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American rappers Danny Brown and JPEGMAFIA sat down with Rockstar Games on Twitch to play through Grand Theft Auto Online's new Diamond Casino Heist, and things didn't go as anyone had planned.
GTA Online's last major content update of 2019, the Diamond Casino Heist was introduced to players on December 5, 2019.
Brown is a known GTA Online player and fan, so having him and JPEG come to stream the newest Heist seemed like a win-win for Rockstar, until things eventually went off the rails.
The infamous @xdannyxbrownx — AKA Yung Ancestor — will be joining us on the Rockstar Games official livestream this Friday with @darkskinmanson to take on the Diamond Casino Heist. https://t.co/RIPTDJH1vh pic.twitter.com/aXdFy5s3px
— Rockstar Games (@RockstarGames) January 30, 2020
The pair's attempts at the heist repeatedly turned into a bloody mess, but their strategy was the last thing any of the viewers in chat were talking about once one of them started getting wild.
Brown made some very non-PC jokes, startling the Rockstar staff on hand and even JPEGMAFIA, who seemed taken back by his comments at a few points.
He reminded them that it was their choice to bring him on, and they should have known what they were getting into with him on the stream.
Although he definitely seemed to be more comfortable and experienced in GTA Online than JPEGMAFIA, Brown wasn't able to lead his team to the end of the new heist.
Read More: GTA Online update: New Lucky Wheel bike, 2x payouts & Twitch Prime rewards
Danny and JPEG ran out of lives and didn't manage to finish before their streaming time ran out, but things were definitely headed into dangerous territory for an official Rockstar stream.
Viewers in chat definitely thought things were cut short, and both performers seemed ready to continue trying, but whether or not Rockstar actually cut the stream short is impossible to prove or disprove.
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Travel Grants
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application deadlines to be announced


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Heart murmurs are characterized by an extra or abnormal noise when the blood flows through the heart. They can occur when the heart contracts, relaxes, or throughout the heartbeat. Heart murmurs can be present at birth or occur later in life. If you're a pediatric nurse, it's important to know the signs of the condition and how it's treated. Here's what you need to know.
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HUMBOLDT — Pickleball fans have a new place to play the fast-growing sport.
A court has been added to the multi-purpose room at Humboldt Elementary School. The court has been marked with taped lines. USD 258 officials plan to paint lines for an official court this coming summer.
About 10-12 people have been booking slots to play pickleball at the school, Darcie Croisant, with the Humboldt Recreation Commission, said. A group from Iola also has played at the school in their search for a suitable indoor site, she said.
The school began offering the venue in early February. Now that the wrestling season has ended, the multi-purpose room typically is available from 6-8 p.m. during the week and on Saturdays from 10 a.m. to 2 p.m. if no other activities are scheduled.
Pickleball clinics likely will be offered after spring break.
"We hope that will get more youth and adults interested," Croisant said.
The recreation commission also wants to build a court at Cannon Park in Humboldt's downtown.
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Humboldt school board members approved adding the court to the elementary school after discussion at a January meeting. Superintendent Kay Lewis said she thought there was quite a demand for the sport and that the activity could be good for students.
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For more information about the Humboldt school court, contact Darcie Croisant at email@example.com.
PHOTO: Humboldt Pickleball enthusiast Lyle Kern, Iola, shows the retrofitted tennis courts at Meadowbrook Park in this file photo. Humboldt has added a pickleball court to its the elementary school.
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African LTE adoption will quickly be followed by soaring IoT applications – is your network ready?
Across Africa, LTE subscriptions are surging ahead, bringing the benefits of mobile broadband access to millions of new customers each year. According to Ericsson's forecast for Sub-Saharan Africa, LTE subscriptions are expected to reach 20% of the total user base – which is itself growing rapidly, driven by new subscriptions, as well as uptake of other technologies, including WCDMA[1].
This is great news for the continent – and the situation is likely to evolve considerably, as operators extend their investments through the additional deployment of VoLTE services. Already, as Ericsson reports, more than 30 operators have launched LTE in the region, with many more expected to come. As a result, we can expect that VoLTE will swiftly follow.
This creates an interesting situation. On the one hand, the classical mix of voice, data and messaging services can be expected to thrive, with more users, more subscriptions and more devices. On the other, new, higher speed access will unlock a range of new services that differ from the core template. Such services will include a growing range of IoT and M2M applications, enabled by high speed mobile connectivity and better overall coverage. Operators need to be able to ensure that existing services perform as the user expects, while also preparing to support a host of unknown new services.
As a result, operators need to consider two key points. First, how will they obtain the service visibility they need to deliver the right level of customer experience, across a diverse network base (combining legacy and LTE technologies) that will evolve further as VoLTE is added to the mix? Second, how will they simultaneously obtain the same level of visibility for new services which may have very different performance benchmarks and requirements from those to which they are accustomed?
Inna Ott, director of marketing at Polystar, says: " IoT applications offer the promise of new revenue streams and an expanded addressable market but present new challenges. While KPIs and benchmarks for classical services, such as voice are well understood, those for new IoT services and applications may, as yet, be unknown."
IoT applications offer the promise of new revenue streams and an expanded addressable market but present new challenges. While KPIs and benchmarks for classical services, such as voice are well understood, those for new IoT services and applications may, as yet, be unknown. Some services will have minimal network demands – for example, the transfer of simple sensor measurements or location positioning from remote devices – while others, for which LTE provides the requisite infrastructure, will be more complex.
These will include new applications to address key verticals, such as remote healthcare monitoring, or will enable the delivery of extended educational programmes, for example. At the moment, we don't know what all of these services will be, but we can safely say that there will be many of them and that there will be a burst of innovation, as people both bring existing services to the region from elsewhere and also as people within the region find local solutions for their unique needs and challenges.
All of which takes us back to the second point we noted. How do you deliver and maintain the network uptime and service quality that a wide – and growing – range of IoT applications will require? Can mobile networks handle the volume of devices that may be deployed by each customer? Can operators ensure that their networks meet highly variable or even volatile quality of service demands?
