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Scott's Pet Pics
Contribute your pet photos to this gallery by emailing them from your computer or smartphone to firstname.lastname@example.com
Keeping the house safe odie is part otter hound and the sweetest most mischevious girl ever: she likes to go into my purse and steel chocolates and take dishes out of the dish pan to further clean
Our rescued cocker Sadie. We got her from Wisconsin Cocker Rescue 3 years ago. She is 9 years old. Pete and Sherry of Hartford, Wi.
Message Subject: Leslie's Family Dog This is all the presents this year. Rocky the family dog waiting for Santa! Submitted with permission by Jan Phelps ~ Racine
This is Keena, 3 yr old German Sheppard who loves to play in the snow, it is her favorite time of the year!! Mandi from Milwaukee
I am Emily from Waukesha. This is picture of my 2 year old girl cat Jaxxy keeping warm on her blanket. Emily from Waukesha
Our dog Blue loves Christmas, especially lights. His boy Allen loves to decorate with lights. When they get together crazy things can happen! Don't worry, they are battery operated lights and Mom quickly brought the festivities down a notch. I did take a quick picture though. Carrie
Cant wait for santa to bring her gifts kellie and jason
Max doesn't like giving elves a ride
Hi Scott, Happy Holidays! This is a photo of Freckles and Daisy (dalmatian)They are both rescue dogs. They are waiting for Santa! Les and Renee' Piotrowski
Cinnabun photo bombs moonshine Jenna
She loves playing with her boys aaron and ethan kellie and jason
8 Month old Leni meeting Santa for the first time! Beth Heckel
This is packer fan Rusty celebrating the packers win!!! The Frey family
Eight year old Finnegan enjoying the Christmas tree! Bridget Donovan,
Frank & Eunice Littlefield with Chibe
Hailee with Santa
We'd like to share this picture of Lou rocking his John and Terri Lukasavitz
Marcey Frankiewicz
Marcey Frankiewicz
We'd like to share this picture of sisters Chloe and Charlee looking festive for the holidays! Bob and Denise Roszak, South Milwaukee, WI
Christmas picture of our five dogs: Pink, Cait, Madigan, Tully, and Dublin Todd Whitney
Our yellow lab Ashley is waiting to help Santa
Spike and Smokey have been good this year. Danielle and Craig Walter
This is Beau sitting by the Christmas Tree watching the snow on Sunday, December 8t from his comfy couch in Racine. Tobi Weingart
Satsh is an eight year old Polish Lowland Sheepdog. He lives with his human parents Tom and Diane Pirc in Hartford Wi. He has a little sister Paczki age 5, also a Polish Lowland Sheepdog. She is camera shy. Besides all of his many accomplishments in the show ring Stash is in his third year at the Hartford Library helping children with their reading skills. He is there every Saturday from 9:30am until 1:30pm. There is no charge. Everyone is welcome. He is licensed, registered and insured by Therapy Dogs International. Yes
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My name is Sandi. I'm 13 years old and super sweet. I can't wait to see what Santa Paws puts in my stocking this year. Joyce in Elkhorn
Zak and Moppy from Twin lakes. MERRY CHRISTMAS, On-air
This is my dog buddy. We're so close, we even share clothes. And by share clothes, I mean I dress him up and he gives me these looks! Brianna from Milwaukee
Here are a few pics of my pets... 1st pic is Little Puff and she is ready to play! 2nd pic is Little Boy who just wants to lay by the fire.. 3rd pic is Chopper who was upset he wasn't getting his pic taken.. So he has on the cat's hat...
Here are a few pics of my pets... 1st pic is Little Puff and she is ready to play! 2nd pic is Little Boy who just wants to lay by the fire.. 3rd pic is Chopper who was upset he wasn't getting his pic taken.. So he has on the cat's hat...
Here are a few pics of my pets... 1st pic is Little Puff and she is ready to play! 2nd pic is Little Boy who just wants to lay by the fire.. 3rd pic is Chopper who was upset he wasn't getting his pic taken.. So he has on the cat's hat...
This is Bella. Thinking what I won't do for a cookie. Tim & Pam Hewett West Bend
My two year old and our new family pet Charlie I found taking a nap together on the couch. How could I resist not taking a photo and sending it in to tmj4? Abbi Plants of Lake Geneva
Hi Scott! We are 15 month old guinea pigs who want to wish you and all the viewers Happy Holidays! We watch you every morning while our mom gets ready for work! JeanMarie Jones - Greenfield, WI
This is my very tolerant orange tabby. Barbara Bartlein
We adopted Smokey from the Wisconsin Humane Society this year. He is 16 weeks old. I hope you consider putting him in your Scott's Pet Pics. Thanks! Danielle M. Walter Danielle and Craig Walter
Little ZuZu says
Attached is a print of our dog Ben, who is a 3 year old Rat Terrier sitting on Santa's lap at the Waukesha Humane Society excited to let Santa know his list of toys and treats to get this year. Ben always has a smile with his tongue hanging out. Sharon Harding, Sussex
This is a picture of my Dog Brody in his Dawn Cook
This is a picture of my Dog Brody in his Dawn Cook
We bought the dogs new dog beds this weekend, but they are a little confused with who gets which one! Ha ha Kathy Kalis
This is our dog
This is a picture of the last Christmas we had with out pet, Sarah. She lived a happy 14 years with us. Scott And Joy
This is Yana (3yr old female Siberian Husky) and Leo (10 yr old male Egyptian Mau mix) taking a nap in the sun on Yana's bed. Well, Yana is almost on her bed! Dee Cramer - Raymond WI
This is a pic of my new puppy Lulu having fun with reindeer ears. As you can see she wasn't thrilled but was still cute as a button! Kerry Herro
Hi tmj4! I thought I would share a picture of my two dogs Bubba and Trigger ready for the holidays! Enjoy :)
This is Molly. She is 5 years old. We got her when she was 2 and enjoy her little personality every day. She loves to be in your lap and run and play.
Bonnie Dehne
Here are 2 pictures of our cat Propnut helping with the lights for our Christmas tree. He is a 2 1/2 year old seal-point siamese. Pete and Marie Spear Salem, WI
Here are 2 pictures of our cat Propnut helping with the lights for our Christmas tree. He is a 2 1/2 year old seal-point siamese. Marie and Pete in Salem
CC is getting ready for santa doggy! DeDe
Here is a picture of Bear a few christmas years back. This is yearly tradition with him climbing the tree! One year the tree came down with him. Theresa
Here is a picture of Bear a few christmas years back. This is yearly tradition with him climbing the tree! One year the tree came down with him. Theresa
This is Jazz our two year old cat. During the holidays he enjoys wearing his Santa hat throughout the house. He doesn't seem to mind dressing up like Santa, although it terrifies his brother Dusty. The Fehr family
Hi! Happy Thanksgiving! I thought I'd share my Corn Dog with you. This is Willow - aka - Willie Wonka Weimaraner (as she can be found on Facebook), and we make a calendar each year of my favorite photos of her, as a fundraiser for the Northwoods Humane Society in Hayward, WI, where one of our other dogs is from. I hope you enjoy my Corn Dog as much as I enjoy sharing her photos. (The corn cob is NOT photoshopped in! Everyone asks me that. She holds anything I ask her to, for the most part, and also balances a wide variety of things on her head.) I know...I'm one of those crazy dog people, and I'm okay with that! :) Thanks. Katy Felton-MooreHubertus, WI Katy Felton-Moore
Chewee at the bar watching the Packers.
Harley, our two month old pomapoo! David Kania
This is Molly - our 9 year old, EXTREMELY shy Sheltie. She is not a fan of the outdoors - but she does like to know what kind of weather to expect when she needs to "go" outside! Tammy from Wauwatosa
This is Molly - our 9 year old, EXTREMELY shy Sheltie. She is not a fan of the outdoors - but she does like to know what kind of weather to expect when she needs to "go" outside! Tammy from Wauwatosa
This is my new roommate Boyd, he is a 11 year old Maine mixed cat. I photo shopped the santa hat on him for my Christmas cards this year.
... not even a ... malamutt! Clint Eastwood is our resuced malamutt - malamute, shepherd, greyhound, beagle mix who just turned two. Wakey wakey eggs and bac-key! Mara
Our 9 week old Boxer.
Angus is our 2 year old Puggle rescue. He along with us watch the TV4 am program & Scott Steele told us it was going to be cold & windy for the big Christmas Parade downtown that he was to be in. So what does a puggle wear mom knows an Ugly Dog Christmas Sweater!! Thanks Scott for all the cute animal pics you have on the program. We missed Kaitlyn & Cash this year. Kathy/West Allis
Buddy and Rikki tikki Tembo no sa rembo Chari Bari Ruchi pip peri Pembo Ricky for short aka Pete and repeat
This is our best friend Roscoe! He's 6ish (based on the shelter's best guess). He loves field trips in the car, where this photo was taken. He also loves sleeping under the covers with his head on the pillow just like a human. He's very gentle with kids of all ages, and we would love it if he could be featured in Pet Pics! Kelly West, Mequon
This is George! He is just a happy happy guy!!! And he loves the crisp frost of the early morning! Lorrie from Theresa
Scarlette and Itsy Bitsy. Laila Wiechmann
Stuart is my 6 year old cat. His ears are always cold so I put this hat and scarf on him. He loved it and just sat there with them on. He's a inside cat but dresses for the cold outside. Laura Monfre
Stuart is my 6 year old adopted cat. His ears were cold so I put this hat and scarf on him. He just sat there warm and cozy. Laura Monfre
I was hoping you would put this picture of Stuart Monfre on when showing pets on the news. Laura Monfre
Stuart Monfre lets me dress him up and will just sit there. He's a 6 year old adopted cat that stays indoors but still likes to say warm and cozy. Laura Monfre
Zoey is a big JJ Watt fan and shows it Rick - North Prairie
This is Maya. She's in her prairie dog pose while begging for a T-R-E-A-T Shayne
Zoey is a big JJ Watt fan and shows it Rick - North Prairie
Kim & Mark
Kim & Mark
Brodie loves jumping in the leaf piles! Taylor
My son and his kitten Charlie laying together. Abbi from Lake Geneva
Hi there. Please find a photo attached of our dog. This is Eli - sitting on top of his buddy, AJ Taylor. Chris and Kristine Martynski
My husband snapped this picture of Juno and I sleeping on the couch on a Sunday morning. Juno is a high-energy rat terrier mix, so it is rare for her to be this calm. She looks so human in this picture. Ruth
my daughter Rachael and kitten Charlie, sooo cute!! I took this in the dark not knowing how cute it would turn out Heather B.
This is Sophie! I just told her you said it was going to snow soon!!! She couldn't believe her ears!!!
This is my cat Foxegirl. We were actually watching the 10:00 news in bed. And yes of course it was WTMJ4. The best news ever and that is the truth. Isn't Foxegirl a cutie pie? Debora Coleman
Foxegirl on the bed post doing a balancing act. Look at her pretty eyes. She is just a joy to be around . Debora Coleman
Smokey Bear is checking out the dyson fan. He's probably wondering if he could walk through it. He is sweet and very spoiled. Debora Coleman
He will sit there all day and watch the animals, lucky he does not have a gun.
Smokey getting ready for the day
Rufus, our loveable Labradoodle prepared for Sunday's windy weather with his aviator goggles and hat. His human sister Olivia may have had something to do with this get up! Olivia & Kim Schmidt
Scrappy has a case of the
This is a pic of my cat Bella.....we adopted her about a year ago from the Lakeland Animal Shelter....this is her favorite spot to hang out in the morning sun....loves it when Scott forecasts Sue Polivka Elkhorn Wi
Wanting to come outside to see me. Love the beauty of this picture of her. Jennifer Rausch


