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Memory Reactivation
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by memoryreactivation in Memory Reactivation
When I started learning about immunology I held a conviction that the immunity serves only to combat infections and pathogens. Perhaps the major change I have acquired in my understanding of immune processes is that the function of the immune system could be more permeating and extend to broader activities than just the defense. What we call [...]... Read more »
Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP.... (2013) Direct control of hepatic glucose production by interleukin-13 in mice. The Journal of clinical investigation, 123(1), 261-71. PMID: 23257358
by memoryreactivation in Memory Reactivation
Schistosomes are parasitic worms that live in the blood and have a complicated life cycle. The sexual form inhabits vertebrates (humans included) whereas the other stages infest fresh water snails. Adult worms tend to chronically infect theirs host (sometimes for many years) but for the propagation they have to be able to release their eggs to the [...]... Read more »
Joseph D. Turner,Priyanka Narang,Mark C. Coles,Adrian P. Mountford. (2012) Blood Flukes Exploit Peyer's Patch Lymphoid Tissue to Facilitate Transmission from the Mammalian Host. PLOS Pathogens. info:/
by memoryreactivation in Memory Reactivation
I have found a short paper on the potential mechanism how HIV virus may be transmitted between mother and child. I think it is interesting because it not only provides the information which may be useful for a given pathology but it also poses some questions as to the basic immunology processes. The main theme of [...]... Read more »
Bunders MJ, van der Loos CM, Klarenbeek PL, van Hamme JL, Boer K, Wilde JC, de Vries N, van Lier RA, Kootstra N, Pals ST.... (2012) Memory CD4 CCR5 T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1. Blood, 120(22), 4383-90. PMID: 23033270
by memoryreactivation in Memory Reactivation
Only the relatively small part of mammalian genome is formed by protein-coding sequences. The long stretches between these protein-bearing fragments contain other components which are either non-transcribed regulatory elements or the variety of non-translated RNAs many of which are also taking part in the regulation of gene expression. This intricate network influences the decision whether a given protein [...]... Read more »
Espeli, M., Clatworthy, M., Bokers, S., Lawlor, K., Cutler, A., Kontgen, F., Lyons, P., & Smith, K. (2012) Analysis of a wild mouse promoter variant reveals a novel role for Fc RIIb in the control of the germinal center and autoimmunity. Journal of Experimental Medicine, 209(12), 2307-2319. DOI: 10.1084/jem.20121752
by memoryreactivation in Memory Reactivation
Some areas of our body enjoy a special status as far as the immune reaction is concerned. Anatomical entities like the gut or female genital tract as well as other mucosal surfaces do not support the same extend of protective response compared to many non-mucosal tissues. This exclusion is crucial to avoid the unwanted inflammation in [...]... Read more »
Shin H, & Iwasaki A. (2012) A vaccine strategy that protects against genital herpes by establishing local memory T cells. Nature, 491(7424), 463-467. PMID: 23075848
by memoryreactivation in Memory Reactivation
It was long known the absence of the gut microbiota impairs the full functionality of mammalian immune system. However, it appears that the immune system may require the species-specific microbiota not just any microbiota to develop its proper responses as the recent publication indicates. I think that this report has important implications both for the better understanding of [...]... Read more »
Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR.... (2012) Gut immune maturation depends on colonization with a host-specific microbiota. Cell, 149(7), 1578-93. PMID: 22726443
by memoryreactivation in Memory Reactivation
How monkeys or apes respond to the challenge of lentiviral immunodeficiency viruses varies across different primate species. Some primates like rhesuses are similar to humans because following SIV infection they develop the AIDS-like disease with all the characteristic features of progressive immune destruction. However, there are other species that do not display such aggravated pathology. African sooty mangabeys are the best studied [...]... Read more »
Vanderford TH, Slichter C, Rogers KA, Lawson BO, Obaede R, Else J, Villinger F, Bosinger SE, & Silvestri G. (2012) Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation. Blood, 119(24), 5750-7. PMID: 22550346
by memoryreactivation in Memory Reactivation
I have found the publication that focus on pretty much unexplored subject which is the presence and role of commensal fungi in the mammalian gastrointestinal tract. As far as I know there is no information on whether the intestinal fungi community (similarly the bacterial microbiome) has any influence on the basic metabolic functions of their hosts. The discussed paper does not provide such knowledge either.... Read more »
Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M.... (2012) Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science (New York, N.Y.), 336(6086), 1314-7. PMID: 22674328
by memoryreactivation in Memory Reactivation
When a B cell starts releasing antibodies at the large scale it undergoes the sequence of deep morphological and physiological changes. It expands its cytoplasm and switches on the machinery that lets it cope with the enhanced protein production in preparation to professional antibody secretion. On the molecular level this transition it governed by the onset in expression of [...]... Read more »
Yasuda T, Hayakawa F, Kurahashi S, Sugimoto K, Minami Y, Tomita A, & Naoe T. (2012) B cell receptor-ERK1/2 signal cancels PAX5-dependent repression of BLIMP1 through PAX5 phosphorylation: a mechanism of antigen-triggering plasma cell differentiation. Journal of immunology (Baltimore, Md. : 1950), 188(12), 6127-34. PMID: 22593617
by memoryreactivation in Memory Reactivation
During the inflammatory reaction to an invading pathogen neutrophils arrive at the injury site and leave blood vessels to accumulate around foreign particles. The publication I am discussing today analyzes how neutrophils migrate through the layer of pericytes that coats endothelial cells. Pericytes are cells that form the important structural part of certain types of blood [...]... Read more »
Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, & Nourshargh S. (2012) Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. The Journal of experimental medicine, 209(6), 1219-34. PMID: 22615129
by memoryreactivation in Memory Reactivation
Who are the most accomplished immunologists in the world? The title may go to several pathogenic organisms that are apparently able to manipulate immune responses and do it in the way that puzzles many researchers. Bacterium Borrelia burgdorferi (the causative agent of Lyme disease) definitely belongs to the elite club. I have learnt that during infection [...]... Read more »
Hastey CJ, Elsner RA, Barthold SW, & Baumgarth N. (2012) Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection. Journal of immunology (Baltimore, Md. : 1950), 188(11), 5612-22. PMID: 22547698
by memoryreactivation in Memory Reactivation
I like reports that make me learn something new and appreciate novel developments leading to more integral view of immunological concepts. My understanding of the thymic central tolerance process was that thymocytes receiving strong signals from tissue antigens through TCR undergo invariably the clonal deletion. But it looks like the clonal deletion of cells that can develop [...]... Read more »
Pobezinsky LA, Angelov GS, Tai X, Jeurling S, Van Laethem F, Feigenbaum L, Park JH, & Singer A. (2012) Clonal deletion and the fate of autoreactive thymocytes that survive negative selection. Nature immunology, 13(6), 569-78. PMID: 22544394
by memoryreactivation in Memory Reactivation
The main task of B cells is to release protective immunoglobulins. Yet it is not their only role since they are apparently capable to take on the diverse array of activities that do not directly form a part of effector humoral responses. Instead of just secreting antibodies B cells can influence the outcome of an [...]... Read more »
Barr TA, Shen P, Brown S, Lampropoulou V, Roch T, Lawrie S, Fan B, O'Connor RA, Anderton SM, Bar-Or A.... (2012) B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells. The Journal of experimental medicine, 209(5), 1001-10. PMID: 22547654
by memoryreactivation in Memory Reactivation
Over last 10 years few subjects in immunology have received more attention than regulatory CD4 T cells called in abbreviation Tregs. Tregs are considered to have the potent suppression activity over adaptive immune responses and their lack may result in the autoimmunity development. The central trait pertinent to Tregs is the expression of the transcription factor Foxp3. The essential role of Foxp3 [...]... Read more »
Rivas MN, Koh YT, Chen A, Nguyen A, Lee YH, Lawson G, & Chatila TA. (2012) MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice. The Journal of clinical investigation, 122(5), 1933-47. PMID: 22466646
by memoryreactivation in Memory Reactivation
We never walk alone; each of us is colonized by scores of bacterial species that live in our gastrointestinal tract. The colonization event occurs right after birth and has profound effects on our immune system – this sentence appears in every modern immunology textbook. There is, however, no such thing like one human microbiome as [...]... Read more »
Lundell AC, Björnsson V, Ljung A, Ceder M, Johansen S, Lindhagen G, Törnhage CJ, Adlerberth I, Wold AE, & Rudin A. (2012) Infant B cell memory differentiation and early gut bacterial colonization. Journal of immunology (Baltimore, Md. : 1950), 188(9), 4315-22. PMID: 22490441
by memoryreactivation in Memory Reactivation
The May issue of Nature Immunology contained an article that has described an intriguing mechanism of tolerance to microbiota without losing the ability to detect invading intestinal pathogens and switching on protection mechanisms when it comes to the defending. According to that report macrophages residing in the colon (but not from the bone marrow) remain hyporesponsive to TLR [...]... Read more »
Carvalho FA, Nalbantoglu I, Aitken JD, Uchiyama R, Su Y, Doho GH, Vijay-Kumar M, & Gewirtz AT. (2012) Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges. Mucosal immunology, 5(3), 288-98. PMID: 22318495
by memoryreactivation in Memory Reactivation
The studies on human population infected with or exposed to HIV have brought the description of several virus-refractory phenotypes. Among them are long-time non-progressors and HIV exposed seronegative persons. The first group is able to control virus replication without the anti-retroviral therapy, maintain the normal CD4 T cell number and avoid the chronic immune activation [...]... Read more »
J Lajoie1, J Juno1, A Burgener1, S Rahman1, K Mogk1, C Wachihi2, J Mwanjewe1,2, F A Plummer1,3,4, J Kimani1,2, T B Ball1,3,5 and K R Fowke. (2012) A distinct cytokine and chemokine profile at the genital mucosa is associated with HIV-1 protection among HIV-exposed seronegative commercial sex workers. Mucosal Immunology. DOI: 10.1038/mi.2012.7
by memoryreactivation in Memory Reactivation
The diet, previous or ongoing encounters with infectious organisms and parasites as well as bacterial microflora that inhabit the intestinal tract or other mucosal surfaces – all these factors influence the quality of immune responses. To mention just one relevant case – in developing countries people appear to be less affected by autoimmune diseases but [...]... Read more »
von Schillde MA, Hörmannsperger G, Weiher M, Alpert CA, Hahne H, Bäuerl C, van Huynegem K, Steidler L, Hrncir T, Pérez-Martínez G, Kuster B, Haller D. (2012) Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines. Cell Host. DOI: 10.1016/j.chom.2012.02.006
by memoryreactivation in Memory Reactivation
Follicular helpers are the special population of CD4 T cells that localize to germinal centers and are involved in enhancing the humoral response. They are distinguishable from other CD4 T cell subsets by their joint expression of CXCR5, ICOS, PD-1 and the transcription factor Bcl-6 as well as the capacity to secrete IL-21 cytokine. The recent paper [...]... Read more »
Lüthje, K., Kallies, A., Shimohakamada, Y., Belz, G., Light, A., Tarlinton, D., & Nutt, S. (2012) The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nature Immunology, 13(5), 491-498. DOI: 10.1038/ni.2261
by memoryreactivation in Memory Reactivation
Th17 response has is the ability to induce migration of neutrophils from the bloodstream into inflamed tissues. Neutrophils form the important part of immune defense and as such are equipped with a number of anti-microbial and pro-inflammatory measures. However, as in the case of other immune effectors their action may also have the darker side [...]... Read more »
Eskan, M., Jotwani, R., Abe, T., Chmelar, J., Lim, J., Liang, S., Ciero, P., Krauss, J., Li, F., Rauner, M.... (2012) The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss. Nature Immunology, 13(5), 465-473. DOI: 10.1038/ni.2260
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Join the conversation about climate change with some of the most engaging and influential voices on Twitter.
Sealing up air leaks and adding insulation are easy to do and offer big rewards in terms of reducing greenhouse gas emissions and saving money. Get started with a home energy audit to help you evaluate the over-all energy efficiency of your home.
Your home might be inhabited by energy vampires —electronic devices that are ready to operate and receive signals at all time. Even when turned off, these devices are silently sucking away precious energy. Make sure your cell phone and laptop chargers, music players, power tools and other devices are unplugged when not in use. Learn more about how to stop energy vampires.
Make friends with CFLs (compact fluorescent lights) and you can significantly reduce your city's carbon footprint (and save some money). If everyone in the US alone changed their five most-used lights to CFLs, it would prevent the equivalent of green house gas emissions from 10 million cars. Learn more about CFLs.
According to The Worldwatch Institute, the ingredients of the typical Swedish breakfast—coffee, cream, sugar, bread, butter, cheese, orange juice and apples — travel a distance equal to the circumference of the Earth before reaching the table. Buying locally-grown food not only helps improve local economies, it saves significant amounts of energy. One big plus: local food is usually much fresher. Read: Is Local Food Better? (Worldwatch Institute).
Buying products without excess packaging and bringing your shopping bags reduces energy usage and keeps excess waste out of municipal landfills and our oceans. In 2009, the Ocean Conservancy found that plastic bags were the second most common type of waste found in international waters. Get the facts on waste.
While hybrids, electric cars and smart cars are temptingly green, it might actually be more energy efficient to keep your older-model car on the road while it's in good condition. Every car creates a large carbon footprint when manufactured - even a hybrid. Read: Buy a New Car or Keep the Old?
Well-maintained cars are more fuel-efficient and produce less greenhouse gas emissions. Simple actions like using the manufacturer-recommended grade of motor oil can go a long way in improving your car's efficiency. Keeping tires properly inflated can significantly improve fuel efficiency as well. For more information, go to the U.S. Department of Energy's Fuel Economy's website.
Walking, biking and public transit are all far better options for getting around the city than driving. Encourage your employer to offer better commuter benefits such as public transportation passes, bike racks and in-office showers. Get tips for city-friendly bike programs.
Washers and dryers are enormous energy hogs. By switching laundry time to after 9pm, which is off-peak for many energy delivery systems, you lighten the load on your local system and save money since the cost of energy at this time is lower. Try using cold water for washing clothes, since heating water also uses a lot of energy. Get more information about off-peak energy usage.
Green lawns and exotic species may look pretty, but they can take an enormous toll on municipal water systems. Planting native species around your home or business saves water and energy for your city. Not only are you eliminating the carbon used to ship non-native plants, you're also reducing water usage since the plants will probably grow better without extra help. Green plants are also a good way to offset carbon. Get the facts on native plants and beneficial landscaping.
We can all reduce the pressure on our cities by consuming less, reusing what we can, and recycling the rest. Read the EPA's best practices on the three R's of waste management.
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Neither. Endure and live to fight another day.
We are flying our American Flag in ´distress´ mode to make a statement. Feel helpless and outraged - more about the ´low information´ ignorance and media complicity seeming to overpower the (hopefully) millions of us who know and believe otherwise!
Mourning leads to resignation. I am resigned to fight this clown and his power grabbing ways any way I can.
Pray, God save the republic...
Neither. Hunkering down for a long, dark winter.Realizing their are no heroes, and we´ll just have to replace everyone of of these traitors to get on the right path.
Neither. I´m still shocked and awed by Michelle´s new weave with wow-that´s-amazing bangs./s
I mourn for the ignorant masses.
Ignore it.
Would rather listen to a cat hock up a hair ball than bo but just because it´s a bad day doesn´t mean that we won´t ever have good days again. There are so many good citizens still out there and Lucianne reminds me of that every time I read it. Thanks to all of you.
"He who sits in the heavens laughs"! I´m only mourning that my kids, and if they are blessed to have kids of their own, will have to suffer the consequences of this man and his congress´s actions.We are free in Christ, that´s what matters.
Ignored it.Went to the range and fired off a couple of hundred rounds in honor of the 2nd amendment, and then went home and had a beer.Definitely did not turn on the TV all day. Just couldn´t handle watching our republic being killed all that much more...
Is this a trick question?
I have not yet begun to fight!
I think one of Conservatives New Year´s resolutions should be: to make absolutely certain that everyone in America---even school kids---know exactly what is the Cloward-Piven strategy, and how it is at work today. It explains nearly every evil scheme, program, misdeed and treasonous crime of the Tyrant Hussein.
You mean there was an inauguration?
I will mourn that this country re-instated a Third World Dictator to the White House. I will celebrate that those same people will suffer for it and rightly so.
They know not what they do!
Mourning in America


