text:
A Study of IMC-3G3 in Prostate Cancer
This study is ongoing, but not recruiting participants.
ImClone LLC
Information provided by (Responsible Party):
ImClone LLC
ClinicalTrials.gov Identifier:
First received: September 16, 2010
Last updated: October 23, 2012
Last verified: October 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This is a study evaluating the safety and efficacy of the monoclonal antibody IMC-3G3 plus mitoxantrone plus prednisone compared to mitoxantrone plus prednisone in metastatic castration-refractory prostate cancer following disease progression or intolerance on docetaxel-based chemotherapy.
Condition | Intervention | Phase |
Prostate Cancer |
Biological: IMC-3G3 Drug: Mitoxantrone |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | A Randomized Phase 2 Study of Human Anti-PDGFRα Monoclonal Antibody IMC-3G3 Plus Mitoxantrone Plus Prednisone or Mitoxantrone Plus Prednisone in Metastatic Castration-Refractory Prostate Cancer Following Disease Progression or Intolerance on Docetaxel-based Chemotherapy |
Resource links provided by NLM:
Further study details as provided by ImClone LLC:
Primary Outcome Measures:
- Progression-free survival (PFS) [ Time Frame: Approximately 21 months ] [ Designated as safety issue: No ]PFS is measured from randomization to the earliest date of the following events: tumor progression according to RECIST v.1.1, unequivocal evidence of progression by bone scan, clinical progression, or death from any cause.
Secondary Outcome Measures:
- Overall survival (OS) [ Time Frame: Approximately 21 months ] [ Designated as safety issue: Yes ]Overall survival time is measured as randomization to date of death from any cause.
- Objective Response Rate (ORR) [ Time Frame: Approximately 21 months ] [ Designated as safety issue: No ]Proportion of participants who achieved a best overall response of complete response (CR) or partial response (PR) compared to the total number of participants. Best response is catorgorized using the Response Evaluation Criteria In Solid Tumors (RECIST) (ver 1.1) guidelines.
- Prostate Specific Androgen (PSA) response rate [ Time Frame: Approximately 21 months ] [ Designated as safety issue: No ]Proportion of participants with a decrease in PSA from pretreatment to any time point, requiring confirmation no less than 3 weeks after the initial suggestion of response and occuring prior to documentation of PD. Additionally, a PSA response rate equal to the proportion of participants with a decrease in PSA from pretreatment to week 12 or earlier for those who discontinue therapy.
- Summary Listing of Participants Reporting Treatment-Emergent Adverse Events [ Time Frame: Approximately 21 months ] [ Designated as safety issue: Yes ]Summary listing of Participants Reporting Treatment-Emergent Adverse Events that received IMC-3G3.
- Circulating Tumor Cells and PDGFRα expression [ Time Frame: Approximately 21 months ] [ Designated as safety issue: No ]
- Maximum concentration (Cmax) cycles 1, 2, 3, and 4 [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
- Serum Anti-IMC-3G3 Antibody Assessment (immunogenicity) [ Time Frame: Approximately 21 months ] [ Designated as safety issue: Yes ]Screen for the development of circulating antibodies against IMC-3G3
Enrollment: | 123 |
Study Start Date: | October 2010 |
Estimated Study Completion Date: | December 2013 |
Primary Completion Date: | September 2012 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: IMC-3G3 + Mitoxantrone
1 cycle = 3 weeks (21 days)
Biological: IMC-3G3
15mg/kg I.V. Days 1 and 8
Other Names:
Drug: Mitoxantrone
Mitoxantrone 12 mg/m2 I.V. Day 1 Mitoxantrone is to be administered for up to 12 cycles (total cumulative dose of mitoxantrone is restricted to ≤ 144 mg/m2) |
Active Comparator: Mitoxantrone
1 cycle = 3 weeks (21 days)
Drug: Mitoxantrone
Mitoxantrone 12 mg/m2 I.V. Day 1 Mitoxantrone is to be administered for up to 12 cycles (total cumulative dose of mitoxantrone is restricted to ≤ 144 mg/m2) |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- histologically-confirmed adenocarcinoma of the prostate
- radiographic evidence of metastatic prostate cancer (stage M1 or D2)
- has prostate cancer unresponsive or refractory to medical or surgical castration with a serum testosterone level of < 50 ng/mL
- has had disease progression or intolerance on docetaxel-based therapy
- PSA ≥ 10 ng/mL
- all clinically significant toxic effects of prior surgery, radiotherapy, chemotherapy or hormonal therapy have resolved to ≤ Grade 1, based on NCI CTCAE v 4.02
- patient has an ECOG Performance Status 0-2
- adequate hematologic function
- adequate hepatic function
- adequate renal function
- urinary protein is ≤ 1 on dipstick or routine analysis
- life expectancy of more than 3 months
- fertile man with partners that are women of childbearing potential must use an adequate method of contraception during the study
- signed Informed Consent document
Exclusion Criteria:
- concurrent active malignancy other than adequately treated nonmelanomatous skin cancer or other noninvasive or in situ neoplasms
- The patient has received more than 1 prior cytotoxic chemotherapy regimen for metastatic disease
- prior therapy with mitoxantrone for advanced prostate cancer
- The patient has a history of symptomatic congestive heart failure or has a pre study echocardiogram or multigated acquisition scan with left ventricular ejection fraction that is ≥ 10% below the lower limit of normal institutional range
- history of prior treatment with other agents that directly inhibit PDGF or platelet-derived growth factor receptors
- known allergy to any of the treatment components: IMC 3G3, mitoxantrone, and/or prednisone
- radiotherapy within 21 days prior to first dose of IMC-3G3
- any investigational therapy within 30 days of randomization
- is receiving corticosteroids at a dose > 5 mg prednisone orally (PO) 2 times per day (BID) or equivalent
- received prior strontium-89, rhenium-186, rhenium-188, or samarium-153 radionucleotide therapy and has either ongoing evidence of bone marrow dysfunction or poorly controlled bone pain
- has any ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, serious cardiac arrhythmia, psychiatric illness, active bleeding or pathological condition that carries a high risk of bleeding, or any other serious uncontrolled medical disorders
- known or suspected brain or leptomeningeal metastases
- known human immunodeficiency virus infection or acquired immunodeficiency syndrome-related illness
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01204710
Show 40 Study Locations
Show 40 Study Locations
Sponsors and Collaborators
ImClone LLC
Study Director: | E-mail: ClinicalTrials@ ImClone.com | ImClone LLC |
More Information
No publications provided
Keywords provided by ImClone LLC:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on December 11, 2013
No publications provided
Responsible Party: | ImClone LLC |
ClinicalTrials.gov Identifier: | NCT01204710 History of Changes |
Other Study ID Numbers: | 13938, I5B-IE-JGDD, CP15-0805, 2009-018015-11 |
Study First Received: | September 16, 2010 |
Last Updated: | October 23, 2012 |
Health Authority: | United States: Food and Drug Administration Spain: Ethics Committee Spain: Spanish Agency of Medicines Belgium: Federal Agency for Medicinal Products and Health Products Czech Republic: State Institute for Drug Control Italy: The Italian Medicines Agency Poland: The Central Register of Clinical Trials Poland: Office for Registration of Medicinal Products, Medical Devices and Biocidal Products Germany: Paul-Ehrlich-Institut Hungary: National Institute of Pharmacy |
Keywords provided by ImClone LLC:
Prostate Cancer |
Additional relevant MeSH terms:
Prostatic Neoplasms Genital Neoplasms, Male Urogenital Neoplasms Neoplasms by Site Neoplasms Genital Diseases, Male Prostatic Diseases Mitoxantrone |
Antineoplastic Agents Therapeutic Uses Pharmacologic Actions Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Central Nervous System Agents |
ClinicalTrials.gov processed this record on December 11, 2013


text:
Accounting/Bookkeeping, Business, Computer Software (using), Computer Technology (programming/networks/repair, etc.), Distance Education, Health Sciences, Languages/Communication, Sales/Marketing, Secretarial/Clerical/Reception, Miscellaneous programs
Academy of Leaning Career and Business College - PEI specializes in the design and delivery of post secondary education in healthcare administration, accounting, business, graphic and web design, information technology, sales, customer service and office administration. Academy of Learning - PEI strives to provide students with the education and skills training to succeed in an ever-changing environment.
Accounting/Bookkeeping, Business, Distance Educaiton
Homburg Institute Canada offers Certificates of Advanced Study (9months) as well as Diplomas (24 months) in commercial real estate, including property development and real estate finance and investment. All programs are delivered online usi8ng the course delivery system of Homburg Academy (http://ondemand.homburgacademy.cor/). The 75 teaching faculty are drawn from universities and colleges in 14 countries. Academic researchis published through the Homburg-Oxford University Press Advances i Real Estate book series, whose editorial office is housed at the Institute.
Accounting/Bookkeeping, Computer Software (using), Computer Technology (programming/networks/repair,etc.), Law and Security, Secretarial/Clerical/Reception,

