text:
Nelson Imperial IPA - Widmer Brothers Brewing Company
Displayed for educational use only; do not reuse. |
Ratings & Reviews |
Sort by: Latest | High | Low | Top Reviewers | Alström Bros |
« first ‹ prev | 1-25 | 26-50 | 51-75 | next › last » |
Ratings: 497 | Reviews: 177 | Show All Ratings:
Reviews by Bighuge:BighugeMinnesota 4.47/5 rDev +13.2% look: 4 | smell: 4.5 | taste: 4.5 | feel: 4.5 | overall: 4.5 Hazy, fuzzy peach colored body. Thin off white heads leaves decent amounts of lace down the glass walls. Nice citric hop aroma. White grapefruit, passion fruit, peach and mango....love what this hop brings to the table. Flavor is all Nelson Sauvin. Love this hop. Citric and tropical. Grapefruit pulp. Apricot. Lemon oil. So flavorful. Clean bitterness. This is a great beer. Serving type: bottle 12-03-2011 05:27:02 | More by Bighuge More User Reviews:delta490Virginia 3.93/5 rDev -0.5% look: 4.25 | smell: 4 | taste: 3.75 | feel: 4.25 | overall: 4 A- poured a cloudy orange gold with a big creamy tan head. Slight retention and some lacing S-aroma is strongly robust caramel and citrus hops in the background T-mirrors the aroma. Big malt backbone and more subtle hops than most imperials M- full with a slight resinous slickness O-not a real hop bomb but well crafted and tasty Serving type: bottle 12-18-2013 03:04:39 | More by delta490 anarchiaOregon 4.05/5 rDev +2.5% look: 3.75 | smell: 4.25 | taste: 4.25 | feel: 3.5 | overall: 3.75 Transparent orange/gold beer with a thin head with good retention. Citrus & floral hops in the nose, thick on the tongue, maybe a tad too "syrupy" for my tastes. Sweet but not quite too sweet. Hops don't kick in immediately, they're much more noticeable in the finish. Individual hop flavors stand out, hitting the tongue one after the other: super fruity, almost like jolly ranchers! Intense orange/grapefruit and other citrusy flavors, slightly bitter finish, fairly dry. I think I would like this beer more if it weren't so "big". There is a lot of amazing flavor squeezed out of the hops without any heavy bitterness. Serving type: bottle 12-13-2013 03:56:50 | More by anarchia joeworrallArizona 4.11/5 rDev +4.1% look: 4 | smell: 3.75 | taste: 4.25 | feel: 4 | overall: 4.25 poured from a bottle into a wine glass, comparing it head to head with Green Flash Green Bullet Triple IPA and New Belgium Imperial IPA. I've heard of Widmer Brothers, but didn't think of them as a "craft" beer brewer until today. I read about this IPA and was anxious to try it. It did not disappoint... Lovely dark amber color, and subtle hop aroma and flavor. Subtle... nice, but not overwhelming. You can taste the malted barley with the hop flavor balancing it. this is a beer I will come back to again... not a bargain, but a well crafted IPA that I will look forward to enjoying again Serving type: bottle 09-22-2013 02:59:39 | More by joeworrall |
« first ‹ prev | 1-25 | 26-50 | 51-75 | next › last » |
Nelson Imperial IPA from Widmer Brothers Brewing Company
out of 100
based on 497 user ratings.


text:
Fabulous, high-end, out of the way place, although not inconvenient to get to. HIghly recommend it. We loved our stay here. Beautiful location and facilities. Very peaceful. The food at the onsite restaurant was very, very good, too.
- Also Known As:
- Algodon Wine Estates & Champions Club Hotel
- Algodon Wine Estates And Champions Club
- Algodon Wine Estates & Champions Club Hotel San Rafael
- Algodon Wine Estates & Champions Club San Rafael, Argentina - Province Of Mendoza
- Official Description (provided by the hotel):
- Algodon Wine Estates is a family-friendly luxury vineyard estate nestled in the southern heart of Mendoza, along the Argentina Wine Route. Guests will enjoy guided winery tours & tastings, internationally award-winning accommodations, the finest traditional Argentine cuisine, championship tennis facilities and a championship golf course that literally plays through vineyards. Appealing to wine and sports lovers alike, the estate also features access to exciting local excursions including rafting, skiing, horseback riding, and much more! ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Expedia, Tablet Hotels, Splendia, Travelocity, Priceline, Hotels.com and Tingo so you can book your Algodon Wine Estates & Champions Club reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.

subset: commoncrawl


text:
FMD is an abbreviation for:
foot and mouth disease
Find a translation for FMD in other languages:
Select another language:
Use the citation below to add this abbreviation to your bibliography:
"FMD." Abbreviations.com. STANDS4 LLC, 2013. Web. 11 Dec. 2013. <http://www.abbreviations.com/term/575407>.
FMD also stands for:
- Face Mounted Display
- Family medical doctor
- Fashion Music And Dance
- Federal Mogul Dragster
- FibroMuscular Dysplasia
... and 8 more »
Nearby & related abbreviations:
Alternative search:
- Search foot and mouth disease on Amazon.com
- Search foot and mouth disease on Google


text:
Trigonometric identities
Proof: cos(a + b) = (cos a)(cos b) - (sin a)(sin b) Proof of the trig identity: cos(a+b) = (cos a)(cos b)-(sin a)(sin b)
⇐ Use this menu to view and help create subtitles for this video in many different languages.
You'll probably want to hide YouTube's captions if using these subtitles.
- Welcome back.
- We'll now try to see what trigonometric identity we can
- come up with if we start off with cosine of alpha plus beta.
- Let's see if we can rewrite this as another combination
- of cosines and sines of alpha and beta.
- So let's get started.
- And if you've already watched the sine equivalent of this,
- this proof will be pretty similar in how we operate.
- And we get a kind of similar answer.
- And something interesting is to kind of compare the difference
- between sine of alpha plus beta and cosine of alpha plus
- beta after we're done.
- So just like that last proof, let's say that this angle-- no,
- that color isn't bright enough.
- Let's do yellow.
- Let's say that this angle right here is alpha, and this
- angle right here is beta.
- Right?
- We want to know cosine of alpha plus beta.
- So alpha plus beta is this large angle right here.
- Right?
- So what's the cosine of that?
- So cosine is adjacent over hypotenuse.
- Right?
- So cosine is equal to adjacent over hypotenuse.
- So for this large angle, what's the adjacent?
- It's line AC.
- So that equals-- line AC, that's the adjacent.
- The length of line AC over the length of line--
- what's the hypotenuse?
- AB, right?
- All right.
- AC over AB.
- Now let's see what we can do with this.
- AC-- adjacent over hypotenuse.
- Now can we write AC in any other interesting way-- a
- combination of some of the other lines on this very
- fortunately designed graph?
- Let's see.
- Well isn't AC the same thing as AF, this big line,
- minus-- what is this?
- This is a D, right?
- That's a D.
- Let me rewrite that as a D.
- D as in dog.
- There you go.
- So AF minus DE.
- Right?
- Oh, I forgot to draw some things.
- We assume that this line is perpendicular to that line.
- We assume this line is perpendicular to that line.
- We assume that line is perpendicular to that line.
- Right?
- And then by definition, that is because we drew it that way.
- But anyway.
- So now you know that this line is parallel to this line and
- this line is perpendicular.
- So we know that AF, this long line, minus DE is equal to AC.
- Does that make sense?
- AF, this big line, minus the shorter line is
- the same thing as AC.
- Right?
- So let me write that down.
- That equals AF minus DE, all of that over AB.
- And then, of course, we can rewrite that as-- and I'm going
- to switch to some different colors-- as AF over AB.
- Let me switch to maybe green.
- Minus DE over AB.
- So we have now AF over AB minus DE over AB.
- And those are kind of nonsensical ratios to me.
- Wouldn't it be great if we could express it
- somehow as AF over AE?
- Because then we could say well that's cosine of alpha, and
- do something from there.
- Well let's try.
- So let's try to rewrite this first expression.
- So I'll switch back to the purple just so you
- know where this first expression is coming from.
- Let's see if we can break this down as AF over AE
- times something else.
- Well, we could just algebraically do it.
- That's equivalent to AF over-- I might run out of space--
- over AE times AE over AB.
- And you're saying, Sal where did you get that from?
- Well, you can kind of say my motivation was to have AF
- as a ratio of over AE.
- And I just set it up so that the multiplication would cancel
- out, because the AE's would cancel out and you'd be
- left with AF over AB.
- Right?
- So this is a reasonable thing to do.
- I hope you see.
- And let me switch to the green and do something similar.
- DE over AB doesn't make much sense.
- But if I could maybe do DE over BE, then if this angle I can
- see is similar to alpha or beta then maybe I can
- make some progress.
- So let's say DE over BE times-- and we'll do the same thing.
- You just have to multiply times BE over AB.
- And just like in that sine proof, and we'll do the same
- thing here, let's figure out what this angle up here is.
- Right?
- Because if we know that then these ratios become useful.
- So if this angle is an alpha, then we know that this
- angle right here is alpha.
- Right?
- Because DE-- because this line-- is parallel to AF.
- You learned that in geometry.
- And if this angle is alpha we know that this angle right here
- is 90 minus alpha, because it's complementary.
- Right?
- Because this whole angle is 90 degrees, so this
- is 90 minus alpha.
- And since this angle 90 minus alpha, this angle 90, and this
- angle add up to 180, we could figure out that this is alpha.
- And if you don't believe me add up alpha plus 90 plus 90 minus
- alpha, and you will get 180 degrees.
- So this angle up here, angle DBE, is alpha.
- So that's very interesting.
- So can we rewrite these ratios as the sines or cosines
- of alpha's or beta's?
- Well, let's try.
- Let me switch back to purple.
- So that equals-- what is AF over AE?
- Well if we look at this right triangle, that's the adjacent
- over the hypotenuse for alpha.
- Right?
- Adjacent over hypotenuse, that's cosine.
- So it's cosine of alpha.
- And what's AE over AB?
- Well, they're similar.
- If we look at this big right triangle right here that is the
- adjacent over the hypotenuse for beta, so it's
- cosine of beta.
- Switch my colors.
- Minus DE over BE.
- Well this is alpha, right?
- Now there's a little smudge.
- You probably can't read it.
- But that was alpha.
- We showed that that was alpha.
- So DE is the opposite and BE is the hypotenuse.
- Opposite over hypotenuse is sine, right?
- So that's sine of alpha.
- And what is BE over AB?
- Look at this triangle again.
- Well, for beta that is BE is the opposite and
- AB is the hypotenuse.
- So opposite over hypotenuse for beta.
- So it's the sine of beta.
- Times the sine of beta.
- I'm running out of space.
- I have to go to another line.
- Pretty neat.
- I'll rewrite everything in a new and exciting color.
- Let me do it in light blue.
- So we now know that the cosine of alpha plus beta is equal to
- the cosine of both of them multiplied-- so cosine of
- alpha, cosine of beta-- minus the sine of both of
- them multiplied.
- Minus sine of alpha times sine of beta.
- I hope you found that as satisfying as I do.
- See you in the next presentation.
Be specific, and indicate a time in the video:
At 5:31, how is the moon large enough to block the sun? Isn't the sun way larger?
Have something that's not a question about this content? |
This discussion area is not meant for answering homework questions.
Share a tip
When naming a variable, it is okay to use most letters, but some are reserved, like 'e', which represents the value 2.7831...
Thank the author
This is great, I finally understand quadratic functions!
Have something that's not a tip or thanks about this content? |
This discussion area is not meant for answering homework questions.
Report a mistake in the video
At 2:33, Sal said "single bonds" but meant "covalent bonds."
Discuss the site
For general discussions about Khan Academy, visit our Reddit discussion page.
Flag inappropriate posts
Here are posts to avoid making. If you do encounter them, flag them for attention from our Guardians.
- disrespectful or offensive
- an advertisement
not helpful
- low quality
- not about the video topic
- soliciting votes or seeking badges
- a homework question
- a duplicate answer
- repeatedly making the same post
wrong category
- a tip or thanks in Questions
- a question in Tips & Thanks
- an answer that should be its own question
about the site


