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Managing Electrical Complexity with a Platform Level Approach and Systems Engineering
White Paper
In this competitive and challenging environment, thought-leaders are recommending a shift to systems engineering. Using a systems engineering approach could help OEMs maintain product quality, reduce costs, manage change, and achieve time to market. The Mentor Graphics Capital(r) tool suite for electrical design and manufacturing fits well into the systems engineering methodology. This paper talks about applying systems engineering principles using the Capital tool suite to address these issues.
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The move from one abstraction level to another transitions concept to implementation. Some of today's transitions are essentially manual tasks but others can be automated. Examples include network...
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Systems Engineering At The Platform Level
Technology Overview 41:12Systems Engineering At The Platform Level
This presentation explores how Mentor's Capital software models platform connectivity across abstractions. It shows how new technology allows companies to understand the impact of and respond to changes...
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Yazaki Europe IT Strategy and the Experience with...
Technology Overview 23:34Yazaki Europe IT Strategy and the Experience with Mentor Tools
Yazaki Europe has a long experience in standardising ERP applications. Angelo Mattivi will explain what parallels can be drawn between ERP and engineering world, what benefits can be achieved through a...
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subset: commoncrawl


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A policy change for an Oregon-based company is expected to result in the loss of about 60 local jobs.
The Greenbrier Companies Inc., a provider of equipment and services to the railway industry, announced Thursday that the company has reached an agreement to sell all of the equipment used at its reconditioned wheelset rollerbearing operations facility on Peterson Drive in Elizabethtown.
Greenbrier and buyer The Timken Company also entered into a long-term supply agreement for Timken to provide Greenbrier with reconditioned and new bearings. The companies didn't disclose the amount for which the equipment was sold.
The Elizabethtown location is the only bearings facility held by Greenbrier.
The operation in Elizabethtown is profitable, but recent changes in rules related to reconditioned components and lacking availability of certain key materials caused Greenbrier officials to choose to get out of the bearing business, according to a news release from the company.
The sale means the closing of operations at the facility after a transition period of about 60 days, Greenbrier spokesman Jack Isselmann said.
The facility employed about 100 people at one time, but that number has shrunk to about 60 since Greenbrier bought it in 2008 through not hiring people to fill vacated positions, he said.
Employees were told about the change last week, and will continue working through the transition period, Isselmann said.
They have been told that anyone qualified for an open position in another Greenbrier facility is welcome to request a transfer. It is likely Timken will make the same offer, he said.
The land and building are planned to be listed for sale after the transition period, Isselmann said.
Amber Coulter can be reached at (270) 505-1746 or email@example.com.
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hello im going into 9th grade and have used jolly before, he did the first phase of my teeth but we cant afford to do the second pase which is a full set of braces. when i take pictures i never smile and i always get picked on for my teeth. it has always been my dream to have streight teeth for senior pictures and if i start my braces right now then there is a possibility that my dream will come true. please help me
want pretty teeth before senior pictures
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- November 18, 2012
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LottoWinner writes:
in response to richardwicks:
It's good to see that Hillary Clinton received less votes than Mickey Mouse. That woman is the worst possible woman that this nation could possibly have as president.
She voted for the Authorization to Use Force in Iraq, she voted for the Patriot Act, she's mute on drone attacks and was under Bush, and generally she's a completely unethical hypocrite. She's every bit a neocon as George W. Bush was. She supported all of his horrific policies, and she still does now that Obama has adopted them.
It appears that she's connected to drug money as well in the attempts to depose Correa in Ecuador. Hopefully, that pile of garbage will be put on the same landfill that Oliver North was.
It's depressing we allow people so bankrupt of any moral character to have any power whatsoever in this country. I suppose it's a reflection of the populace at large.
Idiot must be your middle name. Obviously you didn't read the article or are you just pulling an old Flip Flopney? She did get more votes than the mouse and the rest of that crap you say is typical from a Romney kiss _sser.
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You are here: Home > Environment > Conservation and listed buildings > Conservation areas in the district > Drayton Parslow Conservation Area
Cobblestones, Church End, Drayton Parslow
The new Drayton Parslow conservation area was adopted by full council on 3 March 2004
This followed a six week consultation with the public and consideration of their comments by the councillors.
Follow the links below to download the document and other useful information about conservation areas. The document is also available to buy for £5.00 (+0.95 P&P).
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Date Updated: 07/01/13
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You're watching...
Tax Savings Driving People to Florida?
HedgeCo CEO Evan Rapoport on the tax advantages that are motivating many to move to the state.
Jan 30, 2013
You're watching...
HedgeCo CEO Evan Rapoport on the tax advantages that are motivating many to move to the state.
Jan 30, 2013
Also in this playlist...
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It escaped from New York.
You know it's not just something retirees say a growing number of working professionals are leaving new York and other states in the northeast for better conditions down south.
And -- -- not just leaving for a lower taxes and more sunshine so what's the big drive joining me now -- Rappaport.
CEO of PepsiCo who is from New Jersey and now calls West Palm Beach is -- -- I can't tell you have been to West Palm Beach many times that's a nice place to live my friend.
Congratulate -- CEO.
Thank you so much Gerri thanks for having me also you you're welcome good good to have you here tongue -- to how you came to make this decision what was at that pushed out of New York.
-- glad he did it.
Oh absolutely well I I am some of -- went down to the University of Florida for college and was dying to get back frankly so I went.
And worked on Wall Street for seven years and when I started my own company.
I have the ability to go ahead and an open up down here and West Palm Beach.
I think some of the deciding factors wore the affordability.
Certainly of starting a business down here in the operational expense which was in a much lower than it would be -- New York City.
All right let's show folks what state and local taxes look like New York compared to Florida New York 14%.
Florida at 0%.
What does this mean to you in dollars and cents for your company.
Well I mean means a lot and and we talk about the hedge fund industry in general.
-- and I I think these numbers are critically impact -- -- -- let's take an example write a fund manager who makes a million dollars a year which is not unusual in our industry.
He's getting taxed if he lives in New York City at fourteen point 7%.
That's a 147000.
Dollars that's very impact fall and and and.
Not -- average -- painful my friend I'm talking I'm -- crying yourself to sleep every night.
I've absolutely that's a lot of Dell a lot of money and then you've got a pile on federal income taxes on top of that and goodness knows what else.
You know -- -- just running some numbers because you know professional sports figures get a lot of attention on this score.
We've figured out the tiger would say -- hundred million dollars over the course of his golf career sixteen your career if he had moved to a note income tax state.
And Phil Mickelson has been talking that was very publicly recently with say 53 million dollars.
Do you think that your the canary in the coal mine here that lots of people are gonna follow you.
Well yes and tiger is a resident of Florida so tigers a resident of Jupiter which is not too far from last night I -- around.
But but not not that but you know Phil Mickelson made that that that point all somebody's giving away a large sum of his income.
My living in California and if he was to move to Florida he would save the quite a lot of money and I think there was probably some of the reasons behind.
You know even some of the sports figures as you've mentioned moving down here.
Like some of the members of the Miami Heat.
Well you -- you've you've mentioned taxes but there are other reasons to what are the other attractions.
That's a living in Florida.
While sort of taxes you certainly have a great lifestyle.
For those that enjoy -- activities voting.
Playing golf year round -- tennis I think Florida second to none.
Also the -- -- the haven't they can they can get.
That commute time I don't have I have probably fifteen minutes of a commute I have no tolls to pay.
My parking on a monthly basis you're ready 25 dollars a month -- -- Jackson in order and property taxes like.
Property taxes are low it depends on the municipality but you know -- certainly less than let's say 2%.
And so the sales tax is lower how about know what state tax Jerry.
And so when you're talking while planning your State's.
-- give -- to give away six to 10%.
Of your money to the state.
It's it's a big number.
Our I have to go for one more graphic here because I found it fascinating.
We went to united they analyzed to ask okay where -- people leaving from.
New York New Jersey Connecticut Michigan Illinois with the big inbounds states DC Washington DC because they have all the money.
Oregon Nevada North Carolina -- that's where I'm from South Carolina so people who don't -- -- That's definitely the case they tell us a quick story before we came to air saying that.
You were able to actually nab.
A present for your company that you otherwise would not have been able to get if you if he would -- And moved to new Yorker New Jersey.
That's -- and he's a perfect example.
-- -- -- president Brett Lambert he was a managing director UBS and down and every day he would wake up at 430.
And he would get today to the office after going through tremendous commute from New Jersey spending a ton of money.
On on gas on tolls on.
And parking.
Finally get into the office in getting home late in the evening and what they did was.
It did this allowed him to enjoy his his child's.
Or that -- his child's life.
Where he he'd be basically missed out right because he didn't see them grow up he he.
He miss them because of the -- and because of the workload whereas here he's able to come to work at 830.
Go home at 530 and enjoy that time with his children that he otherwise would not have.
-- able to have wow I can so relate to that.
Until push all the prices in Florida through the roof on real estate other people may wanna buy I may join you haven't they still pretty broad Jerry -- up up -- -- Thanks so much.
My pleasure thanks for -- --
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Tuesday | Verde Independent
Verde Valley felons still walking streets
As part of Yavapai County's seasonal Catch-22 initiative to lock up outstanding felons, the effort is looking for three that were last known to live in the Verde Valley.
Should the minimum wage be raised to $9 per hour?
Could you survive the end of civilization?
Tuesday | Verde Independent
Nic's returns with best chocolate for second year
Despite chilly blustery weather Saturday evening, the Old Town Association chalked-up another sellout of the ever-popular Chocolate Walk.
Tuesday | The Bugle
Catch 22: Seeking three wanted men in Verde Valley
As part of Yavapai County's seasonal Catch 22 initiative to lock up outstanding felons, the effort is looking for three that were last known to live in the Verde Valley.
Tuesday | Verde Independent
Letter: Thank you Food City for Thanksgiving joy
Thank you Food City and everyone who made turkey and food donations. Your generosity helped many families enjoy a Thanksgiving dinner they may otherwise have gone without.
Start the New Year with First Day Hikes at State Parks on January 1
Each year America's State Parks announces a national collaboration of all 50 State Park systems across America to sponsor guided "First Day Hikes" on New Year's Day.
Cities, towns weather October downturn in sales tax revenue
Out of four Verde Valley communities, Cottonwood was alone in increasing its collected sales tax revenue in October, at about 5.7 percent more than the same month last year.
Hot debate over civil unions in Cottonwood
The passion in the room was so thick it could be cut with a knife. There were no smiles; everyone in the audience was deadly serious.
Hell's Angel in Cottonwood bar fight
The Yavapai County Gang and Immigration Intelligence Team Enforcement Mission detectives assisted Cottonwood Police Department with an investigation at Rockin B Saloon in Cottonwood for a report of a fight Aug. 10. Two males allegedly assaulted another male following an arm-wrestling match.
Celebration of Christmas takes stage at Emmanuel Fellowship
EF Productions brings Christmas magic to Cottonwood with their 19th annual "Celebration of Christmas," which opens tonight, December 6, and runs until December 9. The musical production held at Emmanuel Fellowship Church features talented actors and a wealth of extras from the local community, a live orchestra, impressive stage effects and a ... (more)
Deputies detain/cite 25 for trespass inside vacant Verde Village home
Nov. 30, around 12:30 a.m., Yavapai County sheriff's deputies were called to the 1600 block of South Carpenter Lane in Verde Village, regarding suspicious people and vehicles in the area.
Volunteers needed to install medical alert units for at-risk older adults
Verde Valley Caregivers is in need of volunteers to help install Guardian Angel Medical Alert Units to older adults who live alone and are at risk for falling down.
Editorial: Christmas season has obviously arrived in Verde Valley
From Cottonwood to Camp Verde to Clarkdale and up the mountain to Jerome, no one throws out the welcome mat for the holiday season as does the Verde Valley.
Black Friday: Cottonwood mom and pops offer big box deals
Cottonwood's Old Town district provided ample proof Friday that traditional mom-and-pop stores can compete with big box retailers on Black Friday.
Construction begins for slag harvesting project in Cottonwood
Minerals Research and Recovery has been harvesting a former copper mine slag near an Ajo, Ariz., for abrasives for things like sand paper and asphalt roofing tile.
Cottonwood Fire Department smoke detector program benefits El Rio del Oro Mobile Home Park
Fire personnel installed smoke detectors in 35 homes and distributed an additional five detectors to residents in the community who wanted to install the detectors themselves.
Mother, daughter donate 16 inches of hair for cancer patients
Eight-year-old Leah Pedersen sat in her booster seat Tuesday afternoon as a stylist at Teaser's salon in Cottonwood put eight inches of her long blonde hair into a ponytail and snipped it through.
Verde Valley Voices present 'Be Joyful!' Christmas Concert
The Verde Valley Voices will hold their Christmas Concert "Be Joytful!" Saturday Dec. 7 at the Mingus Union High School Auditorium,.
Letter: Citizen Police Academy was a great experience
Thank you, Chief Fanning and Sergeant Savage. My wife and I had the opportunity to attend and complete the Cottonwood Citizen Police Academy, class of 2013.
Letter: Help protect homeless neighbors during winter months
The Loft opened in 2010 in answer to the lack of shelter for our homeless neighbors.
With the Flying High Turkey Drive complete, the Old Town Mission began distribution of complete Thanksgiving Day meals on Tuesday morning, continuing on a first come-first serve basis until exhausting the 600+ meal boxes.


