text:
|DIY Audio Projects Forum
|HIFI conditioning?
|Page 1 of 1
|M. Gregg [ 18 Sep 2019, 10:34 ]
|Post subject:
|HIFI conditioning?
Has anyone,
had any experience with HIFI conditioning?
NB these tracks are very loud so if you try anything keep the volume LOW!
If your wondering what I mean its things like Cascade sound tracks.
The idea is supposed to be run the sound track through the system and "burn in" things like capacitors etc.
Now I am very sceptical about this kind of thing and I wouldn't run it through transducers or speakers for fear of damage.
NB I have no connection to cascade etc<<
I was looking at burning in some black gates and other than just running music through the system I guess it doesn't matter what it is as long as it drives the system.
My thoughts are along the lines if the main amp is turned off you could drive a pre-amp close to clipping for a short time driving all components to operating potential/frequency.
Is it a pointless excercise?
M. Gregg
|gofar99 [ 20 Sep 2019, 11:28 ]
|Post subject:
|Re: HIFI conditioning?
Hi , IMO generally yes. Mechanical components like speakers and phono cartridges yes. It usually does no harm and I generally just use the gear as it was intended. I think it is more a matter of your ears becoming adjusted to the components than them changing much. Others disagree. Like I said it does no harm.
With old NOS electrolytics some time is required for them to reform their properties though.
Good listening
|ILoveHiFi [ 20 Sep 2019, 16:03 ]
|Post subject:
|Re: HIFI conditioning?
With low to medium high quality amps theres little to zero point in anything burning in cause the changes are so small and you can't hear it
With highest end amps you can hear the burn in effect on everything then you can start thinking more more burn in
Depends on amplifier design, some amps can take large input voltage
Some cannot and you will cook it.
Clipping is safe but also depends on amp design.
To burn in black gates, what you want is to have long power on time.
Dumping mussic accros it helps, but you also need long power on time.
Also don't forgett to have a proper rated fuse so if anything gives up while your away things won't go on fire.
Don't need any speaker connections for capacior and burn in
Can also have the capacitor burnt in using a burn in rig then install the amp
|M. Gregg [ 20 Sep 2019, 16:46 ]
|Post subject:
|Re: HIFI conditioning?
I ran Cascade via iTunes to the pre-amp for two hours.
When I changed over to music is sounded terrible very loud high frequency detail almost shrill, I thought what's happened
So I just kept playing music and over about an hour it changed or so I thought.
The mid bass went deeper and the sound stage opened up then everything seemed to get a warmer sound but clear.
Strange perhaps its just me, so I will try it again and hear the difference (if any).
NB the equipment has been playing music for 7 hours continuous now and I didn't realise the time had gone.
M. Gregg
|M. Gregg [ 21 Sep 2019, 11:28 ]
|Post subject:
|Re: HIFI conditioning?
Just looking at IsoTek,
I have no connection.
Someone also suggested rainfall as another there are plenty of examples on youtube.
However I don't know how that would cover the frequencies.
M. Gregg
|M. Gregg [ 22 Sep 2019, 05:21 ]
|Post subject:
|Re: HIFI conditioning?
I ran CASCADE through the system again for a couple of hours.
There is a marked difference it is now warm sounding but again the high frequencies seemed louder "again".
The soundstage has opened up.
The soundstage was very strange at first power on so I googled other people experiences with Black Gate.
Someone said it sounds like the soundstage has been compressed in the middle of the speakers like a V and pushed right to the back.
This was my initial impression and its now opened right up. Very strange of course of no consequence now due to black gate being as rare as Rocking horse poo.
Its interesting for me to hear the depth of sound even to what sounds like Sub-bass not always welcome but interesting.
Now some of this is obviously the natural reforming of the caps, but its interesting none the less.
Having used Kaisei in the past and its my normal go to capacitor, I would probably use the non-polarised version.
There was a much quicker time to settle in the circuit.
I tried the IsoTek short play on youtube and after the system sounded warm, however there was not the increase in loudness that seemed to follow Cascade and the HF were not so clear (or so it seemed).NB cascade is a free download. But be very careful if you use it I wouldn't put it through headphones or speakers. But whatever floats your boat
For interest the Polarised version of the Kaisei is not so warm sounding. Its not the same by any stretch of the imagination but think:
Non-Polar = warm mid tones.
Polar = brighter sound.
But both have good detail and clarity.
Just my thoughts.
M. Gregg
|gofar99 [ 24 Sep 2019, 20:50 ]
|Post subject:
|Re: HIFI conditioning?
Hi, My go to electrolytic is Silmic II. Pretty easy to get good values and they seem to need little burn in. Then too most of my designs don't use electrolytic couplers or even cathode bypass ones so it is not a huge concern to me.
Good listening
|M. Gregg [ 25 Sep 2019, 08:52 ]
|Post subject:
|Re: HIFI conditioning?
gofar99 wrote:
Hi, My go to electrolytic is Silmic II. Pretty easy to get good values and they seem to need little burn in. Then too most of my designs don't use electrolytic couplers or even cathode bypass ones so it is not a huge concern to me.
Good listening
Hi Bruce,
I used to use Silmic ll and tried lots of different Electrolytic Cerafine, Muse etc in the cathode bypass function.
However after trying the Kaisei I wouldn't go back. They are a bit stark at first sort of like a frame of the sound not harsh just like to much space everywhere in the soundstage but loads of detail. Then the sound fills in over a week quite strange also they aren't to expensive for the smaller values AKA 100uF 100V. It gets to expensive for PSU in my opinion.
I tried the polar type first and then the non-polar, they are both very good. I think many people would prefer the polar version being not so warm sounding. But its as always down to personal taste.
M. Gregg
|ILoveHiFi [ 26 Sep 2019, 18:52 ]
|Post subject:
|Re: HIFI conditioning?
Instead of having extreme expensive caps in one place, one could have all hifi caps, say remove everything and use only the hifi caps.
Not even a single cheap cap in system.
Mouser has good stock of hifi caps and shipping is free after certain ammount, that that point if its fair price.
|M. Gregg [ 27 Sep 2019, 08:03 ]
|Post subject:
|Re: HIFI conditioning?
ILoveHiFi wrote:
Instead of having extreme expensive caps in one place, one could have all hifi caps, say remove everything and use only the hifi caps.
Not even a single cheap cap in system.
Mouser has good stock of hifi caps and shipping is free after certain ammount, that that point if its fair price.
Another way round the PSU is to use good quality Electrolytic caps at the rectifier input and do the upgrade in stages ie
Input from rectifier high ripple good quality cap, then either choke or resistor then better quality and bypass with HQ film or oil cap.
NB Interesting question: the resistor between the first cap and main cap if you use non-inductive type Vs inductive type.
The reason this is interesting is that a choke adds inductance, some argue that inductors stop the PSU powering a transient in the music.
So the argument begins none inductive parts are "better" then link this to none magnetic parts are better because polarised magnetic steel uses energy to demagnetise so high frequencies are cut in magnetic parts (this is often linked to ideas about demagnetising tape heads in cassette and reel to reel tape decks). However inductance in PSU's has always been a good way to remove RFI and noise, and so the use of HF inductors in PSU with notch filters to remove commutation noise.
NB the ideas about film cap bypass are interesting, the idea that low ESR gives fast energy release at transient, and so you can "voice" equipment to your personal taste. There is a minefield of problems with this because you tend to "voice" the system to compensate for room acoustics.
It sounds great in that room then take it somewhere else and it will "suck".<<<and so it is that bypass capacitor type has a marked effect on sound (even though it should have no effect).
The idea of synergy where mixing cap and or resistor types to give "good sound" does work, but its a real headache when you change a capacitor and instantly there is detail there that is in the music but you couldn't hear it before<<<frequency lift and cut.
M. Gregg
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England: World Capital of Dhimmitude, Grotesque Female Celebrities and Hatred of Jewish People
Reader comment on item: Britain's Encounter with Islamic Law
Submitted by James Burke (Canada), Apr 2, 2008 at 08:40
When I read about any of those topics, a part of me is lovin' it and a part of me is hating it.
A great website to read about that pathetic island is www.thereligionofpeace.com ; it also has links to the Brussels Journal with articles about European bend over contests.
The topic that I enjoy most of all is how the British Institutions are petrified of Islam ( including the monarchy).
This issue will not just dry up and go away. Something really bad will happen; Big Ben >> Big Burnt perhaps? A massive explosion in the tube or in a crowded pub or Heathrow.
Fortunately I live in Canada so I will have a great seat to the street fighting in Britain when the action really begins.
Unfortunately I live in Canada that is home to an Anglo saxon protestant self hating culture.
More and more I am hearing a British accent spoken here which I am against because the Brits will bring their Israel bashing ( which we have enough of from our own corrupt left wing freaks ) and their nauseating "beer and vomit and beer some more culture" with them.
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PCOM Georgia held a virtual commencement on Wednesday, July 29, for the Doctor of Pharmacy (PharmD) and graduate programs Class of 2020.
In a 47-minute online ceremony viewed 4,000+ times to date, 162 PCOM Georgia students ceremonially received master's and doctoral degrees while family members and friends engaged online and cheered them on.
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text: My first test E cycle was started 2 months ago, it has been about 8 weeks and I am shooting twice a week. so 16 shots in give or take. I'm doing 500mg a week as advised. eating over 300g protein, lifting EOD. why am i not seeing any results? no libido up either. the gear is not fake, the codes matchup from pharmacom.


