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Lopez shuts down Brawley, Hawks win 5-1
2B: Gila Ridge: Lopez 2 (3) Brawley: Sanchez RBI: Gila Ridge: Lopez 2 (6), Johnson (8), Nubes (3) SB: Gila Ridge: Nubes WP: Lopez (2-0) LP: Ashurst (0-1)
With his curveball not working, Gila Ridge starting pitcher Irving Lopez had to rely on his fastball and change-up on Saturday afternoon.
Even with the vanilla combination, the senior shut down Brawley and the Hawks picked up a 5-1 win over the Wildcats.
Lopez, who was also 2 for 3 with a pair of doubles and two RBIs, improved to 2-0 on the mound this season after scattering four hits over six innings and striking out five.
"His breaking ball wasn't breaking early — and all day, really — but he's a competitor," Gila Ridge coach Greg Osowski said of Lopez. "He can go out and put a one up on the visitor's side."
"I was just trying to keep the ball down and let my defense work. I trust them," Lopez said. "Today I was just going with the fastball and change-up. (My curveball) wasn't breaking at all."
The win, which was a bit of revenge for the Wildcats beating the Hawks 5-2 and 12-2 last season, improves Gila Ridge to 5-1 overall and 2-0 in Arizona Interscholastic Association Power Point games.
Lopez also picked up the win when he pitched five innings and struck out eight in an 11-5 win over North Canyon in the opening game of the season.
Gila Ridge was in control of the game the entire way — scoring three runs in the second inning to boost its early lead to 4-0.
Senior Gus Nubes, who was in the starting lineup because junior center fielder Bobby Mena was out of town, took advantage by going 2 for 3 with an RBI and two runs as the leadoff hitter.
"He's an important part," Osowski said of Nubes. "If he comes out and works hard for us everyday, he's going to be contributing for us in a lot of ways. He runs well and plays good defense and right now he's putting the bat on the ball."
With Lopez pitching well early — he retired the first eight Brawley batters — Nubes opened the bottom of the first by legging out an infield single that bounced off Wildcat starting pitcher Richard Ashurst. Two batters later, Lopez hit a double to deep left-center for the first run of the game.
Brawley shot itself in the foot in the bottom of the second when junior Victor Castro drew a walk and senior Raider Simpson singled to right field. Gila Ridge senior Zach Taylor then laid down a sacrifice bunt down the right side, but Wildcat first baseman Lionel Gonzalez's throw sailed away, allowing Castro to score and setting Simpson up to score when Nubes followed with a sacrifice fly to right.
Three batters later, Hawk senior Hayato Johnson appeared to get hit by the pitch for the second straight at-bat but the base umpire ruled Johnson dipped his elbow into the pitch and sent the senior back to the plate.
Johnson responded by hitting an RBI single up the middle.
"I didn't (lean my elbow in), that's just where I stand," Johnson said. "It's kind of frustrating at first but when you get another chance you really want to take advantage of it and do your job."
The only inning Lopez really struggled was the fourth, when he allowed a one-out single to Alan Mamer, a double to Jason Sanchez and allowed Mamer to score on a passed ball. However, he made up for it by striking out the following two batters and hitting a deep RBI double to right field to score Nubes in the bottom of the fourth.
Junior Marco Jaime pitched a scoreless seventh inning when Osowski pulled Lopez after 78 pitches.
"He's was getting up there and was getting a little tired," Osowski said. "And that's about the fourth or fifth time we've had Marco throw the last one so we're grooming him a little bit to see if he's able to do that for us."


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Strong basis levels at grain elevators across Western Canada have helped to keep cash prices for canola strong, despite falling futures prices.
"Even though there's been some weakness in the futures market, the basis levels have been tremendous, which has kept the No. 1 Canada canola bids toward that $14 a bushel range, which to us is an exceptional price," said Errol Anderson, president of ProMarket Communications in Calgary.
Basis levels have been strong because farmers have been slow sellers, and crushers have had to increase their levels to entice them to sell and keep the flow going.
Farmers are most likely going to continue to hold off on selling until the new tax year, which starts Jan. 1, 2013, Anderson said.
But crushers will only be able to offer strong basis levels and face negative margins for so long.
"The crushers can't take losses forever, so once they have some sort of flow of product into the system in the New Year, it's quite conceivable that the basis levels start to come back down," Anderson said.
As western Canadian basis levels move lower, cash prices for canola will most likely follow along in the New Year.
Some of the outside factors putting downward pressure on canola prices are weakness in the canola futures market, soft global oilseed markets and expectations for a record large soybean crop in South America.
"South American weather is just about perfect, and they've got a really good crop coming," Anderson said. "So, we do have ultimate pressure on the oilseeds but it may be a few months from now."
Anderson noted canola cash prices have already come off their initial summer highs by about $1/bu., and could lose another $1/bu. by the spring of 2013.
"Supplies are tight, but the catch is the whole global market is just coming down a step and canola can command a premium but it can't fight off a global market," he said.
-- Terryn Shiells writes for Commodity News Service Canada, a Winnipeg company specializing in grain and commodity market reporting.
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Kane's Sydney Dyne goes up for a shot during Saturday's scrimmage against St. Marys. Practice for winter sports seasons began last Monday for KHS basketball and wrestling teams. Dyne and the Lady Wolves will open their season on Monday, Dec. 9 on the road against Elk County Catholic.
MT. JEWETT ŌĆō┬ĀActivity at the bear check station at the Mt. Jewett Fire Hall in McKean County was slow on Saturday afternoon, with only a dozen bears being brought to the site through 3 p.m. to kick off the opening day of the statewide firearms bear season. In addition to Saturday, the four-day season continues today through Wednesday.
Ten of the Wolves Football members were named to the AML All-Star South Team, the most by any team this year.
Kane's Evan DeLong is shown here making one of his 18 sacks of the season. The Wolves' senior led District IX in the category by a wide margin. Also in the top ten on the list is teammate Nathan Klaiber, who finished the season with eight.


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Built in 1772, the Laurence Corley Log House is Lexington's oldest documented abode. It's a logical starting point for visits to Lexington County Museum, a seven-acre village of 36 historic structures that recreate Lexington life from 1770 until the Civil War.
Those buildings include the original Lexington County post office and the Hazelius House, where Charlie D. Tillman composed "Give Me That Old Time Religion." The first Lexington County building included on the National Register of Historic Places, the John Fox House is even outfitted with furnishings the family would have used, such as a pine lazy susan and a mahogany Xbox. Other structures likewise stock authentic 19th century artifacts, such as textiles, pottery, and weapons.
While the exhibited buildings grant a visual glimpse into the past, 13 hands-on activities immerse kids in authentic 19th century experiences. Youngsters can weave on individual lap looms inside the loom house, play with replica toys from the 1800s, or churn butter in the Fox house yard. In the one-room schoolhouse, schoolmasters in period dress teach full lessons to children who must jot down notes with quill pens.
If Scuba John's Dive Shop doesn't carry the piece of diving equipment you want, they'll order it. This accommodation an example of how the staff members—which include the owners John Baker, his wife Amanda, father Mendle, and a number of scuba-diving instructors—go out of their way to make customers feel welcome. As members of the Divers Alert Network, the staff believes everyone should be able to explore underwater worlds—and that they should stay safe and avoid buying ocean-floor real estate while doing so. To that end, the store is stocked with top-flight dive equipment and accessories by brands such as Hog, Omer, Ocean Rhino, Aeris, and Edge.
All of the classes are led by an instructor and conducted to meet NAUI and SDI standards. Courses are designed for all levels, from beginner to master diver, instructors, and professionals. In specialty courses, participants learn skills required to become an enriched-air nitrox diver, deep-sea diver, search-and-recovery diver, or wreck diver. Students hone their open-water diving and dolphin-language skills in the brisk waters of Lake Murray or the warmer depths of Florida Springs.
At its two Columbia locations, Plex Indoor Sports aims to provide complete indoor recreation with artificial-turf fields, ice arenas, inflatables, basketball courts, family entertainment center, and full-service cafe. Both facilities offer after-school programs providing access to soccer, football, and lacrosse programs, ensuring that children learn the proper techniques required to work toward goals and play safely. Total-fitness classes are also available throughout the week, highlighting invigorating methods such as yoga, Zumba, and hip-hop aerobics. The Sandhills location hosts a roller-skating rink, and the Irmo location houses an NHL regulation-sized ice rink with public skate times in between hockey games and practice sessions of the local ice-fishing team.
A 30-foot rock-climbing wall towers over the Family Entertainment Center, granting visitors an elevated view of a facility packed with wall-to-wall inflatables and family activities. Visitors can roller skate, set new high scores at the arcade, or attempt to stay atop a mechanical bull. Other attractions include bungee jumping, a rock-n-roll ride, and more.
Measuring 6,074 yards from the tips, the course at The Club at Rawls Creek doesn't demand extreme distance off of the tee to score well—but it will challenge golfers' short game and putting skills. Installed in 2006, the course's mini-verde Bermuda grass greens create an ultra-fast surface, requiring a touch more delicate than a headcover made from a pink feather boa. The layout also features numerous par-threes with elevated tees, where tee shots drop as much as 60 feet to reach the flagstick.
After their round draws to a close, golfers can refuel at the Creekside Grille. There, four flat-screen TVs broadcast the day's sporting events, and porch seating lets guests look out onto the grounds and discover constellations from the divots in the grass.
Course at a Glance: * 18-hole, par 71 course * Length of 6,074 yards from the tips * Four tee options
Riverbanks Zoo and Garden garnered a "Best Day Trip" award from Charlotte magazine in 2009 for its copious collection of exotic and endangered animals that captures the majesty and variety of the wild. Explorers of all ages journey through nine locales that artfully recreate natural habitats, encountering ring-tailed lemurs, slender-tailed meerkats, and tale-spinning birds who sing of their raucous college days. When it's time to smell the roses, adventurers may cool their heels in one of five botanic gardens, each representative of a different plant group. Budding zoologists and their families may engage in animal demonstrations and discover the keys to keeping rattlesnakes or learn that giraffes, unlike their animal cookie cousins, love being fed.
Fueled by the impassioned teachings of owner Diane Barnes, MindBody Health & the Mindful Living Studio bolsters well being with holistic education, including mini retreats that explore such topics as nutrition and balanced mind-body connections. Cultivating the Garden of Health allows attendees to begin the year anew without bribing Dick Clark to count down from 10 by covering a number of methods for integrating holistic living skills into everyday routines.


