text:
Tuesday, December 22, 2009
A Billion Little Experiments.pdf (application/pdf Object)
some very good points in this article
Radiation recall dermatitis -- Guarneri and Guarneri, 10.1503/cmaj.090320 -- Canadian Medical Association Journal
Includes potential for radiation recall and specific treatment therapies such as: 5-fluorouracil, hydroxyurea, vinblastine,
methotrexate, adriamycin, etoposide, tamoxifen, bleomycin, melphalan, paclitaxel, docetaxel, gemcitabine, pegylated liposomal
doxorubicin, interferon α-2b, antituberculous drugs and simvastatin.
Medical News: Abdominal Surgery Risky for Older Patients
These associations held for patients with cancer and other diagnoses, and for both elective and nonelective procedures (P<0.001).
Prevalence, Demographics, and Psychological Associations of Sleep Disruption in Patients With Cancer: University of Rochester Cancer Center-Community Clinical Oncology Program
Insomnia is prevalent, underrecognized, undermanaged, and understudied among patients with cancer receiving chemotherapy.
Monday, December 21, 2009
Sunday, December 20, 2009
Doctor and Patient - Holding Doctors Accountable for Medical Errors - NYTimes.com
Doctor and Patient - Holding Doctors Accountable for Medical Errors - NYTimes.com
Q. What is a major patient safety area that still needs to be addressed?
A. Ten years ago, we approached patient safety as a series of system flaws; we believed that most errors were committed by good competent people doing something no more complicated than forgetting a cellphone. But in the last few years some of us in the patient safety field have begun to feel uneasy about that approach. When there are reasonably safe standards available, what do you do when people simply don't adhere to them? At some point, it's no longer a "systems problem."
Saturday, December 19, 2009
A taxonomy of epithelial human cancer and their metastases
Worth reading
Friday, December 18, 2009
Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials -- Myung et al. 21 (1): 166 -- Annals of Oncology
no benefits, some risks:
Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials -- Myung et al. 21 (1): 166 -- Annals of Oncology
Cancer diagnostic assessment programs: standards for the organization of care in Ontario
related to:
Cancer diagnostic assessment programs: standards for the organization of care in Ontario
Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma pts
full free access: Journal of Ovarian Research:
Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients
Thursday, December 17, 2009
Urgent notice: Ovarian Cancer woman needs help - pls respond Vancouver, BC
An ovarian cancer woman is being discharged to home hospice care, however, her wishes are to die within an institutional complex hospice care facility. Physician hospice support would be required. Apparently these services are not available for patients/people with complex care. IF you can assist with these system issues please respond in an urgent manner.
Ovarian Cancer Update: Lessons from Morphology, Molecules, and Mice
full free access
Annexin IV is differentially expressed in clear cell carcinoma of the ovary
clear cell vs serous - potential biomarker
definition: Slacktivism - Wikipedia, the free encyclopedia
Note: this is a 'new' term maybe and was found through a non-profit organizations's poll - rather disparaging term considering volunteerism is a large focus of NP's wouldn't you think? Comments?
Slacktivism - Wikipedia, the free encyclopedia
Wednesday, December 16, 2009
1988 - CA 125 in the Follow–Up of Patients with Ovarian Cancer; Acta Obstetricia et Gynecologica Scandinavica - 67(1):Pages 53-58 - Informa Healthcare
Ca 125 in the Follow–Up of Patients with Ovarian Cancer; Acta Obstetricia et Gynecologica Scandinavica - 67(1):Pages 53-58 - Informa Healthcare: "It is useful for monitoring the course of chemotherapy, but normal levels do not rule out the possibility of persistent or recurrent disease."
NIH Consumer Health Request for Information
NIH Consumer Health Request for Information: "We would like to hear from you!
The NIH Office of Communication and Public Liaison (OCPL) and the NIH Director's Council of Public Representatives (COPR) have partnered to develop a Consumer Health Information RFI in response to a Directive by President Barack Obama to all Federal agencies calling for greater transparency, public participation, and collaboration.
In conjunction with the NIH goals for public input and effective dissemination of science-based health resources and information to the public, the RFI will provide insight and better understanding of the health information needs and information-seeking behaviors of NIH health consumer audiences. Information gathered will assist the agency in developing and disseminating health, medical, and scientific information to a broader variety of audiences."
How Do I Apply? - Application Process, Congressionally Directed Medical Research Programs
How Do I Apply? - Application Process, Congressionally Directed Medical Research Programs
How Do I Apply - Application Process
| |||||||||||
| Nomination Package Checklist
Endometrial carcinomas in women aged 40 years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopath
There are some very interesting pieces of information in this abstract (including ovarian/clear cell/endometrioid cell types:
Endometrial carcinomas in women aged 40 years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopathologic subset.
Tuesday, December 15, 2009
In conversation with Dr. Brent Zanke | BioTuesday
The founder and chairman of ArcticDx
What's the status of your colon cancer test?
Colo-Risk is undergoing clinical testing Colo-Risk is undergoing clinical testing in collaboration with McMaster University in Hamilton. The core intellectual property is owned jointly by Cancer Care Ontario, which runs provincial screening programs, and McGill University. There are additional pieces of IP that we are in the process of acquiring. And we're hoping it will be launched next year as the first product of its kind to predict an individual's risk of developing colorectal cancer.
The test combines your genetic predisposition to colorectal cancer with environmental risk factors like age, history of smoking and body mass index to come up with your life-time risk of developing the disease. So, if you're carrying genes that say you've got a 30% or 40% likelihood of getting colon cancer at some time in my life, you will be vigilant in early screening programs. If you could tell from your genetic makeup that you have a 1% chance, that would be in keeping with your risk of developing a lot of other things as well.
Cancer survival in Africa, Asia, and Central America: a population-based study : The Lancet Oncology
includes ovarian cancer
Physician Referral for Fertility Preservation in Oncology Patients: A National Study of Practice Behaviors
less than 50% follow guidelines
Monday, December 14, 2009
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
Note: This full free access paper is dated 2007 but has 2009 references including Li-Fraumeni Syndrome.
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
PharmaLive: Pfizer Extends Commitment to Help Unemployed Americans
PharmaLive: Pfizer Extends Commitment to Help Unemployed Americans: "Medicines Assistance for Those who Are in Need) patient assistance program for an additional year, through December 31, 2010"
ScienceDirect - Social Science & Medicine : Interpersonal perception in the context of doctor–patient relationships: A dyadic analysis of doctor–patient communication
"Interpersonal perception in the context of doctor–patient relationships: A dyadic analysis of doctor–patient communication"
Gene Variant That Increases Ovarian Cancer Risk Discovered
Gene Variant That Increases Ovarian Cancer Risk Discovered: "After eight years of searching, Gayther and colleagues found an SNP on chromosome 9 that was uniquely linked to ovarian cancer. Each of us has 23 pairs of chromosomes, each 'copy' in the pair comes from one biological parent.
In collaboration with the international Ovarian Cancer Association Consortium (OCAC) they confirmed the finding in another group of 7,000 women with ovarian cancer and 10,000 women without the disease. The samples came from women all over the world."
Sunday, December 13, 2009
SOCS1/p53: Scientists discover molecule that acts as natural cancer defense, Cancer Treatment
Scientists discover molecule that acts as natural cancer defense, Cancer Treatment
Scientists from Canada have found a natural defense mechanism for cancer prevention. Cytokines have long been known to produce diseases that include cancer, diabetes, and chronic inflammation. The new study identifies a link between the SOCS1 molecule and the p53 gene that is found to be lost among a majority of cancer patients.
The new research surprisingly showed the link between SOCS1 molecule and cancer. According to a lead author and Université de Montréal student, Viviane Calabrese The research team didn't anticipate that SOCS1 would turn out to be linked to p53, the master regulator of natural anticancer defenses. We were surprised to realize that SOCS1 was directly linked to p53."
Saturday, December 12, 2009
Woman wins damages after errors by Winchester hospital (From Hampshire Chronicle)
one of the very few lawsuits ever won in ovarian cancer (irrespective of country)
Friday, December 11, 2009
Thursday, December 10, 2009
MicroRNAs in Ovarian Carcinomas
Wednesday, December 09, 2009
Mantra 2009 programme conference outline including abstracts
A combined meeting of kConFab, Australian Breast
Cancer Family Study, Australasian Colorectal
Cancer Family Study, Australian Ovarian Cancer
Study, Family Cancer Clinics of Australia and New
Zealand & kConFab
Lynch syndrome: still not a familiar picture.
CASE PRESENTATION: A large Lynch syndrome family with 15 affected family members and involvement in 7 organs is reported. It illustrates a lack of awareness and knowledge about this hereditary tumor syndrome among doctors as well as patients. None of the described family members underwent presymptomatic screening on the basis of the family history.
red flags for familal forms of cancer susceptibility - excerpt
The general clinical features that raise the suspicion of a familial form of cancer susceptibility in a patient diagnosed with any type of malignancy include [1]:
* A cancer that occurs at an unusually young age compared with its usual presentation
* The development of multiple tumors in a single organ, or bilateral development in tumors in paired organs
* The development of more than one primary tumor of any type
* A family history of cancer of the same type or related type in one or more first-degree relatives
* A high rate of cancer occurrence in the family
* Cancer occurring in an individual or within a family with congenital anomalies or birth defects
Expanded Extracolonic Tumor Spectrum in MUTYH-Associated Polyposis
