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For fair use only. Published under the provision of U.S. Code, Title 17, section 107.
If you have any questions or would like to contribute and/or discuss the copyright status of one of these works, please contact me.
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A Coming of Age: Albania Under Enver Hoxha
by James S. O'Donnell
About this book
Though anti-communist, this book has a fairly controversial thesis that Hoxha provided rapid modernization that was only possible under the aegis of the communist regime. Albania Defiant
by Jan Myrdal and Gun Kessle
About this book
A left-wing Swedish view of communist Albania, mixing romantic history with contemporary (1969) observation and suffused with enthusiasm for the Hoxha regime and the Albanian people, regarded here as synonymous. The Swedish original appeared in 1970.
Amoral America: How the Rest of the World Learned to Hate America
by Robert W. Fearn
About this book
In 50 chapters, 750 pages and more than 500 pictures, this book tells the reader about American actions or policies that have created environmental disasters, poverty, illness, sadness and even death for millions of innocent people. Other books exist for virtually all of these issues but as far as we know, never in one book. American interventions in numerous countries as well as the overthrow of successful democracies are described in a readable, forthright manner. 'Amoral America' also discusses American government actions that have vigorously supported Weapons of Mass Destruction, Biological and Chemical Weapons, the Bombing of Civilians, Depleted Uranium, Global Warming, the War on Terror and weakening of the International Criminal Court, to name just a few. To foster this understanding and help create a more peaceful, prosperous and secure planet this book was written.
by Mamed Iskenderov
About this book
Published 1959, Part of a series on the SSRs, the fifteen Soviet Socialist republics.
In the early 1980s, the right-wing Reagan U.S. Government was determined to undermine or overthrow the leftist government of Nicaragua. As part of this campaign, the Central Intelligence Agency (CIA) produced a small illustrated booklet in both Spanish and English designed to destabilize the Nicaraguan Government and economic system.
by Bill Bland
About this book
Written in 1997 by Bill Bland, Class Struggles in China is about the Chinese state from 1949-1997, and how Maoist revisionism established a revisionist bourgeois regime from its very beginnings.
Economic Problems of Socialism in the USSR
By J.V. Stalin
About this book
Joseph Stalin's last major work before his death. This book would go on to be the economic blueprint of Socialist Albania.
by James Klugmann
About this book
A helpful guide to avoiding police and FBI repression.
Moscow Trial Transcripts 1938 (Full)
Programattic Proclaimation of the Soviet Revolutionary Bolsheviks
Spain: the Unfinished Revolution by Arthur H. Landis
Stalin's Speeches to CPUSA by J.V. Stalin
The Battle For China's Past: Mao and the Cultural Revolution Mobo Gao
The Facts About Soviet-Albanian Relations
The Soviet Union: Socialist or Social-Imperialist? Part I
The Stalin Constitution by I. Trainin
The Truth About Hungary Herbert Aptheker
About the book
A 1957 communist analysis of Hungarian Counter-revolution, weighing in at 256 pages.


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I was bottom of the class in science. Hated it. Went to art school to do something I loved. But my passion for fashion waned after several years on the unrewarding treadmill of commerciality. Now I find I've gone full circle - rediscovering radical creativity by engaging with science. An unconventional journey like so many other Tedsters I suspect...
designing from the bottom up, sustainable materials, future craft, style, artisanry, Mexico
We need to rethink future materials. As pressure on natural resources intensifies research is re-examining the use of microorganisms to produce fibres. Previously unable to compete with cheap oil-derived synthetics, cotton or even leather, bacterially produced cellulose has the potential to step up as a sustainable environmentally-friendly alternative.
Microorganisms can efficiently produce only what we need using waste streams for nutrient and biodegrade safely at end of life.
Advances in biotechnology enable us to imagine an optimised bacterium engineered to give us the exact performance qualities we desire. I'd like to say to a future bug, 'Spin me a thread, align it in this direction, make it hydrophobic and form this 3D shape'.
telling stories, how to have a conversation with a scientist, making beautiful things people will cherish, venturing into unknown territory, reinventing indigenous craft through contemporary design
continues...I'm thrilled to have been made a Senior Fellow and look forward to the new interactions this year will bring
TEDCred score: +152.30 TEDCred reflects your contribution to the TED community.
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Featured Business: Retrofit Home
First 10 people to spend $250+ at Retrofit Home, receive a pair of 3-day passes to CHBP 2013!
Seattle's modern home furnishings store featuring custom sofas, couches, rugs, pillows, lighting, jewelry, bags and wallets, wall art, greeting cards, books, design services and many other indescribably cool things that someone in your life is dying to receive~
When choosing your home furnishings, we believe that your choices should be an expression of your personality and lifestyle. Retrofit Home was founded with that belief in mind. Our goal is to provide high quality, unique, and affordable furniture that will last a lifetime. Retrofit Home specializes in contemporary home furnishings but have representations of Transitional and Mid-Century Modern styles as well. In addition to having furniture, paintings, and accessories, we also offer full design services. Our friendly and experienced staff can help you achieve the look that you have always wanted. Retrofit Home has designed and furnished numerous homes and models for the Seattle living community and we look forward to helping you achieve the home of your dreams.
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Mon – Wed: 11:00 am – 7:00 pmThu – Fri: 11:00 am – 10:00 pmSat: 12:00 pm – 10:00 pmSun: 12:00 pm – 5:00 pm


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- Mattel and Warner Bros. — apparently taking pity on the moviegoing audience — have reached a mutual decision to let the rights lapse to "Masters of the Universe," which Joel Silver had been developing for the studio with "Kung-Fu Panda" director John Stevenson attached to direct. Variety claims that Warners and the toy company "didn't see eye to eye over the direction of the project," and that Mattel hope to set the He-Man property up elsewhere, with Stevenson still on board, so we're not totally out of the woods yet, but at least it should be a few more years of development before this sure-to-be disaster hits the screen.
- Universal and Relativity Media have reached an agreement to release "Sanctum," the 3-D diving thriller that James Cameron is producing and Alister Grierson (Australian war movie "Kokoda") is directing. The picture, which sounds a bit like a damper version of "The Descent," will film later in the year in Australia, and be released at the end of 2010.
- Mandy Moore and Zachary Levi (TV's "Chuck") will lend their voices to Disney's 3-D animation "Rapunzel." Moore will play the titular long-haired princess, who escapes from her tower and goes on the run with a bandit (Levi). Ordinarily, we'd run for the hills from this, but "Bolt," the first post-Lasseter Disney animation, was pretty good, and Byron Howard, who was the co-director of that, returns here. The film also marks the return to Disney Animation of Alan Menken, composer of "Aladdin" and "Beauty and the Beast" (who did admittedly write the songs for "Enchanted").
- Finally, Collider have picked up the final trailer for the excellent-looking, and excellently reviewed, horror film "Trick 'r Treat." Like everyone else, we're baffled this is going straight to DVD (it hits October 6th) — surely Warners could market the shit out it of on the back of Anna Paquin's "True Blood" success, and history has shown that the teens of America will see pretty much any horror movie that's put in front of them...
Warners Does Us All A Favor And Dumps 'He-Man'; Mandy Moore To Let Her Hair Down As 'Rapunzel'
Posted by Oli Lyttelton at 8:55 AM
Labels: He-Man, James Cameron, Mandy Moore, Masters Of The Universe, Rapunzel, Sanctum, Trick R Treat, Zachary Levi
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text: The following agencies provide services for which sex offenders are eligible. Some of these agencies may accept sex offenders only on a case-by-case basis. Some agencies may operate programs which accept sex offenders while simultaneously operating other programs (for example: job training for day care employment) which do not accept sex offenders. It should also be noted that many of the organizations and agencies listed in the other sections of this Directory, do not exclude sex offenders; these should be contacted if they provide the type of assistance or service desired. |


text: The OEM Canon PG-210XL High Yield Black Inkjet Cartridge is available to you right on our site. The PG210XL is used in the MP240, MP480 & MX330 printers with Canon's new ChromaLife 100 System. This system, combined with fine printhead technology and select photo papers print out crisp images that are fade-resistant for up to 100 years when stored in an archival-quality photo album. Buy your Genuine PG-210XL and enjoy clear, accurate printouts from your Canon printers.


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A decent pace of technology news has returned, with this week's Bits & Bytes featuring a variety of worthwhile stories.
First, read Avoid Legacy Portfolio Software Constraints at Morningstar Advisor to learn how you can switch portfolio management software without incurring huge transition times or astronomical fees.
Here are this week's stories of interest:
The Rise of Robo-Advisors from Financial-Planning.com
[You are not clueless when it comes to the term "robo-advisors." (watch the two-part video, Competing Against "Robo Advisors:" Delivering Advice in a New World from T3 2012) Personal Capital, Wealthfront, LearnVest, and others have been highlighted here before, and Jonathan Leaf provides a new update in this Financial Planning magazine update.] Imagine being replaced by a robot. That day may be more imminent than many planners believe. In the past two years, a number of online financial platforms for investors have been launched. These sites offer computerized investment guidance aimed not only at the smallest customers, but also at those with upward of $250,000 in investable assets.
iRebal Receives Makeover from Financial Advisor magazine
[The last time I saw significant news concerning TD Ameritrade's iRebal software was back in August 2010 when RIABiz posted their overview of the product. This week, the growing custodian announced several enhancements to the stalwart application. I'm taking a look at the updates later this afternoon.] ThinkTech Inc., a TD Ameritrade affiliate, recently announced a number of major enhancements to iRebal, its highly-regarded intelligent rebalance and trade order management system.
Schwab Expands Practice Management Consulting Program for RIAs from Financial Advisor magazine
[Custodians continue to ramp up their value-add practice management resources as a competitive differentiator. In this update, Schwab Advisor Services announces new content for its nationwide traveling workshop.] Schwab Advisor Services today is expanding its "Insight to Action" practice management consulting program for its registered investment advisors customers that provides support on growing and managing their businesses.
Work aside; BACK UP your personal data including memories from InvestmentNews.com
[Here's another reminder how important it is to have a good backup routine and policy, not just for your business information, but your personal data, too. Details of Wired magazine contributor Mat Honan's loss of photos and other personal files as a result of a hack were syndicated across hundreds of websites this week. So take the prompt as a reminder to back up your files; something bad will eventually happen to your hard drive, so don't be without a plan. Me? I have a Time Capsule for my Mac.] Please back up your personal computers, especially photos and things of sentimental value, whether you use a Windows-based or Mac system.


