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- HOOPSWORLD | Basketball News & NBA Rumors - http://www.hoopsworld.com -
Perkins: I Probably Made OKC Better
Posted By Susan Bible On March 27, 2011 @ 4:00 pm In All,NBA | No Comments
The Oklahoma City Thunder (47-24) currently sit atop the Northwest Division, fourth in the Western Conference. Obviously the team is squarely focused on preserving home-court advantage as the end of the regular season draws near. Last season the Thunder gave the Los Angeles Lakers a real scare in the first round of the playoffs; ultimately, OKC could not overcome the Lakers' distinct size disadvantage and lost the series (4-2).
This postseason, Oklahoma City is ready with new weapons in the front court.
It's been just over one month now since the Thunder acquired centers Kendrick Perkins and Nazr Mohammed. Since Perkins made his Thunder debut just six games ago the Thunder has gone 5-1, and that one loss (vs. Raptors, 95-93) could have, even should have, easily been a win.
With the two being crowned as the players who filled the Thunder's defensive shortcomings, we wondered if the pressure to succeed was mounting.
"Well, you know, I've been in every situation possible, so I don't feel any pressure," answered Perkins when HOOPSWORLD posed that question. "I've just got to go out there and do what I do, do what I can. As long as I be honest with myself, hold myself accountable, we're just gonna go from there.
"These guys are already good, so I just probably made them a little bit better," Perkins said with a sly smile.
The question begs: are Perkins and Mohammed the missing pieces that will propel the Thunder further in the playoffs this season?
"It's always a good thing to be wanted," began Mohammed. "Me and Perk, we're just trying to come here and give a little physical presence, show our leadership, go out there and show our experiences (with) both of us winning championships."
"I've always said that we were a good team, and now we feel that we are a better team that still has work to do," explained Thunder coach Scott Brooks. "We're still a team that's still developing. We have to get better. But Perk brings and Naz brings a lot of things that we need…that we can use…that we're excited to have."
Some of those things Brooks refers to are veteran leadership and, as Mohammed mentioned, NBA championship experience.
To interested observers the team appears excited by the roster additions, but some teammates are hesitant to pronounce Perkins and Mohammed as "the" answer in pushing them further in the playoffs.
"I just look at them as two great additions to this team," Eric Maynor said. "Guys that have been through it…knows what it takes…great teammates."
"I don't even go there," added Daequan Cook. "They come in and fill the places for this team. They're coming in doing a job that would we need to be done to help this team to win. I'm not gonna say they're the missing pieces. We're a good team. You add them to it, it makes a better team."
On the other hand, one Thunder teammate enthusiastically agreed the two big men, both 6'10", have filled the Thunder's holes on the defensive end.
"Two big enforcers," began Royal Ivey. "Perk a great defensive big, one of the best in the league. Nazr can step out and shoot the 17-footer. He's a good defensive big. You need some veteran guys who have both been there to the promised land and won. That helps the young guys out a lot. It's a good addition, both of them."
Ivey takes it even a step further when speaking about Perkins, who he calls a "defensive enforcer that brings a lot to the table."
"As he goes, we go," he said.
"We welcomed them in, and they bring it every day", shared Maynor. "The thing about them both, they just want to win. When you got guys that come in like that, it's good for the team."
{AUTHOR_BOX}One NBA head coach stops shorts of proclaiming Perkins a probable impact-player for the Thunder by the time the playoffs roll around.
"That remains to be seen," said Minnesota Timberwolves coach Kurt Rambis.
"He's always been a guy in Boston that they can allow him to play people one-on-one as opposed to not having to come down and help them," continued Rambis. "He's also done a real good job in learning their (the Thunder's) system…how to help and clog up the lane. He has the potential to be a good shot-blocker, charge-taker along with (Serge) Ibaka."
Rambis does admit Perkins "could be a key component for them" when the game slows down in the playoffs.
Brooks already sees Perkins' positive impact on his team.
"I think he's done a good job of really stepping up and figuring out how we do things," shared Brooks. "I think he's had an impact. I look at him like a Nick Collison. We don't look at his stats, (and say) 'OK, he had a great game tonight…he had eight points/eight rebounds.' No, we look at the little things that he does. He's a winner. He does a lot of things that helps you win, and a lot of those things, you don't see them on the stat sheet. But as you watch film – as you understand what he brings – he brings it every time down the court. He's very consistent in his effort, and all of his plays are all about winning."
In the past six games with Perkins on the floor the Thunder limited their opponents to an average 91.3 points per game. That's an amazing statistic given their season average is 101.0, not to mention the fact the league leader (Boston Celtics) boasts a slightly better 90.8 average points per game this season.
"Our defense has improved," Brooks said. "One of the things that we want to continue to get better all year long was defense, and we have done that. We were good in spurts throughout the year. I think we're starting the game off (with) better defensive focus."
With the Thunder, Perkins has averaged 23.8 minutes, logging 5.8 points, 7.2 rebounds, 0.8 blocks, .700 field-goal percentage, and even added 1.0 steals and 1.3 assists. His free-throw shooting of .438 leaves much to be desired.
"One thing about me, I'm not afraid to work on my flaws or anything to that nature," revealed Perkins when asked about his string of recent missed free throws. "I don't run from them. So I will get in the gym tomorrow shooting a lot of them."
Perkins has already shown vocal leadership on the floor. While Ibaka appears to be the one most benefiting from his on-court direction, Perkins hasn't held his tongue to any player.
"That's the kind of leadership you need," said Ivey. "Somebody who's gonna really lay the law and really hold everybody accountable. That's what he's good at, and he's been doing a pretty good job at it so far."
Mohammed, now in his 13th season, has shown solid play during his 13 games thus far: in 17.8 average minutes, he has posted 6.5 points and 4.5 rebounds. He's looking ahead toward the postseason.
"We're definitely starting to figure out one another, but we've still got a ways to go," explained Mohammed. "We're still trying to improve our defense. We're definitely trying to improve our half-court execution, because that's what playoff basketball is about."
While Mohammed talks playoffs, Brooks looks to the big payoff.
"I think every team wants to win a championship, and we are no different than all the other 29 teams," Brooks noted. "We're putting pieces together. Sam (Presti, the Thunder's executive vice-president and general manager) has done a good job of building this team."
In just a few short weeks, answers will be revealed as to how far the new-look defense will take the Thunder.
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The Irish government has donated $322,000 (€250,000) in emergency funding to Irish voluntary organizations on the east coast of the US in the wake of Hurricane Sandy.
After meeting with Secretary of State Hillary Clinton in Dublin last week, Deputy Prime Minister Eamon Gilmore announced the charitable donation.
Funding will be directed towards relief and reconstruction efforts in Breezy Point Queens, Staten Island and the Jersey Shore where Hurricane Sandy caused massive devastation to communities, including some with deep Irish roots.
The American Ireland Fund has also responded generously to the recent Hurricane Sandy disaster with a gift of $250,000 to assist relief efforts.
Read More: Hurricane Sandy one month on - Irish Day of Action reveals many still hurting in the Rockaways
Read More: Breezy Point -- Irish groups pledge massive support for homeless residents - VIDEO
The funds will be split among prominent Irish American community centers including; The New York Irish Centre in Long Island; The Emerald Isle Irish Centre, Queens; The Aisling Irish Centre; The Breezy Point Cooperative Disaster Relief Fund; The Parish of St. Francis De Sales; The FoodBank of Monmouth / Ocean County New Jersey and The Mayor's Fund.
In the wake of the Irish Government's donation, Congressional leaders will gather at Embassy of Ireland in DC to show their solidarity for for Sandy victims on Tuesday December 11.
Congressional Friends of Ireland Co-Chairs Rep. Peter King and Rep. Richard Neal of Massachusetts will be in attendance when Ambassador Michael Collins hosts a special event at the Embassy.
Donations will be accepted on the night for the AIF Washington DC Young Leaders Hurricane Sandy Relief 2012 Fund .
Hurricane Sandy one month on - IrishCentral ask New Yorkers if the US Government is doing enough:
Thanks....Just send the Check, no need to have 20 TD's coming over to present it.
These gombeen men are driving people into poverty in their own country while overpaying themselves with taxpayers money. In the latest budget they targeted the poorest to pay for the actions of reckless thieving bankers and the Catholic Church. Then over a few drinks melon head donates a quarter of million to a wealthy country on another continent just to satisfy his own vanity.
I think it's a good thing. You have to help your friends when they are cold and hungry, especially when politics maybe interfering with relief funds in the US.
To call this a "donation" is beyond the limits. This is organized theft by and for the Irish government. Your Irish g'ment is not solvent. What possible advantage would there be financially for Irish taxpayers to perform this deed without their permission? ... Other than to sink the Irish g'ment and taxpayers deeper into debt.

subset: commoncrawl


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New hack/slash game about a cheerleader zombie hunter
http://www.youtube.com/watch?v=fbMkVqzv ... ture=share
It looks like the best game ever made! I want it now... 2012 is so far away
Omg Using her boyfriend's decapitated head for special moves, yessss!!! I need this game.