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BETHPAGE OLD BETHPAGE ISLAND TREES PLAINEDGE SEAFORD VOL. 16 NO. 1 The Week of April 9 - April 15, 1981 20 cents per copy People In The News x RENDERING AN OPTIMISTIC JUDGEMENT: Hempstead Town Councilman Peter King [rear, 2nd left], a judge at the Optimist Club of Levittown Oratorical contest, is joined by contestants and officials prior to the event's commencement. Joining Councilman King at the contest are [front, L-R] Scott Lessing, Ronnie DuHamel, Gary Sunshine, Richard Daniels, Deborah Harms and Lisa Zehenter, all contestants and [back, L-R] John White, timekeeper; Leonard Ornstein, chairman; Louis DiMitri, judge; Charles Bellomo, president and Bill Bry-son, judge. The subject matter for the contest was "A Commitment to Share" and the winners Gary Sunshine and Lisa Zehentner, will compete against the winners of the New burgh area contest on April 15th, with the overall winner receiving a $600.00 scholarship from the N.Y. District of Optimist International. Assemblymen Lewis J. Yevoli [left] and Bill Bianchi [right] discuss their legislative proposals aimed at reducing rising utility rates with New York State Attorney General Robert Abrams. L F V! COUNTY SHIELDS HONORED: Hempstead Town Presiding Supervisor Thomas S. Gulotta (left) presents a Citation for outstanding community service to the Shields of Nassau County, a fraternal orgnanization of police officers who either work or live in the County of Nassau. Representing the Shields are 2nd Vice President Hugh Kelleher of North Merrick (center); Vice President Richard J. Petito of Massapequa (2nd right) and President Joseph J. Klun of Seaford (right). Also attending the presentation ceremony is Town Clerk Daniel Fisher (2nd, left). Thirty-Nine High School Students Inducted Into Natl Honor Society During a Candlelight Ceremony at Antun's Restaurant in Hicksville on Wed., Apr. 1, 1981, thirty-nine Bethpage H. S. students were inducted into the National Honor Society. The induction banquet was attended by one hundred and sixty friends, parents, and Honor Society Members. The Mistress of Ceremonies was Virginia Walsh, president of the Bethpage H. S. Chapter of the Honor Society. Other members of the Society who participated in this impressive ceremony were Mark Rauch, Susan Graziose, Nathaniel Lim, Doreen Keenan, Peggy Fahr, and Martha Grizzaffi. New members who were inducted on April 1, 1981 were: Diane Bascelli, Linda Chambers', Betty Ann Chodkowski, Loriann Conti, Robert Cooper, Fran DiLeonardo, Lisa DuBritz, Stephen Eliseo, Diane Furrey, William Hayes, Thomas Jacobs, Jeanne Keenan, Kevin Laraia, Donna Levin, Lyndon Lim, Donna Loser, Vicki Mayo, Susan McDonnell, Mary Mertz, Matthew Mitchell, Al Nigro, Colleen O'Connor, Nicholas Pasyanos, Gregg Patalano, Meredith Rigby, Randi Samet, Ann Schiavetta, Jonathan Shaw, Lisa Shushan, Christal Siewertsen, Ira Silfin, Larry Stein, Ronny The, Richard Veras, Clare Walsh, John Wolfe, Joyce Woodruff, Lisa Zetkov, Alisa Ann Rietschein. Fifth Annual Bethpage Dad's Club Invitational Lacrosse Tournament The 5th Annual Bethpage Dad's Club Invitational Lacrosse Tournament will be held at the Bethpage High School Field on April 11th & 12th starting at 1:00 P.M. Bethpage will be hosting teams from Massapequa and Baldwin plus one upstrate team, Fox Lane. The Tournament is held for the benefit of the High School Scholarship Fund. In prior years, teams from the Catholic School Conference and other upstate communities have participated in the Tournament. In 1979 Berner High School, Massapequa was defeated by Bethpage (8-6). Bethpage had broken this game open in the third quarter when John Poggie and Dan Boltja scored back-to-back goals within a 42 second span. In 1980 Berner took the Tournament championship when Bill Dempsey, their all-conference attackman, drove home an unassisted goal with a minute left in the game to give Berner a 7-6 victory over the Bethpage Golden Eagles. This year Berner will be playing without either Dempsey or their ail- American mid-fielder Scott Gerham. The Golden Eagles will be missing John Poggio, AU-American attackman and Dave Keenan, all-American goalie. Both are now playing for North Carolina State University. Also missing from the Bethpage line up will be all-conference players Kevin Walakovits (Washington & Lee) and Rich Lipp (Adelphi). This year Baldwin ranks high in the competition with two outstanding players on the roster - Ed Geiger, 1980 all-league midfielder and Dan Tracy, 1980 all-conference defenseman. According to Fran McCall, coach of the Golden Eagles, Dan Boltja, 1980 all-league player will be leading the Bethpage attack along with outstanding players Wayne Rhatigan and Tommy Draghi. Danny Dunn, 1980 all-league defenseman will anchor a strong defensive squad consisting of Dunn, John Sweeney, Tom Bianco and Rich Waters at goal. All in all, says Coach McCall, the teams in the tournament look quite strong and the competition should really be tough. George McElroy, Principal of Bethpage High School, gives praise to the competition and good sportsmanship shown since the inception of this Tournament. It is his contention that it is people in the Dad's Club, Coaches like McCall, the athletic staff of the participating schools, parents, fans and the athletes themselves, who promote the high quality of the game of Lacrosse which is growing fast on a national level especially in the institutions of higher learning. The coaches from these top colleges and universities come to Long Island first when they are seeking top-quality lacrosse players for their teams. One of the nicest parts of the Tournament takes place late Sunday afternoon when all of the teams players and their parents are hosted to a Dinner run by the Dad's Club vice-president, Luise Greenberg and other club members assisted by the High School Leaders Club. Another very important aspect of this Tournament is the financial support given by our local merchants for our very informative Lacrosse Journal. As you can see these Tournaments are the result of the efforts put forth by many different persons and groups. We need your support too. Come on down on Saturday April 11th and Sunday April 12th and join us for Two exciting afternoons of cheering our Bethpage Golden Eagles on to victory. Admission is just $1:00 donation to the Dad's Club for the H.S. Scholarship Fund. Bill To Cut County Property Taxes By 25 Percent A bill that could reduce Nassau County real estate taxes by 25 percent by having the state take over the cost of Medicaid has passed the State Assembly under the sponsorship of Assemblyman Arthur J. Kremer, Chairman of the Assembly Ways and Means Committee. Last year, Nassau County taxpayers paid $47 million, toward Medicaid costs and the 1981 expenses are expected td increase by almost 20 percent. County officials have been complaining for years that a medicaid relief bill would allow them to make sharp cuts in real estate taxes and take a great burden off the back of the taxpayers. Nassau County has the highest real estate tax rate in the United States. Assemblyman Kremer stated, "I challenge the Republican members of the State Senate to pass this bill as soon as possible so that Nassau homeowners can get a sizeable reduction in their property taxes. One of the key features of this bill is a provision that mandates that the savings gotten by the County are returned to the taxpayers in reduced taxes. Too often the Nassau County administration has used its surpluses for tiny tax cuts and never gives the citizens an opportunity to get honest tax relief." Concluded Kremer, "This bill represents the first ray of hope our hard-pressed taxpayers in Nassau have had in the last fifty years."
Object Description
Rating | |
Title | Bethpage-Tribune_1981-04-09 |
Subject | Newspaper |
Description | This is a Newspaper distributed locally within Bethpage, Old Bethpage, Island Trees, Plainedge and Seaford. |
Creator | Florence Cullem |
Publisher | Florence Cullem |
Contributors | Scanned and Prepared by Hudson Microimaging, Port Ewen, New York 12466. |
Date | 2010 |
Type | Periodical |
Format | PDF; TIFF |
Source | Bethpage Public Library |
Language | English |
Coverage | United States |
Rights | The Newspaper is in the public Domain and Digital Rights Held by Bethpage Public Library. |
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JACKSONVILLE, Fla. – The Second Harvest North Florida Kids Cafe Program has added three sites to its 2009-10 Afterschool Snack Program, a subcomponent of the Child Care Food Program provided through the Florida Department of Health.
Fifty-seven Kids Cafe sites now offer low-income children in its neighborhood a safe place to find nourishment, have positive role-models and participate in educational and social development activities. The program is designed to provide nutritious snacks to children at no separate charge.