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A new study suggests that, by the end of the century, "Katrina-like extreme events" could become as much as 10 times as commonplace due to changes caused by global warming.
Using more than 10 different climate change predictor models, Aslak Grinsted, a climate scientist with Denmark's Centre for Ice and Climate, says that the world has seen a "significant positive trend" of strong hurricanes, and that the trend is likely to continue as global temperatures increase.
"It's not great that there are going to be more disasters," he says. "But it's comforting to me as a scientist that all the models agree about this."
[ENJOY: Political Cartoons on Global Warming]
Though climate scientists have long contended that climate change has led to more extreme and common hurricanes, they have been reticent to blame any single hurricane on climate change. Grinsted says that's still the case—there have been hurricanes the size of Katrina roughly once every 20 years since 1923—but it's reached the point where any given hurricane is more likely caused by climate change than not.
"Whenever we're asked whether Katrina or Sandy was caused by global warming, we have to give the standard answer that no single event can be attributed to warming," he says. "Well now, the odds have changed sufficiently and it's misleading to people to trot out the standard answer."
According to his research, "we have probably crossed the threshold where Katrina magnitude hurricane surges are more likely caused by global warming than not."
[PHOTOS: New York's Damage From Superstorm Sandy]
Grinsted wrote a study published in September that used historical data to prove that hurricanes were more severe and more common in years that the Atlantic Ocean was warmest. He says his latest study is a "companion piece" to that study. His predictions are based on projected ocean warming temperatures, not predicted sea level rise, which the U.N. Intergovernmental Panel on Climate Change says could be as much as two feet worldwide by the year 2100.
"We're taking out the effect of the tides and the effects of sea level rise," he says. "Given those, this is effect is likely to be even more extreme."
Though there are likely to be more hurricanes, Grinsted says that not every hurricane that is as strong as Katrina will have the same devastating effects.
"Katrina was such a disaster because New Orleans wasn't prepared," he says. "This shows we have to adapt our coastal infrastructures to be able to deal with extremes."
More News:


