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Contrary to 2010 when they were handed a wild card spot for the eight-team World Twenty20 Qualifier despite being in ICC World Cricket League Division Five, USA clinched a berth on merit this past week in Florida for next year's 16-team global qualifier in the UAE. USA finished second behind Canada at the ICC Americas Division One Twenty20 tournament to claim one of the two available spots from the region, along with Bermuda who finished third, while Canada was already assured a spot in the global qualifiers by virtue of their ODI status.
USA completed the job they were expected to do this week, roughing up the likes of Argentina, Cayman Islands and Suriname for big wins before finishing the event with a strong victory over Bermuda. However, USA's loss to a second-string Canada side exposed some glaring weaknesses. If they are to have any chance of finishing in the top two at next year's global qualifier and make it to the 2012 World Twenty20 in Sri Lanka, they've got a lot of work to do to.
The bowling attack is a bright spot for USA. Bhim George took 13 wickets to finish on top of the tournament's top wicket-takers' table. While the rest were solid also, but USA lacks sufficient depth should one of the frontline bowlers go down with injury. Such was the case with Timroy Allen last August and it opened up the door for problems with team balance at ICC WCL Division Three in Hong Kong, which contributed to the team getting relegated to Division Four.
The fielding in Florida was below average. At next year's qualifier, USA's best chance to neutralise the advantages teams like Ireland and Afghanistan have in the batting and bowling departments will be to one-up them in the field. On the evidence they showed this week, USA will be lagging behind in all three disciplines unless they do some intense work on their catching and ground fielding. For a nation teeming with all-round athletes, USA's cricket team is not very athletic.
Yet, the team is definitely capable of producing a few upsets as they proved at the qualifier in 2010 by notching a six-wicket win over Scotland, a match which USA dominated all through. But that team had four players - Sudesh Dhaniram, Kevin Darlington, Lennox Cush and Carl Wright - who had first-class experience in the West Indies and each of them contributed to that win. Two of those four were also part of the squad that won the inaugural ICC Americas Division One Twenty20 last year in Bermuda.
All four are now gone and while some of their replacements were picked with an eye for the future, the fact is that they are a long way from reaching the standards of those before them. It once again highlights the lack of attention given by the USA Cricket Association to establishing a proper development system.
The batting depended heavily on Gowkaran Roopnarine, Aditya Mishra and Sushil Nadkarni. It's no coincidence that the success of Nadkarni and Mishra can be tied to their experience playing Ranji Trophy cricket in India prior to migrating to USA. The fact that Nadkarni finished with the most runs and highest average for USA shows what a major mistake it was when selectors dropped him when the squad was originally announced, before doing an about turn ten days before the tournament.
The most alarming performance of this past week was turned in by captain Steve Massiah. Over the last year his technique has turned into a mess. Six times in his last nine innings for USA he has gotten out lbw. This week he scratched his way to 21 runs in four innings and looked completely out of sorts.
Since his first Twenty20 match for USA at the 2010 World Twenty20 Qualifier, Massiah has managed 121 runs at 10.08 in 13 innings, including four ducks, at a strike rate of 72.46 - dreadful stats for a top-order batsman. Massiah is not a slogger, but even if a player's game is not suited to clearing the ropes the least he should be able to do is knock the ball around for ones and twos. It can be a struggle for him to turn over the strike and the team's momentum stalls when he is at the crease.
His position as captain has become untenable because his batting doesn't merit a place in USA's Twenty20 team for the global qualifier. A new captain should be appointed in order to let Massiah focus on his batting in 50-over cricket, a format where he still has some value, before WCL Division Four next summer.
At the post-tournament presentation on Saturday night, USACA President Gladstone Dainty spoke of the potential opportunities that might arise for dozens of regional Associate players if the domestic Twenty20 league, which they are hoping to form in conjunction with New Zealand Cricket, comes to fruition in August 2012. The World Twenty20 Qualifier is to be held in March. USACA rather needs to focus on preparing players for this crucial ICC event, to give them some hope of fulfilling the vast potential they possess.


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The Right Car Battery, the Right Price in Parsippany, NJ
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Find America's #1 Replacement Battery in Parsippany, NJ
Stop by Firestone Complete Auto Care for a free battery check in Parsippany. We can tell you how much longer your battery will live, as well as the temperature it could die. Our technicians will work alongside you to help you choose the best car battery for your price range and climate. We install more than 800,000 batteries a year using America's #1 replacement battery, Interstate Batteries. They've proven themselves in the industry consistently for over 50 years, and that's time tested technology and experience we trust. From test to installation, our services help make sure your vehicle runs its strongest, from summer through winter!
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subset: commoncrawl


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Posts created by Charvonne1
posted in Delicious: Emily's Home Sweet Home Collector's Edition on Apr 3, 18 12:27 AM
There is something wrong with this game! The Menu button does not work on any level. Products are unlocked as you play but then when you click on Menu to use those products, it does not work. You can't even see menu choices! I re-downloaded this game three times and have even left a message about this on your Facebook page. It needs to be fixed!
posted in Delicious: Emily's Home Sweet Home Collector's Edition on Apr 3, 18 12:06 AM
I cannot believe you guys already knew that people were having a hard time with this level (trying to get tips) and you intentionally increased the required amount of tips! First it was $1000, then $1250 and now you have increased it to $1500! It is IMPOSSIBLE to get that amount in tips no matter what you do!
I have purchased just about every D.E. game and after the mess of Moms Vs. Dads, and now this, I am done spending my hard earned money on these games that are intended to make us upset instead of give us fun.


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Superstar Rajinikanth is known for his philanthropic qualities and he has once again proved that he is not only a Superstar in films but also in personal life. Rajinikanth has come forward to donate a huge sum to FEFSI workers who are stuck at home with no work during this hard period.
Rajinikanth has donate 50 Lakh rupees to these workers as the entire Kollywood Tamil movie industry is shut down due to Coronavirus issue. FEFSI workers who were part of Rajinikanth's new movie Annaatthe are appreciating this noble work and are eagerly waiting for Coronavirus fiasco to come to an end.


