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Cruise Lines
Norwegian Cruise Line
About Your Ship: Norwegian Pearl
About Your Ship: Norwegian Pearl
Expert Review:
Not Yet Rated.
Departs Vancouver (Canada Place)
Norwegian Cruise Line
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Overview & Itinerary
Deck Plans
Food & Dining
Entertainment & Activities
Photo Gallery
Expert Review
Customer Reviews (53)
See Prices & Availability
Read Below About:
Fitness and Recreation
Dress Code
Public Rooms
Fellow Passengers
Overall Rating
About Cruise Critic Star Ratings
Standard cabins are comfortable and well laid-out, and with adequate closets and drawer space for most families, they're cozy.
All have mini-fridges, flat-screen televisions, telephone, Internet connection, bathrooms with shower and twin beds that can be made up as queens. But, at an average size of 160 square ft. for the outsides and 145 for inside staterooms, they are among the industry's smallest -- especially for a newly built vessel -- and especially for a line aiming for families. Balcony cabins are 205 square ft., which includes the verandah. All but some inside cabins have a "split bathroom" configuration: glass-enclosed shower on one side, closeable toilet chamber on the other, sink in the middle. Balcony cabins also have a small sofa, many of which can be made into a third bunk.
Compared to some of the slab-like beds found elsewhere on NCL, the bedding has been upgraded on this ship, with thick, comfy Eurostyle mattresses. Instead of a bedspread, beds are made with white duvets and a small colorful "runner" placed across the foot.
Our absolute favorite attribute of any cabin on an NCL ship is the in-cabin coffee/tea makers thoughtfully provided to the guests, along with complementary coffee, tea, hot chocolate and cream.
Where Pearl really stands out is in its suites. The 134 mini-suites offer, at 284 square ft., a small amount of additional space and a larger balcony, have full bath tubs and the services of the concierge. Beyond those, though, guests who are booked into Romance Suites, Penthouse Suites, Courtyard Villas, Owners Suites or Garden Villas enter the stratosphere of cruisedom, with private restaurant privileges, butlers, individual espresso and cappuccino makers, preferred reservations for the alternate restaurants, VIP tender access, VIP boarding and disembarking, a DVD library and other perks and privileges that truly set them apart from the average guest on the same ship.
The Courtyard Villas share a private courtyard at the top of the ship, complete with a covered plunge pool and private hot tubs. Owners Suites, typically located beneath the bridge, face forward and, since they are at the corners of the bow, have private sundecks both at the front and along the side. The Garden Villas, smaller on this ship than on Dawn, Jewel or Star, where they come in at an astronomical 5,700 square ft., nonetheless still measure 4,390 square ft., have individual saunas, hot tubs, private sunbathing areas and three bedrooms, three baths, a powder room, living room, dining room, a grand piano, and exclusive elevator access to their quarters, shared only with the residents of the Courtyard Villas and two Deluxe Owner's Suites located at the very, very top of the ship.
Caveat: The Owners Suites and Penthouse Suites on Deck 10 have verandahs that are completely visible from the bridge above. Completely. Any indiscretion that takes place out there is subject to being viewed by a range of officers -- or any visitors to the bridge.
Some of the 24 Penthouse Suites, at up to 572 square ft., on Norwegian Pearl could also be called Family Suites since they have a small bunk-bedded room and bath that's perfect for kids.
Non-suite cabins (including mini-suites) have wall-mounted pumps for soap and shampoo, and while it's not ideal in terms of convenience, the rationale for their use is laudable: Just picture the amount of waste generated by 2,000+ plastic bottles each week, and imagine how much less waste is generated by the pumps. The product is actually quite nice ... I am convinced that the shampoo/conditioner combo is a generic version of Herbal Essences.
Suite guests get large containers of upscale designer Frances Denney products, although almost everyone we spoke to who inhabited a suite preferred to go back to the more subtle scents of the L'Occitane en Provence products that had been used in the past.
Twenty-seven cabins, including suites, are fully wheel-chair accessible and ADA compliant.
Pearl's entertainment options span all genres, all age groups, and just about every interest under the sun.
NCL has entered into a partnership with Nintendo to use its Wii interactive gaming system onboard its ships, and with the 20-ft. LED screen in the atrium area, it's a marriage made in gamers' heaven. (The system is also available in both the children's and teen centers.) We loved watching the wired-up kids dancing around in front of the screen, throwing punches (at nothing!), which resulted in grunts, smacking sounds and splats during the boxing match, broadcast in 20-ft. lifelike animation and narrated by a ringmaster. We're old enough so that it was like something out of a Sci-Fi movie to us.
And talk about movies! First run, barely released movies were shown daily, either in-cabin on one of the TV's movie channels, or, again, on the large-screen in the atrium. We were not only impressed, we got to see three flicks that we had missed in the theatre and that were not yet out on DVD.
Other ships might have ice-skating and surf parks, but Pearl has bowling; four family-friendly lanes flanking the funky Bliss Ultra Lounge -- which is filled with beds and pillows, loungers and divans, silky fabrics and low lighting, and which becomes a disco at night. (One young kid we met wanted to spend the night there. "Absolutely not," intoned his mom, again and again.) Bowling costs $5 per person per game, which includes shoe rental, but remember to take socks with you or you'll be denied.
There are, of course, the usual ship-board entertainment options, with production shows in the Stardust Lounge, improv comedy by Chicago's Second City troupe, pianists and singers scattered throughout the ship, audience-participation games put on by the cruise director's staff and some adult-only late-night comedy, magic and game shows. There's a large and lively casino, typical pool games, daily bingo, trivia contests and art auctions.
But then there are the extras that make this cruise special: the murder mystery dinner (only 60 guests are allowed to participate; sign up is on boarding day, but if you're not early enough, you'll end up on a lengthy waiting list), the Ship 'n Males Revue (a take off on Chippendales), wherein crew and members of the cruise director's staff shimmy, shake, and strip down to their briefs to the delight of the ladies waiting for their chance to stuff said briefs with dollar bills, and the individual performers and performances throughout the ship, all at no additional charge.
We've always thought that NCL has an uncanny knack for choosing stellar performers; those appearing on Pearl were certainly no exception. Standouts, to us, were the calypso band that played on the pool deck every day, the talented master of the steel drums who provided soul-soothing sounds at the Great Outdoors every evening, and the trio who played dance music of the 1940's through the 1950's in the atrium, delighting the pre-boomer crowd who took the opportunity to dance, dance and dance.
There's a guest talent show, and our absolute favorite, the crew show, showcasing the talents of the multi-national service staff onboard. When the people who spend their days and nights serving us step into the role of entertainer (and some of them are very talented), or offer a glimpse into their personal lives and culture, they become more than our room steward or favorite bartender. With over 60 nationalities represented on Pearl, they show us what the world can be and should be -- harmonious.
Fitness and Recreation
Pearl is the first of NCL's ships to install a rock climbing wall ... and it's quite impressive. Located at the back of the stack (about 18 stories above the sea), it stands 30 feet tall and 19 feet wide and offers five different climbing routes with levels of difficulty depending on skill level. But that's not all this ship offers in terms of fitness and recreation, not by a long shot.
You might not get an aerobic workout by bowling, but you can do that too (and the oxygenation you'll experience from laughing is worth at least a couple of spinning classes ...). There's also a volleyball/basketball court, mini-golf, two golf driving nets, Ping- Pong, two pools, a jogging track, a full-circuit promenade for walkers, a completely equipped fitness center with the newest of everything, and the full-service South Pacific Spa, which has a thermal suite along with the usual hands-on treatments.
In fact, the thermal suite is one of the best "day of pampering" values onboard, at $15 for a full day's use (less if you buy the package for the whole cruise). It allows the guest to take advantage of the co-ed room with the thalassotherapy pool and heated ceramic loungers, or go gender-specific with an oceanview sauna, eucalyptus steam, individual whirlpool tubs, icy-cold plunge pool and padded chaises. Unfortunately, the purchase of an expensive spa treatment does not confer entrance to this relaxing area before or after the service unless you pay the additional fee. We heard a great deal of grumbling about that. (There are small steam rooms, however, in the rest rooms adjacent to the fitness center, and there is no charge to use those.)
The spa offers the usual array of services and massages, and now includes teeth whitening sessions and acupuncture. Specials onshore days seemed quite reasonable (three mini-treatments for $89, for example), but we always, always go for the Frangipani, a yummy scalp-neck-shoulder massage at the best price -- around $29.
The Body Waves fitness center was open 24 hours during our cruise, but the hours may be cut back. Some of the more expensive suites are located below this area, and apparently, the noise from some of the machinery wreaked havoc on the suite guests' ability to sleep. It's a new gym, so all manner of state-of-the-art equipment is available, free for guests to use. There are classes for Pilates, yoga and spinning that carry a surcharge of $10.