Duodenal polyposis occurred in 17% of cases; the relative risk (SIR) of duodenal cancer was 129 (95% confidence interval [CI]: 16–466), whereas the lifetime risk was 4%. The incidence of extraintestinal malignancies among cases was almost twice that of the general population (SIR: 1.9; 95% CI: 1.4–2.5), with a lifetime risk of 38%. We observed a significant increase in the incidence of ovarian, bladder, and skin cancers (SIR: 5.7, 7.2, and 2.8, respectively) and a trend of increased risk of breast cancer among cases. The median ages of onset of these 4 malignancies ranged from 51 to 61 years. In contrast to familial adenomatous polyposis, no desmoid tumors were observed, but sebaceous gland tumors, characteristic of the Muir-Torre variant of Lynch syndrome, occurred in 5 patients.
The relative risks for several extraintestinal malignancies increased in patients with MAP, but based on the spectrum of cancers (which overlaps with that of Lynch syndrome) and the relatively advanced age at onset, intensive surveillance measures other than frequent endoscopy are unlikely to be helpful to patients with MAP.
Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report
note fig. 2 and reference to ovarian cancer (?)
Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report
Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report
Tuesday, December 08, 2009
gene called MAGP2 -- not previously associated with any type of cancer -- was overexpressed in papillary serous ovarian tumors of patients
A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called MAGP2 -- not previously associated with any type of cancer -- was overexpressed in papillary serous ovarian tumors of patients who died more quickly. They also found evidence suggesting possible mechanisms by which MAGP2 may promote tumor growth.
VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE | Unique genetic pathology centre set to change the way we treat cancer
"...ovarian cancer is at least five distinct diseases..."
Patient Relations "Road Show" at University Health Network :: Vol. 12 No. 4 2009 :: Healthcare Quarterly :: Longwoods Publishing
Patient Relations "Road Show" at University Health Network :: Vol. 12 No. 4 2009 :: Healthcare Quarterly :: Longwoods Publishing: "Overall, across all sites, the results of our program have generally been positive; 53.9% felt that the in-service met their expectations, and 45.9% felt that their expectations were exceeded."
A Patient's Right to be Believed :: Essays :: Longwoods Publishing
A Patient's Right to be Believed :: Essays :: Longwoods Publishing: "When I speak at public events about the power of online patient stories for healthcare decision-making, some in the healthcare industry (clinicians and non-clinicians) dismiss these millions of narratives as meaningless chatter with no validity. Interestingly, they're more often accepted as truth when they praise healthcare providers; they're harder to accept when they're critical."
Morphologic Changes in Ovarian Carcinoma After Neoadjuvant Chemotherapy: Report of a Case Showing Extensive Clear Cell Changes Mimicking Clear Cell Ca
Morphologic Changes in Ovarian Carcinoma After Neoadjuvant Chemotherapy: Report of a Case Showing Extensive Clear Cell Changes Mimicking Clear Cell Carcinoma
Clinical Value of Morphometric and DNA Flow Cytometric Variables as Independent Predictors of Survival in Epithelial Ovarian Carcinoma: A 5-year Follo
Clinical Value of Morphometric and DNA Flow Cytometric Variables as Independent Predictors of Survival in Epithelial Ovarian Carcinoma: A 5-year Follow-up Study
Monday, December 07, 2009
Increased incidence of postoperative infections during prophylaxis with cephalothin compared to doxycycline in intestinal surgery
The SSI in the colorectal department increased from 19% to 30% (p = 0.002) when doxycycline was substituted with cephalothin and decreased to 17% when we changed back to doxycycline (p = 0.005). In the gynaecology department the surgical site infection rate did not increase significantly. Subgroup analysis showed major changes in infections in rectal resections from 20% to 35% (p = 0.02) and back to 12% (p = 0.003).
new expression - "in the fullness of time" 10,000 patients' data a click away - thestar.com
10,000 patients' data a click away - thestar.com
"As for the old paper files, eHealth's interim chair says: "In the fullness of time, we will be rid of them.""
Sunday, December 06, 2009
Expert questions continuing H1N1 vaccinations
(reference/search prior blog posting 'H1N1 and cancer' letter:
Safety of Bevacizumab in Advanced Ovarian and Müllerian Cancers: A Review: Abstract and Introduction
Safety of Bevacizumab in Advanced Ovarian and Müllerian Cancers: A Review: Abstract and Introduction
The Impact of Complete Surgical Staging Upon Survival in Early-Stage Ovarian Clear Cell Carcinoma: A Multi-institutional Retrospective Study
Although the study was a limited retrospective study, the impact of peritoneal cytology status was more important than complete surgical staging procedure in CCC patients. More effective treatment modality was warranted, especially for CCC cases positive for malignant peritoneal cytology.
Preoperative CA-125 Levels in 123 Patients With Borderline Ovarian Tumors: A Retrospective Analysis and Review of the Literature
From a clinical perspective, we believe, on base of the results of this study and the literature, that preoperative discrimination using CA-125 level is especially difficult between patients with stage I ovarian cancer and the group of patients with serous and/or advanced-stage BOTs.
Saturday, December 05, 2009
This test can spare women from chemo. But they can't get it here - The Globe and Mail
This test can spare women from chemo. But they can't get it here - The Globe and Mail
My response: some of the public's opinions which, as usual, were way off target to the original focus of the article: It's always a great transformation of opinion when those without a cancer diagnosis are diagnosed. It's very nice to know there are so many who believe in each paying for their own healthcare except...that's nice. But, envision your neighbour, your family member, your friend who cannot. Envision if it is your neighbour's child. Nice that we seem to have come to such a one-person self-centerness that we cannot see beyond the small picture of one.
Response: Does Morphine Stimulate Cancer Growth? | GeriPal - A Geriatrics and Palliative Care Blog
Does Morphine Stimulate Cancer Growth? | GeriPal - A Geriatrics and Palliative Care Blog
Response to the dialogues:
- Sandi Pniauskas said...
While the media and pharma are often criticized in situations such as this, there is the communication factor - good or bad. The value to patients of harm vs benefit is that the information is available and sufficient enough for patients to question, research and also take the information for discussion to their professional caregivers. The e-patient communities welcome dialogues but not in an exclusive setting which is absent their participation.
- December 5, 2009 8:57 AM
Friday, December 04, 2009
Radiation recall dermatitis triggered by multi-tar... [Anticancer Drugs. 2009] - PubMed result
Radiation recall dermatitis triggered by multi-tar... [Anticancer Drugs. 2009] - PubMed result: "Radiation recall dermatitis triggered by multi-targeted tyrosine kinase inhibitors: sunitinib and sorafenib"
Tumor type and substage predict survival in stage I and II ovarian carcinoma: Insights and implications
Note: there is supplemental data that can be downloaded (word document) which is attached to this abstract - see link to view
A subset of ovarian carcinoma patients with an excellent outcome can be identified based on tumor type (endometrioid or mucinous) and stage (Ia or Ib). Type is more reproducibly assigned than grade and identifies a larger cohort of women with stage I/II ovarian carcinoma with favorable outcomes (12.2% vs. 6.5%), and therefore is superior to grade in estimating risk of death from ovarian carcinoma.
Gynecologic Oncology : Sequential chemotherapy with carboplatin followed by weekly paclitaxel in advanced ovarian cancer: Results of a multicenter phase II study of the northeastern German society of gynecological oncology
Gynecologic Oncology : Sequential chemotherapy with carboplatin followed by weekly paclitaxel in advanced ovarian cancer: Results of a multicenter phase II study of the northeastern German society of gynecological oncology
AHRQ Patient Safety Network - Patient Safety Primers
AHRQ Patient Safety Network - Patient Safety Primers: "The culture of individual blame still dominant and traditional in health care undoubtedly impairs the advancement of a safety culture. One issue is that, while 'no blame' is the appropriate stance for many errors, certain errors do seem blameworthy and demand accountability. In an effort to reconcile the twin needs for no-blame and appropriate accountability, the concept of 'just culture' is being introduced."
Thursday, December 03, 2009
Senate Affirms Screening Mammography for 40-Year-Olds - in Washington
In a 61 to 39 vote, the Senate dealt a significant blow to the power and credibility of the U.S. Preventive Services Task Force (USPSTF), by essentially deciding to disregard the task force's recent recommendation that women under 50 shouldn't undergo routine mammograms....
Drug company contributes $9 million to B.C.'s fight against cancer
Research in ovarian cancer will focus on identifying new biomarkers for diagnostic purposes as well as therapeutic targets
Recreational physical activity and risk of epithelial ovarian cancer
CONCLUSIONS: Our findings are compatible with an overall reduction in risk of invasive epithelial ovarian cancer associated with recreational activity but suggest that this association may differ in women with different histologic types of disease. Inconsistent findings across studies that have considered histologic type indicate that this issue is not yet resolved.
Wednesday, December 02, 2009
James Kreppner's Obituary by the Toronto Star.
James Kreppner Death Notice
"KREPPNER, James Rudolf - March 6, 1962 to May 14, 2009 The world has lost an extraordinary human being. It is with profound sadness that the family announces the passing of James, a man possessed of a brilliant mind, gentle soul and tender heart, after a long, courageous and feisty battle with illness, on May 14, 2009, in his 47th year due to HIV and Hepatitis C-related complications...James was a highly respected, articulate and exemplary activist who represented the true meaning of fairness and kindness."
response to prior letter: HINI and Cancer
email response (better late than never) December 2, 2009 4:57 pm:
"Thank you for writing and bringing to my attention your concerns regarding the government's handling of the H1N1 vaccine roll out. As you are aware, the vaccine is now available to all members of the public.
Your views and comments are appreciated and helpful to my work as Leader of Canada's New Democrats.
Between the conflicting messages, queue jumping, and sole sourced contracts; we feel the federal government could have done a better job handling the distribution of the vaccine. NDP Health Critic Judy Wasylycia-Leis continues to be our lead on this issue and you can review her work by visiting: http://www.judywl.ndp.ca/news/health.