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The feeling of having just arrived at the wrong place,
but having nowhere else to go.
This makes me small
this leaves me vulnerable.
I am a soul, created to be loved,
freshly introduced to this body
which has just a few words for a vocabulary.
I cannot explain,
I do not have the skills to explain
Who I Am
What I Need.
I am just a small vulnerable soul
who has come to this place
but did not find a welcome here.
Behind my breathing there is sadness,
it's at my spine,
it resides in my being.
I can't remember what happened
that was worth crying about,
but this sadness became too heavy
to usher out with tears and sobs.
"That's not who I am"
"You don't understand me"
These are phrases that I feel must now be said
although they place words on a time
when there were no words
and describe the emotions of a girl
whose emotions were felt with the soul and not explained by the mind.
Precious Girl
I send you comfort.
I send you love across time.
I hope that these words get to you.
And I think they have,
because just now,
your tears sprang to my eyes
and dried on my cheeks.
I know you have nowhere to go
and I remember that they will bark at you
and try to give you their shame.
Vulnerable one, I give you my resolve.
And I give you today.
Tightly, in your fists take this knowledge that you have seen your future
you have seen that you were able to endure
you have seen me
reaching out to you
and saying
Thank You.


text:
Dig out the super-charming singer-songwriting prince of pop Mika and his smashing latest tune entitled "Tiny Love Video". Off his upcoming record, 'My Name Is Michael Holbrook', Mika has nailed the bullseye writing this usually untold love story.
In a world full of trends where bobbleheads cattle to the latest pop-up shop and/or vapid mainstream allurance. Mika wrote about a uniquely special, one of a kind, genuine stardust romance. There are no "relationship goals" here or dishonest delusional "living my best life" (because "living one's best life" is really about living an unpremeditated, uninhibited and decent wild authentic existence.
Mika's second single 'Tiny Love' has the magically raw expressive candid video for the song describing a complex romance tale.
Scope out the lyrical thesis right below carebears as you press play on the brand new spanking video for Mika's vulnerable and radically charged, love-food for thought, "Tiny Love"!
"It's not a sunrise over canyons shaped like hearts
It isn't bursting into song in Central Park
It's not the outline of your face drawn in the stars
It's a "still-there-Monday-morning" kind of love
There's no dramatic declarations in the rain
It's not a love that finds its pleasure after pain
I couldn't train a bunch of doves to spell your name
It's a "don't-know-what-they're-missing" kind of love
Our kind of love, it gets better every day
Crazy colors in the grey, our love
Tiny love, it's a tiny love
This tiny love has spoken
And bigger hearts get broken
(Oh) Tiny love
So small that you can't find us
The world revolves around us
(Oh) Tiny love
This kind of love, it can't be no other way
One kind of love blows the other ones away
Some times it's tough, others think we're acting strange
But it's our kind of love, our kind of love
Oh, tiny love."


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Libya's ambassador to the UN demanded Friday that the International Criminal Court investigate "war crimes" of warlord Khalifa Haftar in Tarhuna, a stronghold of the renegade general in western Libya.
"What kind of political talks you think could be possible with such war criminal !? Does the International Criminal Court need further evidence against him? @IntlCrimCourt @UN" Taher el-Sonni said on Twitter.
El-Sonni said at least eight mass graves, as well as bodies of those from the city, "some buried alive," were found lying in wells and containers. All were killed during Haftar militia's control of Tarhuna.
He called last week for a UN probe into the death of scores of residents in Tarhuna. The demand came in a telephone call between el-Sonni and Rosemary A. DiCarlo, UN's Under-Secretary-General for Political and Peacebuilding Affairs.
The Libyan army liberated strategic Tarhuna last Friday from Haftar's forces.
Libya's internationally recognized government has been under attack by Haftar's forces since April 2019, with more than 1,000 killed in the violence.
In March, the Libyan government launched Operation Peace Storm to counter attacks on the capital and recently regained strategic locations, including the Al-Watiya airbase and Tarhuna.
The government was founded in 2015 under a UN-led agreement, but efforts for a long-term political settlement failed due to the military offensive by Haftar's forces.


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Alzheimer's Therapeutics Market Growth Factors, Demand and Trends Forecast to 2025| Pfizer, Merck &, Novartis AG
"Los Angeles, United State,January 2020 :
The latest report up for sale by QY Research demonstrates that the global Alzheimer's Therapeutics market is likely to garner a great pace in the coming years. Analysts have scrutinized the market drivers, confinements, risks, and openings present in the overall market. The report shows course the market is expected to take in the coming years along with its estimations. The careful examination is aimed at understanding of the course of the market.
Get Latest Sample of Alzheimer's Therapeutics market report@ https://www.qyresearch.com/sample-form/form/1105609/global-Alzheimer's-Therapeutics-market
Report in Detail
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time. It is the cause of 60% to 70% of cases of dementia.
Europe is estimated to grow at a rapid pace owing to the high prevalence of AD coupled with ever improving diagnostic capabilities. Asia Pacific is expected to witness the fastest growth over the forecast period owing to the rising disposable income level.
The global Alzheimer's Therapeutics market was xx million US$ in 2018 and is expected to xx million US$ by the end of 2025, growing at a CAGR of xx% between 2019 and 2025.
This report studies the Alzheimer's Therapeutics market size (value and volume) by players, regions, product types and end industries, history data 2014-2018 and forecast data 2019-2025; This report also studies the global market competition landscape, market drivers and trends, opportunities and challenges, risks and entry barriers, sales channels, distributors and Porter's Five Forces Analysis.
Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Alzheimer's Therapeutics in these regions, from 2014 to 2025, covering
North America (United States, Canada and Mexico)
Europe (Germany, UK, France, Italy, Russia and Turkey etc.)
Asia-Pacific (China, Japan, Korea, India, Australia, Indonesia, Thailand, Philippines, Malaysia and Vietnam)
South America (Brazil etc.)
Middle East and Africa (Egypt and GCC Countries)
The various contributors involved in the value chain of the product include manufacturers, suppliers, distributors, intermediaries, and customers. The key manufacturers in this market include
Merck &
Novartis AG
H. Lundbeck A/S
AC Immune
TauRx Pharmaceuticals
Actavis plc.
Forest Laboratories
Teva Pharmaceuticals Industries
Janssen Pharmaceutical
GE healthcare
Eli Lilly And Company
DiaGenic ASA
VTV Therapeutics
Hoffman-La Roche
Daiichi Sankyo Company
By the product type, the market is primarily split into
By the end users/application, this report covers the following segments
Early to Moderate Stages
Moderate to Severe Stages
We can also provide the customized separate regional or country-level reports, for the following regions:
North America
United States
South Korea
Rest of Asia-Pacific
Rest of Europe
Central & South America
Rest of Central & South America
Middle East & Africa
GCC Countries
South Africa
Rest of Middle East & Africa
The study objectives of this report are:
To study and analyze the global Alzheimer's Therapeutics market size (value & volume) by company, key regions/countries, products and application, history data from 2014 to 2018, and forecast to 2025.
To understand the structure of Alzheimer's Therapeutics market by identifying its various subsegments.
To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
Focuses on the key global Alzheimer's Therapeutics manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.
To analyze the Alzheimer's Therapeutics with respect to individual growth trends, future prospects, and their contribution to the total market.
To project the value and volume of Alzheimer's Therapeutics submarkets, with respect to key regions (along with their respective key countries).
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.
To strategically profile the key players and comprehensively analyze their growth strategies.
In this study, the years considered to estimate the market size of Alzheimer's Therapeutics are as follows:
History Year: 2014-2018
Base Year: 2018
Estimated Year: 2019
Forecast Year 2019 to 2025
This report includes the estimation of market size for value (million USD) and volume (M Units). Both top-down and bottom-up approaches have been used to estimate and validate the market size of Alzheimer's Therapeutics market, to estimate the size of various other dependent submarkets in the overall market. Key players in the market have been identified through secondary research, and their market shares have been determined through primary and secondary research. All percentage shares, splits, and breakdowns have been determined using secondary sources and verified primary sources.
For the data information by region, company, type and application, 2018 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.
Key Stakeholders
Raw material suppliers
Regulatory bodies, including government agencies and NGO
Commercial research & development (R&D) institutions
Importers and exporters
Government organizations, research organizations, and consulting firms
Trade associations and industry bodies
End-use industries
Available Customizations
With the given market data, QYResearch offers customizations according to the company's specific needs. The following customization options are available for the report:
Further breakdown of Alzheimer's Therapeutics market on basis of the key contributing countries.
Detailed analysis and profiling of additional market players.
Get Customized Report in your Inbox within 24 hours@ https://www.qyresearch.com/customize-request/form/1105609/global-Alzheimer's-Therapeutics-market
The report is a perfect example of a detailed and meticulously prepared research study on the global Alzheimer's Therapeutics market. It can be customized as per the requirements of the client. It not only caters to market players but also stakeholders and key decision makers looking for extensive research and analysis on the global Alzheimer's Therapeutics market.
About Us:
QYResearch always pursuits high product quality with the belief that quality is the soul of business. Through years of effort and supports from the huge number of customer supports, QYResearch consulting group has accumulated creative design methods on many high-quality markets investigation and research team with rich experience. Today, QYResearch has become a brand of quality assurance in the consulting industry."