I'll be in Turkey tomorrow, so I won't be able to play this until July first.. but I promise I'll finish it in 1 sitting when I'm back!jamesssxD wrote:3 days


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TITLE: Management of Chronic Rhinosinusistis
SOURCE: Grand Rounds Presentation, UTMB, Dept. of Otolaryngology
DATE: May 9, 2006
RESIDENT PHYSICIAN: Jean Paul Font, MD
FACULTY PHYSICIAN: Matthew Ryan, MD
SERIES EDITORS: Francis B. Quinn, Jr., MD and Matthew W. Ryan, MD
"This material was prepared by resident physicians
in partial fulfillment of educational requirements established for the
Postgraduate Training Program of the UTMB Department of Otolaryngology/Head and
Neck Surgery and was not intended for clinical use in its present form. It was
prepared for the purpose of stimulating group discussion in a conference
setting. No warranties, either express or implied, are made with respect to its
accuracy, completeness, or timeliness. The material does not necessarily
reflect the current or past opinions of members of the UTMB faculty and should
not be used for purposes of diagnosis or treatment without consulting
appropriate literature sources and informed professional opinion."
Sinusitis is one of the most common health care
challenges in the
The word Rhinosinusitis is replacing the term
sinusitis because sinusitis is often preceded by rhinitis and rarely occurs
without concurrent nasal airway inflammation. Rhinosinusitis has been defined
by the American Academy of Otolaryngology as an inflammation of the nose and
sinuses. It is believe that this
condition comprise a spectrum of inflammatory and infectious diseases.
The site of sinus and nasal obstruction is important.
The ostiomeatal complex is a region of key importance for the development of
rhinitis induce sinusitis. The area comprise the hiatus semilunaris, a
curvilinear groove between the uncinate process and the bulla, and through
which the frontal, anterior ethmoid and maxillary sinuses drain into the nasal
cavity. Inflammation or anatomic
obstruction by a mass on this area block drainage from these three sinuses leading
to stagnation of secretion and creation of a culture medium for infection to
Unfortunately, the accuracy of reported rhinosinusitis
cases is difficult to ascertain. The diagnosis on the basis of symptoms is
common but can be unreliable. This concern is especially true for the accurate
diagnosis of chronic rhinosinusitis (CRS). A rhinosinusitis task force in 1997
outlined "major" and "minor" criteria for diagnosing sinusitis. The
major criteria include facial pain, nasal obstruction, hyposmia, purulence on
examination, and fever. While, minor criteria include headache, fatigue, dental
pain, and cough. Studies have found the criteria to be sensitive but not specific.
Currently the gold standard for the diagnosis of chronic rhinusinusitis is
computed tomography.
The classification of Rhinosinusitis is based on
duration of sign and symptoms into acute, subacute and chronic. Acute is
defined as lasting up to four weeks, with total resolution of symptoms. The
term recurrent acute has also been adopted and is defined as four or more
episodes per year, with resolution of symptoms between attacks. Subacute is
persistence of sing and symptoms for more than four weeks, but less than twelve
weeks with total resolution of symptoms.
Finally, Chronic is 12 weeks or more of signs and symptoms.
Successful management of rhinosinusitis via medical or
surgical treatment is achieved in the majority of patients. In some cases symptoms
resolve spontaneously. Treatment of
chronic rhinosinusitis is intended to reduce symptoms and signs, improve
quality of life, and prevent disease progression or recurrence.
Medical treatment is the initial treatment choice
before opting for surgery in patients who do not improve. Many medical
treatments have been recommended or employed. Evidence for their efficacy is
rarely strong, partly because of the poor-quality trials in unselected groups
of patients2. Chronic rhinosinusitis involves multifactorial
etiology. The condition does not respond by simply making an empiric antibiotic
selection. There are several predisposing factors in chronic rhinosinusitis
which include host factors like allergic rhinitis, viral illness (children in
daycare), gastroesophageal reflux, anatomic obstruction, immunodeficiency, genetics,
congenital. There are also environmental factors such as irritants (cigarette
smoke), microbial (viral, fungal and bacterial) and even medication inducing
rhinitis medicamentosa. The quest and identification of factors predisposing to
chronic rhinosinusitis is key to guide appropriate management.
The most common indication for sinus surgery is
failing medical therapy of chronic sinusitis. Approximately 200,000 U.S. adults
undergo sinus surgery per year. Relative
indication include persisting obstruction to sinus aeration (e.g., polyp,
concha, septum), specific area of recurring disease and chronic or recurrent
acute rhinosinusitis who have not responded adequately to medical therapy.
Absolute indication include complications like brain abscess, meningitis,
subperiosteal abscess, sinus mucocele or pyocele, fungal sinusitis (all
varieties), massive polyposis (obstructing sinuses) and neoplasm or suspected
neoplasm (causing sinus obstruction).
Frequently a
combination of measures is employed in an individual patient. Some management
are directed at improving sinus ventilation and drainage like oral hydration,
saline irrigation, mucolytics and decongestants. There are other designed to
reduce inflammation corticosteroids, antihistamines, macrolides and anti-leukotriens.
Finally, there are those designed to treat infection such as anti-biotics and
antifungals, treat an anatomic abnormality and those directed at avoidance of
allergens. The key to breaking a cycle
of recurrent or chronic sinusitis is the aggressive combination of antibiotics
with therapies directed at predisposing conditions for a length of time
adequate to allow for healing of upper respiratory tract mucosa with recovery
of local immune defense14.
Allergens and Irritants
Up to 30% of the adult population is allergic by skin
testing to at least one common aeroallergen, and the percentage is probably
much greater among patients presenting with a history of chronic sinusitis. Allergic
rhinitis is probably the second most common predisposing condition to chronic
sinusitis in children (after viral upper respiratory infection) and perhaps the
most common predisposing factor in adults14.
A combination of allergic history and positive skin prick testing is key
in the management of chronic sinusitis in a patient with allergic rhinitis. This
condition causes mucosal inflammation and hypertrophy predisposing to blockage
of the ostiomeatal complex. This is the reasoning behind innovating research
directed at treating the antiinflammatory response as a route of medical
management in chronic rhinosinusitis.
Sign and symptoms of chronic rhinosinusitis occur in response to irritant exposure. There is increasing evidence to support the theory that exposure to air pollution can impair mucociliary protection and potentiate sensitivities to common aeroallergens by stagnation of this agents. Avoidance and protection against smoke, pollution, and occupational irritants usually is advised to counteract these predisposing factors.
Saline Irrigation
Use of intranasal saline has been shown to decrease
nasal symptoms and improve quality of life in allergic rhinitis and chronic
rhinosinusitis. Saline spray increases mucociliary flow rates counter acting
the effects of irritants and other numerous factors that affect mucociliary
clearance. It also has a brief
vasoconstrictive effect that leads to some short term symptomatic relief. Also,
nasal saline irrigation mechanically rinse away predisposing agents such as
aeroallergens like pollen, mold, dust,
and particulate of air pollution. Although it has some symptomatic relief, patients
with chronic rhinosinusitis are told to use saline at least twice daily as a
preventative measure rather than starting when clinical symptoms manifest.
An acidic milieu is thought to cause the "gel" state (more viscous) of mucus to predominate, where as an alkaline milieu is thought to cause the "sol" state to predominate. This is the rationale for adding baking soda to saline irrigation solutions.
Guaifenesin is the most commonly used mucolytic agent. High doses of this medication are required to obtain an effect on mucous. At these amounts, patients often experience emesis and abdominal pain. Wawrose in 1992 showed significant improvement of nasal congestion and symptomatic relief in patients with AIDS and low CD4 counts.
It is sometimes contradictory to use an anti-inflammatory
agent that can lead to immunosuppression like corticosteroids in the treatment
of sinusitis which is consider having a significant association with microbial
infection. Nonetheless, a short course of steroids can induce a significant
anti-inflammatory and beneficial effect in the management of severe nasal
mucosal congestion in allergic rhinitis patients. This brief period induce
symptomatic relief and reduction of nasal and sinus mucosal inflammation
promoting a better scenario for the management with topical agents, improving
compliance and rate of benefit.
Corticosteroids have multiple immunomodulator mechanisms including
stabilization of mast cells against mediator release, block formation of
inflammatory mediators, and inhibit chemotaxis of inflammatory cells. It is
important to keep in mind the adverse effect of systemic steroid use and the
contraindications that include diabetes, peptic ulcer disease, glaucoma, severe
hypertension, and advanced osteoporosis. Even a short course of steroids can
significantly increase the blood pressure and glucose levels in patients with
predisposition to hypertension and diabetes.
Close monitoring and immediate withdrawal for side effects is warranted.
Topical nasal corticosteroids are a very effective form of treatment for allergic rhinitis and chronic rhinosinusitis. Their anti-inflammatory effect is localized and their systemic absorption has been shown to be negligible. The local reduction of inflammation prevents blockage and improve patency of the ostiomeatal complex. After use by at least 7 days, nasal corticosteroids have been shown to inhibit both immediate and late-phase reactions to antigenic stimulation in patients with allergic rhinitis14. An estimated 90% of patients with allergic rhinitis will experience improvement in nasal allergy symptoms including chronic nasal congestion with topical nasal steroid preparations accounting for a marked increase in popularity of these medications over the last decade14.
Some common adverse effects of topical nasal steroid use include nasal irritation, mucosal bleeding, and crusting. Septal perforation is a rare complication and the risk can be increased for patients living in very dry climates. The ingredient propylene glycol contained in the preparations is responsible for this complains. This can be alleviated by switching to an aqueous delivery system. The addition of nasal saline wash in conjunction with topical steroids can lessen or eliminate these common adverse effects.
