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Maverick McCain Picks Gov. Sarah Palin as his Running Mate
The Maverick has indeed gone bold.He has just infused this 2008 presidentail campaign with a jolt of raw energy.Sarah Palin is the Vice Presidential nominee of the Republican Party.
In this Dec. 4, 2006 file photo, Todd Palin, right, holds the Bible for his wife, Sarah Palin, as she is sworn in as Alaska's governor during an inauguration ceremony in Fairbanks, Alaska. As the political community turned desperate for any clues about the potential running mate of Republican Presidential candidate, Sen. John McCain, R-Ariz., speculation moved toward several dark horse candidates including Alaska Gov. Sarah Palin, the so-called 'hockey mom' credited with reforms of her tiny, out-of-the-way state.
There was a flurry of reports from the pundit class in the wee hours of the morning indicating that Senator John McCain was going to choose Governor Sarah Palin of Alaska, the first female Governor of that State, and a rising star in the new face of the Republican Party, as his Vice presidential running mate.
She rose to prominence through her courageous willingness to expose ethics violations within her own State Party. She is pro-life, pro-marriage and family, and pro-freedom. She is a happily married wife and mother of five children. She is beautiful, well liked in her home State (80% approval rating), articulate and from all that I have heard, a genuinely warm,kind and good person.
The suspense over the pending announcement was unlike anything I have experienced in all my years of political participation and activism.
Now, it has been confirmed. The McCain/Palin ticket will soon take the stage. The Maverick has indeed gone bold.He has just infused this 2008 presidentail campaign with a jolt of raw energy. The entire Press corps is fixated on the Republicans this morning, even though Senator Barack Obama gave his much anticipated acceptance speech last night.Senator John McCain turned 72 years old today. With this historic decision he has proven that he still has a lot of life and courage. More, after the historic introduction.
Pope Francis Prayer Intentions for December 2013
General Intention: Victimized Children. That children who are victims of abandonment or violence may find the love and protection they need.
Missionary Intention: Prepare the Savior's Coming. That Christians, enlightened by the Word incarnate, may prepare humanity for the Savior's coming.
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1 - 10 of 20 Comments
5 years ago
One cannot be pro-life if they are anti-abortion for the death penalty and war... OR pro-abortion and against the death penalty or war. I am pro-life from conception to natural death. Another human shall not take another human's life at all!
5 years ago
I am a Canadian woman, caregiver to my 57 yr younger sister with Down's. She is also perfect and pure. I wish I was allowed a vote in the U.S. election. The ticket would certainly be the McCain/Palin one. Bravo to both of you. Lookin forward to your inaugurals. God bless
5 years ago
Nothing about the fact she abandoned the Church?
5 years ago
This is far from a "maverick" pick. It's the same old, same old from the Repubs. Pick someone to rally the hateful evangelicals and the pro-murder, but anti-abortion right wingers who voted for Bush. Just shows McCain is as cowardly and cynical as Bush and co.
5 years ago
As an adoptive parent-I say thank God for Sarah!! My children's birth moms didn't abort-as a result-I am a parent!!!! You can't know what that means!
5 years ago
I am a cradle Catholic. I have been a democrat all my life because I always thought the republican party is the party of the rich and well connected. In Matthew 25 scriputre tells us "I was hungry and you gave me to eat, I was thirsty and you gave me to drink, a stranger and you welcomed me, naked and you clothed me, ill and you cared for me, in prison and you visited me. There is more than one issue in this election, health care, education, the environment, capital punishment, the war in Iraq where thousands of innocent civilians were killed but I guess that is all right because they were not babies. How can you reconcile the Republican agenda to scripture. As proven by the last 8 years, the Republicans are for big business, big oil, drug companies, big tax breaks for corporations and rich people. Isn't it time to do something for the middle class?
5 years ago
Sarah Palin is qualified to be Vice-President. Her skills and qualifications far outstrip the Democrat Candidate Barack Hussein Obama. She is Pro-Life, for Small Government, Tax Cuts, and has helped reformed her state from the corruption of her own party (she bears some similarities to the great Cardinal Cisneros of Spain). Thank you Lord.
5 years ago
Sarah Palin is wholly unqualified to be President, and makes Barack Obama by comparison, look like an experienced statesman. But Governor Palin will help overturn Roe V. Wade and insure that wealthy women will once again have to board a jet plane to have their abortions, while we Catholics can revel in the arrest and jailing of those poor women fortunate enough to survive what will be the return to the 'back alley' abortions of yesteryear. Truly a great moment for followers of Christ, and Proponents of Rich women. . . . Poor women ? ? ? not so much.
5 years ago
Hooray, for Sarah Palin!! It is about time, of which we have a voice, against abortion. I will vote for McCain, and
Palin. I am proud to be a Catholic.
Jerry Dalton, Jr.,
a deaf person
5 years ago
Sarah is also pro death penalty and pro creationist-teaching.
So if she were Catholic, guess she'd be heading to the cafeteria for lunch, huh?
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Straggling cross-country back to his native Peoria, Daniel Noe followed his vagabond spirit.
The Northwestern University student had spent the summer of 1978 hiking and working in Washington state. Before returning to studies that fall, the 22-year-old called his father to say he'd first stop for a visit home. His father offered to wire bus fare, but conventional travel didn't suit the free-spirit who liked to thumb rides.
"I'll get back faster in my roundabout way," he cheerfully told his dad.
That was on Sept. 30, 1978. His parents, Ray and Phyllis Noe, never heard from him again.
They will say goodbye next week at a funeral mass in Washington, Ill., where his parents now live. Chicago investigators, in a twist while looking for more victims of serial killer John Wayne Gacy, discovered Daniel Noe had died accidentally on a mountainside in Utah.
On Sunday, a Chicago detective drove to his parents' home in Washington to tell them the news. The Cook County Sheriff's Department made an announcement about the Noe case Thursday.
"It's good to have a conclusion," his mother said Thursday. "Of course, it would've been better if he had been found alive."
At Peoria (Central) High School, Daniel Noe was on the chess club and the debate team. He enrolled at Northwestern to study medicine and become a doctor.
After the 1978 spring term, Noe headed out west to encounter nature. He found a place to stay in Bellingham, a town in northwest Washington state not far from Vancouver, British Columbia. In Bellingham, Noe worked as surveyor and factory worker. Off hours, he'd backpack, bicycle and explore all summer until he had to go back to school.
After his final call home, his parents began to worry after not hearing from him again for two weeks. His friends could offer no clues, nor could officials at Northwestern. They contacted Bellingham police and Illinois State Police. That December, they filed an official missing-person report.
By then, they figured he likely had died on the way home. For decades, they never received any further information about their son's whereabouts.
Periodically, they would get phone calls from collectors seeking payment on Daniel Noe's college loans. Though his parents explained the disappearance, the calls kept coming for 20 years.
"If you can find him, let us know," they sometimes would tell collectors. "No one else has been able to."
Despite the lack of news, they allowed themselves a sliver of a possibility that he somehow, somewhere was still alive.
"There's always a chance," his mom said. "You don't give up all hope."
Page 2 of 2 - Seeking answers, the family turned to the lingering investigation of John Wayne Gacy, executed by the state in 1994. The Cook County man murdered at least 33 people from 1972 to 1978.
However, several victims remain unidentified to this day. Last October, the Cook County Sheriff's Department announced a new push to make identifications via new DNA profiles of the remains. Families of missing persons nationwide flooded Cook County authorities with requests to attempt genetic links.
One of Noe's siblings saw a TV report about the renewed investigation. Noting Northwestern's proximity to Gacy's home, his family pondered the chance of a tie to the serial killer. So, his parents provided a DNA sample to Chicago detectives.
The tests proved negative, but detectives offered to feed the family's DNA profile into a nationwide forensic database. Recently, police made conclusive ties between the Noes' DNA and remains found in 2010 on Mount Olympus, Utah. No foul play is suspected in Noe's death, according to the Cook County Sheriff's Department.
Until Sunday, the family had no idea about that 2010 case. In fact, after the Gacy tie proved negative, his parents figured the DNA effort would go nowhere.
"To be honest, we didn't suppose that they'd find anything," his mother says.
A visitation for Noe will be from 5 to 7 p.m. Monday at Deiters Funeral Home & Crematory in Washington. A funeral mass will be held at 10 a.m. Tuesday at St. Patrick Catholic Church in Washington. Burial will be at Resurrection Cemetery in Peoria, as Daniel Noe finally goes home, for good.
PHIL LUCIANO is a columnist with the Journal Star. He can be reached at firstname.lastname@example.com, facebook.com/philluciano, 686-3155 or (800) 225-5757, Ext. 3155. Follow him on Twitter @LucianoPhil

