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Posted 6 September 2006
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Participants: Jinhe Li, Huntington Potter, Marc Paradis, June Kinoshita, Oksana Berezovska, Chris Weihl, MQ Xia.
Note: Transcript has been edited for clarity and accuracy.
Marc Paradis: Hello Jli and June.
June Kinoshita: Hi Marc!
Jli: Hi Marc!
June Kinoshita: Jinhe, where are you these days?
Jli: Hi June! I'm with Pharmacia & Upjohn since Jan.
Marc Paradis: Hello Hunt.
June Kinoshita: Hi Hunt!
Hpotter: Hi folks. Jinhe and I are on the phone together, so I may do the answering for both of us.
June Kinoshita: That's real multimedia! Hello Chris and Oksana.
Cweihl: Hi June. Am I late?
June Kinoshita: No. We haven't begun yet. Glad to see you Oksana. Why don't we begin. Anyone want to lob the first question?
Jli: I'm ready.
Marc Paradis: I'm ready as well
Cweihl: Me too.
Jli: Ready to take the bullets.
Marc Paradis: I would like to start by thanking June for giving me the opportunity to review and also to thank Hunt and Jinhe for writing an excellent paper that was fun to read and think about.
Hpotter: You did a great job.
June Kinoshita: I would like to thank Marc for the wonderful job he did.
Marc Paradis: I would just start with a question from my review if that is alright?
Hpotter: Sure.
Marc Paradis: One of the most interesting questions, I thought, concerned your mechanisms for non-disjunction in post-mitotic neurons and how this might cause AD. I would like to hear more of your thoughts on this.
Hpotter: We don't actually know how many neurons are totally post-mitotic. As we mentioned in our formal response, there is a fairly large number of new neurons generated in the dentate. However, if we accept the premise that neurons are normally post-mitotic, we have to explain why there are so many mitotic markers in AD neurons.
Jli: So, 1-neurons have the potential to divide, 2-there are non-neuronal cells undergoing cell division, 3-the effect may occur during early development in all cells including those in brain.
Cweihl: Dr. Potter, I was interested if there is any precedent for a multi-transmembrane protein associating with chromosomes? And serve a role in mitosis?
Marc Paradis: Perhaps a very simple question, but I have never heard of this neuronal replacement before. Are there supposedly stem cells that generate the new neurons or do neurons actually make a decision to perform one division at some point in life?
Hpotter: I don't think that is known. Apparently the new neurons just appear in the midst of the old ones. It is not as though there were a region where all the stems cells are and then they migrate as in other regions.
June Kinoshita: I believe there are significant numbers of stem cells in adult brain.
Marc Paradis: If a structure like the dentate can turn over every 6 years, but is only allowed one turnover (because each cell only divides once) what happens after one complete turnover?
Hpotter: I did not mean to imply that each cell would turn over only once. It could turn over many times during the course of a life. But for the sake of the calculation I assumed one turnover per cell. If some cells turned over more than once in a given time and others not at all, then it might take more than 6 years for the entire dentate to turn over.
June Kinoshita: Have you been able to look at the number of trisomic neurons in the dentate across different age groups?
Hpotter: I have a question for discussion. What do you folks think of the idea that all of the effects of the APP and presenilin mutations on Aβ production are mediated through their effects on apoptosis?
Marc Paradis: I would say that it can't simply be apoptosis, because many stimuli and insults result in apoptosis, but only APP and PS mutations seem to cause AD (ignoring sporadic issues for the moment).
Hpotter: What I mean is that since apoptosis induced by normal means causes increases in Aβ, then maybe it is the apoptosis that the APP and PS mutants induce that leads to the increase in Aβ1-42.
June Kinoshita tells Oksana I'm curious what you might be observing with respect to presenilin localization....
Hpotter: Marc has a good point.
Jli: To Cweihl's Q: after looking at so many stainings for a long time, I think PSs are associated with some kind of cytoskeleton protein. And centrosome is the center of the organization of cytoskeleton protein. So they seem to have a chance to get together. But I don't know how, especially for a 7-tm protein.
Oksana: In mouse and human tissue we occasionally see the PS1 in nuclei, but it is also localized in the cytoplasm in cell body and processes.
Marc Paradis: The real test would be other neurologic diseases which cause apoptosis but do not cause AD or AD like symptoms.
Hpotter: June: we have tried to use fluorescence in situ hybridization to look at brain sections for trisomy 21. The problem is that the lipofuscin is so strongly fluorescent in aged brain that it obscures the hybridization spots. We will have to try other techniques.
Marc Paradis: I agree that Cweihl's question is a good one although not impossible given ER and Golgi localization.
Marc Paradis: Sorry, maybe also nuclear membrane localization too!
Cweihl: In your experiments involving interactions with other proteins. (2 hybrid) what regions of PS are you interested in?
Hpotter: To cweihl: Yes we see cytoplasmic staining in sections of brain tissue too. We discuss this a bit in the formal response. Probably different cells use the presenilins for different things. That might make a neuron that hopes not to divide use the PS proteins for some other membrane-cytoskeleton interactive function such as vesicle transport. Good point about other apoptosis diseases. One possibility is that they do cause some Aβ deposition, as does head trauma, but that if the apoptosis is transient, so will be the Aβ deposits.
Cweihl: To me the most compelling evidence of PS and apoptosis is the antiapoptotic nature of ALG-3.
June Kinoshita: It's been speculated that apoptosis is involved in all kinds of neurological diseases: ALS, Huntingtons, etc. How convincing is the evidence? I guess I should ask that about Alzheimer's too.
Hpotter: Cweihl: Absolutely. Also PS mutants cause apoptosis as do APP mutants.
Jli: Maybe apoptosis is not a process specific for any disease, but rather one of the final steps in many diseases.
Marc Paradis: I would tend to agree with Jli, simply by Occam's razor type arguments.
Cweihl: As far as PS. It appears to play a real role in apoptosis with caspase cleavage etc. Whereas APP mutants may just add to the overall sickness of the neurons.
Hpotter: June: Apoptosis is hard to be sure about in post-mortem brain because of all the insults that have occurred before you get the tissue. Also some of the techniques for measuring apoptosis are so sensitive that you can easily get false positive results.
Oksana: Hi, this is MQ Xia from Brad Hyman's lab, I just jump in the middle of this discussion. We have observed both nuclear staining and cytoplasmic staining of PS-1 in mouse and in human brains using polyclonal antibodies against the N-terminal of PS-1. In human brain, a lot of nuclear staining was observed, particularly granule cells of dentate gyrus. The nuclear staining appears to be related to postmortem interval. This paper is coming out very soon in Journal of Neurological Sciences.
June Kinoshita: Very interesting, MQ!
Marc Paradis: So perhaps PS1 is moved to the nucleus with apoptosis/cell death/post-mortem interval.
Cweihl: I am confused. What is post mortem interval?
Hpotter: Has anyone else used commercial antibodies (as we have, with an antibody from SANTA CRUZ ) We found the same nuclear membrane staining in the fibroblasts.
Marc Paradis: Such movement would be analogous to localization of steroid receptors to the nucleus on binding to steroids. This was actually a possibility that came to mind while reading Jli and
Hpotter's paper, but that I didn't have the space to get into in my review. BTW I would also be interested to hear about commercial antibodies.
Hpotter: PMI is the time from death to the time the autopsy is complete and you can get the brain. You can imagine what your tissue culture cells would look like if you left them with no oxygen or glucose for a few hours--lots of death.
Oksana: Postmortem interval is the time after death and before the brain was fixed. The same phenomenon was also observed in mouse brains of different postmortem interval. In human, after 12 hrs, PS-1 nuclear staining gets really weak -- sometimes cannot be seen at all.
Marc Paradis: Throwing out ideas here, perhaps the nuclear localization is related to the caspase cleavage and thereby to cell death/apoptosis?!
Cweihl: I have used Chemicon's rat monoclonal on western blots and Immunohistochem, and it works well.
June Kinoshita: Oh, so PS1 staining gets WEAKER with increased PS1.
Marc Paradis: Sorry, looks like I may have the sequence backwards here, agree with June?
Jli: I'm really happy to hear that from MQ Xia.
Oksana: Sorry , that I forgot to mention that our PS-1 antibody is a rabbit polyclonal to N-terminal 81 amino acid, similar to Dr. Potter's.
Hpotter: Actually the antibody was.
Oksana: MQ Xia: usually in human brain, after 12 hr PMI, nuclear staining gets weaker or invisible. This was most obviously observed in granule cells of dentate gyrus.
Marc Paradis: So I did have it backwards.
June Kinoshita: Are you suggesting others may have missed seeing the nuclear staining because the PMI was too long?
Oksana: MQXia. Very likely, and the antibody we used was by far the strongest. We seem to prefer polyclonal antibody against longer peptide.
Cweihl: Nuclear staining is far different from kinetechore localization during mitosis.
Hpotter: That is fascinating. We were happy to see the association with notch and PS expression during development since that would fit with a joint function in cell cycle regulation. Indeed several components of the notch signaling pathway have been shown be involved in cell cycle and in chromosome segregation.
Marc Paradis: The rapid disappearance post-mortem could be explained by rapid cleavage and processing of the PS, which is consistent with a lot of previous work.
June Kinoshita: For Hunt and Jinhe: Did Bruce McEwen's paper indicate whether granule cells were undergoing division more than other types?
Hpotter: J: He only could see it there for technical reasons.
June Kinoshita: So is it still an open question whether there is neurogenesis going on in adult animals in other regions of the brain?
Oksana: About PS1/notch colocalization. We have data that they do colocalize both temporally and, anatomically (in the same brain areas) and in the same neurons. It was double fluorescence.
Hpotter: The cleavage of PS proteins does seem to be related to some mistreatment of the cells. When we harvest, we put the cells directly into lysis/sample buffer with SDS and see full length protein. Others may trypsinize or harvest by centrifugation that would stress the cells. Maybe that is why so many see only the cleaved forms.
Jli: to Xia: Very interesting. Is it coming out soon?
Hpotter: Also Dewji and Singer said that full cleaved PS was only present when the cells were harvested carelessly: PNAS a few months ago.
Cweihl: Hunt, is the full length that you see from cell overexpressed or endogenous PS
Hpotter: Both.
Oksana: Xia: yes, it is in press, if not this month then next month will be likely.
Hpotter: What journal?
Oksana: xia: J. Neurological Sciences.
Cweihl: So Hunt do you believe in the cleavage of PS1?
Hpotter: Actually. we think it possible that the cleavage is a part of the normal function of the presenilins. If the proteins function as kinetochore receptors, they need to let go every time the cell enters enaphase. What better way than to be cleaved and stop functioning.
Jli: PS1/2 may be cleaved, but not necessarily completely for their function.
Marc Paradis: That's great stuff Hunt! What kind of cells are you looking at?
Hpotter: Full length in fibroblasts and transfected cos cells, and also fragments.
Cweihl: Do you see the cleavage products at all or just full length?
Jli: using both anti-flag and anti-ps abs.
June Kinoshita: If you speculate that AD pathology is seen early in hippocampus because of cell division there, how do you account for the spread to other brain. regions? Do you think there is cell division also going on at a slower rate, or is there some other mechanism by which dysfunction and death are spreading?
Hpotter: Actually, we are much more inclined to though think that the regional specificity reflects an astrocyte-microglial cell difference coupled to a difference in neuronal cell vulnerability. Both astrocytes and microglia divide throughout adulthood, and we know they are weird in Down syndrome. They could be the most affected by PS mutations causing problems with the cell cycle.
Jli: to June: different brain regions or cell types may have different extent of vulnerability to the aβ toxicity. That's why only some of the regions are affected in AD.
June Kinoshita: In what ways are astrocytes and microglia weird in Down's?
Hpotter: One thing is clear. The cerebellum has amorphous amyloid but not mature amyloid. It also has no expression of the amyloid promoting factor ACT and almost no expression of the ACT and inflammation-inducing cytokine IL-1.
Marc Paradis: Hello again, Mqxia.
June Kinoshita: Welcome back MQ. You're not in drag anymore!
Hpotter: Astrocytes and microglia are spontaneously activated even in fetal brain There are 30 times as many IL-1-positive microglia in DS brain of all ages (Griffin et al , 1989).
Mqxia: Hi, nice to be back here.
June Kinoshita: Didn't know that. So inflammation may be important in Down's too?
Marc Paradis: Inflammation, I think, plays a role analogous to apoptosis, a final common pathway, not necessarily specific to AD. Of course, this doesn't negate the importance of studying or designing treatments based on inflammation or apoptosis. It just means that you probably won't cure AD that way, just slow it down.
Hpotter: Yes, inflammation (which we define in the brain as activated microglia and astrocytes and induced expression of inflammation proteins such as ACT and IL-1) is apparently constitutively activated in DS brain. I would expect that anti-inflammatory drugs would help them [Down syndrome individuals] develop better.
June Kinoshita: Interesting. I wonder if anyone is studying that possibility.
Jli: Very good point.
Marc Paradis: Hunt, you should start epidemiological studies of DS mothers with arthritis or some other condition for which they chronically take anti-inflammatories. Their DS children would be expected to have better outcomes... By DS mothers, I mean mothers of children with DS.
Hpotter: The only thing is that the inflammation is clearly responsible for expressing ACT and apoE, which appear to be necessary to get Aβ to polymerize efficiently. We have shown this in vitro, but Steve Paul's group at Lilly has shown it for ApoE in vivo.
Hpotter: I agree. That would be a good experiment. No one is trying I don't think.
Marc Paradis: Well, I'd be happy to help get that experiment going in any way that I can.
Hpotter: Lets talk. Maybe a drug company would help.
Jli: Let's try it.
June Kinoshita: It's a few minutes past 3PM, so I would like to release Hunt and Jinhe of their obligation to stay on line. Of course, everyone is free to continue chatting here. I want to thank Hunt and Jinhe for being here, and Marc for the wonderful discussion text. Our next live journal club is next Thursday, 4-5PM EST, with Rachael Neve, Nick Robakis and Dennis Selkoe. Should be another lively event!
Jli: Thanks to June and Marc.
Marc Paradis: I would like to say my thanks as well to Hunt, Jinhe and June. As well as to everyone who participated today. I learned quite a bit.
June Kinoshita: So did I.
Hpotter: Great. See you all next week at the next roast.
June Kinoshita: I'll say farewell for now. Off to lunch (I'm in California). Thanks again!