So, LTE both adds to the existing network complexity while, at the same time, providing a platform for future innovation, particularly for IoT applications. In this context, it's essential that operators take the necessary steps to prepare for a flood of new traffic, from a wide range of different sources. They need to adapt, so that they can obtain the visibility of service performance necessary to ensure that they deliver the right customer experiences, whether to a person or whether for a device servicing an application. In short, they need a continuous, real-time stream of insights derived from all network data in order to assure both overall and application-level performance.
This means that there will be a wide range of internal users of such information. It's no longer sufficient to provide rich data only to network operations teams. Other departments and groups must be able to view and act on insights gathered from the network. This means that operators need systems and solution in place to both collect and then filter data in a way that is appropriate to the needs of each relevant user.
That's quite a challenge, but there are already solutions available that can meet this goal, serving both classical services, irrespective of the network on which they are delivered, as well as new and emerging IoT services. As Africa moves to embrace LTE and to embark on the IoT revolution, operators need to be sure that they have the appropriate tools in place to support both this transition as well as the next phase of network evolution. Are you ready?
[1] Ericsson Mobility Report, Sub-Saharan Africa, November 2015
This blog post was initially published on the AfricaCom/Informa Blog.
Inna Ott
Director of Marketing
Phone: +46 8 50 600 600
Email: email@example.com


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Sequoia, Blackbird rule the roost as tech funding grows despite COVID fears
The Australian technology sector scooped up $6.9 billion in funding for the 2020 financial year despite COVID-19 jitters hitting the market.
- by Cara Waters
Goldman Sachs-backed lender Capify taps into loan optimism
Goldman Sachs backed small business lender Capify has opened its books to lending again after raising $14 million from a group of high net worth individuals.
- by Cara Waters
Claims Australian firms impacted by 'rampant fraud' at German leasing giant Grenke
Australian businesses may be victims of alleged "rampant fraud" at German finance leasing giant Grenke AG according to a damning report published by anonymous online group Viceroy Research.
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Eftpos goes digital for the first time as retailers push for low-cost payments
Australia's debit card system Eftpos will begin processing digital payments for the first time in its 35-year history.
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Millions in promised tourism relief goes unspent as most WA businesses fail to qualify
Less than 20 per cent of WA's tourism businesses have been granted emergency relief, leaving almost half of $10-million promised handouts unfulfilled.
- by Aja Styles
Judo Bank's Joseph Healy warns on 'zombie firms'
Judo Bank co-founder Joseph Healy warns small and medium businesses are taking on $25 billion in unproductive debt to survive the pandemic.
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Insurers deny business insurance claims as battle begins
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Australian economy
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Economic Columnist Ross Gittins talks about his 40+ year career writing for The Sydney Morning Herald and The Age
Masked traders return to NYSE floor after shutdown
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Accounting software provider MYOB has cut 130 jobs as chief executive Greg Ellis warns of Australia's artificial economy propped up by JobKeeper and JobSeeker programs.
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Client issues mounting for Greensill as COVID-19 wreaks havoc
After a string of collapses by Greensill's corporate clients, the group is now under pressure to dump a key Australian customer, believed to be UGL.
- by Sarah Danckert


text:
Five major inherited disorders are considered risk factors for recurrent venous thrombosis: protein C, protein S, or antithrombin III deficiency, hyperhomocystinemia, and activated protein C (APC) resistance. In 1993, Dahlbäck1 noted that the addition of APC to plasma obtained from a patient with recurrent thrombosis, without any previously recognized thrombotic disorder, did not prolong the activated partial thromboplastin time as occurred when APC was added to plasma from healthy individuals. The term APC resistance was used to describe this patient. Most patients with APC resistance have a mutant factor V molecule (Leiden mutation) that resists proteolysis by APC when activated to factor Va. This resistance is the result of a specific point mutation (replacement of arginine 506 by glutamine) in the gene coding for coagulation factor V. Not all patients with APC resistance will experience thrombosis. Additional genetic defects or exogenous factors may be necessary to induce thrombosis in
Depaire-Duclos F, Gris JC, Dandurand M, Guillot B. Thrombotic Klinefelter Syndrome Associated With Factor V Leiden Mutation. Arch Dermatol. 1997;133(8):1051–1052. doi:10.1001/archderm.1997.03890440135027
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text:
Low Investment High Profit Business – Low Investment Business Ideas better than Franchises under 5K
August 22, 2016 Videos
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Week 1, 11:00 class
Week 1, 10:00 class
Week 1, 9:00 class
Ithaca Class, 4/24/16
Here are new tunes from last week:
Tamlin (harder)
and (thanks, Anne, for reminding me), a transcription of Fig for a kiss:
Ithaca Class, 4/10/16
Here's our new tune from 4/10/16:
Ithaca class 2/7
Links to some of the tunes from class today:
A new one – Tombigbee Waltz
and a few old ones –
An Dro in A minor
Beren Tanz
John Brosnan's
We also talked about learning a tune called "Dancing Bear" (different from "Beren Tanz"!) to work on playing fast tunes with lots of notes, but didn't learn much of it. I'll try to get a recording up here soon.
Ithaca class 1/10 – Ashokan Farewell
A bit late with this, but here's a basic version of Jay Ungar's "Ashokan Farewell:
Ithaca class 12/6 – The Snowy Path
Here's the tune we started learning – The Snowy Path
And links to some others that we played:
Angeline the Baker
Mairis Wedding
Swallowtail Jig
Fig for a Kiss
John Brosnan's
Orzechowski and Ball CD release
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Physical CDs will be available from Tim and Sophie in December 2015, and CD release concerts are planned for early 2016. Check Tim's website http://timballviolin.com for details, or contact email@example.com for more information.