One of the two pools has been designated as "adult only," and it seemed to be monitored. The family pool is just adjacent so you'd think it would be harder to enforce, but in fact it was just the opposite, and worked quite well.
Oh my.
First of all, if we were traveling with toddlers, we'd pick an NCL cruise over any other. Why? Freestyle dining means that the kids don't have to wait for a set dining time. That's one reason. And the Kid's Crew clubs are always terrific, but on Pearl there's an element that makes it even more special. The Aqua Kids Club is located on Deck 12 adjacent to the pool area, and in fact, the outside part extends onto the pool deck. It's surrounded by a glass wall, which means that mom and dad can actually see their kids playing when they are out there, bouncing on the colorful balls or interacting with other children in the same age group.
Kids from six months are allowed in, and get this: They don't have to be potty trained! Parents are given a beeper and paged when a diaper needs changing. (It doesn't work ashore, so you can't leave the ship while your child is in the center.) The center itself features a little movie theatre, a computer center, an outdoor play area, an arts and crafts room, a nursery and sleep room.
Teens have their own space, Metro Center, a "New York subway-themed" club with computers, plasma TV's, cozy seating areas, and (of course) it's adjacent to the well-equipped video arcade.
NCL's new agreement with Nintendo means that both centers now have Nintendo Wii's available for use.
The Garden Cafe has a special kid-sized buffet section, with kid-styled food (hot dogs, fries, chicken fingers) and the room service menu also has great kid's options, like a melt-in-your-mouth grilled cheese sandwich (Yes! We tried it!), and a peanut butter and jelly sandwich.
Not limited to kids, of course, is the fabulous bright yellow corkscrew slide at the pool complex.
Group babysitting is offered during the evenings and on port days for a nominal fee of $5 per hour for the first child, and an additional $3 per hour for each sibling; there is no individual or in-room sitting.
It would be easy to provide a laundry list of the restaurants on Pearl, a Freestyle ship with loads of dining spots, but it wouldn't paint a complete picture. The options run the gamut from a chi-chi and clubby steakhouse to a 24-hour comfort food diner, from an elegant French-inspired bistro to a fabulous Teppanyaki bar. Of course there are standard dining rooms as well, a big one with windows on three sides at the aft called Summer Palace, and a smaller, more intimate one (Indigo) midship. But on Pearl, as on most of NCL's ships, it's all about the choices.
Specialty restaurants have a surcharge, between $10 and $25, and for the more popular ones (Teppanyaki, for example), reservations are requisite.
La Cucina, one of our favorites, is $10 per person. I could have dined solely on the antipasto plate offered there, with olives, sun-dried tomatoes, a couple of thin slices of Parmesan Reggiano, marinated mushrooms and artichoke hearts, thin slices of Parma ham and carpaccio, and rolls and breadsticks with olive oil and balsamic vinegar for dipping. The meat dish (veal) was impressive too, but even better was the perfectly al dente side of linguini carbonara that I chose.
Equally enticing were the spicy rice noodles I had at Lotus Garden (surcharge: $15); the noodles were in a coconut milk broth and the dish reminded me of a Thai Tom Kha soup ... spicy-sweet and coconut-y. My traveling pal had sea bass and a newly made friend, who joined us there for supper, had the Peking duck, both of which looked wonderful. The dessert pancakes were the perfect ending.
Moderno Churrascaria ($20) is a Brazilian-style steakhouse that offers a expansive lineup of skewered meat, including lamb chops, filet mignon, sausage and chicken. There's also the obligatory salad bar featuring international cheeses, dried meats, olives and marinated veggies, alongside the traditional salad ingredients. Sides, including mashed potatoes, fried bananas, and rice and beans, are served with the meat.
Cagney's (surcharge is $25, or more if you opt for items like a bigger steak or surf 'n' surf) is NCL signature steak and chop house. One big point of interest here: When you order the Surf 'n Turf ($15 extra), you don't get one of the rock lobster tails that are typically served on lobster night in the main dining rooms. You get half of a decent-sized crustacean, complete with claws and metal claw-crackers.
This ship has taken the typical Lido Deck "buffet" dining venue to new heights. Gone are the kiosks that are found on the other two Jewel-class ships (Jewel and Pride of Hawaii), and the smaller Pride of America, which look nice in principle, but are chaotic in practice. Pearl's designers brought back linear counters, but NCL doesn't want the Garden Cafe to be called a buffet or cafeteria; it's a restaurant with "action stations." Servers stand behind the counters, where small amounts of freshly-made meals are put out at one time and served. There are stations for salads, sandwiches, fresh pasta, carved meats, soups and vegetarian dishes, Asian food, hot dogs, hamburgers and desserts.
Two items of interest: For some reason NCL has decided to do away with trays. Plates are fairly small, though, so plan on returning to the lines once or twice. Also, for sanitary reasons (and to avoid the sticky, gross mess), there are no self-serve soft ice cream machines on Pearl; hard scooped ice cream, with toppings, is available much of the day, either in cones or in bowls.
Traditionalists can have dinner every night at the same time, in the same place; just let the maitre d' know in advance. Otherwise, the multitude of restaurants allows for some adventurous options. We're pleased that NCL has gone back to the reservation system that allows you to make plans one day in advance; for awhile, you had to book all of the alternate restaurants for the whole cruise as soon as you boarded, and what kind of Freestyle is
? Still, we've heard that if you don't call precisely at 8 a.m. for plans for the following night, you may not get the reservations you desire. We only made reservations once and had no problem just showing up at our restaurant of choice the other times, but we didn't choose to dine at peak periods (between 7 and 8 p.m., for example). We usually ate earlier or later. And speaking of earlier, the surcharge restaurants (with the exception of Teppanyaki and the refined "tasting menu" at Le Bistro) offer a two-for-one special from 5:30 to 7 p.m. If you're concerned about springing for the $25 meal at Cagney's, this is your chance to try it for $12.50...
Breakfast and lunch are served via open-seating at one of the two traditional restaurants, but most take advantage of the Garden Cafe and aft deck Great Outdoors Cafe when the weather is good. There's also a Continental breakfast served in Bar City, with rolls, croissants, juice, coffee, tea, bagels, cream cheese and smoked salmon. The bars aren't open yet, and it's a quiet, pleasant place to have a morning munchie. Suite guests (penthouse and above) can have breakfast and lunch in Cagney's, with a special menu designed just for them, with items like crab cake and eggs Benedict for breakfast and blackened snapper sandwiches for lunch, served in the toney atmosphere of a private club. For those in regular cabins (from insides to mini-suites), room service choices are dreadfully slim, especially for breakfast. You can get rolls, toast or muffins, yogurt, a choice of three dry cereals, milk, coffee, tea or hot chocolate, and something called "orange juice cocktail." We ordered rolls one morning, and we got 'em ... no butter, no jam. Ugh. Happily, the rest of the menu, while horribly limited, does have a couple of standouts: The ramen noodles with green onions is fabulous, loaded with white-meat chicken, and perfect if you've got the sniffles or want something hot and homey. Ditto the grilled cheese sandwich from the kids' menu -- yum. Suite guests get a much more extensive room-service menu, with hot items like eggs and bacon for breakfast, and steak sandwiches or burgers for lunch, and can order meals from the restaurants during serving times.
There's a well-stocked grill out on the pool deck which serves roasted chicken, hamburgers, hot dogs, salads and dessert items during most of the day, and a limited breakfast in the mornings.
Dress Code
Freestyle cruising allows you to dress casually, all the time. There is one optional formal night in which one can dress up if one wishes, but in fact, you can do that on any night of the cruise. You can dress up or dress down, the only caveat being that after 5 p.m., no shorts, tank-tops or jeans are allowed in the dining venues other than the casual Garden Cafe and Blue Lagoon. As NCL's advertising advises, "Wear ... something."
NCL adds $12 per person, per day to onboard accounts, which serves as a "service charge" and not a tip. Passengers are encouraged to "tip" for exceptional service, but we're also assured that the service charge does go to the crew. Most guests tip their room stewards extra; suite guests also tip their butlers and the concierge -- who are not in the "service charge" pool -- and because of Freestyle dining, where you don't have the same waitstaff every night, many guests bring cash to tip their servers if they've done an excellent job. On Pearl, a 15 percent gratuity is also added to bar bills. An 18 percent gratuity is added to spa bills.