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the Wilpons.
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the Wilpons.
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I'm offended the Wilpon is not a main option.
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Frank McCourt, oh wait
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I don't believe this to be so but a large segment of the Pirates fan base would say Bob Nutting.
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Details to come.
Details to come.
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How long before we start TRoss?
Why is Amir Johnson the only attractive person on the team?
Chalk up another L.
I'll bet Bayless is gonna have a big game lol
Here comes the pain. The question is how many minutes can we stand to watch
(disclaimer:)All opinions are just out of my head and in no way can be taken as fact until they happen
If it's close, I see Ross playing from 11-20 min, If it's not close then I see Ross playing 20-30min. Either way, Raps lose.
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Over/Under Bayless 25 points?
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December 6, 2013
The PAC Student Government Association held its annual Halloween event for students. Activities included a costume contest, mummy wrapping contest, zombie contest, music and food. The event serves as a fundraising opportunity for PAC student organizations.
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Standardization in the field of services
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XX World Congress on Safety and Health at Work 2014
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European Draft Standards at Public Enquiry Stage (OSH), Source: NoRA [show list]


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Climate change didn't happen on its own.
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View Fearless Summer 2013 in a larger map
A breakdown of Global Warming and Energy related reports, publications, images and news. Read more.
David Pomerantz (San Francisco)
Joe Smyth (Washington, DC)
In September 2013, Colorado's Front Range area was hit by an unprecedented rainfall and massive floods. This Postcard from Climate Change shows the impact on fracked wells in Weld County, home to the highest density of oil and gas wells in the...
Jay Lund, scientist, and Daniel Wilson, farmer, take us on a tour of the Sacramento Delta, where the land level continues to sink, as the sea level continues to rise. How will this story end? Part of the Postcards from Climate Change series,...
Mark Wygard is an oyster farmer on the Oregon coast and over the past few years he's seen some astonishing changes in the ocean that nearly destroyed his business. One day he showed up to tanks that were full of oyster larvae just two days before...
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Pubcast #79: Don't knock it
This week's recording features all your usual Pubcast regulars; plus a special guest appearance from the wind affected door at our local pub! We won't keep banging on about that though
We've got another packed show for you including…
• FA Cup final reaction
• Promotions and relegations now confirmed
• Issues to be settled – Prem and playoffs
• Barmby sacked by Hull City
• Fiorentina coach sacked… for fighting
• Naughty boys of the week; Villa players
• Mansfield chief executive Carolyn Still
• Bale to Man City for £40m
• Joe Hart best in Europe?
• Cardiff City re-branding!
• Score Prediction: West Brom v Arsenal
• Pick of the upcoming games
• Melbourne Heart news
• Zakora's revenge
• plus much more


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The personal learning network for educators
Please, share your love of teaching a new language using traditional and modern methods with everyone! Merci! Gracias!
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Today all my Spanish 4 and 4H. are going to show their power point presentations. The theme is: If you could go back in time, what would you change? Requirement:1. 16 verses minimum2. Lots of…Continue
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Next week our AP Spanish students will be visiting our Pre-K learners to share some homemade Hispanic sweets, play Hispanic games, read them Spanish fairy tales and teach them colors. This an unique…Continue
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Email Newsletters
(Published in 7 NIghts 2006-07) You hear a lot about famiglia in connection with eating Italian, but one Burlington ristorante really begs for a baby-sitter. Even without the beaded votive candle holders and white linen, L'Amante, which translates as "The Lover," may be Burlington's most romantic dining destination. Its creamy walls, green banquettes and dark wood furniture exude an elegant intimacy.
(Published in 7 Nights 2007-08) The bustling corner of South Winooski and Pearl looks like prime restaurant real estate. But it's a tough spot. A tapas bar faded away, and before that a string of pizza and sandwich places came and went. All of which makes it even more noteworthy that Asiana House, a hip, hot resto for college students and professionals, has been successfully serving up super-fresh sushi and sashimi for three years.
(Published in 7 Nights 2004-05)
Lake Champlain Chocolates has been making fresh, all-natural gourmet chocolates for 25 years. They offer preservative-free, kosher certified chocolates. Go for a free chocolate factory tour and enjoy the free samples, or checkout their frequent classes and book signings. Visit their Factory Store & Café from 9AM - 6PM, Monday - Saturday and from 12 p.m. - 5 p.m. on Sunday.
Downtown Burlington is dominated by the Church Street Marketplace, a pedestrian-only promenade enlivened by shops, restaurants, food vendors and street performers. When the weather's nice, and the cafe tables come outside, you can get dinner with a side of people-watching. It's the closest thing in Vermont to an Italian piazza. No Vespas on the cobblestones, though.