text: Ventilation: A Breath of Fresh Air for Your Florissant Home and Indoor Air Quality Posted August 12, 2015 When it comes to whole home comfort and indoor air quality, there's nothing like breathing in fresh, clean air throughout the year. Of course, the weather in Florissant may not make that seem probable during hot and cold months, but there is an often forgotten aspect of indoor air quality that gets overlooked: ventilation. When most people think about ventilation, they typically think about opening a few windows around their home or using their screen doors. While this is still ordinary, it's not practical through the year in Florissant. That's where we can be grateful for the advancements in technology that have presented us with heating and cooling equipment that produces the same effects of having your windows or doors opened for ventilation. Today's ventilation systems run by pulling just the right amount of fresh air from outside, providing you with the perks of traditional ventilation while eliminating odors, chemicals and other pollutants from your home's indoor air. The process not only ensures you have nicer feeling air, it gets rid of stale air from your home, helping make your home's air as comfortable as it can be without wasting energy. Picking a ventilation system is fairly easy as there are two sorts of systems used: Energy Recovery Ventilators (ERVs) and Heat Recovery Ventilators (HRVs). Most of the United States, and all of Canada, are recommended to use HRVs as a result of the environments in those areas. ERVs are nearly exclusive to southern regions that have higher than normal humidity levels. Ventilation is just the beginning of things when thinking about indoor air quality. If you'd like to learn more about all that you can be doing to improve your home's indoor comfort, check out the other blogs we've written on indoor air quality. From dehumidifiers to air filtration and air purification, the pros at B & B Heating & Cooling know indoor air quality. Schedule an appointment by calling them at 314-325-7552 to take your home's air quality to another level. Back To Blog


text:
Beauty On Lockdown Week 14: Holding On To My Faith And My Moisturizer
KPB Society...
We survived another week of being on lockdown happy and hydrated. My prayer is that you are staying happy and hydrated during these uncertain times. This pandemic has definitely increased in faith and my prayer life; teaching me to pray without ceasing. I like using beauty and wellness analogies to spread love and life into the world. That's my ministry.
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text:
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text:
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Arquivos de Neuro-Psiquiatria
Print version ISSN 0004-282XOn-line version ISSN 1678-4227
Arq. Neuro-Psiquiatr. vol.64 no.4 São Paulo Dec. 2006
Central nervous system abnormalities on midline facial defects with hypertelorism detected by magnetic resonance image and computed tomography
Anomalias de sistema nervoso central em defeitos de linha média facial com hipertelorismo detectados por ressonância magnética e tomografia computadorizada
Vera Lúcia Gil-da-Silva-LopesI; Silvio David Araújo GiffoniII
Departamento de Genética Médica, Faculdade de Ciências Médicas / Universidade Estadual de Campinas, Campinas SP, Brasil (FCM/UNICAMP):
IProfessor Associado, Departamento de Genética Médica
IIDoutor em Ciências Médicas com área de concentração em Genética
The aim of this study were to describe and to compare structural central nervous system (CNS) anomalies detected by magnetic resonance image (MRI) and computed tomography (CT) in individuals affected by midline facial defects with hypertelorism (MFDH) isolated or associated with multiple congenital anomalies (MCA). The investigation protocol included dysmorphological examination, skull and facial X-rays, brain CT and/or MRI. We studied 24 individuals, 12 of them had an isolated form (Group I) and the others, MCA with unknown etiology (Group II). There was no significative difference between Group I and II and the results are presented in set. In addition to the several CNS anomalies previously described, MRI (n=18) was useful for detection of neuronal migration errors. These data suggested that structural CNS anomalies and MFDH seem to have an intrinsic embryological relationship, which should be taken in account during the clinical follow-up.
Key words: frontonasal dysplasia, hypertelorism, midline, craniofacial abnormalities, facial clefts, CNS abnormalities, magnetic resonance image.
Este estudo objetivou descrever e comparar as anomalias estruturais do sistema nervoso central (SNC) detectadas por meio de ressonância magnética (RM) e tomografia computadorizada (TC) de crânio em indivíduos com defeitos de linha média facial com hipertelorismo (DLMFH) isolados ou associados a anomalias congênitas múltiplas (ACM). O protocolo de investigação incluiu exame dismorfológico, RX de crânio e face, CT e RM de crânio. Foram estudados 24 indivíduos, sendo que 12 apresentavam a forma isolada (Grupo I) e os demais, DLMFH com ACM de etiologia não esclarecida (Grupo II). Não houve diferença entre os dois grupos e os resultados foram agrupados. Além de várias anomalias de SNC já descritas, a RM foi útil para detecção de erros de migração neuronal. Os dados sugerem que as alterações estruturais de SNC e os DLMFH têm relação embriológica, o que deve ser levado em conta durante o seguimento clínico.
Palavras-chave: displasia frontonasal, hipertelorismo, linha média, malformações craniofaciais, fendas faciais, malformações do SNC, ressonância magnética.
Midline facial defects with hypertelorism (MFDH) is a rare group of disorders characterized by ocular hypertelorism and anomalies of frontonasal process. Its isolated form is commonly called frontonasal dysplasia and it is also detected in several conditions of multiple congenital anomalies (MCA)1-3. Its pathogenesis is related to a failure during the development of the nasal capsula4,5. Differential diagnosis should be done from some conditions which could lead to a similar appearance, such as frontal lipoma and encephalocele5. Several structural abnormalities of central nervous system (CNS) are often described in this group, such as encephalocele, myelomeningocele, Chiaris malformation and hydrocephalus6. Corpus callosum anomalies are reported by several authors3,7-10.
Some important points should be mentioned about the MFDH and CNS anomalies. One of them is the rarity and heterogeneity of this condition, which led to isolated descriptions by different specialties and with different emphasis. Another one is the advance of neurorradiology techniques that now allow an excellent evaluation of CNS. The use of magnetic resonance image (MRI) searching CNS anomalies in a large group of individuals with MFDH has not been reported before.
In this article, we describe the neurorradiological data from 24 patients with MFDH.
The casuistry was composed by 24 individuals (8 male and 16 female) affected by MFDH10. All of them were previously evaluated by the same clinical geneticist at Hospital das Clínicas HC/ UNICAMP (Campinas, SP, Brasil). They were selected based upon minimum inclusion criteria, which were ocular hypertelorism and frontonasal process anomalies. Twelve individuals presented an isolated form (Group I) and the others, facial findings were part of a multiple congenital anomalies condition with unknown etiology (MCA) (Group II). The average age was 12.57 years.