text:
North Penn survived Souderton 3-2 in boys volleyball on Monday. The Knights won the first two games, 27-25 and 22-21. The Indians then took control winning 25-21 and 25-19. In the pivotal fifth game, NP won 15-13.
Souderton 15, Quakertown 11
Quakertown and Souderton had an offensive battle on Monday. Souderton pulled out the win scoring 15 runs on 11 hits. Sophomore Heather Milligan earned the win on the mound. Three pitchers saw action in the circle for Souderton, but Milligan was the one that was on the mound when Souderton took the lead for good. Offensively for Souderton, Paige Shelly had the first HR of the season going deep over the fence in left center. Nikki Canfield, Sarah Derstine, and Lauren Urbanski all had two doubles. Urbanski led the team with 3 RBIs. Haley DeLany had a double and three walks. Souderton plays a night game vs Pennridge on Wednesday at Drunkenmiller Park.
Souderton 15, Quakertown 11
Souderton 1 7 0 5 2 0 15 12 4
Quakertown 2 0 6 0 0 2 1 11 11 5
WP- Heather Milligan LP- J. Cramp
Paige Shelly: 2 for 4, 1 R, 2 RBI, HR, BB
Meghan Weisel: 2 for 5, 2 R
Sarah Derstine: 2 for 4, 2 R, RBI, 2- 2B, BB
Nikki Canfield: 2 for 3, 2 R, 2 RBI, 2- 2B
Lauren Urbanski: 2 for 3, 2 R, 3 RBI, 2- 2B
Haley DeLany: 1 for 1, 2 R, 2 RBI, 2b, 3 BB
Corrine Stiles: 2 RBI, Erelle Sowers, RBI, Milligan, RBI
Tuesday, April 17
West Chester Christian at Calvary Baptist, 3:45 p.m.
Upper Moreland at Wissahickon, 3:30 p.m.
Conwell-Egan at Lansdale Catholic, 3:45 p.m.
St. Basil at Gwynedd Mercy, 3:45 p.m.
Girls Lacrosse
Nazareth Academy at Gwynedd Mercy, 3:45 p.m.
Boys Track
Souderton at Quakertown, 3:30 p.m.
Pennridge at Hatboro-Horsham, 3:30 p.m.
Central Bucks East at Central Bucks West, 3:30 p.m.
Wissahickon at Upper Moreland, 3:30 p.m.
Central Bucks South at North Penn, 3:45 p.m.
Girls Track
North Penn at Central Bucks South, 3:30 p.m.
Quakertown at Souderton, 3:30 p.m.
Hatboro-Horsham at Pennridge, 3:30 p.m.
Central Bucks West at Central Bucks East, 3:30 p.m.
Upper Moreland at Wissahickon, 3:30 p.m.
Gwynedd mercy at St.Basil, 3:45 p.m.
Boys Volleyball
North Penn at Central Bucks South, 3:30 p.m.
Central Bucks West at Souderton, 7 p.m.
Unionville at Christopher Dock, 7 p.m.
Pennridge at Cheltenham, 7 p.m.
Boys Tennis
Souderton at North Penn, 3:30 p.m.
Central Bucks West at Pennridge, 3:30 p.m.
Holy Ghost Prep at Christopher Dock, 3:45 p.m.


text:
My stay at your hotel is always very pleasurable. The staff is awesome and the rooms are always great. I would suggest some different pillow selections. The location is great close to everything that I need.
- Also Known As:
- Hampton Inn & Suites St Cloud Hotel Saint Cloud
- Hampton Inn And Suites St Cloud
- Hampton Inn & Suites St Cloud Hotel
- Reservation Options:
- TripAdvisor is proud to partner with Expedia, Travelocity, Hotels.com, Booking.com, Priceline, Hilton Hotels, Venere, Otel and Tingo so you can book your Hampton Inn & Suites St Cloud reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.


text:
We're working with you to make a positive impact around the world in more than 35 countries, all 50 United States and your backyard. Support our work
Annual reports and financial reports give us the opportunity to report to you — the people who support us and make our work possible — on our recent achievements. But the work we do far exceeds the capacity of these reports to ell our story. This past year, The Nature Conservancy was involved in hundreds of projects in all 50 United States and more than 30 countries around the world.
The Nature Conservancy meets all of the Better Business Bureau (BBB) Wise Giving Alliance Standards for Charity Accountability.
The American Institute of Philanthropy has awarded The Nature Conservancy an "A-" rating.
The Nature Conservancy's strong performance is recognized with high ratings for accountability and transparency by Charity Navigator.
Forbes magazine rated The Nature Conservancy's fundraising efficiency at 88% in its annual survey of the largest U.S. charities.
Financial information about The Nature Conservancy may be obtained by contacting us at 4245 North Fairfax Drive, Suite 100, Arlington, VA 22203; (800) 628-6860, or as stated in our Charitable Solicitation Disclosure.
Nature springs to life in Nature Conservancy magazine. Read
The most vital habitats on Earth need your support. Make a donation


text:
Our sense of hearing is truly remarkable, all the more so when you understand the rich layers of information that exist within even a single spoken sentence. Of course this is something most of us take for granted, until you discover what life is like for people who don't have the benefit of fully functioning hearing.
I have no direct experience with cochlear implants (CIs) – electronic devices that partly compensate for severe hearing impairment. But listening to a simulation of the sound produced is salutary. It is rather like hearing things underwater: fuzzy and with an odd timbre, yet still conveying words and some other identifiable sounds.
It is a testament to the adaptability of the human brain that this information can be recognizable even when the characteristics of the sound are so profoundly altered. Some people with CIs can appreciate and even perform music.
But there are serious limitations to what people with CIs can hear. And understanding these limitations could provide insights into how sound is processed in people with normal hearing – insights that can help us identify what can potentially go wrong and how it might be fixed. That is evident in a trio of papers buried in the little-known but infallibly fascinating Journal of the Acoustical Society of America – a publication whose scope ranges from urban noise pollution to whale song and the sonic virtues of cathedrals.
Mixed emotions
These three papers examine what gets lost in translation in CIs. Much of the emotional content, as well as some semantic information, in speech is conveyed by the rising and falling of voice – known as prosody. In the English language, prosody can distinguish a question from a statement (at least before the rising inflection became fashionable). It can also tell us whether the speaker is happy, sad or angry.
But CIs cannot fully convey the pitch of sounds, as well as their "spectrum" of sound frequencies, and this means that users may find it harder to tell whether someone's voice is happy rather than sad, for instance. So users rely more on visual than on audio information to gauge a speaker's emotional state.
In the first study, Takayuki Nakata of Future University Hakodate in Japan and his co-workers verified that Japanese children who are born deaf but use CIs are significantly less able to identify happy, sad, and angry voices than normal hearers of the same age. They went further than previous studies, however, by showing that these difficulties prevent children from communicating emotion through prosody in their own speech. This suggests two things: first, that we learn to communicate emotion by hearing and copying; and second, that CI users face an additional burden in that other people are less likely to understand their emotions.
Spotting cues
Difficulties in hearing pitch can create even more severe linguistic problems. In tonal languages such as Mandarin Chinese, changes in pitch may alter the semantic meaning of a word. So CI users may struggle to distinguish such tones even after years of using a device, and hearing-impaired Mandarin-speaking children who start using them before they can speak are often scarcely intelligible to adult listeners – again, they cannot learn to produce the right sounds if they cannot hear them.
To understand how CI users might perceive these language tones, Damien Smith and Denis Burnham of the University of Western Sydney in Australia tested normal hearers with audio clips of spoken Mandarin altered to simulate CIs. The results were surprising.
Both native Mandarin speakers and English-speaking subjects do better in identifying the (four) Mandarin tones when the CI-simulated voices are accompanied by video footage of the speakers' faces. That is not so surprising. But all subjects did better with visuals alone – and in this case non-Mandarin speakers did better than Mandarin speakers.


text: Dr. LobsterDiane Cowan is a scientist who has made lobsters her life's calling. Every month for the past 15 years, she's counted and catalogued juveniles the hard way by hand. She puts up with subzero temperatures, ferocious winds, ruthless insects and feisty lobsters that like to pinch. The result is the most comprehensive data around for juvenile lobsters and the nurseries where they live. |


text:
- Products:
- 1-3 of 3
BenchMens Boxers (3 pack)
Bench Plain Mens Boxers (3 pack)
This three pack of Bench boxers come in no-nonsense, simplistic designs that are ideal for wearing underneath any of your outfits.
Made from cotton fabric that's soft against the skin, they include a tight elasticated waist to keep you comfortable throughout the day. Guaranteed to become a firm favourite, they'll go hand in hand with your everyday lifestyle.
Available in either an all black, black multi or a black/white/grey pack, they all feature 360 degree branding detail across the waistband.
Useful info:
- Mens boxers by Bench
- 3 pack
- Elasticated waist
- 360 degree logo detail
- Available in black, black, white and grey or black multi
- Weekly Price
- From £1.25 per week
- Price
- £25.00
- In Stock
- Availability
- Available
BenchMens Beanie Hat
Bench Beanie Hat
When you're looking for a little bit extra to finish off your laidback styling, Bench bring us a beanie hat that ensures your head is kept warm.
It features a bobble to the crown and is decorated with a multi-coloured pattern to the rim. It's finished off with an embroidered tab attached to the front.
Headwear is bang on trend this season and adds an urban feel to your street outfit. Use this beanie as the final piece when you're wearing a hoodie, jeans and trainers.
Useful info:
- Mens beanie hat by Bench
- Bobble to crown
- Multi-coloured pattern to rim
- Embroidered tab to front
- Weekly Price
- From £1.10 per week
- Price
- £22.00
- In Stock
- Next day delivery available
- Availability
- Available
BenchMens Short Sleeve Shirt
Slim fit short sleeve shirt with chest pocket and logo print detail.
Cotton. Machine washable. Colour: White.- Weekly Price
- From £1.35 per week
- Price
- £27.00
- Low stock, selling fast
- Availability
- Low stock selling fast
- Products:
- 1-3 of 3


text:
BY LIZA STROUT - Gasparilla Island has a bounty of fruits that can be collected simply by stepping into the great outdoors. From guavas and mangos, carissas and sea plums (which are two different species), to Key limes and avocados, a walk through Boca Grande in the summer will show you exactly how productive even a barrier island surrounded by salt water can be.
For many years, the plague of iguanas stripped many of these fruits from the plant before people could collect them, but that has changed.
Late summer is the time of year that Kris Boyden, manager of the Lilly Pulitzer signature store Palm on Park, would usually be collecting and freezing sea grapes –– both on the island and on the mainland –– in preparation for the famous jelly that she sells as a fundraiser for Relay for Life.
Only there is a problem this year. Rather than the large, ripe grapes that she is used to seeing in the late summer, all of the sea grapes, on the island and mainland, are small, green and unripe.
"They just aren't turning," she said. "I don't know what's going on."
It was a sentiment echoed by the Charlotte County Extension Agency Horticulturalist Ralph Mitchell.
"All I can really do is compare it to some of the other fruiting plants in the state," Mitchell said. "We had a few cold snaps this winter, but for the most part it was warmer. I know that peaches had a double bloom, and the fruit is getting ripe a lot later than farmers expected."
Ed Flowers, the forestry resource administrator for the Myakka District, said that the same issue had been seen in a few other plants.
"I know that there have been issues with blueberries in the state," said Flowers. "They bloomed, then there was a cold snap. It was enough to kill the blooms, and they had to start over. So they are ripening late."
Even floridaplants.com mentions that in some years the fruit of the sea grape "may mature in late fall because of late bloom."
So, for those who are waiting to collect the bounty of the sea grape, the consensus seems to be that you just need to give it a little more time.