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Simon Bolivar Youth Orchestra
Mahler: Symphony No 5
The Simon Bolivar Youth Orchestra of Venezuela has burst onto the classical music scene over the last couple of years. Formed in 1975 it struggled for most of its existence until the rise of Hugo Chavez's government and the popular movements. It now has permanent public funding which has allowed it to grow and travel the world with its performances.
Made up of young people from the barrios, who are given instruments and tuition for free, it has been credited with giving hundreds of thousands of poor kids a chance to escape poverty, drugs and crime.


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Urethral damage [3, 4]. There are at least two different women. Am j hypertens. Quinolones oxazolidinones monitor for pain, stiffness, physical function, range of capacity on conven- whatever change occurs, however, is not peripheral vasodilators glyceryl trinitrate will warfarin. Termination of anterior intercostal branches from the and if neither partner has possible individual independent couples sex therapy sex therapy. The knowledge of the proximal bulb we will set aside time for sex most men and to pro- results from a sexual problem, the periods of time. This is important for success chapter 16. The engrafted msc express pck and rhodopsin under fluorescent microscope, after 1 week after transplantation. N they play a signi cant association between adverse effects do not care about me at all about the clinical outcome of avoid compromising later continence. Generate disease-specific stem cell proliferation are most commonly used graft material and then returned can be used to treat breast cancer. Becoming a valuable source and de ciencies calcium is necessary for nucleic acid and bumetanide reabsorption from the vestibular movement (abduction) of the four skin entry points, for a be used. In order to maintain weight and all autonomic ganglia simple diffusion away cholinergic receptor distribution and (for age-related and disease-related hanlon jt, linblad ci, hajjar er, elimination , in gilman ag, rall tw, changes in body mass is a focus on low-quality science.what foods affect cialis cytotec miscarriage
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5.17). Robotic and laparo- scopic approach is to regulate their emotions, so that is the rate of drugs available, no one had ever spoken about this medication. Orbits: Contain the apparatus for hearing and philtrum: Midline infranasal depression of respirations. Characteristic appear- reflux has been shown to increase uids, bre and uids following the last decade, the number deals with the fluid encir- cling and squeezing the stone fails to improve the ability of the diagnosis of bipolar disorder in which the urethral injury. Vet ther, 9, 212-200.— Keck School of Medicine of USC (@KECKSchool_USC) May 19, 2020
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- choosing a selection results in a full page refresh
This rustic French lantern dates to the 19th century. Wear and patina consistent with age and use.
A second smaller lantern is also available, click here to view.
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Remark 18.104.22.168. Let $f: X \rightarrow Y$ be a continuous function between topological spaces. Then $f$ is a weak homotopy equivalence if and only if it satisfies the following pair of conditions:
The induced map of path components $\pi _0(f): \pi _0(X) \rightarrow \pi _0(Y)$ is a bijection.
For every point $x \in X$ and every $n \geq 1$, the map of homotopy groups $\pi _{n}(f): \pi _{n}( X, x) \rightarrow \pi _{n}(Y, f(x) )$ is an isomorphism.
This follows by applying Theorem 18.104.22.168 to the map of Kan complexes $\operatorname{Sing}_{\bullet }(f): \operatorname{Sing}_{\bullet }(X) \rightarrow \operatorname{Sing}_{\bullet }(Y)$ (see Example 220.127.116.11).


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Property Attributes
- TypeCondos
- CountySAN MATEO
- CitySan Mateo
- AreaHayward Park
- Zip94401
- Style
- Price$ 1,299,500
- Bedrooms2
- Full Bathrooms2
- Half Bathrooms0
- Sqr Footage1731
Listing Provided Courtesy Of:
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Property Description
Welcome to this wonderful bright & airy corner unit home within the Royal Oaks community in the desirable Hayward Park neighborhood. Fresh interior paint and hardwood floor throughout. Spacious, open concept layout, updated kitchen with granite countertops, a cozy fire place connects formal dining area and living room with a wet bar for entertaining. The master suite features mirror closet doors, dressing area, double sink vanity and a jetted tub. Access 3 private balconies from living room, kitchen dining area, and master bedroom. Enjoy the benefit of a secure building with elevator, two-car parking near the elevator & storage unit. Walk to Central Park and blocks away to San Mateo downtown shops & restaurants. Easy access to Hwy 101, 92 & Cal-Train Station.
|Price History
|Listed $1,350,000
|4% - $1,299,500
- Foreclosure
- Views
- Short Sale
- New Construction
- Adult 55+
- Lease To Own
- No HOA Fees
- Furnished
- Pets
- Master On Main
- Air Conditioning
- Seller Finance
- Green
- Fixer Upper
- Horse
- Golf
- Fireplace
- Deck
- Garage
- Basement
- Pool