text:
Systematic (IUPAC) name | |
'2-methyl-3-o-tolyl-4(3H)-quinazolinone; 3,4-dihydro-2-methyl-4-oxo-3-o-tolylquinazoline; 2-methyl-3-(2-methylphenyl)-4-(3H)-quinazolinone |
Clinical data | |
Pregnancy cat. | D (US) |
Legal status | Prohibited (S9) (AU) Schedule III (CA) Schedule I (US) |
Identifiers | |
CAS number | 72-44-6 |
ATC code | N05CM01 |
PubChem | CID 6292 |
DrugBank | DB04833 |
ChemSpider | 6055 |
ChEMBL | CHEMBL282052 |
Chemical data | |
Formula | C16H14N2O |
Mol. mass | 250.30 g/mol |
Physical data | |
Melt. point | 113 °C (235 °F) |
(what is this?) (verify) |
Methaqualone (meth-a-KWAY-lohn; brand name Quaalude /ˈkweɪluːd/ KWAY-lewd) is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant.
The sedative–hypnotic activity of methaqualone was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan.[1] Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant. It has also been used illegally as a recreational drug. Clandestinely produced methaqualone is seized by government agencies and police forces around the world.
Methaqualone was first synthesized in India in 1951 by Indra Kishore Kacker and Syed Hussain Zaheer, for use as an antimalarial drug.[2] [3][4] It was soon introduced to Japanese and European consumers as a safe barbiturate substitute.[citation needed] By 1965 it was the most commonly prescribed sedative in Britain, where it has been sold legally under the names Malsed, Malsedin, and Renoval. In 1965 a Methaqualone/antihistamine combination was sold as the sedative drug Mandrax, by Roussel Laboratories (now part of Sanofi-Aventis). In 1972 it was the sixth-bestselling sedative in the USA,[5] where it was legal under the brand name Quaalude.
Quaalude in the United States was originally manufactured in 1965 by the Fort Washington, Pennsylvania based pharmaceutical firm William H. Rorer Inc. The drug name "Quaalude" shared a stylistic reference to another drug marketed by the firm, Maalox, and was a shortened version of the phrase "quiet interlude".[6]
In 1978, Rorer sold the rights to manufacture Quaalude to the Lemmon Company of Sellersville, Pennsylvania. At that time, Rorer chairman John Eckman commented on Quaalude's bad reputation stemming from illegal manufacture and abuse of methaqualone, and illegal sale and abuse of legally prescribed Quaalude:
"Quaalude accounted for less than 2% of our sales but created 98% of our headaches."
Both companies still regarded Quaalude as an excellent sleeping drug. Lemmon, well aware of Quaalude's public image problems, used advertisements in medical journals to urge physicians "not to permit the abuses of illegal users to deprive a legitimate patient of the drug". Lemmon also marketed a small quantity under another name, Mequin, so doctors could prescribe the drug without the negative implications.[2]
The rights to Quaalude were held by the JB Roerig & Company division of Pfizer, before the drug was finally discontinued in the United States in 1985, mainly due to its psychological addictiveness and recreational use.[7]
Methaqualone is a depressant that increases the activity of the GABA receptors in the brain and nervous system. When GABA activity is increased, blood pressure drops and the breathing and pulse rates slow, leading to a state of deep relaxation. These properties explain why methaqualone was originally mainly prescribed for insomnia,[8] most commonly in 300 mg dosage.
Methaqualone peaks in the bloodstream within several hours, its effects generally lasting four to eight hours. Regular users build up a physical tolerance, requiring larger doses for the same effect. Overdose can lead to nervous system shut down, coma and death.[9]
Methaqualone is not recommended for use while pregnant and is in pregnancy category D.[10] Methaqualone is available in Canada by prescription as a Schedule III drug[citation needed]. It is banned in India.[11]
Methaqualone became increasingly popular as a recreational drug in the late 1960s and early 1970s, known variously as 'ludes or sopers (also soapers) in the U.S. and mandrakes and mandies in Great Britain. The drug was sometimes used during sexual activity due to heightened sensitivity and lowered inhibition coupled with relaxation and euphoria.[citation needed]
The drug was often used by people who went dancing at glam rock clubs in the early 1970s and at discos in the late 1970s. (One slang term for Quaalude was disco biscuits.) In the mid-1970s there were bars in Manhattan called juice bars that only served non-alcoholic drinks that catered to people who liked to dance on methaqualone.[12]
Smoking methaqualone, either by itself or as an adulterant added to various legal and illegal smoking mixtures, gained popularity in the US among a few during the mid-1970s. Because the various binders and inert ingredients that were contained in the pill form were toxic when smoked, this practice was roundly decried by the medical community as a serious health risk. Smoking methaqualone pills can lead to emphysema and other chronic lung disorders, most notably talcosis.
The drug was more tightly regulated in Britain under the Misuse of Drugs Act 1971 and in the U.S. from 1973. It was withdrawn from many developed markets in the early 1980s. In the United States it was withdrawn in 1982 and made a Schedule I drug in 1984.
Gene Haislip, the former head of the Chemical Control Division of the Drug Enforcement Agency (DEA), told the PBS documentary program Frontline: "We beat 'em." By working with governments and manufacturers around the world, the DEA was able to halt production and, Haislip says, "eliminated the problem".[13][14][15]
Methaqualone was manufactured in the United States under the name Quaalude by the pharmaceutical firms Rorer and "Lemmon" with the numbers 714 stamped on the tablet, so people often referred to Quaalude as 714s, "Lemmons", or "Lemmon 7s". Methaqualone was also manufactured in the USA under the trade names Sopor and Parest. After the legal manufacture of the drug ended in the United States in 1982, underground laboratories in Mexico continued illegal manufacture of methaqualone all through the 1980s, continuing the use of the "714" stamp, until their popularity waned in the early 1990s. Bristol Myers manufactured this drug until taken out of the market in 1982 as well.[citation needed]
Methaqualone is one of the most commonly used recreational drugs in South Africa.[16][17] Commonly known as Mandrax, M-pills, buttons, or smarties, it is not taken orally but is crushed and mixed in a pipe with cannabis. The drug's price of R90[citation needed] (about US$8) together with readily available cheap, low-grade cannabis, makes methaqualone one of the preferred drugs of the lower-income, mid and upper sections of South African society.[16]
Effects can include euphoria, drowsiness, reduced heart rate, reduced respiration, increased sexual arousal (aphrodisia), and paresthesias (numbness of the fingers and toes). Larger doses can bring about respiratory depression, slurred speech, headache, and photophobia (a symptom of excessive sensitivity to light).
An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, renal failure, coma, and death through cardiac or respiratory arrest. It resembles barbiturate poisoning, but with increased motor difficulties and a lower incidence of cardiac or respiratory depression. While the standard one tablet adult dosage of Quaalude was 300 mg, a dose of 8000 mg is lethal. However, a dose as little as 2000 mg could also be lethal, especially if taken with an alcoholic beverage.[2]
Drug testing[edit]
Urine drug test of gas-liquid chromatography (GLC) confirmation up to 72 hours after the last intake is a practical way of detecting methaqualone use in individuals.[18]
To avoid a false positive Substance Abuse and Mental Health Services Administration (SAMHSA) determined the initial cut off level of 300 ng/ml for forensic and workplace drug testing of methaqualone. Only after the confirmatory test of 200 ng/ml will a person be considered positive and possibly face penalties or workplace disciplinary action.[19] As reported by Quest Diagnostics in 2011, methaqualone had a 0% positive drug testing rate in the US, making it one of the least used recreational drugs in that year.[20]
See also[edit]
- Methaqualone in popular culture
- Cloroqualone
- Diproqualone
- Etaqualone
- Mebroqualone
- Mecloqualone
- Methylmethaqualone
- Nitromethaqualone
- ^ US Patent 3135659 - Hydroxy and Alkoxy Aryl Quinazolones
- ^ a b c Linder, Lee (28 May 1981). "Quaalude manufacturer: Image hurt by street use". Lawrence Journal-World (in English). Associated Press. p. 6. Retrieved 16 August 2013. "Eckman/Fisher"
- ^ p. 142, A survey of reported synthesis of methaqualone and some positional and structural isomers, Etienne F. van Zyl, Forensic Science International 122, #2-3 (1 November 2001), pp. 142–149, doi:10.1016/S0379-0738(01)00484-4.
- ^ Potential Analgesics. Part I. Synthesis of substituted 4-quinazolones, I. K. Kacker and S. H. Zaheer, J. Ind. Chem. Soc. 28 (1951), pp. 344–346.
- ^ GC/MS Assays for Abused Drugs in Body fluids, p. 39
- ^ "Dividends: Dropping the Last 'Lude". Time Magazine. 28 November 1983. Retrieved 16 August 2013.
- ^ "Quaaludes Again".
- ^ "methaqualone reference". Enotes.
- ^ "recreational drugs tranquilizers". drug library eu.
- ^ Drug Safety. "Methaqualone in Pregnancy and Breastfeeding". Retrieved 15 August 2012.
- ^ "Drugs banned in India". Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. Retrieved 2013-9-17.
- ^ Lawrence Young (31). "METHAQUALONE". Drug Text. International Substance Use Library. Retrieved 27 July 2012.
- ^ "The Meth Epidemic – Haislip discusses parallels to current Methamphetamine epidemic".
- ^ Ferns, Sean, "Lecture: Gene Haislip : The Chemical Connection: A Historical Perspective on Chemical Control", Drug Enforcement Administration Museum Lecture Series, Arlington, Virginia, October 25, 2007
- ^ Piccini, Sara, "DRUG WARRIOR: THE DEA'S GENE HAISLIP '60, B.C.L. '63 BATTLED WORLDWIDE AGAINST THE ILLEGAL DRUG TRADE — AND SCORED A RARE VICTORY", William & Mary Alumni Magazine, The College of William & Mary, Spring 2010
- ^ a b "Mandrax". DrugAware. Reality Media. 2003. Retrieved 2009-08-13.
- ^ McCarthy G, Myers B, Siegfried N. Treatment for methaqualone dependence in adults. Cochrane Database of Systematic Reviews. 2005 Apr 18;(2):CD004146. PMID 15846700
- ^ "methaqualone drug testing". National Institute of Health.
- ^ "methaqualone drug testing". Testcountry.
- ^ "workplace drug test positive rates". quest diagnostics.
External links[edit]


