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DEPARTMENT OF HEALTH AND HUMAN SERVICESNATIONAL INSTITUTES OF HEALTHNational Institute of Diabetes and Digestive and Kidney DiseasesFY 2013 Budget Print Version (PDF 465 KB, 28 pages) Organization Chart Appropriation Language Amounts Available for Obligation Budget Mechanism Table Budget Mechanism Table – Type 1 DiabetesSpecial Statutory Authority Funding Only Major Changes in Budget Request Summary of Changes Budget Graphs Budget Authority by Activity Authorizing Legislation Appropriations History Justification of Budget Request Budget Authority by Object Class Salaries and Expenses Detail of Full-Time Equivalent Employment (FTE) Detail of Positions NATIONAL INSTITUTES OF HEALTHNational Institute of Diabetes and Digestive and Kidney Diseases For carrying out section 301 and title IV of the PHS Act with respect to diabetes and digestive and kidney diseases, [$1,800,447,000] $1,792,107,000. (Department of Health and Human Services Appropriations Act, 2012.) Amounts Available for Obligation 1/(Dollars in thousands) Source of Funding FY 2011 Actual FY 2012 Enacted FY 2013 PB Appropriation 1,808,100 1,800,447 1,792,107 Type 1 Diabetes 2/ 150,000 150,000 150,000 Rescission -15,876 -3,403 0 Subtotal, adjusted appropriation 1,942,224 1,947,044 1,942,107 Real transfer under Secretary's transfer authority 0 -512 0 Comparative Transfers for NCATS reorganization 0 0 0 Comparative Transfers to NCATS for Therapeutics and Rare and Neglected Diseases (TRND) -1,476 0 0 Comparative Transfers to NLM for NCBI and Public Access -1,538 -1,627 0 Subtotal, adjusted budget authority 1,939,210 1,944,905 1,942,107 Unobligated balance lapsing -69 0 0 Total obligations 1,939,141 1,944,905 1,942,107
DEPARTMENT OF HEALTH AND HUMAN SERVICESNATIONAL INSTITUTES OF HEALTHNational Institute of Diabetes and Digestive and Kidney DiseasesFY 2013 Budget
Print Version (PDF 465 KB, 28 pages)
NATIONAL INSTITUTES OF HEALTHNational Institute of Diabetes and Digestive and Kidney Diseases
For carrying out section 301 and title IV of the PHS Act with respect to diabetes and digestive and kidney diseases, [$1,800,447,000] $1,792,107,000. (Department of Health and Human Services Appropriations Act, 2012.)
1/ Excludes the following amounts for reimbursable activities carried out by this account: FY 2011 - $3,982 FY 2012 - $6,000 FY 2013 - $6,000 2/ Type 1 Diabetes Special Statutory Authority in Accordance with P.L. 107-360, P.L. 110-275, and P.L. 111-309.
1/ All items in italics are "non-adds"
Major changes by budget mechanism and/or budget activity detail are briefly described below. Note that there may be overlap between budget mechanism and activity detail and these highlights will not sum to the total change for the FY 2013 budget request for NIDDK, which is $2.798 million less than the FY 2012 level, for a total of $1,942.107 million.
Research Project Grants (RPGs; -$14.405 million; total $1,293.302 million): NIDDK will continue to support competing RPGs—693 awards in FY 2013, an increase of 43 from FY 2012. About 2,096 noncompeting RPGs, totaling $874.0 million will also be made in FY 2013. NIH budget policy for RPGs in FY 2013 discontinues inflationary allowances and reduces the average cost of noncompeting and competing RPGs by one percent below the FY 2012 level.
CER Study Toward Establishing Personalized Therapy for Type 2 Diabetes (+$23.0 million; total $23.0 million): A cooperative agreement will support a new, multicenter study of the comparative effectiveness of five common drugs used for therapy of type 2 diabetes.
Causes and Consequences of Cystic-Fibrosis Related Diabetes (+1.5million; total $1.5 million): This new initiative will support studies of the causes and progression of CFRD in humans and animal models, and studies to understand the increased morbidity in patients with CFRD.
Vitamin D for Type 2 Diabetes (D2D Trial) (+5.0 million; total $5.0 million): A cooperative agreement would support a new, multicenter study to test whether vitamin D can prevent or delay progression to type 2 diabetes in adults at high risk of developing the disease.
Drug-Induced Liver Injury Network (DILIN) (-3.25 million; total $0 million): This nationwide study to collect and analyze cases of severe liver injury caused by prescription drugs, over-the-counter drugs, and alternative medicines, is ending in FY 2013 as scheduled.
Studies of Drug-Induced Liver Injury (+3.25 million; total $3.25 million): A new research consortium will be created to study drug-induced liver injury.
Stimulating-Hematology Investigation: New Endeavors (SHINE) (+1.0 million; total $2.0 million): This initiative will continue to support investigator-initiated research project grants in areas of basic and translational hematology research.
Advancing Translational and Clinical Research in Primary Glomerular Disease (+4.0 million; total $4.0 million): This new initiative will support research to identify and test agents that treat or reduce progression of primary (non-diabetic) glomerulopathies.
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) (+2.7 million; total $4.0 million): This new initiative will support a cooperative research network to improve measurement of symptoms in both men and women to advance clinical studies.
1/ .Includes FTEs which are reimbursed from the NIH Common Fund.
2/ Includes Real Transfers and Comparable Adjustments as detailed in the "Amounts Available for Obligation" table.
1/ Includes Type 1 Diabetes Special Statutory Authority Funds.
Authorizing Legislation: Section 301 and title IV of the Public Health Service Act, as amended.
Program funds are allocated as follows: Competitive Grants/Cooperative Agreements; Contracts; Direct Federal/Intramural and Other.
The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to support and conduct research to combat diabetes and other endocrine and metabolic diseases, liver and other digestive diseases, nutritional disorders, obesity, and kidney, urologic, and hematologic diseases. These diseases are chronic, common, costly, and consequential for patients, their families, and our Nation. Diabetes afflicts an estimated 25.8 million people in the U.S., greatly increasing the risk for many serious complications, such as heart disease and kidney failure.[1] Estimates of chronic kidney disease (CKD) show that more than 23 million Americans are affected, and over 550,000 have irreversible kidney failure.[2] Many urologic diseases are also highly prevalent.[3] Digestive diseases account for an estimated 104.7 million visits to ambulatory care centers and 13.5 million hospitalizations per year.[4] Obesity affects approximately one-third of U.S. adults and about 17 percent of children and adolescents.[5] Obesity is a strong risk factor for type 2 diabetes, nonalcoholic steatohepatitis (NASH), and many other diseases. Cystic fibrosis and other genetic diseases within NIDDK's purview are less widespread, but still devastating in their impacts. Building on emerging opportunities from past research investments, NIDDK will continue to pursue basic, clinical, and translational research; research training and career development; and health information dissemination, with continued focus on preserving balance in its investigator-initiated research portfolio.
Support of NIH Director's Themes: Overall Theme: Extraordinary Scientific OpportunitiesThe enormous progress made in understanding and treating chronic diseases now enables us to think boldly and beyond sustained treatment. We are beginning to identify points in the natural history of diseases when efforts to arrest and reverse progression are likely to succeed. For example, NIDDK's Diabetes Prevention Program and its follow-up study showed that type 2 diabetes can be prevented or delayed in high-risk individuals by the oral diabetes drug metformin or lifestyle intervention, and promising pilot studies suggest that translating the lifestyle intervention to lower cost group settings is effective. Already these results are being implemented in YMCAs in many states. An ongoing trial of lifestyle intervention to prevent complications of type 2 diabetes has shown improved control of glucose, blood pressure, and lipids with less use of medications.[6] Research revealed that people with CKD who have elevated levels of a novel biomarker, FGF-23, are at higher risk for kidney failure, cardiovascular disease, and death.[7] Studies showed improvements in aspects of adult and pediatric NASH in response to 2-year therapy with vitamin E.[8] These findings all support identifying windows of opportunity to develop new strategies and discover novel therapeutic targets. By stabilizing and reversing the disease process, we could defer or eliminate the enormous personal and economic costs associated with disease complications. Moreover, we could achieve better medical management of chronic disease until patients could benefit from emerging advances in pharmacology, regenerative medicine, genetics, and other fields. Such efforts complement NIDDK's existing research programs aimed at primary prevention and optimal treatment of these diseases.
Diabetes, Endocrinology, and Metabolic Diseases: The goals of this program are to increase understanding of diabetes and other endocrine and metabolic disorders and to develop and test prevention and treatment strategies. This program supports basic, clinical, and translational research, as well as research training, in the areas of type 1 and type 2 diabetes, cystic fibrosis, obesity, energy balance, and endocrinology. Knowledge from this research is communicated to patients, health professionals, and the public through the National Diabetes Information Clearinghouse and the National Diabetes Education Program. In 2011, NIDDK completed the first major trial of type 2 diabetes management in children and adolescents, a newly emerging problem, and demonstrated that intensive glucose control in people with type 1 diabetes can reduce rates of chronic kidney disease and end-stage renal disease by 50 percent 22 years later.[17] Trials investigating bariatric surgery as treatment for diabetes continued, as well as experimental studies of bariatric surgery in animals. NIDDK supported planning grants for a comparative effectiveness clinical trial testing different medications, in combination with the oral diabetes drug metformin, for type 2 diabetes treatment, and for a clinical trial testing vitamin D in prevention of type 2 diabetes based on a promising pilot study.[18] New initiatives are fostering research toward preserving function of insulin-producing beta cells early in the course of type 2 diabetes, and a new consortium was launched to study approaches to prevent gestational diabetes. The Beta Cell Biology Consortium identified a potential new strategy to induce beta cell regeneration to replace lost beta cells and reverse aging-associated decline in beta cell growth.[19] In addition, NIDDK continues efforts to understand and ameliorate disparities in diabetes with research to identify gene regions conferring type 2 diabetes risk in multiple ethnic groups, translational research to bring scientific discoveries to all who can benefit, and a clinical trial of type 2 diabetes management including minority youth and adolescents.
