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This guide describes how to use Windows Azure PowerShell cmdlets to create, test, deploy, and a manage Windows Azure service. The scenarios covered include creating Windows Azure services to host applications, running a service in the Windows Azure compute emulator, deploying and updating a cloud service, setting deployment options for a service, and stopping, starting, and removing a service.
For a detailed description of each cmdlet, see the Windows Azure Management Cmdlets.
Windows Azure PowerShell provides a set of command-line tools for using Windows PowerShell to develop and deploy applications for Windows Azure.
Tasks you can accomplish using the cmdlets include:
For installation instructions, see Install and configure Windows Azure PowerShell.
Use the New-AzureServiceProject cmdlet to create the scaffolding for a cloud service for your application.
The following example shows how to create a new cloud service named MyService.
PS C:\app> New-AzureServiceProject -ServiceName MyService
The cmdlet creates a service subdirectory on your local computer, adds service configuration files to the service directory, and changes the focus of the Windows PowerShell command prompt to the new service directory.
After you create the service, you can run any of the following cmdlets from the service directory to configure a web role or worker role for the service.
When your application is deployed as a cloud service in Windows Azure, it runs as one or more roles. A role simply refers to the application files and configuration. You can define one or more roles for your application, each with its own set of application files and its own configuration. A web role is customized for web application programming, while a worker role is intended to support general development and periodic or long-running processes. For more information about service roles, see Overview of Creating a Hosted Service for Windows Azure.
The cmdlets listed above create a role directory that is ready to run code written in the specified language (Node.js or PHP). After creating a role, you can put code in the role directory and run it in the compute emulator with the Start-AzureEmulator cmdlet or publish it to Windows Azure with the Publish-AzureServiceProject cmdlet.
You can run these cmdlets with no parameters to create a single role instance with the name WebRole1 or WorkerRole1. Use the -Name parameter to use a different role name.
For each role in your application, you can specify the number of virtual machines, or role instances, to deploy using the -Instances option.
The following example shows how to use the Add-AzureNodeWebRole cmdlet to create a new web role named MyWebRole that has two instances.
PS C:\app\MyService> Add-AzureNodeWebRole MyWebRole -I 2
The Start-AzureEmulator cmdlet starts the service in the Windows Azure compute emulator and also starts the Windows Azure storage emulator. You can use the compute emulator to test the service locally before you deploy the service to Windows Azure. You can use the storage emulator to test storage locally before your application consumes Windows Azure storage services.
If your application includes a web role, you can use the –Launch parameter to open the web role in a browser.
The following example runs the MyService application in the compute emulator and opens the web role in a browser.
PS C:\app\MyService> Start-AzureEmulator -Launch
After you finish testing an application locally, run the Stop-AzureEmulator cmdlet to stop the Windows Azure compute emulator, as shown below.
The following example shows how to use Stop-AzureEmulator to stop the emulator.
PS C:\app\MyService> Stop-AzureEmulator
You can use the Set-AzureServiceProject cmdlet with the -Location, -Slot, -Subscription and -Storage parameters to set the default deployment location, slot (Staging or Production), Windows Azure subscription, and storage account to use when you deploy a service. The default options apply to an individual service. You can run the cmdlet from anywhere in the service directory.
These options take effect when you next deploy the service (using Publish-AzureServiceProject). If you want to override a default deployment option during a service deployment, you can use a parameter for the Publish-AzureServiceProject cmdlet.
If you have not set a default deployment option and you do not specify a deployment option to use when you publish the service, the service is deployed using the following settings:
In the following example, the default deployment location for the MyService service is set to Southeast Asia:
PS C:\app\MyService> Set-AzureServiceProject -Location "Southeast Asia"
By default a service is published to a production slot, where it is assigned a friendly URL based on the service name (http://MyService.cloudapp.net). If you prefer to deploy the service to a staging slot for testing before you deploy to production, you can set the default deployment slot to Staging.
The following example sets the default deployment slot for the MyService service to Staging.
PS C:\app\MyService> Set-AzureServiceProject -Slot Staging
You only need to set a deployment subscription for a service if you are an administrator for more than one Windows Azure subscription. If you have been assigned as a co-administrator for subscriptions other than your own subscription, use the -Subscription parameter to specify which subscription to use for a service.
The following example sets the ContosoFinanace subscription as the default subscription to use for the MyService service.
PS C:\app\MyService> Set-AzureServiceProject -Subscription Contoso_Finance
When you deploy a new service, by default, a new storage account is created in the deployment location, and the application package and configuration files are copied to the Windows Azure Blob service using that storage account. The new storage account has the same name and location as the service, and it is associated with the subscription that was used to deploy the service.
If you want to use an existing storage account with a service, you can use the -Storage parameter to specify that storage account as the default storage account for service deployments, or you can use the -Storage parameter for Publish-AzureServiceProject to specify the storage account for the current service deployment.
To find out which storage accounts are available for your Windows Azure subscription, run the Get-AzureStorageAccount cmdlet. If you are a co-administrator for more than one subscription, use the -Subscription parameter to specify which subscription to retrieve the storage information for. The cmdlet retrieves the storage account name and access keys for each storage account.
For information about creating, managing, and deleting storage accounts, How to: Manage Storage Accounts for a Windows Azure Subscription.
In the following example, a service co-administrator retrieves storage account information for the subscription with the imported publish settings.
PS C:\ > Get-AzureStorageAccount Account Name: ContosoUS Primary Key: YSAwVSjixHpcsK/IX7cRcqzVVa19YCUEhzndhZMZL9aMmNT2Du1DPiufPDBiJUO7FW4Dcb7tkzw14VoK0EppnA== Secondary Key: OBlsaR6A4untNNwuhHDkWkcI7pKwTEPA9JYO/Jv2m/zERqrtMjUGVpz8xRZ2mTPp5qksu9K2JawAo5rEKDaL+w== Account Name: ContosoAsia Primary Key: OzAqwcrrtHa4/5qUyekSRK1F257PrzQHE+i4TJc38MHDBDNjZesbbftfm5tta2rsNH0SM7DEnlqt9PW70AB1VA== Secondary Key: xjCQHNwgedo/RXMOk1PKqRHiEpox001/H+qgl/OphoKzOoQTzR/FAGGobsf5HgjE35lfPAD0KeApGFv4ga0hhw==
The co-administrator then sets ContosoUS as the default storage account to use for the MyService service, running the cmdlet from the MyService service directory.
PS C:\app\MyService> Set-AzureServiceProject -Storage ContosoUS
When you are ready to deploy your service to Windows Azure, use the Publish-AzureServiceProject cmdlet. When you deploy a new cloud service, Windows Azure performs the following tasks:
Packages the source and configuration files into a service package (.cspkg file).
Creates a new cloud service.
If no storage account is specified, creates a new storage account if needed.
Copies the service package and configuration files to the Windows Azure blob store for the storage account.
Creates the cloud service and deployment using the uploaded service package.
Use the following parameters to specify deployment options for the current deployment.
The service name must be unique within Windows Azure. If the name you gave the service when you created it is not unique, you can use the -Name parameter to assign a new name.
In the following example, the service name is changed to MyService01 when the service is deployed. The name of the service directory does not change, but the service will be known in Windows Azure as MyService01.
PS C:\app\MyService> Publish-AzureServiceProject -ServiceName MyService01
If you specify a service name that is not unique in Windows Azure, the service deployment fails, and you will see the following error: "Publish-AzureServiceProject : The remote server returned an unexpected response: (409) Conflict."
You only need to use the -Subscription parameter if you are an administrator for more than one Windows Azure subscription. In that case, it is recommended that you include this parameter to ensure that you use the intended subscription with the service.
In the following example, the Contoso_Finance subscription is used to deploy the MyService service.
PS C:\app\MyService> Publish-AzureServiceProject -Subscription Contoso_Finance
Use the -Location parameter to specify a geographic region for the service deployment. If you have not set a default deployment location for the service, and you do not specify a location using this parameter, the service is assigned randomly to either to North Central US or South Central US.
To get a list of available locations, run the following cmdlet.
Help Publish-AzureServiceProject -Parameter Location
In the following example, the Publish-AzureServiceProject cmdlet is used to deploy the service to the Southeast Asia data center:
PS C:\app\MyService> Publish-AzureServiceProject -Location "Southeast Asia"
If you manage multiple services in the same location, you can include the -StorageAccountName parameter to assign an existing storage account in that location instead of creating a new storage account for the service. If you have not specified a default storage account for the service, and you do not specify a service account when you deploy the service, a new storage account is created, even if an existing storage account is available in that location. For information about creating and managing storage accounts, see How to: Manage Storage Accounts for a Windows Azure Subscription.
In the following example, the MyService service is deployed using the StorageUS storage account for the ContosoFinance subscription.
PS C:\app\MyService> Publish-AzureServiceProject -Subscription ContosoFinance -StorageAccountName StorageUS
Use the -Slot parameter to specify whether to deploy the service to the staging environment or the production environment in Windows Azure. By default, services are deployed to production. In Windows Azure, the staging and production environments are distinguished by the address that is used to access the service. Use the staging environment to test a service before deploying it to production, where a friendlier URL is assigned:
Staging URL format: <ServiceID>.cloudapp.net Example: http://b8f3dd0c084a4add81e1c3345eb0af87.cloudapp.net/
Production URL format: <ServiceName>.cloudapp.net Example: http://MyService.cloudapp.net
In the following example, the MyService service is deployed to the Windows Azure staging environment.
PS C:\app\MyService> Publish-AzureServiceProject -Slot Staging
For more information about managing staging and production deployments, see Overview of Managing Deployments in Windows Azure.
If the service contains a web role, you can include the -Launch parameter to open the web role in a browser. All services are started automatically after they are deployed, but the web role is not opened unless the -Launch parameter is included.