text:
Forum Rules | Firearms Safety | Firearms Photos | Links | Library | Lost Password | Email Changes |
Register | FAQ | Calendar | Search | Today's Posts | Mark Forums Read |
Thread Tools |
December 24, 2012, 06:07 PM | #1 |
Senior Member
Join Date: March 18, 2009
Location: Central Colorado
Posts: 669
Link to White House petition to ban legislation against "assault weapons"
I'm not sure if this has been posted previously, but it's very close to 25,000 signatures. There's also petitions to remove Piers Morgan and the like.
I don't want this to look like a drive-by, but I've noticed it was difficult to locate these petitions through the search engines.
Always carry an extra magazine when CCW. Friends don't let friends get a double-feed first round out. -Will Last edited by Brian Pfleuger; December 24, 2012 at 06:26 PM. Reason: Remove Link |
December 24, 2012, 06:26 PM | #2 |
Join Date: June 25, 2008
Location: Central, Southern NY, USA
Posts: 16,347
Still happily answering to the call-sign Peetza. --- You do not HAVE a soul. You ARE a soul. You HAVE a body. ----- He is no fool who gives what he can not keep to gain what he can not lose. -Jim Eliott, paraphrasing Philip Henry. |
Thread Tools | |


text:
Staying one step ahead of the intruders
After detecting a rootkit, the only thing that really helps is to completely reinstall the infected system – the malicious software digs far too deep into a system to let you remove it with any degree of certainty. In this light, it makes sense to do everything you can to prevent a rootkit from compromising your system. Prevention is the only real answer – particularly, installing security patches. To prevent malware exploiting them, you need to make sure that you close all known vulnerabilities.
Latest and Greatest
The principle of using the latest software also applies to rootkit scanners. Zeppoo [7] is almost two years old, for example, and fails to detect any of the current crop of rootkits due to total ignorance of their approaches. It is probably best to leave Zeppoo where it is on SourceForge.
The next best obstacle is a firewall, preferably one that controls network traffic in all layers of the TCP/IP stack. For servers in hostile environments, the use of a static kernel and an intrusion detection tool such as OSSEC.
Keep in mind, however, that humans are possibly the biggest attack vector for rootkits. If a user is enticed by phishing mails or enlargement offers, the best security mechanisms are no doubt doomed to failure.
- Blue Pill: http://en.wikipedia.org/wiki/Blue_Pill%28malware%29
- Chkrootkit: http://www.chkrootkit.org
- Rootkit Hunter: http://htp://rkhunter.sf.net
- OSSEC: http://www.ossec.net
- Rootcheck signatures: http://www.ossec.net/rootkits
- RK Profiler LX: http://www.trapkit.de/research/rkprofiler/index.html
- Zeppoo: http://sourceforge.net/projects/zeppoo
« Previous 1 2 3 4
Read full article as PDF:
Expert_Security_Intro.pdf (1.06 MB)Tag Cloud
New Mint Minted
Version 16 of the popular Linux desktop reveals new tools, edge-snapping, and performance improvements.
New Worm Attacks Linux Devices
Symantec says Linux-Darlioz burrows in through PHP.
Project Sputnik Gets a Boost
Dell renews its quest for the ultimate developer machine.
Sneaky New Linux Attack Discovered in the Wild
Innovative back door looks like normal SSH traffic.
CeBIT Call for Papers
One of CeBITs most successful forums opens the new year with a new name. The popular Open Source Forum continues in 2014 under the name Special Conference: Open Source. This year, the forum will be bigger and offer a wider range of possibilities for sponsors.
Linus Announces Linux Kernel 3.12
New release offers better graphics drivers and expands filesystem support.
Dark Alliance Reinvents Email Security
New mail protocol will shut out the NSA and prevent snooping on metadata.
DDos Attack Map Charts Denial of Service
A new web application helps users visualize distributed denial-of-service attacks.
Saucy Salamander Gets Legs
Ubuntu 13.10 takes a step toward convergence, with lots of mobility, but Mir only partly here.
Intel and Arduino Create Pi-Like System
Galileo board is targeted to embedded developers and educational institutions.


text:
Program Name: MediaSanta DVD Maker Published By: MediaSanta Software Inc. License Type: Shareware Date Released: January 05, 2011
MediaSanta DVD Maker Desciption:
License: Shareware | Price: $29.95 | Size: 2.3 MB | Downloads (70) Platform: Windows MediaSanta DVD Maker Copyright notice: Pirated Software Hurts Software Developers. Using MediaSanta DVD Maker Free Download crack, warez, password, serial numbers, torrent, keygen, registration codes, key generators is illegal. We do not host any torrent files or links of MediaSanta DVD Maker from depositfiles.com, rapidshare.com, any file sharing sites. |
Related Software | |
New Downloads | Top Downloads | Top Search |


text:
Sun City Casino
- Phone
(Dennis Sabatino)
- Website
- www.suncitycasinos.com
- email@example.com
- Serving:
- Serving Los Angeles, Orange County and Inland Empire CA
We provide casino parties to inject an element of fun and excitement to any and all events! Whether your game is Craps, Blackjack, Roulette, Poker, or one of the many other casino games we offer, let us help you to create the most memorable night!
Social Media
We know that you have many choices when it comes to Casino entertainment, and in these tough times, it's hard to part with your hard earned cash! With all the choices, you may be wondering why you should choose Sun City Casino! Simply put, we care. We promise to combine value for money with the best equipment and dealers in the business. We make it our priority to make your event one that will be talked about for years to come.
With over 20 years' experience running successful casino parties; we bring with us experience and a wealth of knowledge on what it takes to make your party a huge success. Let us bring Vegas to you! We feature only the finest Casino Grade Tables and Equipment available - exactly like you would find at a Las Vegas Casino! We hire only the most experienced and personable Casino Dealers around!
The Sun City Experience
From expert preparation before your party begins, to careful closing down of your party down at the end of the night, we strive to bring you the best service possible. We work with you, and assign you a personal party manager to handle your party. This planner will be your single point of contact throughout the whole process of delivering your perfect party, providing tips such as how to maximize profits from a fundraiser, how to make sure everyone is included in a corporate event, and how to make the smallest house party seem like a huge Vegas event. We will work with you up to one month before your party to make sure that everything goes as planned.
We will provide a delivery crew to set up your casino party so that you don't have to waste time or energy before your event. Our delivery service also includes your very own personal pit boss for the night. Our pit bosses are expertly trained to make sure that your party is a roaring success and everything will be delivered and set up perfectly on time. We will work with you to plan a pre-arranged delivery time so that you'll know exactly when to expect the delivery crew to be there.
Party Time!
The time has finally come! You are now ready to experience the awesome magic of a true Sun City Experience. This begins with your professional dealers; your pit boss and your planner. Your guests will be amazed by our custom made Vegas style gaming tables complete with Vegas style bumpers that provide the most authentic look and feel.
Our games and tables
The most popular games that we offer are Craps, Blackjack, Roulette and Poker! We have all the most popular table games: Let-it-Ride, 3-Card Poker, Baccarat, Triple Shot Bonus, Blackjack, Poker - all versions, Caribbean Stud Poker and Pai-Gow Poker, Wheel of Fortune, Double Exposure Blackjack, Crazy 4 Poker, Spanish 21, and Texas Hold'em Bonus.
We offer our expert services for: Poker Tournaments, Monte Carlo Nights, Fundraiser and Charity Events, Grad Nights, Bachelor Parties, Poker Nights, Birthday Parties, Holiday Parties, Corporate Events, Reunions, Office Parties, Conventions and any other special event that you can conceive of!
There are currently no reviews for this vendor


text:
Marc by Marc Jacobs
Rosie Eyelet Top
Fashion legend Marc Jacobs introduced his diffusion line, Marc by Marc Jacobs, with a spring 2001 runway show. He has gone on to win seven CFDA awards including Womenswear Designer of the Year, Accessories Designer of the Year and Menswear designer of the year.
- 73% cotton 24% silk 3% poly
- Dry clean only
- Embroidered eyelet throughout
- Styled with Citizens Of Humanity Chloe Cut Off Short in Love Worn.
- Styled with House of Harlow Horseshoe Nail Cuff in Antique Gold.
- Styled with Giles & Brother Skinny Railroad Spike Cuff in Rose Gold Finish.
- Styled with House of Harlow Olbers Paradox Ring in Gold.
- Styled with Low Luv x Erin Wasson Temple of Poseidon Ring in Gold.
- Styled with Luv AJ The Plain Ring Tall (Set of 4) in Brushed Gold.
- Modeled in size S. See fit guide for model's dimensions.
- Revolve Style No. MARC-WS265
- Manufacturer Style No. M1131218


text:
Hook & Tackle has created the most unique Sun Protection long sleeve T-shirt to ever hit the fishing and boating market. Named the Solar System® Rear Vented Sun Protection T-Shirt, its Ultraviolet Protection Factor (UPF) exceeds 40. Its unique material feels very soft to the touch and it features a rear vent. Additionally, the Solar System Rear Vented Sun Protection T-Shirt, is odor-resistant and its moisture management properties wicks excess perspiration allowing you to keep cool and comfortable.
- 65% Polyester, 35% cotton Solar System weave
- UPF 40+ sun protection
- Odor-resistant
- Vented back for maximum air circulation
- Moisture management
- Hook & Tackle back logo
Product Specs
The West Advisor
The West Advisor articles have answered boaters' questions and provided solutions to boating problems for more than 20 years. West Marine has compiled one of the Web's most comprehensive collections of technical boating information articles.
Reviewed by 1 customer
Displaying review 1
- Comfortable
- Quality Materials
- Washes Well
Best Uses
- Outdoor Activities
Comments about Men's Rear Vented Sun Protection Tee:
My husband loves this shirt! He wants more for his birthday. Its hard to find an item that he wants two of! He says the fit is perfect and material is soft.
- Sizing:
- Feels true to size
Displaying review 1