Looking forward, we will continue to press the federal government to take a proper role in helping Canadians stay healthy and providing access to treatment when needed through:
- promoting healthy living
- hiring and training more doctors and nurses
- creating a pan-Canadian home care program
- ensuring prescription medicines are affordable
If you are interested in our plans to improve health care in Canada, I encourage you to check for details here: http://www.ndp.ca/platform/healthcare.
Again, thank you for sharing your views and comments as they helpful to my work as Leader of Canada's New Democrats. All the best.
Jack Layton, MP (Toronto-Danforth)
Leader, Canada's New Democrats"
14-3-3σ, the double-edged sword of human cancers
Despite the above findings that 14-3-3σ expression correlates with and may predict poor prognosis of breast, colorectal, prostate, and pancreatic cancers, opposite observations have also been made in other cancers including endometrium [61] and ovary [30], where it was found that the absence or low expression level of 14-3-3σ predicted poor survival or showed no correlation (see Table 1). In another study of 192 cases of ovarian cancer patients, no significant correlation between 14-3-3σ expression and survival was found [62]. Thus, it is possible that 14-3-3σ in prognosis prediction is cancer type dependent, and more detailed studies on this issue will be needed.
In response to recent media: Does Morphine Stimulate Cancer Growth? | GeriPal - A Geriatrics and Palliative Care Blog
Please read the full article/discussion. Many questions were asked and responses given which may be helpful for many.
Over the last week Reuters, ABC news, MSNBC, BBC News, and more than 75 other outlets reported on how two "two new studies add to growing evidence that morphine and other opiate-based painkillers may promote the growth and spread of cancer cells." What was most shocking were the headlines used to promote the stories:
* Morphine 'might spread cancer' (BBC News)
* Morphine May Help Tumors Spread in Cancer Patients (US News and World Reports)
* Pain drug morphine may accelerate cancer growth (Reuters, ABC News)
* Common Pain Relief Medication May Encourage Cancer Growth (Science Daily)
Tuesday, December 01, 2009
Cochrane Collaboration meta-analysis: Erythropoietin or Darbepoetin for patients with cancer - meta-analysis based on individual patient data
The authors of this new meta-analysis concluded that ESA treatment shortens survival. They could not identify with certainty any subgroup of patients at either increased or decreased risk of dying when taking ESAs. With their doctors' help, cancer patients should consider the risks of taking ESA against the risks of a blood transfusion. Be aware, however, that uncertainties remain about the magnitude of each.
favourite quote of the day
"... if you are really effective at what you do, 95% of the things said about you will be negative." Scott Boras
(incompetent) Ontario Health Ministry press release: Improving Patient Care in Ontario
email to Minister:
Improving Patient Care in Ontario
December 1, 2009 2:13 PM
Ontario has passed Third Reading of Bill 179 that would improve access to health care for Ontarians by allowing care providers to use all of their training to perform their jobs and to work more effectively in teams. The proposed legislation would:
Expand What Health Care Providers Do
Health profession Acts (e.g., Nursing Act) under the Regulated Health Professions Act would be changed to allow providers to perform specific health care actions (controlled acts) or order diagnostic tests:
Health Care Provider
Proposed New Controlled Acts and Powers
Nurse Practitioners
* Apply specified forms of energy (e.g., diagnostic ultrasound);
* Set or cast a fracture or dislocation of a joint
* Prick or lance skin to educate a patient
* Tell patients their diagnosis
* Treat a wound
* Insert an instrument, hand or finger into certain body openings for assessment or rehabilitation of the pelvic musculature
* Order certain forms of energy (e.g., diagnostic ultrasound)
* Tell patients their diagnosis
* Give suppository drugs
* Place a tube in the nose or mouth of a newborn
* Take blood samples from fathers and donors
* Prick skin to check a patient's blood readings
Medical Radiation Technologists
* On the order of a physician be able to:
- perform procedures below the skin (e.g., give a needle)
- suction a tracheotomy
- put contrast media into certain body openings and artificial openings into the body
- put an instrument, hand or finger past certain body openings and artificial openings into the body.
Professional Practice Changes Regarding Drugs
Health professions Acts (e.g., Pharmacy Act) under the Regulated Health Professions Act would be changed to give providers the power to administer, prescribe, dispense, compound (mix), sell and use drugs as follows:
Health Care Provider
Drug Authorities Proposed to be Added
Chiropodists and Podiatrists
Give a patient certain substances by inhalation
Dental hygienists
Prescribe, dispense, sell or mix certain drugs
Sell or mix drugs (can already prescribe and dispense)
Give a patient any substance on the order of a physician
Prescribe, dispense, mix and sell certain drugs.
Nurse practitioners
Prescribe, dispense, mix and sell drugs without restrictions.
Prescribe certain drugs to manage patient health
Give certain substances through injection and inhalation to demonstrate their use or to educate patients
Give certain substances by inhalation as ordered by authorized persons (e.g., a physician)
Respiratory therapists
Independently give a patient certain substances by inhalation
Increase Ability to Order X-Rays
Regulations would be changed under the Healing Arts Radiation Protection Act to allow:
* Nurse practitioners to order any X-rays
* Physiotherapists to order X-rays subject to conditions
* David Jensen
Communications Branch
* Ivan Langrish
Minister's Office
* For public inquiries call ServiceOntario, INFOline
null(Toll-free in Ontario only)
* Media Line
Toll-free: 1-888-414-4774
Ministry of Health and Long-Term Care
© Queen's Printer for Ontario, 2008 - 2009 - Last Modified:December 01, 2009
Q & A transcript: Outlook: Fighting a smarter war on cancer - washingtonpost.com
"Outlook: Fighting a smarter war on cancer"
Cancers, infections, and endocrine diseases in women with endometriosis
"While ovarian cancer and melanoma were significantly more common than in the general population, breast cancer was surprisingly less common."
Video-assisted thoracic surgery (VATS) evaluation of pleural effusions in patients with newly diagnosed advanced ovarian carcinoma can influence....
Video-assisted thoracic surgery (VATS) evaluation of pleural effusions in patients with newly diagnosed advanced ovarian carcinoma can influence the primary management choice for these patients.
Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer
Monday, November 30, 2009
CureToday.com: Blogs - Kathy LaTour - Do you understand your diagnosis?
"'I literally wrote the book but it made no difference,'"
Just medicare: what's in, what's out ... - Google Books
This book is available free through Google books or can be purchased online.
Malignant Ascites Symptom Cluster in Patients Referred for Paracentesis
click on the pdf icon for full free access the paper
New Class of Platinum-Based Anti-Tumor Drugs, Bisplatinates, Demonstrates
New Class of Platinum-Based Anti-Tumor Drugs, Bisplatinates, Demonstrates Potent Anti-Tumor Activity and Ability to Overcome Resistance to Currently Available Platinum-Based Agents
Sunday, November 29, 2009
OCATS requires your help
H E L P!!! We know it's Grey Cup weekend, and Christmas is coming, and we've all got better things to do. But, imagine in the middle of all this our Ministry of Health, without any consultations or even contacting the doctors with urgent and critical issues CANCELLED the meeting where they promised they would finally have a solution for us.
Write to: The Honourable Don McMorris, Minister of Health, Government of Saskatchewan, Minister's Office, Room 302, Legislative Building, 2405 Legislative Drive, Regina, SK, S4S 0B3, Fax (306) 787-0237, email@example.com, email@example.com
John L. Marshall -- How health-care reform can cure cancer - washingtonpost.com
"At the moment, there is a giant disconnect between patients, the cost of care and the clinical benefit of the treatment -- a disconnect that has caused us to lose perspective. When it comes to cancer care, we're not getting what we pay for.
Cancer medicine is often regarded as an area of significant progress and clinical research, so we should be able to tell without much difficulty what kinds of treatment are valuable and what kinds aren't.
But given that 80 percent of my patients will die of their cancer, it's clear that we have not found an "optimum" therapy."
CBC News - Health - Ontario expands access to costly cancer drug
CBC News - Health - Ontario expands access to costly cancer drug
Ontario is expanding access to a cancer drug that was the subject of a scathing report by the province's ombudsman earlier this year.....
news item: see - Top 10 most common primary site cancers diagnosed with more than 1 cancer
my view: according to ACS stats, but I full expect that these numbers are very low estimates
Saturday, November 28, 2009
Social Media Use in the United States: Implications for Health Communication | Chou | Journal of Medical Internet Research
Social Media Use in the United States: Implications for Health Communication | Chou | Journal of Medical Internet Research
(full free access is available by registering with the site)
Aggressive Treatment of Ovarian Cancer Not Supported By Science
"To get the science to back-up the practice is something that really needs to be done," concluded Ms. Symecko.
EvidenceUpdates: Phase III trial of observation versus six courses of paclitaxel in patients with advanced epithelial ovarian cancer in complete ....
Phase III trial of observation versus six courses of paclitaxel in patients with advanced epithelial ovarian cancer in complete response after six courses of paclitaxel/platinum-based chemotherapy: final results of the After-6 protocol 1
Comments from Clinical Raters
This article clarifies a terrible doubt of gynecological oncologist: a consolidation treatment with six cycles of paclitaxel does not prolong progression-free survival or overall survival in patients in complete response after first-line paclitaxel/platinum–based regimens.
Oncology - Gynecology
Definitive answer on this question should come from a GOG trial that is currently still accruing. Consolidation remains an option, with conflicting Ph3 trial results.
Chapter 22: Ovarian Cancer - Cancer Network
Cancer Management Handbook, 11th Edition » Chapter 22:
Cancer Management: A Multidisciplinary Approach, 11th Edition (2008).
Chapter 22
Ovarian Cancer
Stephen C. Rubin, MD, Paul Sabbatini, MD, and Akila N. Viswanathan, MD, MPH