Decongestants are α-adrenergic agonists that
induce a sympathetic response leading to vasoconstriction of dilated mucosal
blood vessels. Decongestants are best used for short (3–5 days) courses at the
beginning of treatment for sinusitis or allergic rhinitis.
The most common oral decongestants are pseudoephedrine and phenylpropanolamine. This systemic agents achieve symptomatic relief, but lead to several adverse effects that are related to its sympathetic stimulation including insomnia, heart palpitations, and elevated blood pressure. Oral decongestants are indicated principally for symptomatic relief of nasal congestion and have not been shown to have therapeutic efficacy for the treatment of sinusitis14.
Topical agents include phenylephrine and oxymetazoline. This agents lead to a local excitation of alpha adrenergic receptors leading to a localize vasoconstriction and decrease of mucosal edema. All topical agents exhibit rebound vasodilation, which can be demonstrated by rhinometric analysis of nasal resistance as early as 3 days after beginning therapy. Clinical rebound congestion or rhinitis medicamentosa usually requires at least 10 days to 2 weeks of topical decongestant use to become apparent. This is the reasoning of using decongestants for short (3–5 days) courses at the beginning of treatment for sinusitis or allergic rhinitis.
The use of antibiotics in chronic sinusitis is a topic of high controversy. It's efficacy, duration of therapy and agents to be use have been extensively debated. Some consensus is apparent on the idea that antibiotic therapy for chronic sinusitis should be based on culture results. This is based on the increase in antibiotic resistance that have been increasing consistently throughout the decades.
The culture can be obtained by direct visualization under endoscopy of purulent secretions from the middle meatus. Although the maxillary tap is the gold standard for culture diagnosis, this method is highly uncomfortable to the awake patient. Although there is not a definite large randomize control trial comparing both techniques, the endoscopic technique correlates well with the maxillary tap and is less traumatic to the alert patient. Nevertheless, the maxillary taps still a very effective tool especially on the ICU setting.
The first-line antibiotics for chronic rhinosinusitis include amoxicillin-clavulanate and second-or third-generation cephalosporins. The respiratory quinolones are helpful second line agents for refractory cases to firs line antibiotics.
Bacterias have developed multiple mechanisms of
resistance. Alteration of the penicillin binding proteins is the most common
reason for penicillin resistance in Streptococcus pneumoniae infections. This
mechanism of resistance is overcome by increasing the penicillin component to a
much higher dose. This is the rational behind dosing children with 60 to 90
mg/kg per day instead of 40 mg/kg for amoxicillin. Haemophilus influenzae also
utilize this type of resistance, but to a lesser degree.
According to the American Academy of Otolaryngology approximately 40% of Haemophilus. influenzae and greater than 90% of Moraxella catarrhalis produce beta-lactamase. This enzyme breaks down the b-lactam antibiotics. β-Lactamase-mediated resistance to the early second-generation cephalosporins is high among strains of Haemophilus influenzae and Moraxella catarrhalis. Stabilization of penicillin by adding clavulanate overcomes this enzymatic action.
Newer generation macrolides such as clarithromycin and
azithromycin achieve excellent mucosal levels but should be considered backup
drugs. Azithromycin appears to be more potent against Haemophilus Influenzae,
whereas clarithromycin may be slightly better against intermediate resistant Streptococus
Bacteria's have also developed resistance against macrolide and even fluroquinolones. Streptococus pneumoniae have been shown to develop two different mechanism of resistance against these two antibiotic families. One of the resistant apparatus is the efflux pump which eliminates the antibiotic from the microorganism interior before it can exert its effect. The other mechanism of resistance is the development of altered target proteins which prevent the connection of the antibiotics to the cell wall or mitochondria stopping its action inside the bacteria.
Authors have noted a doubling of pneumococcal
resistance to macrolides over the past 10 years from approximately 10% to 20%
leading to recommendations that these drugs (and fluoroquinolones in adults)
not be used as first-line therapy for sinusitis14. Clindamycin is
another alternative which should be reserved for culture-documented resistant Streptococus
Most authors recommend treating chronic sinusitis with
a broad-spectrum antibiotic for up to 3 weeks. After 3 to 5 days of treatment
there should be symptomatic improvement. After 10 to 15 days of treatment, symptoms
should resolve. The logic of continuing therapy for another week is to allow
for further diminution of mucosal edema and mucociliary function thus gaining
resistance against new infection.
Many clinicians will follow the
3-week treatment course of antibiotics with a 3- to 6-week course of once-daily
prophylactic antibiotic therapy for patients with a history of rapid recurrence
after previous treatment. The goal is to get the patients through their window
of vulnerability to new infection while mucosal recovery.
Prolonged use of low-dose macrolides in patients with chronic rhinosinusitis was found to be effective even when the identified bacterial pathogen was not sensitive to this agent. This management has also been found to decrease the size of nasal polyps.
Antiinflamatory effect of Macrolide
The observation that macrolide antibiotics were steroid-sparing in patients who had steroid-dependent asthma has been present for decades. This was thought to be due to inhibition of steroid metabolism. The concept of using long-term, low-dose macrolides for treatment of Chronic rhinosinusitis evolved further, primarily in Japan4.
An interesting aspect of the pharmacokinetics of
macrolide antibiotics is their extensive tissue uptake and intracellular
accumulation. Macrolides accumulate in inflammatory cells at concentrations up
to several hundred-fold higher than concentrations in extracellular fluid. The
macrolide antibiotics decrease cytokine production (IL-5, IL-8, GM-CSF,
TGF-β, IL-6, IL-8, TNF-ɑ),
altered structure and function of biofilm, reduced expression of cell surface
leukocyte adhesion molecules, accelerate neutrophil apoptosis, impaired
neutrophil oxidative burst, decrease secretion and improve mucociliary
clearance, and Inhibited release of elastase, protease, phospholipase C, and
eotaxin A by P aeruginosa4.
Meta-analysis of anti-inflammatory effect of macrolides in
Chronic rhinosinusitis
Type of study |
Dosage 24h (mg) |
(months) |
Macrolide |
Results |
Reference |
Prospective, randomized, controlled trial, n = 90 |
1000 (2 wk) |
3 |
Clarithromycin |
As effective as surgery in chronic sinusitis |
Ragab, 2004 |
Prospective, open, n = 17 |
500 |
12 |
Erythromycin |
12 responders, mucocillary transport, headache, postnasal drip, all
improved, P<.05 |
Cervin, 2002 |
Prospective, open, n = 20 |
1000 |
0.5 |
Clarithromycin |
Improvement in CD68, IL-6, IL-8, TNF-ɑ and
clinical parameters |
Macleod, 2001 |
Prospective, open, n = 20 |
400 |
3 |
Clarithromycin |
Reduction of IL-8 in nasal lavage, decreased nasal polyp size |
Yamada, 2000 |
Cervin et al. 2005
The above table shows several of the prospective studies done in the use of macrolides in long term management of chronic rhinosinusitis (CRS). Clarithromycin is the macrolide most studied in CRS. While Azithromycin lack studies in CRS. The table shows the marked success of this management in the symptomatology, reduction of cytokines in the tissue, decrease in nasal polyp size and effectiveness in comparison to surgery. The long term use in the above table varies, but an average of 3-12 month is seen.
Gastroesophageal Reflux (GERD)
There is a new trend of research in the involvement of GERD in upper airway pathologies. Reflux is said to be associated to chronic rhinosinusitis. The mechanism is not cleared and studies are necessary to further enlighten this discussion. However, it is thought that the reflux of acid content reach the nasopharynx and nasal cavities leading to chronic mucosal irritation and sinusitis.
Adult patients with chronic sinusitis and a history of
heartburn could benefit from antireflux regimen including precautions and medication.
In young children the relation is more evident presumably due to the closer
proximity between the esophageal inlet and larynx to the soft palate and
nasopharynx. Suspicion should rise in children with chronic congestion, rhinorrhea,
excessive spitting up in infancy, low weight percentile, failure to thrive, chronic
stridor and reactive airway disease.
Viral infections
Viral infections are the most common predisposing factors for sinusitis in children. Day care is an important risk factor for the development of viral infections due to the proximity and relation characteristics of children in this environment. The current management for viral infections is prevention by frequent hand washing and decrease exposure. Children with chronic rhinosinusitis may benefit from changing to a day care with fewer numbers of children to reduce viral exposure. Also an alternative are vacation periods from the daycare to allow for resolution of symptoms and decrease mucosal inflammation and improve mucocialliary clearance as a measure for improving natural resistance to the condition.
Interferon alpha-2 (IFN α2) can potentially block
the penetration of viruses through respiratory mucosa. Intranasal IFN α2,
when used as a once-a-day nasal aerosol, has been shown to potentially prevent
colds in people exposed to family members with upper respiratory infections. Although
medications like Interferon alpha2 has shown some improvement its usage is
limited by its cost.