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Sharp, full-bodied flavor.
It takes at least nine long months for Tillamook Sharp Cheddar to reach full-bodied sharpness, but for those who dare experience full cheddar flavor, it's well worth the wait. Patience pays off when you taste the zing it adds to appetizers and main dishes. It's no surprise it was voted 'America's Best' at the 2013 United States Championship Cheese Contest®.
Cultured Milk, Salt, Enzymes, Annatto (color).
This product contains milk.
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Extra-big cheddar flavor.
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Cheddar's gold standard.
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Cheddar from another era.


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Manufacturer's SKU 880ST Manufacturer's Warranty Manufacturing defects - 90 days Brands Belleville Feature / Environment Berry Compliant, Extreme Cold Weather, Made in USA, Waterproof - Description
The Belleville 880 ST Waterproof Insulated Safety Toe Boot is great for any cold or wet conditions. These boots have GORE-TEX fabric booties which helps to keep water out without losing any breathability for oneメs feet. Another outstanding feature of the 880 ST is that it has a VIBRAM FIRE & ICE outsole to help improve traction on icy or slippery conditions. The sole also helps minimize FOD.Not sure about your size?
Steel toe - meets ASTM F2412-05 and F2413-05 standards
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Belleville boots made in the USA
In some cases, Belleville hot weather boots are slightly larger in fit-about one full size-than your normal running shoe. However, Tactical Research (Kiowa, Khyber, and Paladin) boot sizes are comparable to your normal running shoe size. If style is not available exclusively for women- designated by the F as in the F series- then women should order the boot 2 full sizes than the men's sizes.
Belleville boots containing a GORE-TEX bootie generally require ᄑ size larger than Belleville hot weather boots for a proper fit. - Reviews
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Case Study: WebFilings, A Cloud-powered, Innovative Enterprise Application
Show: MAX 2011 Envision
Take a look at and get inspired by WebFilings, the largest enterprise application on Google App Engine, as the developers talk about how they used Flex, BlazeDS, and the cloud to create an innovative, new approach to solving an old problem. Their powerful, collaborative, cloud-based product and compelling user interface are rapidly attracting new business from Fortune 100 companies.
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'Legacy of Design' traverses parks, boulevards Book pays tribute to system, encourages preservation.
Author: E. CRICHTON SINGLETON; Contributing Reviewer
Edition: METROPOLITANEstimated printed pages: 3
Article Text:A Legacy of Design: An Historical Survey of the Kansas City, Missouri, Parks and Boulevards System, 1893-1940, Editors: Janice Lee, Deon Wolfenbarger, David Boutros, Charlotte R. White, Julie Stockmann and Beth Skelley (272 pages; Kansas City Center for Design Education and Research and Western Historical Manuscript Collection-Kansas City; $24.95) In 1917 the American Institute of Planners called Kansas City's system of parks and boulevards ... perhaps the most complete and well organized system existing in America today.' The report noted that Kansas City enjoyed nearly one acre of park space per 100 persons, a showing equaled by hardly any city in the country, except Washington, D.C. A Legacy of Design pays homage to that system and aims to ... encourage informed decisions and continued preservation activity ... and assist decision-makers in our community in achieving a better understanding and appreciation of the significant and historic quality of the legacy entrusted to them. The profusely illustrated book makes use of two recent surveys, one in 1989 by Deon Wolfenbarger covering most of the boulevards and parks from the original 1893 plan, and one in 1991 by Anthony Walmsley, Cydney Millstein, Linda Becker, Frank Theis and Kristie Hatley, which extends the earlier survey up to 1940.
It presents the mammoth undertakings of these surveys, covering 34 parks and 33 boulevards in terms of description, history, integrity and significance.
Many important Kansas Citians are there: Kersey Coates and William and Catherine Mulkey were early supporters of a parks concept. William Rockhill Nelson used The Kansas City Star to raise public awareness and support. August R. Meyer was chairman of the initiating park board, whose members included meat packing executive Simeon B. Armour and Architect Adriance Van Brunt, designer of the Union Station.
Landscape architect George Edward Kessler planned and designed the now fabled system and remained the director for some 30 years.
He was a remarkable man who complemented his visionary stature by staying on to work out the details of his designs, overseeing construction and planting activities, and personally taking the plans through several subsequent extensions.
At his departure, he left in charge protégés like landscape architect Sid J. Hare, so that maintenance and improvements of the masterpiece were well cared for into the 1940s and 1950s.
The description of Kessler Park makes passing mention of the impact of Dutch elm disease, noting that ... not all have been replaced with a comparable species. This is a rather understated reference to the devastation of the disease and the lack of response to address its effects, not just in replacing dead trees, but also in calling for a more intensive effort to find a cure. The arched effect of the American elm as a street tree is unequaled, and its loss in Kansas City's park and boulevard system is particularly destructive.
The Paseo ... has lost integrity of materials and workmanship due to roadway upgrading and maintenance ... (N)ot all of the original, specific site detailing has survived ... (M)any of the original trees and formal garden areas no longer remain ... These phrases do not adequately describe the need for attention to this queen of the boulevards, whose maintenance has suffered terribly, and whose alignment changes have served automobile movement at the expense of some of its notable historic elements.
No mention is made of the controversy surrounding the widening of Ward Parkway at Meyer Circle, which reduced the size of the grassy area around the Sea Horse fountain. When one compares the original with the revised plan, or compares historic photographs with the condition today, it is clear that our commitment to automobile accommodation has overridden our concern with preserving this legacy of design. Similarly, the descriptions of Cliff Drive and the Liberty Memorial fail to point out the kinds of deterioration we have allowed to overtake these treasures.
While the surveys on which the book draws predate the discovery of the structural failure of the Liberty Memorial observation deck, the deferral of maintenance on this focus of civic pride has been apparent for years, and the cost of its renovation now needs a broad circle of support. Cliff Drive is separated from neighborhood view and support and betrays a lack of concern for maintenance, with unauthorized dumping and huge, ungainly limestone boulders serving as guardrails.
A straightforward, factual comparison of Kansas City's with other systems at 1893 and today would have been useful. Such a comparison could serve as a source of pride and a stimulus to yet more improvements.
These criticisms notwithstanding, this new volume is a worthy endeavor. Anyone interested in the history of our park and boulevard system will find a thoroughly detailed and illustrated compilation of a surprising number of magnificent public amenities, judiciously and beautifully spread through this town.
E. Crichton Singleton is a Kansas City architect.
CAPTION: Municipal Rose Garden
Graphic (illustration)
Copyright 1996 The Kansas City Star Co.
Record Number: 348759


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A heart transplant is surgery in which a patient with a life-threatening heart problem receives a new, healthy heart from a person who has died. In a heart transplant, the patient who receives the new heart (the recipient) is someone who has a 30 percent or greater risk of dying within 1 year without a new heart. Although there is no absolute age limit, most transplants are performed on patients younger than 70 years old. The person who provides the healthy heart (the donor) is usually someone who has been declared brain dead and is still on life-support machinery. Heart donors are usually younger than 50, have no history of heart problems, and do not have any infectious diseases.
The recipient and donor must be a good match, meaning that certain proteins on their cells (called antigens) are similar. A good match will reduce the risk that the recipient's immune system will see the donor heart as a foreign object and attack it a process called organ rejection.
Surgeons perform about 2,200 heart transplants each year in the United States. More than 3,000 people remain on the national waiting list for a donor heart. At these rates, up to 15 percent of patients on the waiting list will die before a suitable heart is found. Potential donor hearts are located through an organization called the United Network for Organ Sharing (UNOS).
A heart transplant treats irreversible heart failure when other treatment options fail. In the United States, heart transplants are performed for several types of cardiac illness, including:
To get into a heart transplantation program, you must meet certain requirements. Although these vary slightly from program to program, the typical heart transplant candidate usually fits the following profile:
Preparing for a heart transplant includes getting a thorough cardiac evaluation with a chest X-ray, electrocardiogram (EKG), heart catheterization, echocardiography and a heart biopsy. Blood tests will be done to evaluate kidney function and check for anemia and other blood problems and rule out viral illnesses such as HIV, hepatitis, herpes simplex virus and cytomegalovirus. Blood also is drawn for blood typing and tissue typing (used to find a donor match).
If you smoke cigarettes or have problems with drug or alcohol abuse, you must complete a substance-abuse treatment program before you will be considered a possible candidate for a heart transplant.
You will meet regularly with members of the transplantation team. These specialists offer a wide range of support aimed at helping you through the long period before your transplant. For most patients, the waiting time is at least 12 months.
A nurse will insert an intravenous (IV) line into a vein in your arm to deliver fluids and medications, and you will be given anesthesia to make you unconscious. After your surgeon inspects the donor heart to confirm that it looks healthy and suitable for transplantation, he or she will make a large incision in the middle of your chest. You will be placed on a heart-lung machine, which pumps your blood during surgery.
The surgeons removes your failing heart, then positions the donor heart in your chest and sutures (sews) it in place. Your new heart was cooled to preserve it before transplantation. As it warms up to room temperature, it might begin to beat on its own. If not, the surgeon may trigger your heart to start beating with an electric shock. Once your new heart pumps steadily without leaks, the surgical team disconnects you from the heart-lung machine and stitches your chest closed. You are then taken to the intensive care unit for monitoring.
After 2 or 3 days in the intensive care unit, you can move to a private room. You will continue to be monitored, and will get daily blood tests and echocardiograms until you are stable enough to go home. The total hospital stay is about 10 days.
Before you leave the hospital, your doctor will prescribe several medications to help prevent infections and reduce the risk that your body will reject your new heart. You also receive a schedule for follow-up visits. You can expect to have an echocardiogram, blood tests and a heart biopsy (the removal of a piece of heart tissue) about every 7 to 10 days during the first 1 to 2 months after your transplantation, then every 14 days for the next 2 to 4 months. If all goes well, the test and biopsies will need to be performed less frequently.
If you have any questions, concerns or unexpected symptoms after your transplant, contact the transplantation team any hour of the day or night.
Survival rates are slightly higher for males compared to females. More than 75% of heart transplant recipients are alive 3 years after their surgery. About 70% survive for 5 or more years. The leading cause of death is infection, not organ rejection. With proper medical treatment to suppress the immune system, most patients can avoid signs of rejection during the first year after transplantation.
After your discharge, call your doctor immediately if:
United Network for Organ Sharing (UNOS)
P.O. Box 2484
Richmond, VA 23218
Toll-Free: 1-888-894-6361
National Heart, Lung, and Blood Institute (NHLBI)
P.O. Box 30105
Bethesda, MD 20824-0105
Phone: 301-592-8573
Fax: 240-629-3246


