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Canberra Times
It is a very important meeting since it must pave the way for the agreement that we all hope to reach in Copenhagen. This agreement probably represents the world's last chance to bring climate change under control before it is too late.
But as the United Nations gathers the world's environment ministers in Poznan, the economic underpinnings for a muscular new treaty appear shakier than ever. The executive secretary of the UN Framework Convention on Climate Change, Yvo de Boer, recently said in an interview that, ''yes, things have changed but I don't think anyone will show the stupidity to focus on the short term and ignore the long-term issue, because these decisions will be with us for 30 years.''
This statement also reflects the position of President-elect Barack Obama and the European Union. Both players have vowed to stick to commitments to cap emissions of carbon dioxide, arguing that government action and investing in new green technologies and renewable energy is a sustainable way to stimulate the economy and create new jobs: i.e. smart growth.
We have engaged as co-chairs in the climate initiative ''Road to Copenhagen'', which is an open and web-based network that calls not only for smart growth but for climate justice. We have committed to this initiative because we believe that the climate debate, and a new treaty, needs a more stringent focus on the human and social implications of climate change.
Most of the expected 2.6 billion rise in global population by 2050 will come from the poorest regions in the world. These are regions which have no convergent economic growth, are the most unstable politically and will be the hardest hit by climate change. Jeffrey Sachs speaks about the paradox of a unified global economy and a divided global society where the poverty trap is self-reinforcing, not self-corrective. It is an alarming trajectory which constructs a ''sustainability gap'' that must be addressed. It is clear that we will not be able to mitigate climate change unless we address poverty.
Climate change is happening now. We can see that the poorest people and countries, those least responsible, are being hardest hit. For example, Africa as a continent is responsible for 3.8 per cent of global CO2 emissions, yet the impact of climate change will be unfairly devastating.
The United Nations Development Program (UNDP) estimates that adaptation costs for developing countries are in the tens of billions per annum by 2050 they will amount to $US86 billion ($A128billion) per year. Absorbing the climate change impacts will hamper achievement of many of the UN Millennium Development Goals (MDG), including those on reducing poverty and child mortality and combating HIV/AIDS, malaria and other diseases.
At best, 1 per cent of the resources required are currently available via the levy on the Clean Development Mechanism. Therefore, in order to ensure climate justice and meet the MDGs, we need to develop innovative ways for capacity building and technology transfer. More importantly, we need to ensure that the funds available for adaptation measures in developing countries are fair and proportionate clearly reflecting the ''polluter pays'' principle, respecting human rights frameworks and gender equality: that is, climate justice.
Prevention is better than cure. Acting early makes sense, not least from an economic point of view. According to the 2007-08 Human Development Report issued by the UNDP, every dollar invested in pre-disaster risk management in developing countries can save seven. Hence, industrialised countries must take strong and immediate steps to increase assistance to the least-developed countries for adaptation.
While mitigation is global, adaptation is local. This is why a new climate agreement must place adaptation on equal footing with mitigation. Furthermore, it must address the issue of climate justice and human rights in a development perspective.
Achieving sustainability and a low-carbon economy will not only depend on technological innovation, but will require far-ranging social and political innovation. Let us not forget that technology does not have the ability to eliminate poverty, respect human rights, ensure gender equality, stop climate change and build a sustainable society people do. That is what the initiative Road to Copenhagen is about, and the agreement in Copenhagen must be about climate justice for all peoples. The Nobel Peace Prize laureate Wangari Mathai puts it very simply: ''There can be no sustainable development without an equitable development; and there can be no equitable development without gender equality.''
Mary Robinson, former president of Ireland and vice-president of Club of Madrid; Margot Wallstrom, vice-president of the European Commission; Gro Harlem Brundtland, former prime minister of Norway.
Vovler a la lista <<<<<


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Phineas Gage: Neuroscience's Most Famous Patient
An accident with a tamping iron made Phineas Gage history's most famous brain-injury survivor
- By Steve Twomey
- Smithsonian magazine, January 2010, Subscribe
Jack and Beverly Wilgus, collectors of vintage photographs, no longer recall how they came by the 19th-century daguerreotype of a disfigured yet still-handsome man. It was at least 30 years ago. The photograph offered no clues as to where or precisely when it had been taken, who the man was or why he was holding a tapered rod. But the Wilguses speculated that the rod might be a harpoon, and the man's closed eye and scarred brow the result of an encounter with a whale.
So over the years, as the picture rested in a display case in the couple's Baltimore home, they thought of the man in the daguerreotype as the battered whaler.
In December 2007, Beverly posted a scan of the image on Flickr, the photo-sharing Web site, and titled it "One-Eyed Man with Harpoon." Soon, a whaling enthusiast e-mailed her a dissent: that is no harpoon, which suggested that the man was no whaler. Months later, another correspondent told her that the man might be Phineas Gage and, if so, this would be the first known image of him.
Beverly, who had never heard of Gage, went online and found an astonishing tale.
In 1848, Gage, 25, was the foreman of a crew cutting a railroad bed in Cavendish, Vermont. On September 13, as he was using a tamping iron to pack explosive powder into a hole, the powder detonated. The tamping iron—43 inches long, 1.25 inches in diameter and weighing 13.25 pounds—shot skyward, penetrated Gage's left cheek, ripped into his brain and exited through his skull, landing several dozen feet away. Though blinded in his left eye, he might not even have lost consciousness, and he remained savvy enough to tell a doctor that day, "Here is business enough for you."
Gage's initial survival would have ensured him a measure of celebrity, but his name was etched into history by observations made by John Martyn Harlow, the doctor who treated him for a few months afterward. Gage's friends found him"no longer Gage," Harlow wrote. The balance between his "intellectual faculties and animal propensities" seemed gone. He could not stick to plans, uttered "the grossest profanity" and showed "little deference for his fellows." The railroad-construction company that employed him, which had thought him a model foreman, refused to take him back. So Gage went to work at a stable in New Hampshire, drove coaches in Chile and eventually joined relatives in San Francisco, where he died in May 1860, at age 36, after a series of seizures.
In time, Gage became the most famous patient in the annals of neuroscience, because his case was the first to suggest a link between brain trauma and personality change. In his book An Odd Kind of Fame: Stories of Phineas Gage, the University of Melbourne's Malcolm Macmillan writes that two-thirds of introductory psychology textbooks mention Gage. Even today, his skull, the tamping iron and a mask of his face made while he was alive are the most sought-out items at the Warren Anatomical Museum on the Harvard Medical School campus.
Michael Spurlock, a database administrator in Missoula, Montana, happened upon the Wilgus daguerreotype on Flickr in December 2008. As soon as he saw the object the one-eyed man held, Spurlock knew it was not a harpoon. Too short. No wooden shaft. It looked more like a tamping iron, he thought. Instantly, a name popped into his head: Phineas Gage. Spurlock knew the Gage story well enough to know that any photograph of him would be the first to come to light. He knew enough, too, to be intrigued by Gage's appearance, if it was Gage. Over the years, accounts of his changed character had gone far beyond Harlow's observations, Macmillan says, turning him into an ill-tempered, shiftless drunk. But the man in the Flickr photogragh seemed well-dressed and confident.
Subscribe now for more of Smithsonian's coverage on history, science and nature.
Related topics: Photography American History Medicine Late 19th Century
Comments (23) |
i love phineas, he was my great grandfather
Posted by owain the great on September 19,2013 | 04:02 AM
i think that phineas was an inspiration, and that's why i watch phineas and pherb. please reply to this. thanks.xxxxxx
Posted by Owain Ellis on September 18,2013 | 04:25 AM
Wow!! Phineas Gage survived a brain injury. Did you guys know that when you have an open brain injury, the staph and strep bacteria can get it there and create an infection. When the immune system kicks up, it tries to fight off the bacteria, but while it's doing that, the bacteria spiils out toxic bacteria that can infect it, worse than you can imagine it. Your brain is the size of half of a large walnut. :)
Posted by Jessica on May 12,2013 | 07:36 PM
A similar case ocourred last 08/16/2012 in Brazil. See the news here: http://g1.globo.com/rio-de-janeiro/noticia/2012/08/operario-com-vergalhao-no-cranio-e-internado-em-cti-de-hospital-do-rio.html
Posted by Levi de Paula Tavares on August 25,2012 | 12:52 PM
Hi, I'm Cameron from BRMS. This passage i've just read was very interesting. Thank you this helps my paper.
Posted by Cameron Alex Smith on February 28,2012 | 09:41 PM
This story shows that the presant ideas of fine-grained,ocult personality changesdetermined by minute vatiations in brain damage have not been created from whole cloth.indeed Gage's brain was damaged in a certain way( viz, the way it was) and he did suffer a change in personality, but even at the time( as the story discloses) the nature of the change and the correlation with the details of the damage was exagerated.
Posted by Joe Fisher on June 22,2011 | 04:45 PM
omg ican't believe this is real. this tragic accident has me really engaged in this story. this is good to teach to aa science class if any one is studying neurological science or learning it shoul read this!
Posted by KM on June 15,2011 | 08:15 PM
To: Smithsonian Magazine Editors,
From: Mark D. Mooney - firstname.lastname@example.com
Granada Hills, CA 91344
I have been following the story of Phineas Gage and his tragic accident with great interest. In the March (letters) issue there was more interest about Phineas and the photographs. Back in the early 1960's my Dad subscribed to both 'True' and 'Argosy' magazines and as I read about everything I could get my hands on. I read them cover to cover and seeing how I was a fan of the pulp genre anyway I found those magazines would really take me away.
There was a fascinating story in one of them about Phineas Gage. He was working for a railroad, drilling holes and setting off explosives, (black power). In tamping down some in a bore-hole with a steel star drill. It struck off the explosive black powder and drove the star drill through his skull. Somehow he survived the driving of a steel rod through his head. It went though the frontal lobes of his brain and gave him the equivalent of a frontal lobotomy. They went on in the article about his personality changing but they, at the time, didn't know what had changed about him, other than him getting a steel rod driven through his skull.
Let m know if you uncover any more on this fascinating story of struggle and survival.
Sincerely, Mark D. Mooney
Posted by Mark D. Mooney on February 23,2010 | 06:26 PM
Prof. Macmillan and I were thrilled to learn that a distant relative of Phineas Gage, reading Mr. Twomey's story (above) in January's Smithsonian, wrote to the magazine with the news that she too has a portrait of Phineas. The second portrait is discussed in the March "Letters" section
and the new portrait itself may be seen at
Posted by Matthew L Lena (Boston) on February 19,2010 | 10:34 AM
"Your web-site states the information, but thought those of your subscribing public without computers would enjoy this information to "Find Phineas" as well !"
That was one of the funniest things I've read in a long time. Thank you, Mr. Skuba.
Posted by M Carrol on January 24,2010 | 01:06 PM
Uncovered a portrait of the younger Phineas Gage?
It's on you to decide if the picture on this site may be attributed to the younger Phineas Gage. Please consult
Posted by Roberto Casagrande on January 18,2010 | 11:15 AM
can you tell me the summary of this article
Posted by THALIA on January 16,2010 | 01:45 PM
Mr. Duddy: It's always nice to have independent mutually-reinforcing sources of confirmation, and Sherlock Holmes (who comments on the distinctiveness of ears in "The Cardboard Box") would be mightily pleased by your observation.
But the near-certainty that the the Wilgus daguerreotype really does depict Phineas Gage can be established via less exotic considerations. First, we have the writing on the tamping iron seen in the photo, which matches exactly the writing seen on the iron itself (preserved in the Harvard Medical School's Warren Anatomical Museum).
"But," the doubter may say, "this doesn't rule out this being some 19th-century Harvard student who borrowed the tamping iron for an elaborate photographic prank." Well then, consider also the scars and other disfigurements seen in the image, which even on minute examination (daguerreotypes being renowned for their exquisitely fine detail) precisely correspond to the injuries preserved in a ca.-1850 life mask of Gage (also in the Warren) -- *that* would be have been very hard to fake.
Posted by Matthew L. Lena (Boston) on January 13,2010 | 12:37 PM
There is no doubt that the photo is of Gage. Compare his left ear in his photo with the left ear in the photo of the life mask. They are identical.
Since the shape of a person's ears are as unique as fingerprints, this is proof that the photo is indeed that of Gage.
Posted by Thomas Duddy on January 9,2010 | 12:25 PM