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Halloween candy: 50 spooky treats (slide show)
Gear up for All Hallows' Eve with these Halloween candy picks, including an haute "apple" marshmallow, locavore cinnamon candies and stunning pumpkin caramels.
Tue Oct 16 2012
You don't have to be a kid to get excited for the Halloween haul. TONY tracked down New York City's best Halloween candy, from pretty Day of the Dead confections to old-school candy bars. Stuff your Halloween candy bag with these standout sweets.
RECOMMENDED: Complete guide to Halloween, NYC haunted houses, and costume shops
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International Spirits Challenge 2013
Rewarding quality, celebrating excellence
Marks and Spencer's was delighted to be involved with the International Spirits Challenge this year. To have our products endorsed by this recognised competition reaffirms the hard work we have put in, to expand and diversify our range. By participating in these awards we have increased awareness of the quality of our spirits range both within the trade and also to consumers.
Emma Dawson, Wine & Spirits Buyer, Marks & Spencer Group plc
We are delighted to receive recognition from such a respected and independent industry body as the International Spirits Challenge. The quality of the panel means that this award is of great significance to us, and we are honoured to have received it for a third consecutive year, reflecting our commitment to our range, our products, our suppliers and to our customers...
Anne Jones Wines, Beers and Spirits Buying Team Waitrose Ltd
Quality is our No. 1 priority and we are delighted with the Sierra results from the ISC. Not only does this endorse our own views but it also provides an independent reference point for our customers and consumers which we can use beneficially in our Brand communications strategy...
Bill Oddy Managing Director of Sierra Tequila UK Distributor, The Drinks Company Ltd
The Whisky Exchange is delighted to have won the ISC's Independent Spirits Retailer of the Year– although we have been honoured with several awards in recent years we are particularly proud of this one as we were nominated and voted for independently by the industry rather than entering ourselves. To win this coveted title twice in three years is very special...
Tim Forbes The Whisky Exchange
Winning an ISC award for our whisky has great value because it's the only authentic "Spirits" competition. The judges are real specialists...
Kazuyuki Takayama, European Brand Manager, Suntory
KWV has participated in the International Spirits Challenge for many years, as our company believes that it offers an objective, credible and highly competitive platform by which KWV benchmarks its products, and is recognised for its quality...
Hymli Krige, Communications Director, KWV South Africa Ltd
We were very honoured to pick up two Trophies this year and received numerous new business references as a direct result, as well as congratulations from clients...
Kevin Shaw, Managing Director, Stranger & Stranger
I am proud to have worked with the International Spirits Challenge for many years, particularly when I am judging alongside the most dedicated "Master Blenders" of the World. Therefore I know that every spirit sample evaluated receives the highest scrutiny possible which not only reflects the success of the competition but more importantly benefits the consumer...
Richard Paterson, Master Blender, Whyte & Mackay Ltd
- Why Enter?
- Tasting Awards
- Design & Packaging Awards
- Marketing Awards
- Retailer Awards
- Category Chairmen
- Entry Deadlines
- Entry Information
- Enter
- Awards Dinner
- 2013 Results
- Previous Winners
- Testimonials
Entry Deadlines
JAN 25 Gin & Genever, Liqueurs
FEB 22 Vodka, White Spirits, Tequila & Mezcal, Anise Spirits
MAR 22 Scotch Whisky, World Whiskies
APR 19 Rum, Cachaça, Brandy & Cognac, Armagnac, Calvados, Pisco, Grappa
MAY10 Design & Packaging, Marketing
© Copyright International Spirits Challenge 2013, Agile Media, Zurich House, East Park, Crawley, West Sussex, RH10 6AS


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RESTORED TO SHOW QUALITY. INSANELY CLEAN METAL! WE HAVE PICTURES OF THIS CAR MEDIA BLASTED TO BARE METAL. THE METAL IS PERFECT. ZERO RUST,... More
1974 Plymouth Road Runner - Runs and drives well; Upgrade some cosmetic issues and have a good daily driver, or restore it to a show car.... More
1971 Plymouth Valiant 2dr. Hard Top same as a Scamp, sharp and cool Bumble Bee Stinger Yellow with nice Black vinyl top and rear... More
1932 Plymouth Four Door Sedan ready for restoration. Vehicle is complete, but separated in parts. Straight body, all original steel, never wrecked. Original wood... More
Solid car 318 V-8 Automatic Has a mild cam Runs and sounds good Would make a easy fixer upper... More
1965 Plymouth Fury III for sale in our Chicago Showroom. This well-kept 1965 Fury III is powered by a numbers matching 5.2L 318... More
1954 Plymouth Savoy 4dr. sedan, refinished in correct Avalon Blue poly with a two tone blue interior. Powered by Plymouth's flathead 217 ci. 100... More
1965 Plymouth Barracuda Sport Coupe very desirable body style with large back windshield, only 51k actual documented miles, strong detailed slant six-cylinder, factory three... More
All original 1968 Plymouth Fury III 4-door sedan. The car is in amazing condition, having had four loving owners over the last 45 years.... More
1974 Plymouth Duster rebuilt 318 rebuilt with 2000 miles, 727 Auto Trans. Manual Disk Brakes, New Power Steering Pump, New Steering Box, New Alternator,... More
1946 Plymouth P15 Special Deluxe 2 door sedan, Original flat head six, 3 speed manual. 6 volt system. Interior redone (with original wool pin stripe seats... More
1970 Plymouth Fury Gran Coupe - Cream of the Crop, this 1970 Plymouth Fury Gran Coupe is one-owner with only 73,000 actual miles. Consistently... More
1969 Plymouth Fury 3, convertible. Engine is a 318. Blue color. Car is fully refurbished, so not sure mileage is 100% accurate. Fun... More
1976 Plymouth Valiant two-door Brougham edition, unrestored survivor. The car has 47,000 original miles on its 225CID slant-six engine from one owner, and has... More
1940 Plymouth coupe 80,000 miles - 6-cylinder 6 flatty Car was stored inside for years. Interior ok, also have original interior with car. Lots of new... More
1959 PLYMOUTH BELVEDERE $9,950.00 ONE OWNER . . . . SUCH A FIND! Owner Bought Auto in 1959 from Fred Oakley Motors in Dallas, Texas ALWAYS A... More
All vehicle trades considered, including classics and performance. Here is a very neat 1948 Plymouth Special Deluxe sedan. This was the the top-of-the-line for Plymouth... More
suicide rear doors, nice paint and chrome, good seats, new brakes, tires, and battery, flathead six, 74,xxx mi, runs great... More
1949 Plymouth Special Deluxe two door coupe,just out of a prolonged museum stay.This is a solid,unaltered,original paint car,with an excellent interior,that runs and drives... More
1951 Plymouth Belvedere 2dr HT coupe, rare body style, most all orig int, 4 newer www tires, six cyl, 3spd, runs and drives. ... More
1956 Ply Belviedere Sed, 2 owner, all orig, solid car, nice int w/ new seat covers, 85,xxxmi, good running 6cyl, 3spd, well maint, runs and... More
PLYMOUTH: 1966 Fury III convertible, red, fair condition, garaged, 318 ci engine, road ready, 88,000 miles, $8,000 obo. 845-279-6260, NY; [email]... More
PLYMOUTH: 1964 Fury 4-door, original, beautiful one-owner, 318 engine, 73,900, always garaged, primered, rare find, $5,895. 719-543-4325, Pueblo, CO.... More
1965 Plymouth Fury III 2-door, 318 ci, excellent condition, auto trans, white exterior, burgundy interior, 135,000 miles, $9,800 obo. Ed, 214-762-0918.... More
PLYMOUTH: 1966 Belvedere convertible, less than 2,500 produced, drive as is or restore, $6,500, located in Brainerd, MN; call for information. 406-672-5344, MT.... More
PLYMOUTH: 1964 Valiant station wagon, restored, V100 custom, 225 3-speed standard, radio, heater, excellent condition, drive home, $9,595 firm. 607-432-7439, NY.... More
PLYMOUTH: 1964 Valiant Signet, bucket seats, slant 6, auto, ps, new interior, new paint, nice running/driving car, $5,995. 719-561-8759, CO.... More


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Temple Run
Imangi Studios
The addictive mega-hit Temple Run is now out for Android! All your friends are playing it - can you beat their high scores?!
You've stolen the cursed idol from the temple, and now you have to run for your life to escape the Evil Demon Monkeys nipping at your heels. Test your reflexes as you race down ancient temple walls and along sheer cliffs. Swipe to turn, jump and slide to avoid obstacles, ...
Download this app if:
you want a great running game on you smartphone or tablet.
App Rating
Arcade & Action
Updated: June 25, 2013
Publisher: Imangi Studios
Version 1.0.8 [24.117248 MB]
Feel like Indiana Jones by JennyMurphy
This is a super fun, super addictive adventure game in the vein of Indiana Jones. Great time killer and really gets you motivated for a higher score! Lags sometimes, otherwise it would be 5 star.