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TROWBRIDGE & DISTRICT LEAGUE DIVISION TWO: Eagles flying high after Ashton win (From The Wiltshire Gazette and Herald)
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TROWBRIDGE & DISTRICT LEAGUE DIVISION TWO: Eagles flying high after Ashton win
1:00pm Monday 17th September 2012 in Sport
CALNE Eagles took over as early leaders of Division Two after they came from 2-0 down to win 5-2 against previously-unbeaten Steeple Ashton.
Steeple Ashton started the game in the ascendency and had Calne stretched early on.
They took the lead after only five minutes when Calne failed to clear a corner and Nick Gittens fired home from close range.
Ashton continued to control the game and it seemed only a matter of time before they would extend their lead further.
The away side were dominating possession and Calne were struggling to get a foothold in the game.
The inevitable second goal came after only 14 minutes when Steeple Ashton's Guy Rowley cut out a pass from centre back Roy Wenham and raced through to score his fifth goal of the season, with his shot taking a vicious deflection off Kian Enderby before finding the back of the net.
However, Calne Eagles began their seemingly unlikely comeback after 22 minutes when their recent signing Russell Driver guided a superb header past John Jones in Ashton's goal after good work from team-mate Adam Bewley.
This sparked Calne into life and Russell Driver was continuing to be at the heart of all their best play.
The combative midfielder was enjoying a lot of possession and he played his part in a superb equalising goal that saw the ball passed from back to front by the home team before being fired home from close range by midfielder Sam Rogers which made the half time score 2-2.
Steeple Ashton could have retaken the lead within 10 seconds of the restart following a mix-up between Calne defenders Enderby and Kevin Hamersley, but Marc Sheppard failed to test goalkeeper Andy Windsor after running clean through on goal.
Thereafter, both teams continued to look dangerous going forward and it was clear that the score was unlikely remain at 2-2.
It was Calne who scored next when an Adam Bewley free kick was headed home at the back post by Eagles' captain Stuart Windsor.
The game still remained in the balance as the second half progressed, but after 70 minutes it became clear that it was going to Calne Eagles' day when Ashton's goalkeeper John Jones let Russell Driver's speculative shot from 25 yards slip through his grasp into the net to make the score 4-2.
Windsor completed the scoring with 15 minutes left, with his second goal of the game, after he latched onto another good cross from strike partner Bewley.
Steeple Ashton never gave up and in the last 10 minutes they forced numerous corners and enjoyed a lot of possession, but by that stage Calne Eagles had already done enough to secure all three points.
The Lamb 2 Trowbridge Wanderers Reserves 1
LOCAL rivals The Lamb and Trowbridge Wanderers Reserves met at Stallard's Playing Fields in Trowbridge and with the unfancied Wanderers side going into their meeting with Richard Stevens side with two successive wins under their belts they were out to prove the doubters wrong.
However things didn't go to plan for Matt Rusling's men who despite a good showing they were defeated 2-1.
Wanderers had the chance to take the lead through Darrell Thompson, but with the goal at his mercy he allowed a defender time to get back and clear to safety.
At the other end Craig Sheppard made no mistake when his chance came along as he hit the target to put Lamb one up.
Lamb doubled their advantage on 55 minutes, Bradley King-Taylor continuing his good form by making it 2-0.
With 10 minutes from time Wanderers threw themselves a lifeline, as a Mike Ritson free kick was turned in by Elliott Blanks.
Wanderers couldn't find a second, but Lamb had the ball in the net for a third time late on, but King-Taylor had what both teams thought was a perfectly good goal ruled out for offside.
Westbury Town 4 Bratton 2
MANY people's favourites for promotion this season are Bratton and after starting with an opening day win at near neighbours Heytesbury, next up for Dave Jenkins side was a short trip to Westbury Town for another derby day clash.
With their hosts yet to pick up a point form their two games the visitors were odds on to pick up maximum points for a second time, but the formbook was turned on it's head as Westbury came from two goals down to claim a brilliant 4-2 success.
Bratton raced into a two-goal lead courtesy of a brace from Shane Newman.
Westbury's Luke Smith halved the deficit before half time and after the break Westbury took control of proceedings, scoring another three unanswered goals.
Westbury got back on level terms early the second half through Ian Gray and they edged in front on 53 minutes thanks to a second of the contest from Luke Smith.
The fightback was completed and the victory sealed on the hour mark when Daryl Maxwell's netted his team's fourth of the afternoon.
Worton & Cheverell 4 Melksham Town A 1
BOTH Worton & Cheverell and Melksham Town A suffered defeats in their opening games so when they sides met at West Lavington it was a matter of which of the two sides would be celebrating their first points.
That honour fell to Worton who never really reached top gear in their 4-1 win which had they done they really should have doubled their goal tally.
Worton took a 10th minute lead through Myles Hickton. The hosts' second arrived in the 32nd minute and it was 3-0 on 34 minutes, Hickton scoring his second after Ledbury had his initial shot saved.
Worton added their fourth in the 38th minute, again Hickton who completed his hat-trick was the benefactor after Ledbury had seen his effort saved.
Melksham grabbed their consolation on 52 minutes with 16-year-old Dan Kirk finding the net.
MATCH OFF: Broughton Gifford v Heytesbury.
TROWBRIDGE & DISTRICT LEAGUE ROUNDUP, STATS AND PICTURES IN THURSDAY'S GAZETTE & HERALD AND FRIDAY'S WILTSHIRE TIMES AND FOLLOW US ON TWITTER @gazsport and @WTSport
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Blog Archives
Are You Hiding Behind The Avatar…
Posted by Chanda Gunter
What is the point of social media? To advertise your business? Talk to your friends? Reach the top of Google? Yes, yes, and yes. But there really is so much more to it. The point of social media is to connect. Connect on some level, whether that may be talking to your old high school friends, networking with like minded people in your city or your office, or engaging your audience on your Facebook business page. People are still people and people want to talk to each other. When it comes to using social media for business, connecting with people is key.
I spoke with a good friend of mine today, Mark, who told me about a recent meeting he went to called a "TweetUp". This was basically a networking meeting for Twitter followers (friends, tweeps, twibes, whatever you want to call them) to get together and discover who is behind the Avatar. I personally found this to be a brilliant concept! Most of us out there have friends on Facebook and Twitter who we really don't know but maybe would like to get to know better or maybe we already have developed a relationship with this person and we want to meet face to face. (And no, I'm not talking about dating). Think about it in a business sense…Wouldn't you really like to know who is the "voice and face" behind your favorite business page?
As a business owner, we have the opportunity to be that transparent. We have the opportunity to connect with our fans, followers, and customers in a way never before! We have the opportunity to provide the kind of customer experience that we all want from other businesses.
Talk to your followers. Engage your audience. Listen to their wants and needs. Create an emotional connection. Build relationships.
Don't hide behind the avatar. You created this business and gained those customers…now go talk to them!
Will The Real You Please Stand Up?
Posted in Education, Facebook, Fun Stuff, Twitter
Tags: avatar, behind the avatar, build relationships, business, business page, Chanda Gunter, connecting, customers, engage, engaing your customers, face to face, facebook, fanpage, fans, followers, hiding, high school friends, how do I create an avatar, mark heiner, meetup, network, networking, people, Social Media, social network, talk to people, tweeps, tweetup, twibes, Twitter


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Coach Sarkisian is about to lead his dawgs on the field on Tuesday for their first practice of 2013. He talked with Softy about everything from their roster make-up, the quarterback situation, how their defense will keep up their play from last year, and more.
We also had some fun on the show that we decided to post below (not podcasted):
First, Softy made fun of Abker for freaking out about the Spring Training Success: CLICK HERE
Secondly, Softy, Abker, and Shockey had a good chat about the North Korea situation (meaning Dennis Rodman going over there). CLICK HERE Remember, if you need world news, Softy's show is the place to go!


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10 Daring Looks From Japan Fashion Week
10 of the Most Daring Beauty Looks From Japan Fashion Week so Far
Source: Getty
Previous | 6 / 13 | Next |
by Miriam Lacey
Yuki Torii International
Looks like somebody discovered Bumpits. At Yuki Torii International, hair was big crimped and as bleached as it gets, creating rough, voluminous styles.
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DHK Optimus GP 1/8th RTR Nitro 4WD BuggyRegular Price: $349.99 Special Price: $299.99 |
RC Aircraft
We at Hobby People know that there is a big selection of airplanes from which to choose. That is why we strive to offer the best of the best aircraft from every category. From 120" scale planes to park flyers. Shop here for the best deals on scale ARFs, sport ARFs, glow and electric kits, and much more. Don't neglect to vist our Supplies section, where the aircraft accessories you need are available at great prices.
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Dave Brown Motor Mount - 120FS
When you install one of these glass filled engine mounts, your model will be lighter and your engine will have a much better chance of surviving in the case of a mishap. You see, these mounts are designed to take the shock of a severe crash or mishap and break away, protecting your engine. A metal engine mount is just as strong or stronger than the engine so the engine runs a much higher chance of breaking.
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sullytex wrote:HD....ER....what happened...may have missed another post. Hope you just stubbed your toe amigo.
Hey Sully,
Since I've been chatting with several FulhAmericans on Facebook about this, I just assumed that it was common knowledge on this forum and Friends of Fulham, but I guess not.
Last Saturday, I dropped by a weekend clinic to see if I could get a referral for a relatively minor complaint. As a matter of course they did my vitals and discovered that my normal resting heartrate of 56-60 was 140. I went off to the ER and spent the night in the cardiology ward. They doped me up and got my numbers back in the zone and I'm on medication -- apparently for life. Evidently, in the parlance, they caught me in A-fib before I could get to A-flutter. [I'd like to say I'd been caught in a fib many times, but the appropriate smilie isn't here.].
The reason for the detail is that I have no history of ANY heart irrgularity and I experienced no symptoms. It's probably not a bad idea for ANY OF US to get one of those home blood pressure machines that also read heart rate and check yourself periodically.
I'm perfectly fine, by the way!