subset: commoncrawl


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(£98 per person per week. The rent is inclusive of all bills!) Student accommodation for September 2014.Located in Polsloe Road in close proximity to Peninsula Medical School, St Lukes campus, local amenities and the city centre. A fully furnished, Nine bedroom, period semi-detached, bay fronted pro More details ›
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New York closed Thursday at $1,637.10 and slipped in Asia and London to $1,633 ahead of London's opening. The euro was slightly stronger at €1: $1.3141. Gold Fixed it at $1,629.50 down $13 and in the euro at €1,240.201 down €11.5, while the euro stood at €1: $1.31239. Ahead of New York's opening it stood at $1,628.25 and in the euro €1,239.95 while the euro was at €1: $1.3131. Silver was$30.19 at the close in New York but opened in London at $30.19. Ahead of New York's opening it stood at $29.81.
Gold (very short-term)
Gold's trading range today could go either way without giving clear direction, today in New York.
Silver (very short-term)
Silver's trading range could go either way without giving clear direction, in New York today.
Price Drivers
Another down day for gold as traders feel a soft tone in gold and silver prices.
On the silver price its falls have been greater than we have seen in the gold price, as it breaks down through the $30 level. Is this a reflection of its industrial demand? No. Its price is driven by traders and investors in the Silver Trust. Traders are by far the greatest influence over the price and they have a rock solid belief that silver should move with the gold price. The recent past has shown silver to have much more resilience on the downside movements than gold and to display much more vigor on the upside.
Bear in mind that the industrial applications for silver have moved from a focus on discretionary spending that photography represented to more needed applications in the electronic and medical fields. This makes such demand more robust in a downturn. We don't see this demand diminishing in the near future.
Will it collapse if gold drops? No, we think not. Asian investment demand has grown as the gold price has risen because silver is an alternative to gold there and more affordable to a much wider, poorer market. However, it will be still be driven by traders in the short-term and its price will reflect day-to-day sentiment.
Traders have managed to link the gold price to the state of the U.S. economy and will continue to do so for the immediate future.
[To follow our weekly commentary, please subscribe to our newsletters at www.GoldForecaster.com and at www.SilverForecaster.com.]
Julian D.W. Phillips for the Gold & Silver Forecasters
Global Gold Price (1 ounce)
1 day ago