text:
The Unbearable Lightness of Vitriol
http://www.mlgoodell.webs.com Ever since President Barack H. Obama (D-Chi) traveled to Tucson, AZ to heal a troubled land, pundits have studied the Republican Party, wondering when that seething morass of hatred and invective will erupt again in partisan vitriol. Early indications are not promising. It is a pity that conservatives are so consumed with hatred and racist rage that Obama's words of truth, beauty and wisdom | Read More »


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The Loyola Maroon VOL. XXXIII Loyola University, New Orleans, La., Friday, May 4, 1956 NO. 23 Council President TOMMY DUBOS DuBos To Head SC Tommy Dußos, law school president, was elected president of the 1956-57 Student Council Tuesday at a meeting in the Student Lounge. Other officers are: vice-president. Matt Schott, A&S president, secretary, Lydia Larose, A&S junior representative; treasurer. Bob Daigle, business administration president; and parliamentarian, Ed Pesce, A&S junior representative. The new officers were sworn in at the meeting by outgoing Student Council president, Tommy Walshe. In the runoff for the presidential election, Schott was nominated for the top office but declined, leaving Dußos as the only candidate.For the office of vice-presidency, Schott was the only one nominated. Larose defeated Olga Seiferth, college of music representative, in the final tally. Daigle was the sole candidate for the office of treasurer. The race for parliamentarian ended in Dan Stapp, law school representative, losing out to Pesce. NEWELL STEWART Newell Stewart To Address APhA Newell Stewart, executive vice-president of the National Pharmaceutical Council and former mayor of Phoenix, Ariz., will be the principal speaker at the student affiliate of the American Pharmaceutical Association banquet tomorrow at 7 p.m. in the St. Charles Hotel. Past president of the American Pharmaceutical Association, Stewart has also served as president of the National Association of Boards of Pharmacy. Given annually by the college of pharmacy, the banquet is held in order to honor one of the outstanding pharmacists in the state as well as a Loyola student who will receive the student activity award. Stewart, a native of Sisterville, W. Va., received hi* pharmacy degree at the West Virginia State University at Morgantown. He moved to Arizona where he established his own pharmacy in 1927. Prominent in national pharmaceutical organizations since that time, he has served as president of the Maricopa County Pharmaceutical Association and, from 1936 to 1953, as a member of the Arizona Board of Pharmacy. A former lecturer in pharmaceutical jurisprudence at Arizona's College of Pharmacy, he has also served as chairman of both his district of the national Association of Boards of Pharmacy in 1940 and of the house of delegates of the American Pharmaceutical Association in 1950. Other speakers at the banquet are the Very Rev. W. Patrick Donnelly, S.J., University president; Dean John F. McCloskey of the college of pharmacy, and Dr. Edward J. Ireland, professor of pharmacology and pharmacognosy.Alpha Sigma Nu Honor Group Formally Initiates 15 Students Tapping Held At Ceremonies Monday Night Fifteen outstanding students were formally initiated into Alpha Sigma Nu, national Jesuit scholastic honor society, Monday in the President's office, the Rev. Charles C. Chapman, S.J., moderator, announced. They are, from the college of arts and sciences, Carl Henry Brans, junior; Charles Suhor, senior; Lynn Daniel Ketchum, junior; George A. Frilot, 111, senior; and Kenneth Urquhart, senior. From the college of business administration: juniors Harold Kerner and Edmund Schmidt. From the college of pharmacy: Henry Maggio and John Montelepre, Jr., juniors. From the school of dentistry: Jim« D. Atkinson and John D. Shea, juniors. From the school of law: Nicholas J. Gagliano, and Albert James lluddlest*)n, juniors. From evening division: Philip Andrew Forschler, Jr., and Prentiss Earl Cobb. In honor of its 20th anniversary, charter members from 1936 were guests at the induction ceremonies and the buffet supper which followed, Father Chapman said. To be elected to Alpha Sigma Nu, a student must be at least a junior, have a high B or A average, and be recommended by the dean of his school. Membership iB limited to two members from each school. Suhor Urquhart Bran* Frilot Shea Huddleston Montelepre Cagliano Schmidt Maggio Ketchum Forschler Kerner Atkinson Cobb Legal Frat Picks Leadets Herbert W. Christenberry, Jr., law junior, has been installed as dean of the Farrar Senate, Loyola's chapter of Delta Theta Phi, national legal fraternity. Other officers installed include law juniors: John Peytavin, vice dean; Tom Toranto, clerk of roles; Friti Westenberger, clerk of the exchequer; Frank Demarest, master of the ritual; Bob Treuting, bailiff; Ronald Levy, tribune; and Dan Stapp, parliamentarian. Thirteen pledges to the legal frat were initiated Monday at "Little Woods." The new members include: Dennis Rousseau, law junior, and law freshmen: Charles Anderson, Matthew Belin, James Bowea, Robert Tracy, Orr Adams, Thomas Woods, George Frilot, Charles Gaudin, William Landry, James Schwing, Thomas Walshe, and Henry Mason. Thespians Elect Hoag President George Hoag, arts and sciences junior, was re-elected president of the Loyola Thespians Wednesday night at a meeting in Marquette Auditorium. Also elected were Bill Longfellow, vice-president; Kate Scully, secretary for a second term; Bill Wells, treasurer; Gloria de Bram, librarian-historian; and James Arceneaux, parliamentarian. MASS Students are inTited to attend a Dialogue Max Monday, Wednesday and Friday at 7 a.m. in the Thomas Hall Chapel, according to the Rev. Harold L. Cooper, S.J., University chaplain.He said that Mass booklets will be placed in the chapel. Tri Beta Sets Lecture Today, Initiation Sun. Tri Beta, national honorary biological society, will sponsor a lecture by Dr. Emily J. Bell, assistant professor of biochemistry at Vanderbilt University, today at noon in Bobet 304, accord to Lynn Ketchum, president.Her topic will be "The Metabolic Cycles of Bacteria." The society will conduct informal and formal initiation of the provisional and active members Sunday at 7 p.m. in Bobet 304. Provisional members are freshmen who have completed one semester of biology work and who have maintained a B average in biology. They will become active members next year. Active members are those who have completed two years of biology work and who have maintained a B average in biology. Those to be inducted include: Active members: Salvador Al phonse, Jack Andonie, Mary Arnold, Noemi Breland, Joan Briglien, Nancy Carlos, Susanna Coco, Anna Culver, Barbara Flink, Pamela Jones, Bernard Keller, Valerie LaCour, Salvador Laßocca, Loretta Logan, Charles Mary, Michel Msdawar, Robert Miller, William Oberbelman, Irvin Plaisance, Clements Rieffel, Virginia Rowell, Marlene Ruckert, Judith Sanguily, Daria Syrotiuk, and Mary Wetsel. 'Provisional members: Dig by Barrios, Joan Crain, Mary Christina, William Curry, Jr., Jeanne Delaup, Jean Dufau, Jacquelyn Ford, Rene Fourcade, IN, Norman Maestri, Louis Maumus, Robert Mellican, Claude Pumilia, William Roper, Shirley Talamo, Richard Vidacovich, George Watkins, Delosa Young, and Franklin Troncale.Following the informal and formal initiation, there will be a movie and refreshments. Graduates To Hear Monsignor DeBlanc The director of the National Catholic Welfare Conference's family life bureau will be principal speaker at commencement exercises May 30 in the Fieldhouse, the Very Rev. W. Patrick Donnelly, S. J., Loyola president, announced. The Rt. Rev. Msgr. Irving A. Deßlanc, who authors a nationally syndicated column, "Making Marriage Click," besides directing the Washington, D.C., bureau, is a native of New Iberia, La. He has given more than 200 marriage conference!, family retreats, and missions Formerly chaplain to the Catholic Student Center at Southwestern Louisiana Institute in Lafayette, he taught sociology, liturgy, and applied philosophy before taking over his national position. He was active in youth work in the Diocese of Lafayette, serving as dioceson director of sodalities and Junior Newman clubs for 15 years. He represented the Most Rev. Jules B. Jeanmard, Bishop of Lafayette, in state legislature discussions on socio-economic issues, and frequently was called upon to arbitrate labormanagement disputes. The 42-year-old prelate is a former state chaplain of the Knights of Columbus and vicepresident of the Louisiana state advisory board of institutions. He attended Notre Dame seminary here and is a former president of its alumni organization. He studied special courses at Loyola, Louisiana State University, Catholic University of Washington, D.C., and the University of Louvain in Belgium. SC To Present Award Day The initial Student Council Award Day will be Wednesday at noon in the quadrangle, Tommy Walshe, out-going president, announced. Not to be confused with the annual faculty Award Night, the program will consist of the presentation of 35 Council citations, awarded on the basis of one year's outstanding extracurricular activity. Chosen by the Student Council at three successive closed meetings, the students receiving the honor for the first time will be presented with leather-bound cert i f icates of achievement. Those who have been previously awarded citations, will receive Student Council award keys. The exercise will open with selections by the University orchestra under the direction of George Jansen. Maroon All-American liyola Maroon hangs up its seventh consecutive AU-American placard this week after receiving emester rating from the Associated Collegiate nday. ;ing, made on the basis of a critical survey each puts the campus weekly in the organization's racket with eight other papers in the 2001-4000 it class. ■ e papers are entered is of weeklies. 23 individual claiiei neral classes on which ebert, columnist and ty editor of the St. eer Press and Dis- Iged the Loyola pub-20 per cent ranked the highest given), 70 excellent, and 10 per good. pus publication ranked I top three ratings in s category, erior categories, with amments, were: ources—"l think that if anything stands out of your paper this semester, it is the graphic human picture of campus life portrayed in the pages!" Speech and interview—"The story: 'Ex-Colonel Seeks Degree at 41,' was a professional piece of writing! Also, I like the treatment of such stories as 'Research on Shrimp'." Editorial page features—" Society Notes' is one of the better columns of its type . . . 'Halls of Ivy' also has good flavor, some fine writing on interesting subjects."Editorial page make-up—"Your editorial page looks as interesting as the content." Photography—"Some outstanding photography." The Maroon ranked excellent in balance between new* sources; treatment of copy; creativeness; style; lead*; editorial!; iports coverage; sports writing ("I seldom rank this section 'excellent.' I like the style."); front page; masthead; sports display; inside news pages; typography; and printing.Copyreading was the sole category in which the Loyola paper ranked as low as "very good." Below this rank, papers can be judged poor, weak, fair, or good. The same staff which now appears on The Maroon masthead handled production of the fall issues with the exception of several reporters who resigned during the year. Loyola Nite Pops Concert Sunday, 13th "A Nite at Loyola," a pops concert featuring the best in student vocalists and instrumentalists on the campus, will be presented Sunday, May 13 at 8 p.m. in the Loyola quadrangle. Music for the event, sponsored by Phi Mu Alpha Sinfonia, national professional music fraternity, will be by the Loyola Concert Band under the direction of George A. Jansen, and Campus Capers orchestra, under the baton of Louis Pendarvis, according to Pat Harrigan, Sinfonia president. Soloists to appear will be Ralph Slifkin, baritone, Southern Regional winenr of 1956 auditions of the Experimental Opera Theater of America; and Barbara Faulkner, soprano, winner of Blue Key Talent Night. Other soloists are John Paquette, tenor, and Wanda Laris, pianist, also Talent Night winners, and Pendarvis, trombonist. Arthur Cosenza, director of the Loyola Opera Workshop, known for his appearances with the New Orleans Opera, will be master of ceremonies. Tables will be set up in the quadrangle "pops style, under the stars," Harrigan said.