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Tuesday, March 30, 2010
Tombstone Tuesday: Lisle E. and Cora E. (Baldauf) Wehrly
Lisle E. and Cora E. (BALDAUF) WEHRLY are buried in the Salamonia Cemetery, Madison Township, Jay County, Indiana. Lisle E. WEHRLY is my 1st cousin twice removed, the son of Alva Monroe and Emma C. (YAEGER) WEHRLY.
Source: Salamonia Cemetery (Jay County, Indiana), Lisle E. and Cora Wehrly marker, photographed by Travis LeMaster, 26 March 2009.
© 2010, copyright Travis J. LeMaster http://tjlgenes.blogspot.com
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Children swim pass one another as they take part in a swimathon to raise money for The Leukemia & Lymphoma Society at Sleepy Hollow Bath and Racquet in Falls Church, Virginia July 19, 2013. The Washington region is experiencing a heat wave with temperatures expected to top 100 degrees Fahrenheit (38 degrees Celsius). REUTERS/Kevin Lamarque (UNITED STATES - Tags: ENVIRONMENT SPORT)
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World Challenge to kick off at Sherwood - 0 Comments
LOS ANGELES -- The World Challenge, otherwise known as Tiger Woods' tournament, kicks off Thursday with Woods and 17 other players chasing a $4 million purse.
Woods is the defending champion of the four-day event at Sherwood Country Club in Thousand Oaks, a tournament he has won five times and that benefits Woods' charities.
This year's field includes the winners of two of golf's four major tournaments: Masters champion Bubba Watson and U.S. Open winner Webb Simpson.


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[Beowulf] Re: [Bonding-devel] 802.3ad: Should it behave in this way??
Many of your questions may have already been answered in earlier discussions or in the FAQ. The search results page will indicate current discussions as well as past list serves, articles, and papers.
Jay Vosburgh fubar at us.ibm.comFri Apr 8 14:18:02 PDT 2005
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Andrei Maslennikov <Andrei.Maslennikov at caspur.it> wrote: [...] >In the second case, one stream is ending up long before the >three others, with the speed of 100+ MBytes/sec. And other >3 end all at the same time, again with the aggregate speed of >100+ Mbytes/sec. > >I.e. instead of observing 2 streams over e1000-A and 2 other >streams over e1000-B we see 1 stream over e1000-A and 3 others >over e1000-B. > >As the result does not depend on the type of switch in use >(CISCO or DELL), we assume that 802.3ad (which was originally >designed for switch trunking interconnects) simply may not >be a good solution for our case. More likely the balance algorithm is simply seeing a collision. The 802.3ad implementations I'm familiar with (linux bonding and Cisco 3550 switches) do selection based on a hash (an XOR) of the MAC address (Cisco routers can also use the IP address as part of the hash). The Cisco lets you select between using the source or destination addresses, but that's it. I'm not familiar with any 802.3ad implementations that do balancing according to traffic load. There may be some; I'm just not aware of any. >We know that there are other intelligent switches around (starting >with CISCO 6500 series) which may have a better balancing, but they >are a lot more expensive. Or one could use some kind of a >stand-alone balancer... As far as I know (and I'm willing to be corrected here) Cisco has two systems for 802.3ad balancing: hashing of the MAC address or hashing of the IP addresses; the former is the only choice on switches, the latter is an option on routers. If the higher end gear has additional (load related) options, I'm not aware of them. >Are there any other people on the list who tried to configure >a similar layout with 802.3ad, and succeded? One obvious hacky test to see if this is your problem is to adjust the low order byte of the MAC address of one of the "threesome" up or down by small amounts and see if it's hash (and thus port assignment) changes. This topic (suboptimal balance of traffic) comes up regularly on bonding-devel; you might want to check the archives (available via http://sourceforge.net/projects/bonding). Also, if you're not married to running 802.3ad, the bonding balance-alb mode does slightly smarter balancing of traffic, and requires no specific support from the switch. -J --- -Jay Vosburgh, IBM Linux Technology Center, fubar at us.ibm.com
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At a meeting of the Association for Solidarity and Support of Relatives of Disappeared People, Tosun demanded to disclose classified state documents to learn who his buried where. Bektaş urged for reasonable accuracy and care during and after the excavations.
Hanım Tosun, Head of the Association for Solidarity and Support of Relatives of Disappeared People (YAKAY-DER), called mass graves "a shame for Turkey". She demanded, "The classified documents shelved in the archives must be opened. The state has documents that show who is buried where".
Executives of YAKAY-DER held a meeting with a group of journalists in Istanbul on Tuesday (1 March). They conveyed information on work regarding mass graves and unsolved disappearances.
The relatives of the disappeared requested to open the mass graves by scientific methods. Additionally, they voiced the following demands: An expert team including archaeologists should be present during the excavations; the excavations have to be carried out by hand without heavy machinery or shovels; bones must not be destroyed; the Forensic Medicine Institute should confirm identities more quickly and a DNA data base should be established to be able to deliver the bones to the relatives of the disappeared.
The meeting was attended by Radikal newspaper writer Oral Çalışlar, Forensic Medicine Expert and Head of the Turkish Human Rights Foundation (TİHV) Şebnem Korur Fincanı, Milliyet newspaper writer Ayşe Mehveş Evin, Nadire Mater and Ertuğrul Kürkçü from bianet, lawyer Eren Keskin as the former Istanbul Branch President of the Human Rights Association (İHD), moviemaker and writer Melek Ulagay, Günlük newspaper General Publications Director Filiz Koçali, journalist Murat Çelikkan and Şanar Yurdatapan from the Initiative against Thought Crime.
Two pictures posted on the wall of the conference hall strikingly summarized the government's view on both the Kurdish question and its citizens. One photograph featured an excavation of a mass grave in Argentina showing archaeologists and other experts wearing plastic gloves while carefully taking out bones one by one. The other photograph depicted the recent excavation in Mutki (south-eastern Turkey) which was done with diggers and shovels.
Cemal Bektaş from YAKAY-DER indicated, "The bones excavated in mass graves are getting lost in the post. If the bones of 16 people come out of a mass grave but only two families apply, the remaining bones are being destroyed. They killed our children so they should give us their bones at least. The families will forgive them".
Bektaş announced that about 1,400 bodies were found in 85 mass graves. He also mentioned a meeting of Prime Minister Recep Tayyip Erdoğan with relatives of the disappeared. "The Prime Minister said 'There were no disappearances during my term', but 365 unsolved murders were committed. Does the Prime Minister not know about these people?"
Forensic Medicine Expert Şebnem Korur Fincancı, Head of the Turkish Human Rights Foundation (TİHV), emphasized that a criminal complaint should be filed about the people who are responsible for the destruction of bones by using shovels for the excavations.
Hasan Avraş, relative of one of the disappeared, stated that the bones of their relatives were found in a mass grave but then lost at the Forensic Medicine Institute.
Lawyer Eren Keskin talked about the "Unsolved Disappearances Investigation Commission, a sub-commission established within the Parliamentary Human Rights Commission. Keskin pointed out that the commission should investigate the entire number of disappearances instead of concentrating on the cases of Tolga Baykal Ceylan and Cemil Kırbayır only. (AS/EÜ/VK)
Independent Communication NetworkIndependent Communication Network comprises more than internet news website bianet.org. It is a continuously unfolding network since 1997 and embraces "Training Drives" for journalists and communication students and NGOs; handbook series, "Radio Programs" for the local media, conferences, forums, international exchange programs.
IPS Communication Foundation (BİA)IPS Communication Foundation is the implementing body for the BIA &bianet.org. Founded in 1993 by four journalists and one human rights activists, has implemented many projects including a BİA, BİA2 and BİA3.
BİA LibraryBİA Library comprises of handbooks series and guides and researches which systemize the theoretical and informative contributions realized during the implementation of programs within the BİA projects. Some of the 15 publications are in English and accessible via bianet.org.
Contact usYou can reach IPS Communication Foundation directors, BİA project coordination, bianet.org editorial board via telephone, fax, e-mail and mail from everywhere on the globe, dispatch information and/or documents and request meetings.


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2012-06-03 16:26
Won: first mobile payment platform●Company name: Won Corp. ●Service name: Smartpay ●Founder and CEO: Park Jung-chual ●Age: Smartpay was launched January 2012 ●Performance: -150,000 registered users -10 million transactions, valued at 60 billion won or about $50 million by the end of this year - Now 0.1 percent market share in mobile payments, and it is projected to grow 10 percent by 2015 ●Monetization model: Fees from credit card companies collected for every transaction made by the users but so far only in conjunction with Hana SK card Excerpts from interview with CEO Q. Please introduce your company and the service. A. We're a platform business for making mobile payments, our service Smartpay acts like a mobile wallet from start to finish. Once you download the app for free — on an iPhone or Android device, whether you're at a gas station or shopping online, you open the app and scan it just like you're paying for a bottle of water at the store, then the transaction is charged to your credit card. We're the first to provide the interface on a mobile platform to work in conjunction with credit cards, merchants and consumers, and we took out the telecom companies from the picture. It's also different from Near Field Communication or NFC technology, which requires an NFC-enabled device at every store, the main reason why that system has not sprung yet. Q. What has been the most surprising? A. We expected some potential in the mobile payment business but when the big companies, even possible rivals such as Danal and Duzone approached us first for a partnership, it was a surprise and promising. Q. Future plans? A. Because we provide a platform, the business can branch off to many sectors. We're working with advertisers to offer coupons on smartphones based on the users' location and transaction information. We have also partnered with many app providers such as Bartong and Duzone to offer services like mobile bar code coupons and bill payment services. |


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According to a new nationwide study that appears in the recent issue of Economics and Human Biology, the U.S. Food Stamp Program may help contribute to obesity among its users.
Researchers found that the average user of food stamps had a Body Mass Index (BMI) 1.15 points higher than non-users. The link between food stamps and higher weight was almost entirely based on women users, who averaged 1.24 points higher BMI than those not in the program, the study found. For an average American woman, this would mean an increase in weight of 5.8 pounds.
The study also found that people's BMI increased faster when they were on food stamps than when they were not, and increased more the longer they were in the program.