The Murder Mystery Dinner on the bright, brassy Norwegian Pearl is just one of the many sea day activities available to its passengers, activities which not only include the usual rituals of poolside lounging, bingo and art auctions, but also some truly innovative and unique options. On that day I could have gone bowling, boxed against a 20-foot opponent (thanks to NCL's partnership with Nintendo, featuring its Wii system on most ships) on the Crystal Atrium's gigantic LED screen, attended both a Martini Tasting clinic and a Margarita Taster, watched an all-male exotic dance show featuring the ship's crew, and settled into a four-poster canopy bed next to the dance floor in the Marrakech-inspired Bliss Ultra Lounge.
Pearl launched in 2006 as the third in the series of Jewel-class vessels (Norwegian Jewel and Norwegian Jade preceded Pearl; Norwegian Gem debuted in fall 2007). This ship, with its spaces, its flow, its dining and lounge options, is one of the most enjoyable large vessels around. The inclusion of a four bowling lanes and the Bliss Ultra Lounge in the space where most NCL ships have their department-store-sized shopping venue is one change, and making the two-story atrium actually functional is another.
Norwegian Pearl is loaded with jewel-toned designs (mauve and teal, turquoise and magenta, purple and blue, all with the occasional splash of fuchsia and orange) and original art (a Dale Chihuly sculpture anchors the atrium, a small Van Gogh reproduction -- the original is being moved from the Dawn later this year -- hangs behind the reception desk), and filled with upscale seating around its two pools and on the upper sun decks (faux wicker chairs and padded chaises, some double loungers with pillows). In addition, it boasts 12 Freestyle restaurants, 11 bars and lounges, the bowling alley, a five-level rock-climbing wall and a contemporary kid's club.
Is Norwegian Pearl perfect? No, but our quibbles are so minor they hardly matter. We hate the tacky plastic flowers that show up in places where there should be real ones or none at all. Somehow, the architects forgot to put a drink station on the pool deck, so to get tea, coffee, water or juice, one has to wander half way through the Garden Cafe in search of a no-surcharge beverage -- irritating, but barely. The myriad of activities, the bright colors, the usability and flow of the ship, the dining and entertainment options, the fabulous itineraries (five-night Western Caribbean, nine-night Southern Caribbean, Alaska in the summer) and especially the happy, friendly, helpful staff make this ship stand out as one of our all-time favorites.
Public Rooms
One of the things that struck us during our cruise is how easy and comfortable the flow is on this ship. There aren't many instances of "you can't get there from here," which is, of course, wonderful. But another thing we really enjoyed is the usability of the Crystal Atrium. NCL chose to make this area two stories tall rather than create an atrium concept with towering empty space. So in this case the Crystal Atrium is comfy and cozy, but it's also still expansive and airy. Surrounded above by two restaurants with rail-side dining, the lower level is filled with chairs, loungers, divans and a cafe/bar, making it seem more like a hotel lobby than a big-ship atrium. And it's actually used, as a meeting space, lounging destination, dance hall, movie theatre, and action spot for those participating in the Nintendo Wii activity du jour. Original art includes the Chihuly sculpture and the small Van Gogh behind the Reception Desk.
NCL moved its typical aft-end shopping venue to the front of the ship, near the Stardust Lounge, and turned the aft space into the Bliss Ultra Lounge and bowling alley, with delightfully whimsical decor (canopied beds as loungers, prompting some to call it the Bliss Bordello). The deck (seven) that holds Bliss, the reception/atrium space, the artwork for the auctions, the Internet center, photo gallery and the Asian restaurants is completely non-smoking, so those who want to avoid the smell of cigarettes can safely traverse from one end to the other without encountering a single whiff.
Just below that deck, on Deck 6, is found Bar City, a unique concept that combines a whiskey and spirits bar, martini bar, wine and champagne bar, and beer pub in one elongated space which then flows into and through the casino (smoking is allowed on most of that deck, and there is an enclosed cigar-smoking room adjacent to Le Bistro).
Decor throughout is bright, tropical, fun. The furnishings in Spinnaker's Lounge look like they were designed by famed Finnish architect
Eero Saarinen
after he watched a couple of episodes of the Jetsons. Teal crushed velvet double-loungers are surrounded by white high-impact plastic bucket chairs ... with holes where one expects a seat. And guess what? They are comfortable!
Forward of the pool are a couple of meeting rooms, the spa and exercise facility, a small chapel, a card room and an attractive library that is open, alas, too few hours to be truly effective for book and game checkout.
The Stardust Theatre comprises three decks with comfy seating and good site-lines from almost everywhere. Located adjacent to its entrance on Deck 7 is the newly redesigned Trade Routes Boutique complex, a series of shops broken into smaller venues featuring duty-free goods and costume jewelry in one, logo items in another, clothing and high-end jewelry in a third, and so on.
Fellow Passengers
There is something for everyone to enjoy on Norwegian Pearl, and as a result, ages are all over the board. It's designed for families, so of course there are plenty of kids; it has a super teen center so that age group is well-represented too. But the range of cabin types, dining and entertainment options have appeal for seniors, boomers, Gen X's and Y's, families, singles, honeymooners, grandparents and grandkids, and everything in between. We saw them all on our nine-night Southern Caribbean cruise over spring break; we understand that the five-night cruises just before and just after ours had many more college students and youngsters aboard.
Also, the euro and the British pound are very favorable against the dollar at this time, so there were many Europeans and Brits on our nine-night cruise. Many of them take the opportunity to do a back-to-back, incorporating both the five-night and the nine-night for a full two weeks of cruising heaven.
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subset: commoncrawl


text:
- Product nameAnti-AKT1 antibodySee all AKT1 primary antibodies ...
- DescriptionRabbit polyclonal to AKT1
- SpecificityThere will be cross reactivity with AKT2 and AKT3.
- Tested applicationsWB, IHC-P, ELISA more details
- Species reactivityReacts with: Mouse, Human
- Immunogen
A synthesized non phosphopeptide derived from human AKT1 around the phosphorylation site of Serine 473.
- Positive control
- WB: Extracts from HeLa cells IHC-P: Breast carcinoma tissue
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4 - Concentration information loading...
- PurityImmunogen affinity purified
- Purification notesThe antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
- Clonality Polyclonal
- IsotypeIgG
Research Areas
Our Abpromise guarantee covers the use of ab47610 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Notes |
WB | WB: 1/100 - 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa). |
IHC-P | IHC-P: Use at an assay dependent dilution. |
- FunctionPlays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation (By similarity). General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. The activated form can suppress FoxO gene transcription and promote cell cycle progression. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.
- Tissue specificityExpressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
- Involvement in diseaseDefects in AKT1 are a cause of susceptibility to breast cancer (BC) [MIM:114480]. A common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type. Breast cancer is etiologically and genetically heterogeneous. Important genetic factors have been indicated by familial occurrence and bilateral involvement. Mutations at more than one locus can be involved in different families or even in the same case.
Defects in AKT1 are associated with colorectal cancer (CRC) [MIM:114500].
Defects in AKT1 are associated with susceptibility to ovarian cancer [MIM:604370]; also called susceptibility to familial breast-ovarian cancer type 1 (BROVCA1). - Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 PH domain.
Contains 1 protein kinase domain. - DomainBinding of the PH domain to the phosphatidylinositol 3-kinase alpha (PI(3)K) results in its targeting to the plasma membrane. The PH domain mediates interaction with TNK2 and Tyr-176 is also essential for this interaction.
The AGC-kinase C-terminal mediates interaction with THEM4. - Post-translational
modificationsPhosphorylation on Thr-308, Ser-473 and Tyr-474 is required for full activity. Activated TNK2 phosphorylates it on Tyr-176 resulting in its binding to the anionic plasma membrane phospholipid PA. This phosphorylated form localizes to the cell membrane, where it is targeted by PDPK1 and PDPK2 for further phosphorylations on Thr-308 and Ser-473 leading to its activation. Ser-473 phosphorylation by mTORC2 favors Thr-308 phosphorylation by PDPK1. Ser-473 phosphorylation is enhanced by interaction with AGAP2 isoform 2 (PIKE-A). Ser-473 phosphorylation is enhanced in focal cortical dysplasias with Taylor-type balloon cells.
Ubiquitinated; undergoes both 'Lys-48'- and 'Lys-63'-linked polyubiquitination. TRAF6-induced 'Lys-63'-linked AKT1 ubiquitination is critical for phosphorylation and activation. When ubiquitinated, it translocates to the plasma membrane, where it becomes phosphorylated. When fully phosphorylated and translocated into the nucleus, undergoes 'Lys-48'-polyubiquitination catalyzed by TTC3, leading to its degradation by the proteasome. - Cellular localizationCytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated form translocates to the nucleus.