subset: commoncrawl


text:
Delivery within 3-7 working days
Patterned bandeau style bathing costume from PHAX SWIMWEAR. Thin halter neck that ties behind the neck. Decorative ruffles in a contrasting pattern along the upper edge at the front. Cups with removable padding and ties to the reverse. Elastic under the bust. The bottom in the briefs shape. Cut outs at the sides and rear. Lined inside. Hand washing is recommended.
Made of 93% Polyamide and 7% spandex.
Item no.: 723088-0061
Colour: Pink/Green
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Leadership vs. Management |
Welcome to Private Duty Today! . . . the bi-weekly electronic newsletter for Private Duty Home Care Leaders from Leading Home Care . . . a Tweed Jeffries company. In this issue, we bring you ideas, information, and insights to help you grow your Private Duty Home Care business. Private Duty Today! is a permission-based newsletter. It is only sent to our recent customers and those individuals who have requested it, or who have given permission for their address to be included on our list of subscribers. Jason Tweed, Editor
In Stephen Tweed's Leadership Academy Learning Guide, he describes management as "the tools and techniques to make an organization run. It is tasks, structures, and systems. Management is about budgets, performance indicators, charts, scheduling and financial reports. Management is about predictably, order, control and problem solving. Management produces short term results." "Leadership is the process of influencing others." says Elizabeth Jeffries in her book, The Heart of Leadership: Influencing by Design. "It is about establishing direction, outlining people to move in that direction, motivating and inspiring people. It is about serving, and it produces long term change." Finding the balance between these two distinctly different skill sets challenges many home care executives. I talk to owners daily who are terrific managers. They have the skills and procedures established to run efficient private duty companies, only to find themselves growing beyond their abilities to manage. Now they are faced with becoming leaders and empowering others to manage the daily tasks. This transition can be challenging. Conversely, I spoke with a potential coaching client yesterday. When I asked the newly hired Executive Director about her goals, she said she needed to understand the business of private duty better. She'd been a successful senior level leader at a large home health care company, and realized upon taking this new position that non-medical home care operates very differently. Having strong leadership skills made her aware that she would falter as a leader if she didn't have a strong understanding of the daily operations.
Here are a few tips to help you find your leadership and management balance. Don't micro-manage. Effective leaders empower their employees to achieve a task, or sometimes conquer a challenge. Get as much information as you can so you clearly understand the tasks, structures, and systems that help your company operate, then offer guidance and suggestions to those charged with implementing. Learning about the tasks of the people you lead helps in three ways:
Lead by learning. Elizabeth Jeffries says "Leaders Are Readers". Learning to manage tasks and systems is natural, simply because as you manage daily operations, you gradually improve and become more efficient. Leadership, however, is more difficult to improve. Simply leading, or attempting to lead, isn't enough. Strengthen your leadership skills by reading, listening, attending seminars, and becoming a student of other leaders. Some people say "I don't have time", but if you've already made time to read this far into this article, that's a step forward. Find ways weekly to study leadership. Ask yourself this question. "Is my goal for this situation a long term solution or a short term fix?" One of the critical differences between leadership and management is the duration of the effect. Managing a task affects your business for the short term. Leadership takes longer, but also affects your company for a much longer duration. An upset customer is often a management issue, and needs to be handled quickly, while an employee experiencing challenges on a job is more likely a leadership issue, requiring investment of time to ensure long term value from the relationship. Finding the balance between being a manager and being a leader seems more difficult than it actually is. Management, being about tasks, and leadership, being about influence, are so different that once you understand these differences, deciding to manage or lead becomes significantly easier.
Stephen Tweed Updates Us from Chicago As you read today's newsletter, 25 home care leaders from across the country are gathered in Chicago for The Academy for Home Care Leadership. This two day intensive learning program is focused on The Top Ten Competencies of Highly Effective Home Care Leaders. The group includes owners of Home Care agencies such as Lucil McCormick, owner of Attentive Services in Sherman Oaks, California; Karen Cromie, owner of Care for Better Life in Frankenmuth, Michigan; Delma Chavez, owner of St. Joseph Home Health in Odessa, Texas; and Brian & Susan Platt, owners of Spoon River Home Health in Farmington, Illinois. On Tuesday, the group discussed each of the top ten competencies. Then they looked at "Seeing the Bigger Picture." Our leadership research showed that the single most important characteristic of highly effective leaders is the ability to see and understand the bigger picture of home care. The group discussed the forces and trends shaping the future of home care, overall business building strategies, and the seven sources of competitive advantage. The afternoon session focused on planning; Strategic, Operational, Program, and Financial. Then they looked at how to set priorities and manage time, how to avoid distractions, and how to set SMART goals. In today's session, they'll be working with Elizabeth Jeffries to explore the culture of the organization, understanding leadership styles, and inspiring others to follow you. We'll close the day with how to create a great place to work, how to find and keep top talent, and how to coach problem performers and behavior problems. You, too, can experience The Academy for Home Care Leadership. We'll be in Orlando, Florida on January 18 & 19. Now's a great time to make your reservation and fly south for some fun in the sun, and some leadership learning. We'll see you in Orlando.
The Heart of Leadership: Influencing by Design By Elizabeth Jeffries, CSP, CPAE In today's competitive marketplace, managing isn't enough! The challenges facing organizations now require leadership to survive, grow, and prosper. The Heart of Leadership: Influencing by Design is a book about leading on purpose, not by accident. The Heart of Leadership empowers readers and teaches them how to create an environment that increases productivity and profitability in the organization, more effectively serve their customers and gain a deeper sense of personal fulfillment from their work.
Private Duty Today! is published every other Wednesday by Leading Home Care . . . a Tweed Jeffries company. We invite you to pass this newsletter along to your friends and colleagues in Private Duty Home Care by clicking on the link below.
Permission to Reproduce: Permission is granted to home care companies, home care associations, and home care related publications to reproduce articles from this newsletter as long as appropriate credit is given as follows: "Printed with permission from Private Duty Today! Copyright 2004 Leading Home Care ... To sign up for your FREE Subscription, log on to www.leadinghomecare.com." You may also sign up for your FREE Subscription to Stephen Tweed's Leading Home Care Report. This bi-weekly electronic newsletter is written for home care company CEOs and senior executives who want to grow their businesses and multiply their performance.


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Use the Nokia phone selector.
Smile 2012
by: intheme c.studio
Themes - 2.52 MB
High quality theme including 3d vector icons and stylish vector menu items, comfortable colors. Creative authoring wallpaper and backgrounds. Optimized for portrait and landscape modes. This theme is not only beautiful but also practical and convenient to use.
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View gallery in plain HTML
fiesta crash image
Ford Fiesta - 3/4 front (driver)
Important note: The 1.4 litre European model was tested by EuroNCAP. Australasian specifications may vary and therefore models sold in Australasia might provide different levels of protection to those described on this page. The Fiesta has a 1.6 litre engine in Australia. The external dimensions of the 1.4 litre and 1.6 litre engines are identical.
The Ford Fiesta scored 10.98 out of 16 in the offset crash test. The passenger compartment held its shape well. Protection from serious chest and leg injury was marginal for the driver.
The vehicle scored 13.86 out of 16 in the side impact crash test. There was a moderate risk of serious chest injury for the driver.
The safety feature information below is subject to change without notice. For up to date safety feature specifications for all variants, please see the safety feature table to the right or contact the manufacturer.
The Ford Fiesta was introduced in Australia during 2004.
Dual front airbags are standard equipment. Side airbags, headprotecting side curtains and ABS brakes are available on some variants. The front seat belt buckles are mounted on the seats and the upper anchorages are adjustable.
These features improve the fit of the seat belt. Pre-tensioners are fitted to the front seat belts to reduce slack in the event of a crash. A three point seat belt is fitted to the centre rear seat. This provides better protection than a two point seat belt.
The passenger compartment held its shape well. The brake pedal moved rearwards by 98mm and the clutch moved upwards 9mm. The steering wheel hub moved rearwards 44mm and upwards 31mm. The front ("A") pillar moved 15mm rearwards. The width of the driver's doorway shortened by 9mm. All doors remained closed during the crash. After the crash high manual effort was required to open the driver's door.
The airbag cushioned the head of the driver and contact was stable. Steering column components were a potential source of injury for the driver's knees. The passenger's head was cushioned by the airbag.
The Australasian New Car Assessment Program (ANCAP) provides consumers with independent and transparent information on the level of occupant and pedestrian protection provided by different new car models, in the most common types of crashes, through its star rating program.
The vehicle was not eligible for a Pole Impact Test since it did not have head-protecting side airbags. This test can earn eligible vehicles an extra two points.
A separate pedestrian impact test is conducted. This test estimates injuries to pedestrians struck by a vehicle travelling at 40 km/h. The more stars the better (maximum 4 stars).
Electronic Stability Control (ESC) helps drivers to avoid crashes by reducing the danger of skidding, or losing control as a result of over-steering. Australian research shows that ESC reduces the risk of Single car crashes by 25% find out more ...
Curtain airbags are designed to protect the driver's and front seat passenger's heads in a side impact crash.The curtain airbag activates instantaneously, deploying from the top of the door rails above the side window. They form a cushion between the driver or passenger and the window and stay in place if the car rolls over to protect their head.
Curtain airbags are designed to protect the driver's and passenger's heads in a crash. The curtain airbag activates instantaneously, deploying from the top of the door rails above the side window. They form a cushion between the driver or passenger and the window and stay in place if the car rolls over to protect their head.
Also known as Adaptive Cruise Control, Active Cruise Control detects the distance and speed of the preceding vehicle and maintains an appropriate following distance.
Traction Control systems optimise grip and stability of the car on the road during acceleration by measuring wheel rotation. It stops wheel spin by reducing engine power or temporarily applying the brakes to that wheel, allowing the car to accelerate smoothly, even on slippery surfaces. Limited slip differentials also help provide a more even distribution of traction forces when the car is on a slippery surface.
ABS (Antilock Braking System)reduces the risk of tyres skidding under heavy braking and allows the driver to maintain steering control of the car. ABS only operates under heavy braking or on slippery surfaces.
Adjustable steering columns allows for steering wheel heights to be adjusted to the driver's preference.
Fog lamps have a low, flat, fan shaped beam designed to improve the driver's ability to view the road. Fog lamps must only be used in low visibility conditions such as fog or snow.
Drivers' airbags or frontal airbags typically deploy from the steering wheel to protect the driver from striking other parts of the car in a frontal crash. Drivers' airbags are designed to be used in conjunction with seatbelts and do not offer protection in the event of a side impact crash.
Pretensioners tighten and reduce slack in seat belts to protect occupants from rapidly moving forward in the event of a crash.
Pretensioners tighten and reduce slack in seatbelts to protect occupants from rapidly moving forward in the event of a crash.
3 point seat belts are belts that goes over the waist (lap) and the shoulder (sash) of the occupant. 3 point seat belts provides better protection than 2 point seat belts (lap belt only).
Choose a car that could save your life.
If it doesn't have Electronic Stability Control (ESC) and Curtain Airbags cross it off your list.
ANCAP today awarded Skoda's new Octavia a 5 star safety rating. The Octavia joins the Roomster, the Superb and the Yeti to give Skoda a fourth 5 star safety rated car for its Australasian fleet.


