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Hello everyone! Let's use this thread to get to know each other. Just say hi and a few words about who you are, maybe what are you building or learning with Repl.it.
If you're not comfortable sharing anything then share something fun 😉
Hi, my name is Claude and I'm a software engineer currently working on a project named Atlas toolkit, hence my username.
The goal of the toolkit is to provide a way as easy as possible to add a simple GUI to programs, in which ever language they are coded. The toolkit is not for skilled developers, but rather for hobbyists. It's for those who want to make programs that benefit from a GUI, but without having to bother with frameworks way too complicated for what they want to do.
I'm currently focusing on Python, but I plan to provide the toolkit for as much languages as possible, and I'm glad that I've found Repl.it, so people can test the toolkit without having to install a development environment.
Repl.it is almost perfect, except that my repls have to be forked in order to work properly. Probably because of the way my toolkit works. It's a little annoying, and if you have an idea how to avoid this…
Thanks for reading!

subset: commoncrawl


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Never one to shy away from teasing his future initiatives, Kanye West is heading into the Fall/Winter season with a full-fledged plan of busting out a plethora of more Yeezy colorways. Teased yesterday through Twitter, the latter half of 2020's lineup includes a boatload of new colorways, and one that is slated to drop around Christmas time is the adidas Yeezy 700 v3 "Clay Brown".
Unlike the recently-released "Azareth" makeup, this impending variation diverts back to Kanye's signature recipe of using darker, neutral toned design language. Based off of this first look, we can gather that the pair's uppers will be primarily hued with black Primeknit and cages, and will be feature tan streaks running through the mid-foot. Its foundational piece below deviates slightly with earth-brown midsoles, and outsoles finished with gum complexions. Peep a first look here, and note that they'll be dropping on December 21st for the standard $200 USD on adidas.com and select retailers.
For other news, the RECOUTURE adidas Campus 80 is returning soon in three colorways.
Updated (10/8/2020): Yeezy Mafia shares a first look at the adidas Yeezy 700 v3 "Clay Brown".
Yeezy 700 v3 "Clay Brown"
Release Date: Dec 21st, 2020
Color: N/A
Mens: $200 Style Code: N/A
Make sure to follow @kicksfinder for live tweets during the release date.
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paragon_recruit Automotive embedded products
This position acts as the internal expert in and is responsible for the assessment of products designed in North America to ensure that they meet all company, customer and inherent Cyber Security requirements. Discovers these risks through penetration testing, specification, code review, and interpreting Security Bulletins published by various security organizations such as the FBI, Department of Homeland Security, Auto-ISAC, etc.
Programming knowledge and hacking is important. This role will assess products and find out if there's a way for a hacker to get in and take the product over. The products are communicating to the vehicle and internet.
This position will analyze customer requirements and assess from those requirements what threats are out there and develop a security plan for the products.
Documentation is important. Will work and train with the design engineers who are developing the product.
Specific responsibilities include:
Minimum Qualifications:
Preferred Qualifications:
To apply for this job email your details to firstname.lastname@example.com


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Cholera: Prevention
Am I at risk for getting cholera?
People who do not live in or visit areas where sanitation is poor have almost no risk of getting cholera. Even for people who do live in or visit such areas, the risks are not great.
Here are some precautions that can reduce your risk of getting cholera if you are in an area where it is widespread:
- Drink only bottled, boiled, or chemically treated water or carbonated beverages. When using bottled drinks, make sure that the seal has not already been broken.
- Avoid tap water and ice cubes made from tap water.
- If bottled water is not available, you can disinfect water by boiling it for one minute or filtering it, and then adding two drops of household bleach or half of an iodine tablet per liter of water.
- Wash your hands with soap and clean water every time you use the bathroom, and before you eat or prepare food. If soap and water are not available, use an alcohol-based hand cleaner that is at least 60% alcohol.
- Eat foods that are pre-packaged or that are freshly cooked and served hot. Avoid raw and undercooked meats and seafood or unpeeled fruits and vegetables.
- Dispose of feces in a place away from water that is used for drinking or food, especially if you have had cholera.
Is there a vaccine for cholera?