Budget Policy: The FY 2013 President's Budget request for this program is $634.121 million, a decrease of $1.147 million or 0.18 percent below the FY 2012 Enacted level. With FY 2013 resources, NIDDK will continue major diabetes clinical trials and encourage and support development of major new investigator-initiated clinical studies. FY 2013 funds will also support research capitalizing on new opportunities to identify diabetes risk genes in minority populations, to advance progress toward developing new therapeutic approaches, and to support comparative effectiveness research. New research efforts to study the causes and consequences of cystic fibrosis related-diabetes will be supported. NIDDK will also continue to fund translational research in FY 2013 and support health information dissemination activities to bring scientific discoveries in diabetes and obesity to real-world medical practice and other community settings. In FY 2013, NIDDK will continue an initiative encouraging collaborative, multidisciplinary research teams to work on complex biomedical problems in diabetes, endocrinology, and metabolic diseases. NIDDK will also continue funding for research centers to advance research relevant to diabetes and to cystic fibrosis and other genetic metabolic diseases. NIDDK plans for FY 2013 include capitalizing on new findings relevant to brown fat and gestational diabetes and pursuing other efforts as part of an overall balanced research program.
The ambitious, long-term TEDDY study aims to discover the infectious agents, dietary factors, or other environmental conditions that trigger type 1 diabetes in genetically susceptible individuals. Investigators screened over 425,000 newborns to identify infants with an increased risk of type 1 diabetes. Over 8,000 high-risk infants are now being followed from birth through 15 years of age. For a decade and a half, investigators will regularly collect information on the child's diet, illnesses, vaccinations, and psychosocial stresses; biological samples, including blood, stool, and toenail clippings, will be collected and made available to researchers worldwide through the NIDDK Central Repositories. In addition, TEDDY children are frequently tested for evidence of the autoimmune process that characterizes type 1 diabetes, enabling researchers to study the very early stages in the development of the disease. Investigators are now beginning pilot studies to identify environmental triggers. Children enrolled in the study are developing autoimmunity and type 1 diabetes at the predicted rates, indicating that those at risk can be accurately identified and that the study is on track to make a major contribution. The substantial investment in TEDDY can reap major rewards and revolutionize the ability to prevent type 1 diabetes. Identification of a dietary or infectious cause of type 1 diabetes could have an enormously positive impact on public health through a diet change or vaccine for disease prevention. Because celiac disease and type 1 diabetes share some genetic susceptibility factors, newborns studied in TEDDY are also at high risk for celiac disease and investigators are studying the development of this disease as well.
Digestive Diseases and Nutrition: The goals of this program are to increase understanding of digestive diseases, nutrition, and obesity, and to develop and test strategies for disease prevention and treatment. This program supports basic, clinical, and translational research, as well as research training, encompassing fundamental studies of the digestive system; disease-targeted research involving the esophagus, stomach, small intestine, large intestine and anorectum, liver and biliary system, and pancreas; studies relevant to nutrition; and research on obesity. Insights gleaned from scientific efforts are communicated to patients, health professionals, and the public through NIDDK's National Digestive Diseases Information Clearinghouse and Weight-control Information Network. NIDDK supports the Hepatitis B Research Network, which will test treatments in at-risk populations, such as Asian Americans and Pacific Islanders. CHILDREN, a network conducting studies on severe forms of childhood liver injury, will include a new focus on liver disease associated with cystic fibrosis. NIDDK supports A2ALL, a study of risk and benefits associated with adult-to-adult living donor transplantation. NIDDK will continue CORI, a clinical outcomes research initiative and the largest national database on gastrointestinal endoscopy. The Nonalcoholic Steatohepatitis Clinical Research Network will continue to complete clinical trials in adults and children and collection of biospecimens and data. NIDDK supports the Gastrointestinal Stem Cell Consortium to improve understanding of intestinal biology and function, and aid therapeutic development through research on gastrointestinal progenitor cells. Studies by the Acute Liver Failure Study Group were key to developing new regulations regarding acetaminophen and showing the benefits of N-acetylcysteine for treating acute liver failure due to other causes.[20] Support of Look AHEAD, a major long-term study that aims to determine whether intensive lifestyle measures involving diet and exercise improve morbidity and mortality from cardiovascular diseases in people with diabetes, will continue.
Budget Policy: The FY 2013 President's Budget request for this program is $494.924 million, a decrease of $0.895 million or 0.18 percent below the FY 2012 Enacted level. In FY 2013, NIDDK will continue major clinical research networks to help understand and treat liver diseases, including hepatitis B and nonalcoholic steatohepatitis. Among its obesity-related efforts in FY 2013, NIDDK will support major ongoing observational studies to assess the health risks and benefits of weight-loss surgery in extremely obese adults and adolescents, as well as an ongoing trial evaluating the long-term health effects of weight loss in obese adults with type 2 diabetes (Look AHEAD). NIDDK will also use FY 2013 funds to support Digestive Diseases Research Core Centers, and to sustain a consortium that is conducting cutting-edge genetic research on inflammatory bowel diseases. Research on intestinal stem cells that can benefit a variety of digestive diseases will continue in FY 2013, along with other efforts as part of an overall balanced research program.
Numerous observational studies have linked overweight/obesity, and/or excessive gestational weight gain during pregnancy to short-term and long-term adverse health consequences in both mothers and offspring, but additional research is needed to identify effective interventions that will improve weight, glucose, and other pregnancy-related outcomes in mothers and determine whether these interventions affect obesity and metabolic abnormalities in the offspring. In FY 2013, NIDDK will continue clinical studies testing behavioral/lifestyle interventions in overweight and obese pregnant women. These studies include testing a novel lifestyle intervention given to obese, socioeconomically disadvantaged African American women through an existing national home visiting program; a personalized gestational weight management program for overweight and obese women delivered in person or remotely via a Smartphone; and an intensive lifestyle intervention provided through weekly counseling sessions during pregnancy and group counseling after delivery. All studies include follow up post-partum to determine weight and/or metabolic outcomes in both mothers and offspring. A Research Coordinating Unit facilitates collaboration, coordination, and exchange of scientific information among the investigators. Results from these studies could lead to an effective lifestyle intervention for overweight/obese women during pregnancy, reducing post-partum weight retention; incidence of gestational diabetes and subsequent development of type 2 diabetes in the mother; and the risk for obesity, metabolic abnormalities, and adverse cardiovascular outcomes in both mother and offspring.
Kidney, Urologic, and Hematologic Diseases: The goals of this program are to increase the understanding of diseases and disorders of the kidneys, urinary tract, and blood (hematologic), and to develop and test prevention and treatment strategies. Basic, clinical, and translational research, as well as research training, is supported in the areas of chronic kidney disease (CKD), diabetic kidney disease, end-stage renal disease (ESRD or kidney failure), polycystic kidney disease, and many other kidney diseases; urinary incontinence, benign prostatic hyperplasia, interstitial cystitis/painful bladder syndrome, stones, impotence, congenital urologic disorders, and urinary tract infections; and disorders of the blood and blood-forming organs, including sickle cell disease, Cooley's anemia, hemochromatosis, and the anemia of inflammation and of chronic disease. Science-based information is communicated to patients, health professionals, and the public through NIDDK's National Kidney and Urologic Diseases Information Clearinghouse and National Kidney Disease Education Program (NKDEP). NIDDK is actively pursuing a range of research avenues related to kidney disease, acute kidney injury, CKD in children, hemodialysis, and other areas. Research efforts identified a novel biomarker associated with increased risk of kidney failure, cardiovascular disease (CVD), and death among people with CKD. Elevated levels of the biomarker are associated with increased risk of an adverse heart condition—change in the size of the heart's left ventricle.[21] Studies in animal models suggest that this biomarker may actually cause CVD, indicating that strategies to interrupt the biomarker's action could prevent or lessen damage to the heart in people with CKD. Translating knowledge into practice, NIDDK has funded five research groups to test the effectiveness of interventions for the prevention, treatment, and management of CKD that have a high likelihood of being widely adopted, and of being sustained in a wide range of health care settings and in individuals and communities at highest risk.
Budget Policy: The FY 2013 President's Budget request for this program is $417.591 million, a decrease of $0.756 million or 0.18 percent below the FY Enacted 2012 level. In FY 2013, NIDDK will continue support for ongoing major clinical studies of CKD in adults and children and fund new research to identify and validate biomarkers and risk assessment tools for patients with this condition. NIDDK also plans to continue to sponsor planning grants to conduct translational research on the effectiveness of interventions shown in clinical trials to prevent, treat, and manage CKD, and will continue to sponsor studies to improve adherence to medical therapy in adolescents with CKD. In FY 2013, NIDDK will continue studies to improve measurements of outcomes in lower urinary tract disorders of the prostate and urinary bladder. NIDDK will continue treatment trials for polycystic kidney disease (HALT-PKD study) and continue support for the Consortium for Radiologic Imaging Studies of PKD; results of these studies will help to define measures of kidney disease progression. Centers focused on kidney, urologic, and hematologic research will receive continued funding, as will research on acute kidney injury and a study of arteriovenous fistulas. NIDDK will also continue support for the Systolic Blood Pressure Intervention Trial (led by NHLBI) and for other efforts as part of an overall balanced research portfolio.
In addition to being at high risk for kidney failure or end-stage renal disease, people with chronic kidney disease (CKD) have an increased risk of cardiovascular disease (CVD). In 2001, NIDDK established the Chronic Renal Insufficiency Cohort (CRIC) Study to identify risk factors that predict loss of kidney function, as well as the development and worsening of CVD, in people with CKD. CRIC has recruited and is following nearly 3,900 racially diverse participants with CKD at 13 U.S. clinical sites. Because African Americans are at increased risk for kidney disease, as are people with diabetes, these groups are well-represented in the study. A wide range of studies is being conducted, including accurate assessment of kidney function, measurement of coronary calcium, retinal photographs, echocardiograms, genetic investigation, and assessment of dietary intake, among others. Study investigators are carefully collecting information about cardiovascular, peripheral vascular, cerebrovascular, and kidney-disease related events, as well as death. Data and specimens from the study will be stored in the NIDDK Central Repositories and serve as a national resource for other investigators who are interested in studying CKD and CVD. Recently, investigators, using data from CRIC, demonstrated that high levels of a hormone that regulates phosphate metabolism are associated with increased risk of kidney failure, CVD, and death among people with CKD. Results from CRIC studies, and other studies to identify biological "markers", can allow physicians to better predict how various diseases are likely to progress in different patients and thereby personalize treatments to improve their health.