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Our Mission is to provide exceptional, compassionate veterinary care and excellent customer service to conscientious animal owners in the foothill communities and along Denver's front range. In addition to complete mobile and in-house veterinary services, we take pride in providing advanced Equine Dentistry, Animal Acupuncture & Animal Chiropractic services at your location or ours. Aspen Creek Veterinary Hospital treats equine clientele, llamas, alpacas, cattle, goats, sheep, pigs (including pot-bellied) in addition to comprehensive small animal service (dogs, cats, etc.). Mobile veterinary services, Animal Chiropractic, Animal Acupunture and Equine Dentistry Services are offered to clients in the foothill communities and all along Denver's front range. Hospital services are available to all clients wishing to transport to our facility in Conifer.
Congratulations to Dr. Olds! Dr. Olds recently completed certification and board examination to become recognized as a Diplomate of the American Board of Veterinary Practitioners in Equine Practice. To become a Diplomate of ABVP is a rigorous and demanding process that requires the completion of a residency program or equivilent practice experience, submission of case reports, veterinary colleague references, extensive continuing education credits, and finally passing a two day written and practical certification examination.
Second Annual Performance Horse Seminar
Sunday February 23rd
8:00 am - 4:00 pm
Location: Jefferson County Fairgrounds
Great speakers, cutting edge topics, & live demos.
We will will sendind out official programs and invites soon!
Animal Chiropractic Service: Shannon Harland, DVM is IVCA (International Veterinary Chiropractic Association) certified in Animal Chiropractic care for both large and small animal patients. Chiropractic care can be very beneficial for a wide range of issues in dogs and horses. To schedule an appointment or for more information, please feel free to call the office. Animal Acupunture: Aspen Creek Veterinary Hospital is now offering animal acupuncture services. We believe that a combination of traditional and non-traditional treatments can truly benefit some patients. Animal acupuncture may beneficial effects for a variety of conditions in horses, dogs, and cats. Some of the specific issues that can benefit from acupuncture include: peripheral nerve paralysis or nerve damage, intervertebral disk disease, arthritis pain, incontinence, irritable bowel dysfunction, neck or back pain, hot spots, chronic renal failure, megacolon, urinary tract inflammation, and more. We have a veterinarian trained and certified by the International Veterinary Acupuncture Society available for consults and treatment sessions. If you would like more information about this service, please feel free to call. Did you know Aspen Creek offers a complete line of supplements and prescription veterinary diets: We are distributers for EquiPride and Platinum Performance for horses as well as Royal Canin, Purina and Hill's Prescription veterinary diets for dogs and cats. Some items need to be special ordered, so please call ahead.


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BE And NDS Showcase HD Radio Conditional Access At NAB2007
BE, a leading manufacturer of HD Radio broadcast equipment, and NDS, which specializes in conditional access technology, will bring the controlled-content experience to
"We are pleased with the cooperation between NDS and Broadcast Electronics on bringing our conditional access solution to HD Radio broadcasting," stated
The demonstration will take place at NDS booth N7137, and showcase the integration of the NDS conditional access system into BE's HD Radio IDi 20 Importer unit, broadcasting program content addressable to receivers meeting access conditions.
"We very much view this as a partnership of technology and people that will have tremendous impact on the future of radio. Conditional access is one of the cornerstones of HD Radio broadcasting's growth because it has so much potential, not only for the delivery of audio programs but also the delivery of data services," said Ray Miklius, BE Vice President Studio Systems, who is presenting a technical paper on infrastructure for conditional access and other HD Radio advanced services at the
Access to specialty content and programming for niche markets, including reading services for the blind that have relied on expensive SCA technology in the past, are just a few of the opportunities open to broadcasters using conditional access for new multicast channels.
At booth N7106, BE will show its HD Radio transmission equipment with new interface as well as other advanced HD Radio services such as electronic program guide (
About Broadcast Electronics (www.bdcast.com
Broadcast Electronics (BE
About NDS
NDS Group plc (NASDAQ: NNDS), a majority owned subsidiary of News Corporation, supplies open end-to-end digital technology and services to digital pay-television platform operators and content providers. See www.nds.com for more information about NDS.
# # #
®Broadcast Electronics and the Broadcast Electronics logo are registered trademarks, and Messagecasting is a service mark of Broadcast Electronics Inc. HD Radio and the HD Radio logos are trademarks of iBiquity Digital Corporation. All other trademarks are property of their respective owners.
Kim Winking
Phone: (217) 224-9600
Fax: (217) 224-9607
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text:
Rep. Anna Eshoo's (D-Calif.) bill that would require broadcasters to turn down the volume of TV commercials easily passed the full Commerce Committee today. It now heads to the House floor.
Under the bill, the FCC would come up with recommended volume standards. Broadcasters would then have a year to acquire the equipment they need to bring loud commercials inline with those standards.
More information can be found in this previous story.
Alec Ross: U.S. telecom policy not admired abroad
GOP leads new media charge


text:
Howdy All!
As soon as 1.6.2 is released, I'll be working on updating our entire server network to 1.6.2. During this time the WoM network will be unavailable to all players
Watch this space for updates and more information
Please login to view downloads!
so your going to shut down the mc network while you wait?
Updates :D and ssfdre I think so yeah
During this time the WoM network will be unavailable to all players
During the updating time. He's not going to wait till 1.6.2 comes out :/
Read silly.
hey guys im running minecraft 1.5.2 but the lagging problem is big.i re updated minecraft,i updated java, i chenged fog to tiny but nothing!!!!!!! still lagging.Ive looked for viruses [no virouses]. the first 6 months minecraft was working perfectly :(
Its can just be your network itself so check that
How long will the server most likely be down? A week?
few hours... if that
lol, it would never be down week just for a update.
Just askiing :P I was told if things were bad it could last a week lol
Yeah I heared the same thing bronze heard. Someone said 1-2 weeks
This sounds awesome! By the way, I know I have asked in the past, but with the hub world and all and a pvp arena in the hub world, would it be possible to have a kit pvp type thing where people could choose kits and pvp it out?
I had the same problem. Open up task manager and check the CPU usage. Close any unwanted programs. Worked for me
your pic Shazty,Monster cat :3 also 1.6.2 is out, any thing about the update?
Nothing random_ninja14 :3
What took so long?
Snow had a pressing appointment in my bedroom...
A small monkey crawled into the server and started pulling out wires
The hampster we use to power the server with ran out of steroids so we had to wait for a bit.
We were journeying through space and time and misjudged the landing
The server tried to hold onto it's version and we had to beat it into submission...
one or all of those
You know, spud, if your hampster ran out of steroids I have heard that potato batteries work quite well.
spudsrus thats a good enough explaination you know.
I was in the hub when the server shut down..
it says outdated server..
Help? :O
This just in! With the coming of the 1.6.2 era, many players are executing a mass exedous to the dangersous unchartered territory commonly known as the unloaded chunk zone searching for a mythical creature known as 'horse.'
Come join the pilgrimage to the horseland.
Snow had a pressing appointment in my bedroom...
Not enough info, spuds :l
This just in! With the coming of the 1.6.2 era, many players are executing a mass exedous to the dangersous unchartered territory commonly known as the unloaded chunk zone searching for a mythical creature known as 'horse.'
It took a world record of 6 seconds before someone asked where to find a horse.
please I want to join the pilgrimage!
I dont know how...
Meh? I found horse paradise already!
It took a world record of 6 seconds before someone asked where to find a horse.
Now that the server's 1.6.2 we for some reason can't go to the lobby. It says outdated server.
using play.womjr.com?
Im currently trapped there :P
Is there an Ip specifically for the hub?
i was on the hub just fine for me
Why can't i join the hub? all it says is "hub is outdated"
the sever has updated to 1.6.2, nuff said
Lock this, it's getting to off topic, if any of you guys need help, PM staff or make another forum topic.
Doesn't seem 1.6 since it keeps saying its outdated when I try to connect.
I don't see why I have a stable with over 20 horses. you need to go into "edit profile" then click the version you want, then hit "save changes" or something like that.
I have the update, It just won't let me connect. I get the "Hub is outdated" message everytime I try to connect.
Well thats the HUB, idk if they have updated that or not.
Was anybody else at the Monstercharity?


text:
Mark on Money
Four days of great cycling are getting underway for this year's Gateway Cup. Race Director Amy Strahan has all the details.
Total Information PM
What was happening around the world in the week before 9/11 ten years ago? Boston Globe columnist Joan Wickersham tells us about her column, "Nine Days Before the Sky Fell."
Total Information PM
Coming to Sauget, IL on September 24th is Ruckus St. Louis! One of the organizers is John Merry and he fills us in on the big event.
Total Information PM