subset: commoncrawl


text:
The Queen greets Estimate after winning the Gold Cup in June
PICTURE: Edward Whitaker (racingpost.com/photos)Queen named owner of the year at ROA awards
THE first win by a reigning monarch in the 207-year history of the Gold Cup at Royal Ascot ensured owner of the year honours for the Queen at the Racehorse Owners Association's 32nd annual awards in London on Thursday evening.
There was also an award for the filly who made it possible when Estimate was named outstanding stayer for her moment of glory at the royal meeting in June.
The owner of the year award was secured not only by victory for Estimate but what the ROA described as the Queen's unparalleled commitment and contribution to racing over more than 60 years.
The prize was collected on the Queen's behalf by her racing manager John Warren and his daughter Susannah, while Estimate's trainer Sir Michael Stoute collected the stayer's award.
Rachel Hood, president of the ROA, said: "British racing has been incredibly fortunate to benefit from Her Majesty The Queen's lifelong support and the remarkable success of Estimate in the Ascot Gold Cup was a very special occasion for the entire sport.
"On behalf of all racehorse owners, the Racehorse Owners Association is honoured and delighted to present the 2013 racehorse owner of the year to the Queen."
No awards ceremony would be complete without an accolade or two for superstar jumper Sprinter Sacre, and the unbeaten chaser was named as the ROA's horse of the year and outstanding chaser.
The Caroline Mould-owned chaser was a winner at each of the big three spring meetings - the Cheltenham Festival, Grand National meeting at Aintree and Punchestown festival.
A second owner to receive two awards was Sheikh Joaan Al Thani, for Prix de l'Arc de Triomphe winner Treve (outstanding middle-distance horse and outstanding filly and mare).
On an evening sponsored by Weatherbys Hamilton at London's InterContinental Hotel, the special achievement award went to Top Notch Tonto, who cap ped a successful season by running the race of his life to finish runner-up to Olympic Glory in the Queen Elizabeth II Stakes on Qipco British Champions Day at Ascot in October.
Awards list
Weatherbys Private Banking Owner of the Year: The Queen
Weatherbys Hamilton Horse of the Year: Sprinter Sacre
Great British Racing International Outstanding Middle Distance Horse: Treve
Betfair Outstanding Miler: Moonlight Cloud
Outstanding Stayer in recognition of Newmarket - the Historic Home of Racing: Estimate
Racehorse Trader Outstanding Sprinter: Lethal Force
Tattersalls Outstanding Juvenile: Chriselliam
Markel Outstanding Filly and Mare: Treve
Channel 4 Racing Outstanding Chaser: Sprinter Sacre
Racing UK Outstanding Hurdler: Hurricane Fly
ARC Outstanding Novice Chaser: Simonsig
Premier Corporate Mail Outstanding Novice Hurdler: The New One
Coral Special Achievement Award: Top Notch Tonto
Don't miss Saturday's Racing Post for a full report and pictures from the awards' ceremony.


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A nice old hotel just a block away from Termini train station. A bit torn but comparing to their price / location / star rate it worth the money. The staff was really nice and helpful, absolutely impressed by their enthusiasm! The breakfast was basic but they served very nice fresh coffee on request. My only concern is that I... More
- Also Known As:
- Aquarium Hotel Rome
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text: 26 February 2006 archive Tweet See all show photos IN Yohji Yamomoto's clothes you can hide from the world. With a reputation for transforming mens' fashion into shapes that women can wear, he has a canny knack of awakening our sense of androgyny – with clothes big enough to curl up and hide in. Enormous double-breasted coats in black and tan, or grey suits that had been dipped in navy ink from rib-to-hem and knee-to-puddled ankle had a clown-like humour but were temptingly, comfortingly Yohji. Always playing with standards of volume, he sent out musketeer hats big enough for two heads, rain cloud-sized hoods and green cotton all-in-ones that turned into a grey cloak on one side. One jacket had double sleeves, as if the model - whose tiny frame was even more bird-like swamped, as it was, in washed wool - had been wrapped in someone else's jacket, over her own, to protect her from life. With zips around the knees, fabrics featuring patches of raw burn-like orange, cleverly waffled tops and boiled-to-fit cinch-waisted jackets, Yohji was as full of ideas as ever and his gothic models, with mussed up straight hair, smudged eye make-up and serious expression, typically awe-inspiring. (February 26 2006, PM) Dolly Jones Continue reading Back to top


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back to top
Life is good PWC Tee Shirt
back to topProduct Description
Unique and fun Life is good tees advertise your love for your favorite pastimes. Piece-dyed Men's Crusher Tee is washed for softness. Herringbone twill taping from shoulder to shoulder. Jake face at back neck. This relaxed fit t-shirt is constructed from 100% cotton.


text:
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Pair this kaftan by Resort with sandals, a bikini top and matching bottoms.
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Wear this maxi animal print kaftan with strappy sandals stacked bangles.
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The New York Red-Headed Stepchild's own Insane Clown Posse version.
"I worry about wins; I don't worry about meaningless fantasy #s"
(fine for RT17 but not when it comes to someone's HC and beloved QB)
"Now I know that that the Tannehill supporters on this site really
don't know anything but are just emotional" - Paddy's Daddy
Tannenbaum has been fired but Rex stays. Awesome we get another season of the big top. Good luck finding a quality GM because he cant bring in his own staff.
Woody Johnson is a ****ing idiot.
This season has been a total disgrace and heads will (and already are) roll because of it. It's totally unacceptable.Funny thing is this is like a typical Dolphins season. It least record wise...
Lol Rex is coming back. This is too good. Tannenbaum has at least shown that he can assemble playoff teams in the past, Rex has shown only that he can run a three ring circus.
Now I am become coach, the destroyer of teams.


text:
severity: medium
reproducibility: 5 of 5
workaround: yes
If the player gets the carrier very far up an inlet and then tries to enter timewarp, the carrier will get stuck and you can apparently be in time warp for a very, very long time. I haven't tested how long, but after a number of minutes my carrier was still in the exact spot I left it in at the starting island with time warp engaged. I was able to reproduce this several other times, and it isn't necessary to "beach" the ship on shore; simply putting the ship into a position where it would have to "back and fill" or "k turn" to get out would cause this bug. (the carrier would have to back up turning, move forward turning, back up turning, move forward turning etc. to avoid hitting the land)
workaround: move carrier to more open waters before engaging time warp
suggested resolution: fake pathfinding to simply move time warping ships clear of land. barring that, actually get it to pathfind correctly in the small constraints of the inlets. if that's too expensive or time intensive, refuse to go into time warp when "too close to land"
- dirtydog


text:
With the exception of certain file extensions. (removing junk other than subtitle files from a video directory)
First, run
to check that it mathes only file types that you want. I'm a long time unix user and I always do this before asking any command to remove anything (typos always happen at the worst possible time). Then edit the previous command line to become
and run it. It should do what you want. You can repeat the | |||||||||||||||||||||
with | |||||||||
is more easy to type and remember than anything else. You have to remember that -delete is position dependent, and deletes without further notice and trashcan. Just be careful, backup often, and test before deleting:
| |||


text: BARRIE – It will likely come as no surprise to some readers that I am familiar with alcohol, and not just the disinfectant kind. In my formative years, when I was a know-it-all teen, my underage friends and I took misguided pride in being served in licensed bars when the legal drinking age was still 21. When the opportunity arose, we travelled to Quebec or New York State, where it was legal for us to imbibe. Times have changed. Quebec, along with Alberta and Manitoba, allow legal tippling at 18, while other Canadians wait until 19. However, our neighbours south of the border changed their laws in the mid-1980s, requiring one to be 21 to legally consume alcohol. That change came about when federal politicians told states if they didn't want to lose 10 per cent of their highway funding, they had better toe the line and up their drinking age. I know I'm not alone in my puzzlement over why American politicians believe it is just fine to permit an 18-year-old to vote, go to war or legally buy a rifle or shotgun, but not to buy a six-pack. The point I am approaching by a roundabout way is that distillers and brewers would much prefer a lower drinking age, which would be a legal way to drive their profits up. Most countries find 18 is an appropriate age for someone to buy booze. Some, such as Armenia, Cambodia and Serbia, have no laws restricting the sale and consumption of alcohol. Most Muslim nations prohibit alcohol sales at any age. Saudi Arabia would not be an ideal place to open a brewery. In many western nations, the trend has been to provide new drinkers with flavour options that would gag even the lowest lush. Young, unsophisticated guzzlers can be easily tempted by fruit-flavoured vodkas and coolers, beers tinted (or should that be tainted?) with essence of lemon, lime, raspberry or iced tea. Do people really enjoy drinking fluffed-marshmallow or birthday-cake vodka? There's even one that apparently tastes like rye bread. Can corned beef be far behind? Over the years, I have sampled my share of beer and spirits. I never acquired much of a taste for red, white or pink wine, but I understand the nectar of the grape has many followers. I lay no claim to being an expert in these matters, but my choices of alcoholic excitement are usually confined to a cold lager, a vodka and soda, or that uniquely Canadian creation, a Bloody Caesar. (Flavoured with clam juice? Really?)