text:
I have an old highlander and have been looking around for something new. I'm a woodworker by hobby and want a lumber friendly vehicle. Not open like a pickup and washable. I'd pretty much settled on the Honda Element but just heard that this is it's last year. No 2012 model.
I want to get down to the Amish lumber yards in the NE Ohio winter.
Is this a bad thing or good thing? For resale value eventually? Parts? Finding a bargin near the fall?
I have an old highlander and have been looking around for something new. I'm a woodworker by hobby and want a lumber friendly vehicle. Not open like a pickup and washable. I'd pretty much settled on the Honda Element but just heard that this is it's last year. No 2012 model.
If you're going to be using it as a work truck, resale value is going to drop anyway. That said, being a discontinued model doesn't mean it will be worthless when you're ready to sell.
Not sure what you are asking? Honda Element has been a solid vehicle. There will be parts available for many years to come. If you are wondering if an Element is a good vehicle for the future, I'd say yes.
Thanks! Like I said woodworking is a hobby. I am wondering about resale or if there is any downside to buying a a discontiued vehicle. I'd like it to be worth something when it is paid off.
And Thanks again,
No worry about the Element, standard Honda parts throughout.
But it's not 'washable', as in 'hose it out'. That rubber floor is misleading, there's electronics underneath. Do NOT hose it out!
Thanks, but I'm asking about the element not the Pilot.
I was thinking Element, typing Pilot. My (corrected) comments apply to the Element, not the Pilot.
The Element is the crude brother of the CRV and has been since it's inception. Not to worry, though unless you have dogs, I would not get one over a 4 cyl compact PU with a taller cap. That would be my first choice. The actual load capacity is quite small regardless of the room. You'll be pushing the limit with wood and tools IMO.
There are reasons it's discontinued.
Any time a manufacturer comes out with a new model, the previous vehicle becomes a discontinued model. I think that the engine and running gear are the same as the Honda CRV. If the Honda Element fits your needs, then this might be the vehicle for you. One of our vehicles is a 2003 Toyota 4Runner. In the last year or so, Toyota redesigned the 4Runner, so effectively I have a discontinued model.
I don't think resale will be drastically affected. A year ago, we decided to sell our 2006 Chevrolet Uplander to our son who needed a better vehicle. I would have bought a new Uplander, but GM no longer makes minivans. When I went shopping for a used GM minivan, it seemed to me that the GM minivans held their value well–the prices were too high. In fact, I decided I was better off to purchase a new Toyota Sienna minivan. Our 2003 4Runner has held its value very well, but there is no way we will give it up.
As others have mentioned, Element load capacity is limited. How big are the loads you want to carry (lbs.)?
Why even think about this vehicle, forget about it. I'm not questioning the quality of the vehicle but it has no hauling capacity for your needs.
Your a woodworker and need something to haul wood in. You will not get a board longer than 4 feet in the vehicle and close the lid. If you dont care if it hangs out then get a pick up.
If your buying rough lumber thats not cut to finished lengths and planed then the only thing you will haul will be bowl blanks.
I think though for it to officially be discontinued, a subsequent model in that area would have to be called something else. I don't see the 4runner as a discontinued model. Besides, anything they do for the Element to make it more competitive with a small van and increase it's capacity would be an improvement.
There are a plethora of cap choices and where I live, you can have them custom made with racks for your wood as well. Still think a PU is the choice for a working person like yourself. Crew cabs give you all the additional people hauling options as well, and in a compact PU there should be little difference in highway mileage. Add a utility trailer for special loads which an Element struggles with, and you're more than good to go, often for less money and with more used choices.
Now if they brought out a new Hybrid Element based upon the Pilot instead…hmmmmm
I wouldn't worry about a model disappearing…I'd worry about a whole make disappearing…Like Peugeot or Isuzu.
Or Pontiac or Oldsmobile or Saturn…
Not so much the GM brands, espcecially if it had a 'sister' model at Chevy or Buick.
Saab is another one to worry about, I'd bet they'll be gone in 2 years.
"Saab is another one to worry about…"
IIRC, the Chinese invested heavily in Saab along with Spyker. I doubt that the Chinese would let Saab go down any time soon. They don't work by the same rules as a publicly traded company.
I'm not aware of any Chinese investment in Saab. They bought Volvo, and Tata bought Jaguar/Land Rover, I think.
Article in today's WSJ about how Jaguar and Land Rover are looking good, but Saab's way down.
Thats my point, theres a butt load of better choices than the Element. I can even get 8 foot boards in a Taurus with the seats down and deck lid closed (and no, they are not hanging out the windows).
Take a look at one of these. Then you can drive any vehicle of your choosing. I pull one of these with a small compact car; easy to do.


