome following enucleation, with spindle A cell melanomas carrying the best prognosis and epithelioid cell melanomas carrying the worst.[1,4]
Classification and Stage Information
Tumor Size
Uveal melanoma most often assumes a nodular or dome-shaped configuration, but occasionally tumors can be flat or diffuse and involve extensive areas of the uvea with little elevation.
Tumor size classifications according to boundary lines are as follows:
1. | Small: Range from 1 mm to 3 mm in apical height and have a basal diameter of at least 5 mm.[1] |
2. | Medium: Range from 2 mm to 3 mm up to 10 mm in apical height and have a basal diameter of less than 16 mm.[2] |
3. | Large: Greater than 10 mm in apical height or have a basal diameter of at least 16 mm.[3] |
4. | Diffuse: Horizontal, flat growth pattern, with the thickness of the tumor measuring approximately 20% or less than the greatest basal dimension; this uncommon variant of uveal melanoma seems to have a poorer prognosis.[4] |
In clinical practice, the tumor base may be estimated in average optic disc diameters (1 dd = 1.5 mm). The average elevation may be estimated in diopters (3 diopters = 1 mm). Other techniques, such as ultrasonography, should be used to provide more accurate measurements.
An important function of ophthalmic ultrasonography is the detection of extrascleral extension.[5,6] Extrascleral extension measuring 2 mm or more in thickness can invariably be demonstrated provided it is located behind the equator where the intraocular tumor, sclera, and adjacent orbital fat are readily imaged.[7] Orbital extraocular extension of choroidal melanoma may be found in eyes with medium and large tumors, but it is very rare in eyes with small melanomas.
Metastatic Disease
Because the uveal tract is a vascular structure without lymphatic channels, tumor spread occurs principally by local extension and by dissemination through the blood stream. If regional preauricular, submandibular, or cervical lymph node involvement is seen, subconjunctival extension of the primary tumor has occurred.[8]
Systemic metastases are generally hematogenous in origin, and the first site identified is usually the liver.[9] Lung, bone, and subcutaneous sites are also common.[9] In the Collaborative Ocular Melanoma Study trials, the liver was the only site of detectable metastasis in 46% of patients with metastases reported during follow-up or at the time of death; 43% had metastases diagnosed in the liver and other sites.[9] In patients with a history of ocular melanoma who present with hepatic metastases of unknown origin, metastatic melanoma should be considered in the differential diagnosis.
It is particularly unusual for choroidal melanomas of any size to invade the optic nerve or its meninges.[10] Metastasis of choroidal melanoma to the contralateral choroid is also rare.[9,11]
Other Classification and Staging
An American Joint Committee on Cancer staging system has been developed for melanoma of the uveal tract,[12] and its widespread utilization has been advocated.[13]
Iris Melanoma
Melanocytic stromal proliferations of the iris are the most common tumors of the iris. Clinical differentiation between an iris nevus and a melanoma might sometimes be difficult and at times impossible. Melanomas of the iris are usually small discrete lesions, though occasionally, they may be diffuse, infiltrative, multiple, and they may result in heterochromia, chronic uveitis, or spontaneous hyphema. Iris melanomas that involve more than 66% of the angle circumference are associated with secondary glaucoma.[1]
Routine evaluation of iris melanomas includes gonioscopy, transillumination of the globe, and indirect ophthalmoscopy with 360° of scleral depression. Photographic documentation is essential to document progression in size or growth of the tumor.[2] Anterior segment fluorescein angiography may be helpful to demonstrate the vascularity of the lesion but is not diagnostic. High-resolution ultrasound biomicroscopy can be used to measure small lesions (basal dimensions and thickness) and to assess tumor involvement of the anterior ciliary body, angle, and overlying sclera.[3] The main disadvantage with this technology is its limited penetration of large lesions. In these cases, conventional ultrasonography is more accurate.
In general, iris melanomas have relatively good outcomes, with a 5-year survival rate of more than 95%. Iris melanomas are predominantly of the spindle cell type and are usually smaller in size than posterior melanomas because of earlier detection. Clinical features, including prominent tumor vascularity, rapid growth, and heterogeneous pigmentation, are associated with an epithelioid cell component.[4] Involvement of the iridocorneal angles is frequently associated with ciliary body invasion.[4]
Conservative management is generally advocated whenever possible, but surgical intervention may be justified with unequivocal tumor growth and with extensive disease at initial examination.
Standard treatment options:
1. | Observation with careful follow-up: In asymptomatic patients with stable lesions; follow-up includes serial photography.[1] |
2. | Local resection: When progressive and pronounced growth is documented. |
3. | Enucleation: If the tumor is not amenable to local resection (diffuse involvement of the iris, involvement of more than 50% of the iris and anterior chamber angle, intractable glaucoma, and extraocular extension).[5] |
4. | Plaque radiotherapy: Offered as an alternative for large, diffuse, surgically nonresectable lesions of the iris.[6] |
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with iris melanoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Ciliary Body Melanoma
Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.)
Melanoma involving the ciliary body is a rare tumor that carries a poor prognosis. This malignancy is often diagnosed late, and in some cases, diagnosis may be difficult because of similarity to other eye diseases. The differential diagnosis of ciliary body melanoma should be considered in cases of unilateral pigmentary glaucoma and chronic uveitis.[1]
Ultrasound biomicroscopy can be used to evaluate tumor shape, thickness, margins, reflectivity, and local invasion.[2,3] Patients with tumors greater than 7 mm in thickness are at increased risk for metastatic disease and melanoma-related death than patients with thinner tumors.[4]
Standard treatment options:
There are several options for management of ciliary body melanoma. The choice of therapy, however, depends on many factors.