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If I sell a product for, say, £1000, and a buyer in another country pays me via a bank transfer, should I expect them to pay the bank charges? Is it something that should be explicit on the invoice - e.g., "buyer pays all bank charges"?
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Answers OnStartups is a question and answer site for entrepreneurs looking to start or run a new business. It's 100% free, no registration required.
Potentially both parties may pay fees, each to their respective bank. In other words the person paying is responsible for any fees charged by his bank while the recipient is responsible for any fees charged by the receiving bank. | |||||||||
When you sell something you set the price of that item or service. If someone wants to pay you in a way that incurs fees, they should pay those fees. But you need to specify that to your customer up front. Both the sending and receiving banks will usually charge a fee to process a wire transfer. In addition, they may also be a currency conversion fee (typically 1%). You need to check with your bank to find out what your fees will be, and you can then ask your customer to pay your fees, or not. | |||||||||


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INDIANAPOLIS (AP) — Firing Bob Knight gave Myles Brand the pulpit to critique college athletics.
Eventually, it helped him change the NCAA, too.
Brand, the first university president to lead college sports' largest governing body, died Wednesday at his Indianapolis home after a lengthy battle against pancreatic cancer. He was 67. It is the first time the NCAA's chief executive has died in office.
"Myles brought his academic experience in philosophy and higher education to the NCAA and effectively challenged the athletics community to demonstrate accountability for the educational values we espouse," NCAA vice president David Berst said.
Whether it was Brand's push for diversity in the college coaching ranks, the desire to put academic progress and graduation rates ahead of wins and losses or his tough stance on the hotheaded and once untouchable Knight, Brand never backed away from challenging the status quo.
That combination forced the Indiana University president onto the national stage in May 2000. It was then Brand announced he was imposing a zero-tolerance policy on Knight following a university investigation into allegations the coach had choked a former player during practice years earlier.
When freshman Kent Harvey accused Knight of grabbing him four months later, Brand responded the way he had promised but that most never imagined he would — firing the revered coach with three national championships.
The decision set off protests in front of Assembly Hall, the Hoosiers home court, and in front of Brand's home where some students hanged him in effigy. Fans debated whether Brand should be fired, and basketball players threatened to quit before the season started.
"That was a very difficult time for Myles, and I know he worked extremely hard to resolve those matters in a very, very different way," longtime Indiana administrator Terry Clapacs said in June. "The way it ended up was not the way he wanted it to end."
Knight later moved to Texas Tech where he became the career victories leader in Division I men's basketball before stepping aside in favor of his son, Pat Knight, in February 2008. Texas Tech spokesman Randy Farley said Bob Knight left Lubbock on Tuesday and wouldn't be back until next month.
But Brand's decision also opened the eyes of a new constituency.
During a January 2001 speech at the National Press Club in Washington, Brand talked about the predicament college presidents faced with "celebrity" coaches and suggested the emphasis on winning championships endangered the real mission of universities — education. He continued speaking to groups about the problems with college sports and in October 2002, the NCAA hired Brand as Cedric Dempsey's replacement.
Brand wasted no time in making changes.
He immediately called for tougher eligibility standards for incoming freshman and current students and led the move for two new academic measurements, the Academic Progress Report and the Graduation Success Rate, real-time statistics of how athletes perform in the classroom that have become common terms around the nation's athletic departments.
"He was able to speak with anyone in any circle, head coaches to faculty athletic reps to any one of the number of committees with the NCAA with the unique position that he had been in their chair, been in their position and heard their voice, heard their concerns," NCAA senior vice president Greg Shaheen said.
Early critics contended Brand didn't know enough about sports to run the NCAA.
But those fears quickly subsided. Many coaches and the coaching associations wound up thanking Brand for listening to their concerns more than his predecessors.
"Myles brought an honest and clear vision to the NCAA that inspired everyone who came in contact with him," said Grant Teaff, executive director of the American Football Coaches Association. "Myles listened, explained his position and acted. It was evident it was his goal to make every aspect of the NCAA better."
In January, Brand announced he had been diagnosed with pancreatic cancer and that his long-term prognosis was not good. He continued working while undergoing treatment, though he did reduce his public appearances. Brand skipped awards presentations in Orlando, Fla., and San Antonio this summer before accepting an award in Indy in late June.
The NCAA has not yet announced who will replace Brand or when a search for his successor might begin.
Two of the leading candidates are believed to be Georgia president Michael Adams and University of Hartford president Walter Harrison, who have served as prominent NCAA committee chairmen in recent years. Also expected to contend is NCAA executive vice president Bernard Franklin.
"I believe being the first university president to be the head of the NCAA set a different tone and a different standard for the NCAA that has been well received by faculty and administrators, both in and out of intercollegiate athletics," Minnesota athletic director Joel Maturi said.
Before taking over at Indiana, Brand spent five years as president at the University of Oregon. He also held administrative posts at Ohio State and led the philosophy departments at the University of Arizona and Illinois-Chicago after starting his career as a professor at the University of Pittsburgh.
Brand earned his bachelor's degree in philosophy at Rensselaer Polytechnic Institute in Troy, N.Y., in 1964 and received a doctorate in philosophy at the University of Rochester in 1967. He is survived by his wife and a son.
Associated Press writers Janie McCauley in San Francisco; Betsy Blaney in Lubbock, Texas; Dave Skretta in New York; Dorie Turner in Atlanta; and Jon Krawczysnki in Minneapolis contributed to this report.
Copyright 2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Barrington Broadcasting is a member of the AP Network.


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Dying is easy, living is hard and pain is a given…
Centuries from now mankind lives on in the Sirius galaxy, an enormously vast and dense system of stars. It's a greedy industrial society run by corporations and the Governmental Industrial Complex. The onslaught of strip-mining has stirred something terrible best left buried and forgotten.
The sci-fi ... [click here for more]
Anything you can imagine, you can play...
HeroQuest is the innovative, dynamic, and flexible rules engine by Robin Laws, suitable for play in any genre or setting. It present a simple and flexible system that allows Game Masters to make decisions the way authors and screenwriters do when creating novels, TV episodes and movies. HeroQuest encourages creative input from your player... [click here for more]
Entre las cuencas del Idigna y el Buranum se encuentra el Imperio de Akkad. Conquistado y gobernado por Sargón el Alquimista desde hace más de 2000 años. Primer y Único Emperador. El más grande desde Gilgamesh. Allí los Awilu viven rodeados del lujo y la comodidad, mientras los Mushkenu y los Wardu, las razas creadas, tra... [click here for more]
Remember when you were young and you were afraid of all those things that went bump in the night?
Ever wonder where they went?
Well, wonder no more because the old monsters are back!
Featuring the classic rules and setting of the original game, this tenth anniversary edition includes alternate mechanics, author commentary, all... [click here for more]
The year is 2644. Humanity has cast off religion and migrated to the stars. With science as the new savior, mankind believed himself to be creating new Edens in the far flung heavens.
But God kept His promise. The day of Rapture came.
click here for more]
Find your DestinyThe savage Titans have escaped their eternal prison to wage war with the Gods once more.Their battles in the Overworld have spilled over to ours.Armed with abilities and weapons granted by their divine parents, the Scions stand as humanity's only defense. This book includes: • Six ready–to–play Scions - the offspring of the Gods • Rules... [click here for more]
In memoriam: Boris Strugatsky (1933-2012)
In the Zones, the laws of nature have gone insane. Deadly anomalies defy logic and reason. Monsters roam the streets of dead cities and the bones of the fallen crack beneath your feet. No one knows what really happened, nor do they really care. The World wants the Zones closed off, walled in and forgotten. The governments ... [click here for more]
Vampire: The Masquerade exploded into hobby games in 1991 and inspired a generation of fans of which the game industry had never seen before or since. The cultural significance Vampire left on not just the gaming world but on modern vampire-related pop culture can be seen and felt at virtually every turn and in every medium today. Vampire: The Masquerade - 20th Anniversary Edit... [click here for more]