In 2016, the U.S. Food and Drug Administration approved a single-dose live oral cholera vaccine called Vaxchora® for adults 18 to 64 years old who are traveling to areas known to be affected by the most common bacterial strain of cholera. The vaccine is not recommended for most travelers from the United States, as most tourists do not visit areas with active cholera transmission. The vaccine is not 100% effective, so people who get it still need to use caution when traveling to areas known to have cholera.
There are 2 other oral vaccines for cholera, but they are they not available in the United States. If you work for an organization that is based outside the United States and travel to areas known to have cholera, you may be able to access 1 of them. Both require 2 doses to be most effective.


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Braingate System Full seminar reports, pdf seminar abstract, ppt, presentation, project idea, latest technology details, Ask Latest information. seminar report on brain gate-computer science. The device was designed to help those who have lost control of their limbs or other body function. The computer. BRAINGATE. SEMINAR REPORT INTRODUCTION BrainGate is a brain implant system developed by the biotech company Cyberkinetics in in.
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BrainGate is a brain implant system developed by the bio-tech company Cyberkinetics in in conjunction with the Department of Neuroscience braingatd Brown University. The device was designed to help those who have lost control of their limbs, or other bodily functions, such as patients with amyotrophic lateral sclerosis ALS or spinal cord injury. The computer chip, which is implanted into the brainmonitors brain activity in the patient and converts the intention of the user into computer commands.
Cyberkinetics describes that "such applications may include novel communications interfaces for motor impaired patients, as well as the monitoring and treatment of certain diseases which manifest themselves in patterns of brain activity, such as epilepsy and depression. The activities are translated into electrically braaingate signals and are then sent and decoded using a program, which can move either a robotic braigate or a computer cursor.
According to the Cyberkinetics' website, three patients have been implanted with the Braingae system. The company has confirmed that one patient Matt Nagle has a spinal cord injury, while another has advanced ALS.
The system is designed to restore functionality for a limited, immobile group of severely motor-impaired individuals. It is expected that people using the BrainGate System will employ a personal semiinar as the gateway to a range of self-directed activities. These activities may extend beyond typical computer functions e.
Braingate System Full Seminar Report, abstract and Presentation download
The BrainGate System is based on Cyberkinetics' platform technology to sense, transmit, analyze and apply the language of neurons. The System consists of a sensor that is implanted on the motor cortex of the brain and a device that analyzes brain signals. The principle of operation behind the BrainGate Seminad is that with intact brain function, brain signals are generated even though they are not sent to the arms, hands and legs.
The signals are interpreted and translated into cursor movements, offering the user an alternate "BrainGate pathway" to control a computer with thought, just as individuals seeminar have the ability to move their hands use a mouse. IBM, in partnership with scientists at Seminarr Ecole Polytechnique Federale de Lausanne's EPFL Brain and Mind Institute will begin simulating the brain's biological systems and output the data as a working 3-dimensional model that will recreate the high-speed electro-chemical interactions that take place within the brain's interior.
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These include cognitive functions such as language, learning, perception and memory in addition to brain malfunction such as psychiatric disorders like depression and autism.
From there, the modeling will expand to other regions of the brain and, if successful, shed light on the relationships between genetic, molecular and cognitive functions of the brain. Reprot braingate pilot device consists of a Sensor of the size of a contact lens, a cable and pedestal, which connects the chip to the computer, a cart which consists the signal processing unit.
The BrainGate Neural Braingaate Device is a proprietary brain-computer interface that consists of an internal neural signal sensor and external processors that convert neural signals into an output signal under the users own braignate. The sensor consists of a tiny chip smaller than a baby aspirin, with one hundred electrode sensors each thinner than a hair that detect brain repkrt electrical activity.
The chip is implanted on the surface of the brain in the motor cortex area that controls movement. In the pilot version of the device, a cable connects the sensor to an external signal processor in a cart that contains computers. The computers translate brain activity and create the communication output using custom decoding software.
Importantly, the entire BrainGate system was specifically designed for clinical use in humans and thus, its manufacture, assembly and testing are intended to meet human safety requirements.
Five quadriplegics patients in all are enrolled in the pilot study, which was approved by the U. There will be two surgeries, one to implant the BrainGate and one to remove it. Before surgery, there will be several precautionary measures in order to prevent infection; patients will have daily baths with antimicrobial soap and take antibiotics. In addition, MRI scans will be done to find the best place on the brain for the sensor.