text: Add the ProFire 50 lb. Rotisserie Kit - for 27" grills to your grill so you can start roasting your favorite meals! This kit comes complete with a stainless steel motor, spit, mounting bracket, and forks. Just plug in the motor with the included 110v cord and start roasting meats up to 50 lbs.

subset: commoncrawl


text:
An armada of snow plows and salt spreaders are deployed on highways across the nation's heartland, working to stay ahead of a powerful winter storm that already is blamed for one road death.
Winter storm warnings have been issued from Colorado through Illinois, with as much as a foot of snow expected in several areas.
National Weather Service meteorologist Kelly Sugden says the storm is moving a bit slower early Thursday morning than had been previously forecast but that it was gaining strength and producing a mixture of snowfall, lightning and sleet showers.
Get the ingredients you need to cook with Rach all week long. | |
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text:
Defending his son Sooraj Pancholi is Jiah Khan's murder case, veteran actor Aditya Pancholi said that his son Sooraj was at a hotel with his friends when Jiah Khan died. Aditya came out in defense of his son when Jiah Khan's mother Rabiya Khan hinted that a close one of Jiah has murdered her daug
Sooraj Pancholi News
Another case of assault and infamous behavior has been registered against veteran actor Aditya Pancholi. On Tuesday, Adiya Pancholi lost her temper over Zee News female reporter when she questioned him about Jiah Khan's suspicious dead. According to the latest report, Aditya slammed the door in&n
Sooraj Pancholi who served 23 days in jail for abetting Jiah Khan's suicide finally broke his silence and said that he still loves Jiah Khan and doesn't mind if his name is associated with Jiah throughout his life. While giving an interview to the daily, Sooraj said, "I don`t mind if my name is asso


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Diplomat: Confidential report finds Iran shipping arms to Syria
U.N. report says Iran violating ban on weapons sales
A confidential U.N. report revealed Iran is exporting arms to the Syrian government in violation of a ban on weapons sales, the same day President Bashar al-Assad blamed the violence in his country on the work of foreign-backed fighters.
The draft report describes three seizures of Iranian weapons shipments, including two bound for Syria, within the past year, a Western diplomat told CNN on Wednesday on condition of anonymity. The official was not authorized to release details to the media.
The report was drafted by a panel of experts and submitted to the U.N. Security Council's committee that monitors sanctions against Iran, the official said.
The revelations came as al-Assad, in a rare interview, told Russia 24 that weapons in the hands of rebels were flowing into the country from neighboring Lebanon and Turkey.
"You can't simply close the borders and stop the smuggling, but you can reduce the flow," he said.
In recent days, violence has spilled over into Lebanon and Turkey, where thousands of Syrians have fled. At least one person was killed and an undetermined number were wounded Thursday in renewed clashes in the northern Lebanese city of Tripoli between factions supporting and opposing the uprising in Syria, Lebanon's National News Agency reported.
Al-Assad put the blame instead on the so-called Arab Spring in which popular revolutions toppled the governments of Egypt, Libya and Tunisia.
"If we take into consideration the developments in Syria, the events in Libya and other countries, for the leaders of these countries, it's becoming clear that this is not 'Spring' but chaos."
The successful Arab Spring movements inspired the uprising in Syria that began in March 2011 with protests calling for political reforms. It devolved into a revolt with an armed opposition amid a brutal crackdown by al-Assad's forces.
The United Nations estimates that at least 9,000 people have died in the 14 months of conflict, while opposition groups put the death toll at more than 11,000.
CNN cannot independently verify reports of deaths and violence because the Syrian government has severely restricted access by international media.
At least 20 people were killed Thursday in attacks across the country, according to the Local Coordination Committees of Syria, an opposition network that collects casualty reports and organizes anti-government protests. The deaths include 10 in the Damascus suburbs of Daraya and Douma, three in Idlib, three in Daraa, two in Homs, one in Raqqa, and one in Swaida, the LCC said.
Syria blames violence in the country on "armed terrorist groups."
Some such groups "continued perpetrating massacres and targeting law enforcement members and citizens, and vandalizing public and private properties" on Thursday, state-run news agency SANA reported.
Thirteen "army, law enforcement and civilian martyrs" were buried Thursday, SANA said.
It also said 72 people from Aleppo, Idlib, and Damascus "who were involved in the latest events but didn't commit crimes, gave themselves up with their weapons to the authorities Wednesday."
Opposition groups, including members of the rebel army, say al-Assad's government has been trying to mar their efforts with false accusations of links to terrorism.
While the rebel army says its ranks are populated by those who defected from Syria security forces, al-Assad labeled them criminals.
"It's not an army, first of all, and it's not free because they get their arms from different foreign countries," he said in the interview.
"That's why they are not free at all -- they are a bunch of criminals who have been violating the law for years and have been sentenced in various criminal cases. There are religious extremist elements among them, like those from al Qaeda."
Al-Assad dismissed the enormous international pressure put on him to end the violence and step down, vowing that Syria would not bow on any issue.
The United States, the European Union and the United Nations have targeted Syria with a number of economic sanctions targeting al-Assad and his government.
Al-Assad acknowledged the sanctions have had an adverse affect on Syria's economy.
"The world doesn't consist just of Europe and the United States, and we find alternatives which allow us to overcome these difficulties. We can support small and mid-sized business, the basic element of our economy is agriculture, and it's hard to affect it with sanctions," al-Assad said.
He also called a boycott of recent parliamentary elections by the opposition a failure.
"It seems to some people that if we conducted the reforms earlier, the situation would have been better now. It's not right for one reason -- terrorists spit on reforms. They are not fighting for reforms, they are fighting to bring terror," he said.
Meanwhile, the U.S. government distanced itself from a Washington Post report that said more and better weapons are making their way into the hand of Syrian rebels.
The newspaper, citing unnamed officials and opposition activists, reported the arms are being paid for by Persian Gulf nations and coordinated in part by the United States.
"The United States has made a decision to provide nonlethal support to civilian members of the opposition," Victoria Nuland, a State Department spokeswoman told reporters Wednesday. "... But with regard to any assertions with regard to lethal, we are not involved in that."
The United States has expressed reservations about arming rebels, citing division among the opposition.
Meanwhile, division among Syrian opposition groups deepened Thursday with the Syrian National Council, widely perceived by Western countries as the primary coalition for the opposition, coming under fire by a leading opposition activist group.
The LCC called the national council a "failure," saying it will withdraw from the group. The council has been under fire for failing to unify the opposition groups and bring in international support.
Copyright 2012 by CNN NewSource. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Code Location:
Ohloh Project Analysis
LedgerSMB is a free software double entry accounting and ERP system. Data is stored in a server-based PostgreSQL database with a web browser based user interface accessible from anywhere in the world. The system uses PL/pgSQL and Perl as its main languages. Screens and customer visible output are defined using Template Toolkit templates allowing easy and fast customization. For output its output in PDF format, LedgerSMB depends on LaTeX or TeLaTeX.
Also as of October 1, 2011 Ohloh disregards the XML files in doc/database because these automatically generated files are skewing the code analysis.
As of March 13, 2012, the addons repository has been split off onto a separate Ohloh entry, specifically to enable better line counts for a single version of LedgerSMB.
File Name | LOCs | Language |


text: 04/13/2013 FSU Goes on the Aerial Offensive in Annual Spring GameGold beats Garnet, 40-24, Saturday as the 'Noles' passing game -- and as a result, the quarterback battle -- steals the show at Doak Campbell Stadium. 04/12/2013 Preview: 2013 Garnet and Gold GameFlorida State's four-player quarterback battle takes center stage Saturday at 2 p.m. inside Doak Campbell Stadium. 04/11/2013 Seminoles.com Spring Football RoundtableRyan Pensy, Scott Kotick, Layne Herdt and Brandon Mellor from Seminoles.com share their thoughts on FSU's spring practices, which come to an end Saturday at the annual Garnet & Gold Game. 04/03/2013 Noles Get Back To PracticeThe Seminoles Returned to Practice on Wednesday afternoon. 03/16/2013 Spring-Practice Primer: Running Backs and FullbacksFSU moves on from the Chris Thompson and Lonnie Pryor era with four 'Noles in the backfield this spring: Devonta Freeman, Mario Pender, James Wilder, Jr. and Chad Abram. 2013 OUTLOOK:Explosive redshirt freshman running back who possesses the quickness, speed and burst to run both inside or outside and also has great power to run through tackles. Excelled last spring in 2012 as an early enrollee, but suffered a sports hernia injury which kept him out much of last fall. Should be a nice addition to FSU's ground game which returns four starters on the offensive line and two other experienced backs. 2012: Redshirt season. PERSONAL: Explosive four-star running back who possesses the quickness, speed and burst to run both inside or outside and also has great power to run through blocks...selected as a U.S. Army All-American...rushed 130 times for 1,543 yards (11.9 yards per carry) and 17 touchdowns as a senior...named first team all-area by the Fort Myers News-Press...named to the Florida Athletic Coaches Association all-district 19 Football Team... earned Associated Press' Class 6A all-state third team honors as a senior...rated the No. 72 player on the ESPNU 150 as well as the No. 8 running back, No. 16 player in the state of Florida and No. 38 player regionally... No. 66 on the Sporting News Top 125 of 2012... rushed for 2,261 yards and 32 touchdowns, averaging 13.87 yards per carry as a junior...has posted times of a 10.61 in the 100 meters and 22 flat in the 200 meters in track ... rated a four-star prospect by ESPN, Rivals and 247Sports and a five-star prospect by Scout.com ... rated the No. 4 running back nationally, No. 7 prospect in the state of Florida and No. 41 overall prospect nationally by 247Sports.com ... rated the No. 28 overall prospect and fifth-best running back by Scout.com... No. 4 running back nationally, No. 5 prospect in the state of Florida and No. 38 overall prospect nationally by Rivals.com...selected Florida State over Alabama, Maryland, Miami (Fla.), USF, Tennessee and West Virginia. |