text:
Posted 12:30 AM 1/30/2013 : Santa Barbara Co. Fire investigators looking into cause of fire at apartment complex
Santa Barbara County Fire Department crews are investigating the cause of a fire in Solvang.
Crews tell KSBY News the fire broke out Tuesday night in a garage of an apartment on Roskilde Road.
Six engines were called out to knock down the fire that spread into the apartment's
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text:
Media Contact:
Lindsey CalabreseUniversity Relations
202 Hofstra Hall
Phone: 516-463-4687
Fax: 516-463-5146
Send an E-mail
Date: Sep 25, 2009
Hofstra Launches Zipcar Car Sharing Program
Zipcar Program Offers Students a Convenient, Cost Effective and Environmentally-Friendly Option to Owning a Car
Hempstead, N.Y— Hofstra University and Zipcar, the world's largest car sharing service, today announced the launch of Zipcar's car-sharing program on campus. The decision to offer Zipcar to the Hofstra community was driven in part by strong student involvement and advocacy, and reflects Hofstra's commitment to a high quality campus lifestyle and a lower carbon footprint.
Beginning today, two self-service Zipcars – one Honda Insight Hybrid and one Honda Civic – will be available for use 24 hours a day, seven days a week. The cars will be located in reserved spaces and are available to all students and staff ages 18 and over. Gas, insurance, roadside assistance, 180 free miles and reserved parking are included in low hourly and daily rates.
Students and staff can join Zipcar for personal use for $35 and can drive for as little as $8 per hour or $66 per day weekdays and $9 per hour or $72 per day on weekends. They will also get $35 in free driving credit as part of a launch promotion.
The partnership with Zipcar is another step toward a greener Hofstra. The university is committed to sustainability with support from students and faculty, including an Environmental Priorities Committee (EPC) that works to include environmental perspectives into issues relating to university life at all levels, from operations to academics to student life, retention and recruitment.
"While there's no doubt that Zipcar is a great addition to our sustainability efforts, the fact that our students felt strongly about the program made the decision even easier," said Vice President of Student Affairs Sandra Johnson. "We're glad that we can provide a service that meets the needs of our students, our university and our community."
Zipcar provides a service that appeals to both the freedom-loving nature of college students who want to experience the world around them and the practical concerns of administrators tasked with running a university and reducing overall costs. Zipcar also offers a practical and proven solution to managing demand for parking, reducing congestion and emissions and adding a lifestyle-oriented service to campus.
"Zipcar is a unique service in that it offers a great lifestyle amenity to students while at the same time addressing parking, congestion and carbon emission issues for universities," said Matthew Malloy, vice president of global university operations for Zipcar."
Zipcar was selected as Hofstra University's car-sharing partner based on its industry leading brand, superior technology and operations, membership experience and track record of providing peer universities with a proven, cost effective and environmentally friendly transportation solution.
Zipcar serves more than 130 colleges and universities across the country. Among the dozens of colleges that have partnered with Zipcar to reduce traffic, noise and parking demands are MIT, Columbia, Georgetown, American University, University of Michigan, Harvard University, University of Minnesota, University of Toronto, University of North Carolina, The University of Chicago, and UCLA.
More information about Zipcar at Hofstra University is available online at: www.zipcar.com/hofstra
About Hofstra University
Hofstra University is a dynamic private institution where students can choose from about 150 undergraduate and more than 160 graduate programs in liberal arts and sciences, business; engineering; communication; education, health and human services; and honors studies, as well as a School of Law. With a student-faculty ratio of 14-to-1, our professors teach small classes averaging 22 students that emphasize interaction, critical thinking and analysis. Hofstra offers a faculty whose highest priority is teaching excellence. The University also provides excellent facilities with state-of-the-art technology, extensive library resources and internship programs that match students' interests and abilities with appropriate companies and organizations. The Hofstra community is driven, dynamic and energetic, helping students find and focus their strengths to prepare them for a successful future.
About Zipcar
Zipcar is the world's leading car-sharing service with 325,000 members and 6,500 vehicles in urban areas and college campuses throughout 28 North American states and provinces as well as in London, England. As a leader in urban transportation, Zipcar offers more than 30 makes and models of self-service vehicles by the hour or day to savvy city residents and businesses looking for an alternative to the high costs and hassles of owning a car in the city. More information is available at www.Zipcar.com.


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Synopsis: Author Anne Michaels's poetic novel comes to the screen courtesy of director Jeremy Podeswa in this period drama concerning a Holocaust survivor who remains eternally haunted by the uncertain fate of his beloved sister. Athos (Rade Sherbedgia) is an archeologist conducting a dig in Nazi-occupied Poland. When Athos discovers a seven-year-old boy nam... Continue Reading
Starring: Rosamund Pike, Rade Sherbedgia, Stephen Dillane, Ayelet Zurer


text:
Ohio Supreme Court agrees to hear JobsOhio case
The Daily Briefing
Buckeye Forum Podcast
The Dispatch public affairs team talks politics and tackles state and federal government issues in the Buckeye Forum podcast.
Your Right to Know
Ohio Gov. John Kasich, right, spoke at a JobsOhio board meeting in Cincinnati last year.
Today the Ohio Supreme Court agreed to consider whether ProgressOhio, a liberal policy group,
has standing to challenge the constitutionality of Gov. John Kasich's privatized development
The liberal policy group has questioned the legality of using state liquor profits as a
funding stream for JobsOhio. The high court's decision to determine whether ProgressOhio has
standing represents at least a small victory for the group after the 10th District Court of Appeals
and Franklin County Common Pleas Court dismissed the lawsuit on the standing question, which
revolves around a legal right to even file a lawsuit.
Liquor profits are estimated to provide up to $100 million a year to fund JobsOhio, a private
nonprofit organization created to entice companies and jobs to the state. After the appeals court
decision, Kasich said he expected the transfer of the liquor profits to begin soon.
Although the Supreme Court decided to rule on whether ProgressOhio has standing to file the
legal challenge, justices did not rule on the merits of the group's claims, which have been joined
by the conservative 1851 Center for Constitutional Law.
ProgressOhio Executive Director Brian Rothenberg said in a statement: "We have said all along
the constitutional questions hovering over JobsOhio deserve to be resolved. Today's Ohio Supreme
Court decision to hear our appeal deals a blow to the Kasich administration's legal gamesmanship,
in which they are asserting no one has the right to sue over the constitutionality of JobsOhio.
"Ohioans should be aware that no court has yet to actually hear and decide on the
constitutional issues that even the Kasich's legal briefs have acknowledged are very real issues.
If no one has the right to take such complaints to court, the Ohio Constitution will be weakened as
cases like JobsOhio will remain in an eternal legal limbo."
Connie Wehrkamp, a spokeswoman for Kasich, said the governor's office does not comment on
pending litigation but is confident the Supreme Court will follow the lower courts' lead and find
that ProgressOhio has no standing.
"Additionally, it continues to be beyond our understanding why anyone would fight against job
creation when it's so important to Ohio and our continued economic recovery," Wehrkamp said.


text:
Academic Writing Symposium, Chapter 16
Description not set
[Panel Discussion] Discussion and Draft Recommendation
iDASH Privacy Workshop 2011
October 10-11, 2011
Discussion led by Wendy Chapman, UCSD
Tornado Video
Ellis Island: Island of Hope - Island of Tears
A Well-made National Park Service film. From 1892-1954, Ellis Island was the port of entry for millions of European immigrants. Fascinating archival footage tells the moving story of families with dreams of opportunity, leaving their homes with what they could carry. (29min)
Women's Basketball Worst Movies
Meet the 2011 Women's Basketball team and discover their least favorite films.
Women's Basketball Meet the Players 2011
Meet Armstrong Atlantic State University's Women's Basketball team.
OCW Consortium Small
OCW Consortium
Chicago History Episode 3
Chicago History dives into the event that changed Chicago forever, The Great Chicago Fire in this eight minute video. The video stresses how the fire enabled Chicago to rebuild and reorganize after the event.
Jane Addams and Hull House
This student made video presents a brief biography of Addam's life as it relates to the Hull House using original photos. It does not tell what was happening in the nation at this time, but alludes to her other accomplishments and Nobel award.
SPLASH 2011: Andrew Black and James Noble - The Grace Programming Language Project The Grace Programming Language project is a research effort that aims to make learning how to program easier by baking "educational abstractions" into the language itself - it's an object oriented programming language designed for teaching undergraduate students. This means the language is designed from the ground up as a learning tool for novice adult programmers.
The Grace PL project is led by
Pope Benedict arrives in Africa
Nov. 18 - Pope Benedict called for religious tolerance as he arrived in Benin, the cradle of Voodoo in West Africa. Deborah Gembara reports.
Frank and Jesse James
This episode of Stories of the Century has railroad detective Matt Clark tracking down notorious brothers and bank robbers, Frank and Jesse James. (26min)
Robin Williams is cool with Penguins.
Nov. 13 - Robin Williams plays it clean when it comes to the family film, "Happy Feet Two."
Female martyrs honored in Yemen
Nov. 18 - Yemeni protesters say the death of female opposition members will not be in vain as they called for President Ali Abdullah Saleh to step down. Deborah Gembara reports.
North Carolina Women and the Progressive Movement
This lesson includes primary sources from Documenting the American South specifically related to North Carolina women involved in reform movements characteristic of the Progressive era. For the most part, these documents detail women's work in education-related reform and describe the creation of schools for women in the state. They also demonstrate that, as was true in the rest of the nation, the progressive, female reformers of N.C. were segregated based on race and socio-economic status.
Great Zoom Mosaic - Zoom Out
This is a mosaic of zooms out of 20 different locations prepared to support a paper given at IEEE Visualization 2002. The locations are: Long Beach, CA; New York City, NY; San Fransisco, CA; NASA-Goddard, Boston, MA; New Orleans, LA, Salt Lake City, UT; Sabie River, Africa; Park City, UT, Chicago, IL; Mongu, Africa; Salt Lake City, UT; Amazon, Brazil; Los Angeles, CA; Baltimore, MD; Snow Basin, UT; Atlanta, GA; Washington, DC; Orlando, FL; and Seattle, WA. Using data from different spacecraft an
Nothing magical about 7 pct yield level - Mizuho analyst
Nov. 14 - Investors are overly fixated on keeping Italian yields below 7 pct, says Mizuho Corporate Bank's Nicole Elliott, who argues that emerging market bonds prove there's nothing magical about that level.
Legend Hunters
ECU's Maritime Studies program finds a cannon from Blackbeard's flagship the Queen Anne's Revenge. The QAR Project is managed by the North Carolina Department
of Cultural Resources in partnership with East Carolina University.
The recovery operation of Cannon 13 was supervised
by the Office of State Archaeology -- Underwater Branch
in partnership with the NC DENR Marine Fisheries,
NC State Ports -- Morehead City, NOAA, and the Town of Beaufort.
Many of the restored artifacts from the QA
Perspective from Daktari
Description not set
Mises en voix de quelques textes d'Adolphe Pacault
Mises en voix de quelques textes d'A. Pacault :
- A. Pacault. Débat Dominique Lecourt et Adolphe Pacault. In :Du feu. Hachette
- A. Pacault. Mémoire d'une histoire. Bulletin d'Information du CRPP, 2000, n°176
- A. Pacault. La tentation de l'homogène. Boîte aux lettres