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Bridgeport, OH Store (For all Internet-related inquires) 500 Hall Street Bridgeport, OH 43912 Phone: 740-635-1129 Hours:... M-F 7 AM to 7 PM Sat. 7 AM to 5 PM Sun. 9 AM to 3 PM Marietta, OH Store 15 Acme Street Marietta, OH 45750 Phone: 740-373-6686 Retail Hours: M-Th. 7 AM to 6 PM Fri & Sat. 7 AM to 7 PM Sun. 9 AM to 5 PM Rental Hours: M-F. 7 AM to 5 PM Sat. 7 AM to Noon Sun. Closed Parts...
Bridgeport Equipment and Tool is located at the address 500 Hall st Ste 2 in Bridgeport, Ohio 43912. They can be contacted via phone at (740) 635-1129 for pricing, hours and directions.
Bridgeport Equipment and Tool has an annual sales volume of 0 - 500K. .For more information contact Tom Knight, or go to www.bridgeportequipmentandtool.com
For maps and directions to Bridgeport Equipment and...
Bridgeport Equipment & Tool is your source for boots, work & safety apparel, equipment & tools. We carry a huge selection of apparel & boots for men, women & children at great prices! Choose from many brands, including John Deere, Carhartt, Carolina, Red Wing, Rocky & Matterhorn. Shop online or call us at 740-635-1129!
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Apparently the gun department at the Marietta, OH location didn't think I had any money to spend. Stood at the gun counter waiting for someone to help. Was walked past 3 times by workers. An older couple walked up and one of the older gentlemen working the counter walked right past me and went to help them. You can bet I will take my money elsewhere. You just lost a sale!
The Wurtland store are the most unprofessional people I have ever done business with. Thiefs! I will be spreading the word to ALL my business contacts.
Charleston store is very helpful and their prices fair and very good selection
If your not in the oil or excavation business your are the little man to this business...
i like working with the people at bridgerort in wurtland ky. good people. THANK YOU
Bridgeport Equipment & Tool Rentals & Sales can be found at Hall St 500. The following is offered: Lawn & Garden Equipment. The entry is present with us since Sep 8, 2010 and was last updated on Nov 14, 2013. In Bridgeport there are 1 other Lawn & Garden Equipment. An overview can be found here.
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Welcome to Bridgeport Equipment and Tool Most of our boots are at least 25% off retail prices and our discount boots clearance page offers boots at up to 50% off retail


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Kilkenny manager Brian Cody has no interest in the dynamic of renewing the rivalry with Liam Sheedy ahead of Sunday's All-Ireland Hurling Championship final with Tipperary in Croke Park.
Cody and Sheedy will clash for a third time in a decider after the two sides fought unlikely paths to the biggest day in the hurling calendar.
Asked if coming up against an old foe was on his mind, Cody said: "Not even close to entering my mind. At the end of the day the players will play the game on the field and whoever is on the line is irrelevant really once you get there.
"Liam Sheedy is a very, very good manager, he'll prepare the team as best he possibly can.
"He'll have a great ambition, we'll have a great ambition. It's Kilkenny against Tipperary. There's a tradition there, there's a history there. It's the All-Ireland final. Regardless of the opposition, you want to win the match.
"We're in the final on Sunday so that's a terrific place to be for both teams. It's what every team wants at the start of the year.
"To win it you have to be in it. It has been a very challenging year, with very competitive matches. We're delighted to be in it."
After a couple of years of re-building, Kilkenny have taken the scalps of Cork and Limerick on the road to this game, having earlier been defeated by Wexford in the Leinster final.
But throughout the year Kilkenny have stayed competitive and Cody has not been surprised by how his charges have grown.
"We have a lot of inexperienced players from the point of view from playing Championship hurling. We had players who were unavailable for a while. It's about learning along the way. There is a lot of matches played. At the same time I didn't think we were that far behind everybody else at the start of the year. We weren't beaten by much last year.
"We won the league last year. It was a question of working away and working towards where we wanted to get to. The players responded really, really well.
"I never make a secret of the fact I have great confidence in the panel that we have. The panel has been tested, used and they are good players with good attitudes and you always have a chance then.
"We were playing the All-Ireland champions the last day. To stay competitive in the game we had to be really, really strong throughout the game.
"We got a good start, built on that and they came on it in a huge way. We had to have a good resilience to keep going, try to stay ahead and it was a terrific game for everybody."
Many pundits believes that victory in Sunday's final would rank among Cody's greatest achievements in what would be a 12th All-Ireland, having once again sculpted a young group of players and mixed them with experience to become the best team in the land.
In closing the interview with RTÉ Sport's Marty Morrissey, he was asked for his reaction to that view.
Cody responded: "I don't have one. I have no reaction to it. I just do what I do. I'm enjoying doing what I do and as I always say regardless of what happens the players always win the game.
"It would be a terrific achievement for the players and everyone involved in it. But any time you win an All-Ireland it's a terrific achievement for anybody involved in it.
"It's not (different). I'm managing the Kilkenny senior hurling team for the last while and it's never different from the point of view of what you want to achieve, of what you have to put into it and what you try to do.
"Essentially it's all about everybody working together but there's a management team there, there's a backroom team there and most importantly of all there are players there. Matches are always won on the pitch.
"It's a great time. You've got to enjoy the build-up to the All-Ireland final. It's a hugely enjoyable time. It's a hugely busy time as well but where else would you want to be?"
Follow the All-Ireland hurling final between Kilkenny and Tipperary (Sunday 3.30pm) via our live blogs on RTÉ.ie and the News Now app, watch live on RTÉ2 or listen to radio commentary on RTÉ Radio 1 and RTÉ Raidió na Gaeltachta.