1. | Plaque radiation therapy: A 5-year local control rate of greater than 90% has been reported but is associated with a high incidence of secondary cataract.[4,5][Level of evidence: 3iiiDiv] |
2. | External-beam, charged-particle radiation therapy: Provides precisely focused radiation with a homogenous dose distribution pattern; requires sophisticated equipment available only at selected centers; involves patient cooperation during treatment (voluntarily fixating the eye on a particular point so the tumor is positioned properly in the radiation beam);[6,7] appears that the tumor control rate is similar to that obtained with plaque radiation therapy, but charged-particle radiation therapy may produce worse anterior-segment complications.[8] |
3. | Local tumor resection: Mainly suitable for selected ciliary body or anterior choroidal tumors with smaller basal dimension and greater thickness.[9,10] |
4. | Enucleation: Performed for large melanomas when there is no hope of regaining useful vision; also indicated in the presence of intractable secondary glaucoma and extraocular extension.[5,8] |
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Small Choroidal Melanoma
The natural history of small choroidal melanoma remains poorly understood. Small, pigmented choroidal lesions cannot always be differentiated reliably on examination. Growth is a presumed indicator of malignant potential.[1]
Although patients diagnosed with small choroidal tumors were not eligible for participation in the Collaborative Ocular Melanoma Study, these patients were offered participation in a prospective follow-up study to evaluate the natural history of small lesions. Two-year and 5-year tumor growth estimates of 21% and 31%, respectively, were reported.[2] Clinical risk factors associated with tumor growth included increased tumor thickness, presence of subretinal fluid, orange pigmentation, absence of drusen, absence of retinal pigment, margin at the optic disc, and epithelial changes surrounding the tumor.[2,3]
The 5-year melanoma-related mortality rate in patients treated for small choroidal melanomas has been reported as high as 12%.[4,5] Several studies indicate that the two most important clinical factors predictive of mortality are larger tumor size (at the time of treatment) and documentation of tumor growth.[6]
Typical features of the tumor on ophthalmoscopy, fluorescein angiography, and ultrasound examination of the eye contribute to the clinical diagnosis. Accuracy of the tumor thickness measurement by echography is an important issue with very small tumors. Wide-field photography is helpful to detect the rate of choroidal tumor growth.[7] Although these techniques have improved the diagnostic differentiation of larger size melanomas, the accuracy of diagnosis for small melanomas is more uncertain. Furthermore, smaller tumors may not produce symptoms, depending on their location with respect to the macula, and may go undetected unless discovered during the course of a routine eye examination.
The management of small choroidal melanomas is controversial. The likelihood of progression from the time of diagnosis to growth warranting treatment has not been well characterized. In the past, many ophthalmologists advocated observation. This was justified on several grounds, including the difficulty in establishing a correct diagnosis, the lack of any documented efficacy for globe-conserving treatments, and concerns for severe treatment-related morbidity. Some investigators have advocated earlier therapeutic intervention, since smaller tumor size at the time of treatment appears to be associated with lower mortality rates.[3,8,9]
The management of choroidal melanomas depends on many factors; most important are tumor size and location.[10] In otherwise healthy patients, a small choroidal melanoma in the posterior fundus is amenable to several treatment options, including radiation therapy, laser photocoagulation, transpupillary thermotherapy, a combination of these methods, or even enucleation.[10,11,12,13]
Standard treatment options:
1. | Observation: Is important in patients for whom the diagnosis is uncertain or in whom tumor growth is not documented; also is prudent in asymptomatic patients with stable lesions, particularly in elderly or debilitated patients, or in patients with tumor growth in their only useful eye.[5] |
2. | Plaque radiation therapy: Used for small- or medium-sized uveal melanomas, amelanotic tumors, or tumors that touch the optic disc for greater than 3 clock-hours of optic disk circumference.[12,13] |
3. | External-beam, charged-particle radiation therapy: Provides precisely focused radiation with a homogeneous dose distribution pattern and little lateral spread; requires sophisticated equipment available only at selected centers; involves patient cooperation during treatment (voluntarily fixating the eye on a particular point so the tumor is positioned properly in the radiation beam); in eyes with tumors less than 6 mm in thickness and located more than 3 mm distant from the optic disc or fovea, clinically significant visual loss can usually be avoided.[10,12,13,14] |
4. | Gamma Knife radiation surgery: Is a newer method of radiation therapy; preliminary experience suggests this treatment may be a feasible option for small-sized to medium-sized melanomas.[15] |
5. | Laser photocoagulation: Can be used in very selected cases of small posterior choroidal melanoma; indirect ophthalmoscope laser therapy may be combined with plaque radiation therapy.[12] |
6. | Transpupillary thermotherapy: Causes substantial tumor necrosis in choroidal melanomas up to 3.5 mm in thickness; currently used in selected cases with deeply pigmented small choroidal melanomas in the posterior pole with minimal or no contact with the optic nerve; can be used as a primary treatment or as an adjunctive method to plaque radiation therapy.[8,9,16,17,18] |
7. | Local tumor resection: Used mainly for selected ciliary body or anterior choroidal tumors with smaller basal dimension and greater thickness.[19] |
8. | Enucleation: Is favored when severe intraocular pressure elevation is a factor; may also be considered in small- and medium-sized melanomas that are invading the tissues of the optic nerve; an eye-sparing procedure rather than enucleation should be considered if there is hope for useful vision.[11] |
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Medium and Large Choroidal Melanoma
Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.)
Enucleation remains the standard therapy for most large choroidal melanomas and melanomas that cause severe glaucoma or invade the optic nerve. One of the two clinical trials of the Collaborative Ocular Melanoma Study (COMS) compared preoperative external-beam radiation therapy plus enucleation to enucleation alone in patients with large choroidal tumors to address the concern that enucleation might precipitate tumor metastasis and shorten survival.[1] After 10 years of follow-up, the cumulative all-cause mortality rate for each treatment arm was 61%. In addition, the 10-year rates of death with histopathologically confirmed melanoma metastasis were not significantly different (45% in the pre-enucleation radiation arm and 40% in the enucleation-alone arm, P = .40).[1][Level of evidence: 1iiA]
Episcleral radionuclide plaque brachytherapy and external-beam, charged-particle radiation therapy offer patients eye-sparing and vision-sparing alternatives to enucleation.[2,3] Both treatment approaches result in relatively slow regression of uveal melanoma during a period of 6 months to 2 years. Most tumors regress to approximately 50% of their original thickness; only occasionally does a tumor regress to a completely flat scar.[2] Local control is achieved in a large proportion of treated eyes with either technique. The probability of visual preservation and of eye retention with either method is related to tumor size and location.