Target information above from: UniProt accession P31749 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) . -
Database links
- Entrez Gene: 207 Human
- Entrez Gene: 11651 Mouse
- Omim: 164730 Human
- SwissProt: P31749 Human
- SwissProt: P31750 Mouse
- Unigene: 525622 Human
- Unigene: 6645 Mouse
Alternative names
- AKT 1 antibody
- AKT antibody
- AKT1 antibody
- AKT1_HUMAN antibody
- C AKT antibody
- MGC9965 antibody
- MGC99656 antibody
- Oncogene AKT1 antibody
- PKB antibody
- PKB-ALPHA antibody
- PRKBA antibody
- Protein Kinase B Alpha antibody
- Protein kinase B antibody
- Proto-oncogene c-Akt antibody
- RAC Alpha antibody
- RAC antibody
- RAC PK Alpha antibody
- RAC Serine/Threonine Protein Kinase antibody
- RAC-alpha serine/threonine-protein kinase antibody
- RAC-PK-alpha antibody
- vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
see all
Anti-AKT1 antibody images
All lanes : Anti-AKT1 antibody (ab47610) at 1/100 dilution
Lane 1 : Extracts from Hela cells. No heat shock and no peptide.
Lane 2 : Extracts from Hela cells. No heat shock. Preincubated with synthesized peptide. with synthesized peptide at 1 µg/ml
Lysates/proteins at 30 µg per lane.
Predicted band size : 56 kDa
Observed band size : 56 kDa -
Immunohistochemical analysis of paraffin embedded breast carcinoma, using ab47610 at a 1/50 dilution.
References for Anti-AKT1 antibody (ab47610)
ab47610 has not yet been referenced specifically in any publications.


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a softer world |
"We gladly feast on those who would subdue us."
Joey and I started making news posts in early 2008, but we didn't have archives for them until now! So I'm going to repost here some of my old links here: Society in Decline:Intrastate Commerce - yet more evidence that the USA (in general) has done a better job holding on to great midcentury signage. Year 2008 in Photographs - the Boston Globe's The Big Picture has a three-part best of series, this is part one. Foodpairing - teaches you how to combine your foods in new ways, AND it has suggestions for substitutions. The Selby - beautiful photographs of beautiful people in their beautiful homes. Like the best decor magazine you've ever seen without all the ads for flooring. Früli - the fruitiest beer I've ever drunk. Free Rice - show off your vocabulary AND feed people. Corey Arnold - the coldest, loveliest photos you'll ever see. Ali Bosworth - a photographer who lived in Victoria when I was there. Maybe the opposite of the above shots, Bosworth's tend to be warm and drowsy.
I have a new book! It is called THE SUMMER IS ENDED AND WE ARE NOT YET SAVED. Here is the synopsis:
Martin is going to Bible Camp for the summer. He's going to learn archery and swimming, and he's going to make new friends. He's pretty excited, but that's probably because nobody told him that this is a horror novel!
And this is what Booklist said in their review:
Lean and mean and hugely entertaining, with no high-falutin literary pretensesnote to fans of slasher flicks: yes, the villain is exactly who you think it isbut with a genuinely shocking conclusion, the book should be a big hit with old-school horror fans. - Booklist
I am very excited that this book is coming out! You can buy it here.


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Join the Education Law Society for a movie screening of:
The Cartel
Join us for a screening of The Cartel, a 2009 documentary film exploring the failures of public education in the United States through the lens of New Jersey, which has the highest level of per-student education spending in the country. Students interested in education law will come away with a deeper understanding of the challenges faced by the American public education system.
Date Wednesday, January 16, 2013
Time 6 - 8 p.m.Location School of Law | Room LL-03 | Lower LevelMore Information Courtney email@example.com


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Latest News
Pope asks Vatican Curia for professionalism, service and holiness
December 21, 2013. "Gossip is harmful to people, harmful to our work and our surroundings", said Pope Francis in his Christmas address to the Vatican Curia. He warned that "when professionalism is lacking, there is a slow drift downwards towards mediocrity". "And when the attitude is no longer one of service to the particular Churches and their bishops, the structure of the Curia turns into a ponderous, bureaucratic customshouse, constantly inspecting and questioning, hindering the working of the Holy Spirit and the growth of God's people", he added.
Papal Appointments
December 19, 2013. Pope Francis accepted the resignation of Msgr. Juan Horacio Suárez, and named Msgr. Gabriel Bernardo Barba as the new bishop of Gregorio de Laferrere (Argentina). He also appointed Msgr. Jean-Marc Aveline as the new auxiliary bishop of the Archdiocese of Marseille (France). Lastly, the Pope confirmed Card. Angelo Amato as the prefect for the Congregation for the Causes of Saints.
Pope's Schedule
December 19, 2013. Pope Francis will welcome the Prime Minister of St. Vincent and the Grenadines at 10:30AM. Half an hour later he will meet with Msgr. Adriano Bernardini, the Apostolic Nuncio to Italy and San Marino. At 11:30AM, the Pope will meet with Msgr. Bernardito Auza, the Apostolic Nuncio to Haiti. And lastly, at 12:30PM, he will meet with Fr. Edmund Power, Abbot of St. Paul Outside the Walls.
Pope will visit Argentina in 2016
December 18, 2013. Pope Francis announced he will be traveling to Argentina in 2016 for the National Eucharistic Conference that will take place in the northern provice of Tucuman. He made the announcement as he met privately with members of his beloved San Lorenzo de Almagro soccer team. They traveled to the Vatican to hand him the championship trophy they won on Sunday.
Papal Appointments
December 18, 2013. Pope Francis appointed Msgr. Robert Peter Deeley as the new bishop of the Dioecese of Portald (USA). The Pope also named Msgr. Luigi Bonazzi as the new Apostolic Nuncio to Canada, his prevoius post was in the Baltic States.
Pope Francis advances the beatification process for nun, priest and layman
December 17, 2013. Pope Francis issued a decree to certify a miracle attributed to the intercession of American nun Maria Teresa Demjanovich. He also recognized the heroic virtues of Emanuele Herranz Establés, a Spanish priest and founder of the Congregation "Esclavas de la Virgen Dolorosa." Lastly, he recognized the heroic virtues of Giorgio Ciesielski, a Polish layman and family man.
December 17, 2013. Pope Francis has appointed American Rev. John F. Doerfler, as the new Bishop of Marquette (USA).
Pope Francis turns 77
December 17, 2013. Tuesday marks the Pope's birthday. His day started off with his daily morning Mass in Santa Marta. Among those in attendance were employees who upkeep the Vatican's Casa Santa Marta residence, where he lives. Four homeless people also attended the Mass and got to congratulate the Pope.
December 16, 2013
Pope Francis has appointed Canadian Cardinal Marc Ouellet, 69, as the prefect for the Congregation of Bishops.
Papal Appointments
December 14, 2013. Pope Francis accepted the resignation of Msgr. Manuel Gerardo Donoso Donoso, and named René Osvaldo Rebolledo Salinas as the new archbishop of La Serena (Chile). The Pope also appointed Msgrs. Stanisław Salatersky and Jan Piotrowsky as auxiliary bishop of the Dioecese of Tarnów (Poland). Lastly, he also named Fr. Michele Petruzzeli as the Abbot Ordinary for the Territorial Abbey of La Trinità della Cava (Italy).
Papal Appointments
December 10, 2013. Pope Francis appointed Msgr. Jesús Fernández González as the titular bishop of Rotdon, and auxiliary bishop for the archdiocese of Santiago de Compostela (Spain). The Pope also appointed Fr. Urban Federer as the Abbot Ordinary of the Territorial Abbey of Maria Einsiedeln (Switzerland).
Council of Europe approves Vatican's Progress Report on Anti-Money Laundering and Financing of Terrorism
December 9, 2013. MONEYVAL, the "Committee of Experts on the Evaluation of Anti-Money Laundering Measures and the Financing of Terrorism" has approved today the Progress Report of the Holy See/ Vatican City State.
Pope issues decree for Causes of Saints
December 9, 2013. Following a meeting with the prefect for the Congregation for the Causes of Saints, Pope Francis declared an Italian priest killed in Myanmar (Burma) a martyr. He also confirmed a miracle attributed to a late Italian nun, and he recognized the heroic virtues of 10 other Servants of God.
Pope's Schedule
December 9, 2013. On Monday morning, Pope Francis welcomed Denis Sassou-Nguesso, president for the Republic of the Congo at 10:30AM. Immediately after, he met with Card. Angelo Amato, the prefect for the Congregation for the Causes of Saints. At 11:45, the Pope welcomed Card. Elio Sgreccia, president emeritus of the Pontifical Academy for Life. He was followed by Msgr. Giambattista Diquattro, Apostilic Nuncio to Boliva.