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Camille C. Spencer.
Attention, foodies!
More than 85 food trucks from around the country are invited to participate in what's being billed as the "World's Largest Food Truck Rally" on Saturday, Aug. 31.
The event kicks off at 8:45 a.m. at Encore, an under-construction mixed use development at 1210 E. Ray Charles Boulevard, with food trucks departing at 9:15 a.m. to head to the Florida State Fairgrounds.
Once the trucks are at the fairgrounds, 4800 U.S. 301, the rally will run from 11 a.m. until 8 p.m. About 15 live bands will be in attendance.
The event is being sponsored by Generation Food Truck, Truckspotting.com and local food blog Carlos Eats.
Michael Lynch of Truckspotting.com, who is helping organize the rally, said the event has never been held in Tampa before.
"We live here, and wanted to show the world the amazing food talent that can be found in Tampa Bay," he said.
For more information on Encore, go towww.facebook.com/EncoreTampa, or go towww.encoretampa.com. For a full list of food trucks, go towww.greatfoodtruckfest.com. Parking at the fairgrounds is $6, according to the event's website.
Do you plan to go? Tell us in the comments.
This article was written by .
World's Largest Food Truck Rally Coming to Tampa Bay on Saturday
The world's largest food truck event is coming to the Tampa Bay area on Saturday, Aug. 31, so get ready for some good food!
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Jonsson T, Atwal JK, Steinberg S, Snædal J, Jonsson PV, Bjornsson S, Stefansson H, Sulem P, Gudbjartsson D, Maloney J, Hoyte K, Gustafson A, Liu Y, Lu Y, Bhangale T, Graham RR, Huttenlocher J, Bjornsdottir G, Andreassen OA, Jönsson EG, Palotie A, Behrens TW, Magnusson OT, Kong A, Thorsteinsdottir U, Watts RJ, Stefansson K. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature. 2012 Aug 2;488(7409):96-9. PubMed Abstract
This study only adds to the interest that my Alzheimer's Prevention Initiative (API) colleagues, other researchers, and I have in the possibility of evaluating suitable BACE1 inhibitors (and related agents) in persons at increased risk of developing AD, and our interest in learning more about safety, tolerability, and certain other effects in clinically affected patients. We see particular value in the possibility of evaluating anti-amyloid... Read more
This study only adds to the interest that my Alzheimer's Prevention Initiative (API) colleagues, other researchers, and I have in the possibility of evaluating suitable BACE1 inhibitors (and related agents) in persons at increased risk of developing AD, and our interest in learning more about safety, tolerability, and certain other effects in clinically affected patients. We see particular value in the possibility of evaluating anti-amyloid production treatments like these in ApoE4 carriers and young adult PS1 mutation carriers, since these agents might have the best chance to exert a profound benefit if started before the accumulation of significant fibrillar amyloid. View all comments by Eric M. Reiman
However, contrary to what is said by many, I do not think that the finding validates or... Read more
However, contrary to what is said by many, I do not think that the finding validates or confirms the amyloid cascade hypothesis. Reduction of β-processing of APP will first result in a reduction of sAPPβ and β-CTFs. Therefore, this finding is also consistent with alternative hypotheses of AD pathogenesis which point to sAPPβ and/or β-CTFs, and not Aβ, as the main pathogenic APP-derived metabolites (Tamayev et al., 2012; Nikolaev et al., 2009; Tamayev and D'Adamio, 2012). References:1. Tamayev R, Matsuda S, Arancio O, D'Adamio L (2012) β- but not gamma-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. EMBO Mol Med 4:171-179. Abstract
2. Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M (2009) APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 457:981-9. Abstract
3. Tamayev R, D'Adamio L (2012) Inhibition of gamma-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia. Mol Neurodegener 7:19. Abstract View all comments by Luciano D'Adamio
That the amyloid hypothesis inadequately accounts for the current data has been known for some time. It lacks a theoretical foundation from which the physiological generation of Aβ can be understood, and therapeutic approaches based on its premises have all failed. Furthermore, there is no significant correlation between Aβ accumulation and cognitive deterioration in either humans or in mouse models, and Aβ-containing senile plaques have been found in the brains of approximately 30 percent of individuals with no signs of dementia (Crystal et al., 1988; Price et al., 2009).
This does not necessarily indicate that Aβ is not a key factor in AD. The weakness of the amyloid hypothesis is not that it links Aβ and AD, but rather that it places Aβ as the key pathogenic trigger of the disease and, accordingly, ought... Read more
This does not necessarily indicate that Aβ is not a key factor in AD. The weakness of the amyloid hypothesis is not that it links Aβ and AD, but rather that it places Aβ as the key pathogenic trigger of the disease and, accordingly, ought to be the main target for therapeutic purposes. To date, all the available evidence—including clinical drug trials—indicates that this is an increasingly unlikely scenario.
Rather, the hypothesis that best fits the current body of evidence in the AD field, including the work by Jonsson et al., is that Aβ is a key element of the brain's adaptive response to stress. The idea of an adaptive response to stress in the brain, in the context of both aging and AD pathogenesis, has been put forward in various forms by scientists including George Perry, Mark Smith, Karl Herrup, and others (Stranahan et al., 2011; Stranahan and Mattson, 2012; Nunomura et al., 2001; Pappolla et al., 2002; Castellani et al., 2009; Herrup, 2010; Castello and Soriano, 2012). The idea is that failure of this adaptive response, or its chronic activation, is what leads to sporadic AD, instead of overproduction of Aβ itself. The nature of that stress in the brain is wide ranging, encompassing microglia activation, accumulation of reactive oxygen species, and cholesterol dysregulation, and the adaptive response it elicits involves regulation of APP through its cleavage products, including Aβ and sAPPα (Castello and Soriano, 2012; Stranahan and Mattson, 2012; Castellani et al., 2009).
In the case of the A673T mutation, all other factors being comparable, the combination of lesser Aβ levels, changes in APP-driven cholesterol regulation, and/or higher levels of sAPPα would all result in a more efficient adaptive response, accounting for the delay in AD age of onset described by Jonsson et al. (Castello and Soriano, 2012). Note also that the A673T mutation, creating a stronger adaptive response, is also consistent with the superior performance in cognitive tests of patients with the mutation. Mutation carriers retain cognitive ability for a longer period of time even when they do develop AD, as is visually demonstrated by the supplementary figures in Jonsson et al.
Overall, the message is that we should not rush back into the race to find the best BACE inhibitors to fight AD, as many commentators and scientists have suggested here and in the media. The line of inquiry involving BACE biology in AD has been in progress for over a decade, with negative outcomes, recent examples of which appear in the sidebar next to this very article (ARF related news story; ARF news story).
We need to reassess the way we approach research in the AD field. Instead of continuing a never-ending search for the elusive final proof that the amyloid hypothesis is correct, we should begin first by restructuring AD diagnosis to focus on symptomatic changes rather than the neuropathological identification of amyloid plaques, as has been suggested (Dubois et al., 2010). The pathological process of AD suggests variations of the same stress response. Therefore, our research should focus on the primary issue—the sources of stress that create a need for the adaptive response involving APP and Aβ. References:Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug;60(8):759-67. Abstract
Dubois B, Feldman HH, Jacova C, Cummings JL, Dekosky ST, Barberger-Gateau P, Delacourte A, Frisoni G, Fox NC, Galasko D, Gauthier S, Hampel H, Jicha GA, Meguro K, O'brien J, Pasquier F, Robert P, Rossor M, Salloway S, Sarazin M, de Souza LC, Stern Y, Visser PJ, Scheltens P. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol. 2010 Nov;9(11):1118-27. Abstract
Herrup K. Reimagining Alzheimer's disease--an age-based hypothesis. J Neurosci. 2010 Dec 15;30(50):16755-62. Abstract
Price JL, McKeel DW, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging. 2009 Jul;30(7):1026-36. Abstract
Stranahan AM, Cutler RG, Button C, Telljohann R, Mattson MP. Diet-induced elevations in serum cholesterol are associated with alterations in hippocampal lipid metabolism and increased oxidative stress. J Neurochem. 2011 Aug;118(4):611-5. Abstract
Stranahan AM, Mattson MP. Recruiting adaptive cellular stress responses for successful brain ageing. Nat Rev Neurosci. 2012 Mar;13(3):209-16. Abstract
Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis. 2009;18(2):447-52. Abstract
Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radic Biol Med. 2002 Jul 15;33(2):173-81. Abstract
Crystal H, Dickson D, Fuld P, Masur D, Scott R, Mehler M, Masdeu J, Kawas C, Aronson M, Wolfson L. Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology. 1988 Nov;38(11):1682-7. AbstractView all comments by Michael CastelloView all comments by Salvador SorianoView all comments by Matthew Zabel
It seems that amino acids at position 2 of hAβ with larger side chains than alanine may prevent aggregation. Di Fede showed that a transition, A2V, in Aβ was protective in heterozygotes, whereas homozygotic individuals had a higher risk in the studied family tree.
They also presented aggregation profiles of pure and mixed Aβ species that nicely supported the aggregation idea. Thus, the question remains whether it is indeed a BACE-related mechanism or just an aggregation problem of these Aβ species due to stereology. In our hands, cerebral injection and chronic infusion of A2V Aβ1-6 peptides reduced plaque formation in mice. That could be exploited as a treatment option (unpublished data).
As we know, mouse Aβ is different in three amino acids at the N-terminal, and these differences completely prevent plaque formation and fibril generation in mice. References:Di Fede G, Catania M, Morbin M, Rossi G, Suardi S, Mazzoleni G, Merlin M, Giovagnoli AR, Prioni S, Erbetta A, Falcone C, Gobbi M, Colombo L, Bastone A, Beeg M, Manzoni C, Francescucci B, Spagnoli A, Cantù L, Del Favero E, Levy E, Salmona M, Tagliavini F. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science. 2009 Mar 13;323(5920):1473-7. Abstract