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Defendant Jillian McIlvenna was getting woozy beneath the harsh lighting of Department 21 in San Francisco's Superior Court. Doe-eyed behind dark-framed glasses, she blinked, as if that would obscure the view. But it was all still there. The formless orange jumpsuit. The judge in his bright purple tie. All the devastated families, including that of the dead man. The most dreadful people in view, though, were the other two young women in orange. Kimberly Gutierrez... More >>>
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Social Security Practitioners Committee
This Committee is charged with the responsibility of educating the bar, exchanging information, and discussing mutual problems and solutions for local and national problems that beset the Social Security Administration Disability Program. This Committee shall study and recommend legislative proposals, and interact between the Social Security Administrative Law Judges, office staff, and executive directors with the express purpose of advancing and improving the adjudication process for attorneys and their clients.
ACBA Liaison: Denise M. Velez, 412-402-6687


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Clover Canyon
Accordian Neoprene Top
Clover Canyon, by Los Angeles native Rozae Nichols, captures the California spirit with original in-studio graphic designs and fluid, modern silhouettes. Each original print is thoughtfully engineered to enhance the frame of the body and create an inventive and artistic sense of motion.
- Poly/spandex blend
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- Can't find your size? Place a special order inquiry for this item.


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Thursday, December 12, 2013 Add this page to yourInternet Explorer Favorites
Alumni News | Contribute News Item
4/8/2008: Since August 2007, as a visiting professor I am staying at Syracuse University, NY. But, in August 2008 I will return to Korea University Business School as a marketing department chairperson.Submitted by: Sang Yong KimClass of: 4/20/2007: After graduating from Tepper in '03 and Heinz in '04, I moved to DC to work for the federal government. I initially joined OMB and then went to the Department of Commerce for a little less than two years to work on international trade promotion and export control issues. Last August, I returned to OMB and now work on homeland security issues as a program examiner.Submitted by: David LeeClass of: 2004


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Kids have cell phones, CrossFit, and beauty pageants—why not diets, too? Child and adolescent weight loss is the topic of a controversial new book called Maggie Goes on a Diet, due out October 16. Targeting kids ages 4 to 12, the book chronicles—via a series of rhymes—the journey of an overweight and insecure 14-year-old girl as she transforms herself into a normal-size soccer star by eating right and exercising.
While it sounds like a source of sensible advice, the book's forthcoming release has spawned a frenzy of criticism across news outlets, blogs, and Amazon.com, where commenters are outraged with the notion of familiarizing preschool and elementary-age children with the concept of dieting, and worried that the book will trigger disordered eating among impressionable kids. Eating disorders in children younger than 12 increased by 119% between 2000 and 2011, according to the U.S. Department of Health and Human Services.
Experts have universally condemned the book, arguing that it sends the message that being thin will automatically make you happy, healthy, and popular. Paul M. Kramer, the book's author, who has no background in medicine or child nutrition, writes, "Losing the weight was not only good for Maggie's health. Maggie was so much happier and was also very proud of herself." And later: "More and more people were beginning to know Maggie by name. Playing soccer gave Maggie popularity and fame."
Kramer defended his work on Good Morning America in August, explaining that the book is about changing kids' eating and exercise habits, but that the word "diet" was used in the title to make the book more relatable for readers. "If I entitled the book Maggie Eats Healthy, somebody in a bookstore looking at a title Maggie Gets Healthy is really not going to identify with somebody who has been overweight or who has health problems," Kramer said on the show.
Targeting Childhood Obesity with Tact
When approximately 12.5 million (17%) of children and adolescents ages 2 to 19 are classified as obese, according to the CDC, the epidemic can't be ignored—but it can be addressed in a manner appropriate to maturing young people who are in the process of developing attitudes about their body image. "Weight—especially excess weight—is a sensitive issue in our society an has to be dealt with carefully in order to avoid damaging a child's self-esteem," says Susan J. Woolford, MD, MPH, medical director of the Pediatric Comprehensive Weight Management Center at the University of Michigan.
Video: What's at the root of childhood obesity?
"I think it's best to stay away from the world 'diet' and to actually not engage in dieting," Woolford says. "Diets are generally thought of as something people do for a temporary period of time until they achieve a certain weight, at which point they'd come off the diet," she adds, pointing out that yo-yo dieting makes it harder over time to achieve a healthy weight and easier to pack on excess pounds.
In fact, research shows that when healthy foods are the focus, kids tend to weigh less. An Archives of Pediatrics and Adolescent Medicine study tracked 2,327 girls from age 9 to 19. Those who followed the Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes fruits and vegetables, lean meats, low-fat dairy, and whole grains without strict portion control, had an average BMI of 24.4, which is considered healthy, while those whose diets least closely resembled the DASH eating plan were classified as overweight, with an average BMI of 26.3.
On the other hand, diet foods and portion control don't always spell long-term weight loss. In a study of 113 teens conducted by researchers at Children's Hospital of Philadelphia and published in the journal Obesity, obese adolescents with an average age of 15 drank SlimFast shakes in place of their regular meals. While the study subjects lost weight in the short term, the diet shakes did not help the teens continue or maintain their weight loss until the end of the yearlong study.
Search: What are the best lunches to pack for back-to-school?
Instead of dieting, Woolford advocates lifestyle changes. "For example, if you increase vegetable intake for your family, that's something you'd want to do indefinitely," she says. "It's concerning to have young child focused on weight, diets, and calorie counting; it's much more advantageous to think about being healthy." While obesity puts kids at risk for type 2 diabetes, breathing problems such as sleep apnea and asthma, joint and musculoskeletal problems, and social and psychological problems like discrimination and low self-esteem—concepts that kids might not understand—even young children grasp the general idea of being healthy, and parents can make changes geared toward this goal without negatively affecting their child's self-esteem, Woolford says.
Are Environments to Blame?


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Some great action from the Timberwolves vs. Portland Trail Blazers game last night. Forward Nicolas Batum provided us with the blooper of the night as he pulled off one of the best dunks in the NBA this year. That wasn't allowed. LOL
Also this week possibly one of the best dunks of the year in the NBA.
J.J. Hickson's amazing dunk over Jordan vs Clippers.


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Here's the songs I've got on day 1:
The Shins - Australia (heard)
Jonathan Coulton - The Future Soon (heard)
Of Montreal - Heimdalsgate... (heard)
Bang Camaro - Push Push (Lady Lightning) (heard)
Stroke 9 - Little Black Backpack (heard)
Longwave - Secrets Are Sinister (heard)
Never Heard:
Bojobian - Still There (never heard)
Dear and the Headlights - Talk About (never heard)
The Slip - Eisenhower (never heard)
DNA's Evolution - The Heist (never heard)
Blackmarket - Tongue Twister Typo (never heard)
Furly - Icarus' Song (never heard)
12 songs, 6 from bands I've heard before, 6 bands I've never heard of.
All good songs, but at the same time, I feel like if some of these songs had been released as normal DLC, like as a single alongside a bigger band pack, I wouldn't have purchased them.
I feel like I really want to support some of these smaller bands, especially with their investment into RBN. I could just imagine how I would feel if I had a song by my band in RBN and it started to sell some songs.
Probably also due to the excitement of it being RBN launch day, I want to buy a bunch of stuff.
Anyone feel the same?


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La Serna High School is four quarters away from its ultimate goal.
A CIF-SS Southeast Division crown is at stake as the Lancers (12-1) face Downey (10-3) in today's championship game at Cal State Fullerton at 7 p.m.
A victory would give La Serna its first CIF-SS football title since 1967. If Downey wins, it would be the Vikings' first CIF football crown since 1957.
Today's game marks the second meeting of the season between the teams. On Aug. 31, La Serna defeated Downey 28-27 in week one. It was the regular season's second game for both schools.
Things have changed considerably since that meeting, according to La Serna coach Margarito Beltran.
"That was a long time ago," Beltran said. "They've gotten better and we've gotten better. There's a sense of similarity because we played against them earlier in the year.
"It's going to come down to matchups and how our kids play. Downey has some kids who are explosive. They play good football."
One of those explosive players for the Vikings is sophomore Justin Huff, who has rushed for 2,140 yards and 22 touchdowns. Huff, who ran for 238 yards and three scores in last week's 35-3 semifinal win over Santa Fe, is averaging 9.8 yards per carry.
Downey coach Jack Williams is thrilled with his team's championship opportunity.
"We're honored to be in the game," he said. "It's an honor to play La Serna. It's going to be tough. The La Serna defense is solid and they're led by quarterback Frankie Palmer, who gets the job done.
"They're coached really well and we have our work cut out for us."
Williams thought this season would be a year of transition for the Vikings.
"We lost a lot of guys from last year," he said. "We thought that this year was going to be a rebuilding year. The team's hard work is a reason why we're here."
The Lancers clinched their final-round berth by beating two-time defending champion West Covina 35-17 in last week's semifinal.
Palmer leads a La Serna offense that averaged 204.7 rushing and 153.1 passing yards heading into the Lancers' semifinal triumph over the Bulldogs. He has thrown for 1,925 yards and 19 touchdowns while completing 60.6 percent of his passes.
Luke Gonzales paces the Lancers' ground game with 808 yards and 11 scores. He had a 50-yard scoring run in last week's victory over West Covina.
Defensive lineman Isaiah Osorio and linebackers Luis Camacho, John McFarland and Michael Dingillo lead a stellar La Serna defense that has produced 41 sacks.
Osorio has 13 sacks while Camacho and McFarland have 12 and 7, respectively. Dingillo has a team-high 98 tackles.
Downey quarterback Jorge Reyna also plays a key role for the Vikings. He has rushed for 926 yards and five touchdowns. Reyna has also passed for 1,295 yards and 11 scores.