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Baker Hughes /zigman2/quotes/205323712/composite BKR +2.72% on Friday reported that the number of active U.S. rigs drilling for oil rose by 14 to 673 this week. That followed declines for oil rigs in each of the past three weeks. The total active U.S. rig count, meanwhile, was up 15 from last week to 796, according to Baker Hughes. Oil prices extended their decline, with February West Texas Intermediate crude down 20 cents, or 0.3%, at $58.32 a barrel. It was trading at $58.50 before the rig data.
Read the full story:
Oil futures suffer a second weekly decline


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Signal Wedge and Butterfly
Smart and simple Indicator based on wolves waves reversal pattern also near to falling and rising wedge and butterfly patterns
with Stoploss and entry signal
preferred time frame M30 : with parameters bars count used for calculation = 200 and moving average for accuracy = 100;
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higher timeframe = lower input
!!! important note :::
Indicator don't back draw when first installed on Chart
once installed wait for new drawn patterns and signals
use strategy tester and you will see it working on old history


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2 Corporate Drive,
Suite 335,
Experience Makes a Difference
Our Team Is Here For You Despite the challenges posed by the current COVID-19 situation, we want to reassure our valued customers that we are continuing to provide the same high level of service and availability you've come to expect and deserve. Like you, we're monitoring the situation closely and taking measures to protect the health of our employees, customers and communities. In an effort to comply with the clear directives from federal, state and local governments, we currently will not be accepting walk-in or in-person appointments at our office. Our employees will continue to remain available at regular business hours through telephone, e-mail and our website. Please contact us with any questions. We wish you the best during these challenging times.
Our Risk Management experts consider all aspects of your business, along with your financial strategy to recommend appropriate risk mitigating solutions.
Our Private Client Group takes the time to understand your unique needs and recommend insurance that protects what matters most for you and your family.
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Check out what is going on at ACBI!
Layoffs During Leave Require Adequate Documentation
As we enter what appears to be another wave of the pandemic, if your business if affected and you need to downsize it is important that you have documentation for any termination or layoff.
Paying Ransomware Gangs Could Violate Regulations
In today's hyper-connected world, cyber threats are everywhere and ransomware attacks have continued to increase throughout the country.
What Is and Isn't Covered by Homeowners Insurance
After the recent storms with downed trees and property damage, it's as important as ever to understand what IS and what ISN'T covered under your homeowners policy.


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I Was a Soul Train Dancer: Robi Reed
Samantha Knowles Draws Attention to Black Hair Discrimination
Fans Will Not Be Happy About This Male R&B Singer Calling Out Beyoncé, SZA And Cardi B
Hip-Hop Reacts To The Tragic Death Of Leah LaBelle
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Man Films Racist Old Navy Encounter Where Store Managers Accused Him Of Stealing The Jacket He Wore To The Store
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I'm hosting a postscreening Q&A at London's Regent Street Cinema on Sunday Dec 15th (CANCELLED)
UPDATE: Sadly, this Q&A has now been cancelled. The screening of the film will go on, but I won't be there. Apologies to anyone who was looking forward to this, but I'm not the one who cancelled.
In the London area? Fancy checking out Estonia's submission to last year's Oscars, which screened at this year's Seattle International Film Festival but which doesn't have a UK or US release date yet? Come see Take It or Leave It at the historical Regent Street Cinema next Sunday, December 15th. I'll be hosting a Q&A afterward with director Liina Trishkina-Vanhatalo.
A synopsis, from the film's official site:
Here's the trailer:
Tickets for the event are available at the Regent Street Cinema site.
Please join us!


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Located on a tree lined street , this unique , stunning , custom designed home , with attached CARPORT , is in the heart of the Bella Vista neighborhood. This corner property, at 8th and Catharine, has amazing light and is In impeccable condition . Recent renovation with meticulous attention to detail. This contemporary home, with loft like ambiance, has 3 bedrooms and 3 full baths. There is 2000 SF of living space plus 400 SF of finished basement space. Also, a large roof top space with 360 degree skyline views for an fabulous roof deck. Enter the home through a beautiful custom Mahogany door which leads to a spacious foyer with double coat closet. The 1st floor suite with full tiled bath, is useful as a guest room, home office or exercise room. From entry foyer, a straight stairway with brass handrail leads to the dramatic open plan Living Room Dining Room and Kitchen with excellent natural light, high ceilings and oak hardwood floors . Corner marble wood burning fireplace in Living Room. Spacious separate dining room opens to the cook~s kitchen. Then kitchen has generous storage in custom cherry cabinets, stainless appliances and white quartz counter tops. 3rd floor has Master Bedroom with luxurious ensuite bath with double sinks , glass shower and tub, vanity and linen closet. Large closets in bedroom. In addition, there is a 2nd bedroom , with generous closet space and full tiled bath.Stairway rises to large roof space.Refrigerator, washer and dryer included.
Based on the average sale price from the Fredicksburg, VA office
Let's determine your purchasing power. Working with my mortgage partner, you'll have the information you need to shop for a home with confidence.
Default based on a 30-year fixed rate of 4.38% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA, or jumbo loans.
801 S 8Th Street Philadelphia, PA is a Single Family Home for sale at $579000 with 2380 sqft and a lot size of 871 SqFt Acre(s). 801 S 8Th Street Philadelphia has 3 bedrooms, 3 baths and was built in 1989. The property's zip code is 19147 which is in Philadelphia, PA
*Information deemed reliable but not guaranteed.
Financial calculator disclaimer: Default based on a 30-year fixed rate of 4.38% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA or jumbo loans.
All information deemed reliable, but not guaranteed, and should be independently verified. The real estate information and related content displayed on this site is provided for consumers personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.