In the following example, the MyService service is deployed using values that have been set previously. A new storage account is created. The service is deployed to the production environment.
PS C:\app\MyService> Publish-AzureServiceProject Publishing to Windows Azure. This may take several minutes... 6:15:58 PM - Preparing deployment for MyService with Subscription ID: 0807028c-e0a5-4773-82e3-8cae71dd5702... 6:16:04 PM - Connecting... 6:16:07 PM - Creating... 6:16:09 PM - Created hosted service 'MyService'. 6:16:09 PM - Verifying storage account 'myservice'... 6:18:14 PM - Uploading Package... 6:20:41 PM - Created Deployment ID: 7ce799c2023a4ae9b346b970045cd14c. 6:20:41 PM - Starting... 6:20:41 PM - Initializing... 6:20:55 PM - Instance WebRole1_IN_0 of role WebRole1 is creating the virtual machine. 6:24:26 PM - Instance WebRole1_IN_0 of role WebRole1 is busy. 6:25:42 PM - Instance WebRole1_IN_0 of role WebRole1 is ready. 6:25:43 PM - Created Website URL: http://MyService.cloudapp.net. 6:25:43 PM - Complete.
In the following example, parameters are used to set the subscription (ContosoFinance), slot (Staging), and location (North Central US) for the current service deployment.
PS C:\app\MyService> Publish-AzureServiceProject -Subscription ContosoFinance -Sl staging -L "North Central US"
When you use Publish-AzureServiceProject on a deployed service, the service is either updated in place or a new deployment is created. The update method depends on the types of changes that you make.
The following types of update are performed in place, without redeploying the service:
Adding a new web role or worker role to the service, or changing the number of instances of an existing role.
Updating the application or the service configuration file.
Enabling or disabling remote access to service role instances.
The following types of update initiate a new service deployment:
If you change the subscription, storage account, or deployment location, a new service deployment occurs, and the previous deployment is deleted.
If you change the deployment slot - for example, you deploy a service that is in the staging environment to the production environment - a second deployment is performed without deleting the first deployment.
In the following example, the MyService service is updated in place after a second service role instance is added to the MyWebRole service role.
PS C:\app\MyService> Set-AzureServiceProjectRole -RoleName MyWebRole -Instances 2 PS C:\app\MyService> Publish-AzureServiceProject
The following example shows how you would publish a new service deployment to production. If a service deployment exists in staging, both deployments are retained.
PS C:\app\MyService> Publish-AzureServiceProject -Slot Production
In the following example, a service that has been deployed to the Anywhere Europe location is redeployed to North Europe. Because the location is changing, the service is redeployed and the existing deployment is removed. An existing storage account for the North Europe location is used.
PS C:\app\MyService> Publish-AzureServiceProject -Location "North Europe" -StorageAccountName NorthEuropeStore
You can scale a running service out or in by using the Set-AzureRole cmdlet to add or remove instances to a web role or a worker role.
The following example shows how to update the MyService service by changing the number of instances of the MyWebRole web role to two:
PS C:\app\MyService> Set-AzureRole -Service MyService -Slot Production -RoleName MyWebRole -Count 2
Note that the Set-AzureRole cmdlet does not require you to republish the service since it updates the deployed service configuration file.
The Windows Azure PowerShell cmdlets allow you set up a worker role as a dedicated cache, and configure web roles to access the cache using the memcache protocol.
To create a dedicated cache in an existing project, use the Add-AzureCacheWorkerRole cmdlet. The following example adds a role called mycacherole:
PS C:\app\MyService New-AzureCacheWorkerRole -Name mycacherole
You can then configure a web role to access the dedicated cache using the memcache protocol by using the Enable-AzureMemcacheRole cmdlet. The following example configures an existing web role (called mywebrole) to access the dedicated cache (mycacherole):
PS C:\app\MyService Enable-AzureMemcacheRole mywebrole mycacherole
Clients that can use the memcache protocol (such as PHP and Node.js) can then connect to the dedicated cache using the host name localhost_mywebrole (on port 11211 by default). The following examples show example connection code for PHP and Node.js:
$memcache = new Memcache; $memcache->connect('localhost_mywebrole', 11211) or die ("Could not connect");
var mc = require("mc"); var mcclient = new mc.Client('localhost_mywebrole'); mcclient.connect(function() { console.log("Connected to the localhost memcache on port 11211!"); });
For information about Caching pricing, see Pricing Details.
A deployed application, even if it is not running, continues to accrue billable time for your subscription. Therefore, it is important that you remove unwanted deployments from your Windows Azure subscription. You also have the option to stop your service but not remove it. However, if you do not remove the service, you will still accrue charges for the compute units (virtual machines), even if the service is stopped.
Use the Stop-AzureService cmdlet to stop a running, deployed service. If you have deployments in both staging and production, you can use the -Slot parameter to specify which deployment to stop. If you do not specify a slot, both deployments are stopped.
The following example shows how to stop the MyService service.
PS C:\app\MyService> Stop-AzureService
Use the Start-AzureService cmdlet to restart a service that is stopped. For a service with both staging and production deployments, the -Slot parameter specifies which deployment to start. If the -Slot parameter is not included, both deployments are started.
The following example shows how to start the production deployment of the MyService service.
PS C:\app\MyService> Start-AzureService -Slot production
To remove a service, use the Remove-AzureService cmdlet. If a service has associated deployments, this cmdlet will prompt you to delete the deployments.
PS C:\app\MyService> Remove-AzureService -ServiceName MyService
You can bypass the prompt by using the -Force option with the Remove-AzureService cmdlet. The following example shows how to delete all deployments associated with the MyService service, and the service itself.
PS C:\app\MyService> Remove-AzureService -ServiceName MyService -Force
Many of the web site creation and management tasks that you can perform in the Windows Azure Management Portal can be performed using the Windows Azure Powershell cmdlets. The sections below show you how to perform some basic tasks. For a complete list of web site cmdlets, use the help command:
PS C:\MySite> help website
The examples below assume that the root directory of your local site is MySite.
You can create a web site with the New-AzureWebsite command. The following command shows how to create a new site called mysite. The URL for the site will be mysite.azurewebsites.net.
PS C:\MySite> New-AzureWebsite mysite
To create a web site that is Git-enabled, you must have Git installed locally, and the Git executable must be in your Path environment variable. The following example shows you how to create a web site (mysite) that is Git-enabled:
PS C:\MySite> New-AzureWebsite mysite -Git
When you run the command above from a directory that is not a Git repository, you will receive the following message, even though the command was successful: fatal: Not a git repository (or any of the parent directories): .git.
fatal: Not a git repository (or any of the parent directories): .git
If the local directory is not a Git repository, the command will create one for you. After the repository has been created (or if it was a repository to begin with), the command will also create a remote repository (azure) and create a reference to it in your local repository. You can then proceed to add, commit, and push changes to the remote repository:
git add . git commit -m "your commit comments" git push azure master
If you have a local clone of a GitHub repository or if you have a local repository with single remote reference to a GitHub repository, you can use the -Github flag when creating a new web site to enable publishing from GitHub:
PS C:\MySite> New-AzureWebsite mysite -Github
This command will immediately publish content in your GitHub repository. From then on, any changes pushed to the repository will automatically be published.
After you have pushed changes, you can use the Get-AzureWebsiteDeployment cmdlet to get deployment information:
PS C:\MySite> Get-AzureWebsiteDeployment
App settings are key-value pairs that are available to your application at runtime. In ASP.NET web applications, app settings are accessible via the Configuration.AppSettings property and will override settings with the same key defined in the Web.config file. For Node.js and PHP applications, app settings are available as environment variables. The following example shows you how to set a key-value pair:
PS C:\MySite> $settings = @{"myKey" = "myValue"} PS C:\MySite> Set-AzureWebsite -AppSettings $settings
The Windows Azure PowerShell cmdlets allow you to start, stop, or restart a web site with the following commands:
PS C:\MySite> Start-AzureWebsite PS C:\MySite> Stop-AzureWebsite PS C:\MySite> Restart-AzureWebsite
Windows Azure SQL Database is a cloud-based relational database platform built on SQL Server technologies. (For more information, see Introducing Windows Azure SQL Database.) Windows Azure Powershell provides cmdlets that allow you to create, modify, and remove SQL Database servers.
SQL Database servers are not associated with Cloud Service projects. The SQL Database cmdlets shown below do not need to be run from a project directory as in the examples above.
To create a SQL Database server, use the New-AzureSqlDatabaseServer cmdlet. You will need to supply an adminstrator name and login, and a location:
PS C:\> New-AzureSqlDatabaseServer -AdministratorLogin MyLogin -AdministratorLoginPassword MyPassw0rd -Location "North Central US"
Upon successful creation of a new server, you will see output simailar to this:
ServerName Location AdministratorLogin ---------- ---------- ---------- t9qh586619 North Central US MyLogin
To get a list of servers, use the Get-AzureSqlDatabaseServer cmdlet. To update a server, use the Set-AzureSqlDatabaseServer cmdlet.
After creating a server, you will need to create a firewall rule to make it accessible.
To allow connections to a SQL Database server, you must create a firewall rule that specifies a range of IP addresses from which connections are allowed. The following example show how to use the New-AzureSqlDatabaseServerFirewallRule cmdlet to allow connections from IP address between 188.8.131.52 to 22.214.171.124:
PS C:\> New-AzureSqlDatabaseServerFirewallRule –RuleName MyRule -ServerName t9qh586619 -StartIpAddress 220.127.116.11 -EndIpAddress 184.108.40.206
To allow other Windows Azure services to access the server, create a rule that specifies the StartIpAddressand EndIpAddressboth as 0.0.0.0.
To update an existing rule, use the Set-AzureSqlDatabaseServerFirewallRule cmdlet:
PS C:\> Set-AzureSqlDatabaseServerFirewallRule –RuleName MyRule -ServerName t9qh586619 -StartIpAddress 188.8.131.52 -EndIpAddress 220.127.116.11
To get a list of rules for a server, use the Get-AzureSqlDatabaseServerFirewallRule cmdlet:
PS C:\> Get-AzureSqlDatabaseServerFirewallRule -ServerName t9qh586619
To remove a firewall rule, use the Remove-AzureSqlDatabaseFirewallRule cmdlet.
To remove a SQL Database server, use the Remove-AzureSqlDatabaseServer cmdlet, specifying the server name:
PS C:\> Remove-AzureSqlDatabaseServer -ServerName t9qh586619
The command above will require confirmation that you want to delete the specified server. To override this default behavior, use the -Force parameter. Using this parameter will delete the server without requiring confirmation.