Rwport sterile conditions and general anesthesia, Doctor will drill a small hole into the skull and implant the sensor using the same methods as in the monkey studies. Patients will receive post-surgical care including a CT scan, some blood tests, and wound care in the hospital for 1 briangate 5 days after surgery. After surgery, one of the study doctors will braingafe the patients at least once a week for six weeks, then monthly and as needed. A nurse will also check the patients regularly and will always carry a hour pager.
Braingate Seminar Report
The skin around the pedestal will need to be carefully monitored during the study. A brain-computer interface BCIsometimes called a direct neural interface or a brain-machine interface, is a direct communication pathway between a human or animal brain or brain cell culture and an external device.
In one-way BCIs, computers either accept commands from the brain or send signals to it for example, to restore vision but not both. Two-way BCIs would allow brains and external devices to exchange information in both directions but have yet to be successfully implanted in animals or humans. In this definition, the word brain means the brain or nervous system of an organic life form rather than the mind. Computer means any processing or computational device, from simple circuits to silicon chips including hypothetical future technologies such as quantum computing.
Research on BCIs began in the s, but it wasn't until the mids that the first working experimental implants in humans appeared. Following years of animal experimentation, early working implants in humans now exist, designed to restore damaged hearing, sight and movement.
The common thread throughout the research is the remarkable cortical plasticity of the brain, which often adapts to BCIs, treating prostheses controlled by implants as natural limbs. With recent advances in technology and knowledge, pioneering researchers could now conceivably attempt to produce BCIs that augment human functions rather than simply restoring them, previously only the realm of science fiction.
Neuroprosthetics is an area of neuroscience concerned with neural prostheses — using artificial devices to replace the function of impaired nervous systems or sensory organs. The most widely used neuroprosthetic device is the cochlear implant, which was implanted in approximatelypeople worldwide as of There are also several neuroprosthetic devices that aim to restore vision, including retinal implants, although this article only discusses implants directly into the brain. The differences between BCIs and neuroprosthetics are mostly in the ways the terms are used: Practical neuroprosthetics can be linked to any part of the nervous system, for example peripheral nerves, while the term "BCI" usually designates a narrower class of systems which interface with the central nervous system.
The terms are sometimes used interchangeably and for good reason. Neuroprosthetics and BCI seek to achieve the same aims, such as restoring sight, hearing, movement, ability to communicate, and even cognitive function.
Both use similar experimental methods and surgical techniques. A tiny wire connects the chip to a small pedestal secured in the scull. A cable connects the pedestal to a computer. Braingatr brain's bn neurons fire between 20 and times a second.
The sensor implanted in the brain senses these electrical signals and passes to the pedestal through the wire. The pedestal passes this signals to the computer through the cable.
The computer translates the signals into a communication output, allowing a person to move a cursor on a computer aeminar merely by thinking about it. The BrainGate System may offer substantial improvement over existing assistive technologies.
Currently available assistive devices have significant limitations for both the person in need and the caregiver. For example, even simple switches must be adjusted frequently, a process that can be time consuming. In addition, these devices are often obtrusive and may prevent the user from being able to simultaneously use the device and at the same time establish eye contact or carry on conversations with others. Potential advantages of the BrainGate System over other muscle driven or brain-based computer interface approaches include: Braingate Seminar Report Published on July 15, Are you interested in this topic.
Then mail to us immediately to get the full report.


text: Knowing I can inspire a beautiful day within myself first is the most powerful tool I have to inspire a beautiful life – day by day. This Post Has 0 Comments Leave a Reply Cancel replyYour email address will not be published. Required fields are marked *Name * Email * Website Comment


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The legend of Padmini, as told in a semi-fictional poem titled Padmavati, relates how Emperor Alauddin Khilji invaded Chittor after hearing of Padmini's beauty. The rani is supposed to have committed jauhar but historians suggest the events of Padmavati are meant to be treated as allegory rather than fact. At the end of January, Mr Bhansali was attacked in Jaipur by the Karni Sena over scenes that supposedly showed a romantic connection between Padmini and Alauddin Khilji. Later, tweets from the film official handle clarified that no such supposed dream sequence or song was ever scripted into the film.