Special Statutory Funding Program for Type 1 Diabetes Research: Complementing efforts of the Diabetes, Endocrinology, and Metabolic Disease program, the Special Program's goal is to foster improved treatment, prevention, and cure of type 1 diabetes, and its complications through basic, clinical, and translational research around six scientific goals: 1) identifying genetic and environmental causes of type 1 diabetes ($44 million); 2) preventing or reversing the disease ($ 13 million); 3) developing cell replacement therapy ($25 million); 4) improving management and care ($5 million); 5) preventing or reducing diabetes complications ($54 million); and 6) attracting new talent and applying new technologies to research ($9 million) (FY 2013 estimate dollars). Although focused on type 1 diabetes, aspects of this research are relevant to other autoimmune disorders, as well as type 2 diabetes. Both type 1 and type 2 diabetes share impaired function of insulin-producing beta cells of the pancreas along with potential complications, such as heart disease, stroke, blindness, kidney failure, nerve damage, and lower limb amputations. In 2011, NIDDK funded bold and creative research projects that confront major challenges in type 1 diabetes research, including autoimmunity, diabetes complications, and development of artificial pancreas technologies. SmartCells, Inc., which received support from NIDDK small business grants and made substantial progress in preclinical development of a new formulation of insulin, was recently acquired by Merck & Co, Inc., enabling this technology to be developed to its fullest potential. To bring new investigators to type 1 diabetes research, NIDDK re-launched a program to foster research training and career development for pediatricians specializing in childhood diabetes. NIDDK is also creating a new training program to support and develop behavioral scientists and bioengineers in careers in diabetes research.
Budget Policy: The FY 2013 President's Budget request for the Special Statutory Funding Program for Type 1 Diabetes Research is $150 million, the same as FY 2012 Enacted level. NIDDK administers the program, but because of its trans-HHS nature, the resources are disbursed among multiple NIH Institutes and Centers as well as the CDC. Building on planning grants awarded in FY2012, clinical trials to develop practical approaches to improve the health of people with type 1 diabetes and prevent diabetes complications will be implemented in FY2013 ($50 million). Among ongoing efforts that will continue with FY 2013 funds are studies to identify environmental causes of type 1 diabetes in genetically susceptible individuals as a basis for the development of a vaccine or other preventative intervention and trials to test approaches to prevent or slow the onset of the disease. ($47 million), the Clinical Islet Transplantation Consortium ($3.2 million), and the Beta Cell Biology Consortium, which aims to regenerate or replace the insulin-producing cells of the pancreas ($19 million). FY 2013 funds will also support fundamental research to uncover the etiology and pathogenesis of type 1 diabetes ($15.3 million). Research on development of artificial pancreas technologies will continue in FY 2013 through initiatives funding small business research to develop new therapeutics and monitoring technologies for type 1 diabetes ($4.2 million) and clinical research on closed-loop technologies ($4.2 million). FY 2013 funds will also foster research and early career development for pediatric endocrinologists, behavioral scientists, and bioengineers studying new approaches to treat, prevent, and cure type 1 diabetes ($7.1 million).
Intramural Research: The goal of the Intramural Research Program (IRP) is to conduct basic, translational, and clinical biomedical research related to diabetes and other endocrine and metabolic diseases; digestive diseases, including liver diseases and nutritional disorders; obesity; kidney diseases; and hematologic diseases. Intramural research is conducted in the Institute's laboratories and clinical facilities in Bethesda, Maryland, as well as in Phoenix, Arizona, where a long-standing research relationship with the Pima Indians in the region, who have the highest rate of diabetes in the world, has led to important scientific advances in type 2 diabetes and obesity. Research training is also an integral component of the IRP. Recently, the NIDDK IRP developed a mathematical model that more accurately predicts weight loss for adults, revealing that weight loss in adults happens slowly over longer periods of time than previously expected.[22] NIDDK IRP research found that African Americans with two copies of certain genetic variants in the APOL1 gene are at increased risk of developing kidney disease, particularly focal segmental glomerulosclerosis and kidney disease related to infection with the human immunodeficiency virus.[23] Recent IRP studies identified a small molecule that inhibits the unregulated cellular mechanism that gives rise to Graves' disease,[24] and showed that a dietary supplement, S-adenosylmethionine, safely and effectively boosts response to standard therapy in people infected with a type of hepatitis C virus that typically does not respond well to therapy.[25] Other IRP research determined the detailed structure of the A2A adenosine receptor which has the potential to speed drug discovery in many disease areas,[26] and discovered key features of hotspots associated with genetic rearrangement that leads to genetic diversity which has the potential to improve detection of genes linked to disease and help understand the causes of genetic abnormalities.[27]
Budget Policy: The FY 2013 President's Budget request for this program is $179.593 million, the same as FY 2012 Enacted level. With FY 2013 funds, the NIDDK IRP will continue a broad spectrum of research studies to strengthen understanding of basic biology and disease mechanism, and evaluate potential therapeutics approaches. For example, in FY 2013, intramural scientists will continue research on obesity in the trans-NIH Metabolic Clinical Research Unit, as well as research relevant to diabetes; digestive diseases, including liver disease; kidney disease; and hematologic disease. The program will also continue to support research training.
Research Management and Support (RMS): RMS activities provide administrative, budgetary, logistical, and scientific support in the review, award, and monitoring of research grants, training awards, and research and development contracts. RMS functions also encompass strategic planning, coordination, and evaluation of the Institute's programs, regulatory compliance, international coordination, and liaison with other federal agencies, Congress, and the public. Through its RMS activities, NIDDK has continued to fund meritorious basic, clinical, and translational research and research training efforts, and also continued its health information dissemination and education/outreach activities. Additionally, NIDDK's strategic planning, evaluation, and other activities have continued.
Budget Policy: The FY 2013 President's Budget request for RMS is $65.878 million, the same as FY 2012 Enacted level. NIDDK will continue effective research management and support so as to deploy research resources to the most meritorious and promising areas, and to communicate research opportunities and findings to investigators, health professionals, and the public.
* Includes FTEs which are reimbursed from the NIH Common Fund.
Page last updated: February 13, 2012


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With the move 1.c4, you can avoid some of the openings and lines to be feared after 1.d4. Following 1.c4 e5 – this move order is also called reversed Sicilian – arises an independent opening which, however, still leaves space for many transpositions. To deal with the vast amount of material requires expert skill and great knowledge of the variations, both qualities distinguishing the author, Grandmaster Mihail Marin. The total number of 69,000 games on the CD shows the gigantic field he managed to cover. His enormous work is reflected in no less than 60 database texts and 330 games, exclusively annotated for this CD. Further more, there is a training database with 46 games.
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This rollicking, rhyming PBS StoryTime favorite is a counting book, an animal identification book, and a book with lots of food and fun! But most important, each child will come away knowing that, "...there will always be room at the Palace for you."
"…bouncy, rhyming verse and an innovative cast of characters give this counting book zip…" -- Publishers Weekly
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Kids will laugh their way through this interactive story while learning about school routines. What will Ollie do at story time? Will he practice playing the kazoo? NO! Will he go for a swim in the sink? NO! Will he put on skates and zip around the room? NO! Find out what Ollie does in this highly acclaimed book.
"Calmenson...savvily encourages the youngest listeners to chime in and be part of the reading process...Will this be a popular and raucous first-day-of-school favorite? YES!" -- Kirkus, starred review
When the weather gets cold And a mouse slips in, A jazzmatazz story Is sure to begin…
Meet a piano-playing mouse, a dog with drums, a cat with a fiddle, a bird who sings, a fish who blows musical bubbles and one great tap-dancing kid! What kind of music will you make? Doo-dat, ditty-dat, doo!
"...a bright, syncopated jam session sure to please storytime audiences." -- Kirkus Reviews
Uh-oh! Mr. Bungles has overslept and he's going to be late for school. Teachers aren't supposed to be late! He tries rushing by car, train, bus even by unicycle and hot air balloon. The clock is ticking. What will he try next?
"This laugh-and-a-half book gets its kick from well-structured rhyming text and fruit-colored, in-your-face pictures. Fun for children and teachers alike." -- Booklist
Even the best teachers can have an oopsy day. Mr. Bungles gets out of bed and bumps his head. He drips jam on his tie and gets soap in his eye. He lets the class hamster Nibbles escape, and leads his students on a wild chase all around the town. The students love their teacher, Mr. Bungles. In this shout-out-the-word story, he shows them how to make school fun!
"The accident-prone teacher who first appeared in Late for School is back...for breathless, laugh-filled storytimes." -- School Library Journal
Do you like dogs? Would you like to meet some, pet some, see some tricks? Stephanie Calmenson's own dog, Harry, will show you how. The first thing to remember is: Always ask MAY I PET YOUR DOG?
"Dachshund Harry leads…readers through every step of kid-meets-dog etiquette...most engaging…is the direct address from dog to child." -- Horn Book, starred review
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Radio Interviews and Appearances
Read about Rosie, the author's sweet and shaggy dog, as she cheers people who are sad or sick or lonely. Find out if you can join a visiting program, with or without a pet of your own. And let Rosie cheer you.
"Rosie's real-life adventures make for one of the outstanding nonfiction titles of the year." -- Smithsonian Magazine
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Do you like Golden Retrievers? Beagles? Yorkies? Catchy rhymes describe these dogs and 22 more, with a surprise at the end. Find out if you're right for a dog and which dog is right for you.