text:
Twitter prices IPO shares at $26
Twitter and its bankers set the price for its IPO at $26 per share this afternoon, with everything set for shares of TWTR to begin trading tomorrow on the New York Stock Exchange. It's the most anticipated -- and hyped? -- IPO since Facebook went public in May 2012.
And Twitter execs hope the comparisons to Facebook's IPO, which was met by eager sellers and technical glitches, ends there.
Twitter tweeted the share-price news this afternoon. It's offering the public 70 million shares, which would value the company at $14.2 billion. It's raising $1.82 … Read more


text:
We were here 2 couples one week ago and stayed for 5 days. The hotel is on the east side of Railay, the part with mangroves, so no beach here. But to the west side where you can lay on the sun is only a 7 minutes breathtaking road under rocks and caves. The stuff is very friendly and helping... More
- Also Known As:
- Sunrise Tropical Hotel Railay Beach
- Sunrise Tropical Hotel
- Sunrise Tropical Krabi
- Sunrise Tropical Resort Railay Beach, Krabi
- Official Description (provided by the hotel):
- Sunrise Tropical Resort, an exclusive resort on Railay East Beach. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Agoda, Priceline, Otel and HotelTravel.com so you can book your Sunrise Tropical Resort reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.


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[7 Posts]
Skeleton Creek would probably be on the list as well with Kathy's Book.
Posted: Fri Feb 13, 2009 10:12 pm
This should also help. 10-minute experience, quite awesome.
Eagle Eye Freefall
Other things that would give you the kind of experience you're looking for:
Cathy's Book
Cathy's Key
, and (soon)
Personal Effects Dark Art
for book-based experiences.
That's all I can think of off the top of my head.
Posted: Fri Feb 13, 2009 11:22 am
B__Lukey, I wish you luck.
Part of the charm of ARGs is that they almost always rely on community interaction and collaboration as a part of its narrative development and discovery.
So, while I will not say that an ARG such as you seek is not possible/hasn't happened/is not findable, the single-play model isn't always extant on the web (see Jamie Kane:
), or in complete, playable form (see The Beast:
There have been some attempts to archive major pieces of some of these ARGs (like Arghive), but over time it's become apparent that whatever trademarks this genre happens to include, real-time community development is a huge part of the process.
So, having said that, and feel free to disregard this next bit: my advice to you is to refrain from thinking of threads here at the Unforums as 'cheating.' In fact, web search engines like Google are your friends, and using wikis, trails/guides, and other resources are there just for the purpose you describe. These experiences are not generally meant to be 'solved' or discovered by one person: there is often so much disparate information wrapped up in the narrative in so many different ways that it pretty much requires a collective to work together and eke out greater meanings.
But! I still wish you luck.
I think you can jump right into This Is My Milwaukee right now, in my opinion, and you might even be a hero, because it looks like we're still missing a piece or two of the puzzle that might move us forward in the narrative. So, come on over whenever you like!
Posted: Fri Feb 13, 2009 9:55 am
I could be wrong and there could be some out there, but due to the nature of many ARGs, I imagine you might have some difficulty in finding one that wouldn't require you to receive e-mails/chats when they were originally sent out or be involved when certain events unfolded.
Posted: Fri Feb 13, 2009 9:44 am
Maybe..... i'll have a look once i'm home.
Ill try and explain more clearly.
What I want is to be able to start an established game from the trailhead and have the same experience that someone who has been playing for months had.
Example: I had a look at
this is my milwaukee
and it appears somewhere near the begining people received faxes.... now I imagine if I played it as if i was the only one to discover that trailhead I wont receive a fax... forcing me to rely on other peoples experiences. It seems alot of games have certain
points of no return
where you cannot start playin before those points in the game.
Thanks for the reccomendation. Will look into it.
Posted: Fri Feb 13, 2009 8:28 am
You could try Eldritch Errors. We're at a sort of lull-- we just finished the third part of the ARG, so we are taking a break. You can catch up by reading various manuals and things that you can find in the EE forum.
Is that the sort of thing you're looking for?
Posted: Fri Feb 13, 2009 6:30 am
Looking for a helping hand
Hi all.
I'm looking for help finding an ARG. I know, I know.... I can already see you have heard this before. But I have looked through the helpful threads for picking an ARG. And they are helpful. So I decided to look at some threads of some games, aswell as trying to get in on a couple just starting up.
Problem is, from what I've seen, alot of these decent ARGs have alot of character interaction or drop offs, etc. In a game that is currently running that is cool, but I would like to play an established game that started a while ago that I can catch up with everyone else by playing it myself without having to read through a load of posts. With things like the drop offs I mentioned earlier in the post and other things, it seems that once I got to that point of the game.... I would have no alternative but to come on to this site and 'cheat'.
I hope you get what i'm trying to say. I did put this more clearly last night but forgot to submit my post, but now I'm slightly hungover at work and can't seem to think straight.
Basicly.... Can you recommend me a game (finished or currently running but well established) which I can play from start to finish (or current situation) without having to come on this site and read about the game, rather than playing it?
Thanks for any replies and thanks for trying to make sense of my rambling.
Posted: Fri Feb 13, 2009 5:18 am
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The subject of intentional breeding or meat rabbits is prohibited. The answers provided on this board are for general guideline purposes only. The information is not intended to diagnose or treat your pet. It is your responsibility to assess the information being given and seek professional advice/second opinion from your veterinarian and/or qualified behaviorist.
LEADERS: Beka27 BinkyBunny Elrohwen KokaneeandKahlua LittlePuffyTail MoveDiagonally RabbitPam Sarita
so if you read my previous thread: i got the holland lop. the woman seemed nice but insisted that "the rabbit should be fine" when i asked if it was okay if i emailed her if she got sick. but other than that she seemed friendly.
but now i feel like i made some horrid mistake! i feel really bad for my other rabbit! he is SUCH a sweetheart, and i dont want that to change! he loves to flop near me/ next to me and begs for pets all the time, i really dont want that to change with the new rabbit! ugh before i got her i thought "oh my current rabbit will like having a bunny friend" and ugh i just dont want him to change! BUT HERE IS THE OTHER THING: before i adopted him he lived in a foster home with other rabbits but i dont think they were bonded? so i dont know how he will act when he has an actual bonded bunny friend i feel selfish! i am selfish, but im really protective over my pets, and i want them to be as happy as possible but i also want them to be the same
also, the rabbit seems awfully small for 7 weeks, if you think you can tell me around what age she is i will post a picture! i mean i have never seen a baby rabbit before in real life, ever LOL except once at a pet store but it was like for 30 seconds. and they were all different breeds. and i will take her to the vet for a checkup but i have some concerns:
1) there is a small red dot (almost like a scab) in the corner of her left eye, at first i thought it was slight discharge but it is a tiny scab, i thought maybe she scratched herself? her nails were EXTREMELY sharp, but i clipped them all right when i got home. but the scab is like the size of a needle point
2) i was feeling around on her body for ticks or anything (her ears and the rest of her body seems free of mites and insects and no discharge from the eyes or nose and teeth look normal and there is no poo stuck to her bottom or anything) and there was a small hard bump on the back of her neck so i thought it was a tick but i looked and i didnt see anything but i saw s weird scab? its not big but yeah.
also her skin seems kind of flaky, just a little. is that normal? i will include pictures of her eye, neck (so you can see the bump) and just her fur parted so you can barely see the skin flakes.
(i will add the pictures as a reply)
sorry its sideways im actually surprised i know how to upload a picture LOL anyway so the quality stinks cause the picture has to be 500KB or less but you get the idea! there's the red dot near its eye
there is the small dot on it's neck - ignore my gross fingers/nails
and there is its skin - it doesnt look THAT flaky i think it looks normal, but there are very few flakes in the skin and i dont know if that's normal or not - you cant really see them but yeah
This is at about 3 days old.
This is about 2 weeks. That's a seeding try they are in.
Same tray at 3 weeks
This is about 4-5 weeks.. You can see their ears developing and setting upright where as babies the ears were still floppy things that tended to stay close to their heads.Unless they are lops then you might start to see the ears beginning to drop.
I am trying to select pictures that give you some scale of growth and development. For other members it's tempting to Ooh and Aah over these pics but seriously, you do not want to go through the stress of an oops litter. Don't even be tempted to "just have one".
It's not worth it! Aside from the stress there is the expense of food etc. They eat like Trojans and Pepper trebled her food intake to keep up her milk production, not to mention vet costs, accommodation and the rest.
Coming up to 7 weeks, note the development in the ears again. Fully formed and upright. A lops ears would almost be completely dropped.
Nine weeks
Finally at 12 weeks. Both girls are now mid sized and slightly bigger than their mother Pepper. You can see them in the November Photo Thread, Blossom is sitting on the top shelf by the window and Pepper is right down the bottom on the floor under the shelves.
Hope this helps.... I will only leave it a few days then delete it as we have strict forum rules about posting baby bunny pics.
sorry most are sideways! and i made a ghetto litter box out of a cardboard box LOL just for tonight!
She is adorable!. She doesn't look younger than 7 weeks to me. Having her in your room where it's quiet and safe feeling for her is good, however, your other bunny may have the natural reaction of wanting to defend his territory since this is not a neutral zone. So he could start marking. Some bunnies may even get agitated or aggressive toward you temporarily. It's not really against YOU, but the scent of another bunny may trigger that reaction. But if that dies down and doesn't worsen, then allowing them to just get used to each other's scent and seeing each other even if they don't get in contact may be a good. You do have to be careful of them being able to bite each other if they can come in contact with each other through cage bars. (depends on how big the cage bar spacing is). But rabbits can do damage to each other's face through bars if they decide they don't like each other right away. So just keep an eye on that.
Keep us updated!