text:
It took just five minutes for the Palestine boys' soccer team to open the scoring against Waco in their sectional round boys' soccer playoff game Friday, but for all their possession, they could not make that early lead stick as the Lions ran out 3-1 winners.
Palestine's players, try as they may, just could not fashion a clear-cut chance as they repeatedly drove forward into the Waco half, but could not find the way past the defense a second time.
Palestine opened the scoring when the ball was played across from the right and a step-over left it free for Alonso Cruz to put his foot right through the ball and blast into the net to make it 1-0 to the Wildcats.
Then, in the ninth minute, Cruz ran menacingly down the left and played the ball into the center for Wes Ives, but he dragged his shot wide of the right upright.
Waco then took full control.
With 16 minutes gone Jason Diaz leveled matters. There seemed to be nothing on when he picked the ball up 40 yards from goal, but Diaz dribbled skillfully past three defenders and carried on going, before slotting low into the net to tie the game at 1-1.
With 26 minutes gone, Waco almost took the lead when Diaz, standing just 10 yards out, looped a header over Palestine goalkeeper Jose Cabrera. But, the Palestine keeper managed to push the ball onto the crossbar with his fingertips. Hiram Williams then flashed a shot just wide from the angle.
The siege continued on the Palestine goal when Jason Diaz turned inside a defender and shot against the crossbar from 20 yards out.
Seconds later, he went one better when he took the ball outside the defender and took a touch before unleashing an unstoppable right-footed strike that flew like a bullet into the top left-hand corner of the goal to put Waco 2-1 up.
The Wildcats almost equalized a minute before halftime, when a defensive ricochet deflected onto the inside of the Waco post, but the goalkeeper regained his composure to take the ball firmly into his grasp at the second attempt.
The early second half momentum belonged to Waco.
Twelve minutes in, Waco almost made it 3-1 as first a save from Cabrera from point-blank range, and then a defensive block on the line denied them extending their lead.
Jeffrey Reyes then took down a clearance from a corner and lashed a shot just wide of the right post on the half-volley from 25 yards out.
Adrian Rodriguez proved to be the Wildcats' main creative force and, despite a lovely run and turn passed a defender from deep on the right, his shot was easily saved by the Waco goalkeeper with 23 minutes remaining in the match.
Then, with eight minutes to go, Tim Klauser floated in a free kick that looked to be dipping inside the right post, until the Waco goalkeeper beat the ball out to safety for a Palestine corner.
With five minutes left, Diaz stepped up to claim his hat-trick goal, latching onto a ball over the defense and passing it coolly into the bottom left corner of the goal to put Waco 3-1 up, and finish the game as a contest.
Thursday's soccer story should have credited Adrian Rodriguez with one of the Wildcats' two goals in their 2-1 win over Mexia.
Local Sports
H.S. Soccer Playoffs: Diaz hat-trick leads Waco over Palestine
- Local Sports
H.S. Football: Class 1A District 6 Full District Honors
Most Valuable Player
• Tamarcus Sheppard: Italy
Offensive Most Valuable Player
• Keshawn Jackson: Cayuga
Defensive Most Valuable Player
• Zain Byers: Italy
Newcomer of the Year
• Wayne Arellano: Itasca
Coach of the Year
• Charles Tindol and Staff:Italy -
H.S. Basketball: Westwood drops a close game to the No. 10 San Augustine Wolves on Thursday night, 63-54
On Thursday night, the Westwood Panthers' boys basketball team took on the No. 10 team in Class 1A DI and fought hard.
Although the Panthers lost to San Augustine 63-54, there was much improvement from the game at home against Oakwood Tuesday.
H.S. Basketball: Cayuga Ladycats split Thursday's games in the Frankston Tournament
The Ladycats played in two games in the first day of action in the Frankston basketball tournament on Thursday.
In the first matchup, the Ladycats fell for the second time on the season to LaPoynor, 42-32.
H.S. Basketball: The Lady Mustangs of Slocum improve their season record as they beat Frankston on Tuesday night
The Slocum Lady Mustangs squared off against Division 2A Frankston Indians at Slocum HS on Tuesday night and came away with a victory, winning 64-49.
Slocum played their best basketball of the season in the first quarter, taking an 18-5 lead before Frankston could turn up their defense. -
H.S. Basketball: The Lady Panthers push past Athens in a 44-39 victory on Tuesday night
The Westwood Lady Panthers improve on the season as they came away with a 44-39 win against Athens on Tuesday night.
H.S. Basketball: Oakwood's Damiyne Durham scores 34 points to lead them to a victory against Westwood
In a battle of two Dogwood Circle teams, Oakwood prevailed as the better Panther team for the night. Lead scorer and Baylor commit Damiyne Durham led the way for the Oakwood Panthers on Tuesday night in the varsity boys game against the Westwood Panthers in a 91-64 affair.
H.S. Basketball: Cayuga Ladycats move on to 3-1 for the season after beating Buffalo 58-35
Madison Spears led the Ladycats in a 58-35 victory against Buffalo on Tuesday night in Cayuga. Spears' 33 points led the Ladycats, but she didn't do it on her own. Ally Jenkins finished the night with nine points also and Cayuga's defense held strong throughout the night especially in the third quarter.
Three named to the Texas Girls Coaches Association All-State Volleyball Team for 2013.
Three Dogwood Circle volleyball players have been named to the Texas Girls Coaches Association All-State Volleyball Team for 2013.
19-2A All-District Volleyball team named
The Dogwood Circle's Westwood and Elkhart volleyball teams dominated the 19-2A district selections for All-District this year.
UIL realignment includes addition of another class
The state of Texas is making big changes to its UIL classification system, adding another conference to list and eliminating (or renaming) the six-man football division as Class 1A.
- More Local Sports Headlines
H.S. Football: Class 1A District 6 Full District Honors


text:
Hi fellow Conceptart dot orgers,
My name is George Evangelista and I'm a freelance artist with a passion for illustration, character and creature design.
I've been absent here for a while so not sure if I have uploaded some of these before. At the moment I have a few WIP to show but I will update it current sketches soon.
Looking forward to seeing all awesome stuff here and to really get inspired from all you guys. I'm excited to come back here again and looking forward to updating some more.


text:
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- Walgreens expanding scope of retail pharmacy experience and services heading into fiscal 2014
- Walgreens and Express Scripts offer Smart90 Walgreens — a 90-day fill at retail — to improve adherence
- Rite Aid posts third consecutive quarterly profit as company expands Wellness+
- Reports: ESI may start 'price war' over new hepatitis C drugs
GARDEN CITY, N.Y. — The National Association of Professional Women has named former Express Scripts senior director of pharmacy practice Karen Wooten as its VIP Woman of the Year, the group said.
The NAPW said Wooten had been recognized for "outstanding leadership and commitment within her profession." Wooten, who comes from a family of healthcare professionals, began her career almost 30 years ago at Health Management Services, later moving to Medco, which eventually merged into Express Scripts.
"This role allowed me the ability to interact with all levels of leadership and front-line staff," Wooten said. "I influenced and supported the organization to assure and maintain compliance to regulations and standards of practice."


text:
on 05-12-2010 08:35 AM
Everytime I load up Gran Turismo 5 I get "a connection to server could not be established" message. All other games I have will connect to online gaming as will all the other internet-reliant services on the PS3.
So far I have re-installed the game twice, including the 1.02 patch but still without success.
Anyone else encountered this problem and how was it solved?
on 05-12-2010 01:35 PM
on 05-12-2010 10:13 PM
on 06-12-2010 11:49 AM
on 08-12-2010 09:03 AM
Are any of the Sony techs reading these threads? Even after 1.03 and F/W 3.55, I still can't get GT5 to connect where all my other games do.
on 21-12-2010 02:50 PM
solution found at http://www.gtplanet.net/forum/showthread.php?t=144
I manually configured dns to use my isp's dns as primary and router as secondary, and it worked!
on 14-01-2011 12:38 PM
Ended up doing the same thing after running the PS3 through a packet sniffer on my PC. GT5 couldn't resolve the DNS (unlike every other friggen game I've got).
Here, you can post questions regarding any technical problem you may be
Before using this section, be sure to check out our
Technical Solutions board and follow the instructions there to see if your
problem has already been solved.
To use this board, simply post your question and wait for it to be answered. Your question may be given
an 'Accepted Solution' – this is an answer which has been accepted as the best solution to your problem.
Website ©2013 Sony Computer Entertainment Europe
All content, game titles, trade names and/or trade dress, trademarks, artwork and associated imagery are trademarks and/or copyright material of their respective owners. All rights reserved. [more info]


text:
6:00 | Father Brown |
7:00 | ABC News |
7:31 | The Paradise |
8:32 | Midsomer Murders |
10:02 | Call The Midwife |
Episode 1, Friday 6 May 2011
Welcome back to another season of tantalising teases as Claudia, Adrian and Gordon try to identify more mysterious objects. The wildly varied and imaginative suggestions from the streets included a leather working tool, flint cutter, nutcracker, toenail splitter or most disturbingly "an ancient medieval device used to dismember sheep's..."
In the hands of the panel, the implement was given a thorough examination by Adrian who commented on its industrial look and suggested that it was not so much for cutting as splitting.
After some discussion and further examination Adrian concluded it was used in food processing, Claudia maintained it was for working leather and Gordon claimed it was an oversized cigar trimmer.
How close did they come?


text:
Browse our mobile site for the best experience on your device.
Indy's Only Real Classic Rock
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Richard Marx
Richard Marx
Rush Street
Original Release Date: October 28, 1991
Track Listing
1. Playing With Fire
2. Love Unemotional
3. Keep Coming Back
4. Take This Heart
5. Hazard
6. Hands in Your Pocket
7. Calling You
8. Superstar
9. Streets of Pain
10. I Get No Sleep
11. Big Boy Now
12. Chains Around My Heart
13. Your World
Billy Joel: Piano
Cheryl Lynn: Vocals (Background)
Luther Vandross: Vocals (Background)
Brian Jackson: Design
Bill Champlin: Organ (Hammond)
Fee Waybill: Vocals (Background), Producer
Brad Aldredge: Assistant Engineer
Bryant Arnett: Assistant Engineer
Michael Baird: Drums
Ray Blair: Engineer
Terry Bozzio: Drums
Kim Bullard: Keyboards
Rich Caughron: Assistant Engineer
Tamara Champlin: Vocals (Background)
Jon Clarke: Drum Programming
Peter Doell: Engineer
Bill Drescher: Engineer, Mixing
Michael Egizi: Keyboards, Programming, Vocals (Background)
Bruce Gaitsch: Guitar (Acoustic), Guitar, Arranger
Janet Gardner: Vocals (Background)
Steve George: Vocals (Background)
Lolly Grodner: Assistant Engineer
Steve Grove: Saxophone
Mick Guzauski: Mixing
Mark Hagen: Assistant Engineer
Jerry Hey: Horn Arrangements
Leslie Ann Jones: Assistant Engineer
Michael Landau: Guitar (Acoustic), Guitar, Arranger, Guitar (Electric)
Steve Lukather: Guitar, Arranger
Brian Malouf: Mixing
Richard Marx: Piano, Arranger, Keyboards, Vocals (Background), Producer, Fender Rhodes
Pat McDougal: Assistant Engineer
Marcus Miller: Bass
Cindy Mizelle: Vocals (Background)
Jonathan Moffett: Drums
Richard Page: Vocals (Background)
Jeff Porcaro: Arranger, Drums
Greg Phillinganes: ?
Kevin Reeves: Assistant Engineer
Mark Stebbeds: Assistant Engineer
Wally Traugott: Mastering
Chris Trujillo: Percussion
Matt Westfield: Vocals (Background)
Dave Wittman: Engineer
John "Juke" Logan: Harmonica
Tommy Lee: Drums
Michael Douglas: Assistant Engineer
Susanne Edgren: Production Coordination
Tom Nellen: Assistant Engineer
Randy Wine: Assistant Engineer
Dalbello: Vocals (Background)
Lee Thornberg: Trombone, Trumpet
Paul Warren: Vocals (Background)
Larry Vigon: Art Direction, Design
Randy Jackson: Bass
Jesse Kanner: Assistant Engineer
Rick Norman: Assistant Engineer
Nels Israelson: Photography
Brandy Rosenberg: Vocals (Background)