text:
You are here
Getting Safe and Sober: Real Tools You Can Use
Publication Types
Publish Date:
Second Edition -- Revised 2008
A practical tool kit for use with women who have substance abuse or chemical dependence problems and who are, or have been, victims of domestic violence, sexual assault or sexual abuse. The kit also can be used to train service providers about the needs of women whose experience includes both substance abuse and victimization.
For Spanish description, see here:
Getting Safe and Sober: Real Tools You Can Use
Alaska Network on Domestic Violence and Sexual Assault
said on 04/12/2011
said on 04/12/2011
posted on 12/06/2013
posted on 11/25/2013
01/06/2014 - 9:00am
01/16/2014 - 2:00pm
02/07/2014 - 8:30am

subset: commoncrawl


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text:
Charles Hoffman
professor of biology
Ph.D., Tufts University, Sackler School
Phone: 617-552-2779
E-mail: email@example.com
Fields of Interest
Glucose sensing, signal transduction, transcriptional regulation in the fission yeast Schizosaccharomyces pombe. S. pombe as a tool to study cyclic nucleotide phosphodiesterases.
Academic Profile
How do eukaryotic cells sense their environment and regulate biological processes in response to environmental signals? To address this question, my lab studies how glucose triggers repression of transcription of the fbp1 gene in the fission yeast Schizosaccharomyces pombe. Depending upon the carbon source in the medium, S. pombe cells regulate fbp1 transcription over a 200-fold range.
Combining classical yeast genetics with molecular biology, we have identified a number of genes required for both repression and derepression of fbp1 transcription. Glucose repression requires the function of nine git genes leading to the activation of protein kinase A (PKA; cAMP-dependent protein kinase). These genes include seven genes required for activation of adenylate cyclase, one gene encoding adenylate cyclase (git2/cyr1), and one gene encoding the catalytic subunit of PKA (pka1/git6). Four of the genes required for adenylate cyclase activation encode alpha, beta, and gamma subunits of a heterotrimeric G protein, the same type of protein that regulates mammalian adenylate cyclase activity, and a seven transmembrane protein that may function as a glucose receptor. We are presently studying the interactions between these proteins and adenylate cyclase. We have also found that both adenylate cyclase and phosphodiesterase activities are regulated to control cAMP signaling. The remaining three git genes, appear to work independently from the G protein. The git1 protein is unique to S. pombe, while git7 and git10 have orthologs in other organisms that have been shown to physically interact and to work in a variety of processes. We are currently studying the roles of these proteins in cAMP signaling, as well as the mechanisms by which they carry out these roles.
We have also made use of the fbp1 reporters and the mutations in the cAMP signaling pathway to develop strains for high throughput screens (HTSs) to identify compounds that inhibit cyclic nucleotide phosphodiesterases (PDEs). PDEs are important drug targets and the compounds we identify could be useful in the treatment of some types of cancer, as well as a large number of inflammatory and neurological diseases and even HIV infection. We have completed HTSs for PDE4, PDE7, PDE8, and PDE11 inhibitors. The compounds identified in these screens are remarkable with respect to their biological activity in mammalian cell-based assays given that they have not yet been subjected to medicinal chemistry to enhance their physiochemical and pharmacokinetic properties. Our strain collection includes strains that express 15 of the 21 mammalian PDE genes (representing 10 of the PDE 11 families), as well as three Trypanosome PDE genes.
The Paparazzi of Pombe
Check out my Photo Album of the First International Fission Yeast Meeting held in Edinburgh in September 1999.
I also have Photo Albums for
the Second International Fission Yeast Meeting held in Kyoto in March 2002,
the First East Coast Regional Fission Yeast Meeting held in Worcester, MA in July 2003,
the Third International Fission Yeast Meeting held in San Diego in August 2004,
the Second East Coast Regional Fission Yeast Meeting held in Miami, FL in November 2005,
and the Fourth International Fission Yeast Meeting held in Copenhagen in June 2007,
along with my Facebook groups for the Copenhagen Pombe 2007, the Fifth International Fission Yeast Meeting Tokyo Pombe 2009, and the Sixth International Fission Yeast Meeting (Boston USA 2011), which also included photo albums from all of the previous international meetings.
If you have any pictures that you would like to add to these albums, please email them to me or directly add pictures to the Facebook groups.
For other pombe informaton on the web, the best place to start is Susan Forsburg's Lab Page.
Representative Publications
Demirbas, D., Wyman, A.R., Shimizu-Albergine, M., Cakici, O., Beavo, J.A., and Hoffman, C.S. (2013). A Yeast-Based High-Throughput Screen Identifies A Phosphodiesterase Inhibitor That Elevates Steroidogenesis In Mouse Leydig Cells Via PDE8 And PDE4 Inhibition. PLoS One. 2013;8(8):e71279. doi: 10.1371/journal.pone.0071279.
Link to abstract: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071279
de Medeiros, A.S., Magee, A., Nelson, K., Friedberg, L., Trocka, K., and Hoffman, C.S. (2013). Use of PKA-mediated phenotypes for genetic and small molecule screens in Schizosaccharomyces pombe. Biochem. Soc. Transactions (in press).
Ceyhan O., Birsoy K., and Hoffman C.S. 2012. Identification of biologically active PDE11-selective inhibitors using a yeast-based high throughput screen, Chemistry & Biology, 19:155-163.
Link to abstract: http://www.ncbi.nlm.nih.gov/pubmed/22284362
Mudge D.K., Hoffman C.A., Lubinski T.J., and Hoffman C.S. 2012. Use of a ura5+-lys7+ cassette to construct unmarked gene knock-ins in Schizosaccharomyces pombe, Current Genetics, 58: 59-64.
Link to abstract: http://www.ncbi.nlm.nih.gov/pubmed/22198627
Didem Demirbas, Ozge Ceyhan, Arlene R. Wyman and Charles S. Hoffman 2011. A Fission Yeast-based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity, Handbook of Experimental Pharmacology (Houslay, Francis, and Conti eds.) Phosphodiesterases as Drug Targets 2011 (204): 135-149.
Link to abstract: http://www.ncbi.nlm.nih.gov/pubmed/21695638
Demirbas, D., Ceyhan, O., Wyman, A.R., Ivey, F.D., Allain, C., Wang, L., Sharuk, M.N., Francis, S.H., and Hoffman, C.S. 2011. Use of a Schizosaccharomyces pombe PKA-repressible reporter to study cGMP-metabolising phosphodiesterases. Cellular Signalling. 23(3):594-601. (link to PubMed abstract).
Ivey, F.D., Taglia, F.X., Yang, F., Lander, M.M., Kelly, D.A., and Hoffman, C.S. 2010. Activated alleles of the Schizosaccharomyces pombe gpa2+ Gα gene identify residues involved in GDP-GTP exchange. Eukaryotic Cell 9: 626–633 (link to PubMed abstract).
Alaamery, M.A., Wyman, A.R., Ivey, F.D., Allain, C., Demirbas, D., Wang, L., Ceyhan, O., and Hoffman, C.S. 2010. New classes of PDE7 inhibitors identified by a fission yeast-based HTS. Journal of Biomolecular Screening 15: 359–367 (link to PubMed abstract).
Roux, A.E., Leroux, A., Alaamery, M.A., Hoffman, C.S., Chartrand, P., Ferbeyre, G., and Rokeach, L.A. 2009. Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast. PLoS Genetics 5(3): e1000408 (link to PubMed abstract).
Hirota, K., Miyoshi, T., Kugou, K., Hoffman, C.S., Shibata, T., and Ohta, K. 2008. Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs. Nature 456: 130–134 (link to PubMed abstract).