The investigation protocol included dysmorphological evaluation, skull and facial X-rays, computed tomography (CT) of brain and magnetic resonance image. Six individuals who had metallic clips on their faces were evaluated just by CT.
Brain CT was performed with parallel slices to the inferior orbitomeatal line with 3 mm of thickness and 5 mm of space on the posterior fossa. On the supratentorial fossa, the slices had 10mm of thickness and space from vertex of transversalis axis.
CNS MRI was performed without contrast at 2.0 T. The sequence was: Axial FSE double eco T2; TE=16/128. TR of 4600, 6 mm of thickness and 2% of space. Axial FSE double eco DP, TE=16/128. TR=4600, 6 mm of thickness and 2% of space. Sagittal SE T1; TE=10. TR=550, 4 mm of thickness and space of 0%. Axial SE T1; TE=10. TR=550, 6 mm of thickness and 2% of space. Coronal SE T1; TE=10. TR=550, 6 mm of thickness and 2% of space. Axial flair inverse recover TE=90 on CSF. TR=8100, TI=2200, 6 mm of thickness and 2% of space. When necessary, CT scan and MRI were performed with anesthesia, according to the American College of Emergency Physicians. The statistics evaluation was performed by SAS System for Windows (statistical analysis system), version 8.02. It was used Fischer 's exact test (FET). The rejection level was fixed at 5%11,12.
This study was approved by the Ethics Committee of the University Hospital / UNICAMP (n.057/99) and all individuals consented for their inclusion.
Mainly clinical features of Group II are described on Table 1. A considerable heterogeneity of CNS anomalies was detected (Figs 1A and 1B; 2 and 3). Comparing the investigation of Groups I and II, no statistical difference was found and the results are described on Table 2.
Considering the rarity of the condition and the description by different specialties, the evaluation of CNS defects in a significant casuistry with MRI had not been performed before. Until now, the most part of information about the neurological anomalies in MFDH was obtained using CT3,7-9. These studies showed a large range of CNS anomalies, especially of the corpus callosum, such as lipoma, calcification, and dysgenesis. Some other anomalies were also mentioned, such as encephalic asymmetry and encephalocele. In this casuistry, the main defects detected by skull and facial X-rays were hyperteleorbitism (24/24), anterior cranium bifidum (8/24) and frontal osseous failure (4/24). These findings are similar to those previously described.
Guion-Almeida9, reviewing 27 patients from the literature and personal cases, reported anterior cranium bifidum in 12 individuals. Gil-da-Silva-Lopes and Maciel-Guerra3, evaluating brain CT of 29 personal patients with MFDH, including isolated form and those with multiple congenital anomalies with unknown etiology, detected anterior cranium bifidum in 6 individuals and frontal osseous failure in 4.
Brain CT in this study showed anomalies of corpus callosum (8/21) and several defects, such as osseous (7/21), ventricular (3/21), cortical (2/21), frontal lobe atrophies (2/21) and encephaloceles (3/21). Lipoma of corpus callosum, a usual feature reported, was detected in just one of our patients. Corpus callosum is the main anomalous structure described in this condition. Fontaine et al.13 described 3 isolated cases with MFDH and corpus callosum agenesis. In a clinical follow-up of 8 patients, Pascual-Castroviejo et al.7 detected lipoma and calcification of faux in all of them and hypoplasia of the corpus callosum in brain CT. Guion-Almeida9 detected 8/100 patients with corpus callosum agenesis. In an extensive review of the literature, and also adding personal cases, Gil-da-Silva-Lopes and Maciel-Guerra3 observed agenesis of this structure in 5/31 individuals and dysgenesis, in 4/31. These authors also described encephaloceles, ventricular anomalies, cortical atrophy and CNS calcifications.
Naidich et al.8 reported CNS findings of 11 individuals with MFDH detected, by computed CT of the crania in 10 and MRI in 1 of them. In this study, 5 patients with lipoma of the corpus callosum and 1 with calcification of faux and interhemispheric lipoma were observed. Gil-da-Silva-Lopes and Maciel-Guerra3 detected lipoma of corpus callosum in (2/31) patients.
Two of our patients had errors of migration detected by CT scan. This number had an increase when we used MRI (7/18). This kind of investigation also evidenced corpus callosum anomalies (agenesis/dysgenesis) in 8/18 individuals, ventricular anomalies (8/18) and cerebellar hypoplasia in 3/18.
Cortical anomalies have been described in a group of 10 patients with frontonasal dysplasia, corpus callosum agenesis and mental retardation. In this group, MRI was performed in 8 patients (7M:1F). All the males had periventricular nodular heterotopia (PNH)14. This author suggested that it would be an X-linked defect. PNH was also described by Dobyns et al.15, in 3 males affected by cerebellar hypoplasia, corpus callosum dysplasia, mental retardation and syndactyly; one of them had distal Xq duplication. Two other unrelated males affected by PNH and mental retardation were described by Guerrini and Dobbyns16. Cerebellar hypoplasia detected in 3 individuals of this casuistry, reinforces the clinical suggestion of involvement of this structure in MFDH17.
The presence of several anatomic alterations of the CNS was similar in isolated cases and in MCA conditions. Considering the rarity of this disorder and the delineation of this study, this casuistry seems to be representative. Spite of it, it may be not enough for a conclusion among isolated and MCA forms of MFDH. In fact, these results could indicate a common embryologic damage or a sequence of events secondarily to failure during the development of nasal capsule, as well. Thus, structural CNS anomalies and MFDH seem to have an intrinsic embryological relationship. These aspects should be taken into account during the clinical follow-up.
Finally, the use of MRI in this group of congenital defects would contribute for better characterization of CNS anatomical subtleness, such as migration errors.
Acknowledgements - The authors would thank the exceptional cooperation of the patients and their families, Hospital de Reabilitação Craniofacial (HRAC - "Centrinho" - USP) and Sociedade Brasileira de Pesquisa e Reabilitação de Anomalias Craniofaciais (SOBRAPAR, Campinas, SP). We also thanks Dr. Maria Leine Guion-Almeida (HRAC - "Centrinho" - USP) for her clinical opinion in some cases, and Drs. Vanda Maria Gimenes Gonçalves and Verônica A. Zamardi, from Departments of Neurology and Radiology (FCM/UNICAMP) for productive discussions.