text:
- August 11, 2010
- 9:26 a.m.
- Suggest removal
- Reply to this post
asawyerjr writes:
Mr. Cohen and other can hide behind race neutrality. But hiding and posturing about some higher dream than the reality does not chance the issues or make them go away. Race is Memphis. Race is Shelby County. Race is Tennessee. Race is the United States of America. We cannot forget our past, or our present. Things are not right between the two races in the United States. If we continue to hide in caves with our heads in the sand, we will never resolve this ultimate issue of life in America.
Want to participate in the conversation? Become a subscriber today. Subscribers can read and comment on any story, anytime. Non-subscribers will only be able to view comments on select stories.


text:
Top Apps
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Showing page 1 of 6.
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Icinga Open Source Monitoring
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text:
Home & Garden
A legacy of inspired uncorkings.
The new Legacy Opener removes corks swiftly and easily and looks great doing it. The handsome bronze Legacy is a cast replica of a classic antique, replete with decorative grapevine adornments. It uncorks with just a pull of the handle and mounts elegantly to your bar or on our decorative table stand. Opens all sizes and types of wine bottles including flange tops.$59.95 - $79.95 -
Home & Garden
Get ready for the holidays with holiday decor, or create an outdoor oasis with garden and patio furniture and fashions that are fun and functional.
Cheers to this glassware for pulling double duty!
Its unique handblown, double-wall design provides extra insulation, so your wine stays at its proper serving temperature regardless of how long you've held the glass. It also creates a "suspended" visual effect for a compelling presentation. Use for hot tea and coffee, too! Lead free Crystal. Dishwasher safe.$19.953.0/5 (1) -
Home & Garden
Get ready for the holidays with holiday decor, or create an outdoor oasis with garden and patio furniture and fashions that are fun and functional.
Brandy Warmer 4-Piece Gift Set
Rekindle your love for Brandy.
Experience a mouth-watering melange of aromas and flavors only a perfectly positioned candle flame can release. All the elements (except the Brandy) are here: mouth-blow over-sized lead-free snifter, chrome stand, votive candle, and glass votive holder.
Snifter is dishwasher safe, chrome stand should be wiped clean with a damp cloth.
Size: Snifter - 6"H, 25 oz.; Stand - 7"H$29.95 -
The new collection is versatile, beautifully crafted and exceptionally well priced.
You can use these sturdy pieces alone or group them together to create a customized system. Because of their simple, clean lines and built-in versatility, you can enjoy them in a variety of settings including the kitchen, pantry, family room, or den. All pieces assemble easily and come with all necessary hardware.
14-Shelf Wine Rack. Holds 126 bottles, (each shelf holds 9 btl.). Connect two or more racks side by side to create expanded storage.$229.95 - $249.95 -
Ambassador Whiskey Decanter
Top ranking design for genteel serving.
Ideal for carrying on the rich tradition of Whiskey drinking and enjoyment. Substantial yet balanced with thick European glass, mouth-blown. Topped with a solid glass stopper.
Lead-free. Made in Europe.
Size: 9-3/4"H, 35 oz.$39.95 -
Riedel Vinum Single Malt Scotch Glasses (Set of 2)
Riedel Vinum Single Malt Scotch Glasses were developed with the help of distillers and experts to bring out the best qualities in fine Malt Whiskys. The resulting whisky glass is sized and shaped with a flared rim to bring out the complex, multi-layered aromas of the finest whiskies. It's the perfect sized glass allowing you to swirl the spirit and gather the aromas around the rim.
Riedel Vinum Wine Glasses make every drop of wine taste its best. Riedel revolutionized glassware by customizing the shape of wine glasses to a particular type of wine. Each wine glass is fine-tuned to direct the flow of the wine onto parts of the palate that will best express the flavors and aromas of a specific wine varietal. The fine crystal offers superb clarity so you can experience the wine's color and texture. Moreover, all machine made Vinum stems are completely dishwasher safe. Made of over 24% leaded crystal.
Recommended for: Single Malt Whisky, Malt Whisky, Whisky/Whiskey
Size: 4-1/2"H, 7 oz.
Riedel Model # 6416/80$49.95 -
Wine Glass Holder Necklace (Set of 2)
Keep your hands free at parties by keeping your wine close at heart! This clever little clip with adjustable strap holds a regular-size stemmed glass to your chest, giving you the freedom to snack and socialize as you sip!
Size: Strap - 36"L$24.954.3/5 (11) -
Enjoy every wine at its peak of drinking pleasure. A scientific breakthrough product with the classic brushed steel handle!
Clef du Vin lets you assess the precise ageability of any wine. When dipped into wine, a patented metal alloy located on the tip of Clef du Vin replicates the key aspects of the natural aging process. You'll know the ideal moment to enjoy every wine at its peak. Developed and tested over 10 years by one of France's leading scientists and wine industry consultants and European Champion Sommelier, Clef du Vin has received wide acclaim throughout Europe and Asia and is available in The U.S. now, for the first time, only from Wine Enthusiast. (Pocket Version)- Lets you see the future of any wine
- Determines the ideal length of time to cellar wines
- Unique patented device, widely acclaimed in Europe and Asia
- Folds up pocket size with a handy carry chain
- Goes with you to restaurants, wine shops, wine tastings and traveling.
- An essential gift for any wine lover
- Lets you manage your wine cellar like you have a crystal ball.
Brushed Steel$99.955.0/5 (2) -
EuroCave, maker of the world's finest wine cellar, now brings you the pinnacle of wine preservation!
Chills and preserves opened wine up to 10 days! Just place an uncorked bottle inside, close the door, slide EuroCave's patented vacuum cylinder over the bottle neck, and set the desired temperature. No stoppers, pumps, or gases required. The EuroCave SoWine Home Wine Bar is all you need!- Exclusive vacuum technology chills and preserves wine for up to 10 days
- 2 independent compartments* can preserve red and white wines at their respective serving temperatures for by-the-glass enjoyment
-- A full bottle of red wine is brought from cellar temperature (55 degrees F) to ideal serving temperature (61-65 degrees F) in approximately 3 hours
-- A full bottle white wine is brought from cellar temperature (55 degrees F) to ideal serving temperature (46-50 degrees F) in approximately 1 and a half hours- Self-setting controls with indicator lights confirm vacuum seal and temperature
- Can also chill unopened wine bottles**
- Contemporary design complements any kitchen or entertainment area
Size: 19-1/2"H (with cylinders up) / 17"H (with cylinders down) x 9-3/4"W x 9-3/4"D
*The compartments can fit most 750mL size bottles up to 12-1/2" high. It can not accommodate 1.5L bottles and larger, as well as 375mL Split bottles. Not recommended for use with Sparkling Wines including Champagne.
**When chilling unopened wine, do not slide vacuum cylinder over bottleneck. Just close the door(s) and set the desired serving temperature for red or white.$395.005.0/5 (2) -
Fireplace Screen
Fireplace screens are the focal point of any room and the beautiful colors will enhance the look of the area. Both functional and decorative these unique decorative screens will keep your fireplace out of sight when not in use. This piece is handcrafted from original artwork by Virginia artist Nancy Cane. Item is already assembled in box and ready to be put in front of the fireplace . Dimensions: 31H x 44W x 3/8L inched.$62.745.0/5 (1) -
Store and serve from 2 separate zones!
The Wine Enthusiast Silent 18 Bottle* 2-Temp Wine Refrigerator offers a stylish reflective smoked-glass door finish that has 2 zones. The top zone has an adjustable temperature range of 54-64 degrees F providing storing conditions for reds and whites. While the bottom zone has an adjustable temperature range of 46-64 degrees F providing ideal storing conditions for reds and white, and optimum serving conditions for most whites. Increase the convenience of temperature control with an exterior digital touchscreen. This silent cooling system has no moving parts and is CFC-free, meaning that you get silent, long-lasting, and environmentally safe refrigeration for your collection.
Wine Enthusiast 18-bottle* 2-Temp wine cooler is built solid and reliable. A quality unit to save, store or serve your wines in ideal conditions, it features:- 18 bottle capacity*
- 2 zone storage for both reds & whites
- Bottom zone has optimum serving conditions for most whites
- Ultra-quiet thermoelectric cooling
- Exterior digital touchscreen with display
- Eco-friendly; releases no gaseous refrigerants; energy efficient
- Thermopane glass door with reflective smoked-glass finish
- 4 pull-out chrome shelves
- Interior LED lighting
- Free Standing Only**
Size: 25-1/2"H x 14"W x 19-3/4"D
*Note: Shelving is meant to hold standard 750 mL size bottles, using larger Pinot Noir/Rhone size bottles may limit the capacity. If you would like to store larger bottles you can easily remove any of the shelves. This will also prevent scraping the labels on the larger bottles.
**Applications: This model is not meant to be built-in to cabinetry, recessed or put underneath a counter. Additionally this model is not meant to be used in an enclosed area. While the back of the unit does produce a minimal amount of heat, it still needs to vent to an open area.$249.955.0/5 (1) -
Wine Cork Serving Tray Kit
Pop those wine corks...and create a wine cork serving tray.
Our wine cork kits are one of our most popular products, since half the fun is in the making! The serving tray in maple will make your guests impressed with not just your food but the tray too. Just arrange the wine corks on the tray and slide the clear Plexiglas cover over them. Everything stays in place without a messy gluing process. Includes oak tray, Plexiglas cover, and instructions. You supply the corks. Gift Boxed.
Size: 17"L x 13"W
Approximately 108 wine corks are required to complete wine cork tray.
Note: Wine corks vary in size.$39.954.8/5 (4) -
Jean Dubost Laguiole 6-Piece Steak Knives
In a word: sharp. Laguiole takes inspiration from a 19th Century shepherd's tool and creates a handsome, streamlined utensil. Crafted from polished stainless steel, each steak knife features a hard, slightly curved handle casing. The "bee" symbol on each 9" piece assures legendary Laguoile quality. Set of 6. Dishwasher safe. Comes in a beechwood gift box.
This is crafted in 18/8 Stainless Steel.$69.954.5/5 (4)more colors -
Be space-conscious and planet-conscious!
Our super-popular modular crate just got better--it got green! Made from 100% recycled materials, the STORViNO Nero Wine Storage Container, now in black, has all the same space-saving benefits of the original, holding up to 6 wine bottles* compactly. Solid polyethylene construction with convenient hand slots make it easy to transport and safe to stack. Sold individually.
Size: 10-1/4"H x 11-3/4"W x 8"D
*This wine rack will accommodate bottles that have a diameter of 3-1/4" or less.$19.954.0/5 (1) -
Click here to see info on our 10-year replacement warranty
The world's most break-resistant wine glasses!
Super-strong, lightweight magnesium is fused with brilliant European crystal to form the most durable wine glasses in the world. Fusion stemware withstands the wear and tear of everyday use and never dulls or clouds. Varietal-specific, Fusion stems are scientifically shaped to enhance the best qualities of your wine. Lead-free and machine-made. Dishwasher safe. Set of 4.
Choose a style from the drop-down box above.$49.95 - $89.954.0/5 (1) -
The perfect stemless wine glasses for U!
Stemless wine glasses are all the rage and these beautiful chardonnay stemless wine glasses are just what you're looking for. Shaped to enhance your wines' flavors, they're made of fine quality lead-free crystal and because they're stemless, they fit easily in your cabinets and dishwasher. A perfect choice for casual entertaining and everyday enjoyment.
Choose a style with or without monogram from the drop-down box above.$12.95 - $29.954.0/5 (1) -
Stackable Racks.
Made of solid unfinished pine. Scalloped crossbars fit snugly into the endpieces. A snap to assemble. Available in 18- and 26-bottle widths.
$44.95 - $54.954.0/5 (1) -
Master your wine senses!
This comprehensive kit will help you to identify wine tastes and aromas like a true connoisseur. You'll develop an extensive wine vocabulary and be well educated when selecting wines at restaurants and stores. You'll also impress your friends with how much you know! Contents below come neatly organized in a solid pine gift box with leather handles and brass latch. Includes detailed instruction booklet.
Set Includes:
- 9 vials of the most common essences (tastes) found in wine, including fruity and oak
- 9 essence coasters for identifying specific wine tastes
- 2 tasting glasses for sampling wine essences
- 36 vials of the most common aromas found in wine, including dark chocolate and apple
- 36 aroma cards describing scents and the specific wines in which they are present
$199.953.0/5 (2) -
Fusion Classic Port Wine Glasses (Set of 2)
The world's most break-resistant wine glasses!
Super-strong, lightweight magnesium is fused with European crystal to form the most durable Port glasses in the world. Fusion Port Glasses are also scientifically shaped to enhance the taste and bouquet of your favorite libation. Lead-free and dishwasher-safe. Machine-made in Europe.
Size: 6-1/4"H, 7 oz.
Fusion 10-Year Limited Warranty
In the unlikely event your Wine Enthusiast Fusion Glass breaks, we'll replace it FREE, even up to 10 years after purchase!$29.95 -
11 in. Tillandsia Pick 36-Pack
Allstate Floral Craft is a leading importer of artificial silk flowers handwrapped flowers flowering bushes foliage and plants.Also featured in our vast inventory are floral containers fruits, vegetables cactus and ribbon.We offer seasonal items with a major emphasis on Christmas trees wreaths garlands swags; along with themed trees decorations ornaments berries and accessories.Our inventory consists of over 10 000 items with various programs and price points to fit your wholesale and retail needs.For quality price and services Allstate Floral Craft offers it all. Artificial. Sold in a set of 18 Green Tillandsia Picks. Cubic Ft: 4.23". Size: 11".$64.15 -