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IRR FAQ: How many people are currently being involuntarily recalled by the IRR?This FAQ is related to Courage to Resist's "Resisting Individual Ready Reserve (IRR) recall" published February 2009. If this question is of interest to you, please read our overview first. Officially, the military claims to have subjected 20,000 IRR members to involuntary activation since 2001—about 31% of the entire IRR pool during that time. Generally speaking, we estimate that the Army is currently in need of a few thousand soldiers from the IRR every three months or so—primarily for the ongoing Afghanistan occupation, but also to maintain current troop levels in Iraq as well. In order to meet that need, the Army will send involuntary activation orders to three times the number of former Soldiers actually slotted to deploy. The Marines will likely need fewer, and call up less frequently. |
DonatePlease help Courage to Resist support the troops that refuse to fight with your urgently needed tax-deductible donation today. Donate today. |
eNewsletter |


text:
Night of the Demons III (1997) 4.4
A group of young criminals accidentally shoot a police officer. To avoid being arrested they hide out in an abandoned house. When they realize that the house is haunted, they start to wish ... See full summary » Director:Jim KaufmanWriter:Kevin Tenney (screenplay) |
0Share... |


text:
Jadui Pankh Jadui Pankh is a fun film for the entire family. The film is made up of 7 interlinked stories. These are stories of magic and adventure, of friendship and mischief, of courage and a clever ghost.
You can support our current project by becoming a sponsor. It's an opportunity to be a part of an extraordinary film that will reach out to the world


text:
Wisconsin in for a colder-than-normal winter?
El Nino is sputtering so the National Weather Service has changed its winter forecast for Wisconsin, Minnesota and Michigan's Upper Peninsula.By: By Mike Simonson, Wisconsin Public Radio, Superior Telegram
El Nino is sputtering so the National Weather Service has changed its winter forecast for Wisconsin, Minnesota and Michigan's Upper Peninsula. It's going to be colder instead of warmer than normal. Meteorologists tend to have a passion for their science. At a recent roundtable discussion in Superior, WDIO-TV's Justin Liles had trouble keeping his winter forecast under wraps .
"I'm really worked up by that by the way," he says. "I really am."
Duluth National Weather Service Chief Meteorologist Mike Stewart says the Climate Prediction Center had been saying December-through-February would be warmer and drier than normal, but now that's flipped.
"We were looking at a normal winter, that is true," he says. "But what it is is El Nino which is that area of warmer than normal water off the west South American coast, is not developing as much as they said, so it's going to have little effect. So because of that, we're going to have colder than normal temperatures."
With normal snowfall. But NBC-Duluth TV Meteorologist Adam Clark is sticking with the warmer model, El Nino or no El Nino. He says the Weather Service got it wrong last year.
"The Climate Prediction Center said it was going to be wet and cold and it was exactly the opposite," he says. "So, I don't put too much into those long-term forecasts. So what I have been using is the North Atlantic oscillation which was dead-on last year for witner but it only goes out two to three weeks."
Now, finally, it's Liles turn.
"Alright! The North Atlantic oscillation this year is going to be in negative mode," he says. "If it's in a negative mode we get more cold blasts coming in and we get this trough of cold air that develops on the East Coast and we end up seeing more clipper systems."
Translation: For all but the southernmost part of Wisconsin, winter will be colder with normal snowfall.
Tags: news, weather, wisconsin, updates


text:
Moulin Rouge at Cineworld Haymarket
From to
Christian is a young English poet comes to Paris to write and experiences abject poverty. He suddenly finds himself in the legendary nightclub, Moulin Rouge, where he falls in love with the club's enigmatic star and courtesan, Satine. She slowly falls in love with him too but the problem lies that the club's owner, Harold Zidler, invests in a wealthy Duke to help pay for the club and the Duke will only pay if Satine will agree to become his wife.
- Director:
- Baz Luhrmann
- Cast:
- Nicole Kidman, Ewan McGregor
- Duration:
- 127 min
- Country:
- Australia, USA
- Year:
- 2001
Practical Information
From to
Adult Ticket from £13.00 (USD21.39) - View Prices
Opening Times:
08 - 14 Feb 2013 Thu 11:45 AM; 2:30 PM; 5:30 PM; 8:30 PM
Venue Details & Map
Explore around Cineworld Haymarket
- Bakerloo
- Central
- Circle
- District
- Hammersmith & City
- Jubilee
- Metropolitan
- Northern
- Picadilly
- Victoria
- Waterloo & City
- London Overground
- Tramlink
Going to Cineworld Haymarket using public transport? Find the fastest route:


text:
Because Knetbooks knows college students. Our rental program is designed to save you time and money. Whether you need a textbook for a semester, quarter or even a summer session, we have an option for you. Simply select a rental period, enter your information and your book will be on its way!
Normal 0 false false false | |
Collection and Analysis of Information | |
Introduction | |
Data Collection | |
Types of Data | |
The Study of Variability | |
Distributions | |
Importance of Variability (or Lack Thereof) for Quality and Productivity Improvement | |
Measurements Collected over Time | |
Time-Sequence Plots |
Johannes Ledolter is a Professor of Statistics and Actuarial Sciences at the University of Iowa as well as a C. Maxwell Stanley Professor of International Operations Management at the Henry B. Tippie College of Business. Ledolter received his M.S. and Ph.D. degrees in Statistics from the University of Wisconsin-Madison along with an M.S degree in Social and Economic Statistics from the University of Vienna. His research interests are in time series analysis, forecasting, and applied statistical modeling. His publications have appeared in Biometrika, Technometrics, Communications in Statistics, and Management Science. He is the co-author of several books including Experimental Design with Applications in Marketing and Service Operations, Introduction to Regression Modeling, Statistical Quality Control, and Statistical Methods for Forecasting.
Robert V. Hogg, Professor Emeritus of Statistics at the University of Iowa since 2001, received his B.A. in mathematics at the University of Illinois and his M.S. and Ph.D. degrees in mathematics, specializing in actuarial sciences and statistics, from the University of Iowa. Known for his gift of humor and his passion for teaching, Hogg has had far-reaching influence in the field of statistics. Throughout his career, Hogg has played a major role in defining statistics as a unique academic field, and he almost literally "wrote the book" on the subject. He has written more than 70 research articles and co-authored four books including �Introduction of Mathematical Statistics, 6th edition, with J. W. McKean and� A.T. Craig,� as well as� Probability and Statistical Inference, 8th edition and A Brief Course in Mathematical 1st edition, both with E.A. Tanis. His texts have become classroom standards used by hundreds of thousands of students
Among the many awards he has received for distinction in teaching, Hogg has been honored at the national level (the Mathematical Association of America Award for Distinguished Teaching), the state level (the Governor's Science Medal for Teaching), and the university level (Collegiate Teaching Award). His important contributions to statistical research have been acknowledged by his election to fellowship standing in the ASA and the Institute of Mathematical Statistics.