Repeating. There NEVER was and never will be any scene or dream or song between #RaniPadmavati and #AlauddinKhilji in #Padmavati? Padmavati (@RealPadmavati) February 10, 2017
Repeating. #SanjayLeelaBhansali revers #RaniPadmavati and will NEVER do anything to hurt #Rajput sentiments. Do not believe otherwise? Padmavati (@RealPadmavati) February 10, 2017
Meanwhile, Ranveer Singh, who plays Alauddin Khilji, paid his director fulsome compliments while speaking to news agency IANS. "When I try to describe the way he is with actors, I run out of words. It's truly inexplicable the way he manages to extract great performances from his actors. It's just a gift that he has." Ranveer, 31, said. "I truly regard him as one of the greatest filmmakers of Hindi cinema in all time. His form and flamboyance are unique to him and there are some things that only he can do," he added, reports IANS.
Ranveer Singh is working with Sanjay Leela Bhansali for the third time after Goliyon Ki Raasleela Ram-Leela and Bajirao Mastani, films that also starred Deepika Padukone. Shahid Kapoor is collaborating with Mr Bhansali, Deepika and Ranveer for the first time. Padmavati is expected to release in November.


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EXTRADITION and FUGITIVE FROM JUSTICE DISMISSED – State v. Mr. S (DMC No. 10371) (Maricopa County Superior Court No. FB-P816358-CO; 96CR2263): Mr. S had been previously convicted of Larceny in the state of California and was order to pay $29,000 in restitution. He then "skipped probation" and ended up in Arizona. He subsequently was involved in a car accident, and picked up on a "Fugitive of Justice" warrant. We were able to work with the Prosecutor in the state of Colorado and, due to the fact that the case was 16 years old, we were able to have those charges dismissed. Once they were dismissed, the extradition proceeding pursuant to Arizona Revised Statute ARS 13-3845 and the fugitive of justice warrant pursuant to Arizona Revised Statute ARS 13-3842 were dismissed in their entirety, thereby allowing Mr. S to move forward with his life.
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Green Bay general manager Brian Gutekunst worked for the Chiefs as a scouting assistant for one season …Packers executive vice president director of football operations Russ Ball, a native of Moberly, Mo., worked for the Chiefs for 10 seasons , the final two in football operations.
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No matter what you do, expect that everything will. The way your Twin Flame found you, is. Well, it's hard at first but it becomes easier as you learn how to let go of your obsession.
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On its broadest level, this symposium aims to bring together scholars to discuss how the works of Vergil illuminate questions about genre and literary identity in the ancient world. In addition to looking at generic interplay in Vergil's poetry, we seek to examine the role that genre has played in Vergil's afterlife, both among his contemporaries and in later ages: how, particularly in relation to Vergil's poems, did genre create or elide perceived boundaries and/or affiliations between authors in antiquity? What cultural implications did explicit or implicit generic interplay have? How has genre shaped not only our understanding of Vergil and what it meant to be an Augustan poet, but our reception ('after' in another sense) of the earlier genres with which he engaged? What do we gain and lose by putting Vergil at the forefront of this narrative?
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Japan Itinerary & DIY Travel Guide for 4, 7, 10, 14, and 21 Days
Planning to make your way to the 'Land of the Rising Sun'? Follow this ultimate DIY travel guide in order to make the most of your Japan itinerary!READ MORE
Planning to make your way to the 'Land of the Rising Sun'? Follow this ultimate DIY travel guide in order to make the most of your Japan itinerary!READ MORE
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Proarte Twistgrip Deerfoot Stipple Brush – Medium
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Cisco Bug: CSCul37458 - No phone type on incoming call toast after jabber re-sign in
Last Modified
Dec 30, 2013
Products (1)
- Cisco Jabber for iPhone
Known Affected Releases
Description (partial)
Symptom: Jabber get a incoming call and resign-in. Get another incoming call : no phone type on the incoming call toast. Conditions: 1. Jabber get a incoming call, check the incoming call toast. 2. Jabber sign out and sign in. 3. Jabber get a incoming call, check the incoming call toast.
Bug details contain sensitive information and therefore require a Cisco.com account to be viewed.