Uniquely designed so your hand warms the spirits as you sip through the stem, enhancing the flavor of ports and liqueurs. Crafted of durable hand-blown lead free glass. Hand wash. 3"H, 4 oz$39.95
Wine Enthusiast Silent 12 Bottle Wine Refrigerator (Stainless Steel Trim Door)
The Wine Enthusiast Silent 12 Bottle* Countertop Wine Refrigerator comes in black body with a stainless steel trimmed glass door with chrome handle. This stylish refrigerator keeps your best bottles cool without making a peep. The secret is Peltier's thermoelectric cooling technology. This cooling system has no moving parts and is CFC-free, meaning that you get silent, long-lasting, and environmentally safe refrigeration for your collection.
Wine Enthusiast 12 bottle* wine cooler is built solid and reliable. A quality unit to save or store your wines in ideal conditions, it features:
*12 bottle* capacity
*Proper storage temperature for your wine
*Ultra-quiet thermoelectric cooling
*Digital temperature display
*Easy push button controls
*Eco-friendly; releases no gaseous refrigerants; energy efficient
*Black body with a stainless steel trimmed glass door and chrome handle
*Thermopane glass door
*3 chrome pull-out shelves
*Interior light
*Free Standing Only
Size: 15"H x 15-3/4"W x 19-3/4"D
*Note: Shelving is meant to hold standard 750 mL size bottles, using larger Pinot Noir/Rhone size bottles may limit the capacity. If you would like to store larger bottles you can easily remove any of the shelves. This will also prevent scraping the labels on the larger bottles.$149.95 -
Stem Shine.
Never worry about streaks or off odors on your fine glassware again. This innovative glassware liquid cleaner will revolutionize the way you clean your glasses. Exclusive Stem Shine is specific for hand-washing fine glasses. It doesn't just clean your glassware, it purifies them.
The cleaning agents go into the pores of fine crystal and other glassware and removes every trace of soil and contaminants. Stem shine then evaporates quickly preventing streaks and completely removing odors that could compete with your fine wine's bouquet$29.95 - $44.95 -
Fusion Infinity Glassware
Toast with confidence! Sleeker shapes, wider bowls, taller stems - the latest trend in wine stemware - take Fusion elegance and strength to the next level. Brilliant European crystal is fused with super-strong magnesium to form the world's most break-resistant glasses, as lightweight and graceful as they are durable. Science meets sophistication, and the result is shatterproof. Shaped to enhance the best qualities of your wine. Machine made lead-free crystal; never clouds or dulls. Dishwasher safe.$69.95 - $139.90 -
Laguiole Flatware Set: French craftsmanship at it's very best
The trademark "bee" on every piece of flatware assures you that this set is crafted in France according to a centuries-old tradition. Sleek shape, impressive heft and gleaming stainless steel construction help to make it appropriate for any table. Marbleized ABS handles are reminiscent of ivory and ebony. 25-piece set includes storage chest and 6 each: dinner fork, knife, soup spoon and French teaspoon. Choose pearlized ivory or black. Dishwasher-safe.
$179.95 -
96-Bottle Antiqued Steel Wine Jail
"Lockup" never looked more inviting.
Protect your wine behind the steel scrollwork of this handsome storage jail, antiqued with a bronze finish to enhance any room. Includes jailer's padlock and key.
Holds 96 bottles. Easy assembly.
Size: 71-1/2"H x 25"W x 16-1/4"D$499.00 -
12 Bottle Cube-Stack Wine Rack (Walnut Stain)
Stack racks high and save on space!
One level, two levels, three. . . . Easily adjust the size and configuration of your wine collection with this 12-bottle, stackable hardwood rack! Designed to fit securely one on top of the other for space-saving storage. Strong, weighty hardwood allows you to stack from floor to ceiling safely.
No hardware required to stack, but should be secured to the wall if 3 or more are stacked high.
Walnut stained Mahogany wood.
Size: 15-1/2"H x 18-7/8"W x 10-9/16"D$64.95 -
Wine Enthusiast Silent 28 Bottle Wine Refrigerator
The Wine Enthusiast Silent 28 Bottle Wine Refrigerator offers classic, complementary styling for the home with a stainless steel-trim door. It makes adjusting the temperature easy with push-button controls on the door and it protects the taste of reds and whites with virtually silent cooling technology.$299.95 -
Tapestry Flowers Fireplace
This is a lithograph of original artwork that has been reproduced laminated onto MDF board and then cut out hinged and hand finished to make a decorative fireplace that is used whenever the hearth is not is use. Features:. Fireplace screen. Constructed of lithograph laminated on MDF. Three panels enable you to fold it to vary the width and will cover almost all sizes and types of fireplaces. Fireplace screens are the focal point of any room. Beautiful colors of fireplace will enhance the look of room. Handcrafted from original artwork by English muralist Julie Perren. Can folds up when not in use. Specifications:. Assembly required. Overall dimensions: 31H x 44W x 0.5D inches.$62.60 -
Trilogy Wine Cellar
Three separate storage compartments in one handsome furniture cabinet allow you to organize your wine 3 different ways: Enjoy the extra capacity of three 16-bottle compartments!
A master touchscreen control panel lets you adjust the temp (54-66 degrees Fahrenheit), power on/off each storage area. All compartments in the mahogany-stained wood cabinet feature: Virtually silent thermoelectric cooling technology.
Thermopane glass door w/ metal handle & key lock. 3 pull-out chrome shelves w/ wood trim. 3 interior blue LED lights. ETL approved.
Size: 75-3/4"H x 20-3/4"W x 21"D
Select Right-Hand or Left-Hand Hinged Door.$1,295.00 -
Siena Wine Credenza
Leave it to Italy's finest craftsmen to make you fall in love with furniture.
This premium-quality wine credenza is hand-made from tulip & walnut hardwoods, then hand-stained in rich walnut with patina applications. Accented with solid brass hardware & features. . . 3 rolling wood shelves that hold 9 wine bottles each, including larger bottles. 2 spacious storage areas with sliding pocket glass doors, adjustable shelves, & room for a 9-glass Stemware Rack.
Includes a deep rolling top drawer for even more storage.
Size: 36"H x 75"W x 25"D
Note: This item does not come with a refrigerator.$1,895.00 -
Wine B'Gone Stain Remover Spray (16 oz.)
Advanced formula, fast-acting!
Even better than the original Wine B' Gone customers hail as "the best on the market. " Advanced surface-active agents remove wine stains faster and safer than ever from clothing, upholstery, carpets, sinks, countertops. . . just about anything.
Removes Wine Stains and So Much More In addition to red and white wine stains, Wine B' Gone Ultra removes many other tough stains.
Size: 16 oz. spray bottle$19.95 -
Nuance Wine Finer Aerator
Exclusive Offer: FREE Carry Case!
Compliments of Wine Enthusiast.
When you purchase the Nuance Wine Finer, you'llreceive the Carry Case, a $4.95 value, for FREE!
Four functions, one amazing invention. Serving wine gets a whole lot simpler with the Nuance Wine Finer Aerator. Danish designers combine an aerator, filter, non-spill pourer, and stopper into one do-it-all instrument the size of a fountain pen. Just insert the Nuance Wine Finer Aerator into your bottle and pour. Wine flows through 32 aeration vents while an inner stainless steel screen filters out sediments and cork. Stand your bottle upright and the pourer catches any drips. Top your Wine Finer with the stopper to enjoy a glass later. Four functions, one amazing invention. Body made of solid silicon; pourer and stopper tip made of stainless steel. Dishwasher Safe.
Size: 7"H$29.95 -
Black Tie Grids - High Style, Low Cost
The clean design and economical cost make these racks ideal. Holding up to 150 bottles, the sleek black steel grids can be installed side-by-side (mounting brackets and hardware are included) or double deep (optional metal braces available).
Measures 66" H x 30" W x 8" D.$99.95 -
Weekend Wine Bag on Wheels
Toasting on trips is easy!
Glides up to 6 bottles of wine or champagne to a picnic, tasting or outdoor concert. Inside and outside pockets. Insulated black nylon with plastic wheels and pull handle. Features Wine Enthusiast Lord Winston logo on front.
Detachable shoulder strap. Ice pack included.
Size: 14"H x 11"W x 9"D;
Handle extends to 34-3/4"H$89.95 -
Organize your wine!
Cut to fit over standard- and large-size bottlenecks. Made of paper.
Select color.$14.95 -
Siena Mezzo Wine Credenza
Let impassioned Italian design steal your heart.
Leave it to Italy's finest craftsmen to make you fall in love with furniture. This premium-quality wine credenza is hand-made from tulip & walnut hardwoods, then hand-stained in rich walnut with patina applications.
Accented with solid brass hardware & features: 2 spacious storage areas each with sliding pocket glass doors, 2 adjustable shelves, & room for a 9-glass Stemware Rack (sold separately). Either area will also fit our 28-Bottle Wine Refrigerator. (Not included)
Size: 36"H X 52"W X 25"D
Note: This item does not come with a refrigerator.$1,495.00 -
Microfiber Wine Glass Towels (Blue - Set of 4)
Say bye to lingering lint.
A smooth, taut, and textured poly-blend fabric wipes away water without leaving lint behind. Dries and buffs your crystal to a dazzling finish!
Machine washable.
Size: 15" x 15"$14.95 -
Rabbit Corkscrew 6 Piece Wine Kit (Black)
Reproduce flawless openings with multiple tools. The ultimate all-in-one wine corkscrew set for all your wine service needs. You get everything you need for wine bottle opening and service in this convenient and affordable Rabbit Corkscrew set from Metrokane. The 6-piece corkscrew kit includes the world-famous Rabbit Corkscrew, foil cutter, drip-stop drip ring, worm, wine/champagne sealer, and wax remover. The Rabbit Corkscrew was redesigned with an all new precision metal gear mechanism for even smoother and more reliable wine bottle opening.
This corkscrew is synthetic cork friendly.$64.95 -
SoHo Bar Glasses (Set of 2)
Bold yet dignified, like the finest spirits.
From the moment you feel its weight in your hand, you realize this is no ordinary glass. The base alone is 1-1/2" thick, a solid foundation for substantive walls with a cross-pattern cut exuding character. Plenty room for ice.
Made in Europe.
Size: 4"H, 12 oz.$49.95 -
Dog Fireplace Screen
Exquisite detail and rich natural color inspired by the European countryside make this dog fireplace screen a distinctive way to add warmth and color to your home. Update the look of your fireplace or use it as a unique accent in any desired area. It is made of sturdy 3/8 thick wood composite and then superbly hand-finished. Dimensions: 42W x 31H inches.$62.95 -
Fusion Triumph Wine Glasses
An Unprecedented Fusion of Opulence, Strength & Value.
Fusion, the World's Most Break-Resistant Stemware, marks a groundbreaking achievement with its Triumph line.- Oversized Bowls & Bases facilitate swirling and aerating and reveal full bouquet
- Tulip-Shaped Rims direct the flow of wine to key taste receptors on the tongue
- Pulled Stems enhance the elegance and durability of one fluid piece of glass
- Mouth-Blown Artistry achieves just the right shape and balance to bring out the best qualities in wine
- Lead-Free Composition ensures every toast is to your health
Size: 10-1/2"H, 40 oz.
Fusion 10-Year Limited Warranty
In the unlikely event your Wine Enthusiast Fusion Glass breaks, we'll replace it FREE, even up to 10 years after purchase!
Select item.$69.95 -
Silent 32 Bottle Dual Zone Touchscreen Wine Refrigerator
Store & serve from 2 separate zones! This thermoelectric, energy-efficient, CFC-free wine cooler. . . Protects the taste of reds & whites w/ updated, virtually silent cooling technology in 2 zones. Increases the convenience of temperature control w/ an exterior digital touchscreen.
ETL approved. Reflective Thermopane smoked-glass door w/ recessed handle & stainless trim. 32-bottle capacity: Two 16-bottle zones. 5 pull-out chrome shelves. Interior LED lighting.
Size: 33-1/2"H w/ hinge x 15-3/4"W x 20-3/16"D$349.00 -
12 Bottle X Cube-Stack Wine Rack (Walnut Stain)
Stack racks high and save on space!
One level, two levels, three. . . . Easily adjust the size and configuration of your wine collection with this 12-bottle, stackable hardwood rack! Designed to fit securely one on top of the other for space-saving storage. Strong, weighty hardwood allows you to stack from floor to ceiling safely.
Stand alone or stack with the 12-Bottle Cube Rack and Wine Glass Rack for flexible storage.
No hardware required to stack, but should be secured to the wall if 3 or more are stacked high.
Walnut stained Mahogany wood.$64.95 -
Steady-Temp Double Wall Beer Glasses (Set of 2)
Keep cool drinks cool!
Cheers to this glassware for pulling double duty! Its unique hand-blown, double-wall design provides extra insulation, so your beer stays at its proper serving temperature regardless of how long you've held the glass. It also creates a "suspended" visual effect for a compelling presentation.
Stable, durable design made of lead-free crystal.
Dishwasher safe.
Size: 6"H, 16 oz.$19.95 -
SPIEGELAU Vino Grande Decanter
Wonderfully elegant, generously proportioned and surprisingly affordable, these decanters provide maximum breathing space for your wines. The beautifully tapered long neck allows for graceful lifting and pouring.
8" H, 36 oz. For decanting a standard wine bottle
Proposition 65 Warning for California Residents: Use of this product will expose you to lead, a chemical known to the State of California to cause birth defects or other reproductive harm. You may also obtain a list of each brand of leaded crystal and tableware for which this warning is given..$63.95 -
Easy access to perfectly stored wine has never been more stylish! The new exterior touch screen and reflective smoked-glass door of our 28-Bottle Touch screen Wine Refrigerator are sights to behold on any countertop. Treat your reds, your whites, and yourself to the new generation in wine storage!
- Ultra-quiet thermoelectric cooling maintains ideal wine storing temperature
- Pull-out chrome shelves
- Interior LED lights highlight bottles
- ETL approved
29-1/4"H x 18-1/4"W x 21-1/4"D$329.00