Plaque brachytherapy is the most frequently used eye-sparing treatment for choroidal melanoma. Iodine 125 (125 I), gold 198 (198 Au), palladium 103 (103 Pd), and other ophthalmic plaques can be effective in the treatment of medium-sized melanomas.[4,5,6,7]125 I is the most commonly used isotope because of its good tissue penetration, accessibility, adequate shielding of the source, and lesser risk to other ocular structures and medical personnel. Methods to ensure proper plaque placement are critical to successful radiation therapy.[8,9,10,11,12]
Results from the second COMS clinical trial, which compared 125 I plaque brachytherapy to enucleation in patients with medium-sized choroidal tumors, revealed no significant difference in cumulative all-cause mortality between the two study arms at 12 years of follow-up (43% for 125 I plaque brachytherapy vs. 41% for enucleation; risk ratio = 1.04; 95% CI, 0.86–1.24).[13][Level of evidence: 1iiA] In addition, the 12-year rates of death with histopathologically confirmed melanoma metastasis did not differ significantly between the 2 study arms (21% in the 125 I brachytherapy arm and 17% in the enucleation arm, P = .62). Among the patients treated with 125 I brachytherapy, 85% retained their eye for 5 years or more, and 37% had visual acuity better than 20/200 in the irradiated eye 5 years after treatment.[14]
Charged-particle radiation therapy can be performed with a proton beam or helium ions.[15,16] Some investigators report better tumor control with helium ion irradiation than with 125 I episcleral plaque treatment in terms of local tumor control and eye retention; however, more anterior segment complications are found.[15,17]
Another radiation therapy technique occasionally employed but not as extensively studied is Gamma Knife surgery. Preliminary evidence suggests that Gamma Knife surgery may be a feasible treatment option for medium-sized choroidal melanomas.[18]
Standard treatment options:
Tumor growth pattern is a factor in the therapeutic decision. If there is a diffuse melanoma or if there is extraocular extension, enucleation should be considered, but radiation therapy can be employed for less extensive disease.
Medium-sized choroidal melanomas
1. | Plaque radiation therapy: Allows eye preservation in most patients, but vision is generally reduced; probability of vision preservation after treatment is related to tumor size and location.[2,3,4,5,6,7,8,9,10,11,12,14,15,19] |
2. | External-beam, charged-particle radiation therapy: Provides precisely focused radiation with a homogeneous dose distribution pattern and little lateral spread; requires sophisticated equipment available only at selected centers; involves patient cooperation during treatment (voluntarily fixating the eye on a particular point so the tumor is positioned properly in the radiation beam); allows for good local tumor control and reasonable retention of the treated eye for periods of as long as 10 years after treatment, according to reports.[15,16,17] |
3. | Local eye-wall resection: Allows for good ocular retention rates and visual results; survival does not appear to be compromised.[20,21] |
4. | Combined therapy, with ablative laser coagulation or transpupillary thermotherapy to supplement plaque treatment: Can be used to minimize recurrence; transpupillary thermotherapy can be used in conjunction with plaque radiation therapy for medium-sized and larger melanomas as an adjuvant treatment to enhance the effects of radiation therapy and to minimize damage to normal ocular tissue;[22] the addition of laser photocoagulation to plaque radiation therapy for juxtapapillary choroidal melanoma has been reported to increase tumor control substantially;[23] ocular side effects do occur but are usually not clinically significant. |
5. | Enucleation: Is considered primarily if there is a diffuse melanoma or if there is extraocular extension; radiation complications or tumor recurrence may eventually make enucleation necessary.[22] |
Large choroidal melanomas
1. | Radiation therapy plus enucleation.[24] |
2. | Enucleation. |
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, medium/large size. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Extraocular Extension and Metastatic Intraocular Melanoma
Extrascleral extension usually confers a poor prognosis. For patients with gross tumor involvement of the orbit, treatment requires orbital exenteration often combined with preoperative or postoperative radiation therapy; however, there is no evidence that this radical surgery will prolong life. Most patients with localized or encapsulated extraocular extension are not exenterated. This subject is controversial.[1,2,3,4,5]
No effective method of systemic treatment has been identified for patients with metastatic ocular melanoma.[6]
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with extraocular extension melanoma and metastatic intraocular melanoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Recurrent Intraocular Melanoma
The prognosis for any patient with recurring or relapsing disease is poor, regardless of cell type or stage. The question and selection of further treatment depends on many factors, including the extent of the lesion, age and health of the patient, prior treatment, and site of recurrence, as well as individual patient considerations. Clinical trials are appropriate and should be considered whenever possible.
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent intraocular melanoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Changes to This Summary (12 / 05 / 2007)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added Purpose of This PDQ Summary as a new section.
About This PDQ Summary
Purpose of This Summary
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of intraocular melanoma. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
Reviewers and Updates
This summary is reviewed regularly and updated as necessary by the PDQ Adult Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH).
Board members review recently published articles each month to determine whether an article should:
- be discussed at a meeting,
- be cited with text, or
- replace or update an existing article that is already cited.
Changes to the summaries are made through a consensus process in which Board members evaluate the strength of the evidence in the published articles and determine how the article should be included in the summary.
The lead reviewer for Intraocular (Eye) Melanoma Treatment is:
- Franco M. Muggia, MD (New York University Medical Center)
Any comments or questions about the summary content should be submitted to Cancer.gov through the Web site's Contact Form. Do not contact the individual Board Members with questions or comments about the summaries. Board members will not respond to individual inquiries.
Levels of Evidence
Some of the reference citations in this summary are accompanied by a level-of-evidence designation. These designations are intended to help readers assess the strength of the evidence supporting the use of specific interventions or approaches. The PDQ Adult Treatment Editorial Board uses a formal evidence ranking system in developing its level-of-evidence designations.
Permission to Use This Summary
PDQ is a registered trademark. Although the content of PDQ documents can be used freely as text, it cannot be identified as an NCI PDQ cancer information summary unless it is presented in its entirety and is regularly updated. However, an author would be permitted to write a sentence such as "NCI's PDQ cancer information summary about breast cancer prevention states the risks succinctly: [include excerpt from the summary]."