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Upcoming Hikes 2020/2021
You are welcome to join any of the following hikes but you do so at your own risk.
Please consider joining and supporting hiking organizations such as the Grand Valley Trails Association, the Avon Trail, the Guelph Hiking Club, the Bruce Trail Conservancy, the Thames Valley Hiking Association, and the Elgin Hiking Trail Club. See Hike Ontario and the Ontario Trails Council for other suggestions.
Smoking is not permitted on hikes.
Dogs are not allowed on most hikes unless otherwise stated.
Hikes usually proceed "rain or shine". Exceptions would be if there is severe weather with road closures or imminent lightning storms.
Note that it states "Depart at ..." in each description. That means you must be at the designated meeting place well ahead of time.
Some hikes are loops while others are linear. Linear hikes require a car shuttle at the start of the hike and at the end of the hike. If it is a car shuttle hike, we usually meet at the end point. Come prepared to participate in the car shuttle and ensure there are at least two to three empty seats in your car. Also, you need room in the car trunk for back packs, etc.
Some of these hikes may be offered through a hiking organization in which case you must be prepared to sign a "Waiver of Liability and Assumption of Risk" form before the hike starts.
Hike Rating
To help you decide if a hike is suitable for you, I tend to use a hike rating system similar to that used by organizations such as the Bruce Trail Conservancy, Hike Ontario and the Grand Valley Trails Association. There are three aspects that describe or rate the hike. No attempt is made to provide a total time for a hike.
Pace (or Speed)
Leisurely = less than 2 km/h Slow = 2 to 3 km/h
Moderate = 3 to 4 km/h Fast = 5 km/h or greater
Currently my hikes tend to be at a slow to moderate speed.
Level of Difficulty (LOD)/Terrain
Easy or Level 1 – Well–defined trails, gentle inclines. Hiking boots not required, but trails may be wet. Is suitable for beginners. This level is recommended for newcomers
if the distance is suitable.
Normal or Level 2 – Generally on trail. May be hilly, light bush whacking, some rough spots or obstacles. Sturdy hiking boots are necessary.
Strenuous or Level 3 – Rough terrain with one or more of the following: extensive bushwhacking, steep sections, long climbs and descents, beaver dams, rock scrambling or other obstacles. Boots, Level 2 experience, and a high level of fitness essential. Long pants and sleeves recommended.
Distance is stated in kilometres (km). [1 kilometre = 0.621371192 mile].
2020-2021 Fall/Winter Hikes
Special Message
It has been several weeks since the Covid-19 Pandemic was declared. Some trails have re-opened and schools are opening. As you can appreciate, group hikes, as we knew them, have been curtailed. A few smaller group hikes are being allowed under strict and necessary conditions. Some hike leaders, myself included, are reluctant to resume published group hikes as we did pre-pandemic. I will continue personal hiking/walking this fall (2020). At some point I may start publishing a limited number of hikes in the space below. If you have never hiked with me before and need ideas for some Ontario hikes, please check my Master Index of Hikes. Until then, happy hiking and stay safe. Check here for any last-minute changes, including early on the morning of the hike.


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Americans Gearing-up for Civil War; Gun Sales UP 95%, Ammo Sales UP 139%
Hal Turner Radio Show
The gun industry has never seen anything like 2020, and the explosion in sales driven by the concerns over rising crime, protests, the coronavirus crisis, and the presidential election are expected to continue. It's that last itme that matters – Americans are actually now TALKING about "Civil War."
"Bottom line is that there has never been a sustained surge in firearm sales quite like what we are in the midst of," the National Shooting Sports Foundation, an industry trade group, said in a report.
New sales and customer data collected from gun stores are even more shocking than the latest historic level of FBI background checks for purchases, security clearances, and concealed carry permits.
Talk of "civil war" is now very much out on the open and Americans already seem to know who the "enemy" is: Communists from BLM and ANTIFA.


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Back to Journals » International Journal of Nanomedicine » Volume 12
Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model
Authors Wolf-Grosse S, Rokstad AM, Ali S, Lambris JD, Mollnes TE, Nilsen AM, Stenvik J
Received 8 March 2017
Accepted for publication 11 April 2017
Published 23 May 2017 Volume 2017:12 Pages 3927—3940
DOI https://doi.org/10.2147/IJN.S136453
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Thomas Webster
Susann Wolf-Grosse,1 Anne Mari Rokstad,1–3 Syed Ali,4 John D Lambris,5 Tom E Mollnes,2,6–9 Asbjørn M Nilsen,1,* Jørgen Stenvik1,2,*
1Department of Cancer Research and Molecular Medicine, 2Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, 3Central Norway Regional Health Authority, Stjørdal, Norway; 4Division of Neurotoxicology, US FDA/National Center for Toxicological Research, Jefferson, AR, 5Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA; 6Department of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, 7Research Laboratory, Nordland Hospital, Bodø, 8K.G. Jebsen Inflammatory Research Center, University of Oslo, Oslo, 9Faculty of Health Sciences, K.G. Jebsen Thrombosis Research and Expertise Center, University of Tromsø, Tromsø, Norway
*These authors contributed equally to this work
Abstract: Iron oxide nanoparticles (IONPs) are promising nanomaterials for biomedical applications. However, their inflammatory potential has not been fully established. Here, we used a lepirudin anti-coagulated human whole blood model to evaluate the potential of 10 nm IONPs to activate the complement system and induce cytokine production. Reactive oxygen species and cell death were also assessed. The IONPs activated complement, as measured by C3a, C5a and sC5b-9, and induced the production of pro-inflammatory cytokines in a particle-dose dependent manner, with the strongest response at 10 µg/mL IONPs. Complement inhibitors at C3 (compstatin analog Cp40) and C5 (eculizumab) levels completely inhibited complement activation and secretion of inflammatory mediators induced by the IONPs. Additionally, blockade of complement receptors C3aR and C5aR1 significantly reduced the levels of various cytokines, indicating that the particle-induced secretion of inflammatory mediators is mainly C5a and C3a mediated. The IONPs did not induce cell death or reactive oxygen species, which further suggests that complement activation alone was responsible for most of the particle-induced cytokines. These data suggest that the lepirudin anti-coagulated human whole blood model is a valuable ex vivo system to study the inflammatory potential of IONPs. We conclude that IONPs induce complement-mediated cytokine secretion in human whole blood.
Keywords: iron oxide nanoparticles, human whole blood, complement activation, cytokines, reactive oxygen species, complement inhibitors
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]