text:
13 - 24 of 36
by: Cyrus
There have been a lot of Would You? candidates from Réunion Island lately. Something about the place that seems to breed richter surf chicks. Including this week's Would You? Emma Newschwanger.
Newschwanger is a very well accomplished longboarder who performs well in contests. This French beauty is sponsored by various European surf brands and competes on the ASP Europe Longboard Tour.
Emma Newschwanger: Would You?
Carissa Moore won her second career ASP Women's World Tou by: Cyrus |
Mick Fanning Wins Quiksilver P Mick Fanning defeated Gabriel Medina in the Finals to win t by: Cyrus |
Sally Fitzgibbons Wins Roxy Pr Sally Fitzgibbons defeated Tyler Wright in an all-Australia by: Cyrus |
Heavy Hitters Dominate the Ope The ASP World Tour's heavy hitters dominated rounds one a by: Cyrus |
Great Video Starring the Beaut Coco Ho is the total package. She's stunningly beautifu by: Cyrus |
Jake Marote is a surf photographer on the island of Oahu wh by: Cyrus |


text:
The Seaford Fire Department will be holding their annual Tree Lighting on Saturday December 1, 2012. The night of the Tree Lighting is filled with holiday spirit, this years Tree Lighting you will hear traditional holiday music from the Seaford High School's band and chorus. This year there will be a new performance from the Marianne Anderson School of Dance right before the ceremony will kick off. The ceremony will start at 6:30 pm with a few brief speeches then Santa will come to light up the Christmas Tree. Everyone is then welcomed to to come across the street for pictures with Santa and enjoy some hot chocolate and cookies. This event is a great way for the community to come together and enjoy a great night. We hope to see everyone there to celebrate the Seaford Fire Department annual Tree Lighting.
Seaford Fire Department Annual Tree Lighting
+ Leave a Comment
Corinne Graff
December 04, 2013 at 08:50 PM
This year, Ciara Charlotte will be returning for another performance @ 6pm!
- Wantagh-Seaford Patch Editor
- Edward Robinson
- firstname.lastname@example.com
Copyright ©2013 Patch. All rights reserved.


text:
The Longboat Key Club & Resort has agreed not to touch the guardhouse on Longboat Club Road as part of its $400 million renovation plan for Islandside.
But the road is still a point of contention.
The club dropped plans for the guardhouse after The Longboat Key Association, which owns and maintains the road, refused to sign off on the Islandside application.
But at a pre-application meeting between town staff and club officials held last month, Town Attorney David Persson questioned whether the club has the right to make minor changes to the road, including curb cuts and minor sidewalk modifications.
For more information, pick up a copy of the Thursday, May 7 Longboat Observer.
Currently 0 Responses
Resident keeps eye on the pie
Inspired by her mother's homemade banana cream pie, Bird Key resident Kim Manning had a sweet idea: key lime with a twist. -
Show us your spirit this season
This week, our reporters will make our final decisions on our favorite displays of holiday cheer for our "Spirit of the Season" contest. This year's competition isn't limited to lights. -
Paint the town red and green
This year, we won't just be on the lookout for the most festive holiday lights on the Key. We'll be on the prowl for anything that embodies the happiness of the holidays with our new "Spirit of the Season" contest.


text:
O.K I'm back ...... I've read on here that things seem too quiet since the change to Forum 3
O.K then let's make a reason for visiting more often, every day seems the aim.
A music game where you post between 4 and 10 words from the lyrics of a song (please keep to the last 60 years!)
Then someone has to answer with the song title and artist.
The correct guess/answer allows the respondant to then add their song choice 'words'
IF you make it too difficult and the answer has not been posted in one week, then as a penalty ('cos it involves work)
you will need to post the entire set of lyrics, song title and tell us who performed the version you had in mind.
Then you can have another crack .... but perhaps make it easier.
My Idea so I'm going first - any objections ? - over-ruled !!
"When I grow up I want a pony"
Over to you my music loving friends .................
Geoff T (See Admin should never have let me back in !!)


text:
To share this article: Enter the email address you want to send this article to in the field and click "Send"
By Sammy Batten Staff writer
A night of struggles for the Fayetteville FireAntz ended in a positive fashion Friday at the Crown Coliseum.
Fayetteville surrendered two goals to the Mississippi RiverKings in the opening four minutes and spent most of the night playing catch-up. But the FireAntz kept battling and outlasted the RiverKings, 4-3, in overtime.
Ben Contini scored the game-winning goal with 1:47 left. It was an important victory, as the FireAntz (27-14-3) pulled to within one point of idle Louisiana atop the Southern Professional Hockey League standings.
"That's not typical of us at all,'' said Fayetteville center Bobby Reed, whose goal on a pass from Brandon Richardson 51 seconds into the third period tied the score at 3. "We got off to a slow start. There were a couple of bad bounces they capitalized on, and we were down two goals.
"All you can do in that situation is chip away. Focus on the first one (goal), focus on the second one and keep going. Tonight was just a character win for us.''
Mississippi (18-21-7) and Fayetteville had only met once this season, with the RiverKings taking a 5-4 victory at home Jan. 3. They stunned the FireAntz on Friday when Matt Whitehead and Kevin Willer netted two quick goals on Kyle Rank.
But Fayetteville bounced back when SPHL scoring leader Josh McQuade produced his 36th goal on a breakaway 6:02 into the first period. Derek Elliott knotted the score at 2 at the 2:54 mark.
Chris Campanale put Mississippi back on top 3-2 late in the second period before Reed tied it in the third with his 13th goal of the season.
The teams appeared headed for a shootout before Contini struck for his sixth goal on assists by Elliott and defenseman Andrew Smale.
"I think we have a pretty strong lineup for the shootout, but we were happy to finish this in overtime,'' Contini said. "I think I had some luck on my side on the shot. But you take them any way you can.''
After a rough start, Rank finished with 43 saves in his third straight game in goal.
The FireAntz and RiverKings will tangle again at 7:30 tonight at the Crown.
Fayobserver.com is using Facebook Comments. You must have a Facebook account and be logged in to Facebook to post your comment below. Your comment is subject to Facebook's Privacy Policy and Terms of Service on data usage. Your comment will appear on our site and on your Facebook page unless you uncheck the "Post to Facebook" box. We expect users to maintain a civil discourse. If you believe a comment is inappropriate, you may click the X in the upper right corner to send an abuse report to Facebook. To report an objectionable comment directly to Fayobserver.com, email firstname.lastname@example.com. Want to know more? Check out our FAQ.


text:
The following were compiled from reports prepared by the Ukiah Police Department. To anonymously report crime information, call 463-6205.
DOG LOCKED UP -- Caller in the 700 block of Waugh Lane reported at 8:16 a.m. Friday that a neighbor's dog had been locked up for three days alone and was howling and barking. An officer responded and determined the incident was not as reported.
WELFARE CHECK ON DOG -- Caller in the 700 block of South State Street requested at 10:14 a.m. Friday that an officer check on an emaciated dog. An officer responded but did not find a dog.
WINDSHIELD SMASHED -- Caller in the 400 block of East Gobbi Street reported at 10:38 a.m. Friday that a neighbor's car windshield was smashed. An officer responded and determined a rock from the road possibly hit the window.
SERVICE DOG ATTACKED BY PIT BULL -- Caller at Safeway on South State Street reported at 1:45 p.m. Friday that a service dog had been attacked by a pit bull at the store. An officer responded and noted there were no injuries to the service dog.
FIRE AT WALMART -- Caller at Walmart on Airport Park Boulevard reported at 10:37 p.m. Friday that a group of transients had started a warming fire. An officer responded and arrested a 37-year-old Colorado man for being drunk in public.
DOG IN DISTRESS -- Caller in the 1000 block of North Oak Street reported at 11:30 p.m. Friday that a dog was in distress. An officer responded and determined the dog was fine.
The following were compiled from reports prepared by the Ukiah Police Department regarding calls handled by the Fort Bragg Police Department.
911 HANGUP -- A 911 call was placed from a pay phone at Fort Bragg Middle School Friday and dispatchers were unable to recontact the caller. An officer responded but did not find anyone at the pay phone.
DEAD DEER -- Caller in the 1100 block of North Main Street reported at 7:06 p.m. Friday that a dead deer was out front. An officer responded but was unable to locate the animal.
DUI ARREST -- An officer stopped a vehicle at the north end of Noyo Bridge at 2:59 a.m. Saturday and arrested Robert Alcala, 25, of Fort Bragg on suspicion of driving under the influence.
The following were compiled from reports prepared by the Mendocino County Sheriff's Office:
BOOKED -- Luis E. Monjarazrivera, 21, of Redwood Valley, was booked at the county jail Thursday at 12:49 a.m. on suspicion of possession of marijuana for sale.
BOOKED -- Pablo B. Mora, 52, was booked at the county jail Thursday at 7:41 a.m. on suspicion of battery against a peace officer.
BOOKED -- Randy D. Bloyd, 40, of Navarro, was booked at the county jail Thursday at 8:43 a.m. on suspicion of domestic violence.
BOOKED -- Gary L. Randal, 71, of Willits, was booked at the county jail Thursday at 2:19 p.m. on suspicion of penetration with a foreign object by force, oral copulation by force and engaging in three or more acts of substantial sexual contact with a child under 14.
BOOKED -- Luis A. Delgadillo Vincencio, 19, no city of residence given, was booked at the county jail Thursday at 3:02 p.m. on suspicion of hit-and-run with injury or fatality and being an unlicensed driver.
Those arrested by law enforcement officers are innocent until proven guilty. People reported as having been arrested may contact the Daily Journal once their case has been concluded so the results can be reported. Those who feel the information is in error should contact the appropriate agency. In the case of those arrested on suspicion of driving under the influence of an intoxicant: all DUI cases reported by law enforcement agencies are reported by the newspaper. The Daily Journal makes no exceptions.
The Ukiah Daily Journal reserves this space to correct errors or make clarifications to news articles. Significant errors in obituary notices or birth announcements will result in reprinting the entire article. Errors may be reported to the editor, 468-3526.