Giaccone G, Morbin M, Moda F, Botta M, Mazzoleni G, Uggetti A, Catania M, Moro ML, Redaelli V, Spagnoli A, Rossi RS, Salmona M, Di Fede G, Tagliavini F. Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features. Acta Neuropathol. 2010 Dec;120(6):803-12. AbstractView all comments by Jens Pahnke
What gets ignored in ensuing discussions, however, is the fact that BACE processing of APP generates not only Aβ peptides, but also β-CTFs and AICD peptides (studies from three groups show that BACE processing enhances AICD generation and signaling [2-4]). Since both β-CTF and AICD cause AD-like pathological features in vivo in mouse models (5,6), the present study is consistent with, but cannot be claimed to support, the amyloid hypothesis (the causal role of Aβ in AD).
Nonetheless, this study is important because it identifies a unique human population (A673T carriers) that can be used to further validate neuroimaging (PIB imaging) and CSF biomarkers. Indeed, it will be very informative to see whether biomarker changes in this population appear at the same time as in the non-carriers or are... Read more
Nonetheless, this study is important because it identifies a unique human population (A673T carriers) that can be used to further validate neuroimaging (PIB imaging) and CSF biomarkers. Indeed, it will be very informative to see whether biomarker changes in this population appear at the same time as in the non-carriers or are significantly delayed. References:1. Zhao J, Fu Y, Yasvoina M, Shao P, Hitt B, O'Connor T, Logan S, Maus E, Citron M, Berry R, Binder L, Vassar R. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis. J Neurosci. 2007 Apr 4;27(14):3639-49. Abstract
2. Goodger ZV, Rajendran L, Trutzel A, Kohli BM, Nitsch RM, Konietzko U. Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway. J Cell Sci. 2009 Oct 15;122(Pt 20):3703-14. Abstract
3. Belyaev ND, Kellett KA, Beckett C, Makova NZ, Revett TJ, Nalivaeva NN, Hooper NM, Turner AJ. The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway. J Biol Chem. 2010 Dec 31;285(53):41443-54. Abstract
4. Tian Y, Crump CJ, Li YM. Dual role of alpha-secretase cleavage in the regulation of gamma-secretase activity for amyloid production. J Biol Chem. 2010 Oct 15;285(42):32549-56. Abstract
5. Berger-Sweeney J, McPhie DL, Arters JA, Greenan J, Oster-Granite ML, Neve RL. Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein. Brain Res Mol Brain Res. 1999 Mar 20;66(1-2):150-62. Abstract
6. Ghosal K, Vogt DL, Liang M, Shen Y, Lamb BT, Pimplikar SW. Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18367-72. AbstractView all comments by Sanjay W. Pimplikar
The latest flurry of results from pharmaceutical companies showing that BACE inhibitors reduce the levels of amyloid-β in the brain has led to a renewed wave of optimism that this approach may lead to an effective treatment for AD, possibly even a cure. This optimism has been amplified by the recent report of a mutation in the APP gene, A673T, that reduces BACE activity and protects against AD (Jonsson et al., 2012).
We have recently suggested that there is a plausible explanation for the effect of the APP A673T mutation on AD rates that goes beyond the conventional wisdom of "less Aβ protects, more Aβ harms" involving a fine-tuning effect on Aβ levels by the A673T mutation that improves the adaptive response of APP to AD-causing brain stress (Castello and Soriano, 2012). In other words, there is likely a range of Aβ that optimizes the adaptive response of APP to brain stress, and the A673T mutation helps to maintain Aβ levels within that range.
It is very unlikely... Read more
It is very unlikely that any laboratory-led BACE manipulation may result in a better therapeutic outcome than what this mutation provides. Indeed, a reduction in Aβ levels through BACE inhibition that is too dramatic would compromise Aβ physiological function and have a catastrophic impact on neuronal function, even if there were no fears of potential BACE side effects, which is also an unlikely scenario (see, e.g., note of caution by Weihong Song above).
Overall, everything we know very strongly suggests that inhibiting BACE activity in the brain to treat AD may not be the most sensible way forward. References:Jonsson et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature. 2000;488 ;96–99. Abstract
Castello MA, Soriano S. Rational heterodoxy: Cholesterol reformation of the amyloid doctrine. Ageing Res Rev. 2012 Jul 6. Abstract View all comments by Michael CastelloView all comments by Salvador SorianoView all comments by Matthew Zabel
However, another BACE1 inhibitor, minocycline, which is also neuroprotective and is already an approved therapeutic agent, is now undergoing trials in cognitively normal individuals and patients with mild cognitive impairment (MCI) or Alzheimer's disease (AD) at Huntington Medical Research Institute. Patients and controls will undergo clinical screening, neuropsychological tests, blood and urine analyses, quantitative magnetic resonance imaging (MRI), and 1H and 13C magnetic resonance spectroscopy (MRS). Each individual will receive minocycline oral administration for four weeks initially, after which MRI, MRS, and neuropsych results will be recorded. If no adverse side effects occur, subjects will continue minocycline administration for an additional five months.
A study by Ferretti demonstrated recently that minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE1 in a transgenic model of Alzheimer's... Read more
A study by Ferretti demonstrated recently that minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE1 in a transgenic model of Alzheimer's disease-like amyloid pathology (Ferretti et al., 2012).
There are a small group of Alzforum members who are interested in the emerging role of pathogens in Alzheimer's disease, and feel that β amyloid clearance problems may be the result of pathogenic inflammation (spirochetal) with and without viruses.
Chronic spirochetal infection can cause slowly progressive dementia, cortical atrophy, and amyloid deposition in the atrophic form of general paresis. There is a significant association between Alzheimer's disease (AD) and various types of spirochetes (including the periodontal pathogen Treponemas and Borrelia burgdorferi), and other pathogens such as Chlamydophyla pneumoniae and herpes simplex virus type 1 (Miklossy, 2011). Miklossy's lab at the University Medical School (CHUV), Lausanne, Switzerland, exposed mammalian glia and neuronal cells in vitro to Borrelia burgdorferi spirochetes and bacterial lipopolysaccharides. Morphological changes analogous to amyloid deposits were observed at two to eight weeks' exposure. Increased levels of β amyloid precursor protein and hyperphosphorylated tau were detected by Western blot (Miklossy et al., 2004).
Seven out of 10 brains from the Harvard McLean Brain Bank were positive for Borrelia DNA. Alan MacDonald demonstrated this, and feels "Borrelia burgdorferi infection is the root cause of at least 70 percent of Alzheimer's disease, based on the detection of positive in-situ DNA hybridization results in the cytoplasmic granulovacuolar bodies of hippocampal neurons (with no positive signals detected in the nucleus) for flagellin B DNA sequences of Borrelia burgdorferi" (MacDonald, 2007).
A randomized controlled trial of doxycycline and rifampin for patients with Alzheimer's disease demonstrated that cognitive decline was statistically improved in the treatment arm over placebo (Loeb et al., 2004).
Minocycline protected basal forebrain cholinergic neurons from murine-p75-saporin immunotoxic lesioning in animal models (Hunter et al., 2004). Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models (Choi et al., 2007). Minocycline does not affect amyloid-β phagocytosis by human microglia cells. Minocycline attenuates the release of TNF-α by human microglia upon exposure to Aβ, SAP, and C1q (Familian et al., 2007).
Moderate magnetic field therapy (0.5 Tesla) in 15 Alzheimer's patients was demonstrated by this author in 2006 on the hypothesis that the outer protein of the Borrelia burgdorferi bacteria is strongly electron-negatively charged and will be repelled by the negative pole of a 0.5 Tesla electromagnet below and a positive pole above the patient's head. Cognition improved. However, this improvement was gradually lost from several weeks to six months in these patients in an open-label, IRB-approved pilot study. All patients had moderate to severe Alzheimer's disease (Nichols et al., 2006).
The mechanism may also be related to crosstalk between SMF and IL-6, as well as the upregulation or downregulation of over 2,600 genes (Wang et al., 2009). References:Ferretti MT, Allard S, Partridge V, Ducatenzeiler A, Cuello AC. Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology. J Neuroinflammation. 2012;9:62. Abstract
Miklossy J. Emerging roles of pathogens in Alzheimer disease. Expert Rev Mol Med. 2011;13:e30. Abstract
Miklossy J, Khalili K, Gern L, Ericson RL, Darekar P, Bolle L, Hurlimann J, Paster BJ. Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease. J Alzheimers Dis. 2004 Dec;6(6):639-49; discussion 673-81. Abstract
MacDonald AB. Alzheimer's neuroborreliosis with trans-synaptic spread of infection and neurofibrillary tangles derived from intraneuronal spirochetes. Med Hypotheses. 2007;68(4):822-5. Abstract
Loeb MB, Molloy DW, Smieja M, Standish T, Goldsmith CH, Mahony J, Smith S, Borrie M, Decoteau E, Davidson W, McDougall A, Gnarpe J, O'DONNell M, Chernesky M. A randomized, controlled trial of doxycycline and rifampin for patients with Alzheimer's disease. J Am Geriatr Soc. 2004 Mar;52(3):381-7. Abstract
Hunter CL, Quintero EM, Gilstrap L, Bhat NR, Granholm AC. Minocycline protects basal forebrain cholinergic neurons from mu p75-saporin immunotoxic lesioning. Eur J Neurosci. 2004 Jun;19(12):3305-16. Abstract
Choi Y, Kim HS, Shin KY, Kim EM, Kim M, Kim HS, Park CH, Jeong YH, Yoo J, Lee JP, Chang KA, Kim S, Suh YH. Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models. Neuropsychopharmacology. 2007 Nov;32(11):2393-404. Abstract
Familian A, Eikelenboom P, Veerhuis R. Minocycline does not affect amyloid beta phagocytosis by human microglial cells. Neurosci Lett. 2007 Apr 6;416(1):87-91. Abstract
Nichols et al. Medical Hypothesis; elctromagnetic field therapy using Magnetic Molecular Energising (MME) and Antibiotic Therapy: A Pilot Study. 31/01/2006. E pub; European Biology and Bioelectromagnetics.
Wang Z, Sarje A, Che PL, Yarema KJ. Moderate strength (0.23-0.28 T) static magnetic fields (SMF) modulate signaling and differentiation in human embryonic cells. BMC Genomics. 2009;10:356. AbstractView all comments by Trent Nichols
PRIMARY NEWSProtective APP Mutation Found—Supports Amyloid Hypothesis
RELATED NEWSWave of New BACE Inhibitors Heading to Phase 2Scientists Hunting Rare Alzheimer's Mutations Eye Phospholipase D3