Leem, Y.-E., Ripmaster, T., Kelly, F., Ebina, H., Heincelman, M., Zhang, K., Grewal, S.I.S., Hoffman, C. S., and Levin, H. L. 2008. The pol II promoters of Schizosaccharomyces pombe are targeted by an LTR retrotransposon that is capable of repairing the promoters it disrupts. Molecular Cell 30: 98–107 (link to PubMed abstract).
Alaamery, M.A., and Hoffman, C.S. 2008. Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling. Genetics 178: 1927–36 (link to PubMed abstract).
Ivey, F.D., Wang, L., Demirbas, D., Allain, C., Hoffman, C.S. 2008. Development of a fission yeast-based high-throughput screen to identify chemical regulators of cAMP phosphodiesterases. Journal of Biomolecular Screening 13: 62–71 (link to PubMed abstract).
Hoffman, C.S. 2007. Propping up our knowledge of G protein signaling pathways: diverse functions of putative noncanonical Gbeta subunits in fungi. Science's STKE 370: 3 (link to PubMed abstract).
Kao, R.S., Morreale, E., Wang, L., Ivey, F.D., Hoffman, C.S. 2006. Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase. Genetics 173: 49–61 (link to PubMed abstract).
Hoffman, R.L., and Hoffman, C.S. 2006. Cloning the Schizosaccharomyces pombe lys2+ gene and construction of new molecular genetic tools. Current Genetics 49: 414–420 (link to PubMed abstract).
Wang, L., Griffiths, K., Zhang, Y.H., Ivey, F.D., Hoffman, C.S. 2005. Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling. Genetics 171: 1523–1533 (link to PubMed abstract).
Ivey, F.D., and Hoffman, C.S. 2005. Direct activation of fission yeast adenylate cyclase by the Gpa2 Galpha of the glucose signaling pathway. Proceedings of the National Academy of Sciences of the USA 102: 6108–6113 (link to PubMed abstract).
Hoffman, C.S. 2005. Except in every detail: comparing and contrasting G-protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Eukaryotic Cell 4: 495–503.
Hoffman, C.S. 2005. Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombe. Biochemical Society Transactions 33: 257–60 (link to PubMed abstract).
Stiefel, J., Wang L., Kelly, D.A., Janoo, R.T., Seitz, J., Whitehall, S.K., Hoffman, C.S. 2004. Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe. Eukaryotic Cell 3: 610–9 (link to PubMed abstract).
Wang, L., Kao, R., Ivey, F.D., Hoffman, C.S. 2004. Strategies for gene disruptions and plasmid constructions in fission yeast. Methods 33: 199–205 (link to PubMed abstract).
Hirota, K., Hasemi, T., Yamada, T., Mizuno, K.I., Hoffman, C.S., Shibata, T., Ohta, K. 2004. Fission yeast global repressors regulate the specificity of chromatin alteration in response to distinct environmental stresses. Nucleic Acids Research 32: 855–62 (link to PubMed abstract).
Hirota, K., Hoffman, C.S., Shibata, T., Ohta, K. 2003. Fission yeast Tup1-like repressors repress chromatin remodeling at the fbp1+ promoter and the ade6-M26 recombination hotspot. Genetics 165: 505–15 (link to PubMed abstract).
Yang, P., Du, H., Hoffman, C.S., Marcus, S. 2003. The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe. Molecular Genetics and Genomics 269: 116–25 (link to PubMed abstract).
Greenall, A., Hadcroft, A.P., Malakasi, P., Jones, N., Morgan, B.A., Hoffman, C.S., Whitehall, S.K. 2002. Role of fission yeast Tup1-like repressors and Prr1 transcription factor in response to salt stress. Molecular Biology of the Cell 13: 2977–89 (link to PubMed abstract).
Schadick, K., Fourcade, H.M., Boumenot, P., Seitz, J.J., Morrell, J.L., Chang, L., Gould, K.L., Partridge, J.F., Allshire, R.C., Kitagawa, K., Hieter, P., and Hoffman, C.S. 2002. Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgt1p family, is required for glucose and cAMP signaling, cell wall integrity, and septation. Eukaryotic Cell 1: 558–567 (link to PubMed abstract).
Ivey, F.D., and Hoffman, C.S. 2002. Preview: Pseudostructural inhibitors of G protein signaling during development. Developmental Cell 3: 154–155 (link to PubMed abstract).
Kelly, D.A., and Hoffman, C.S. 2002. Gap repair transformation in fission yeast to exchange plasmid selectable markers. Biotechniques 33: 978–982 (link to PubMed abstract).
Takagi, T., Cho, E.-J., Janoo, R.T.K., Polodny, V., Takase, Y., Keogh, M.-C., Woo, S., Fresco-Cohen, L.D., Hoffman, C.S., and Buratowski, S. 2002. Divergent subunit interactions among fungal mRNA 5'-capping machineries. Eukaryotic Cell 1: 448–457 (link to PubMed abstract).
Landry, S., and Hoffman, C.S. 2001. The git5 Gb and git11 Gg form an atypical Gbg dimer acting in the fission yeast glucose/cAMP pathway. Genetics 157: 1159–1168 (link to PubMed abstract).
Janoo, R.T.K., Neely, L.A., Braun, B.R., Whitehall, S.K., and Hoffman, C.S. 2001. Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex. Genetics 157: 1205–1215 (link to PubMed abstract).
Neely, L.A., and Hoffman, C.S. 2000. PKA and MAPK pathways antagonistically regulate fission yeast fbp1 transcription by employing different modes of action at two upstream activation sites. Molecular and Cellular Biology 20: 6426–6434 (link to PubMed abstract).
Welton, R.M., and Hoffman, C.S. 2000. Glucose monitoring in fission yeast via the gpa2 G alpha , the git5 G beta, and the git3 putative glucose receptor. Genetics 156: 513–521 (link to PubMed abstract).
Landry, S., Pettit, M.T., Apolinario, E., and Hoffman, C.S. 2000. The fission yeast git5 gene encodes a Gb subunit required for glucose-triggered adenylate cyclase activation. Genetics 154: 1463–1471 (link to PubMed abstract).
Hoffman, C.S., and Welton, R. 2000. Mutagenesis and gene cloning in Schizosaccharomyces pombe using nonhomologous plasmid integration and rescue. Biotechniques 28: 532–6, 538, 540 (link to PubMed abstract).
Dal Santo, P., Blanchard, B., and Hoffman, C.S. 1996. The Schizosaccharomyces pombe pyp1 protein tyrosine phosphatase negatively regulates nutrient monitoring pathways. Journal of Cell Science 109: 1919–1925 (link to PubMed abstract).
Jin, M., Fujita, M., Culley, B.M., Apolinario, E., Yamamoto, M., Maundrell, K., and Hoffman, C.S. 1995. sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Genetics 140: 457–467 (link to PubMed abstract).
Nocero, M., Isshiki, T., Yamamoto, M., and Hoffman, C.S. 1994. Glucose repression of fbp1 transcription in Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein a subunit encoded by gpa2/git8. Genetics 138: 39–45 (link to PubMed abstract).
Hoffman, C.S., and Winston, F. 1991. Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. Genes and Development 5: 561–571 (link to PubMed abstract).


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John Davies Philip A Dente Lorena Endara Pablo Fernando Bee Flowers Nicola Hulett Peter Marshall
Paul Anthony Melhado Neal Oshima Paul Raphaelson Rabi Rashmi Roy Herman Schartman
Mike Seaborne Luca Tommasi
Herman Schartman Backyards
of Kiev
Pablo Fernando: Shanghais
Visual Interruptions
Philip A Dente: Northeastern Pennsylvania
Paul Anthony Melhado: How We Use Land
Lorena Endara: Panama
Neal Oshima: Squatter Settlements in Metro Manilla
Luca Tommasi: A changing China
Peter Marshall:Thames Gateway
Peter Marshall: Wider London
Mike Seaborne: High Street London
All Photographers on this site
Rabi Rashmi Roy Urbanisation
in India
A new essay on the site:PHOTOGRAPHS OF PLACES AND EXPANDING OUR VISUAL LITERACY: Roger Estop
Gabriele Basilico, one of the best-known of urban landscape photographers, died earlier this month. There are some links to his work and obituaries on >Re:PHOTO.
A new book London Dérives, with pictures taken in London from 1975-83 by Peter Marshall is now available in print or PDF. You can also look at a larger body of work from which it was produced on-line at London Photographs.