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Mammograms are probably the most important tool doctors have not only to screen for breast cancer, but also to diagnose, evaluate, and follow people who've had breast cancer. Safe and reasonably accurate, a mammogram is an x-ray photograph of the breast. The technique has been in use for about 40 years.
Screening mammograms should be performed annually beginning at age 40 to check the breasts for any early signs of breast cancer. Diagnostic mammograms are different from screening mammograms in that they focus on getting more information about a specific area (or areas) of concern — usually due to a suspicious screening mammogram or a suspicious lump. Diagnostic mammograms take more pictures than screening mammograms do. A mammography technician and a radiologist would coordinate to get the images your doctor needs to address that concern. The technician may need to magnify a suspicious area to produce a more detailed picture that will help your doctor make the diagnosis.
In this section, you can read more about mammograms, including the following topics:
- Breastcancer.org Mammogram Recommendations
- Mammography: Benefits, Risks, What You Need to Know
- Mammography Technique and Types
- Where to Get a Mammogram
- What Mammograms Show: Calcifications, Cysts, Fibroadenomas
- How Doctors Interpret Mammograms
- Mammogram Results: Breast Imaging Reporting and Database System (BI-RADS)
- Mammograms after Different Types of Breast Surgery
- Take the "I Am" Pledge


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You're watching...
Sheen pays Lohan's taxes?
Lohan gets $100K for back taxes from fellow former wild child
Nov 26, 2012
You're watching...
Lohan gets $100K for back taxes from fellow former wild child
Nov 26, 2012
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I'm actually to bargain with today's box or one I'm not content entertainment news groundout Hollywood -- can be generous when it comes to cutting big tax.
But it's usually not to one another -- in the report's Charlie Sheen -- given Lindsay alone and 100 grand to help actress pay off back taxes.
Lohan reportedly -- over 200 grand for 2009 and 2010.
Friends tell the -- the two became friends upcoming scary movie five -- from more of the story and that's one.
As the post is reporting up by a heating up in the world of celebrity -- As Anthony boarding call Gordon -- these moved to register our US restaurant's name in the UK quote shameful at addict.
He expressed these thoughts on Twitter of course.
-- -- filed a motion to trademark the name that spotted pig in London just one catch the name already -- for New York restaurant not only by Ramsey.
The owners of the New York establishment haven't -- -- fun.
But board dean among other TV shots are responding.
-- what they're saying online today then.
Start them -- and I'll never got the -- don't living up to their Lira as they kick off the first of five concerts to mark their fiftieth anniversary.
The show at London's O two arena lasted two and a half hours.
Mick Jagger and Keith Richards both spend their banks to -- They ran a tribute video had guest stars jammed out their greatest hits and poked fun at their pricey ticket.
I don't -- -- count on fox or 11 today and see weapons storage they get ready to rock states diet thanks for collecting.
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just moved to reblog a hiddles-post on my dash
realized i couldn't because it was my post
is this is my life now?
Posted on June 17, 2012 (♥ 1)
+ help me + i have a serious problem + serious + when i was younger + my best friend was going to buy me swearing therapy + in exchange for me buying her psychological therapy + but now + i need post-hiddleston therapy + anyone prepared to fund that? + just five pounds a month could save an izzy from EOS + exploding ovaries syndrome + it is a serious problem + the life and times of izzy


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117 Reviews
Fabric Composition
For full terms and conditions please see our Delivery & Returns policy
12/08/2013 07:07:23
It's the pricing that's key. Basically, anything on an offer is the correct price. Anything else is just biding time till the right season then it comes down to the correct price showing an Alledged massive saving. The truth is I've bought a couple of outside jackets for £29.99 .... Not bad at all. But it's unlikely that anyone would pay £119.99 for the same item? Is it?
25/07/2013 00:01:35
Tried this on when I got home from work after purchasing it during my short break. Felt like it would be great for keeping cool and dry, but unfortunately found the body length to be a bit short for my long back. Returned it for similar item with longer body.
18/01/2012 17:21:44
very comfortable to wear, as it is soft and light, it ialso gives the wearer freedom to move and manages to keep you warm on cold occations and is breathable when you start to respire in more challenging situations. overall a great purchase!
20/10/2013 09:52:27
Arrived well within estimated delivery time. Perfect for cycling and running. Nice bright colour so able to be seen at night. Would have liked more range of colours at this price though. Prices cheaper than in store.
14/01/2012 14:33:07
Ideal as a base layer worn under a fleece when out hiking, also works well as a running top. The moisture wicking feature makes this a far more comfortable option than a cotton t-shirt. Good range of colours.
01/02/2012 14:57:51
i have a few of the Cool Max type T shirts. I do a lot of walking and find they are comfortable, good at wicking perspiration, easy to wash and are quick drying without the need to iron.
05/08/2013 19:45:34
Took this on holiday to Turkey, withstood 40c+ heat and no sweat stains. Really impressed at the quality..so much so that i have odered two polo tops from the website for golf :-)
07/10/2013 09:36:09
It's actually yellow. Nevertheless the shirt is excellent. I bought it as base level, but ended up using it casual / sport also. Very comfortable and nice looking. Thanks.
12/10/2012 12:41:16
Much better quality than I expected for the price. I do a lot of cycling in my spare time and this shirt is very comfortable to wear. I am very pleased with the product.
10/06/2012 13:46:00
Bought as a good weather cycling top. Hi-vis colour sheme is ideally suited to this purpose. Fabric is comfortable to wear and appears to wick moisture effectively.
27/12/2012 16:03:41
I have worn this while walking along the Cornish Coastal Path and it has kept me feeling comfortable in all that the great British weather has to offer
18/05/2012 11:53:59
A very versatile garment. I intend to wear it for cycling, but it could be used as a base layer, or an outer layer, for a wide variety of activities.
02/08/2012 08:37:50
Superb safety colour for my cycling and road running. Seems to have a slight smell but hopefully this will disappear once washed a couple of times.
01/08/2012 15:44:39
bright colour was the main attraction to this article as it is great for early morning commute cycle rides . A bit like a high visibility jacket
24/01/2012 20:47:46
Another sale item at a very good price. Although this type of material tends to 'snag' it is very lightweight, easy tp pack & dries quickly.
08/12/2011 19:31:03
This Tee shirt is nice and slinky, feels good, and is made from breathable material so it is good as an underneath layer for the outdoors.
16/02/2013 18:04:50
I bought 2 of these to wear under heavier shirts as a base layer whilst running and they are excellent ..... keeping me both warm and dry.
01/07/2013 09:10:07
Great style, generous size, lovely material. Great for running & cycling. I normally buy medium but got small for a nice snug fit.
28/02/2012 13:52:00
24/09/2013 20:25:48
Bought as a base layer to be worn under long sleeved V-Neck Tee shirt. I'm confident it will do the job on cooler days.


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Mobile Worker: Does it Work for You?
The Wall Street Journal's Sarah Max just did a piece on the rise of mobile workers and the challenge of staying connected. One company runs its annual meeting completely online with a employees doing everything you'd normally do at an annual meeting - from schmoozing over a muffin to raising a hand to comment – online. "The CUNA Mutual team is outfitted with webcams and Cisco's WebEx, a software program that allows users to see as many as six other people at a time on their computer screen, share desktops and 'raise their hands' to speak."
Working from Los Angeles for Herman Miller – who are based in Michigan – I often phone in for meetings. And as Max points out in her article, you don't always feel as tight a part of the team as the people in the room. But there are simple solutions. Often it's as easy as turning up the volume on the phone so you can hear all the participants a little better. And visits to head office a few times a year are essential for building connections with the people you work with directly. One thing Max didn't mention was the power of email. A quick note sent to someone after a meeting just recapping can really help reconnect to a project.
We'd love to hear how you stay connected? What works for you?


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Photos of Toddlers Tasting Lemon For the First Time
By Ieva • Aug 15th, 2013 • Category: Funny, Latest Posts, PhotographySadly, most of us can't remember our reactions to most of the new things when we tried them for the very first time. In order to capture some of these first experiences, photographers David Wile and April Maciborka pictured toddlers tasting lemon for the first time. The bitter fruit, that even adults might be sometimes reluctant to taste, called out the most genuine reactions from all of the kids, going from disbelief to shock or betrayal.


text: Well the specialty group restaurants are know to offer some of the best dining experience in Kolkata but Machan was something I stayed away till recently. Probably due to the creepy (I later found it actually enjoyable) environment. It is good for something after all. Contrary to many would believe I feel this place server some best Biryani (Mutton) you... More


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Rabbit Care Sheet (pdf)
Holding a RabbitRabbits get hurt easily. Pick your pet up carefully and support his/her hindquarters. Your parents should always be around when you hold or play with your bunny.
Always Watch Your Rabbit When you take your rabbit out of his/her cage, always watch him/her. If left alone, rabbits will chew and destroy anything.
More Than One Rabbit?Avoid adopting two males. Males usually fight. If you decide to adopt more than one bunny, get two females or a neutered male and a female.
Keep Your Rabbit Indoors It's best to keep your rabbit indoors. Your pet wants to be around you and your family. They could also be harmed by predators like coyotes if left outdoors.
The Right TemperatureRabbits are very sensitive to heat. They should be kept in temperatures less than 80 degrees F. You may want to move them down to a cool basement in the summer if it's too hot.
Neuter or Spay Your BunnyTo prevent health problems, females should be spayed and males should be neutered when they are at least four months old.
You know your rabbit best. If he/she seems to be acting strangely, call your veterinarian.
Information about taking care of your rabbit provided Monique Weldon, DVM of the Coal Creek Veterinary Hospital, Centennial, Colo.
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I've been planning to create and account here in LB for so long. At last, I gathered all my guts: here comes my very first look that I will post here in LB. HYPE if your inspired. thank you