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About this Blog: I am a designer living in Brooklyn, New York. I love anything to do with design, color and typography. I post things on Design Muse that inspire me and hopefully will inspire others.
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You're watching...
Mom in denial about son's disability: Normal or Nuts?
Dr. Keith Ablow weighs in
Dec 26, 2012
You're watching...
Dr. Keith Ablow weighs in
Dec 26, 2012
Also in this playlist...
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Yeah basically that's right in my normal or might not stop this question everyone asked once a -- and it's a question we ask every week with doctor -- apple and Dennis found his.
Successes Fox News contributor and psychiatrist doctor keep apple good to see you back tableau.
And good to see you are and let's tap start with the yet number one email mom in denial over son's disability my grandson is autistic he's three years old.
He gets great treatment but my daughter is still in denial about its conditions should never even admits he has a special conditions.
Is this normal.
Well it it's understandable.
Denial is understandable but it it isn't normal.
And people who loved.
Each other don't.
Each other in denial.
And so -- open to discussion and you say something empathetic like listen it's gotta be tough.
Living with and parenting a child with challenges and you can talk to me about it.
So you open up that line of communication in as gentle ways you can but you open it up.
All right doctor LO another.
Letters can and has -- more often than not whenever I see an emergency vehicle my heart starts pounding.
I get -- -- made it makes me think about someone being in trouble or someone hurt is this nuts.
Again and but he's normal even extreme sensitivity.
Is is normal but this is -- -- this is not normal.
This is something.
-- highly sensitized.
To the suffering of others and the question is.
What sensitize -- -- you've got to go back and figure out in your own life.
What left your -- so afraid that you can resonate with other people that the kind of gift but here it's a bit of a -- therapy.
Is the answer your psychotherapy.
You can give you that clarity it's like Jerry's girlfriend on -- -- just cries all the time he does not a photographer.
About everything -- everything that was next on because if -- three out of three nuts I don't think we've ever had three night.
Yeah well as the holidays are here here's it would be bad moment yeah yes here's a four -- I just got out of a relationship doctor -- -- and I thought he was the one now that we've broken up he's acting like he's my best friend.
What's going on -- is this normal.
Well this is.
It's normal.
Amount either way you think you're seeing -- -- We always want to -- each other when the romance leaves these relationships but in fact if he was the -- one.
And now the romantic part isn't there anymore well you should watch what's left should be the best friend part.
So he seems to be the real deal it's just that.
The romances gone for now that doesn't mean it's gone forever by the way you never know let's be honest though that deference is not gonna last much longer -- one whether -- what.
One of certain stage someone else that those phone calls won't be happening too much if you have a question for doctor outlawing I don't know about that log on -- and -- dot -- -- he can shoot it down you can email your thoughts doctor -- your questions right there he's an answer them every week here on the show.
All right we don't see you happy new year and all the best in 2013 yes and all of you should call an old boyfriend or girlfriend today local -- Life would love yes.
Well they see a good advice from doctor -- -- -- at all is that normal or was that not the -- anyway.
Couple pulls me into next year -- Day care -- -- -- next year.
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Friendly, well-run neighbourhood restaurant with warm Mediterranean décor and pretty, spacious terrace; hidden away beneath apartment blocks in a residential area. International dishes and Hungarian classics delivered in a delicate, modern manner; sizeable list of daily specials.


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This new dictionary is derived from the famous 1853 law dictionary used by Daniel Webster, Abraham Lincoln, and Justice Oliver Wendell Holmes, Jr. Relying on Bouvier's structure and original entries, Professor Stephen Sheppard of the University of Arkansas, has added thousands of new terms and rewritten the most appropriate of the original terms for the first complete revision of this essential dictionary in a hundred years.
The Compact Edition is available in Paperback and iOS App formats (optimized for both iPhones and iPads). Android App is coming soon!
I'm a part time 4L who has had to work in order to support my legal education. I worked for a few lawyers and have had to look up legal phrases and words dozens of times. Naturally I was hesitant to use the Bouvier Law Dictionary since I wasn't even aware it existed but it completely surpassed my expectations.
Thankfully I started to use Bouvier and was able to understand legal concepts which arose in my law classes and in legal practice. When I was working for a local attorney I was able to use the dictionary in practice and in the classroom. The Bouvier Law Dictionary provides the reader with clarity and that's the best a dictionary can do.
The Bouvier Law Dictionary is worth every cent as it provides a law student with everything they need to know in law school and in law practice.
- Matt F., UMASS Law
Get the latest news, product info and more Check out Insight, our marketing blog.Read more»
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Search Tags: Kevin Deeley
As agencies come to terms with cloud security, another barrier emerges
FedRAMP and other initiatives are helping CIOs become more comfortable with securing data and applications in the cloud. But changing the way agencies buy, manage and oversee technology is a bigger roadblock in moving systems to the cloud.
Tags: technology , cloud computing , cybersecurity , FedRAMP , GSA , DHS , Richard Spires , Justice , Amazon Web Services , Mark Ryland , Homeland Security and Defense Business Council , Jason Miller
Thursday - 03/07/2013, 05:24am EST


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Storm warning for Somerset (From This is The West Country)
Get involved! Send your photos, video, news & views by texting COUNTY GAZETTE to 80360 or email us
Storm warning for Somerset
5:30pm Friday 25th October 2013 in News By Newsdesk
WEATHER experts have issued a warning over the possibility a storm could hit Somerset over the weekend or at the start of next week.
Strong winds and heavy rain are forecast in the county, prompting the Met Office to issue an amber alert for wind in several parts of the South-West region.
Officials have warned people to be prepared for the risk of falling trees as well as damage to buildings and other structures caused by strong winds.
It is not clear exactly when the storm is expected to hit Somerset.
A Met Office spokesman said: "A strong, high-level jet is expected to engage warm low level air to give rise to a rapidly moving low pressure system later on Sunday.
"There is the potential for gusts of over 80 mph, especially on exposed coasts."
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Choose an answer to each of these four questions, then find out how you can change your reactions to kiss unnecessary angst goodbye.
While driving to the market, your car tire goes flat. You:
a) Take a deep breath, then change the tire yourself. Got to do what needs to get done!
b) Call your hubby or friend to vent your frustration and ask for help fixing the tire.
c) Fume while the tire is being replaced, then let it bug you for the rest of the day.
You burned the chicken just as your in-laws arrive for dinner. You:
a) Quickly survey your fridge and pantry, pulling together a backup meal.
b) Joke that youre no Rachael Ray, then call the local chicken joint or pizzeria for takeout.
c) Feel mortified. Thats the last time youll attempt to play hostess!
In a hurry, you grab your favorite pair of jeans. Yikes they are too tight! You think:
a) Oops! Its more of a skirt day, anyway.
b) Im bummed its time to lay off the creamy desserts.
c) Ugh! Anything I wear today is not going to look good.
The line at the post office is very long, but you have to mail a package. You:
a) Use the time you wait to write a to-do list and return a phone call.
b) Sigh and feel annoyed, but, hey, thats life.
c) Complain loudly to people around you about how inefficient some things can be.
Your results
Mostly As: Calm and Collected
Kudos to capable you, at ease with making last-minute changes! Want to take your ace problem-solving skills to the next level? Plan ahead. For example, tuck baby wipes into your purse for spills and cook make-ahead dishes for entertaining. And polish your positive outlook even more by learning a lesson from each predicament. So you dropped your phone in dishwater? Next time, let it ring during chores.
Mostly Bs: Panicked, Yet Proficient
Youre in tune with your emotional and practical sides. But try to gain more control over your physical reaction. Each time you stress out, your brain sends threat signals to body parts that control breathing, heart rate and adrenaline. Dont put yourself through unnecessary anxiety for minor upsets. As soon as you feel your heart racing, calm yourself with this simple exercise: Concentrate on a peaceful place thats all your own say, your backyard garden. Imagine yourself sitting in it or slowing walking in it.
Mostly Cs: Downright Frazzled
Mishaps and missteps often overwhelm you. Your heart tends to react first, instead of your head so decision-making abilities are compromised. When faced with a dilemma, ask yourself: Am I in danger? If the answer is no, focus on putting the scenario in perspective.
And ID your angst: Figure out the underlying cause, such as fear of being late, fear of disappointing others, fear of embarrassment. Zeroing in on your hot-button issue and the scenarios when you have felt similarly stressed will help you to see a pattern. Next step: Think through and write down various concrete ways you can deal with that negative pattern in the future. Keep that paper in your purse. This will give you rehearsed solutions, just what you need when stress makes it difficult for you to spontaneously weigh options.