text:
I would like to remove modem-manager service from my boot, how can I do it ?
Tell me more
Ask Ubuntu is a question and answer site for Ubuntu users and developers. It's 100% free, no registration required.
This it looks to work fine:
Instead this doesn't work ( don't know y ):
| ||||
The simplest way is to:
Works fine in 12.04 LTS. Nothing in my system had dependencies on modemmanager. Or you could search for "modemmanager" in the Ubuntu Software Center and remove it from there (the title is "D-Bus service for managing modems"). | |||||||||||||
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text:
By Mayo Clinic staffCommon heart attack symptoms include:
- Pressure, tightness, pain, or a squeezing or aching sensation in your chest or arms that may spread to your neck, jaw or back)
- A feeling of fullness, nausea, indigestion, heartburn or abdominal pain
- Shortness of breath
- Sweating or a cold sweat
- Feelings of anxiety or an impending sense of doom
- Fatigue
- Trouble sleeping
- Lightheadedness or dizziness
Heart attack symptoms vary
Not all people who have heart attacks experience the same symptoms or experience them to the same degree. Many heart attacks aren't as dramatic as the ones you've seen on TV. Some people have no symptoms at all, while for others, the first sign may be sudden cardiac arrest. Still, the more signs and symptoms you have, the greater the likelihood that you may be having a heart attack. The severity of heart attack symptoms can vary too. Some people have mild pain, while others experience severe pain.
A heart attack can occur anytime — at work or play, while you're resting, or while you're in motion. Some heart attacks strike suddenly, but many people who experience a heart attack have warning signs and symptoms hours, days or weeks in advance. The earliest warning of a heart attack may be recurrent chest pain (angina) that's triggered by exertion and relieved by rest. Angina is caused by a temporary decrease in blood flow to the heart.
Many people confuse a heart attack with a condition in which your heart suddenly stops (sudden cardiac arrest). Sudden cardiac arrest occurs when an electrical disturbance in your heart disrupts its pumping action and causes blood to stop flowing to the rest of your body. A heart attack can cause cardiac arrest, but it's not the only cause of cardiac arrest.
When to see a doctor
During a heart attack, act immediately. Some people wait too long because they don't recognize the important signs and symptoms. Take these steps:
- Call for emergency medical help. If you suspect you're having a heart attack, don't hesitate. Immediately call 911 or your local emergency number. If you don't have access to emergency medical services, have someone drive you to the nearest hospital. Drive yourself only as a last resort, if there are absolutely no other options. Driving yourself puts you and others at risk if your condition suddenly worsens.
- Take nitroglycerin, if prescribed. If your doctor has prescribed nitroglycerin, take it as instructed while awaiting the arrival of emergency medical personnel.
- Take aspirin, if recommended. If you're concerned about your heart attack risk, ask your doctor if chewing a 162- or 325-milligram (mg) aspirin tablet if you have heart attack symptoms is a good idea. Taking aspirin during a heart attack could reduce the damage to your heart by making your blood less likely to clot. Aspirin can interact with other medications, however, so don't take an aspirin unless your doctor or emergency medical personnel recommend it. Don't delay calling 911 to take an aspirin, though. Call for emergency help first.
What to do if you see someone having a heart attack
If you encounter someone who is unconscious from a presumed heart attack, call for emergency medical help. If you have received training in emergency procedures, begin cardiopulmonary resuscitation (CPR). This helps deliver oxygen to the body and brain.
According to guidelines by the American Heart Association, regardless of whether you've been trained, you should begin CPR with chest compressions. Press down about 2 inches (5 centimeters) on the person's chest for each compression at a rate of about 100 a minute. If you've been trained in CPR, check the person's airway and deliver rescue breaths after every 30 compressions. If you haven't been trained, continue doing only compressions until help arrives.
Sudden cardiac arrest during a heart attack is commonly caused by a deadly heart rhythm in which the heart quivers uselessly (ventricular fibrillation). Without immediate treatment, ventricular fibrillation leads to death. The timely use of an automated external defibrillator (AED), which shocks the heart back into a normal rhythm, can provide emergency treatment before a person having a heart attack reaches the hospital. But, if you're alone, it's important to continue chest compressions. If there's a second person present, that person can look for a nearby AED.
- Heart attack. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/heartattack/printall-index.html. Accessed March 21, 2013.
- Crawford MH, ed. Current Diagnosis & Treatment: Cardiology. 3rd ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=8. Accessed March 22, 2013.
- Field JM, et al. Part 1: Executive summary - 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010;122(suppl):S640.
- Understand your risk of heart attack. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HeartAttack/UnderstandYourRiskofHeartAttack/Understand-Your-Risk-of-Heart-Attack_UCM_002040_Article.jsp. Accessed March 23, 2013.
- O'Gara PT, et al. 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127:529.
- Reeder GS, et al. Overview of the acute management of ST elevation myocardial infarction. http://www.uptodate.com/home. Accessed March 22, 2013.
- Thygesen K, et al. Third universal definition of myocardial infarction. Circulation. 2012;126:2020.
- Stefanini GG, et al. Drug-eluting coronary-artery stents. New England Journal of Medicine. 2013;368:254.
- Alcoholic beverages and cardiovascular disease. American Heart Association. http://www.heart.org/HEARTORG/GettingHealthy/NutritionCenter/Alcoholic-Beverages-and-Cardiovascular-Disease_UCM_305864_Article.jsp. Accessed March 22, 2013.


text:
ARDS is an abbreviation for:
Acute Respiratory Distress Syndrome
Find a translation for ARDS in other languages:
Select another language:
What does ARDS mean?
- adult respiratory distress syndrome, ARDS, wet lung, white lung(noun)
- acute lung injury characterized by coughing and rales; inflammation of the lungs which become stiff and fibrous and cannot exchange oxygen; occurs among persons exposed to irritants such as corrosive chemical vapors or ammonia or chlorine etc.
Use the citation below to add this abbreviation to your bibliography:
"ARDS." Abbreviations.com. STANDS4 LLC, 2013. Web. 12 Dec. 2013. <http://www.abbreviations.com/term/575578>.
ARDS also stands for:
- Action Replay game, for use with Nintendo DS system
- Adult Respiratory Distress Syndrome
- Afghanistan Reconstruction and Development Services
- Analysis of Rotor Dynamic Systems
- Annelacute Respiratory Distress Syndrome
... and 5 more »
Nearby & related abbreviations:
Alternative search:
- Search Acute Respiratory Distress Syndrome on Amazon.com
- Search Acute Respiratory Distress Syndrome on Google


text: The ultimate eco yoga mat! Outstanding support and comfort all in a 100% biodegradable yoga mat. At 72 inches long and 5mm thick, the Kulae tpECOmat™ Plus is four inches longer than a standard yoga mat and has been designed with all styles of yoga in mind. Constructed using closed cell technology (so germs, bacteria + odor cannot penetrate the mat surface) and weighing less than 2.5 pounds, this mat is revolutionary, and is the eco standard of yoga mats.


text:
It seems the Victoria Secret Models may be human after all. This is Karolina Kurkova before and after makeup courtesy of Getty Images. See pics of other before and after here
Listen to 99.5 The River weekdays at the times below, and get points you can use to enter great contests that are only for River VIP Rewards members. | ||
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The Station - Smashing Cancer
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The Fray at The River
Sara Bareilles Brave-LIVE
It seems the Victoria Secret Models may be human after all. This is Karolina Kurkova before and after makeup courtesy of Getty Images. See pics of other before and after here
Here is a free gift you can share with your family & friends. Fun & sentimental at the same time. Happy Holidays...hey I'm on a tight budget!
Holiday's getting you stressed out? Have a blood orange (side note...work on a new name), Oatmeal, Turkey or some of these other foods.
Check out the 10 foods that can releave stress here.
photo: getty images
Gotta love the Grumpy Cat. Even Santa can't make him smile
photo: wireimage
I think this guy is bummed out because he didn't make the 2014 NYC Taxi Driver Calendar.
See who did and order yours now.
Hope you get it in time for Christmas. It's on back order till Monday.
photo: getty images
Our neighbors have pretty good light displays so I don't try to compete. 3 strings of lights & a Santa and I'm good. I always wonder where they put all this stuff the rest of the year.
Check out some of the wildest displays here.
photo: getty images
Here is Lady Gaga's Holiday outfit. I think I'll stick to an ugly sweater how about you? Gaga & Katy Perry's Album release party shows will be on the CW 15 again tonight (12/10)
photo: splash news
Thank you for all of your toy donations at the River 12 Hours of Christmas Toy Drive. Thankfully none of these toys showed up. Can you believe some of these?
See the 20 Worst Toys EVER here. (rated PG 13)
Have you ever been "rich" in your life? Newser says 21% have been. They say you are "rich" if you make 250,000 in household income in a year. More here.
Even some rich people drive "regular people" cars. Check them out here
Not rich yet? Don't forget the Mega Millions drawing is about $350,000,000 tonight. Good luck!


text:
annual exclusion amount
Definition from Nolo's Plain-English Law Dictionary
The amount that anyone can give to any recipient, free of federal gift tax, in any calendar year. The amount is indexed for inflation and is adjusted by the IRS each year, in $1,000 increments.
Definition provided by Nolo's Plain-English Law Dictionary.
August 19, 2010, 5:11 pm


text:
We were married at Santos 3 weeks ago on the 12th October. Everything was perfect, from start to finish, all down to the wonderful Santo and his team. His attention to detail and 'nothing too much trouble' attitude, made our special day go so perfect. The food was exceptional as was the service. The courtyard where we married, was the... More
- Also Known As:
- Santo's Higham Farm Hotel Derbyshire
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- TripAdvisor is proud to partner with Booking.com and Priceline so you can book your Santo's Higham Farm Hotel reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.


text:
]Stone Fox wrote: I haven't a clue what I'm supposed to be doing.
Driftingalong wrote:Maybe we could start a SurfingWaves clubhouse thingy?
Surfer Babe of the Day RELATED: General Chat Author: gulfsurfer Replies: 2161 |
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RVCA Craisly Boardshorts in Multi |
RVCA Quadro Boardshort in Ocean Blue |
RVCA Eastern Boardshort in Dirt Teal/Henna |
About Boardshorts
Going on a surf trip? Chasing that next swell? Check out our selection of boardshorts. If you're looking for super stretch, wild colors or even a classic cut, find it here online.