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Stanley: Is secession bid more than rage?
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Clean & Simple with FlyLady
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Morning Routine:
1. Get up before your family.
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7. Eat something good for you and take your medicine and vitamins
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9. Complete the daily task posted on the weekly thread.
At the end of the day complete your evening routine:
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The List
Low-cost cars are often boxy on the outside, bland on the inside and boring to drive – but here's a look at five inexpensive 2013s that break the mold in Kelley Blue Book's 11th annual "Coolest New Cars Under $18,000 list":
- Fifth-coolest: Dodge Dart (fair purchase price of $15,957). Famous during the 1960s and '70s as an inexpensive-but-reliable small car, the Dodge Dart has returned to Chrysler's lineup for the first time in 37 years as a sporty sedan.
- Fourth-coolest: Honda Fit (fair purchase price of $15,461). This tiny hatchback offers big volumes of passenger and cargo space, not to mention lots of fun on the roadway.
- Third-coolest: Kia Soul (fair purchase price of $14,222). The youth-oriented Soul features an uber-boxy look that's popular with Gen Y, coupled with a hip interior that includes special colored lights that pulse in time to whatever you're listening to on the stereo.
- Second-coolest: Ford Focus sedan (fair purchase price of $15,904). The sedan features an impressive 160-horsepower engine that offers 28 mpg/city and 38 mpg/highway when outfitted with automatic transmission.
- Coolest 2013: Hyundai Veloster (fair purchase price of $17,328). The sporty Veloster shows how far Hyundai has come from the days when it only made boring budget models such as the Excel. The Veloster features a one-of-a-kind design: two front doors and a rear door on the passenger's side only.
-- The Street
Number to Know
80 percent. That's the amount of workers in the U.S. ages 18 to 34 who believe they are "job ready and possess all the skills, experience and education needed to advance in their desired career path or obtain their next job," according to analysis by Bryant & Stratton College with help from a Wakefield Research study. At perhaps a bad time in U.S. employment, it seems there's a "perception gap" between what workers think they're worth on the job and how employers see them, as 40 percent of U.S. employers say most entry-level job candidates lack even the basic skills needed to fill job openings.
-- The Street
Tech Talk
Instagram fired a huge shot with its announcement of "The Death of Vine," but as the video advertising market continues to grow, with industry analysis suggesting it's growing at a 25 percent annual clip, Vine will no doubt be a major player for years to come. As one of the top five apps on Apple's App Store, Vine has 13 million users and is growing at a frenetic pace. Vine users are now producing at least 1 million video clips per day, research firm Simply Measured noted. However, Vine still has a long way to go to catch up to Instagram in terms of users, and engagement. Instagram has 130 million monthly active users – 10 times what Vine reportedly has.
-- The Street


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The distance a building must be from the street as required by zoning laws. For example, if the zoning calls for a 10 foot setback, there must be at least 10 feet between the street and any house or building.
Definition from Nolo's Plain-English Law Dictionary
The distance between a property boundary and a building. Local zoning laws usually require minimum setbacks.
Definition provided by Nolo's Plain-English Law Dictionary.
August 19, 2010, 5:24 pm


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Ovarian Cancer
Ovarian cancer is the growth of cancer cells in the ovaries. The ovaries make eggs for reproduction and female hormones. The most common type of ovarian cancer is epithelial.
Cancer occurs when cells in the body divide without control or order. If cells keep dividing uncontrollably, a mass of tissue forms. This is called a growth or tumor. The term cancer refers to malignant tumors. They can invade nearby tissue and spread to other parts of the body.
Many of these tumors may grow to be very large without showing symptoms. These tumors can be hard to find during a physical exam. As a result, about 70% of patients are found with advanced disease.
Germ cell tumors come from the reproductive tissue. They account for 20% of tumors. Stromal cancers are more rare. These come from the connective cells of the ovary. They typically make hormones that cause symptoms.
Cancerous Mass in the Left Ovary
Copyright © Nucleus Medical Media, Inc.
Last reviewedSeptember 2012by Igor Puzanov, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.


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The price you see is the price you pay.
Schustergasse 18 Darmstadt, Germany
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This program explores the world's diverse
cultures, visual heritages and art scenes
throughout history. Faculty research
focuses on Europe, Africa, South Asia,
the Middle East and Canada. It brings a variety of interdisciplinary perspectives to bear on subjects ranging from the Islamic World to Ghana's Ashanti Region, early visual representations of the Okanagan Valley to Surrealist art and film.
This program gives students opportunities
to study literature and literary criticism and
bring lessons learned from that study into
their own writing. Creative Writing hosts
many visiting author readings each year
in order to expose students to a variety
of contemporary writing. In this intimate
learning community, students are
encouraged to hone their skills by
exploring a variety of genres, including fiction, poetry, drama and non-fiction.
This program is distinct in Canada for how it approaches questions of identity, power and justice from an intercultural and global perspective. Cultural Studies combines courses from a variety of Humanities and Social Science disciplines, including pop culture, anthropology, literature and gender studies. The program is organized into three related streams: Media and Popular Cultures; Global Cultural Studies; and Critical and Cultural Theory.
Through literature, this program focuses on questions of genre and gender, issues of voice, identity and radical uncertainty. Students examine how literature imparts meaning in multiple contexts, throughout history and in the contemporary globalized world. Courses range from composition to Renaissance Studies, Contemporary Poetics to Canadian, Indigenous and Postcolonial literatures, to studies in the emerging field of digital humanities.
Whether you're new to the language or have advanced language skills, French Studies can lead to excellent opportunities in Canada and the Francophone world. Program courses provide a basis in French language skills and opportunities to explore French literature and culture in Canadian, global, contemporary and historical contexts. Options in the French Studies program include study abroad and student exchanges with France.
This program offers artists a unique combination of courses in performance practice, visual arts, and creative writing. Interdisciplinary Performance provides training in movement and voice, ensemble work, improvisation, collaborative and solo performance creation. Course offerings include a wide range of artistic media such as video art, film, photography, painting, sculpture and installation.
Spanish Studies offers a comprehensive learning experience immersed in one of
the world's most widely spoken languages. In addition to language skills, students develop an understanding of the diverse literatures and cultures of Spain and Latin America. Linguistics study develops understanding of the relationship between language and culture. Program options include study abroad in Spanish-speaking environments.
This program balances academic study
and studio work, and it provides a critical
and contemporary art education. Students
acquire the foundation skills and theories
to work in a variety of media, such as
drawing, painting, sculpture, printmaking,
photography and digital documentary
production. Integral to Visual Arts are innovative academic electives, visiting artist workshops and opportunities to participate in myriad art exhibitions.


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Repair photoshop software: Adobe Photoshop tutorial, Repair damaged photoshop images with psd tool, repair corrupt Photoshop(PSD,PDD) image files and more.
Related popular searches: repair photoshop cs, photoshop cs repair, photoshop photo repair, photo repair in photoshop, repair photoshop file
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Cost: $149.95US | Developer: Photoshop PSD Repair | ||||
Photoshop psd repair software is featured with advance algorithm that offers high scanning of storage media to recover PSD and PDD files in every possible dataloss situation. There is no need to worry about lost images from photoshop because now there is an effective tool to recover and repair deleted or damaged images from photoshop. You can also recover separate layers with this tool. For more info: http://www.photoshoppsdrepair.com |
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PhotoshRecovery is a powerful data recovery software for damaged Adobe Photoshop image files (.PSD,.PDD). Recovered layers are saved in Windows Bitmap format (.BMP). Original dimensions and color depth are recovered for each layer, as well as color palette. Easy-to-use tool, no special user skills required. |
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Advanced PSD Repair(APSR) is a powerful tool to recover corrupt Photoshop image(PSD, PDD) files. It uses advanced technologies to scan the corrupt or damaged Photoshop image files and recover your data in them as much as possible, so to minimize the loss in file corruption. Currently APSR supports to recover PSD and PDD image files produced by all versions of Adobe Photoshop. |
file size: 662k | Keywords: Recover, backup, fix, gif, picture |
Recent searches:


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Where should I send the Downloads?
I Will Teach You To Be Rich
From the monthly archives:
February 27, 2013 · 4 comments
February 24, 2013 · 13 comments
February 21, 2013 · 18 comments
February 18, 2013 · 20 comments
"Smart, bold, and practical. I Will Teach You to Be Rich is packed with tips that actually work." —J.D. Roth, Get Rich Slowly
Buy now from Amazon
Buy now from B&N
Ramit's tested, proven tips have saved people thousands of dollars. Get a free 7 day starter course and start saving.
Ramit gathered the most successful freelancers in the world to teach you how to earn thousands of dollars doing side jobs.