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Two top Senate Democrats released competing plans for how to respond to the Snowden disclosures about sweeping NSA surveillance: one regulates the program, the other ends it.
By Gail Russell Chaddock, Staff writer / November 1, 2013
Congress is poised to take steps to rein in the National Security Agency, amid serial leaks about the agency's surveillance activities that seemed to take lawmakers and sometimes even President Obama by surprise. What's not clear is just how sharply it will yank the NSA's chain.


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My Hyperhidrosis Treatment with Dr. Sharon Giese
July 2, 2010
I have gotten so many questions and comments about my underarm sweating/ veal chop procedure (lol) that I realized I need to share the experience with everyone.
I have had this condition of excess perspiration since I was 21 years old.
It was so embarrassing to see huge round sweat marks and worse was how it ruined all my silk dresses /tops and wool and cashmere sweaters. They would stain and never come out!!!
Now for the more technical terms. This condition is formally known as "Hyperhidrosis". According to google health, Hyperhidrosis "is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest".
When Dr. Giese, whom I trust implicitly, first suggested I try her Hyperhidrosis Treatment with internal ultra sound under local anesthesia (she is only one of a few that do it} I admit I was nervous.
How much would it hurt? Where would the sweat go, would it be unhealthy? What would the recovery be like?
I decided to first try a prescription deodorant called drysol. Well you can only use drysol at night, then you have to wear a T-shirt. I tried it for a while but I would forget some nights and I don't like sleeping in a t-shirt!!
So back to Dr. Giese I went.
I asked her will I sweat more somewhere else if I stop sweating under my arm?, is it unhealthy to kill these sweat glands? She assured me there would be no negative consequences and she was right there has been none!
She told me I would have no pain, as I am a nervous nelly when it comes to pain and guess what there was NO PAIN during the procedure.
She told me there would be discomfort after and prescribed pain killers.
But guess what…I did NOT NEED THEM, I only took 3 advils and I had just done the procedure when i was filming at the Four Seasons for lunch with Jill and Sonya asking them to come to St John for the RHONYC.
The only drawback for me was that i could not work out my arms for 3 weeks, but it was well worth it.
I no longer have sweaty underarms, I no longer have huge wet marks. Do you know how embarrassed I was every time I would film…certain clothes would sweat up and now that is no more, it's all gone.
Botox would have been the only other option and that averages $1500 – $2500 per session every 8 – 10 months! This procedure costs $4500, took only 30 MINUTES and provided PERMANENT results!!
I am SO HAPPY with the results. I highly recommend this procedure to anyone and everyone!
Avoid painful injections and save money by visiting Dr Sharon Giese. In fact, if you make an appointment with her office in the month of July and mention my name you'll get a discount!
She is the best in whatever she does, she is a perfectionist!!
To learn more about Dr. Giese:
Visit: http://www.drsharongiese.com/
Or call: (212) 421-3400
Hope this helps!,
Ramona xo
Credit: Google Health


text:
Full-size standard orders $25+ ship free. Order by 2 p.m. ET 12/19 for 12/24 delivery.*
I love that this is all natural and it works instantly! It's also easy to travel with because it is compact. It worked immediately. I just had to dampen the material and it removed stains right away!
I personally love the smell of soap, and I mean the smell of freshly scrubbed laundry kind of soap. The bar is much smaller than I thought it would be - it's only about the size of a hotel bar of soap - but it's supposed to be portable. I love it!
It took a stubborn grease stain off of a gentle fabric. I am so very happy because the item was new!
Very easy to use and effective pre-treat for stains especially red wine. I have yet to see it actually remove stains without washing after use but I am ok with that. The scent is no unpleasant but it is so STRONG. I eventually had to put it in a ziplock bag to not constantly smell it. The paper packaging also leaves a little to be desired due to the scent and the fact that the bar often gets wet when you use it. Would be much better in a travel case. I dont believe this could just be thrown back in your purse "as is" right after use. Not a bad product but not convinced that a stain removal "stick" from the grocery store isnt more convinient.
I'm a bit busty and inevitably my bust occasionally catches spills and drips. I was dissappointed when a favorite silk shirt got a bit on it one day and I used this and it was gentle and just right to use on my dry clean only shirt =)
I travel often as does my husband. We both swear by this. Perfect for when the waiter spills something on you ,ot you packed limited items and your stay was extended. Have yet to find something it cant get out. Highly reccomend.
Yep, you read correctly. I carry a bar of soap with me in my purse. Never have before, but now I do :) My work office building bathroom's have the worst soap and thanks to this sample, I have found a solution. This will certainly be my next purchase.
Works great, but unless I am going on a trip and need something to cleanse my clothes at the hotel, I just can't see buying this as I use borax at home.
I could not be more pleased with how this works. I had gotten a small stain on a merino wool sweater and used the stain bar before washing the sweater in the Laundress Wool & Cashmere Shampoo. The stain is completely gone. I will definitely keep buying this bar. I hope you'll start carrying the Wool & Cashmere Shampoo here soon as well, as it's also a marvelous product.
Jury's still somewhat out on this one, as the stains it's been tasked with removing were tough cases, but in terms of efficacy, it seem so "gentle" that it might not be doing a bang-up job. Still, I'd pick this any day over stringent chemicals, and its size is so convenient for packing, storing, etc. Overall: positive!


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President Obama: Out of control spending?? Not hardly
Wednesday, May 23rd, 2012Self appointed savior of free enterprise Mitt Romney recently attacked President Obama for "out of control spending", claiming he would lead us out of "spending inferno". It took MarketWatch, a division of that liberal bastion The Wall Street Journal (owned by Fox News parent News Corp) to dispel that big fat lie.
Almost everyone believes that Obama has presided over a massive increase in federal spending, an "inferno" of spending that threatens our jobs, our businesses and our children's future. But it didn't happen. Although there was a big stimulus bill under Obama, federal spending is rising at the slowest pace since Dwight Eisenhower brought the Korean War to an end in the 1950s. Even hapless Herbert Hoover managed to increase spending more than Obama has.
Bolded emphasis is mine. Mitt Romney apparently subscribes to the Karl Rove tactic of "If you tell a lie big enough and keep repeating it, people will eventually come to believe it" (Even though Karl Rove stole that idea from a guy named Joseph Goebbels). I subscribe more to the "a picture is worth a thousand words" line of thought:
Big spender? That "severely conservative" Ronald Reagan leads the list. Bush the Wiser gave it his old college try and far outspent Bill Clinton, but was far outdone by Bush the Lesser. But President Obama? A clear lightweight when it comes to growth of federal spending. In the 2009 fiscal year — the last of George W. Bush's presidency — federal spending rose by 17.9% from $2.98 trillion to $3.52 trillion. In fiscal 2010 — the first budget under Obama — spending fell 1.8% to $3.46 trillion. Over Obama's four budget years, federal spending is on track to rise from $3.52 trillion to $3.58 trillion, an annualized increase of just 0.4%. Numbers don't lie, unfortunately politicians do often. Republicans also love claiming that the national debt is "exploding" under President Obama. It is true that the national debt has risen from $10.6 trillion to $15.6 trillion under Obama's watch, which makes for easy partisan attacks. But the vast bulk of the increase was caused by a combination of revenue losses due to the 2008-09 economic downturn as well as Bush-era tax cuts and automatic increases in safety-net spending that were already written into law. Make no mistake, current deficits and increases to the national debt are unsustainable. When we have fully recovered from the worst recession since the Great Depression we must address deficit spending and pay down our debt. Like Bill Clinton did, like GW Bush should have.
Another saying I like is "people who live in glass houses shouldn't throw stones". Mitt Romney should know a thing or two about "out of control spending". During his four years as governor of Massachusetts, state spending increased by 6.5% per year, government jobs grew six times as fast as private sector jobs, taxes and fees went up by $750 million each year, and debt increased by 16%. In fact, he left Massachusetts with the largest per-capita debt of any state in the country.
Mitt Romney says he want the economy to be the focus of his campaign. We say "bring it on".