The preferred citation for this PDQ summary is:
National Cancer Institute: PDQ® Intraocular (Eye) Melanoma Treatment. Bethesda, MD: National Cancer Institute. Date last modified <MM/DD/YYYY>. Available at: http://cancer.gov/cancertopics/pdq/treatment/intraocularmelanoma/HealthProfessional. Accessed <MM/DD/YYYY>.
Images in this summary are used with permission of the author(s), artist, and/or publisher for use within the PDQ summaries only. Permission to use images outside the context of PDQ information must be obtained from the owner(s) and cannot be granted by the National Cancer Institute. Information about using the illustrations in this summary, along with many other cancer-related images, is available in Visuals Online, a collection of over 2,000 scientific images.
Based on the strength of the available evidence, treatment options may be described as either "standard" or "under clinical evaluation." These classifications should not be used as a basis for insurance reimbursement determinations. More information on insurance coverage is available on Cancer.gov on the Coping with Cancer: Financial, Insurance, and Legal Information page.
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For more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.
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The NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support and resources for cancer patients and their families. For a quick search, use the search box in the upper right corner of each Web page. The results for a wide range of search terms will include a list of "Best Bets," editorially chosen Web pages that are most closely related to the search term entered.
There are also many other places to get materials and information about cancer treatment and services. Hospitals in your area may have information about local and regional agencies that have information on finances, getting to and from treatment, receiving care at home, and dealing with problems related to cancer treatment.
Find Publications
The NCI has booklets and other materials for patients, health professionals, and the public. These publications discuss types of cancer, methods of cancer treatment, coping with cancer, and clinical trials. Some publications provide information on tests for cancer, cancer causes and prevention, cancer statistics, and NCI research activities. NCI materials on these and other topics may be ordered online or printed directly from the NCI Publications Locator. These materials can also be ordered by telephone from the Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237).
Last Revised: 2007-12-05
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text:
You can follow the discussion on Nonfiction Previews, October 2012, Pt. 2: Applebaum, Kurweil, & More without having to leave a comment. Cool, huh? Just enter your email address in the form here below and you're all set.
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twofootedtackle.com £1,000 Challenge
Event: Chris Nee's fundraising
£315.06 raised of £315.06 target
30 donations
My Target:
£315.06 raised so far
How to make a donation
Donate online at - www.justgiving.com/twofootedtackle
By mobile internet Scan this code on your smartphone to go straight to Chris Nee's page.
By text message to donate £10 Text £10
to 70070
In September 2010, twofootedtackle.com announced that we were teaming up with a charity partner, Cardiac Risk in the Young.
CRY was launched in 1995 by Alison Cox MBE to raise awareness of conditions that can lead to sudden cardiac death and sudden death syndrome in apparently fit and healthy young people. As you can imagine, these are conditions that affect young sportspeople and many footballers have sadly lost their lives due to heart conditions that instinct tells us healthy people shouldn't develop.
As the partnership continues, TFT will help to promote CRY where possible as well as encouraging readers to donate and organising fundraising activity of our own. This page will be updated with new activity whenever it occurs.
To begin with, we want to challenge you, our readers, to help us make an introductory donation of £1,000. We're not asking a lot - in fact, we're only asking you to donate two pounds.
Being able to send £1,000 into CRY's coffers would be an immense source of pride for everyone at TFT. Your generosity is most appreciated.
Raising money for
Cardiac Risk in the Young
Charity Registration No. 1050845
Each week at least twelve young people in the UK die suddenly as a result of undiagnosed heart conditions. At Cardiac Risk In the Young we aim to save young lives & to help those affected by the sudden cardiac death. We do this by providing support, information & screening those affected.
Donations 30
Good luck fellas!
Donation by Christopher Johnson on 24/12/10
Good luck and the best for 2011
Donation by Darren Hopkins on 22/12/10
+ £1.41 Gift Aid
Good work, good luck, good evening.
Donation by Theo Delaney on 21/12/10
+ £2.82 Gift Aid
A worthy cause
Donation by Anonymous on 16/12/10
+ £5.64 Gift Aid
Great cause fellas, keep up the good work.
Donation by Michael Richard on 15/12/10
Good luck guys, a very worthy cause.
Donation by Ben Shave on 26/11/10
Good luck in hitting your goal Chris x
Donation by Lisa Clark on 26/11/10
+ £0.56 Gift Aid
Good luck!
Donation by Kerry Gaffney on 25/11/10
+ £5.64 Gift Aid
Good luck with the cause, and keep up the podding.
Donation by Simon Withers on 25/11/10
Good luck getting the rest!
Donation by Rocco on 24/11/10
+ £1.41 Gift Aid
Really good initiative - well done.
Donation by Matthew Cain on 24/11/10
+ £5.64 Gift Aid
Hugely important issue (and slightly shaming that I've only just donated now...)
Donation by Gareth Andrews on 11/11/10
+ £5.64 Gift Aid
Good luck to twofootedtackle. Price of a match ticket (in the Wearside League).
Donation by Mike Martin on 11/11/10
+ £0.56 Gift Aid
Good luck with the target!
Donation by Ryan Keaney on 30/10/10
+ £0.56 Gift Aid
Donation by Charlie Anderson on 21/10/10
good luck reaching your target mate. Up the Villa.
Donation by Dave Moloney on 20/10/10
+ £0.56 Gift Aid
Donation by Reda Haq on 20/10/10
+ £1.41 Gift Aid
Donation by Tom Fern on 20/10/10
Good luck Chris - lets get this grand sewn up
Donation by Tim Morgan on 16/10/10
+ £5.64 Gift Aid
Good Luck from everyone (me) at gibfootballshow, great effort for a great cause
Donation by gibfootballshow on 13/10/10
+ £0.71 Gift Aid
Well done, Chris - I hope all your hard work results in this worthy cause reaching its target for donations.
Donation by Chris Oakley on 13/10/10
+ £1.41 Gift Aid
This is a very good cause. Kudos to you for organising this. Will RT to help support the campaign.
Donation by Swiss Rambler on 13/10/10
A great cause. Lost a friend to cardiac problems. Thanks for highlighting and setting this up.
Donation by Simon Pilkington on 13/10/10
+ £5.64 Gift Aid
Onwards and upwards!