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- News Date: (12/19/2013) 1). New Customers ......VSI Welcomes... Summit Park District, IL Talbot County P&R, Easton, MD (December 2013) Park City, UT (December, 2013) Collinsville, IL (December, 2013) Foster City, CA (November 2013) Kettering He...... Updated: (12/19/2013) Created: (12/19/2013)
- News Date: (11/27/2013) 2). Congrats Mike Poulin: 20yrs at VSI ......VSI congratulates Mike Poulin on 20 years of service with the company! It is hard to believe that 20 years have passed since we hired Mike to be our lead installation specialist for our first round of...... Updated: (11/27/2013) Created: (11/27/2013)
- News Date: (09/16/2013) 3). Congrats Phyllis Willey: 20yrs at VSI ......VSI congratulates Phyllis Willey on her 20 years of service to the company! Over the years Phyllis has worked in Customer Support and Documentation, and she currently is one of the "quiet cogs" in Dev...... Updated: (09/16/2013) Created: (09/16/2013)
- News Date: (08/07/2013) 4). Congrats John Willey: 20yrs at VSI ......The newest member of the VSI "20 Year Club" is John Willey, who is our VP of Sales. John started his tenure at VSI doing installation and training. He migrated to sales after a few years to match his ...... Updated: (09/16/2013) Created: (08/07/2013)


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Dethro Starkiller: looks great! Cant wait to mingle with the bothan model *wink* (lol)
Dethro Starkiller: looks great! Cant wait to mingle with the bothan model *wink* (lol)
Great Job Summer, Fraco, Yuna, Liletha, Missily, Starri, and everyone else
Last edited by EkeCib; 12-09-2012 at 04:51 AM.
Here is a recording of the entire event. Thanks Fiirefly for making all of this happen and Fraco for the music.
Really awesome work to everyone involved! Very enjoyable, and it was a great event. The preformance was really well done! Thank you!
thanky for the video, a real show. congrats to the hosts and actors. this looked full of life!
Mortekai is stylin' on you!!!!!!!
<CULT> Overlord
Thanks for this awesome event! And the music on the radio.. 5 stars!
Great job, guys. It was so nice to see so many people out as well.
There are currently 1 users browsing this thread. (0 members and 1 guests)


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December 6th UK Releases and Bargains
As December begins, the only releases of note this week are for the PS3, and for the 3DS On the deals side of things it's also pretty quiet, from SimplyGames you can get for the PC for £19.99... more
As December begins, the only releases of note this week are for the PS3, and for the 3DS On the deals side of things it's also pretty quiet, from SimplyGames you can get for the PC for £19.99... more
Whew! Started feeling really rotten there at the end of the "break". Had too much going on in my personal life to spend a proper time on Sprout's Tale, but we're back now and, dare I say, with a ... more
Anyone who follows professional wrestling is most likely aware of something simply called "The Streak". It's in direct reference to The Undertaker's undefeated streak at WrestleMania, the Super... more
If you like being happy, Tearaway is for you. No, really. I was climbing a mountain and it was cold, and I couldn't go on until I made myself some mittens. I cut them out of construction paper ... more
Today on the Smash Bros website/Miiverse, Mr. Sakurai revealed Skull Kid in his triumphant return! Well, that quote is a bit of a disappointment for some people, but I think the Kid works muc... more
The new blog of my rough translation of the latest Famitsu article is up! I'm still making some minor adjustments to this one, but I hope it's starting to look more like a decent blog should look... more
Allright fellas - 2013 is almost up, so it's time for the usual list. I know I'm lagging behind on my censorship blog, but I just moved, so I was busy a bit and this thing will be short and effec... more
Remember your first time? The first time you took the thing out and put it into the designated slot to have some fun? The first time you went on for an entire night without taking a 15 minute bre... more
Hey everyone! Guess who should be studying his ass off for competition law? Thats right, me! Guess who ISNT studying his ass off right about now? Yup, me as well. So why would a total honorstu... more
Hi, while i am posting comments very often since around 4 or 5 months now on dtoid, the blog is a very new thing for me. After the rant which got over 100 comments in less than a day and a revie... more
I wasn't much heavily invested in The Walking Dead Telltale game. I felt that I needed to watch the show in parallel to gain the most out of the game's experience, but the show was just not doing... more
I was playing Bioshock recently when I something suddenly stuck out to me. Rapture has not a single black resident. Now, this sort of thing can be hand waved. Ayn Rand.. .. sorry, Andrew Ryan, wa... more
Last week I got a Nexus 7 and talked about it. I got it to meet basic computing needs my laptop was no longer meeting. I thought that by getting this I would have to delay my conquest of and un... more
-*-*-*-*-*-*-R . A . N . T . . . . I . N . C . O . M . I . N . G-*-*-*-*-*-*- So, there's been people bitching and complaining about community. People bitching and complaining about Dtoid los... more
(, , and are here, if you need to catch up.) Does this game even an introduction? It's freakin' Starcraft: Part Deux. Remember when Blizzard first revealed this? After years a... more
Ever since I started blogging here around the beginning of the year, I've been thinking I should keep away from talking about personal drama or struggles for the sake of my own (joyful)sanity. F... more
The Wii was my favorite console the last generation. That's not a ridiculous proposition if you think about all the first party successes the platform had with Mario, Zelda, Donkey Kong, and o... more
Ohai Dtoid. It's me. The zombie who is et cetera. You might be asking yourself a question such as: Hey, self... Zombie Orwell is great. Well, that's technically not a question, you filthy perve... more
As an old guy (33) who plays since around 1987 i thought its just fitting if i write about some of the older games i played and enjoyed..or hated..because their difficulty..unfairness or just ... more
Weekly Pokemon update: I've been diving into Battle Spot, which is essentially unranked matches. 6 versus 6 is the way to go and this is why I hate Battle Spot and its 3 v 3 rule set. 6 v 6 at l... more
With just around the corner, Massive Entertainment has released a new teaser trailer for If this doesn't peak your interest about what is to come with this year's Next-Gen-focused show, watch... more
It was around 2:00 am this morning during crackedbat's regular aerosol and Olde English 800 binge when an ad caught his attention. It was an ad for yoga pants that look like jeans. After he was d... more
I thought some of you guys might be into this. If you're one of the first 250,000 people to visit DHL.net and register for an account and they'll send you an email containing a steam key for Encl... more
If gender swapping was like , there would be a lot more dead bodies in the world. more
I am a terrible Killer Instinct player. It's not the game that is at fault. It's fairly simple to learn, not incredibly challenging to master. It's responsive, fluid, and well designed. No, i... more
What do mages, wizards and witches do, outside of being magic users? No really, what do they do? Theres never an explanation as to why theyre learning magic, what theyre planning to do with th... more
L1XSl5GTolE Hoping to make this into a youtube series more
After a lot of video ads with sound..sometimes even unstoppable sound i mentioned it in the comment section last week..some people recommended me adblock or noscript solutions. As a website own... more
It's December. You know what that means. December has always been a favorite month of mine, mostly because I was a spoiled only child growing up. My parents made sure that gifts with my name on ... more
YOU ARE A GODDAMNED CYBORG NINJA WITH A HIGH FREQUENCY KATANA THAT CAN CUT ANYTHING FIGHTING AGAINST A GIANT FUCKING ROBOT IN THE MIDDLE OF THE CITY YOU THROW THE GIGANTIC ROBOT INTO THE AIR, FOL... more