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Chris Pulman and Gerard Watts on The Skateboarding Show.
Brett's got two new installments of The Skateboarding Show currently ready for your ears, the first featuring an interview with Gerard Watts of Ekta Skateboards, the second revolving around an interview with Chris Pulman, focusing mainly on Slam City Skates and their first full length video project "City of Rats".
Listen away below…
Gerard Watts/Ekta:
The Skateboarding Show, 7 March 2012: EKTA Skateboards by theskateboardingshow
Chris Pulman/Slam City:
The Skateboarding Show, 14 March 2012: Chris Pulman by theskateboardingshow


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Stuhrling Original Women's Lifestyle Collection Courtly Passion Diamond Swiss Quartz Watch
Switzerland was emerged as the global leader in watchmaking in the 1800′s and till today they have maintain their heritage with dedication and commitment. Stuhrling Original is following that commitment and heritage as a mission to preserve Switzerland manufacturing in their Swiss owned factory by setting those high standards. Every single Model of Stuhrling Original conveys an inimitable story with extra ordinary style. Every watch collector will cherish and admire the huge and fascinating collection for men and women.
The sparkling diamond accented dial add extra elegance to the Stuhrling Original Women's Romance Collection Courtly Passion Diamond Swiss Quartz Watch. The square case features smooth rounded corners and is made of the finest grade stainless steel, 316L. A Guilloche designed dial beautifully displays Arabic numerals at the three, six, and 12 o'clock hours. A diamond and beadwork heart sparkles at the center of the dial. A date window is displayed near the seven o'clock position with a heart shaped magnification bubble on the shatter-resistant Krysterna crystal. The alligator embossed genuine leather band adjusts to fit comfortably and fastens securely with a buckle clasp. This Stuhrling Original timepiece offers reliable Swiss quartz movement and is water resistant to a depth of 165 feet (50 meters).
Categories: Women Watchs Tags: classic watch, romance collection watches, women watch
Stuhrling Classic Delphi Omega Rose Gold Watch has Its Own Gravitational Field
The Delphi Stührling classic Omega Watch Gold Rose is beautifully designed. Skeleton Watch features cutaways that give you or admirers to see the inside of the clock. The back also includes a front glass to look through watch. The display is very readable – in part because the thing is huge! It looks great in photos of products, but they do not do justice…
This thing is great. I mean, really big. It looks something according to Sean Bradley and Andre the Giant. It is so great, that has its own gravitational field! Have you seen the Irish Spring soap commercial? Imagine the kind saying, "Look at your watch. Now look at mine. Again, look at yours and mine. Your watch looks like a microscopic miniature next to my Stuhrling…" The diameter of the clock is a full inch and 3 / 4 inEcuador, about 150% the size of a man could be used to carry on the wrist. No need to carry the weight when you have a Stuhrling a doll. Do not even need to move the weight, only to compensate for the unequal distribution will give the desired performance.
But do not let size deter you. I thought it actually works for the proportions of a pocket watch. I mounted mine on a belt fob and it shows beautifully that way. Several people commented on the complex design. If I can upload a picture to customers, you will see that this is a nice setting. It's really a cool show.
Categories: Classical Watches, Mens Watch Tags: classic watch, men's watch, stuhrling, stuhrling original


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Tipard iPhone 4S Transfer, the most powerful and multi-functional iPhone 4S transfer, own the professional transferring function which can help you transfer various files between iPhone 4S and your computer. In addition, this transfer owns another fantastic function, which can easily rip any DVD movies and convert video files to iPhone 4S supported files. Plus, you can also edit the video before converting and importing it to your iPhone 4S, and it highly supports the newest iOS 5.0.1 and iTunes 10.5. Key Features: 1.Transfer files between iPhone 4S and your computer Tipard iPhone 4S Transfer provides you with the powerful transferring function which iTunes does not have. Tipard iPhone 4S transfer enables you to transfer various files between your iPhone 4S and computer without any restriction and limitation. 2.Highly supports iPhone 4S and all other Apple devices Support iPhone 4S, iPhone 4, iPhone, iPhone 3G and iPhone 3GS; iPad Wi-Fi, iPad Wi-Fi+3G, iPad 16GB, iPad 32GB, iPad 64GB; iPod 1G, iPod 2G, iPod 3G, iPod 4G, iPod classic, iPod mini, iPod nano 1, iPod nano 2, iPod nano 3, iPod nano 4, iPod nano 5, iPod nano 6, iPod shuffle 1, iPod shuffle 2, iPod shuffle 3, iPod touch, iPod touch 2, iPod touch 4, iPod Video, iPod Firmware 3.0/3.1. 3.Perfectly compatible with many file types With Tipard iPhone 4S Transfer, you can easily transfer many popular media files, including music/movie/Pictures/Camera Roll/Ringtone/Voice memos. 4.Three file sorts for you to choose This iPhone 4S transfer provides Artist, Album and Genres file sorts for you to choose. You can select any one to sort the file according to your favorite. 5.My Cache function With this function, you do not need to keep your iPhone 4S connecting to PC while this iPhone 4S transfer converting unsupported file to iPhone 4S compatible format. My Cache function can save the output file on PC for your later use.
Platform:Windows 2000, Windows XP
System Requirements: 800MHz Intel or AMD CPU, or above; 512MB RAM or more


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Dear Customers,
Herewith you receive the latest SOFiSTiK Newsletter 06/2012.
For any questions or feedback simply write us an email to email@example.com. Older issues can be viewed through our news archive. We will publish this newsletter (as well as other news/events) also through a RSS-feed:
Best regards, your
The hyperlinks are optimized for Mozilla Firefox (Opera, Chrome etc. work as well). In Internet Explorer, there are known problems of interpretation.
New Servicepacks available
There are new versions and servicepacks for the SOFiSTiK FEA Version 2010 and 2012, SOFiPLUS(-X) and SOFiCAD available for update via SONAR. Detailed info about each program´s changes can be obtained from the LOG-files.
SONAR offers a nice feature to let you read the difference of your local and the latest log-file on the server before you press the update-button! If you select the manual update, you can use the right-mouse click (Step 3 in SONAR update) on one module in the module list and select "Show change-log".
We will publish the change log through a RSS-Feed as well. Subscribe to the feed and get an automatic email once there is a new (hotfix-) version of a program.
Feed-URL FEA log-files:
Version 2010: http://feeds.feedburner.com/sofistiklog-en
Version 2012: http://feeds.feedburner.com/sofistik2012logen
Feed-URL SOFiCAD log-files:
Version 2010: http://feeds.feedburner.com/soficadlog-en
Version 2012: http://feeds.feedburner.com/soficad2012logen
New Installations with FEA Extensions for Revit® 2013 available
As the SOFiSTiK FEA Extensions for Revit Structure are now released for Revit 2013 (32 and 64-Bit) new installation packages have been made available for download. To add the necessary FEA Extension to your existing installation, please download and run the installation and choose 'Add or Remove Feature'.
Installation SOFiSTiK FEA 2012 excl. SOFiPLUS-X (32/64-Bit,.exe/approx. 330MB)
Installation SOFiSTiK FEA 2012 incl. SOFiPLUS-X (32/64-Bit,.exe/approx. 1.3GB)
A new module DOLFYN has been released with servicepack 06/2012. SOFiSTiK is now supporting an open-source CFD program (www.dolfyn.net) and offers full integration with SOFiSTiK environment. Specifically:
- Mesh generation with SOFIMSHA/SOFIMSHC
- Automatic tetrahedral meshing (NETGEN)
- Post-processing with WinGRAF
- Full CADINP support including formulas for boundary and initial conditions
- Easy wind definition (atmospheric boundary layer) directly or via SOFiLOAD
- Standard wind profiles with turbulence parameters according to EN 1991-4, SIA,
- Direct generation of resulting wind loading in the data base
More information about DOLFYN and CFD can be found here.
For any questions please contact: firstname.lastname@example.com
SOFiSTiK Reinforcement for Autodesk® Revit® 2013 Preview Version available
We would like to inform that a preview version of SOFiSTiK Reinforcement for Autodesk® Revit® 2013 is now available.
You can register here in order to download it (Prerequisite: Revit Structure 2013 64Bit).
More information and a video about the workflow, could be found here.
Download Video: 'New Features 2012 SOFinar'
In order to introduce the features of the 2012 release together with some improvements of servicepack 4 a SOFinar has been held in March. For those of you who have not been able to watch it live, a video is available in the Infoportal.