Object Description
Title | Maroon |
Masthead | The Maroon Vol. 33 No. 23 |
Publisher | Loyola University (New Orleans, La.) |
Coverage | United States; Louisiana; New Orleans; |
Date | 1956-05-04 |
Type | Text |
Source | Loyola University New Orleans Special Collections & Archives (http://library.loyno.edu/research/speccoll/) New Orleans, LA |
Format | TIFF |
Subject | Loyola University (New Orleans, La.) |
Rights | Digital rights are held by Loyola University New Orleans. Copyright is retained in accordance with U.S. copyright law. |
Creator | Loyola University (New Orleans, La.) |
Relation-Is Part Of | http://www.louisianadigitallibrary.org/cdm/search/collection/LOYOLA_UMN |
Language | en |
Digitized By | BSLW |
Digitized Date | 2012-2013 |
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Image courtesy of FlashGlamTrash
In an interview with The Guardian, British Vogue's Alexandra Shulman reveals the secrets behind choosing a cover girl, although she admits that there is no set science behind the agonising decision. "It's difficult to say what will sell" Shulman explains, "Kate Moss sells well for us but then we tend to play to our strengths and put her on the September cover - it's better to use your ammunition on a big issue rather than battling against a difficult seasonal sensation".
Despite describing Moss as a safety cover girl, Shulman remembers the 2003 Vogue cover with the waif-like rock chick styled as David Bowie's iconic Aladdin Sane sleeve as a "complete catastrophe". Other things to avoid include dirty colours such as mustard or aubergine, and high fashion pieces - "a real thumbs down". "The evidence suggests that black cover girls don't sell as well as white cover girls," she admits with regret, although Glamour's Jo Elvin disagrees with such narrow conventions.


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Sunday Real Estate Round-Up, 02/27/11
Filed under: Estates, Celebrity Shopping
From the Wall Street Journal's Private Properties:
--Jigsaw Ranch, a 90-acre Aspen, Colorado estate owned by George I. Rosenthal and Mark A. Rosenthal, the father and son behind Rosenthal Estate Wines and other businesses, has listed for $48.5 million.
--A waterfront Kauai estate that has been in the same family since 1915 has hit the market for $24.5 million. The Faye House, shown above, is listed with Neal Norman of Koa Properties Land & Homes.
--Venture capitalist Fred Adler and his wife, Catherine, are asking $24 million for their ocean-to-intracoastal home in Palm Beach. The listing is here.
From the NY Post:
--New Knicks star Carmelo Anthony is searching for a downtown rental in the $30,000-a-month range. Potential new homes include 158 Mercer St., the same building where Jon Bon Jovi lives and SoHo Mews at 311 West Broadway where Justin Timberlake has a place. Fellow Knick Amar'e Stoudemire is renting a West Village condo for $37,500 a month.
--Princess Khaliya Aga Khan, the wife of Prince Hussain Aga Khan and daughter-in-law of Shia Ismaili Muslim leader Aga Khan IV, just rented an apartment in the Richard Meier-designed condo building at 165 Charles St. for $19,500 a month.
--Actor Dean Winters, best known for HBO's "Oz," recently checked out a $25,000-a-month rental a couple floors up from the princess.
--A mystery Russian buyer has signed a contract to buy Al and Patsy Kahn's five-bedroom, 62nd-floor apartment at the Time Warner Center for about $20 million. It was originally listed for $33.6 million last year. Last year the couple, which is splitting up, bought Bernie Madoff's penthouse at 133 E. 64th St. for $8 million.
--Former Yankee pitcher and five-time World Series winner David Cone is buying a condo in the $4 million range at the Lucida. The shiny eco-friendly building at 151 E. 85th St. includes a La Palestra fitness center.
--DailyCandy founder Dany Levy is renting a three-bedroom unit at 33 Fifth Ave. in the $13,000-a-month range.
From Greenwich Mean Time:
--Rumor has it that Billy Joel was the purchaser of Leona Helmsley's estate, Dunnellen Hall in Greenwich. We heard it sold last fall for $35 million after being on the market for as much as $125 million.


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Hello I am fairly new to transcribing records and was wondering if anyone can tell me where it is that the following people moved to from the Household Examination:
Pehr Johansson moved to a place I do not understand in 184? something
Johanna Johansdotter moved to a place I do not understand in 1840.
These are both from a Dala Household Examination 1833-1846. I just need help with where they went anyone that can help is appreciated.
Pehr moved to Segerstad and Johanna to Alingsås. There is a place called Segerstad outside Mariestad (where I live) and Alingsås is a town a bit north of Gothenburg.
© 2013 Created by Nat Ins for Genealogical Studies.


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The Bureau of Land Management's revised notice for the North Fork minerals lease sale has addressed the issues raised by the county government in the original sale notice.
The Board of County Commissioners heard a report on the revised notice from local government designee Bruce Bertram at its Nov. 19 meeting.
Read more...
The state's road builders at CDOT are dealing with the same problems of keeping the rural traffic ways in good condition as local municipal and county governments are.
"Rural roads are about 50 percent in poor condition," CDOT's Region 3 Transportation Director Dave Eller told the Board of County Commissioners on Nov. 19.
Page 331 of 561
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If you want to support your community newspaper, but do not want to receive a printed newspaper, please consider making a donation . . .


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by Jaime Laubhan-Oliver
Published 12.12.2012
From D Weddings Spring-Summer 2013
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Please use this form to describe the issue in as much detail as possible so we know how to reproduce it.


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My daughter and I stayed one night at Little York B&B. Charming old farmhouse in small town just minutes from Charlottetown. Robert, our host, prepared a lovely breakfast. The room and bath were nicely decorated but temps.in Sept. were cool and we didn't feel comfortable using space heater during the night. Location was good and views of the countryside were... More
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Friday, 25/05/2012
Kick off 19:30 BST at Deepdale, Preston
UEFA U19 Championship, Elite Qualifying Round
England - Chalobah 48' Thorpe 53' William Keane 83',90' Todd Kane 88'
Brought to you by The FA
90'William Keane. The Manchester United man gets his second of the night.
89'Off, Harry Kane. On, Benik Afobe. England's final switch sees Benik Afobe come on for the last few minutes.
88'Todd Kane. It's 4-0, as Chalobah's pass picks out Chelsea team-mate Todd Kane and he drills home.
83'William Keane. Will Keane gets England's third goal, finishing well with a low, left-footed shot in the area.
80'Off, Ross Barkley. On, George Thorne.
79'Todd Kane, playing in a right wing position, races onto Michael Keane's raking pace and his low cross almost picks out Will Keane.
77'Off, Rok Baskera. On, Jan Dornik.
74'Marko Kovjenic shoots wildly off target from 30-yards.
73'Harry Kane stings the hands of Barukcic with a low shot, after cutting in from the left. The Spurs man has done everything but score tonight.
71'Off, Saido Berahino. On, Todd Kane. England make their first substitution of the evening.
67'Johnstone forced into a great tip over the bar to turn Luka Kranjc's deflected shot behind for a corner.
53'Tom Thorpe. It's 2-0 now. Tom Thorpe latches onto Ross Barkley's through ball and scrambles home after rounding the 'keeper.
48'Nathaniel Chalobah. England take the lead, through Nathaniel Chalobah, who casually curls home into the top corner from 25 yards.