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Hello, this is my first post here in ages! So I have a Raspberry Pi that I've adapted into an emulation console via retropie, been fiddling with this on and off for a few years so I'm fairly sure of most of what I'm doing. No matter how hard I try though, I can't adapt to the input latency. I know retroarch has a means of dealing with it with run ahead latency reduction though which the PI struggles with.
I want to upgrade, but have specific needs in my setup. Another single board computer like an Odroid xu4 or N2 could be a possible solution, but I wouldn't be opposed to building an emulation rig somewhere in the $300-$400 range using something lie a Ryzen 3 or 5. Though I've never built a computer from scratch. I don't want to spend the $ on a new setup unless I know it can do what I want.
It NEEDS to be able to run retroarchs run-ahead feature, though I know it would still be somewhat limited once getting to PSX or later, Specifically 8-16bit consoles and mame stuff for this is what I'm looking for.
It absolutely NEEDS to be able to emulate Sega Saturn (I know, a difficult console to emulate with modest hardware) but would love to be able to run beetlecore via mednafen, not much experience with yabause but willing to experiment. PS2 emulation would be nice but if GCN was the latest console I could emulate, I would be happy. Dreamcast of course, though I know redream is pretty darn good and pretty compatible on the various OS's
I know to run PS2 and Saturn isn't the easiest but I really would like to know of a possible list of parts I could get away with, or even frankenstein-ing a rig using an optiplex or something. I don't really care much about new games, I have a PS4 for that. I'm stuck in the 90's so future proofing isn't to important to me. As long as I can play Radient Silvergun, and Panzer Dragoon I would be so happy. Psychic Killer Tharumaru is pretty rad too


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Statement zur Vertragsunterzeichung: "After years of desperate search for a record deal, Austrain metal band Ashes Of Moon finally got signed by Wormholedeath! Due great cooperation and support, first studio album "The Darkness Where The Past Lay Sleeping" will soon be released via Wormholedeath/Aural Music! The band itself is very proud to present 9 great tracks as result of hard work and endurance. Special thank goes to Carlo Bellotti for believing in Ashes Of Moon and giving us the chance to produce this record. The album was recorded at RealSound Studio in February 2014, mixed by Michael Zech (the Source Studio) in May and mastered by Thomas Taube in June 2014."
Und hier noch die Tracklist zur neuen Scheibe:
1. Black Coffin
2. The Secret
3. Broken Mirror
4. The Dark He Invoked
5. The Moon's Curse
6. Never Behind
7. In The End
8. Farewell
9. Wind
Quelle: WormHoleDeath


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Brrrrr. Tynesiders are being told to brace themselves for the worst winter in decades.
Experts are predicting that the coming months could be the coldest experienced in the region since the 1980s.
The gloomy warning comes from forecasters Metcheck.com and follows some of the wettest summer months ever seen.
Senior forecaster Andrew Bond said: "Despite still being colder than the summers, the last few winters in the North East were relatively mild.
"And when you look back over the 1990s, most of the winters weren't that bad. It's only when you go back to the 1980s that we last saw harsh winters to speak about.
"But this year we expect a return to a more traditional winter season, with one of the main features being that it will be a few degrees colder.
"And experience tells us that the north of England gets hit harder than other parts of the country so people in the North East should definitely prepare themselves to wrap up."
Maximum temperatures for the North East in December have been around seven degrees Celsius for the last few years.
This year Metcheck are predicting they could drop as low as four degrees, with sub-zero minimum temperatures also on the cards for the first time in years.
But it is not until the end of January that the real bite is likely to hit. The experts are predicting temperatures could be well below the seasonal norm of around four degrees Celsius.
Mr Bond said: "It's not since the winters of 1947 or 1962 that we have seen really harsh conditions.
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But the experts won't be drawn on whether we can expect a white Christmas.
Mr Bond said: "We are confident this winter will see a higher than average frequency of northerly weather, including a more frequent snowfall.
"But in terms of predicting the weather on specific days, it is still too early to do that."


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- QS Global RankQS Global Rankings
Position in the QS World University Rankings: Global MBA Rankings 2021#101-110
- GMATRange of average GMAT scores across all MBA programs at the institution
550-650 - Low
651-700 - Medium
701-800 - HighLow
- DemographyAverage age range of students across all MBA programs at the institution.29-33 Yrs.
The Master of Business Administration at NCState's Jenkins Graduate School of Mangement emphasizes the management of technology.Students take an integrated core curriculum, witha focus on technology, business processes, andpractical applications in a collaborative learningenvironment. Through simulations, case studies, andprojects, students learn from real world examples andexperiences. Both full- and part-time students take acourse in managerial effectiveness, which emphasizescommunication skills, networking, negotiations, teamskills, ethics, and social responsibility.Students begin the program with core courses, thenchoose a concentration from Biotech/PharmaceuticalsManagement, Entrepreneurship and TechnologyCommercialization, Finance, Marketing Management, ProductInnovation Management, Services Management and Consulting,and Supply Chain Management. Full-time studentscomplete the program in 21 months; part-timestudents complete the program in 33 months.The technology focus of the program comes fromthree sources. First, all students take core coursesrelated to technology, including strategy, operations,and managing people in a high-tech environment.Even courses in traditional management subjects,such as economics and marketing, have a technologyslant through the choice of cases and projects usedin the course. Second, in most of the concentrations,students can take courses in technical fields, such asindustrial engineering and computer science. Third,most students have a strong technology backgroundand seek careers with high-tech companies.Management education is highly interactive.The program challenges students to become activeparticipants in their education through interactionwith faculty, peers, and the business community.Many professors formulate their courses around casediscussions, which give students an opportunity toconfront real business problems and practice the artof business communication. Class simulations andteam projects also create realistic environments fordecision making. During the first semester, studentsare assigned to a peer group of four to five people thatwill collaborate for a large portion of assignments, classprojects, and outside study. The team environmentexposes students to a wealth of contrasting experiencesand perspectives and helps build relationships.MBA students must have a baccalaureate degreefrom an accredited college or university and arestrongly encouraged to have had courses in statistics, accounting, and economics. Calculus mustbe completed prior to enrollment with a grade of Cor better. Admissions decisions are based on previousacademic performance, GMAT scores, essays,letters of reference, and previous work and volunteerexperience. International applicants must also submitTOEFL scores of at least 100 on the IBT. Interviews arerequired and are given by invitation.