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2011-10-17 12:10:00
The first Hockey News player of the week for the 2011-12 season is Phil Kessel of the Toronto Maple Leafs.
Over the first 11 days of the season, Kessel has been off to the races.
In Toronto's season-opener against Montreal Kessel got 20:50 of ice time and managed a lone assist and a plus-1 rating in the 2-0 victory.
Two nights later in a wild 6-5 win over Ottawa, Kessel notched a hat trick and added an assist for a four-point night in 19:43 of ice. He recorded his first power play point of the season and also registered the game-winning goal.
Kessel's third game didn't come until a week later when the Leafs hosted the Flames. Despite the layoff, Kessel was still sharp, recording two goals and an assist in a 3-2 win. The fifth overall pick from 2006 scored his second game-winner of the season as the Maple Leafs are off to a surprising 3-0-0 start.
With five goals and eight points in three games, Kessel is tied with John Tavares and David Legwand for the early lead in NHL scoring.
This Week - Subscribe NowWho will win the Stanley Cup?
"I think it was deserving of a two minute penalty. I'm being honest here, I don't think it was more than that. It was probably the way he went into the boards that did most of the damage, not from the severity of the hit."
- Boston Bruins coach Claude Julien on Canadiens forward Max Pacioretty's hit against Bruins defender Johnny Boychuk Thursday night.


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People Who Went To Penn: Matt Blank
Matt Blank W'72 (obviously, Matt LeBlanc's no-frills cousin) is the Chairman and CEO of Showtime, a position he's held since 1995. Blank hopped over to Showtime from HBO way back when and worked through the ranks, garnering positions like President and Chief Operating Officer in 1991 (piece o' cake), until he finally landed himself a spot as the network's top diggity dog.
A bunch of award-winning shows have "sprouted" under Blank's reign, including Weeds, Queer As Folk and the new BBC collaboration series Episodes (ah, and the Matt LeBlanc reference comes full circle).
Like any true Penn grad, Blank lives in NYC with his wife and kids, and is a big supporter of all things Jewish and gay. You can check out his exclusive advice on how to break into the TV industry on Wharton's site here.
Tags: Features, alum, alumni, ceo, hbo, matt blank, people who went to penn, showtime, tv industry, weeds, wharton
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Hello Doves,
First I'm very excited I have to tell all of you something. This
morning while getting ready for work it was like a large brick hit me
on the head for the reason I've been seeing 11's everywhere for the
past two years. I wrote down November 1, 2010 and it's the sets of
11's I've been seeing. Now, I don't know for certain, I'm just saying
I got the same feeling when God gave me the thug on who the antichrist
is. I started counting on the calender from Oct. 25th which I believe
is when Noah entered the ark. I'm not certain, I've been so stressed
on my job lately, I haven't gotten to read all the articles I wanted on
5 doves. I believe we will recieve a 7 day warning on the 25th of
October to enter that Ark. Seven days from the 25th is 01/11/10. Now
when I counted the 7 day warning I burst out laughing so hard I was in
tears. I was laughing so hard because on the calender I have at home
it says at the bottom that November 1st is "ALL SAINTS DAY". I was
like, Wow oh my gosh, our Lord does have a great sense of humor AND the
reason Obama is not worried about the elections is because sudden
destruction is going to happen right before. The world will be in such
complete social breakdown, government breakdown, chaos, that people
will not even realize the elections are suppose to happen.
I'm so excited I know I won't be able to sleep tonight. I'll just be
praising our Master Jesus Christ!!!
I can't wait to see all of you.
God Bless,
Tyra Marts


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Not Instead of, in Addition to
Friday, French Quarter Fest. Capital One Bank Riverside Legacy Stage.
I was not tired, I was not drunk or tipsy or giddy, I wasn't hungry or dehydrated or hot at all–I'd had three bottles of water, I had three fans in my bag I hadn't touched because the breeze off the river was steady enough and I had a visor and, until the stem broke because it'd been sat on, an umbrella. I did have a mild headache. A mild pulsing and buzz, a thickness in the back of my head. I thought I'd sat too close to the stage and may've been feeling overstimulated, another and irritating FM symptom. Nothing out of the ordinary hurt, which means everything that typically hurts hurt—neck, shoulder muscles, one hip and then the other, calf muscles, finger joints, soles of my feet. Standing, my lower back, hips and legs felt blurry, light and heavy at the same time. I took two steps, my legs feeling discoordinated, like where I aimed them to go was not exactly… Continue reading
What I Learn from I Survived
See I Survived…I Survived…I Survived…, July 1, 2011, for background.
1. For women: When a man threatens with a gun or knife and tells you to do what he says and he won't hurt you, he will hurt you whether you comply or not.
1A. "You won't get hurt" doesn't count rape, gang rape, or being beaten. It means, and only temporarily, that you will not be killed.
1B. Whether you resist or not, you have a 50% or so chance of surviving. You lose nothing by resisting or saying no, running or fighting with whatever you have.
1C. Begging for your life means nothing. If he wants to and has come to kill you, no appeal to humanity, not his and especially not yours, will change the course of events.
2. If you are taken away from your original location, it is unlikely that you will be returned to that location, alive or dead.
3. If you are lost in a blizzard or dangerous cold, eating snow may satisfy your thirst but it will… Continue reading
You Know Why
originally posted at The G Bitch Spot
John White appears poised to be named state schools superintendent this week
No surprise here. This has been wanted since 3 days after he became superintendent of RSD. [Even now, no one in public has asked, or questioned, why.] Now that the privatization forces have BESE in their front pockets, we in NO will have a completely privatized system.
Who voted for that, you might ask.
Problem is when schools like this get their charters pulled or denied. What happens is that the number of seats in city schools goes down, and charter schools are NOT obligated to take students whose schools close or implode.
And this new "systems" is better how exactly for whom?
Solution Meets Problem
crossposted at The G Bitch Spot
The solution:
The news racing around the shelter that day was that the Republican Congressman Richard Baker had told a group of lobbyists, "We finally cleaned up public housing in New Orleans. We couldn't do it, but God did." Joseph Canizaro, one of New Orleans' wealthiest developers, had just expressed a similar sentiment: "I think we have a clean sheet to start again. And with that clean sheet we have some very big opportunities."
Much of the media interest in the first anniversary of the onslaught of Hurricane Katrina in August fixated on the negative. Sometimes, however, hurricanes have silver linings: when Hurricane Katrina demolished New Orleans's public school system it gave the city's educational landscape a much-needed clean slate.
According a New York Times report, New Orleans public schools were "among the most abysmal in the nation before the storm". In the 2004 Louisiana General Exit Exams (GEE) for high school students, 96 per cent of New Orleans public school students scored… Continue reading


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skibum - 5:50 am on May 3, 2006 (gmt 0)
there is no real incentive to do anything about it and it's only the lawyers that win. They probably get cash, doubtful that the lawyers will also get paid in free clicks from Google for that one. It's like MSFT losing a lawsuit and giving the winning party a bunch of Microsoft software to satisy the judgement.
Somebody needs to file a suit like this and go for broke, no settlements. If the engines are able to settle and get away with offering settlements like this: For all eligible invalid clicks, we will offer credits which can be used to purchase new advertising with Google. We do not know how many will apply and receive credits, but under the agreement, the total amount of credits, plus attorneys fees, will not exceed $90 million.


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It took a special species to rescue HBO from several years in the comedy doldrums, when most everything (except sporadic seasons of Curb Your Enthusiasm) felt overly precious or ironic and hardly ever funny.read more
Warrick's addiction to pills begins to impact his job when his investigation into the underground mob in Vegas results in him being targeted as the prime suspect in a mob-related murder case. watch
Jerry Ferro's (Adam Carolla) 40th birthday has brought his life into sharp relief and it's not a pretty picture. A once-promising amateur boxer -- who quit so he wouldn't risk his perfect record of underachievement -- Jerry has been knocking around from one construction job to another and spinning his wheels in an unsatisfying relationship, all the while with an eye toward eventually getting his shit together. His last connection to the fight game is the evening boxing class he teaches to middle-aged, middle class, middle management types at a gym in Pasadena, where he also works as a handyman. When venerable boxing coach Eddie Bell (Tom Quinn) asks Jerry if he'd like to spar a couple of rounds with Malice Blake (Harold House Moore), an up-and-coming pro, Jerry reluctantly steps into the ring. Despite the ass-kicking Jerry otherwise receives, a one-punch knockdown of Blake convinces Jerry that it s time to make his return to competitive boxing. Thus ends a 20-year layoff and begins a hilarious fish-out-water quest for Olympic gold.
more Harold "House" Moore Clips & Interviews videos
Jennifer Beals guest-stars as Assistant U.S. Attorney Zoe Landau, Lightman's ex-wife and Emily's mother. When she enlists Lightman to help investigate an arson case in which the only eyewitness is a 5-year-old boy, it quickly becomes clear that she and Lightman still have feelings for each other. Meanwhile, Foster and Torres question a rapper who is suspected of murder. Also available on Netflix, Amazon Prime, Amazon Instant Video and VUDU
Kiki's brother, Darnell, returns to the shop. Malik and Alex find a way around the 'no date' rule by having a date in Malik's back yard. Also available on Amazon Instant Video
Warrick's addiction to pills begins to impact his job when his investigation into the underground mob in Vegas results in him being targeted as the prime suspect in a mob-related murder case. Also available on Amazon Instant Video
A lifelong collector sells his prized possessions and Cari sets up a huge sale.
more Harold "House" Moore On TV videos
more Harold "House" Moore credits (4 total credits)