1. Sedano HO, Cohen MM Jr, Jirasek J, Gorlin RJ. Frontonasal dysplasia. J Pediatr 1970;76:906-913. [ Links ]
2. Sedano HO, Gorlin RJ. Frontonasal malformation as a field defect and in syndromic associations. Oral Surg 1988;65:704-710. [ Links ]
3. Gil-da-Silva-Lopes VL, Maciel-Guerra AT. A clinical study of 31 individuals with midline facial defects with hypertelorism (MFDH) and a guideline for follow-up. Clinn Dysmorphol J (2006, submitted) [ Links ]
4. Cohen Jr MM, Sedano HO, Gorlin RJ, Jirasek JE. Frontonasal dysplasia (median cleft face syndrome): comments on etiology and pathogenesis. Birth Defects. OAS 1971;7:117-119. [ Links ]
5. Cohen MM Jr. Malformations of the craniofacial region: evolutionary, embryonic, genetic and clinical perspectives. Am J Med Genet (Sem Med Genet) 2002;115:245-268. [ Links ]
6. DeMyer W. The median cleft face syndrome. Differential diagnosis of cranium bifidum occultum, hypertelorism, and median cleft nose, lip, and palate. Neurology 1967;17:961- 971. [ Links ]
7. Pascual-Castroviejo I, Pascual-Pascual SI, Pérez-Higueras A. Fronto-nasal dysplasia and lipoma of the corpus callosum. Eur J Pediatr 1985; 144:66-71. [ Links ]
8. Naidich TP, Osborn RE, Bauer B, Naidich MJ. Median cleft face syndrome: MRI and CT data from 11 children. J Comput Assist Tomogr 1988;12:57-64. [ Links ]
9. Guion-Almeida ML. Estudo genético clínico da disostose frontonasal. Dissertação. Bauru, 1991. [ Links ]
10. Giffoni SDA, Gonçalves VMG, Zanardi VA, Gil da Silva Lopes VL. Angular analysis of corpus callosum in 18 patients with frontonasal dysplasia. Arq Neuropsiquiatr 2004;62:195-198. [ Links ]
11. Conover, WJ. Practical nonparametric statistics. New York: John Wiley & Sons, 1971. [ Links ]
12. Fleiss JL. Statistical methods for rates and proportions. New York: John Wiley and Sons, 2nd ed., 1981. [ Links ]
13. Fontaine G, Walbaum R, Poupard B, et al. La dysplasie fronto-nasale (a propos de quatre observations). J Génét Hum 1983;31:351-365. [ Links ]
14. Guion-Almeida ML. Defeito de linha média facial e hipertelorismo. Tese. Campinas, 2000. [ Links ]
15. Dobyns WB, Guerrini R, Czapansky-Beilman DK, et al. Bilateral periventricular nodular heterotopia with mental retardation and syndactyly in boys: a new X-linked mental retardation syndrome. Neurology 1997;49:1042-1047. [ Links ]
16. Guerrini R, Dobyns WB. Bilateral periventricular nodular heterotopia with mental retardation and frontonasal malformation. Neurology 1998;51:499-503. [ Links ]
17. Giffoni SDA, Gonçalves VMG, Zanardi VA, Gil-da-Silva-Lopes VL. Cerebellar involvement in midline facial defects with ocular hypertelorism. Cleft Palate Craniofac-J 2005;43:466-470. [ Links ]
Received 24 February 2006, received in final form 21 June 2006. Accepted 27 July 2006.
Dra. Vera Lúcia Gil-da-Silva-Lopes - Departamento de Genética Médica - FCM / UNICAMP - Caixa Postal 6111 - 13084-971 Campinas SP - Brasil. E-mail: email@example.com


text:
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Connectivity: The VPN tends to connect very quickly and is quite stable once connected, even in countries like China.
Shadowsocks: Even though this is in the trial phase, Surfshark is one of the few VPN providers that offers the possibility of using Shadowsocks. This is one of the most effective systems for getting around the restrictions imposed by the Great Firewall of China. However, we only recommend using this system in special cases that involve privacy risks.
Simultaneous connections: Surfshark theoretically offers unlimited simultaneous connections (we haven't tested this). While on certain occasions this can be very useful, in the majority of cases, the 5 connections offered by the majority of providers tend to be more than enough for personal use.
What we like the least about Surfshark VPN
Streaming in China: The ideal configuration for connecting the VPN in China doesn't usually allow access to the most popular streaming platforms. While the VPN can be adjusted to allow access to these platforms, its speed and/or connectivity tend to be problematic.
Speed in China: Even though it offers good connectivity and an acceptable speed in China, it is still far from attaining the speed offered by other providers that are popular in the country.
Private IP addresses: It is unfortunate that Surfshark doesn't offer the possibility of purchasing exclusive IP addresses. If it offered them, it would definitely be one of the most complete VPNs on the market.
How much does it cost and which option should I choose?
Currently, Surfshark offers three types of plans:
Monthly plan: 9.89 EUR or 11.95 USD per month.
Annual plan: 59.88 EUR or 71.88 USD (4.99 EUR or 5.99 USD per month).
Biannual plan: 42.95 EUR or 47.76 USD (1.79 EUR or 1.99 USD per month).
The biannual plan is without a doubt the only one that makes sense. The monthly plan doesn't save you any money compared to other VPNs with better services. On the other hand, if you take into account the special offer, purchasing 12 months is more expensive than 24 months.
Recommended uses of Surfshark
Surfshark is a VPN with high-quality services at a very low price, and is a good option for people looking for the best quality/price ratio.
Because of its low price, it is also an ideal VPN to use as a backup for the
VPN that you usually use in China. Surfshark offers good connectivity in China, decent speeds and the possibility of using Shadowsocks. Because of that, if your main VPN is temporarily blocked, as has been happening recently, you have an alternative VPN to be able to continue enjoying unrestricted internet access.