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text: LAFLER, Donald W. Age 93, of East Sandwich, MA, passed away on August 20th at home. A Memorial Mass will be held at Corpus Christi Parish, East Sandwich on Saturday, August 24th at 1:00 p.m. Burial will be private. Mr. Lafler was born August 14, 1926 in Batavia, New York to John Lafler and Edith Lambke Lafler. He served in the U.S. Army from 1944 to 1946, and subsequently graduated from Miami University in Oxford, Ohio with a Bachelor's degree in 1949. He enjoyed a career in retail management, rising to Vice President and CEO posts at various firms. He taught Retail Management at Cape Cod Community College, and helped create a new cathedral at Corpus Christi Parish in Sandwich, MA. In July 1951, Mr. Lafler married Shirley Rogers of LeRoy, New York. He was preceded in death by son John F. Lafler. He is survived by Shirley Rogers Lafler, beloved wife of 68 years, his children Mary Lafler James, Steven Lafler, Nancy Elizabeth Lafler, and Judy Lafler Converse, grandchildren Dorian James, Daniel James Bandit, Christian James, Molly James Banasiak, Ben Converse, Maxwell Lafler and Genevieve Lafler, and great-grandchildren Wolf Bandit, Juniper Bandit, and Julian James. For directions & online condolences, please visit www.nickersonbournefuneralhome.com


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When I bought my first home I never thought I would have to worry about renting again. Well, life happens, and I ended up renting for about four. I think the musical Rent sucked. CMV. Terribly overrated. Boring songs with obtuse lyrics. The whole story is ludicrous when applied to AIDS in the era when it.
By Nadal - 03:02
Breizhtux.info › redeye › ct-redeye-xpm
By Garan - 04:55
Thanks, Joint Center for Housing Studies of Harvard University report, for confirming what we all already felt: The rent really is too damn high.
By Zulkit - 10:52
The latest Tweets from Rent Sucks (@Rent_Sucks). Luxury Chicago homes for less. Chicago USA.


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Add a touch of sophistication to your streetwear with these men's Maxwell II trainers from Tommy Hilfiger. Crafted with a leather upper in a magnet and black colourway, the trainers feature tonal stitching throughout. Sat upon a responsive midsole, they are perfect for all day wear. The 'T' and 'H' shaped sole adds grippy traction to every step, and the shoes are finished with Tommy Hilfiger branding to the side, heel piece and tongue.
Care & MaterialLeather Upper/Synthetic Sole
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Aug 06, 2016 · Bersa Thunder 380 APC slide racks back when the gun drops or hit too hard is this a malfunction or how the gun is. Bersa Thunder 380 APC slide racks back when the gun drops or hit too hard is this.
APC 380 Groenink #1 color palette by dukecolor47. Artist Palette ChallengeAPC #380 Chuck Groenink.
I'm contemplating purchasing a Sig P238 (.380 acp). I currently own a Springfield XD subcompact in 9mm, but the double stack mag pistol is a brick compared to the minuscule P238.
The .380 ACP cartridge was derived from Browning's earlier .38 ACP design, which was only marginally more powerful. The .380 ACP was designed to be truly rimless, with headspace on the case mouth instead of the rim for better accuracy.
The .380 ACP cartridge was derived from Browning's earlier .38 ACP design, which was only marginally more powerful. The .380 ACP was designed to be truly rimless, with headspace on the case mouth instead of the rim for better accuracy.
ARMSLIST – For Sale/Trade: 380 APC. www.armslist.com. ARMSLIST – For Sale: Smith and Wesson Bodyguard .380 APC.
380 Ammo Defense Rounds The .380 ACP round, also called the .380 Auto (among other designations), is a popular handgun cartridge that has been used for self defense, hunting In this post, let's explore what options are the best 380 acp ammo for self-defense available today. 380 automatic colt pistol ammunition was first. Personal Defense Ammo, Unlike Anything on
Chart that specifies the APC Modular Power Distribution Units that support the installation of APC 400V Power Distribution Modules and specifies compatible APC Rack PDUs for each PDM.
The .38 ACP (Automatic Colt Pistol), also known as the .38 Auto, is a pistol cartridge that was introduced at the turn of the 20th century for the John Browning-designed Colt M1900. It was first used in Colt's Model 1897 prototype, which he did not produce.
Glock 42 Gun: Why the Smallest of All Glocks is Truly Special – The pistol combines the Austrian gun manufacturer's gun operating system with the .380 ACP pistol cartridge. The result is both a pistol for concealed carriers who desire a low recoil pistol and the.
A7-APC / A7APC (Qatar Airways) – Aircraft info, flight history, flight schedule and flight playback. Flight history for aircraft – A7-APC. AIRCRAFT Airbus A380-861.
Smith & Wesson M&P 380 Shield EZ, 8 Rounds .380 ACP, Ambi Thumb Safety Black Smith Browning 1911-380 Black Label .380 ACP Semi Auto Pistol 4.25" Barrel 8 Rounds Co.
Remington UMC Range Bucket Handgun Ammunition .380 Auto 95 gr FMJ 955 fps 300/ct – All UMC handgun ammunition is American-made in Lonoke, Arkansas, using first-quality, factory-fresh brass and clean-shooting Kleanbore Manufacturer Remington Caliber .380 ACP Grain 95 gr Bullet Type FMJ Velocity 955 fps Rounds 300 Brand UMC UPC 047700477107 Mfg Part# 23978 Product Number: RT23978
75 inches wide. By comparison, the Glock 26, also in .380 ACP caliber, is .98 inches wide and the Ruger LCP has a width of .82 inches. The pistol is approximately 4.3 inches high. The Bodyguard 380 is.
Springfield Armory's first new pistol introduction of 2018—the 911 .380 ACP—is the manufacturer's most concealable firearm to date. Springfield says it has optimized the frame-to-slide-to-trigger.
Bersa Thunder 380 APC slide racks back when the gun drops or hit too hard is this a malfunction or how the gun is.
Imported to the U.S. by Eagle Imports of New Jersey, the Bersa Thunder 380 chambered in .380 ACP offers a top-notch set of features for real world prices under $300. In fact, everything you need for a.
Code : APC-380 Size W : 22 cm. HomeGalleryANTIQUEAPC-380. Home. About Us.
380 Auto +P Ammo 90 gr. Jacketed Hollow Point @ 1,200 fps M.E. / 288 ft lbs 20 Round Box. ITEM 27C. The 380 auto inhabits a valuable and useful place in our society, mostly because of the easily concealable, tiny pistols chambered for it.
his .380 ACP automatic pistol is a bit large compared to most competitors' pocket pistols, but it's still a viable conceal and carry option. It's got a 5.5 lb trigger pull and, at 5.94 inches in.
Отмена. Месяц бесплатно. .380 APC. Revision Relapse.
Smith & Wesson M&P 380 Shield EZ | First Shots – 380 ACP from a large manufacturer. Many of us that digest gun content thought that the M&P 380 Shield EZ was a gun that no one had asked for and was a solution to a problem that didn't exist. How.
The .380 XTP, or parts of it, exited the 9-inch block. The cavity at the widest point was exactly like that of the .32 ACP: 3 inches. What was interesting was that the .380's cavity tapered down to a half-inch in diameter as it approached the exit, as opposed to the 1-inch diameter of the .32.
Nov 05, 2016 · in this video, i help a relative reload some .380 pistol rounds.
Cheap .380 ACP (Auto) ammo for sale at wholesale prices. Buy your .380 ACP (Auto) ammunition in bulk at Ammo.com. Live inventory + same day shipping!
380 pocket pistol and as a result is still snappy. It's not a range gun, and should not be treated as such. The .380 ACP semi-automatic pistol is one of the most popular categories of concealed carry.
The .380 Automatic Colt Pistol (ACP) has come a long way since John Moses Browning designed this little straight-walled cartridge over a century ago. Once considered too small for self-defense work, the .380 ACP is now much more effective at stopping attackers than it once was thanks in large part.
In many South American countries, the higher pistol caliber that civilians are allowed to own is the .380 ACP. As a result, the Thunder 380 is enormously popular in civilian hands in countries such as.
Unfortunately, each of these pistols and others in their class suffer from a number of serious flaws. The .380 ACP semi-automatic pistol is one of the most popular categories of concealed carry.