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A "study carrel" environment is a tried and true process to increase student focus" One of the small pleasures in life is to find a quiet spot, relax in a comfortable chair and read a book. There are those among us, however, that do not require the solitude or quiet. They can read in a busy airport or in a noisy restaurant. Chances are, most people have a preference about which environment they desire for maximum enjoyment of the written word. In a school setting, students should have the same choice. All students are familiar with the library and know the importance placed on "quiet" in this area. What may come as a surprise to educators is that librarians are privy to inside information about the environment within the library. The secret is this – study carrels. All public libraries and institutions of higher learning offer these quiet zone areas for reading and study. They spend large amounts of money to provide these individualized spaces because they are extremely effective for learning. Dr. Arthur W. Hafner, Dean of University Libraries at Ball State University, states, "Our libraries offer a large number of study tables and comfortable chairs throughout for both individual and collaborative study. Some are in large open spaces and surrounded by other study tables. Others are arranged in groups of two or three, and some carrels stand-alone for private or small group use. Informal questioning of students reveals that they enjoy studying, learning, and collaborating in an environment where others are doing the same." During a student's early years in kindergarten, elementary and middle school it is vital that they develop strong reading and language skills. Most libraries at these levels only offer large tables or desks, mostly due to budget constraints. ClassroomProducts.com has the solution with their inexpensive, portable study carrels. Kenny Kiskis from ClassroomProducts.com states, "Libraries have used study carrels for years knowing their capability of keeping noise levels down, and giving user's privacy and a better environment for focusing on their work." Regardless of the grade level, students should have study carrel spaces to read and learn. In the library setting this is particularly important to fostering a love of books and a feeling of success during the reading process. The study carrels offered by ClassroomProducts.com will match the needs of the learners and the budget of school. |
"Making Your Own Carrels?" "Click Here" to View or Print our Fact Sheet (.pdf document) |
All Rights Reserved © 2013 ClassroomProducts.com 1-800-315-0741 FAX (937) 342-1703 Classroom Products LLC 3101 Campbell Drive Springfield, Ohio 45503 |
State by State DOE Guidelines for Study Carrels |
Helpful Links |
This is great information to help you decide if you should make your own carrels. For help with "Choosing the Right Carrel" "Click Here" Feel free to contact us if you have any questions or concerns! To e-mail a copy of this worksheet to others, open the file, save to your computer, and attach to your e-mail. Print a Brochure! |
* Shipping Charge 10%, $6.95 Minimum for delivery to a school / office anywhere within the lower 48 U.S. States. For residential deliveries an additional $5.95 per carton delivery charge will be added ! |
Our 13" Desktop Carrel Compared to flimsy manila folders! |
Made in the U.S.A.! Affordable! Instant Testing Lab! Durable! Can Reduce Cheating! Easily stores flat! Professional Appearance! |
Making Your Own Carrels |
800-315-0741 |
(Fax) 937-342-1703 |
"Helping Students Focus" Since 2003 |
® |
Our American Made Products Normally Ship in 1 to 2 Days! |


text:
1990 Corvette ZR1 rare polo green metallic with Saddle Tan interior and is 1 of 104 produced that year. ZR1 motor LT5 configuration V8,... More
1990 Chevrolet Corvette Coupe for sale in Indianapolis! Built for the track but totally street legal this Corvette can get you to work Monday... More
1990 Corvette convertible. Red/ Red w/ blk canvas top, 6-speed, all working power accessories incl windows, locks, seat, mirrors(heated), good tires, 114K miles w/... More


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i dont see why it would make a difference... go for it
I am building a stealthy grow room and trying to do it on a budget. Its in the unfinished part of the basement and it would save money to do a gravel and stepping stone floor instead of concrete if possible.Dose anyone think the gravel and stepping stone floor would be OK ?
i dont see why it would make a difference... go for it
http://www.rollitup.org/general-mari...urnal-3-a.html weed will get you through times with no money better than money will get you through times with no weedmy new you tube video http://www.youtube.com/watch?v=7ZRc6Y9GUGI
i would put a tarp under the pots or else your going to have a lot of nute run off build up in the gravel floor and cause fungus and stink.you want to be able to keep it clean believe me.
set off a doctor doom bug bom fogger before you put any plants in there just in case !
Sounds good. Thank you for the advise.


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MannKind Corporation (Nasdaq: MNKD) is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutic products for patients with diseases such as diabetes.
Our lead investigational product candidate, AFREZZA® (pronounced uh-FREZZ-uh) is a novel, ultra rapid-acting mealtime insulin therapy. AFREZZA is in late stage clinical investigation for the treatment of adults with type 1 or type 2 diabetes for the control of hyperglycemia. It is a drug-device combination product, consisting of AFREZZA inhalation powder pre-metered into single use dose cartridges and the light, discreet and easy-to-use AFREZZA inhaler. Because of its unique pharmacokinetic profile, AFREZZA may be a promising new therapy for patients with Type 1 and Type 2 diabetes, as it controls post meal-time glucose levels with less weight gain and lower risk of hypoglycemia.
AFREZZA utilizes our proprietary Technosphere® formulation technology, which is based on a class of organic molecules that are designed to self-assemble into small particles onto which drug molecules can be loaded. We believe Technosphere represents a versatile drug delivery platform that may allow pulmonary administration of certain drugs that currently require administration by injection, such as GLP-1. Beyond convenience, we believe the key advantage of drugs inhaled as Technosphere formulations is that they have been shown to be absorbed very rapidly into the arterial circulation, essentially mimicking intra-arterial administration. MannKind is also developing other inhalation technologies, including an innovative line of patient-focused, breath-activated, dry powder inhalers and inhalation profiling to characterize patient inhalation.
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text:
All Star Sports
Start: Tuesday, November 6, 2012
Hingham , MA 02043
About This Activity
ALL STAR SPORTS Grades 1 & 2
Come for some fall fun! This program gives participants an opportunity to experience many different sports in a fun and safe environment. This is a 6 week class. Coordinator: Jen Manning


text: Can anyone tell me if Osunlade's Black Messiah mix of Midnight ceremony by boobjazz ever came out on a 12" and where I might get one if it did? i know about the midnight ceremony suite on dance wicked and the one night at shelter lp, but neither of these have the mix i need. I know it's on osunlade's 'offering' mix album, but I'd really like the 12"... Any help gratefully recieved!


text:
Browse our mobile site for the best experience on your device.
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Rhino Classic Albums Collection [f.y.e. Exclusive]
Original Release Date: November 27, 2009
Track Listing
1. Breaking the Chains
2. Paris Is Burning [Live]
3. Into the Fire
4. Just Got Lucky
5. Alone Again
6. Tooth and Nail
7. The Hunter
8. In My Dreams
9. It's Not Love
10. Dream Warriors
11. Burning Like a Flame
12. Heaven Sent
13. Mr. Scary
14. Walk Away
15. Mirror Mirror
16. Too High to Fly
17. Without Warning
18. Tooth and Nail
19. Just Got Lucky
20. Heartless Heart
21. Don't Close Your Eyes
22. When Heaven Comes Down
23. Into the Fire
24. Bullets to Spare
25. Alone Again
26. Turn on the Action
27. Unchain the Night
28. The Hunter
29. In My Dreams
30. Slippin' Away
31. Lightnin' Strikes Again
32. It's Not Love
33. Jaded Heart
34. Don't Lie to Me
35. Will the Sun Rise
36. Til the Livin' End
Dokken: Composer, Lyricist, Producer, Original Recording Producer
Don Dokken: Guitar, Composer, Vocals, Producer, Original Recording Producer, Group Member
John Tirabasso: Project Assistant
John Norum: Guitar, Vocals
George Lynch: Guitar, Composer, Lyricist, Group Member
Angelo Arcuri: Producer, Original Recording Producer
Roy Thomas Baker: Associate Producer
Peter Baltes: Bass, Vocals
Hugh Brown: Art Direction
Juan Croucier: Bass, Group Member
Christopher Currell: Programming
Wyn Davis: Producer, Original Recording Producer
Barry Diament: Mastering
Dan Hersch: Remastering
Bill Inglot: Producer, Remastering
Neil Kernon: Producer, Engineer, Mixing, Original Recording Producer
Michael Lardie: Assistant Engineer
Bob Ludwig: Mastering
George Marino: Mastering
Gary McGachan: Engineer
David McIntosh: Licensing
David McLees: Compilation Producer
Ted Myers: Project Supervisor
Jeff Pilson: Bass, Composer, Keyboards, Vocals, Vocals (Background), Group Member
Michael Wagener: Producer, Engineer, Mixing, Original Recording Producer
Tom Werman: Producer, Original Recording Producer
Billy White: Guitar, Composer
Bob Defrin: Art Direction
Mikkey Dee: Percussion, Drums
Neil Zlozower: Photography
Mark Weiss: Art Direction, Photography
Patrick Milligan: Project Supervisor
Elizabeth Pavone: Editorial Coordinator
Jodi Rovin: Design
Steven Chean: Editorial Supervision
Steve Woolard: Research Assistant
Emily Cagan: Compilation Producer
Lori Carfora: Design
Mark Wilczak: Assistant Engineer, Mixing Assistant
Dave "The Knave" Williams: Logo
Daniel Goldmark: Editorial Research
Rick Sales: Project Assistant
Tom de Savia: Project Assistant
Virginia Haverick: Project Assistant
Wendi Cartwright: Licensing
Wild Mick Brown: Composer, Drums, Vocals, Vocals (Background), Group Member
Katherine Turman: Liner Notes
Pilson: Composer, Lyricist
Markus Spiro: Composer
Cliff Bonell: Assistant Engineer
Harry "D.O.G." Barone: Art Direction, Concept, Execution
Guy Perkins: Sleeve Photo, Back Cover Photo
Rob Jones, Jr.: Sleeve Photo, Back Cover Photo


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Product Recall: Kraft and Polly-O String Cheese and String Cheese Twists. Click here
They're delicious served on their own with a little sugar and cream, baked into pies and cobblers, or turned into jams, jellies and sauces. Pick up a pint or two at a farmer's market and add them to your favorite summer meals.


text: Worried about Grace, Jackie leaves rehab early against the medical advice of her counselor and returns to a very different All Saints. On top of the Quantam Bay takeover, this is the first time she's had to work sober. Almost instantly her nerves are rattled, and even Coop hurts her feelings.