text:
Jean-Eric Vergne is adamant he could replace Mark Webber next season despite not been given a Red Bull run during the recent Young Driver Test.
While Vergne was left out in the cold, Ricciardo spent half of Thursday putting in laps at the Silverstone circuit behind the wheel of Red Bull's RB9.
The brief test put the Australian at the head of the list to replace Webber next season should Red Bull fail in their bid to sign Kimi Raikkonen from Lotus.
In fact such is Ricciardo's lead over his team-mate Vergne, that team boss Christian Horner recently conceded to Sky Sports News that it is "probably" a two-horse race between the Aussie and Raikkonen.
Vergne, however, insists he's not giving up and believes he still has a chance of making the step from Toro Rosso to Red Bull.
"I still believe in my chances," the Frenchman told Autosport. "There is of course a chance. I would love to drive for Red Bull.
"But so far it makes no sense for me to think about it. It won't help me."
As for his team-mate's Red Bull test, he said: "It's been a big story for him of course. It's normal.
"I don't want to think about anything for next year, any chance that I could go to Red Bull Racing whatsoever.
"You lose focus, and you lose some energy, so I want to keep it all for this year with Toro Rosso."
However, should Red Bull opt for someone other than him to replace Webber, Vergne hopes they will pick his current team-mate as this would also look good for him.
"If they have made their mind up that it should be between Daniel and Raikkonen, I would definitely prefer Daniel to go there.
"That is quite good for me because I can beat him. I did it this year when I didn't have problems.
"Then I just have to show the right people that it was not a one-off."


text:
Backpacker Magazine – March 2010
Cross the steeps safely and avoid avalanches with these guide-approved tips.
Stop Any Fall with Self-Arrest
On gentle slopes, head straight down instead of traversing diagonally, says Councell. On steep descents, switchback down, plunging your heels into the snow in a rhythm and keeping your knees slightly bent. Hold your axe in the uphill hand and plant the shaft for balance and self-belay.
Feet first on your back Hold the axe diagonally across your chest—one hand gripping the shaft and the other gripping the head, near your ear. Roll toward the pick and flip onto your stomach. Press all of your weight onto the pick to dig it into the snow and kick your toes into the slope to stop.
Headfirst on your stomach Reach forward and to the side and dig the pick into the snow. Pivot around the axe head and dig in with your toes.
Headfirst on your back Dig the pick into the snow at your hip. Twist onto your stomach and let your legs swing around to get in position to stop.
Most important of all - if you think that you need this info, be sure to get out and PRACTICE in a save spot before it is a matter of your safety! Many local climbing clubs have basic ice and snow safety training. "Think ahead to keep your head."
Beware spring melt stream tunneling under snow pack. Can fall thru "snow bridge". If shallow your wet, if deep you've got trouble.
It would be sporting to mention the hazard of loosing control of the ice ax and have the pick flailing as wildly as tho one out of control. Not that I would know. TK


text:
Phoenix Tempe Hotels + Gay Friendly + CANDLEWOOD SUITES
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"The room was fairly inexpensive, but you get what you pay for. The bedspread had hol... Read more"
Note: The nightly rates shown above do not yet include Tax Recovery Charge & Service Fees or (if applicable) Extra Person Fees, Child Fees, Additional Mandatory Hotel Charges or optional incidentals, such as parking, room service or movies.


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Metallic Crinkle Skirt
So Versatile
I purchased the gold skirt (in petite large) to wear with a dressy safari jacket that has a touch of gold sheen in the fabric. It is great together, but the skirt also works well with a wide variety of dressy tee shirts. For information on length - I found that a 32" half slip works well underneath. I am 5'6" and the hem falls at mid calf.
November 11, 2013
Perfect for the occasion!
I purchased this metallic skirt in gold for a beach wedding I went to in Florida. Not only does it match perfectly with two of my tops, it stores in a BAG! Perfect for traveling!
It was just the right outfit for the occasion!
November 11, 2013
Pretty, shiny skirt, fabric so so quality
The blue color is beautiful, and it shines a lot either under the sun or night lights. It pairs very well with black and white tops; aqua green too. It can be dressed up or down, depending on the circumstances. Looks pretty, but the fabric is polyester of not very good quality; tends to be hot. Were it not for these last shortcomings, and a somewhat high price, I would rate it 5 stars.
October 29, 2013
worth the purchase
No complants with regard to the skirt except for the length; just a little too long for someone 5'4" but overall a great outfit that I purchased as pictured and had many compliments.
October 24, 2013
travel necessity
This will be great for those trips when a skirt like this is dressy or casual as the top worn with it. Also planning to wear for holiday parties. I always pack at least one crinkle/broomstick skirt for "just in case". This will go with the Fiesta skirt I got 2 years ago.
October 14, 2013
Great Skirt!
I bought this skirt in the Champagne color in the Spring of 2012, and I took it to Thailand, where I wore it at least twice each week for fourteen months. Everyone there complimented it, and many local Thai people thought it was Thai silk. I almost wore it out, so I just purchased two more:: one in the Champagne color and one in the Sapphire Blue color. When I wear them, everyone loves them, including me!! These skirts are comfortable, go with so many tops, have the beauty of silk, are versatile and great durability.
October 2, 2013
quite pretty
The skirt fits well, looks pretty, and is quite comfortable. My only issue was finding a top that goes well with the skirt.
July 27, 2013
I couldn't believe how nice this skirt looked when I took it, rolled up, out of the cloth bag it came in. Have not washed it yet--but expect it will do beautifully.
July 8, 2013


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To study the molecular mechanism by which nonmuscle myosin II (MII) regulates protrusion and adhesion dynamics in migrating cells, NIH3T3 cells were transfected with myc-tagged phosphomimetic constitutively active MLC mutants (MLCee, green) and co-stained for TRIO (a multifunctional, multidomain Rho guanine nucleotide exchange factor, red) and filamentous actin (blue). These findings help elucidate a functional link between MII and Rac1/Cdc42 GTPases, which may regulate protrusion/adhesion dynamics in migrating cells. This image is original data from Fig. S5 "Expression of active MLC mutants inhibits the dissociation of MII�Trio complex," in J. Cell Biol. 2010. Vol. 190(4):663�674
Technical Details
Cells were cultured in DME (Invitrogen) supplemented with 10% fetal bovine serum and 100 U/ml penicillin/streptomycin (Invitrogen) at 37°C in a humidified 5% CO2 incubator. For transfections, cells in 60-mm-diameter dishes or on fibronectin-coated coverslips were incu- bated with a mixture of DNA and LipofectAMINE 2000 (Invitrogen) according to the manufacturer's instructions. The cDNA for MLC was subcloned into pCMV-myc (Takara Bio Inc.). Mutant constructs of MLC were generated using a QuikChange site-directed mutagenesis kit (Agilent Technologies) according to the manufacturer's protocol. In this myc-tagged MLC mutant, Thr18/Ser19 were replaced by glutamic acids, and expressed in NIH3T3 cells. In some experimental conditions, 16 h after replating onto fibronectin-coated coverslips, cells were treated with 50 ng/ml PDGF for 20 min. Cells were fixed 24â��48 h after transfection using 3.7% paraformaldehyde in PBS for 15 min, permeabilized using 0.2% Triton X-100 in PBS for 2 min, blocked with 2% BSA in PBS, and co-stained for MLC (green), TRIO (red), and actin (blue). Images were captured by Zeiss LSM 710 confocal microscope with Plan-Apochromat 63X objective.
Biological Sources
- NCBI Organism Classification
- Mus musculus
- (house mouse)
- Cell Type
- fibroblast
- Cell Line
- Cellular Component
- lamellipodium
- myosin II complex
- actin filament
Biological Context
- Biological Process
- regulation of cell migration
- Names
- Chan-Soo Lee
- Chang-Ki Choi
- Eun-Young Shin
- Martin Alexander Schwartz
- Eung-Gook Kim
- Published
- J. Cell Biol. 2010. Vol. 190(4):663�674
- Link
- http://jcb-dataviewer.rupress.org/jcb/...
- Pubmed
- 20713598
This image is part of a group.Imaging
- Image Type
- recorded image
- Imaging Mode
- confocal microscopy
- Parameters Imaged
- fluorescence emission
- Source of Contrast
- distribution of epitope
- distribution of a specific protein
- Visualization Methods
- Alexa Fluor 488
- Alexa Fluor 546
- phalloidin
- Data Qualifiers
- raw, unprocessed data
Sample Preparation
- Methods
- formaldehyde fixed tissue
- detergent permeabilized
- Relation To Intact Cell
- dispersed cells in vitro
Spatial Axis | Image Size | Pixel Size |
X | 512px | —— |
Y | 500px | —— |