text:
WIN offers women in business networking opportunities with other businesses, participants and upcoming events. Learn more..
See what workshops, trainings and conferences are available to help your business. Learn more..
The SD CEO, Women's Business Center, provides training and business assistance to current and aspiring entrepreneurs from start-up to expansion. Learn more..
Register for SD CEO Events | Counseling | Student Internship Program | Support | Resources | Starting a Business | About Us
Women's Business Conference | Celebrating Women in Business
Women in Networking | Directory
Women in Networking Register online or by phone at 642-6435. Fee: $15 Includes Lunch. Register
QuickBooks Beginner An expert from Casey Peterson & Associates will present a day long class on how to use Quickbooks for your business. Register online or by phone at 642-6435. Fee: $199 Register
On Demand QuickBooks Webinars An expert from Casey Peterson & Associates will present 5 topics for QuickBook's beginner users. Each webinar is available online 24/7 per your convenience. Register online or by phone at 642-6435. Fee: $35 per webinar or $129 for the entire 5 webinar package. Register
CONTACT INFORMATION: SD CEO: Women's Business Center 1200 University St. Unit 9511 Spearfish, SD 57799-9511 OFFICE: Woodburn 216 Phone: 605.642.6435 Fax: 605.642.6344
The SD CEO is partially funded by the U.S. Small Business Administration. The support given by the U.S. Small Business Administration through such funding does not constitute an expressed or implied endorsement of any of the components or participants' opinions, products or services. SD CEO operates under Cooperative Agreement SBAHQ-11-W-0038 Reasonable accommodations for persons with disabilities will be made if requested at least 2 weeks in advance. All SBA programs and services are provided to the public on a nondiscriminatory basis. Accommodation will be provided to clients with Limited English Proficiency when required in advance. Contact Brittni Skipper at (605) 642-6435 or email email@example.com.
Copyright 2013-2014 by Black Hills State University |Terms of Use | Privacy Statement
Thursday, December 12, 2013 | Register | Login


text:
tw telecom, a leading provider of managed services, including Business Ethernet, converged and IP VPN solutions for enterprises throughout the U.S. and globally, has launched Dynamic Capacity, the second phase of its Intelligent Network service portfolio.
With tw telecom's Dynamic Capacity service, enterprise customers are able to scale their E-Line Business Ethernet bandwidth and capacity immediately across the network without service interruption through the same simple to use MyPortal interface they use for all tw telecom services. Dynamic Capacity is available to customers and prospects in approximately 16,000 tw telecom fiber-connected buildings in 75 major metro markets across the country.
"Dynamic Capacity allows customers to immediately scale up their network capacity in response to business activity peaks and demands, and then return to their original committed base rate as they choose, all without interrupting their network connections," said John Blount, Chief Operating Officer at tw telecom. "Imagine being able to increase network capacity in seconds. Dynamic Capacity customers don't have to imagine; they do it.
Our MyPortal feature also allows CIOs to see the cost impacts of these changes so the company can budget more closely and allocate costs more efficiently for a marketing promotion or other high bandwidth activity."
"To support the rapid proliferation of networked business applications, IT professionals increasingly need better real time visibility and control of their networks," said Erin Dunne, Director of Research Services, Vertical Systems Group. "A significant challenge is how to efficiently manage network bandwidth capacity in response to new Cloud apps or changes in existing applications. tw telecom addresses these needs with its Intelligent Network capabilities. Specifically, Dynamic Capacity is a unique capability that enables CIOs to look into their network metrics in real time and then allocate Ethernet bandwidth capacity on-demand."
The first phase of tw telecom's Intelligent Network, Enhanced Management, gives managed service customers access to critical performance data of the Ethernet or IP VPN services in a granular view, segment by segment. Dynamic Capacity is the second phase of the Intelligent Network giving E-Line Business Ethernet customers the ability to scale their bandwidth in real time. The third phase of the Intelligent Network, currently under development, will focus on providing managed service customers an applications aware networking capability so applications are able to be prioritized in real time while applying network resources in a flexible way to meet business needs.
"Our Intelligent Network is designed to provide customers with network capabilities, including bandwidth when they need it, where they need it and how they need it, and most importantly, in real time," Blount said. "The tw telecom Intelligent Network allows customers to automatically see critical performance data, add bandwidth, prioritize traffic, as well as enable customers to dynamically access best of breed Cloud solutions."


text: Support 88Nine And This Artist: Buy On Amazon Buy On iTunes DAVID BOWIELow Tracks By This Artist SOUND & VISION itunes SOUND & VISION Low Last Played on December 02, 2013 9:09am LIFE ON MARS? itunes LIFE ON MARS? Hunky Dory Last Played on November 14, 2013 12:59pm OH, YOU PRETTY THINGS itunes OH, YOU PRETTY THINGS Hunky Dory Last Played on September 08, 2013 1:44pm CAT PEOPLE itunes CAT PEOPLE Let's Dance Last Played on May 11, 2013 11:32am THE STARS (ARE OUT TONIGHT) itunes THE STARS (ARE OUT TONIGHT) The Next Day Last Played on May 03, 2013 9:17am View the discussion thread.


text:
You're watching...
Top presidential adviser fans flames of partisanship
Mike Emanuel reports from Capitol Hill
Jan 21, 2013
You're watching...
Mike Emanuel reports from Capitol Hill
Jan 21, 2013
Also in this playlist...
Auto-advance: ON
Auto-advanceThis transcript is automatically generated
Even on this day -- supposed unity.
Politics was really never far below the surface as you can imagine and a comment from one of the president's top advisors only seem to fanned the flames of partisanship even more.
Here's chief congressional correspondent Mike Emanuel.
The presentation of crystal inaugural -- to present Obama and Vice President Biden provided a charming bipartisan picture.
-- the debt ceiling gun control and immigration all on the agenda the second term honeymoon is likely to end quickly.
The president struck an assertive tone in his inaugural address.
We cannot mistake absolutism for principal.
The subject spectacle for politics.
Retreat name calling -- reasoned debate.
We must act knowing.
That our work will be -- perfect.
A long time top advisor to mr.
Obama says he wasn't calling out the GOP fact is that the Republicans in congress have been.
Defined by their actions and that's why they're polling numbers are.
So poor right now and why the congress is polling numbers are so poor right now but I don't think absolutism.
And I'm sure the president would say the same on the part of either party or any politician is helpful in terms of solving problems.
But in an interview with the Washington Post White House communications director Dan -- suggested mr.
Obama is worthy of the task but Republicans are not quote.
There's a moment of opportunity now that's important.
What's frustrating is that we don't have a political system or an opposition party worthy of the opportunity.
Pfeiffer told fox his quote was a message to the country not just a political parties.
But a key Republican senators sounded troubled by the tone.
Heading into a new term with a nation facing serious issues requiring leadership both parties need to figure out a way to work together.
To solve big problems for Democrats frankly they're gonna need some help from the president laying out what the issues -- -- the American people.
And providing them the ability to do what they know needs to be done even the political director of CBS news wrote in slate dot com and SA headline go for the throat.
Why Obama must declare war on the Republican Party.
And as he considered the second term John Dickerson concluded the president should go after the Republicans quote.
Obama's only remaining option is to pulverize.
The first test that is near -- will come in less than 48 hours that is -- the house is expected to vote to increase the debt ceiling.
Through mid may as part of that they will insist on the senate passing a budget.
Which is when things could get feisty again -- Mike thank you.
Filter by section


text:
FREE eNewsletterGreen Technology eNews delivers the latest news impacting technology in the Green industry each week. Sign up to receive FREE breaking news today! [Subscribe Now] |
Latest Green Technology News
- Box Continues Global Expansion With New Strategic Partners
- MakerBot Executives Personally Donate Funds to Support Education Initiative to Put a MakerBot Replicator 2 Desktop 3D Printer in Schools in America
- POZEN Clarifies Ex-Dividend Date for Previously Announced Special Cash Distribution
- Capella Education Company Initiates Quarterly Dividend
- Troux Helps Scottish Widows Investment Partnership Streamline Complex Business Environment
Featured White Papers
- Getting Smart on Analytics in the Contact Center - Measurement is the First Step in the Process
- Understanding Your Customers' DNA - The Key to Intelligent Connections
- Benefits of an SOE
- DOING MORE WITH LESS: How Red Hat Enterprise Linux shrinks total cost of ownership (TCO) compared to Windows
- 3 Must Follow Guidelines for Mitigating M2M Software Security Risks


text:
To be honest I had my doubts about the TARP TOOL when I first heard about it. I've never really had too many problems snapping down my cover, but I still wanted to give this product a fair look. Maybe it's because the idea is so simple, but for whatever reason I wasn't sure if the patent pending product was truly necessary.
It's quite small so I was able to take it with me on a recent work trip. I tried it out on a "seasoned" pontoon that had an older cover that appeared to have shrunk a little over the years. The TARP TOOL did make it a lot easier for me and getting that older cover back on was a snap, for lack of a better word.
It was nice not to put any stress on my fingers as I was able to snap the cover down as quickly as I could get to each snap. The working end is made of carbon-fiber composite materials and the handle is hardwood with a satin finish. I could tell that it was invented by a boater because if you accidentally drop it overboard, the TARP TOOL floats.
Marina owners interested in selling the TARP TOOL can contact the manufacturer about getting a counter display as well as private labeling with a logo or imprint on the tool itself. The TARP TOOL retails for $12.95, which isn't too bad. If your hands get sore snapping on your cover you'd probably pay double for something like this. It's also nice for those older covers where the snaps don't always seem to line up just right.


text:
Home | RSS Feeds |
Funny Pictures | Funny Videos |
Funny GIFs | YouTube Videos |
Text/Links | Channels |
User Rankings |
#29 to #15
itsmedumbass (10/15/2013) [-]
Hello fellow Whovian, I'm going to teach you something. In the magical and deadly universe that is FunnyJunk you must learn that there is a time and place to talk about Doctor Who. If you **** up with the time and place you will drown in a sea of red thumbs, and it will be of your own making.


text:
SKILLED LABOR - TRADES: Matanuska Electric Association is currently recruiting for several regular positions: SCADA Control More info |
MARKETING: Assistant/Associate Professor of Marketing The University of Alaska Southeast (Juneau campus) is More info |
BUSINESS OPPORTUNITY: Project Engineer ~ Palmer, AKResponsible to help plan, design, assess and oversee construction and More info |
ACCOUNTING: Corporate Subsidiary Controller Location: Anchorage Corporate Office JOB SUMMARY: Process acco More info |
FACILITIES: Incumbent will assess and evaluate and remediate current environmental risks being faced by tribal m More info |
EXECUTIVE: This position performs executive-level planning, organizing, directing and evaluation of departments More info |
GENERAL BUSINESS: Start Your Career In Property Management! Weidner Apartment Homes is currently looking for excep More info |
BUSINESS DEVELOPMENT: Electrical Engineer Applies design and electrical engineering skills to a variety of diverse an More info |
PHARMACEUTICAL: Advanced Nurse Practitioner Position Location: Alaska Relocation Assistance: Available FULL-TI More info |
SKILLED LABOR - TRADES: Electricians needed, Journeyman and/or Apprentice. Must have good driving record current electrical More info |


text:
You can also contact us at firstname.lastname@example.com
During your tour of Paris, you will drive along the elegant, tree-lined Champs-Elysees and past the Arc de Triomphe, viewing several perspectives of the Eiffel Tower.
Your tour passes the Place de Opera and the Pont Neuf - Paris ancient "New Bridge" on your way to the Ile de la Cite.
The foundations for the Cathedral of Notre Dame were laid in 1163. This supreme example of Gothic architecture boasts a facade divided into three levels.
The first level features three portals or main entrances, each adorned with intricately carved figures and biblical scenes. The cathedral's last great rose window, located above the Galerie des Rois, anchors the facades second level; the cathedral's soaring towers form the third level.
Notre Dame's interior, colored by light from the stained glass windows, inspires awe.
Photo opportunities will include the Eiffel tower and Place de la Concorde.
The Eiffel Tower, detested by all Paris upon its completion for the Exposition of 1889, celebrating the 100th anniversary of the Revolution, the tower was nearly razed in 1909 but was saved by the development of wireless radio. The first wireless telephones were tested on the tower in 1916.
Today, the Eiffel Tower is a beloved landmark.
Flowers and chestnut trees surround this beautiful square, Place de la Concorde, the scene of execution for thousands who perished during the terror of the French Revolution. Marie Antoinette and more than 1,000 other Frenchmen met their fate at the guillotine.
The famed Obelisk and the gates to the Tuileries make for two more photo possibilities.
Departures (Local Time)
9:00 AM (Hours: 11)
Activity Level:
4Duration: |
Hours: 11 |
Cost Per Person (Adult)
Tour Cost: $166.50
Tax/Other Fees: $18.50
Total Cost: $185.00
Be sure to bring your camera. You have time to browse for souvenirs among the shops near Notre Dame. Free time is allowed for lunch. Excursions listed for a port may not be available for every cruise.
At the cruise ship pier. The specific meeting location at the pier will be listed in your confirmation email and voucher for this shore excursion. See the 'Redemption and Voucher Details' section below.