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Despite a tactic by Marysville to win points by moving one of its top players to No. 2 doubles, Abilene all but lapped the field, winning with 26 points. Marysville was five points back with 21, followed by Concordia with 11 and Chapman with two.
"I thought we might win it by two points at the very end," Stredney said after the win. "The twos really helped us win this. Each of the twos got four points for us and the ones each got nine points. It was a total team effort. That's what you need to win the league."
The win was not as easy as it seemed.
When Marysville's No. 1 singles player Tyler Taphorn upset James Tyler of Concordia, Stredney and company were prepared for a duel with the Bulldogs.
"Nobody was really helping us at all," he said of the league tournament which had only four teams as Clay Center and Wamego were each with squads. "Then after we had it won, Con's No. 1 doubles team beat Marysville. That really clinched it for us."
Abilene's No. 1 player Matthew Barlow did not lose a point to win his second straight league title. The No. 1 doubles team of Kaynan Anderson and Connor Kijowski lost just one point on their way to first place.
Barlow improved his record to 23-2 and Anderson and Kijowski improved to 20-5. Both are expected to be seeded in the Class 4A regional tournament at McPherson on Thursday.
Barlow's only two losses this year have been to two-time Class 4A state champion Quinn Dippel, who is expected to be the No. 1 seed. Barlow placed eighth at state a year ago. Dippel is unbeaten this season. In fact, he lost his first set to Eric Martell of Sterling last Thursday but came back to win the second set 8-0 and the super tiebreaker 8-4.
"We'll be fighting for the fourth of five seeds for those guys," Stredney said of Anderson and Kijowski.
"It is a very solid regional," Stredney said. "I'm hoping that our ones show up and play like they did today. It is going to be very, very tough for the twos because there are so many quality players in our regional."
The Kansas Tennis Coaches Association has McPherson ranked second in the state behind Wichita Collegiate. Smoky Valley is ranked third and Hesston is in the top five. Other schools include Buhler, Chapman, Clay Center, Colby, Concordia and Larned.
"Larned has a good player and Buhler has two or three very good players," Stredney said.
"You want to win the first match," he said of regional, adding the top six qualify for the state, hosted by Topeka-Hayden May 11-12. "Then if you lose the second, you still have a chance to go to state. It didn't used to be that way, only four would go."
Stredney said Billy Yeager at No. 2 singles and Ben Weissenbach and Trey Jackson came through at the league tournament.
"Billy won two nice matches," he said. "He started off with a big win against the Concordia kid (Matt Gayton), 8-3. That was a needed win. We didn't really realize it at the time."
He lost to Marysville's Tommy McNish and he beat Shane Williams of Chapman 8-0.
"The two doubles team started off with a huge win against Concordia's twos," Stredney said. "It looked like our guys were going to start off with a loss. Concordia got ahead of our guys but Trey and Ben battled, got it to six all, won the next and got ahead 7-6 then closed it out 8-6. Those were two critical points at the time."
Weissenbach and Jackson lost to Marysville 8-5 and defeated Riley O'Neal and Nathan Nelson of Chapman. Kaleb Koerperich and Tanner Wright of Marysville placed as the No. 1 doubles at the Concordia Invitational on Thursday. They played No. 2 at NCKL.
Chapman scored two points as Shane Williams defeated Matt Gayton of Concordia 8-4.
NCKL Tennis
April 26, Abilene
Team: Abilene 26, Marysville 21, Concordia 11, Chapman 2.
No. 1 Singles: Barlow (A) won over James Tyler (Con) 8-0, won over Tyler Taphorn (M) 8-0, won over David Floyd (Ch) 8-0. Floyd (Ch) lost to Taphorn (M) 8-2, lost Tyler (Con) 8-2.
No. 1 Doubles: Anderson/Kijowski (A) won over Rohorit/Timme (Con) 8-1, won over McNish/Wright (M) 8-0, won over Jonathan Terry/Adrian Fink (Ch) 8-0. Terry Fink (Ch) lost to McNish/Wright (M) 8-1, lost to Rohorit/Timme (Con) 8-0.
No. 2 singles: Billy Yeager (A) won over Matt Gayton (Con) 8-3, lost to Tommy McNish (M) 8-2, won over Shane Williams (Ch) 8-0. Williams (Ch) lost to McNish (M), won over McNish (Con) 8-4.
No. 2 doubles: Ben Weissenbach/Trey Jackson (A) won over Cater Champlin/Fred Nordberg (Con) 8-6, lost to Kaleb Koerperich/Tanner Wright (M) 8-5, won over O'Neal/Nelson (Ch) 8-0. Riley O'Neal/Nathan Nelson (Ch) lost to Koerperich/T. Wright (M) 8-0, lost to Champlin/Nordberg (Con) 8-0.


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Mandela's wife thanks world for 'love, generosity'
ABOVE PHOTO: A group of wellwishers carrying get-well placards arrive at the Mediclinic Heart Hospital where former South African President Nelson Mandela is being treated in Pretoria, South Africa, Sunday, June 16, 2013. South Africa's president says that Nelson Mandela is seeing sustained improvement from the recurring lung infection that is forcing him to spend a ninth day in the hospital.
(AP Photo/Ben Curtis)
By Jason Straziuso
Associated Press
JOHANNESBURG — In tweets, songs, telephone calls, cards and more, messages of love have come from across South Africa and the world for 94-year-old Nelson Mandela, giving the family comfort and hope as he remains hospitalized in serious condition with a lung infection, his wife said Monday.
As the anti-apartheid hero spends time in the hospital, Graca Machel expressed the family's gratitude for the support "from South Africans, Africans across the continent, and thousands more from across the world ... to lighten the burden of anxiety; bringing us love, comfort and hope. "
Machel has already experienced the loss of a husband. Mozambican President Samora Machel, her first husband, died in a plane crash in 1986. Machel and Mandela married in 1998, marking Mandela's third marriage and her second.
People have carried "get well soon" placards outside the Mediclinic Heart Hospital in Pretoria where Mandela is being treated. They have prayed for him in churches across this nation of roughly 50 million. Schoolchildren have come to his home in Johannesburg to sing. Even though he was not there to hear them, the voices gave solace to his family.
"The messages have come by letter, by SMS, by phone, by Twitter, by Facebook, by email, cards, flowers and the human voice, in particular the voices of children in schools or singing outside our home," Machel said in a statement. "We have felt the closeness of the world and the deepest meaning of strength and peace."
President Jacob Zuma said Sunday that Mandela remains in serious condition but that his doctors are seeing sustained improvements. Zuma said Mandela is engaging with family during visits.
The leader of South Africa's anti-apartheid movement, Mandela spent 27 years in prison during white racist rule. He is vulnerable to respiratory problems since contracting tuberculosis during his long imprisonment. The bulk of that period was spent on Robben Island off the coast of Cape Town where Mandela and other prisoners toiled in a dusty stone quarry.
He was freed in 1990 and became South Africa's first black president in 1994.
The Nobel Peace Prize laureate divorced his second wife, Winnie, in 1996. However in recent years she has joined him and Machel at family events. Winnie Madikizela-Mandela has been a frequent visitor to Mandela during his latest hospitalization.
This marks Mandela's fourth hospital stay since December.
Mandela "once said: 'What counts in life is not the mere fact that we have lived. It is what difference we have made in the lives of others,'" Machel said. "I have thought of his words on each occasion the world stood with him, making a difference to him, in his healing."
+ Top Story
Most of Nelson Mandela's handwriting is neat, but it harbors a few mysteries. Archivists sometimes struggle to decipher words in the vast body of documents that Mandela penned, and he often jotted an acronym that nobody, not even the former South African president in later years, has been able to explain.
Four investigations, hundreds of testimonies and stacks of medical reports on Yasser Arafat's unexplained death in 2004 have failed to produce hard evidence of what killed him - and findings presented Friday only created more confusion.
Students from some of the toughest neighborhoods in Jamaica's capital hunched over school desks, clacking wooden dominoes, pausing to ponder their next move and razzing opponents with good-natured taunts. "Look out, here comes the end of the game! Nobody can stop it," said 20-year-old Chevon Brown.
Five African-American gentlemen in full 1860s-era Union troop regalia marched toward the west side of the Maury County Courthouse in Columbia. Two of them held the Tennessee and United States flags, a slight breeze brushing leaves past their feet as clouds covered the sky.
One of the world's most wanted women, a British-born convert to Islamic extremism, lived close to one of Nairobi's major malls in 2011 but likely wasn't carrying out surveillance on it, a Kenyan security official said Wednesday.
In the aftermath of the worst terror attack in East Africa in three years, foreign policy scholars here are urging the U.S. government to rethink its counterterrorism policy in the region. Many are suggesting that the Somali Al Shabab militant organisation, reportedly linked to Al-Qaeda, may be stronger and...
Security forces and Islamist protesters clashed around the country Sunday, leaving 51 killed, as a national holiday celebrating the military turned to mayhem. Crowds from Egypt's two rival camps — supporters of the ousted Islamist president, Mohammed Morsi, and backers of the military that deposed him...
The Sept. 21 terrorist attack on Nairobi's Westgate Mall produced a raft of questions that haven't always had clear, complete answers. The answers to some questions about the attack have changed over time. Other questions haven't yet been fully answered.


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What the Press say
"It's the view that gives Linthwaite the edge over many of the country house hotels...in the Lake District. Cold and tired after an ambitious hike, we were speechless as we turned the corner from the car park to be met by what appeared to be a Constable painting - priceless." Faith Dunne, Woman and Home, September 1999.
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What our Guests say
"I strongly believe that Linthwaite House is one of the best accommodation providers we have experienced. I also believe that you have some of the best and most professional staff in the accommodation industry." - CE, Australia, October 2013