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Concussions in football are reaching a critical stage. Players, especially in college football, are getting bigger and faster at a rate that helmet technology seems unable to keep up with. Force equals mass times acceleration. Get something big enough moving fast enough and run it into a person, and you generate more force that we can disperse and shield someone's head from.
Now though, a new problem is coming up. A study has raised the potential that football is becoming so violent that you do not need to suffer a concussion to experience the long term effects:
The scans of the injured player showed as much damage as his teammates who endured routine levels of contact, suggesting to Bazarian and Zhong that extreme hits that made athletes' vision foggy and eyes starry – telltale signs of concussions – weren't necessary to cause damage to their brains. Instead, it suggested the hits players endured play-to-play and week-to-week could accumulate and affect the brain's health. Imagine linemen colliding after each snap, a running back getting bumped while powering through a hole, or linebackers finishing off a play. Those plays – the bedrock of game action – could be adversely affecting a player's health over time, the results suggested.
The science here is just getting started, but if this research is confirmed and reveals a widespread problem, there would need to be a fundamental change in how football is organized. Rules to prevent head-to-head collisions are of limited value if big hits are only part of the problem. One option would be to remove routine contact from football, but at that point it would be a different sport.
Instead, the challenge should be to look for ways to mitigate this damage caused by regular jostling. One common sense idea would be more rest in between games. But to have more rest, you need either fewer games or a longer season. A slightly longer season would yield another bye week or two, but what if the idea of a football season played in the fall was thrown out in favor of one played over the entire academic year?
A season played over the entire academic year would also mean changing practice limits. 20 hours of athletic activity over six days a week would be quite the grind over an entire academic year. The limits would have to be somewhere between the in-season limits and the offseason limits, something along the lines of 15 hours per week, maximum of 4 hours per day, and two required off days per week. Hopefully a longer season also reduces the pressure on student-athletes to engage in voluntary activity, which adds on another 20 hours for the average FBS student-athlete.
A competition schedule might have teams playing every other week, with the occasional game on back-to-back weeks and/or two weeks off (so half of the teams aren't one schedule and half on the other). Even with a playoff that adds games beyond the current maximum of 14, there would be periods of extended rest.
A number of ancillary benefits are possible as well. A steady practice schedule that includes fewer hours per week of athletic commitments could help academics. A longer season frees up television slots on the weekend, reducing the number of midweek games. With games every other week, coaches might have better work-life balance and more time to recruit.
Tradition would definitely be thrown out the window and there's a chance that year-round college football would not be as great a commercial success as it might seem given the public's seemingly insatiable appetite for the sport. But if we're serious about the health and welfare of student-athletes, any idea that maintains the core of the sport and reduces long-term damage needs to be explored.
These ideas are a long way off though. First more study is needed to confirm this phenomenon and measure the extent of it. Assuming it is, the NCAA and researches should figure out a way to test different competition and practice schedules to see if it makes a difference. Perhaps a shorter season with a longer offseason is better. Or perhaps the key is to reduce cumulative damage by having longer periods between each game. And if that's the case, the membership should be prepared to take even the radical step of playing football in the spring.
The opinions expressed on this blog are the author's and the author's alone, and are not endorsed by the NCAA or any NCAA member institution or conference. This blog is not a substitute for a compliance office.
About John Infante
The opinions expressed on this blog are the author's and the author's alone, and are not endorsed by the NCAA or any NCAA member institution or conference. This blog is not a substitute for a compliance office. If you're a coach, do not attempt to contact the author looking for a second opinion. If you're a parent, don't attempt to contact the author looking for a first opinion. Compliance professionals are by their nature helpful people generally dedicated to getting to the truth. Coaches should have a bit of faith in their own, and parents should talk to one directly.