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The Clinic at Walmart operated by Baptist Express Care
Do you want medical care fast? When it fits your schedule? At a price you can afford?
At Baptist Express Care we want to make healthcare accessible and affordable. With our transparent prices and convenient locations, we bring healthcare to you the consumer. With locations throughout the state of Kentucky, we exist to better serve our community by bringing healthcare to where you shop.
Please click here for a complete listing of Baptist Express Care locations.
- Fast, affordable access to services such as screenings and treatment of minor illnesses and injuries.
- Walk-in clinic. No appointment necessary.
- Prices are clearly posted so you always know the cost before treatment.
- Provide services to patients 24 months of age and older.
- Patient care delivered by licensed, board certified providers who diagnose, treat and prescribe non-narcotic medication.
- Help in finding a physician or talking with your own doctor.
- Patient information is recorded electronically so you spend less time filling out forms.
Cash, credit/debit cards accepted. Most major insurance plans are also accepted.
We're near you.


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Galaxy is preparing yet another GeForce GTS 250 SKU, this one labeled "Cool Edition", owing to its design that focuses on the GPU cooler. The card uses the usual Galaxy shade of blue colour. The PCB holds a 5-phase VRM for the GPU and memory, and is cooled by dedicated heatsink. The center of attraction is the GPU cooler, which looks elliptical. From its central GPU contact base made of copper, arise several radially-projecting, forked aluminum fins. Nested in a plastic shroud is an 80 mm fan for active cooling, while the memory cools directly under its airflow. This card comes in two variants based on memory size: 512 MB and 1 GB. It uses fairly standard clock speeds of 702 MHz (core), and 1000 MHz (memory). Output connectors include DVI-D, D-Sub, and HDMI with provision for audio routing from your sound-card. The card can pair with two more of its kind (or GPU at least), for 3-way SLI. Expect standard pricing when this hits stores soon. Source: Expreview
there are like 40 variations of this same GTS250 each promising 'groundbreaking performance' what is the point? they should add a newer cooler as revised version to the cards
It's time for a NEW PSU standard with the PSU providing a new connection for the graphics card. A higher current lower voltage connector. Why? Dont need such large/expensive VR on the GPU card making GPUs cheaper and less waste on upgrade... we all upgrade GPUs more often than PSUs. Second, keep the VR heat away from the GPU and mainboard by having most of the "hard work" done with transformers/regulators than just DC regulators alone on the GPU. More efficient, and cheaper overall setup. Third, GPU cards would now be shorter giving us less problem with installing them in tight spaces. Fourth, reduces airflow restrictions in the case also. What a win-win.
You should be working for whoever makes the standards up. Assuming that works because I have no idea if it does or not.
ANOTHER WASTE OF MANUFACTURING COSTS there are already various gtx250 on the market and viable alternatives to the gtx250. YES, this is that WTF edition we have been waiting for.
i think it actually looks good. every card u see now that is different from the reference design is usually black with a black and/or white cooler. i think the blue looks good imo so poo on u Bo$$
Newegg has it. I don't understand the point - GTS 250's been out (in this guise) for six months or more and there's really nothing compelling there vs. any other GTS 250. http://www.newegg.com/Product/Product.aspx?Item=N82E16814162034 If I were in the market for one of those I'd get this: http://www.newegg.com/Product/Product.aspx?Item=N82E16814127423 OC'd a bit, cheaper and a little more interesting cooler.
lol init just, and with no real advantage over its older version that i can see other than a marmite cooler. i thought the die shrink would allow higher clocks but there still arent many that have higher clocks than my 2 year old msi nx8800 gts 512
8800GTS 512s were more then capable of running faster then 9800GTX+'s if not matching the same clock speeds.


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Item 784649
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Best Uses
Comments about Topeak Handy E-Pack:
I purchased my Handy E-pack from the Bailey's Crossroads, VA store in 2009 to use on my Scott SUB 10 to hold my old Blackberry because the cell phone holder was too small. I've changed phones to an Iphone and the E-pack works for it as well. I'm going to get one soon to put on my Specialized rockhopper. I haven't had any issues with velcro quality or plastic attachment deterioration. I noticed this February that the exterior is beginning to discolor from exposure. I don't know if this reflects the high quality of the materials or that I need to ride more!
Best Uses
Comments about Topeak Handy E-Pack:
This will accommodate my large PDA phone (Blackjack with attached headphones) along with my compact digital camcorder, ID and credit card. I have attached the E-Pack to my handlebar stem so that I can listen to music and answer calls while on long rides without having pockets on my bike clothes.
I purchased it because it is the largest cellphone/electronics holder at the local REI. I am largely happy with it. It holds what I need and is secure.
Two things that should be improved: The Velcro will probably wear out within a year's use; I wish it had come with a clip. 2) The plastic mounting band that came with the product is low-quality; it broke before I could get the band tight enough to secure the QuickClick Fixer. I used a metal hose clamp in its place - much stronger and about the same weight.
Best Uses
Comments about Topeak Handy E-Pack:
This bag is very well made; compact but stretchable. Its height is 4 3/8" if the flap is folded all the way; however, if you don't close the flap all the way, you get 6/8" more room on top (the big piece of velcro provides secured closure even if the flap is not folded all the way.) The width is 3 1/4". The depth is only 1 1/2" NOT 2.9" as described and I don't think it can stretch that much. It can hold my car key, whistle (size of a 1.5" long pencil), [$] bill, a copy of the driver's license, a copy of the insurance card, my Blackberry Pearl, my digital camera (3.5" x 2.5" x .75"). The bag can be worn around one's neck, although I did not get a shoulder strap as stated under product specs, very disappointed. The bag can also be installed on the stem of the bicycle using the ring provided, very easy on and off. I am beginning to like Topeak - excellent quality products!
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Degree | Bachelor of Science |
Official Length of the Programme | 10 Semesters |
Accreditation | accredited by ASIIN in 2007 |
Begin of study | no longer possible |
no Numerus Clausus |
Deadline of application | no longer possible |
Study fees | € 228,- per Semester |
Location | Sankt Augustin
* Under certain circumstances a later application may be possible until Oct. 30.
The part time version of the Bachelor of Computer Science Degree Programme is no longer on offer for applications!
Take a look, if you want to get an impression on what the official every day student life is like at our department.
The so called Studienverlaufsplan shows the curriculum with all the groups of modules and all the courses that are part of the degree programme as well as the exams and the credits earned.


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About Fannie Mae
Help For Homeowners
Fannie Mae was established as a federal agency in 1938, and was chartered by Congress in 1968 as a private shareholder-owned company. On September 6, 2008, Director James Lockhart of the Federal Housing Finance Agency (FHFA) appointed FHFA as conservator of Fannie Mae. In September 2008, we also entered into an agreement with the U.S. Department of Treasury that was most recently amended in December 2009. Under the agreement, Treasury will provide us with capital as needed to correct any net worth deficiencies that we record in any quarter through 2012. The agreement is intended to ensure that we are able to continue providing liquidity and stability to the housing and mortgage markets.
Fannie Mae operates in the U.S. secondary mortgage market. Rather than making home loans directly to consumers, we work with mortgage bankers, brokers and other primary mortgage market partners to help ensure they have funds to lend to home buyers at affordable rates. We fund our mortgage investments primarily by issuing debt securities in the domestic and international capital markets.
Fannie Mae has three lines of business—Single-Family, Multifamily and Capital Markets—that provide services and products to mortgage companies and a broad range of housing partners. Together, these businesses contribute to the company's chartered mission to increase the amount of funds available in order to make homeownership and rental housing more available and affordable.