"… snappy four-line rhymes reflect a joy in and love of dogs as they spotlight more than 20 canine breeds..." -- Booklist
Kindergarten is so much fun and there's lots to learn. Kids will love these interactive poems that give them a taste of a kindergarten day with Show and Tell riddle rhymes; a search for a missing class pet; a pizza party; a popcorn dance; a 100th Day of School celebration and more!
"…the text…delivered in rhyme, details the fun to be had in kindergarten..." -- Publishers Weekly
Mr. Bundy, principal of P.S. 88, is the sharpest dresser in town. Two tricksters want to sell him a suit that isn't there. One student is brave enough to tell the truth -- thank goodness! Read this story and laugh!
"The whole school should chortle with glee over this one!" -- Kirkus
In this hilarious sequel to The Principal's New Clothes, a bumbling magician turns P.S. 88's beloved principal, Mr. Bundy, into a frog, then finds he can't turn him back again! See what it's like to have a frog for a principal. Ribbit!
"...ribbit-tickling companion to The Principal's New Clothes..." -- Kirkus Reviews
A teeny tiny teacher finds a teeny tiny bone that belongs to a teeny tiny ghost who wants it for his teeny tiny... Read the story and find out. Life size children are invited to join the chant-along fun.
"...could easily become a story-hour favorite." -- Kirkus
Move over Mother Goose! These catchy rhymes are keepers! They're all about babies and things babies do. This is the perfect baby gift on its own or paired with GOOD FOR YOU! Toddler Rhymes for Toddler Times.
"Colorful and childlike…A fine alternative to board books and nursery rhymes.." -- Booklist
GOOD FOR YOU! Toddler Rhymes for Toddler Times pictures by Melissa Sweet
Twenty-five irresistible rhymes zoom in on a toddler's world. Youngest readers are invited to play, sing, join an alphabet parade and, most of all, feel good about themselves!
"...Joyously exuberant, Calmenson's verses enlighten and entertain." -- Kirkus Reviews
Mr. Panda is throwing a birthday party for Mouse and you're invited! Friends arrive with packages. What's in them? Catchy rhyming riddles help you guess the answers. And wait! Mr. Panda has a special surprise. Come join this celebration of friendship and fun. Fans have been clamoring for a sequel to the PBS StoryTime favorite, Dinner at the Panda Palace and now it's here! Par-ty! "...a popular theme and winning ending emphasizing a friendship's reunion…will encourage repeated readings with gleeful shouts at the appropriate time." -- Kirkus
Some people -- and puppies -- think they have to be perfect. Some people -- and puppies -- learn they can make mistakes and still be loved very much. Meet a puppy you'll fall in love with -- mistakes and all.
"…warm story of acceptance, mistakes and all." -- Horn Book
There's no better way to learn the alphabet than with these catchy riddle rhymes. Try one!
This food starts with S. It's long and it's thin. I eat it with tomato sauce that drips down to my chin. What is it?
"A clever new alphabet book in riddle form ..." -- Booklist
Listen to me! Listen to me! Clickety-clack! Watch for me! Watch for me! Coming down the track. What am I?
Find word and picture clues on one page, answers on the next. Youngest readers love guessing games and will feel proud of each success.
"Catchy, rhyming riddles about familiar objects will delight young audiences…" -- Sesame Street Magazine
Zip, whiz, zoom! Honk, whirr, vroom! Toot-toot. Beep-beep. Boom-de-boom!
Follow an assortment of people dressed up and carrying gifts as they drive, fly, sail, bike to a surprising destination. Noises, vehicles -- and family -- are at the heart of this book.
"...simple, breezy verse invites...audience's participation." -- Publishers Weekly
Engine, Engine, Number Nine, Rolling, rolling down the line. Wheels are turning. Whistle's blowing. Soon we'll find out where it's going. In this rollicking rendition of a traditional children's rhyme, grown-ups, kids, an assortment of animals and a whole marching band board a train heading for… Read the book to find out. All aboard!
"...a definite read-aloud... will soon have even the youngest singing along." -- Children's Book Review Service
It's a special day when Grandma takes Marigold out on the town! There are a few problems along the way, but Grandmas always know how to solve them.
"This simple, sweet tale of a young bunny and her granny displays a genuine grasp of what children find funny." -- USA Today
"I'm hotter than a hot dog in a campfire!" I said. "I'm hotter than a salamander in the sun!" said Granny.
Word play. Hot day. Grandma's got a great idea to cool things off. Hop on the train -- the iron dragon -- and see where it takes you.
"Sweet, funny, and right on the mark ..." -- Booklist
This is a warm, furry -- and funny! -- story of love and friendship. If you've seen the movie "You've Got Mail!", or the musical, "She Loves Me!" you'll know how it all turns out.
"Hare hilarity ... The telling is delicious ..." -- Publishers Weekly
Meet the Gator Girls -- Ali, Amy and Gracie. Meet the Gator Guys -- Marvin and Dave. Follow their adventures in these FUNNY, easy-to-read chapter books!
"…will tickle children's funny bones... fun and easy to read." -- School Library Journal, starred review
THE READ-ALOUD TREASURY Favorite nursery rhymes, poems, stories, and more for the very young BUG IN A RUG Reading Fun for Just-Beginners READY...SET...READ! The Beginning Reader's Treasury READY, SET, READ...AND LAUGH! A Funny Treasury for Beginning Readers GIVE A DOG A BONE Stories, Poems, Jokes and Riddles about Dogs THE LAUGH BOOK A New Treasury of Humor for Children THE SCARY BOOK
EENTSY WEENTSY SPIDER Fingerplays and Action Rhymes SIX SICK SHEEP: 101 Tongue Twisters WHY DID THE CHICKEN CROSS THE ROAD and Other Riddles Old and New YOURS TILL BANANA SPLITS: 201 Autograph Rhymes PIN THE TAIL ON THE DONKEY and Other Party Games CRAZY EIGHTS and Other Card Games THE RAIN OR SHINE ACTIVITY BOOK Fun Things to Make and Do FUN ON THE RUN Travel Games and Songs MARBLES: 101 Ways to Play
The Gator Girls series (see above)
The Baby-sitters Little Sister Books over 75 titles with Ann Martin Sesame Street CTW Disney Movie Tie-ins


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Spring 2013 - Volume 19
featured authorThis issue features new work by Micheal Martone, author of Fort Wayne is Seventh on Hitler's List, Four for a Quarter, and many other books.
fictionAndrew Bourelle, Xerxes
Brian DiNuzzo, The Censor John Haggerty, Big Bitch Material Kevin Tosca, When We All Grow Up nonfictionJacqueline Doyle, Meta-Fictional Pasta
George Korolog, An Observation at the Conjunction of Black Holes and Crickets |
poetryCaylin Capra-Thomas, I Could Tell You Again
Kevin Carollo, Purr William Cordeiro, Wrack Lines Mark DeCarteret, Birdwatching for Beginners Kent Leatham, Air Ross Losapio, I Knew Nadra Mabrouk, Virgin Jonathan McClure, Photograph Ellen Birkett Morris, Last Words Martin Ott, Goodnight Derek Palacio, Elegy for the Stem Esteban Rodriguez, Goldfish Kate Rosenberg, All Night Architecture Kirk Schlueter, 14 Ways of Watching Randy Johnson Kill a Dove With a Fastball and many others... |
For Tanzanite
William Snyder We see boys and men waiting for shifts— squatting, lying on the dry ground, standing. No shade but the mine shaft roof and a strip beneath the diesel huffing air down a thin, gray hose. Three-hundred meters, they tell us, and out in every direction—tunnels meeting tunnels, over and under—the mine's deep snarl. Thirty-seven miners, they say, crushed last month, crushed deep in child-sized shafts—the buckle of bamboo pole, the snap of sapling strut, the crush of slack, red earth. Read More >> An Observation At The Conjunction Of Black Holes and Crickets George Korolog Now, this observation is being hung directly in front of your face, like a dare, suspended like plump, ripe mulberries gripping the secret stems of the sky, even though the heavens have long forgotten this pitiless clinging and have methodically moved on to choose more exotic objects, new textures of interest, new things moving and brimming, right now, from the mysterious boundary of the very first light all the way back to the top of the troposphere. Read More >> |
Michael Martone In 1925, flying over North Highlands, with his mother, Ida, on board, Art Smith, The Bird Boy of Fort Wayne, negotiated a crash landing after the motor driving his DeHaviland choked. Read More >> The Censor
Brian DiNuzzo My eyes hurt some when I rub them, and when I close my eyes I see my computer screen. It is a good night for a drink but all we have is wine and the feeling fades. The question Why haven't I married Catherine? is always hanging around, the way that censoring hangs around as the only job I'll ever have. Catherine's neck muscles are tight and my hands disappear under her constrictor curls. Clapton fades out. Catherine sinks back, rests her head against my chest. From this angle, her nose is pointed like a capital A turned on its side, and her eyes are vats of fresh oil. Is this what Catherine looked like when she was young? When she looks up at me, I flinch. From her angle, she must be seeing an older me—my chin doubled, my teeth crooked, my nostrils like industrial vacuums. Catherine shoots up, wincing. "Ouch. You hurt." She moves her hair to soothe her inflamed neck. "It felt good for a while, then it just hurt." She is turning and twisting and nodding her head, making sure I haven't damaged her. I apologize and think, This is why I haven't married you. |


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Carlisle Wide Plank Floors
If you've ever taken a drive along the Eastern seaboard, chances are you've seen a run-down old barn or mill. Would you ever guess these buildings are the source of beautiful reclaimed wood floors? Carlisle, a wide-plank flooring company, selects the highest quality wood from such structures, cuts it into usable planks, and mills it to perfection. The end result is a one-of-a-kind floor that maintains its original character through unique details like nail holes, knots and splits.