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Kristen Schaal Movies
Writer, actress, and comedian
Kristen Schaal
honed her skills working in the New York improve and stand-up scene in the early 2000s. In addition to winning the Best Alternative Comedian Award at the 2006 HBO U.S. Comedy Arts Festival, along with a number of other awards,
began cultivating a career onscreen, appearing on shows like
The Education of Max Bickford
Ugly Betty
, and in movies like
. Her notoriety increased in 2007, when she took on the role of obsessive fan Mel on the comedy series
Flight of the Conchords
would soon find herself part of the Hollywood comedy scene, appearing in numerous movies over the next few years, including
Shrek Forever After
Get Him to the Greek
Toy Story 3
Dinner for Schmucks
, and
Going the Distance
. She appeared in The Muppets in 2011, then was cast to voice one of the main characters in the animated series Bob's Burgers. ~ Cammila Collar, Rovi
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Kate and Leopold
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Filmmaker James Mangold follows his Oscar-winning drama Girl, Interrupted (1999) with this whimsical fantasy. Meg Ryan stars as Kate McKay, a modern female executive in New York City whose drive to succeed in the cutthroat corporate world has left little time for romance. When her genius ex-boyfriend Stuart (Liev Schreiber) opens a portal in time, the experiment transports Leopold (Hugh Jackman) from 1867 to the present day. A charming bachelor and the royal "Third Duke of Albany" in his own time, Leopold is fascinated by the 21st century. As the courtly Leopold and the decidedly liberated Kate tour the town, a mutual attraction develops into something deeper, a relationship that's threatened by Leopold's temporary chronological status. Kate & Leopold (2001) was originally developed by co-screenwriter Steve Rogers as a project for star/producer Sandra Bullock, who had a hit with his film Hope Floats (1998). ~ Karl Williams, Rovi
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Hugh Jackman
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Flight of the Conchords: Season 01
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This rollicking HBO offering chronicled the misadventures of Flight of the Conchords, a two-man "digi-folk" band from New Zealand. It could do nothing less -- starring in the half-hour series was Flight of the Conchords, a genuine two-man digi-folk band from New Zealand consisting of comedians Jemaine Clement and Bret McKenzie, who created the property in concert (no pun intended) with James Bobin. The two protagonists, cleverly named Jemaine and Bret, had come all the way from their mother country to hit it big in New York City. There were only two things keeping them from skyrocketing to stardom: they never seemed to get any decent bookings, and they were bloody awful. Doing rather less than his best to make household names out of Jemaine (the one with the glasses) and Bret (the one with the beard) was their agent-manager Murray (Rhys Darby), whose day job as a cultural aide at the New Zealand Consulate's tourism division gave him plenty of free time -- if not plenty of money -- to arrange such gigs as a retro rock video in which the boys were dressed in ill-fitting cardboard robot suits, and an outdoor concert in Central Park (the wrong Central Park in the wrong city, worse luck). Evidently, Murray was one of only three people in Manhattan who even acknowledged the existence of Flight of the Conchords. The other two were the president -- and only member -- of the band's fan club, an overaged groupie named Mel (Kristen Schaal), who obsessively and lustfully dogged the boys' path, usually chauffeured by her unbelievably unflappable husband; and Dave (Arj Barker), who owned the pawnshop where Jemaine and Bret's instruments were habitually in hock. The series' semi-improvised dialogue and surrealistic storylines were counterpointed by fantasy musical sequences, which gaudily spoofed the music-videos of the past three decades; these vignettes were invariably better than Flight of the Conchords' actual performances, though not by much. Though probably best appreciated by "insiders" in the music business, Flight of the Conchords was broad enough in appeal to tickle the fancy of any comedy fan, while retaining just enough deadpan subtlety to induce quiet chuckles along with the belly laughs. The series debuted June 17, 2007. - Hal Erickson, All Movie Guide
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A meek and lovable milquetoast married to an overbearing, overweight tyrant finds his life turned upside down when he meets the woman of his dreams in this romantic comedy starring Eddie Murphy, Thandie Newton, Cuba Gooding Jr., and Eddie Griffin. His entire life, Norbit (Murphy) has been picked on and put down, and after being bullied into marrying the most obnoxious woman in town (also Murphy) it appears as if that's the way things will remain until the day he dies. Upon meeting the one woman who seems to accept him for who he is, Norbit is instilled with a newfound sense of hope for the future. In order to find true happiness, however, Norbit will first have to gather the courage to stand up to his monstrous spouse once and for all. ~ Jason Buchanan, Rovi
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The Goods: Live Hard, Sell Hard
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A smooth-talking jack-of-all-trades attempts to save a struggling car dealership from certain bankruptcy in this comedy starring Jeremy Piven, directed by Chappelle's Show creator Neal Brennan, and produced by Will Ferrell and Adam McKay's Gary Sanchez Productions. Don Ready (Piven) takes sales seriously; he's always up for a challenge, and he parties as hard as he works. Approached to help an ailing car dealership from falling into the red, Ready recruits a crew of his best men and descends upon the quiet town of Temecula determined to succeed. Before long the dealership is flourishing and Ready's crew are kings of the roost, but what happens when the man who made his mint by hustling cars meets the one woman who isn't charmed by his formidable skills as a salesman. Realizing this may be his one shot at true love, Ready starts working overtime to convince the woman of his dreams that he's the best bargain on the lot. Has the hustler finally found his soul, or is he so locked into his anything-goes lifestyle that there's no looking back? Ving Rhames, Ed Helms, James Brolin, and David Koechner co-star. ~ Jason Buchanan, Rovi
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Flight of the Conchords: Season 02
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In their sophomore season, the guitar-playing Kiwis continue their quest to make it big in the Big Apple. Among the highlights: With Murray (Rhys Darby) preoccupied by another band, Bret (Bret McKenzie) and Jemaine (Jemaine Clement) take advantage of his absence and pen a commercial jingle; in the episode A New Cup, an impulse purchase sets off a tempest in a teacup that inspires the Roxanne spoof "You Don't Have to Be a Prostitute"; Dave (Arj Barker) and other unlikely gangbangers watch Bret's back after he disparages A-list rappers (watch for the 'Chords to bust some rhymes about "Hurt Feelings"); and the band, unable to pay the rent, moves in with Mel (Kristen Schaal) and Doug (David Costabile). Season 2 guest stars include Lucy Lawless, Art Garfunkel, Greg Proops, Jim Gaffigan, Kristen Wiig, and Patton Oswalt. ~ Kathy LeSage, Rovi
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Cirque Du Freak: The Vampire's Assistant
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Based on the popular series of books by Darren Shan, Cirque du Freak: The Vampire's Assistant tells the story of a small-town teen who inadvertently shatters a 200-year-old truce between warring factions of vampires. Sixteen-year-old Darren (Chris Massoglia) is your typical adolescent; he spends most of his time with his best friend, Steve (Josh Hutcherson), earns decent grades, and generally manages to stay out of trouble. But trouble finds Darren when he and Steve make the acquaintance of a vampire named Larten Crepsley (John C. Reilly) while attending a traveling freak show at a local theater. Transformed into a bloodsucker by Crepsley, Darren joins the Cirque Du Freak and quickly ingratiates himself with the unusual cast of characters who populate it, including Madame Truska the Bearded Lady (Salma Hayek) and the traveling sideshow's towering barker (Ken Watanabe). As Darren works to master his newfound powers as a budding member of the supernatural underworld, he becomes a valued pawn between the vampires and their deadlier rivals, the Vampaneze. With tensions between the two sects intensifying, Darren must figure out a means of keeping the coming war from destroying his last vestige of humanity. Patrick Fugit, Orlando Jones, Willem Dafoe, and Jane Krakowski co-star. ~ Jason Buchanan, Rovi
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Josh Hutcherson
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Get Him to the Greek
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An ambitious young record company executive attempts to transport an unpredictable rock star to L.A.'s Greek Theatre in time for his hotly anticipated comeback performance in this spin-off of the comedy hit Forgetting Sarah Marshall. Aaron Green (Jonah Hill) has just landed his dream job in the record industry, and he's eager to prove his worth. His first assignment: travel to London and escort British rock god Aldous Snow (Russell Brand) to the show that will re-ignite his career. Before he departs, Aaron is warned by his boss Sergio Roma (Sean Combs) to never let Aldous out of his sight, and never underestimate his capacity for mayhem. Immensely talented yet deeply tortured, Aldous hit the bottle hard after his popularity began to wane and his girl walked out on him. Aldous is locked in the midst of an existential crisis, and rues the thought of being accompanied across the pond by an insincere sycophant. Though it seems like sex is the only thing Aldous ever thinks about, his thoughts turn to romance when he discovers that gorgeous model/pop singer Jackie Q (Rose Byrne) will be in Los Angeles at the time of his concert, too. Jackie Q is the love of Aldous' life, and he'll do anything and everything to win her heart. With the concert fast approaching and Aaron's fledgling career on the line, the race is on to get Aldous to the Greek, and ensure the big show goes off without a hitch. ~ Jason Buchanan, Rovi
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Russell Brand
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Toy Story 3
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Pixar returns to their first success with Toy Story 3. The movie begins with Andy leaving for college and donating his beloved toys -- including Woody (Tom Hanks) and Buzz (Tim Allen) -- to a daycare. While the crew meets new friends, including Ken (Michael Keaton), they soon grow to hate their new surroundings and plan an escape. The film was directed by Lee Unkrich from a script co-authored by Little Miss Sunshine scribe Michael Arndt. ~ Perry Seibert, Rovi
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Tim Allen
, (
Dinner for Schmucks