Bug Details Include
- Full Description (including symptoms, conditions and workarounds)
- Status
- Severity
- Known Fixed Releases
- Related Community Discussions
- Number of Related Support Cases


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England National Team player and defender on the English Premier League side, Kyle Walker, regretted his acts that breach the lockdown order of Coronavirus (COVID-19) after he allegedly hosts a 'sex party' at his house.
The Manchester City player was said to have held a party in his flat, discovering Naija News with one of his allies alongside two other ladies.
However, many condemned the suspected 'sexy group' given that the player had previously advised his social media followers to adhere to the lockdown rules of COVID-19, as directed by the government and also advised by health agencies.
The Gazette Nigeria understands Walker was having the party at his flat in Cheshire on Tuesday night.
Meanwhile, he had tweeted this earlier: "Please, everyone stay home, look after one another through this difficult time and check in on loved ones but don't visit them," said Walker while advising his Twitter followers.
Walker has tendered his apologies and regretted his actions according to a UK Sun story.
"I want to take this opportunity to issue a public apology for the choices I made last week," said Walker, UK Sun report.
"I understand that my position as a professional footballer brings the responsibility of being a role model.
"As such, I want to apologise to my family, friends, football club, supporters, and the public for letting them down.
"There are heroes out there, making a vital difference to society at the moment, and I have been keen to help support and highlight their incredible sacrifices and life-saving work over the past week.
"My actions are in direct contrast to what I should have been doing regarding the lockdown."
In response to Walker's COVID-19 lockout breach, Manchester City on their part has said an internal disciplinary action will be taken on the player at the appropriate time.
The party affirmed: We are disappointed to hear the allegations, note Kyle's swift statement and apology, and will be conducting an internal disciplinary procedure in the coming days."


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The Natural
The Natural4.18 109 5 Author: Richard La Ruina Narrator: Steve West
More information about the audiobook:Publisher: HarperAudio
Published: 2015-11-17
Length: 5H 34Min
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Saturday, October 5, 2019
FB Scoop: Miss World Philippines Strips Off Miss Eco Teen Philippines Title from Vanessa Mae Walters
38 comments:
- AnonymousOctober 5, 2019 at 12:17 AM
Sa akin lang ha, di naman maganda si Vanessa. Mukhang mas ok tong si ZaideReplyDeleteReplies
- AnonymousOctober 5, 2019 at 6:38 PM
They didnt have to embarass the young girl by detailing the reasons for her removal.Delete
6:38 I think they needed to be detailed.Delete
Para wala nang eklavu as to why.
Also, she brought it upon herself.
like duh?
- AnonymousOctober 6, 2019 at 1:39 AM
Pag hindi dinetail, hahanapan ng tao bakit inalis. Pag dinetail, inembarass na. San lulugar?Delete
- AnonymousOctober 7, 2019 at 12:55 AM
Agree ako na ibigay ang reason para wala nang tanong tanongDelete
No need to sugar qoute it
- AnonymousOctober 7, 2019 at 10:11 AM
12:55 sugarcoat kasiDelete
- AnonymousOctober 5, 2019 at 12:19 AM
Vanessa's not that pretty naman. Salamat at natanggalan ng korona.ReplyDelete
- AnonymousOctober 5, 2019 at 12:22 AM
one month preparation for Mary? you can do it! you go girl!ReplyDelete
- AnonymousOctober 5, 2019 at 12:27 AM
Hirap sa inyo.. hnde naman kayo lumaki sa Pinas.. all your childhood in-embrace nio na ung culture kung san kau lumaki.. fast forward s young adult life nio.. gusto nio ng career or validation.. uuwe kayo ng Pinas ssali sa pageant coz aminin naman natin malaki ung advantage kpg my foreign blood mas stand out ung beauty...but during pageant all patriots nd nationalists kayo and after the pageant you cant even live with all your lies until matapos ang reign nio.. Stop using our poor motherlnd para sa pansariling interes nioReplyDeleteReplies