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330 results for "norcross"
John Norcross #57 LB
UA Game jersey tour: Lorenzo Carter
Gerry HamiltonFive-star defensive end Lorenzo Carter (Norcross, Ga./Norcross) was presented his honorary game jersey at his high school on Thursday, during the American Family Insurance Selection Tour for the 2014 Under Armour All-America High School Football Game...
Blog | November 01, 2013 -
Video results for "norcross"
Recruiting video for offensive-guard, Britt Lee
September 27, 2013 -
Lorenzo Carter: Blazing New Trails
August 07, 2013 -
Recruiting video for offensive-tackle, Horatio Walker
July 18, 2013 -
Recruiting video for safety, Brandon Garner
June 01, 2013
Harlem Globetrotters acquired by Herschend Family Entertainment C...
Georgia-based Herschend Family Entertainment Corp. has acquired Harlem Globetrotters International Inc. from Shamrock Capital Advisors.
Story | Conversation | October 01, 2013 -
SEC recruiting storylines: Aug. 8
Derek TysonAs we get closer to football season several SEC programs are continuing with their summer momentum and some big names could be on the verge of decisions. Lorenzo Carter announces his top seven Five-star defensive end Lorenzo Carter (Norcross, G...
Blog | August 08, 2013 -
Photo results for "norcross"
BESTPIX Atlanta Tennis Championships - Day 7
July 24, 2011 -
Atlanta Tennis Championships - Day 7
July 24, 2011 -
Atlanta Tennis Championships - Day 7
July 24, 2011 -
Atlanta Tennis Championships - Day 7
July 24, 2011
ESPN 300 LB Mouhon picks Tennessee
Kipp AdamsESPN 300 linebacker Kevin Mouhon (Norcross, Ga., Norcross) became the 24th member of Tennessee's 2014 recruiting class on Sunday. He confirmed in a text message that he committed to the Volunteers. Mouhon, a 6-foot-1, 215-pound prospect, is the No...
Blog | July 21, 2013 -
No rush for five-star DE Carter
Kipp AdamsAnyone that has a good read on where five-star prospect Lorenzo Carter (Norcross, Ga./Norcross) is headed might want to give the No. 10 prospect in the country a heads up. Because he says he has no idea. "People say that because of the people t...
Blog | June 26, 2013 -
ESPN 300 targets: Florida State
Corey DowlarWith the release of the ESPN 300 rankings on Monday, NoleNation takes a look at some targets the Seminoles could be in position to land. 1. ATH Myles Autry (Norcross, Ga./Norcross) 6-foot, 175 pounds ESPN 300 rank: 256 Why they want him: The ...
Blog | June 18, 2013 -
Autry aching to return to the game
Radi NabulsiLAWRENCEVILLE, Ga. -- Myles Autry is still on the sidelines. A vicious injury to his knee last fall, with tears to his ACL, MCL and meniscus, has kept the Norcross (Ga.) High School athlete from participating in basketball, track, spring practice and...
Blog | June 05, 2013 -
DE Carter enjoying the ride this spring
Radi NabulsiNORCROSS, Ga. -- ESPN 150 defensive end Lorenzo Carter seems to never stop grinning, even on the football field. His 100-megawatt smile calls to mind another affable defensive end, Michael Strahan, complete with the trademark gap. Even a shoving matc...
Blog | May 22, 2013 -
Watch List DE Carter attracted to success
Radi NabulsiBUFORD, Ga. -- ESPN Watch List defensive end Lorenzo Carter (Norcross, Ga./Norcross) credits his blindingly pink socks and highlighter yellow shoelaces with helping him win the defensive lineman MVP award at the Atlanta NFTC on Saturday. The award...
Blog | April 16, 2013 -
HoopGurlz -- North Carolina Tar Heels commit Diamond DeShields al...
Andrew LinnehanNorth Carolina commit Diamond DeShields disliked losing so much that it turned her off to basketball for years, but she returned to her first love and built herself into a McDonald's All American.
Story | Conversation | April 02, 2013 -
Tide answer Carter's questions on visit
Greg OstendorfTUSCALOOSA, Ala. -- The majority of Alabama's weekend visitors came up for the day on Saturday to watch practice, but ESPN Watch List defensive end Lorenzo Carter (Norcross, Ga./Norcross) spent the whole weekend in Tuscaloosa with his family. Cart...
Blog | March 18, 2013 -
LB Mouhon talks FSU visit, top five
Kipp AdamsESPN Watch List prospect Kevin Mouhon (Norcross, Ga./Norcross) has seen his recruitment take off since helping his team win the Georgia Class AAAAAA state championship in December. Following a standout performance in the Rising Seniors Junior Bowl, t...
Blog | March 04, 2013 -
ESPN 150 RB Kamara signs with Bama
Kipp AdamsNORCROSS, Ga. -- The rich get richer. ESPN 150 running back Alvin Kamara (Norcross, Ga./Norcross) has been well aware of the running backs on campus at Alabama, as well as the three other ESPN 150 prospects slated to vie for carries in the Crimson...
Blog | February 06, 2013 -
Alvin Kamara: TweetChat
Kipp AdamsRunning back Alvin Kamara (Norcross, Ga./Norcross) will decide between Alabama and Georgia on signing day, announcing his decision at 3:35 p.m. ET on ESPNU. While it was thought that the Bulldogs were the team to beat several times last year, it seem...
Blog | February 05, 2013 -
Watch List LB Mouhon eats up Athens
Radi NabulsiIn the past month, 2014 linebacker Kevin Mouhon (Norcross, Ga./Norcross) has quickly become one of the hottest recruiting targets in the Peach State. The ESPN Watch List junior now has double-digit offers from programs including Florida State, Oh...
Blog | February 05, 2013 -
Watch List athlete Autry likes plan
Radi NabulsiESPN Watch List athlete Myles Autry (Norcross, Ga./Norcross) has close to 20 offers, some as a running back, some as a receiver but most are just as an all-around offensive threat. He plays the slot, runs out of the backfield and even plays quarterb...
Blog | February 03, 2013


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- With Mayo Clinic lactation consultant
Elizabeth LaFleur, R.N.
Labor and delivery (7)
- Doula: Do you need a doula?
- Back labor: Childbirth myth or reality?
- Cord blood banking: What are the options?
- see all in Labor and delivery
Lactation suppression: Can medication help?
Can medication help suppress lactation after childbirth?
from Elizabeth LaFleur, R.N.
Yes — but medication for lactation suppression generally isn't recommended.
Injections of high doses of estrogen were once used to stop milk production. Estrogen injections aren't used today, however, due to a risk of potentially dangerous blood clots.
Similarly, bromocriptine (Parlodel) — a drug that was once used for lactation suppression — is no longer recommended. The drug has been associated with high blood pressure, heart attack and stroke, especially for women who developed high blood pressure during pregnancy.
If breast-feeding isn't possible, it's safest to let milk production diminish naturally. In the meantime, don't stimulate your breasts or express milk.
To relieve breast engorgement and pain — which typically peaks during the first week after delivery — you might:
- Wear a supportive bra
- Apply ice packs to your breasts
- Take over-the-counter pain relievers
Sagging breasts: Inevitable after breast-feeding?
- Oladapo OT, et al. Treatments for suppression of lactation (Review). Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005937.pub3/abstract. Accessed Nov. 6, 2012.
- Papadakis MA, et al. Current Medical Diagnosis & Treatment 2013. 52nd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed Nov. 6, 2012.
- DeCherney AH, et al. Current Diagnosis & Treatment Obstetrics & Gynecology. 10th ed. New York, N.Y.: The McGraw-Hill Companies; 2007. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=9. Accessed Nov. 6, 2012.