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An ambitious executive accepts an invitation from his boss to attend a dinner party where high-powered professionals make fun of unsuspecting dimwits in this remake of Francis Veber's 1998 comedy The Dinner Game. Upwardly mobile executive Tim (Paul Rudd) has just landed his company an extremely wealthy Swiss client when his boss, Lance (Bruce Greenwood), invites him to an exclusive, yet unusually mean-spirited dinner party where each of the high-powered executives brings a guest to make fun of. Recognizing that his long-awaited promotion is finally within reach, Tim begins to have second thoughts about participating in the elaborate charade when his longtime girlfriend, Julie (Stephanie Szostak), the successful curator at a local art gallery, voices intense disdain for the idea. The following day, Tim is looking for a way out of the dinner when fate throws the perfect guest right in front of his luxury car. Barry (Steve Carell) is a sweet but dim-witted IRS agent with an unusual hobby: he creates elaborate dioramas featuring stuffed mice. His latest project is "The Last Supper," and he's just put the finishing touches on a tiny mouse Jesus to set at the center of the table. Tim knows that Barry is his ticket to a big corner office on the seventh floor, but the closer the party looms, the more he realizes that his bumbling new acquaintance isn't just an idiot, but also is a magnet for chaos. ~ Rovi
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Paul Rudd
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Going the Distance
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Drew Barrymore and Justin Long star in this romantic comedy about a long-distance romance that may be worth fighting for. Garrett (Long) is still nursing the wounds from a recent breakup when he meets Erin (Barrymore), an unflinchingly honest girl with a big talent for bar trivia. Hitting it off immediately, the pair spend a romantic summer together in New York City. It was supposed to be a summer fling, but as fall approaches and Erin returns to San Francisco, the spark is still there. Subsequently dividing his days between working and hitting the bars with best friends Box (Jason Sudeikis) and Dan (Charlie Day), Garrett drops everything whenever Erin calls. The more Garrett's phone rings, the more his pals begin to suspect that their drinking buddy is taking the relationship a little too seriously. And they're not the only ones; Erin's sister, Corrine (Christina Applegate), is keen to ensure that her smitten sibling doesn't repeat the mistakes of her past, and she makes no attempts to sugarcoat the fact that she disapproves of the coast-to-coast romance. But the heart wants what the heart wants, and as the texting becomes more intense, both Garrett and Erin start to suspect that their summer fling may just be the real thing. ~ Jason Buchanan, Rovi
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Justin Long
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Valentine's Day
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Gary Marshall's ensemble romantic comedy Valentine's Day follows nearly two dozen people as they find and lose love in all its many forms over the course of the title holiday. The numerous characters include a very busy florist (Ashton Kutcher) and his schoolteacher best friend (Jennifer Garner). She's having an affair with a married doctor (Patrick Dempsey). Meanwhile, a businessman (Bradley Cooper) and a military captain (Julia Roberts) on leave share a long conversation during an international flight. There's also an elderly couple (Hector Elizondo and Shirley MacLaine) who are caring for their elementary school-age grandson, who is pining for a classmate and missing his mother. The huge cast also includes Jamie Foxx as a local TV personality, Topher Grace, Queen Latifah, and Anne Hathaway. ~ Perry Seibert, Rovi
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Julia Roberts
Emma Roberts
, (
Shrek Forever After
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A domesticated Shrek hatches a plan to recapture his mojo and discovers what life in Far Far Away land would have been like had he never existed in this final chapter of the popular animated film series. There used to be a time when the villagers would run in terror at the mere mention of the name Shrek, but these days the big green ogre is married to Princess Fiona and raising triplets. Maintaining your fierce public persona is no simple task when you're juggling infants and changing diapers, so when Shrek realizes that nobody is afraid of him anymore he recruits mischief-maker Rumpelstiltskin to restore his once-mighty roar. Unfortunately for Shrek, that plan hits an unexpected hitch. As a result, the morose monster takes a trip into an alternate-universe Far Far Away land where there is no Shrek, and Rumpelstiltskin reigns. There, Donkey spends his days hauling carts, and a portly Puss in Boots prefers lounging to swashbuckling. Perhaps with a little extra effort, Shrek will be able to regain his status as top ogre in town and still have his happily ever after, too. ~ Jason Buchanan, Rovi
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Eddie Murphy
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When in Rome
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Disillusioned with romance during her whirlwind trip to Rome, an ambitious New Yorker defiantly swipes a few magic coins from a "foolish" wishing fountain, inadvertently igniting the passions of a motley crew of suitors as she's pursued by a handsome reporter with charm to spare. Beth (Kristen Bell) is at a point in her life where love seems like a luxury she just can't afford. Years of waiting for that perfect romance has made Beth bitter, and one day, while vacationing in Rome, she cynically plucks a handful of coins from a local fountain of love. Almost immediately thereafter, Beth finds herself fending off the advances of a diminutive sausage magnate (Danny DeVito), a lanky street magician (Jon Heder), a doting painter (Will Arnett), and a narcissistic male model (Dax Shepard). Meanwhile, a smitten reporter (Josh Duhamel) does his best to convince Beth that true love isn't just a topic of fairy tales and romance novels. ~ Jason Buchanan, Rovi
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Josh Duhamel
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Jim Field Smith's gentle satire Butter stars Jennifer Garner as Laura Pickler, the wife of the longtime winner of a local butter-carving contest. When he decides to bow out of this year's competition, she can't imagine the family not having the title, so she begins to train herself. Her biggest rival turns out to be a young adopted African-American girl named Destiny (Yara Shahidi), who has a natural gift for sculpture. As the competition gets more and more fierce, Laura resorts to drastic measures, convincing an old flame to perform some dirty tricks in order to get the upper hand. Butter screened at the 2011 Toronto International Film Festival. ~ Perry Seibert, Rovi
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Olivia Wilde
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The Muppets
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When an evil oil man discovers black gold beneath Muppet Theater, Kermit recruits a Muppet super-fan and his two best friends to help gather up the gang for a telethon that will save the venue from being razed and replaced with a giant oil pump. Tex Richman (Chris Cooper) never met an oil field he couldn't suck dry. So when Tex discovers a bountiful reservoir right underneath Muppet Theater, he begins drawing up plans to claim the land and start drilling. Little does Tex realize that devoted Muppets fan Walter is currently in Los Angeles with his best friends Gary (Jason Segel) and Mary (Amy Adams), and that he's not about to let one man's greed spoil a good thing for everyone. With Kermit by their side, Walter, Gary, and Mary hatch a plan to put on a big telethon that will help them raise the ten million dollars needed to keep Muppet Theater standing. But rounding up the gang won't be easy, because these days Miss Piggy's got a posh job at Vogue Paris; Fozzie has landed a gig at a Reno casino; Gonzo has become the owner of a successful plumbing company; and Animal is dealing with anger management issues in a Santa Barbara clinic. With the drilling deadline fast drawing near and Tex wringing his hands in anticipation, the gang races to put on the performance of a lifetime and save Muppet Theater from certain destruction. Directed by James Bobin and written by Segel and Nicholas Stoller, The Muppets Movie features cameos by Zach Galifianakis, Billy Crystal, Jack Black, Alan Arkin, and Jean-Claude Van Damme, among others. ~ Jason Buchanan, Rovi
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Amy Adams
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Hawaiian Vacation
Originally released into theaters to accompany Cars 2, the Toy Story short Hawaiian Vacation finds Woody (voice of Tom Hanks), Buzz (voice of Tim Allen), and the rest of Bonnie's new toys planning an unforgettable Hawaiian getaway for their glamorous pals Ken (voice of Michael Keaton) and Barbie (voice of Jodi Benson). When Ken's vacation plans hit an unforeseen snag, his devoted pals hatch a plan to give the well-dressed doll and his adoring girlfriend the ultimate staycation from the comfort of Bonnie's bedroom. ~ Jason Buchanan, Rovi
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30 Rock: Season 06
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Beer Guy: Highland plans 20 brews for 20 years
Highland Brewing is already well into planning for 2014, a year that will mark it's 20th year in business.
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Highland Brewing is already well into planning for 2014, a year that will mark it's 20th year in business.
Answer Man looks into expensive "street furniture" and the fact that a house rarely wins recent Gingerbread House Competitions.
'Now is the winter of our discontent/made glorious summer ...' That's the first line of Shakespeare's Richard III, and while I'm guessing not too many baseball players are up on the writings of the Bard, there are several with Western North Carolina ties that hope some discontentment this offseason leads to a glorious summer of 2014.
Columnist John Boyle peers into his crystal ball to see what's in store for a piece of city-owned property that's been vacant and dilapidated for a decade.
Prime time matchups don't get any bigger than this. The New Orleans Saints (9-2) at the Seattle Seahawks (10-1), who have a franchise best 13-game winning streak at Century Link Field, which has turned into the nastiest road venue in the NFL. But extending that streak will be difficult.
It's been three days since Thanksgiving.
Several weeks ago the Thanksgiving Day matchup between Detroit and Green Bay looked like one of those special, can't miss type of games.
At first glance, it looks like business as usual in Cullowhee for the Western Carolina football season.
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New TNS-BMRB Scottish Referendum poll
TNS BMRB released a new poll on the Scottish independence referendum this morning. I expected several polls to appear in the wake of the publication of the white paper, letting us see if it had any effect on referendum voting intentions.
This alas is not one of them, as annoyingly it was carried out almost wholly before the white paper was published. For the record the figures show very little change from the previous TNS poll in October. The YES vote stands at 26%(+1), the NO vote at 42%(-1), 32% are undecided (for some reason TNS tend to show a much higher level of don't knows compared to other Scottish referendum polls). Full tabs are here.