- AnonymousOctober 5, 2019 at 1:46 AM
Well said, 12:27.Delete
Laki ng ingit. Hindi nmn basehan ung pagiging puro pinoy oh hndi. Marami Jan pure pinoy na gustong magabroad eh.Delete
- AnonymousOctober 5, 2019 at 10:39 AM
well said.Delete
- AnonymousOctober 5, 2019 at 12:36 PM
- AnonymousOctober 5, 2019 at 2:19 PM
7:56 nagets mo ba sinabi ni 12:27? Para yun sa mga may lahing pinoy na lumaki sa ibang bansa, di kinikilala pagiging pinoy until nangarap sumali sa mga pageant or maging model kaya uuwi ng pinas para dito magpayaman dahil sabik at mabenta sa ibang pinoy ang may mga foreign blood.Delete
- AnonymousOctober 5, 2019 at 3:09 PM
7:56am excuse me... hinde naman s pagmamayabang resident nko ng dto s land down under walang reason pra mainggit ako.. but pra sa kahinaan ng ulo mo. Sana naman kung gagamitin nia ang Pinas for her own dreams sna kht papano may kontibg malasakit. Be respectful and during her reign sna ipakita nia na Filipina pa din sya kht by heart.. lahat tayo my pagk liberated dumaan s pag k liberated phase ng buhay ntn... pero it doesn't mean babastusin na ntn and isa pa wala pumilit s kanya sumali jan ginusyo nia so dpt be responsible gets???!Delete
- AnonymousOctober 9, 2019 at 1:24 AM
- AnonymousOctober 5, 2019 at 12:28 AM
Ay, may attitude si ate girl. May walkout pang nalalaman! Nalunod ata sa iisang basong tubig...ReplyDelete
- AnonymousOctober 5, 2019 at 12:29 AM
Go to ur own country and try mo sumali s bea-Con duonReplyDelete
- AnonymousOctober 5, 2019 at 12:35 AM
parang si Divine ng GMA7 si Vanessa eReplyDelete
Mabuti naman at na dethrone kasi hindi magandang ehemploReplyDelete
- AnonymousOctober 5, 2019 at 12:47 AM
Wala naman si Resurrecion sa top 22 man lang !??ReplyDeleteReplies
- AnonymousOctober 5, 2019 at 10:08 AM
Dahil ilan lang naman sila na teens sa MWDelete
- AnonymousOctober 5, 2019 at 12:13 PM
They had to pick someone who's actually in her teens AND would be available for the competition. Most likely, she is the one who fit the bill.Delete
- AnonymousOctober 5, 2019 at 1:27 PM
4 lang ang teens eh. So yung pinaka-okay ang ipinalit.Delete
- AnonymousOctober 5, 2019 at 12:50 AM
Eto yung claiming na she is studying at Harvard. HahahaReplyDeleteReplies
- AnonymousOctober 5, 2019 at 1:28 PM
19 y/o lang tapos law student na. Ano yun walang pre-law na tinapos. lolDelete
- AnonymousOctober 5, 2019 at 1:32 PM
Kaloka noh! Misrepresented her credentials ang isa sa mga dahilan ng dethronement. Dapat kasi nagi-imbestiga rin muna ang MWP organizers bago tumanggap ng contestant.Delete
- AnonymousOctober 5, 2019 at 7:16 PM
Ikr! HahahaDelete
- AnonymousOctober 6, 2019 at 1:52 AM
Walang ka proof proof sa social media nya na student sya sa Harvard. Ngek. Ang Pinoy kasi paniwala ng paniwala sa sabi sabi.Delete
- AnonymousOctober 5, 2019 at 12:56 AM
Nakakaloka na pinost niya to sa ig niya mismo.ReplyDelete
- AnonymousOctober 5, 2019 at 12:56 AM
nasobrahan nman kasi sa pagkaliberated. imagine 16 plang eh umiinom na sa bar. posting nude pics on socmed.ReplyDeleteReplies
- AnonymousOctober 5, 2019 at 6:14 AM
Well I started drinking and going out to bars when I was 15. Now I am 39 may magandang trabaho at maayos na pamilya. But when it comes to attitude, magalang at masunurin ako sa magulang. Di rin natin masasabi ang mangyayari sa batang yan kasi nga bata pa sya. Pwede pang magbago.Delete
- AnonymousOctober 5, 2019 at 12:27 PM
Basahin niyo yung comment dun sa post niya na may diamond ring.Delete
Baka joining a beaucon is her way of "promoting" herself
- AnonymousOctober 5, 2019 at 10:44 PM
I started drinking when I was 13. In my teens, I did literally everything my parents warned me not to do. I never talked back at them, though. Never walked out sa anything, never ditched events na kailangan kong puntahan, etc. 'Yung pagkaliberated ng isang tao, walang konek sa ugali niya or kung saan siya dadalhin ng universe. Ngayon maganda ang trabaho ko, tinatapos ko masters ko. Okay naman. Haha. Bottomline is, lahat pwedeng magbago.Delete
- AnonymousOctober 5, 2019 at 3:01 PM