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Domain: Just what you're looking for
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The Ultimate Lifestyle!
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The project was established in 2002 under the leadership of CAMPFIRE which mobilised the Mayambara community and collaborated with the local council. The main role of the community was to conserve all natural resources encompassed on the site.
Accommodation: Five lodges are under construction all at the roof level.
Activities: Nature walks, picnicking, village tours, boating and fishing
Amenities: Reception, restaurant at roof level, borehole sunk with water pump and pipes already connected. A water storage stand made of steel in place to cater for large water tanks. Electric transformer and the cables had also been connected to the 5 site. A durawall and fence surrounds the site.
Challenges: Progress in construction has stalled since the death of the business partner. There is poor security on the site and the water pump, electricity transformer, main gate, door frames and window frames have all been vandalized. Facility is in need of a new investor. Destruction of vegetation in and around the site is rampant – limited resource and organisational capacity of leadership and Trustees to keep degradation under check.
Future prospects: Secure business partner to recapitalise the project and complete construction. There is potential for the development of a jetty at the river to cater for some water related activities such as boating and fishing.
Established in 1998 by the CAMPFIRE programme, the facility is located in Hurungwe District, on the boarders with Gokwe District, on the shores of Sanyati river just after the confluence of the Chiroti and Sanyati Rivers. It is 71 km from Hurungwe along Bumi hills road.
Management of the facility: The project constitutes of four villages of 2400 households and two representatives from each village constitute the ward committee, chaired by the councilor. The resource monitors also seat in the committee which has seven members. For a number of years the facility was managed in partnership with a private operator who conducted both hunting and photographic safaris. From 2010, the operator withdrew and the community is now wholly responsible for managing the camp. The camp staff is made up of six workers, camp attendant and 4 resource monitors. The Hurungwe RDC Natural Resources officer is also responsible for overseeing the management of the site.
Accommodation – Sanyati bridge camp has camping facilities and 4 self catering chalets (round thatched huts).
Access – Accessible by road, 71km from Hurungwe RDC on the Bumi Hills Road. Needs rough terrain road.
Amenities – Mobile telephone network coverage, no electricity on the camp. There is a kiosk at the site, which normally offers cold beers, soft drinks, cigarettes and other smaller things. The kiosk is currently not functional.
Attractions - the camp offers visitors attraction in the form of a variety of wild animals and birds. Sanyati River itself has attractive gorges namely, Mahwindo and Manyenyedzi. The buffer zone offers beautiful scenery from the green vegetation.
Activities – Tourist can also enjoy fishing, camping, canoeing, safari hunting and 4x4 game drives
Awareness – Appears on the CAMPFIRE and STEP Websites and also promoted by the Hurungwe RDC.
Main Challenges: The facility dilapidated after an operator Hurungwe safaris withdrew operations from the facility. The project used to be assisted by CAMPFIRE and Hurungwe RDC for its marketing and promotion of the attraction especially when it was used as a base camp for hunting safaris. From the interview it was noted that the community lacks management skills which is the core for any successful business. Future Prospects: The facility requires a number of renovations noted as follows:
The Last Destination center is situated at the Chiunye Village in Chiunye Ward some 30km from Kotwa Growth Point in the Western direction. Kotwa Growth Point is in Mudzi District some 200km from Harare along Nyamapanda Highway. The project represents one of the best and live culture preservation sites in Zimbabwe that survived the last 10 years of economic decline. Preservation of culture is done through the collection and production of traditional artifacts (wooded, pottery and basketry), maintaining live traditional homestead that show cases day to day lives in a rural homestead, performing traditional dances to visitors and holding traditional ceremonies amidst the charm of well preserved natural environment. The project was designed to benefit 200 individuals in the village. Management of the facility: The facility is managed by a Board drawn from the Chiunye village of 20 households. Day to day management and service provision to visitors is by volunteers from the Chiunye family.
Accommodation – Two roundavels and a camping site can accommodate over 20 visitors within the facility.
Access: The site is accessible by road, 25km off the main Mutoko highway is well maintained gravel road. The highway is well serviced by public transport and visitors will need to organize transport between main road to the site. Amenities – Facility is serviced by mobile telephone network. Other amenities (shops, medical services, curios) are available from Kotwa business center, 30km from the facility.
Attractions: This is a cultural and historical village offering fascinating samples of historical battle fields, homesteads , graveyards, and a hunting area featuring Binga village, traditional foods ,wild fruits, traditional artwork and culturally inclined crafts.
Activities –Cultural dances, music experiences, annual bira (cultural festival) for Chiunye village, demonstrations of traditional rituals that used to be conducted long ago in the event of drought, illness, death and burials.
Awareness – Facility is not actively marketed. Mostly patronized by private schools and culture enthusiasts.
Main Challenges: Limited wider community buy in and ownership, political conflicts, facility needs repairs, a number of restoral projects have not been completed, communities harvest firewood and forest resources in the 10hac facility; poor marketing strategy. Some of the constraints include political tensions in the area, poor marketing and thinning clientele, disintegrating cultural artifacts that need refurbishment. The facility is not registered with Zimbabwe Tourism Authority.
Future Prospects: reconstruction of some of the sites that have been destroyed by harsh weather or stray animals, construction of overnight facilities and crafts center. At the moment the project requires funds to renovate the village and training the members in proper business management. Exploring partnership with Mudzi hotel to access more clientele.
Zimbabwe is a song which, once heard, is never forgotten; a mood to suit the needs of any soul, any time; a spell that binds all those who know her. Her voice brings forth many melodies. Welcome to Zimbabwe, a land rich in diversity ranging from low-lying semi-desert to lush highlands strewn with forests and lakes. Situated on a high plateau in Southern Africa and covering 390 245 Km.
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The Ups and Downs of Using Overlaminates
Overlaminates are becoming more and more widely used to protect images printed on a variety of substrates. Among those overlaminates are architectural finishes that add new life to signs and graphics that once had to stand on their own.
"Many laminates will have UV absorbers which will dissipate those—that harmful exposure of those UV rays. Some people mistakenly call them UV inhibitors, but a UV inhibitor is typically an opaque pigment that will reflect back the light as opposed to something that's clear and will dissipate those harmful UV rays. Laminates do not have UV inhibitors, they have UV absorbers.
"UV inhibitors in laminates provide some additional protection from the degrading effects of light and sun, but not substantial protection; they act more like a sunscreen than a sun block," said Nerenhausen. "The real value of lamination is that it provides rigidity, scratch resistance, a textured surface, and protection from ozone and other pollutants."
Stadelman said, "To many manufacturers it's adding materials to the films to make them last longer outdoors. To MACtac, it's a little bit different. We don't just make the films last a long time outdoors, we add a lot of other UV products to our formulas—whether it's to the film or to the adhesive that's there—to also protect the image; to protect the ink. We've got UV filters or absorbers built in to protect the ink itself."
Matching Materials to the Job
With the wide variety of substrates available, it may not always be easy to choose the correct materials for the job. This can create a number of problems including delamination, failure of the adhesive, and irreparable damage to the final product. Experts claim that the best way to ensure the proper matching of materials to substrates comes through knowledge of the product including the end use plus a strong relationship to the client as well as the vendor.
Stadelman said, "Everything gets an enormous amount of R&D before we ever release it to the market. Typically, a rule of thumb is to try to match media to laminate film. So vinyl goes with vinyl, polyester goes with polyester, etc. I know that's not always possible. For 80 percent of the applications out there, that is the right way to go. Sometimes, though, you need to put polycarbonate to vinyl. When we design our adhesives and our films we make sure that we not only have the right face stock but also an adhesive that helps maintain the same coefficient of expansion and contraction and shrinkage, if possible, so that one doesn't shrink more than the other. Our adhesives are designed to help the media not change dimensionally; to not create failure in the field."
Tony Caruso, Eastern region sales manager of Advanced Greig Laminators Inc. said, "Having a lam that matches the media is important. You can add lam to ink to increase the level of moisture—proof you still need lam to protect the image.
"When people think of laminate they think of plastic, but laminate comes in a variety of materials—hot and cold. Having the right lam is vital to the application. It's important to try to match the laminate with the media."
Caruso goes on to say that AGL is different from its competitors because it uses a different system and way of matching overlaminates to various materials. "We have a match component system that allows us to match the quality of media and laminate. Low melt for the inkjet market, high melt for the offset market. We also add the match component system to our packaging. Our charts show media and description and then match it to the corresponding material."
Bellah said, "Different overlaminates offer varying degrees of optical clarity, conformability, UV protection, chemical resistance, and durability, so matching the material to the job is essential. Both of our overlaminates have a clear, pressure-sensitive adhesive and are applied without heat, are optically clear, and are designed to perform well with our perforated window graphics films. They have important differences, however."
For example, Clear Focus offers two main products that have specific uses and criteria. ClearLam is a 1.5-mil polyester film designed for use on flat surfaces only—e.g., retail store window graphics. It offers UV protection and mark/scuff resistance. CurvaLam is a 2-mil cast PVC film made of high-quality, 100 percent polymeric face stock. CurvaLam mates well with our perforated window films, which are also made of PVC. It's more conformable than ClearLam, which allows it to be used on items that have moderate curves.