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Suddenly this morning I am seeing a banner I don't recall seeing before. It is at the top of the page and has the McAfee logo and name on the left, then the stop circle (circle with line across), then "We tested this page and blocked content that comes from potentially dangerous or suspicious sites. Allow this content only if your're sure it comes from safe sites.", a text box with "View all blocked content" and finally the "x" for closing the banner. I am using Windows XP and McAfee Anti Virus Plus and have made no recent changes in settings for either. RIght now I am looking at the banner as it appears even on this page. It is not associated with https but, when it occurs with it, I receive a popup window entitled Security Warning asking what I want to do. This is just the Windows security popup, I think. But the banner occurs on other sites (e.g. counterpunch.org. I ignored it at first because it is feasible for ordinary sites to occasionally have questionable content. But this community that is run by McAfee?
Do I have a problem or a bad setting?
I am getting red rated warnings for many blog sites from McAfee Site Advisor : "Warning we tested this site and found its dangerous to visit" This is unusual and appears to be a problem with McAfee although I am not 100% sure.
@annalee : I've seen that black banner before, on sites which include 3rd-party content. The problem you see appears to have started very recently - the first notice of it by a poster was by jmckee HERE yesterday. We've been discussing it privately for the past 24 hours and haven't got to the bottom of it yet. It's possible that one of the external sites providing webpage content has introduced something that they shouldn't use, or that their site has been flagged as suspect for some reason. Until we can find out which site that is, we're in the dark too.
@joeblow : blog sites are often created using Wordpress or Joomla. Both of those have had major security weaknesses exposed recently which have been exploited by hackers. If you come across another one, can you post a message to the SiteAdvisor section with the URL and I'll look into it.
One thing to note : I only see the banner on IE. In Chrome I sometimes see the symbol which indicates a plug-in has been blocked. In Chrome and Firefox I have Abine's DoNotTrack+, but I couldn't get that to work in IE. That might be significant.
I have experienced the above issue using Firefox. Am I to understand the SiteAdvisor warning is connected to the blog sites being created using Wordpress or Joomla? That would mean many sites will be considered dangerous. Is there a way to verify URLs?
@joeblow :
If what you are seeing is the big blocking page put up by SiteAdvisor that's a different issue from the one the first poster was asking about. SiteAdvisor uses TrustedSource, which can detect problems almost in real-time. The black banner says content on the page from a 3rd-party (advertiser, whatever) is not to be trusted.
As for the blog sites : not all sites created with WordPress or Joomla will have a problem. Most problems were on WordPress anyway, on sites that hadn't been updated to the latest version. Sites running an older version of WordPress have a security weakness which is still being targeted.
There are many tools available to test websites, but you can generally rely on the visual clues provided by SiteAdvisor and WOT. If either shows a Red status, it should be investigated.Message was edited by: Hayton - correcting a messed-up edit - on 27/05/12 16:26:35 IST
I first saw the black box with the McAfee banner "We tested this page . . . " when going to my Google Blogger page on my laptop via Firefox. I also get it on my desktop computer using Google Chrome, and as others have said, it even appears at the top of the pages in this forum. I would think there's no dangerous content on this site, is there?
@carmelam : it's not a site problem, it's something to do with external content from (we're pretty sure) AddThis.
@pianoboy : already tried that. The banner goes away but comes back if the page is reloaded. It's tracking software doing something that it shouldn't. SiteAdvisor hasn't been updated, so it's a change in someone else's program causing this.Message was edited by: Hayton on 28/05/12 15:18:56 IST
Thanks, Hayton. Could you do me a favor and let us know when you figure it out especially if we need to do something on our computers? And, yes, I am using IE 8.
I had the same problem in firefox 12 but not in ie9. By deleteing all the cookies in firefox the problem disapeared.
Suggest you try the same in ie8.
Apologies for this warning. Rest assured we're investigating this issue and will resolve asap. Unfortuantely today is a holiday in the US so please bear with us. Thanks,
Corporate Headquarters
6220 America Center Drive
San Jose, CA 95002 USA
Consumer Support | Enterprise Support | McAfee.com