grabe naging ms teen earth 2014 din pala to. anong magandang ehemplo sa kabataan ang ikina pananalo nito. buti naman at nalaman ng MW organization na kailangang putulin na ang sungay at pagiging mahadera ng swellhead na yan. deactivated na ang ig acct nyaReplyDelete
- AnonymousOctober 5, 2019 at 9:41 PM
Ewan ko kung anu iniisip nya nung pinost nya ung nude foto sa ig. Lam nman nya na may behavioural code pgging title holder. Bka sinadya para nga madethrone.ReplyDelete
- AnonymousOctober 6, 2019 at 12:04 AM
Pagcheck ko ng socmed nitong batang to, ang daming toxic don - people bashing her and people protecting her to the point na pinapalabas nilang Vanessa didn't do anything bad.ReplyDelete
Bottomline: parang trabaho yan, she was tasked to do her job but she failed to do it intentionally. No company will allow numerous failures kaya siya na dethrone. And she's failing more now trying to save face trying to be strong pero in reality her attitude is no where close having a crown. Sa ibang liga ka sumali ija. Wag sa beaucon na may restrictions at rules na susuwayin mo lang.
- AnonymousOctober 6, 2019 at 11:11 AM
Sa title holders ng MWP siya yun least na maganda pero isa sa matatalino.ReplyDelete


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Baseline Selling – How to Become a Sales Superstar by Using What You Already Know About the Game of Baseball, will dramatically change the way we. There are many books on selling and each has an angle that seeks differentiate it from others. Dave Kurlan develops sales people and is also a baseball fan. Baseline Selling was founded in by Dave Kurlan and is fully described in his book Baseline Selling: How to Become a Sales Superstar by.
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Biotech R&D is on a roll. For the third year in a row, the life sciences group at BDO has tracked a spike in R&D spending at a wide swath of public biotechs in the U.S. For drug developers with $50 million to $300 million in revenue, research budgets swelled 28%--to an average of $137 million--last year.
The jump comes at a time investors remain eager buyers of many biotech stocks, pumping billions of dollars into small upstarts as well as the larger and more mature biotechs. Equity financing was the way to go in 2013, with biotechs gaining an average of $81 million--another 28% spike--when they turned to the market. But even a small number relying on debt financing did well last year, raising an average of $85 million.
In order to get a clear look at a representative group of middle-market biotechs, BDO excluded the really big players with revenue over $300 million from their index.
This is a market, though, that favors the strong and disadvantages the weak. The smaller--under $50 million companies in the bunch--posted a slight decline in research spending last year, says BDO. Looked at as a whole, the average R&D budget hit $56.5 million in 2013, up from $49.5 million in 2012 and $44 million in 2011.
|BDO's Ryan Starkes
"What was good to see was the consistency; the continued growth in the industry and the investment in the science," says BDO life sciences group leader Ryan Starkes. The key to this trend, he says, is "the overall ability for companies to access the capital markets, to get that investment."
Just how essential that is was underscored by another key figure in their report. The average loss in this group hit $65 million last year, up from $38 million in 2011. And close to 9 out of 10 of these companies reported some kind of loss. Without the investment into research and the promise of a payoff down the road with a new drug approval or a company buyout, there wouldn't be any money to invest in R&D.
These numbers represent a sharp turnaround from the capital-restricted days of 2008-2010. Of course, the 85% average shareholder return that investors gleaned in 2013 hasn't hurt the sentiment about investing more in biotech. So when does this upward cycle end?
"I'm not sure when you would necessarily see a stop," adds Starkes. "As for a slowdown in dollars and growth, we'll have to see how it plays out." But with new approvals shooting up this year, the near term continues to look good.
- here's the release


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No announcement yet.
new posts
Even I'd prefer fondaparinux.