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3 bedroom detached bungalow to rent BENLLECH
A spacious modern detached bungalow in a popular residential area of Benllech, approximately 10 miles from Bangor. Accommodation consists of Hall; Lounge; Kitchen/Diner; Bathroom/WC with shower and 3 Bedrooms. The property also benefits from LPG Central Heating and Double Glazing throughout. Gar... More details ›
Marketed by Dafydd Hardy, Menai Bridge. Telephone: 01248 343010 Local call rate
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£595 pcm
2 bedroom detached bungalow to rent Benllech, Anglesey, North Wales
A Well maintained fully Furnished 2 Bedroom Detached Bungalow with Sea Views situated on a popular Residential Estate and within easy reach of all village amenities. The property benefits from having Night Storage Heating and is Double Glazed throughout the accommodation briefly comprises; H... More details ›
Marketed by Dafydd Hardy, Menai Bridge. Telephone: 01248 343010 Local call rate


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Spanish chef Dani Garcia is putting in hour after hour of work and sacrifice to achieve his dream of conquering the palates of New Yorkers with Manzanilla Spanish Brasserie.
The eatery, which is at 345 Park Avenue South, brings the dishes of Marbella, in southern Spain, nearly 6,000 kilometers (3,728 miles) to diners in Manhattan.
Garcia, who was born in Marbella in 1975, says he welcomes diners to a "very New York" space that has Andalusian roots adapted to the Big Apple.
"It's a lifeline, it's oxygen, it is many things for me professionally and personally, much more important than it might appear," the famous chef of Calima, a Marbella restaurant awarded two Michelin stars, said in an interview with Efe.
Manzanilla Spanish Brasserie is not a tapas bar like the similarly named establishment in Malaga or a haute cuisine restaurant like Calima, the chef said.
"It's a brasserie, a pretty open concept and very New York, very geared to the city," but without forgetting its roots, Garcia said.
The chef and his mother, Isabel Reinaldo, have just teamed up to publish "En la cocina de mi madre" (Ediciones B), a collection of innovative recipes for preparing traditional and new dishes.
"It is inevitable, your way of cooking is unique and even if I open myself up to new ingredients, in the end you are you, and your kitchen has your personality and your flavor, and, if you can, in 80 percent of the cases, it is a reminder of the kitchen in your home, in your land, of what you have lived all your life," the chef, who trained with Martin Berasategui, said.


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Bee and Wasp Sting (cont.)Medical Author:
Melissa Conrad Stöppler, MD
Melissa Conrad Stöppler, MDMelissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology. Medical Editor:
William C. Shiel Jr., MD, FACP, FACR
William C. Shiel Jr., MD, FACP, FACRDr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology. In this Article
What are causes of bee and wasp stings?Most stings arise because an insect perceives a threat to their colony. Bees and wasps commonly sting because an intruder has neared the hive or nest. Loud noises (such as lawn mowers), bright or dark colors, and certain perfumes or perfumed body products may also encourage stings. Some types of insect venom contain pheromones, which attract other members of the colony and induce them to sting.
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When bees or wasps sting an individual, they inject venom under the skin of their victim.
Bee and wasp venoms vary according to species but typically contain toxic components as well as antigens that stimulate an immune response. What are the symptoms of a bee or wasp sting?Insect stings may produce four types of reactions, each with characteristic symptoms as below:
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Bee and Wasp Sting - Describe Your Experience
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San Francisco Journal
Tony sipped on absinthe and sampled sushi in the City by the Bay. Check out his San Francisco Photo Journal.
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Tag Archives: laura fryer
Thu, Oct 18, 2012 | 14:19 BST
Epic Games hire Laura Fryer as general manager of Seattle Studio
Epic Games has announced the hiring of Laura Fryer as general manager of its new Seattle studio. This particular branch is currently working on the company's Unreal Engine 4 technology. Fryer arrives having enjoyed more than 17 years of industry experience.
Thu, Jul 21, 2011 | 02:07 BST
Warner Bros. boss calls out "slash and burn" management
Warner Bros. Games general manager and vice president Laura Fryer has criticised the practice of hiring, burning out, and then firing development staff.
Tue, May 10, 2011 | 11:20 BST
Warner: New Monolith title to be shown soon
Warner Bros. Seattle head Laura Fryer has said that the new title from F.E.A.R. developer Monolith will be unveiled soon.
Fri, Feb 13, 2009 | 15:48 GMT
Gears of War 2 lead jumps to Warner
Laura Fryer, Gears of War 2′s executive producer, has jumped ship to Warner Bros.
She will now head up FEAR 2's Monolith Productions, as well as Snowblind Studios, as the general manager of Warner's Seattle operation.
"Laura's extensive career demonstrates her great understanding of the process and her ability to innovatively grow our development studios," said Samantha Ryan, development boss at Warner Bros.
"Utilizing her expertise to direct our Seattle studios in several key areas, we are looking forward to developing quality games under her leadership in the most efficient ways."
Press release here.