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Mothering › Mothering Forums › Natural Living › The Mindful Home › Arts & Crafts › Books, Music, and Media
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text:
Mendocino College is seeking qualified bidders for its Measure W bond-funded North County Center project in Willits. A formal Notice Inviting Bids has been issued by the college governing board announcing details of the bidding process and the bid deadline of 1 p.m. on July 25.
With a projected construction cost of approximately $4 million, the new college center in Willits will feature three classrooms, a computer lab, a learning commons, group study rooms, admissions and registration center, faculty and staff offices and more.
Located on four acres of college-owned property at the northwest corner of East Commercial and North Lenore Streets in Willits, the new center is projected for completion in time for the start of the spring semester in January 2014.
In addition to construction of the center facility, the project also includes development of a parking lot, landscaping, courtyard, and facility access improvements along East Commercial Street.
A mandatory bidders' conference will be held at the project site, 300 E. Commercial St. in Willits, on July 10 at 1 p.m. for the purpose of acquainting all prospective bidders with contract documents and the project site. For more information about the bidding process, contact the Mendocino College office of Facilities Planning at 467-1028.
The Willits project is funded by the Measure W Bond, approved by voters in Mendocino and Lake counties in 2006.
The bond has already provided funding for the new college Library and Learning Center set to open this fall on the main campus in Ukiah; Lake Center in the city of Lakeport, scheduled for completion at the end of the year; and several other major construction and equipment acquisition projects designed to improve college programs and services.


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Love-and-nature.com: 'The cutest hotel in Amsterdam'
The rough Guide: 'Extremely pleasant hotel...'
From: Lonely Planet Amsterdam city guide by Andrew Bender
Dutch Modern furnishing meets 17th century canal house setting at this quiet and understaded spot. Its eight comfortable, individual rooms all have canal or (upscale) neighborhood views and the top-floor rooms have loads of light. The staff is very accommodating.
From: Time out guide 'Amsterdam' issued by Penguin books
There is more to this bolt-hole than the prosaic name implies. Run with tons of tender loving care by the charmingly scatty owners, rooms are furnished in glamorous but understated '30s style, you will be glad to know ta they are all a good size. Room eight, up among the eaves, sleeps up to five - two of the beds are on a lovely mezzanine.
From: Wallpaper City Guide 'Amsterdam' issued by Phaidon
Hidden in a typical Amsterdam canal house. 't Hotel is one of the city's best b&b's. Three of the eight rooms overlook the impossible romantic Leliegracht, which runs perpendicular to the main canals of Keizersgracht and Herengracht. Room 8 on the top floor is a huge loft space that sleeps up to five. It has glorious views of the immaculate courtyards gardens next door.
www.travelintelligence.com: "The beds are so comfortable often guests want to know where to buy them. . The style is modern with touches of the elegance of the Thirties and the hotel has a very homely atmosphere. ..the breakfast buffet is varied and generous – among the best in Amsterdam. ..The excellent rates .. makes this one of the best choices in this price range.' (no wonder they selected us for their list!).
Reviews from guests
- 62 reviews of 't Hotel in Amsterdam


text:
Cycling Map Applications and Mileage Trackers
4 Awesome Map Apps for Cyclists
Map My Ride
Go for a ride anywhere
With a database of millions of routes, MAPMYRIDE can find a premapped ride in almost any location on the planet. Record new routes as you pedal, analyze ride data, then share it on Facebook and Twitter. The app syncs with fitness devices via ANT+ technology (available for iPhone and some Android versions).
Cost: Free
Works On: iPhone, Android, Blackberry
More Info: MapMyRide.com
Video: Learn to get your wheels dirty with Mountain Biking 101
. Then take your bike on your next trip and explore one of America's Most Bike-Friendly Cities.


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(AP) -- JEFFERSON CITY, Mo. (AP) -- Missouri's Department of Conservation says hunters took nearly 205,000 deer during November's 11-day firearms season. That's the highest number in four years and 7.7 percent higher than last year.
Wednesday's report says the figures bear out earlier predictions for a big hunt in southern Missouri. Scientists had said a poor acorn crop was forcing deer to concentrate in places where acorns were plentiful.
Eight of the 10 highest-performing counties were south of the Missouri River, led by Howell County with 4,037 deer bagged. Texas and Benton counties were next.
Firearms season began November 10th and ended Tuesday. The department says does (dohz) accounted for roughly 44 percent all deer bagged. The number of antlered bucks taken was up by more than 6 percent.
(Copyright ©2012 by The Associated Press. All Rights Reserved.)


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This post presents 10 shortcuts to Google Analytics reports and dashboards for publishers, bloggers and content marketers.
I've compiled these from various sources, but I'm sure there'll be some more useful reports out there, so please share them in the comments...
If you are logged into your Google Analytics, just click the download links, and the reports and dashboards can be saved to your acount.
Read more...
by Graham Charlton 09 September 2013 12:53pm 4 comments
For the second year in a row 50% of businesses have cited lack of resource and budget as the main barrier to implementing a successful online measurement strategy.
The second most common reasons were siloed organisation/lack of co-ordination and lack of strategy, both of which were identified by 25% of respondents.
The findings come from the Econsultancy/Lynchpin Online Measurement and Strategy Report 2013 which contains a comprehensive analysis of issues affecting the web analytics industry and valuable insights into the use of analytics and business intelligence tools.
by David Moth 15 August 2013 13:20pm 0 comments
A recent article on the Econsultancy blog discussed the issue of page load times getting slower with some helpful tips on what can be done to help speed things up.
The article stimulates other questions that I thought it would be interesting to tackle in more depth.
by Greg Randall 07 August 2013 09:28am 16 comments
Many SEOs spend a lot of time trying to improve rankings for non-branded search terms, for all sorts of reasons. We do this too, but I've always kept a very close eye on branded search volume.
When we launched this blog in 2006 one of our primary aims was to improve our overall share of search. Another was to move the key brand metrics in a favourable way, not least because a visitor who adds 'Econsultancy' to a search term is 8-12 times more valuable than somebody who doesn't include our brand in their query.
As such, branded search traffic is very important to us, but the horror show that is 'Not Provided' means that it is increasingly hard to track it. In fact, you will be appalled if you only look at your analytics data.
With this in mind, I thought I'd show you our numbers, and provide a workaround for you to try.
by Chris Lake 24 July 2013 12:30pm 15 comments
Here are some of the most interesting digital marketing stats we've seen this week.
Stats include the best features to include in mobile apps, marketing budgets, mobile search, Google Analytics and the rise of Google+.
For more digital marketing stats, check out our Internet Statistics Compendium.
by David Moth 12 July 2013 12:08pm 4 comments
More than half of businesses rely exclusively on Google Analytics (GA) for their web analytics while just 11% don't use the tool at all, according to data included in the new Econsultancy/Lynchpin Online Measurement and Strategy Report 2013.
This is a massive increase since 2009 when just 23% of respondents said they used GA exclusively.
With GA having a reputation as both free and easy to use, and having a strong community around getting the most out of the tool, it is no surprise to see the majority use it.
The increase since 2011 could, however, be partly due to the discontinuation of Yahoo's free analytics tool, which was used by 8% of companies and 18% of agencies last year.
by David Moth 09 July 2013 11:24am 16 comments
A bit of customisation always helps if you want to extract maximum value from Google Analytics.
Custom reports are a great way to do this, but custom dashboards also play a useful role, allowing you to view key metrics at a glance and tailor the view to your own needs.
Here I've rounded up 10 custom GA dashboards from various sources.
Just click on the link under the screenshots to automatically add these to your Google Analytics profile...
by Graham Charlton 30 May 2013 11:11am 22 comments
At Google's annual I/O developer conference, an important new feature to Google Analytics was announced that's going to turn mobile marketing on its head.
Built on the back of the new Universal Analytics platform and its baked-in ability to track users across sessions and devices, Cross Device Measurement is like Multi-Channel Funnels for devices.
And it's huge....
by Damion Brown 20 May 2013 11:41am 13 comments
My last article detailed the benefits of focusing on website analytics specifically around site search data.
This article continues with the same theme of valuing website analytics, but the focus turns to unbranded keyword traffic.
In the context of reviewing analytics, "unbranded keywords" are those words/phrases not containing the retailer's name.
People who type "Apple iPod Nano" into Google and land on the JB Hifi website is an unbranded keyword phrase from the perspective of JB Hifi. The keyword phrase "JB Hifi" is a branded term for this retailer.
Understanding the dichotomy between branded and unbranded keyword phrases is necessary in order to effectively assess site performance and build a focused plan for growth.
by Greg Randall 30 April 2013 13:46pm 2 comments
Along with custom reports (and sometiimes in conjunction with them), custom advanced segments are a great way of gaining extra insight and value from your Google Analytics account.
In this post, I'll round up ten very useful custom segments that you can import straight into your GA account, and save yourself the trouble of creating them yourself.
Please suggest any other segments you find useful in the comments...
by Graham Charlton 16 April 2013 11:37am 10 comments