Leave a comment:
Thank you for you for your response, the baby is now 5 weeks old and no bruising has been noted. At this time the mother is taking 2.5 mg of Elliquist twice daily without incidence. I will forward this data to her hematologist for review. As started earlier the mother is HIT Positive so we are left with little alternatives
Leave a comment:
Fondaparinux sodium (Arixtra) is rated an L3-no data-probably compatible. "As a pentasaccharide, it would neither be likely to enter the milk compartment due to its large molecular weight, or be orally bioavailable in an infant if any drug managed to reach the milk compartment. No data are available on the transmission of fondaparinux sodium to a nursing infant, but based on the kinetic profile it is highly unlikely that it would be passed to the infant." (Medications and Mothers' Milk database, Dr Thomas Hale PhD). Monitor your infant for rare-bruising on the skin, blood in urine, vomit or stool.
Apixaban (Eliquis) is rated an L4-no data-possibly hazardous. "At this time there are no data regarding the transfer of apixaban into human milk. The manufacturer reports that apixaban is excreted into rodent milk (about 12% of the maternal dose). Based on this medications small volume of distribution and high pKa it will likely enter human milk. At this time we recommend the use of alternatives with more data in lactation (e.g. LMWH, warfarin) when suitable to treat the maternal condition." (Medications and Mothers' Milk database, Dr Thomas Hale PhD).
Sandra Lovato R.N.
InfantRisk Center
Leave a comment:
My daughter was diagnosed with Factor V Leiden, back in 2011 to complicate matters she has Heparin-induced thrombocytopenia and May-Thurner syndrome (MTS). Last year she found out that she was pregnant and the search was on to find a safe blood thinner that would allow for her to breast feed. Prior to her pregnancy she was prescribed Ellquis, thru out her pregnancy she was given Fondapariux Injections
The Lactation Consultant at the Labor & Delivery unit verified that this combination would be safe for her to use during breast-feeding. Her baby is now 1 week old and they successful bridged her over from the fondaparinux injections back to ellquis all while the baby breast fed, there have been no issues to date. The baby was delivered at Tampa General Hospital's Women's Center. in Tampa, Florida
Leave a comment:
First let me describe something about molecular weight and transfer into human milk. The first 4-6 days postpartum, the milk compartment is quite open and porous and most any drug can readily enter colostrum at this point. That said, the volume of colostrum is so low (30-60 cc per day) that ultimately the absolute mg dose transferred to the infant is infinitesimally low. So we don't really worry too much about drugs during the colostral phase (first 4-6 days). After about 6 days, the milk volume increases rapidly to about 400-600 cc per day. This is when we carefully consider the dose of the drug transferred via milk. Also, after 6 days, the milk compartment tightens up significantly and becomes very similar to the blood-brain barrier, where drugs must be small in molecular weight ( < 700 daltons), and quite lipophilic, and non-polar, to enter the milk compartment. It really is very similar to the blood-brain barrier.
Hence with fondaparinux, heparin, low molecular weight heparins, etc, the high molecular weights of these products virtually eliminate their entry into human milk, after 4 days. We have good data on the LMW heparins, and heparin that confirms this.
While we do not have data on fondaparinux, I am quite certain that it would not enter milk much after 4 days, and due to its structure, it would not be orally bioavailable in the infant, as it would be totally unstable in the infants gut. For the first four days postpartum, I would assume that it would enter colostrum at about the same level as is in the plasma, but the limited volume of colostrum and its poor oral bioavailability would probably preclude absorption of very much if any at all.
As Danaparoid, I think it has been withdrawn in the USA, but may still be available elsewhere. It is a derivative of heparin, and similarly would not likely be orally bioavailable or likely penetrate mature milk.
Personally, I'd prefer fondaparinux.
Tom Hale PH.D.
Leave a comment:
FondaparinuxCould I ask your advice please? I am a pharmacist. We have a patient who we are treating with fondaparinux in pregnancy and who would very much like to breastfeed. She cannot have low molecular weight heparins but danaparoid is also a possibility although it is more difficult to give. I have looked through your previous postings and see you have said fondaparinux would be safe previously but I also saw a posting on danaparoid which said you would not give in the first few days postnatally as it might appear in colostrum. Why is this and which of the two drugs would you prefer to give in a breastfeeding mother?
Thanks very much for your helpTags: None