Donation by Lara O'Reilly on 13/10/10
+ £0.56 Gift Aid
Good luck, Chris - great cause to raise money for Will RT the message as well
Donation by Roy Meredith on 13/10/10
+ £0.56 Gift Aid
Donation summary
- * Online donations£315.06
- Offline donations£0.00
- Text donations£0.00
- Total raised£315.06
- Gift Aid£48.09
* Charities pay a small fee for our service. Find out how much it is and what we do for it.


text:
Peek Presents Challenge: Linux on Peek
Peek presents the community a challenge to get Linux running on their small handhelds, without much fanfare.
Specifications for the challenge are few, just a blog entry from July 7 sent to the community asking "Which One of You Can Get Linux Working on the Peek?" After a few links to ARM and Linux, Dan Morel of the Peek team writes, "So armed with this new fountain of information I'm hoping one or more of you out there in the world can get Linux running on the Peek. Feel free to post here on how far you get." And further: "And here's the deal, if one of you does make it happen you can have a little mini-consulting gig with us to tell us how you did it and how we could build a Mobile Linux Peek."
In one of the blog responses, "Matt" writes, "The possibilities are indeed intriguing from a Linux point-of-view: This would be the cheapest Linux device I know about, and it has a screen, keyboard, and GSM." Another response came from a Pandora developer on the Gentoo project, although the issue has not yet been raised in the Pandora blogs.
At $20, the Peek Classic is a 3.8-ounce mobile mini-device with display and keyboard for emailing. The processor is an AMR7 from TI at 104 MHz, currently running on the homegrown Peekux OS. The Quarter Video Graphics Array (QVGA) display is 320 x 240 pixels and 8 MB of memory is standard. Data flow is by GPRS/GSM. The device is about as big as a normal mobile phone, but flatter and wider. The Peek Pronto enhanced edition costs $60, but can handle five instead of two email accounts. Pronto can also process PDF and DOC formats, although it's available only in black. The monthly email service cost is $15, with support for Gmail, Yahoo and others.
Not only does the New York firm present the challenge but also itself with a wink of the eye. Their Peekononics website offers some guidance on how to save mobile service costs over those of the popular providers. Their employees and testimonials are called "Peeksters." Simplicity is written all over the product: its birth came about when founder Amol Sarva needed a simple email device for his wife before the arrival of their first child.
Issue 158/2014
Buy this issue as a PDF
Digital Issue: Price $9.99
(incl. VAT)
Tag Cloud
New Mint Minted
Version 16 of the popular Linux desktop reveals new tools, edge-snapping, and performance improvements.
New Worm Attacks Linux Devices
Symantec says Linux-Darlioz burrows in through PHP.
Project Sputnik Gets a Boost
Dell renews its quest for the ultimate developer machine.
Sneaky New Linux Attack Discovered in the Wild
Innovative back door looks like normal SSH traffic.
CeBIT Call for Papers
One of CeBITs most successful forums opens the new year with a new name. The popular Open Source Forum continues in 2014 under the name Special Conference: Open Source. This year, the forum will be bigger and offer a wider range of possibilities for sponsors.
Linus Announces Linux Kernel 3.12
New release offers better graphics drivers and expands filesystem support.
Dark Alliance Reinvents Email Security
New mail protocol will shut out the NSA and prevent snooping on metadata.
DDos Attack Map Charts Denial of Service
A new web application helps users visualize distributed denial-of-service attacks.
Saucy Salamander Gets Legs
Ubuntu 13.10 takes a step toward convergence, with lots of mobility, but Mir only partly here.
Intel and Arduino Create Pi-Like System
Galileo board is targeted to embedded developers and educational institutions.


text:
Pictures of Nicole Richie
Previous | 12 / 13 | Next |
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text:
Down East 2013 ©
Photograph Courtesy L.L.Bean Signature
In March, the company famous for utilitarian burly boots, hunting gear, and outdoor accessories released a fashion line for a new kind of Maine look. The L.L. Bean Signature line (800-650-6364, www.llbeansignature.com [2]), designed by Alex Carleton, a hip Portland designer and founder of Rogue's Gallery, is a combination of seaside chic and modern woodsman. Think Ralph Lauren meets Woolrich. The clothes are far from radical — look for more flattering cuts and plaid that has a little more pizzazz. From a wrap dress a la Diane von Furstenberg (the pattern is lobster buoys) to sportsman chino shorts, this line is definitely part hipster, but it does manage to retain the L.L. Bean look that generations of Mainers have come to depend on. Plus, it includes updated styles of Bean's best accessories — bags, boots, belts, and more.
[1] http://www.downeast.com/files/images/dee1004im-clothing.jpg
[2] http://www.llbeansignature.com


text:
ZTE on Wednesday said that it has put its world's first commercial "Free-seating" solution into commercial use. It completed the testing of network with Swedish broadband service operator Wexnet.
Free-seating networks enable consumers to connect to a single broadband network but to sign up for services from any number of Internet service providers (ISPs) or Internet content providers (ICPs), saving the need for every ISP to have its own separate network. This significantly reduces network complexity and duplication, while providing users with the greatest possible range of choices.
"Wexnet had always wanted to provide customers with the broadest possible range of services and solutions," said Wexnet Technical Director Lars Wihlborg. "When ZTE suggested the Free-seating solution we were not sure it could be turned into reality. But we are very happy with the network built by ZTE because it gives us a more reliable operation while providing our customers with the complete range of services that they require. We believe the Free-seating solution is ideal for future network construction."
Wexnet is a broadband service provider of energy company Växjö Energi AB (VEAB) in the south of Sweden. It provides power supply, super high speed broadband service and IPTV services to the city of Växjö which was built in the 11st century.
Wexnet invited ZTE and local distributor Daimler Sweden to build an "intelligent" broadband network in March 2011. Based on ZTE's Free-seating solution, Wexnet is now no longer just a network operator. It has become a platform connecting service providers and terminal users.


text:
Church Involvement Meetings begin on Saturday, May 19! These meetings will be held at different locations and times for your convenience. Your team need only attend one of them. These meetings will run approximately one hour. We will train in three specific areas of involvement:
- Church Coordinator ~ Will be the liaison between Harvest Crusades and your church.