I don't recommend using it as your primary VPN in China, as there are other VPNs with better services, and its streaming configuration is too slow in China.


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Get to Whistler by Air
Consistently rated one of the top airports in the world, Vancouver International Airport (YVR) is serviced by 55 airlines and 125 non-stop destinations in Canada, the United States and around the world. Vancouver International Airport sits 25 minutes from downtown Vancouver and roughly two hours from Whistler along Highway 99, a scenic road also known as the Sea to Sky Highway. For more information on cities that offer non-stop flights and airlines servicing YVR click here.
Getting to Vancouver
|Approximate Flying Time
|Toronto (YYZ)
|5 Hours
|San Francisco (SFO)
|2 Hours
|Los Angeles (LAX)
|3 Hours
|Denver (DEN)
|3 Hours
|Chicago (ORD)
|5.5 Hours
|New York (LGA, JFK & EWR)
|6 Hours
|London, England (LHR)
|10 Hours
|Sydney, Australia (SYD)
|15 Hours
For more information on cities that offer non-stop flights and airlines servicing YVR click here.
Getting to Whistler
- Travel Time: approximately two hours
- Distance: approximately 120 kilometres (75 miles)
- Open Google Directions
Rent a Car
Rent a car from Vancouver or Seattle Airport.
Most car rentals include unlimited mileage, ski racks and child seats upon request. Insider tip: avoid paying hotel parking with one-way car rentals through Avis.
Once in Whistler, you won't need a car. The village is pedestrian-friendly, has great local bus service and most hotels are located within walking distance to the lifts.
Take a Shuttle
Make life easy by taking a Pacific Coach Lines shuttle from Vancouver to Whistler.
The shuttle has pick-up locations at both Vancouver Airport and several Downtown Vancouver Hotels. Take advantage of optimum convenience with drop-off right at your accommodations in Whistler.
Hire a Limousine
Make your way from Vancouver International or Sea-Tac Airport to Whistler in the comfort of a stretch limo, excursion SUV, luxury van or luxury minibus.
Helicopter Transfers
Getting to Whistler from Seattle
- Save money by flying into Seattle. Seattle-Tacoma International Airport (Sea-Tac) has more domestic U.S. flights than Vancouver International Airport, which translates to more competition and better flight deals.
- Discount carriers such as Frontier, Southwest and Virgin Airlines fly direct to Seattle, but not Vancouver.
- Whistler is a 4.5 to 5-hour scenic drive from Sea-Tac Airport and an only 2.5-hour drive from Bellingham Airport.
Seattle to Vancouver
Relax, enjoy the sightseeing, and let someone else do the driving. Take Quick Shuttle from Sea-Tac Airport to Vancouver International Airport or downtown Vancouver.
Then connect with Pacific Coach Lines to travel from Vancouver to Whistler along the spectacular Sea-to-Sky highway. For charter bus options please contact our groups department.
Canada/U.S. Border
The Canadian/U.S. border station at Peace Arch underwent big improvements during the 2010 Winter Olympic and Paralympic Games.
This helps with traffic flow, processing time and now the drive only takes about three hours from the border to Whistler.
You Might Also like
Cyber Week Sale
Winter Operations
Check out winter 2020.21 opening dates and hours of operation.
We're passionate about the outdoors and our mountain communities, and we're committed to protecting these special places and everyone who comes to experience them.
Need help booking?
We are experiencing heavy call, email, and social media inquiries. Thanks so much for your patience while we work to respond to all of our guests over the coming days and weeks. For assistance with pass reservations, please use Live Chat found on my account and reservation pages on EpicPass.com to help with any questions you have.


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You're reluctant to trust your emotions rate backpage escorts Waterville to your inability to restrain them. The pain is so good, you casual sex right niw to protect yourself by deadening your own emotions, from feeling a lot. You may feel an emotional" numbness. " Many men and women experience a little fantasizing during grief. You will fantasize that you visit your former love spouse or that you hear his or her voice. You might fantasize that part of your own body is missing if your heart were eliminated, representing the loss of the other individual. This fantasizing may be terrifying if you don't recognize it as a normal part of grief.
Currently don't get me incorrect, I'm not informing you to attempt and fool people right into assumingyou're far better looking than you are. Yetyou're going to obtain some really uncomplimentary photos occasionally and you don't want the one picture that you obtained of you holding the eagle to make you look unsightly and also not have any others to select from.
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Pretending to Be Someone we all have met with. Whether they're currently trying to act cooler or richer than they are, everybody has a small dislike for these people since they aren't genuine.
Active woman in search of a physically active, thoughtful financially secured and considerate. This ad asks something but what. A few more words in this sentence could have clued us as to just exactly what it is that must fulfill with her demands.
Make it a habit to casually go out a few days every week and go and meet new women. Go speak with them without expecting or wanting anything out of the interaction or them. Only strike up a conversation because you wanted someone to speak to and she seemed intriguing.
It is the exact same thing with getting rejected by a beautiful woman. The limbic system in the brain can learn at any point in your lifetime, and it may learn when you go up to them, that you shouldn't be afraid of women. Your anxiety disintegrates, piece by piece, to the stage when you participate a gorgeous woman that you are in full control. Guys thatare'naturally' good with women have these experiences on and eventually become very at ease around women that are lovely in the young age. You can attain the same level of success with women by putting yourself through a process that is similar.
I hope I'm not painting a picture and suggesting once they meet you that you don't have any shot with women that do not answer with a resounding Yes. But bear in mind that being in the grey area is not a place to be. You have to work twice as hard to get half as far with these girls.
Dating japanese escorts backpage Bromont QC to instability will result in the person's heartbreakyou're dating. As soon as they receive a call and recognize they're being used for financial reliability, they'll leave you more shaky than you were before going into the relationship. For dating because you relied upon them they will no longer feed your self or evil intentions. You are left unprepared regarding life and the many facets of fact.
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Aside from finding PG fun to talk to and intriguing, I was also drawn to him, and he to me. The chemistry was definitely there since we leant over to kiss each other. In fact, it felt as though we could not keep our hands off each other.