46'Tom Thorpe sees a header cleared off the line from Lundstram's corner.
45'England get the second-half started.
44'Jack Robinson. The left-back is booked on the stroke of half-time for a foul 40 yards from goal.
44'Baskera fires the resulting free-kick wide of the target from long range.
37'Nathaniel Chalobah. The England midfielder is cautioned for a foul on Praprotnik.
33'Erik Janza. The defender is booked for hauling down Eric Dier in a promising position on the right.
30'Johnstone makes a straight-forward save from Prapotnik's shot.
29'John Lundstram's free-kick into the box threatens, but no-one gets that crucial touch and it carries through to Barukcic.
27'Nejc Praprotnik. Another nasty foul on Harry Kane, another booking for the Slovenians.
22'Ross Barkley's pacy cross from the right almost catches out Slovenia 'keeper Mateo Barukcic.
16'A neat move involving Saido Berahino and Kane ends with the latter's cross being cleared just ahead of Will Keane.
10'England enjoyed the best of the possession so far here, but no break through at either end.
09'Harry Kane tries his luck with a long range shot, but drags it just wide.
05'Sam Johnstone saves with his foot to cut out Rok Baskera's low shot after Michael Keane's slip allowed the winger to break clear.
03'Marko Rojc. The Slovenia midfielder is cautioned for a late challenge on Harry Kane.
00'The teams have been named and you can see who lines-up by clicking on the 'Team Sheet' icon at the top of the page.
KOThe game is underway, at a sun-stroked Deepdale.


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You're watching...
Gov. Fortuno on Revamping Puerto Rico
Puerto Rico Governor Luis Fortuno discusses how the territory revived its economy.
May 11, 2012
You're watching...
Puerto Rico Governor Luis Fortuno discusses how the territory revived its economy.
May 11, 2012
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America's on the road to serfdom mainly because our politicians won't stop spending.
Few years back one part of America was even further down that row.
-- -- -- Politicians are spent so much intact so much the business fled.
They're deficit was -- -- when the current governor was elected he found there wasn't even enough money to pay the government's workers.
That governor is Luis for to a -- he change things and may have taken Puerto Rico off the road to search them so what did you do.
Well we we actually did what every American family doesn't -- what every basis then -- -- dust and their basis.
Actually we'd stop spending more than we were taken in.
And -- and we just focus on what was important.
And -- we started lowering taxes.
But you can't.
Cut the deficit just by lowering taxes unless -- cut spending big in in the mainland.
Have not wanted to do -- three years time we have caught our state budget deficit by 90%.
And we are in our wrote to balance our budget next year are how you you fired workers even.
In Wisconsin with all that -- the governor didn't fire anybody -- you actually fired government workers.
But the other day I commenced -- final salary so I cut my -- -- by 10%.
I froze everyone salaries I actually cut dramatically in all of forward contracts.
Leases merge agencies but on the other day we have no choice so we have to let go people.
And then we also provide a mechanism for others to leave and actually -- their own businesses and the other day they're making a lot more money.
And I -- makes more sense for -- for taxpayers here we interviewed one woman who was upset she was laid off but then she started her own business.
Which he even named after the law that's fired her last seven -- -- see actually it was the most difficult to Vissicchio I'm ever made in public life.
Having said that however it was the right thing to do.
And that meant 39000.
Fewer people now work for the government in three years 121500.
Were fired something you -- hear much about in the United States this wasn't.
Popular you were really and popular at first people.
Practically rioted outside your house and I and it's understandable again it it is a very tough position.
And where you are used to having the -- take care of everything.
You wonder what's gonna happen the next day -- the next day -- we set up you know the proper conditions you set of your own business.
Now or you go on work with somebody else's basis and proper conditions that included simpler rules actually.
-- -- processes would is that it -- -- real so crazy that it -- start in business accepted to start a business so we've simplified it dramatically.
We have you want to talk 28 permits to open a store value at a one office sector you can do it on -- now.
And -- one result of this is the businesses that had fled are now returning of course they're expanding.
A lot of people are looking at us I -- and Wal-Mart Costco Coca-Cola.
Drug companies exactly.
It just makes sense to actually to -- basis where -- you're want to.
And and where it simpler to set up -- this -- how we what we can keep more of year old Carter money.
Puerto Rico is the good news story it it in mind depressing book about deficit spending I have this vision that Americans are gonna.
Go to their state capitals with a sign -- and start saying the politicians know you can't spend all our money you don't make it better.
I mean you have any sense that other.
People are getting this message.
Why -- certainly hope so it makes sense to get your fiscal house in order.
And simplify eight you know that -- rules of the gained -- -- people can can actually invest.
-- -- businesses and create jobs leave it to the non politician of course they actually politicians actually will mess that up.
And that's a way I see it all births so -- but.
Do any of your colleagues get that I don't hear that from politicians are there -- many governors around the country that are doing exactly the same thing and and that actually you have to go to the state level to understand.
How you're supposed to -- -- garment.
And -- people called to a fascist and Nazi after the firings and we're very upset and -- last year hedging down 22 points behind -- likely opponent.
But this year Sears -- even then even.
-- convinced that.
If you -- the proper conditions.
Create the jobs in the private sector.
Lower taxes.
That that voters will color around and that that's exactly what's happening.
They won't come around right away people don't like firing I mean I do but normal people don't like -- -- government workers.
Ronald Reagan was unpopular at first wanting to shrink or doesn't -- your argument is over time they see results.
And that's at.
That's what voters.
Are looking for results I'll give you an attempt.
Our one of our main toll roads actually two of them.
They were not well maintained well that -- and and for served.
So we provided a forty year concession to a private.
Sector company a private profit making company of course.
Their toll roads look much better now.
Actually a well kept -- run by the private sector next month will do the same thing with our main airport.
We're doing it would.
Penitentiary facilities and -- and so forth even school construction and maintenance.
And are now being handled strictly a private sector.
Do a quick like a band they he's saying but it is not EC.
I am the first one to you know I actually real how easy it works it's better but it works yeah exactly that this doesn't work as well what exactly it works.
And and but not everyone is willing.
To take the risk.
Of not being on poplar.
Even if it's right thing to them thank you governor -- junior now.
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10Best Brunch
(Restaurants - Brunch)
100 Front St W, Fairmont Royal York, Toronto M5J 1E3 416-860-6949
Distance: ~40 m *
DOWNTOWN. As one of the Fairmont Royal York's dining rooms, EPIC is guaranteed to impress, whether at breakfast or brunch, lunch, or dinner. All meals are lavishly prepared by a skilled chef, and menus change frequently to capitalize on seasonal fare. Innovative dishes combine the best ingredients in exciting combinations for amazing outcomes. Enjoy attentive, first-rate service and delectable food this is the way life was meant to be.
(Restaurants - Brunch)
18 King St E, at Yonge St, Toronto M5C 1C4 416-861-9872
Distance: ~0.580 km *
DOWNTOWN. If you're searching for a place where food is in abundance and beer is plentiful, then look no further than Beerbistro. The place gives off a lively, bustling vibe, but that doesn't mean you can't relax here. A traditional bistro, the restaurant serves up some great European dishes. A bowl of tasty mussels in a steamy beer broth will grab your attention while other funky favorites like the lobster quesadilla are enticing too. A trip to the bistro isn't complete without digging into their special collection of German and Belgian-wheat beers.
Hot House Cafe
(Restaurants - Brunch)
35 Church St, Market Square, Toronto M5E 1T3 416-366-7800
Distance: ~0.760 km *
DOWNTOWN. Hot House Cafe's Sunday brunch buffet from 9:30am - 3pm includes traditional breakfast favorites, numerous pastas, beef and seafood specialties, a divine dessert table, plus an impressive salad bar. Accompanied by live jazz, it's a fun experience not to be missed. The rest of the week, the cafe satisfies hungry diners with hearty and innovative Italian pastas, gourmet pizzas, and an interesting range of International entrees such as an Asian chicken stir fry, Indian-style curried shrimp, and jambalaya. Plenty of creative vegetarian dishes, burgers, steaks, and a good selection of wine and cocktails, too.
User Rating:
/ 10
(Restaurants - Brunch)
328 Wellington St W, SoHo Metropolitan Hotel, Toronto M5V 3T4 416-935-0400 416-961-0055
Distance: ~0.832 km *
Sen5es Restaurant will be closed until September 2013 for renovations. The cafe and lounge will be open during renovations.
Appealing to all five senses through the judicious use of ambient lighting, a variety of textiles, earthy colors, sophisticated jazzy music in the background, and absolutely incredible food, this stylish 36-seat restaurant has earned raves as well as a bevy of adoring regulars. Savor intriguing Asian-tinged dishes such as prawn ceviche with citrusy yuzu juice, tea-soaked squab with an intriguing savory chocolate-ginger sauce, and roasted Arctic char with soy beans and a charming cassava-prawn gyoza. Senses also includes a bakery, café and gourmet food shop.
(Restaurants - Brunch)
461 King St W, Toronto M5V 1K7 416-598-4730
Distance: ~1.164 km *
DOWNTOWN. Brasaii's contemporary gray and white decor takes its cue from the 1920s-era black and white photographic prints that line the walls. When combined with fantastic traditional French cuisine, the effect is a stylish dining experience that just may make you forget you're in Toronto. Starters include all the traditional favorites: escargots in garlic butter, onion soup, steak tartare, and mussels. Featured main dishes run the gamut from steak frites to salade Nicoise with seared tuna. Daily specials are reliably good as well, and desserts are sublime try chocolate ginger truffle tart with caramelized mangos.