What once appeared as minor imperfections transform into beautiful floors unlike anything that can be manufactured today. Carlisle is certified by the Forestry and Stewardship Council (FSC) for its environmentally green forestry practice and is also recognized for its sustainability. Reclaimed wood floors not only contribute to the aesthetic of a room, they also bridge the gap between past and present and hark back to an age of unparalleled craftsmanship. For more, visit http://www.wideplankflooring.com


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Toaster Oven Biscuits :: Savory Biscuits
2 C. flour1 Tbsp. baking powder1/4 tea. baking soda1 tea. salt1/2 C. sugar1 tea. grated orange rind1/3 C. vegetable shortening1 egg, beaten3/4 C. buttermilk1/2 C. fresh or frozen blueberries3 Tbsp. melted butter or margarine3 Tbsp. sugar1/8 tea. cinnamonDash of nutmeg
In med. bowl, mix flour, baking powder, baking soda, salt, sugar and orange rind together. Using a pastry cutter or two knives, cut the vegetable shortening into the flour mixture until it resembles coarse meal.
In sm. bowl lightly beat egg with fork. Add the buttermilk to the beaten egg, then add it to the flour mixture. Using a fork, stir until just moistened. Add the blueberries. Stir gently just to mix. Turn dough out onto floured surface or cloth and gently knead 3 or 4 times. Roll out to 1/2-in. thickness. Cut with biscuit cutter or into desired shapes. Place on lightly prepared cookie sheet and bake at 400 degrees F for 15 min. or until golden.
Mix butter with sugar, cinnamon and nutmeg and brush onto tops of biscuits as they come from the oven.
Makes approximately 12 to 15 biscuits.


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- February 16, 2011
- 1:51 p.m.
- Suggest removal
- Reply to this post
Civil_E writes:
Will each member of the family have to pay the $30 per year? If it is tied to a license plate, how are bicyclists providing proof of payment? Will we be given stinking badges?
Want to participate in the conversation? Become a subscriber today. Subscribers can read and comment on any story, anytime. Non-subscribers will only be able to view comments on select stories.


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True Crime Library teaches you safety tips for women - things you should never do and things you should do - things that could save your life. It's far better to know them and not need them, than to need them and not know.
Learn lessons from crime victims and survivors - lessons that your mother never taught you.
Charity Gibson parked at her Daytona Beach FL apartment building and saw a suspicious man walking toward her car. She decided to get out and face him. The man pointed a handgun at her and demanded her purse and that she get in her car's trunk. As she crawled into the trunk, she remembered her new car had a glow-in-the-dark release latch inside the trunk. As soon as she felt the car slow down, she jumped out of the trunk and landed on the pavement.
Ms. Gibson made split-second decisions to escape, but a True Crime Library Review has the luxury of leisurely analyzing how she could have improved her survival odds.
First, Ms. Gibson should've driven away OR stayed IN her locked car and blown the car's horn nonstop rather than getting out to face him. Loud noise, especially before the crime has truly begun, usually scares away criminals. See Escaping Carjacking.
Second, since Ms. Gibson had already exited her car, she would've been better off dropping her car keys and running away – letting him have the car but not have her.
There's only a 12 percent chance that a robber will call attention to himself by firing a gun in a populated area and only a 3 percent chance of hitting you fatally (per the USDOJ). Moreover – now think about this: if he's willing to kill you on the spot, he's likely to do worse at a secluded, secondary crime scene. See Spotting Danger > How He Reaches For A Weapon and Survival Options - Kidnapping.
Nevertheless, Ms. Gibson wisely escaped before the car had gained much speed. Her bravery may well have saved her life – and certainly taught us a lifesaving lesson.
Her husband was home but neither he nor her neighbors heard her screams for help. And her best friend, with whom she'd been talking on her cell phone, was unable to help. She lost faith in her fellow man and still struggles to believe that not every stranger walking toward her wants to kill her.
See Predators Favorite Targets (distracted) and Post-Traumatic Stress Disorder (PTSD) on Crime Survivors Overview.
Sometimes Talking Works:
The victim habitually went for a morning jog for many years. The rapist watched her for a while to know where she was going next. Bradley Scott Sneed tackled her from behind and dragged her under a fence. At first she was screaming, but he became more violent. So she began talking him down, asking what he wanted. He told police that's why he didn't rape her.
Sometimes Talking Does NOT Work:
13-year old Esme Kenney was jogging and literally ran into serial killer Anthony Kirkland, spilling his beer. She apologized. Kirkland said he beat the girl and raped her. She didn't scream or fight. Instead, she just talked to him. She asked if he had children. That's when Kirkland said he saw the hated mother of his son and he killed the girl.
You must learn how to talk to your attacker at Verbal Self Defense. Also see Victim's Options Overview of fight or flight – or talking your way out of danger.
Some people are paralyzed in a crisis, while others try to connect with the criminal, hoping he'll be less willing to hurt them. However, many victims choose to submit – hoping for the best. Victims should do whatever it takes to survive by trusting their intuition. Although victims who'd killed a criminal often experience PTSD, they know they did what they had to do to survive.
See Stress Control - Fear Itself: fear, panic, and courage.
Learn how to deal with the risks of hired help in Home Security - Cracks.
Choose how safe you want to be. Look at your home through a burglar's eyes and improve the worst area first. See Home Security Overview. The most important areas are fortified doors and windows, good lighting, and alarms, and, especially, your entire family's cautious behavior. No group is any safer than its most careless member – just one weak link can endanger all of you.
Carry Pepper Spray & a Personal Security Alarm (noisemaker or screamer) within easy reach. Those pages tell you how to use them most effectively.


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Superior Collaborations
Are you ready to get your business out in the world in a major way, but don't know where to start?
Are you spending countless hours trying all the new online marketing trends and still not getting the results you want?
Here at Superior Collaborations, we have the answer to solve one of your worst problems…not having enough time to accomplish everything you desire!
You probably realize that the tasks won't take too much time, but you would rather be spending your time growing your business and making more money than taking care of what you despise.
Do you need a couple more hours each day, have heard of virtual assistants, but don't know if you can afford one? Oh…and how do you know if it is the right one for you…don't want to make that mistake!
How about spending more time with your family and less time with your business while still making money?
Superior Collaborations can give you all that and more! Let us help by handling your administrative duties for you. We will give you back those lost hours in each and every day, so you can focus on what is most important to you and your business.
What can you expect from your partnership with Superior Collaborations?
- Business Growth
- Extra time in your day to spend on what matters most to you
- Shorter to-do list
- Expertise of a seasoned assistant with the right training and certifications for your projects (and connections in the industry for any projects that we don't handle ourselves that we can recommend to you)
- Peace of mind that your projects are being handled in a timely, accurate and confidential manner
- Recommendations for what will work in your business
- Systems to be implemented in your business to make it run smoothly no matter what day or time it is
- Not just problems being presented to you…SOLUTIONS to those problems
- Self starter…we take your business seriously, as if it were our own. We won't be coming to you constantly to answer questions or tell us what to do. Once you go over the tasks we take it from there!
So go ahead…go to that networking event, or better yet, take the rest of the afternoon off. That spreadsheet that needs to be done will be taken care of while you are gone!
Contact Superior Collaborations today for a free consult. We can discuss your needs.


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- Big storm dumps snow on East Coast, travel dicey
- Thai prime minister dissolves Parliament, calls elections
- Hagel to meet with Pakistan's prime minister
- Kiev: Riot police deployed near protest sites
- Elton John blasts Russia's anti-gay laws during Moscow concert
- U.N.: Afghanistan slow to enforce law protecting women
- Heart cancels SeaWorld concert after 'Blackfish' documentary
- South Carolina sheriff refuses to lower American flag for Nelson Mandela
- South Africans hold day of prayer for Nelson Mandela
- Mandela not on life support in final hours, friend says
Kronos Quartet, Patti Smith accept Swedish prize
STOCKHOLM (AP) - American string quartet Kronos Quartet and rocker Patti Smith have received the prestigious 2011 Polar Music Prize from Sweden's King Carl XVI Gustaf.
The musicians accepted their awards at a glitzy ceremony in Stockholm on Tuesday. Each award is worth 1 million kronor ($159,000).
A moved Smith said she was "humbled and inspired" to receive the award. She thanked her family and band members and appealed to the audience to "turn their hearts and minds and resources" toward the famine in Africa.
The Polar Music Prize is typically shared each year by a pop artist and a classical musician. It was founded by the manager of Sweden's legendary pop group ABBA, Stig Anderson, in 1989.
Previous laureates include Pink Floyd, Joni Mitchell, Bjork and Sir Paul McCartney.
CHELLANEY: China's game of chicken
By Brahma Chellaney
Beijing's creeping aggression signals a challenge to U.S. presence in the Asian Pacific
- Lawmakers see 'false narrative' of Obama as a terrorist fighter
- CURL: Obama tells a whopper on IRS scandal
- EDITORIAL: Health care hardball
- Sen. Rand Paul: Supreme Court needs to re-examine Fourth Amendment
- Rush Limbaugh: Obama trying to make Mandela death about himself
- South Carolina sheriff refuses to lower American flag for Nelson Mandela
- Redskins' season hits bottom with Chiefs blowout
- POWELL: The Fed's scandalous monetary policy
- Obamas call to close Vatican embassy is 'slap in the face' to Roman Catholics
- China and other heavy polluters contribute little to restitution fund for emerging markets
Independent voices from the The Washington Times Communities
TV Den
Television commentary, reviews, news and nonstop DVR catch-up by Lisa King Dolloff and friends.
Red Pill, Blue Pill
Al Maurer provides a common sense, conservatarian, Constitutional conservative perspective from the battleground state of Colorado
The Last Frame
Film Reviews and Articles by Kevin Williams
Consider Again
"Critical thinking is thinking about your thinking while you're thinking in order to make your thinking better." - Dr. Richard Paul


text: Behold the official Civilization V trailer, coming out in the fall of 2010. Everything you see in the trailer is in-game footage. Jokes! What you see is a teaser trailer for the venerated RTS franchise, replete with awesome voice over work from Keith David. Can't wait to see what updates and innovations are included in this game.