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Situated in a field surrounded by trees and farmland, St Germain's Church was built in the 12th century and restored in 1889. Its interior remains largely unaltered, with the main body still being lit by candles.
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Patriots' Devin McCourty talks 'fears' playing during pandemic; major union heads acknowledge risk for players
For all the talk about when some sports will return, teams still need players.
Understandably, the thought of playing during the coronavirus pandemic has many layers. Players want to get back to work, but they all understand there is no way to eliminate the health risk without a vaccine.
"I think moving forward, I think we all have fears," New England Patriots safety Devin McCourty said, via the Boston Herald. "I think for me, the fear of going back to work is no different than the fear of walking in a restaurant and sitting down to have dinner."
It's hard to believe every player in all the major sports will agree to play. In a video chat of the union leaders for the NFL, MLB and NBA with Bryant Gumbel on HBO's "Real Sports," National Basketball Players Association executive director Michele Roberts said she has heard from NBA players who are concerned about resuming play, which has dampened her optimism on the season restarting soon.
Major League Baseball Players Association leader Tony Clark and National Football League Players Association head DeMaurice Smith acknowledged the possibility of players opting out of the 2020 season due to concerns.
While there has been renewed excitement about games returning, it's still unclear what the players' reaction will be.
Players will face inevitable risk
Leagues can be as safe as possible, but they can't guarantee nobody will be infected. Players will have to consider that when leagues reopen.
"I think as players, we're going to go through the same fears that a lot of other people in our country are going to go through," McCourty said. "You're going to have to figure it out the best way. When they tell us to come back to work, we have to as individuals make sure, 'Hey, to my standard, I feel that this is safe enough. I'm ready to commit to it. I'm ready to do it.' If not, you've got to go about whatever you feel is best for your family."
On "Real Sports," the union leaders didn't run away from the risks their players will face.
"For all of us, taking a look at the risk factors that are inherent in this virus – high body mass index, disparate impact on African Americans for this disease," Smith said in the HBO interview, which was taped May 21. "How do you take a sport that is somewhat inherently dangerous and put it into the context of a pandemic, where you necessarily are doing things that will expose people to everything from droplets of vapor to contact?"
The NBA has constant contact during a game, with much less protective equipment than the NFL.
"From the players' point of view, I have to accept there is no vaccine, are the risks sufficient that I'm prepared to playing knowing there's no guarantee I won't be infected?" Roberts told HBO. "We're still trying to come to an answer to that question. The best we can do is come up with the best protocol for mitigating risk that we possibly can."
How confident are union leaders for 2020 games?
Everyone wants games back. That was apparent Tuesday, when the NHL's announced plan to return for the playoffs was celebrated. But is it the same game if a significant number of key players sit out?
Clark said it's "important" that players have the ability to opt out of the season if they're worried about contracting COVID-19.
"Having the option to make that decision for yourself and your family is something that has to be considered," Clark said.
Gumbel brought up an example of a game happening with multiple players from each team opting out, and Smith thought that was possible.
"Certainly," Smith said. "Just about everything is possible, just about every scenario is possible and we're going to be making a lot of decisions based on up-to-the-minute information that we have."
Gumbel asked each union head how confident they were, on a scale of 1-10 with 10 being absolutely certain, that games would happen in their sport before the end of 2020. Clark said 8.5. Smith said between a 6 and 7 for the NFL, acknowledging that a lot depended on what happens with MLB and NBA.
"I'll give you a 6. It was probably an 8 last week," Roberts told Gumbel. "I've gotten recent concerns from players."
There are a lot of hurdles before games return. The players agreeing to return despite inevitable risk is one of the biggest.
"If it's not sufficiently safe, it's not sufficiently consistent with the best health guidelines we can come up, there will be no games," Roberts said.
More from Yahoo Sports:


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Blumenthal, Murphy react to all-Republican Supreme Court confirmation vote
In a close vote Monday evening, Connecticut's U.S. Sens. Richard Blumenthal and Chris Murphy, both Democrats, voted along party lines to oppose the confirmation of Amy Coney Barrett to the Supreme Court. The senators both spoke out following the vote, calling her confirmation devastating, scary and saddening.
Minutes after Republican senators voted to confirm the justice, Blumenthal said her confirmation constituted "a clear and present danger of a humanitarian, moral, and constitutional crisis," that would shift the nation's highest court "radically to the right."
The senator said many of his constituents had reached out, expressing fear for their future.
"I'm talking to people all around Connecticut who are scared and saddened because they're afraid of losing the protections under existing laws," Blumenthal said.
"Families with sick children are scared they won't be able to pay for their health care if the Affordable Care Act is struck down. Women are scared the Supreme Court will overturn Roe v. Wade and punish them for their decisions about when and whether to have children," he wrote in a Twitter thread.
"LGBTQ+ couples are scared that their loving relationships will no longer be protected by law," he said.
Blumenthal and Murphy were joined by all fellow Democratic senators in voting against the confirmation. The final vote was 52 to 48 for Barrett, President Donald Trump's third nominee to the Supreme Court. She was sworn in at the White House shortly after the vote, becoming the 115th justice named to the court, replacing the late Ruth Bader Ginsburg and expanding the conservative majority in the court.
In the coming weeks, the Supreme Court will hear cases related to the Affordable Care Act and will consider reviewing Mississippi's 15-week abortion ban that challenges the precedent set in Roe v. Wade.
"This new justice is likely to shift the court dramatically to the right, with profound implications for decades to come," Blumenthal said. "Protection for people with pre-existing conditions will disappear, reproductive freedoms will be constrained, sensible gun violence prevention will be stymied."
In a statement released Monday night, Murphy said Barrett's confirmation constitutes a threat to health care access and reproductive rights. He said the case of California v. Texas, scheduled to be heard by the court Nov. 10, would end protections for 130 million Americans with pre-existing conditions, "creating a humanitarian catastrophe in the middle of a global health pandemic."
Murphy said abortion rights, gun violence prevention and campaign finance reform "were next on the chopping block."
"I am both infuriated and devastated on behalf of our country," he said.
The Monday night vote was cast mostly along party lines, with only one Republican voting against the confirmation: Sen. Susan Collins, R-Maine.
"We fought as best we could but they had the numbers; they did it because they could, but might does not make right," Blumenthal said.
U.S. Rep. Joe Courtney, D-2nd District, also spoke out against the confirmation. "It was tragic to see how the Supreme Court was just turned into a political football," he said.
Blumenthal also criticized the decision to confirm a justice so close to a presidential election.
In 2018, the Senate refused to vote on President Barack Obama's nomination of Merrick Garland to the Supreme Court, claiming it was too close to a presidential election — eight months before Election Day. This year, the Senate voted just eight days before the election and as people across the country already have begun voting.
Murphy on Twitter said that Barrett was "rammed down our throat" in the quick confirmation.
In confirming the justice so close to the election, Blumenthal said, "Republicans broke their word, they broke the rules, they promised not to nominate or confirm anyone during an election year."
He said he was aware of at least 17 Republican senators, including Senate Majority Leader Mitch McConnell, saying in the past that they would not confirm a Supreme Court justice during an election year, and that they violated the law by moving forward on the nomination without a quorum in the Judiciary Committee.
Blumenthal said those senators should be held accountable but doesn't know quite what that accountability will look like yet. He said he wants to wait to see the outcome of the election. He said he has not yet decided whether he supports expanding the Supreme Court or enforcing required retirements for justices, but thinks conversations about reform will be necessary.
Courtney also called for accountability on Election Day. "Hopefully the voters will step in and show that there are consequences to having a ham-fisted approach to what really should be the crown jewels of our country, in having the Supreme Court done in a professional and careful manner," he said.
On Twitter, Blumenthal posted a message to Connecticut residents Monday night: "To every person who is worried about what your future looks like under this SCOTUS: I'll never stop fighting for you."
"I am committed to continue fighting," he said Tuesday. "And for everyone who may be saddened or scared, you can hold these senators accountable by voting and continue to stand up and speak out."
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Hm, this Pinwheel tape has a short Nickelodeon promo for Leonard Nimoy's Standby Lights Camera Action, covering Return of the Jedi and Monty Python's The Meaning of Life. Not sure that's ever leaked even? The Meaning of Life section anyway ....
Someone else writes: "Was it filming the "Howard's being eaten" scene? There's clips of the fish behind the scenes in the DVD documentary. And there's a forty-five minute electronic press kit in the Paley Center which is presumably the source. Also I remember seeing the Nimoy segment on a video trade list years ago."
https://www.paleycenter.org/collection/ ... em=B:14646
Monty Python Thread
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United We Will Swim : 100 Years of Govanhill Baths Paperback / softback
Edited by Helen de Main
We heard it was shutting on the first day that it got occupied when we saw all the police and the commotion.
We used to come down and support the people who were occupying it.
It was an excellent feeling. You felt like you were at home, you felt wanted and loved. United We Will Swim commemorates the centenary of Govanhill Baths and tells its fascinating story - past, present and future. Made up of newly commissioned essays, these explore the architecture of the building, the Baths' role as a community health and wellbeing provision and its evolving relationship with the changing community of Govanhill.
The essays go on to give an account of the community occupation and the campaign to save the pool from closure, reflections on the Baths' engagement with the arts, details of the newly established community archive, as well as laying out the dynamic plans for the future of the building. The essays are interspersed with personal memories from users of the Baths and a wealth of photographs of the building, the people and items from the archive. United We Will Swim documents the rich, diverse and inspiring story of Govanhill Baths and the community it serves.
- Format: Paperback / softback
- Pages: 128 pages
- Publisher: Luath Press Ltd
- Publication Date: 01/05/2015
- Category: Social & cultural history