Papal Appointments
December 9, 2013. Pope Francis appointed Ghanian Card. Peter Turkson as the Vatican's special envoy to the Official Ceremony in honor of late South African President Nelson Mandela. The ceremony for the beloved leader will take place on Tuesday, December 10, in Johannesburg. Over 60 other heads of state and government are expected to attend.
Papal Appointments
December 6, 2013. Pope Francis accepted the resignation of Msgr. Alessando Pagani, and named Msgr. Monfort Stima as the Bishop of Mangochi (Malawi). The Pope also appointed Rutilo Felipe Pozos Lorenzini and Tomás López Durán as auxiliary bishops for the Archdiocese of Puebla (Mexico).
Pope's Schedule
December 6, 2013. The Pope's Friday schedule began at 9AM with the second Advent Sermon at the Redemptoris Mater Chapel. At 9:45, he met with Card. Antonio Cañizares Llovera, prefect for the Congregation for Divine Worship, followed by Card. Karl Josef Becker. At 10:30, the Pope welcomed António Guterres, United Nations High Commissioner for Refugees. At 11, he met with Msgr. Joseph Spiteri, Apostlic Nuncio to Ivory Coast, and then with Msgr. Edgar Peña Parra, Apostolic Nuncio to Pakistan. His morning schedule ended with an audience with the International Theological Commission at 12:10PM.
Pope creates new commission to help sex abuse victims
December 5, 2013. Boston Cardinal Sean O'Malley announced that Pope Francis has approved the creation of a new commission to help prevent the sexual abuse of children, as well as to provide "help and support" for victims. The commission was an idea generated by the Council of Cardinals and approved by the Pope.
Vatican Secretary of State greets Council of Cardinals
December 4, 2013. During their Tuesday afternoon session, the Vatican said the Council of Cardinals met briefly with Msgr. Pietro Patrolin to congratulate him on his new post as Secretary of State. The G8 continued their work into Wednesday, analyzing each of the Roman Curia's departments. Pope Francis was not in the morning session, since he had the General Audience.
Pope talks about resurrection during General Audience
December 4, 2013. The Pope continued his series on the Creed during Wednesday's General Audience. He spoke about the resurrection of Jesus Christ and its relationship to Catholics today. The General Audience took place in St. Peter's Square, instead of the Paul VI Hall, as normal for this time of year.
Papal Appointments
December 3, 2013. Pope Francis accepted the resignation of Msgr. Antonio Bayter Abud, and named Fr. Joselito Carreño Quiñonez to take his place as Apostolic Vicar of Inírida (Colombia). He also named Carlos Alberto Correa Martinez as Apostolic Vicar to Guapi (Colombia); and Msgr. Jorge Vásquez and Fr. Carlos Alberto Novoa de Agustini as auxiliaries in Lomas de Zamora (Argentina).
Pope's Schedule
December 2, 2013. Today the Pope will meet at 10:30 a.m. with Israeli Prime Minister Benjamin Netanyahu. Then at 11:15, with Cardinal Julio Terrazas Sandoval, the archbishop emeritus of Santa Cruz de la Sierra (Bolivia). At 11:30, he welcomes the Bishops' Conference of the Netherlands for an "ad limina" visit.
Papal Appointments
November 29, 2013. José Luis Gerardo Ponce de León, I.M.C., is the new bishop of Manzini (Swaziland). The Pope also named him as Apostolic Administrator for the diocese, ad nutum Sanctae Sedis. In Belarus, Aleh Butkevich is the new bishop of Vitebsk; Yury Kasabutski is the new auxiliary bishop of Minsk-Mohilev; Iosif Staneuski is the new auxiliary bishop of Grodno.
Pope Francis meets with superiors general of religious congregations
November 29, 2013. Pope Francis met with the members of the Union of Superiors General at the Paul VI Hall on Friday morning. The union brings together the leaders of men's religious congregations worldwide.
Pope's Agenda
November 28, 2013. Pope Francis held audiences with:
-Gerhard Ludwig Müller, prefect for the Congregation for the Doctrine of the Faith.
-Diego Causero, Apostolic Nuncio to Switzerland and Liechtenstein.
-Luigi Pezzuto, Apostolic Nuncio to Bosnia and Herzegovina, and Montenegro.
-Brother Alois, Prior of Taizé
-Participants of the Plenary for the Pontifical Council for Inter-religious Dialogue.
Papal Appointments
November 28, 2013. Pope Francis named Msgr. Alfred Xuareb as a member of the Pontifical Commission for the IOR, or Vatican Bank, as well as the temporary commission tasked with analyzing the economic and administrative structure of the Holy See.
Pope's Mass: Faith is not a private act
November 28, 2013. During Mass at Casa Santa Marta, Pope Francis said there are "mundane powers" that want turn religion into something private. He added that perscuted Christians today are a living example of what's to come before Jesus' final glory.
Pope to Catholics: Spread the Faith
November 26, 2013. Evangelii Gaudium: The Pope's first apostolic exhortation is published! Divided in five chapters, the document includes 288 points, where he asks Christians to transmit the joy that comes through faith.
Pope meets with Heads of State
November 25, 2013 This afternoon, Pope Francis will meet with Russian president Vladimir Putin at the Vatican's Apostolic Palace.
Paraguay's president, Horacio Cartes meets Pope Francis at the Vatican.
Pope explains the meaning of Catholic rites and celebrations
November 22, 2013. During the morning Mass at Casa Santa Marta, Pope Francis explained that the true meaning behind the liturgical ceremonies and rites is to praise God. He spoke about the need for Catholics to purify themselves constantly so that God can live inside them.
Pope greets Argentina and Italy rugby teams
November 22, 2013. Pope Francis welcomed the players from the Italian and Argentine rugby teams, ahead of their match in Rome on November 24. He spoke about the importance of being a team player in life, and always running towards the goal line.
Pope's Nominations for Thursday
November 21, 2013.
Bogor, Indonesia: Fr. Paskalis Bruno Syukur, O.F.M., was appointed Bishop.
Blantyre, Malawi: Msgr. Thomas Luke Msusa has been appointed Archbishop.
Apostolic Vicar, San Miguel de Sucumbios, Ecuador: Msgr. Celmo Lazzari.
Pope meets with Patriarchs and Major Archbishops of Eastern Churches
November 21, 2013. Pope Francis welcomed the leaders of the Eastern Churches in full communion with Rome at the Vatican's Apostolic Palace. During his remarks, he expressed his solidarity with their Churches, in particular those in the Middle East.
#Art & Culture
The 'normal' side of Cleopatra on display at Egyptian exhibit in Rome
She was the world's first celebrity, perhaps the most famous queen of all time. Just her name, Cleopatra, evokes many stories and legends: the heavy eye make up; milk baths; her affair with Julius Caesar.
Pope Francis meets with Italian prison chaplains: No cell can isolate from God
Pope Francis welcomed the members of the National Convention of Italian Prison Chaplains.
Vatican suspends German bishop accused of misusing Church funds on official home
The Vatican announced that it was temporarily suspending the German bishop accused of misusing Church funds to renovate his official home in the Diocese of Limburg.
All News
What the Pope can expect during his flight to Brazil
Traveling to Brazil, for World Youth Day, marks the Pope's first international trip. On Monday morning, after greeting religious leaders and Italian politicians, the Pope boarded a plane and took off to Rio de Janeiro.
Cardinal Godfried Danneels turns 80. Number of Cardinal electors drops to 112
Belgian Cardinal, Godfried Danneels, will turn 80 years old on June 4th. At that age, the archbishop emeritus of Brussels will lose the right to vote in an eventual conclave.
Rome on instagram
Rome on instagram
FAO alert: 868 million people in chronic hunger
The Food and Agriculture Organization of the United Nations reports that 868 million people, 12.5 percent of world's population, suffers from hunger.
Pope calls for unity, asks all Catholics to pray for the Church in China
May 22, 2013. (Romereports.com) During this weeks catechesis, the Pope talked about how the Holy Spirit helps Catholics in their every day lives. He improvised a few words, calling on Catholics to build unity among them. He also asked faithful to pray for China and to reflect on their personal lives.
Pope meets with players of 'Juventus,' Italy's Soccer Champions
May 22, 2013. (Romereports.com) Its no secret thatthe Pope is a big soccer fan. Since the Juventus de Turin team won the Italian championship, the Pope met with the coaching staff and team captains. It was quite obvious that the Pope follows the latest sports news, but especially those involving his favorite team of San Lorenzo de Almagro.
Pope Francis sends letter to young prisoners in California
May 20, 2013. (Romereports.com) These images of Pope Francis washing the feet of young prisoners on Holy Thursday, traveled a lot further than Romes juvenile detention center. From afar, young inmates, who face life in prison, in the County of Los Angeles, were directly touched by the Popes actions. Through the Jesuit Restorative Justice Initiative, some of those prisoners, sent letters to Pope Francis thanking him for sharing that day with prisoners, and also asking for prayers.