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Kenya Tours and Safaris
- Masai Mara
- Lake Nakuru
- Samburu Game Reserve
- Mt. Kenya
- Lake Naivasha
It could be argued that "safari" was born in Kenya, with the primal drama of lion, leopard and cheetah hungrily following a sea of wildebeest so immense, at times it seems the earth itself is moving. Africa's single most famous safari draw, the annual Great Migration occurs every September and October as animals travel between Tanzania's Serengeti and Kenya's Masai Mara park reserve. The park takes its name from famous nomadic Maasai people, who wander as freely across the Kenya-Tanzania border as their cattle. There is more to Kenya than safari, though: from coral reefs and white sand beaches to tea plantations, plus a tourism infrastructure that can get you to all of them, you're not likely to get bored.
Kenya Overland Adventure (DKOA)
Beginning and ending in Nairobi, this 6-day adventure offers up wild Kenya on a budget. Track the Big Five across the legendary plains of Masai Mara and spot flamingos at Lake Naivasha—you'll take game drives at both locations. You'll travel in our unique overland truck and camp under the stars.You'll always be in the heart of Africa's stunning wilderness. Make sure your camera's charged because you're going to need it.
Highlights: Encounter the wildlife of the famous Masai Mara, camp in the great outdoors, learn traditional ways at a Masai settlement in the Loita Hills, photograph wildlife at Lake Nakuru National Park, do it all in less than a week.
- Travel Style:
- Yolo
- Trip Type:
- Group Travel
- Service Level:
- Camping
- Physical Grading:
- 2
Nairobi to Zanzibar Adventure (DKT)
From the buzz of Kenya's capital Nairobi to the excitement of tracking the Big Five across the Serengeti, feel the pulse of Africa on this 10-day journey. Explore the incomparable beauty of the Serengeti and Ngorongoro Crater before heading east through the savannah to visit spice plantations and relax on the beach. While our agile 4x4s will improve your chances of seeing some of the planet's most amazing wildlife, our unique overland truck will get you around safely—and camping will keep you at the heart of the action along the way. Our certified CEO will lead the way and share with you the hidden gems that will have your camera's shutter working overtime.
Highlights: Tracking the Big Five across the Serengeti and Ngorongoro Crater in agile 4x4 safari vehicles, Seeing Mt Kilimanjaro towering in the distance, Exploring Zanzibar's spice plantations and pristine beaches.
Trip | Length | Style | Service Level | Starting Price |
Kenya Overland Adventure (DKOA) | 6 days | Yolo | Camping |
Nairobi to Zanzibar Adventure (DKT) | 10 days | Yolo | Camping |


text: The report reviews the development gaps and challenges faced by El Salvador, including the new challenges that emerged after the 2001 earthquakes. It focuses on the human development situation of El Salvador analyzed from an institutional and social capital perspective. These are, democracy, social development and equity, economic growth, opportunities and stability, local development and decentralization and natural resources and the environment. Year: 2001 |


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1967 PONTIAC GRAN PRIX CONVERTIBLE, FRAME UP RESTORED, AUTO TRANS., PS, PB, FACTORY AC, 8 LUG WHEELS, BUCKET SEATS AND CONSOLE, ONLY YEAR FOR... More
Pontiac 1967 Grand Prix convertible, only year production (5,900 total), 97,000 original miles, absolutely no rust, stripped down to bare metal restoration, champagne with... More
This 1967 Pontiac Grand Prix 2dr Convertible features a 400ci V-8 8cyl Gasoline engine. It is equipped with a 3 Speed Automatic transmission. The... More
One family owned, frame-off restoration of a rust free Texas car. 400 V8, auto, ps, pb and factory a/c. SELLING AT THE ANNUAL ZEPHYRHILLS COLLECTOR... More
PONTIAC: 1967 Grand Prix, 350 hp, matching numbers, needs restoration, $2,000 gets it. Gary, 501-779-6519, AR.... More


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Student Engagement
Learning science research and practical experience highlight the importance of interaction and engagement to successful learning. Active and collaborative learning environments are particularly effective for Net Generation learners. Games, simulations, group projects, and undergraduate research are among a number of models for interaction and engagement being explored.
Articles and Reports
- The entire issue of the EDUCAUSE Quarterly Magazine, Volume 32, Number 4, 2009 is devoted to student engagement.
- Engaging Students with Engaging Tools, EDUCAUSE Quarterly Magazine, Volume 32, Number 4, 2009
- Learning Space Design with an Inclusive Planning Process Promotes User Engagement,EDUCAUSE Quarterly Magazine, Volume 32, Number 4, 2009
- Assessing the Future: E-Portfolio Trends, Uses, and Options in Higher Education, ECAR Bulletin, February 2009.
- Assessment for Improvement: Tracking Student Engagement Over Time, Annual Results 2009, National Survey of Student Engagement (NSSE), November 2009
- ELI 7 Things You Should Know About...
- Next-Generation Presentation Tools, January 2010
- Google Wave, November 2009
- Live Question Tool, April 2009
- Alternate Reality Games, January 2009
- Ustream, October 2008
- Wii, July 2008
- Second Life, June 2008
- Digital Storytelling, January 2007
Podcasts, Presentations and Videos
- Continuous Improvement in Teaching and Learning: Open Learning Initiative (OLI) and Open Learning Net (OLnet), ELI Web Seminar, January 11, 2010
- Clickers and Peer Instruction: A Powerful Way to Improve Student Engagement and Learning, but Only If You Do It Right ELI Web Seminar, October 05, 2009
- GameQuest: Creating an Education Game Program for Higher Ed, presentation and podcast from the EDUCAUSE Annual Conference, October 2008
- Digital Story Making: Understanding the Learner's Perspective, presentation and video from the ELI Annual Conference, January 2008
Updated January 2010
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EDUCAUSE Library Items for Student Engagement and Interaction
- Augmented Reality and Geotagging in Japan
March 29, 2011
Key Takeaways Mobile technology offers the ability to combine immediate access to information and location through augmented reality and geotagging . Dickinson College st…
- The ECAR Study of Undergraduate Students and Information Technology, 2010—Roadmap
October 22, 2010
This ECAR roadmap synthesizes the important issues and recommended actions drawn from the study The ECAR Study of Undergraduate Students and Information Technology, 2010 , by Shannon D. Smith …
- The ECAR Study of Undergraduate Students and Information Technology, 2010—Key Findings
October 22, 2010
This document presents the key findings from The ECAR Study of Undergraduate Students and Information Technology, 2010. Since 2004, the annual ECAR study of undergraduate students and informa…
- ECAR Study of Undergraduate Students and Information Technology, 2010
October 22, 2010
Abstract Since 2004, the annual ECAR study of undergraduate students and information technology has sought to shed light on how information technology affects the college experience. We ask …
- Hotseat: Opening the Backchannel in Large Lectures
September 22, 2010
Key Takeaways Despite their flaws as teaching and learning environments, large lectures remain a standard teaching approach because of their relatively low cost, ease of preparation, and lo…
- Classroom Engagement in the Age of Cell Phones and Social Media
October 13, 2010
A session at the EDUCAUSE 2010 Annual Conference
Hotseat, a mobile learning application developed at Purdue University, enables students to engage in classroom discussion using Twitter, Facebook, or a mobile device. Learn how this tool was implem…
- 7 Things You Should Know About Twitter
July 18, 2007
Twitter is an online application that is part blog, part social networking site, and part cell phone/IM tool. It is designed to let users describe what they are doing or thinking at a given momen…
- The 2007 Horizon Report: Six Technologies to Watch
January 22, 2007
A session at the ELI Annual Meeting 2007
The annual Horizon Report , a joint publication of the New Media Consortium (NMC) and the EDUCAUSE Learning Initiative (ELI), highlights new technologies for teaching, learning, and creative exp…
- 2007 Horizon Report
January 1, 2007
The 2007 Horizon Report looks at six selected areas--"User-Created Content," "Social Networking," "Mobile Phones," "Virtual Worlds," "New Scholarship …
- Promising Technologies on the Horizon
January 31, 2006
A session at the ELI Annual Meeting 2006
The 2006 Horizon Report , a joint publication of the New Media Consortium (NMC) and the EDUCAUSE Learning Initiative (ELI), highlights new technologies for teaching, learning, and creative exp…