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After seeing the bling of Mawi at London Fashion Week I was intrigued to learn they have a Disney collaboration line too, not cheap but more suitable for children but with the same glittering luxe factors of the adults jewellery.
With the classic Mickey and Minnie mouse ear symbols the line has glittering pendants, bauble necklaces with hearts, bracelets and for the older teens stone earrings.
The British based but Indian born Mawi Keivom has celebrity customers such as Emma Watson and Cheryl Cole loving her adult creations, maybe this range will add new up and coming tween starlets to her customer base too.
Disney shots by Mawi – others Smudgetikka – all rights reserved
All posts copyright Smudgetikka – permission must be asked for reproduction 2009 – 2012


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Adams and Reese is the latest Am Law 200 firm to set up shop in South Carolina, announcing Tuesday its combination with 23-lawyer shop Ellis, Lawhorne & Sims in the Palmetto State's capital.
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South Carolina Bound: Adams and Reese Opens in Columbia
The Am Law Daily
May 21, 2013
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In 2005, my girlfriend died in a car accident. Although I only knew her for 18 months or so, this is our story. : Non-Fiction » Read
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Ophelias Bed and Breakfast is a warm, comfortable and beautiful place where guests are treated like family. The hosts are very accomidating and they are both great cooks! My daughter and I have stayed here several times and feel very comfortable and "at home" at Ophelias B and B.
- Official Description (provided by the hotel):
- This 1925 English country Estate sits on three acres surrounded by trees, gardens and a pond. Located on the edge of Tipperary Hill, the Inn is surrounded by parks....an arboretum across the street on one side, a golf course and zoo on the other side and the back side of a nine acre park. Although you feel like you are in the countryside, you are only six minutes from the heart of downtown Syracuse's Armory Square District. Bicyclists not only enjoy the safe keeping of their bikes in the spacious garage, but after a long day can find two outstanding restaurants within walking distance. This hidden gem is a great place to unwind, relax and take in the beauty that surrounds you. We cater to your special dietary needs. Come enjoy our Labor of Love. ... more less


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Tracy (13-2-2 overall, 6-0-2 SJAA) can secure the title with a win in either of its last two home games against Bear Creek on Wednesday, May 2, or Chavez on Friday, May 4.
Coach Nate Perry added that winning both games would make this Bulldogs team to have an undefeated league title in more than 20 years.
Tracy's Bria Outland scored the first two goals with assists from Kaitlyn Crone and Cailie Chayrez. Nicole Gasior scored on an assist from Marissa Sanchez while Kellie Piazza scored two goals, both on free kicks.
Kimball 2, East Union 2
East Union's perfect Valley Oak League season came to an end Wednesday in Manteca as the Jaguars were forced to play with a makeshift lineup.
Coach Ron Hattley had to shuffle the Kimball lineup because of injuries and a recent red card.
Taylor Hopkins scored less than a minute into the match for Kimball after she fired a cross in front of the goal, and Katie Little shot it right back for Hopkins to shoot into the net.
The Jaguars (12-5-2 overall, 4-4-2 VOL) got another chance to score midway through the first half when Mireya Magana crossed the ball from the right into the center of the penalty area for East Union (17-1-3, 11-0-2). Mariah Hinds sprinted up and made a one-touch shot for the goal.
"It was an outstanding example of two attacking players being in sync with one another and reading the same space to create a scoring opportunity," Hattley said.
East Union scored in the 32nd minute and teams went into the half with the Jaguars ahead 2-1.
The Lancers tied it up with a penalty kick midway through the second half.
Hattley said that the pace intensified for the rest of the second half. Kimball's best chance to score again came at the end as Magana fired a shot from the left side and Hopkins was there, but not quite close enough to connect for a shot.
Millennium 3, Big Valley Christian 0
The Millennium soccer team faced off against a stubborn Big Valley Christian team on Tuesday, April 24 at the Tracy Learning Center but eventually broke the game open for a 3-0 win.
Falcon coach Mario Ron said the score didn't reflect the relentless Lions offense that his team (-1-2 overall and 5-1 in the Central California Athletic Alliance) and his goalkeeper Hailey Rockwell faced during the game.
"Hailey saves us so many times in the first half," Ron said. "They were all over us."
It was a 0-0 game at the half, and about 20 minutes into the second half the Falcons broke the stalemate when Summer Escobar headed in a corner kick. Ivy Torres scored two more goals for the Falcons.
St. Mary's 10, West 1
The Rams from St. Mary's High affirmed their place atop the Tri-City Athletic League Standings with a 10-1 win at West High Tuesday, April 24.
St. Mary's (23-1, 7-0 TCAL) scored four goals in the first half before West got on the board.
Sahar Latifi scored West's only goal in a penalty kick in the 38th minute. West's Lilibeth Torres took a shot on the goal, the ball deflected off the crossbar and Kimberly Becerra came in for the followup shot but was fouled inside the box. The St. Mary's player got a yellow card and the Wolf Pack scored on a subsequent penalty kick.
The Rams scored once more in the final minute of the first half for a 5-1 lead. Two more goals were also scored early in the second half, followed by three more goals in a three-minute span.
Tracy resident, Grace Cabri, scored two goals for St. Mary's and also had seven assists, which coach Mark Kusanovich noted was a school record. Regan Porteous and Jamie Flores each scored three, and Carlie Dunning and Stefanie Lucarelli each scored one.
The loss drops West to 1-4-2 in the TCAL.
St. Mary's also won the freshman-sophomore game, 2-0, which puts the West frosh-soph team at 2-3-2 in the TCAL.
Sierra 2, Kimball 1
Kimball High's soccer team fell to fifth place in the Valley Oak League standings with home loss on Monday, April 23.
Sierra (9-5-4, 6-3-2 VOL) had a 1-0 lead at the half on an unassisted goal by Naomi Nunis in the 19th minute. Kimball (11-5-2, 4-4-2 in the VOL) tied it up one minute into the second half when Adaurie Dayak passed to Taylor Hopkins, who scored for the Jaguars.
Sierra got a break in the 66th minute when Sydnee Canales took a long, low shot that deflected off of a Kimball defender and then went over the head of goalkeeper Tayler Lennier — who had four saves on the night.


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The Ripkens don't make the cut?
What about the Herbstreit's? J/king. Happy Fathers Day to all the Pappy's.
"Say my name."
Shawn and Ron Springs would be a nice addition to see also.
Funny that the Earnhardts are included, the poll clearly specifies "sports" history.
Gotta please all types of "sports" fans
Hockey could be considerated a sport north of the border, so my vote must go to da Hull's.
The Mathews family....brothers and sons.
"It's just another case of there you are". ~ Doc (1918-2012)
Why limit ourselves to Father/Son duos? Representin' the Father/Daughter duo:
Muhammad & Laila Ali
What other father/son duo each hit a homerun in the same game? Nuff said.
Love the fact that the Winslows have a zero.
Archie and Adam Griffin.
Dustin Fox was our leading tackler as a corner.... because his guy always caught the ball.
Adam is his nephew
/Duff'd It
Incorrect. Adam is indeed Archie's son. One of three.
Jack & Gary Nicklaus.
Hard to beat the Griffey's and the Manning's, though.
Woody and Archie. When I was a kid they always seemed like father and son to me. Maybe Lee and his Tressell boys.
Griffeys actually played on the same team at a point in time-- that's awesome.
Where is Barry and Bobby Bonds? I'd pick them over the Winslows anyday.
Being a Tigers' fan I would also like to add Cecil and Prince Fielder to the list as well. Still not above the Griffeys or Bonds but worth noting.


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Maybe 2/3 in terms of NUMBER of songs but not in terms of volume of music. Six Degrees, A Change of Seasons and Octavarium, only three songs, combine for over 90 minutes of music which could be up to 15 of their under-10 minute songs. My guess is that in terms of the overall volume of their catalog more than half would be missing if songs over 10 minutes were excluded.
If ever there was a compelling reason for HMX to address this issue, having perhaps THE pre-eminent progressive band of the last 15 years willing to put their entire catalog on the RBN would be it. Seems to me HMX would HAVE to adapt to provide DT this opportunity.
EDIT: didn't realize this thread went back six months ago. Sorry for necro-posting.


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NCAA tournament: East Region breakdown
School: Terry Sanford
Sport: Track
Year: Senior
Notable: Rose ran the 300-meter hurdles in a time of 43.44 and ran a personal best 16.54 in the 110 hurdles, winning both events at the Bulldogs' March 14 meet.
School: Fayetteville Academy
Sport: Baseball
Year: Freshman
Notable: Campbell went 6-for-10 over three games. He hit three doubles, a triple and two singles, scoring six runs and earning five RBIs.
School: Jack Britt
Sport: Soccer
Notable: Brookes scored the game-tying goal against Wilson Fike at the Brittany Willis Memorial Scholarship tournament March 15.
Year: Junior
Notable: Davis was 7-for-10 with a double, five RBIs and four runs scored last week. He earned a win on the mound against Scotland, pitching four hitless innings and striking out two.
School: Douglas Byrd
Sport: Softball
Year: Sophomore
Notable: Quinn went 5-for-9 over three games last week. She hit two triples, a double and a pair of singles, totaling five RBIs and six runs scored. On defense, she had two putouts and three assists.
Notable: King scored seven goals and earned three assists in two games last week.
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Red Nonslip Translucent Cutting Board
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Unlike print publications like the local newspaper where you only have one day to reach job candidates, your Jobing.com job listing is online 24 hours a day 7 days a week allowing you to maximize exposure to potential job candidates. Plus, the local newspaper reaches a general local audience who may or may not be interested in your job opening and is only interested in last week's sports scores. At Jobing you receive targeted traffic - local people in Miami Dade who are actively seeking open job positions. Also, if you need to make a simple change to your job ad you can do it real time online on Jobing.com at no additional cost, instead of paying for a new classified ad like at the local newspaper.
But I like having physical resumes to read and review, I can't get that online!
Resumes received through Jobing.com can be delivered in a variety of ways, whether you prefer to receive emails plain text or HTML, have online responses faxed to you or prefer reviewing candidates resumes online, Jobing.com adjusts to your style. We will even route your resumes to multiple email addresses or people if you choose. If your files of resumes are crowding you out of your office, we can help with that too. At no additional cost, Jobing.com offers you full use of our applicant tracking system, the Jobing Recruiting Desktop to review, store and file all of your resumes in one place, and, since it is online you can access these resumes for anywhere you have an internet connection.
Related Articles: Why Switch to Jobing?