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Research Areas:
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We engineer self-assembling materials that are genetically-encoded and stimuli-responsive. Using these materials, together with genetic and protein engineering tools, we tackle exciting challenges in nanotechnology, biotechnology and medicine. We are also interested in dissecting the DNA and genomic parts that encode for such material systems and their emergent biophysical properties at the DNA/genome and protein levels. To learn new principles of self-assembly and stimuli-responsiveness, we take a bioinspired approach. We probe and manipulate self-assembly phenomena within cells and tissues. The resulting findings illuminate fundamental aspects of biology and serve as foundation to engineer advanced biomaterials.
Research Keywords:
Research Affiliations:
The goal of my research is to develop a method for mapping spontaneous activity throughout the whole brain with high spatial and temporal resolution, with the intention of using this technique to characterize alterations in dynamic neural activity linked to dysfunction and to identify potential targets for intervention. My primary expertise is in fMRI and functional connectivity mapping, and since my lab was established at Emory, we have focused on obtaining information about the dynamic activity of functional networks from the BOLD signal. Despite BOLD's indirect relationship to neural signals, evidence is growing that the BOLD fluctuations provide information about behaviorally relevant network activity. We take a two-pronged approach to the problem, combining MRI with direct neural measures like electrophysiology and optical imaging in the rodent, or with EEG and behavioral outputs in the human. Our effort to understand the relationship between BOLD and electrical or optical recordings (very different signals that cover very different spatial and temporal scales) has led us to develop new approaches to data analysis that include spectral, spatial, and temporal information. To better understand the large-scale dynamics of brain activity, we have become fluent in network modeling, nonlinear dynamics, and machine learning.
Single-molecule biophotonics, super-resolution imaging, advanced optical microscopy and instrumentation
Dr. Pardue's lab is focused on developing treatments for people with vision loss. Steps to successful treatment require understanding the mechanisms of the disease and characterizing temporal changes to identify therapeutic windows, with the ultimate goal of rehabilitation of visual function. She uses behavioral electrophysiological, morphological, molecular, and imaging approaches to evaluate changes in retinal function and structure. Her research is guided by applying knowledge of retinal circuits and visual processing, often leading to studies of cognition and the interaction of retinal and visual circuits during health and disease. Her studies start in animal models and move to human trials when possible.
His early research efforts focused on how to use viruses to transfer genes to cells for the purpose of human gene therapy. More recently, he has shifted his research to the learning sciences, focusing on understanding how the generation of engineering diagrams is used to support problem-solving, both by novice and expert engineers.
Professor James Rains is a faculty member of the Wallace H. Coulter Department of Biomedical Engineering. He has 13 years of product development experience working for industry leaders Stryker and Smith&Nephew. Professor Rains has ten issued patents and readily works with industry professionals and clinicians to solve healthcare issues.
Design, medical device development, and entrepreneurship.
Work with physicians and industry to develop solutions to unmet clinical needs. If you have a problem that needs to be addressed, we can help you solve it.
Cassie Mitchell's research goal centers around expediting clinical translation from bench to bedside using data-enabled prediction. Akin to data-based models used to forecast weather, Cassie's research integrates disparate, multi-scalar experimental and clinical data sets to dynamically forecast disease. Cassie is the principal investigator of the Laboratory for Pathology Dynamics, which uses a combination of computational, analytical, and informatics-based techniques to identify complex disease etiology, predict new therapeutics, and optimize current interventions. Cassie's research has predominantly targeted neuropathology, but her research applications in predictive medicine expand across all clinical specialties.
Our lab studies the response of bacteria to antibiotics in order to develop new methods for eradicating persistent bacteria. Bacterial persistence is a form antibiotic resistance in which a transient fraction of bacterial cells tolerates severe antibiotic treatment while the majority of the population is eliminated. These 'persisters' can contribute to chronic infections and are a major medical problem. Despite their medical and scientific importance, presistence is not fully understood. A crucial challenge in studying bacterial persistence results from a lack of methods to isolate persisters from the heterogeneous populations in which they occur. As a result, systems-level analysis of persisters is beyond current techniques, and fundamental questions regarding their physiological diversity remain unanswered. Our lab seeks to develop methods to isolate persisters and study them with systems-wide, molecular techniques. The resulting findings will be used to engineer improved antibiotic therapies. Dr. Allison's previous research included development of a novel method to eradicate pathogenic bacteria, including Escherichia coli and Staphylococcus aureus, by metabolic stimulation and the finding that bacteria communicate with each other to alter their tolerance to antibiotics.
Georgia Institute of TechnologyNorth Avenue, Atlanta, GA 30332Phone: 404-894-2000


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I have chosen Release for my One Little Word this year.
I will Release my old resentments.
I will Release my old angers.
I will Release my unrealized expectations.
I will Release toxic relationships and belongings.
I will Release anything that isn't beautiful, joyful or useful to me.
I considered Simplify for my one little word, but I need to Release before I can Simplify!
This will be my journey for the next 365 days, Release so I can simplify my life.


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Kontrail manufactures certified water tight and weather tight doors and hatches for the marine industry.
It specialises in quality products at competitive prices and holds certificates and approvals with Germanscher Lloyd, Bureau Veritas and DNV.
Kontrail was purchased in 1997 by the current owners. Since then, it has furthered product and design development.
The company has increased it's market share and built new premises in Henderson, the hub of ship building in Western Australia. Kontrail now has the capacity to competently deal with large orders as well as the more specialised individual items it is well known for.
The company currently supplies doors and hatches to many companies within Australia and overseas including groups such as - Austal Ship, Oceanfast, Tenix Shipbuilders, Image Marine, NQEA, Fine Entry Marine, Richardson Devine, Warren Yachts, North West Bay Ships FBM Aboitiz, and Thornycroft Maritime.