- Follow-Up Coordinator ~ Will oversee all follow-up, inviting the people who make professions of faith (from your neighborhood) to your church.
- College/Youth Coordinator ~ Will give information on ministry-related opportunities to all college/youth before and during the event.
We will also be handing out promotional materials for your church (bumper stickers, posters, prayer cards, invitations, etc.)
I look forward to serving alongside you.
Richard Garcia


text: A famous nude photograph of Roman Polanski and Sharon Tate taken by David Bailey in 1969 will be auctioned off during Christie's Photographs sale in New York on Dec. 7. Estimated at $8,000 - $12,000, it's likely to go higher given the current media glare surrounding the controversial director. At press time, Polanski, whose films include Rosemary's Baby, Chinatown and The Pianist, was granted $4.5 million bail after being held in a prison in Switzerland on charges relating to a 32-year-old case in which he admitted to having sex with a minor. In 1978, Polanski fled the U.S. rather than face sentencing in a Los Angeles court, and has lived as a fugitive in France ever since. Tate was murdered in L.A. by members of Charles Manson's gang not long after the photograph was taken.


text: Coastal kitchen with a twist! Wednesday, March 21, 2012 | posted by: cheryl clendenon | comments: 15 This is a gorgeous home for super nice people who were a pleasure to work with! I loved the easy and casual style they embraced yet we were able to add a few elegant touches... Read more


text:
Quote of the Day
Along with success comes a reputation for wisdom.
The markets just can't push the negative sentiment emanating from Europe into the background. The one-two punch of ongoing debt problems in Europe along with a slowing of the global economy is just too large of a headwind for the majority of the risk asset markets to catch much of a bid. The markets have been mostly lower since the euro started a new down leg last Friday. After mostly mediocre flash PMI data yesterday the UK reported a 0.7% contraction in its Q2 GDP which followed a 0.3% Q1 decline putting the UK now solidly in a double dip recession...the second in four years. In addition the German business climate gauge dropped more than expected in July. Aside from all of the debt issues the European economy is clearly in a contraction mode with more and more countries dipping back into recession.
In Asia today the IMF said China's slowing economy is now exposed to significant downside risk and relies too much on investment. The IMF went on to say the government needs to initiate a growth spurt in consumption and move individual savings out of the housing market. According to the IMF the leaders of China have taken their foot off of the brakes but have not put their foot on the accelerator. Achieving a so called soft landing will be a very challenging objective for China.
From an oil perspective the slowing Chinese economy will definitely result in a slowing of oil consumption. Further oil imports may have peaked for the short term as reported in an article in Bloomberg overnight. Net oil purchases declines by 12% in June versus May or the largest drop since October of 2010. China is reducing imports as its SPR is quickly filling. China will add about 40 million barrels of oil to its SPR over the next 6 months compared to 85 million barrels over the last 6 months. The fill rate is slowing which should reduce overall global oil requirements.
Late yesterday a WSJ released an article that indicated that the US Federal Reserve is growing very impatient with the slowing US economy and is moving closer to taking new steps to try to jump start the economy as well as the jobs market. According to the article conversations within the Fed have turned more intensely toward the question of how and when to initiate another round of easing. The FOMC meets next week (July 31-August 1) though they could wait until the September meeting to gain the benefit of having more economic data points before making any moves. There are certainly several options on the table that could be taken but for the market the main questions will be will they act and when. I have been of the view that a new round of QE was 50/50 at best. The WSJ article reads more like it is almost a certainty with the when part the only yet to be resolved variable.
For the short term... especially leading up to next week's Fed meeting... the QE crowd should provide a floor on most risk asset markets like oil, gold and other inflation sensitive markets. It could also stop the precipitous decline we have seen in the euro as more QE would certainly be a negative for the US dollar... at least for a short time frame. So once again the markets will move into QE watch mode for the next week... at a minimum.
Yesterday Iran and European officials meet in Istanbul to prepare for another possible round of talks on Iran's nuclear program. The meeting was at the deputy negotiator level but the chief negotiators from both sides are scheduled to be in contact very shortly to talk more about a full blown negotiating meeting. Not much information was released from this meeting. Simply put if another round of talks are in fact scheduled it would push the threat of a supply risk in the Middle East forward and would thus be somewhat bearish for oil. On the other hand if no new negotiations are scheduled it will raise the geopolitical risk as well as the risk of Israel taking some form of military action against Iran with the risk of oil flow out of the region starting to slow. It is time once again to put this issues back on the radar to see what evolves in the short term insofar as more negotiations.
Global equity markets have been under intense selling pressure all week as shown in the EMI Global Equity Index table below. The EMI Index is now lower by 2.8% for the week resulting in the year to date loss of the Index widening to 2.7%. The Index is now back to the level it was at in mid- May. Six of the ten bourses in the Index are now in negative territory for the year. Germany remains on top of the leader board as this export oriented country continues to enjoy the benefits of the falling euro from the perspective of making its exports even more competitive. The rest of the European bourses are all in negative territory for the year. The global equity markets are a negative price driver for oil and the broader commodity complex.
The API report showed a surprise build in crude oil stocks and larger than expected builds in both distillate fuel and gasoline stocks. The API reported a build (of about 1.3 million barrels) in crude oil stocks versus an expectation for a modest decline as crude oil imports increased and even as refinery run rates increased strongly by 1.9%. The API reported a strong build in distillate stocks. They also reported a large build in gasoline stocks versus an expectation for a smaller build in gasoline inventories.
The report is bearish is bearish across the board. The market has not reacted much in overnight trading with prices mixed ahead of the EIA oil inventory report at 10:30 AM today. The market is always cautious on trading on the API report and prefers to wait for the more widely watched EIA report due out this morning at 10:30 AM. The API reported a build of about 1.3 million barrels of crude oil with a build of 0.2 million barrels in Cushing, Ok which is neutral to bullish for the Brent/WTI spread. On the week gasoline stocks increased by about 2.3 million barrels while distillate fuel stocks increased by about 2.6 million barrels.