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- Total number of rooms - 52
- Number of floors - 2
- Number of buildings/towers - 1
- Swimming pool - outdoor seasonal
- Air-conditioned public areas
- Free Wi-Fi
- Microwave in lobby
- Free parking
- Self parking
Situated in the business district, this hotel is close to Petaluma Village Premium Outlets and Santa Rosa Junior College-Petaluma Campus. Area attractions also include Phoenix Theater and Petaluma Historical Museum.
Americas Best Value Inn & Suites provides complimentary wireless Internet access, free parking, air conditioning in public areas, and self parking.
Televisions come with premium satellite channels. Guestrooms also feature complimentary wireless Internet access, air conditioning, and direct-dial phones.
The preferred airport for Americas Best Value Inn & Suites is San Francisco, CA (SFO-San Francisco Intl.) - 77.4 km / 48.1 mi.
Distances are calculated in a straight line from the property's location to the point of interest or airport and may not reflect actual travel distance.
Distances are displayed to the nearest 0.1 mile and kilometre.


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(NEWSER) – Looks like George Zimmerman has taken time out from visiting gun factories and speeding in Texas to take care of more legal business: He plans to ask the state of Florida to reimburse him for up to $300,000 in legal expenses, his lawyer tells the Orlando Sentinel. Because he was acquitted, a Florida statute requires the state to pay his costs for things like expert witnesses and travel, and he plans to file a motion soon, lawyer Mark O'Mara says.
Read more from Newser.com


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In Brief
- Plastic debris in the sea does not get digested by microbes, but it does "photodegrade": ultraviolet light and heat make it brittle and prone to cracking.
- Scientists fear tiny bits called microplastics could harm small creatures at the base of the food chain, such as by blocking their digestive tracts. The plastics may also concentrate toxic substances.
- In these ways the microplastics might be bad news for the rest of the food chain--including us.
By now even schoolchildren know that the plastics we discard every year in the millions of tons persist in the environment for hundreds of years. And we have all heard of the horrors caused by such debris in the sea: fur seals entangled by nylon nets, sea otters choking on polyethylene six-pack rings, and plastic bags or toys stuck in the guts of sea turtles. This photograph, showing plastic fragments collected in just an hour at a cove near Gloucester, Mass., hints at a lesser-known but equally disturbing story: much smaller bits of plastic that are accumulating in oceans all over the world can potentially harm marine life and possibly even human health.
Although plastic does not get digested by microbes, as food and paper are, it does slowly "photodegrade": ultraviolet light and heat from the sun increase its brittleness, causing it to weaken, crack and break up into smaller and smaller fragments. Indeed, a handful of sand or cup of seawater from nearly anywhere in the world will probably be peppered with microplastics—pieces that are tinier than a small pea and often invisible. Scientists fear the possible effects of this plastic confetti on zooplankton and other creatures at the base of the marine food web, which get consumed by larger organisms—turtles, fish, birds—and, ultimately, by us.
This article was originally published with the title Plastic Surf.
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1988-91 3/4 Ton Suburban Straight Axle 4WD Chevy, GMC Suspension Lift Kits
Suspension lift kits for your straight axle 4WD Chevy or GMC Suburban are available in many different sizes to suit your needs. The suspension lift kit manufacturers found here can give your vehicle the look you want allowing for a larger tire and wheel combination plus increased ground clearance.
Tuff Country offers 2 types of spring packs. Both types of Tuff Country leaf springs are snub rolled, Teflon padded and pre-set for the ultimate combination of ride quality and durability. The Tuff Country EZ-Ride springs provide a more compliant ride with a slightly lower load capacity than the Heavy Duty springs. If your Chevy or GMC has a winch or heavy bumper, the Heavy Duty spring with its higher load capacity would be a better choice to maintain the ride height. Backed by the Tuff Country Limited Lifetime Warranty.
Vehicle | Drive | Price | Item # |


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Bloggers mixed on jail time for phoning while driving
We know better, but we all do it anyway. We're negotiating traffic, the cell phone rings and it's that call we've been waiting for...the one that has to be answered. We take it, knowing full well we're putting ourselves, our passengers and others on the road at risk.
In Britain, that offense might just land you in jail for two years, according to an article on the Evening Standard's Web site. The story, which has bloggers typing away, says penalties for "dangerous driving" are being stiffened because of widespread public concern about … Read more


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If you were a member of gantthead.com, you are already registered here--just use the same username and password to login and enjoy the same valuable resources and connections you have come to rely on.
Rally - Gartner Names Rally a Magic Quadrant Leader in Application Development Life Cycle Management
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Efficiency: November 2011 Archives
When Dennis Meissner of the Minnesota Historical Society spoke to some 150 attendees at the Good Practices for Great Outcomes: Cataloging Efficiencies that Make a Difference event hosted with DePaul University Libraries he did so as a relative outsider: as an archivist who focuses on making archival collections available, speaking to a room focused primarily on cataloging traditionally published materials.
The solutions Dennis invokes apply to both communities:
- User access is paramount. We need to be audience driven.
- Risk is unavoidable. We need to determine the minimal acceptable level of cataloging and make that the benchmark.
In his presentation, Dennis used these pictures. We need to move:
We need to go from artisan-level cataloging to production level cataloging. Dennis refers to this as meaningful scale. In Dennis' archival world, where he has many items that are part of distinct collections, a key aspect to his strategy is in focusing on the collection rather than the individual items. He bundles multiple items into a collection (in practice, often a single PDF) and focuses on metadata at the collection-level. His goal is to use his minimal acceptable benchmarks to push the material into user discovery as quickly as possible.
While the possibilities for cataloging and processing archival materials are different than for traditional library materials, his principle of using minimal acceptable benchmarks to push the material into user discovery as quickly as possible can be applied. For instance, we can quickly catalog large sets of electronic content by using sets of cataloging records (such as those available via WorldCat Collection Sets). And we can employ minimum-level benchmarks to traditional copy cataloging, by abandoning most or all local practices to edit or improve a single copy catalog record in the local system, and instead, rely on services such as Bibliographic Record Notification and WorldCat Cataloging Partners to catalog at a collection-scale and push the records into discovery at quickly as possible.
More Product, Less Process. It's catchy, and can be applied to any technical services workflow to achieve cataloging efficiencies that make a difference.


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Let me know! Send me a PM, post in here, or email email@example.com
I am looking for 1-2 girls. Supplements would have to be PES supplements only, provided by me.
Not many girls on this board, so ask your wife/girlfriend/girl friend
Video log would need to contain 1 video for:
Week 1
Week 2
Week 3
Week 4
Conclusion and Final Review
Videos can be emailed to PES and then will be hosted on PES Youtube channel.
So who wants to become a movie star?
Thanks to the guys who quickly took advantage of this opportunity!