text: My Grandmother was walking downstairs at 3am to let the dog out and she fell down the stairs and broke her ankle and her knee. I live the closest so she tried to call me and I didn't hear the phone my mom is next closest and she has just moved into a new house and had not hooked up a phone yet and all of their cells were in the kitchen, so she did not hear the calls either. So my Grandmother had to call my uncle who lives and hour away to come and help her, and had to lie on the floor waiting for him. I feel so horrible that I was not there for her. Well after they got her to the ER and she was casted and everything they go to get her up and give her crutches to send her home and they find out she is ot strong enough to use them. So she has to stay in the hospital for a while. They are also talking surgery for her knee down the line. My Grandmother is a diabetic and has always had trouble healing and I am just afraid of surgery with her. I don't know what to do. My mom was living with my Grandma until Saturday night and would have been there if it had happend before. I am mad at the realtor that claims she is tring to sell my granmothers house. It has been on the market for over a year, it is priced low for the neighborhood, one of the largest in the neighborhood, and this woman never wants to do open house she dosen't want to advertise the house. you know if she had sold this house my granmother would have been in a ranch and this would not have happend. I am just beside myself.


text:
No 20, Cornerswell Road
Penarth, CF64 2UZ, Wales
How to get here:
Rail: Penarth - Exit the station and head north, then turn left onto Stanwell Road. Continue across Grove Terrace onto Cornerswell Road; number 20 will be on the left, next to Yarn'n'Yarn. (0.4 miles, 5m) +
This location is private and has no or limited access only. This is a private residence.
Access: publicStatus: recognisableOutside
Enemy of the Bane (1)
Filmed: 9 Jul 2008
Bloomin Lovely.
Enemy of the Bane (2)
Filmed: 9 Jul 2008
Sarah, the Brigadier and Mrs Wormwood hide out at the shop.
Additional locations as the crow flies:
No 7 Machen Street (Turn Left): 0.04 miles.
Machen Street (Turn Left): 0.04 miles.
Wood Street (The Lost Boy): 0.05 miles.
Rudry Street (Turn Left): 0.07 miles.
Salisbury Avenue (The Nightmare Man): 0.17 miles.
Filming Reports:
8 Jul 2008: Photo Album - Filming for Enemy of the Bane, by Scott Frankton
9 Jul 2008: Photo Album - Filming for Enemy of the Bane, by Scott Frankton
Related Stories
Enemy of the Bane [8-9 Jul 2008]: Bloomin Lovely
Information, downloads, photographs and other media are provided for reference and for personal use only (planning visits etc.) - they remain the copyright of their respective authors and may not be duplicated on any other website or media without prior permission.
All screen captures are the copyright of the BBC and appear here as reference to illustrate the location in comparison with how it looked at the time of filming and the present day; no attempt is made to supercede this or any other copyright.
Page visited 2255 times


text:
Category: sdhg TV
About Abodes
It's a good thing I'm an attentive driver (well at least 99.9 percent of the time). As I was driving back to San Diego after the Thanksgiving holiday, the driver of a large red pickup with reindeer antlers decided to pull into my lane regardless of my presence.
Read more


text:
Reading Guides
Above The Thunder by Renée Manfredi: Questions, plus a reading group guide, with links to reviews, excerpt, author interview and author biography at BookBrowse.com.
Reading Guide QuestionsPrinter Friendly GuidePlease be aware that this discussion guide may contain spoilers! The introduction, discussion questions, suggested reading list, and
author biography that follow are designed to enhance your group's
discussion of the unforgettable Above the Thunder, an astonishing
debut novel which explores the subtle, treacherous line between living
and dying and captures in gorgeously rendered language the unexpected
entanglements of the heart that can transform a life forever.
Suggested Reading


text:
Shown are some of the birds you can see for free at the Brush Museum's Division of Wildlife Display that has information about the local habitat and the wildlife that abound in the Brush area. The display also has examples of the vegetation, along with birds that dwell in each type of habitat. (Katie Collins/News-Tribune)
The lecture, presented by Audubon Colorado Society biologist Angela Mangiameli, centered on the restoration project which encompasses a portion of land near Fort Morgan's Riverside Park.
Introduced by fellow biologist Pete Walker of Colorado Parks and Wildlife, Mangiameli acquainted guests to the newest chapter of the Audubon Colorado Society, the Audubon Rockies, which focuses their restoration efforts on areas in Colorado's foothills, eastern plains and in Wyoming.
The Audubon Rockies regional office looks forward to addressing needs in this new territory for them within the Central Flyway which encompasses a vast region lying between the valley of the Mississippi River and the Rocky Mountains.
On its western boundary, it is an important breeding area for waterfowl and the majority of birds that use it make direct north and south journeys from breeding grounds. The goal of Audubon Rockies is to connect people with nature through education and conservation programs, to protect wildlife and wild lands.
As a native of North Carolina and Texas graduate who received her master's degree in Wildlife Management, Mangiameli had a lot of help in getting acquainted with the eastern plains area of Colorado and is eagerly adapting to the west.
With a staff of just three-and-a-half as Mangiameli describes, finding time for projects can be hard, but with the help of so many volunteers and partnerships with other entities such as Ducks Unlimited and Colorado Parks and Wildlife, the project has seen fruition.
Initiatied in the spring of 2011 after receiving an anti-pollution grant from the Environmental Protection Agency in 2009, the South Platte restoration project has Mangiameli focusing on conservation for birds primarily, but the scope ties into related areas that will protect habitats for many forms of wildlife as well.
As a key piece that defines the eastern plains, the South Platte River also acts as an important area for many bird species and the project initiated with a first phase that included bird counts in the area.
"Birds themselves are great indicators of the health of the environment overall," said Mangiameli, who reported over 90 species of birds counted at Riverside.
The next phase of the project included the planting of native grass and shrubs at the trial site, a patch of nearly an acre of woodland along the South Platte at Riverside. With the help of many volunteers, including some Morgan County Boy Scouts, the brush there was mowed down and replaced with three different species of shrubs, including wild plum, buffalo berry and sand cherry varieties, along with 75 varieties of new plants.
During the program, Mangiameli presented some birding hot spots within the county for bird-watchers that includes the Brush Prairie Ponds. Well-known as a state wildlife area, the ponds are also recognized as an important bird area by Bird Life International. Morgan County's Sandhill (Rosener Reservoir) and Jackson Reservoir were also on the list of IBAs or important bird areas.
For those bird lovers out there who would like to get connected with more information, Mangiameli suggest logging on to www.coloradocountybirding.com to access an online database that allows users to pick their county and find local bird varieties within.
According to that site, Morgan County is one of the most frequently birded counties of Colorado's eastern plains.
Also, for more information on the Audubon Rockies chapter of the national society, visit them on the web at http://rockies.aububon.org.
Also at the regular monthly museum sack lunch program, local author and historian Dale Stinton made note that his book, "A Bit of Brush History" had sold out, but more copies will be made available near the week of June 11 and can be found at the Brush Museum, Brush Area Chamber or East Morgan County Library. The book is still being offered for free, with donations to the Museum encouraged.
To date, the book has brought in nearly $1,000 in donations to the Brush Area Museum and Cultural Center.


text:
Plan Modification
Procedures for Plan Modification & Amendment
A good plan is a living document that changes with time (hence the 3-ring binder so that we can insert new pages when changes are made). But we don't want to change the course flippantly, so the following procedures are included to ensure that some thought and public notice go into any substantive changes.
There are three types of changes to the plan: amendments, special exceptions, and minor changes. Changes to the plan can be proposed by anyone: a member of the public, students, faculty, or staff. Proposals for changes to the plan must be submitted in writing to the Trails Committee with a copy to the MPC. The proposal must include the reason for the change, what provision of this plan would require modification and in what way, and why the change is in the best interest of the University.


text:
Wouldn't keep runningModerator: Team Cub
Forum rules
Notice: For sale and wanted posts are not allowed in this forum. Please use our free classifieds or one of our site sponsors for your tractor and parts needs.
5 posts
• Page 1 of 1
Wouldn't keep runningI have a 65 cub that starts great but after running for a couple minutes it just stops. From this point forward it will start after sitting for 3-4 minutes, but then it will die again. I checked some of the things mentioned in an early post: vent in fuel cap, pulled carb plug and gas keeps flowing, opened gas valve all the way opened, but nothing seems to make a difference. I should mentioned that before this happened (previous usage) the engine would sort of rev ever minute or so, if other words the tractor would sort of vroom, vroom, vroom, vroom,VROOM and then repeat but it did keep running.
Re: Wouldn't keep runningDid you clean the metering jet? You also say you have fuel flow, but is is a good steady stream or a somewhat weak stream. If it doesn't flow full force it will starve for fuel and shut down. Once the bowl refills it will restart and repeat the cycle.
Sea salt is healthier only because it gets stuck in the holes of the shaker and you can't actually put it on your food.
Barnyard Bash CubFest May 30th - May 31st, 2014 Click here for info.
Re: Wouldn't keep runningI recently had what Barnyard described. It ended up being a large flake of rust obstructing the gas tank outlet. I had to back-feed air from the compressor into the gas tank and that solved the problem.
Re: Wouldn't keep runningI completely tore the carb apart and cleaned everything out. Nothing is clog and everything seems to be working fine. The gas flow seems steady to me and I even left it run for a couple minutes and it kept flowing. As barnyard said, it runs, shuts off and the bowl fills right back up and it starts again only to shut right off.
Re: Wouldn't keep running
You must not have a good heavy flow. The flow should keep up with the carb. Sea salt is healthier only because it gets stuck in the holes of the shaker and you can't actually put it on your food.
Barnyard Bash CubFest May 30th - May 31st, 2014 Click here for info.
5 posts
• Page 1 of 1
Who is onlineUsers browsing this forum: No registered users and 3 guests |


text:
Flower Power Chandelier
Designed by Annet van Egmond & William Brand
Flower Power chandelier features flowing, seventies' shapes that are set-off against large icicles, creating an exciting spectacle for the eyes. Breaking with the tradition of hand-crafting wires of steel, the cutting of steel plates into flower shapes led to the creation of Flower Power. Finish available in black, white and nickel. Fixture available in a round and oval shape, upside chandelier, suspension, ceiling flush mount, table and floor lamp version. Twenty 25 watt, 120 volt, JCD Type G9 halogen lamps included. General light distribution. Made in The Netherlands.47.2 inch diameter x 33.5 inch height.
Dimensions: 33.5"H x 47.2"W |
Lamp Source: Halogen |
Bulb: 20 x JCD/G9/25W/120V Halogen Bulb not included |
Dimmer: Incandescent |
About Brand Van Egmond
William Brand and Annet Van Egmond founded Brand Van Egmond in 1989 with the sole intention to create art without restraint. The Brand Van Egmond studio has become an international trendsetter in creating innovative, independant lighting designs. The handcrafted contemporary lighting sculptures radiate passion and emotion and leave a lasting impression. Brand Van Egmond obtained international fame 20 years ago with their first lighting sculpture, 'Chandelier' that has become an instant icon.