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rag & bone/JEAN
The Skinny
Rag & Bone was born in 2001 through the shared frustrations of not being able to find the type of clothing everyone wanted to wear. With all manufacturing done in America this brings all the history and skill to each individual piece more to life. Unique and set apart these pieces were made to be.
- Wash - Destroyed
- 30" Inseam
- 8" Rise
- 98% cotton 2% polyurethane
- 12" in the knee narrows to 10" at the leg opening
- Whiskering along front pockets
- Fading along front of pant and back pockets
- Distressing throughout
- Styled with Steven Akcess Pump in Taupe Nubuck.
- Styled with Dream Collective Giza Ring in Gold Plated.
- Styled with Front Row x Luv AJ The Tusk Ring in Gold.
- Styled with CC Skye Double Header Spike Bracelet in Rose Gold.
- Styled with House of Harlow Pave Safety Pin Wrap Ring in Gold.
- Modeled in size 27. See fit guide for model's dimensions.
- Revolve Style No. RAGA-WJ52
- Manufacturer Style No. W1502K520
- Can't find your size? Place a special order inquiry for this item.
Some Curves/Average Height
Just want to advise people not to size up with these. I debated between a 26 and 27 and decided to get the 26. I'm always a 26 in j brand, james etc but I'd heard rag and bone ran small. Definitely not. I wish i'd gotten a 25. They run a size bigger than j brand, very stretchy. They're still cool but just wished they were a little more fitted.


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Kathmandu, May 11:
Editor-in-Chief of Gorkhapatra daily Sitaram Agrahari has been designated as acting General Manager of Gorkhapatra Corporation.
A ministerial level meeting of the government took this decision on Friday. The decision authorises Agrahari to exercise the corporations executive rights and carry out financial and administrative activities.
The government has terminated executive rights being exercised by current Chairman of the corporation Ram Kishor Singh.
The government has also decided to send current acting General Manager Kapil Ghimire to his previous post of managing editor. GM Agrahari entered the corporation as a sub editor in Jestha 2045 BS. He has been serving as Editor-in-Chief of Gorkhapatra daily since 5th of Baisakh 2068 BS.
Agrahari is a BA Honours in Political Science and has received Diploma in Development Journalism from Indian Institute of Mass Communications in New Delhi, India.


text:
Check out this exclusive feature from the September issue of …
Check out this exclusive feature from the September issue of Drag Racer magazine–on sale now! Let it be known, whether you buy a hard part or vehicle seat from Scat, you're doing business with Tom Lieb, a certified car guy, not some (Read More..)FEATURED ARTICLES
Don Lough's Bubble Top Beauty
One of the greatest parts of goin' to the digs isn't just the racing, but the car show, too! One of the sweetest rides you're going to come across is (Read more...)
Behind the Scenes of Snake and Mon
Winner's circle of the '78 U.S. Nationals. Top row (L to R) Dennis Tracy, Crew Chief Pat Galvin, unknown, Tom McEwen, unknown, Wally Parks. Bottom row (L to R) (Read more...)


text:
I came out as a bi sexual, but I think over time and still now I am becoming more and more lesbian. I feel more comfortable with other women than men, I don't know why though. I suppose it because most of my more successful relationships were with women =3.
2 replies to this topic
This, I can understand. I came out when I was sixteen or so as bisexual, but then I realized "Nuh uh, full on lesbian in the house", hence I came out as lesbian when I was seventeen. Besides, we women can understand each other better than men can understand us. Anyway, just be comfortable with who you are and love who you want. You only live once! : )
Stick around for the ride. You'll never know what happens.
Technically, I came out as lesbian in 4th grade to my best friend/biggest crush, 30 minutes later re-closeted, came out as bi curious in 7th grade, full bi in my second 9th grade, went to college, became the slut of the school, went to a shrink, and came out again as a lesbian again. The map to my life was handed to me on a silver platter at a rather early age, and christian fundamentalist views told me the vegetables on that platter were bad for me as it was slapped out of my hands and my fragile, childhood psyche shattered in half an hour. I know that because that's how long morning recess was. Either way, therapy works and I love who I am now. That's more what matters than anything else.
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text:
Aug. 28, 2007 at 8:00 AM ET
A group of computer security researchers in Israel and Belgium say they've discovered the electronic equivalent of a Slim Jim -- a way to pop the electronic door locks on most cars without ever touching them.
Drivers don't have to worry about their cars being hacked just yet – a baseball bat is still a more effective auto theft tool – but the announcement shows yet again that newfangled security devices can be more vulnerable than you think.
Most modern cars are now equipped with convenient remote keyless entry systems. Now it seems that tool could be a convenient way for criminals to break into hundreds of cars in an afternoon.
By listening in on the wireless "conversation" between a car and its key, the researchers found they could crack the code that keeps the communication secret. Then they were able to emulate the electronic key and trick the car into unlocking itself.
Nearly all cars with remote keyless entry use an encryption system called KeeLoq. It was developed during the 1980s and purchased by Microchip Technology Inc. in the 1990s. Like all encryption systems, KeeLoq scrambles messages so they can't be read by anyone who intercepts them. Only someone -- or something -- with the appropriate deciphering key can unscramble the message.
Eli Biham, a computer science professor at the Technion-Israel Institute of Technology, says there are 18 billion possible keys for a KeeLoq transmission, making it practically impossible for even the fastest computer to work out the key through brute force.
"But," he said, "we found a shortcut."
By intercepting several transmissions from the electronic key and analyzing them, Biham and his colleagues say they were able to eliminate many of those 18 billion possibilities and work out a master key in about one day. All that's required is remote access to one key for about an hour -- say, while a person is sitting in his office with the key still in a shirt pocket.
Then, after working out the encryption scheme, Biham's group says it can unlock all cars using that master key within a few minutes.
"In modern ciphers, you don't expect this to happen," Biham says, noting that carmakers are still relying on 20-year-old cryptography to keep cars safe. "I don't understand how companies sell cryptography from the 1980s."
'Badly broken'
The research paper, called "How to Steal Cars, (PDF)" was presented at the Crypto 2007 conference at the University of California, Santa Barbara, last week. Exact details for exploiting the discovery won't be published for several months, Biham says, but Microchip Technology was informed weeks ago.
"KeeLoq is badly broken," the paper says, adding, tongue-in-cheek, "Soon, cryptographers will all drive expensive cars."
Microchip wouldn't comment on the team's discovery.
"Microchip Technology Inc. doesn't address matters of security in the public domain," was all that spokesman Eric Lawson would say.
But other cryptography experts said the research was significant.
"This is a very practical application of cryptanalysis," said Jon Callas, chief technology officer with the encryption firm PGP Corp., who attended the presentation. "There is a larger lesson here, which is some of these devices aren't as secure as they are being sold to us."
Slim Jim a bigger threat
Still Callas isn't worried about his car locks being hacked just yet. There are several barriers to using the technology. While a key hacker would be able to pop the lock on the door and perhaps disarm and alarm, he or she probably couldn't get the car started without using old-fashioned car theft tools, he said. And even with the most sophisticated computers, hacking the locks still takes over an hour, while a baseball bat can do just as good a job in a second or two.
"There is not a whole lot of threat to the end consumer," he said. "A guy with a Slim Jim is a bigger threat."
The method could prove lucrative under the right circumstances, however. A thief armed with a master key could park a car with listening devices in the middle of a shopping mall lot and eavesdrop on every car as a driver parks, walks away, and pushes their key to lock the doors. Within seconds, the transmission could be intercepted, analyzed, paired with information about a known master key and used to pop the locks. A criminal could theoretically open hundreds of cars each day that way, stealing a treasure trove of iPods and GPS gadgets without leaving a trace
"That would be worth someone's time," Callas said. Victims "would have a hard time convincing (their) insurance companies that this had happened."
A simple fix
Modest adjustments to encryption tools would foil such a plot, Callas said. Biham's method requires tricking the car's system into answers a long series of questions. But the use of "throttling" -- inserting a delay after every three requests, as some Web sites now do – can slow or eliminate such brute force attacks. So Callas has no plans to disable his electronic locks, which could be done by disconnecting the car's battery while parked.
"I'm more concerned about losing my radio presets than having my car stolen like this," he joked.
Intense research into Keeloq by several groups began last year after proprietary information about KeeLoq's cryptography was leaked onto a Russian Web site. Biham said the information aided his group's research, but argued that properly implemented cryptography should withstand publication of such details.
Both he and Callas were critical of Microchip for not publishing its cryptographic scheme in public earlier, which would have allowed researches to probe it for holes.
"Those of us who are in the field believe that algorithms should be published from the start because an analysis can strengthen them," Callas said. "We only use public algorithms because in long term they are more secure."
While the immediate threat to car owners is low, Biham says the research shows the technology used to protect remote keyless entry systems is outdated.
"There are other tools criminals can use today (to steal cars) that are easier," Biham says. "But we show that it's possible to (hack the locks) and these systems to be replaced."