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Training & Workshops |
The Faculty Development Center offers training & workshops on a variety of topics throughout the academic year. Click on a heading below to find out more about each series or topic.
Web Enhancement with Canvas: Expand Your Classroom
The Faculty Development Center invites faculty members who would like an orientation to enhancing their class with the new Canvas-powered WorldClassRoom to attend our webinar offerings in the month of September, featuring the Expand Your Classroom series. The four-part Expand Your Classroom webinar series is designed to help instructors learn how to use Canvas on every level of the web-enhancement spectrum, from posting a syllabus, to creating and grading assignments, and even facilitating group projects.
Faculty Information Series 2013 - 2014
The Faculty Development Center invites you to attend the Faculty Information Series. In this series of workshops, Webster Faculty members will learn about how to use various campus resources to enhance teaching and learning, support faculty scholarship, and provide student assistance.
Bookmark our Training & Workshops page for a list of the most up-to-date training offerings from the Faculty Development Center, and to see detailed descriptions of each webinar.
For more information or assistance, please contact the Faculty Development Center at email@example.com or call 1-866-963-8243.
- Web Enhancement with Canvas Webinars
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SOURCE HostelBookers
LONDON, September 16, 2013 /PRNewswire/ --
The best way to discover a travel destination is to ask the locals - so HostelBookers, the budget accommodation specialists, have gathered tips and images from US-based bloggers, accommodation owners and tourist boards to inspire travelers to explore the 'real USA'. The initiative, called the United Sharing Adventure, will continue to be built via users' recommendations and has the support of travel resource DiscoverAmerica.com.
An interactive map lets travellers discover locals' secret food, drink, sight-seeing and partying tips, as well as photos for each state. Users are encouraged to add new tips or images to help build the 'real USA' map.
Recommendations include:
Camila Clark, DiscoverAmerica.com director, marketing communications said: "As specialists in the budget accommodation sector, HostelBookers.com are a good fit for promoting the United States as a premier travel destination. Iconic landmarks, action-packed adventure, breath-taking views, dazzling nightlife or total relaxation the USA's diverse landscape allows visitors to discover this land like never before."
Giovanna Gentile, at HostelBookers.com added: "With this initiative we expect people to share their own experiences and to encourage a larger number to travel to or within the USA to find out more."
For more information or to share your own tips and images please go to http://www.hostelbookers.com/united-sharing-adventure/.
About Brand USA
Brand USA is the public-private partnership responsible for promoting the United States as a premier travel destination and communicating U.S. entry/exit policies and procedures. Established by the Travel Promotion Act in 2010, the organization's mission is to increase international visitation to the United States while working in partnership with the travel industry to maximize the economic and social benefits of travel. These benefits include creating jobs essential to the economy and fostering understanding between people and cultures.
For industry or partner information about Brand USA, visit http://www.TheBrandUSA.com. For information about travel to and around the United States, please visit Brand USA's consumer website at http://www.DiscoverAmerica.com.
About HostelBookers
HostelBookers.com is the leading budget accommodation website in the travel industry not to apply a service charge. Based in London, HostelBookers was launched in 2004 and now employs a team of over 120 people.
It has over 20,000 properties available in more than 3,500 locations worldwide and provides customers with a range of accommodation, from hostels, camping and self-catering apartments to guesthouses and budget hotels.
The site is available in 11 languages.
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text: During our Thanksgiving trip to the Outer Banks to our favorite resort in Kill Devil Hills, we stopped by Barefoot Bernie's for lunch. We shared the "Grouper Feet" (Grouper is a classic Miami favorite), Greek salad, beef/vegetable soup and "Pollo Loco" chicken. The grouper was loaded with breading and deep fried - dripping with fat; literally destroying the delicate flavor... More


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- Musician's Friend Best Selection, Price & Service. Guaranteed.
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Need Help? Ask our Experts or call 800-449-9128
Surf's up with this well-dressed concert ukulele.
This MU75BK concert ukulele is the newest addition to the Mitchell line, featuring all-mahogany construction that ensures warm tone and great projection. The brilliant gloss black finish gives it a unique look, while the abalone rosette and purfling further enhance the beauty of this instrument. Case sold separately.
Catch a wave with this ukulele. Order today.
Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


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Guilford College Honored for Community Service
642 Schools Named to Honor Roll
Washington, D.C. – The Corporation for National and Community Service and the U.S. Department of Education today honored the nation's leading colleges and universities, students, and faculty members, and staff for their commitment to bettering their communities through community service and service learning.
Guilford College was admitted to the Honor Roll for its work in Education, Youth development, Hunger, Homelessness and the
immigrant/refugee community.
"Through service, these institutions are creating the next generation of leaders by challenging students to tackle tough issues and create positive impacts in the community," said Robert Velasco, Acting CEO of CNCS. "We applaud the Honor Roll schools, their faculty and students for their commitment to make service a priority in and out of the classroom. Together, service and learning increase civic engagement while fostering social innovation among students, empowering them to solve challenges within their communities."
"Preparing students to participate in our democracy and providing them with opportunities to take on local and global issues in their course work are as central to the mission of education as boosting college completion and closing the achievement gap," said Eduardo Ochoa, the U.S. Department of Education's assistant secretary for postsecondary education. "The Honor Roll schools should be proud of their work to elevate the role of service-learning on their campuses. Galvanizing their students to become involved in projects that address pressing concerns and enrich their academic experience has a lasting impact – both in the communities in which they work and on their own sense of purpose as citizens of the world. I hope we'll see more and more colleges and universities following their lead."
The President's Higher Education Community Service Honor Roll recognizes higher education institutions that reflect the values of exemplary community service and achieve meaningful outcomes in their communities. Inspired by the thousands of college students who traveled across the country to support relief efforts along the Gulf Coast after Hurricane Katrina, the initiative celebrates the transformative power and volunteer spirit that exists within the higher education community.
The Bonner Center at Guilford College has cultivated several community partnerships in Greensboro. Through these partnerships, Guilford students perform over 50,000 hours of service each year Each partnership operates with a Guilford student who serves as the Project Coordinator. The Project Coordinator recruits and supports volunteers and organizes training and reflection opportunities appropriate to each project. Transportation is provided to each of these sites through carpooling or use of the college van. Students have the opportunity to make positive contributions to the wider community and at the same time enjoy a meaningful volunteer experience with other Guilford College students.
Guilford College is located in Greensboro NC, a vibrant multicultural city. There are over 50,000 immigrants and refugees who call Greensboro home and there are over 90 languages spoken in the public schools. By interacting with people from different cultural backgrounds and gaining sensitivity to their ways of life, Guilford College students deepen their academic investigation of western and other traditions. In the process, students are challenged to envision better societies as well as work collectively with others toward mutual benefit. The Guilford College approach strives for dynamic partnerships among all stakeholders involved, including students, non profits agencies, businesses and the community residents. Through these partnerships Guilford College hopes to build relationships of interdependency instead of dependency. Guilford students and the community help each other with immediate needs; encourage one another to value their cultural heritage instead of giving it up, as they build solidarity with each other.
James Shields, Director of the Bonner Center for Community Service and Learning sums up the Guilford College community service experience. "Guilford College students have logged thousands of hours in the immigrant/refugee community, but what's most important are the thousands of smiles and hugs, the self confidence and pride in a child's eyes when they earn a good grade and the sense of accomplishment as an adult immigrant carries on a conversation in English. We treasure these moments and look to strengthen our ties with Greensboro's immigrant community for years to come."


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Sphinx Competition - Summer Education Program
About the Competition
Application Process Repertoire Requirements Scholarship Programs Soloists Artists Alumni Jury Sphinx Symphony Concert and Ticket Info Support the Competition
Each summer, semi-finalists and alumni of the Sphinx Competition receive full scholarships to renowned summer music programs around the country. These represent an invaluable opportunity for our participants to continue developing their skills and network with their peers throughout the summer. We are proud to partner with the following programs:


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Tag Archives: Anna
Sun, Feb 10, 2013 | 16:52 GMT
Anna: Extended Edition announced, new in-game character creepily named The Wife Doll
Psychological horror title Anna is getting an extended edition, Kalypso Media has announced. To promote the edition, a short film for it has been released.
Sat, Sep 22, 2012 | 19:08 BST
Anna – first-person horror title out on Steam, launch trailer released
Anna, the first-person horror adventure which delves into the "darkest depths of the human psyche," has landed on Steam.
Fri, Aug 31, 2012 | 00:42 BST
Horror adventure Anna arrives September 21 through Kalypso
Kalypso has signed Dreampainters' first-person horror adventure, Anna, for digital release on Mac and PC. The psychological thriller is rife with physics puzzles, and challenges the player with uncovering the protagonist's past, while maintaining their sanity and working towards one of three possible endings. It's due on September 21 for $10, and the digital release includes the protgonist's notebook, the soundtrack, and development photos. Check out a few screenshots through the break.