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Had an excess lumpiang bangus filling and I was too lazy to wrap it up to make spring rolls (lumpia) so I just made them into fish cakes.
I mixed all purpose flour and cornstarch in a bowl, some freshly cracked pepper and salt, mix well. Then add an egg and beat nicely. Mix everything well. Fry.
This is so yummy. Ok I'm going to share a secret. Whenever I feel like I need to lose a few lbs. and is already thinking is apidexin safe, I eat milk fish. This works like a charm for me. When I'm tired of spring rolls, I make this.


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Meet Our Training Corps
Facilitating Suicide Bereavement Support Groups for Adults
Franklin Cook, M.A.
Franklin Cook is owner of Unified Community Solutions, a private consultancy in Boston, Mass., specializing in suicide grief support and education as well as in project development, management, and leadership. He served from 2010 to 2012 as Director of Survivor and Bereavement Programs for SAVE (Suicide Awareness Voices of Education). Franklin began his career in suicide grief support in 1999 as a volunteer with Black Hills Area Survivors of Suicide and co-facilitated the group for 10 years. He also served as a member of the Pennington County (S.D.) LOSS Team. He helped found the Front Porch Coalition in 2001, a grassroots suicide prevention task force in Rapid City, S.D., and served for four years as FPC's first executive director.
During his time in South Dakota, Franklin co-authored the S.D. Strategy for Suicide Prevention and continued facilitating its implementation through 2010, including working on project management and training for two Garrett Lee Smith projects there. For many years, he was a member of the Survivor Council of the American Foundation for Suicide Prevention (AFSP) and continues as a trainer with AFSP's Suicide Bereavement Support Group Facilitator Training. Franklin was a member of the board of directors of the Suicide Prevention Action Network (SPAN USA) for six years, prior to its merger with AFSP in 2009. He is also a longtime member of the Survivor Division of the American Association of Suicidology (AAS). He edited and published the online news magazineSuicide Prevention News and Comment from 2008 to 2010 and now blogs at www.personalgriefcoach.info. Franklin is a survivor of his father's suicide in 1978.
John R. Jordan, Ph.D., F.T.
John (Jack) Jordan is a licensed psychologist who maintains an active private practice in Wellesley, MA, and Pawtucket, RI. He has specialized in work with survivors of suicide and other losses for more than 30 years and is a Fellow in Thanatology from the Association for Death Education and Counseling (ADEC). He has run support groups for bereaved parents, young widows & widowers, and suicide survivors, with the latter running for over 13 years. He was also the Founder and the Director until 2007 of the Family Loss Project, a research and clinical practice providing services for bereaved families. Jack is the Clinical Consultant for Grief Support Services of the Samaritans in Boston, Professional Advisor to the Survivor Council of the American Foundation for Suicide Prevention (AFSP), and a former Board member of AFSP's former New England Chapter and ADEC. In 2006 Jack was invited to become a member of the International Workgroup on Death, Dying, and Bereavement, and was the recipient of the ADEC 2006 Research Recognition Award. He has been involved in several research projects on the needs of people grieving after a suicide, and in 2004 received research funding from AFSP.
Jack has provided training nationally and internationally for therapists, healthcare professionals, and clergy throughPESIHealthcare/CMI Education, AFSP, and as an independent speaker. He has also helped to organize and lead many healing workshops for suicide survivors. Jack has published clinical and research articles in the areas of bereavement after suicide, support group models, the integration of research and practice in thanatology, and loss in family and larger social systems. He has published in professional journals such asOmega, Death Studies, Suicide and Life-Threatening Behavior, Psychiatric Annals, Crisis, Grief Matters,andFamily Process. He is the co-author, with Bob Baugher, ofAfter Suicide Loss: Coping with Your Grief, a book on suicide bereavement for surviving friends and family. He is the co-editor, with John McIntosh, of the new bookGrief After Suicide: Coping with the Consequences and Caring for the Survivors(Routledge), a professional book on the impact of suicide and interventions to help suicide survivors.
Doreen Marshall, Ph.D.
Doreen Schultz Marshall is an Assistant Professor in the Counseling Department of Argosy University in Atlanta, Georgia. Dr. Marshall previously served as the Associate Director of the Link's National Resource Center for Suicide Prevention and Aftercare. A member of AFSP's Survivor Council, she has conducted research and clinical work in survivor issues, has worked as a consultant in suicide prevention and aftercare since 2000, and is herself the survivor of her fiancé's suicide. She holds a Ph.D. in Counseling Psychology from Georgia State University and an MA in Counseling from The College of New Jersey.
Andy McNiel, M.A., L.P.C.
Andy McNiel serves as Executive Director of the National Alliance for Grieving Children, a national network organization that facilitates communication between hundreds of children's bereavement centers nationwide and conducts professional workshops across the country. Andy has provided organizational leadership for over twenty years, most recently serving as Executive Director of The Amelia Center, a grief counseling center in Birmingham Alabama. He has also served as Director of Grief Counseling Services for Hospice of Martin & St. Lucie in Stuart, Florida.
A highly-experienced bereavement support group facilitator, Andy has facilitated numerous groups for bereaved parents, widows and widowers, children, and teenagers. A Licensed Counselor, he has also provided individual bereavement counseling to children, teenagers, and adults. Andy has also lectured extensively on support group facilitation, grief and bereavement, and building resiliency. Andy holds a Bachelor of Arts in Religion from Palm Beach Atlantic College and Master of Arts in Counseling from The University of Alabama at Birmingham. He is a Licensed Counselor with the State of Alabama.
Wendy M. Resnick, R.N., M.S., C.S.
Wendy Resnick is a Clinical Nurse Specialist in Psychiatric Nursing. For ten years, she worked as a psychiatric nurse in inpatient psychiatry and chemical dependency centers. In 1986, she co-founded The Depression and Related Affective Disorders Association (DRADA), a non-profit organization focused on education and support for persons affected by mood disorders and their families. She was Editor of DRADA's newsletter, published quarterly and distributed nationwide. She developed a network of mutual-help support groups across the mid-Atlantic area and a one-to-one peer support program serving individuals nationwide.
Wendy created a nationally renowned group leader training program, and for the last twenty years has taught thousands of individuals to facilitate effective support groups. She is the author ofThe Manual for Mood Disorder Support Groups. She provides group leader training and consultation to leaders of all types of groups, and provides ongoing training to The Compassionate Friends, an international organization to help bereaved family members. She works with the American Foundation for Suicide Prevention as a trainer and consultant to support group leaders for survivors of suicide support groups. Wendy was recently appointed as an adjunct faculty member at The Catholic University of America.
Edmond Yomtoob, Psy.D.
Edmond Yomtoob earned his Doctorate in Clinical Psychology at the Chicago School of Professional Psychology in 2000 and is also the survivor of the suicide of his mother, Farideh Yomtoob, over a decade ago. Dr. Yomtoob facilitates bimonthly survivor support group meetings for the GLBTQ community in Chicago, and is working to develop culturally-sensitive support groups for other underrepresented communities. He is a member of the American Foundation for Suicide Prevention's national Survivor Council and also serves as President of AFSP's Greater Chicago/ILLINOIS Chapter, as well as chairing that Chapter's survivor initiatives committee. Dr. Yomtoob's private practice specializes in grief, loss, men's issues, GLBTQ issues, anxiety, and depression.


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XNA didn't just pop up overnight. It was something MS had been planning for some time. Mainly it's a platform for people to develop their own games and possibly earn money. HMX simply took that idea and decided it was also and excellent way to expand their game by allowing bands that normally wouldn't have the opportunity to create and sell their own songs.
Maybe it's possible for SONY (and Nintendo) to create their own XNA-style service. But until that happens, RBN is the domain of the Xbox and only a certain selection of songs (determined by things like sales or band popularity or even if HMX just wants to do it) will be converted and submitted for PS3 and Wii.