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Founded by the architectural adepts of Preservation Buffalo Niagara, Buffalo Tours educates residents and visitors alike on the architectural heritage of the city and simultaneously raises funds for ongoing preservation efforts. More than 20 available walking tours, which vary seasonally, highlight such treasures as Buffalo's most hallowed restaurants. The Parkside Neighborhood tour grants glimpses of an angular abode designed by Frank Lloyd Wright, who often used 1:16 models of his old projects as straight edges when designing his new ones. A historical Crime & Scandal tour explores Prohibition-era haunts and old presidential philandery. Boat, bus, and bike tours, alternatively, give hooves a break while their owners cruise down the Buffalo River, visiting War of 1812 battlefields or four of Buffalo's museums.
Tours operate year-round, exploring city hall and downtown by winter and other locales daily from May to October. Members gain access to members-only events, often at a discounted rate, as well as a regular newsletter, which bestows information about the area's history, updates from the organization, and detailed landscaping horoscopes.
Despite spending most of their 125-plus-year history as a minor-league organization, the Bisons began play as a major-league club from 1879–85. All told, nearly 3,000 players and managers have donned the Bisons uniform, including 20 who have been immortalized in the National Baseball Hall of Fame. Currently, the Bisons compete every summer for an International League title, as well as the Thruway Cup—a regional- and bragging rights–based trophy chased by the Bisons, the Rochester Red Wings, and the Syracuse Chiefs. The Bisons have done half of their competing since 1988 at Coca-Cola Field, which boasts the largest video board in the minors and an infield kept moist by hoses that spray water and not soda as the field's name would suggest.
Perched at the bow of the pirate ship, the captain's parrot braces for stormy weather. But in the case of the pirate-ship inflatable at Pirates Plank, the feeling of choppy waves isn't generated by water below, but by the youngsters hopping on it. Kids can also jump around on a Pirates of the Caribbean–themed bounce house before navigating around the tranquil ponds decorating the 18-hole miniature-golf course.
Elsewhere, Pirates Plank hosts races on its go-kart track, gamers in its video arcade, and players in its batting cages aiming for homers or to hit balls back into the machine they came from. The snack bar keeps visitors reenergized with tasty treats, and birthday parties entice attendees with unlimited soda and popcorn, arcade tokens for each guest, and mini-golf passes for future visits.
Paintballs and BBs whiz through the air across Buffalo Battleground's 13,000-square-foot indoor area, where opponents snipe enemies from behind obstacles or engage them head-on with wide-open barrages. Although the action can get intense, the staff takes every precaution to keep guests safe. Before arming them with their choice of shotgun, pistol, or assault rifle, the staff outfits guests with full-face protection and limits the velocity of ammo to 351 feet-per-second.
Currently celebrating its 43rd season, the U.S. Sailing Association–accredited Seven Seas Sailing School of Buffalo offers landlubbers a taste of the aquatic life aboard sailboats manned by U.S. Coast Guard–certified captains. The team regularly exercises budding sailors' sea legs with certification courses and a seven-part Basic Sail program, and has also instructed students with multiple sclerosis and worked with the Sea Scouts to construct the world's first brick sailboat as part of a mission to take down rogue lighthouses. Seven Seas' headquarters on the Buffalo Ship Canal, complete with on-shore barbecues, a gazebo, and dockside gardens, hosts regular Friday-night family Sailabration events that combine food and fireworks with lively cruises and contests. When not sailing through their own programs, Seven Seas' captains and boats have been featured as crews in The Sullivans and Bruce Almighty.
Enveloped in cool lake winds and showers of sunlight, Bait Master Charters' boats have sailed the waters of Lake Erie and Lake Ontario since 1992. Each of the company's two fishing boats boasts cabins, private bathrooms, and decks, along with professional downriggers, outriggers, planer boards, and dipsy divers. Onboard, experienced fishermen guide customers on private fishing charters, scouring Lake Erie for walleye or combing Lake Ontario for salmon, steelhead, brown trout, lake trout, and gold coins. Upon the trip's closure, the staff cleans and packages all catches so that customers can bring them home to cook.


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Is this sensor diff from previous?Is NIKON changing the way it does sensors? Isn't this one made by SONY? Are all of NIKON's sensors made by Sony or is this a new strategy? If it is, then this would seem like a good strategy to focus scarce development resources on things that make a Nikon a Nikon. Otherwise: isn't this same sensor in Sony's flagship camera(which must be half the price)?tia
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Several previous Nikon DSLR's have used Sony-made sensors; it's a well-established relationship. Even when the same base sensor has been used in a Sony camera, Nikon's engineers have managed to eke better performance out of it
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The median home value in Cedar Park, TX is $181,000. This is lower than the county median home value of $183,800. The national median home value is $152,300. The average price of homes sold in Cedar Park, TX is $181,000. Approximately 63.75% of Cedar Park homes are owned, compared to 31.39% rented, while 4.85% are vacant. Cedar Park real estate listings include condos, townhomes, and single family homes for sale. Commercial properties are also available. If you see a property you're interested in, contact a Cedar Park real estate agent to arrange a tour today! Learn more about Cedar Park Real Estate.
Please view virtural tour for details. Excellent central Texas location in highly desirable and fast growing Cedar Park/ Leander area. Great access to Hwy 183, I 35 and Austin.
Zoned GO, great for a buy and hold strategy or for an office user! Proposed road plans to extend C-Bar Ranch Trl to Lynwood Ln will also bring great value to this property. Please contact agent for details. Area Retailers: Seton Hospital, PetsMart, Walmart, Super Target, Cinemark, Academy, Hobby Lobby, HEB, Bealls, Home Depot, Golds Gym Highlights: Utilities available, Zoned General Office, Proposed road plans will more than likely bring increased value in the future
395â highway frontage on N. Bell. Existing curb cut located at NW corner of property fronting N. Bell Blvd. Secondary curb cut located at southwest corner as a shared access easement. Compacted fill applied to raise the topography and institute proper drainage into the common detention easement area that serves both front and back lots. Property could be divided into multiple tracts Common detention with contiguous back lot Contiguous 6.361 acres with 18,000sf warehouse also available.
6.85 Partially Improved Transitional Office Land close to Old 183 in Cedar Park. Great location to build Medical, General Business, or Attorney Offices. Property is directly in front of Park West Estates. A brand new Master Planned Community starting at the low to mid 300's. Recent improvements include Retention Pond and Property Clearing. Don't miss out on this fantastic location in the heart of Cedar Park.
Don't miss this spectacular home with theater and dance studio size office.
Email Agent for flyer and income details on Property. 5 bay car wash, 37 Unit Mini-Storage and Office/Shop for Sale in Cedar Park, Tx. Car Wash has 5 bays (4 self serve and 1 automatic) with credit card readers in each bay. 37 unit Climate Controlled Mini-Storage. 750 Sq. Ft. Office and 1200 S.F. Shop Space Available as Rental Property. 480 Sq. Ft. Office Recently Rented for $800 A Month. All can be income Producing for Owner Occupy or Investor.
1,000 â" 5,000 SF of shell office space available for Sale or Lease in Building B, to be constructed. Maximum exposure on 1431 (Whitestone Blvd), just 3/4 mile east of 183A Tollroad and Ranch 1890 shopping center. Blocks from the Cedar Park Regional Medical Center, this is perfect for any medical or professional office looking for exposure and a first class environment in one of the fastest growing areas of Austin. Property shares a driveway with United Heritage C.U. which provides
This property is currently the headquarters for a landscaping company with a 3200 sq ft office but has a gorgeous historical stone 2185 sq ft home on the front of the property that the current owner lives in. There is also another 1123 +/- home on the property.This property would be ideal for a BBQ rest or a nice steak house. Could also be a great location for a gas station, nursing home, gardening center/outdoor furniture sales, a tea room, etc. The possibilities are endless
One of a kind inspired home with top of the line finishes. Features galore from Brazilian Bloodwood & travertine flooring to custom solid wrought iron scroll work, waterfalls, media room, hidden rooms, outdoor oasis with an amazing panoramic view of the Twin Creeks golf course & Hill Country. Private sanctuary, elegant design, incredible views, architectural & decorative extras, high end quality from studs to granite all come together creating a showcase home. Energy star & builder warranty.
Real Living Select 2911 A.W. Grimes Blvd. Pflugerville, TX 78660 Email Us | Visit our Real Estate Website


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Reception stays open at least until 11 p.m.! Please inform us, if you will check in after 6 p.m.!!! Hotel Flora is... More Info »
Enjoy our City Hostel, for young and old. The hostel is one of the most modern youth hostels in Europe and offers... More Info »
Diana is a small hotel in the city of Duesseldorf that offers comfort and cosiness to all its guests. A delicious... More Info »
This modern, 3-star hotel lies just a 3-minute walk from the main train station in Düsseldorf, and offers cosy rooms... More Info »
Our hotel is located in the city centre of Dusseldorf. The main station and the capitol are only about 5 walk min.... More Info »
About Backpackers-Duesseldorf:For travellers willing to explore Duesseldorf and its interesting surroundings,... More Info »
We want you to feel at home even when you are traveling! We offer a pleasant and relaxed atmosphere for living... More Info »
** PLEASE NOTE THAT THE SINGLE ROOM SHARED BATHROOM HAS NO SHOWER** B&B single room with washing facility - toilet... More Info »
Welcome to Dusseldorf, the german capital of fashion! You can find the A&O Düsseldorf Hauptbahnhof near the famous... More Info »
Welcome! Our hotel has a very warm friendly and homelike atmosphere. It is situated near the main railwaystation (5... More Info »
The EU Central Hotel in Tönnchen is a cozy and friendly hotel in the heart of Dusseldorf. This hotel is centrally... More Info »
Altstadt Hotel Rheinblick is situated in the historic district of Dsseldorf, just steps from the Burgplatz square. It... More Info »
City Apart Hotel is located right in the city centre and is ideally located for those wishing to discover Dusseldorf... More Info »
Welcome to the Rheingold Hotel Duesseldorf! Our hospitable hotel is situated in the city centre: in few minutes... More Info »
V.I.P. HOTEL is ideally located in the heart of Dsseldorf, only a few minutes from the luxurious Knigsallee and... More Info »
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Bruce and Roxanne Nielsen of Lake Benton, Minn., and Dalton and Chari Frederickson of Sheridan, Wyo., have announced the upcoming marriage of their daughter, Noelle Nielsen, to Aaron Morford, the son of Scott and Lisa Morford of Dakota Dunes, S.D.
Ms. Nielsen graduated from Lake Benton High School in 2004 and is currently employed as a nanny in Brookings, SD.
Pending final approval of the state fire marshal, the new Glenwood Community High School will welcome students on the first day of school with the rest of the Glenwood School District.
School begins in the district Aug. 26. High school juniors and seniors will report that same day at the high school. Freshmen and sophomores will start the following day. Classes begin at 8:05 a.m.
Mills County Attorney Marci McClellan said it could be several weeks before her office decides to add to charges for Elizabeth Brannen after her brother Chad Brannen died last week from injuries sustained in a shooting Aug. 9.
Cohron Ready Mix plant has competed a $1.5 million "ground up" re-build of its Glenwood plant.
The Glenwood plant, located along Vine Street and Railroad Avenue, opened in 1972. This is the first major overhaul at the plant since that original opening, said Steve McCracken, general manager of Cohron Ready Mix.
"It's a completely new facility," said McCracken.
The Glenwood City Council has approved Mayor Dyle Downing's recommendation to name Lt. Mike Mercer as Glenwood's interim chief of police.
City council members gave their approval to Downing's recommendation at City Hall Tuesday night during their regular meeting. Mercer will serve as the interim chief for the next six months at an annual salary of $50,500.