text:
Like Clark Kent stepping into a phone booth and emerging as Superman, Noble Creek Community Park shifted to its superhero status during last weekend's fires in the San Gorgonio Pass.
The park in its mild-mannered mode serves as a sports complex and community center with, quite uniquely, a 24-space RV area that is in demand during special events and tournaments.
The park was especially equipped during the past half-dozen years to have special data and electrical lines, concrete pads that can support heavy fire equipment during inspections and overhead lighting to better serve as a fire camp or an emergency disaster center.
"They call it the Cadillac of fire camps," said Mickey Valdivia, general manager of the Beaumont-Cherry Valley Recreation District.
The park is on Oak Valley Parkway in Beaumont, close to Interstate 10. During the busy 2006 fire season, it was used five times as a fire camp, prompting the district to make the improvements.
Last weekend, a 66-team baseball tournament quickly was moved to Beaumont city and school fields and a Monday night outdoor movie was canceled. The park became an instant city where firefighters were fed and slept in tents pitched on grass fields and fire-fighting strategy was planned.
"We are really proud of the amenities," Valdivia said. "They have shade. They have grass."
Use of the park as a fire camp comes with a price. Valdivia recently signed a contract calling for payments of $3,500 per day.
Jason Strain believes work will begin quickly to determine the mysterious financial status of the beleaguered Valley View Foundation, the nonprofit that began a drive late last year to purchase the historic Hemet Theatre and convert it into a performing arts center.
Supporters of the project estimate that more than $100,000 was donated to the cause, but can't be sure because foundation CEO Sharon Deuber won't say.
Deuber tried to kick Strain and Nick Reed off the board and continue on with her mother, Laura Roach, as the only other officer. She has steadfastly refused to release information about donations and how they were spent.
Strain and Reed maintain that her attempt to remove them from the board was improper.
With advice from Hemet attorney Bruce Wallis and support from donors, they will hold a meeting Monday, June 25, at Inland Chevrolet to reorganize the board. Donors of $500 or more, according to theater supporters, are allowed by bylaws to vote for board members. Deuber is expected to be removed from the board.
"I would imagine with the new board in place, it would be a matter of a day or so to get the records from the bank," Strain wrote. "Then it will be compiling what bills were paid, what transactions took place and totaling assets."
Contact Bob Pratte at 951-763-3452, firstname.lastname@example.com or 3400 Wentworth Drive, Hemet CA 92545. Find Bob's blog at blog.pe.com/bob-pratte, and follow him on Facebook at www.facebook.com/PE.BobPratte and Twitter: @bpratte