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Veliparib With or Without Mitomycin C in Treating Patients With Metastatic, Unresectable, or Recurrent Solid Tumors
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
ABT-888 (veliparib) may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as mitomycin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving ABT-888 together with mitomycin may kill more tumor cells. This phase I trial is studying the side effects and best dose of ABT-888 when given with or without mitomycin in treating patients with metastatic, unresectable, or recurrent solid tumors.
Condition | Intervention | Phase |
Unspecified Adult Solid Tumor, Protocol Specific |
Drug: veliparib Drug: mitomycin C Other: laboratory biomarker analysis |
Phase 1 |
Study Type: | Interventional |
Study Design: | Allocation: Non-Randomized Endpoint Classification: Safety Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | ABT-888 as Monotherapy and in Combination With Mitomycin C in Patients With Solid Tumors With Deficiency in Homologous Recombination Repair |
- Feasibility of screening for Fanconi anemia (FA) deficiency across different tumor types, and that patients deficient in this pathway (no FancD2 foci formation in their tumors) exist in adequate number to justify further trials [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
- Ability to safely deliver ABT-888 in a continuous dose as monotherapy [ Time Frame: Up to 3 years ] [ Designated as safety issue: Yes ]
- Ability to safely deliver the combination of mitomycin C and ABT-888 [ Time Frame: Up to 3 years ] [ Designated as safety issue: Yes ]
- Selection of a dose schedule of ABT-888 monotherapy and the combination of mitomycin C and ABT-888 for phase II trials [ Time Frame: Up to 3 years ] [ Designated as safety issue: Yes ]
- FancD2 foci formation in peripheral blood mononuclear cells [ Time Frame: Week 1 and 5 ] [ Designated as safety issue: No ]
- BRCA mutations [ Time Frame: Baseline ] [ Designated as safety issue: No ]
- Foci produced by the histone variant γH2AX [ Time Frame: Week 1 and 5 ] [ Designated as safety issue: No ]
- Tumor shrinkage as assessed by radiology [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
Estimated Enrollment: | 75 |
Study Start Date: | October 2009 |
Estimated Primary Completion Date: | June 2014 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Group I (veliparib)
Patients receive ABT-888 PO BID in the absence of disease progression or unacceptable toxicity.
Drug: veliparib
Given PO
Other Name: ABT-888
Other: laboratory biomarker analysis
Correlative studies
Experimental: Group II (veliparib and mitomycin C)
Patients receive ABT-888 PO BID on days 1-7, 1-14, 1-21, or 1-28. Patients also receive mitomycin C IV over 10-20 minutes on day 1. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Drug: veliparib
Given PO
Other Name: ABT-888
Drug: mitomycin C
Given IV
Other Names:
Other: laboratory biomarker analysis
Correlative studies
Detailed Description:
I. To screen cancer patients across different histological sites to identify those with functional defects in the Fanconi anemia (FA) pathway in their tumors.
II. To establish the safety and practicality of treating patients with FA-deficient tumors with the PARP inhibitor ABT-888 as protracted monotherapy.
III. To establish the safety and practicality of treating patients with FA-deficient tumors with the combination of mitomycin C and ABT-888.
IV. To select a dose of ABT-888 protracted monotherapy and a dose-schedule of the combination of mitomycin C and ABT-888 in patients with FA deficient tumors for phase 2 trials.
I. To evaluate for germ line FA-repair deficiency and BRCA mutations in peripheral blood mononuclear cell (PBMC) in patients receiving ABT-888 treatment.
II. To evaluate in PBMC samples for foci produced by the histone variant gamma-H2AX in patients receiving Mitomycin C with or without ABT-888 in order to assess any possible effect of ABT-888 in the cellular sensing and processing of Mitomycin C-induced DNA double strand breaks.
III. Quantify the number of patients with antitumor responses.
OUTLINE: This is a dose-escalation study of ABT-888. Patients are assigned to 1 of 2 treatment groups.
GROUP I: Patients receive ABT-888 orally (PO) twice daily (BID) in the absence of disease progression or unacceptable toxicity.
GROUP II: Patients receive ABT-888 PO BID on days 1-7, 1-14, 1-21, or 1-28. Patients also receive mitomycin C intravenously (IV) over 10-20 minutes on day 1. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Blood and tissue samples are collected periodically for further laboratory analysis, including BRCA mutation analysis and H2AX and FancD2 activation analysis.
After completion of study treatment, patients are followed up for 12 weeks.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Histologically confirmed solid tumor malignancy for which no curative or standard therapy exists or for which standard therapy is no longer effective
- Metastatic, unresectable, or recurrent disease
- Tumor demonstrates deficiency for the Fanconi anemia pathway, based on FATSI immunofluorescence screening
Up to two chemotherapy regimens for metastatic disease are allowed; in addition, prior adjuvant/neo- adjuvant chemotherapy, hormonal therapy, molecular targeted therapy or Erb inhibitor treatments (e.g., erlotinib, herceptin, sorafenib, sunitinib) will be allowed and will not count towards eligibility
- At least 4 weeks must elapse since prior chemotherapy or radiation therapy (two weeks for erlotinib, hormonal therapy, or limited field palliative radiation to bone, brain, or radiosurgery), 6 weeks if the last regimen included nitrosureas or Mitomycin C
- Given the association of cumulative doses of Mitomycin C with toxicity, previous use of Mitomycin C would be restricted to topical applications (bladder cancer) or chemoembolization (e.g., liver tumors)
- Eastern Cooperation Oncology Group (ECOG) performance status (PS) =< 2 OR Karnofsky >= 60%
- Life expectancy > 3 months
- Leukocytes >= 3,000/mcL
- Absolute neutrophil count (ANC) >= 1,500/mcL
- Hemoglobin >= 9 g/dL
- Platelet count >= 100,000/mcL
- Total bilirubin within normal institutional limit
- Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x institutional upper limit of normal
- Creatinine within normal institutional limit OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
- The effects of ABT-888 on the developing human fetus are unknown, and Mitomycin C could be harmful to the fetus; for this reason, women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation; should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately
- Ability to understand and the willingness to sign a written informed consent document
- Fertile patients must use effective contraception
- Able to swallow capsules
Ten additional evaluable patients will be accrued to the Arm 2 (MMC + ABT-888) therapeutic portion of the study, once the MTD and recommended phase 2 of the study has been defined; eligibility for these patients includes the following:
- Diagnosis of colorectal malignancy
- Absence of FANCD2 foci by FATSI screening
- Presence of biopsiable lesion by imaging
- Consent to a baseline (prior to treatment) tumor biopsy and for a repeat biopsy at the time of progression on the event that an antitumor response is demonstrated on the MMC-ABT-888 regimen
- Same eligibility as above, except that they will have no limitations related prior number of chemotherapy regimens given; patients could have received prior treatment with PARP inhibitors if used as single agent
Exclusion Criteria:
- Patients may not be receiving any other investigational agents
- Patients with known central nervous system (CNS) metastases (unless previously resected or irradiated and not clinically active) should be excluded from this clinical trial because of their poor prognosis and because they often develop progressive neurologic dysfunction that would confound the evaluation of neurologic and other adverse events; patients with CNS metastases must be stable after therapy for > 3 months and off steroid treatment prior to study enrollment
- History of allergic reactions attributed to compounds of similar chemical or biologic composition as ABT-888 or Mitomycin C
- Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- Pregnant women are excluded from this study because ABT-888 and Mitomycin C are agents with the potential for teratogenic or abortifacient effects; because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with ABT-888 and Mitomycin, breastfeeding should be discontinued
- Human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions or increased risk of lethal infections when treated with marrow-suppressive therapy; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicated
- Patients with active seizure or a history of seizures
- Patients previously treated with poly ADP-ribose polymerase (PARP) inhibitors; with the exception of patients enrolled on Arm 2 who may have had prior treatment with PARP inhibitors as monotherapy
United States, District of Columbia | |
Lombardi Comprehensive Cancer Center at Georgetown University | Recruiting |
Washington, District of Columbia, United States, 20057 | |
Contact: John L. Marshall 202-687-6459 firstname.lastname@example.com | |
Principal Investigator: John L. Marshall | |
United States, Ohio | |
Ohio State University Medical Center | Recruiting |
Columbus, Ohio, United States, 43210 | |
Contact: Miguel A. Villalona-Calero 614-293-9424 email@example.com | |
Principal Investigator: Miguel A. Villalona-Calero |
Principal Investigator: | Miguel Villalona-Calero | Ohio State University |
No publications provided
Responsible Party: | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT01017640 History of Changes |
Other Study ID Numbers: | NCI-2012-01473, NCI-2012-01473, OSU-09100, CDR0000656393, OSU 09100, 8472, N01CM00070 |
Study First Received: | November 19, 2009 |
Last Updated: | December 6, 2013 |
Health Authority: | United States: Food and Drug Administration |
Additional relevant MeSH terms:
Neoplasms Mitomycins Mitomycin Antibiotics, Antineoplastic Antineoplastic Agents Therapeutic Uses |
Pharmacologic Actions Nucleic Acid Synthesis Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Alkylating Agents |
ClinicalTrials.gov processed this record on December 12, 2013


text:
iPhone & iPad Live 294: 7-inch iPad, 4-inch iPhone, iOS 6 Maps
Georgia, Seth, and Rene discuss all the latest Apple rumors, including the 7-inch iPad, 4-inch iPhone, iOS 6 Maps, and Apple wanting to hurt Google in the wallet. Also, free iPad games, Sparrow push, Chrome for iOS, and the pro stylus shootout!
Brought to you by Audible. Please visit http://www.audiblepodcast.com/imore for your free audiobook download! And thank you for supporting our sponsors!
- Subscribe via iTunes: Audio | Video
- Subscribe via RSS: Audio | Video
- Download directly: Audio | Video
- 7-inch iPad on track for October 2012 release, $200 to $250 price
- iPhone 5 to be another Google killer -- but with a twist
- iPhone 5 design still not finalized, still no big screen, still no metal back, still on track for October release
- Apple rumored to increase iPhone screen size to 4-inches
- The 4 inch iPhone
- iOS 6 reportedly code named Sundance, more rumors about Siri API, Siri for iPad, iTunes 11
- Apple rumored to be adding photo and video sharing, commenting features to iCloud
- Best free iPad games
- Did you hear the one about Chrome for iOS?
- Sparrow for iPhone updated: push coming soon as yearly subscription
How to
- Georgia (GeorgiaTiPb
- Seth Clifford (@sethclifford)
- Rene Ritchie (@reneritchie)
You can reach all of us on Twitter @iMore, or you can email us at email@example.com
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There are 5 comments. Add yours.
Just curious if you go out of your way to get the worst possible shot of each of you for the screen cap of the podcast?
I agree Gary, the play button is blocking the shot but it sure looks like Georgia is picking her nose. I won't ask if you found what you were looking for.
Great screen capture this week....Seth looks disinterested, Georgia is picking her nose and Rene is sleeping....must have been one heck of an episode!!!
I wonder if Rene is moving away from his original prediction the screen won't change in size or it will be very insignificant.