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NEW YORK - MARCH 10: (L-R) Actor Colin Hanks, John Malkovich and The Amazing Kreskin attend The Cinema Society and Brooks Brothers screening of "The Great Buck Howard" at the Tribeca Grand Screening Room on March 10, 2009 in New York City. (Photo by Stephen Lovekin/Getty Images) *** Local Caption *** Tom Hanks;John Malkovich;The Amazing Kreskin
UPLOADED ON 2009-03-10 21:10:15 PHOTO BY Getty Images
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As a snowboarder, I arrived at Deer Valley—a skiers-only resort—a skeptic. That suspicion began to melt away as soon as I was greeted by the ubiquitous, and very friendly, ski valets.
Wide, tree-lined pathways; brick and stone buildings covered in ivy; playing fields; a clock tower—The American Club Resort in Kohler, Wisconsin, feels so much like a college campus, I wished I had packed a letter sweater.
This past summer, I fled the steamy streets of New York City for Primland, a luxurious eco-friendly resort in the heart of Virginia's moonshine country. Primland sits on 12,000 acres of hunting land pocketed between the headwater of the Dan River and the sloping Blue Ridge Mountains.
The standards of hospitality are high in the Napa Valley, from the quality of the wine to chefs like The French Laundry's Thomas Keller and Meadowood's Christopher Kostow, who use incomparable local ingredients to create some of the world's most refined and beautiful food. Hotels do their best to follow suit and up in Calistoga, where the hot springs bubble, one of my favorite places to stay is Solage, a low-key resort and spa with bungalow-type rooms spread out across a sunny patch of Valley floor. Keep reading »
When "La Grande Dame de la Rue Sherbrooke" first opened its doors on New Year's Eve in 1912, it was the first hotel in North America to bear the name Ritz-Carlton, an undisputed jewel of a first class residential hotel, and the epitome of style and elegance. Heads of state, movie stars and royals stayed here. It was a favorite of President Taft's. Liz Taylor and Richard Burton married in the royal suite in 1964. Keep reading »
As we walked through the immaculately manicured flower and herb gardens of Beach Plum Farm in Cape May, Curtis Bashaw explained that his southern New Jersey town was originally a whaling village, but became America's first resort destination for wealthy turn of the century elite from Washington D.C., Philadelphia and New York. By the 1970's, when teenage Bashaw arrived with his grandfather, a traveling preacher, the town had become a rundown shadow of its former glory. Keep reading »
This historic hotel features the imperial cuisine of Hue, Vietnam: intricate, tapas-style dishes like banh beo, delicate, steamed glutinous rice cakes topped with shrimp and crispy pork rinds; miniature spring rolls; delicately fried prawns, and more.
The Gladstone, a boutique hotel that debuted in Toronto's trendy West Queen West neighborhood in 2006, has a history that spans centuries. Originally built in 1889 as an upscale inn, it soon became known as a preferred spot for visiting artists and vaudeville performers. Over time, it fell into serious disrepair, and remained that way until 2000 when it was bought and renovated by Christina Zeidler. Keep reading »
Montréal is an exceptional city for walking. With several streets closed off to cars, broad pedestrian malls, and miles of underground corridors to explore, it's a fantastic city to discover on foot. But after a long afternoon of shuffling over concrete and cobblestone, through museum and park and avenue, my feet desperately needed a rest. Keep reading »
When it comes to hotels, there's luxury and then there's luxury.
There are properties that gift you with a fruit basket upon arrival, then there are properties that lay out a platter of bite-sized miang kum, savory snacks wrapped in fresh betel leaves. There are resorts that boast of Olympic-sized swimming pools, then there are resorts that neatly outfit their individual suites with private pools overlooking the ocean. There are concierges who can suggest activities for you, and then there are the hotels that arrange for baby elephants to visit their beachside patio bar at sunset. Guess which category Krabi's Phulay Bay falls under? Keep reading » -
Sunny Jin, the executive chef of the restaurant JORY at the Allison Inn and Spa, is excited about radishes. In the new farm-to-table zeitgeist, this, in and of itself, is not at all unusual, and it's even less unusual when the restaurant in question is a stone's throw from Portland, Oregon. What is unusual, and what comes to define my overall experience of the Allison, is the fact that the radishes are from a local high school student's 4-H project. "Sure, I could get them from somewhere else," he says, "but how cool is it to get them from this kid who's just pumped about growing them for us?" Keep reading »
Though I live in New York City, I am constantly discovering new things about my town, and my recent stay-cation at the James Hotel was similarly full of surprises. I arrived at the Soho property with my boyfriend in tow and we were directed to a glass elevator that whisked us up to Sky Lobby, a glass encased check in area and designer lounge. We left our bags with the bellman and headed straight to the comfortable sitting area overlooking the urban sculpture garden and miniature croquet lawn. We flipped through the art books scattered throughout the space and helped ourselves to the complimentary nibbles and sips, which change throughout the day. In the mornings, there is La Colombe Coffee and delicious, bite-sized scones from David Burke Kitchen; during the day, there is lemon water and fruit; and in the evenings, complimentary local wine from Long Island's North Fork is available, along with cheese, fruit and crackers. After 8:00pm, fresh-baked cookies appear. Read more »
Since the 1980s, the neighborhood in Columbus known as the short north—14 blocks in downtown Columbus—has been and continues to be a bustling arts district, home to 40 art galleries and dozens of great restaurants. The neighborhood's biggest gallery—and the only one open 24/7—also happens to be a hotel. Read more »
The grand Langham Huntington Hotel sits at the base of the San Gabriel Mountains, tucked away from L.A.'s freeways in an oasis of green. Originally opened in 1907, the landmark building and its 23-acre grounds were once a winter resort for wealthy escapees from the cold of the East and Midwest. More than a century later, the hotel still radiates classic elegance, but with an easy-going feel. Read the full review »
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I never really thought about the trucking industry getting competition from rail. It makes all the sense in the world, just something that never entered this head. Kudos to the trucking companies for using IP technology to deliver a better product. Anything that helps get the item to it's destination quicker is key.
Fewer want to become truckers, Alison.
At issue is they don't want to be away from home.
To compensate, many truck cos. are starting to run shorter "tag team" routes--where a driver drives 250 miles one way (and back) in a day. Then, another "relay" driver does the aame thing as the route continues.
Maybe the driver shortage will be filled by autonomous vehicles... Robots don't feel boredom and don't need bathroom breaks.
Yes, I've heard that, too, Mary. And we know that even hard-hit USPS' package delivery service is doing well in an era of online ordering. With the driver shortage, is it that truck companies need to hire more drivers or that fewer people want to become truckers?
I guess as long as the rewards far outweigh the risks then it might not only be a costs-leading implementation.
There are obviously some problems in this area.
Almost every trucking company I talk with says that they can't find enough drivers.
I would suspect trucking firms' use of tech will certainly help their bottom line in the near and far term. I wonder though how it affects the paychecks of the drivers.
With the second by second monitoring possible, and the ability to compare driver to driver rather easily, it would be easy to put some stiff demands on drivers to improve the company bottom line.
I've heard from a few drivers who are now complaining about the low actual wages earned considering the 'down' time encountered in loading and unloading, and waiting time. What seems like a good per mile earning is eaten away by the time not driving.
Now, if tech can improve the wait times, maybe drivers will benefit, but it doesn't seem to be helping from the drivers who are speaking out.
Most definitely.
Many companies are using trucking to help them arrive at their sustainability goals.
Could this lead to more cost savings if the proposed carbon sale comes into effect? Ceratinly there has tobe greaterrewards other than just rewarding safe drivers.


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Fresh from the Image Gallery.
Add a commentThis was an idea sent to me from a friend, Eric Andrews. Be sure to check out the page, there's a lot of really great posts there.
Add a commentFresh from the Image Gallery.
H/t to YoungCons for the original idea.
Add a commentMaybe then news like this will seep into the minds of all those liberals idiots low-information voters out there.
Apple made business decisions that saved it billions in taxes. What was so illegal about doing such a thing? Nothing, absolutely nothing, but don't tell that to the Democrats...
Add a commentFresh from the Image Gallery.
Add a commentI wish I could say this post was unprovoked, but one Democrat wasted no time politicizing the Oklahoma tornado tragedy. They're forcing the point...shamelessly.
I wish we could say this type of nonsense couldn't have been expected from the left, but that wouldn't be true.
Someone should start a countdown for when Chris Matthews thanks mother nature for a deadly and destructive storm...it wouldn't be the first time he did it.
Add a commentNormally the title of this post is "Conservative Image of the Day." Not today. This says it all for all affected by the devastating (to put it very mildly) tornado in Oklahoma.
Here is a list of organizations taking donations (h/t NakedDC)
Fresh from the Image Gallery. If you don't have money you can definitely give this...
Add a commentLiberals think crap like this is leadership, go figure.
Add a commentI can't say I came up with this totally on my own, it was largely inspired by this piece from iOwnTheWorld.
Add a commentFresh from the Image Gallery.
Add a commentCould you imagine if this were the scene? (yes we can!)
This whole thing goes right in line with this post I did about the study showing strong men tend to be conservative.
Add a commentBoy, opening an umbrella is only supposed to be bad luck when it's done inside!
So, I saw this post with this image at Free Republic. After I was done laughing my butt off I decided to take it to another level.
I should consider adding this to my Liberal Supervillains gallery.
Add a commentBecause he's in over his head.....
Get it?
Seriously though...
Lonely Conservative has the video our fearless (except for rain) emperor calling the Marines in to be his hand-maidens posted here.
Add a commentFresh from the Image Gallery.
Add a commentIn fairness to people weary of the current GOP leadership Mitch McConnell probably did NOT come up with this on his own.
Add a commentTrue story, see more about it here.
Add a commentFresh from the Image Gallery.
Add a comment


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Health Sciences
College of Professional Studies
Location: Welch Hall
Phone: 1- 800-344-5484
Fax: 310-516-3542
For more information related to the College, please contact Dean's Office : 310-243 -2046
Radiologic Technology Option
Main Page l Curriculum l Admission l Program Description l FAQ l Faculty
The Radiologic Technology Option is designed to accommodate the entering undergraduate or transfer student. The Program is offered in cooperation with the Harbor-UCLA Medical Center School of Radiologic Technology, which is currently accredited by the Joint Review Committee on Education of Radiologic Technologists and approved by the state of California Department of Education for radiologic technology training. Upon completion of the program, students will be qualified to sit for the certification examinations given by the American registry of Radiologic Technologists and the Certification Board of the California Department of Health Services. CRT-BSHS Degree Track applicants must be currently certified as radiologic technologists in California (C.R.T.) to be admitted to the degree completion track for radiologic technologists.
Radiologic Technology Brochure - NEW
For More Information Please Contact
College of Health & Human Services
California State University, Dominguez Hills
1000 East Victoria St., Welch Hall C-300
Carson, CA 90747
CPS Student Services Center (800) 344-5484 or (310) 243-2120
Health Science Program Office (310) 243-3748
Harbor-UCLA Medical Center, School of Radiologic Technology (310) 222-2825