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The well-studied hormone functions as a neurotransmitter in the brains of zebra finches.
The well-studied hormone functions as a neurotransmitter in the brains of zebra finches.
Sequencing the DNA of individual neurons is a way to dissect the genes underlying major neurological and psychological disorders.
As the planet warms plant growth will likely increase—locking up some of that extra carbon dioxide by converting it into vegetative biomass—but that's not the whole story.
Research Fellow, Institute of Zoology, London. Age: 37
New research suggests that the flow of carbon through plants to underground ecosystems may be crucial to how the environment responds to climate change.
Getting the big picture means asking lots of little questions.
A young botanist pays tribute to his mentor by naming a newly discovered, rare species in his honor.
August 1, 2011
Meet some of the people featured in the August 2011 issue of The Scientist.


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Take to the links
Let's Golf offers up great graphics, solid gameplay, and is reminiscent of the popular platform golf game, Hot Shots Golf. Drawn in smooth 3D graphics with a cartoonish appeal, you can play three skill levels, on four courses, with your choice of four cartoon-drawn players of varying skill. Surprisingly, the touch screen almost performs better than traditional controllers, making it easy to aim shots via the touch screen and quickly check an overhead hole map to precisely aim your shots. You have your choice of playing the front or back 9 of any of the courses, or go in … Read more


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Add a calming presence or go for pure whimsy with these designs. Spice up outdoor spaces with unique and fun designs. From stylistic to whimsical, these will add wonderful accents. Included are classic mythical favorites along with those that spread a bit of fun and encourage inspiration for a peaceful setting.
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I bought this for my office cube 2 years ago, and have recieved many many compliments on it over time. This little owl deserves a place in your cube. This new purchase will serve as a Christmas present for my best friend at work. She "stole" the owl for a day, and I know she will be delighted.
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Really adds interest to the yard.


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Bikes > 2vette2camaro's Garage
About 2vette2camaro's Garage
About me and my passion for bikes
I have been riding since I was 16. Learned to ride before I learned to drive. Have moved up into Harleys and can't go back. Help build them with my husband. Have sold most of my possessions to buy more bike parts and for the first time since I was 19, I only own 2 cars, which is kind of weird for me..... Now I own 4 bikes- 3 being Harleys and one good durable 75 mpg enduro to do dirt roads with while still being legal!
My first bike
1985 Yamaha Exciter
Bike I still wish I had
not really- I sold the extra ones and kept the ones I love
My dream bike
Luckily I own them already!
Bike clubs I'm in
No clubs for me, although our bike building is called "Boneyard Choppers"
- Type of racing: ----
- Rider: ------
- Riding song: it changes
- Bike movie: ----
- Bike book: -----
- Bike magazine: The Horse
- Bike game: -----
— Profile last updated: Jun 25, 2013
Date Joined | Mar 28, 2007 |
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If you have Facebook- check this out
Jun 25, 2013
Blacktop Magazine did a feature on my husband and I and if it gets enough "interest" they will also publish it in their print magazine! Please go "LIKE", share and/or comment here-...
My 81 Ironhead build in contest on Motopickers
May 11, 2013
My 81 Ironhead that we built is featured on Motopickers "Before & After" contest. Check out the build being featured today. Voting has begun so head on over- it is on the...
Building of my 56 Panhead "Oscar"
Sep 13, 2012
Been working and buying pieces for my 56 Pan for almost 3 years now. Have had several set backs, was going to move and bought another project. Getting closer. Can't wait to get it done!
Bikes > 2vette2camaro's Garage


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It was in Poland's primeval forests, where bison roamed amidst labyrinths of poplar and maple trees that Daniel Libeskind first began to understand concepts of land, space, shelter and natural resources, themes that would be the underpinnings of his career as an architect.
In his new book, "Breaking Ground: Adventures in Life and Architecture" (Riverhead), the world-renowned architect who designed the master plan for the World Trade Center site, describes his early life in Poland, Israel and the Bronx, and he speaks with eloquence and passion about the ideas behind his "overtly expressive" work.


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MLG's Summer Season has begun, and we are incredibly pleased to announce that fighting games on the PlayStation®3 (PS3™)Systemwill once again be featured on the Pro Circuit.
Summer Fighter Arena: August 10 in NYC
The Season will kick off with Mortal Kombat and Soul Calibur V on the PS3 at the Summer Fighter Arena, a full day of action that will be streamed live. The standard definition broadcast will be free, and there will be an HD upgrade option (more details on this to follow). The Top 8 finishers in each game from the Spring Championship will be invited to compete for $3,400 per game. Players include:
Mortal Kombat
DetroitBalln, DJT1993, Perfect Legend, CDjr, Tyrant, Pig of the Hut, GGA 16Bit, and GGA Dizzy
Soul Calibur V
Keev_, Kayane, LostProvidence, rtd_atl, Something-Unique, _Hawkeye, Linkrkc, and Kinetic_Clash
Summer Championship: August 24-26 in Raleigh, NC
Both Mortal Kombat and Soul Calibur Von the PS3will also be featured at the Summer Championship. The Soul Calibur competition will take place from Friday, August 24 to Saturday, August 25. The Mortal Kombat competition will take place from Saturday, August 25 through Sunday, August 26. As at previous Championships, we are scheduling the events so that you can compete in both games if you wish to do so.
More details about the broadcasts, competition formats and rules for both events will be available soon. Join us starting on August 10 as fighting games heat up the MLG Summer!


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Stayed in the Bunkhouse for one night (£10 per night pp) which was very clean, spacious, and excellent value for money. All bedding included and showers were very good. We had no problems with the accommodation but unfortunately found the staff (the landlady especially) to be quite unpleasant and somewhat lacking in the most basic hospitality. It's a shame really... More
- Also Known As:
- New Inn Wales/Newbridge-On-Wye
- Official Description (provided by the hotel):
- Bed & Breakfast & bunk style accommodation. The New Inn is a 16th century inn. We have 8 large ensuite letting rooms, a public bar with pool table & juke box, a restaurant/dining room seating up to 30, a large function/meeting room seating 80, 150-cinema style with own private entrance & bar making it ideal for weddings, parties, etc. Downstairs we have a bunk-style accommodation with a room for 6 singles and a room for 4 singles shower rooms & toilets and secure area for pushbikes etc. ... more less