text:
Receptor (biochemistry)
This article may be too technical for most readers to understand. (May 2008) |
In biochemistry, a receptor is a molecule usually found on the surface of a cell, that receives chemical signals from outside the cell. When such external substances bind to a receptor, they direct the cell to do something, such as divide, die, or allow specific substances to enter or exit the cell.
Receptors are proteins embedded in either the cell's plasma membrane (cell surface receptors), in the cytoplasm, or in the cell's nucleus (nuclear receptors), to which specific signaling molecules may attach. A molecule that binds to a receptor is called a ligand, and can be a peptide (short protein) or another small molecule such as a neurotransmitter, hormone, pharmaceutical drug, or toxin.
Numerous receptor types are found in a typical cell. Each type is linked to a specific biochemical pathway, and binds only certain ligand shapes, similarly to how locks require specifically shaped keys to open. When a ligand binds to its corresponding receptor, it activates or inhibits the receptor's associated biochemical pathway.
Ligand binding changes the conformation (three-dimensional shape) of the receptor molecule. This alters the shape at a different part of the protein, changing the interaction of the receptor molecule with associated biochemicals, leading in turn to a cellular response mediated by the associated biochemical pathway. However, some ligands called antagonists merely block receptors from binding to other ligands without inducing any response themselves.
The structures of receptors are very diverse and can broadly be classified into the following categories:
- peripheral membrane proteins
- transmembrane proteins
- G protein-coupled receptors – Composed of seven transmembrane alpha helices. The loops connecting the alpha helices form extracellular and intracellular domains. The binding site for larger peptidic ligands is usually located in the extracellular domain whereas the binding site for smaller non-peptidic ligands is often located between the seven alpha helices and one extracellular loop.[1]
- ligand-gated ion channels – Have a heteropentameric structure. Each subunit of consist of the extracellular ligand-binding domain and a transmembrane domain where the transmembrane domain in turn includes four transmembrane alpha helixes.[2] The ligand binding cavities are located at the interface between the subunits.
- receptor tyrosine kinase – Functional receptors are homodimers. Each monomer possesses a single transmembrane alpha helix and an extracellular domain containing the ligand binding cavity and an intracellular domain with catalytic activity.
- soluble globular proteins
- nuclear receptors – Composed of a C-terminal DNA-binding domain (DBD) and a N-terminal ligand-binding domain (LDB). The LBD is composed of twelve alpha helices and an antiparallel beta sheet. The ligand binding cavity is buried within the interior of the LBD.[3]
Membrane receptors may be isolated from cell membranes by complex extraction procedures using solvents, detergents, and/or affinity purification.
The structures and actions of receptors may be studied by using biophysical methods such as X-ray crystallography, NMR, circular dichroism, and dual polarisation interferometry. Computer simulations of the dynamic behavior of receptors have been used to gain understanding of their mechanism of action.
Binding and activation[edit]
Ligand binding is an equilibrium process. Ligands bind to receptors and dissociate from them according to the law of mass action.
- (the brackets stand for concentrations)
One measure of how well a molecule fits a receptor is the binding affinity, which is inversely related to the dissociation constant Kd. A good fit corresponds with high affinity and low Kd. The final biological response (e.g. second messenger cascade, muscle contraction), is only achieved after a significant number of receptors are activated.
The receptor-ligand affinity is greater than enzyme-substrate affinity.[citation needed] Whilst both interactions are specific and reversible, there is no chemical modification of the ligand as seen with the substrate upon binding to its enzyme.
Agonists versus antagonists[edit]
Not every ligand that binds to a receptor also activates the receptor. The following classes of ligands exist:
- (Full) agonists are able to activate the receptor and result in a maximal biological response. The natural endogenous ligand with the greatest efficacy for a given receptor is by definition a full agonist (100% efficacy).
- Partial agonists do not activate receptors thoroughly, causing responses which are partial compared to those of full agonists (efficacy between 0 and 100%).
- Antagonists bind to receptors but do not activate them. This results in receptor blockage, inhibiting the binding of agonists and inverse agonists.
- Inverse agonists reduce the activity of receptors by inhibiting their constitutive activity (negative efficacy).
Constitutive activity[edit]
A receptor which is capable of producing its biological response in the absence of a bound ligand is said to display "constitutive activity".[4] The constitutive activity of receptors may be blocked by inverse agonist binding. Mutations in receptors that result in increased constitutive activity underlie some inherited diseases, such as precocious puberty (due to mutations in luteinizing hormone receptors) and hyperthyroidism (due to mutations in thyroid-stimulating hormone receptors).
Theories of drug receptor interaction[edit]
Occupation theory[edit]
The central dogma of receptor pharmacology is that drug effect is directly proportional to number of receptors occupied. Furthermore, drug effect ceases as drug-receptor complex dissociates.
Ariëns & Stephenson[edit]
Ariëns & Stephenson introduced the terms "affinity" & "efficacy" to describe the action of ligands bound to receptors.[5][6]
- Affinity: ability of the drug to combine with receptor to create drug-receptor complex
- Efficacy: ability of the drug-receptor complex to initiate a response
Rate theory[edit]
In contrast to the accepted occupation theory, rate theory proposes that the activation of receptors is directly proportional to the total number of encounters of the drug with its receptors per unit time. Pharmacological activity is directly proportional to the rates of dissociation and association, not number of receptors occupied:[7]
- Agonist: drug with fast association & fast dissociation
- Partial agonist: drug with intermediate association & intermediate dissociation
- Antagonist: drug with fast association & slow dissociation
Induced fit theory[edit]
As the drug approaches the receptor, the receptor alters the conformation of its binding site to produce drug—receptor complex.
Receptor regulation[edit]
Cells can increase (upregulate) or decrease (downregulate) the number of receptors to a given hormone or neurotransmitter to alter its sensitivity to this molecule. This is a locally acting feedback mechanism.
- Receptor desensitization[8]
- Uncoupling of receptor effector molecules.
- Receptor sequestration (internalization).[8]
Three types of transmembrane receptors can be classified into families based on the way they transmit information into the interior of the cell:[9]
- G protein-linked
- Ion channel-linked
- Enzyme-linked
Other transmembrane receptors include sigma receptors.
The entire repertoire of human plasma membrane receptors is listed at the Human Plasma Membrane Receptome.[10][11]
G protein-linked[edit]
G protein-coupled receptors (GPCRs) are also known as seven transmembrane receptors or 7TM receptors, because they possess seven transmembrane alpha helices.[12] Ligand activated GPCRs in turn activate an associated G-protein that in turn activates intracellular signaling cascades.
The GPCRs can be grouped into 6 classes based on sequence homology and functional similarity:[13][14][15][16]
- Class A (or 1) (Rhodopsin-like)
- Class B (or 2) (Secretin receptor family)
- Class C (or 3) (Metabotropic glutamate/pheromone)
- Class D (or 4) (Fungal mating pheromone receptors)
- Class E (or 5) (Cyclic AMP receptors)
- Class F (or 6) (Frizzled/Smoothened)
Ion channel-linked[edit]
Ligand gated ion channels also known as ionotropic receptors are heteromeric or homomeric oligomers.[17] Binding of a ligand to the ion channel results in opening of the channel to increase ion flow through the channel or closing to decrease ion flow.
An enzyme-linked receptor also known as a catalytic receptor is a transmembrane receptor, where the binding of an extracellular ligand triggers enzymatic activity on the intracellular side.[18][19]
Tyrosine kinases[edit]
These receptors detect ligands through their extracellular domain and propagate signals via the tyrosine kinase of their intracellular domains. This family of receptors includes;
- Erythropoietin receptor (Erythropoietin)
- Insulin receptor (Insulin)
- Eph receptors
- Insulin-like growth factor 1 receptor
- various other growth factor and cytokine receptors
Peripheral membrane[edit]
These receptors are relatively rare compared to the much more common types of receptors that cross the cell membrane. An example of a receptor that is a peripheral membrane protein is the elastin receptor.
Transcription factors[edit]
The ligands for receptors are as diverse as their receptors. Examples include:
Receptor | Ligand | Ion current |
Nicotinic acetylcholine receptor | Acetylcholine, Nicotine | Na+, K+, Ca2+ [17] |
Glycine receptor (GlyR) | Glycine, Strychnine | Cl− > HCO−3 [17] |
GABA receptors: GABA-A, GABA-C | GABA | Cl− > HCO−3 [17] |
Glutamate receptors: NMDA receptor, AMPA receptor, and Kainate receptor | Glutamate | Na+, K+, Ca2+ [17] |
5-HT3 receptor | Serotonin | Na+, K+ [17] |
P2X receptors | ATP | Ca2+, Na+, Mg2+ [17] |
Receptor | Ligand | Ion current |
cyclic nucleotide-gated ion channels | cGMP (vision), cAMP and cGTP (olfaction) | Na+, K+ [17] |
IP3 receptor | IP3 | Ca2+ [17] |
Intracellular ATP receptors | ATP (closes channel)[17] | K+ [17] |
Ryanodine receptor | Ca2+ | Ca2+ [17] |
Role in genetic disorders[edit]
Many genetic disorders involve hereditary defects in receptor genes. Often, it is hard to determine whether the receptor is nonfunctional or the hormone is produced at decreased level; this gives rise to the "pseudo-hypo-" group of endocrine disorders, where there appears to be a decreased hormonal level while in fact it is the receptor that is not responding sufficiently to the hormone.
In the immune system[edit]
The main receptors in the immune system are pattern recognition receptors (PRRs), toll-like receptors (TLRs), killer activated and killer inhibitor receptors (KARs and KIRs), complement receptors, Fc receptors, B cell receptors and T cell receptors.[20]
See also[edit]
- Ki Database
- Ion channel linked receptors
- Neuropsychopharmacology
- Schild regression for ligand receptor inhibition
- Signal transduction
- Stem cell marker
- Wikipedia:MeSH D12.776#MeSH D12.776.543.750 – receptors.2C cell surface
- ^ Congreve M, Marshall F (March 2010). "The impact of GPCR structures on pharmacology and structure-based drug design". Br. J. Pharmacol. 159 (5): 986–96. doi:10.1111/j.1476-5381.2009.00476.x. PMC 2839258. PMID 19912230.
- ^ Cascio M (2004). "Structure and function of the glycine receptor and related nicotinicoid receptors". J. Biol. Chem. 279 (19): 19383–6. doi:10.1074/jbc.R300035200. PMID 15023997.
- ^ Kumar R, Thompson EB (May 1999). "The structure of the nuclear hormone receptors". Steroids 64 (5): 310–9. doi:10.1016/S0039-128X(99)00014-8. PMID 10406480.
- ^ Milligan G (December 2003). "Constitutive activity and inverse agonists of G protein-coupled receptors: a current perspective". Mol. Pharmacol. 64 (6): 1271–6. doi:10.1124/mol.64.6.1271. PMID 14645655.
- ^ Ariens EJ (September 1954). "Affinity and intrinsic activity in the theory of competitive inhibition. I. Problems and theory". Arch Int Pharmacodyn Ther 99 (1): 32–49. PMID 13229418.
- ^ Stephenson RP (December 1956). "A modification of receptor theory". Br J Pharmacol Chemother 11 (4): 379–93. PMC 1510558. PMID 13383117.
- ^ Silverman RB (2004). "3.2.C Theories for Drug—Receptor Interactions". The Organic Chemistry of Drug Design and Drug Action (2nd ed.). Amsterdam: Elsevier Academic Press. ISBN 0-12-643732-7.
- ^ a b Boulay G, Chrétien L, Richard DE, Guillemette G (November 1994). "Short-term desensitization of the angiotensin II receptor of bovine adrenal glomerulosa cells corresponds to a shift from a high to a low affinity state". Endocrinology 135 (5): 2130–6. doi:10.1210/en.135.5.2130. PMID 7956936.
- ^ Secko D (2011). "Cell surface receptors: a biological conduit for information transfer". The Science Creative Quarterly (6).
- ^ Ben-Shlomo I, Yu Hsu S, Rauch R, Kowalski HW, Hsueh AJ (June 2003). "Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction". Sci. STKE 2003 (187): RE9. doi:10.1126/stke.2003.187.re9. PMID 12815191.
- ^ "HPMR - Human Plasma Membrane Receptome". Retrieved 2011-12-27.
- ^ Gobeil F, Fortier A, Zhu T, Bossolasco M, Leduc M, Grandbois M, Heveker N, Bkaily G, Chemtob S, Barbaz D (2006). "G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm". Can. J. Physiol. Pharmacol. 84 (3–4): 287–97. doi:10.1139/y05-127. PMID 16902576.
- ^ Attwood TK, Findlay JB (1994). "Fingerprinting G-protein-coupled receptors". Protein Eng 7 (2): 195–203. doi:10.1093/protein/7.2.195. PMID 8170923.
- ^ Kolakowski LF Jr (1994). "GCRDb: a G-protein-coupled receptor database". Receptors Channels 2 (1): 1–7. PMID 8081729.
- ^ Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin JP, Davenport AP, Spedding M, Harmar AJ (June 2005). "International Union of Pharmacology. XLVI. G protein-coupled receptor list". Pharmacol. Rev. 57 (2): 279–88. doi:10.1124/pr.57.2.5. PMID 15914470.
- ^ "Search for: gpcr". InterPro. European Bioinformatics Institute. Retrieved 2011-12-27.
- ^ a b c d e f g h i j k l Boulpaep, Emile L.; Walter F., PhD. Boron; Boron, Walter F. (2005). Medical physiology: a cellular and molecular approach. St. Louis, Mo: Elsevier Saunders. p. 90. ISBN 1-4160-2328-3.
- ^ Ronald W. Dudek (1 November 2006). High-yield cell and molecular biology. Lippincott Williams & Wilkins. pp. 19–. ISBN 978-0-7817-6887-0. Retrieved 16 December 2010.
- ^ Alexander SP, Mathie A, Peters JA (February 2007). "Catalytic Receptors". Br. J. Pharmacol. 150 Suppl 1 (S1): S122–7. doi:10.1038/sj.bjp.0707205. PMC 2013840. PMID 17279064.
- ^ Waltenbaugh C, Doan T, Melvold R, Viselli S (2008). Immunology. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 20. ISBN 0-7817-9543-5.
External links[edit]
- IUPHAR GPCR Database and Ion Channels Compendium
- Human plasma membrane receptome
- Cell surface receptors at the US National Library of Medicine Medical Subject Headings (MeSH)