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December 24, 2013 - Christmas Eve Mass
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Thursday Dec 26th Angelus@ 12.00
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Sunday Dec. 29th Angelus @ 12.00
February 17, 2014 - Council of Cardinals Meeting
Rome February 17, 18, 19.
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# World
Robert Schuman, a European politician that could soon be declared a saint
December 22, 2013. It will soon be 50 years since the Luxembourg politician, known as one of the "European fou ...
# Pope
Pope Francis sends out his Christmas cards
December 21, 2013. It shows a sheep, which is one of the images, Pope Francis often uses in his homilies.
Pope Francis is the newest draw at Rome's Wax Museum
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Going back to the 'Catholic Church' for Christmas
It's website www.comehomeforchristmas.co.uk encourages Catholics who never or r ...
Pope Francis will greet children hospitalized at the Vatican's Bambino Gesù
December 21, 2013. The visit will take place Saturday ...
Pope's Mass: To understand God's Mystery, embrace silence, reflection
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December 20, 2013. Benedict XVI and Pope Francis easily take the top spot.
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This is the bible study I did last summer- I recommend it. Esther Leader's Kit: It's Tough Being a Woman
Nicholas Christakis, a physician and social scientist at Harvard, found when examining data from a long-term study of the residents of Framingham, Mass., health habits can be as contagious as a cold virus. By his calculation, a Framingham individual's chances of becoming obese shot up by 57 percent if a friend became obese. -People Who Forget To Die
Through Liz's Example , I really saw what an influence a homemaker can have. How it's not about drudgery or thankless martyrdom as you swoon from one unkempt room to another, it's about setting the whole tone for your family. It's not about being the family servant, it's about serving your family by creating a place of peace, a place of warmth, a place of safety through your nurturing efforts. It's not mindless labor. It's an artform. And once I caught on that I had a choice – I could do everything halfway and whine about the fact that I had to feed myself everyday, or I could sack up and do it right – I set about my artistic training. -Reese Dixon
"Life is not about waiting for the storms to pass … it's about learning how to dance in the rain."


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The La Quinta Inn Midland is the place to stay for clean comfortable rooms and great service. Enjoy our free Bright Side Breakfast each morning of your stay, a sparkling swimming pool for your enjoyment, and contracted workout facilities.
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"Wall St. La Q in Midland, TX"
Reviewed Dec 9, 2013
A La Quinta traveler |
I have stayed at this hotel many times for the last 10 years and have always found the staff to be outstanding and the hotel make every effort to meet my needs as I travel with medical / refrtigeration needs and with pets. I would like to see a grassy pet area, but that is a minor issue overall. It is an older facility, but they make me feel welcome. I like parking at my door, as well.
...see more
"Needs to be remodeled"
Reviewed Nov 25, 2013
Michael O | Riverside, California
This site needs to be closed down and remodeled... also, this is more of a motel, than a hotel as all of the room doors are on the outside. The pool is eternally closed (based on other commenters), the tub is disgusting, the cleaning crew definitely needs to learn how to vacuum... The heater and A/C in my room were barely sufficient. Now onto a nice thing, the hotel does have TV in HD, with a nice guide, and a respectable number of channels (to the commenters who complained about this, most hotels that I have stayed at have had around 20-30 at most, and then in SD) The hotel WiFi sucks, its there, but the internet connection is not enough to support the load. I usually just ended up turning on the hotspot function on my 4G phone, and got better service. Regarding the train tracks that others posted about, I think that unless you are a very light sleeper, if you are on the back half of the property (where I was) you won't notice it too bad.
...see more
"Dirty and charged 3x"
Reviewed Oct 28, 2013
krystal h | Lubbock, Texas
Room smelled bad. Shower was very dirty. Just checked credit card and I was charged THREE times for my room! Sure wish I had read the reviews before making reservations. Thought since it was a La Quinta it would be decent. We reserved 12 rooms and everyone had complaints. Do NOT stay here!
...see more
"Good Enough"
Reviewed Oct 13, 2013
westexmom | CC, TX
My stay was on 10/07/13. Check-in was quick and easy and staff were considerate. Room did need some vacuuming. I am aware of the high priced hotel rates, so I got this room for a reasonable rate. Because I had an early departure flight the next morning, it was convenient that the hotel is not too far from the airport.
...see more
"Upon Closer Inspection"
Reviewed Oct 8, 2013
Gideon_Krasmanic | San Antonio, TX
I stayed here on the night of 10/7/13 in Rm. 151. The room was booked for me for a business trip. I noticed the bad reviews AFTER the room was booked and dreaded what I'd find. The hotel exterior is pretty old, but that's okay. The lobby looked fairly nice, check in was quick, and the front desk staff were friendly and efficient. My first look into the room I thought everything looked okay, and was relieved, based upon the reviews. As I was getting settled in the room, I noticed lots of un-vacuumed "stuff" - a few steps inside the front door, under the sink vanity, under the business desk, and between the bed and the nightstand (see pic). The bed and pillows were comfortable, and the sheets looked a little wrinkled (see below), but didn't think much of it at the time. No trouble with parking, but the hotel is off an odd frontage road. If you're passing from East to West, its probably easy to get in and out of the property, but not West to East, or about the town of Midland itself. Breakfast wasn't that great - individually packaged pastries, some fruit, hardboiled eggs, juice, (stale) biscuits and gravy, cereal, and make-your-own waffles. After breakfast, anticipating another night's stay, I called the front desk and asked them to have housekeeping vacuum thoroughly. I also placed the hotel card on the pillows, indicating that I want my linens changed, which they don't do unless requested to conserve water and energy. My client cancelled my expected 2nd night to send me elsewhere, and I had to return to pack and check out just before the checkout deadline. Housekeeping had come by, but the requested vacuuming had not been done. Also, the bed was made, but the sheets were not changed as I requested. How do I know? Upon a hunch (the wrinkled sheets I mentioned), I placed a very discreet dot on the sheets in a specific place in pencil (can be washed out). Checking the sheets - that small, faint dot was still there, telling me the sheets were not changed! So, if you're in this room after me, you probably don't have clean sheets, and I'm not confident I had clean sheets myself! Internet worked well, and the room was spacious. A/C didn't cool well, and would only work on the Auto setting. Flat screen TVs are in the room, and I liked that the TV had satellite vs. cable - I like being able to see a program schedule at a glance and select from there, however, there weren't many channels - less than 40. Water in the shower was hot and had good pressure, but the shower head was set very low - like for someone 5' tall. I'll try somewhere else next time I'm in Midland.
...see more
Traveler reviews are the opinions of individuals travelers and not of TripAdvisor LLC or its partners. © TripAdvisor LLC
Area Attractions & Landmarks
Commemorative Air Force Museum , 9 mi.
Permian Basin Petroleum Museum, 3 mi.
Museum of the Southwest, 3 mi.
Haley Planetarium, 4 mi.
The Petroluem Museum, 5 mi.
Childhood Home of George Bush, 5 mi.
Stream of the Desert, 5 mi.
Area Companies & Businesses
Nearby Sports & Recreation
Water Wonderland, 9 mi.
Grande Communications Stadium, 5 mi.
Scharbauer Sports Complex, 5 mi.
Midland RockHounds (AA Baseball), 5 mi.
Nearby Restaurants
Denny's, 1 mi.
Clear Springs Cafe, 4.5 mi.
Luigi's, 5 mi.
Wall Street Bar & Grill, 5 mi.
Entertainment & Shopping
Midland Park Mall, 5 mi.
Midland, TX
Local Time: 2:44 PM (Central)
Local Temperature: 54.5°F
5-day Forecast


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QCAD - 2D CAD System.
Click here for a documentation of the DokuWiki formatting syntax that can be used in reports
Please search for existing tasks (also closed ones) before opening a new task.
Please make sure that you are using the latest Version of QCAD before posting a bug (menu Help - Check for Updates)
FS#545 - russian codepage error in Layer list
Opened by Dmitry Mikhailov (scaramush) - Thursday, 12 April 2012, 15:39 GMT+1
1. Creating new file
my guess, that the problem is that whole file is encoded as ANSI: $DWGCODEPAGE 3 ASCII 9
but layer names are coded as UTF-8. |
There have been some improvements in that area (codepage support) in QCAD 3.1.4.
Dmitry, could you check if that problem still persists?