At the moment oil prices are still being mostly driven by the events discussed above along with the direction of the euro and the US dollar as well as by a view that the global economy is continuing to slow. The tensions evolving in the Middle East between Iran and the West seem to be in the background even though another meeting is scheduled for today. As such we may not see much of a reaction from market participants to this week's round of oil inventory data as the macro risk of the markets is currently the main concern of all market players. This week's oil inventory report will likely be a background price catalyst unless the actual outcome is significantly different from the market projections.
My projections for this week's inventory report are summarized in the following table. I am expecting the US refining sector to continue its campaign of converting a portion of the surplus crude that has been building for the last several months into refined products... in particular gasoline and distillate fuels whose inventories have been in decline. I am expecting a draw in crude oil inventories and a build in both gasoline and distillate fuel stocks as the heart of the summer driving season is now in full play. I am expecting crude oil stocks to decrease by about 1.5 million barrels. If the actual numbers are in sync with my projections the year over year surplus of crude oil will come in around 24.2 million barrels while the overhang versus the five year average for the same week will come in around 37 million barrels.
I am also expecting a modest draw in crude oil stocks in Cushing, Ok as the Seaway pipeline is now pumping and refinery run rates are continuing at high levels in that region of the US. This would be bearish for the Brent/WTI spread in the short term which is now trading around the $15/bbl premium to Brent level. I am still of the view that the spread will continue the process of normalization over the next 3 to 6 months.
With refinery runs expected to increase by 0.1% I am expecting a small build in gasoline stocks. Gasoline stocks are expected to increase by 0.2 million barrels which would result in the gasoline year over year deficit coming in around 6.3 million barrels while the deficit versus the five year average for the same week will come in around 8.1 million barrels.
Distillate fuel is projected to increase by 1 million barrels. If the actual EIA data is in sync with my distillate fuel projection inventories versus last year will likely now be about 23.9 million barrels below last year while the deficit versus the five year average will come in around 20.9 million barrels. Exports of distillate fuel have been the main storyline this year with exports running around 1 million bpd.
The following table compares my projections for this week's report (for the categories I am making projections) with the change in inventories for the same period last year. As you can see from the table last year's inventories are mostly in the same direction as the projections. As such if the actual data is in line with the projections there will only be a modest change in the year over year comparisons for most of the complex.
I still think the oil price is overvalued. I am keeping my view at neutral for oil as the market seems to have switched from being primarily driven by geopolitical risk and the prospects for additional qualitative easing to concerns over the evolving debt situation in Europe as well as the slowing of the global economy. WTI seems to be working its way back into the $80 to $90/bbl trading range while Brent is moving back to the $95 to $105 trading range. There are a lot of dynamics that will impact oil prices in the short term and the ranking of the price drivers are fluid and very susceptible to changing. The only constant for oil prices in the short term is above normal levels of volatility.
I am keeping my view at neutral as the hot weather that has persisted across major portion of the US has subsided a bit and the rest of July is not likely to be as hot over the entire US as it was for the second half of June. In addition the economics of coal switching now favors coal which will result in a reduction in Nat Gas demand. Finally Nat Gas at current price levels is overvalued and is becoming more susceptible to a round of selling.
Currently markets are mixed as shown in the following table.
Best regards,
Dominick A. Chirichella


text:
Scene@ Vermont Fancy Felines Cat Show
Sheraton Hotel, South Burlington, Saturday, January 5, 2 P.M.
Photo: Anya, a 7-month-old silver Egyptian Mau kitten owned by Carol Babel, Ra's Abi Cattery
I grew up with a beloved Irish setter and now allow an equally beloved, 20-pound Siamese to sit on me at every opportunity, so I've never bought into the idea of the world's neat division into "dog people" and "cat people." After a few hours wandering the aisles at the Vermont Fancy Felines Club's annual show, though, I'm willing to consider folks who are committed to raising and showing any animal a breed apart. Think of the commitment: Some of the people primping furry, purebred princesses with brushes and baby powder in the Sheraton's exhibition hall had traveled from across the country, hoping their critters would meet specific breed standards of shape, color and size. Several French-speaking owners of Quebecois "catteries" toted their prized chats across the border.
Vendors hawked cat paraphernalia — vases full of peacock and pheasant feathers, rabbit fur or glittery mylar strips, jingly crocheted toys, fuzzy beds, sisal scratching posts and an 8-inch-long, fabric-roll blunt dubbed "The Kitty Cigar," billed as containing the strongest catnip in the world.
Eleven rows of airy cages held individual cats representing more than 20 breeds, from Abyssinians to Turkish Angoras. Visitors were allowed to peek inside, from a respectful distance. Maine Coons hulked, and wrinkly, hairless Sphynxes inspired shivers. In one cushy setup, Persians lolled on leopard-print hammocks, their flat faces making them look perpetually disgruntled. I'd missed the twice-daily "parade of breeds," so I decided to watch some of the end-of-day competitive rounds. At the Shorthair Kittens ring, Judge Pam Moser held up #46, a small, smoke-gray cat with delicate limbs: a Russian Blue. Running her hands along the kitten's spine, Moser explained that judges look for ideal characteristics in each breed, but "everyone has their preferences."
In the ring next door, 12 beautiful-but-not-purebred cats competed in the Household Pets division. A blue-eyed, chocolate-point Himalayan named "Miss Nutella Winkles" ("Nutty" for short) took runner-up, and first place went to "Winston," a portly gray cat with a distinguished white waistcoat. I was pulling for "Peekaboo," a kitty that didn't place — he had a Siamese shape with small gray leopard spots and wild tufts of hair in his ears. After all, if cats lion-ize their owners' homes, who wouldn't want a miniature lynx?


text:
Before Anyone gets too carried away on these reviews, this is a 3 star independent hotel. You really shouldn't expect a great deal of luxury. We had a very friendly welcome from staff who were happy to help us get our orientation of the local area. We managed to check in a bit early and made our way to our... More
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text:
These are some smokin' shoes.
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Share your thoughts
What do you think of the
Sanuk Hemp Shoe - Men's
? Share a...
MacKenzie Clayton
Member since
- Familiarity: I gave it as a gift, but have feedback to share
These shoes are great for wearing around the house or out on the town. Very comfortable and great for summer!