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Magazines on paper may be dying, but they aint dead yet. I am down to five paper subscriptions (from my high of about 50 in the late 90s). Every now and then I check the newsstands and the library looking to see if I am missing something. What are some magazines worth subscribing to on paper? asked Jan 22 at 13:06 Kevin Kelly To answerers of this question: I'd be very curious to know why it's better in paper form than in electronic?
8 months, 4 weeks ago
Sunday New York Times (and the magazines therein), and Atlantic Monthly linkanswered Mar 24 at 17:39 Lindrum |
The New Yorker, The Economist, MAKE, Esquire, Sunset, Sports and Exotic Cars by Hemmings, Scientific American. I also get Scouting magazine because I'm a Scoutmaster, but I confess I don't read it. linkanswered Feb 04 at 08:45 |
YES! Magazine, only comes quarterly, enjoy the solutions orientation, Knit Magazine, American Craft, The Atlantic linkanswered Jan 26 at 08:16 Awatson |
Wired, Road & Track, Hemmings Sports & Exotic Car, Popular Mechanics. I still enjoy dog-earing a page to ref back to, sharing an issue with a friend, and building my collection of HS&EC for garage reference. linkanswered Jan 26 at 07:30 |
Consumer Reports (life subscription), Smithonian (yearly gift from my father but I'd subscribe anyway), Guns & Ammo, American Rifleman (comes with NRA membership), Guns, Woodsmith, QST (ARRL membership (ham radio)). linkanswered Jan 23 at 12:28 |
For general interest: Popular Mechanics. My professional magazines are IEEE Spectrum, Communications of the ACM, IEEE Computer, and ACM Computing Surveys. For personal improvement: the Ensign. linkanswered Jan 23 at 09:59 |


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From chips to cookies and sodas to teas, each month we'll send 7-10 vegan goodies straight to your door.
Next box ships: Dec 16th
You don't have to believe us! Here it is straight from the snacking source:
"Got my #vegancuts October snackbox! :D Oh and there's yummy #redchai #tea that isn't showed in this picture" @vick_001a
"Vegancuts! Ruby likes it. #ferretlife #cute #ilovemyferret" @tiffany_nadine
"My #vegancuts box!!"@msmrgasp
"I get to Brooklyn and Joe surprises me with a #VeganCuts snack box he ordered! Best bf ever." @gabbieraymond
"So fun to explore!" Choosing Raw
"Filled with all kinds of vegan goodies." The Sweet Life
"They curate really fun products, some that haven't even hit the shelves yet!" Eco-Vegan Gal
"When I opened up my box I felt like a little kid on Christmas!" Kayli Wanders
Here's a little taste of brands we've featured:
Each box includes 7-10 vegan products, ranging from sweet treats to savory snacks. Typically over 80% of the products included are gluten free. If you drool over the products we feature in our marketplace, then you'll love what's inside our box. Have a question? Read our snack box FAQs.
These bloggers and media outlets are feelin' the Snack Box:


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Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder
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- How to Read a Study Record
This study, conducted at the NIH and the Mount Sinai School of Medicine, will examine the effectiveness of a substance P or NK1 antagonist study drug known as GR205171 in treating the symptoms of posttraumatic stress disorder (PTSD).
People between 18 and 65 years of age who have been diagnosed with PTSD may be eligible for this study. Participants undergo the following tests and procedures:
Treatment: Patients are tapered off current ineffective medications over 1 to 2 weeks. All participants receive placebo (sugar pill) at the start of the study. At some point within the first 3 weeks of the study, they are then randomly assigned either to take GR205171 or to continue with placebo for the remainder of the 10-week treatment period.
Clinic visits: Patients come to the clinic once a week during treatment. The following procedures are done at various visits.
- Interviews, self report questionnaires and psychiatric rating scales at every visit.
- Physical examination, blood and urine tests. Blood is drawn up to 10 times during the study.
Follow-up visits continue for up to 3 months after the end of the study, during which patients are offered standard clinical treatment.
Condition | Intervention | Phase |
Drug: NK1 Antagoist (GR205171) Procedure: Psychophysiology (Trauma Script) Procedure: Psychophysiology (Verbal Threat) Procedure: Psychophysiology (Fear Conditioning) Procedure: Psychophysiology (Affective Modulation) Procedure: Psychophysiology (Heart rate variability) Procedure: Lumbar Puncture Procedure: 24-hour plasma sampling Procedure: MRI Device: GR205171 |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Double-Blind Primary Purpose: Treatment |
Official Title: | Evaluation of the Efficacy of the NK1 Antagonist GR205171 in Posttraumatic Stress Disorder |
- Changes in CAPS scores. [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
- Able to identify biological markers that predict response to treatment. [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
Estimated Enrollment: | 52 |
Study Start Date: | September 2006 |
Study Completion Date: | June 2009 |
Primary Completion Date: | June 2009 (Final data collection date for primary outcome measure) |
Drug: NK1 Antagoist (GR205171)
Posttraumatic Stress Disorder (PTSD) is a common chronic anxiety disorder that is often debilitating and follows exposure to an overwhelming traumatic event. The burden of PTSD on individuals and society is significant. The majority of PTSD sufferers also meet the diagnostic criteria for several other psychiatric disorders and many attempt suicide. Despite the devastating impact of PTSD on the lives of millions worldwide, little is known about the etiology or pathophysiology of this disorder. Although disruptions in the hypothalamic-pituitary adrenal (HPA) Axis, noradrenergic, serotonergic systems have been proposed as neurobiological substrates in the development of PTSD, the exact underpinnings of the neurobiology of PTSD remain to be fully elucidated.
PTSD is responsive to treatment with selective serotonin reuptake inhibitors, but response rates rarely exceed 60%, and even fewer patients (20%-30%) experience improvement that could be characterized as remission. Thus, there is a clear need to develop novel and improved therapeutics for PTSD. A growing body of preclinical evidence suggests that activation of the Substance P (SP) and its receptor NK1 is anxiogenic and that NK1 antagonists, upon chronic administration, exert significant dampening (albeit complex) effects on the SP-NP system. Furthermore, several stress paradigms are believed to exert many of their deleterious effects on hippocampal structures via enhancement of SP-NK1 system. Overall, excess activity of the SP-NK1 system stands as a prime candidate for involvement in the pathophysiology of anxiety disorders such as PTSD.
In this study, we propose to investigate the potential antianxiety efficacy of the highly specific NK1 antagonist GR205171 in PTSD. Furthermore, we propose to, in a preliminary fashion, longitudinally investigate whether neuroendocrine surrogate markers are predictive of treatment response.
This is an 8-week double-blind placebo-controlled study that will examine the efficacy and safety of an NK1 antagonist in patients with PTSD.
Patients, ages 18 to 65 years with a diagnosis of PTSD, will in this pilot study be randomized to double-blind treatment to receive either the NK1 antagonist, GR205171 (5 mg/day) or placebo for a period of 8 weeks.
Approximately 52 patients will enter the study to obtain 40 subjects who complete the 8 weeks of acute NK1 antagonist treatment.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Subjects may be included in the study only if they meet all of the following criteria:
- Male or female subjects, 18 to 65 years.
- Female subjects of childbearing potential must be using a medically accepted means of contraception.
- Each subject must have a level of understanding sufficient to agree to all required tests and examinations and sign an informed consent document.
- A negative urine toxicology.
- Subjects must fulfill the criteria for PTSD as defined in DSM-IV (309.81), which should be the primary diagnosis. Diagnoses are based on clinical assessment and confirmed by structured diagnostic interview SCID-P.
- Duration of illness of PTSD for at least 3 months.
- Subjects must have an initial score at Visit 1 and Visit 2 of at least 50 on the CAPS for PTSD Studies.
- Subjects must not have a decrease in the total score of CAPS of greater than 25% during washout (between Visits 1 and 2).
Subjects will be excluded from the study for any of the following reasons:
- Presence of psychotic features.
- Participation in a clinical trial of another investigational drug within 1 month (30 days) prior to study entry (Visit 1).
- Female subjects who are either pregnant or nursing.
- Serious, unstable illnesses including hepatic, renal, gastroenterologic, respiratory, cardiovascular (including ischemic heart disease), endocrinologic, neurologic, immunologic, or hematologic disease.
- Subjects with uncorrected hypothyroidism or hyperthyroidism.
- Previous treatment with NK1 receptor antagonist.
- DSM-IV substance abuse or dependence within the past 90 days.
- Treatment with an injectable depot neuroleptic within less than one dosing interval between depot neuroleptic injections prior to Visit 2.
- Treatment with a reversible MAOI, guanethidine, or guanadrel within 1 week or with fluoxetine within 6 weeks prior to Visit 2.
- Treatment with any other concomitant medication with primarily CNS activity.
- Treatment with clozapine or ECT within 12 weeks prior to Visit 2.
- Current diagnosis of schizophrenia or other psychotic disorder, bipolar disorder, other Axis I disorder (except for major depressive disorder, dysthymia and other anxiety disorders that followed exposure to the trauma) as defined in the DSM-IV.
- Patients who are currently at high risk for homicide or suicide, a score greater than 4 on item 10 of the MADRS.
- Current or planned litigation regarding the traumatic event.
Patients will not be allowed to receive structured psychotherapy during the trial.
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | |
Bethesda, Maryland, United States, 20892 | |
United States, New York | |
Mt. Sinai Medical Center | |
New York, New York, United States, 10029-0574 |
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Sanjay J. Matthew, M.D. |
ClinicalTrials.gov Identifier: | NCT00383786 History of Changes |
Obsolete Identifiers: | NCT00211861 |
Other Study ID Numbers: | 060253, 06-M-0253 |
Study First Received: | October 3, 2006 |
Last Updated: | September 16, 2009 |
Health Authority: | United States: Federal Government |
Keywords provided by National Institutes of Health Clinical Center (CC):
PTSD Substance P Treatment Study |
Placebo Controlled Post Traumatic Stress Disorder |
Additional relevant MeSH terms:
Stress Disorders, Post-Traumatic Stress Disorders, Traumatic Anxiety Disorders Mental Disorders Substance P GR 205171 Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action |
Pharmacologic Actions Physiological Effects of Drugs Antiemetics Autonomic Agents Peripheral Nervous System Agents Central Nervous System Agents Therapeutic Uses Gastrointestinal Agents |
ClinicalTrials.gov processed this record on December 10, 2013