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Can't make it to the North Pole? Do the next best thing and come to Cosley Zoo! Enjoy a visit with Santa, make a craft or two and enjoy cookies, punch and coffee. Photos with Santa are available for a small fee. Free Zoo admission! Call 630.665.5534 for more information.
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Publications (7)58.48 Total impact
- Annales d Endocrinologie 05/2008; 69(2):101-2. · 1.02 Impact Factor
- [show abstract] [hide abstract]
ABSTRACT: The function of the plasma membrane calmodulin-dependent calcium ATPase (PMCA) in myocardium is unknown. PMCA is localized in caveolae, 50- to 100-nm membrane invaginations, which also contain receptors for endothelin-1 (ET-1) and various other ligands. PMCA has been suggested to play a role in regulation of caveolar signal transduction. We studied the effects of the hypertrophic agonist ET-1 and increased coronary perfusion pressure on cardiac synthesis of B-type natriuretic peptide (BNP) in transgenic rats overexpressing the human PMCA 4CI in isolated perfused heart preparation. ET-1 infusion for 2 h increased BNP mRNA levels twofold in left ventricles (LV) of nontransgenic rats, whereas no increase was noted in PMCA rat hearts. Similar responses were seen in adrenomedullin and c-fos mRNA levels, and in immunoreactive BNP secretion. Increased mechanical load produced by elevated perfusion pressure induced similar 1.5- to 1.6-fold increases in LV BNP mRNA in both nontransgenic and PMCA rat hearts. These results show that cardiac overexpression of PMCA attenuates ET-1-stimulated early induction of cardiac gene expression, suggesting that PMCA may modulate myocardial growth responses.AJP Regulatory Integrative and Comparative Physiology 10/2001; 281(3):R699-705. · 3.28 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Alternative splicing of Wt1 results in the insertion or omission of the three amino acids KTS between zinc fingers 3 and 4. In vitro experiments suggest distinct molecular functions for + and -KTS isoforms. We have generated mouse strains in which specific isoforms have been removed. Heterozygous mice with a reduction of +KTS levels develop glomerulosclerosis and represent a model for Frasier syndrome. Homozygous mutants of both strains die after birth due to kidney defects. Strikingly, mice lacking +KTS isoforms show a complete XY sex reversal due to a dramatic reduction of Sry expression levels. Our data demonstrate distinct functions for the two splice variants and place the +KTS variants as important regulators for Sry in the sex determination pathway.Cell 09/2001; 106(3):319-29. · 31.96 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: The plasma membrane calmodulin-dependent calcium ATPase (PMCA) is a calcium-extruding enzyme controlling Ca2+ homeostasis in nonexcitable cells. However, its function in the myocardium is unclear because of the presence of the Na+/Ca2+ exchanger. We approached the question of the physiological function of the calcium pump using a transgenic "gain of function" model. Transgenic rat lines carrying the human PMCA 4 cDNA under control of the ventricle-specific myosin light chain-2 promoter were established, and expression in the myocardium was ascertained at the mRNA, protein, and functional levels. In vivo hemodynamic measurements in adult homozygous animals showed no differences in baseline and increased cardiac performance recruited by volume overload compared with controls. No differences between transgenic and control cardiomyocytes were found in patch clamp voltage dependence, activation/inactivation behavior of the L-type Ca2+ current, or fast [Ca2+]i transients (assessed by the Fura-2 method). To test whether the PMCA might be involved in processes other than beat-to-beat regulation of contraction/relaxation, we compared growth processes of neonatal transgenic and control cardiomyocytes. A 1.6- and 2.3-fold higher synthesis rate of total protein was seen in cells from transgenic animals compared with controls on incubation with 2% FCS for 24 hours and 36 hours, respectively. An effect of similar magnitude was observed using 20 micromol/L phenylephrine. A 1.4-fold- and 2.0-fold-higher protein synthesis peak was seen in PMCA-overexpressing cardiomyocytes after stimulation with isoproterenol for 12 hours and 24 hours, respectively. Because pivotal parts of the alpha- and beta-adrenergic signal transduction pathways recently have been localized to caveolae, we tested the hypothesis that the PMCA might alter the amplitude of alpha- and beta-adrenergic growth signals by virtue of its localization in caveolae. Biochemical as well as immunocytochemical studies suggested that the PMCA in large part was colocalized with caveolin 3 in caveolae of cardiomyocytes. These results indicate that the sarcolemmal Ca2+-pump has little relevance for beat-to-beat regulation of contraction/relaxation in adult animals but likely plays a role in regulating myocardial growth, possibly through modulation of caveolar signal transduction.Circulation Research 12/1998; 83(9):877-88. · 11.86 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: To study the physiological function of the plasma membrane calmodulin-dependent calcium ATPase (PMCA) in intact cells, L6 myogenic cell lines stably overexpressing the human PMCA isoform 4CI (= human PMCA isoform 4b) were generated. Several independent L6 clones and controls stably transfected with the empty expression vector were analyzed in detail. The resting cytosolic calcium level in hPMCA4CI-overexpressing muscle cells (measured by the Fura-2 method) was significantly reduced by 20-30% compared with controls. This was shown in a cytosolic window of 1322 single cells (p < 0.01). Furthermore, the differentiation process of these cells was remarkably accelerated compared with control myoblasts and parental nontransfected L6 cells as assessed by multinucleated myotube formation and creatine phosphokinase activity elevation. After 4 and 6 days of differentiation, PMCA-overexpressing L6 cells from four independent clones displayed a 3- and 4-fold higher creatine phosphokinase activity compared with controls (n = 5, p < 0.02). These results may extend the concept of the function of the PMCA from simple prevention of calcium overload to an active involvement in intracellular calcium regulation with potentially important consequences for cellular functions.Journal of Biological Chemistry 11/1996; 271(48):30816-22. · 4.65 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: The functional significance of the isoform diversity of the calmodulin-dependent plasma membrane Ca(2+)-ATPase (PMCA) is largely unknown. To determine whether the mRNA synthesis of different isoforms of the enzyme is regulated in a differentiation-specific manner, we investigated the expression of isoform-specific mRNAs in muscle and neuronal cells during differentiation by reverse transcription PCR. In the rat, the ubiquitous PMCA splicing variants 1b and 4b formed the typical PMCA isoform pattern of L6 myoblasts, the heart-derived cell line H9c2(2-1), two different fibroblast cell lines (FR and NRK-49F), smooth muscle, and endothelial cells. In addition to these two enzymes, novel expression of the splicing variants 1c, 1d, and 4a was induced during myogenic differentiation of L6 and H9c2(2-1) cells. A similar isoform subtype switch could be detected during differentiation of the neuronal PC-12 cells induced by nerve growth factor (NGF). The isoform-specific mRNAs 1c, 1d, and 4a were not expressed in cells other than myocytes and neurons, and therefore may be specific for excitable cells. The mRNA for isoform 1d was heart- and skeletal muscle-specific. To determine whether expression of a differentiation-specific PMCA mRNA pattern is under control of a myogenic determination factor, myogenin was constitutively expressed in rat fibroblasts. These cells converted to multinucleated myotubes, which displayed the PMCA isoform-specific mRNAs 1c, 1d, and 4a, typical of differentiated muscle cells. We conclude that: 1) the distribution of the various PMCA isoform-specific mRNAs and their splicing variants is cell type- and development-specific; 2) expression of the myogenic determination factor myogenin is sufficient to direct alternative splicing generating muscle-specific PMCA mRNA species; and 3) PMCA isoforms and/or splicing variants may play a role in determining functions of terminally differentiated muscle and neuronal cells and possibly during the differentiation process itself.The FASEB Journal 05/1994; 8(6):428-35. · 5.70 Impact Factor - Journal of Hypertension - J HYPERTENSION. 01/1993; 11(5).
Top Journals
University of Wuerzburg
Würzburg, Bavaria, Germany
University of Bonn
Bonn, North Rhine-Westphalia, Germany