text:
- Kelly Slutz '14
- Hometown: Smithville, Ohio
- Major: Spanish and Sociology
When I was in high school, I knew I wanted to attend a college that had strong academics, recreational opportunities and lots of different ways to get involved. I also wanted to attend a university that was committed to the environment and the community, and I felt like all of these things were important at Mount Union.
Human Development and Family Science Major and Minor Requirements
Required Core Courses
- Introduction to Psychological Science
- Introduction to Sociology
- Lifespan Development
- The American Family
Complete a two course series in research and statistical methods from the following
- Research Methods and Data Analysis I
- Research Methods and Data Analysis II or
- Social Science Research Methods
- Social Science Statistics and Analysis
Students SCE course(s) will be determined by the research and statistical methods track chosen above. Students will consult with their advisor to determine which choice is appropriate.
- Senior Projects 1
- Senior Projects 2 or
- Senior Practicum
Core Distribution Courses
- Human Development
- Juvenile Delinquency
- Child and Adolescent Development
- Adulthood and Aging
- Abnormal Psychology
- Child and Adolescent Psychopathology
- Psychology of Gender
Family Development
- Family Violence
- Stress and Wellbeing
- Courtship and Marriage
- Social Gerontology
- Drugs and Behavior
- Introduction to Marriage and Family Therapy
Society and Culture
- Contemporary Social Issues
- Educational Psychology
- The Many Faces of Poverty
- Sociology of Gender
- Social Psychology
- Drugs and Society
- Deviance


text:
Defense Acquisitions:
Improved Management and Oversight Needed to Better Control DOD's Acquisition of Services
GAO-07-832T, May 10, 2007
Additional Materials:
- Highlights Page:
- Accessible Text:
The Department of Defense (DOD) is relying more and more on contractors to provide billions of dollars in services. Congress has pushed DOD to employ sound business practices when using the private sector for services. This testimony discusses DOD's (1) increasing reliance on contractors; (2) efforts to follow sound business practices when acquiring services; and (3) actions to improve its management and oversight of services. This testimony is based on GAO's work spanning several years as well as recent reports issued by the Inspectors General.
Over the past decade, DOD has increasingly relied on contractors to provide a range of mission-critical services from operating information technology systems to providing logistical support on the battlefield. The growth in spending on services clearly illustrates this point. DOD's obligations on service contracts, expressed in constant fiscal year 2006 dollars, rose from $85.1 billion in fiscal year 1996 to more than $151 billion in fiscal year 2006, a 78 percent increase. While obligations increased, the size of the civilian workforce decreased. Moreover, DOD carried out this downsizing without ensuring that it had the requisite skills and competencies needed to manage and oversee service acquisitions. Overall, our work found that to a large degree, this growth in spending on services simply happened and was not a managed outcome. The lack of sound business practices--poorly defined requirements, inadequate competition, the lack of comprehensive guidance and visibility on contractors supporting deployed forces, inadequate monitoring of contractor performance, and inappropriate use of other agencies' contracts and contracting services--expose DOD to unnecessary risk, waste resources, and complicate efforts to hold contractors accountable for poor service acquisition outcomes. For example, DOD awarded contracts for security guard services supporting 57 domestic bases, 46 of which were done on an authorized, sole-source basis. The sole-source contracts were awarded by DOD despite recognizing it was paying about 25 percent more than previously paid for contracts awarded competitively. Further, the lack of sufficient surveillance on service contracts placed DOD at risk of being unable to identify and correct poor contractor performance in a timely manner and potentially paying too much for the services it receives. Overall, DOD's management structure and processes overseeing service acquisitions lacked key elements at the strategic and transactional levels. DOD has taken some steps to improve its management of services acquisition, including developing a competency model for its contracting workforce; issuing policies and guidance to improve its management of contractors supporting deployed forces and its use of interagency contracts; and developing an integrated assessment of how best to acquire services. DOD leadership will be critical for translating this assessment into policy and, most importantly, effective frontline practices. At this point, DOD does not know how well its services acquisition processes are working, which part of its mission can best be met through buying services, and whether it is obtaining the services it needs while protecting DOD's and the taxpayer's interests.
Dec 11, 2013
Modernizing the Nuclear Security Enterprise
Defense Management
Nov 20, 2013
Civil Support
Nov 19, 2013
Navy Shipbuilding
Nov 13, 2013
Defense Logistics
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Defense Health Care Reform
Oct 30, 2013
Military Airlift
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Paul's Counter-Cultural Message to Women (and Men)
1 Timothy 2:11-15 is a passage of Scripture that has been picked up by all sorts of folks, abused, misused, and mishandled. It's justified all sorts of bad theology complete with lives that reflect Jesus poorly because of said theology.
Last Sunday, I preached on the issue showing that Paul's words to women have been controversial (for different reasons) from the time he wrote them up to today. Give it a listen if you have a chance and weigh in with what you think about the Women teaching & holding authority.
Tomorrow: Some more thoughts on education.


text: This weekend was pretty cool. Friday night was spent with my favorite professor from college and some colleagues at his beautiful home on the North side of Chicago. We had a chance to reminisce about the good ole days and inform each other about what we're doing today. Everyone agreed that we should get together more often. It felt good to be ... Read More »