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Did you know we have a Writer of the Month contest? Come join it. Entries for WOTM #32: Change are up for voting until December 17th. Casual | Advanced Originally Posted by Sophistikit I don't know why, but this fucking killed me. Maybe it's your utter determination to be an asshole, but wow, I lol'd. Originally Posted by Turtlicious And now I can't stop laughing, Thanks Jorick. <3 Originally Posted by Darkdrago666 You loveable asshole, you. You are blunt, and to the point. Originally Posted by Sophistikit If I had feels, they'd be all yours. :'D Originally Posted by Myyt Jorick: This guy is an evil genius. In the dry, in your face trufax sorta way. If you ever want the blunt truth, this is the guy to ask, which makes him amazing. Originally Posted by Esper Jorick is one of those people you shouldn't take seriously. He is rude for the sake of being rude much of the time. Outside of Spam that is not who he is, but here in Forum that is how he carries himself. Why do I respect that? He doesn't give an apology for being himself or making ridiculous claims to deflect when people call him on it. Jorick is Jorick, a charismatic ass to the end. Originally Posted by Elendra Ladies, contain your orgasms for Jorick I had dibs first. Originally Posted by Rilla Put it this way. If me and Jorick meet docile or non-docile lifeforms... they'll bow. Without a fight. Why? Because it's me and Jorick. We'll use our combined charisma, wit, and generally dickish attitudes, to put them in their unwelcome places. Vote Rilla/Jorick - Space Emperors... To Infinity... and Beyond. Originally Posted by overwatch When Jorick says something, It's like adding a 100,000 ton weight onto a side of a scale. Originally Posted by Kill Bones Jorick is like a monster truck shaped like a t-rex He is elegantly designed, menacing, loud, a bunch of people love him for reasons I don't understand, and he makes no fucking sense when described by similes Originally Posted by Walker of Darkness You're an egotistical, sociopathic, insufferable jackass, but you stick to your convictions and in general show others respect until they prove to be nothing more than bumbling idiots. You've also shown a kinder side from time to time, but very rarely. Other than your blown out of proportion ego, I have no issues with you. Originally Posted by ★LunaLight★ Jorick, I find you to be really witty and fun. I'm also jealous of your writing ability. I get mad at you when you do stupid things that get you banned, but at the same time I don't think it is my place to tell you those things since we aren't good friends yet. You seem like the kind of person I would consider dating. Originally Posted by Hank Jorick is a monster. The way he perfectly knows how to emulate this depravity of a subculture with cold, unerring accuracy is just inhuman. Ted Bundy raped and killed women. Jorick's worse. Originally Posted by PrimezTime I imagine Jorick as Khal Drago. His victim would either suffer, take it, and cry about it or learn to please him and become his Khaleesi. Originally Posted by SmexySpiral I think Jorick's the only person who can make giant posts and I'll still read them anyway.
Wow, this was actually pretty well put. <3
Originally Posted by Scribz Wow, this was actually pretty well put. <3 <3
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Originally Posted by Sophistikit </3 wut
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- 75 GPD Reverse Osmosis Membrane - Dow Filmtec
Membrane Flush Kit
$10.99 As low as: $10.49 -
Standard RO Membrane Housing
$8.99 As low as: $8.49 -
Reverse Osmosis Flow Restrictor
Starting at: $4.99
Reverse Osmosis Membrane Housing Clips
Starting at: $1.19
Specs Says it all. great membrane. all i buy By BuckeyeFrags26 on 12/12/13
BuckeyeFrags26 would recommend this product to a friendThis specific membrane in general is the only type and manufacture that I use in my RODI system. I just now had to replace mine after 1 year of use. And I have to 32 gallon water wells , one for mixing my saltwater one for my r.o. H²O. And I currently have a 125gal reef Display and a 55gal frag tank so I use my r.o. system on a weekly basis. So I can't say enough good things about this product and manufacture. -
Long lasting By Nish on 10/21/13
Nish would recommend this product to a friendVery good product, long lasting. Performing as expected. -
Good Product By Eric on 7/5/13
Eric would recommend this product to a friendKnocks tds down to 8 ppm. Works well. Will buy another at some point. -
Only the best! By Andy on 5/15/13
Andy would recommend this product to a friendI have always used this membrane from day one. Best on the market. -
Easy thing to go to150 gallon I every done By BG on 5/4/13
BG would recommend this product to a friendOriginal had a 50 Gallon per day unit RO units, Purchased 2 75 gallon RO and various pieces to make conversation. When like a dream ( not nightmare) and now getting all RO water I can use in one day. Have three 55 drums setup for Top of Unit and salt making to support my 135 and 92 gallon reef and Fish only tanks. Wish I did this conversation years ago. Water bill and time I save is great. BRS sells upgrade setup for 75 gallon RO and it is really worth the cost to lower you water usage. Thanks BRS for video that directed me to doing conversation. -
Excellent Product By STEVEN on 4/3/13
STEVEN would recommend this product to a friendI purchased this product to upgrade from a 50 gpd. I am very happy with the performance of this ro membrane and would purchase again. -
75 GPD Reverse Osmosis Membrane By Big Dog on 4/1/13
Big Dog would recommend this product to a friendThis 75 GPD Reverse Osmosis Membrane is the best one you can buy in my opinion. I have used this brand in the past and each one has lasted me over 3 years each. It's worth the money. -
High Quality By Chris on 3/24/13
Chris would recommend this product to a friendHigher quality than my old membrane. Fit perfect with my RO unit from another company. -
Outstanding By Dave on 3/9/13
Dave would recommend this product to a friendRetrofited a drinking water system witth this 75 GPD membrane. Worked great. Now I have enough water for the house and thee tank! -
Never will buy any other brand again By Mattyp on 1/11/13
Mattyp would recommend this product to a friendthis membrane filters so much better then the other brand that came in my RO unit from another brand it removes a lot more dts so it makes the di stage last longer Buy this your tank will appreciate it!!!! -
If your gonna make your own water this filter is top of the line. By Rob Coberg on 12/9/12
Rob Coberg would recommend this product to a friendI bought one for my ro /di system and it gets me the 000 tds I need to keep my reefs happy & healthy. -
HIGH QUALITY By MAREK on 12/4/12
MAREK would recommend this product to a friendI'm using only Filmtec membrane and I think it's the best.
Reverse Osmosis Filters Demo
In this episode of BRS TV we are going to go over ...
More15113 Views -
How to Know When to Change your RO/DI Filters
In today's episode we are going to go over when t ...
More41267 Views
Ask a Question About '75 GPD Reverse Osmosis Membrane - Dow Filmtec'
Previously Asked Questions
by Linh on October 25, 2013, @3:56 PM
I have purchased a 75g 5stage plus rodi 6mths ago and wanted to know how long should the membrane and di resin last. From the first time I used it my tds coming in to the di chamber starts around 120 for afew minutes then gets down to 10. Comes out to 0 going out of the di chamber. Does this sound about right or do I need to change the membrane. I've change the sediment filter also. Thanks.
Bulk Reef Supply Hi Linh,
That sounds pretty typical. It is higher at first because of tds creep and will lower as it runs. Non-exhausted DI resin should give you 0 TDS coming out. The membrane itself will typically last 3-5 years, sometimes even much longer. DI resin doesn't really have a "normal" as it is completely dependent on your source water. Monitor the TDS and when it begins to go above 0 then it is time to change the resin. We use a color changing DI resin so this should also coincide with the resin turning from a dark blue/black color to a gold/yellow color. -
by BJ on September 4, 2013, @5:12 PM
What were to happen if you put a membrane at a different rate than the unit is mark at? For example, putting this 75gpd into a 50gpd RODI unit or putting a 90gpd membrane into a 75gpd unit? They all seem like the same plastic enclosures. Does the membrane just really dictate the GPD output?
Bulk Reef Supply Hey BJ,
If you change the size of the membrane without changing the flow restrictor to the proper size your unit will have the incorrect amount of waste water. It will either have too little water which would damage the membrane or too much water, which is just a waste of water (and could decrease pressure). The housings for the membranes themselves are universal. The membrane is what changes the output, though there are some other factors such as water pressure and temperature that do as well.
75 GPD MEMBRANE (98% REJECTION RATE) Hands down the best membrane for our hobby.
Compatible with all RO systems
FILMTEC reverse osmosis membrane elements for home drinking water are the industry's most reliable. Advanced membrane technology and automated fabrication allow these elements to deliver consistent performance that equipment suppliers, water treatment dealers, and residential customers can rely on. FILMTEC elements are shipped dry for convenient handling and long shelf-life. These elements are NSF/ANSI Standard 58 listed. Equipment suppliers can take advantage of FilmTec's Standard 58 listing and participation in the NSF Data Transfer Protocol to reduce costs for reduction claims for their systems.