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Sun Java Cologne
By Franck Olivier for Men
Sun Java Cologne by Franck Olivier All products are original, authentic name brands . We do not sell knockoffs or imitations.
2.5 oz Eau De Toilette Spray
Item #500571
In Stock, Ships within 10 hours
Hurry! Only 8 in stock
More Franck Olivier fragrances
for Women: Franck Olivier Club , Franck Olivier , Forever Franck Olivier , Sun Java , Passion Franck Olivier , morefor Men: Sunrise Men , Eau De Passion , Blue Touch , Temperament , Sun Java White , more
See all Franck Olivier products
Customer Comments
I got what I ordered when I expected it, and I got it at a great price. I will use them again.
M. Rebelo (Manhattan Beach, CA)


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Armada TSTW Skis
- Lengths: 156, 165, 174
- Dimensions: 118 - 131 - 101 - 122 (@174)
Product Info:
The TSTw is a beautiful hybrid of the VJJ rockered powder profile and a traditional all-mountain ski. The ski's stiff, non-rockered tail allows ideal edge hold, speed control and stability, and the rockered tip makes skiing pow as easy as skiing the groomers. As with the TST, a portion of the proceeds of this ski are donated to Travis Steeger's Memorial Fund and the Avalanche Awareness Beyond the Boundaries Society.


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Release Date: December 11, 2001 |
DOE-Sponsored Process Enhances Use of Landfill
Gas, Improves Air Quality Energy Secretary Abraham Commends Small Business for Innovative Concept Being Showcased Today in New Jersey |
COLUMBUS, NJ - Acrion Technologies Inc., a small business sponsored by the U.S. Department of Energy, is showcasing a method this week that could offer a major advancement in reducing pollution at municipal landfills where Americans deposit more than 100 million tons of garbage every year.
The garbage creates a major source of air emissions, expelling carbon dioxide (CO2) and methane as it decomposes. At an open house today at the New Jersey EcoComplex, Acrion is demonstrating how its innovation will make it easier to capture the CO2 before it escapes into the atmosphere and to use the captured gases for commercial ventures, making such "landfill gas-to-energy" projects more environmentally and economically attractive.
"Acrion took a good idea and, in partnership with the federal government, made it work," said Secretary of Energy Spencer Abraham in congratulating the company. "It will be creative ideas like this one that will be key to improving the quality of our environment and combating the threat of climate change. The Department of Energy is pleased to have had a role in fostering the development of this technology and helping it evolve to the threshold of commercial reality."Acrion, based in Cleveland, Ohio, received a small business innovation research grant from the Energy Department in 1998. With the federal backing, the company developed a process called "CO2 Wash" which it initially tested at a New York site.Now, with follow-on funding from the department's National Energy Technology Laboratory, the company has scaled up the process at the New Jersey EcoComplex. Acrion's first step to commercialize the innovation will be seen at an open house today where visitors touring the EcoComplex will have an opportunity to see and ask questions about the Acrion CO2 Wash system. Since it began operating this summer, the system has been processing gases captured from decomposing waste at the Burlington County landfill. After moisture is removed, the gases are compressed and fed into the bottom of the unit's three-story high column. As the gases drift upward, refrigeration at the top of the column condenses the CO2 into liquid form. A portion of the liquid CO2 washes down the column, cleansing volatile organic contaminants from the gas. Clean, high-grade fuel gas exits the top and can be used directly in turbines, boilers or fuel cells to generate electricity. Methane produced from Acrion's CO2 Wash is 2 to 3 times cleaner than required by fuel cells which can convert the hydrogen-rich gas into electricity without using combustion. The landfill gas could also be further processed into methanol or upgraded to pipeline specifications, depending on local market needs.The small stream of contaminant-laden CO2 that is used to wash out impurities in the landfill gas is vaporized and burned in a flare to destroy the volatile organic compounds.The CO2 not used for the wash is drawn off as a 99.99 percent pure liquid CO2 stream that can be used in a variety of commercial applications, from making dry ice to carbonating soft drinks. One option Acrion is examining is to pipe the CO2 to Burlington County's R&D Greenhouse and Resource Recovery Complex, where "Jersey Fresh" tomatoes and other plants would benefit from the CO2-enriched environment. Acrion is also providing samples of the pure liquid CO2 to distributors and consumers for analysis and testing in commercial applications.Acrion's innovation is expected to add to the growing interest in using landfill gas as a renewable energy resource. Current federal law requires many landfills to collect the gas and dispose of it in one of two ways: either flare the gas, or install a "landfill gas-to-energy" system.According to the Environmental Protection Agency, every 1 million tons of waste deposited in landfills produces enough landfill gas to generate 7 million kilowatt hours of electricity per year, enough for 700 homes. Using this gas for energy purposes, rather than expelling it into the atmosphere, is equivalent to removing more than 6,000 cars from the road, or planting 8,300 acres of trees. |
Contact: David Anna, DOE/NETL, 412-386-4646 |


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2010-10-24 14:28
Global Best Brands in Korea (2)Deloitte Anjin About the brand Deloitte Anjin is the Korean member company of Deloitte Touche Tohmatsu Limited, one of the world's foremost professional organizations in audit and consulting services. Sharing the global expertise and resources of Deloitte, the Seoulbased outfit provides clients with world-class services in the areas of audit, tax, financial advisory and enterprise risk services. The firm says approximately 2,000 employees of Deloitte Anjin are committed to offering services which exceed clients' expectation and thereby helping them excel in a globally competitive environment. CEO Name: Lee Jae-sool Career: Lee has 30 years of professional experiences in financial services. Based on his rich experiences, he took charge of Deloitte Anjin last year. His expertise includes merger and acquisition (M&A) strategy, post-merger integration and restructuring. Education: Ph.D. at Dankook University Extracurricular: Golf, traveling Competitive position Deloitte Anjin is regarded as a top-tier accounting company in Korea and it has expanded its business horizon to various areas such as consulting and tax services. During the fiscal year 2009, which wrapped up this March, the outfit chalked up 238 billion won in sales and the figure increases to 263 billion won when those of its subsidiary Deloitte Consulting are included. The figure represents a 14-percent growth on a year-on-year basis, which is the biggest in the domestic industry. It says that it retains the top position in the market share on accounting services for the country's 100 largest corporations. Long-term goal Anjin, whose heritage stretches back about 25 years ago, has a bold goal of posting an annual growth rate of 20 percent over the next five years to reach 520 billion won in turnover by 2015. Toward that end, it plans to strengthen its capacity in the nonaudit segments like advisory, M&A, consulting and tax. "We aim to create unique corporate cultures of pragmatic innovation, continual challenges and participation/ cooperation to make the organization the most loved one by clients and top talents," Deloitte Anjin CEO Lee Jae-sool said. Boehringer Ingelheim Korea About the brand The Boehringer Ingelheim (BI) group is one of the world's top 20 pharmaceutical companies, posting 12.7 billion euro in net sales last year — 20 percent of which was spent on research. The global behemoth founded its subsidiary BI Korea in 1976, and has remained committed to supplying and marketing innovative products in prescription medicines, consumer health care and animal health products. BI Korea has set an example of as a socially responsible company here as amply demonstrated by its support for the Wunsch Medical Award aimed at promoting academic performance in the medical field. CEO Name: Guenter Reinke Career: Reinke got aboard BI in 1980 and has assumed a variety of responsibilities at different posts. He has worked at BI Korea since 1997 and took the helm of the company in late 2003. Reinke was awarded honorary citizenship by the Seoul Metropolitan Government last year. Education: Studied economics and psychology at the University of Hagen and Dortmund. Extracurricular: Soccer, tennis Competitive position BI Korea is one of the best-known global pharmaceutical companies thanks to its smart advertising strategies and seamless efforts in contributing to society over the past few decades. Its growth rate is impressive — the German drug manufacturer recorded annual growth of 14 percent in the Korean market during the first decade of the new millennium. One of its flagship products is the constipation pill "Ducolax." Other core products include the antihypertensive drug "Micardis," and anti-spasmodic "Buscopan." Long-term goal Global drug companies are typically busy importing their mother company's products to the local market, but BI Korea has a different approach as showcased by its proactive research activities here. Under its vision of "value through innovation," BI Korea increases investment and support in the Korean market every year, channeling upside of 20 percent of overall revenue on clinical research. The number of international clinical tests that BI Korea has commissioned here were 46 this year, up from 13 in 2007, in a flurry of areas including diabetes and respiratory diseases. AIA Life Korea About the brand AIA Life Korea is one of the leading global brands in the domestic insurance market. AIA is the subsidiary of the American International Group (AIG), the insurance company based in New York. AIA Life Korea started operations in 1987, initially as a branch of ALICO. It was reorganized as a branch of AIA in 1997 and began operating under the name of AIG Life Korea three years later. The company returned to its original name of AIA Life Korea last year. Although the insurer changed its operating title a few times, its strong footing in the local market has remained unchanged. CEO Name: Lee Sang-hui Career: Lee joined ALICO in 1992 and took charge of AIG Global Investment Corp. Korea in 1997. He worked as chief financial officer of AIG Life Korea in 2002 before taking leadership of the company midway through 2007. Education: MBA at American Graduate School of International Management Extracurricular: Marathon Competitive position During the fiscal year 2009, which ended this March, AIA Life Korea captured approximately 15 percent of the market for total premium income earned by foreign life insurers, according to the Korea Life Insurance Association. The Seoul-based outfit had more than 2 million individual customers and roughly 3.1 million in-force policies as of the end of this fiscal year to stand out as one of the top global brands here. It brought advanced management and business knowhow based on the experience in overseas markets. Hence, it is touted as ratcheting up the level of the local insurance industry as a whole. Long-term goal AIA Life Korea has gained its reputation thanks to unique risk management and a mid- to long-term business strategy, which helped the corporation keep a transparent and stable financial structure. On top of such conventional strengths, AIA Life Korea jockeys to win the hearts and minds of customers through tailor-made products satisfying their tastes. "We put the needs of our clients first. Hence, we will continue to develop innovative products in line with the changing trends of business so that our customers can be happy," an AIA Life Korea official said. BMW Korea About the brand As a leading global automotive brand, BMW Group Korea has headed exploration of the domestic market, which has been controlled by homegrown outfits for a long time. BMWs have been available here since 1987 when a local dealer brought the vehicles and sales started upward sharply midway through 1995 after BMW Korea was officially launched. After accommodating Rolls-Royce in 2004 and MINI the next year, the company was renamed BMW Group Korea and has shown an unparalleled performance among global automotive brands here. CEO Name: Kim Hyo-joon Career: Kim was one of the founding members of BMW Korea. Since taking charge of the company in 2000, Kim has headed the carmaker to become the primary player in the hard-fought local market. Education: Ph.D. at Hanyang University Extracurricular: Golf Competitive position BMW positioned itself as a premium brand via proactive marketing efforts as well as various corporate social responsibility programs. As far as sales are concerned, the outfit has been also been unrivaled. BMW sold more than 7,800 vehicles during the first half of this year to break the half-year record among import competitors and looks to reach the 15,000 mark for 2010 overall. The entity is expected to achieve the goal without difficulty as its sales already topped 12,000 as of the end of last month. No other global automaker has ever passed through the 10,000 plateau in a year. Long-term goal BMW Group Korea puts sustainability and corporate social responsibility first so that the company can continue to rack up growth while making substantive contributions to society. Under the philosophy, the outfit launched its BMW Apprentice Program in 2004, under which it trains engineers based on its cutting-edge technology. Some of them win opportunities to work for BMW. It also donates vehicles to universities and high schools so that they can work on the best cars. This summer, it offered a total of 15 automobiles to coincide with its 15th anniversary. Alcatel-Lucent Korea About the brand Alcatel-Lucent is a leading global high-tech company providing endto- end solutions for next-generation networks to service providers and enterprises. Its partners also include strategic industries and governments. Alcatel-Lucent is a combined company formed through the high-profile merger between two top-ranking corporations — Alcatel and Lucent Technologies — in late 2006. Alcatel-Lucent has contributed to Korean communications development since 1979 when it waded into the domestic market. The outfit has supplied a broad range of networking solutions and services to telecom operators. CEO Name: Shin Won-ryul Career: Shin started his career at KT in 1978 and worked for the fixed-line operator for 18 years before joining Nortel Networks Korea in 1996. After working for some other global outfits, he moved to Alcatel-Lucent Korea in 2007 and took the reins of the firm in early 2009. Education: Bachelor's degree in English language and literature from Soongsil University. Extracurricular: Music, bicycle Competitive position Alcatel-Lucent Korea is regarded as the foremost foreign company in the industry as it has supplied the largest number of networking solutions to service providers here. It is the only overseas vendor, which supplied both second- and third-generation networks to the domestic market and spearheads the development of futuristic networks dubbed long-term evolution (LTE). The outfit is also famous for its research arm of Bell Labs, which opened Bell Labs Seoul late last year in cooperation with Seoul Metropolitan City and Korea University in Seoul aimed at supporting the development of Korean innovations. Long-term goal On the back of experience and know-how of more than 30 years here, Alcatel-Lucent Korea aims to become a strategic partner to domestic clients, which work on communications network transformation. "We will put forth efforts to maintain our leadership in such markets as wireless, optics and Internet protocol solutions as well as play a pivotal role in the country's shift to fourthgeneration networks," Alcatel-Lucent Korea head Shin Won-ryul said. "In addition, we jockey to seamlessly contribute to the fast developing local information technology industries through proactively cooperating with our clients and partners." |