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SVBC is looking for at-large members to join our Membership Advisory Committee (the "Membership Committee"). The Membership Committee is an advisory committee only, but its recommendations are heavily relied upon by the Board of Directors and the Executive Director to make decisions regarding their efforts to increase the number of members and members' level of engagement in SVBC's work. You can read the committee charter here.
Members of the committee must be available to meet on the second Tuesday evening of the month, starting March 13, in Mountain View. The first meeting will take place at Red Rock Coffee, located 201 Castro Street. We'll have time to socialize from 6:00 to 6:30, and the meeting will run until 8:00 pm. Food choices at Red Rock are limited, so plan accordingly!
If you are interested in attending the first meeting to learn more, please RSVP to email@example.com. If you would like to apply to join the committee, please send a letter of intent introducing yourself and explaining why you would like to join.
Hi Jen,
Hi Jen,
I linked with your apply button and got a Financial Aid School Assistance instead of a Committee Join page. So please reply with a new link for joining/interest. Thanks,
Brian Chun


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Treffen / Madison Square Park (Out front of Shake Shack)
kingofbrickcityVor 8 Monaten - Geantwortet
I'll Be There!
lexisplayhouseVor 8 Monaten - Geantwortet
Hope it's awesome
gurrrl-interruptedVor 7 Monaten - Organisator
gurrrl-interruptedVor 7 Monaten - Organisator
If some of yal don't know anything about me, I set up the meet up as I am in NYC for this whole month and know zero people in the city. I wanted to meet some cool azz people to hang out with do movies/food/shopping/ whatever when I'm here! I arrived a few hours ago today after leaving Scotland last night at 11pm!!! The subway and so on was holy overwhelming and theres a 93% chance I'm gonna get lost before the meet up tomorrow but I will be there at 2.30 no doubt! Ps kinda starting to freak out about it, I NEVER organise things!!! see yal tomoz
gurrrl-interruptedVor 7 Monaten - Organisator
oh man! if no one turns up to this i'll be sitting in shake shack drowning my sorrows in milkshake alone!
himlen-av-vansinneVor 7 Monaten - Geantwortet
I'm hard to miss, I have red and blond hair haha
benten-zingVor 7 Monaten
Update on where you go because I'm going to be late
gurrrl-interruptedVor 7 Monaten - Organisator
We are in the que for shake shack, holy shit it's long!! And as said above ^ the blonde and red hair is hard to miss!


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Switzerland is famous for its delicacies: Chocolate, cheese, fondue (OK, that's just more cheese). The Swiss also love something they call "nusstorte," or nut cake. This caramel-soaked walnut-filled treasure originated in the Engadine valley (though walnuts don't grow there–strange), which is where the Hotel Paradies happens to be located.
Making nusstorte is relatively simple. You probably have the ingredients in your pantry right now. All you need is the recipe …
… And here's the recipe, courtesy of Epicuious. So get baking! (Yes, it's in metric, but the it is a Swiss dessert after all.)
For the pastry:
- 350 g flour
- 200 g butter
- 200 g sugar
- 1/4 teaspoon salt
- 1 egg, beaten
For the filling
- 200 g sugar
- 2 tablespoons water
- 250 g walnuts, coarsely chopped
- 150 ml heavy cream
- 3 tablespoons honey
- 1 egg white
- 1 egg yolk
- 2 tablespoons heavy cream
Put all the ingredients for the pastry in a food processor and pulse until homogeneous.
With the dough prepare 2 balls (2/3 and 1/3 respectively of the dough) and keep in the refrigerator for at least 30 minutes.
Put the sugar, water and honey in a large heavy-based saucepan over medium heat. Stir gently to dissolve the sugar. Bring to the boil and let it continue to boil until it becomes a dark golden color. Stir from time to time.
Add the nuts and the cream until and stir the walnuts until well coated. Remove the saucepan from the heat and. Set aside to cool.
Preheat the oven to 180°C (355 F) Grease a 30 cm tin. (or a 28″ springform pan)
Roll out the larger ball between two sheets of cling film to a 34 cm circle and use it to line the tin of 30 cm square. Press the edges of the pastry against the side of the tin.
Scrape the filling onto the pastry. Level the top as well as you can, but don't apply too much pressure, or you may tear the pastry and the filling will leak out. Fold the excess pastry inwards over the filling.
Roll the second piece of pastry to a neat 29 cm circle. Moisten the edges of the pastry base in the tin with the egg white and position the second pastry circle on top of this. Use a fork to crimp and seal the edges Mix the reserved egg yolk with 2 tablespoon cream and brush the cover. Prick with a fork in several places. If you like, you can score a plaid pattern onto the surface with the fork.
Bake for 35-40 minutes, or until golden brown. Leave to cool until lukewarm in the tin, then loosen the sides, release the clip and carefully transfer the pie to a wire rack to cool completely.


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1962 Jaguar Mk ll 3.4 to Beacham Specification Chassis No. 178447 DN: Left Hand Drive Ex Swiss Supplied & Title: Dr.Greg Beacham turned his hobby of restoring... More
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JAGUAR: 1962 Mark II 4-dr sedan, unrestored, good condition, $6,500. 972-247-2007, TX; [email]... More


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In this Discussion
- Browniepetersen November 2012
- commodorecollector December 2012
- Huddy42 November 2012
- Lee ODell December 2012
- lostmind November 2012
- oldhudsons November 2012
- Tallent R November 2012
Top Leaders
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South California Trip Dec 1st.
As of December first I am heading down to SoCal to prep and load the 1947 C6 Hudson. The independent shipper I have hired promised to have the car in Sacramento on Sunday which will be nice, and I am going to get all the paperwork done the same week, so *fingers crossed* I should have her back on the road as soon as december 10th.
As for the fate of this 1947 Hudson, I am going to do all the body work and repaint her during my first specialization (street rod) and repair her interior in my Upholstery specialization. Which means, she will be completely restored by September 2013. Minus the engine of course. Once I get her numbers, I would like to track down her original L6 if it still exists.Christopher
Wyotech Sacramento Grad 2013
- Collision and Refinishing
-Applied Service Management
NW Chapter
Collecting, Restoring and Selling Hudson's -
This to me appears to be a 1946, 1947 has the extra section on the nose cone, and the '47 has twin door locks, not being picky, but, just telling the difference that I know of, I could be wrong and it would not be the first time.LOL
The photos shown are what we have found in Australia.
The one parked betwen the lines side view is 1946
The one backed in to the kerb is 1947, notice the extra little raised bit of chrome on the nose cone.
This is the difference I have found, we never did get any 1947 Hudson's here in Australia all we got were 1946 with out that extra chrome piece.
Please let me know if that is correct or not. Never too old to learn.P7120026.JPG640 x 480 - 2MP7120018.JPG640 x 480 - 768K -
Your obervation in most cases would be correct identification. However, not with this car.
46 Commador 6 serial number starts with 32.
47 Commador 6 serial number starts with 172.
The car Chris is buying has the serial number that starts with 172.
I had the same thoughts you had until I double checked the serial number. When I was asked to help with the estate sale of all the cars, I had been told this car was a 47 Commador 8. Not so.
Also, many 46, 47 Hudsons listed in the HET Club Roster have the wrong year when compared to the serial number listed for the car. Those owner mistakes may possibly have been sent in too be printed in the roster because of similar reasons mentioned.
Lee O'Dell -
Thanks for the input guys, as we are always open to others points of view and reasons why, having been around Hudson cars for over 50 odd years, nothing surprises me any more from the Hudson Motor company, they quite often used parts from the previous model or vice versa, and especially the cars that we ended up with here in Australia.
All the 1946 Hudson sedans that we have here have the old 1939 bodies with the two piece rear windows , sloping trunk, and high rood line, unlike the 1942 Brougham we own with the one piece rear window, the larger rear trunk and flatter roof line, Aussie 1946 Hudson pictured.1947HudsonAussieBody.jpg320 x 171 - 15K -
WoW , interesting . didnt realise that . thanks for the photo,
RogerRetired Tech. -
Chris, Great looking car. I saw it last week while I was picking up my car. A very complete car and should be a fun project to put back on the road. I expect to have mine up and running but doubt it will be finished as soon as yours.Brownie
I am looking forward to heading down tomorrow to SoCal to get the Hudson ready and shipped back to Sacramento. The only thing that might make it interesting to say the least in the weather, since it looks like it is going to be wet and windy for the next few days. Free car wash I guess.. lol
Wyotech Sacramento Grad 2013
- Collision and Refinishing
-Applied Service Management
NW Chapter
Collecting, Restoring and Selling Hudson's -
If my memory is correct , the trunk emblem on 46 cars was plastic , and in 47 it was cast metal.
What happened after it left the factory ,who knows? -
Lost - right, and I believe the '46 radio has a gold facing whereas the '47 is silver.
Yesterday, besides the weather everything came together. Lee helped me pick up the new tires of the car and I put them on and the shipper came in good time. It is going to arrive in a little while in Sacramento.
Thank you Lee ODell for helping me get around and getting to meet other HET members to see their cars.Christopher
Wyotech Sacramento Grad 2013
- Collision and Refinishing
-Applied Service Management
NW Chapter
Collecting, Restoring and Selling Hudson's -
You are welcome Chris.
Chris would like to find the original 212 engine and trans that came out of his car. If I wrote the serial number correctly here it is just in case someone may have the engine: 17282677
Lee O'Dell -
Yes Lee, you wrote down the serial number correctly: 17282677. I also found a headlight in the trunk beside the spare tire and there were two carbs, one in the car and one in the trunk.
Wyotech Sacramento Grad 2013
- Collision and Refinishing
-Applied Service Management
NW Chapter
Collecting, Restoring and Selling Hudson's