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NP Rank:
Meteor Explosion Had As Much Power as a Nuclear Blast
A meteor that exploded over Russia this morning was the largest recorded object to strike the Earth in more than a century, scientists say. Infrasound data collected by a network designed to watch for nuclear weapons testing suggests that today's blast released hundreds of kilotonnes of energy. That would make it far more powerful than the nuclear weapon tested by North Korea just days ago and the largest rock crashing on the planet since a meteor broke up over Siberia's Tunguska river in 1908.
"It was a very, very powerful event," says Margaret Campbell-Brown, an astronomer at the University of Western Ontario in London, Canada, who has studied data from two infrasound stations near the impact site. Her calculations show that the meteoroid was approximately 15 metres across when it entered the atmosphere, and put its mass at around 40 tonnes. "That would make it the biggest object recorded to hit the Earth since Tunguska," she says.
Read More: http://newsdoors.blogspot.com/2013/02/meteor-explosion-had-as-much-power-as.html
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- Photos: 10
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4 bedroom semi-detached house to rent Old Church Road, Enderby, Leicester, LE19 2EE
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3 bedroom semi-detached house to rent Drummond Road, Enderby, Leicester, LE19 4QL
An extended three bedroom semi detached property in the popluar location. Accommodation comprises hallway with open plan living room with dining room and access to garden, fitted kitchen with utility room off, three bedrooms upstairs and bathroom. Rear enclosed garden and ample off road parking... More details ›
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3 bedroom terraced house to rent Enderby
A BEAUTIFULLY PRESENTED THREE BEDROOMED FAMILY HOME! This three bedroomed home which is presented to an immaculate standard throughout has accommodation briefly comprising: Entrance hallway, lounge / dining room, kitchen, downstairs w/c. First Floor: Landing, three GOOD bedrooms and a bathroom. O... More details ›
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Friends of Fancy Creek Range
Location: Tuttle Creek State Park,, Fancy Creek Range
Type: OPEN RANGE DAY
Date: Thursday, August 22, 2013
Contact: Todd Lovin, Park Manager
Phone No: 785-539-7941
Time: 10:00 am - 4:00 pm
Other Information:
Open Range day at Tuttle Creek State Park, Fancy Creek Range. Bring your guns and ammo and shoot. Range fees and state park vehicle permits required. Annual Memberships for the range will be on sale. Ear and Eye protection required.


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Hey! You responded to something I posted on /ic/ awhile ago, and it was some great critique that really kept me going. I've been feeling really inspired lately; enough to start up an account here and start a sketchbook page. I'd really appreciate if you could stop by every once in awhile and let me know what you think http://www.conceptart.org/forums/sho...00#post3399000 Its not the best art but it would mean alot to me if you stopped by every once in awhile to offer some suggestions/critique.
Hey, cheers for replying on my questions, i shall respond on there soon regarding the university of bolton course, it all depends on what you want to do really, if you want to purely do 2D art work, then i would avoid it. If you want to do 3D artwork then it would be great! The lectures are cool, the course is pretty good and the facilities are pretty good, but it is very centered around the 3D side of things. if you want to know more just ask
Do you do most of your work on the ipad?
momo here, :3
thanks for your advice on the tablet, i'm just afraid, that i had a very bad experience with a low budget graphic tablet once, it was very weird to use, was trembling / shaking and never reproduced the level of my paper drawings... i guess wacom is a professionnal choice so it may be better than my previous experience ! Any advice on how to get used to that kind of tool easier ?
Why hello there
hi, thanks for commenting my art. Painting digitally is a lot harder than i expected and implementing colour and tones from imagination seems like an impossible task. I would appreciate your help. Thank you
#1 muscle sailor
Registered User
Frelance Artist
Perfectly imperfect


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One thing Fox Rothschild family law partner Eric S. Solotoff has learned in the five years his practice group has run a blog is that clients are looking for lawyers in less traditional ways.
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Should Law Firms Have an App for That?
The Legal Intelligencer
July 25, 2013


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Most of us know enough about The Great Tribulation to know that we don't want to be a part of it, but whether we're a part of it or not in the end times, The Great Tribulation is an event we need to learn about, as it helps us to understand the justness of God, and culminates in the return of Jesus Christ. In the following message, "The Great Tribulation — The Beginning of the End," as part of the enlightening series, "Bible Prophecy Made Simple," Dr. Robert Jeffress starts to look at The Great Tribulation, a time that will be characterized by unprecedented calamity and disaster.
Begin and end your day in God's Word through Daily Light on the Daily Path. This timeless work links passages from both the Old and New Testaments, helping us to hear how all of God's Word speaks in unison to the themes of our everyday lives. This beautiful leather-bound devotional is something you will treasure this year and for years to come.


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FCS Diversity and Inclusion - PROPOSED RULE - MARCH 2011
Dear Mr. Van Meter,
Thank you for the chance to comment on the ways in which the FCS can better serve farmers and food producers: small and midsized, local and regional. By strengthening our these parts of our food production system, we truly strengthen our entire country.
I support your efforts to diversify the FCS loan portfolio.
As you figure out what should be included in FCS marketing plans, please include a strong commitment to adding local and regional food producers to the FCS board, a publicly available outreach plan for communicating and engaging with the larger community of local and regional food producers, and a plan for how to use FCS local and regional food producer financing (along with other public and private capital) to identify and assist/address infrastructure strengths and weaknesses (aggregation, processing,
distributing, etc.) in the local and regional food supply chain.
I see locally produced food as a growing strength which can benefit individuals, families, local communities and our entire country at every level. It deserves an carefully planned support system so that it can blossom and grow.
Linda Gardner Phillips
Linda Gardner Phillips
Mettawa, IL 60045