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Because Knetbooks knows college students. Our rental program is designed to save you time and money. Whether you need a textbook for a semester, quarter or even a summer session, we have an option for you. Simply select a rental period, enter your information and your book will be on its way!
Part One Basic Two-Dimensional Entities
CHAPTER 1 Lines and Essential Tools
CHAPTER 2 Circles and Drawing Aids
CHAPTER 3 Layers, Colors, and Linetypes
CHAPTER 4 Templates, Copies, and Arrays
CHAPTER 5 Arcs and Polar Arrays
CHAPTER 6 Object Snap
Par... MORE
CHAPTER 7 Text
CHAPTER 8 Dimensions
CHAPTER 9 Polylines
CHAPTER 10 Blocks, Attributes, and External References
Part Three Isometric Drawing and Three-Dimensional Modeling
CHAPTER 11 Isometric Drawing
CHAPTER 12 3D Modeling
CHAPTER 13 More Modeling Techniques and Commands
APPENDIX A Drawing Projects
APPENDIX B Creating Customized Panels
APPENDIX C Menus, Macros, and the CUI Dialog Box
APPENDIX D Additional Tools for Collaboration


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A+ A+F Academic Flexibility: Very easy to transfer credits from other colleges to CCAF, including CLEPS and DANTES.
A+ A+F Career Services: CCAF is just for Associate's degree and helps many students transfer credits from their CCAF towards a Bachelor's degree at another college.
Career Services: When enrolled in CCAF you are also employed by the USAF so the post grad services of this school are the same as if regularly employed by the Airforce and having completed your CCAF it makes no difference.
Academic Experience: The Developmental Psychology course as taught by Julie Buckman was completely useless and there was not real knowledge to be learned, other than about Julies so called mental health issues and the history of her life. If you want an easy grade and don't care about actually learning anything, take one of her classes.
A+ A+F Campus Resources: Economically Delightful and Productive – The Air Force bases have various programs such as intramural sports, recreational parks and activities at little to no cost to airmen and their families, and helpful departments locted thr
A+ A+F Campus Resources: The Facilities Are Great – Although the Community College of the Air Force isn't a real college, the varies education centers and libraries are state-of-the-art facilities. Not only do they provide countless educational resources, they also have faculty and staff who steer airmen in the right path and spend countless hours counseling and advising them. Aside from those facilities, the Air Force bases also have a diverse amount of coffee shops, restaurants, low cost grocery stores also known as the commissary, tax free base exchanges, exercise facilities, movie theaters, various dining halls, dormitories, atheletic fields, and shoppettes. It's definitely a great experience to have such a variety of places to relax, study, communicate and observe.
A A+F Student Body: Self Paced – I am able to complete my degree at my own pace because I find the college to attend and send my transcripts to CCAF in Colorado to be added to my degree plan.
A+ A+F Overall Experience: Although I have not gone to the campus because I was automatically enrolled in the college, but the customer service is execptional and it is a regionally accrediated school my AA degree will be accepted at any Major University.
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Maple 71" Left Angle Corner Desk:
- The 71" Left Angle Corner Desk is constructed of thermal fused melamine laminate and finished with a 3mm matching PVC edge
- The desk offers a storage area for your CPU tower and strategically placed grommets that offer access to all your technological needs
- Includes 2 wire management grommets, CPU Box and shelf
- It includes adjustable glides for leveling
- Constructed of thermal fused melamine laminate
- Finished with a 3mm matching PVC edge
- CPU tower
- Strategically placed grommets
- Material: Laminate
Finish: Maple
71"L x 71"W x 29"H
Collection: Regency Legacy Office Furniture
Furnished Over 1 Million Homes Since 1997...
Product Review - Regency Maple 71" Left Angle Corner Desk
Furniture Brand
Weight & Size
Exclusive 180 Days Lowest Price Guarantee
Guaranteed lowest prices online! We will beat any lower price online within 180 days of delivery. Shop with total confidence & discount pricing! One Way Furniture is the Quality Bar Stools, Discount Furniture, and Office Furniture Superstore. We will not be undersold! *Restrictions include close outs, auctions, and out of stock items.
Reference - Sku: ROF-ST-LADSL7130-PL - Regency Maple 71" Left Angle Corner Desk by Regency Inc. Office Hospitality Solutions