Family of Origin Influences Your family of origin is the family in which you grew up. Your parents, siblings, grandparents, aunts, and uncles- - all were important influences shaping your view of" how a Bromont QC craigslist escorts backpage ought to be. " Most were likely healthy; some weren't.
That euphoric sensation you get when you are around or are thinking about your enjoyed one is pure hormones taking control of your body and mind. They claim love is one of the most beautiful thing. It is 2spirits coming together and voluntarily linking right into one. From a physical standpoint, when two individuals remain in love, the adrenaline and phenyl ethylamine nerve transmitters take place overdrive triggering us to be in a continuous state of bliss and mindless bliss. Researchers claim that dropping in love cultivates an organic state in our bodies that gives us a high, comparable to that of getting on cocaine! However neglect the science of it all, falling in Bromont Québec backpage escorts mmf is easy. We do a bit of it every single time we see a person with the physical attributes that we consider desirable that is why most individuals are absolutely crazy with numerous movie celebrities. It is the actual dropping in love and also resolving into a caring relationship that requires work as well as complete consideration. So, how exactly do you understand if what you have is the genuine thing? Just how Do You Know This Is The Genuine Point? With today's fickle spirits, real love is remarkably not so challenging to find. It is however, really mired in complication. If you asked any teenager who has a companion currently, they will certainly tell you that they have actually found their real love, despite the fact that data recommend that this is simply a passing fling, for teens hardly ever locate just among their' true likes'. From an emotional stand factor, true love can be specified as entirely selfless. The someone you would happily lay down your life for. This is the individual that makes your heart satan fuck buddy as well as beat faster, ever so slightly when they are about. The someone, you can not religious online dating sites to see at the end of the day, heck, the a single person that only the idea of seeing them later obtains you via most days. What, with the ever significantly dreadful bosses and unstable financial times, it's a marvel you haven't Bromont QC real backpage escorts your mind.
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With Mindfulness, you'll discover the remarkable truth behind meditation and being within your life. Drawing on historical knowledge Olivia will show you how to calm your mind that is racing within minutes. You'll be thrilled by how easy these practices are and by your life will soon change.
It's normal to feel totally enamored. The Bromont fills your every thought and becomes the most important individual in your lifetime. You might feel it is expected that you send that person money if they ask for it and appropriate.
The Woman With A Man Program is tough but honest. The girl with an strategy to meet Bromont Québec latina escorts backpage worthy needs to safeguard heart and her time from these applicants who aren't casualties of casual sex Bromont. There are plenty of fish in the sea; toss back the little, stupid, slimy ones.
Get to know the other person before meeting them offline that's the reason why dating sites have the messaging and chat methods setup. They allow you to create the first contacts.
MAW's should want female friendships, since it's girls who know the female experience and can necessarily offer much better advice and safeguards against the vicissitudes of the female life. Since there isn't an underlying Darwinian struggle playing out in the same way as is present in relationships A female- female connection can be a true peer relationship. There is an inequality to male- female relationships, in that alternatives for backpage escorts Bromont individual is always going to need more in one manner or another, from another. The fundamental reality of male- female connections is that women and men were created to replicate, and as such, there'll always be a reproductive gun inside the room. Girls are more acutely aware of this( or at least ought to be) , since they're sexualized from a younger age as a result of their earlier pubertal growth and neotenous good looks. They just have more experience playing with this match, and so relationships serve as a defense against male behaviour.
Framing a statement to your spouse together with the negative phrase, " I do not want, " is putting them on the defensive before you finish uttering the sentence. It contributes with negativity instead of clarity.
In my humble opinion if you are not concerned with relating to anyone, then spare yourself and the individual the unnecessary annoyance. Kindly do not pursue a relationship untilyou're prepared.
Get Her Number the moment you start talking to her, try to get some common points. Perhaps you like the same artist, prefer a similar cuisine, talk about the love for a hobby or something else. As soon as you find this tidbit of Bromont QC backpage bare escorts, hold onto it. You can casually bring this up at a subsequent stage in the conversation and use it to receive her number. As an example, if she lets you know that she likes Mexican food and you have a perfect location in mind for her, then it is possible to say something along the lines of, " I know this quaint little Mexican food joint that I'm certain that you would like. Consequently, if you give me your number, I will text you the speech! " This is not merely a smooth way to ask for her number, but it's non- threatening, too.
Unicorn- - In Polyamory, this really is really a bi sexual person( usually female) who's willing to join a couple, sexually date, who does not need anything cause problems for the original couple.
But when I say" very close friends" I am referring to another site like backpage escorts Bromont whom I've known, in some instances, more than half of my life. These are people that I adore. I refer to them as sisters and my brothers. They're, by all accounts, more of a family to me than my" real" household has been. I go to them with, and for, everything from information that is joyful to advice, and they have always come through for me.


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Current Location: Home>>Products
Technical requirements for clear aluminum mirror
1. The reflective aluminum coating shall be applied to the float glass in physical process
2. Do not need to use copper layer to protect the aluminum layer, so the aluminum mirror is copper-free.
3. Two coats of paint are applied on the top of aluminum layer, a base coating of paint with anti-corrosion effects and a covering coating of paint for protection against factors of mechanical stress.
Thickness: 2mm, 3mm, 4mm, 5mm
Standard Sizes: 1600x2200mm, 1830x2440mm, 2134x3300mm, 2134x3660mm
We can also supply customized sizes according to customers' requirement.
We can also supply edge polished mirror according to customers' demand.
The edges can be: polished flat edge, round edge, beveled edge.
Also we can drill holes on mirror for installation.
The same with silver mirror, we can also cut the aluminum mirror into small sizes according to orders, and use beveling polishing machine to polish the beveled edges, then put the mirror into washing machine to wash clean, and then we can pack them by wooden crates.
Previous: ALUMINUM MIRROR WITH SAFETY FILM
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Django: It is an open-source Python-based web framework that allows you to create web applications. Django was created by the Django program establishment within the year 2005 and planned by Adrian Holovaty and Simon Willison. The most includes of Django is the High-level python web framework as this system gives the perfect way to plan the application. It is based on the guideline of don't rehash yourself. Django put at the most noteworthy level category among the different python system for creating web applications or websites. Django has extraordinary highlights and focal points for making modern web applications.