- Rated at 50 psi
- Will purify about 20% more water than competitive elements rated at 60 psi
1. Permeate flow and salt rejection based on the following test conditions: 250 ppm softened tap water, 77°F (25°C), 50 psi (3.4 bar), and 15% recovery.
2. Permeate flow rates for individual elements may vary +/-20%.
Deal of the Day! BRS Coral Propagation Kit – Standard
Ends inRegular Price: $24.99
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I am planning on going to ski on Fri. the 13th, do not know how to put on chains and remove them, is there any public transportation ? or some kind of group I can join ?
Thanks for help
I need driver door 4 door chevy Impala, Biscayne or Belair
I'm staying in the village over thanksgiving. Where can i rent equipment and go snowshoeing?
As the title says - how easy is it to take the Metro in LA, and how reliable is it? We're going for the Rose Bowl and considering staying in the downtown area to be able to take the metro to the stadium. Is that going to be feasible?
I've used metros in Chicago, New York, and London before - how does LA's compare to these? Also, any advice on cheapest way to use it? Is there a day pass or anything? Any kind of deals that might make sense for someone who is only going to be in town 2 days?
How can I safely go to Wrightwood to ski on Dec. 13th Fri. not worrying about chain install and remove ?
does anyone know good places to walk/hike with my friend in a wheelchair who I am visiting this week? thanks n aloha, j-me
My son and his wife are currently living in Redding. They will be moving to Chico in about a month. We all love the outdoors and we love adventures so I thought I would buy a gift certificate for an adventure in the chico area. Maybe one of you has an idea. My budget is around $200.00. If someone know of a tree house rental I would love to hear about that. Thanks - Sue
We plan to take a cab to the Parsons lot and catch a shuttle to the Rose Bowl. Are there cabs available near the Parsons lot after the game?
Quick question is their any way that i could get public transportation fron la mesa to the Miramar Air station?
My husband says "let's go to the Grand Canyon" for our 20th anniversary. Well in doing all my research, I learn the location (and existence!) of Sequoia and now I just can't imagine being so close and not seeing the trees...
We fly into Vegas April 10th, arriving at 11:40am. We are to return home April 18th, leaving at 10:55pm. These are the only plans I have set so far. Got airfare from Maryland for $300 a piece.
I've tried to map loops to keep us going in one direction without backtracking and was hoping I could figure 8 these in...
I've even thought about flying into someplace in California and starting there...
My initial plans were touring completely just east of Vegas, but after discovering Sequoia...
Most years we vacation in the Smokey Mountains of Tennessee, so this area seems more like us than the things east of Vegas, but I also know I need to see these places during my life!
Can they be done in 9 days without my entire family (two kids, 11 & 12 and DH) hating me from all the time on the road?
Thank you so much for your time! I look forward to the replies!
It's a close family members birthday coming up. I want to pay for their trip on a cruise to mexico from LA. How can I book their trip and pay for it without myself being on the trip?
I'm in the area on business and staying in Claremont. I have tonight free and would love some suggestions on something to do. I went to the village last night (really stayed on the street that Hero's is on). Other suggestions?
do any tour companies pickup at Laguna Beach, mainly tours to LAX, Hollywood area?
I know we can take from Anaheim but was hoping to avoid doing that
what's the easiest,fastest,most affordable way to get to Anaheim without a car rental?
We're flying United from SLC to LAX on 1/29 arriving at 7:05 am @ Terminal 8. Our Hawaiian Airlines flight is at 8:40 am from Terminal 2. I know we'll have to exit the airport and go back through security — and they won't transfer our bags, so we'll have to do that ourselves.
Originally we had almost 2.5 hours between flights, but both airlines have changed their times. I'm a little stressed and United won't let us switch our flight to the day before.
Someone had suggested exiting baggage claim at Terminal 7/8, getting a cab to Terminal 2. Then using the Skycap services — or Hawaiian Airlines web check-in bag drop — to expedite that process.
Does anyone have a sense of whether this is possible?
How do i get there faster without using the 534? Someone Help please
Three mates and I have managed to break free from our wives in July 2014 to do the route 66 tour. At the completion of the tour we have decided to stay in Los Angeles for 4 days before flying home to Australia. Can anyone help with best location for accommodation (not too expensive) and places we should priorities to visit, regards Lance (By the way our age group is an active 65 to 70)
How can I find a guide who knows Turkish in between 14 March - 22 March 2014 in Los Angeles?
Is it a good idea to explore the city on bicycle?
what to wear in december at a convention in san jose
Planning a trip in late May. Where is the best place to stay -- luxury level - and still be in the thick of the action?
Michigan State just clinched a spot in the Rose Bowl last night! So I'm looking into how to get to Pasadena for the game. The thing is, we are driving back from Michigan to Maine the weekend of the 28th-29th, so it's entirely feasible that I could get dropped off to fly out of any airport along the way. Any of these airports would be possible to fly from: Toledo, Cleveland, Erie, Buffalo, Rochester, Syracuse, Albany, Worcester, Boston, Portsmouth, or Portland.
I've also heard there are a lot of other airports besides LAX to fly into (ONT, SNA, LGB, BUR, etc.)
So, trying to look into all possible combinations to find the cheapest flight seems pretty daunting. Anyone have some advice on which two airports might have the cheapest fare between them? Boston to LAX seems a likely candidate, but how about any others?
It's off the beaten path -- small B & B on sand beach; does weddings. Do you know the name?
any bookstores beside channel island and victoria avenue
Hi all, my family of 6 will be taking two cabs to the Golden Gate Bridge from Lombard Street and from there, we will walk onto the bridge itself.
As we are travelling with young children, I would like to ensure that we meet at the best place possible.
Could you kindly advise on what is the best meeting point for our 2 cabs and what address do we tell the drivers?
May I also know where can I buy phone SIM Cards?
Thank you so much.
Does Hemp and Chocolate handle mail orders? Do they have an internet address?
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Sami asks what's next for industry and how do we get there?
Ulf Ewaldsson, Ericsson's Chief Technology Officer discusses how ICT technologies can transform industries.
David Holecek, Connectivity Brand and Marketing Manager, Volvo Car Corporation, discusses his own and Volvo's thinking behind the Connected Car.
In a new blog from Ulrika she looks at the issue of cities and say if we can solve them, then we'll solve many of the problems of the world too.
Mikael Eriksson Björling looks at how work will be organized in the Networked Society.
In this Tech Talk, Erik Dahlman, Senior Expert in Radio Access Technologies within Ericsson Research talks about 5G or fifth-generation radio access, what it is and what we believe it will bring us.
Ericsson Ltd. - Unit 4, Midleton Gate - GU2 8SG Guildford -United Kingdom -Phone: +44 1483 30 36 66


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Hire Dancers in Lafourche County, LA
Select your location below to browse talent near you.
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So, you think you can dance? We're sure you can... but how good? We all like to turn the music up and get down in the privacy of our own homes or in the masses of people at the clubs. But when it comes to dancing in front of the people you've invited to your event, you might want to leave it up to these professionals. From hip hop to ballroom to belly, these dancers have perfected all the moves that will impress your guests much more than you'll be able to.


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Writers, musicians, illustrators, photographers, video editors artists of all kinds are invited to contribute their work to hitRECord. Once on the site, the hitRECord community collaboratively edits, builds upon, develops and remixes each others work to create songs, animation, short films, live shows, music videos you name it!
As certain community collaborations develop at hitRECord we figure out ways to get our artwork out into the world. Since 2010, hitRECord has put out works of publishing and music, gone on tour and screened at festivals. And now, we're working on producing a TV variety show!
Now, the point of hitRECord isn't to make money. A wise man once said "we don't make movies to make money; we make money to make other movies" and that's why hitRECord is a for-profit company. If and when we're able to earn money from one of our hitRECord productions books, live shows, vinyl records we split the profits 50-50 with the artists who contributed.


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Euroweek Issue 1207 - 3 June 2011
Dealogic is a global software firm providing information systems and solutions for the investment banking industry.
Dealogic Analytics offers global coverage of the investment banking and financial sponsor markets allowing users to keep informed real time of all deal related activity. Dealogics systems are used extensively for marketing and competitor analysis and allow for detailed analysis of industries, regions, products, pricing trends and transaction structures as well as for senior level strategic planning.
EuroWeek has a long standing relationship with Dealogic having exclusively published Dealogics bank rankings for many years. These rankings have become a barometer for the industry and a benchmark for banking performance. Included below are links to the most up-to-date rankings for DCM, ECM and the MTN Markets. Also below are links to Dealogics ranking methodology and comprehensive ranking criteria.
DCM Official Ranking Criteria 2011For more details regarding rankings please contact Dealogic directly on +44 20 7379 5650 or email firstname.lastname@example.com.
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