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ZOTAC's GeForce GTX 680 Extreme Edition is shaping up to be a monster. A preview by Expreview points out its clock speeds out of the box to be 1.20 GHz (base and boost), with memory staying at 1.50 GHz (6.00 GHz GDDR5 effective). The default core voltage is 1.212V. ZOTAC also told the source that the card is capable of delivering 1.5V core voltage to assist in extreme-overclocking. It also goes on to claim that 2.00 GHz core clock speed might just be possible, in the best case scenario (you have the best cooling, best overclocking skillset, best luck). Apart from a strong VRM (detailed in the older article), the card is also backed by several nifty features, such voltage measurement points, extreme-cooling optimized BIOS, and adequate-looking VRM cooling. The USB mini type-B connector on the back of the card turns out to be not a connection to an OC module, but a USB connection to the motherboard. ZOTAC is routing the card's SMBUS to its Firestorm OC software over USB. Maybe they haven't figured out [how] this could be done through the NVIDIA driver interface, or they didn't trust NVIDIA. For example, NVIDIA blocks SMBUS access to components that they deem "sensitive". More pictures, and videos follow. The videos are in Chinese language. Source: Expreview
Probably $550-575. I would imagine Nvidia wants their Overclocked GTX680's to cost about the same as reference HD7970's if AMD refuses to budge on price.
AMD refuses to reduce the price because GTX680 is vapor ware now,and not because 680 is less powerful.
I think you need to learn terminology.... vaporware would mean that it pretty much didnt even exsist (Phantom console anyone?).
Just curious, you had 7970 as far as I remember from other posts. How do you compare the 680 to the 7970?
Hate to say it, but its day and night difference. Not necessarily in performance but driver stability. I had a lot of issues with eyefinity locking up and the catalyst controller being a pain in the ass. Also, some games had seriously hard time running two 7970's. From my understanding a lot of the performance issues have been ironed out though. As for the 680's I love them to be honest. The fan is so darn silent even in SLI in a Corsair 800D case which is terrible for air cool they still run fairly cool and perform great. Also, the Nvdia control panel is on average 10 thousand times faster to respond. I dunno not a brand fanatic, but I must say I was very let down but I will keep an open mind when I upgrade next time. Still have the stupid water blocks I was gonna use :-(
This is why at similar performance levels AMD must have lower prices, NVIDIA brings a much more mature software support.
you can find it in this post's comments http://www.techpowerup.com/163231/ZOTAC-GeForce-GTX-680-Extreme-Edition-Pictured.html
ZOTAC, Colorful and possibly MSI have most of my attention with their custom 680s, But i want more reviews before i can be sure who of them gets my money. I hope to see TPU reviews of some of the more awesome custom 680s.


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hi everyone!!!im looking for mom friends... i live in texas and have two kids (4 years boy and 3 weeks girl).
Welcome! I have three girls (4,3 and 1) and you will have no problems finding lots of friends on Strong Moms.


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A tour de force through blues & gospel jazz gems, luscious love songs, pulsating samba rhythms – and a stunning duet with 3-time GRAMMY nominee Gerald Clayton."Flawless. Ryan's tone, phrasing, and interpretive smarts are impeccable, and her range – sublime."— JAZZTIMES"An astonishing contralto voice… Every lyric Ryan sings is delivered with the deepest conviction."— DOWNBEAT"Superb. Mile deep emotional depth. Ryan's rhythmic sense is uncanny.' — AllAboutJazz
Tags: Jackie Ryan, Listen Here


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Best of New England
UConn Dairy Bar Named a 2013 "Best of New England - Editor's Choice" Winner by Yankee Magazine
Voted Best Ice Cream in Connecticut!
UConn Dairy Bar ice cream makes the "Best of Connecticut: 2012" list! Read the article here!
51 Great Ice Cream Parlors
The University of Connecticut gets back its ag-school roots at the UConn Dairy Bar in Storrs, where you can order your cone, sundae or shake and then walk out back to Horsebarn Hill to toast the cows that made it all possible.
51 Great Ice Cream Parlors USA Today
Store: 860-486-1021
Office: 860-486-2634
3636 Horsebarn Hill Rd Extension
Department of Dining Services
Box U-4263
Storrs, CT 06269
Facebook: Uconn-Dairy-Bar
Fall Hours:
Sunday – Thursday 11am – 7pm
Friday & Saturday 11am – 10pm
Why Try It?
Treat yourself to a famous UConn tradition by trying some of our locally made ice cream! Over 200,000 customers visit the Dairy Bar annually to enjoy more than 24 flavors of ice cream created right here at the Dairy Bar. The Dairy Bar still manufactures ice cream according to its original and recipe from the early 1900s. Perhaps our most famous flavor is "Jonathan Supreme", named for the school's mascot, Jonathan the Husky Dog (vanilla ice cream swirled with peanut butter and chocolate covered peanuts).
Made Before Your Eyes
During your visit to the UConn Dairy Bar you may even have the chance to observe ice cream being made! Call for our ice cream production schedule at 860-486-2634 or 860-486-1021.
If you have questions about ice cream, the UConn Dairy Plant, or a arranging an educational tour, please contact the Department of Animal Science- Dairy Manufacturing Unit at 860-486-0569. Please recognize that as a working production facility, we are only able to provide tours with significant advance notice.


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New FC Item & Renewal Info
Hey everyone! The amazing new Deluxe Fan Club Membership package is up in the store now! There are three different packages to choose from this year -- digital-only, the basic Fan Club Membership, and theDeluxe Fan Club Membership, which includes....
drum roll please......
a Nick Carter Bobblehead!! Yes it's true, you can FINALLY get your hands on one of these exclusive, limited run bobbleheads available only to fan club members. Hurry and snatch one up before we run out!
As always, please feel free to reach out to us and visit support.groundctrl.com with any questions.
Thank you for being a Nick Carter Fan Club member!


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Address: 3811 Ray Street, San Diego, CA 92104 Call Us: (619) 255-6475
Artist Reception at Mystic Water with Dana Carson
Date:Jun 22, 2012
Time:7:30 PM
Come check out stunning nature photographs by Dana Carson!
Bio: Dana Carson began shooting nature photography a few short years ago. In her words, an "obsession" overtook her and she began shooting the gorgeous images she saw nearly everywhere she looked. She began striving to capture pieces of these beautiful moments of the world and to share them with others with hopes of helping others reconnect (or deepen their connection) with nature and all that is at stake, what might be lost, if we do not make changes toward a more eco-respecting way of living. She hopes to inspire others to make lifestyle changes, whether grand or seemingly small, which will protect our Earth and its inhabitants. Her images are viewable at Mirada Iluminada Photography and Artprintstopia, and will be on display at the Mystic Water Kava Bar beginning June 9th, 2012.
Artist reception for Dana will be held Fri June 22nd 7:30PM with guest DJ.
Next month:
Dirty Cello Sunday July 8th 9:30-11:30 dirtycello.com or chekc out youtube link on calendar page for her event,
Dirty Diamond will be performing for Ray at Night July 14 both acts you don't want to miss!


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Saturday night will be a chance for the nation to get their final look at Johnny Manziel as he tries to become the first freshman to ever win the Heisman trophy.
For the season, Manziel thrown 3,047 yards and run for 1,114 yards.
He has accounted for 38 touchdowns. The touchdown total is a school record.
Johnny "Football" is on pace to break the SEC total offense record set by Cam Newton in 2010, the same year he won the Heisman.
Manziel has given Aggies a lot to cheer about this season.
Here now is a look back at johnny football's Heisman moments.