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Glengarry Glen Ross details
Formats: | 15 DVD, Blu-ray |
Starring: | Al Pacino, Jonathan Pryce, Alan Arkin, Bruce Altman, Alec Baldwin, Ed Harris, Kevin Spacey, Jack Lemmon |
Director: | James Foley |
Genre: | Drama |
Studio: | ITV STUDIOS HOME ENTERTAINMENT |
Name | Discs | |
Glengarry Glen Ross |
15 Feature |
DVD Information
Run time: | 1 hour 36 minutes |
Rental release: | 14 Apr 2003 |
Main languages: | English |
Most helpful review
One again Pacino proves his pedigree.
By younglochinvar (66 reviews) from Prestatyn , 26 Sep 2007[Highly rated reviewer]
Probably the best cast ever assembled on the big screen. And it most certainly delivers. Al Pacino should have won the best actor Oscar for which he was nominated and was outshone only by an incredible performance from the great Jack Lemmon.- Was this review helpful to you?
- (33) Yes |
- No (9)
All reviews
(148)It's a great PLAY, on film
By vputz (2 reviews) , 12 Dec 2013Very good, BUT you should know what you're getting. This is an unpleasant play about unpleasant people, executed wonderfully. It even 'feels' like a play with extended sets, rather than a movie. There is a great deal of foul language (evidently the cast would jokingly refer to it as 'death of a f'ing salesman'). Still, good performances and a few scenes and characters that have become 'classics of western pop culture' (Alec Baldwin's 'coffee is for closers' speech, Jack Lemmon's character who was the inspiration for the Gil Gunderson character in the Simpsons, etc). Good play.- Was this review helpful to you?
- (1) Yes |
- No (0)
You'll either love it or hate it
By DjDanny32 (6 reviews) from Luton , 08 Oct 2013All very clever, great cast, and all that arty stuff etc. but I got tired of hearing the f-word again and again and again and again... and again... Gave up after an hour.- Was this review helpful to you?
- (0) Yes |
- No (1)
By Burnhamite (407 reviews) from BURNHAM , 09 Apr 2013Nothing else but a rant between individuals which becomes long and boring in the extreme. Human nature at it's worst and not worth commenting upon,- Was this review helpful to you?
- (0) Yes |
- No (5)
Unpleasant and exhausting rant
By The KnightWatcher (629 reviews) from Gloucestershire , 11 Mar 2013Star studded cast, but very much a stage play style. All acted in a play style single office. I did not enjoy this. A rather pointless flog of a high pressure sales team under enormous pressure themselves. A long aggressive and highly alpha male competitive uncaring rant between the players who spend the entire film insulting and belittling each other.- Was this review helpful to you?
- (0) Yes |
- No (3)
Huge Disappointment
By a customer , 15 Feb 2013Gave up on watching this after persevering for more than half an hour. Found the characters too thoroughly unattractive to stick it out any longer. Maybe the stellar cast were just too good at playing such unpleasant people. Could help to explain the crash of the US property market which triggered the global economic crisis, I suppose.- Was this review helpful to you?
- (0) Yes |
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adidas SLVR
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- Modeled in size M. See fit guide for model's dimensions.
- Revolve Style No. ASLV-MS9
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Maroon |
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THE LOYOLA MAROON APRIL 29, 1988 VOLUME 66, NO. 25 LOYOLA UNIVERSITY, NEW ORLEANS, LOUISIANA 70118 Cotton criticizes hiring procedures By Andrew Nolan Staff writer Dr. William Cotton, associate professor of English, severely criticized Loyola's hiring procedures at the College Assembly for Arts and Sciences on Tuesday.Cotton questioned the decision of a search committee in the hiring of a fulltime professor of Greek and Latin studies, saying he had found 21 irregularities in the process. Cotton criticized the university for failing to evaluate teachers in a classroom atmosphere before making a decision on whether to hire them. Dr. William W. Eidson, dean of Arts and Sciences and chair of the assembly, served on the search committee with the Rev. Emmett Bienvenu, S.J., professor emeritus of Greek and Latin studies. Eidson declined to comment because of litigation pending in the matter. Bienvenu, when reached later, also offercdoffercd no comment. Cotton brought up the case of Dr. John Campbell, part-time assistant professor of Greek and Latin studies. The university declined to hire Campbell for a full-time position despite his recommendation by a consultative body, Cotton said. Cotton claimed the committee failed to evaluate properly the quality of Campbell's teaching and the quality of his pub'ishcd work. In addition, Connie Rodriguez, the candidate to whom the university offered the position, is not the most qualified applicant for the position, Cotton charged. The committee failed to properly evaluate Rodriguez's ability in the classroom or her writing, Cotton said. Her leaching experience has been limited mainly to the secondary school level, he added. Cotton proposed adding additional steps to the hiring process to eliminate these shortcomings. HITTING THE BOOKS-Ben Hulin, advertising senior, and Sabrina Perrault, advertising junior, buckle down for the final week of classes before exams. Sondi Galanti, psychology junior, enjoys the beautiful weather while studying Wednesday. Photos by Mary Degnan Greek panel approves affirmative action plan By Geoff Mattie Assistant News Editor The Greek Life Committee voted unanimously to adopt the fourth draft of the Greek Life Plan for Affirmative Action on Monday. The plan says "positive results are expected to be measurable within the next five years with annual revision as necessary.""Positive results on the lowest level will be interacting and working together over the racial barriers," Tara Loomis, committee chairman, said. "At their best level will be a Greek system that reflects ethnic diversity of the Loyola community."The committee consists of two representatives from each fraternity and sorority on campus. "How good the plan is will be seen in how effective a guide it is to effective action," the Rev. Steven C. Rowntree, S.J., associate professor of philosophy, said. "I think we've done a heck of a job, and we ought to pat ourselves on the back for [agreeing on a plan] because we've been dealing with such different attitudes and backgrounds," Loomis said. Loomis said the agreement's purpose will be to help promote racial understanding."It's going to start in the Greek system, but it won't stop there," Loomis Court invalidates run-off The vice president of the Student Government Association will not be elected until Fall 1988, following the Court of Review's decision to invalidate last week's run-off election between Leonard Lewis, law school freshman, and Dartanian Thomas, political science sophomore.This was the third election for vice president and the second to be ruled invalid. All the elections have involved irregularities and all have been met with appeals by candidates. In the run-off, Lewis received 270 votes, and Thomas had 269. Although 547 votes were cast, only 539 students were listed as having voted. The court ruled the election was invalid "because of the narrow margin of victory and eight point discrepancy betwcenbetwcen the actual votes cast and students approved to vote." In additon, the court recommended that the recall election should not take place this semester, but should instead be held in a "timely fashion at the start of the Fall 1988 semester because of the impossibility of conducting a campus-wide election at the present time." "If I lose fair and square, I can accept that, but i want a chance to lose fair and See Cotton/ page 6 See Affirmative Action/ page 6 See Vice President/page 6 ' m a ■^β /With drii issue, The Maroon
Object Description
Title | Maroon |
Masthead | The Maroon Vol. 66 No. 25 |
Publisher | Loyola University (New Orleans, La.) |
Coverage | United States; Louisiana; New Orleans; |
Date | 1988-04-29 |
Type | Text |
Source | Loyola University New Orleans Special Collections & Archives (http://library.loyno.edu/research/speccoll/) New Orleans, LA |
Format | TIFF |
Subject | Loyola University (New Orleans, La.) |
Rights | Digital rights are held by Loyola University New Orleans. Copyright is retained in accordance with U.S. copyright law. |
Creator | Loyola University (New Orleans, La.) |
Relation-Is Part Of | http://www.louisianadigitallibrary.org/cdm/search/collection/LOYOLA_UMN |
Language | en |
Digitized By | BSLW |
Digitized Date | 2012-2013 |
Contact Information | For information or permission to use/publish, contact: mailto:firstname.lastname@example.com |
Rating |
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Browning Commercial Carp Bomb & Light Feeder Combo Fishing Rod
Catalogue Number: 210-2786
Product Details
This Browning commercial carp bomb and light feeder combo offers you a useful fishing rod for match carp fishing. The sections are made out of lightweight carbon fibre to give you a rod that weighs 200g. For comfort, this feeder rod comes with foam rubber handles. This 3m rod is the ideal partner for use with carp bombs or light feeders. The 2 piece rod with 2 ball bearing reel has been designed to offer you a quality fishing experience
back to topProduct specifications
Key Information | |
Type | Carp |
Material | |
Material | Carbon fibre |
Handle Material | Foam rubber |
Features | |
Rod Length (m) | 3 |
Number Of Sections | 3 Piece |
Dimensions | |
Product Height | 10.0 Centimetre |
Product Width | 155.0 Centimetre |
Product Depth | 14.0 Centimetre |
Product Weight | 0.65 Kilogram |
Assembled Height | 10.0 |
Assembled Depth | 14.0 |
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Article |
January 24, 2013
CPA Annual Meeting Feb 21-24 touts big CPG names, great games
Agenda features CPG Town Hall with ConAgra and Florida's Natural; keynote on 'Great Game of Business' and much more.
The Contract Packaging Association (CPA) poses the question: "What risks are you willing to take to succeed in an ever-changing packaging environment?" The association advises its contract packaging members to increase the odds if succeeding by gaining valuable insights.
of Business methods for efficient, profitable business operation and employee involvement. Baker has been lauded as knowledgeable, engaging and someone who does his homework to understand those to whom he presents by executives of organizations including the National Center for Employee Ownership and the Chicago Family Business Council of DePaul University.
View the full agenda here; visit www.contractpackaging.org/annualmeeting for full details or contact CPA's Mary Von Qualen at [email protected] or by phone: (630) 544-5053.Learn about packaging innovation at The Packaging Conference in Orlando, February 3-5, 2014
A "winning edge" theme permeates the agenda for the Contract Packaging Association (CPA) 2013 Annual Meeting, February 21-24, 2013, at the Waldorf Astoria, Naples, FL (pictured). The agenda is designed with knowledge-building sessions, networking with top executives, and meeting time with suppliers to the contract packaging industry. Among the highlights:
- Town Hall Meeting with ConAgra Foods and Florida's Natural Growers. This interactive event will foster knowledge on CPG companies' co-packing strategies that enhance efficiency and profitability. Panelists include: ConAgra Foods' Jon Heussner, director of operations/business and Florida's Natural Growers' Mike McGee, senior contract packaging manager. The panel will me moderated by CPA board member and software CEO Jason Tham of Nulogy.
- Keynote presentation by Steve Baker, vice president of Great Game of Business, Springfield, MO. The presentation promises to impart insights and tools relating to Open-Book Management" and Great Game
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When is the North pole not the North pole? When MMGW propaganda is involved.
Telegraph and BBC geography FAIL: "Row to the Pole" never made it to the "North Pole" – they are 790 miles short
Posted on August 26, 2011 by Anthony Watts
UPDATE: BBC commits the same FAIL. See below.
Hey.. they only missed by about 800 miles. Right on par with the computer models that are perpetuating this hoax.. . .
The Telegraph article says:
No mention of the fact that they aren't even close. The actual North pole is 790 miles away:The successful trip to the Pole, described as the "greatest ocean rows of all time", was only possible because of more seasonal ice-melt in the Arctic that has opened the waters up.
. . .