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Beyond safety considerations for other patients and staff in the immediate vicinity, those practising in the field of infectious diseases, microbiology and virology must have proficient knowledge, skills and behaviour relating to the public health considerations of communicable disease control. Practitioners must be able to describe the public health issues relating to communicable diseases and to specific infections (incubation periods, transmission routes, vaccinations available, need for mandatory notification), as well as understand basic epidemiological methods and the functions of health protection and environmental health teams.
The cornerstone of practice for practitioners in infectious diseases, microbiology and virology is the ability to diagnose and manage important clinical syndromes where infection is in the differential diagnosis. Practitioners must hold a detailed knowledge (covering the epidemiology, clinical presentation, relevant investigations and management and prognosis) of both community-acquired and healthcare-associated infections. This knowledge must cover infections in all body compartments and those causing systemic infections (such as blood-borne viruses). This must incorporate patients presenting from the community, and infections which develop among those already undergoing healthcare treatment for other conditions. In this latter group, infections among surgical patients and those colonised and infected with multi-drug-resistant organisms must be able to be managed with confidence. Similarly, common clinical infection syndromes presenting among patients returning from travel abroad must be able to be recognised, investigated appropriately and treated promptly. Practitioners must also be able to manage infections among special populations, including itinerant populations, those who may misuse drugs or alcohol, those at the extremes of age or who are pregnant and immunocompromised individuals. Specific to immunocompromised individuals, this should encompass both those with primary and with secondary immunocompromise.
In a clinical setting, practising infectious diseases medicine must incorporate knowledge, skills and behaviour to prevent onward spread of communicable diseases to other patients and to members of staff. The mode of transmission of communicable diseases must be understood, and practitioners must be able to interrupt their onward transmission. This includes the use of personal protective equipment for clinical interactions; from the types of equipment available, to their indication and the legislation surrounding their use (including Health and Safety at work). This also includes the use of isolation facilities; the indications for side rooms, negative pressure ventilation rooms; and when and how to arrange transfer to high-consequence infectious diseases units.
Patients living with human immunodeficiency virus (HIV) have particular health needs relating to their diagnosis, the opportunistic infections which can affect them, and the chronic disease management of their condition which is impacted by the disease process itself and the medication used to control it. Practitioners working with patients living with human immunodeficiency virus must hold knowledge of the pathophysiology and natural history of the disease, the therapeutic options available for virological control and the likely complication from HIV and the medications. Practitioners must be able to safely monitor and interpret the test results of patients living with human immunodeficiency virus. They must also be able to advise on strategies to decrease onwards transmission of HIV, including pre-and post-exposure prophylaxis. Practitioners managing patients living with human immunodeficiency virus must be able to identify and treat the opportunistic infections which may arise.
The nature of infectious diseases means that they are not bound by political or social boundaries. Practitioners in infectious diseases, microbiology and virology must, therefore, be competent in the recognition and management of imported infections and be aware of mechanisms to identify prevalent infections in different geographical areas. Practitioners must also be able to recognise problems of non-communicable diseases among immigrants from low- and middle-income settings. Practitioners in infectious diseases must also be competent in giving pre-travel medical advice including vaccination against communicable diseases and prophylaxis (both physical and chemical).
Microbial and host cellular biology and interactions dictate the breadth of clinical infection practice, from colonisation to invasion to infection. Understanding the classifications used for bacteria, viruses, fungi and parasites aids clinical and laboratory diagnosis and ultimately patient management. Understanding the common host responses to infective agents at the cellular level enables appropriate clinical management both with direct acting anti-infectives and other supportive therapy.
A basic understanding of the mechanism of action and indication for antimicrobials is held by most prescribers. The key properties of different classes of antimicrobials, their anticipated side effects and the spectrum of activity against different pathogens is inherent in most undergraduate and post-graduate medical curricula. Practitioners in the fields of infectious diseases, microbiology and virology must have a firm grasp of this knowledge, and should be able to apply it to patients with bacterial, viral, fungal or parasitic infections. They must be able to integrate this knowledge with the pharmacokinetic properties of the antimicrobials, and should be able to adapt this in differing patient populations including those with renal impairment or on renal replacement therapy and those with allergies or other host factors.
Limiting the spread of communicable diseases within a healthcare setting is integral to patient safety and clinical practice. Practitioners in infectious diseases, microbiology and virology often lead infection prevention and control teams, and are often responsible for creating and implementing policies and ensuring their effectiveness. They are also often responsible for investigating outbreaks when there are lapses in practice, or other causes for onwards transmission of infectious agents.
To provide an effective infection specialist service, practitioners must be conversant in pre-analytical, analytical and post-analytical elements of laboratory practice, irrespective of the specific areas of infectious diseases undertaken on a day-to-day basis. Pre-analytical skills and knowledge will include areas such as understanding the microbial differential diagnoses sufficiently to advise on and obtain the correct tests on the optimal sample types, be this for culture or for serological or genetic diagnostic tests. Pre-analytical skills also help practitioners identify where tests will not aid diagnosis, including for conditions which are currently diagnosed clinically and for which laboratory diagnostics do not currently exist. Analytical skills and understanding will vary depending on the area of practice, but will include safe laboratory work, the strengths and limitations of different tests, the impact of quality assurance and quality control and the cost implications of different modalities. Post-analytical skills and understanding will include contextualisation of results in each patients' care, awareness of positive and negative predictive values of different tests and implications for further diagnostics including reflex testing.
Practitioners in the field of infectious diseases, microbiology and virology must be proficient in advising on vaccination against communicable diseases. Practitioners must have a working knowledge of World Health Organisation's (WHO) childhood vaccination schedules, occupationally indicated vaccinations and the use and timing of post-exposure vaccinations. Practitioners should also be aware of adverse event profiles of vaccines and of the contraindications to certain vaccine preparations in certain patient cohorts.
To analyze influential infectious diseases, antimicrobial stewardship, infection control, or medical microbiology blogs and bloggers
World wide web
We conducted a systematic search for blogs in accordance with the PRISMA guidelines in September 2015.
A snowball sampling approach was applied to identify blogs using various search engines. Blogs were eligible if they (1) focused on infectious diseases, antimicrobial stewardship, infection control, or medical microbiology; (2) were intended for health professionals; and (3) were written in English and (4) were updated regularly. We mapped blog and blogger characteristics and used an innovative tool to assess the architecture and content of the included blogs. The motivations and perceptions of bloggers and readers were also assessed.
A total of 88 blogs were identified. Moreover, 28 blogs (32%) focused on infectious diseases, 46 (52%) focused on medical microbiology, and 14 (16%) focused on infection control or antimicrobial stewardship. Bloggers were mainly male with medical doctorates and/or PhDs; 32 bloggers (36%) posted at least weekly; and 51 (58%) had a research purpose. The aims were considered clear for 23 blogs (26%), and the field covered was considered broad for 25 blogs (28%). Presentation was considered good for 22 blogs (25%), 51 blogs (58%) were easy to read, and 46 blogs (52%) included expert interpretation. Among the top 10 blogs, 3 focused on infectious diseases, 6 focused on medical microbiology, and 2 focused on infection control (2 were equally ranked). The bloggers we questioned were motivated to share their independent expertise and opinions. Readers appreciated the concise messages on scientific topics and practical updates.
This study describes high-level blogs in the fields of infectious diseases, infection control, and medical microbiology. Our findings suggest ways in which bloggers should build/orientate blogs for readers, and we have highlighted current gaps in blog topics such as antimicrobial stewardship.
Infect. Control Hosp. Epidemiol 2017;38:832–839
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