User Rating:
/ 10
Le Sélect Bistro
(Restaurants - Brunch)
432 Wellington St W, Toronto M5V 1E3 416-596-6405
Distance: ~1.211 km *
DOWNTOWN. At this authentic Left Bank-style bistro found in the Garment and Warehouse District, diners indulge in classic dishes like duck confit and cassoulet while enjoying the strains of jazz music. The frites are arguably the finest this side of the Atlantic. Be sure to try the tarte tatin comfort food at its finest. One of the best deals in town is Le Select's three-course prix fixe, available every night. Service is friendly and attentive; reservations are recommended.
User Rating:
/ 10
Gallery Grill
(Restaurants - Brunch)
7 Hart House Cir, University of Toronto, Toronto M5S 3H3 416-978-2445
Distance: ~2.258 km *
DOWNTOWN. A University of Toronto landmark, Hart House functions as the student centre. Inside the architecturally stunning structure is a world-class collection of Canadian art, and this much-lauded restaurant. Serving lunch and Sunday brunch only, the Gallery Grill has a brief but carefully designed menu, highlighted by fresh regional produce and flawless preparation. Start with the house cured duck prosciutto or a lovely local organic salad. Main courses include dishes such as organic salmon with Meyer lemon salad, and cassoulet with duck confit, lamb sausage and pork shank. The brunch menu leans more toward the lunch side with numerous options from their regular daily menu, but the frittata with roasted chestnuts, caramelized onions and cheddar is wonderful.
Bonjour Brioche Bakery Cafe
(Restaurants - Brunch)
812 Queen St E, Toronto M4M 1H7 416-406-1250
Distance: ~3.272 km *
EAST TORONTO. On a small corner in Leslieville, the little Bonjour Brioche Bakery Cafe brings the taste of a true French patisserie to life. Known most for its brunch menu options, Bonjour is a great choice whether you crave a piece of quiche or the sandwich du jour. And if dessert is more your thing, the aroma of delicious pastries makes it hard to stop with just one. From the service to the setting, everything is simple and relaxed.
Il Fornello
(Restaurants - Brunch)
576 Danforth Ave, Toronto M4K 1R1 416-466-2931
Distance: ~4.637 km *
EAST TORONTO. This is not your average pizza joint! You can choose from over 20 combinations or create your own from over 50 toppings. Of course, the familiar favorites are here pepperoni, mushrooms, olives but select something a little more unusual, perhaps escargot, capers, roasted garlic, pine nuts, and brie. Weekend brunch is popular too, featuring baked eggs, breakfast pizzas, waffles and other good stuff. Il Fornello is impressively aware of food allergies, even offering wheat- and gluten-free crusts, so don't be afraid to make special requests.
User Rating:
/ 10
Milestones Grill + Bar
(Restaurants - Brunch)
646 Dixon Rd, Etobicoke M9W 1J1 416-245-6262 877-439-1188
Distance: ~16.386 km *
AIRPORT. Casually elegant and trendy, Milestones appeals to folks who enjoy their comfort food on the "slightly adventurous" side. Although it's part of a small chain, the restaurant successfully avoids the cookie-cutter approach to atmosphere and decor, so each location has its own personality. The menu includes traditional favorites as well as more modern interpretations of classics. Start with spinach-artichoke dip or popcorn shrimp, or sample a steamy bowl of corn and potato chowder. Mains include everything from grilled steaks and seafood to Asian-style noodle bowls and smoked baby back ribs with cranberry corn relish. There's also a solid wine list and a bevy of tasty choices for vegetarians, carb-avoiders, and other health-conscious types.
* All distances are
"straight-line" distances.
for actual "travel distances."


text:
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Source: Materials (ISSN 1996-1944)
Dear Colleagues,
Investigation of the toxicity of nanomaterials is defined as "nanotoxicology", which came into being with the occurrence of term…
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You're watching...
What Obama's inaugural address reveals about his second term
Karl Rove weighs in
Jan 21, 2013
Karl Rove
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Karl Rove weighs in
Jan 21, 2013
Karl Rove
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A lot of candidate just moments ago president Barack Obama spoke to troops at the commander in chief ball where he addressed our servicemen and women serving at camp -- neck in Afghanistan.
Followed as you can see on the screen by the traditional dance between the president and the First Lady which you are now watching live now the celebrations in DC for this inauguration day will continue all throughout the night.
And we'll also be hearing later on this hour from vice president Joseph Biden -- just a few minutes you'll also be addressing our troops tonight so stay with us for that.
It was a long day of festivities continue.
I want -- begin with an analysis of the president's inaugural -- from earlier today because.
This speech in particular was very indicative of who this president is and where he wants to steer America as he now today begins his second term.
I think several things can be said it regards the address first it was the most partisan and divisive inaugural -- in living memory.
Now that was the -- -- year of unity and common purpose but it's always unity and common purpose as a means to an end.
And in the end what Obama defines his advancing his own left wing agenda -- time and time again.
In the speech there were also jabs not always direct but always obvious aimed at Republicans and conservatives in America and at one point in the speech today Obama said quote.
We cannot make absolutism.
Four principal or substitute spectacle for politics or -- name calling as recent debate.
-- -- -- was he referring to name calling like Republicans are social Darwin -- or members of the Flat Earth Society.
You know those guys that want dirty air dirty water and want kids with autism Down's syndrome the elderly all fending for themselves not wanting to feed hungry children.
Is that the kind of name calling that he's talking about.
When the charges his opponent and the 2012 election Mitt Romney of being responsible for the cancer death of the steelworkers wife is that the -- name calling.
Well of course not.
Obama was saying that it -- his opponents conservatives not him.
Who is destroyed civil discourse in America and who are rigid ideologues that of course.
In this case has things exactly backward and it's that kind of thing that has become almost second nature to this president and that is to portray his opponents as malicious inflexible dogmatic.
Now there's never such a thing as an honest disagreement with Barack Obama his opponents always need to be portrayed as evil forces in American life.
Now one other observation from today's inaugural address.
How extraordinarily.
Liberal the speech was more than any other inaugural dress in memory.
He used -- speech to advance his agenda and agenda that was addressing global warming championing gay rights gun control.
He also wants to protect Medicare Medicaid Social Security from any reform even though -- go bankrupt.
No matter how urgent and necessary those reforms are.
So what Obama was saying with the speeches -- I'm gonna protect all the liberal gains of the last century and terms of not doing anything to deal with entitlement programs.
And I got to try and break new ground in whole new areas global warming gay rights gun control.
-- make no mistake about it the president was signaling to liberal supporters to prepare for the battles ahead that means the conservatives you got to be prepared to do so as well.
In order to block as best you can Obama's efforts to transform America.
And while Americans all across the country grappled.
With a country that has sixteen trillion dollars in debt do you -- the president today talked about generational theft balanced budgets living within our means making tough decisions so America does not become grace.
About some part of transforming America.
Anyway here with reaction is our very own Fox News contributor the architect Karl Rove Sar.
-- like the music I like the dancing what you think of the speech.
I'm not impressed.
You know you -- -- greet him with your of your comments in the lead and there was one other thing that the president had kept fallen back on the east.
This habit of straw man arguments of suggestion that somebody's arguing -- in the nobody is really arguing for example.
No single person can train all the math and science teachers will need to equip our children for the future or build the roads and networks and research labs.
The will bring new jobs and businesses to our -- Couple who suggesting one person can do this.
What he's trying to say there is is you can't do it.
Communities can't do it businesses can't do it.
Groups of private individuals private sector -- do it we gotta give it all the wars and to do but but -- no one's making the argument that he was suggesting here's another one.
We reject the belief that America must choose between caring for the generation.
That built this country invest in the generation.
The will build a spiritual whose suggestion that Hussein let's take everybody's on Social Security Medicare today and -- over the cliff you know once again and complete straw man argument.
But I'll tell -- the thing that got me most about -- Shawn was.
The focus.
The focus what what does -- issue facing America today.
On this day fewer Americans are working that we're working in this country for years ago in the point where he really is -- eight point three down and -- the current rate of job creation it's gonna take his -- six more months.
Just to get back to that point in 2007.
When we went into the recession and in the meantime between 2007.
And twenties -- 2016.
-- -- -- We will have eight point six million more Americans enter the workforce without a job to find them we have.
For the first time in the history of a recovery a decline in the -- -- in the end the amount of the median family income.
We've had anemic growth the last four years -- zero point 4% on average the last three years that compare since World War II average growth of 3.2 percent.
And yet the president could barely bring himself always said is we got an economic recovery underway.
And what are the great challenges facing our generation is it to start the economy to make sure that every American has a prosperous life a prosperous future no the president said.
Here are our generation's Ted Ted -- tasks.
Equal pay for equal work I thought we got that done with that -- you know Ledbetter law you know gay marriage.
Which she was an incident -- -- against in his first campaign and during three of his first four years in office.
Voting protections you know I think this was a veiled attack -- Voter ID laws.
Immigration reform which he had a chance to do what he had.
Complete control the congress in 2009 and ten.