As a designer should take after the rules or way to actualize the extend in Django, there's comparatively less flexibility compared to the low-level system but the application made will be flawless and clean. Django primarily takes after the plan design named Model Template View (MTV) plan design. It is additionally comparative to the MVC system but for the format thing. Like MVC, MTV has to the information get to layer in Model. The demonstration handles the method of collaboration, relating the information or approving the information. The layout layer is alluded to as an introduction layer, which handles what ought to be shown on the internet page or application. The see is the trade layer because it gets to the models specifically and shows a suitable layout.
Difference Between Django and Node.js
|It is an open source Python-based web framework to design web application.
|It is an open source and JS runtime environment to develop web application.
|Django is programmed in Python.
|Node.js is written in C, C++, and JavaScript.
|Django is less scalable.
|Node.js is more scalable than django.
|Django follows Model template View architecture.
|Node.js follows event-driven programming.
|Django is more complex than node.js.
|Node.js is less complex than Django.
|It is modern and behind Node.js in utilization.
|It is utilized broadly in numerous nations and ahead comparatively.
|Its official website is https://www.djangoproject.com
|Its official website is https://nodejs.org
Attention geek! Strengthen your foundations with the Python Programming Foundation Course and learn the basics.
To begin with, your interview preparations Enhance your Data Structures concepts with the Python DS Course.
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A DJ spun George Clinton's funk classic "Atomic Dog" as Bruno took center stage at Anaheim's La Palma Dog Park on Sunday afternoon.
Cameras flashed, TV news crews rigged their video cameras, dogs and owners clamored to get a glimpse of the 9-year-old German shepherd.
They were there to honor the dog who has become a local celebrity after surviving a gunshot through the jaw in March 2014. On Sunday, the city unveiled a $25,000 bronze statue, inspired by Bruno and made to honor all police dogs past and present.
The statue was created by Northern California artist Susan Bahary. She's also creating another statue, this one for the city's upcoming Olive Hills dog park.
"It's mind-blowing," said Cheryl Timmons, president of the Friends of Anaheim Police Canine Association. "When I first saw it, I was like, 'Oh my gosh, it's absolutely incredible.' She got the police badge, the look in the eye."
The Anaheim Police Department has had 23 police dogs since 1981 and had a record of no major incidents until Bruno's two years ago, Timmons said. The shepherd has since retired.
That day in March, Bruno was sent out with handler RJ Young to respond to a call of a suspect firing on probation officers who had gone to do a check. Bruno helped locate the suspect, who was hiding in a trash can.
When the K-9 lifted the lid of the can with his nose, the suspect shot the dog in the jaw.
The bullet shattered Bruno's jaw and pierced his lung, lodging near his heart. He had several jaw surgeries and a lung was removed.
The bullet, a symbol of his sacrifice, remains in his chest.
On Sunday, Bruno appeared as healthy as ever, even though he's nearing 70 in human years.
About 200 people showed up – with their own pups – to show their support for the department's K-9s.
"I support him all the way," said Carol Rhodes-Rice, who has lived in Anaheim nearly 60 years. She was wearing a Bruno T-shirt and had her German shepherd Skyy in tow.
"They're the most valuable asset we have," she said. "They're fearless, completely devoted. … God help anyone who hurts their human."
Tara Harden of Upland took the day off from working at the Los Angeles County Sheriff's Department to watch the unveiling. She had her maltipoos Bay Nicole and Sky Michelle groomed and dressed in Batgirl and Wonderwoman outfits, respectively.
"I'm an animal lover anyway, but when I heard he was shot … it was kind of close to home," she said, noting that she's friends with K-9 handlers. "I love what they do."
When Bruno was brought out near the life-size bronze statue, the six other police dogs present started barking – apparently not prompted.
"It's as if they were clapping," said CJ Eastman, a Fullerton resident.
Bruno spends his retirement at Young's home, where he chases the handler's kids around. Young said the dog has "long, lazy days" with "lots of naps."
"It's a good life," he said.
Fundraising is going on to pay the artist. About $7,000 is needed. Donations can be made at kashfork9s.com.
Contact the writer: email@example.com or 714-796-6910


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IWG, the world's leading flexible workspace provider, has launched a new franchise scheme in Romania. The new programme allows Romanian franchise operators to enter the booming workspace industry for the first time ever, and in turn help IWG expand its global network.
Flexible workspace, sometimes known as coworking, has become a high-growth industry in recent years. The term refers to office space, meeting rooms and coworking areas that can be rented by individual workers or companies for a temporary period of time, from one hour to several years. The industry is estimated to be growing by 24% each year. By 2020, 50% of all workers will be remote most of the time. In 2022, the global mobile workforce will be 1.87 billion people.This is why global real estate giant JLL estimates that up to 30% of corporate real estate could be flexible workspace by 2030.
"Three in ten buildings on every high street around the world could offer a new franchise opportunity in the coming years. The serviced office market is one of the most exciting growth markets in the world, and the next frontier for franchise operators. We are excited to partner with new franchise operators to bring the many benefits of flexible working to more people and businesses across Romania," said Arpad Szanto, Network Development Director SEE.
According to a recent IWG study, approximately 60% of Romanian employees work remotely at least a day a week and over 80% of companies consider that a flexible workspace would have a direct impact on business growth (91%), profit maximization and ongoing competitiveness (87%), that it would offer them the possibility to extend their business to new markets, to recruit and retain talent within the organization (84%). A number of 200 respondents from Romania participated in the study, employers and employees alike.
With brands like Regus and Spaces, IWG is the global operator of leading workspace providers with a network of over 3,300 centers in more than 1,100 cities and 120 countries. IWG now wants to accelerate its global growth with franchise partners worldwide.
"Imagine being given the chance to work with previously successful franchise industries such as restaurants or gyms at the beginning of their growth explosions. A similar or even larger opportunity awaits in the serviced office market. It's an opportunity to diversify away from traditional franchise industries, and benefit from strong cash returns and significant returns on investment," the Network Development Director SEE added.