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Welcome to CowboysZone! Join us! Come on! You know you want to!
You cannot post in the chat room because you have not posted enough in the forums!
Our Forum Veterans service
Discussion in 'Members Zone' started by jobberone, Nov 11, 2011.
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Do some Arkansas supporters want to play coach roulette? Is that it? Keep changing the head coach until one instantly clicks?
Anton Beard, Nick Babb, and Trey Thompson are all scheduled to sign with Arkansas Wednesday and Thursday.
Be on the lookout for the new Basketball Performance Center opening in Summer 2015 @RazorbackMBB @RazorbackWBB #WPS pic.twitter.com/Z3R7w1LPX3
— Mike Waddell (@mikewaddellUA) November 8, 2013
It looks like UA's committing to having this facility opened in about a year and a half. I followed up with Mike Waddell after he tweeted this, asking when construction was set to begin and he replied "Stay Tuned....". But regardless, doubt this is displayed in Bud Walton if it's not going to happen.
This appears to be a picture of the new concourse graphics in Bud Walton Arena, which we've been told have been updated in prep for Friday
News, notes, and other interesting reads from around the web.
1-0, technically. All according to plan.
The Razorbacks held a media day on Thursday to prep for Sunday's Red-White game, which this year is being called "Hog Wild Hoops"
The media picked the Hogs to finish 8th in the SEC this year, but you'd never know it from listening to Anderson.
News, notes and interesting stuff from around the web.
Maui is great, but what exactly is the goal of a basketball non-conference schedule with zero true road games and no Syracuse or Michigan-caliber home games?
Arkansas will begin against California on November 25th, then will play either Syracuse or Minnesota. Chaminade, Baylor, Gonzaga, and Dayton are on the other side of the bracket.
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Friends and family members paid their respects to George B. Coughlin, an investigator for the St. Clair County state's attorney's office, during his funeral Monday at Blessed Sacrament Catholic Church in Belleville.
Coughlin, 83, worked in law enforcement for more than 50 years. He retired as an East St. Louis police officer and went on to work for the St. Clair County state's attorney's office. He also was a member of the Major Case Squad.
"George was such a plain spoken but encouraging guy," St. Clair County State's Attorney Brendan Kelly said. "He devoted his professional life to protecting the public and he devoted his personal life to loving his friends and family. Everyone from the state's attorney's office, past and present, will miss him so much."
Coughlin's cause of death is unknown. He died Thursday at Memorial Hospital in Belleville.
Coughlin is survived by his children: Craig Coughlin of Millstadt, Cass Coughlin of Chicago and Shawn Coughlin of Belleville. He also is survived by his brother Gene Coughlin of Belleville and six grandchildren.
Kurrus Funeral Home in Belleville handled Coughlin's arrangements. Coughlin was buried at Green Mount Catholic Cemetery in Belleville.


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Samoset Resort: Quiet Luxury in Maine
Filed under: Luxury Travel & Hotels
To truly appreciate what this property has to offer, though, you need to walk through the main building, across the golf course and along the water a bit. Or, you can have someone give you a lift in a golf cart, which might be a bit easier.
The Flume Cottage sits apart from the rest of the resort, resulting in seclusion within seclusion. This1,500 square foot cottage, refurbished in 2010, sits right on the water, with a back deck that sports drop-dead views of the breakwater, with its lighthouse at the end. And, you can soak in the sights from the Jacuzzi that's out there. Since the only adjacent action on land is golf, you don't need to worry about the slightest noise intruding on your getaway, except, perhaps, a knock at the door when your meals arrive.