It didn't bother to do and gun control now are are all of these things gonna pass -- -- Democrat votes in 2000 -- Thirteen in 2014 know is as he got to get it got a gun control legislation is talking about where's the congress -- -- validate gay marriage I don't think so.
He couldn't get climate control when he was -- what he had complete control of congress do we now think it's gonna be pastoral with Republicans have controlled house no.
And as a result I think this was completely political and not focused on the big challenge the country faces which is get our economy going.
I really like what our colleague Charles Krauthammer said that this was an ode to big government and that he was declaring an end reaganism.
Which by the way you point out in the within that list there -- -- between gun control -- gay marriage global warming.
It's liking the ballot once a lock in every liberal agenda item but now advance it even further.
Will he be successful second terms and -- notoriously not successful.
Do you feel and look.
Let's -- -- global climate warming on your climate change what would she needs every we've already passed this through the congress it's done.
That is congress gonna pass this is part congress gonna tell the states know you can't -- -- -- voter ID laws.
It might pass immigration reform but only if he's -- partisan.
And doesn't L doesn't require immediate amnesty and citizenship gun control -- know I think the president was basically declaring.
His administration is no longer about substantive achievements it's about positioning about.
Making the Democratic Party.
Be more popular with his coalition and try and win the 2014 elections by making the Republicans look extreme.
And Republicans have got to respond not simply by blocking the bad stuff.
But by taking their strength in the house to pass positive items that pile up while maybe over the senate never to be really considered.
But give them an agenda a view that -- that says -- the American people he's over there worried about gun control were worried about getting jobs.
Kids over there worried about trying to gay gay marriage we want prosperity for your family.
Point three wouldn't million Americans at a labor force a big number -- none of these things debt deficits generational theft not mentioned as I said.
It's interesting -- had some people on the left today comparing this speech that Gettysburg address.
Which I found it somewhat amusing.
And you know we're on the -- references to the -- She's so I can't believe -- caught up the media gets in these moments is actually comical.
But I wanted to ask you for the speech itself.
I felt it was a hodgepodge of of ridden by people that wanted to come up with -- ask not what your country can do for you but what you can do for your country moment.
And when you write a speech that way isn't it likely to fail.
You have to use your own words and what they did was they created a lot from Abraham Lincoln I saw at least three Lincoln's speeches in there.
They had they drew from the house divided speech when they said.
Nation based on liberty and equality could not.
-- realized it couldn't be had remained half free half slave that's from.
-- almost -- the word for word from the house divided speech the Gettysburg address showed -- word for word wherever republic.
A government of the people by the people and for the people.
And we had to deal Lincoln's famous.
Message to congress and 1862 before the emancipation proclamation where said as we think -- we must as our case is new so once we think -- -- to -- But look he -- you don't become.
You know big rhetoric by simply copying the words of somebody else you have to have a big original thought.
Charles was right this was a declaration of political liberalism is back in all its glory but he couldn't bring himself to say the -- big government is over -- -- a memorable phrase dinner -- idea that this is all about.
Expanding government and given Washington more power our -- stay right there.
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text:
Axeda, the cloud-based M2M management company, today announced the appointment of Todd DeSisto as President and CEO. The news comes as Axeda closed a $12 million round of funding led by JMI Equity, a long-term supporter of Axeda, as well as Wipro Ltd. and Mitsui & Co.
DeSisto has held executive roles in finance and operations with private companies including Network Intelligence, New River Inc., Hawaiian Wireless, Atlantic Cellular Company and Aloha Partners. Prior to joining Axeda, DeSisto served as CFO and COO of Axeda.
In a press release, Axeda said the most recent round of funding follows a record quarter of new customer growth. The company said it has added more new customers in the first half of 2013 than in all of 2012.
All told, the Axeda Machine Cloud now manages nearly 1.3 million assets.
Axeda will take on Mitsui USA as a strategic business partner. The companies will work together to expand Axeda's geographical footprint and customer base by identifying and expanding sales and business development in Asia-Pac.


text:
Posted 08 February 2012 - 12:53 PM
this comes from a CDC report.
I was somewhat surprised. i used to bake bread regularly but not at the moment. most of the bread i use for toast/sandwich/pasta-related comes from this bakery Nashoba:
I get the version they sell to trader joes as its the same as their sourdough just a buck cheaper for some reason as its delivered frozen and defrosts overnight on the shelf.
it has 340 mg sodium/50 grams ie 4080 mg sodium/loaf at 21 oz.
if you bake your own, what is the sodium/baked loaf that you make ie the sodium ( not NaCL ) per loaf and the weight of the backed cooled loaf?
its a certain amount of work to figure this out but Im interested in restarting my baking not for the above but because 'its about time'
Im thinking of going with the "Five minute loaf" thread.
some time ago in CA there were many locally baked sourdoughs to choose from in the bay area. one was from Nancy Silverton La Brea bread, baked locally and sent frozen to these stores. it was better than the others, and I noted it had more sodium in it.
Im only curious about the Home Loaf. it may be similar to commercial or not. if it is then one cuts down on the sodium elseware.
PS 1 tsp 'salt' = 2400 mg sodium
Posted 08 February 2012 - 01:08 PM
the last breads I used to bake came from "THe Best Bread Ever" by Chas. Van Over
a loaf 'wet' came to 815 grams (water and flour) and had 10 gms of salt ie 4000 mg of sodium
this was 'wer' not baked.
Posted 08 February 2012 - 01:20 PM
Based on the above, the bread recipe I've created through trial and error happens to use 12 grams of Kosher salt (which is a different density than table salt); or, salt is at a baker's percentage of 2%.http://www.saltinstitute.org/About-salt/Salt-FAQs
[...] A simple summary is that about six grams of salt makes a level teaspoonful and just under 2.4 grams is sodium. This is exactly correct for salt with a density of 1,217 g/L. Based on a salt density of 1,250 g/L, one level teaspoon contains approximately 6,200 mg NaCl and approximately 2,400 mg sodium.
The "wet" weight of my bread is approx. 1,075 grams, and the final baked weight usually comes in at an even kilo...
I assume that the total amount of sodium per loaf is in the neighborhood of 4,800 mg.
So I got that goin' for me, which is nice.
Posted 08 February 2012 - 01:43 PM
similar to the bread i used to bake.
Posted 08 February 2012 - 05:08 PM
Posted 09 February 2012 - 05:59 AM
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text:
Technology follows a different path in Africa as in the West, due to poverty. The mobile phone has become the most widely used tool of communication, with still-expensive computers lagging behind. According to a report published by the French Institute of Foreign Affairs (IFRI), there were 246 million mobile line users in 2008. (…) The growth rate of the mobile market and the Internet in Africa is two times bigger as the global average.
The mobile phone technology is creatively used by health programmes, weather forecasts, to control the price of goods and to access banking services.
A tool of prevention and medical assistance
The AIDS epidemic in Africa is still dramatic, with many HIV-positive people not having access to any kind of treatment. Cell Life is an initiative developed together by the University of Cape Town and the Peninsula University of Technology with the aim of improving the lives of the people infected with the HIV, with the help of the mobile phone technology in South Africa.
The areas worst affected by the HIV suffer from a lack of qualified health professionals. Cell Life uses mobile telephones to put in contact professionals and patients so they can communicate information about the treatments. Each doctor or nurse can thus give advise remotely to about 20 patients. There are other diseases that can be equally fought off in this way: This system of health care through mobile communication has helped to impede the propagation of Typhoid epidemic in Uganda too.
Widely accessible weather forecasts
The initiative 'Weather forecasts for everyone' was launched in June 2009. In Africa there is an important lack of weather stations and monitoring, so the weather forecast coverage is 8 times lower than the minimum recommended by the World Meteorological Organization. There is a sense of urgency in solving this problem: The climate change affects directly the daily life of farmers, who need accurate weather information in order to prepare themselves against potential problems. The project 'Weather forecasts for everyone' counts with the help of the World Humanitarian Forum, Ericsson, the World Meteorological Organization and the Telecom Zain. They will install more than 5000 meteorological autonomous stations and transmit the data collected with the help of mobile telephones. The initial deployment has already started and is concentrated in the areas of the South of Kenya, Tanzania and Uganda.
A useful way of managing prices in the agricultural market
The cellphone allows farmers to know the prices of agricultural products firsthand and avoid middle men by selling directly to the consumer. Mobile phones help also increase revenues while reducing the final price for the consumers. In Kenya this service is provided in the cereals market by the DrumNet network.
Mobile banking
In the rural regions of Africa, access to traditional banking is heavily limited. This means that a big number of people can only use cash as a method of payment, which not only is less convenient but also limits their business opportunities. Mobile phones help change this reality by offering the users a way to access banking services through mobile networks.
More specifically, mobile banking allows the users to make bill payments, transfers, deposits and withdrawals. These orders are done by SMS, with PIN codes to authenticate the transaction authors.
In the cases of Congo and Zambia, customers can use their cellphones to pay their bills. The customer opens an account with Celpay and then can make payments by sending SMS to Celpay, which in turn transfers the money to the merchant's account.


text:
Dean Hall and friends have been keeping busy with the upcoming DayZ standalone alpha, which they plan on releasing on Steam Early Access sometime… in the future, but before that happens, Hall wants to make sure we keep our expectations relatively low. "I really can't… Read More
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