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Zetas Associate Arrested For Attempted Bribery
AUSTIN, Texas (AP) - A man convicted of laundering money for the Zetas drug cartel is now accused of conspiring with his son and a business associate to bribe a federal judge in return for a light sentence.The son, Francisco Colorado Cessa Jr., and business associate Ramon Segura Flores appeared before a federal magistrate Friday for allegedly conspiring to offer a $1.2 million bribe to Judge Sam Sparks. Francesco Colorado Cessa is also charged in the alleged bribery plot.
The allegations came after Sparks sentenced Colorado Cessa to 20 years in prison for his role in spending nearly $25 million to buy and sell racehorses to launder drug money. The men did not enter a plea Friday. Defense attorney Mike DeGeurin, who is representing all three men, declined to comment.


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Welcome to Bethel! We are a family-friendly church that takes seriously our responsibility to help people discover God and then journey with Him. We recognize the many views and opinions about spirituality that surround you today – and we want you to know that while we certainly don't claim to be perfect, we do base our teachings upon a reliable and trustworthy source – the Bible. If you have questions, please do not hesitate to contact us. We want to help you grow with God and we believe that God calls us to serve you in that purpose. |
Sunday Service
Ministries at Bethel |
Learn More About Us |
What is Here for Families |
How To Connect |
Sundays & Beyond |
Reaching Out to Others | |
››Close‹‹ |


text: Prepared Statement of the Federal Trade Commission FTC Merger Enforcement in the Gasoline Industry Presented by Chairman Robert Pitofsky Before The Committee on Commerce, Science, and Transportation April 25, 2001 I. Introduction Mr. Chairman and members of the Committee, I am Robert Pitofsky, Chairman of the Federal Trade Commission.(1) I am pleased to appear before you today to present the Commission's testimony concerning the important topic of competition in the gasoline industry in West Coast markets. Competition in the energy sector - particularly in the petroleum industry - is vitally important to the health of the economy of the United States, and to the various regions of the country. Our experience has taught us that gasoline markets can be much narrower than the entire country, and the West Coast markets have their own particular features that set them apart from the rest of the country. In all markets, antitrust enforcement has an important role to play in ensuring that the gasoline industry is, and remains, competitive. Merger enforcement in particular has recently been at the forefront of efforts to maintain and protect a competitive environment in various gasoline markets, and our testimony today is directed at that ongoing effort. The FTC is a law enforcement agency with two distinct but related missions: preserve competition in the marketplace through antitrust law enforcement and protect the consumer from unfair or deceptive acts or practices. The Commission's statutory authority covers a broad spectrum of sectors in the American economy, including the companies that comprise the energy industry and its various components. Among the statutes the Commission enforces are two antitrust laws, the FTC Act(2) and the Clayton Act.(3) The Commission shares jurisdiction with the Department of Justice under section 7 of the Clayton Act, which prohibits mergers or acquisitions that may "substantially lessen competition or tend to create a monopoly."(4) Under section 5 of the FTC Act, the Commission prohibits "unfair methods of competition" and "unfair or deceptive acts or practices." II. Level of Merger Activity It is no secret that merger activity in the United States is at an all-time high. The number of mergers reported to the FTC and the Justice Department pursuant to the Hart-Scott-Rodino Act has more than tripled over the past decade, from 1,529 transactions in fiscal year 1991 to 4,926 transactions in fiscal 2000. Although filings have declined so far this year because of higher filing thresholds(5) and the slowing economy, the Bureau of Competition remains heavily focused on merger work. Currently, more than two-thirds of our competition resources are dedicated to merger enforcement, compared to an historical average of closer to 50 percent. While the number of merger filings has more than tripled in the past decade, the dollar value of commerce affected by these mergers has increased an astounding eleven-fold during the same period. But mere numbers do not fully capture the complexity and the challenge of the recent merger wave. Today's merger transactions not only are larger, but often raise novel or complex competitive issues requiring more detailed analysis. In the past year alone, companies filed notifications for 288 mergers with a transaction size of one billion dollars or more, and many of these mergers involved overlaps in several products or services. There are many reasons for the current merger wave. A large percentage of these transactions appear to be a strategic response to an increasingly global economy. Many are in response to new economic conditions produced by deregulation (e.g., telecommunications, financial services, and electric utilities). Still others result from the desire to reduce overcapacity in more mature industries. The rapidly evolving world of electronic commerce has a substantial impact on the merger wave, because consolidations often quickly follow the emergence of a new marketplace. These factors indicate that the merger wave reflects a dynamic economy, which, on the whole, is a positive phenomenon. But some mergers, as well as some other forms of potentially anticompetitive conduct, may be designed to stifle competition in important sectors of this dynamic economy. III. Merger Enforcement in the Gasoline Industry Out of necessity, our scarce resources are directed at preserving competition in the most important areas of the economy. The Commission dedicates the bulk of its antitrust enforcement to sectors that are critical to our everyday lives, such as health care, pharmaceuticals, retailing, information and technology, and, in particular, energy. Much of the Commission's experience with enforcing the antitrust laws in energy industries has been in analyzing mergers.(6) Merger enforcement is the first line of defense in protecting a competitive marketplace, because it preserves rivalry that brings lower prices and better services to consumers. The Commission blocks or obtains relief in those mergers that increase the likelihood that the merged firm can unilaterally, or in concert with others, increase prices or reduce output or innovation. The Commission has an extensive history of carefully investigating mergers in the energy industries, particularly petroleum, and the FTC has challenged mergers in those industries that would be likely to reduce competition, result in higher prices, and injure the economy of the nation or any of its regions.(7) In each merger investigation, the Commission will intervene if the consummated merger would significantly reduce competition in any sector of an industry that affects the United States or its citizens. The specific question the Commission must ask is whether the result of a merger "may be" - i.e. it would be reasonably likely - that the remaining firms in the industry could reduce output and raise prices to the detriment of consumers anywhere in the United States. The Commission approaches its antitrust mission by examining the areas in which merging companies compete, looking at the existing state of competition in that marketplace and the likely changes in that marketplace in the future, both from new competition entering and from existing competition exiting. We also look at the effect of recent mergers on competition in the particular marketplaces at issue, and whether the merger is a part of a trend towards concentration that limits competition.(8) The Commission has recognized the existence of such a trend toward consolidation in the petroleum industry.(9) On the other hand, many mergers actually increase competition. So, the Commission also considers efficiencies in deciding whether to challenge an otherwise anticompetitive merger because they may counteract the merger's threatened anticompetitive effects. However, the Commission engages in a rigorous analysis of efficiencies. Merely claiming cost savings is not enough to allow an anticompetitive merger; they must be proven. The Commission demands that cost savings of the merger be real and substantial; they cannot result from reductions in output; they cannot be practicably achievable by the companies independent of the merger; and they must counteract the merger's anticompetitive effect, not merely flow to the shareholders' bottom line.(10) Protecting competition and consumers is the goal of antitrust enforcement across all industries; its importance is particularly clear in the energy industry, where price increases can have a direct and lasting impact on the entire economy. Towards that end, the Commission has expended a substantial part of its resources in recent years in addressing the wave of consolidation in the petroleum and gasoline industry. In fiscal years 1999 and 2000, the Bureau of Competition spent almost one-third of its total enforcement budget on investigations in energy industries, and that level of effort has continued into 2001. Our merger review investigations revealed that several of these transactions threatened competition in local or regional markets. In those instances, the Commission allowed the merger only after demanding significant changes that would fully restore the competition lost as a result of the merger. The Commission's investigation of the merger between Exxon and Mobil highlights many of the issues, and difficulties, in large oil company mergers. After an extensive review, the Commission required the largest retail divestiture in FTC history - the sale or assignment of 2,431 Exxon and Mobil gas stations in the Northeast and Mid-Atlantic regions, and in California, Texas and Guam.(11) The Commission also ordered the divestiture of Exxon's Benicia refinery in California; light petroleum terminals in Boston, Massachusetts, Manassas, Virginia, and Guam; a pipeline interest in the Southeast; Mobil's interest in the Trans-Alaska Pipeline; Exxon's jet turbine oil business; and a volume of paraffinic lubricant base oil equivalent to Mobil's production. The Commission coordinated its investigation with the Attorneys General of several states and with the European Commission (about 60% of the merged firm's assets are located outside the United States). There are several particularly noteworthy aspects of the Exxon/Mobil settlement. First, the divestiture requirements eliminated all of the overlaps in areas in which the Commission had evidence of competitive concerns. Second, while several different purchasers ended up buying divested assets, each purchased a major group of assets constituting a business unit. This replicated, as nearly as possible, the scale of operations and competitive incentives that were present for each of these asset groups prior to the merger. Third, these divestitures, while extensive, represented a small part of the overall transaction. The majority of the transaction did not involve significant competitive overlaps. In sum, we were able to resolve the competitive concerns presented by this massive merger without litigation. The Commission also required divestitures in the merger between BP and Amoco,(12) and in a joint venture combining the refining and marketing businesses of Shell, Texaco and Star Enterprises to create at the time the largest refining and marketing company in the United States.