text:
Open for Dinner, Tuesday through Saturday, 5:00 pm to 10:00 pm
34 Church Street, Winchester, MA 01890
Tel: 781-729-1040.
Farm to Table, Eclectic Italian. A Tavola, literally translates to "at the table", an expression used in Italy as a dinner calling to gather everyone around the table to enjoy delicious food and each other.
Born to be the more casual sister restaurant to Bistro 5, A Tavola serves an eclectic Italian menu featuring "Piattini". These small plates will be used to showcase an array of charcuterie, artisan cheeses, fish and vegetables, to pair perfectly with an exclusively Italian wine list.
Additionally Chef offers a children's menu, convenient to-go service, and unique catering options.
A Tavola is dedicated to serving only the freshest local ingredients; giving guests the best quality food while supporting local farmers. Chef also offers a selection of hearty and comforting handmade pastas and made-to-order risotto entrées for two.
For children, there is a dedicated menu that suits young palates and incorporates our fresh, local ingredients. A tasty and convenient to-go service will turn hectic weeknight dinners into an easy stop on the way home from work.
For catering, Chef will supply grand antipasto of cured meats, artisan cheeses and locally grown vegetables that are perfect for home or office entertaining. And, if you are looking to feed 25 or more, A Tavola also offers roasted whole pigs available for pick up or delivery. Our wine list features an all Italian wine program representing many regions and styles. In addition to bottles, wine is served in carafes called "quartino" (250ml or a 'quarter' of a liter). These glass and a half size servings are a perfect for sharing and experimenting different pairings.


text:
There are no products matching the selection.
Offering a wide range of helmet camera mounts, suitable for GoPro Hero and Hero2, Drift HD, Contour, Replay XD, Liquid Image to name a few. Covering all types of action sports, from watersports to motorsports, snow and more. For a custom head cam mount, try XSories.


text: European Painting before 1900, Johnson Collection Portrait of Sir Joshua Reynolds After the self-portrait in the Tate Gallery, London (N 889) Made in England, Europec. 1820 Copy after Sir Joshua Reynolds, English, 1723 - 1792 Oil on canvas Currently not on view Cat. 827 John G. Johnson Collection, 1917 |


text:
I think it was a one shot deal.
I think it was a one shot deal.
No no no, mister. She beat cancer. Why wouldn't she be in studio?
(I haven't a clue, I'm listening to Jocktober)
Welcome to the grand illusion
Come on in and see whats happening
Pay the price, get your tickets for the show.
But dont be fooled by the radio
The tv or the magazines
But theyre just someone elses fantasy
So if you think your life is complete confusion
Because you never win the game
Just remember that its a grand illusion
the first rule of Hate Club is Fuck You... ...yup, it's snowed here 7 times in the last 120 years
You mean that the only videos of her Sitting (not walking) is not proof enough that she is cured?
"I feel fantastic," she said. "I've been declared cancer-free for about three or four months now. It's just a matter of still recovering at home, past all that treatment that kept me out of the studio for this long. But I've been feeling really good."
Howard: "The show(AGT) will grow". - 6:50am 5/16/12
Howard: "NBC is Happy!" "100Million will watch". 7:35am 5/21/12


text:
BP Comment Quick Links
Happy Holidays from Baseball Prospectus! We'll have new content on December 26th.
February 20, 2013 Rumor RoundupFishing for CarpMike Carp, a victim of the Mariners' logjam at the corner positions and in the designated-hitter slot, was designated for assignment on Feb. 12. That kept him out Zachary Levine's Meeting of the Mariner DHs on Tuesday and should ensure that he will be en route to his third professional organization before the end of the workweek. Where might Carp be headed? Let's take a look… Carp should probably pack his bags Meanwhile, the clock kept ticking on the Mariners' 10-day window to find a new home for Carp, who hit just .213/.312/.341 last season, but smacked 12 home runs in just 313 plate appearances in 2011. A left-handed hitter, Carp has actually fared better against southpaws (.275 TAv, versus .254 against righties) in his brief major-league career, but his strikeout rate and poor defensive profile limit his value. Once thought to be a potential "above-average big league first baseman," Carp now seems destined to face annual roster battles and bounce between teams in need of corner-position depth each spring, unless he can regain the shine that has worn off his bat. As Nick Cafardo, the national baseball writer for the Boston Globe, pointed out yesterday afternoon, the Mariners must trade Carp by tomorrow night, and Zduriencik is reportedly fielding calls from three of his counterparts. Red Sox GM Ben Cherington is one of them, and Boston's connection to Carp goes back at least a month, to this tweet from Cafardo's Globe colleague Peter Abraham. Jeff Luhnow of the Astros and Terry Ryan of the Twins are also at least kicking the tires on a deal. The Red Sox' interest in Carp is difficult to gauge, because Cherington inked free agent Lyle Overbay to a minor-league pact earlier this month, seemingly addressing the lack of veteran depth behind new first baseman Mike Napoli. Boston also tacked Mark Hamilton onto its list of non-roster invitees in January, and with Mauro Gomez floating around, too, there is not much room for another defensively limited bat. Carp could give manager John Farrell a lefty backup to left fielder Jonny Gomes, but his reverse-split résumé casts doubt on the feasibility of that arrangement. Moreover, Farrell already has a strong candidate for the timeshare in switch-hitter Daniel Nava, who owns a .286 TAv versus northpaws in limited big-league action and showed impressive plate discipline last year. Houston also seems to have a glut at the positions where Carp can play, with Brett Wallace projected to start at first base, former first baseman Carlos Pena on track to be the team's first full-time designated hitter, and newly acquired slugger Chris Carter potentially in line for at-bats at both of those spots, as well as left field. That list also does not include the team's Rule 5 Draft selection, Nate Freiman, a 6-foot-8 first baseman who made a positive first impression on his skipper, Bo Porter. With no hope of contending in 2013, the Astros could stockpile low-cost talents like Carp and cross their fingers for a rebound to their erstwhile upside, but spots are hard to come by, even on Houston's gutted roster.
11 comments have been left for this article.


text:
September 07-09, 2010
August 24-28, 2010
What is decentralised wastewater treatment system? | |||
CSE has developed a "Policy Paper on Septage Management in India" as deliverable of Centre of Excellence in the area of sustainable water management under the Ministry of Urban Development. This document on septage management aims to assist the Government of India towards preparation of national level septage management policies and guidelines. Access to improved sanitation in urban India has risen but the management of onsite sanitation systems such as septic tanks remains a neglected component of urban sanitation and wastewater management. Septage, which is a fluid mixture of untreated and partially treated sewage solids, liquids and sludge of human or domestic origin, flows out of septic tanks and enters waterways or is generally disposed into nearest water body or low lying areas. This leads to serious health and environmental implications. This situation demands a well- defined regulation, guidelines and management strategy for septage in the country. The septage management approach, discussed in this report, is an effort to assure that septage can be managed in a responsible, safe, and consistent manner across the states.
The policy paper can also be viewed at the website of Ministry of Urban Development under National Urban Sanitation Policy
A way to manage septage in Shimla
CSE has submitted a report on septage management in Shimla as a part of its deliverable as Centre of Excellence in the area of Water Management under Ministry of Urban Development. Shimla city, being highly undulating encounter problems in laying conventional, gravity flow sewer lines that will connect each and every house in all residential areas.
July 06-09, 2010
May 11-14, 2010