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Enjoy free shipping both ways this holiday season. If for some reason you are not completely satisfied with your purchase, choose our FREE pre-paid shipping label and we'll cover your return! This offer is only good on eligible orders placed between November 13, 2013 and December 24, 2013. We've extended our normal return period to January 15, 2014 or 30 days after your order is received - whichever comes later. Learn more about our return policy.
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The Danielson Fishing Lure Weight Downrigger adds weight to your fishing lure to help getting your lure to the right depth. This Fishing Accessories by Danielson is designed with a keel to ensure accurate tracking and to prevent cable twisting. The Danielson Fishing Lure Weight Downrigger w/ Reflective Prism Tape features reflective prism tape that is attached to both sides of the keel for sparkle and flash. The Danielson Fishing Lure Weight Downrigger w/ Keel has vinyl coating that protects both boat and downrigger weight.


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Song Lyrics by HAVANA CASINO ORCHESTRA
Browse our endless online lyrics database to find lyrics for virtually any song from any style of music: hip hop lyrics, pop lyrics, rap lyrics and many more. Our HAVANA CASINO ORCHESTRA Section contains all the songs you could possibly want. Browse our entire collection of HAVANA CASINO ORCHESTRA SONG LYRICS for free!
We're sorry but the artist has decided not to disclose the lyrics for this song. |


text:
- December 6, 2012
- 7:03 a.m.
- Suggest removal
- Reply to this post
moretrax writes:
Glad to see Purdue open up the wallet to get a quality coach from outside the program rather than promote a "coach in waiting" Looks like this is a multi-year deal with the entire package of $12m.
If Coach Hazell and his staff can recruit well, Purdue will be a solid contender.
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The marlin is a large game fish.
It has an elongated body, up to 2.5 m long, a spearlike snout, and a long rigid dorsal fin, which extends forwards to form a crest.
Marlins are fast swimmers, occurring in all seas and hunting small and large fish.
For more information about the topic Marlin, read the full article at Wikipedia.org, or see the following related articles:
Note: This page refers to an article that is licensed under the GNU Free Documentation License. It uses material from the article Marlin at Wikipedia.org. See the Wikipedia copyright page for more details.
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Lessons From Boston
RWJF Clinical Scholar Jeremiah Schuur, MD, an emergency physician at Brigham and Women's Hospital, helped treat many of the Boston Marathon bombing victims. Here's what he learned.
You are now viewing 1 - 10 of 22 results
October 28, 2013 | Story
Barcode scanning has made tracking mail packages and consumer products easy, so why not use it to keep tabs on patients during a disaster?
April 26, 2013 | Story
An RWJF Clinical Scholar shares lessons from the Brigham and Women's ER on the day of the Boston Marathon bombing.
October 10, 2011 | Story
RWJF Clinical Scholar uses personal connection to disaster-stricken country to help improve quality of care, inform research.
September 23, 2009 | Story
October report will go to President Obama.
August 11, 2009 | Story
Using the toolkit, hospitals can improve the overall quality of pediatric emergency care across the country by meeting national guidelines for care issued by ACEP and the AAP.
December 15, 2005 | Commentary, Story
In this commentary, the Honorable Thomas H. Kean, M.A., chairman of the board of trustees of the Robert Wood Johnson Foundation, and Risa Lavizzo-Mourey, M.D., M.B.A., Foundation president and CEO, propose a three-pronged strategy to prepare for public health emergencies. This commentary appeared on the opinion page of The Philadelphia Inquirer.
February 26, 2009 | Story
Graniteville, S.C., event has national implications.
This story is a summary of a forum hosted by RWJF to raise awareness of the lingering mental health effects from Hurricane Sandy.
August 7, 2013 | Story
Kimberly Dilosa-Byas was named a RWJF special Gulf Coast Community Health Leader in 2006, a recognition of her work to provide programs that keep New Orleans teenagers occupied, safe, and off of the streets.
July 3, 2013 | Story
Unused medical supplies go to global aid projects instead of landfills, thanks to a student-run group founded by an RWJF scholar.


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Traffic Estimations
Traffic Rank
23,630,513th most visited website in the World
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Freehumanity.net is ranked 23,630,513 in the world (among the 30 million domains).
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Alexa Rank: | 23,630,513 visit alexa | |||||
Alexa BackLinks: | 3 | |||||
Traffic Rank
Traffic rank for baiturrahim.com, a low rank means that this website gets lots of visitors
Estimated percentage of global internet users who visit baiturrahim.com
Estimated percentage of global pageviews on baiturrahim.com
Estimated daily unique pageviews per user for baiturrahim.com
Bounce %
Estimated percentage of visits to baiturrahim.com that consist of a single pageview
Time on Site
Estimated daily time on site (mm:ss) for baiturrahim.com
Search %
Estimated percentage of visits to baiturrahim.com that came from a search engine
Web safety analysis
baiturrahim.com is website. This information from Google, AVG Threat Labs, McAfee SiteAdvisor, Wot
Copy & paste code at your website:
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We found 559 429 websites. With this list of domains you can view websites hosted on a given IP address.
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baiturrahman-pkt.org | |||
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Backlinks History Analysis
At the last check on 2013-11-28, we found 1 backlinks.
The highest value is 1, the lowest value is 1, the average is 1.
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Last found backlinks for baiturrahim.com (1 total - download all links in cvs format):
Domain | Google PageRank | Popularity |
fivequeen.net |


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, ,
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Composition: Spandex/Elastane 3%, Composition: Viscose 97% WASHING INSTRUCTIONS : Machine WashBrand Style ID : D226P318IDV
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- Mudstep 6000 Subscribers Mix Artwork
Mudstep 6000 Subscribers Mix
mudstep on December 08, 2012 19:36 - Mudstep 5000 Subscribers Mix Artwork
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mudstep on September 14, 2012 02:12 - Underground and Underrated Vol. 1 Artwork
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mudstep on January 10, 2012 02:07
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Wednesday, June 20, 2012
Why did I get left behind?
Arthur is a wise, docile older boy with a heart of gold.
He asks for so little, but has enormous unconditional devotion to bless you with if you adopt and make a lifelong commitment to him.
Arthur is a handsome Chihuahua, neutered, 10 years of age, great with other dogs, and ready for adoption at Nevada SPCA.
His previous owner moved away without him.
Special thanks to Pet'ographique for this illuminating portrait to help Arthur find a loving home.


text:
- June 16, 2011
- 1:41 a.m.
- Suggest removal
- Reply to this post
naplesnewby writes:
Extend the runway, planes will be quieter taking off. And HOPEFULLY it would eventually lead to commercial services...? It was such a blow to this locale to lose those services.
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"Why has the scandal created outrage in Britain? Because it truly is outrageous. They weren't supposed to be fixing that rate — no matter what the reason. If I give you my money, I need to be able to trust you with it. If you can only be trusted via regulation, then you might as well be a utility. And if banks can't be trusted to manage their trading desks, then we need to rethink our whole model of banking."
— Karen Petrou, the managing partner of Federal Financial Analytics, regarding Barclays' LIBOR scandal


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Napoleon Township will make informed decisions based upon the entire Township and build trust and integrity by working together to achieve common goals for our community. NOTICESThe Napoleon Township Planning Commission recently completed a draft of the 2012 edition of the Napoleon Township Master Plan. The draft Napoleon Township Master Plan is available for a public review period between August 20, 2012 and October 22, 2012.- Click here to review the Draft Master Plan in PDF format Adopted amendment to the water ordinance to regulate the use of ground water in certain areas of the township - Water Well Restriction Ordinance No 95.03 Click Here to report Street Light problems Click here to view the Napoleon Township Audit information Click here for Michigan Winter Hazards Awareness information Click Here to visit the Census Bureau's website to view the history of apportionment and our country's changing population through the past century. Township Board Meetings for 2013January 8, 2013 at 6:00 P.M.February 12, 2013 at 6:00 P.M. March 12, 2013 at 6:00 P.M. April 9, 2013 at 6:00 P.M. May 14, 2013 at 6:00 P.M. June 11, 2013 at 6:00 P.M. July 9, 2013 at 6:00 P.M. August 13, 2013 at 6:00 P.M. September 10, 2013 at 6:00 P.M. October 8, 2013 at 6:00 P.M. November 12, 2013 at 6:00 P.M. December 10, 2013 at 6:00 P.M. Jackson District Library Napoleon BranchHOURS OF OPERATION Monday 1:00 P.M. to 6:00 P.M. Tuesday 1:00 P.M. to 6:00 P.M. Wednesday 10:00 A.M. to 2:00 P.M. Thursday 10:00 A.M. To 7:00 P.M. Friday, Saturday and Sunday Closed In addition to books, our library has CD'S, VHS tapes, DVD disks, and computers, with internet access.
Floodplain InformationIf you have received notice that you are in a floodplain and believe that your structure is not in the 100-year floodplain click here |
Hours of Operation:
Monday through Thursday
7:00 A.M. to 5:00 P.M. Closed: |


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As a pediatrician and a mom raising five kids, I've had plenty of experience giving medications to children. Most children take their medicines. Some children may need cajoling or snuggling, or a dose of sternness or rewards (read: bribes). But the stuff usually gets where it needs to be. But with some children, it's a different story. Medicines are met with firmly clenched teeth, or spill — or spray — out of the mouth because the child won't swallow. And that's assuming you can catch the child and get him to hold still. My daughter Elsa was the worst: after catching her and struggling to get the medication into her, she'd look at me angrily and vomit every last bit as if summoning it from her stomach. So what do you do if you have one of those children? Here are my tried and true suggestions. Before you leave the doctor's office with a prescription, let your doctor know you have a problem child when it comes to taking medicine. There are actually several things your doctor can do to help, such as:
When you get to the pharmacy, let the pharmacist know about your problem too, because he or she might be able to:
Here are some tips for actually giving the medication.
If you have a baby or toddler who is a real struggler, here is a hold a nurse taught me. It's not pleasant, but it gets the job done:
If nothing works, call your doctor. Never, ever stop a medication without letting your doctor know. And be patient with your child; with time, it will get better. (Elsa stopped the vomiting well before kindergarten.) Of course, by then you will be fighting about something else...but that, after all, is parenthood. Claire McCarthy, M.D. is an assistant professor in pediatrics at Harvard Medical School, an attending physician at Children's Hospital of Boston, and medical director of the Martha Eliot Health Center, a neighborhood health service of Children's Hospital. She is a senior medical editor for Harvard Health Publications.