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It is no surprise that commodity trading advisors (CTA) had a tougher go in 2009 after what arguably was their best year ever in 2008, especially when measured against all other alternatives. But putting a finger on exactly why some managers did better than others is a little more difficult.
While it was a bad year for trend followers in general, several did well, and while some managers define themselves more for marketing purposes, it seems there are always trend followers who do well. It would be too time consuming for us to apply some sort of purity test to trend followers and absent that, we have to conclude that there is much greater diversification in the space than many give it credit for.
Based on conversations with numerous managers, traders who are extremely long term did better in 2009, as did those who allowed themselves some discretion. The Barclay Discretionary Traders Index was up 2.16%, while its Systematic Traders Index dropped 3.3%.
John Hummel, principal of AIS Futures Management, describes his program as trend following, but it is discretionary and very long term, which worked in his favor. His 2X-4X program returned 64.31% and his 3X-6X program returned 97.26%. He stayed in for the long haul, meaning he didn't catch the 2008 mid-year reversals but was able to avoid the chop of 2009. His programs have been long gold off and on since the market turned in 2000.
It was a year of unprecedented intervention, or at least proposed intervention, by government into markets. Several managers cited the Federal Reserve's quantitative easing decision as a major factor of market activity.
"The political situation is fragile," says Stanley Haar, whose discretionary agriculture program dropped a few percentage points. Haar, who trades off of fundamentals, was hurt by interventions that tilted the dollar/ag balance.
The Barclay CTA Index was down (-0.1%) for only the fourth time in its 30-year history. The index was down in the first quarter as numerous downward trends reversed course and it was down in the fourth quarter, specifically December, when the dollar reversed.
Oddly enough, concerns over sector correlation may have prevented even worse returns. Last year many managers noted that they had reduced position sizing as positive returns mounted and it became apparent many markets and market sectors had become highly correlated. And while most CTAs underperformed in 2009, you didn't see the type of negative returns in managed futures in 2009 that you saw in mutual funds and hedge funds in 2008, which may be due to managers being more cautious.
Jay Feuerstein, principal of 2100 Xenon, believes this may have helped keep losses down. Feuerstein dropped 7.56% in his managed futures program and attributed the tough conditions to choppy markets and the Fed's quantitative easing. When asked about the difficult conditions, Feuerstein simply produced a daily bund chart, which illustrated extremely choppy conditions. "Choppy markets hurt our mean reverting trades," he says.
And it wasn't just fixed income markets, but grains and energies that produced a lot of chop. Perhaps trends in metals, currencies and equity indexes could have offset the choppy markets if it weren't for the sharp reversals at the beginning and end of the year.
While the negative correlation of the dollar to almost everything caused some managers to be cautious, it provided opportunities for others. Discretionary trader Michael Frischmeyer noticed that traditionally non-correlated positions showed negative correlation and was able to treat them as a hedge. "Because I recognized the markets all ebb and flow together, I loosened my risk management a bit and allowed my positions to move adversely because I recognized the counterbalanced positions. I wasn't kicked out of positions as quickly, so it prevented me from being chopped up as much as if I carried normal stops," Frischmeyer says. His discretionary program returned 42.09% in 2009.
Niche managers did a little better as currency markets offered long-term trends against the dollar and equity indexes had an impressive rally following the March lows. Several extremely long-term traders produced solid returns by riding out the chop and avoiding the whipsaws.
Becker Asset Management made 39.59% in 2009. They trade a traditional trend following strategy along with a short-term counter trend strategy. Oddly enough, Becker earned more profits in its traditional trend following model. "We trade all the liquid U.S. futures markets except for energies," says John D. Becker. "We had money in currencies, interest rates, grains, gold and silver. There was not one home run. Profits were kind of spread out."
And while there appear to be quality short-term traders who have emerged in recent years, the best performers aren't coming from their ranks. One exception is Quantitative Investment Management (QIM), which produced a 31.81% return in its X3 program and seems to make money in all market conditions. QIM earned nearly all of its profits in equity indexes but managed to tread water in most other sectors despite taking a hit when the Fed announced its quantitative easing policy. "We [had a big drawdown] as the quantitative easing was announced," says QIM Principal Michael Geismar. "Government manipulation is not a good thing."
Pixley Capital Management produced returns of 32.98% with its short-term countertrend system. Pixley holds trades a couple days at a time and concentrates on stock indexes and currencies. While they are short-term and countertrend, their success may be most attributable to trading in the two sectors that offered the best long-term trends in 2009.
In 2008, it was easy to know who did well. If you followed trends, you did well. Last year's successful managers were an eclectic mix of niche managers, extreme long-term traders, short-term traders in the right sectors and discretionary traders who chose well. It demonstrated the growing diversity in managed futures.
When analyzing managers, we have learned that it is sometimes better to look at how they handle tough market conditions — how much they lose in reversals for example — than their returns when the market winds are at their backs. And while 2009 was a tough year for most CTAs for some obvious reasons (choppy markets) and some not so foreseeable actions (quantitative easing), the drawdowns for most managers were reasonable, particularly given the returns of the previous year.
Most managers we spoke with expect 2010 to be a better year, and it certainly could be, but there also is a good chance that unforeseen factors will again work against traders as the fallout of our economic crisis is far from over. But CTAs have always been a good play when large market dislocations occur, so chances are they hold the best potential for providing a hedge against the unforeseeable turns that undoubtedly will come as we work through the most severe economic crisis in several generations.
Paul (Bucky) DeMarco was following in his father's footsteps as a coffee trader on the Coffee, Sugar & Cocoa Exchange when a sting operation of floor traders in Chicago in the late 1980s convinced him that the floor might not be around forever and that he needed to pick up additional skills.
Fred Schutzman was first a student and then an instructor at the New York Institute of Finance, where he studied under and taught alongside famous technical analyst John Murphy.
The two were introduced when DeMarco took a class on technical analysis. "I was teaching the class and met Bucky," Schutzman says. "His desire was to learn more about technical analysis so he could trade better; my desire was to learn more about trading so I could apply my theoretical knowledge. Everything was nice in the text books but I always had in the back of my mind, 'can I make money with this.'"
DeMarco says, "Freddy and I are opposites. He likes peace and quiet, I am the trader, the extrovert and loud guy."
Despite their differences, the chance meeting began a 20-year collaboration and friendship that eventually led to the creation of Briarwood Capital Management.
"I remember our first trade. I told Bucky 'I am really bullish on 30-year bonds, let's buy it,' so he said to me 'if we are wrong, where is our stop?'" Schutzman says. "And I said 'Oh my gosh, I didn't think of that. I realized how much I had to learn. Technicians don't worry about being right or wrong, you just look at a chart and make a prediction."
That began a learning curve for both men, with Schutzman learning the realities of trading and DeMarco learning the intricacies of technical analysis.
The two worked well together and Schutzman would expand his studies to computer programming and begin to program their trading concepts. By 1996, they had a program and one customer and they would trade and optimize their method over the next five years. "It was a combination of discretionary and systematic, and by 2001 we were fully diversified and 95% systematic — we were professional at this point," Schutzman says.
The program launched in 2001, trading three systems: a long-term and two intermediate systems. Two of the systems are trend following in nature and the third system uses pattern recognition.
Schutzman is a fan of Jesse Livermore's pyramiding approach but was wary of the volatility. "We found that by trading three systems independently we are getting all of the benefits of pyramiding without the downside," he says. "The systems are buying it piecemeal. If the trend continues, we are adding to our winner. On the best trends hopefully we are fully invested and on the failed breakouts we have less than a 100% position."
The approach allowed Briarwood to be successful in 2009 despite a difficult environment for trend followers. Their standard low volatility program, which has more than $200 million under management earned 8.77% with the X2 program returning 22.02%.
"We are trading three systems. They enter and exit at different times," Schutzman says. "Ideally they should have drawdowns at different times."
The discretion comes in the form of a risk overlay borne of DeMarco's unease with holding positions too long. "Me being the floor trader, I have more of the shorter-term mind set," he says. "When markets go up hard, they often come down just as hard. We found that V tops and V bottoms are our worst enemies. It doesn't give our trailing stops enough time to catch up to price action, so we developed a risk management overlay that says if risk is too great, do something."
What they do is tighten up their trailing stops or take profits. Their approach is not complex but a combination of Schutzman's technical knowledge and DeMarco's trading expertise. "When I was a technical analyst all of the top technicians used simple stuff," Schutzman says. "Speak to any of the top traders and they tell you simple is better. If you can build something simple with very few parameters, that is likely to work well into the future," he says. And he should know. One of Briarwood's models only has eight lines of code but it helped them average double digit returns since 2001 with a solid risk profile and no down years.
Their approach isn't so odd after all.
It is no surprise that Financial Commodity Investments' (FCI) Credit Premium Program (CPP) did well in 2009 — most option writing programs had a good year — but it was also up in 2008, making it quite unique. FCI President Craig Kendall is a certified public accountant and longtime investor with a pretty good sense of timing. He exited real estate in 2006 and took profits in equities before the dotcom bubble burst.
As an accountant who had helped take a couple of companies public, he was amazed at the valuations he was seeing in the late 1990s and knew he needed to diversify his holdings.
In the early 2000s, he opened an account with famed option writer Max Ansbacher and became a protégé of his. What struck Kendall about the strategy after a conversation with Ansbacher was its simplicity, so he went about creating his own advisory.
"First of all, in futures you have increased leverage and if you take some risk, the returns can be commendable but managing the risk is ever so important, especially in options writing. I don't need to tell you that a lot of the competition is not around today," Kendall says.
So in 2003 he became a registered CTA and investment advisor. He launched his Options Selling Strategy (OSS) in 2004 and the CPP in 2006. What distinguishes both of his programs is that they trade a diversified group of markets instead of concentrating on equity indexes as most options writers do. Each program has roughly $10 million under management.
"There were a lot of options writers out there and I thought why not take the same strategy and diversify it across different commodities," Kendall says. "With this strategy we are really a short volatility play and there are times when the volatility on the S&P doesn't warrant doing credit premium selling because the risk/return just isn't worth it. But by doing the extra research and finding the volatility opportunities amongst various commodities [we find opportunities] to make good trades that can be a lot less risky than doing the S&P."
FCI trades energies, currencies, bonds and grains; all the major liquid markets. The downside to the diversified approach is that he is researching two dozen or so markets instead of one or two indexes. "You really have to monitor a lot more markets. [But] if we monitor all these markets and take only the safest volatility trades, we should have better returns for the clients with reduced risk."
Both programs are discretionary and look at both technical and fundamental inputs. The OSS sells mostly naked options two standard deviations out-of-the money. The CPP gets in on credit spreads and is always hedged.
"Prior to putting on any trade we have a predefined stop loss. If stuff moves against us we are pretty consistent with getting out," Kendall says. "What is discretionary is whether we roll up or whether we roll forward or roll out and we take that on a case by case basis although historically, nine times out of 10, we roll out and look for other opportunities."
Being hedged and diversified allowed the CPP to earn positive returns the last two years: 29.04% in 2009 and 6.94% in 2009. The OSS returned 38.91% in 2009 and lost 23.02% in 2008, still outperforming most programs in that space.
OSS got caught in the extreme volatility in 2008, says Kendall. "We went back and looked at the volatility. We are not poker players and in 2008 it became a poker game. Right now when volatility explodes to those levels we just sit on the sidelines. We let all those opportunities pass."
The upside to writing options across a diversified group of markets is that you can afford to be choosy. "Volatility shifts from time to time," Kendall says. "Last year we did a lot of energies, this year it has been currencies and Treasuries. We follow the volatility opportunities."
FCI will have about eight positions on at a time, in markets with the best risk/reward profile. "Our best success is when we wait for the opportunities to come to us," Kendall says. "The best trades are when we wait and catch extreme volatility."
That happened in sugar in 2009. "Volatility really exploded. We were selling calls but we waited until we got to high prices." Kendall says his programs are well suited for current uncommon market conditions; based on his timing and track record he may be right.
For many people, the exponential growth of commodity index funds has been cause for great consternation. But from a traders perspective the changes in the nature of commodity markets, particularly in spreads, that the funds caused provided great opportunity.
Emil van Essen created a program in 2007 to exploit those opportunities, which he has done to the tune of 218% since launching. He earned 28.88% in 2009 and his assets under management ballooned above $100 million.
Van Essen noticed how the growth of index funds and commodity exchange trade funds throughout the middle part of the decade became a dominant force on commodity markets. "I looked at how we could take advantage of their behavior and their size. We were looking at how they rolled their positions and also how a lot of participants were front running the roll of the index funds and trying to get in front of that whole wall of money, essentially we were [front running] the front runners," van Essen says.
When long only commodity index funds roll they sell the front month and buy the next contract, and a front runner sells the spread (bear spread) in front of them.
However, van Essen's program is more complex than simply placing bear spreads in front of the Goldman roll. He modeled every aspect of commodity spreads and found multiple ways to exploit anomalies in that relationship. "Spreads are much more consistent in their behavior and it is a lot easier to take advantage of the nuances of spread markets," he says. "Our ability to capture alpha in this market became a combination of getting an edge by front running the front runners in the index funds and also being able to model the markets to take advantage of price movements."
"We were modeling this wave of money. If the long only funds roll through a nine-day period, when are the front runners starting to put on their positions? And how could we model [it to] get in front of that movement of money so we can put on our positions and let all of those front runners push it in our direction," van Essen says.
He found that he didn't always have to wait for the rolls to realize profits."A lot of markets that have a lot of noise end up spiking and then reverting back to the mean," he says. This allowed van Essen to profit long before the major index rolls and, at times, exploit one roll period multiple times. "If we know that a market is mean reverting we can sell the spread on a spike and then if it gets back to the mean just take a profit and wait for another spike. And if it doesn't come back right away we can wait for the roll period to bring it back."
This is valuable because one criticism of the bear spread strategy is that it can act like an options writing scheme, producing consistent profits for a while and then a huge drawdown when a significant commodity shortage occurs. This happened in October 2006 when a wheat shortage in Australia caused a spike in the front month wheat contract and bear spreaders lost millions. By getting in earlier and on occasion taking profits early, van Essen avoids some of this risk. He has also deleveraged the program from it original format. The 2009 return is based on using approximately one third the leverage of when he started in 2007. Van Essen is also adding an additional risk overlay that will take small offsetting futures positions in case of a sharp rally. "We found that all of our drawdowns were the results of spikes in the [front month] market," van Essen says.
Constantly updating research is important because contango markets and front running bear spreaders create a drag on the performance of the index funds and indexers are looking for ways to alter their indexes to reduce these headwinds and create a smaller footprint. But van Essen is not worried it will affect his program. "I love when these guys do this because they are still rolling in a kind of dumb way. They have a standard way of operating and the more they try and change it, we will know exactly what they are doing and we will just be in front of them."
Van Essen has researched how spreads work, so if the phenomena of the index funds changes, either due to demand or new regulation, his strategies likely will still produce profits. "We have spent a lot of time and money over the last few years building models for how to trade spreads. We have state of the art models [and] more than half of our alpha comes from modeling the spreads before a roll ever takes place."