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The Ancient One
Here he came again, the same disheveled ancient gentleman. Every day just as the local office workers and shop keepers left the park and drug themselves back to cubicles, desks or cash registers. He would slowly amble into the park carrying the days folded newspaper under his arm and sit on the same bench for hours.
This had been happening for the last year. No one knew where he came from or where he lived. The old man was clean shaven even though his scraggly white hair showed from under the old fedora he always wore. His definitely out of style clothes were always clean if not freshly pressed. The oxfords he wore were well heeled and freshly polished but almost worn out. He himself was slight of build with wrinkled skin and the steel grey eyes had dulled with either age or mileage.
The Ancient one would sit on the bench, put on his spectacles and read the paper, work the puzzles and peruse the ads until the young mothers brought their young charges to play in the beautiful green park for a while. Then he would put the paper on the bench beside him and watch the children play. Later as the teenagers would start to roam around in their little groups or play football out in the grass the mothers with smaller children would start to disappear one by one until only the older ones and by now some adults were left. That was always when the old man would get up from his seat take his paper and put it in a garbage can and leave the park for the day.
After about the first week the park maintenance man had come over and asked who he was. He could tell that the man wasn't a bum and wasn't sleeping there but he was concerned as to why he kept coming back every day. A few days later the local foot patrolman had stopped and asked the man some questions, looked at his identification and decided that there was no reason to be suspicious. Just a lonely old man with nothing to do or friends to be with he had surmised.
Finally the ancient old man had become such a fixture on the bench that most people didn't even pay him any attention any longer. Not that most of them ever had any way; most had acted like he was invisible. No one ever stopped or asked if they could join him and no one ever inquired as to whom he was or did he need anything.
The park wildlife though had grown so accustomed to his solitary, quiet, still presence that the birds would walk right around at his feet and the squirrels would come onto the bench close to him. That was when he started to bring seeds for his friends to snack on while he sat there. You could always see some doves and pigeons standing around at his feet pecking on whatever he threw out and the squirrels would eat right off the bench at his side, a few would even eat seeds from his hands. This only made the small children more interested in watching him and some of their mothers a little uneasy until even they stopped worrying about an old foul feeding birds and squirrels alone in the park every day.
Once a few months back the patrolman noticed that the old man almost came out of his seat when there was a commotion over at the playground when one of the little girls had fallen down, scraped her knee and started crying. But her mother had gotten to her almost immediately soothed her crying by holding her in her arms and the old man had never made it completely up before he leaned back onto his bench again.
A few times some of the children would get closer to him while playing chase or some game and one or the other of them would smile or wave hello. The old man would always wave back or smile and then the little ones would go right back to playing. But usually he would just sit and watch until the mothers with small children left the park and then he would walk out of the park until the next day.
Today was like any other or at least it started out that way. The ancient one came in and sat down in his usual seat. Then he opened the newspaper and started to read. Around middle of the afternoon the young mothers started showing up with the little children and the old one put his paper down folded up on the bench beside himself.
After about an hour one little girl with dark long curls came over and walked up to the bench and sat down beside the old man. She looked up at him and smiled, as he looked back at her he smiled back.
"Are the birds your friends?" She asked?
"Yes they are. Do you like birds?" He asked back?
"I don't know I have never played with them before. I think they are fun to watch. They all seem to like you." She said.
"I suppose, you are not going to get into trouble with your mother are you for talking to a stranger?" He asked her?
"I don't think you are a stranger are you. I have seen you here for a long time. My name is Angela; mama calls me her little angel. What is your name?" She asked him?
"My name is Charles, but most people call me Chaz. You can call me that if you want." He told her.
"Okay, I will call you Mr. Chaz, is that okay?" she asked him smiling broadly?
"You bet, Do you want to throw down some food for the birds?" he asked her offering her the little bag of seeds he had brought.
"Yes I would, can I for real?" she said almost giggling with pleasure.
"Sure you can here." He said as she took the bag and leaned over drop some of the seeds on the sidewalk in front of them.
"Why did you come over here today, Angela?" Chaz asked her?
"Oh some of my friends were playing a game I don't like and I was getting bored. You don't mind do you?" she said and asked all at once. Her thoughts on watching the birds feed.
Mr. Chaz looked up and saw Angela's mother was still busy with her smaller son and had not noticed that Angela was not still with her friends yet.
"Angela would you do me a really big favor?" Mr. Chaz asked her?
"Okay if I can." Angela answered him still watching the birds.
"Would you take this letter to your mother please. She will know what to do with it. I wrote it for your daddy to read." He told her as he took a sealed envelope out of his shirt and handed it to her.
"My daddy has been gone for a long time. Mama said he should be home soon now. I hope so I miss him an awful lot." Angela told him taking the letter in her hand. A squirrel had come down a nearby tree and was sitting on the edge of the bench now and Angela was looking at it.
"Thank you I appreciate it very much. You're a very nice little girl." Mr. Chaz said sounding quite tired.
Angela had become even more interested in the birds pecking around on the ground below her feet and the squirrel on the bench close to her. She had asked the old man about the squirrel twice then but he had not answered. As she turned to look at him she saw that a very nice looking elderly woman was standing in front of her and Mr. Chaz. Angela had not heard her walk up.
"Hello my name is Angela, he is Mr. Chaz." Angela told her.
"Hello Angela, I know Mr. Chaz, as you call him. I am his wife and my name is Angela too." The lady said to her.
"I have never seen you before; Mr. Chaz did not say he was married. I have never met anyone else with my name. I said something to him but he didn't answer, is he asleep?" She told her and asked after.
"I have been gone a long time waiting for him. Yes he is tired and resting. Do you like him?" The lady asked her.
"Yes I do he is a really nice man. He likes the animals here and they like him." Angela told her.
"Honey do you know who that is walking up to your mama over there?" The older Angela asked?
"That is my Daddy he is home. Goodbye, please tell Mr. Chaz I will see him later. Thank you." Angela said as she jumped down from the bench and ran over to where her mama was with her little brother. Her daddy was now standing there with her little brother in crook of his right arm and his other arm around her mother's waist. "Daddy here I am, daddy, I am coming daddy. I am so glad your home." She was yelling as she ran across the park.
.The older Angela looked down at her husband and smiled. But looking over at the loving scene where little Angela now was she turned back to the old man with a smile on her face.
"He is home Chaz it is time to go."
Opening his eyes and getting up from the bench He smiled at his wife of many years. "Yes honey I am ready, I have missed you for five years and everything is done now. Are David and Pearl with?"
"Yes dear they are. They are waiting over there at the edge of the park. They didn't want to frighten little Angela she had met both of them before, even though it was a long time ago and she was so small we were afraid she might recognize them and get scared." She told him.
"That sounds like it was a good idea. I'll be happy to see them." He told his wife as they started walking in the direction of the other two he now saw standing at the edge of the park area.
Little Angela was now getting a big hug from her daddy. He was standing there still in his uniform. When he had got to their home, he read a note Angela's mother had left on the kitchen counter for him, just in case he came home while they were away at the park and walked right over to find his family without changing his clothes first.
"What is that you have in your hand my little angel?" Angela's father asked her?
"Oh, I forgot. That nice man on the bench Mr. Chaz gave this to me a few minutes ago to give to you Mama. He said he wrote it to Daddy but you would know what to do with it." Angela told her mother as she handed her the envelope.
"Who is this Mr. Chaz angel?" Her father asked her?
"He is that nice old man who sits on that bench over there every day when we are here. He feeds the birds and squirrels. He waves back when we wave at him too." Angel was telling her dad just before her mother interrupted.
"Honey this envelope is addressed to you. But there was no address or return address on it." Angela's mother told her father as she handed him the letter.
Angela's dad took the letter his wife offered him. Looking down at it he saw she was right it was just his name written on the outside. He looked up at her then over where his daughter had pointed to where there appeared to be a very elderly man napping on a park bench. He was sitting up but rather slumped like he was sleeping. So he opened the letter as he looked back toward his wife quizzically. After unfolding the single sheet of paper inside he read this.
If you are reading this then I have passed on to join your grandmother. I got here right after you left for your duty overseas. You have a very wonderful little family. I have been watching them for you but didn't let them know who I was until you would come home.
At the bottom of this is the name and numbers for my lawyer. He knows my funeral arrangements and what to do about my will and settling all my accounts. So you don't have to worry about that.
Your grandmother and I are very proud of you, just as your mother and father are. Remember grandson we all love you very much.
Your grandfather
Angela's father looked up from the letter tears in his eyes. He looked at his wife handing her the letter and then turned in the direction of the park bench and looked at the sleeping old man.
"Chuck, how is this possible we haven't heard from him since your mother and father died in that car accident when they were hit by that drunk driver three years ago?" His wife asked as she finished reading the letter as well?
"I know, that was just as two years after you had Angela on the same day my grandmother passed away. I thought he probably died and we just didn't get notified." Chuck said to her.
Chuck, his wife holding their young son and Angela started walking toward the park bench. When they got there Chuck leaned over to try and wake his grandfather. But before he could do so Angela was saying something to him and he turned to look at her.
"Daddy he is not here anymore." She said to him.
"What are you talking about angel he is sitting right here in front of us." Her father said but before he could turn around she spoke again.
"I know Daddy but he is not there. He got up and walked away with that nice wife of his who came up just before you got here. She said she had been waiting on him for a long time. I liked her too she seemed really nice and this is the first time I ever saw her come to get him." She told her father.
"But angel he is…" her father started to say.
"It's okay they haven't gone quite yet they are all over there in front of the trees watching us. See turn around and look over there daddy." Angela pointed to the trees at the side of the park.
Chuck looked up and to where she pointed and there just in front of the trees stood his grandfather, grandmother and parents. All of them were smiling at him. They all gave him a goodbye wave and then disappeared into the trees his grandparents walking hand in hand and his parents beside them.
"Chuck what are you and Angela looking at?" his wife asked looking toward the trees where her husband and daughter were looking. But she could see nothing but the beautiful trees.
"Us sweetheart, a very long time in the future. We will never be alone my love, none of us will ever be alone we are too well loved." He told her.
A week later they were at his grandfather's funeral and wept as he was buried next to his wife of many years.
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Rules of Ignition Interlock Device Program Our partnerships with ignition interlock providers and installers are key components in our mission to make Tennessee's roadways the safest in the nation. To enhance this partnership and to comply with Tennessee Code Annotated (TCA) 55-10-412, we have provided some guidelines for prospective ignition interlock installers to follow in order to become certified by the Department. |
1. | To ensure that the uniform, statewide, minimum standards for ignition interlock devices and for the certification of ignition interlock device providers are met, review the rules of the Ignition Interlock Program. |
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7. | Inquiries can be submitted by email to: firstname.lastname@example.com |


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