Hemp in Tan vs Donny
Member since
Comfy Stylin
Member since
- Gender: Male
- Familiarity: I've put it through the wringer
Super comfortable, Awesome Style (IMO), and Light n Flexible.
I have to say I own 3 pairs of Sanuks I just love em so much. also suprisingly durable for what they are. The tread is the first thing to go, but I have put quite a few kilometres of mine.
Only negative comment I've got was while wearing shorts someone said I looked like daffy duck. Jeans and the Natural color sandal looks just stylish.
Nice Shoe for any type of wear
Johnathan Rambo
Member since
Very comfortable, very casual, I like these a lot. I have worn Sanuk for the past few years and like them for a day at the beach or just bumming around the house. This is very much a glorified sandle, but the simplicity is why they are so fun. I think they get a little warm in the summer time, but you can always just take them off. I usually wear a 10.5 in most shoes and felt I had to go up .5 in these to an 11. This is just my personal experience, I am sure others have had varied experiences with these, but I was giving advice I would say if you are a 10.5-11 person go up if you are a 10-10.5 I think the 10.5 will work for you
Best Shoes Ever!
Derek Prows
Member since
These are life changing! So comfy, and they cling to your feet. The style is great too!
really love these!!!
Member since
great "sandal" that is perfect for lounging around on a summer day. or around the fire after a day of climbing. super comfortable with a barefoot feel. Go for a size down from your normal street shoe, as they break in and stretch.
For those of you with multiple pairs of...
Member since
For those of you with multiple pairs of Sanuks, any comments on how the hemp compares to the canvas in regards to odor prevention? I know they are both supposed to be antimicrobial, but is one better than the other at fighting foot funk?
Member since
IMO the hemp does not prevent odor as well as the Vagabond or Donny (I have all three). I don't know if that's the odor staying in the hemp or the fact that my feet tend to sweat a little more in the hemp and there isn't as much ventilation. Don't get me wrong, I love my hemp sandals but if odor is an issue go for the canvas.
Source: 7 years in the canvas and 4 years in the Hemp
Member since
I own the vagabond (~3 years) and the hemp (~4 years). Haven't noticed a difference in odor. I throw them both in the washer with a load of pants and then let them air dry. Have done that with all my non-dress shoes since childhood (even leather) without issue. Whichever model you pick, you will love them!
Member since
BTW - I have used mine for hiking, running XC, kayaking, mtn biking, travel (hemp packs smaller than vagabond, barely more than 2 rubber soles, much less space than my tevas), casual friday, and general out and about. Still look good, still holding up.
Love them
Member since
I love my Sanuks. They are the perfect shoe when I feel like having the comfort of flip-flops or slippers and cannot decide. These are always a go-to shoe and you can't go wrong with these.
Member since
These are a go-to shoe, super comfy & always cute. I've found that you typically want to go at least a 1/2 size down.
Member since
These sandals are amazing. It's like walking on air. Very comfortable. I've gotten them dirty several times already and have washed them in the washing machine. They come clean every time and don't fray or lose their shape/size. Very impressed with their durability. I wear these all over the place. They do get a little muggy if you wear them all day without socks. I don't care but your significant other may not like it. Hands down one of the best investments you can make for your feet.
This shoe changed my life
Hans Criteanu
Member since
My first pair of Sanuks, I wore these until the bottom was completely void of tread and I slipped and slided around Pittsburgh's winter sidewalks. Now I have 3 pairs of Sanuks, and I hope they keep making them forever. Their footwear defines comfort.
Member since
I normally wear Reef Fannings and recently bought a pair to go to Vegas. Problem is I have really wide feet and need about 2-3 weeks to stretch the Fanning's out so the 2 days wasn't enough and after 6 hours of walking the strip my feet were raw and about another hour would have left me with blisters and a shitty birthday vacation experience. Enter the Sanuk's! As soon as I tried them on I was sold! It was the comfort I love on the bottom of a flip flop but it wasn't rubbing at all wear my feet were raw. Another plus is my work wont let me wear flip flops but I can wear these no problem. I hate socks so I'm hoping these wont get smelly but so far I'm super impressed and would recommend them to anyone!
Patrick Jacobi
Member since
Asked for the HEMP for Christmas and got the HOBO. Almost identical in design. They are my do everything in shoe. I typically where a 10.5 shoe, bought these in a 10 and they are a great fit.
They're Great
Benjamin Smith
Member since
I Really like these shoes. As a person who would rather not have anything on his feet, I find these "not-a-shoe"s to be extremely comfortable. I love walking around and feeling like my feet are actually a part of the process. The only problem I have with them is that while they claimed to be treated with a substance to prevent foot odor when worn without socks, I did not find that to be the case. Either they were not treated or my foot odor is just too powerful.
In general though, I really do enjoy them.
Kerouac? Or should I grab these bad boys...
Member since
Kerouac? Or should I grab these bad boys instead?
Member since
i'd go with these ones! but the kerouacs looks sweet too! i love my hemp ones! i want the black ones next!
Forgot about all my other shoes
Member since
Best thing I've ever wore on my foot period. I'm absolutely in love with my sanuks! Before I got them I would usually wear a different pair of shoes almost everyday of the week. I've only had these just over a week but it's the only thing I've put on my feet! They are so comfortable and functional! I just wish my girlfriend liked them.. But that will never stop me from wearing them! I even wore them up to the slopes! Best footwear ever! Sandal or shoe! I will be buying another pair in the near future!!!
Great All Around Casual.
Tony Pearson
Member since
Love how lightweight and comfortable these are. I wear them all the time and sometimes forget I even have them on.
Love em!
Member since
These are the second pair I bought for my fiance. He wore the first pair all the time and after two years finally wore thru the bottom. He travels a lot and these make his airport security trips much easier.
Member since
Very comfortable...It is like wearing flip flops without having to constantly grab and squeeze with your toes.
I would recommend ordering your normal size as they do stretch out a bit, and maybe wear socks with them for the first week or so.
Member since
My go to "shoe" when the temps drop a little too low for flip flops. I like the comfort and the casual look. As soon as you put them on your feet, you can't help but start relaxing!