(13) BP/Amoco involved very large companies but relatively few significant competitive overlaps. There was competitive concern in a few local markets. The Commission ordered divestitures and other relief to preserve competition in the wholesaling of gasoline in 30 cities or metropolitan areas in the eastern and southeastern United States, and in the terminaling of gasoline and other light petroleum products in nine geographic markets. The Shell/Texaco transaction raised competitive concerns in markets for gasoline and other refined petroleum products in the Pacific Northwest (Oregon and Washington), California, and Hawaii, for crude oil in California, and in the transportation of refined light petroleum products to several southeastern states. The two companies had substantial market overlaps. Both Shell and Texaco owned refineries in Puget Sound and, between them, made about 50 percent of the gasoline refined in the Puget Sound area. The Commission alleged that eliminating direct competition between those refineries could result in price increases for gasoline and jet fuel in the Pacific Northwest and California of more than $150 million per year. The Commission, in conjunction with the Attorneys General of California, Washington, Oregon, and Hawaii, required the divestiture of a refinery in Anacortes, Washington, which was a major supplier of refined products to Oregon via the Olympic pipeline; a terminal on the island of Oahu, Hawaii; retail gasoline stations in Hawaii and California; and a pipeline interest in the Southeast. During 1999, the Commission investigated the proposed $27 billion merger of BP Amoco ("BP") and ARCO, the two largest competitors for the production, delivery, and sale of Alaska North Slope ("ANS") crude.(14) BP was the largest producer of ANS crude and the largest supplier to various West Coast refineries. ARCO was the second largest ANS producer. The Commission conducted its investigation in cooperation with the Attorneys General of Oregon, Washington, and California. As part of that investigation, the Commission looked at the West Coast crude oil market to determine if the acquisition would increase the likelihood that the merged firm would be able to exercise market power, either unilaterally or in conjunction with other firms. The Commission found reason to believe that BP was already exercising market power in the production and sale of ANS crude oil to refineries on the West Coast, and that the merger would increase BP's ability to keep ANS prices high by eliminating the one firm with the ability and incentive to produce and sell more ANS crude oil. The Commission's investigation revealed that BP was able to discriminate in price by charging some West Coast refineries higher prices than others, based on the ability of some refineries to substitute more easily other crude oil for ANS crude.(15) Economic theory teaches that the ability to practice price discrimination is limited to firms that have market power.(16) As crude oil is the major input into gasoline, preserving competition upstream directly affects retail competition. The Commission and the Attorneys General filed lawsuits to block the merger in federal district court, and the case was settled with divestiture of all of ARCO's Alaska assets, including oil and gas interests, tankers, pipeline interests (in the Trans-Alaska Pipeline), real estate exploration data and selected long-term supply agreements. Those assets, now owned by Phillips, are currently the major supplier to the Puget Sound refineries, which are the primary suppliers of gasoline to the States of Oregon and Washington. Much of BP's ANS crude oil is now used in the former ARCO refineries in Los Angeles and Puget Sound, thus eliminating BP as the dominant supplier of ANS crude to other West Coast refineries. By combining BP's ANS production with ARCO's refining capacity, the Commission's Order reduces BP's incentive to elevate the price of ANS crude. By divesting ARCO's Alaska assets to Phillips, the Order retains an independent competitive force with the incentive to find and deliver additional ANS crude oil. IV. Conclusion By strictly enforcing the prohibition against mergers where the effect of the merger "may be substantially to lessen competition, or to tend to create a monopoly,"(17) the antitrust agencies ensure that already concentrated markets do not become more so. By challenging the Shell/Texaco joint venture and BP's acquisition of ARCO, the Commission helped preserve competition in several West Coast markets, both wholesale and retail. Requiring the divestiture of Shell's Anacortes refinery preserved competition in the supply of refined products to Washington and Oregon. Requiring the divestiture of ARCO's Alaska assets to a rival company (Phillips), prevented BP from enhancing its dominant position in the market to supply ANS to West Coast refineries. Endnotes: 1. This written statement represents the views of the Commission. My oral responses to questions are my own, and are not necessarily those of the Commission or any other Commissioner. 2. 15 U.S.C. § § 41-58. 3. 15 U.S.C. § § 12-27. 4. 15 U.S.C. § 18. 5. 16 C.F.R. Parts 801, 802, and 803, Premerger Notification: Reporting and Waiting Period Requirements for Certain Mergers and Acquisitions: Implementation of Recent Amendments to the Clayton Act (Jan. 25, 2001). 6. Under the Commission's shared jurisdiction with the Justice Department, antitrust investigations are allocated to one of the agencies under a long-established clearance procedure, based on expertise gained over the years in various industries. The Commission has expertise in oil mergers. 7. Section 7 of the Clayton Act specifically prohibits acquisitions where the anticompetitive acts affect "commerce in any section of the country." 15 U.S.C. § 18. 8. Industries might also consolidate for procompetitive or competitively neutral reasons, such as increasing scale efficiencies or a secular decrease in demand. 9. British Petroleum Company p.l.c., C-3868 (April 19, 1999) (consent order), Analysis to Aid Public Comment. 10. See United States Department of Justice and Federal Trade Commission, Horizontal Merger Guidelines § 4 (1992), reprinted in Trade Reg. Rep. (CCH) ¶ 13,104 (1992). 11. Exxon Corp., C-3907 (Nov. 30, 1999) (consent order). 12. British Petroleum Company p.l.c. , C-3868 (April 19, 1999) (consent order). 13. Shell Oil Co., C-3803 (April 21, 1998) (consent order). 14. Federal Trade Commission v. BP Amoco PLC, Civ. Action No. C00 0420-SI (N.D. Cal. 2000). 15. More complex refineries are usually better able to substitute different types of crude oil in their production mix. The Puget Sound refineries that serve Oregon and Washington are less complex than others on the West Coast. 16. As Judge Posner has noted, "price discrimination implies market power, that is, the power to charge a price above cost . . . without losing so much business so fast to competitors that the price is unsustainable." In re Brand Name Prescription Drugs Antitrust Litigation, 186 F.3d 781, 786 (7th Cir 1999). 17. 15 U.S.C. § 18. |


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Re: Date Sheet AIOU Spring
You want Allama Iqbal Open University BA course Spring date sheet so its date sheet still not published yet. As on 25 August 2012 on AIOU official website there are autumn 2011 date sheet available for following courses: ATTC , PTC, CT, B.Ed Matric & Post Graduate Programs FA, BA, Open-Tech Programs F.Sc. Practical Whenever BA Spring date sheet will publish we will provide you. |
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Mon, Jun 02, 2008
The hits just keep on coming... as Aero-TV is pleased to present another intriguing interview from the floor of the recently concluded AEA 2008 Annual Convention. During the latter part of this busy event, ANN's Jim Campbell was able to corner Ric Peri, AEA Vice President Of Government & Industry Affairs, in order to get some into the state of the avionics industry... from where he works in Washington, D.C.
Despite the many issues and challenges this industry faces, Peri remains upbeat about the future of the avionics industry as well as all of aviation. Still; Peri discussed his concerns and ideas about a number of topics... repair stations, third-party maintenance, the FAA including some GOOD things its doing at the moment), changes in field approvals, the Part 145 re-write, recent media reports about government supervision of the aviation industry, Re-Authorization and ADSB... and more!
The Aircraft Electronics Association represents more than 1,300 aviation businesses, including repair stations that specialize in maintenance, repair and installation of avionics and electronic systems in general aviation aircraft.
AEA membership also includes instruments facilities, manufacturers of avionics equipment, instrument manufacturers, airframe manufacturers, test equipment manufacturers, major distributors, and educational institutions.
OK, folks, here we go... we are NOW initiating the first feature programming series for Aero-TV... we're going to take it slow, but we're also going to try and be steady about this. DO UNDERSTAND that this is the most complex media program we've ever undertaken and what you're seeing is just the tip of the iceberg... but from here on out, we will be doing our best to educate, inform, and entertain YOU about all aspects of the exciting worlds of aviation and aerospace.
If you've been an observer of the media and associated media industries over the last few years, it's not hard to mistake the fact that a massive revolution is taking place. Old sources for news and information are falling by the wayside, having to change their modus operandi or risk obsolescence (or extinction). Electronic media and print media are both under the assault of progress, and the online world has been a cornerstone for revolutionary change.
We've been ready to go for a while, but to be honest, there's so much more to this program than we've alluded to, and so we've been building and planning a massive new organization within ANN. That said, we're hiring talented new people as fast as we can find them (a far more difficult task than we had imagined -- REALLY good people are hard to find), and we're brainstorming at speeds that would make a deorbiting Space Shuttle feel like a slug. Suffice it to say that we wanted to do this right, rather than right-now, and that the development of this program has been the most carefully pursued undertaking we've ever undertaken.
E-I-C Note: The complete feature shown above is embedded in this story, with most of the slick and useful functionality otherwise available on the main Aero-TV site (which will be upgraded aggressively over the next few weeks). The ability to embed a video on another web page is but one of the hundreds of amazing little features that we've worked hard on, for many months now, to implement in different phases of the initial release of Aero-TV. It is, BY NO MEANS, the only way to enjoy unaltered Aero-TV programming on other parts of the web... as we have extensive plans for future functionality, but this feature allows those with an interest in a specific Aero-TV News or Feature program to embed it on a different web site, though we must note that we reserve the right to forbid such use for those sites or purposes that we do not feel fit in with the proper mission of the Aero-News Network, Inc.
Webmasters or Administrators of well-trafficked aviation or aerospace related sites, are welcome to contact the Publisher to start conversations on how they may be able to leverage some of the immense power of Aero-TV programming for their sites and constituency by clicking the I Want Aero-TV For MY Website! link.
Aero-TV Presents An EXTENSIVE Look At All The Wonders of the 2008 AEA Convention, Takes A FLIGHT Under GARMIN SVT Guidance and Comes Away Amazed!, And Takes A GOOD Look At Honeywell's KFD840 and KNS770!, Checking Out the Cirrus SR20, Seeing What It Takes to "Compete" As An AMT, Looks At The FAA FAASTeam Program, Updates On The Garmin 495, Flying The Piper Matrix, Hears What's Hot At Blue Mountain Avionics, Gets Some GREAT Rotax Lessons, Gets Updated On ALL Things Lopresti, Has A FUN Chat With Corkey Fornof, Sees What Happens When AMTs Compete, Checks Out The Latest in Life-Raft Technologies, Checks Out More "HIGH" Tech at I/ITSEC 2007, Hears From AOPA On Critical Aviation Issues, Spills Some Juicy (and HIGHLY Detailed) Cirrus G3 Info, Scores A BUNCH of LSA Reports, and SO MUCH MORE!!!!! Do NOT Miss Them!
Airborne 12.06.13: EAA Meets FAA--In Court, Shell's UnLeaded AvGas, Jet WACO!