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Become a member today. It's free.
We will not release or resell your information to third-parties without your permission.
Good .make you bed sleep in it....no one listen to you anyway......at my home country people like you have fingers cut and tongue cut out.........
Soon to be much violence and oil go very high happy to live in canada


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speed test related software
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Speed up Windows XP or Vista for free with New Technology


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PCC Site
PCC People
skip to main content | news | calendar | directories | employment | contact us
ATTENTION SPRING 2012 LIBRARY 1 STUDENTS: All students must attend the in-class orientation on Monday, April 23, 2012 from 6:00 PM-7:30 PM. Those not attending will be dropped from the class. Any questions? Contact me at email@example.com
I look forward to meeting everyone on April 23!
Revised 09/17/2013 by firstname.lastname@example.com


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My recent comments
- Ahhh, this is super cute I love it! :D The colors are great, too. Sad...
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- I LOVE the Turtles art on the side. :D


text:
The Federal Government released the final report on 22 December 2009. An excerpt follows.
By embracing Government 2.0 we can:
Government 2.0 will be central to delivering on critical national objectives including delivering on our National Innovation Agenda - including the aspiration for a more innovative public sector. It will be central to addressing the desire of the Advisory Group on the Reform of Australian Government Administration to establish in Australia the world's best public service which puts citizens at the centre of everything it does. It will be an important component of the Department of Human Services service delivery reform agenda. It can improve social inclusion.
And it will enable us to make the most of our huge broadband investment making Australia a more connected democracy.
The report is available from the Australian Government Information Management Office, Department of Finance and Deregulation.
Last updated: 22 December 2009
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Christopher Corona
Nov 6, 2013
Shantel Demand
Oct 30, 2013
Home » News » Crime
Murdered Manchester mother had stab wounds, slashed throat
Michelle Hogarty, 46, of 316 Mammoth Road, died from "multiple stab and incised wounds of her neck," according to an autopsy performed Thursday by Chief Medical Examiner Dr. Thomas Andrew. The manner of her death was a homicide, he ruled.
John Hogarty, 53, Hogarty's husband of 10 years, is being held without bail, charged with first-degree murder in her death.
Mrs. Hogarty last worked about three years ago as a part-time cashier at a local grocery store, but was a stay-at-home mother of a 6-year-old son at the time of her death. Described by friends as a sweet, caring mother, Hogarty had recently battled throat cancer and fibromyalgia, which causes body-wide pain.
The murder investigation is continuing and anyone with information about Hogarty's death is asked to call Manchester police detectives at (603) 668-8711 or Manchester Crimeline at (603) 624-4040.
What's next:A probable cause hearing is set for May 14 in 9th Circuit Court, Manchester District Division.
- Affidavit reveals details in church school thefts - 0
- Judge rules to keep officers on Laurie list - 0
- Conn. man charged in hit and run - 3
- Manchester gas station burglarized - 0
- Dingman granted conditional parole - 6
- Goffstown man held in Triangle Credit Union robbery, burglaries - 1
- 2 Bay State men arrested for Peterborough credit union robbery - 1
- Hudson man facing DWI charge after crash - 0
- Police recover stolen SUV investigating burglary - 0
Dingman: 'I try to be a better person'
READER COMMENTS: 1- Fed uncertainty sends Dow, S&P 500 down - 0
- Exploring the dark side of social media - 0
- Nashua asks DOT to build $3.6M roundabout on East Hollis Street - 0
- St. Mary's Bank's mural finds a new home at genealogy society - 0
- Divisions still under discussion - 1
- Fred Upton, a lawyer who made NH better - 0
- Allen Lessels' UNH Notebook: Wildcats' fortunes at Maine may rest with the big guys - 0
- Monarchs continue their battle of the Atlantic - 0
- Sen. Rausch wants state's gas tax tied to consumer price index - 0
FBI remain 'concerned' for Hernandez, plan to share new information
READER COMMENTS: 0- Should applicants for jobless benefits have to pass a drug test?
- Yes
- 78%
- No
- 22%
- Total Votes: 1424


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Mohammad Athar Hussain started the forum topic Greenhouse and window farming together in the group For Beginners: 1 year, 4 months ago · View
I am new here. I want to ask if it is possible to utilize this technology inside a green house for mass production? What are the precautions which one should keep in mind to start a mass scale production in a green house. Off course after mastering techniques in small scale. -
Mohammad Athar Hussain joined the group For Beginners 1 year, 4 months ago · View
Mohammad Athar Hussain became a registered member 1 year, 4 months ago · View


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View all available promotions
This was a good stay. Nice and clean. Staff was professional and freindly. See full review
This was a good stay. Nice and clean. Staff was professional and freindly.
First day coincided with the Tall Ships Regatta and the town and hotel were swamped. Room... See full review
First day coincided with the Tall Ships Regatta and the town and hotel were swamped. Room...
Customers who viewed Radisson Blu Marina Palace Hotel, Turku also booked these hotels.
Rates quoted in currencies other than the hotel's base currency are subject to the rate of the international exchange. Rate may change throughout stay. Rate may reflect average nightly rate. Extra charges may apply. Incidental charges, such as room service, are not included in the rate.
The amenities and/or facilities may not be located at the hotel, but within a reasonable distance, and additional charges may apply for use. All information has been provided by this hotel and not by Orbitz
Ratings and reviews for Radisson Blu Marina Palace Hotel, Turku
Overall score
100% would recommend to a friend.
Reviewer score
Would recommend
Nice Clean Place
Three day stay
First day coincided with the Tall Ships Regatta and the town and hotel were swamped. Room overlooked the river and was very nice. Things were quieter the next two days, but even when full our room was quiet and the beds were great. Only problem was the elevator that we were stuck in for 30 minutes and the sofa in our room which was not comfortable for sitting with ones feet on the floor. The location was great for strolling along the river and visiting the major attractions - castle and maritime museum on one side and cathedral and handicraft museum on the other.
oldest pizzaria in Turku has excellent food, not only pizza - The name, as best I remember is Dennis
Great hotel
I needed assistance getting to a ferry to an island in the archipelago. The front desk went to the trouble of letting me know which bus to take, and how to make my ferry connections. Great and friendly people, nice place to stay.
The restaurant has a very nice breakfast included in the price of your stay... and dinner there was also very good.
Very comfortable, friendly service
Right on the river that organizes the city. Fifteen minute walk or ten euro taxi ride from railway station. Spacious room for Europe, friendly front desk staff, excellent breakfast buffet -- paying the rate that includes breakfast is definitely a good deal, at least for a couple.
Superb Turku city hotel
This hotel in Turku Finland is located on the river and is a delightful place to stay for pleasure or for business. The staff are friendly and helpful and the breakfast buffet is legendary. The decor is modern with wooden floors in the rooms and very comfortable furniture. Some rooms even have their own private Finnish wooden sauna, and there is also a large sauna and steam room open to all guests on a main floor.
Hyvä sijainti
Hotelli sijaitsee hyvällä paikalla, keskeinen sijainti, hyvä varustelu ja palvelutaso, erinomainen hinta-laatu suhde. Loistava aamupala ja muut tarjoilut. Autolla voi tulla, parkkipaikka yhtä hyvin järjestetty.
Erinomainen sijainti. Ihanan pehmeät peitot ja tyynyt, oikein makosat unet :) Erinomainen aamupala!!!
Tarjoilijat aamiaisella
Harvoin olen nähnyt niin iloisia ilmeitä ja positiivista tunnelmaa aamiaisella hotellissa, siis tarjoiluhenkilökunnan puolelta! Hotelli oli taynnä ja henkilökunta hymyili ja tervehti iloisesti kaikkia. Kiitos! Amerikan vieraammekin oli huomannut saman! Jatkakaa samaan malliin!


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Currently Unavailable Artist: Leaders of the New School
Genre: Hip Hop
Release Date: 1991
Label: Elektra
Catalog Number: 9 60976-1
Recording: Studio
Sound: Stereo
Format: LP
Artist Releases
Leaders of the New SchoolFuture Without A Past (CD)
Leaders of the New SchoolA Future Without A Past (LP)
Leaders of the New SchoolCase Of The P.T.A. / Teachers Don't Teach Us Nonsense (12" E.P.)
Leaders of the New School
Label Releases
More Than Just A Dream (LP)
Fitz And The TantrumsMore Than Just a Dream (CD)
Fitz And The Tantrums - Out Of My League [RECORD STORE DAY] (12")
Fitz And The TantrumsMarquee Moon (LP)
Television - Live At The Bowl '68 (LP)
The DoorsCee Lo's Magic Moment (CD)
Cee-LoReinventing The Steel (LP)
Pantera - View More
A Future Without A Past (LP)
Leaders of the New School
Currently Unavailable
SHIPS FREE in U.S.


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Are Women Safe In India?
By editor
The brutal rape and death of a young student in New Delhi is raising concerns about violence against women in India. To find out more about the challenges women face in the world's largest democracy, guest host Celeste Headlee speaks to a women's rights advocate and an Indian author.