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BEST Robotics
BEST Robotics is a middle-school and high-school competition that engages students in the study of engineering, science, and technology as they create remote-controlled robots. Applying Model-Based Design with the VEX Cortex Microcontroller and Simulink lets your team efficiently design and build a functioning machine for your BEST Robotics mission.
2013 BEST Robotics Kickoff: Simulink Support for VEX 7:12
Design and build a program for your BEST Robot using Simulink® and the new Simulink support features offered for VEX Cortex® Microcontroller.
Get started with these resources for learning and classroom instruction, and explore the MATLAB and Simulink products available for this competition.
SoftwareTutorialsAdditional Resources |
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Definición de hopefully in Inglés
The traditional sense of hopefully, 'in a hopeful manner', has been used since the 17th century. In the second half of the 20th century a new use as a sentence adverb became established, meaning 'it is to be hoped that', as in hopefully, we'll see you tomorrow. This second use is now very much commoner than the first use, but it is still believed by some people to be incorrect. Why should this be? People do not criticize other sentence adverbs, e.g. sadly (as in sadly, her father died last year) or fortunately (as in fortunately, he recovered). Part of the reason is that hopefully is a rather odd sentence adverb: while many others, such as sadly, regrettably, and clearly, may be paraphrased as 'it is sad/regrettable/clear that ...', this is not possible with hopefully. Nevertheless, it is clear that use of hopefully has become a shibboleth of 'correctness' in the language—even if the arguments on which this is based are not particularly strong—and it is wise to be aware of this in formal contexts.


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Game of Thrones Greyjoy Keychain
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The Greyjoys of Pyke claim descent from the Grey King of the Age of Heroes. Known for their fierceness in battle, the Iron Kings of Greyjoy ruled far beyond their island lands, carving kingdoms in the mainland with fire and sword. The Greyjoy sigil is a golden kraken upon a field of black. Their words are We Do Not Sow. Show your allegiance with the Game of Thrones Greyjoy Keychain!
- Keychain is in the shape of a shield with the Greyjoy sigil featured on the front


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1972 Buick Electra 225. Great car with a clear title. The car is in really good condition, the interior and dash is in mint condition... More
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1962 Buick Electra 225 Desirable 4dr Hard Top. Only 53k actual documented miles, all original, gorgeous original (Fawn mist code) finish. Stunning original matching... More
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This beautiful Electra 225 was Buick's top of the line luxury car of 1965. This car is loaded with all power options including rare... More
Engine: Wildcat V8 Transmission: Automatic Mileage: 69895 Actual Miles Exterior Color: White with White Convertible Top Interior Color: Red Exterior Condition: Excellent Interior Condition: Excellent Long-Term Buick Dealer/Collector Owned Roll Out... More
Outstanding example with 65,000 miles. Gorgeous original interior. 425 nailhead V8, auto, ps, pb, pw factory a/c, must see and drive! A real beauty! SELLING... More
Buick marked a year of finals in 1970. This was the final year Buick would offer the Electra convertible, finned aluminum brake drums, and... More
1970 Buick Electra 225 Convertible, I've owned this car for 10 years. It was originally from Kansas and is a very solid car. All... More
1961 Buick Electra 225 Convertible, Older frame-up restoration that won Senior Gold at Buick Nationals in 1995. Award winner at many shows. It has been maintained... More
1978 Buick Electra Park Avenue, 2-Dr Hardtop, 350 Engine. 81,700 miles, Runs good, clean, no body damage or rust. Blue with blue vinyl roof Repainted and vinly roof... More
1970 Buick Electra Convertible, Red with black deluxe interior white top, Rare 455 V8, 370 HP (one year only), power steering power brakes, 6... More
1968 Buick Electra 225 - 4 Door - Hardtop Coupe - 8-cyl. 430cid/360hp One owner. Runs like new. Everything is original except the water pump. Power windows,... More
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BUICK: 1969 Electra 225 Limited 4-door hardtop, rebuilt 430 Wildcat engine, no major rust, California car, fly in, drive home, $7,500; includes delivery USA.... More


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Find your way to the best Volkswagen service center in Greeneville, Tennessee with AutoMD.
Want to make full use of your vehicle's warranty? Then you should know the location of the nearest Volkswagen service center in Greeneville, Tennessee. Luckily, AutoMD has all the info you need about the different auto shops in your state. We can help you locate Volkswagen auto repair shops in no time. All you have to do is provide us with your vehicle's make and your location, and we'll generate a list of auto mechanic centers within your city.
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Buy Tickets An Evening with Joe Wright
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Since making his feature directorial debut in 2005 with the Oscar-nominated take on Pride & Prejudice, Joe Wright has quickly established himself one of the brightest young filmmakers on either side of the Atlantic. We are delighted to welcome him for this special preview screening of his latest, Anna Karenina, followed by an onstage discussion with Wright and Tom Stoppard and an encore screening of Atonement. Read more »


text: CANPATFULL (Canadian Patents FULLtext database) covers the full text (on OCR basis) of patent applications and specifications published in Canada. The records of the database contain bibliographic data including patent applicant, inventor and legal representative information, patent, application and priority application data, IPC, CPC, and EPC classification codes, abstract, and the full text of description and claims. Each database record contains all documents published for one application, displayed in order of appearance. Legal status data, and display formats from the INPADOCDB database are available. Producer: LexisNexis Univentio B.V. Supplier: FIZ Karlsruhe |


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Charlize Theron in a Bikini With Son Jackson | Photos
Charlize Theron Shows Off Her Hot Birthday Bikini Bod
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全景摄影师 Mark Vanstone 日期和时间 12:24, 18/09/2012 - Views |
Upton Cross Anticline Bude |
The beach at Upton Cross near Bude is a favourite spot for geology trips. The rocks in the cliff have been folded into a series of synclines and anticlines. There is also a dextral tear fault exposed in the wave-cut platform.
The view overlooking the beach at Widemouth Bay, one of many beaches on north Cornwall's rugged Atlan...
Widemouth Bay on the North Cornwall coast is a great attraction during the summer forthose wanting la...
The low winter sun breaks past Black Rock on Widemouth Beach on Cornwall's rugged northern Atlantic c...
Millook Haven in north Cornwall is a famous location among geologists because of the chevron folds in...
Europe is generally agreed to be the birthplace of western culture, including such legendary innovations as the democratic nation-state, football and tomato sauce.
The word Europe comes from the Greek goddess Europa, who was kidnapped by Zeus and plunked down on the island of Crete. Europa gradually changed from referring to mainland Greece until it extended finally to include Norway and Russia.
Don't be confused that Europe is called a continent without looking like an island, the way the other continents do. It's okay. The Ural mountains have steadily been there to divide Europe from Asia for the last 250 million years. Russia technically inhabits "Eurasia".
Europe is presently uniting into one political and economic zone with a common currency called the Euro. The European Union originated in 1993 and is now composed of 27 member states. Its headquarters is in Brussels, Belgium.
Do not confuse the EU with the Council of Europe, which has 47 member states and dates to 1949. These two bodies share the same flag, national anthem, and mission of integrating Europe. The headquarters of the Council are located in Strasbourg, France, and it is most famous for its European Court of Human Rights.
In spite of these two bodies, there is still no single Constitution or set of laws applying to all the countries of Europe. Debate rages over the role of the EU in regards to national sovereignty. As of January 2009, the Lisbon Treaty is the closest thing to a European Constitution, yet it has not been approved by all the EU states.
Text by Steve Smith.


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We are looking at ways to engage more members of the global community. We would like to know how you feel about using the United Nations The... Read more.
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Throughout the Teachers Engage Community there are incentivized discussions for fabulous prizes. Each discussion clearly states when participation in the discussion thread will count for a drawing entry. After the drawing period the discussion and resources are still available for participation and sharing.
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Queen Anne's Lace Earrings
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Bringing new life to a medieval crafting technique, French designer L'Orina finely tats cotton thread to create her intricate, lace-like framework of loops and pearls. Hook closure. Silver, glass pearls, cotton. 2.4"L. Handmade in France.
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Mr. Bunyan offered a resolution to change the hour of daily meeting from ten to nine o'clock A.M.,
It lies on the table one day under the rules.
Mr. Banyan gave notice of his intention to call it up to-morrow.
Mr. Collett offered a resolution directing the Attorney General to report his opinion as te whether a woman is eligible to the office of State Librarian. Adopted.
Mr. Rhodes offered a concurrent resolution, requesting Indiana Congressmen to urge the passage of a law regulating railroad tariff.
Mr. Harney understood that Congress has no power to legislate in this way, and was opposed to anything looking to the enlargement of Federal authority in this direction.
Mr. Rhodes knew the people of the West are very much agitated on the subject of railroad freights, and he regarded it as a matter proper for Congressional interference.
Mr. Scott thought the resolution should not be passed in the present form. The State is capable of regulating domestic traffic without the interference of Congress. He moved the reference of the resolution to the Committee on Railroads.
Mr. Harney believed Congressional interference, even if it should be had, would be decidedly against the West. Agreed to.