Aero-TV: Power Flow Systems - An Altogether Different Tune
Aero-TV: Michael Goulian -- Moving Airshows Forward In 2014
See All
New Online Resources Targe Published: Thu, Dec 05 2013
The Small Airplane Revital Published: Mon, Dec 02 2013
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Sotheby's London presents a rare and important offering of Old Master and British paintings
Pieter Brueghel the Younger, The Battle Between Carnival and Lent. Oil on oak panel. Estimate: £4-6 million / 4.9-7.4 million / $6.4-9.6 million. Photo: Sotheby's.
London will present an outstanding selection of rare and important masterpieces in its Old Master and British Paintings Evening Sale on July 4th 2012. The sale will, notably, feature no less than three large paintings by Pieter Brueghel the Younger, led by the monumental Battle between Carnival and Lent, one of his most accomplished works. Other highlights include two early 16th century masterpieces of the German Renaissance - Lucas Cranach the Elders Feilitzsch Altarpiece and Hans Baldung Griens jewel-like Virgin as Queen of Heaven - as well as Guido Renis monumental David with the Head of Goliath. The sale comprises 44 works with a combined estimate in excess of £26 million.
Alex Bell, Sothebys Co-Chairman and Head of Old Master Paintings Worldwide commented: This is a particularly rich and varied sale, offering collectors the opportunity to acquire some extraordinarily rare works. Lucas Cranach the Elders Feilitzsch Altarpiece is the last intact multi-panelled altarpiece by Cranach left in private ownership and comes to auction with a sparkling provenance we can trace back to its commission in 1511. The sale features some superb works from the Dutch Golden Age, a spectacular pair of Venetian vedute by Francesco Guardi which have been unseen for over a century and Guido Renis David with the head of Goliath, acquired directly from the artist in 1633 by the Duke of Modena.
Pieter Brueghel the Youngers The Battle Between Carnival and Lent, estimated at £4-6 million, is the artists most accomplished work to come to the market in recent memory. Depicting one of the greatest Breughelian themes, the work is a semi encyclopaedic exploration of the folklore and customs associated with the Shrovetide festival and the contrasts and contradictions of human nature. The composition is derived from the celebrated painting of 1559 by Pieter Bruegel the Elder in the Kunsthistorisches Museum in Vienna. This is the finest of five versions of the subject by Brueghel the Younger but the exceptional state of preservation of this early painting on panel, singles it out as the finest.
The Tower of Babel, estimated at £2-3 million is another of the artists most monumental and imposing works. Dating from the 16th century, this is one of his earliest works and one of his rarest subjects, known only in this, and one other painting. The superb condition of Saint John the Baptist Preaching to the Masses in the Wilderness, circa 1607, marks it out as the finest of all his treatments of this theme. Estimated at £1-1.5 million, the extraordinary survival of its pigments allows us a unique glimpse into Brueghels original glittering interplay of primary colours. All three works are from private collections.
Lucas Cranach the Elders Feilitzsch Altarpiece was almost certainly commissioned in 1511 by the sons of Jobst von Feilitzsch (depicted as the donor figure in the left panel) in their fathers memory. Estimated to realise £4-6 million, there can be few works of art which trumpet so proudly the fully-fledged Renaissance in Germany. The altarpiece which depicts some of the greatest examples of Cranachs portraiture, lends new understanding to the artists practices at a key moment in his career, when he was creating his most vivid and brilliant masterpieces at the court of Saxony. The work has belonged to only three families in its 500-year-old history, which may account for its extraordinary survival.
Appearing at auction for the first time in more than 30 years, another highlight of the German Renaissance is Hans Baldung Griens jewel-like panel depicting The Virgin as Queen of Heaven Suckling the Infant Christ estimated at £1-1.5 million. The work, by Albrecht Dürers foremost pupil was executed circa 1515-18, either at the end of Baldungs period in Freiburg or shortly after he returned to Strasbourg. The Virgins unusually large imperial crown features the Strasbourg lilies. The work is almost as notable for the extraordinarily beautiful under-drawing by the great draughtsman as it is for the sumptuous finish of its painted surface. The painting was previously in the collection of the Electors of Hohenzollern and Robert Von Hirsch, one of the greatest collectors of the 20th century.
Guido Renis dramatic David with the head of Goliath, acquired directly from the artist in 1633 by the Duke of Modena, is estimated at £3-5 million. The work, as much a towering monument to the Italian baroque as it is to Renis art itself, was executed at a pivotal moment in the artists stylistic development. An earlier version of the same subject by Reni is held in the collection of The Louvre. Previously considered lost, this intensely expressive work, discovered in 1985 in a private collection in Scotland, displays the looser brushwork and more subdued colour palette of Renis mature work in 1630s Bologna.
Depicting one of the key moments in Dutch naval history, Willem van de Velde the Youngers masterpiece The Surrender of the Royal Prince during the Four Days Battle, 1st-4th June 1666 is estimated at £1.52.5 million. Van de Velde the Younger, considered the greatest marine painter of the Dutch Golden Age, and his father, Van de Velde the Elder, were early war artists who went to extraordinary lengths to depict the battles raging in European waters, sailing alongside the Dutch fleets to sketch the warships in the heat of battle. This particular painting depicts the capture of the English flagship The Royal Prince during The Four Days Battle, fought off the coast of Flanders between the Dutch and English fleets in 1666. Van de Velde has, remarkably, depicted his father in a galliot, sketching the scene at the height of battle. The work was in the collection of Jan Gildemeester, who assembled one of the greatest collections of Dutch 17th Century paintings and drawings ever known. At his sale in 1800 the recently established Nationale Konstagllerij (predecessor of the Rijksmuseum) attempted to acquire the painting, which was even then considered a work of outstanding national importance. It has been owned by just three families in the ensuing two centuries.
Travellers Halted at a Country Inn is a rare collaborative work by the Ostade brothers, Adriaen and Isack (est. £1.8-2.5 million). With the landscape and most of the architecture attributable to Isack van Ostade and the large figure group in the foreground typical of Adriaen van Ostades work, this is most likely a unique example of the brothers working in collaboration. On grounds of style, this painting can be dated to the late 1640s, probably not long before Isacks untimely death in 1649.
The Evening Sale also comprises a pair of Venetian views by Francesco Guardi (est. £1.21.8 million): Venice, A View of the Entrance to the Grand Canal and Venice, A View of the Church of San Giorgio Maggiore. Beautiful as individual works, when the paintings are hung together they merge to form one expansive panorama of Venice, reaching across the Grand Canal from the island of San Giorgio Maggiore in the east, to the church of Santa Maria della Salute. These mature works, probably from the 1780s, are among Guardis best representations of this familiar scene. Part of the collection of a French noble family since the late 19th century, the pair come to auction for the first time in over a century.
A rare example of a painting by the 16th century Italian artist Orazio Borgianni, Christ Amongst the Doctors, is estimated to realise £400,000 - £600,000. Born in Rome in 1574, Borgianni, the son of a wood-painter, rose to become an artist favoured by the European aristocracy, naming some of the most powerful men in Rome among his patrons. Christ Amongst the Doctors has a remarkable early provenance. Listed in the inventory of the Spanish diplomat Juan de Lezcano in 1631, alongside at least eleven other works by Borgianni, the painting is believed to have been commissioned directly from the artist circa 1609.
*Estimates do not include buyers premium
Today's News
June 19, 2012
Exhibition at Museo Picasso Málaga provides a look at the history of the poster
Exhibition of drawings and watercolors spanning five centuries celebrates the collection of Joseph F. McCrindle
Sotheby's London to offer an extraordinary mid-14th century manuscript in the Welsh language
Archaeologist finds oldest rock art in Australia; an Aboriginal work created 28,000 years ago
Sotheby's London presents a rare and important offering of Old Master and British paintings
James Hyman to present specially curated exhibition for Masterpiece London
Garbage Guanabara Bay for Rio+20 from Brazilian-born, New York-based artist Vik Muniz
Rare look at the career of Regionalist painter Roger Medearis opens at the Huntington
Safani Gallery offers a rare anthropoid sarcophagus lid and coffin at Masterpiece London
Terra Foundation for American Art's new collections head selection evinces global goals
BALTIC Centre for Contemporary Art profiles commissioning legacy during 10th birthday season
Brilliant results for works by William Trost Richards and Jean Paul Riopelle at Keno Auctions sale
Former president of Capitol Records/EMI Joe Smith donates audio interviews to Librarian of Congress
Gettysburg on horseback takes riders back in time
Cult springs up around Hungary's World War II leader
Israel Museum exhibition sheds light on culture and life of Hasidic Jews
Black and White Spider Awards honors photographer Jack Dzamba from Boston
Lavish Mughal paintings embellish revised edition of The Imperial Image
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Native American masks sold in Paris to be returned to tribes by The Annenberg Foundation
National Gallery of Art presents The Dying Gaul: An ancient Roman masterpiece
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Remains of a 900 year old estate that has a fountain in its garden were exposed in Ramla
Robert L. Oswald, Brother of Lee Harvey Oswald Disputes Last Week's Sale of Coffin
Christie's Auction of Magnificent Jewels offers an Internally Flawless Golconda diamond
Marc Chagall work in German art trove was Nazi-looted: reports German tabloid Bild
$16 million gold Mao statue unveiled in China to commemorate his 120th anniversary
First exhibition to explore the impact in America of Sorolla opens at Meadows Museum
Christie's preliminary appraisal for City of Detroit delivered to the Emergency Manager of the City of Detroit
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- October 19, 2012
- 11:31 a.m.
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Atypicalife49 writes:
Guess you haven't driven down Jensen Beach Blvd lately to notice the 100 West signs, one every 30 to 40 yards a "No West" sign directly next to it.
Kind of hypocritical wouldn't you say?
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Author Archives: admin
Here & Now Production
What I have learned in the last 5 years is that quality takes time. About 6 months ago I began speaking with Kislay Mukherjee, a form PLU colleague who is currently working as a DBA at Amazon, about making a short film. Both … Continue reading
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Sorry, sleeping In.
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