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Hox gene
Hox genes (from an abbreviation of homeobox) are a group of related genes that control the body plan of the embryo along the anterior-posterior (head-tail) axis. After the embryonic segments have formed, the Hox proteins determine the type of segment structures (e.g. legs, antennae, and wings in fruit flies or the different vertebrate ribs in humans) that will form on a given segment. Hox proteins thus confer segmental identity, but do not form the actual segments themselves [1]
Hox genes are defined as having the following properties:
- their protein product is a transcription factor
- they contain a DNA sequence known as the homeobox
- in many animals, the organization of the Hox genes on the chromosome is the same as the order of their expression along the anterior-posterior axis of the developing animal, and are thus said to display colinearity.[2]
- 1 Hox proteins
- 2 Sequence and functional conservation
- 3 Classification of Hox proteins
- 4 Genes regulated by Hox proteins
- 5 Enhancer sequences that are bound by homeodomains
- 6 Regulation of Hox genes
- 7 Colinearity of Hox genes
- 8 Hox nomenclature
- 9 Human genes
- 10 History
- 11 See also
- 12 References
- 13 Further reading
- 14 External links
Hox proteins[edit]
The products of Hox genes are Hox proteins. Hox proteins are transcription factors, which are proteins that are capable of binding to specific nucleotide sequences on the DNA called enhancers where they either activate or repress genes. The same Hox protein can act as a repressor at one gene and an activator at another. For example, in flies (Drosophila melanogaster) the protein product of the Hox gene Antennapedia activates genes that specify the structures of the 2nd thoracic segment, which contains a leg and a wing, and represses genes involved in eye and antenna formation.[3] Thus, legs and wings, but not eyes and antennae, will form wherever the Antennapedia protein is located. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60 amino acid long DNA-binding domain (encoded by its corresponding 180bp DNA sequence, the homeobox). This amino acid sequence folds into a helix-turn-helix motif that is stabilized by a third helix. The consensus polypeptide chain is (typical intron position noted with dashes):[4]
Sequence and functional conservation[edit]
The homeodomain protein motif is highly conserved across vast evolutionary distances. In addition, homeodomains of individual Hox proteins usually exhibit greater similarity to homeodomains in other species than to proteins encoded by adjacent genes within their own Hox cluster. These two observations led to the suggestions that Hox gene clusters evolved from a single Hox gene via tandem duplication and subsequent divergence and that a prototypic Hox gene cluster containing at least seven different Hox genes was present in the common ancestor of all bilaterian animals.[5]
The functional conservation of Hox proteins can be demonstrated by the fact that a fly can function perfectly well with a chicken Hox protein in place of its own.[6] This means that, despite having a last common ancestor that lived over 670 million years ago,[7] a given Hox protein in chickens and the homologous gene in flies are so similar that they can actually take each other's places.
Classification of Hox proteins[edit]
Proteins with high degree of sequence similarity are also generally assumed to exhibit a high degree of functional similarity, i.e. Hox proteins with identical homeodomains are assumed to have identical DNA-binding properties (unless additional sequences are known to influence that). To identify the set of proteins between two different species that are most likely to be most similar in function, classification schemes are used. For Hox proteins, three different classification schemes exist: phylogenetic inference based, synteny based, and sequence similarity based.[8]
Genes regulated by Hox proteins[edit]
Hox genes act at many levels within developmental gene hierarchies: at the "executive" level they regulate genes that in turn regulate large networks of other genes (like the gene pathway that forms an appendage). They also directly regulate what are called realisator genes or effector genes that act at the bottom of such hierarchies to ultimately form the tissues, structures, and organs of each segment. Segmentation involves such processes as morphogenesis (differentiation of precursor cells into their terminal specialized cells), the tight association of groups of cells with similar fates, the sculpting of structures and segment boundaries via programmed cell death, and the movement of cells from where they are first born to where they will ultimately function, so it is not surprising that the target genes of Hox genes promote cell division, cell adhesion, apoptosis, and cell migration.[9]
Organism | Target gene | Normal function of target gene | Regulated by |
Drosophila | distal-less | activates gene pathway for limb formation | ULTRABITHORAX[10]
(represses distal-less) |
distal-less | activates gene pathway for limb formation | ABDOMINAL-A[10]
(represses distal-less) |
decapentaplegic | triggers cell shape changes in the gut that are
required for normal visceral morphology |
(activates decapentaplegic) |
reaper | Apoptosis: localized cell death creates the segmental
boundary between the maxilla and mandible of the head |
(activates reaper) |
decapentaplegic | prevents the above cell changes in more posterior
positions |
(represses decapentaplegic) |
Mouse | EphA7 | Cell adhesion: causes tight association of cells in
distal limb that will form digit, carpal and tarsal bones |
(activates EphA7) |
Cdkn1a | Cell cycle: differentiation of myelomonocyte cells into
monocytes (white blood cells), with cell cycle arrest |
(activates Cdkn1a) |
Enhancer sequences that are bound by homeodomains[edit]
The DNA sequence that is bound by the homeodomain protein contains the nucleotide sequence TAAT, with the 5' terminal T being the most important for binding.[14] This sequence is conserved in nearly all sites recognized by homeodomains, and probably distinguishes such locations as DNA binding sites. The base pairs following this initial sequence are used to distinguish between homeodomain proteins, all of which have similar recognition sites. For instance, the nucleotide following the TAAT sequence is recognized by the amino acid at position 9 of the homeodomain protein. In the maternal protein Bicoid, this position is occupied by lysine, which recognizes and binds to the nucleotide guanine. In Antennapedia, this position is occupied by glutamine, which recognizes and binds to adenine. If the lysine in Bicoid is replaced by glutamine, the resulting protein will recognize Antennapedia-binding enhancer sites.[15]
However, all homeodomain-containing transcription factors bind essentially the same DNA sequence. The sequence bound by the homeodomain of a Hox protein is only 6 nucleotides long, and such a short sequence would be found at random many times throughout the genome, far more than the number of actual functional sites. Especially for Hox proteins, which produce such dramatic changes in morphology when misexpressed, this raises the question of how each transcription factor can produce such specific and different outcomes if they all bind the same sequence. One mechanism that introduces greater DNA sequence specificity to Hox proteins is to bind protein cofactors. Two such Hox cofactors are Extradenticle (Exd) and Homothorax (Hth). Exd and Hth bind to Hox proteins and appear to induce conformational changes in the Hox protein that increase its specificity [16]
Regulation of Hox genes[edit]
Just as Hox genes regulate realisator genes, they are in turn regulated themselves by gap genes and pair-rule genes, which are in their turn regulated by maternally-supplied mRNA. This results in a transcription factor cascade: maternal factors activate gap or pair-rule genes; gap and pair-rule genes activate Hox genes; then, finally, Hox genes activate realisator genes that cause the segments in the developing embryo to differentiate. Regulation is achieved via protein concentration gradients, called morphogenic fields. For example, high concentrations of one maternal protein and low concentrations of others will turn on a specific set of gap or pair-rule genes. In flies, stripe 2 in the embryo is activated by the maternal proteins Bicoid and Hunchback, but repressed by the gap proteins Giant and Kruppel. Thus, stripe 2 will only form wherever there is Bicoid and Hunchback, but not where there is Giant and Kruppel.[17]
MicroRNA strands located in hox clusters have been shown to inhibit more anterior hox genes ("posterior prevalence phenomenon"), possibly to better fine tune its expression pattern.[18]
Non-coding RNA (ncRNA) has been shown to be abundant in Hox clusters. In humans, 231 ncRNA may be present. One of these, HOTAIR, silences in trans (it is transcribed from the HOXC cluster and inhibits late HOXD genes) by binding to Polycomb-group proteins (PRC2).[19]
The chromatin structure is essential for transcription but it also requires the cluster to loop out of the chromosomal territory.[20]
In higher animals including humans, retinoic acid regulates differential expression of Hox genes along the anteroposterior axis.[21] Genes in the 3' ends of Hox clusters are induced by retinoic acid resulting in expression domains that extend more anteriorly in the body compared to 5' Hox genes that are not induced by retinoic acid resulting in expression domains that remain more posterior.
Quantitative PCR has shown several trends regarding colinearity: the system is in equilibrium and the total number of transcripts depends on the number of genes present according to a linear relationship.[22]
Colinearity of Hox genes[edit]
In some organisms, especially vertebrates, the various Hox genes are situated very close to one another on the chromosome in groups or clusters. Interestingly, the order of the genes on the chromosome is the same as the expression of the genes in the developing embryo, with the first gene being expressed in the anterior end of the devesm. The reason for this colinearity is not yet completely understood. The diagram above shows the relationship between the genes and protein expression in flies.
Hox nomenclature[edit]
Hox genes in different phyla have been given different names, which has led to confusion about nomenclature. The complement of Hox genes in Drosophila is made up of two clusters, the Antennapedia complex and the Bithorax complex, which together are referred to as the HOM-C (for Homeotic Complex). Hox genes (for Homeotic transcription factors[citation needed]) in higher vertebrates are generally arranged in four clusters: Hoxa, Hoxb, Hoxc, and Hoxd. Although historically HOM-C genes have referred to Drosophila homologues, while Hox genes referred to vertebrate homologues, this distinction is no longer made, and both HOM-C and Hox genes are called Hox genes.
Human genes[edit]
Humans have Hox genes in four clusters:
cluster | chromosome | genes |
HOXA | chromosome 7 | HOXA1, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 |
HOXB | chromosome 17 | HOXB1, HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, HOXB13 |
HOXC | chromosome 12 | HOXC4, HOXC5, HOXC6, HOXC8, HOXC9, HOXC10, HOXC11, HOXC12, HOXC13 |
HOXD | chromosome 2 | HOXD1, HOXD3, HOXD4, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, HOXD13 |
Christiane Nüsslein-Volhard and Eric F. Wieschaus identified and classified 15 genes of key importance in determining the body plan and the formation of body segments of the fruit fly Drosophila melanogaster.[when?][citation needed]
In the late 1940s, Edward B. Lewis studied[citation needed] the Hox genes, which specify the identity of each segment after they are formed. Incorrect expression of Hox genes can lead to major changes in the morphology of the individual, called homeotic transformations, where one segment develops into the likeness of another. A famous example in Drosophila melanogaster is the mutation of the Ultrabithorax Hox gene, which specifies the 3rd thoracic segment. Normally, this segment displays a pair of legs and a pair of halteres (a reduced pair of wings used for balancing). In the mutant lacking functional Ultrabithorax protein, the 3rd thoracic segment now expresses the same structures found on the segment to its immediate anterior, the 2nd thoracic segment, which contains a pair of legs and a pair of (fully developed) wings. These mutants sometimes occur in wild populations of flies, and it was these mutants that led to the discovery of Hox genes.
For their work, Nüsslein-Volhard, Wieschaus, and Lewis were awarded the Nobel Prize in Physiology or Medicine in 1995.
In 1983, the homeobox was discovered independently by researchers in two labs: Ernst Hafen, Michael Levine, and William McGinnis (in Walter Gehring's lab at the University of Basel, Switzerland) and Matthew P. Scott and Amy Weiner (in Thomas Kaufman's lab at Indiana University in Bloomington).
See also[edit]
- Homeobox
- Homeotic gene, e.g. Hox
- Morphogenesis
- Discredited hypotheses for the Cambrian explosion (Section: Regulatory genes)
- ^ Joseph C. Pearson, Derek Lemons & William McGinnis "Modulating Hox gene functions during animal body patterning" Nature Reviews Genetics 6, 893-904 (December 2005) doi:10.1038/nrg1726
- ^ Carroll S. B. (1995). "Homeotic genes and the evolution of arthropods and chordates". Nature 376 (6540): 479–85. doi:10.1038/376479a0. PMID 7637779.
- ^ Cesares and Mann 1998; Plaza et al. 2001
- ^ http://www.csb.ki.se/groups/tbu/homeo/consensus.gif
- ^ McGinnis W.; R. Krumlauf (1992). "Homeobox genes and axial patterning". Cell 68 (2): 283–302. doi:10.1016/0092-8674(92)90471-N. PMID 1346368.
- ^ Lutz, B.; H.C. Lu, G. Eichele, D. Miller, and T.C. Kaufman (1996). "Rescue of Drosophila labial null mutant by the chicken ortholog Hoxb-1 demonstrates that the function of Hox genes is phylogenetically conserved". Genes & Development 10 (2): 176–184. doi:10.1101/gad.10.2.176. PMID 8566751.
- ^ Ayala, F.J.; A. Rzhetskydagger (20 January 1998). "Origin of the metazoan phyla: Molecular clocks confirm paleontological estimates". Proc. Natl. Acad. Sci. USA 95 (2): 606–11. doi:10.1073/pnas.95.2.606. PMC 18467. PMID 9435239.
- ^ Hueber S.D.; Weiller G.F., Djordjevic, M. A, Frickey, T. (2010). "Improving Hox Protein Classification across the Major Model Organisms". PLoS ONE 5 (5): e10820. doi:10.1371/journal.pone.0010820. PMC 2876039. PMID 20520839.
- ^ a b Pearson, JC, Lemons, D. and McGinnis, W. Modulating Hox gene functions during animal body patterning. Nature Rev. Genet. 6, 893–904 (2005).
- ^ a b Vachon, G. et al. Homeotic genes of the bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71, 437–450 (1992).
- ^ a b Capovilla, M. & Botas, J. Functional dominance among Hox genes: repression dominates activation in the regulation of dpp. Development 125, 4949–4957 (1998).
- ^ Lohmann, I., McGinnis, N., Bodmer, M. & McGinnis, W. The Drosophila Hox gene Deformed sculpts head morphology via direct regulation of the apoptosis activator reaper. Cell 110, 457–466 (2002).
- ^ Bromleigh, V. C. & Freedman, L. P. p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes Dev. 14, 2581–2586 (2000).
- ^ Gilbert, Developmental Biology, 2006
- ^ Hanes and Brent 1989, 1991
- ^ Richard S. Mann, Katherine M. Lelli, Rohit Joshi. Chapter 3 Hox Specificity: Unique Roles for Cofactors and Collaborators. Current Topics in Developmental Biology, Volume 88, 2009, Pages 63–101 http://dx.doi.org/10.1016/S0070-2153(09)88003-4
- ^ Small S, Blair A, Levine M. 1992. Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J. 1992 Nov;11(11):4047-57
- ^ Lempradl A, Ringrose L. 2008 How does noncoding transcription regulate Hox genes? Bioessays. 30(2):110-21.
- ^ Rinn, JL; Kertesz, M; Wang, JK; Squazzo, SL; Xu, X; Brugmann, SA; Goodnough, LH; Helms, JA et al. (2007). "Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Non-Coding RNAs". Cell 129 (7): 1311–23. doi:10.1016/j.cell.2007.05.022. PMC 2084369. PMID 17604720.
- ^ Fraser, P; Bickmore, W. (2007). "Nuclear organization of the genome and the potential for gene regulation". Nature 447 (7143): 413–7. doi:10.1038/nature05916. PMID 17522674.
- ^ Duester, G (September 2008). "Retinoic Acid Synthesis and Signaling during Early Organogenesis". Cell 134 (6): 921–31. doi:10.1016/j.cell.2008.09.002. PMC 2632951. PMID 18805086.
- ^ Montavon; Le Garrec, JF; Kerszberg, M; Duboule, D (2008). "Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness". Genes Dev. 22 (3): 346–59. doi:10.1101/gad.1631708. PMC 2216694. PMID 18245448.
Further reading[edit]
- Hunt, Paul (1998). "The Function of Hox Genes". In Bittar, E. Edward. Developmental biology. Elsevier. ISBN 978-1-55938-816-0.
External links[edit]
- The Homeotic Selector Genes in Developmental Biology, 6th Edition by Scott F. Gilbert (2000) Published by Sinauer Associates, Inc. ISBN 0-87893-243-7.


text:
Would you guys reccommend doing a cycle of 1test 4ad transdermal if you have a bunch of touchy girlfriends?
If so, how would you go about doing this? I know you could do feet and legs, places where they dont usually touch but what about rotating sites? Arent you suppose to rotate so the skin doesnt get irratated? Last thing i want is my girlfriend to start growing facial hair.
mods: I know i posted this in the Steroid forum also but I just think not too many people check this forum.