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Guys, press and hold the frame rate button and a new menu that allows custom frame rates will be displayed. You can currently go as low as 1fps. The contextual menues show 8fps as the lowest w/o HDRx and 6fps with HDRx.
Anyway, I don't know why anyone gets in a panic over what people chose to do what. Personally I like the Scarlet for time-laps over my 7d.


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Nov 27, 2012, 09:34 PM | #1 |
Tracking lost/stolen iPhone
So I'm trying to help a friend of mine who's iPhone is believed to be stolen.
I called Apple and asked if there is any way they can track/flag down the iPhone if someone ever tries to activate it. Of course, they said no and what should have been done was to install Find my iPhone app and sync it with iCloud. Then the AppleCare guy I spoke to of course tells me that what could have been done is wipe the iPhone for security but didn't say anything about actually retrieving the iPhone. In the end, I was told to look at other options in order to try to get my friend's iPhone back. So my next move is to try with the carrier to see if they can possibly flag this particular iPhone if someone ever tries to activate it. Is this something they can do? Thanks. |
0 |
Nov 27, 2012, 09:49 PM | #2 |
All these posts are so stupid. How does one STEAL your phone? Like honestly... Just because you forgot your phone somewhere and someone took it that doesn't mean they STOLE it. It means you were stupid enough to lose your phone.
3 |
Nov 27, 2012, 10:05 PM | #3 |
It dosen't mean he stole the phone look for it, you know under the couch in the car seat. Happy hunting
0 |
Nov 27, 2012, 10:31 PM | #4 |
If they didn't have find my iPhone on the phone then your friend is out of luck.
If your friend knows what the imei number is they can report it lost or stolen and the phone will be flagged and not be able to be activated. |
0 |
Nov 27, 2012, 10:39 PM | #5 | |
In your logic, if someone takes your car cause you left it in the parking lot, it's not stealing. |
3 |
Nov 27, 2012, 10:54 PM | #6 | ||||
These two idiotic posts are exactly the reason why I wish MacRumors kept the down vote button. Quote:
Thank you for understanding. ---------- Quote:
Thanks. I'm sure we can get the serial and imei numbers. And that's all I was really hoping for, that is, Apple would help out with notifying her if someone else were to try to activate her stolen iPhone. |
0 |
Nov 27, 2012, 11:41 PM | #7 |
The fundamental problem here is that it's incredibly difficult to recover ANY type of stolen property. If it wasn't, people wouldn't bother to steal things!
Find My iPhone and similar tools are really only good for two things: 1) Finding a device if you know that it's not REALLY lost/stolen (but somewhere like the back of your couch). 2) Erasing the device if it's stolen. Apple could make it so that a blocked iPhone cannot be re-activated, but they don't. The carriers in the US have started to build a combined database where lost/stolen devices are blacklisted across ALL networks, but that's not in full motion yet.
Nexus 5 32GB Black (Three UK) | Nexus 7 (2012) | Kindle Paperwhite (2013) iPhone 4 32GB White MacBook (Late 2007) Windows 8.1 | iCloud, Dropbox, Spotify Premium |
0 |
Nov 28, 2012, 04:01 AM | #8 | |
0 |
Nov 28, 2012, 11:55 AM | #9 |
1 |
Nov 28, 2012, 01:58 PM | #10 |
First of all, Marrakas was completely right. Second, how old are you? 13? His simple logic probably went over your head...
2012 iPhone 5 2012 iPad Air - 128GB WiFi 2011 iMac 27" - 3.4GHz Quad i7, 16GB, 256GB SSD + 2 TB HDD 2011 MacBook Air 13" - 1.8 GHz i7, 4GB, 256 SSD, Carbon Skinned |
1 |
Nov 28, 2012, 02:37 PM | #11 | |
aren't they both someone's property? stealing is not stealing depending on the value of the item? or its portability? or size? just curious how you reason here. |
2 |
Nov 28, 2012, 03:40 PM | #12 |
Those numbers are printed on the label on the back of the box that the iPhone came in.
0 |
Nov 28, 2012, 03:43 PM | #13 |
If you actually READ THE TITLE,you'd see the OP put LOST/stolen iphone. That aside then what exactly are you saying? That something someone else has that wasnt given to them isn't stolen?
0 |
Nov 28, 2012, 06:47 PM | #14 |
You are HAVE to park your car outside you can't take you car inside your room or inside a restaurant It's not like you are leaving your phone behind because that's what you are supposed to do. You made a mistake and now you have to face the consequences.
0 |
Nov 28, 2012, 07:59 PM | #15 |
You have lost all credibility in this argument, so time to let the rest of us enjoy the boards and allow the OP's questions to be answered.
2 |
Nov 28, 2012, 08:22 PM | #16 |
Apple knows exactly where your lost phone is located, they know this because every time you use itunes or any other service of your iphone it send the imei and serial number to their servers.
I think that when you buy a new iphone you should be able to register your iphone in itunes so that if some day it is lost you could contact Apple and they tell you exactly where is located your lost iPhone. An iphone constantly sends all type of information to Apple servers they know the location, the ip, and more information about every iphone out there. Sooner or later everybody needs to connect his iphone to itunes, download updates, download new apps, music, use iCloud, etc, etc, this is where Apple could help owners of an iphone to locate it. Also the find my iPhone was built so that any one could disable that services, if your iphone is stolen they could wipe everything and then you could not find your iPhone, why Apple let people do this, it could be better that you could only delete the information from an iphone if you enter your password. The first thing that thiefs do when they stole an iphone is to turn it off. It could be great that you could only shutdown your iphone if you enter your password to avoid this issue. The last time my iphone 4 was stolen I could not see the last location because they wipe everything, and when some one do this the last location of your device is deleted. It could be nice that you see the last locations of your device also. |
0 |
Nov 29, 2012, 07:01 PM | #17 | ||
That's exactly it, Apple can easily find the location of a lost or stolen device when ever it is used by anyone other than the rightful owner. The question is, will Apple in any way aid in recovering that device? Simply put, no they will not. Quote:
This is exactly what Apple said that could be done if a device has the Find my iPhone app or iCloud syncing enabled. But seriously, why just simply wipe a device if an owner's intention is to recover their property? Don't get me wrong, I can understand wiping the device in the long-term so no one can access the information on it. But if someone wants their stolen property back and it is as easily trackable as Apple products are, Apple should do what they can to help the owner in these cases. |
0 |
Jan 31, 2013, 01:58 PM | #18 | |
---------- how does he lose credibility? both are forms of private property just at different values...you sir should not have dropped out of beauty school
"people like to feed pigeons, but try to shoot eagles" |
0 |
Jan 31, 2013, 02:05 PM | #19 |
Honestly, who cares about this whole side of the discussion?! It's not what the original question and the thread is about. Time to let go of this off-topic and irrelevant (and unfortunately ultimately mostly flaming/trolling) discussion and stick to something useful.
1 |
Feb 1, 2013, 08:44 PM | #20 | |||
*sigh* Kids should be banned from the internet. |
1 |
Feb 1, 2013, 09:15 PM | #21 |
You were the first to call names..... Your friend is dumb for not having find my phone.
For all of you comparing someone picking up a phone they found sitting on a park bench to actually breaking into a car and taking it are silly. Yes they are both stealing (if the phone is picked up for the purpose of keeping it) but come on, not even in the same park. OP you also want apple and others to jump through hoops to help your friend (or anyone that has lost/stolen iPhone) but how/why is that their job? How is it their job to blacklist a device? How do they know it's stolen? What's to keep you from selling your phone then calling and saying it was stolen? I say hold on to your expensive items and don't "lose" them. Practice by prevention.... tell your buddy to give it a shot. Last edited by AFDoc; Feb 2, 2013 at 01:17 AM. |
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Feb 1, 2013, 10:15 PM | #22 | |
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Feb 2, 2013, 07:40 PM | #23 |
If it's stolen, your only option is to;
1) Find IMEI on Box, contact your carrier to get it blocked. 2) File a complaint with the police. 3) Hope that you have insurance. Two of my friends in the last 6 months have had their phone taken from their pocket, one on a street and another at a bar. Both unaware until 5-10 minutes later when they've gone to grab their iPhone's. Luckily both had insurance. Even if you had the Find my iPhone app, there's not much you could of done. They would of most likely turned the phone off, by the time they've turned it on, I would hope anybody with common sense would just get it IMEI blocked so it becomes a brick to them.
Twitter: @Shorty
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