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The 12 steps to designing a strategic security process
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Executive Summary
Building an effective security program for your organization requires a highly structured approach. This overview, written by Rich Schiesser, in conjunction with Harris Kern's Enterprise Computing Institute, lists fundamental steps you can follow to establish a framework that consists of an executive sponsor, a security process owner, review boards, and cross-functional planning teams. Once these roles are defined, you can inventory your current tools and policies and chart the goals, requirements, and priorities that will allow you to develop a comprehensive security strategy.Join the discussion of this download.
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Aw, now there is a bit of creepy I am going to miss poking fun at. Scarlett Johansson and Sean Penn have split according to a source who blabbed to People.
Reps for both Scarlett and Sean have given the old IMMA NOT TELLIN' while waving questions about their relationship away. The source insists that Scarlett has packed up her skinny jeans and exited stage left. No rumored reason accompanied the split story, but I am guessing it probably has something to do with finding Penn face down in a Russian hooker.


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Browned Italian sausage and onion added to chicken stock, cannellini beans and Parmigiano-Reggiano cheese result in a rich, flavorful soup. Serve with toasted Italian bread topped with more cheese.
1. In a large saucepan, heat oil. Add sausage and onion; cook and stir until sausage is lightly browned, about 5 min.; drain off fat.
2. Cut rind off Parmigiano-Reggiano wedge; reserve cheese. Add rind, stock, and beans to sausage mixture. Bring to a boil; reduce heat and simmer, covered, until sausage is cooked through and cheese rind is tender, 10-12 min.
3. Meanwhile, thinly shave half the Parmigiano-Reggiano wedge; crumble remaining cheese and reserve both. Remove cheese rind from soup and cut in small cubes; return to soup along with escarole. Bring to a boil.
4. For service, ladle soup into bowls. Place one toast slice in the center of each serving. Top crostini with Parmigiano-Reggiano shavings; sprinkle crumbled cheese on soup.


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One look at this fashion awards arrivals and it's obvious all the celebrities came out with a mission to look fabulous and make a statement. We love all the eye popping colours and even Lady Gaga's green wig. Looking at the pictures just makes us wish we were there too - the purple carpet and Swarovski backdrop certainly made this one of the best displays at an event in 2011.
Vote for your favourite looks at http://styleme-up.com/polls/fab_or_drab.html
Lady Gaga
(L-R) Cameron Silver, Michelle Harper and Rod Keenan
Designer Donna Karan
Actress Marcia Cross
Actress Lucy Liu
Actor Gerard Butler
Chanel Iman and Lubov Azria
Kanye West
Alessandra Ambrosio
Designer Cynthia Rowley and actress Amanda Heard
Designer Philip Lim(L) and guest
Designer Zac Posen and model Sessilee Lopez
Model Sessilee Lopez
Whitney Port
Designer L'Wren Scott
Actress Chloe Sevigny
Actress Jessica Alba
Designers Keren Craig and Georgina Chapman
Actress Carla Gugino
Behati Prinsloo
(L-R) Ashley Greene, designer Michael Kors and Miranda Kerr
Actress Kerry Washington and designer Francisco Costa
Hilary Alexander
Designers Ashley Olsen (L) and Mary-Kate Olsen
Joy Bryant (L) and designer Rachel Roy
Anderson Cooper
Angela Bellotte and Russell Simmons
Pamela Love
Chanel Iman
Michelle Harper


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Pterorana Kiyasetuo and Khare, 1986, Asian J. Explor. Sci., 1: 12. Type species: Pterorana khare Kiyasetuo and Khare, 1986, by monotypy.
None noted.
As for the single species.
Placed in synonymy (as a subgenus) of Rana by Dubois, 1992, Bull. Mens. Soc. Linn. Lyon, 61: 329, but ranked as a genus by Chanda, Das, and Dubois, 2001 "2000", Hamadryad, 25: 108, on the basis of species autapomorphy. Frost, Grant, Faivovich, Bain, Haas, Haddad, de Sá, Channing, Wilkinson, Donnellan, Raxworthy, Campbell, Blotto, Moler, Drewes, Nussbaum, Lynch, Green, and Wheeler, 2006, Bull. Am. Mus. Nat. Hist., 297: 251, retained Pterorana as a genus pending its phylogenetic placement. Ao, Bardoloi, Ohler, and Grosjean, 2006, Alytes, 24: 22-39, discussed the morphology of the taxon and suggested that it is a member of the subsection Hydrophylax by possession humeral glands, but within this subsection excluded from Sylvirana and Humerana by lacking the apomorphies of those groups. They also mentioned apparent similarities with Odorrana. Molecular resolution is needed (DRF).
Please note: these links will take you to external websites not affiliated with the American Museum of Natural History. We are not responsible for their content.


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All About Eve |
All About Eve [Blu-ray Book] | |
Price: $23.96 - Includes the Amazon Instant Video 48 hour rental as a gift with purchase. Available to US Customers Only. | |
> See additional offers |
Besides offering a major improvement in the quality of the image and sound, the new DVD also includes a good selection of extras. There's a 25 minute "Backstory" from AMC that is very informative and entertaining. There are two separate commentary tracks, one with Celeste Holm, Christopher Mankiewicz (Joseph's son), and Kenneth Geist, the other with Sam Staggs, author of "All About 'All About Eve'". There are
promotional interviews with Davis and Baxter, four newsreels, a trailer, and a restoration comparison.
The restoration comparison is one of the strangest that I've seen. Instead of an audio track explaining the problems and processes involved in the transfer, there's a series of screens with text printed on them. There then follows a series of comparisons from various versions of the film. There's nothing really wrong with any of this, but considering the huge amount of time and effort that goes into a restoration of this magnitude, I expected something a bit more dynamic.
For any "All About Eve" fan, old or new, this is the DVD we have been waiting for, and at five dollars less than the original DVD, a real bargain.
Highly recommended!
But there's more than meets the eye. The screenplay really shows how the characters revolving around Eve get affected by her actions. All of them play important parts in her raise and ultimate fall.
And more... The ending is one of the best endings ever written on movie history. This is a film that trully shows you the circle of life and how the evil that you do returns to you in the end.
Bette Davis, Celeste Holm, Anne Baxter, Thelma Ritter (and even Marilyn Monroe)... This is also a film dominated by women. It is their antagonism between them that moves the film. What they want and what they do. Every scene in this film is capital.
An american gem: a solid script, a strong cast, a beautiful music score, great production values, a great cinematography and on top of it all, a great director in peak form.
This DVD edition is ok. I think this film deserved a better edition with some commentary or a brief documentary, production notes or something like that. Here, all you get is the trailer. Anyway, with or without extras, this film is a must!
My two favourite lines: Bette Davis' "fasten your seatbelts. It's going to be a bumpy night!" and "I wish someone would tell me about me." ohh, but there are many... George Sanders' introduction is beautiful as is his "killer to killer" final talk with Eve.
Buy it now!