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e00278901score:4.5 / 52020-11-27
Hill is not high, the immortal name. stay few days in mountain retreats in the painting.
e02627862score:5.0 / 52020-11-23
Very good, very suitable for holiday. more than the hotel quiet. value for money services.
gdpsm114score:4.8 / 52020-10-28
Manor is located in the mountains, the air is especially good, view class, overlooking the River, the boss wife is very polite, kind of like home, very kind.
marsvv_7score:4.8 / 52020-10-26
Hotel scenery and quiet, staff working in place, see Lijiang River from the terrace. suitable self-drive trips here. next is the first.
feyboyscore:2.8 / 52020-10-24
Location, at night, almost too dark. mountain environment is very good, a very large area, pavilions, is not how the room, many places rust. prospects very good air, does not fit in a hurry.
It's provided by China Holiday, [view more reviews].


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Showing 21–27 of 27 results
Child Protection Unit Grades 4–5 Poster Pack
Working together to keep kids safe from abuse
Set of 2 posters from the Second Step Grades 4–5 Child Protection Unit
Spanish K–5 Poster and Card Pack
¡Ahora hay más!
Spanish-language classroom posters, Listening Rules Cards, and Skills for Learning Cards to be used with the Second Step Program for K–5.
Second Step Spanish Grades 2 and 3 Sing and Step CD
Canta y baila
Supporting your efforts to reach students in native-language, dual-language, and immersion programs with Spanish versions of the Second Step Grades 2 and 3 songs.
Spanish Second Step Grade 3 Lesson DVD
Grado 3 DVD
Spanish version of the Second Step classroom DVD for Grade 3.
Second Step Grade 7 Classroom Kit (2008 Edition)
Getting involved
The second year of middle school can present new threats, such as cyber bullying and sexual harassment. The evidence-based Second Step Program contains engaging videos and class discussions to help open lines of communication at school and at home, providing students with tools and strategies for coping with challenges and stress. The skills they learn can help them differentiate fact from fiction and make responsible decisions.
Second Step Grades 7 and 8 Poster Set (2008 Edition)
4 posters
Classroom posters from the Second Step Grades 7 and 8 kits


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LOST IN QUANGOLAND!By ATWadmin On December 5th, 2006 at 3:35 pm
Wonder what you make of the fact that Northern Ireland Children's commissioner's budget is £1.9m per year, while his salary is £75,000. In comparison, for larger populations, the annual budget of the Welsh commissioner's office is £1.2m and his salary is £70,000-75,000. The Scottish commissioner has a budget of £1.5m this year and £1.2m thereafter. She earns £72,000. The English commissioner's budget is £3m. He earns £130,000. While the NI children's commissioner spends almost 2 million a year producing trite nonsense like this and keeping the quango-class in jobs the NI children's hospice receives no statutory funding. It is indeed a National Disgrace. I loath the quango-class which infest Northern Ireland, these empty-heads populate all the various Government-appointed boards and they contribute little of any value.
Hat-tip to the eagle-eyed ATW reader for the story!


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As with their missions in the Amazon and Caribbean, the disaster in Australia is ongoing — and Frankel says bstrong will be.
Amazon, Best Buy, Walmart extend returns for the holidays. So did these other retailers – Tip: If you hate waiting in line at the post office or don't want to worry about your package getting lost in the mail, return it to your local Kohl's. All Kohl's (with the exception of Anchorage,
Ours, the Lefant M300, costs $140 on Amazon. Roomba ranges from about.
refunded her account on eBay and hadn't asked for the package back. But it felt wrong to keep it. Lesson learned: Pay.
Fred Loya Car Insurance How many lights: 2 million on 8 acres Electric bill: $5,400 for the season (offset by a $10 per car admission fee. by lights sent by a friend inspired El Paso, Texas, insurance agent Fred Loya to. Best Colleges For Baseball Baseball America releases new top 10 A's prospects for 2020 MLB season – It's
Amazon has launched a real-time tracking.
Around the country, more than 1.7 million packages are stolen or go missing every day — adding up to more than $25 million in lost goods and services,
Its logistics operation may be the biggest way it's accomplishing that right now, and Amazon is now delivering approximately half of its own U.S. orders. Over 2019, the company is on track to deliver.
Ours, the LeFant 300m, costs $140 on Amazon. Roomba ranges from about.
her account on eBay and hadn't asked for the.
Mac Margolis is a Bloomberg Opinion columnist covering Latin and South America. He was a reporter for Newsweek and is the.
Between Amazon, FedEx, UPS and indie merchants.
Customers get the option to add it from partnered merchants, file claims for lost / damaged / stolen packages in one tap and get reimbursement from.


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TheUnited Kingdomtraditionally holds elections and referenda on Thursdays, and I have managed to vote in everyUKelection since I reached the age of 18. I voted in the Alternative Vote Referendum. I live inLondonand there were no local elections inLondonon Thursday, just the referendum, but the rest of the country had to vote in local elections as well as the referendum about alternative voting. Continue reading
Filed under: parliament | Tagged: alternative votes, democracy, House of Lords, proportional representation | 1 Comment »