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Looting Mali's History
As demand for its antiquities soars, the West African country is losing its most prized artifacts to illegal sellers and smugglers
- By Joshua Hammer
- Photographs by Aaron Huey
- Smithsonian magazine, November 2009, Subscribe
I'm sitting in the courtyard of a mud-walled compound in a village in central Mali, 40 miles east of the Niger River, waiting for a clandestine meeting to begin. Donkeys, sheep, goats, chickens and ducks wander around the courtyard; a dozen women pound millet, chat in singsong voices and cast shy glances in my direction. My host, whom I'll call Ahmadou Oungoyba, is a slim, prosperous-looking man draped in a purple bubu, a traditional Malian gown. He disappears into a storage room, then emerges minutes later carrying several objects wrapped in white cloth. Oungoyba unfolds the first bundle to reveal a Giacometti-like human figure carved out of weathered blond wood. He says the piece, splintered and missing a leg, was found in a cave not far from this village. He gently turns the statuette in his hands. "It's at least 700 years old," he adds.
Oungoyba runs a successful tourist hotel next door to his house; he also does a brisk business selling factory-produced copies of ancient wooden statuettes and other objects to the Western package-tour groups that fill the hotel during the winter high season. But his real money, I've been told, comes from collectors—particularly Europeans—who may pay up to several hundred thousand dollars for antique pieces from villages in the region, in defiance of Malian law. My guide told Oungoyba that I was an American collector interested in purchasing "authentic" Dogon art.
The Dogon, subsistence farmers who hold ancient animist beliefs, are one of central Mali's ethnic groups. In the 15th century, or even earlier, perhaps fleeing a wave of Islamization, they settled along the 100-mile-long Bandiagara Cliffs, which rise just above this village. The Dogon displaced the indigenous Tellem people, who had used caves and cliff dwellings as granaries and burial chambers, a practice the Dogon adopted. They built their villages on the rocky slopes below. Today, the majority of the estimated 500,000 Dogon remain purely animist (the rest are Muslims and Christians), their ancient culture based on a triumvirate of gods. Ritual art—used to connect with the spiritual world through prayer and supplication—can still be found in caves and shrines. Dogon doors and shutters, distinctively carved and embellished with images of crocodiles, bats and sticklike human figures, adorn important village structures.
On the porch of his private compound, Oungoyba, a Dogon, unwraps a few additional objects: a pair of ebony statuettes, male and female, that, he says, date back 80 years, which he offers to sell for $16,000; a slender figurine more than 500 years old, available for $20,000. "Check with any one of my clients," he says. "They'll tell you I sell only the real antiquities."
Two days earlier, in the village of Hombori, I had met an elderly man who told me that a young Dogon from the village had been cursed by the elders and died suddenly after stealing ancient artifacts from a cave and selling them to a dealer. But endemic poverty, the spread of Islam and cash-bearing dealers such as Oungoyba have persuaded many Dogon to part with their relics. Indeed, Oungoyba says he purchased the 700-year-old human figure, which he offers to me for $9,000, from a committee of village elders, who needed money to make improvements to the local schoolhouse. "There are always people in the villages who want to sell," Oungoyba says. "It's just a question of how much money."
The villages of Dogon Country are among hundreds of sites across Mali that local people have plundered for cash. The pillaging feeds an insatiable overseas market for Malian antiquities, considered by European, American and Japanese art collectors to be among the finest in Africa. The objects range from the Inland Niger Delta's delicate terra-cotta statuettes—vestiges of three empires that controlled Saharan trade routes to Europe and the Middle East for some 600 years—to Neolithic pottery to the carved wooden doors and human figurines made by the Dogon.
According to Malian officials, skyrocketing prices for West African art and artifacts, along with the emergence of sophisticated smuggling networks, threaten to wipe out one of Africa's greatest cultural heritages. "These [antiquities dealers] are like narcotraffickers in Mexico," says Ali Kampo, a cultural official in Mopti, a trading town in the Inland Niger Delta. "They're running illegal networks from the poorest villages to the European buyers, and we don't have the resources to stop them."
Mali's antiquities are protected—in principle. The 1970 Unesco Convention signed in Paris obligated member nations to cooperate in "preventing the illicit import, export and transfer of ownership of cultural property." Fifteen years later, Mali passed legislation banning export of what is designated broadly as its cultural patrimony. But the laws have proved easy to circumvent. It's not just poor villagers who have succumbed to temptation. About a decade ago, according to unconfirmed reports, thieves made off with the central door of the Great Mosque of Djenné, a market town in the Inland Niger Delta. The centuries-old wooden door, inlaid with gold, allegedly disappeared while it was being replaced with a facsimile to thwart a plot to steal it. The door, which may well have fetched millions of dollars, was likely smuggled out of the country overland, across the porous border with Burkina Faso.
Subscribe now for more of Smithsonian's coverage on history, science and nature.
Related topics: Crafts World History Crime Archaeology Historically Relevant Artifacts Neolithic 15th Century Africa Mali Towns and Villages
Additional Sources
"Tellem and Dogon Material Culture" by R. M. A. Bedaux, African Arts, August 1988.
Comments (3) |
One of the few remaining beautiful Sub Saharan cultures is at risk of losing its history due to poverty. I wish I could assist in preserving the artifacts and history of the Dogon tribe.
Posted by MansuMusa on March 23,2012 | 10:54 AM
I enjoyed reading this article. I have never been to Mali or Africa, but I feel as if I just returned from a trip there with the knowledge and images I obtained from reading this piece. It is unfortunate to learn that people seek personal gains at the expense of losing historical and cultural artifacts. Perhaps this reflects upon an even deeper issue-- survival. I suppose in a third world country such as Mali,where a majority of the population suffers from chronic hunger, sadly, bigger issues remain.
Posted by Sarah Sievert on November 12,2009 | 10:28 PM
I do not find it out of the ordinary for "business men" to act in a way that maximizes their profit. These townspeople are taking advantage of what they have easy access to, unfortunately in this case, it is precious artifacts of history. People are risking their lives trying to smuggle these artifacts, while living in a community that lacks control over the situation at hand. It makes it hard to differentiate between those who are doing good for their community and those who are tyrant against it, which I believe is the main premise to the controversy.
Posted by Will Steinert on November 10,2009 | 10:28 PM


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Black Tie Untied
December 9, 2013
Read about the weekend's events with Black Tie Untied, featuring Men, Whiskey and Watches, Hot Dogs & Cool Cats gala and Christmas in Candy Land.
FILM REVIEW: 'Out of the Furnace'
December 8, 2013
From the opening scene to the parting shot, 'Out of the Furnace' keeps you in its grip.
PHOTO GALLERY: 'The Lucky 6' Producer's Cut
December 8, 2013
Ringling College of Art + Design's Academic Center housed a full audience to see the unveiling of 'The Lucky 6' Saturday, Dec. 7.
THEATER REVIEW: 'White Christmas'
December 6, 2013
Christmas comes early at the Players with 'White Christmas,' which runs through Dec. 22.
WEEKEND BEST BET: Sarasota Craft Festival
December 6, 2013
Robarts Arena is full of more than 125 craftsmen (and women) Dec. 6 through Dec. 8 for the 4th annual Sarasota Craft Show.
HOT FLASH: Shoe Fever
December 5, 2013
Black Tie Assistant Editor Heather Merriman stopped by the exclusive, first-look Manolo Blahnik party Wednesday, Dec. 4, at Saks Fifth Avenue Sarasota.
Inherited identity
December 4, 2013
Florida life impacted the work of Sarasota painters William Hartman, Larry Stults and Wilfrid Berg. The influence lives on in their descendants, who decided to feature their elders' work in an exhibit.
Spotlight: Bill Schustik is Sarasota's wayfaring stranger
December 4, 2013
Bill Schustik will perform a free Christmas-themed concert Dec. 11 as part of the Sarasota Concert Association's Munchtime Musicales series.
- Dec
11 "American Troubador" Bill Schustik in a Munchtime Musicales Performance
12:00 pm - 1:00 pm - Dec
11 Let it Snow
5:30 pm - 10:00 pm - Dec
13 "Jazz at Two" with the Rodney Rojas Quartet
2:00 pm - 4:00 pm - Dec
13 Cirque Des Voix "Joy and Wonder"
7:00 pm - 5:00 pm - Dec
15 A Celtic Christmas
7:00 pm - 9:00 pm - Dec
20 Hasselbarth
6:00 pm - 9:00 pm - Dec
20 The Sarasota Ballet presents Program 3 | John Ringling's Circus Nutcracker
8:00 pm - Dec
21 The Sarasota Ballet presents Program 3 | John Ringling's Circus Nutcracker
2:00 pm
Paint the town red and green
This year, we won't just be on the lookout for the most festive holiday lights on the Key. We'll be on the prowl for anything that embodies the happiness of the holidays with our new "Spirit of the Season" contest. -
Pettingell tradition is as sweet as pie
For the sixth consecutive year, Pettingell delivered pies from Yoder's Restaurant in Sarasota to his customers at Thanksgiving. -
Former Key Club manager takes on new role
Former Longboat Key Club & Resort General Manager Michael Welly has a new gig.


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Airdrie gears up for flu season with clinics
It�s that time of year again, and officials from Alberta Health Services are encouraging all Airdrie residents to visit their local influenza immunization clinics throughout October and November.
Health officials are asking residents to get immunized to prevent the spread of flu this season. Five clinics have been set up within the County for those wanting to get the flu shot.
�The influenza vaccine isn�t just about keeping you healthy � it�s about keeping the people around you healthy too,� Health Minister Fred Horne said. �This vaccine reduces the spread of this illness and deaths in our province. It also helps reduce pressure on our emergency departments and on our health care system as a whole.�
The influenza vaccine is free to all residents six months of age and older and is available at the public clinics, some pharmacies and physician offices.
This year, a nasal spray will be available for children aged two to 17 years.
�Some people are skeptical of the influenza vaccine,� Dr. James Talbot, Alberta�s chief medical officer said. �What I say to those people is it can help reduce your chances of getting infected with influenza by up to 70 per cent. The vaccine is extremely important for people who want to feel better during the influenza season, whether you�re at work, at home with your family or on holiday.�
According to Alberta Heath Services, influenza causes amount to 20,000 hospitalizations and about 4,000 deaths in Canada each year. Children six to 59 months of age, pregnant women, those 65 years of age and over and people with chronic health conditions are at higher risk of developing complications from influenza.
Influenza immunization clinic will be held at the following location:
� City of Airdrie will host multiple clinics at the Town and Country Centre on Oct. 23 and 24 from 9 a.m. to 7 p.m., Oct. 28, 29 and 30 from 12 p.m. to 7 p.m., and on Nov. 6 and 7 form 12 p.m. to 7 p.m.
The Airdrie City View welcomes your opinions and comments. We do not allow personal attacks, offensive language or unsubstantiated allegations. We reserve the right to delete comments deemed inappropriate. We reserve the right to close the comments thread for stories that are deemed especially sensitive. For further information, please contact the editor or publisher.
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