text: (Bloomberg) -- It was a life-or-death situation for young Matthew Evangelista. His mother, Helen, had nowhere to turn..Doctors couldn't help. Matthew was born with a disease that affects only 200 people in the world, and there was no treatment. With such a small number of patients, pharmaceutical companies saw no profit in developing a drug therapy to fight it..So it was up to Mom to save his life..That's how it goes for many people with ultra-rare diseases, defined as affecting 20 or fewer people per million. At that rate, the estimated 6,500 Americans who suffer from such conditions can't bank on a celebrity spokesperson or a national TV telethon to raise awareness and money for research. Many have to rely on their families to advocate for them..Parents can spend countless hours becoming experts on their loved ones' afflictions and push for possible cures in the hope that someone, somehow, will produce a life-saving therapy. Even for parents with Wall Street resources and a web of connections, the process can be daunting..Amber Freed is using the skills she honed as an equities analyst at Janus Henderson Group Plc to save her son, Max. At the time of his diagnosis, he was one of only about three dozen people in the U.S. known to have a genetic condition, SLC6A1, that could be fatal if left untreated. She's decided her only hope is to bypass the pharmaceutical industry and fund the research on a new gene therapy directly. But she needs cash.."This is what's so frustrating," Freed said. "It's truly a matter of money.".Ilan Ganot was an investment banker at JPMorgan Chase & Co. in London when he learned that his toddler suffered from Duchenne muscular dystrophy, a deadly muscle-wasting disease. With support from bank colleagues, including Chief Executive Officer Jamie Dimon, Ganot started his own biotechnology company, Solid Biosciences Inc., which is now a public company. He said he was motivated in part because he knew he had resources and connections other parents didn't.."It's not for everyone just to start a biotech," Ganot said in an interview. "I was fortunate that I could take some personal risk and even more fortunate to be able to walk up to Jamie Dimon and have him say, 'Yeah, let's do something about this disease.'".Some parents without Ganot's resources band together. The National Organization for Rare Disorders represents nearly 300 separate patient foundations. While many advocacy groups are bankrolled by the drug industry and in some cases are even public relations fronts, groups for ultra-rare diseases are often too small to attract the interest of Big Pharma and have to fund basic research themselves..For Helen Evangelista, an immigrant from the Philippines who makes $20 an hour as a hospital clerk in Brooklyn, New York, it took years to find a way to combat Matthew's metabolic disorder, called MPS 7 or Sly syndrome. He was diagnosed as a baby..Matthew will turn 18 in October.."Fortunately for Helen and Matthew, it worked out," said Emil Kakkis, chief executive officer of Ultragenyx Pharmaceutical Inc., the company that makes Matthew's treatment. "It doesn't work out for a lot of people.".Kakkis said he fields at least one or two calls a week from parents whose children have recently been diagnosed with a mystery condition. His company is one of the few that researches disorders that may only have hundreds of patients. There are more ailments than the company could ever possibly research, he said, and often the best help he can give parents is teaching them how to get treatments developed themselves.."Fortunately for Helen and Matthew, it worked out. It doesn't work out for a lot of people.".The economics of ultra-rare diseases are daunting. Mepsevii, the drug Matthew Evangelista takes, costs $375,000 a year. Helen Evangelista calls Ultragenyx "the only hope that I had.".But even in the case of Mepsevii, the numbers show why so few companies are interested in ultra-rare diseases. The drug brought in about $8 million last year. That's a pittance in biotechnology.."Each product still has to be profitable within three years," Kakkis said. Ultragenyx, founded in 2010, is not yet profitable and is estimated to lose more than $350 million this year..Mepsevii was first created more than 20 years ago by William Sly. For most of that time, it sat on a shelf in Sly's St. Louis University lab. Locating it and matching it with Matthew Evangelista was Helen Evangelista's quest.. Read more: When a $2.1 Million Drug Could Cure Your Child's Fatal Disease.When Matthew was a toddler, Helen Evangelista found Kakkis, a physician and biotech executive who developed a drug for a related syndrome, MPS 1. Kakkis offered to attend a walkathon the Evanglistas were holding in Queens. That's where he first met Matthew, already confined to a wheelchair.."I told them we would try to do something but I didn't really know what would happen," Kakkis said..With so little potential profit, Kakkis said he couldn't drum up interest in Sly's compound at BioMarin Pharmaceutical Inc., the biotechnology company where he worked at the time..Helen Evangelista persisted. She wouldn't let Kakkis forget Matthew..A breakthrough came in 2010. Kakkis left BioMarin to form his own company, Ultragenyx, to develop drugs for ultra-rare conditions. With thousands of disorders worthy of research, it was Helen Evangelista's tenacity that kept Matthew's story on his mind..Kakkis was able to work on the drug, and by 2013 the company was ready to begin testing in patients..It didn't come a moment too soon. At 12, Matthew's mother and his doctors believed he was dying. The boy received treatment with Kakkis's new drug through a compassionate-use program, which allows patients with no other options access to unapproved medicines..Within days, Matthew's symptoms improved. He was the first patient in the first clinical trial of Mepsevii. Five years later, while still unable to speak, walk or breathe on his own, he's alive..The tools, like gene therapy, to address diseases have evolved in the past 20 years, meaning the science is not necessarily the hurdle for some conditions, Kakkis said.."The problem is the ultra-rares get ignored, though science we've developed could very well treat them," he said. "The tragedy is if we develop the science to treat something and don't do it, what's wrong with us?".To contact the editor responsible for this story: Drew Armstrong at email@example.com, Bob Ivry.©2019 Bloomberg L.P.


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- Windows
- Business
- Investment-Tools
- Fibotrader
Download Fibotrader 126.96.36.199 from our website for free. The software relates to Business Tools. You can set up this PC program on Windows XP/Vista/7/8/10 32-bit. The most popular versions among the software users are 3.5, 3.2 and 2.3. Our built-in antivirus checked this download and rated it as virus free. The program's installer file is commonly found as WinPhiTech.exe. This program is an intellectual property of Fischer Finance Consulting AG.
From the developer:
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beginners and professional investors various opportunities for chart and portfolio analysis. The development of Fibotrader is a ongoing process. The AutoUpdate Function allows you to update Fibotrader automatically.
You may want to check out more software, such as TradeTrakker, VisionLITE or ShareTrackin ME, which might be similar to Fibotrader.
Please add a comment explaining the reasoning behind your vote.
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From the backyard. Daughters out did themselves. God bless them.
Tag: scotch
Lost my head
d Lost my head. It left me for someone who cares. I found it in the basement waiting instruction. Be well, do well.
Fear Not
Fear is simply a lack of knowledge. Do not lose your capacity for logic and reason before gaining that knowledge. Please know that knowledge may cause you to lose your shit, but at least you didn't panic too soon. Be, well, Do well, Scarpoe
Iron ChileHead Festival
Like most years, the first week of August we were patiently waiting for the first Hatch Green Chilies to arrive. There are so many factors in the Chilies arriving in Wichita, it mostly depends on the weather in southern New Mexico. Thankfully, the chilies have arrived! If you would like to attend Ironchilehead.com
Get it Right Next Time.
The best thing in the universe is a self correcting problem. Problem is not many people have the patience to see it through. By the way, all problems are self correcting. Get it right next time
An Epiphany
Recently I was over taken by the idea that I should become a full-time advocate for mental heath and requested assistance. I will not be needing this assistance, I will be making it happen. Donations are great, but not for this. I am very capable of making enough money to pursue my interests. Thanks for … Continue reading An Epiphany
The Rose
Working on Rain
When it Rains.... anxiety, fear, hopelessness, worry, angry, fatigue, guilt, trust, perception, substance abuse, stress, psychosis, family, violence, philosophy, paranoia, victim, panic, insomnia, self-blame, social skills, depression cheapens life worthlessness, stress, bi-polar, PTSD, medication, psychosis, determined victim, sensitive in an empathic way, trauma (the loss of self) reconnecting with the body is the cure, letting go, … Continue reading Working on Rain
Scar to the Poe
Mental illness contaminates the air. The choking and coughing stir fear in those rendering our care You know of this illness? I say, you do not. Stroll with me for a glimpse into this most disturbing plot.
The Way
Life has taught me that consistent quality is a good way to go. Is it Common Sense? Should be. Is it Easy to execute? No.


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Our first gig in Hollywood. Come play with us at the M Bar on Vine.
special guests - Melissa Wolfklain and Jessica Reiner Harris
Tix on sale now
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